phewas_code phewas_string sex MatchedCases MatchedControls groupnum group color N N_Q1 N_Q2 N_Q3 N_Q4 PRS_BETA PRS_SEBETA PRS_P PRS_LOG10P PRS_OR PRS_CI1 PRS_CI2 Q1Q2_BETA Q1Q2_SEBETA Q1Q2_P Q1Q2_LOG10P Q1Q2_OR Q1Q2_CI1 Q1Q2_CI2 Q1Q3_BETA Q1Q3_SEBETA Q1Q3_P Q1Q3_LOG10P Q1Q3_OR Q1Q3_CI1 Q1Q3_CI2 Q1Q4_BETA Q1Q4_SEBETA Q1Q4_P Q1Q4_LOG10P Q1Q4_OR Q1Q4_CI1 Q1Q4_CI2 predictor exclude 008 Intestinal infection Both 1196 4423 1 infectious diseases blue 4423, 1196 1105, 296 1106, 289 1105, 334 1106, 277 0.0155 0.0327 0.635 0.1972 1.02 0.953 1.08 -0.0167 0.0933 0.858 0.0666 0.983 0.819 1.18 0.126 0.091 0.166 0.7811 1.13 0.949 1.36 -0.0623 0.0942 0.508 0.2943 0.94 0.781 1.13 PRS_PLINK_2.51188643150958e.06 FALSE 008.5 Bacterial enteritis Both 604 2058 1 infectious diseases blue 2058, 604 514, 148 514, 150 514, 180 515, 126 0.00456 0.0458 0.921 0.03586 1 0.918 1.1 0.0127 0.133 0.924 0.0343 1.01 0.781 1.31 0.192 0.129 0.135 0.8682 1.21 0.942 1.56 -0.163 0.137 0.235 0.6296 0.849 0.649 1.11 PRS_PLINK_2.51188643150958e.06 FALSE 008.52 Intestinal infection due to C. difficile Both 471 1617 1 infectious diseases blue 1617, 471 405, 122 404, 111 404, 133 404, 105 0.0168 0.052 0.747 0.1266 1.02 0.918 1.13 -0.0928 0.151 0.538 0.2691 0.911 0.678 1.22 0.0769 0.145 0.596 0.2247 1.08 0.813 1.44 -0.135 0.152 0.374 0.4274 0.874 0.649 1.18 PRS_PLINK_2.51188643150958e.06 FALSE 008.6 Viral Enteritis Both 320 1240 1 infectious diseases blue 1240, 320 310, 71 310, 93 310, 79 310, 77 0.106 0.0635 0.0945 1.024 1.11 0.982 1.26 0.253 0.178 0.154 0.8111 1.29 0.909 1.83 0.0681 0.183 0.709 0.1494 1.07 0.749 1.53 0.0818 0.184 0.657 0.1825 1.09 0.757 1.56 PRS_PLINK_2.51188643150958e.06 FALSE 010 Tuberculosis Both 71 333 1 infectious diseases blue 333, 71 83, 19 83, 20 83, 16 83, 16 -0.0854 0.111 0.442 0.3545 0.918 0.739 1.14 0.137 0.361 0.704 0.1527 1.15 0.565 2.33 -0.147 0.377 0.696 0.1574 0.863 0.412 1.81 -0.214 0.38 0.573 0.2419 0.807 0.383 1.7 PRS_PLINK_2.51188643150958e.06 FALSE 031 Diseases due to other mycobacteria Both 39 119 1 infectious diseases blue 119, 39 30, 16 30, 9 29, 9 30, 5 -0.303 0.175 0.0835 1.078 0.738 0.524 1.04 -0.604 0.563 0.283 0.5479 0.547 0.182 1.65 -0.36 0.537 0.503 0.2987 0.698 0.244 2 -0.899 0.595 0.131 0.8827 0.407 0.127 1.31 PRS_PLINK_2.51188643150958e.06 TRUE 038 Septicemia Both 1044 3452 1 infectious diseases blue 3452, 1044 862, 253 863, 228 863, 266 863, 297 0.0707 0.0366 0.0535 1.272 1.07 0.999 1.15 -0.093 0.103 0.369 0.4334 0.911 0.744 1.12 0.0572 0.101 0.57 0.2443 1.06 0.869 1.29 0.158 0.0988 0.109 0.9617 1.17 0.965 1.42 PRS_PLINK_2.51188643150958e.06 FALSE 038.1 Gram negative septicemia Both 278 838 1 infectious diseases blue 838, 278 210, 62 209, 68 209, 60 210, 88 0.141 0.0786 0.0719 1.143 1.15 0.987 1.34 0.105 0.203 0.603 0.2194 1.11 0.746 1.65 -0.0529 0.21 0.802 0.09603 0.949 0.628 1.43 0.337 0.197 0.0863 1.064 1.4 0.953 2.06 PRS_PLINK_2.51188643150958e.06 FALSE 038.2 Gram positive septicemia Both 102 331 1 infectious diseases blue 331, 102 83, 24 83, 26 82, 23 83, 29 0.0827 0.116 0.477 0.3214 1.09 0.865 1.36 0.042 0.325 0.897 0.04705 1.04 0.551 1.97 0.0503 0.339 0.882 0.05447 1.05 0.541 2.04 0.234 0.325 0.473 0.3256 1.26 0.668 2.39 PRS_PLINK_2.51188643150958e.06 FALSE 038.3 Bacteremia Both 555 1690 1 infectious diseases blue 1690, 555 423, 122 422, 139 422, 120 423, 174 0.0897 0.0509 0.0781 1.107 1.09 0.99 1.21 0.13 0.142 0.361 0.4426 1.14 0.862 1.5 -0.00318 0.147 0.983 0.007538 0.997 0.747 1.33 0.365 0.138 0.00809 2.092 1.44 1.1 1.89 PRS_PLINK_2.51188643150958e.06 FALSE 041 Bacterial infection NOS Both 1870 5160 1 infectious diseases blue 5160, 1870 1289, 454 1290, 461 1290, 477 1290, 478 0.0089 0.0271 0.743 0.129 1.01 0.957 1.06 0.00625 0.0773 0.936 0.0289 1.01 0.865 1.17 0.044 0.0769 0.568 0.246 1.04 0.899 1.21 0.0541 0.077 0.482 0.3166 1.06 0.908 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 041.1 Staphylococcus infections Both 549 2320 1 infectious diseases blue 2320, 549 580, 126 580, 140 580, 132 580, 151 0.0482 0.0487 0.322 0.4926 1.05 0.954 1.15 0.124 0.136 0.363 0.4407 1.13 0.867 1.48 0.0737 0.139 0.595 0.2253 1.08 0.82 1.41 0.178 0.136 0.189 0.7237 1.19 0.916 1.56 PRS_PLINK_2.51188643150958e.06 FALSE 041.11 Methicillin sensitive Staphylococcus aureus Both 328 1245 1 infectious diseases blue 1245, 328 312, 68 311, 88 311, 81 311, 91 0.012 0.0616 0.846 0.07271 1.01 0.897 1.14 0.235 0.182 0.196 0.7079 1.26 0.886 1.81 0.189 0.185 0.307 0.5133 1.21 0.841 1.74 0.277 0.185 0.134 0.873 1.32 0.918 1.89 PRS_PLINK_2.51188643150958e.06 FALSE 041.12 Methicillin resistant Staphylococcus aureus Both 251 1087 1 infectious diseases blue 1087, 251 272, 63 272, 52 271, 59 272, 77 0.0757 0.079 0.338 0.471 1.08 0.924 1.26 -0.151 0.208 0.468 0.3301 0.86 0.572 1.29 -0.0263 0.203 0.897 0.04716 0.974 0.654 1.45 0.191 0.194 0.323 0.4901 1.21 0.828 1.77 PRS_PLINK_2.51188643150958e.06 FALSE 041.2 Streptococcus infection Both 569 2321 1 infectious diseases blue 2321, 569 581, 152 580, 143 580, 132 580, 142 -0.0122 0.0472 0.796 0.09903 0.988 0.901 1.08 -0.0318 0.131 0.808 0.09245 0.969 0.749 1.25 -0.122 0.133 0.362 0.4417 0.885 0.682 1.15 -0.0534 0.132 0.686 0.1635 0.948 0.732 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 041.21 Rheumatic fever / chorea Both 56 380 1 infectious diseases blue 380, 56 95, 25 95, 14 95, 7 95, 10 -0.388 0.144 0.00693 2.16 0.678 0.512 0.899 -0.487 0.367 0.184 0.7348 0.615 0.3 1.26 -1.14 0.438 0.00894 2.049 0.319 0.135 0.751 -0.854 0.397 0.0314 1.503 0.426 0.196 0.927 PRS_PLINK_2.51188643150958e.06 FALSE 041.4 E. coli Both 508 1769 1 infectious diseases blue 1769, 508 443, 124 442, 127 442, 144 442, 113 0.0106 0.0519 0.839 0.07629 1.01 0.913 1.12 0.0443 0.144 0.758 0.1205 1.05 0.789 1.39 0.155 0.141 0.271 0.5668 1.17 0.886 1.54 -0.0659 0.148 0.657 0.1827 0.936 0.7 1.25 PRS_PLINK_2.51188643150958e.06 FALSE 041.8 H. pylori Both 107 406 1 infectious diseases blue 406, 107 102, 30 101, 22 101, 30 102, 25 -0.101 0.106 0.342 0.4657 0.904 0.734 1.11 -0.241 0.313 0.442 0.3549 0.786 0.426 1.45 -0.0125 0.3 0.967 0.01468 0.988 0.548 1.78 -0.14 0.309 0.649 0.1877 0.869 0.474 1.59 PRS_PLINK_2.51188643150958e.06 FALSE 041.9 Infection with drug-resistant microorganisms Both 176 525 1 infectious diseases blue 525, 176 132, 40 131, 46 131, 46 131, 44 0.105 0.0908 0.248 0.6052 1.11 0.929 1.33 0.281 0.257 0.274 0.5628 1.32 0.801 2.19 0.188 0.254 0.46 0.3374 1.21 0.734 1.98 0.156 0.258 0.545 0.2637 1.17 0.705 1.94 PRS_PLINK_2.51188643150958e.06 FALSE 053 Herpes zoster Both 610 1995 1 infectious diseases blue 1995, 610 499, 156 499, 162 498, 152 499, 140 -0.012 0.0459 0.794 0.1 0.988 0.903 1.08 0.049 0.13 0.706 0.1512 1.05 0.814 1.35 -0.0272 0.131 0.836 0.07776 0.973 0.752 1.26 -0.113 0.134 0.396 0.402 0.893 0.687 1.16 PRS_PLINK_2.51188643150958e.06 FALSE 053.1 Herpes zoster with nervous system complications Both 98 293 1 infectious diseases blue 293, 98 74, 18 73, 33 73, 19 73, 28 0.0552 0.118 0.639 0.1947 1.06 0.839 1.33 0.536 0.348 0.124 0.9083 1.71 0.864 3.38 0.129 0.376 0.732 0.1353 1.14 0.544 2.38 0.383 0.346 0.268 0.5725 1.47 0.745 2.89 PRS_PLINK_2.51188643150958e.06 FALSE 054 Herpes simplex Both 548 1879 1 infectious diseases blue 1879, 548 470, 117 470, 165 469, 134 470, 132 0.0539 0.048 0.261 0.5829 1.06 0.961 1.16 0.353 0.138 0.0105 1.98 1.42 1.09 1.86 0.133 0.143 0.351 0.4545 1.14 0.863 1.51 0.133 0.143 0.352 0.4537 1.14 0.863 1.51 PRS_PLINK_2.51188643150958e.06 FALSE 070 Viral hepatitis Both 232 969 1 infectious diseases blue 969, 232 243, 64 242, 51 242, 61 242, 56 -0.0137 0.0707 0.846 0.07267 0.986 0.859 1.13 -0.186 0.211 0.378 0.4223 0.83 0.549 1.26 -0.115 0.203 0.572 0.2425 0.892 0.599 1.33 -0.151 0.209 0.472 0.3265 0.86 0.57 1.3 PRS_PLINK_2.51188643150958e.06 FALSE 070.1 Viral hepatitis A Both 26 100 1 infectious diseases blue 100, 26 25, 9 25, 1 25, 11 25, 5 -0.157 0.197 0.428 0.3689 0.855 0.581 1.26 -2.22 0.976 0.0228 1.643 0.108 0.016 0.734 0.236 0.625 0.706 0.1509 1.27 0.371 4.31 -0.9 0.684 0.188 0.7258 0.407 0.107 1.55 PRS_PLINK_2.51188643150958e.06 TRUE 070.2 Viral hepatitis B Both 76 232 1 infectious diseases blue 232, 76 58, 21 58, 15 58, 20 58, 20 0.000635 0.135 0.996 0.001637 1 0.768 1.3 -0.385 0.408 0.345 0.4626 0.68 0.306 1.51 -0.0619 0.386 0.872 0.05924 0.94 0.441 2 -0.116 0.381 0.762 0.1183 0.891 0.422 1.88 PRS_PLINK_2.51188643150958e.06 FALSE 070.3 Viral hepatitis C Both 119 620 1 infectious diseases blue 620, 119 155, 30 155, 32 155, 33 155, 24 0.0117 0.098 0.905 0.04335 1.01 0.835 1.23 0.0999 0.282 0.723 0.1406 1.11 0.636 1.92 0.0861 0.275 0.754 0.1226 1.09 0.636 1.87 -0.065 0.304 0.83 0.0807 0.937 0.517 1.7 PRS_PLINK_2.51188643150958e.06 FALSE 070.4 Chronic hepatitis Both 76 243 1 infectious diseases blue 243, 76 61, 26 61, 18 60, 18 61, 14 -0.113 0.133 0.393 0.4054 0.893 0.689 1.16 -0.392 0.379 0.3 0.5224 0.676 0.322 1.42 -0.295 0.371 0.426 0.3702 0.745 0.36 1.54 -0.504 0.388 0.194 0.7116 0.604 0.282 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 070.9 Hepatitis NOS Both 327 1380 1 infectious diseases blue 1380, 327 345, 78 345, 88 345, 82 345, 79 0.0773 0.0636 0.224 0.649 1.08 0.954 1.22 0.153 0.175 0.382 0.4182 1.17 0.827 1.64 0.0404 0.177 0.82 0.08645 1.04 0.736 1.47 0.0173 0.179 0.923 0.03476 1.02 0.716 1.45 PRS_PLINK_2.51188643150958e.06 FALSE 071 Human immunodeficiency virus [HIV] disease Both 61 155 1 infectious diseases blue 155, 61 39, 15 39, 12 38, 17 39, 17 0.00517 0.134 0.969 0.01363 1.01 0.774 1.31 -0.23 0.478 0.63 0.2004 0.794 0.311 2.03 -0.0539 0.442 0.903 0.04433 0.948 0.398 2.25 -0.0451 0.464 0.923 0.03501 0.956 0.385 2.37 PRS_PLINK_2.51188643150958e.06 FALSE 071.1 HIV infection, symptomatic Both 51 113 1 infectious diseases blue 113, 51 29, 13 28, 11 28, 15 28, 12 -0.141 0.16 0.379 0.4216 0.869 0.635 1.19 -0.375 0.58 0.518 0.2858 0.687 0.221 2.14 0.205 0.513 0.69 0.1613 1.23 0.449 3.36 -0.14 0.545 0.798 0.09803 0.87 0.299 2.53 PRS_PLINK_2.51188643150958e.06 FALSE 078 Viral warts & HPV Both 1119 3378 1 infectious diseases blue 3378, 1119 845, 268 844, 293 844, 274 845, 284 0.0457 0.0351 0.193 0.7136 1.05 0.977 1.12 0.0865 0.098 0.377 0.4231 1.09 0.9 1.32 0.0124 0.0992 0.901 0.0454 1.01 0.834 1.23 0.05 0.0985 0.612 0.2134 1.05 0.867 1.28 PRS_PLINK_2.51188643150958e.06 FALSE 079 Viral infection Both 2220 3979 1 infectious diseases blue 3979, 2220 994, 500 995, 582 994, 570 995, 568 0.0627 0.0269 0.0197 1.705 1.06 1.01 1.12 0.156 0.0767 0.0418 1.379 1.17 1.01 1.36 0.135 0.0765 0.0781 1.108 1.14 0.985 1.33 0.133 0.0768 0.0829 1.082 1.14 0.983 1.33 PRS_PLINK_2.51188643150958e.06 FALSE 079.1 Varicella infection Both 1290 3695 1 infectious diseases blue 3695, 1290 923, 289 924, 328 923, 329 924, 344 0.0709 0.033 0.0319 1.496 1.07 1.01 1.15 0.117 0.0946 0.217 0.6645 1.12 0.934 1.35 0.121 0.0937 0.195 0.71 1.13 0.94 1.36 0.17 0.0932 0.0677 1.169 1.19 0.988 1.42 PRS_PLINK_2.51188643150958e.06 FALSE 079.2 Infectious mononucleosis Both 67 260 1 infectious diseases blue 260, 67 65, 11 65, 10 65, 23 65, 23 0.117 0.127 0.356 0.449 1.12 0.877 1.44 -0.0823 0.479 0.863 0.06376 0.921 0.36 2.35 0.766 0.412 0.0632 1.2 2.15 0.959 4.83 0.614 0.411 0.135 0.8681 1.85 0.825 4.13 PRS_PLINK_2.51188643150958e.06 FALSE 079.9 Viremia, NOS Both 317 936 1 infectious diseases blue 936, 317 234, 74 234, 85 234, 77 234, 81 -0.00781 0.0619 0.9 0.04595 0.992 0.879 1.12 0.142 0.187 0.447 0.3495 1.15 0.799 1.66 0.0452 0.19 0.811 0.09076 1.05 0.722 1.52 0.106 0.188 0.575 0.2401 1.11 0.768 1.61 PRS_PLINK_2.51188643150958e.06 FALSE 080 Postoperative infection Both 772 4044 1 infectious diseases blue 4044, 772 1011, 198 1011, 194 1011, 191 1011, 189 0.0222 0.0396 0.576 0.2397 1.02 0.946 1.11 0.000644 0.111 0.995 0.002018 1 0.805 1.24 -0.0224 0.111 0.84 0.07566 0.978 0.787 1.22 -0.024 0.111 0.829 0.0812 0.976 0.785 1.21 PRS_PLINK_2.51188643150958e.06 FALSE 081 Infection/inflammation of internal prosthetic device; implant; and graft Both 528 2351 1 infectious diseases blue 2351, 528 588, 134 588, 142 587, 117 588, 135 0.0143 0.0486 0.769 0.1143 1.01 0.922 1.12 0.0818 0.135 0.543 0.265 1.09 0.834 1.41 -0.116 0.14 0.405 0.3923 0.89 0.677 1.17 0.0111 0.136 0.935 0.02927 1.01 0.774 1.32 PRS_PLINK_2.51188643150958e.06 FALSE 090 Sexually transmitted infections (not HIV or hepatitis) Both 323 1541 1 infectious diseases blue 1541, 323 386, 82 385, 70 385, 87 385, 84 0.0415 0.0614 0.499 0.3016 1.04 0.924 1.18 -0.159 0.18 0.377 0.4231 0.853 0.6 1.21 0.0909 0.171 0.595 0.2255 1.1 0.783 1.53 0.00882 0.172 0.959 0.01817 1.01 0.72 1.41 PRS_PLINK_2.51188643150958e.06 FALSE 110 Dermatophytosis / Dermatomycosis Both 1374 3909 1 infectious diseases blue 3909, 1374 977, 347 977, 360 977, 344 977, 323 0.0144 0.0319 0.652 0.1855 1.01 0.953 1.08 0.0312 0.0888 0.725 0.1395 1.03 0.867 1.23 0.0139 0.0902 0.878 0.05664 1.01 0.85 1.21 -0.0732 0.0912 0.422 0.3748 0.929 0.777 1.11 PRS_PLINK_2.51188643150958e.06 FALSE 110.1 Dermatophytosis Both 1294 3569 1 infectious diseases blue 3569, 1294 892, 331 892, 343 892, 314 892, 306 0.00696 0.033 0.833 0.07948 1.01 0.944 1.07 0.0285 0.0914 0.755 0.1221 1.03 0.86 1.23 -0.0215 0.0937 0.819 0.0869 0.979 0.815 1.18 -0.0824 0.0939 0.38 0.4197 0.921 0.766 1.11 PRS_PLINK_2.51188643150958e.06 FALSE 110.11 Dermatophytosis of nail Both 883 2362 1 infectious diseases blue 2362, 883 590, 242 590, 225 590, 210 591, 206 -0.002 0.0408 0.961 0.01735 0.998 0.921 1.08 -0.0672 0.111 0.544 0.2646 0.935 0.753 1.16 -0.0929 0.113 0.411 0.3862 0.911 0.73 1.14 -0.135 0.113 0.233 0.633 0.874 0.7 1.09 PRS_PLINK_2.51188643150958e.06 FALSE 110.12 Althete's foot Both 392 1187 1 infectious diseases blue 1187, 392 297, 82 297, 97 296, 103 297, 110 0.0987 0.0611 0.106 0.9746 1.1 0.979 1.24 0.181 0.173 0.295 0.53 1.2 0.854 1.68 0.24 0.171 0.16 0.7953 1.27 0.909 1.78 0.299 0.168 0.0757 1.121 1.35 0.97 1.88 PRS_PLINK_2.51188643150958e.06 FALSE 110.13 Dermatophytosis of the body Both 282 1034 1 infectious diseases blue 1034, 282 259, 66 258, 69 258, 91 259, 56 -0.0124 0.0637 0.846 0.07258 0.988 0.872 1.12 0.0718 0.195 0.712 0.1473 1.07 0.733 1.57 0.313 0.184 0.09 1.046 1.37 0.952 1.96 -0.19 0.203 0.35 0.4565 0.827 0.556 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 110.2 Dermatomycoses Both 115 568 1 infectious diseases blue 568, 115 142, 26 142, 22 142, 40 142, 27 0.151 0.103 0.141 0.8517 1.16 0.951 1.42 -0.0544 0.319 0.864 0.06325 0.947 0.507 1.77 0.472 0.279 0.0909 1.041 1.6 0.928 2.77 0.0958 0.303 0.751 0.1241 1.1 0.608 1.99 PRS_PLINK_2.51188643150958e.06 FALSE 112 Candidiasis Both 1394 3990 1 infectious diseases blue 3990, 1394 998, 343 997, 354 997, 346 998, 351 0.0235 0.0314 0.453 0.3435 1.02 0.963 1.09 0.0362 0.0883 0.682 0.1665 1.04 0.872 1.23 0.00668 0.0886 0.94 0.02694 1.01 0.846 1.2 0.0215 0.0886 0.808 0.09243 1.02 0.859 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 112.3 Candidiasis of skin and nails Both 295 970 1 infectious diseases blue 970, 295 243, 76 242, 57 242, 82 243, 80 0.0433 0.0659 0.511 0.2918 1.04 0.918 1.19 -0.269 0.199 0.176 0.7533 0.764 0.518 1.13 0.0725 0.184 0.694 0.1583 1.08 0.749 1.54 0.0296 0.185 0.873 0.05893 1.03 0.716 1.48 PRS_PLINK_2.51188643150958e.06 FALSE 117 Mycoses Both 217 799 1 infectious diseases blue 799, 217 200, 50 200, 51 199, 51 200, 65 0.1 0.0725 0.168 0.7751 1.11 0.959 1.27 -0.0127 0.225 0.955 0.02008 0.987 0.636 1.53 0.0407 0.224 0.856 0.06753 1.04 0.671 1.62 0.216 0.217 0.318 0.4976 1.24 0.812 1.9 PRS_PLINK_2.51188643150958e.06 FALSE 117.1 Histoplasmosis Both 22 110 1 infectious diseases blue 110, 22 28, 5 27, 5 27, 8 28, 4 0.111 0.21 0.598 0.2236 1.12 0.74 1.69 -0.214 0.791 0.786 0.1043 0.807 0.171 3.8 0.225 0.67 0.737 0.1326 1.25 0.337 4.66 -0.296 0.759 0.697 0.157 0.744 0.168 3.29 PRS_PLINK_2.51188643150958e.06 TRUE 117.4 Aspergillosis Both 57 168 1 infectious diseases blue 168, 57 42, 17 42, 14 42, 12 42, 14 -0.161 0.161 0.317 0.499 0.851 0.621 1.17 -0.125 0.453 0.783 0.1063 0.883 0.363 2.15 -0.181 0.454 0.69 0.1613 0.834 0.342 2.03 -0.0604 0.445 0.892 0.04966 0.941 0.394 2.25 PRS_PLINK_2.51188643150958e.06 FALSE 130 Spirochetal infection Both 62 248 1 infectious diseases blue 248, 62 62, 15 62, 22 62, 15 62, 10 -0.107 0.158 0.499 0.3023 0.898 0.659 1.23 0.377 0.394 0.339 0.4694 1.46 0.673 3.16 -0.125 0.433 0.773 0.1116 0.883 0.378 2.06 -0.287 0.447 0.521 0.2829 0.751 0.312 1.8 PRS_PLINK_2.51188643150958e.06 FALSE 130.1 Lyme disease Both 39 168 1 infectious diseases blue 168, 39 42, 12 42, 15 42, 8 42, 4 -0.196 0.176 0.266 0.5758 0.822 0.582 1.16 0.303 0.463 0.513 0.2901 1.35 0.547 3.35 -0.386 0.532 0.468 0.33 0.679 0.239 1.93 -1.2 0.637 0.059 1.229 0.3 0.0861 1.05 PRS_PLINK_2.51188643150958e.06 TRUE 131 Protozoan infection Both 25 81 1 infectious diseases blue 81, 25 21, 8 20, 0 20, 3 20, 14 0.547 0.317 0.0848 1.071 1.73 0.928 3.22 -2.38 1.5 0.112 0.9507 0.0926 0.00492 1.74 -0.519 0.773 0.502 0.2989 0.595 0.131 2.71 0.588 0.634 0.354 0.4511 1.8 0.52 6.24 PRS_PLINK_2.51188643150958e.06 TRUE 132 Infestation (lice, mites) Both 74 274 1 infectious diseases blue 274, 74 69, 22 68, 19 68, 20 69, 13 -0.199 0.141 0.157 0.8044 0.819 0.622 1.08 -0.144 0.366 0.694 0.1585 0.866 0.422 1.78 -0.318 0.367 0.386 0.4138 0.727 0.354 1.49 -0.748 0.408 0.0667 1.176 0.473 0.213 1.05 PRS_PLINK_2.51188643150958e.06 FALSE 134 Helminthiases Both 27 124 1 infectious diseases blue 124, 27 31, 9 31, 6 31, 4 31, 8 -0.021 0.225 0.926 0.03351 0.979 0.63 1.52 -0.176 0.605 0.772 0.1126 0.839 0.256 2.74 -0.786 0.661 0.234 0.6303 0.456 0.125 1.66 -0.0852 0.58 0.883 0.05392 0.918 0.294 2.86 PRS_PLINK_2.51188643150958e.06 TRUE 134.1 Intestinal helminthiases Both 17 83 1 infectious diseases blue 83, 17 21, 4 21, 5 20, 4 21, 4 0.142 0.243 0.56 0.2519 1.15 0.716 1.85 0.123 0.774 0.873 0.05882 1.13 0.248 5.15 0.383 0.944 0.685 0.1642 1.47 0.23 9.33 0.206 0.803 0.797 0.09841 1.23 0.255 5.93 PRS_PLINK_2.51188643150958e.06 TRUE 136 Other infectious and parasitic diseases Both 1096 4941 1 infectious diseases blue 4941, 1096 1235, 286 1235, 252 1235, 273 1235, 285 0.0098 0.0332 0.768 0.1146 1.01 0.946 1.08 -0.119 0.0955 0.211 0.6761 0.887 0.736 1.07 -0.055 0.0938 0.557 0.2538 0.946 0.787 1.14 -0.00491 0.0932 0.958 0.01865 0.995 0.829 1.19 PRS_PLINK_2.51188643150958e.06 FALSE 145 Cancer of mouth Both 166 2403 2 neoplasms darkcyan 2403, 166 600, 41 601, 38 600, 46 601, 41 -0.0188 0.0785 0.811 0.09101 0.981 0.841 1.14 -0.0486 0.229 0.832 0.07972 0.953 0.608 1.49 0.0882 0.22 0.688 0.1623 1.09 0.71 1.68 -0.0393 0.227 0.862 0.06427 0.961 0.616 1.5 PRS_PLINK_2.51188643150958e.06 FALSE 145.1 Cancer of lip Both 8 118 2 neoplasms darkcyan 118, 8 30, 2 29, 1 29, 4 30, 1 -0.0247 0.318 0.938 0.02781 0.976 0.523 1.82 -0.225 0.886 0.8 0.09712 0.799 0.141 4.53 0.387 0.787 0.623 0.2057 1.47 0.315 6.89 -0.379 0.869 0.663 0.1787 0.685 0.125 3.76 PRS_PLINK_2.51188643150958e.06 TRUE 145.2 Cancer of tongue Both 66 1009 2 neoplasms darkcyan 1009, 66 253, 12 252, 16 252, 19 252, 19 0.0453 0.131 0.729 0.137 1.05 0.81 1.35 0.348 0.373 0.35 0.4556 1.42 0.682 2.94 0.443 0.367 0.227 0.6441 1.56 0.759 3.2 0.387 0.369 0.295 0.5301 1.47 0.714 3.03 PRS_PLINK_2.51188643150958e.06 FALSE 145.3 Cancer of major salivary glands Both 49 604 2 neoplasms darkcyan 604, 49 150, 11 151, 10 151, 15 151, 13 0.0971 0.145 0.502 0.2993 1.1 0.83 1.46 0.00187 0.434 0.997 0.001493 1 0.428 2.34 0.184 0.407 0.652 0.186 1.2 0.541 2.67 0.201 0.411 0.625 0.204 1.22 0.547 2.73 PRS_PLINK_2.51188643150958e.06 TRUE 145.4 Cancer of the gums Both 17 281 2 neoplasms darkcyan 281, 17 71, 5 70, 2 70, 5 70, 5 -0.225 0.219 0.305 0.516 0.799 0.52 1.23 -0.392 0.723 0.588 0.2306 0.676 0.164 2.79 0.176 0.636 0.782 0.1069 1.19 0.343 4.15 -0.176 0.635 0.781 0.1071 0.839 0.242 2.91 PRS_PLINK_2.51188643150958e.06 TRUE 145.5 Cancer of the mouth floor Both 28 329 2 neoplasms darkcyan 329, 28 83, 7 82, 9 82, 3 82, 9 -0.387 0.168 0.0211 1.675 0.679 0.489 0.944 0.324 0.503 0.52 0.2836 1.38 0.515 3.71 -0.805 0.628 0.2 0.6996 0.447 0.131 1.53 0.189 0.506 0.709 0.1494 1.21 0.448 3.25 PRS_PLINK_2.51188643150958e.06 TRUE 149 Cancer of larynx, pharynx, nasal cavities Both 154 2154 2 neoplasms darkcyan 2154, 154 538, 38 538, 37 538, 44 539, 35 -0.0187 0.0816 0.819 0.08657 0.982 0.836 1.15 -0.0339 0.237 0.887 0.0523 0.967 0.607 1.54 0.166 0.228 0.465 0.3325 1.18 0.756 1.85 -0.0433 0.239 0.856 0.06744 0.958 0.6 1.53 PRS_PLINK_2.51188643150958e.06 FALSE 149.1 Cancer of oropharynx Both 39 532 2 neoplasms darkcyan 532, 39 133, 8 133, 11 133, 12 133, 8 -0.069 0.163 0.672 0.1728 0.933 0.678 1.28 0.165 0.455 0.717 0.1442 1.18 0.484 2.87 0.341 0.452 0.45 0.347 1.41 0.581 3.41 0.0482 0.474 0.919 0.0367 1.05 0.415 2.66 PRS_PLINK_2.51188643150958e.06 TRUE 149.2 Cancer of nasopharynx Both 18 182 2 neoplasms darkcyan 182, 18 45, 1 45, 6 45, 7 46, 4 0.221 0.301 0.464 0.3337 1.25 0.691 2.25 1.59 0.873 0.068 1.168 4.92 0.889 27.2 1.75 0.91 0.0541 1.267 5.77 0.97 34.4 1.34 0.882 0.128 0.8934 3.83 0.68 21.6 PRS_PLINK_2.51188643150958e.06 TRUE 149.3 Cancer of hypopharynx Both 14 152 2 neoplasms darkcyan 152, 14 38, 6 38, 4 38, 3 38, 1 -0.351 0.229 0.124 0.9053 0.704 0.45 1.1 -0.155 0.687 0.821 0.08561 0.856 0.223 3.29 -0.28 0.718 0.697 0.1567 0.756 0.185 3.09 -1.28 0.884 0.148 0.8296 0.278 0.0492 1.57 PRS_PLINK_2.51188643150958e.06 TRUE 149.4 Cancer of larynx Both 47 625 2 neoplasms darkcyan 625, 47 157, 10 156, 14 156, 12 156, 11 0.0953 0.145 0.512 0.2905 1.1 0.827 1.46 0.496 0.421 0.239 0.6224 1.64 0.72 3.75 0.343 0.46 0.456 0.3414 1.41 0.572 3.47 0.334 0.453 0.46 0.3371 1.4 0.575 3.39 PRS_PLINK_2.51188643150958e.06 TRUE 149.5 Hx of malignant neoplasm of oral cavity and pharynx Both 80 934 2 neoplasms darkcyan 934, 80 234, 18 233, 18 233, 24 234, 20 0.0391 0.12 0.745 0.128 1.04 0.822 1.32 -0.0644 0.349 0.854 0.06872 0.938 0.473 1.86 0.314 0.32 0.327 0.4852 1.37 0.731 2.56 0.104 0.329 0.752 0.1238 1.11 0.582 2.12 PRS_PLINK_2.51188643150958e.06 FALSE 149.9 Cancer of of nasal cavities Both 25 417 2 neoplasms darkcyan 417, 25 105, 8 104, 4 104, 8 104, 5 -0.0596 0.202 0.768 0.1145 0.942 0.634 1.4 -0.696 0.591 0.239 0.6212 0.499 0.157 1.59 0.0878 0.479 0.855 0.06828 1.09 0.427 2.79 -0.444 0.526 0.399 0.3994 0.641 0.229 1.8 PRS_PLINK_2.51188643150958e.06 TRUE 150 Cancer of esophagus Both 79 543 2 neoplasms darkcyan 543, 79 136, 27 136, 23 135, 14 136, 15 -0.199 0.122 0.104 0.9845 0.82 0.645 1.04 -0.243 0.311 0.434 0.3623 0.784 0.427 1.44 -0.629 0.343 0.0667 1.176 0.533 0.272 1.04 -0.543 0.344 0.114 0.9421 0.581 0.296 1.14 PRS_PLINK_2.51188643150958e.06 FALSE 151 Cancer of stomach Both 111 620 2 neoplasms darkcyan 620, 111 155, 34 155, 30 156, 25 154, 21 -0.199 0.0947 0.0359 1.445 0.82 0.681 0.987 -0.144 0.275 0.602 0.2207 0.866 0.505 1.49 -0.284 0.289 0.326 0.4874 0.753 0.428 1.33 -0.478 0.303 0.115 0.9393 0.62 0.342 1.12 PRS_PLINK_2.51188643150958e.06 FALSE 153 Colorectal cancer Both 365 1573 2 neoplasms darkcyan 1573, 365 394, 89 393, 97 393, 86 393, 92 -0.0214 0.0581 0.713 0.1466 0.979 0.873 1.1 0.0854 0.164 0.602 0.2202 1.09 0.79 1.5 -0.0416 0.167 0.804 0.09486 0.959 0.691 1.33 0.0295 0.166 0.86 0.06575 1.03 0.743 1.43 PRS_PLINK_2.51188643150958e.06 FALSE 153.2 Colon cancer Both 294 1258 2 neoplasms darkcyan 1258, 294 315, 68 314, 86 314, 72 315, 68 -0.00453 0.0664 0.946 0.02427 0.995 0.874 1.13 0.249 0.182 0.17 0.77 1.28 0.899 1.83 0.0641 0.187 0.732 0.1355 1.07 0.739 1.54 -0.0124 0.19 0.948 0.02324 0.988 0.681 1.43 PRS_PLINK_2.51188643150958e.06 FALSE 153.3 Malignant neoplasm of rectum, rectosigmoid junction, and anus Both 209 867 2 neoplasms darkcyan 867, 209 217, 44 217, 57 216, 45 217, 62 0.0959 0.0804 0.233 0.6324 1.1 0.94 1.29 0.255 0.225 0.256 0.591 1.29 0.831 2 -0.0347 0.237 0.883 0.05391 0.966 0.607 1.54 0.378 0.225 0.0928 1.032 1.46 0.939 2.27 PRS_PLINK_2.51188643150958e.06 FALSE 155 Cancer of liver and intrahepatic bile duct Both 107 628 2 neoplasms darkcyan 628, 107 157, 28 157, 31 157, 25 157, 23 -0.0941 0.102 0.358 0.4462 0.91 0.745 1.11 0.136 0.284 0.633 0.1988 1.15 0.656 2 -0.0154 0.3 0.959 0.01816 0.985 0.547 1.77 -0.196 0.301 0.515 0.2882 0.822 0.455 1.48 PRS_PLINK_2.51188643150958e.06 FALSE 155.1 Malignant neoplasm of liver, primary Both 79 419 2 neoplasms darkcyan 419, 79 105, 20 105, 24 104, 19 105, 16 -0.0769 0.132 0.559 0.253 0.926 0.716 1.2 0.199 0.331 0.547 0.2619 1.22 0.638 2.33 -0.00514 0.356 0.988 0.005039 0.995 0.496 2 -0.259 0.365 0.479 0.3195 0.772 0.377 1.58 PRS_PLINK_2.51188643150958e.06 FALSE 157 Pancreatic cancer Both 113 655 2 neoplasms darkcyan 655, 113 164, 23 164, 27 163, 32 164, 31 0.195 0.115 0.0889 1.051 1.22 0.971 1.52 0.145 0.302 0.632 0.1993 1.16 0.639 2.09 0.304 0.292 0.298 0.5253 1.35 0.764 2.4 0.363 0.298 0.224 0.65 1.44 0.801 2.58 PRS_PLINK_2.51188643150958e.06 FALSE 158 Neoplasm of unspecified nature of digestive system Both 543 2091 2 neoplasms darkcyan 2091, 543 523, 127 523, 136 522, 140 523, 140 0.0157 0.0473 0.74 0.131 1.02 0.926 1.11 0.0724 0.138 0.6 0.2216 1.08 0.82 1.41 0.101 0.138 0.464 0.3336 1.11 0.845 1.45 0.1 0.138 0.467 0.3311 1.11 0.844 1.45 PRS_PLINK_2.51188643150958e.06 FALSE 159 Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum Both 468 2194 2 neoplasms darkcyan 2194, 468 549, 110 548, 138 548, 101 549, 119 -0.00628 0.0515 0.903 0.04433 0.994 0.898 1.1 0.228 0.141 0.106 0.9751 1.26 0.953 1.66 -0.0807 0.15 0.591 0.2288 0.922 0.687 1.24 0.0706 0.145 0.627 0.2028 1.07 0.807 1.43 PRS_PLINK_2.51188643150958e.06 FALSE 159.2 Malignant neoplasm of small intestine, including duodenum Both 56 274 2 neoplasms darkcyan 274, 56 69, 14 68, 11 68, 18 69, 13 0.0357 0.139 0.797 0.09854 1.04 0.789 1.36 -0.399 0.441 0.366 0.436 0.671 0.283 1.59 0.204 0.4 0.61 0.215 1.23 0.56 2.69 -0.194 0.425 0.648 0.1882 0.824 0.358 1.89 PRS_PLINK_2.51188643150958e.06 FALSE 159.3 Malignant neoplasm of gallbladder and extrahepatic bile ducts Both 28 208 2 neoplasms darkcyan 208, 28 52, 7 52, 8 52, 2 52, 11 -0.0647 0.184 0.725 0.1396 0.937 0.654 1.34 0.0281 0.534 0.958 0.01866 1.03 0.361 2.93 -0.766 0.733 0.296 0.5287 0.465 0.111 1.96 0.568 0.523 0.278 0.5564 1.76 0.633 4.92 PRS_PLINK_2.51188643150958e.06 TRUE 159.4 Malignant neoplasm of retroperitoneum and peritoneum Both 48 351 2 neoplasms darkcyan 351, 48 88, 6 88, 18 87, 9 88, 15 0.304 0.177 0.0855 1.068 1.36 0.958 1.92 0.859 0.472 0.0685 1.165 2.36 0.937 5.95 0.417 0.515 0.418 0.3787 1.52 0.553 4.16 0.77 0.477 0.106 0.973 2.16 0.848 5.5 PRS_PLINK_2.51188643150958e.06 TRUE 164 Cancer of intrathoracic organs Both 35 220 2 neoplasms darkcyan 220, 35 55, 10 55, 10 55, 10 55, 5 -0.102 0.208 0.625 0.2044 0.903 0.601 1.36 -0.0957 0.481 0.842 0.07458 0.909 0.354 2.33 -0.0843 0.493 0.864 0.06339 0.919 0.35 2.41 -0.681 0.567 0.23 0.6392 0.506 0.167 1.54 PRS_PLINK_2.51188643150958e.06 TRUE 165 Cancer within the respiratory system Both 248 2278 2 neoplasms darkcyan 2278, 248 569, 76 569, 55 569, 73 570, 44 -0.0669 0.0654 0.306 0.5141 0.935 0.823 1.06 -0.355 0.186 0.057 1.244 0.702 0.487 1.01 -0.022 0.174 0.899 0.04607 0.978 0.695 1.38 -0.551 0.198 0.00544 2.265 0.577 0.391 0.85 PRS_PLINK_2.51188643150958e.06 FALSE 165.1 Cancer of bronchus; lung Both 208 1849 2 neoplasms darkcyan 1849, 208 463, 69 462, 44 462, 58 462, 37 -0.0837 0.0727 0.25 0.6027 0.92 0.798 1.06 -0.464 0.203 0.022 1.657 0.629 0.423 0.935 -0.169 0.189 0.372 0.429 0.845 0.583 1.22 -0.617 0.213 0.00382 2.418 0.54 0.355 0.82 PRS_PLINK_2.51188643150958e.06 FALSE 170 Cancer of bone and connective tissue Both 259 2987 2 neoplasms darkcyan 2987, 259 747, 60 747, 73 746, 56 747, 70 -0.0477 0.0633 0.451 0.3457 0.953 0.842 1.08 0.191 0.18 0.288 0.5408 1.21 0.851 1.72 -0.0729 0.191 0.703 0.153 0.93 0.639 1.35 0.166 0.182 0.363 0.4402 1.18 0.826 1.69 PRS_PLINK_2.51188643150958e.06 FALSE 170.1 Bone cancer Both 113 1289 2 neoplasms darkcyan 1289, 113 323, 25 322, 32 322, 22 322, 34 -0.0726 0.094 0.44 0.3569 0.93 0.773 1.12 0.259 0.273 0.344 0.4637 1.3 0.758 2.21 -0.0685 0.297 0.818 0.08743 0.934 0.522 1.67 0.278 0.273 0.309 0.5104 1.32 0.773 2.26 PRS_PLINK_2.51188643150958e.06 FALSE 170.2 Cancer of connective tissue Both 179 2075 2 neoplasms darkcyan 2075, 179 519, 38 519, 54 518, 42 519, 45 -0.0247 0.0765 0.747 0.1268 0.976 0.84 1.13 0.338 0.217 0.12 0.9207 1.4 0.916 2.15 0.106 0.229 0.642 0.1924 1.11 0.71 1.74 0.203 0.227 0.372 0.4299 1.22 0.785 1.91 PRS_PLINK_2.51188643150958e.06 FALSE 172 Skin cancer Both 1603 5155 2 neoplasms darkcyan 5155, 1603 1289, 439 1289, 395 1288, 390 1289, 378 -0.0701 0.0298 0.0189 1.723 0.932 0.879 0.989 -0.114 0.0846 0.177 0.7531 0.892 0.756 1.05 -0.122 0.0852 0.152 0.8168 0.885 0.749 1.05 -0.146 0.0855 0.0874 1.058 0.864 0.731 1.02 PRS_PLINK_2.51188643150958e.06 FALSE 172.1 Melanomas of skin, dx or hx Both 1092 4746 2 neoplasms darkcyan 4746, 1092 1187, 296 1186, 263 1186, 267 1187, 265 -0.0471 0.0351 0.179 0.7469 0.954 0.891 1.02 -0.101 0.0985 0.306 0.5139 0.904 0.745 1.1 -0.099 0.0985 0.315 0.5018 0.906 0.747 1.1 -0.114 0.0986 0.246 0.6087 0.892 0.735 1.08 PRS_PLINK_2.51188643150958e.06 FALSE 172.11 Melanomas of skin Both 376 3917 2 neoplasms darkcyan 3917, 376 980, 99 979, 91 979, 97 979, 89 -0.0202 0.0555 0.716 0.1454 0.98 0.879 1.09 -0.0764 0.153 0.617 0.2097 0.926 0.687 1.25 -0.0306 0.15 0.839 0.07625 0.97 0.722 1.3 -0.0969 0.154 0.528 0.277 0.908 0.671 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 172.2 Other non-epithelial cancer of skin Both 1439 4844 2 neoplasms darkcyan 4844, 1439 1211, 401 1211, 350 1211, 344 1211, 343 -0.0764 0.0311 0.014 1.852 0.926 0.872 0.985 -0.138 0.0885 0.12 0.9213 0.871 0.733 1.04 -0.154 0.0892 0.0847 1.072 0.857 0.72 1.02 -0.155 0.0889 0.0818 1.087 0.857 0.72 1.02 PRS_PLINK_2.51188643150958e.06 FALSE 172.21 Basal cell carcinoma Both 885 3931 2 neoplasms darkcyan 3931, 885 983, 216 983, 220 982, 225 983, 223 -0.00389 0.0395 0.922 0.03547 0.996 0.922 1.08 0.0382 0.11 0.728 0.1378 1.04 0.838 1.29 0.0618 0.109 0.572 0.2422 1.06 0.858 1.32 0.0409 0.11 0.709 0.1492 1.04 0.84 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 172.22 Squamous cell carcinoma Both 515 2848 2 neoplasms darkcyan 2848, 515 712, 139 712, 120 712, 127 712, 129 -0.0287 0.05 0.566 0.2469 0.972 0.881 1.07 -0.106 0.138 0.44 0.3564 0.899 0.687 1.18 -0.106 0.137 0.44 0.3566 0.9 0.688 1.18 -0.0547 0.136 0.687 0.1632 0.947 0.726 1.24 PRS_PLINK_2.51188643150958e.06 FALSE 172.3 Carcinoma in situ of skin Both 370 2115 2 neoplasms darkcyan 2115, 370 529, 92 529, 100 528, 93 529, 85 -0.0104 0.0576 0.857 0.06697 0.99 0.884 1.11 0.121 0.159 0.446 0.3504 1.13 0.827 1.54 -0.0211 0.162 0.896 0.0477 0.979 0.713 1.34 -0.0438 0.164 0.789 0.1027 0.957 0.694 1.32 PRS_PLINK_2.51188643150958e.06 FALSE 173 Neoplasm of uncertain behavior of skin Both 600 3179 2 neoplasms darkcyan 3179, 600 795, 167 795, 140 794, 159 795, 134 -0.0348 0.044 0.428 0.3684 0.966 0.886 1.05 -0.18 0.125 0.152 0.8188 0.836 0.654 1.07 -0.0595 0.122 0.625 0.204 0.942 0.742 1.2 -0.214 0.127 0.0921 1.036 0.808 0.63 1.04 PRS_PLINK_2.51188643150958e.06 FALSE 174 Breast cancer Both 616 2508 2 neoplasms darkcyan 2508, 616 627, 162 627, 166 627, 153 627, 135 -0.0506 0.0449 0.259 0.5869 0.951 0.871 1.04 -0.0219 0.127 0.863 0.06389 0.978 0.762 1.26 -0.0829 0.129 0.52 0.2836 0.92 0.715 1.19 -0.203 0.132 0.126 0.8985 0.817 0.63 1.06 PRS_PLINK_2.51188643150958e.06 FALSE 174.1 Breast cancer [female] Female 566 2383 2 neoplasms darkcyan 2383, 566 596, 150 596, 150 595, 142 596, 124 -0.0474 0.0474 0.318 0.4974 0.954 0.869 1.05 -0.0604 0.134 0.651 0.1862 0.941 0.725 1.22 -0.0649 0.134 0.628 0.2019 0.937 0.721 1.22 -0.204 0.138 0.139 0.8562 0.816 0.622 1.07 PRS_PLINK_2.51188643150958e.06 FALSE 174.11 Malignant neoplasm of female breast Female 561 2368 2 neoplasms darkcyan 2368, 561 592, 147 592, 148 592, 142 592, 124 -0.0362 0.048 0.45 0.3466 0.964 0.878 1.06 -0.0594 0.134 0.659 0.1814 0.942 0.724 1.23 -0.046 0.134 0.732 0.1354 0.955 0.734 1.24 -0.184 0.138 0.184 0.7357 0.832 0.634 1.09 PRS_PLINK_2.51188643150958e.06 FALSE 174.3 Neoplasm of uncertain behavior of breast Both 60 364 2 neoplasms darkcyan 364, 60 91, 15 91, 12 91, 15 91, 18 PRS_PLINK_2.51188643150958e.06 FALSE 175 Acquired absence of breast Female 184 1176 2 neoplasms darkcyan 1176, 184 294, 45 294, 46 294, 46 294, 47 0.0187 0.0783 0.812 0.0907 1.02 0.874 1.19 -0.0388 0.228 0.865 0.06298 0.962 0.615 1.5 -0.0369 0.227 0.871 0.06011 0.964 0.618 1.5 0.00966 0.225 0.966 0.01515 1.01 0.65 1.57 PRS_PLINK_2.51188643150958e.06 FALSE 180 Cervical cancer and dysplasia Female 340 1739 2 neoplasms darkcyan 1739, 340 435, 76 435, 96 434, 75 435, 93 0.0695 0.0615 0.258 0.5876 1.07 0.95 1.21 0.256 0.169 0.128 0.8927 1.29 0.929 1.8 0.0248 0.177 0.888 0.05137 1.03 0.725 1.45 0.209 0.17 0.219 0.6591 1.23 0.883 1.72 PRS_PLINK_2.51188643150958e.06 FALSE 180.1 Cervical cancer Female 95 722 2 neoplasms darkcyan 722, 95 181, 18 180, 36 180, 18 181, 23 -0.0263 0.0992 0.791 0.1017 0.974 0.802 1.18 0.661 0.305 0.0305 1.516 1.94 1.06 3.52 0.04 0.351 0.909 0.04127 1.04 0.523 2.07 0.198 0.334 0.553 0.2569 1.22 0.634 2.34 PRS_PLINK_2.51188643150958e.06 FALSE 180.3 Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia] Female 274 1281 2 neoplasms darkcyan 1281, 274 321, 64 320, 75 320, 59 320, 76 0.0927 0.0698 0.184 0.7357 1.1 0.957 1.26 0.159 0.188 0.398 0.3999 1.17 0.811 1.69 -0.0642 0.197 0.745 0.128 0.938 0.637 1.38 0.187 0.187 0.318 0.4976 1.21 0.835 1.74 PRS_PLINK_2.51188643150958e.06 FALSE 182 Malignant neoplasm of uterus Female 131 1238 2 neoplasms darkcyan 1238, 131 310, 28 309, 45 309, 30 310, 28 0.0338 0.0953 0.723 0.1408 1.03 0.858 1.25 0.421 0.252 0.0955 1.02 1.52 0.929 2.5 0.106 0.273 0.699 0.1558 1.11 0.651 1.9 -0.0133 0.283 0.962 0.01664 0.987 0.567 1.72 PRS_PLINK_2.51188643150958e.06 FALSE 184 Cancer of other female genital organs Female 277 2029 2 neoplasms darkcyan 2029, 277 508, 61 507, 77 507, 60 507, 79 -0.00422 0.0624 0.946 0.02405 0.996 0.881 1.13 0.235 0.183 0.198 0.7032 1.26 0.884 1.81 0.0434 0.193 0.822 0.08524 1.04 0.716 1.52 0.279 0.183 0.127 0.8949 1.32 0.923 1.89 PRS_PLINK_2.51188643150958e.06 FALSE 184.1 Malignant neoplasm of ovary and other uterine adnexa Female 114 1014 2 neoplasms darkcyan 1014, 114 254, 34 253, 29 253, 24 254, 27 -0.085 0.0882 0.335 0.4753 0.918 0.773 1.09 -0.134 0.264 0.612 0.2136 0.874 0.521 1.47 -0.264 0.278 0.343 0.4645 0.768 0.446 1.32 -0.163 0.272 0.549 0.2604 0.849 0.498 1.45 PRS_PLINK_2.51188643150958e.06 FALSE 184.11 Malignant neoplasm of ovary Female 74 766 2 neoplasms darkcyan 766, 74 192, 20 191, 21 191, 16 192, 17 -0.104 0.115 0.366 0.4361 0.902 0.72 1.13 0.0748 0.328 0.82 0.08625 1.08 0.566 2.05 -0.121 0.342 0.724 0.14 0.886 0.453 1.73 0.0168 0.344 0.961 0.01729 1.02 0.518 1.99 PRS_PLINK_2.51188643150958e.06 FALSE 184.2 Cancer of other female genital organs (excluding uterus and ovary) Female 164 1096 2 neoplasms darkcyan 1096, 164 274, 32 274, 36 274, 44 274, 52 0.042 0.0816 0.607 0.2168 1.04 0.889 1.22 0.145 0.255 0.568 0.2455 1.16 0.702 1.9 0.394 0.25 0.114 0.9423 1.48 0.909 2.42 0.458 0.242 0.0585 1.233 1.58 0.984 2.54 PRS_PLINK_2.51188643150958e.06 FALSE 185 Cancer of prostate Male 446 1241 2 neoplasms darkcyan 1241, 446 310, 118 310, 115 310, 113 310, 100 -0.0477 0.0605 0.43 0.3662 0.953 0.847 1.07 -0.0131 0.173 0.94 0.02703 0.987 0.703 1.38 -0.0656 0.17 0.7 0.1551 0.936 0.671 1.31 -0.184 0.179 0.305 0.5163 0.832 0.585 1.18 PRS_PLINK_2.51188643150958e.06 FALSE 187 Cancer of other male genital organs Male 65 473 2 neoplasms darkcyan 473, 65 119, 18 118, 12 118, 20 118, 15 0.0186 0.127 0.883 0.05388 1.02 0.795 1.31 -0.446 0.389 0.252 0.5992 0.64 0.299 1.37 0.0881 0.355 0.804 0.09463 1.09 0.544 2.19 -0.191 0.369 0.604 0.2189 0.826 0.4 1.7 PRS_PLINK_2.51188643150958e.06 FALSE 187.1 Malignant neoplasm of unspecified male genital organ Male 20 174 2 neoplasms darkcyan 174, 20 44, 5 43, 1 43, 7 44, 7 0.252 0.237 0.288 0.541 1.29 0.808 2.05 -2.71 1.4 0.0528 1.278 0.0667 0.0043 1.03 0.533 0.656 0.417 0.38 1.7 0.471 6.17 0.739 0.705 0.295 0.5306 2.09 0.526 8.33 PRS_PLINK_2.51188643150958e.06 TRUE 187.2 Malignant neoplasm of testis Male 31 233 2 neoplasms darkcyan 233, 31 59, 10 58, 9 58, 7 58, 5 -0.102 0.179 0.567 0.2465 0.903 0.636 1.28 -0.11 0.505 0.827 0.08232 0.896 0.333 2.41 -0.462 0.529 0.383 0.4169 0.63 0.223 1.78 -0.905 0.597 0.13 0.8866 0.405 0.125 1.3 PRS_PLINK_2.51188643150958e.06 TRUE 187.8 Neoplasm of uncertain behavior of male genital organs Male 14 88 2 neoplasms darkcyan 88, 14 22, 3 22, 3 22, 3 22, 5 0.0993 0.351 0.777 0.1093 1.1 0.555 2.2 -0.0678 0.829 0.935 0.0293 0.934 0.184 4.74 0.308 0.937 0.743 0.1293 1.36 0.217 8.54 0.58 0.799 0.468 0.3299 1.79 0.373 8.56 PRS_PLINK_2.51188643150958e.06 TRUE 189 Cancer of urinary organs (incl. kidney and bladder) Both 603 3792 2 neoplasms darkcyan 3792, 603 948, 146 948, 160 948, 125 948, 171 0.0687 0.0455 0.131 0.8835 1.07 0.98 1.17 0.121 0.124 0.329 0.4825 1.13 0.885 1.44 -0.136 0.132 0.302 0.5203 0.873 0.674 1.13 0.186 0.123 0.13 0.885 1.2 0.946 1.53 PRS_PLINK_2.51188643150958e.06 FALSE 189.1 Cancer of kidney and renal pelvis Both 233 2361 2 neoplasms darkcyan 2361, 233 591, 54 590, 66 590, 51 590, 61 0.0392 0.069 0.57 0.244 1.04 0.908 1.19 0.192 0.191 0.315 0.502 1.21 0.833 1.76 -0.0356 0.202 0.86 0.0654 0.965 0.649 1.43 0.129 0.194 0.506 0.2955 1.14 0.778 1.66 PRS_PLINK_2.51188643150958e.06 FALSE 189.11 Malignant neoplasm of kidney, except pelvis Both 184 2079 2 neoplasms darkcyan 2079, 184 520, 44 520, 45 519, 42 520, 53 0.106 0.0821 0.196 0.7078 1.11 0.947 1.31 0.0477 0.219 0.828 0.08204 1.05 0.682 1.61 -0.0161 0.222 0.942 0.02586 0.984 0.637 1.52 0.233 0.213 0.273 0.5642 1.26 0.832 1.92 PRS_PLINK_2.51188643150958e.06 FALSE 189.12 Malignant neoplasm of renal pelvis Both 47 411 2 neoplasms darkcyan 411, 47 103, 10 103, 10 102, 7 103, 20 0.32 0.181 0.0765 1.116 1.38 0.966 1.96 0.0439 0.441 0.921 0.03592 1.04 0.44 2.48 -0.29 0.473 0.54 0.2676 0.748 0.296 1.89 0.666 0.4 0.0965 1.016 1.95 0.888 4.26 PRS_PLINK_2.51188643150958e.06 TRUE 189.2 Cancer of bladder Both 437 2518 2 neoplasms darkcyan 2518, 437 630, 105 629, 107 629, 91 630, 134 0.114 0.0552 0.0382 1.418 1.12 1.01 1.25 0.0468 0.149 0.753 0.1233 1.05 0.783 1.4 -0.134 0.154 0.386 0.4135 0.875 0.647 1.18 0.262 0.143 0.0666 1.177 1.3 0.982 1.72 PRS_PLINK_2.51188643150958e.06 FALSE 189.21 Malignant neoplasm of bladder Both 397 2327 2 neoplasms darkcyan 2327, 397 582, 93 582, 101 581, 83 582, 120 0.113 0.0577 0.0511 1.292 1.12 0.999 1.25 0.0968 0.155 0.532 0.2738 1.1 0.813 1.49 -0.116 0.163 0.474 0.3239 0.89 0.647 1.22 0.269 0.151 0.0754 1.123 1.31 0.973 1.76 PRS_PLINK_2.51188643150958e.06 FALSE 189.4 Malignant neoplasm of other urinary organs Both 181 1102 2 neoplasms darkcyan 1102, 181 276, 38 275, 44 275, 49 276, 50 0.18 0.092 0.0505 1.296 1.2 1 1.43 0.169 0.237 0.475 0.3229 1.18 0.745 1.88 0.289 0.233 0.216 0.6661 1.33 0.845 2.11 0.305 0.231 0.186 0.7298 1.36 0.863 2.13 PRS_PLINK_2.51188643150958e.06 FALSE 190 Cancer of eye Both 28 239 2 neoplasms darkcyan 239, 28 60, 8 60, 2 59, 11 60, 7 0.0574 0.212 0.787 0.104 1.06 0.698 1.61 -1.17 0.709 0.0975 1.011 0.309 0.0771 1.24 0.471 0.512 0.358 0.4459 1.6 0.587 4.37 -0.0984 0.545 0.857 0.06718 0.906 0.312 2.64 PRS_PLINK_2.51188643150958e.06 TRUE 191 Manlignant and unknown neoplasms of brain and nervous system Both 208 1580 2 neoplasms darkcyan 1580, 208 395, 64 395, 45 395, 54 395, 45 -0.112 0.0696 0.107 0.9702 0.894 0.78 1.02 -0.419 0.209 0.045 1.347 0.658 0.437 0.991 -0.144 0.198 0.466 0.3318 0.866 0.587 1.28 -0.351 0.205 0.0875 1.058 0.704 0.471 1.05 PRS_PLINK_2.51188643150958e.06 FALSE 191.1 Cancer of brain and nervous system Both 125 1006 2 neoplasms darkcyan 1006, 125 252, 35 251, 34 251, 34 252, 22 -0.0838 0.0863 0.332 0.4795 0.92 0.776 1.09 -0.109 0.257 0.672 0.1728 0.897 0.542 1.48 -0.00357 0.256 0.989 0.00485 0.996 0.603 1.65 -0.522 0.284 0.0657 1.182 0.593 0.34 1.03 PRS_PLINK_2.51188643150958e.06 FALSE 191.11 Cancer of brain Both 104 843 2 neoplasms darkcyan 843, 104 211, 28 211, 29 210, 27 211, 20 -0.0873 0.103 0.397 0.4011 0.916 0.749 1.12 -0.0835 0.284 0.769 0.114 0.92 0.527 1.61 0.00926 0.286 0.974 0.01138 1.01 0.577 1.77 -0.411 0.306 0.179 0.748 0.663 0.364 1.21 PRS_PLINK_2.51188643150958e.06 FALSE 193 Thyroid cancer Both 148 1524 2 neoplasms darkcyan 1524, 148 381, 31 381, 34 381, 38 381, 45 0.138 0.0912 0.131 0.8833 1.15 0.96 1.37 0.0884 0.259 0.733 0.1351 1.09 0.658 1.81 0.256 0.253 0.312 0.5058 1.29 0.787 2.12 0.364 0.243 0.135 0.8706 1.44 0.893 2.32 PRS_PLINK_2.51188643150958e.06 FALSE 194 Cancer of other endocrine glands Both 140 990 2 neoplasms darkcyan 990, 140 248, 41 247, 31 247, 30 248, 38 -0.0166 0.0942 0.86 0.06555 0.984 0.818 1.18 -0.342 0.253 0.177 0.7518 0.71 0.432 1.17 -0.298 0.254 0.241 0.6184 0.743 0.452 1.22 -0.095 0.24 0.693 0.1594 0.909 0.568 1.46 PRS_PLINK_2.51188643150958e.06 FALSE 195 Cancer, suspected or other Both 3149 3590 2 neoplasms darkcyan 3590, 3149 898, 791 897, 859 897, 764 898, 734 -0.0172 0.0265 0.517 0.2867 0.983 0.933 1.04 0.0891 0.0741 0.229 0.6399 1.09 0.945 1.26 -0.0505 0.0754 0.503 0.2982 0.951 0.82 1.1 -0.0643 0.076 0.398 0.4004 0.938 0.808 1.09 PRS_PLINK_2.51188643150958e.06 FALSE 195.1 Malignant neoplasm, other Both 3101 3586 2 neoplasms darkcyan 3586, 3101 897, 780 896, 847 896, 749 897, 724 -0.019 0.0266 0.475 0.3231 0.981 0.931 1.03 0.0902 0.0744 0.226 0.6466 1.09 0.946 1.27 -0.0592 0.0758 0.435 0.3613 0.943 0.812 1.09 -0.0632 0.0763 0.408 0.3896 0.939 0.808 1.09 PRS_PLINK_2.51188643150958e.06 FALSE 195.3 Malignant neoplasm of head, face, and neck Both 156 1304 2 neoplasms darkcyan 1304, 156 326, 33 326, 37 326, 44 326, 42 0.0561 0.0897 0.531 0.2746 1.06 0.887 1.26 0.131 0.255 0.608 0.2159 1.14 0.692 1.88 0.257 0.241 0.287 0.542 1.29 0.806 2.07 0.201 0.246 0.413 0.3836 1.22 0.755 1.98 PRS_PLINK_2.51188643150958e.06 FALSE 196 Radiotherapy Both 526 2484 2 neoplasms darkcyan 2484, 526 621, 129 621, 134 621, 144 621, 119 -0.00482 0.0488 0.921 0.03558 0.995 0.904 1.1 0.0514 0.14 0.713 0.1469 1.05 0.801 1.38 0.12 0.137 0.384 0.416 1.13 0.861 1.48 -0.0657 0.143 0.645 0.1902 0.936 0.708 1.24 PRS_PLINK_2.51188643150958e.06 FALSE 197 Chemotherapy Both 1267 3295 2 neoplasms darkcyan 3295, 1267 824, 315 824, 335 823, 318 824, 299 0.0117 0.0346 0.736 0.1329 1.01 0.945 1.08 0.0793 0.0962 0.41 0.3873 1.08 0.896 1.31 0.0202 0.0969 0.835 0.07836 1.02 0.844 1.23 -0.0491 0.0978 0.616 0.2108 0.952 0.786 1.15 PRS_PLINK_2.51188643150958e.06 FALSE 198 Secondary malignant neoplasm Both 961 3244 2 neoplasms darkcyan 3244, 961 811, 229 811, 254 811, 264 811, 214 0.0121 0.0394 0.758 0.1203 1.01 0.937 1.09 0.139 0.111 0.21 0.6778 1.15 0.925 1.43 0.146 0.11 0.183 0.7376 1.16 0.933 1.43 -0.0606 0.113 0.591 0.2282 0.941 0.754 1.17 PRS_PLINK_2.51188643150958e.06 FALSE 198.1 Secondary malignancy of lymph nodes Both 534 2942 2 neoplasms darkcyan 2942, 534 736, 129 735, 142 735, 155 736, 108 -0.0276 0.0477 0.562 0.2499 0.973 0.886 1.07 0.0837 0.137 0.54 0.2673 1.09 0.832 1.42 0.186 0.133 0.164 0.7863 1.2 0.927 1.56 -0.204 0.144 0.155 0.8099 0.815 0.615 1.08 PRS_PLINK_2.51188643150958e.06 FALSE 198.2 Secondary malignancy of respiratory organs Both 208 1427 2 neoplasms darkcyan 1427, 208 357, 49 357, 53 356, 61 357, 45 0.0655 0.0773 0.397 0.4016 1.07 0.918 1.24 0.104 0.211 0.621 0.2069 1.11 0.734 1.68 0.199 0.206 0.334 0.4762 1.22 0.815 1.83 -0.124 0.221 0.577 0.2391 0.884 0.573 1.36 PRS_PLINK_2.51188643150958e.06 FALSE 198.3 Secondary malignant neoplasm of digestive systems Both 187 1222 2 neoplasms darkcyan 1222, 187 306, 43 305, 50 305, 58 306, 36 0.0539 0.0833 0.518 0.2858 1.06 0.896 1.24 0.121 0.224 0.59 0.229 1.13 0.727 1.75 0.281 0.216 0.194 0.7121 1.32 0.867 2.02 -0.209 0.239 0.382 0.4183 0.811 0.508 1.3 PRS_PLINK_2.51188643150958e.06 FALSE 198.4 Secondary malignant neoplasm of liver Both 159 1075 2 neoplasms darkcyan 1075, 159 269, 36 269, 48 268, 41 269, 34 0.00943 0.084 0.911 0.04065 1.01 0.856 1.19 0.303 0.238 0.204 0.6912 1.35 0.849 2.16 0.163 0.242 0.501 0.3002 1.18 0.733 1.89 -0.0519 0.253 0.838 0.07697 0.949 0.578 1.56 PRS_PLINK_2.51188643150958e.06 FALSE 198.5 Secondary malignancy of brain/spine Both 125 898 2 neoplasms darkcyan 898, 125 225, 28 224, 35 224, 34 225, 28 -0.0238 0.092 0.795 0.09937 0.976 0.815 1.17 0.232 0.271 0.392 0.4067 1.26 0.742 2.14 0.161 0.273 0.556 0.2548 1.17 0.688 2.01 -0.018 0.283 0.949 0.02259 0.982 0.564 1.71 PRS_PLINK_2.51188643150958e.06 FALSE 198.6 Secondary malignancy of bone Both 208 1147 2 neoplasms darkcyan 1147, 208 287, 55 287, 58 286, 60 287, 35 -0.0612 0.0709 0.388 0.4108 0.941 0.819 1.08 0.124 0.209 0.552 0.2582 1.13 0.752 1.7 0.148 0.209 0.477 0.3212 1.16 0.771 1.75 -0.406 0.235 0.0841 1.075 0.667 0.421 1.06 PRS_PLINK_2.51188643150958e.06 FALSE 198.7 Secondary malignant neoplasm of skin Both 78 452 2 neoplasms darkcyan 452, 78 113, 23 113, 19 113, 20 113, 16 -0.0668 0.121 0.58 0.2369 0.935 0.739 1.18 -0.213 0.347 0.539 0.2685 0.808 0.409 1.6 -0.133 0.339 0.695 0.1582 0.876 0.451 1.7 -0.317 0.355 0.372 0.4297 0.728 0.363 1.46 PRS_PLINK_2.51188643150958e.06 FALSE 199 Neoplasm of uncertain behavior Both 1360 3539 2 neoplasms darkcyan 3539, 1360 885, 337 885, 356 884, 340 885, 326 -0.0054 0.0332 0.871 0.06007 0.995 0.932 1.06 0.0642 0.0947 0.498 0.3026 1.07 0.886 1.28 0.00654 0.0949 0.945 0.02454 1.01 0.836 1.21 -0.0211 0.0964 0.827 0.08263 0.979 0.81 1.18 PRS_PLINK_2.51188643150958e.06 FALSE 199.4 Neurofibromatosis Both 14 121 2 neoplasms darkcyan 121, 14 31, 1 30, 3 30, 2 30, 8 0.66 0.397 0.0965 1.015 1.94 0.888 4.22 1.42 1.06 0.179 0.7467 4.13 0.521 32.7 0.386 0.929 0.677 0.1691 1.47 0.238 9.08 1.25 0.861 0.146 0.8351 3.49 0.646 18.9 PRS_PLINK_2.51188643150958e.06 TRUE 200 Myeloproliferative disease Both 491 1816 2 neoplasms darkcyan 1816, 491 454, 114 454, 138 454, 124 454, 115 -0.00285 0.0527 0.957 0.01916 0.997 0.899 1.11 0.201 0.144 0.164 0.7855 1.22 0.921 1.62 0.0664 0.148 0.655 0.184 1.07 0.799 1.43 -0.04 0.151 0.791 0.1016 0.961 0.715 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 200.1 Polycythemia vera Both 85 335 2 neoplasms darkcyan 335, 85 84, 12 84, 20 83, 28 84, 25 0.33 0.149 0.0268 1.572 1.39 1.04 1.86 0.398 0.417 0.34 0.4689 1.49 0.658 3.37 0.9 0.399 0.0241 1.619 2.46 1.13 5.37 0.585 0.385 0.129 0.8898 1.79 0.844 3.82 PRS_PLINK_2.51188643150958e.06 FALSE 201 Hodgkin's disease Both 46 251 2 neoplasms darkcyan 251, 46 63, 11 63, 11 62, 15 63, 9 -0.0243 0.159 0.879 0.05625 0.976 0.715 1.33 -0.027 0.455 0.953 0.02108 0.973 0.399 2.37 0.454 0.445 0.308 0.5117 1.57 0.658 3.77 -0.365 0.488 0.454 0.3426 0.694 0.266 1.81 PRS_PLINK_2.51188643150958e.06 TRUE 202 Cancer of other lymphoid, histiocytic tissue Both 428 2586 2 neoplasms darkcyan 2586, 428 647, 107 646, 127 646, 103 647, 90 -0.0254 0.0519 0.624 0.2047 0.975 0.881 1.08 0.162 0.143 0.255 0.5931 1.18 0.889 1.56 -0.036 0.15 0.81 0.09128 0.965 0.719 1.29 -0.194 0.154 0.209 0.6805 0.824 0.609 1.11 PRS_PLINK_2.51188643150958e.06 FALSE 202.2 Non-Hodgkins lymphoma Both 369 2211 2 neoplasms darkcyan 2211, 369 553, 89 553, 109 552, 95 553, 76 -0.0041 0.0568 0.942 0.02575 0.996 0.891 1.11 0.2 0.155 0.198 0.704 1.22 0.901 1.66 0.0991 0.161 0.538 0.2694 1.1 0.806 1.51 -0.177 0.168 0.292 0.5352 0.838 0.603 1.16 PRS_PLINK_2.51188643150958e.06 FALSE 202.21 Nodular lymphoma Both 184 1170 2 neoplasms darkcyan 1170, 184 293, 40 292, 65 292, 47 293, 32 -0.0521 0.0775 0.501 0.2998 0.949 0.815 1.11 0.531 0.221 0.0161 1.794 1.7 1.1 2.62 0.178 0.233 0.445 0.3519 1.2 0.756 1.89 -0.239 0.252 0.342 0.4654 0.788 0.481 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 202.22 Reticulosarcoma Both 59 273 2 neoplasms darkcyan 273, 59 69, 12 68, 12 68, 13 68, 22 0.116 0.164 0.481 0.3176 1.12 0.814 1.55 0.0628 0.434 0.885 0.05305 1.06 0.455 2.49 -0.189 0.447 0.672 0.1729 0.827 0.345 1.99 0.446 0.41 0.276 0.5591 1.56 0.7 3.49 PRS_PLINK_2.51188643150958e.06 FALSE 202.24 Large cell lymphoma Both 55 256 2 neoplasms darkcyan 256, 55 64, 13 64, 11 64, 15 64, 16 -0.0647 0.163 0.692 0.1599 0.937 0.68 1.29 -0.239 0.464 0.606 0.2174 0.787 0.317 1.96 -0.213 0.448 0.635 0.1971 0.808 0.336 1.95 -0.143 0.447 0.749 0.1256 0.867 0.361 2.08 PRS_PLINK_2.51188643150958e.06 FALSE 204 Leukemia Both 278 1182 2 neoplasms darkcyan 1182, 278 296, 69 295, 63 295, 69 296, 77 -0.00296 0.0664 0.964 0.01573 0.997 0.875 1.14 -0.0784 0.195 0.687 0.1628 0.925 0.631 1.35 0.00727 0.191 0.97 0.0134 1.01 0.693 1.46 0.084 0.188 0.656 0.1832 1.09 0.752 1.57 PRS_PLINK_2.51188643150958e.06 FALSE 204.1 Lymphoid leukemia Both 77 406 2 neoplasms darkcyan 406, 77 102, 19 101, 15 101, 20 102, 23 0.199 0.139 0.152 0.8193 1.22 0.929 1.6 -0.248 0.378 0.511 0.2917 0.78 0.372 1.64 -0.0452 0.358 0.9 0.04589 0.956 0.474 1.93 0.274 0.344 0.426 0.3709 1.31 0.67 2.58 PRS_PLINK_2.51188643150958e.06 FALSE 204.11 Lymphoid leukemia, acute Both 33 106 2 neoplasms darkcyan 106, 33 27, 7 26, 7 26, 9 27, 10 0.228 0.21 0.279 0.5536 1.26 0.831 1.9 -0.0214 0.637 0.973 0.01177 0.979 0.281 3.41 0.199 0.601 0.74 0.1307 1.22 0.376 3.97 0.576 0.612 0.346 0.4605 1.78 0.536 5.9 PRS_PLINK_2.51188643150958e.06 TRUE 204.12 Lymphoid leukemia, chronic Both 52 295 2 neoplasms darkcyan 295, 52 74, 14 74, 7 73, 12 74, 19 0.203 0.169 0.23 0.6384 1.22 0.88 1.7 -0.707 0.482 0.143 0.8451 0.493 0.192 1.27 -0.239 0.441 0.588 0.2309 0.787 0.331 1.87 0.37 0.4 0.356 0.4491 1.45 0.661 3.17 PRS_PLINK_2.51188643150958e.06 FALSE 204.2 Myeloid leukemia Both 117 466 2 neoplasms darkcyan 466, 117 117, 29 116, 28 116, 31 117, 29 -0.0293 0.0986 0.766 0.1156 0.971 0.801 1.18 -0.0126 0.298 0.966 0.01492 0.987 0.551 1.77 0.0297 0.291 0.919 0.03679 1.03 0.582 1.82 -0.0252 0.295 0.932 0.03064 0.975 0.547 1.74 PRS_PLINK_2.51188643150958e.06 FALSE 204.21 Myeloid leukemia, acute Both 63 267 2 neoplasms darkcyan 267, 63 67, 18 67, 15 66, 13 67, 17 -0.0735 0.131 0.576 0.2399 0.929 0.718 1.2 -0.107 0.394 0.786 0.1046 0.898 0.415 1.95 -0.456 0.41 0.267 0.5737 0.634 0.284 1.42 -0.0715 0.391 0.855 0.06811 0.931 0.433 2 PRS_PLINK_2.51188643150958e.06 FALSE 204.22 Myeloid leukemia, chronic Both 24 113 2 neoplasms darkcyan 113, 24 29, 6 28, 4 28, 9 28, 5 -0.141 0.228 0.536 0.2711 0.869 0.556 1.36 0.0427 0.702 0.952 0.02157 1.04 0.264 4.13 0.126 0.604 0.835 0.07846 1.13 0.347 3.71 -0.205 0.672 0.76 0.1193 0.814 0.218 3.04 PRS_PLINK_2.51188643150958e.06 TRUE 204.4 Multiple myeloma Both 107 386 2 neoplasms darkcyan 386, 107 97, 22 96, 27 96, 33 97, 25 -0.0171 0.107 0.873 0.05887 0.983 0.797 1.21 0.282 0.335 0.401 0.3972 1.33 0.687 2.56 0.434 0.315 0.169 0.7728 1.54 0.832 2.86 0.0376 0.328 0.909 0.04151 1.04 0.546 1.97 PRS_PLINK_2.51188643150958e.06 FALSE 208 Benign neoplasm of colon Both 3579 3746 2 neoplasms darkcyan 3746, 3579 937, 849 936, 916 936, 889 937, 924 0.0339 0.0238 0.155 0.8102 1.03 0.987 1.08 0.0729 0.0682 0.285 0.5451 1.08 0.941 1.23 0.0476 0.0679 0.483 0.3162 1.05 0.918 1.2 0.101 0.0676 0.134 0.8741 1.11 0.969 1.26 PRS_PLINK_2.51188643150958e.06 FALSE 209 Neuroendocrine tumors Both 65 427 2 neoplasms darkcyan 427, 65 107, 13 107, 23 106, 12 107, 16 0.0448 0.119 0.707 0.1504 1.05 0.828 1.32 0.523 0.368 0.155 0.8095 1.69 0.82 3.47 0.0218 0.417 0.958 0.01849 1.02 0.451 2.31 0.189 0.393 0.63 0.2006 1.21 0.56 2.61 PRS_PLINK_2.51188643150958e.06 FALSE 210 Benign neoplasm of lip, oral cavity, and pharynx Both 290 2915 2 neoplasms darkcyan 2915, 290 729, 61 729, 76 728, 76 729, 77 0.0523 0.0647 0.419 0.378 1.05 0.928 1.2 0.217 0.179 0.224 0.6502 1.24 0.876 1.76 0.199 0.18 0.268 0.5716 1.22 0.858 1.74 0.236 0.179 0.186 0.7312 1.27 0.893 1.8 PRS_PLINK_2.51188643150958e.06 FALSE 211 Benign neoplasm of other parts of digestive system Both 2984 3997 2 neoplasms darkcyan 3997, 2984 1000, 710 999, 732 999, 750 999, 791 0.0228 0.0246 0.354 0.4514 1.02 0.975 1.07 0.0339 0.0699 0.627 0.2024 1.03 0.902 1.19 0.0626 0.0698 0.37 0.4317 1.06 0.928 1.22 0.105 0.0694 0.13 0.8856 1.11 0.969 1.27 PRS_PLINK_2.51188643150958e.06 FALSE 212 Benign neoplasm of respiratory and intrathoracic organs Both 356 2850 2 neoplasms darkcyan 2850, 356 712, 94 712, 78 712, 96 713, 88 0.00133 0.0569 0.981 0.008181 1 0.896 1.12 -0.165 0.162 0.306 0.5139 0.848 0.617 1.16 0.0301 0.154 0.845 0.07301 1.03 0.762 1.39 -0.0706 0.158 0.655 0.1838 0.932 0.684 1.27 PRS_PLINK_2.51188643150958e.06 FALSE 213 Benign neoplasm of bone and articular cartilage Both 329 1152 2 neoplasms darkcyan 1152, 329 288, 60 288, 90 288, 86 288, 93 0.17 0.0658 0.01 1.999 1.18 1.04 1.35 0.455 0.189 0.0161 1.793 1.58 1.09 2.29 0.394 0.19 0.038 1.42 1.48 1.02 2.15 0.447 0.186 0.0162 1.79 1.56 1.09 2.25 PRS_PLINK_2.51188643150958e.06 FALSE 214 Lipoma Both 423 2295 2 neoplasms darkcyan 2295, 423 573, 109 574, 116 573, 98 574, 100 0.0058 0.0529 0.913 0.03971 1.01 0.907 1.12 0.0631 0.146 0.666 0.1764 1.07 0.8 1.42 -0.0858 0.152 0.573 0.2421 0.918 0.681 1.24 -0.0929 0.151 0.538 0.2692 0.911 0.678 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 214.1 Lipoma of skin and subcutaneous tissue Both 256 1424 2 neoplasms darkcyan 1424, 256 356, 71 356, 74 356, 56 356, 55 -0.0667 0.0674 0.322 0.4916 0.935 0.82 1.07 0.019 0.182 0.917 0.03776 1.02 0.714 1.46 -0.224 0.194 0.249 0.6033 0.8 0.546 1.17 -0.305 0.195 0.117 0.9314 0.737 0.503 1.08 PRS_PLINK_2.51188643150958e.06 FALSE 215 Other benign neoplasm of connective and other soft tissue Both 1017 5980 2 neoplasms darkcyan 5980, 1017 1494, 242 1495, 269 1495, 262 1495, 244 0.000244 0.034 0.994 0.002497 1 0.936 1.07 0.108 0.096 0.26 0.5856 1.11 0.923 1.34 0.081 0.0965 0.402 0.3963 1.08 0.897 1.31 0.00992 0.0979 0.919 0.03652 1.01 0.834 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 216 Benign neoplasm of skin Both 3054 4313 2 neoplasms darkcyan 4313, 3054 1078, 713 1078, 762 1078, 767 1078, 812 0.0468 0.0241 0.0522 1.282 1.05 1 1.1 0.0681 0.0689 0.323 0.4911 1.07 0.935 1.23 0.0812 0.0684 0.235 0.6283 1.08 0.948 1.24 0.153 0.0681 0.0247 1.608 1.17 1.02 1.33 PRS_PLINK_2.51188643150958e.06 FALSE 216.1 Screening for malignant neoplasms of the skin Both 63 231 2 neoplasms darkcyan 231, 63 58, 11 58, 12 57, 19 58, 21 0.301 0.158 0.0574 1.241 1.35 0.991 1.84 0.226 0.481 0.637 0.1956 1.25 0.489 3.22 0.485 0.424 0.252 0.5983 1.62 0.708 3.73 0.451 0.424 0.288 0.5413 1.57 0.684 3.61 PRS_PLINK_2.51188643150958e.06 FALSE 217 Vascular hamartomas and non-neoplastic nevi Both 539 2409 2 neoplasms darkcyan 2409, 539 602, 125 602, 137 602, 122 602, 155 0.0306 0.0473 0.518 0.2858 1.03 0.94 1.13 0.104 0.138 0.448 0.3488 1.11 0.848 1.45 -0.0203 0.14 0.885 0.05325 0.98 0.745 1.29 0.211 0.134 0.114 0.9439 1.24 0.951 1.61 PRS_PLINK_2.51188643150958e.06 FALSE 217.1 Nevus, non-neoplastic Both 529 2299 2 neoplasms darkcyan 2299, 529 574, 124 575, 130 574, 123 575, 152 0.032 0.048 0.504 0.2972 1.03 0.94 1.13 0.064 0.14 0.647 0.1891 1.07 0.81 1.4 -0.00776 0.141 0.956 0.01953 0.992 0.753 1.31 0.192 0.135 0.155 0.8103 1.21 0.93 1.58 PRS_PLINK_2.51188643150958e.06 FALSE 218 Benign neoplasm of uterus Female 1157 2428 2 neoplasms darkcyan 2428, 1157 607, 249 607, 298 607, 274 607, 336 0.0996 0.0373 0.00763 2.117 1.1 1.03 1.19 0.197 0.104 0.059 1.229 1.22 0.993 1.49 0.108 0.106 0.307 0.513 1.11 0.906 1.37 0.308 0.102 0.0026 2.586 1.36 1.11 1.66 PRS_PLINK_2.51188643150958e.06 FALSE 218.1 Uterine leiomyoma Female 502 2323 2 neoplasms darkcyan 2323, 502 581, 113 581, 130 580, 109 581, 150 0.098 0.0514 0.0565 1.248 1.1 0.997 1.22 0.198 0.143 0.166 0.7804 1.22 0.921 1.61 -0.0076 0.148 0.959 0.0182 0.992 0.743 1.33 0.314 0.139 0.0243 1.614 1.37 1.04 1.8 PRS_PLINK_2.51188643150958e.06 FALSE 218.2 Other benign neoplasm of uterus Female 907 2384 2 neoplasms darkcyan 2384, 907 596, 189 596, 234 596, 223 596, 261 0.104 0.0411 0.0118 1.927 1.11 1.02 1.2 0.22 0.115 0.0555 1.256 1.25 0.995 1.56 0.192 0.116 0.098 1.009 1.21 0.965 1.52 0.324 0.113 0.00423 2.374 1.38 1.11 1.73 PRS_PLINK_2.51188643150958e.06 FALSE 220 Benign neoplasm of ovary Female 190 1262 2 neoplasms darkcyan 1262, 190 316, 37 315, 58 315, 50 316, 45 0.00385 0.0782 0.961 0.01738 1 0.861 1.17 0.459 0.224 0.0405 1.393 1.58 1.02 2.45 0.33 0.23 0.152 0.8188 1.39 0.886 2.18 0.196 0.235 0.405 0.393 1.22 0.767 1.93 PRS_PLINK_2.51188643150958e.06 FALSE 221 Benign neoplasm of other female genital organs Female 410 2032 2 neoplasms darkcyan 2032, 410 508, 94 508, 104 508, 110 508, 102 0.0718 0.0561 0.2 0.6981 1.07 0.963 1.2 0.132 0.156 0.399 0.3995 1.14 0.84 1.55 0.201 0.155 0.195 0.7109 1.22 0.902 1.66 0.0732 0.157 0.642 0.1927 1.08 0.79 1.46 PRS_PLINK_2.51188643150958e.06 FALSE 222 Benign neoplasm of male genital organs Male 264 1594 2 neoplasms darkcyan 1594, 264 398, 78 398, 62 398, 60 399, 64 -0.0586 0.0647 0.365 0.4375 0.943 0.831 1.07 -0.196 0.184 0.288 0.5413 0.822 0.573 1.18 -0.266 0.186 0.153 0.816 0.766 0.532 1.1 -0.167 0.183 0.361 0.4427 0.846 0.591 1.21 PRS_PLINK_2.51188643150958e.06 FALSE 223 Benign neoplasm of kidney and other urinary organs Both 378 1020 2 neoplasms darkcyan 1020, 378 255, 85 255, 90 255, 90 255, 113 0.0968 0.0595 0.104 0.9847 1.1 0.98 1.24 0.0549 0.179 0.76 0.1195 1.06 0.743 1.5 0.0889 0.178 0.617 0.2097 1.09 0.771 1.55 0.276 0.173 0.11 0.9571 1.32 0.939 1.85 PRS_PLINK_2.51188643150958e.06 FALSE 224 Benign neoplasm of eye Both 245 1268 2 neoplasms darkcyan 1268, 245 317, 63 317, 55 317, 61 317, 66 0.0287 0.0737 0.697 0.1569 1.03 0.891 1.19 -0.0978 0.201 0.626 0.2033 0.907 0.612 1.34 0.0399 0.199 0.841 0.07516 1.04 0.705 1.54 0.0905 0.197 0.646 0.1901 1.09 0.744 1.61 PRS_PLINK_2.51188643150958e.06 FALSE 224.1 Benign neoplasm of eye, uveal Both 223 1123 2 neoplasms darkcyan 1123, 223 281, 57 281, 51 280, 53 281, 62 0.0697 0.0784 0.374 0.4269 1.07 0.919 1.25 -0.0749 0.21 0.721 0.1418 0.928 0.615 1.4 0.00754 0.211 0.972 0.01253 1.01 0.666 1.53 0.112 0.205 0.585 0.2328 1.12 0.748 1.67 PRS_PLINK_2.51188643150958e.06 FALSE 225 Benign neoplasm of brain and other parts of nervous system Both 257 1874 2 neoplasms darkcyan 1874, 257 469, 77 468, 51 468, 66 469, 63 -0.0179 0.0658 0.786 0.1048 0.982 0.863 1.12 -0.407 0.192 0.0342 1.466 0.666 0.457 0.97 -0.159 0.182 0.382 0.4174 0.853 0.597 1.22 -0.206 0.183 0.26 0.5849 0.813 0.568 1.17 PRS_PLINK_2.51188643150958e.06 FALSE 225.1 Benign neoplasm of brain, cranial nerves, meninges Both 173 1449 2 neoplasms darkcyan 1449, 173 363, 48 362, 32 362, 52 362, 41 0.0184 0.0834 0.825 0.0834 1.02 0.865 1.2 -0.407 0.239 0.088 1.055 0.666 0.417 1.06 0.0792 0.216 0.713 0.1467 1.08 0.709 1.65 -0.139 0.227 0.54 0.2675 0.87 0.558 1.36 PRS_PLINK_2.51188643150958e.06 FALSE 225.2 Benign neoplasm of spinal cord, meninges Both 92 445 2 neoplasms darkcyan 445, 92 112, 30 111, 19 111, 18 111, 25 -0.0385 0.106 0.716 0.1451 0.962 0.782 1.18 -0.285 0.321 0.375 0.4264 0.752 0.401 1.41 -0.541 0.335 0.106 0.9745 0.582 0.302 1.12 -0.228 0.314 0.467 0.3306 0.796 0.43 1.47 PRS_PLINK_2.51188643150958e.06 FALSE 226 Benign neoplasm of thyroid glands Both 254 2291 2 neoplasms darkcyan 2291, 254 573, 62 573, 58 572, 63 573, 71 0.037 0.067 0.581 0.2361 1.04 0.91 1.18 -0.0667 0.191 0.727 0.1383 0.935 0.643 1.36 0.021 0.186 0.91 0.04094 1.02 0.709 1.47 0.148 0.183 0.418 0.3791 1.16 0.81 1.66 PRS_PLINK_2.51188643150958e.06 FALSE 227 Benign neoplasm of other endocrine glands and related structures Both 306 2826 2 neoplasms darkcyan 2826, 306 707, 87 706, 74 706, 61 707, 84 -0.0117 0.0594 0.844 0.07355 0.988 0.88 1.11 -0.127 0.167 0.447 0.3496 0.881 0.635 1.22 -0.337 0.175 0.0534 1.272 0.714 0.507 1 -0.0226 0.162 0.889 0.05108 0.978 0.712 1.34 PRS_PLINK_2.51188643150958e.06 FALSE 227.1 Benign neoplasm of adrenal gland Both 125 866 2 neoplasms darkcyan 866, 125 216, 30 216, 36 216, 26 217, 33 0.0568 0.0954 0.552 0.2582 1.06 0.878 1.28 0.154 0.264 0.559 0.2525 1.17 0.696 1.96 -0.143 0.279 0.609 0.2156 0.867 0.501 1.5 0.16 0.269 0.553 0.257 1.17 0.692 1.99 PRS_PLINK_2.51188643150958e.06 FALSE 227.2 Benign neoplasm of parathyroid gland Both 122 1280 2 neoplasms darkcyan 1280, 122 320, 28 320, 29 320, 23 320, 42 0.0303 0.0977 0.757 0.1212 1.03 0.851 1.25 0.0574 0.271 0.832 0.07975 1.06 0.623 1.8 -0.172 0.284 0.546 0.2628 0.842 0.482 1.47 0.443 0.254 0.0816 1.088 1.56 0.946 2.56 PRS_PLINK_2.51188643150958e.06 FALSE 227.3 Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch) Both 62 704 2 neoplasms darkcyan 704, 62 176, 24 176, 16 176, 12 176, 10 -0.242 0.118 0.0407 1.391 0.785 0.623 0.99 -0.371 0.332 0.264 0.5784 0.69 0.36 1.32 -0.664 0.359 0.0645 1.19 0.515 0.255 1.04 -0.892 0.389 0.0217 1.664 0.41 0.191 0.877 PRS_PLINK_2.51188643150958e.06 FALSE 228 Hemangioma and lymphangioma, any site Both 685 3606 2 neoplasms darkcyan 3606, 685 901, 154 901, 162 901, 176 902, 193 0.0455 0.0422 0.281 0.5518 1.05 0.963 1.14 0.0608 0.123 0.62 0.2076 1.06 0.836 1.35 0.132 0.12 0.272 0.5648 1.14 0.901 1.44 0.225 0.118 0.057 1.245 1.25 0.993 1.58 PRS_PLINK_2.51188643150958e.06 FALSE 228.1 Hemangioma of skin and subcutaneous tissue Both 446 2390 2 neoplasms darkcyan 2390, 446 597, 97 597, 109 597, 116 598, 124 0.0507 0.0527 0.336 0.4737 1.05 0.949 1.17 0.121 0.151 0.425 0.3713 1.13 0.839 1.52 0.182 0.149 0.222 0.6533 1.2 0.896 1.61 0.249 0.147 0.091 1.041 1.28 0.961 1.71 PRS_PLINK_2.51188643150958e.06 FALSE 229 Benign neoplasm of unspecified sites Both 1226 5853 2 neoplasms darkcyan 5853, 1226 1463, 303 1463, 297 1463, 325 1463, 301 0.0233 0.0318 0.465 0.3327 1.02 0.962 1.09 -0.0271 0.0901 0.764 0.1171 0.973 0.816 1.16 0.0667 0.0885 0.451 0.3456 1.07 0.899 1.27 -0.00265 0.09 0.976 0.01034 0.997 0.836 1.19 PRS_PLINK_2.51188643150958e.06 FALSE 229.1 Benign neoplasm of lymph nodes Both 735 5453 2 neoplasms darkcyan 5453, 735 1363, 180 1363, 170 1363, 205 1363, 180 0.0537 0.0405 0.186 0.7314 1.06 0.975 1.14 -0.0728 0.114 0.523 0.2815 0.93 0.744 1.16 0.126 0.109 0.248 0.6059 1.13 0.916 1.41 -0.00223 0.113 0.984 0.006917 0.998 0.8 1.24 PRS_PLINK_2.51188643150958e.06 FALSE 240 Simple and unspecified goiter Both 283 1591 3 endocrine/metabolic brown 1591, 283 398, 68 398, 71 397, 71 398, 73 0.102 0.0691 0.142 0.849 1.11 0.967 1.27 0.0457 0.185 0.805 0.09441 1.05 0.729 1.5 0.0807 0.186 0.664 0.1776 1.08 0.753 1.56 0.085 0.183 0.643 0.192 1.09 0.76 1.56 PRS_PLINK_2.51188643150958e.06 FALSE 241 Nontoxic nodular goiter Both 731 3392 3 endocrine/metabolic brown 3392, 731 847, 177 848, 183 848, 186 848, 185 0.0342 0.0413 0.407 0.39 1.03 0.954 1.12 -0.00449 0.118 0.97 0.01344 0.996 0.791 1.25 0.06 0.118 0.61 0.2147 1.06 0.843 1.34 0.0372 0.117 0.751 0.1243 1.04 0.825 1.31 PRS_PLINK_2.51188643150958e.06 FALSE 241.1 Nontoxic uninodular goiter Both 607 3059 3 endocrine/metabolic brown 3059, 607 765, 143 765, 149 764, 160 765, 155 0.0287 0.0445 0.519 0.2852 1.03 0.943 1.12 -0.0041 0.129 0.975 0.01118 0.996 0.774 1.28 0.119 0.127 0.35 0.4559 1.13 0.878 1.45 0.0696 0.128 0.586 0.2324 1.07 0.835 1.38 PRS_PLINK_2.51188643150958e.06 FALSE 241.2 Nontoxic multinodular goiter Both 342 2023 3 endocrine/metabolic brown 2023, 342 506, 82 506, 90 505, 89 506, 81 0.0151 0.0585 0.796 0.099 1.02 0.905 1.14 0.082 0.166 0.622 0.2065 1.09 0.784 1.5 0.138 0.169 0.414 0.3833 1.15 0.825 1.6 -0.0165 0.17 0.923 0.03498 0.984 0.705 1.37 PRS_PLINK_2.51188643150958e.06 FALSE 242 Thyrotoxicosis with or without goiter Both 434 2173 3 endocrine/metabolic brown 2173, 434 544, 95 543, 126 543, 117 543, 96 0.0399 0.0528 0.45 0.3463 1.04 0.938 1.15 0.293 0.149 0.0488 1.311 1.34 1 1.79 0.24 0.152 0.115 0.9391 1.27 0.943 1.71 0.0396 0.158 0.802 0.09556 1.04 0.763 1.42 PRS_PLINK_2.51188643150958e.06 FALSE 242.1 Graves' disease Both 134 819 3 endocrine/metabolic brown 819, 134 205, 28 205, 38 204, 41 205, 27 0.0316 0.0898 0.725 0.1397 1.03 0.865 1.23 0.296 0.267 0.267 0.5727 1.34 0.797 2.27 0.507 0.272 0.0625 1.204 1.66 0.974 2.83 -0.022 0.287 0.939 0.02738 0.978 0.557 1.72 PRS_PLINK_2.51188643150958e.06 FALSE 242.2 Toxic multinodular goiter Both 27 190 3 endocrine/metabolic brown 190, 27 48, 3 47, 7 47, 6 48, 11 0.443 0.233 0.0572 1.243 1.56 0.987 2.46 0.76 0.671 0.257 0.5897 2.14 0.574 7.96 0.737 0.688 0.284 0.5466 2.09 0.542 8.06 1.03 0.641 0.109 0.9631 2.79 0.796 9.8 PRS_PLINK_2.51188643150958e.06 TRUE 242.3 Exophthalmos Both 72 441 3 endocrine/metabolic brown 441, 72 110, 20 110, 22 110, 21 110, 9 -0.136 0.111 0.222 0.6543 0.873 0.702 1.09 0.0851 0.338 0.801 0.09619 1.09 0.561 2.11 -0.0416 0.344 0.904 0.04402 0.959 0.489 1.88 -0.825 0.426 0.0526 1.279 0.438 0.19 1.01 PRS_PLINK_2.51188643150958e.06 FALSE 242.31 Thyrotoxic exophthalmos Both 32 228 3 endocrine/metabolic brown 228, 32 57, 6 57, 13 57, 9 57, 4 -0.151 0.166 0.364 0.4391 0.86 0.621 1.19 0.668 0.505 0.186 0.7306 1.95 0.725 5.25 0.555 0.567 0.328 0.4847 1.74 0.573 5.3 -0.518 0.676 0.444 0.3529 0.596 0.158 2.24 PRS_PLINK_2.51188643150958e.06 TRUE 244 Hypothyroidism Both 1911 4690 3 endocrine/metabolic brown 4690, 1911 1172, 475 1172, 484 1172, 476 1173, 476 0.00601 0.0281 0.831 0.08055 1.01 0.952 1.06 -0.0135 0.0798 0.866 0.06264 0.987 0.844 1.15 -0.000836 0.0802 0.992 0.003627 0.999 0.854 1.17 0.0209 0.0796 0.793 0.1008 1.02 0.874 1.19 PRS_PLINK_2.51188643150958e.06 FALSE 244.1 Secondary hypothyroidism Both 381 2633 3 endocrine/metabolic brown 2633, 381 658, 93 658, 83 658, 110 658, 95 0.0329 0.0556 0.555 0.2561 1.03 0.927 1.15 -0.141 0.161 0.379 0.421 0.868 0.634 1.19 0.157 0.153 0.307 0.5123 1.17 0.866 1.58 0.0269 0.157 0.864 0.06353 1.03 0.755 1.4 PRS_PLINK_2.51188643150958e.06 FALSE 244.2 Acquired hypothyroidism Both 425 1917 3 endocrine/metabolic brown 1917, 425 480, 118 479, 93 479, 98 479, 116 -0.0163 0.0504 0.747 0.127 0.984 0.891 1.09 -0.236 0.153 0.124 0.9066 0.79 0.585 1.07 -0.167 0.152 0.272 0.5659 0.846 0.628 1.14 0.0161 0.147 0.913 0.03955 1.02 0.762 1.36 PRS_PLINK_2.51188643150958e.06 FALSE 244.4 Hypothyroidism NOS Both 1846 4649 3 endocrine/metabolic brown 4649, 1846 1162, 463 1162, 473 1162, 458 1162, 452 0.000465 0.0284 0.987 0.005696 1 0.946 1.06 -0.0113 0.0805 0.888 0.05153 0.989 0.844 1.16 -0.0208 0.0811 0.798 0.0982 0.979 0.835 1.15 -0.00633 0.0808 0.938 0.02798 0.994 0.848 1.16 PRS_PLINK_2.51188643150958e.06 FALSE 245 Thyroiditis Both 250 1239 3 endocrine/metabolic brown 1239, 250 310, 58 310, 64 309, 64 310, 64 0.0605 0.07 0.388 0.4117 1.06 0.926 1.22 0.082 0.198 0.679 0.1681 1.09 0.736 1.6 0.0715 0.199 0.72 0.143 1.07 0.727 1.59 0.0899 0.199 0.652 0.1858 1.09 0.74 1.62 PRS_PLINK_2.51188643150958e.06 FALSE 245.2 Chronic thyroiditis Both 201 1028 3 endocrine/metabolic brown 1028, 201 257, 45 257, 51 257, 54 257, 51 0.0541 0.0767 0.481 0.3182 1.06 0.908 1.23 0.0489 0.223 0.827 0.08276 1.05 0.678 1.63 0.165 0.221 0.457 0.3398 1.18 0.764 1.82 0.158 0.224 0.479 0.3193 1.17 0.755 1.82 PRS_PLINK_2.51188643150958e.06 FALSE 245.21 Chronic lymphocytic thyroiditis Both 199 1013 3 endocrine/metabolic brown 1013, 199 254, 45 253, 50 253, 53 253, 51 0.0533 0.0766 0.487 0.3127 1.05 0.908 1.23 0.0698 0.224 0.755 0.1218 1.07 0.691 1.66 0.142 0.221 0.52 0.2837 1.15 0.747 1.78 0.17 0.223 0.448 0.3486 1.18 0.765 1.84 PRS_PLINK_2.51188643150958e.06 FALSE 246 Other disorders of thyroid Both 1446 4430 3 endocrine/metabolic brown 4430, 1446 1107, 364 1107, 372 1107, 344 1108, 366 0.00457 0.0313 0.884 0.05353 1 0.945 1.07 -0.0425 0.089 0.632 0.1989 0.958 0.805 1.14 -0.0687 0.0899 0.445 0.3516 0.934 0.783 1.11 0.0157 0.0883 0.859 0.06604 1.02 0.854 1.21 PRS_PLINK_2.51188643150958e.06 FALSE 246.2 Thyroid cyst Both 28 163 3 endocrine/metabolic brown 163, 28 41, 7 41, 7 40, 4 41, 10 -0.0865 0.196 0.659 0.1814 0.917 0.625 1.35 0.084 0.58 0.885 0.05316 1.09 0.349 3.39 -0.468 0.631 0.458 0.3387 0.627 0.182 2.16 0.268 0.561 0.633 0.1988 1.31 0.435 3.93 PRS_PLINK_2.51188643150958e.06 TRUE 246.7 Abnormal results of function study of thyroid Both 348 1411 3 endocrine/metabolic brown 1411, 348 353, 91 353, 78 352, 97 353, 82 0.0264 0.0593 0.656 0.183 1.03 0.914 1.15 -0.137 0.173 0.428 0.3687 0.872 0.622 1.22 0.077 0.165 0.64 0.1935 1.08 0.782 1.49 -0.0545 0.171 0.751 0.1246 0.947 0.677 1.32 PRS_PLINK_2.51188643150958e.06 FALSE 249 Secondary diabetes mellitus Both 494 911 3 endocrine/metabolic brown 911, 494 228, 130 228, 149 227, 90 228, 125 -0.0297 0.0637 0.641 0.1933 0.971 0.857 1.1 0.0449 0.17 0.791 0.1016 1.05 0.75 1.46 -0.329 0.181 0.0691 1.161 0.72 0.505 1.03 -0.0458 0.173 0.791 0.1019 0.955 0.681 1.34 PRS_PLINK_2.51188643150958e.06 FALSE 250 Diabetes mellitus Both 3856 3548 3 endocrine/metabolic brown 3548, 3856 887, 941 887, 967 887, 955 887, 992 0.0317 0.025 0.205 0.6891 1.03 0.983 1.08 0.0183 0.0711 0.797 0.09859 1.02 0.886 1.17 0.0368 0.0709 0.604 0.2189 1.04 0.903 1.19 0.0641 0.0707 0.365 0.4381 1.07 0.928 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 250.1 Type 1 diabetes Both 891 1324 3 endocrine/metabolic brown 1324, 891 331, 235 331, 216 331, 209 331, 231 0.0069 0.0533 0.897 0.04728 1.01 0.907 1.12 -0.0647 0.15 0.665 0.1769 0.937 0.699 1.26 -0.0514 0.147 0.727 0.1383 0.95 0.711 1.27 0.0665 0.146 0.648 0.1882 1.07 0.803 1.42 PRS_PLINK_2.51188643150958e.06 FALSE 250.11 Type 1 diabetes with ketoacidosis Both 93 105 3 endocrine/metabolic brown 105, 93 27, 22 26, 33 26, 14 26, 24 0.00732 0.156 0.963 0.01657 1.01 0.742 1.37 0.53 0.456 0.245 0.611 1.7 0.695 4.15 -0.656 0.535 0.22 0.6572 0.519 0.182 1.48 0.179 0.469 0.702 0.1538 1.2 0.478 3 PRS_PLINK_2.51188643150958e.06 FALSE 250.12 Type 1 diabetes with renal manifestations Both 216 297 3 endocrine/metabolic brown 297, 216 75, 51 74, 38 74, 55 74, 72 0.094 0.107 0.381 0.4185 1.1 0.89 1.36 -0.258 0.334 0.44 0.3563 0.773 0.401 1.49 0.175 0.292 0.55 0.2598 1.19 0.671 2.11 0.437 0.292 0.135 0.87 1.55 0.873 2.74 PRS_PLINK_2.51188643150958e.06 FALSE 250.13 Type 1 diabetes with ophthalmic manifestations Both 296 314 3 endocrine/metabolic brown 314, 296 79, 84 78, 61 78, 68 79, 83 0.0532 0.0961 0.58 0.2366 1.05 0.874 1.27 -0.168 0.28 0.548 0.2612 0.845 0.488 1.46 -0.224 0.278 0.421 0.3753 0.799 0.463 1.38 0.0424 0.268 0.874 0.05843 1.04 0.617 1.76 PRS_PLINK_2.51188643150958e.06 FALSE 250.14 Type 1 diabetes with neurological manifestations Both 273 285 3 endocrine/metabolic brown 285, 273 72, 71 71, 72 71, 52 71, 78 -0.0208 0.0995 0.835 0.07845 0.979 0.806 1.19 0.037 0.291 0.899 0.04642 1.04 0.587 1.83 -0.209 0.299 0.485 0.3142 0.812 0.452 1.46 0.0736 0.29 0.8 0.09687 1.08 0.609 1.9 PRS_PLINK_2.51188643150958e.06 FALSE 250.15 Diabetes type 1 with peripheral circulatory disorders Both 76 87 3 endocrine/metabolic brown 87, 76 22, 22 22, 19 21, 12 22, 23 -0.169 0.156 0.278 0.5561 0.844 0.622 1.15 0.157 0.526 0.765 0.1166 1.17 0.418 3.28 -0.651 0.542 0.23 0.6383 0.522 0.18 1.51 0.201 0.479 0.674 0.171 1.22 0.478 3.13 PRS_PLINK_2.51188643150958e.06 FALSE 250.2 Type 2 diabetes Both 2625 3398 3 endocrine/metabolic brown 3398, 2625 850, 666 849, 653 849, 631 850, 674 0.00822 0.0286 0.774 0.1114 1.01 0.953 1.07 -0.0392 0.0814 0.631 0.2002 0.962 0.82 1.13 -0.031 0.0813 0.703 0.1532 0.969 0.827 1.14 -0.00278 0.081 0.973 0.01206 0.997 0.851 1.17 PRS_PLINK_2.51188643150958e.06 FALSE 250.21 Type 2 diabetes with ketoacidosis Both 119 145 3 endocrine/metabolic brown 145, 119 37, 30 36, 40 36, 17 36, 32 0.0464 0.139 0.738 0.132 1.05 0.798 1.37 0.215 0.38 0.571 0.2433 1.24 0.589 2.61 -0.781 0.449 0.0819 1.087 0.458 0.19 1.1 0.139 0.376 0.712 0.1478 1.15 0.55 2.4 PRS_PLINK_2.51188643150958e.06 FALSE 250.22 Type 2 diabetes with renal manifestations Both 874 1569 3 endocrine/metabolic brown 1569, 874 393, 221 392, 196 392, 237 392, 219 0.00591 0.047 0.9 0.04583 1.01 0.917 1.1 -0.126 0.137 0.36 0.4439 0.882 0.674 1.15 0.106 0.131 0.42 0.3767 1.11 0.86 1.44 0.0049 0.134 0.971 0.01281 1 0.772 1.31 PRS_PLINK_2.51188643150958e.06 FALSE 250.23 Type 2 diabetes with ophthalmic manifestations Both 702 1125 3 endocrine/metabolic brown 1125, 702 282, 201 281, 160 281, 167 281, 173 -0.0483 0.0554 0.383 0.4166 0.953 0.855 1.06 -0.297 0.162 0.0659 1.181 0.743 0.541 1.02 -0.173 0.156 0.268 0.5721 0.841 0.62 1.14 -0.208 0.159 0.189 0.7232 0.812 0.595 1.11 PRS_PLINK_2.51188643150958e.06 FALSE 250.24 Type 2 diabetes with neurological manifestations Both 1157 1894 3 endocrine/metabolic brown 1894, 1157 474, 324 473, 276 473, 269 474, 287 -0.0645 0.0412 0.117 0.9312 0.938 0.865 1.02 -0.148 0.119 0.217 0.6637 0.863 0.683 1.09 -0.216 0.12 0.0708 1.15 0.805 0.637 1.02 -0.162 0.119 0.175 0.7577 0.85 0.673 1.07 PRS_PLINK_2.51188643150958e.06 FALSE 250.25 Diabetes type 2 with peripheral circulatory disorders Both 430 701 3 endocrine/metabolic brown 701, 430 176, 120 175, 102 175, 95 175, 113 0.0122 0.0707 0.863 0.06422 1.01 0.881 1.16 -0.25 0.202 0.216 0.6657 0.779 0.524 1.16 -0.131 0.193 0.497 0.3038 0.877 0.601 1.28 -0.00885 0.193 0.963 0.01622 0.991 0.679 1.45 PRS_PLINK_2.51188643150958e.06 FALSE 250.3 Insulin pump user Both 1204 2358 3 endocrine/metabolic brown 2358, 1204 590, 328 589, 292 589, 275 590, 308 -0.0328 0.0407 0.42 0.3763 0.968 0.894 1.05 -0.18 0.118 0.129 0.8895 0.836 0.663 1.05 -0.117 0.116 0.313 0.5038 0.89 0.709 1.12 -0.132 0.117 0.259 0.5865 0.877 0.697 1.1 PRS_PLINK_2.51188643150958e.06 FALSE 250.4 Abnormal glucose Both 2886 3476 3 endocrine/metabolic brown 3476, 2886 869, 688 869, 702 869, 734 869, 761 0.0544 0.0273 0.0461 1.337 1.06 1 1.11 0.0043 0.0781 0.956 0.0195 1 0.862 1.17 0.0939 0.0772 0.224 0.6497 1.1 0.944 1.28 0.129 0.0769 0.0941 1.027 1.14 0.978 1.32 PRS_PLINK_2.51188643150958e.06 FALSE 250.41 Impaired fasting glucose Both 718 1908 3 endocrine/metabolic brown 1908, 718 477, 155 477, 180 477, 197 477, 186 0.0912 0.0478 0.0562 1.25 1.1 0.998 1.2 0.161 0.135 0.232 0.634 1.17 0.902 1.53 0.275 0.132 0.0378 1.422 1.32 1.02 1.71 0.235 0.134 0.079 1.103 1.26 0.973 1.64 PRS_PLINK_2.51188643150958e.06 FALSE 250.42 Other abnormal glucose Both 2609 3424 3 endocrine/metabolic brown 3424, 2609 856, 621 856, 651 856, 654 856, 682 0.0506 0.0281 0.0713 1.147 1.05 0.996 1.11 0.0372 0.0807 0.645 0.1906 1.04 0.886 1.22 0.102 0.0802 0.205 0.6884 1.11 0.946 1.3 0.13 0.0798 0.103 0.9876 1.14 0.974 1.33 PRS_PLINK_2.51188643150958e.06 FALSE 250.5 Glycosuria or Acetonuria Both 58 114 3 endocrine/metabolic brown 114, 58 29, 12 28, 16 28, 16 29, 14 0.0424 0.18 0.814 0.08944 1.04 0.733 1.49 0.267 0.513 0.603 0.2199 1.31 0.478 3.57 0.186 0.523 0.722 0.1414 1.2 0.432 3.35 0.279 0.496 0.574 0.241 1.32 0.5 3.49 PRS_PLINK_2.51188643150958e.06 FALSE 250.6 Polyneuropathy in diabetes Both 981 1548 3 endocrine/metabolic brown 1548, 981 387, 274 387, 225 387, 235 387, 246 -0.0576 0.045 0.2 0.698 0.944 0.864 1.03 -0.165 0.134 0.216 0.6663 0.847 0.652 1.1 -0.172 0.132 0.192 0.716 0.842 0.65 1.09 -0.185 0.134 0.167 0.7761 0.832 0.64 1.08 PRS_PLINK_2.51188643150958e.06 FALSE 250.7 Diabetic retinopathy Both 691 1479 3 endocrine/metabolic brown 1479, 691 370, 195 370, 156 369, 171 370, 168 -0.00567 0.0481 0.906 0.04278 0.994 0.905 1.09 -0.24 0.136 0.0783 1.106 0.787 0.602 1.03 -0.0727 0.134 0.587 0.2316 0.93 0.716 1.21 -0.113 0.136 0.404 0.3932 0.893 0.684 1.17 PRS_PLINK_2.51188643150958e.06 FALSE 251 Other disorders of pancreatic internal secretion Both 411 1360 3 endocrine/metabolic brown 1360, 411 339, 133 340, 99 340, 90 340, 89 -0.141 0.0576 0.0142 1.849 0.868 0.776 0.972 -0.291 0.154 0.0595 1.226 0.748 0.553 1.01 -0.428 0.159 0.00696 2.157 0.652 0.478 0.889 -0.422 0.159 0.00791 2.102 0.656 0.48 0.895 PRS_PLINK_2.51188643150958e.06 FALSE 251.1 Hypoglycemia Both 491 941 3 endocrine/metabolic brown 941, 491 236, 138 235, 140 235, 105 235, 108 -0.0459 0.0613 0.455 0.3423 0.955 0.847 1.08 -0.0463 0.168 0.782 0.1066 0.955 0.687 1.33 -0.159 0.17 0.351 0.4545 0.853 0.611 1.19 -0.195 0.172 0.256 0.5919 0.823 0.587 1.15 PRS_PLINK_2.51188643150958e.06 FALSE 252 Disorders of parathyroid gland Both 644 3302 3 endocrine/metabolic brown 3302, 644 826, 161 825, 150 825, 147 826, 186 0.0225 0.0437 0.606 0.2178 1.02 0.939 1.11 -0.0713 0.124 0.565 0.248 0.931 0.731 1.19 -0.0813 0.125 0.514 0.2891 0.922 0.722 1.18 0.147 0.119 0.216 0.6651 1.16 0.918 1.46 PRS_PLINK_2.51188643150958e.06 FALSE 252.1 Hyperparathyroidism Both 594 3075 3 endocrine/metabolic brown 3075, 594 769, 148 769, 137 768, 138 769, 171 0.0292 0.0454 0.52 0.2842 1.03 0.942 1.13 -0.0737 0.129 0.568 0.2456 0.929 0.721 1.2 -0.0579 0.129 0.655 0.184 0.944 0.732 1.22 0.147 0.123 0.233 0.6332 1.16 0.91 1.48 PRS_PLINK_2.51188643150958e.06 FALSE 252.2 Hypoparathyroidism Both 122 719 3 endocrine/metabolic brown 719, 122 180, 31 180, 28 179, 28 180, 35 -0.0731 0.103 0.476 0.3226 0.93 0.76 1.14 -0.0247 0.286 0.931 0.03097 0.976 0.558 1.71 -0.109 0.286 0.703 0.153 0.897 0.512 1.57 0.146 0.271 0.59 0.2294 1.16 0.68 1.97 PRS_PLINK_2.51188643150958e.06 FALSE 253 Disorders of the pituitary gland and its hypothalamic control Both 224 1217 3 endocrine/metabolic brown 1217, 224 305, 68 304, 55 304, 39 304, 62 0.00367 0.0788 0.963 0.01645 1 0.86 1.17 -0.202 0.198 0.309 0.5098 0.817 0.554 1.21 -0.559 0.215 0.00943 2.026 0.572 0.375 0.872 -0.0863 0.194 0.656 0.1834 0.917 0.628 1.34 PRS_PLINK_2.51188643150958e.06 FALSE 253.1 Pituitary hyperfunction Both 58 373 3 endocrine/metabolic brown 373, 58 94, 18 93, 15 93, 8 93, 17 -0.0453 0.156 0.771 0.1127 0.956 0.704 1.3 -0.17 0.386 0.66 0.1806 0.844 0.396 1.8 -0.696 0.436 0.11 0.9576 0.499 0.212 1.17 -0.137 0.375 0.714 0.1465 0.872 0.418 1.82 PRS_PLINK_2.51188643150958e.06 FALSE 253.11 Acromegaly and gigantism Both 8 101 3 endocrine/metabolic brown 101, 8 26, 3 25, 2 25, 1 25, 2 -0.113 0.339 0.739 0.1314 0.893 0.459 1.74 -0.48 0.858 0.576 0.2394 0.619 0.115 3.33 -1.07 0.969 0.271 0.5663 0.344 0.0515 2.3 -0.0667 0.869 0.939 0.02741 0.935 0.17 5.14 PRS_PLINK_2.51188643150958e.06 TRUE 253.2 Pituitary hypofunction Both 57 312 3 endocrine/metabolic brown 312, 57 78, 13 78, 18 78, 13 78, 13 -0.00767 0.152 0.96 0.01789 0.992 0.737 1.34 0.295 0.39 0.448 0.3483 1.34 0.626 2.88 -0.104 0.416 0.802 0.09587 0.901 0.399 2.04 -0.144 0.427 0.736 0.1332 0.866 0.375 2 PRS_PLINK_2.51188643150958e.06 FALSE 253.3 Diabetes insipidus Both 25 121 3 endocrine/metabolic brown 121, 25 31, 8 30, 3 30, 5 30, 9 0.195 0.29 0.502 0.2992 1.22 0.688 2.15 -0.892 0.679 0.189 0.7237 0.41 0.108 1.55 -0.379 0.621 0.541 0.2664 0.684 0.203 2.31 -0.324 0.651 0.619 0.2085 0.723 0.202 2.59 PRS_PLINK_2.51188643150958e.06 TRUE 253.4 Anterior pituitary disorders Both 48 197 3 endocrine/metabolic brown 197, 48 50, 9 49, 14 49, 9 49, 16 0.136 0.172 0.427 0.3697 1.15 0.819 1.6 0.562 0.487 0.248 0.6051 1.76 0.675 4.56 0.107 0.505 0.832 0.08 1.11 0.413 3 0.483 0.484 0.318 0.4971 1.62 0.627 4.19 PRS_PLINK_2.51188643150958e.06 TRUE 253.7 Other disorders of neurohypophysis Both 36 154 3 endocrine/metabolic brown 154, 36 39, 16 38, 7 38, 2 39, 11 -0.0647 0.176 0.714 0.1464 0.937 0.663 1.32 -0.922 0.521 0.077 1.114 0.398 0.143 1.1 -1.77 0.694 0.0106 1.974 0.17 0.0436 0.662 -0.325 0.461 0.481 0.3181 0.723 0.293 1.78 PRS_PLINK_2.51188643150958e.06 TRUE 255 Disorders of adrenal glands Both 485 2224 3 endocrine/metabolic brown 2224, 485 556, 137 556, 116 556, 114 556, 118 -0.0563 0.0489 0.25 0.6029 0.945 0.859 1.04 -0.151 0.14 0.282 0.5504 0.86 0.654 1.13 -0.192 0.141 0.171 0.7671 0.825 0.626 1.09 -0.158 0.14 0.258 0.5877 0.854 0.649 1.12 PRS_PLINK_2.51188643150958e.06 FALSE 255.1 Adrenal hyperfunction Both 112 575 3 endocrine/metabolic brown 575, 112 143, 34 144, 25 143, 26 144, 27 -0.0949 0.0948 0.317 0.4995 0.909 0.755 1.1 -0.278 0.293 0.342 0.4655 0.757 0.427 1.34 -0.286 0.29 0.324 0.4892 0.752 0.426 1.33 -0.227 0.29 0.434 0.3625 0.797 0.451 1.41 PRS_PLINK_2.51188643150958e.06 FALSE 255.11 Cushing's syndrome Both 56 269 3 endocrine/metabolic brown 269, 56 68, 18 67, 16 67, 13 67, 9 -0.185 0.133 0.164 0.7864 0.831 0.64 1.08 -0.0239 0.409 0.953 0.02073 0.976 0.438 2.18 -0.25 0.416 0.549 0.2608 0.779 0.345 1.76 -0.557 0.449 0.215 0.6672 0.573 0.238 1.38 PRS_PLINK_2.51188643150958e.06 FALSE 255.12 Hyperaldosteronism Both 37 198 3 endocrine/metabolic brown 198, 37 50, 13 49, 4 49, 7 50, 13 0.00622 0.171 0.971 0.0128 1.01 0.72 1.41 -1.04 0.603 0.0848 1.072 0.354 0.109 1.15 -0.31 0.519 0.549 0.26 0.733 0.265 2.03 0.235 0.478 0.622 0.2061 1.27 0.496 3.23 PRS_PLINK_2.51188643150958e.06 TRUE 255.2 Adrenal hypofunction Both 247 914 3 endocrine/metabolic brown 914, 247 229, 71 228, 63 228, 52 229, 61 -0.0852 0.0699 0.223 0.6511 0.918 0.801 1.05 -0.0779 0.199 0.695 0.1581 0.925 0.627 1.37 -0.338 0.207 0.102 0.9903 0.713 0.475 1.07 -0.114 0.202 0.572 0.2424 0.892 0.601 1.33 PRS_PLINK_2.51188643150958e.06 FALSE 255.21 Glucocorticoid deficiency Both 237 870 3 endocrine/metabolic brown 870, 237 218, 70 217, 62 217, 50 218, 55 -0.124 0.0704 0.0782 1.107 0.883 0.77 1.01 -0.0779 0.201 0.699 0.1558 0.925 0.624 1.37 -0.38 0.211 0.0719 1.144 0.684 0.452 1.03 -0.213 0.207 0.305 0.5152 0.808 0.538 1.21 PRS_PLINK_2.51188643150958e.06 FALSE 256 Ovarian dysfunction Female 342 1495 3 endocrine/metabolic brown 1495, 342 374, 89 374, 83 373, 75 374, 95 -0.00359 0.0605 0.953 0.02103 0.996 0.885 1.12 -0.0548 0.169 0.746 0.1273 0.947 0.679 1.32 -0.162 0.173 0.35 0.4558 0.85 0.605 1.19 0.104 0.166 0.529 0.2768 1.11 0.802 1.54 PRS_PLINK_2.51188643150958e.06 FALSE 256.4 Polycystic ovaries Female 228 982 3 endocrine/metabolic brown 982, 228 246, 59 245, 59 245, 51 246, 59 -0.00163 0.0738 0.982 0.007712 0.998 0.864 1.15 -0.01 0.206 0.961 0.01714 0.99 0.661 1.48 -0.132 0.213 0.534 0.2725 0.876 0.577 1.33 0.05 0.208 0.81 0.0916 1.05 0.699 1.58 PRS_PLINK_2.51188643150958e.06 FALSE 257 Testicular dysfunction Male 344 1168 3 endocrine/metabolic brown 1168, 344 292, 91 292, 91 292, 82 292, 80 -0.0804 0.0605 0.183 0.7366 0.923 0.82 1.04 -0.0307 0.171 0.858 0.06672 0.97 0.694 1.36 -0.11 0.176 0.532 0.2744 0.896 0.635 1.26 -0.137 0.174 0.431 0.3655 0.872 0.619 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 257.1 Testicular hypofunction Male 339 1133 3 endocrine/metabolic brown 1133, 339 284, 89 283, 88 283, 80 283, 82 -0.0713 0.0616 0.247 0.6072 0.931 0.825 1.05 -0.0323 0.173 0.852 0.06948 0.968 0.69 1.36 -0.102 0.178 0.567 0.2467 0.903 0.638 1.28 -0.0768 0.175 0.661 0.1799 0.926 0.657 1.3 PRS_PLINK_2.51188643150958e.06 FALSE 258 Iatrogenic endocrine disorders Both 31 142 3 endocrine/metabolic brown 142, 31 36, 11 35, 8 35, 7 36, 5 -0.246 0.169 0.146 0.8364 0.782 0.562 1.09 -0.122 0.562 0.828 0.08213 0.885 0.294 2.66 -0.443 0.615 0.471 0.3268 0.642 0.192 2.14 -0.65 0.566 0.251 0.6009 0.522 0.172 1.58 PRS_PLINK_2.51188643150958e.06 TRUE 258.1 Postablative ovarian failure Female 35 158 3 endocrine/metabolic brown 158, 35 40, 9 39, 10 39, 7 40, 9 0.0346 0.18 0.847 0.07202 1.04 0.728 1.47 0.047 0.503 0.926 0.0336 1.05 0.391 2.81 -0.0915 0.555 0.869 0.06094 0.913 0.307 2.71 -0.0887 0.528 0.867 0.06216 0.915 0.325 2.58 PRS_PLINK_2.51188643150958e.06 TRUE 259 Other endocrine disorders Both 322 1547 3 endocrine/metabolic brown 1547, 322 387, 77 387, 87 386, 85 387, 73 0.0501 0.0617 0.417 0.3801 1.05 0.932 1.19 0.151 0.173 0.385 0.4148 1.16 0.828 1.63 0.0851 0.172 0.622 0.2064 1.09 0.777 1.53 -0.0515 0.178 0.772 0.1122 0.95 0.67 1.35 PRS_PLINK_2.51188643150958e.06 FALSE 260 Protein-calorie malnutrition Both 1027 2531 3 endocrine/metabolic brown 2531, 1027 633, 261 633, 246 632, 251 633, 268 0.00629 0.0372 0.866 0.06249 1.01 0.935 1.08 -0.0659 0.106 0.535 0.272 0.936 0.761 1.15 -0.0429 0.105 0.684 0.165 0.958 0.779 1.18 0.0156 0.104 0.881 0.05506 1.02 0.828 1.25 PRS_PLINK_2.51188643150958e.06 FALSE 260.1 Cachexia Both 128 273 3 endocrine/metabolic brown 273, 128 69, 34 68, 30 68, 35 68, 28 -0.14 0.109 0.198 0.7031 0.869 0.702 1.08 -0.0902 0.309 0.771 0.1132 0.914 0.498 1.68 0.0243 0.306 0.937 0.02837 1.02 0.563 1.87 -0.169 0.317 0.595 0.2253 0.845 0.454 1.57 PRS_PLINK_2.51188643150958e.06 FALSE 260.2 severe protein-calorie malnutrition Both 609 1586 3 endocrine/metabolic brown 1586, 609 397, 171 396, 139 396, 158 397, 140 -0.0635 0.0467 0.174 0.7583 0.938 0.856 1.03 -0.203 0.137 0.137 0.8631 0.816 0.625 1.07 -0.0963 0.133 0.47 0.3283 0.908 0.7 1.18 -0.206 0.136 0.132 0.8804 0.814 0.623 1.06 PRS_PLINK_2.51188643150958e.06 FALSE 260.22 Nutritional marasmus Both 233 547 3 endocrine/metabolic brown 547, 233 137, 66 137, 57 136, 55 137, 55 -0.0272 0.0831 0.743 0.1289 0.973 0.827 1.15 -0.0909 0.226 0.688 0.1623 0.913 0.586 1.42 -0.205 0.226 0.366 0.4365 0.815 0.523 1.27 -0.155 0.227 0.496 0.3043 0.857 0.549 1.34 PRS_PLINK_2.51188643150958e.06 FALSE 260.3 Adult failure to thrive Both 288 618 3 endocrine/metabolic brown 618, 288 155, 64 154, 76 154, 62 155, 85 0.072 0.0777 0.354 0.4505 1.07 0.923 1.25 0.168 0.209 0.422 0.3746 1.18 0.785 1.78 -0.0579 0.217 0.79 0.1026 0.944 0.617 1.44 0.247 0.204 0.226 0.6466 1.28 0.859 1.91 PRS_PLINK_2.51188643150958e.06 FALSE 260.6 Anorexia Both 379 856 3 endocrine/metabolic brown 856, 379 214, 105 214, 90 214, 99 214, 85 -0.0772 0.0621 0.214 0.6699 0.926 0.82 1.05 -0.169 0.178 0.343 0.4642 0.844 0.595 1.2 -0.12 0.175 0.492 0.3082 0.887 0.63 1.25 -0.212 0.178 0.233 0.6324 0.809 0.571 1.15 PRS_PLINK_2.51188643150958e.06 FALSE 260.7 Polyphagia Both 29 66 3 endocrine/metabolic brown 66, 29 17, 8 16, 5 16, 7 17, 9 0.173 0.209 0.409 0.3878 1.19 0.789 1.79 -0.477 0.817 0.559 0.2523 0.621 0.125 3.08 -0.00964 0.703 0.989 0.004777 0.99 0.25 3.93 0.282 0.735 0.701 0.1544 1.33 0.314 5.6 PRS_PLINK_2.51188643150958e.06 TRUE 261 Vitamin deficiency Both 3346 3124 3 endocrine/metabolic brown 3124, 3346 781, 827 781, 793 781, 813 781, 913 0.0203 0.0255 0.427 0.3698 1.02 0.971 1.07 -0.0482 0.0724 0.506 0.2962 0.953 0.827 1.1 -0.00478 0.0724 0.947 0.02346 0.995 0.864 1.15 0.111 0.0717 0.122 0.9136 1.12 0.971 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 261.1 Vitamin A deficiency Both 33 56 3 endocrine/metabolic brown 56, 33 14, 9 14, 8 14, 6 14, 10 0.111 0.256 0.663 0.1782 1.12 0.677 1.85 -0.756 0.873 0.386 0.4132 0.469 0.0849 2.6 -0.665 0.761 0.382 0.4179 0.514 0.116 2.28 0.309 0.654 0.637 0.1962 1.36 0.378 4.9 PRS_PLINK_2.51188643150958e.06 TRUE 261.2 Vitamin B-complex deficiencies Both 584 887 3 endocrine/metabolic brown 887, 584 222, 146 222, 122 221, 144 222, 172 0.0642 0.053 0.226 0.6468 1.07 0.961 1.18 -0.15 0.158 0.342 0.4656 0.861 0.632 1.17 0.0181 0.155 0.907 0.04238 1.02 0.751 1.38 0.168 0.149 0.258 0.5884 1.18 0.884 1.58 PRS_PLINK_2.51188643150958e.06 FALSE 261.4 Vitamin D deficiency Both 3110 3123 3 endocrine/metabolic brown 3123, 3110 781, 759 781, 753 780, 750 781, 848 0.0165 0.0261 0.526 0.2786 1.02 0.966 1.07 -0.0126 0.0739 0.865 0.06313 0.987 0.854 1.14 0.00455 0.0742 0.951 0.02178 1 0.869 1.16 0.123 0.0735 0.0935 1.029 1.13 0.979 1.31 PRS_PLINK_2.51188643150958e.06 FALSE 261.41 Rickets or osteomalacia Both 21 47 3 endocrine/metabolic brown 47, 21 12, 5 12, 5 11, 5 12, 6 0.0965 0.233 0.679 0.1681 1.1 0.697 1.74 -0.00845 0.876 0.992 0.003357 0.992 0.178 5.52 -0.677 1.04 0.516 0.2872 0.508 0.0659 3.92 0.0853 0.813 0.916 0.03791 1.09 0.221 5.36 PRS_PLINK_2.51188643150958e.06 TRUE 262 Mineral deficiency NEC Both 668 1137 3 endocrine/metabolic brown 1137, 668 285, 168 284, 145 284, 163 284, 192 0.0307 0.0517 0.553 0.2571 1.03 0.932 1.14 -0.157 0.144 0.276 0.5587 0.855 0.645 1.13 -0.0208 0.141 0.883 0.05424 0.979 0.744 1.29 0.125 0.136 0.36 0.4434 1.13 0.867 1.48 PRS_PLINK_2.51188643150958e.06 FALSE 263 Other nutritional deficiency Both 632 1552 3 endocrine/metabolic brown 1552, 632 388, 173 388, 146 388, 147 388, 166 -0.00797 0.046 0.862 0.06424 0.992 0.906 1.09 -0.162 0.134 0.226 0.6458 0.85 0.654 1.11 -0.166 0.134 0.215 0.6668 0.847 0.651 1.1 -0.0458 0.131 0.727 0.1387 0.955 0.739 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 264 Lack of normal physiological development Both 84 179 3 endocrine/metabolic brown 179, 84 45, 19 45, 19 44, 16 45, 30 0.126 0.141 0.372 0.4294 1.13 0.86 1.5 -0.0816 0.403 0.84 0.07591 0.922 0.418 2.03 -0.269 0.422 0.523 0.2812 0.764 0.334 1.75 0.278 0.385 0.47 0.3281 1.32 0.621 2.81 PRS_PLINK_2.51188643150958e.06 FALSE 264.2 Failure to thrive (childhood) Both 58 113 3 endocrine/metabolic brown 113, 58 29, 16 28, 14 28, 9 28, 19 0.0736 0.155 0.636 0.1968 1.08 0.794 1.46 -0.268 0.486 0.581 0.2357 0.765 0.295 1.98 -0.745 0.567 0.189 0.7245 0.475 0.156 1.44 -0.0143 0.474 0.976 0.01055 0.986 0.389 2.5 PRS_PLINK_2.51188643150958e.06 FALSE 264.9 Lack of normal physiological development, unspecified Both 19 53 3 endocrine/metabolic brown 53, 19 14, 3 13, 4 13, 3 13, 9 0.372 0.38 0.327 0.4853 1.45 0.689 3.05 0.226 1.05 0.83 0.08081 1.25 0.159 9.89 1.71 1.35 0.203 0.6925 5.55 0.397 77.6 0.779 0.833 0.35 0.4564 2.18 0.426 11.1 PRS_PLINK_2.51188643150958e.06 TRUE 269 Proteinuria Both 795 2153 3 endocrine/metabolic brown 2153, 795 539, 212 538, 179 538, 198 538, 206 -0.00864 0.0416 0.835 0.07808 0.991 0.914 1.08 -0.159 0.119 0.183 0.7367 0.853 0.676 1.08 -0.0563 0.117 0.63 0.2009 0.945 0.752 1.19 -0.0156 0.116 0.893 0.04926 0.984 0.784 1.24 PRS_PLINK_2.51188643150958e.06 FALSE 270 Disorders of protein plasma/amino-acid transport and metabolism Both 457 1496 3 endocrine/metabolic brown 1496, 457 373, 116 374, 102 374, 108 374, 131 0.0277 0.0535 0.605 0.2182 1.03 0.926 1.14 -0.125 0.154 0.419 0.3781 0.883 0.652 1.19 -0.0762 0.153 0.619 0.2083 0.927 0.686 1.25 0.112 0.149 0.451 0.3461 1.12 0.836 1.5 PRS_PLINK_2.51188643150958e.06 FALSE 270.1 Disturbances of amino-acid transport Both 43 245 3 endocrine/metabolic brown 245, 43 62, 10 61, 10 61, 12 61, 11 0.077 0.187 0.68 0.1673 1.08 0.749 1.56 0.17 0.482 0.725 0.1396 1.18 0.461 3.05 0.257 0.493 0.603 0.2198 1.29 0.492 3.4 0.267 0.479 0.578 0.2383 1.31 0.51 3.34 PRS_PLINK_2.51188643150958e.06 TRUE 270.11 Disturbances of sulphur-bearing amino-acid metabolism Both 37 194 3 endocrine/metabolic brown 194, 37 49, 9 48, 9 48, 12 49, 7 -0.00661 0.192 0.972 0.01212 0.993 0.682 1.45 0.141 0.513 0.783 0.1063 1.15 0.421 3.15 0.346 0.508 0.496 0.3044 1.41 0.522 3.83 -0.189 0.534 0.724 0.1405 0.828 0.291 2.36 PRS_PLINK_2.51188643150958e.06 TRUE 270.2 Disorders of amino-acid metabolism Both 42 138 3 endocrine/metabolic brown 138, 42 35, 11 34, 9 34, 11 35, 11 -0.0439 0.169 0.795 0.09965 0.957 0.687 1.33 -0.011 0.52 0.983 0.007423 0.989 0.357 2.74 0.132 0.52 0.799 0.09737 1.14 0.412 3.17 0.0892 0.519 0.863 0.06381 1.09 0.396 3.02 PRS_PLINK_2.51188643150958e.06 TRUE 270.3 Disorders of plasma protein metabolism Both 386 1165 3 endocrine/metabolic brown 1165, 386 291, 98 291, 87 291, 88 291, 113 0.03 0.0588 0.61 0.2149 1.03 0.918 1.16 -0.121 0.169 0.475 0.3231 0.886 0.636 1.23 -0.121 0.17 0.476 0.3221 0.886 0.635 1.24 0.126 0.162 0.436 0.3608 1.13 0.826 1.56 PRS_PLINK_2.51188643150958e.06 FALSE 270.32 Paraproteinemia Both 224 655 3 endocrine/metabolic brown 655, 224 163, 56 164, 49 163, 57 164, 62 0.00428 0.0718 0.952 0.02115 1 0.873 1.16 -0.095 0.228 0.677 0.1692 0.909 0.581 1.42 -0.0231 0.221 0.917 0.03779 0.977 0.634 1.51 0.105 0.217 0.627 0.2028 1.11 0.727 1.7 PRS_PLINK_2.51188643150958e.06 FALSE 270.33 Amyloidosis Both 24 105 3 endocrine/metabolic brown 105, 24 27, 8 26, 5 26, 6 26, 5 0.0767 0.236 0.745 0.1278 1.08 0.68 1.71 -0.862 0.709 0.224 0.6498 0.422 0.105 1.69 0.226 0.643 0.725 0.1397 1.25 0.355 4.43 -0.392 0.661 0.554 0.2568 0.676 0.185 2.47 PRS_PLINK_2.51188643150958e.06 TRUE 270.34 Alpha-1-antitrypsin deficiency Both 27 100 3 endocrine/metabolic brown 100, 27 25, 11 25, 3 25, 4 25, 9 -0.126 0.241 0.601 0.2214 0.881 0.549 1.41 -1.09 0.682 0.111 0.9534 0.338 0.0888 1.28 -0.746 0.662 0.26 0.5853 0.474 0.13 1.74 0.00164 0.576 0.998 0.0009903 1 0.324 3.1 PRS_PLINK_2.51188643150958e.06 TRUE 270.38 Other specified disorders of plasma protein metabolism Both 151 459 3 endocrine/metabolic brown 459, 151 115, 36 115, 34 114, 38 115, 43 0.112 0.101 0.265 0.5761 1.12 0.918 1.36 -0.106 0.278 0.704 0.1526 0.9 0.522 1.55 0.103 0.269 0.701 0.1542 1.11 0.654 1.88 0.166 0.265 0.532 0.274 1.18 0.702 1.99 PRS_PLINK_2.51188643150958e.06 FALSE 271 Disorders of carbohydrate transport and metabolism Both 1008 4492 3 endocrine/metabolic brown 4492, 1008 1122, 220 1123, 232 1123, 268 1123, 288 0.102 0.0369 0.00581 2.236 1.11 1.03 1.19 0.0432 0.103 0.676 0.1701 1.04 0.853 1.28 0.204 0.101 0.0419 1.378 1.23 1.01 1.49 0.274 0.0996 0.00593 2.227 1.32 1.08 1.6 PRS_PLINK_2.51188643150958e.06 FALSE 271.3 Intestinal disaccharidase deficiencies and disaccharide malabsorption Both 981 4394 3 endocrine/metabolic brown 4394, 981 1098, 212 1098, 226 1098, 262 1099, 281 0.105 0.0373 0.00478 2.32 1.11 1.03 1.2 0.0555 0.105 0.597 0.2238 1.06 0.86 1.3 0.22 0.102 0.0308 1.512 1.25 1.02 1.52 0.289 0.101 0.00428 2.368 1.33 1.09 1.63 PRS_PLINK_2.51188643150958e.06 FALSE 271.9 Other disorders of carbohydrate transport and metabolism Both 42 160 3 endocrine/metabolic brown 160, 42 40, 10 40, 10 40, 8 40, 14 0.256 0.215 0.233 0.6325 1.29 0.848 1.97 0.0278 0.508 0.956 0.01942 1.03 0.38 2.78 0.0679 0.582 0.907 0.04236 1.07 0.342 3.35 0.285 0.485 0.557 0.2538 1.33 0.514 3.44 PRS_PLINK_2.51188643150958e.06 TRUE 272 Disorders of lipoid metabolism Both 4585 2809 3 endocrine/metabolic brown 2809, 4585 703, 1095 702, 1158 702, 1222 702, 1109 0.0166 0.0267 0.534 0.2728 1.02 0.965 1.07 0.0398 0.0761 0.601 0.2212 1.04 0.896 1.21 0.149 0.076 0.0494 1.306 1.16 1 1.35 0.0225 0.0774 0.771 0.1127 1.02 0.879 1.19 PRS_PLINK_2.51188643150958e.06 FALSE 272.1 Hyperlipidemia Both 4573 2808 3 endocrine/metabolic brown 2808, 4573 702, 1096 702, 1150 702, 1219 702, 1107 0.016 0.0267 0.549 0.2601 1.02 0.964 1.07 0.0279 0.0762 0.714 0.1463 1.03 0.886 1.19 0.142 0.076 0.0616 1.21 1.15 0.993 1.34 0.0175 0.0774 0.821 0.08579 1.02 0.874 1.18 PRS_PLINK_2.51188643150958e.06 FALSE 272.11 Hypercholesterolemia Both 1764 2330 3 endocrine/metabolic brown 2330, 1764 583, 442 582, 430 582, 458 583, 434 0.0283 0.0355 0.425 0.3717 1.03 0.96 1.1 0.00674 0.101 0.947 0.02383 1.01 0.827 1.23 0.146 0.0997 0.143 0.8448 1.16 0.952 1.41 0.0257 0.102 0.8 0.09667 1.03 0.841 1.25 PRS_PLINK_2.51188643150958e.06 FALSE 272.12 Hyperglyceridemia Both 504 1229 3 endocrine/metabolic brown 1229, 504 308, 124 307, 122 307, 146 307, 112 -0.0128 0.0546 0.814 0.08941 0.987 0.887 1.1 0.0432 0.159 0.785 0.1051 1.04 0.765 1.42 0.201 0.155 0.195 0.7102 1.22 0.902 1.66 -0.097 0.161 0.547 0.2618 0.908 0.662 1.24 PRS_PLINK_2.51188643150958e.06 FALSE 272.13 Mixed hyperlipidemia Both 1264 1979 3 endocrine/metabolic brown 1979, 1264 495, 293 495, 314 494, 347 495, 310 0.0285 0.0403 0.478 0.3203 1.03 0.951 1.11 0.0791 0.113 0.485 0.3143 1.08 0.867 1.35 0.233 0.114 0.0408 1.389 1.26 1.01 1.58 0.0776 0.116 0.504 0.298 1.08 0.861 1.36 PRS_PLINK_2.51188643150958e.06 FALSE 272.9 Unspecified disorder of lipoid metabolism Both 118 344 3 endocrine/metabolic brown 344, 118 86, 29 86, 32 86, 29 86, 28 -0.039 0.11 0.724 0.1402 0.962 0.775 1.19 0.267 0.322 0.408 0.3892 1.31 0.694 2.46 0.0759 0.321 0.813 0.08982 1.08 0.575 2.02 0.0488 0.316 0.878 0.05675 1.05 0.565 1.95 PRS_PLINK_2.51188643150958e.06 FALSE 274 Gout and other crystal arthropathies Both 789 3610 3 endocrine/metabolic brown 3610, 789 902, 179 902, 187 902, 226 903, 197 0.0538 0.0408 0.188 0.7269 1.06 0.974 1.14 0.0509 0.115 0.657 0.1822 1.05 0.84 1.32 0.249 0.111 0.0248 1.605 1.28 1.03 1.59 0.116 0.114 0.309 0.5107 1.12 0.898 1.4 PRS_PLINK_2.51188643150958e.06 FALSE 274.1 Gout Both 743 3482 3 endocrine/metabolic brown 3482, 743 870, 172 870, 167 870, 214 871, 190 0.0529 0.042 0.207 0.6836 1.05 0.971 1.14 -0.0246 0.119 0.836 0.07766 0.976 0.773 1.23 0.235 0.113 0.0384 1.416 1.26 1.01 1.58 0.118 0.116 0.309 0.51 1.13 0.896 1.41 PRS_PLINK_2.51188643150958e.06 FALSE 274.11 Gouty arthropathy Both 439 1738 3 endocrine/metabolic brown 1738, 439 434, 98 434, 94 434, 143 435, 104 0.0111 0.0524 0.832 0.07982 1.01 0.913 1.12 -0.0233 0.16 0.884 0.05357 0.977 0.714 1.34 0.372 0.148 0.0119 1.925 1.45 1.09 1.94 0.0546 0.157 0.728 0.1381 1.06 0.777 1.44 PRS_PLINK_2.51188643150958e.06 FALSE 274.2 Crystal arthropathies Both 90 352 3 endocrine/metabolic brown 352, 90 88, 18 88, 26 88, 28 88, 18 0.0763 0.139 0.584 0.2339 1.08 0.822 1.42 0.389 0.346 0.262 0.5819 1.48 0.748 2.91 0.432 0.35 0.217 0.6634 1.54 0.776 3.06 -0.0618 0.366 0.866 0.0625 0.94 0.459 1.93 PRS_PLINK_2.51188643150958e.06 FALSE 274.21 Chondrocalcinosis Both 83 323 3 endocrine/metabolic brown 323, 83 81, 15 81, 24 80, 27 81, 17 0.128 0.141 0.364 0.439 1.14 0.862 1.5 0.655 0.382 0.0862 1.065 1.93 0.911 4.07 0.589 0.371 0.113 0.9482 1.8 0.87 3.73 0.148 0.387 0.702 0.154 1.16 0.543 2.48 PRS_PLINK_2.51188643150958e.06 FALSE 275 Disorders of mineral metabolism Both 1595 5346 3 endocrine/metabolic brown 5346, 1595 1337, 393 1336, 399 1336, 420 1337, 382 0.0149 0.0288 0.606 0.2175 1.01 0.959 1.07 0.012 0.0811 0.883 0.05418 1.01 0.863 1.19 0.0684 0.0804 0.395 0.4032 1.07 0.915 1.25 -0.0255 0.082 0.756 0.1214 0.975 0.83 1.14 PRS_PLINK_2.51188643150958e.06 FALSE 275.1 Disorders of iron metabolism Both 98 331 4 hematopoietic darkorange1 331, 98 83, 18 83, 31 82, 21 83, 28 0.0921 0.115 0.425 0.3719 1.1 0.875 1.37 0.542 0.337 0.108 0.968 1.72 0.888 3.33 0.217 0.365 0.552 0.2577 1.24 0.608 2.54 0.473 0.352 0.179 0.7461 1.6 0.805 3.2 PRS_PLINK_2.51188643150958e.06 FALSE 275.11 Hereditary hemochromatosis Both 29 141 4 hematopoietic darkorange1 141, 29 36, 7 35, 9 35, 4 35, 9 0.0673 0.228 0.768 0.1147 1.07 0.684 1.67 0.0651 0.562 0.908 0.04199 1.07 0.355 3.21 -0.675 0.669 0.313 0.5042 0.509 0.137 1.89 -0.0843 0.569 0.882 0.05441 0.919 0.301 2.8 PRS_PLINK_2.51188643150958e.06 TRUE 275.2 Disorders of copper metabolism Both 34 89 3 endocrine/metabolic brown 89, 34 23, 15 22, 12 22, 5 22, 2 -0.372 0.202 0.0656 1.183 0.689 0.464 1.02 -0.462 0.563 0.412 0.3851 0.63 0.209 1.9 -1.06 0.685 0.121 0.9184 0.345 0.0902 1.32 -2.28 0.89 0.0103 1.986 0.102 0.0178 0.584 PRS_PLINK_2.51188643150958e.06 TRUE 275.3 Disorders of magnesium metabolism Both 483 1728 3 endocrine/metabolic brown 1728, 483 432, 125 432, 111 432, 125 432, 122 0.0439 0.0536 0.413 0.3839 1.04 0.941 1.16 -0.0864 0.149 0.561 0.2512 0.917 0.686 1.23 0.0335 0.146 0.818 0.08715 1.03 0.777 1.38 -0.0121 0.146 0.934 0.02953 0.988 0.742 1.32 PRS_PLINK_2.51188643150958e.06 FALSE 275.5 Disorders of calcium/phosphorus metabolism Both 1215 4626 3 endocrine/metabolic brown 4626, 1215 1157, 297 1156, 291 1156, 331 1157, 295 0.0336 0.0326 0.302 0.5196 1.03 0.97 1.1 -0.0164 0.0925 0.859 0.06605 0.984 0.821 1.18 0.105 0.0903 0.245 0.6107 1.11 0.931 1.33 -0.00639 0.0923 0.945 0.02466 0.994 0.829 1.19 PRS_PLINK_2.51188643150958e.06 FALSE 275.51 Hypocalcemia Both 317 1340 3 endocrine/metabolic brown 1340, 317 335, 83 335, 71 335, 93 335, 70 0.0304 0.0627 0.628 0.2019 1.03 0.912 1.17 -0.1 0.181 0.579 0.2375 0.905 0.635 1.29 0.101 0.171 0.555 0.2557 1.11 0.792 1.54 -0.134 0.181 0.459 0.338 0.875 0.613 1.25 PRS_PLINK_2.51188643150958e.06 FALSE 275.53 Disorders of phosphorus metabolism Both 554 1962 3 endocrine/metabolic brown 1962, 554 491, 143 490, 128 490, 148 491, 134 0.0279 0.0485 0.564 0.2484 1.03 0.935 1.13 -0.0938 0.138 0.498 0.3026 0.911 0.694 1.19 0.031 0.134 0.817 0.08762 1.03 0.793 1.34 -0.0704 0.137 0.607 0.2165 0.932 0.712 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 275.6 Hypercalcemia Both 522 2268 3 endocrine/metabolic brown 2268, 522 567, 118 567, 129 567, 148 567, 127 0.0385 0.0496 0.438 0.3587 1.04 0.943 1.15 0.0932 0.141 0.508 0.294 1.1 0.833 1.45 0.233 0.138 0.0922 1.035 1.26 0.963 1.66 0.0607 0.141 0.668 0.1753 1.06 0.805 1.4 PRS_PLINK_2.51188643150958e.06 FALSE 276 Disorders of fluid, electrolyte, and acid-base balance Both 3182 4208 3 endocrine/metabolic brown 4208, 3182 1052, 788 1052, 736 1052, 838 1052, 819 0.0417 0.024 0.0828 1.082 1.04 0.995 1.09 -0.0824 0.0688 0.231 0.6361 0.921 0.805 1.05 0.057 0.0676 0.399 0.3987 1.06 0.927 1.21 0.0428 0.0676 0.527 0.2785 1.04 0.914 1.19 PRS_PLINK_2.51188643150958e.06 FALSE 276.1 Electrolyte imbalance Both 2331 4000 3 endocrine/metabolic brown 4000, 2331 1000, 583 1000, 541 1000, 610 1000, 596 0.0342 0.0267 0.2 0.6983 1.03 0.982 1.09 -0.0798 0.0763 0.296 0.5293 0.923 0.795 1.07 0.0576 0.075 0.442 0.3543 1.06 0.914 1.23 0.0236 0.0752 0.754 0.1229 1.02 0.884 1.19 PRS_PLINK_2.51188643150958e.06 FALSE 276.11 Hyperosmolality and/or hypernatremia Both 223 721 3 endocrine/metabolic brown 721, 223 181, 68 180, 41 180, 57 180, 56 -0.0199 0.0763 0.795 0.09976 0.98 0.844 1.14 -0.48 0.225 0.033 1.482 0.619 0.398 0.962 -0.145 0.211 0.492 0.3084 0.865 0.572 1.31 -0.197 0.212 0.353 0.4525 0.821 0.542 1.24 PRS_PLINK_2.51188643150958e.06 FALSE 276.12 Hyposmolality and/or hyponatremia Both 932 2738 3 endocrine/metabolic brown 2738, 932 685, 231 684, 210 684, 236 685, 255 0.0515 0.0399 0.197 0.7057 1.05 0.974 1.14 -0.0763 0.11 0.49 0.3101 0.927 0.746 1.15 0.0357 0.108 0.741 0.1302 1.04 0.839 1.28 0.1 0.107 0.346 0.4613 1.11 0.897 1.36 PRS_PLINK_2.51188643150958e.06 FALSE 276.13 Hyperpotassemia Both 1185 2980 3 endocrine/metabolic brown 2980, 1185 745, 290 745, 286 745, 313 745, 296 0.0204 0.0354 0.565 0.2478 1.02 0.952 1.09 -0.011 0.099 0.911 0.04031 0.989 0.815 1.2 0.0772 0.0974 0.428 0.3685 1.08 0.893 1.31 0.0241 0.0985 0.807 0.0933 1.02 0.845 1.24 PRS_PLINK_2.51188643150958e.06 FALSE 276.14 Hypopotassemia Both 920 2576 3 endocrine/metabolic brown 2576, 920 644, 221 644, 221 644, 250 644, 227 0.032 0.039 0.412 0.3851 1.03 0.957 1.11 -0.00119 0.111 0.991 0.003731 0.999 0.804 1.24 0.112 0.109 0.301 0.5213 1.12 0.904 1.38 0.0255 0.11 0.817 0.08786 1.03 0.827 1.27 PRS_PLINK_2.51188643150958e.06 FALSE 276.4 Acid-base balance disorder Both 841 2428 3 endocrine/metabolic brown 2428, 841 607, 225 607, 193 607, 198 607, 224 0.0151 0.0402 0.707 0.1506 1.02 0.938 1.1 -0.146 0.114 0.201 0.6959 0.864 0.691 1.08 -0.117 0.114 0.306 0.515 0.89 0.712 1.11 -0.00271 0.112 0.981 0.008489 0.997 0.801 1.24 PRS_PLINK_2.51188643150958e.06 FALSE 276.41 Acidosis Both 726 2096 3 endocrine/metabolic brown 2096, 726 524, 194 524, 169 524, 176 524, 186 0.00266 0.0432 0.951 0.02188 1 0.921 1.09 -0.136 0.123 0.268 0.5712 0.873 0.686 1.11 -0.0812 0.122 0.507 0.2951 0.922 0.726 1.17 -0.0272 0.122 0.823 0.08461 0.973 0.767 1.24 PRS_PLINK_2.51188643150958e.06 FALSE 276.42 Alkalosis Both 220 607 3 endocrine/metabolic brown 607, 220 152, 60 152, 53 151, 45 152, 62 0.0376 0.0785 0.632 0.1996 1.04 0.89 1.21 -0.0682 0.225 0.762 0.1182 0.934 0.601 1.45 -0.285 0.231 0.217 0.663 0.752 0.478 1.18 0.0937 0.218 0.667 0.1758 1.1 0.716 1.68 PRS_PLINK_2.51188643150958e.06 FALSE 276.5 Hypovolemia Both 1770 3993 3 endocrine/metabolic brown 3993, 1770 999, 431 998, 396 998, 493 998, 449 0.0563 0.0293 0.0546 1.263 1.06 0.999 1.12 -0.0905 0.0835 0.278 0.5559 0.913 0.776 1.08 0.128 0.0806 0.113 0.9452 1.14 0.97 1.33 0.0456 0.0816 0.576 0.2393 1.05 0.892 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 276.6 Fluid overload Both 597 1617 3 endocrine/metabolic brown 1617, 597 405, 161 404, 117 404, 157 404, 161 0.0198 0.0482 0.681 0.167 1.02 0.928 1.12 -0.303 0.14 0.0311 1.507 0.739 0.561 0.973 0.0104 0.134 0.938 0.02765 1.01 0.777 1.31 -0.0167 0.133 0.9 0.04561 0.983 0.757 1.28 PRS_PLINK_2.51188643150958e.06 FALSE 276.8 Polydipsia Both 57 148 3 endocrine/metabolic brown 148, 57 37, 17 37, 16 37, 17 37, 7 -0.175 0.167 0.296 0.5294 0.84 0.605 1.17 -0.156 0.437 0.721 0.142 0.855 0.363 2.02 -0.0461 0.467 0.921 0.03558 0.955 0.383 2.38 -0.985 0.543 0.0693 1.159 0.373 0.129 1.08 PRS_PLINK_2.51188643150958e.06 FALSE 277 Other disorders of metabolism Both 1573 4934 3 endocrine/metabolic brown 4934, 1573 1233, 420 1233, 369 1233, 393 1234, 391 -0.0192 0.0292 0.51 0.2924 0.981 0.926 1.04 -0.124 0.0824 0.133 0.8772 0.883 0.752 1.04 -0.063 0.0813 0.439 0.3578 0.939 0.801 1.1 -0.079 0.0817 0.333 0.477 0.924 0.787 1.08 PRS_PLINK_2.51188643150958e.06 FALSE 277.2 Other disorders of purine and pyrimidine metabolism Both 165 680 3 endocrine/metabolic brown 680, 165 170, 36 170, 39 170, 45 170, 45 0.0587 0.086 0.495 0.3057 1.06 0.896 1.26 0.17 0.261 0.514 0.2889 1.19 0.711 1.98 0.251 0.255 0.325 0.488 1.29 0.78 2.12 0.239 0.254 0.347 0.4599 1.27 0.772 2.09 PRS_PLINK_2.51188643150958e.06 FALSE 277.4 Disorders of bilirubin excretion Both 247 978 3 endocrine/metabolic brown 978, 247 245, 62 244, 53 244, 60 245, 72 0.0405 0.0701 0.563 0.2493 1.04 0.908 1.19 -0.141 0.21 0.503 0.2986 0.869 0.575 1.31 -0.0413 0.204 0.84 0.07588 0.96 0.643 1.43 0.144 0.197 0.465 0.3322 1.15 0.785 1.7 PRS_PLINK_2.51188643150958e.06 FALSE 277.5 Other disorders of lipoid metabolism Both 335 1389 3 endocrine/metabolic brown 1389, 335 348, 97 347, 82 347, 69 347, 87 -0.00805 0.0621 0.897 0.04729 0.992 0.878 1.12 -0.153 0.169 0.364 0.4387 0.858 0.616 1.19 -0.339 0.176 0.0544 1.265 0.712 0.504 1.01 -0.111 0.167 0.506 0.2957 0.895 0.645 1.24 PRS_PLINK_2.51188643150958e.06 FALSE 277.51 Lipoprotein disorders Both 285 1142 3 endocrine/metabolic brown 1142, 285 286, 81 285, 74 285, 61 286, 69 -0.0409 0.0669 0.541 0.2668 0.96 0.842 1.09 -0.079 0.183 0.666 0.1768 0.924 0.646 1.32 -0.27 0.191 0.158 0.8005 0.764 0.525 1.11 -0.165 0.186 0.376 0.4248 0.848 0.589 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 277.7 Dysmetabolic syndrome X Both 436 1371 3 endocrine/metabolic brown 1371, 436 343, 108 343, 101 342, 118 343, 109 -0.0443 0.0553 0.422 0.3743 0.957 0.858 1.07 -0.0966 0.16 0.545 0.2638 0.908 0.664 1.24 0.0512 0.155 0.741 0.1302 1.05 0.777 1.43 -0.0052 0.157 0.974 0.01161 0.995 0.731 1.35 PRS_PLINK_2.51188643150958e.06 FALSE 278 Overweight, obesity and other hyperalimentation Both 4369 3076 3 endocrine/metabolic brown 3076, 4369 769, 1091 769, 1037 769, 1150 769, 1090 0.00397 0.0237 0.867 0.06187 1 0.958 1.05 -0.0538 0.0676 0.427 0.3699 0.948 0.83 1.08 0.0579 0.067 0.387 0.4119 1.06 0.929 1.21 -0.013 0.0675 0.847 0.07224 0.987 0.865 1.13 PRS_PLINK_2.51188643150958e.06 FALSE 278.1 Obesity Both 3805 3076 3 endocrine/metabolic brown 3076, 3805 769, 947 769, 900 769, 997 769, 961 0.0136 0.0246 0.581 0.236 1.01 0.966 1.06 -0.0531 0.0699 0.448 0.3491 0.948 0.827 1.09 0.0595 0.0692 0.39 0.4093 1.06 0.927 1.22 0.00354 0.0696 0.959 0.01797 1 0.876 1.15 PRS_PLINK_2.51188643150958e.06 FALSE 278.11 Morbid obesity Both 2233 3068 3 endocrine/metabolic brown 3068, 2233 767, 570 767, 524 767, 555 767, 584 -0.00603 0.0279 0.829 0.08146 0.994 0.941 1.05 -0.0873 0.0813 0.283 0.5487 0.916 0.781 1.07 -0.0354 0.0807 0.661 0.1796 0.965 0.824 1.13 0.0127 0.0802 0.874 0.05827 1.01 0.866 1.19 PRS_PLINK_2.51188643150958e.06 FALSE 278.3 Localized adiposity Both 152 390 3 endocrine/metabolic brown 390, 152 98, 34 97, 22 97, 43 98, 53 0.193 0.103 0.0616 1.21 1.21 0.991 1.49 -0.48 0.316 0.129 0.8884 0.619 0.333 1.15 0.245 0.278 0.378 0.4225 1.28 0.741 2.2 0.427 0.27 0.114 0.9416 1.53 0.902 2.6 PRS_PLINK_2.51188643150958e.06 FALSE 278.4 Abnormal weight gain Both 890 2007 3 endocrine/metabolic brown 2007, 890 502, 197 502, 209 501, 256 502, 228 0.0304 0.0404 0.451 0.3454 1.03 0.952 1.12 0.0699 0.119 0.556 0.2548 1.07 0.85 1.35 0.264 0.115 0.0221 1.656 1.3 1.04 1.63 0.128 0.117 0.275 0.5604 1.14 0.903 1.43 PRS_PLINK_2.51188643150958e.06 FALSE 279 Disorders involving the immune mechanism Both 1267 3496 3 endocrine/metabolic brown 3496, 1267 873, 301 874, 291 874, 344 874, 331 0.0673 0.0334 0.0443 1.354 1.07 1 1.14 -0.0162 0.0957 0.865 0.06287 0.984 0.816 1.19 0.141 0.0929 0.129 0.889 1.15 0.96 1.38 0.105 0.094 0.262 0.5814 1.11 0.924 1.34 PRS_PLINK_2.51188643150958e.06 FALSE 279.1 Immunity deficiency Both 509 1402 3 endocrine/metabolic brown 1402, 509 351, 121 350, 123 350, 155 351, 110 0.0435 0.0525 0.407 0.3909 1.04 0.942 1.16 0.0376 0.15 0.802 0.0957 1.04 0.774 1.39 0.264 0.144 0.0673 1.172 1.3 0.981 1.73 -0.0663 0.154 0.667 0.1758 0.936 0.692 1.27 PRS_PLINK_2.51188643150958e.06 FALSE 279.11 Deficiency of humoral immunity Both 171 404 3 endocrine/metabolic brown 404, 171 101, 48 101, 39 101, 49 101, 35 0.00457 0.0939 0.961 0.01718 1 0.836 1.21 -0.0951 0.269 0.724 0.1406 0.909 0.537 1.54 0.0681 0.258 0.792 0.1013 1.07 0.646 1.77 -0.33 0.269 0.219 0.6592 0.719 0.425 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 279.2 Autoimmune disease NEC Both 374 1016 3 endocrine/metabolic brown 1016, 374 254, 105 254, 77 254, 93 254, 99 -0.00341 0.0617 0.956 0.01955 0.997 0.883 1.12 -0.302 0.175 0.085 1.071 0.739 0.524 1.04 -0.103 0.169 0.544 0.2646 0.902 0.648 1.26 -0.0393 0.168 0.814 0.08913 0.961 0.692 1.34 PRS_PLINK_2.51188643150958e.06 FALSE 279.7 Other immunological findings Both 2206 4400 3 endocrine/metabolic brown 4400, 2206 1099, 550 1100, 536 1100, 535 1100, 585 0.0267 0.0263 0.31 0.5082 1.03 0.975 1.08 -0.0336 0.0749 0.654 0.1843 0.967 0.835 1.12 -0.026 0.0749 0.728 0.1379 0.974 0.841 1.13 0.0826 0.0738 0.263 0.5793 1.09 0.94 1.26 PRS_PLINK_2.51188643150958e.06 FALSE 279.8 Other specified disorders involving the immune mechanism Both 276 756 3 endocrine/metabolic brown 756, 276 188, 72 189, 57 189, 69 189, 78 0.0824 0.0709 0.246 0.6095 1.09 0.945 1.25 -0.237 0.206 0.25 0.6028 0.789 0.527 1.18 -0.044 0.202 0.827 0.08247 0.957 0.645 1.42 0.127 0.197 0.518 0.2859 1.14 0.772 1.67 PRS_PLINK_2.51188643150958e.06 FALSE 280 Iron deficiency anemias Both 2322 2881 4 hematopoietic darkorange1 2881, 2322 721, 565 720, 515 720, 635 720, 606 0.0443 0.0283 0.117 0.9312 1.05 0.989 1.1 -0.1 0.0813 0.219 0.6599 0.905 0.772 1.06 0.13 0.0791 0.1 0.9988 1.14 0.975 1.33 0.0979 0.0797 0.22 0.6583 1.1 0.943 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 280.1 Iron deficiency anemias, unspecified or not due to blood loss Both 2257 2870 4 hematopoietic darkorange1 2870, 2257 718, 547 717, 502 717, 614 718, 593 0.0456 0.0285 0.11 0.9596 1.05 0.99 1.11 -0.0934 0.0821 0.255 0.5928 0.911 0.775 1.07 0.13 0.0799 0.105 0.979 1.14 0.973 1.33 0.108 0.0804 0.179 0.7465 1.11 0.952 1.3 PRS_PLINK_2.51188643150958e.06 FALSE 280.2 Iron deficiency anemia secondary to blood loss (chronic) Both 952 1700 4 hematopoietic darkorange1 1700, 952 425, 239 425, 196 425, 270 425, 246 0.0123 0.0403 0.761 0.1186 1.01 0.935 1.1 -0.2 0.12 0.0938 1.028 0.818 0.648 1.03 0.116 0.114 0.306 0.5141 1.12 0.899 1.4 0.0298 0.116 0.797 0.09862 1.03 0.821 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 281 Other deficiency anemia Both 357 527 4 hematopoietic darkorange1 527, 357 132, 93 132, 75 131, 94 132, 95 -0.000396 0.0697 0.995 0.001976 1 0.872 1.15 -0.295 0.207 0.154 0.8133 0.745 0.496 1.12 0.0202 0.195 0.918 0.03728 1.02 0.696 1.5 -0.044 0.196 0.823 0.08473 0.957 0.651 1.41 PRS_PLINK_2.51188643150958e.06 FALSE 281.1 Megaloblastic anemia Both 173 264 4 hematopoietic darkorange1 264, 173 66, 43 66, 41 66, 49 66, 40 -0.031 0.103 0.764 0.117 0.97 0.792 1.19 -0.12 0.293 0.682 0.1659 0.887 0.499 1.58 0.202 0.283 0.476 0.3228 1.22 0.703 2.13 -0.207 0.295 0.484 0.3151 0.813 0.456 1.45 PRS_PLINK_2.51188643150958e.06 FALSE 281.11 Pernicious anemia Both 76 113 4 hematopoietic darkorange1 113, 76 29, 17 28, 24 28, 20 28, 15 -0.0125 0.155 0.936 0.02874 0.988 0.729 1.34 -0.0423 0.469 0.928 0.03239 0.959 0.382 2.4 0.255 0.469 0.586 0.2319 1.29 0.514 3.24 -0.293 0.493 0.553 0.2576 0.746 0.284 1.96 PRS_PLINK_2.51188643150958e.06 FALSE 281.12 Other vitamin B12 deficiency anemia Both 121 208 4 hematopoietic darkorange1 208, 121 52, 33 52, 31 52, 35 52, 22 -0.107 0.119 0.366 0.4363 0.898 0.712 1.13 -0.155 0.333 0.641 0.1929 0.856 0.446 1.65 0.176 0.329 0.593 0.2273 1.19 0.626 2.27 -0.519 0.358 0.147 0.8324 0.595 0.295 1.2 PRS_PLINK_2.51188643150958e.06 FALSE 281.9 Deficiency anemias Both 208 289 4 hematopoietic darkorange1 289, 208 73, 54 72, 37 72, 55 72, 62 -0.0327 0.0942 0.729 0.1376 0.968 0.805 1.16 -0.501 0.288 0.0818 1.087 0.606 0.345 1.07 0.042 0.264 0.873 0.05881 1.04 0.622 1.75 0.0111 0.262 0.966 0.01489 1.01 0.605 1.69 PRS_PLINK_2.51188643150958e.06 FALSE 282 Hereditary hemolytic anemias Both 114 302 4 hematopoietic darkorange1 302, 114 76, 18 75, 19 75, 32 76, 45 0.389 0.136 0.0041 2.387 1.48 1.13 1.93 -0.0855 0.37 0.817 0.08755 0.918 0.444 1.9 0.562 0.354 0.113 0.9475 1.75 0.876 3.51 0.849 0.327 0.00944 2.025 2.34 1.23 4.43 PRS_PLINK_2.51188643150958e.06 FALSE 282.8 Other hemoglobinopathies Both 70 208 4 hematopoietic darkorange1 208, 70 52, 9 52, 11 52, 20 52, 30 0.776 0.206 0.000172 3.764 2.17 1.45 3.26 -0.211 0.502 0.674 0.1711 0.81 0.303 2.17 0.601 0.466 0.198 0.7039 1.82 0.731 4.55 1.18 0.455 0.00964 2.016 3.25 1.33 7.92 PRS_PLINK_2.51188643150958e.06 FALSE 282.9 Other hereditary hemolytic anemias Both 79 176 4 hematopoietic darkorange1 176, 79 44, 13 44, 10 44, 24 44, 32 0.41 0.172 0.0173 1.762 1.51 1.08 2.11 -0.364 0.489 0.457 0.3399 0.695 0.266 1.81 0.687 0.433 0.112 0.9494 1.99 0.851 4.64 1.08 0.423 0.0106 1.975 2.95 1.29 6.76 PRS_PLINK_2.51188643150958e.06 FALSE 283 Acquired hemolytic anemias Both 78 158 4 hematopoietic darkorange1 158, 78 40, 16 39, 16 39, 26 40, 20 0.156 0.151 0.302 0.5196 1.17 0.869 1.57 0.0407 0.449 0.928 0.03259 1.04 0.432 2.51 0.641 0.42 0.127 0.8973 1.9 0.834 4.32 0.284 0.427 0.506 0.2959 1.33 0.576 3.06 PRS_PLINK_2.51188643150958e.06 FALSE 283.1 Autoimmune hemolytic anemias Both 34 67 4 hematopoietic darkorange1 67, 34 17, 14 17, 2 16, 8 17, 10 -0.109 0.218 0.617 0.2098 0.897 0.585 1.37 -2 0.872 0.0215 1.667 0.135 0.0244 0.744 -0.469 0.639 0.463 0.3342 0.626 0.179 2.19 -0.0702 0.619 0.91 0.0411 0.932 0.277 3.13 PRS_PLINK_2.51188643150958e.06 TRUE 284 Aplastic anemia Both 341 679 4 hematopoietic darkorange1 679, 341 170, 85 170, 72 169, 94 170, 90 0.0609 0.0732 0.405 0.3922 1.06 0.921 1.23 -0.15 0.195 0.441 0.3556 0.86 0.587 1.26 0.0899 0.188 0.633 0.1986 1.09 0.756 1.58 0.0158 0.191 0.934 0.02962 1.02 0.699 1.48 PRS_PLINK_2.51188643150958e.06 FALSE 284.1 Pancytopenia Both 290 612 4 hematopoietic darkorange1 612, 290 153, 68 153, 66 153, 79 153, 77 0.0688 0.0772 0.373 0.4281 1.07 0.921 1.25 -0.0183 0.21 0.93 0.03136 0.982 0.651 1.48 0.128 0.205 0.535 0.272 1.14 0.76 1.7 0.0881 0.207 0.671 0.1734 1.09 0.728 1.64 PRS_PLINK_2.51188643150958e.06 FALSE 285 Other anemias Both 4036 3028 4 hematopoietic darkorange1 3028, 4036 757, 995 757, 948 757, 1050 757, 1042 0.0212 0.0242 0.379 0.4209 1.02 0.974 1.07 -0.0589 0.0696 0.398 0.4005 0.943 0.823 1.08 0.0549 0.069 0.426 0.3707 1.06 0.923 1.21 0.0601 0.069 0.384 0.4161 1.06 0.928 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 285.1 Acute posthemorrhagic anemia Both 1040 2579 4 hematopoietic darkorange1 2579, 1040 645, 257 645, 242 644, 254 645, 286 0.0386 0.0375 0.303 0.5187 1.04 0.966 1.12 -0.0626 0.107 0.558 0.2536 0.939 0.762 1.16 -0.00379 0.106 0.971 0.01256 0.996 0.809 1.23 0.118 0.104 0.257 0.5899 1.13 0.918 1.38 PRS_PLINK_2.51188643150958e.06 FALSE 285.2 Anemia of chronic disease Both 942 1963 4 hematopoietic darkorange1 1963, 942 491, 218 491, 212 490, 278 491, 233 0.0219 0.0403 0.587 0.2316 1.02 0.945 1.11 -0.0371 0.116 0.75 0.1251 0.964 0.767 1.21 0.226 0.112 0.0437 1.36 1.25 1.01 1.56 0.0264 0.116 0.82 0.08629 1.03 0.818 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 285.21 Anemia in chronic kidney disease Both 460 952 4 hematopoietic darkorange1 952, 460 238, 114 238, 96 238, 146 238, 104 -0.0103 0.0584 0.86 0.06526 0.99 0.883 1.11 -0.156 0.168 0.356 0.4488 0.856 0.615 1.19 0.237 0.157 0.131 0.8813 1.27 0.931 1.73 -0.105 0.168 0.533 0.2736 0.901 0.648 1.25 PRS_PLINK_2.51188643150958e.06 FALSE 285.22 Anemia in neoplastic disease Both 233 644 4 hematopoietic darkorange1 644, 233 161, 47 161, 59 161, 74 161, 53 0.106 0.0825 0.198 0.7035 1.11 0.946 1.31 0.289 0.228 0.206 0.6862 1.33 0.853 2.09 0.421 0.222 0.0581 1.235 1.52 0.986 2.35 0.0424 0.235 0.857 0.0671 1.04 0.658 1.65 PRS_PLINK_2.51188643150958e.06 FALSE 286 Coagulation defects Both 1354 4513 4 hematopoietic darkorange1 4513, 1354 1129, 365 1128, 292 1128, 359 1128, 337 -0.0197 0.0307 0.521 0.2833 0.98 0.923 1.04 -0.22 0.0897 0.0141 1.85 0.803 0.673 0.957 -0.0118 0.0861 0.891 0.05009 0.988 0.835 1.17 -0.0852 0.0873 0.329 0.4823 0.918 0.774 1.09 PRS_PLINK_2.51188643150958e.06 FALSE 286.1 Congenital coagulation defects Both 78 348 4 hematopoietic darkorange1 348, 78 87, 25 87, 13 87, 20 87, 20 0.04 0.12 0.738 0.1318 1.04 0.823 1.32 -0.653 0.373 0.0802 1.096 0.52 0.25 1.08 -0.277 0.341 0.417 0.3799 0.758 0.389 1.48 -0.177 0.34 0.603 0.2196 0.838 0.431 1.63 PRS_PLINK_2.51188643150958e.06 FALSE 286.11 Von willebrand's disease Both 30 126 4 hematopoietic darkorange1 126, 30 32, 7 31, 9 31, 7 32, 7 0.0986 0.199 0.621 0.2071 1.1 0.747 1.63 0.206 0.576 0.721 0.1421 1.23 0.397 3.8 0.0855 0.617 0.89 0.05078 1.09 0.325 3.65 0.135 0.589 0.819 0.0865 1.14 0.36 3.63 PRS_PLINK_2.51188643150958e.06 TRUE 286.12 Congenital deficiency of other clotting factors (including factor VII) Both 37 171 4 hematopoietic darkorange1 171, 37 43, 13 43, 4 42, 11 43, 9 -0.0372 0.174 0.83 0.08091 0.963 0.686 1.35 -1.21 0.624 0.0523 1.282 0.298 0.0877 1.01 -0.312 0.477 0.513 0.2898 0.732 0.287 1.86 -0.364 0.495 0.462 0.335 0.695 0.263 1.83 PRS_PLINK_2.51188643150958e.06 TRUE 286.2 Encounter for long-term (current) use of anticoagulants Both 1152 3491 4 hematopoietic darkorange1 3491, 1152 873, 313 873, 238 872, 312 873, 288 -0.0111 0.0346 0.747 0.1265 0.989 0.924 1.06 -0.273 0.1 0.00634 2.198 0.761 0.625 0.926 0.00666 0.0951 0.944 0.02495 1.01 0.835 1.21 -0.0989 0.0966 0.306 0.514 0.906 0.75 1.09 PRS_PLINK_2.51188643150958e.06 FALSE 286.3 Coagulation defects complicating pregnancy or postpartum Female 17 131 4 hematopoietic darkorange1 131, 17 33, 4 33, 4 32, 3 33, 6 0.308 0.276 0.265 0.5771 1.36 0.792 2.34 -0.00864 0.712 0.99 0.00422 0.991 0.245 4.01 -0.0952 0.714 0.894 0.04875 0.909 0.225 3.68 0.405 0.646 0.531 0.275 1.5 0.423 5.32 PRS_PLINK_2.51188643150958e.06 TRUE 286.4 Acquired coagulation factor deficiency Both 109 355 4 hematopoietic darkorange1 355, 109 89, 27 89, 26 88, 30 89, 26 -0.038 0.115 0.741 0.1304 0.963 0.769 1.21 -0.0323 0.316 0.919 0.03683 0.968 0.521 1.8 0.101 0.311 0.745 0.128 1.11 0.601 2.04 0.0417 0.321 0.897 0.04739 1.04 0.556 1.96 PRS_PLINK_2.51188643150958e.06 FALSE 286.5 Hemorrhagic disorder due to intrinsic circulating anticoagulants Both 66 187 4 hematopoietic darkorange1 187, 66 47, 19 47, 13 46, 15 47, 19 -0.0606 0.157 0.7 0.1551 0.941 0.692 1.28 -0.411 0.423 0.331 0.4798 0.663 0.289 1.52 -0.223 0.422 0.596 0.2245 0.8 0.35 1.83 5.96e-05 0.391 1 5.278e-05 1 0.464 2.15 PRS_PLINK_2.51188643150958e.06 FALSE 286.6 Defibrination syndrome Both 878 3499 4 hematopoietic darkorange1 3499, 878 875, 247 875, 185 874, 224 875, 222 -0.0305 0.0368 0.407 0.3904 0.97 0.903 1.04 -0.283 0.109 0.00934 2.03 0.754 0.609 0.933 -0.103 0.104 0.324 0.4897 0.902 0.735 1.11 -0.0989 0.105 0.345 0.4623 0.906 0.738 1.11 PRS_PLINK_2.51188643150958e.06 FALSE 286.7 Other and unspecified coagulation defects Both 1058 3980 4 hematopoietic darkorange1 3980, 1058 995, 288 995, 234 995, 262 995, 274 -0.0221 0.034 0.516 0.2876 0.978 0.915 1.05 -0.202 0.0991 0.0415 1.382 0.817 0.673 0.992 -0.0921 0.0968 0.341 0.4668 0.912 0.754 1.1 -0.0485 0.096 0.614 0.2122 0.953 0.789 1.15 PRS_PLINK_2.51188643150958e.06 FALSE 286.8 Hypercoagulable state Both 295 1201 4 hematopoietic darkorange1 1201, 295 301, 67 300, 70 300, 86 300, 72 0.079 0.068 0.245 0.61 1.08 0.947 1.24 0.0465 0.191 0.807 0.09296 1.05 0.721 1.52 0.239 0.185 0.194 0.7111 1.27 0.885 1.82 0.0786 0.189 0.678 0.1689 1.08 0.747 1.57 PRS_PLINK_2.51188643150958e.06 FALSE 286.81 Primary hypercoagulable state Both 277 1144 4 hematopoietic darkorange1 1144, 277 286, 64 286, 67 286, 78 286, 68 0.0808 0.0693 0.243 0.6136 1.08 0.947 1.24 0.0497 0.195 0.799 0.0976 1.05 0.717 1.54 0.186 0.19 0.326 0.4871 1.2 0.831 1.75 0.0641 0.194 0.741 0.13 1.07 0.729 1.56 PRS_PLINK_2.51188643150958e.06 FALSE 286.9 Abnormal coagulation profile Both 532 1665 4 hematopoietic darkorange1 1665, 532 417, 149 416, 104 416, 142 416, 136 0.0142 0.0506 0.779 0.1082 1.01 0.918 1.12 -0.324 0.146 0.0271 1.567 0.724 0.543 0.964 -0.0174 0.138 0.899 0.04602 0.983 0.75 1.29 -0.0692 0.139 0.619 0.2085 0.933 0.71 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 287 Purpura and other hemorrhagic conditions Both 1132 3800 4 hematopoietic darkorange1 3800, 1132 950, 277 950, 277 950, 297 950, 280 0.00211 0.0346 0.951 0.02171 1 0.936 1.07 0.0056 0.0973 0.954 0.02039 1.01 0.831 1.22 0.0663 0.0963 0.491 0.3087 1.07 0.885 1.29 0.00669 0.0976 0.945 0.02441 1.01 0.831 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 287.1 Spontaneous ecchymoses Both 103 299 4 hematopoietic darkorange1 299, 103 75, 30 75, 18 74, 23 75, 32 0.0747 0.113 0.511 0.2919 1.08 0.863 1.35 -0.484 0.353 0.17 0.7686 0.617 0.309 1.23 -0.25 0.34 0.462 0.3349 0.779 0.401 1.52 0.0587 0.324 0.856 0.06738 1.06 0.562 2 PRS_PLINK_2.51188643150958e.06 FALSE 287.3 Thrombocytopenia Both 1019 3507 4 hematopoietic darkorange1 3507, 1019 877, 248 877, 249 876, 274 877, 247 -0.00943 0.0362 0.795 0.09987 0.991 0.923 1.06 0.0197 0.102 0.847 0.07196 1.02 0.834 1.25 0.101 0.101 0.314 0.5033 1.11 0.909 1.35 -0.00534 0.103 0.959 0.01835 0.995 0.813 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 287.31 Primary thrombocytopenia Both 210 821 4 hematopoietic darkorange1 821, 210 206, 64 205, 45 205, 42 205, 59 -0.0568 0.0764 0.458 0.3395 0.945 0.813 1.1 -0.335 0.222 0.132 0.8791 0.715 0.462 1.11 -0.46 0.223 0.0396 1.403 0.631 0.408 0.978 -0.14 0.21 0.505 0.2966 0.869 0.576 1.31 PRS_PLINK_2.51188643150958e.06 FALSE 287.32 Secondary thrombocytopenia Both 217 744 4 hematopoietic darkorange1 744, 217 186, 53 186, 37 186, 69 186, 58 0.0624 0.0819 0.446 0.3508 1.06 0.907 1.25 -0.371 0.241 0.124 0.9082 0.69 0.431 1.11 0.183 0.213 0.39 0.4092 1.2 0.791 1.82 0.0116 0.221 0.958 0.01856 1.01 0.655 1.56 PRS_PLINK_2.51188643150958e.06 FALSE 287.4 Qualitative platelet defects Both 41 159 4 hematopoietic darkorange1 159, 41 40, 12 40, 11 39, 8 40, 10 -0.303 0.185 0.1 0.9981 0.739 0.514 1.06 0.181 0.509 0.722 0.1414 1.2 0.442 3.25 -0.415 0.515 0.42 0.3765 0.66 0.24 1.81 -0.229 0.494 0.643 0.1921 0.795 0.302 2.09 PRS_PLINK_2.51188643150958e.06 TRUE 288 Diseases of white blood cells Both 1782 4356 4 hematopoietic darkorange1 4356, 1782 1088, 441 1089, 399 1089, 498 1089, 444 0.0248 0.0282 0.378 0.4223 1.03 0.97 1.08 -0.0968 0.0818 0.237 0.6261 0.908 0.773 1.07 0.126 0.0789 0.112 0.9525 1.13 0.971 1.32 0.00182 0.0806 0.982 0.007899 1 0.855 1.17 PRS_PLINK_2.51188643150958e.06 FALSE 288.1 Decreased white blood cell count Both 636 2023 4 hematopoietic darkorange1 2023, 636 505, 152 506, 142 505, 184 506, 158 0.016 0.0456 0.726 0.139 1.02 0.929 1.11 -0.048 0.134 0.72 0.1429 0.953 0.733 1.24 0.192 0.128 0.134 0.8744 1.21 0.943 1.56 0.0348 0.131 0.791 0.1018 1.04 0.801 1.34 PRS_PLINK_2.51188643150958e.06 FALSE 288.11 Neutropenia Both 427 1414 4 hematopoietic darkorange1 1414, 427 353, 96 353, 105 353, 115 354, 111 0.042 0.0577 0.467 0.3302 1.04 0.931 1.17 0.103 0.161 0.522 0.2823 1.11 0.809 1.52 0.166 0.16 0.298 0.5259 1.18 0.863 1.62 0.128 0.161 0.427 0.3699 1.14 0.829 1.56 PRS_PLINK_2.51188643150958e.06 FALSE 288.2 Elevated white blood cell count Both 1521 4239 4 hematopoietic darkorange1 4239, 1521 1059, 375 1060, 341 1059, 435 1060, 370 0.0206 0.0298 0.489 0.3107 1.02 0.963 1.08 -0.0886 0.087 0.308 0.5111 0.915 0.772 1.09 0.152 0.0834 0.0683 1.166 1.16 0.989 1.37 -0.0176 0.086 0.838 0.07682 0.983 0.83 1.16 PRS_PLINK_2.51188643150958e.06 FALSE 288.3 Eosinophilia Both 73 199 4 hematopoietic darkorange1 199, 73 50, 25 50, 22 49, 11 50, 15 -0.21 0.13 0.106 0.9758 0.81 0.628 1.05 -0.0385 0.37 0.917 0.03756 0.962 0.466 1.99 -0.552 0.436 0.206 0.6864 0.576 0.245 1.35 -0.349 0.405 0.389 0.4096 0.705 0.319 1.56 PRS_PLINK_2.51188643150958e.06 FALSE 289 Other diseases of blood and blood-forming organs Both 836 2306 4 hematopoietic darkorange1 2306, 836 576, 210 576, 185 576, 237 577, 204 0.0384 0.0402 0.339 0.4698 1.04 0.96 1.12 -0.126 0.118 0.284 0.5471 0.881 0.699 1.11 0.136 0.113 0.229 0.6398 1.15 0.918 1.43 -0.0325 0.116 0.78 0.1082 0.968 0.771 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 289.3 Personal history of diseases of blood and blood-forming organs Both 418 1166 4 hematopoietic darkorange1 1166, 418 292, 113 291, 85 291, 124 292, 96 -0.0249 0.0558 0.656 0.1834 0.975 0.874 1.09 -0.273 0.167 0.103 0.9881 0.761 0.548 1.06 0.0742 0.156 0.635 0.1971 1.08 0.793 1.46 -0.188 0.166 0.257 0.5905 0.828 0.598 1.15 PRS_PLINK_2.51188643150958e.06 FALSE 289.4 Lymphadenitis Both 1134 4168 4 hematopoietic darkorange1 4168, 1134 1041, 257 1042, 275 1042, 335 1042, 267 0.0288 0.0336 0.392 0.4066 1.03 0.964 1.1 0.0614 0.0975 0.529 0.2765 1.06 0.878 1.29 0.268 0.0941 0.00436 2.361 1.31 1.09 1.57 0.0244 0.0983 0.804 0.09466 1.02 0.845 1.24 PRS_PLINK_2.51188643150958e.06 FALSE 289.5 Diseases of spleen Both 167 504 4 hematopoietic darkorange1 504, 167 126, 42 126, 45 126, 49 126, 31 -0.0472 0.0892 0.597 0.2243 0.954 0.801 1.14 0.113 0.254 0.657 0.1825 1.12 0.68 1.84 0.168 0.247 0.497 0.3034 1.18 0.729 1.92 -0.312 0.272 0.25 0.6021 0.732 0.43 1.25 PRS_PLINK_2.51188643150958e.06 FALSE 289.8 Polycythemia, secondary Both 91 312 4 hematopoietic darkorange1 312, 91 78, 15 78, 24 78, 30 78, 22 0.444 0.153 0.0038 2.421 1.56 1.15 2.1 0.721 0.396 0.0688 1.162 2.06 0.946 4.47 0.758 0.368 0.0397 1.401 2.13 1.04 4.39 0.337 0.378 0.373 0.4288 1.4 0.668 2.94 PRS_PLINK_2.51188643150958e.06 FALSE 289.9 Abnormality of red blood cells Both 190 512 4 hematopoietic darkorange1 512, 190 127, 35 128, 47 128, 51 128, 57 0.204 0.0935 0.0294 1.531 1.23 1.02 1.47 0.275 0.264 0.297 0.5266 1.32 0.785 2.21 0.374 0.259 0.149 0.8281 1.45 0.875 2.41 0.473 0.254 0.0621 1.207 1.61 0.976 2.64 PRS_PLINK_2.51188643150958e.06 FALSE 290 Delirium dementia and amnestic and other cognitive disorders Both 642 1464 5 mental disorders magenta 1464, 642 366, 184 366, 131 366, 159 366, 168 0.00989 0.0505 0.845 0.07332 1.01 0.915 1.11 -0.348 0.138 0.0116 1.934 0.706 0.539 0.925 -0.167 0.133 0.209 0.679 0.846 0.652 1.1 -0.0854 0.133 0.52 0.2843 0.918 0.708 1.19 PRS_PLINK_2.51188643150958e.06 FALSE 290.1 Dementias Both 307 647 5 mental disorders magenta 647, 307 162, 88 162, 64 161, 89 162, 66 -0.0397 0.0726 0.584 0.2332 0.961 0.834 1.11 -0.289 0.201 0.15 0.8237 0.749 0.506 1.11 0.00972 0.189 0.959 0.0182 1.01 0.697 1.46 -0.33 0.201 0.101 0.9948 0.719 0.485 1.07 PRS_PLINK_2.51188643150958e.06 FALSE 290.11 Alzheimer's disease Both 92 186 5 mental disorders magenta 186, 92 47, 25 46, 16 46, 27 47, 24 -0.136 0.151 0.368 0.4336 0.873 0.65 1.17 -0.427 0.395 0.28 0.5533 0.652 0.301 1.42 0.0213 0.369 0.954 0.02045 1.02 0.496 2.1 -0.063 0.371 0.865 0.06281 0.939 0.453 1.94 PRS_PLINK_2.51188643150958e.06 FALSE 290.12 Dementia with cerebral degenerations Both 63 100 5 mental disorders magenta 100, 63 25, 20 25, 6 25, 23 25, 14 -0.0745 0.186 0.688 0.1622 0.928 0.645 1.34 -1.14 0.561 0.0424 1.372 0.32 0.107 0.962 0.0201 0.446 0.964 0.01592 1.02 0.426 2.44 -0.338 0.476 0.478 0.321 0.713 0.28 1.81 PRS_PLINK_2.51188643150958e.06 FALSE 290.13 Senile dementia Both 194 412 5 mental disorders magenta 412, 194 103, 59 103, 41 103, 45 103, 49 -0.0143 0.0942 0.879 0.05594 0.986 0.82 1.19 -0.35 0.248 0.158 0.8008 0.705 0.433 1.15 -0.292 0.246 0.234 0.6299 0.747 0.461 1.21 -0.292 0.247 0.236 0.6264 0.747 0.46 1.21 PRS_PLINK_2.51188643150958e.06 FALSE 290.16 Vascular dementia Both 57 99 5 mental disorders magenta 99, 57 25, 17 25, 6 24, 18 25, 16 0.101 0.238 0.671 0.1732 1.11 0.694 1.76 -1.17 0.604 0.052 1.284 0.309 0.0947 1.01 0.138 0.475 0.772 0.1122 1.15 0.452 2.91 0.0132 0.473 0.978 0.009744 1.01 0.401 2.56 PRS_PLINK_2.51188643150958e.06 FALSE 290.2 Delirium due to conditions classified elsewhere Both 346 889 5 mental disorders magenta 889, 346 223, 96 222, 85 222, 71 222, 94 0.0105 0.0674 0.877 0.05709 1.01 0.885 1.15 -0.107 0.179 0.552 0.2583 0.899 0.633 1.28 -0.303 0.187 0.105 0.9777 0.739 0.512 1.07 0.0308 0.177 0.862 0.06454 1.03 0.729 1.46 PRS_PLINK_2.51188643150958e.06 FALSE 290.3 Other persistent mental disorders due to conditions classified elsewhere Both 486 1129 5 mental disorders magenta 1129, 486 283, 142 282, 116 282, 110 282, 118 -0.0335 0.0571 0.558 0.2535 0.967 0.865 1.08 -0.201 0.153 0.188 0.7256 0.818 0.606 1.1 -0.258 0.155 0.0947 1.023 0.772 0.57 1.05 -0.212 0.154 0.166 0.7786 0.809 0.599 1.09 PRS_PLINK_2.51188643150958e.06 FALSE 291 Other specified nonpsychotic and/or transient mental disorders Both 1075 3117 5 mental disorders magenta 3117, 1075 780, 276 779, 279 779, 277 779, 243 -0.0235 0.0361 0.516 0.2875 0.977 0.91 1.05 0.0138 0.0998 0.89 0.05052 1.01 0.834 1.23 -0.00379 0.1 0.97 0.01331 0.996 0.819 1.21 -0.136 0.103 0.185 0.7332 0.872 0.713 1.07 PRS_PLINK_2.51188643150958e.06 FALSE 291.1 Transient mental disorders due to conditions classified elsewhere Both 54 232 5 mental disorders magenta 232, 54 58, 12 58, 19 58, 10 58, 13 0.117 0.149 0.43 0.3669 1.12 0.84 1.5 0.501 0.433 0.248 0.6063 1.65 0.706 3.86 -0.159 0.471 0.736 0.1333 0.853 0.339 2.15 0.34 0.46 0.46 0.3372 1.4 0.57 3.46 PRS_PLINK_2.51188643150958e.06 FALSE 291.4 Specific nonpsychotic mental disorders due to brain damage Both 221 613 5 mental disorders magenta 613, 221 154, 71 153, 49 153, 51 153, 50 -0.149 0.0855 0.0812 1.091 0.861 0.729 1.02 -0.349 0.228 0.125 0.9027 0.705 0.451 1.1 -0.321 0.222 0.148 0.8289 0.725 0.469 1.12 -0.322 0.227 0.156 0.8059 0.725 0.464 1.13 PRS_PLINK_2.51188643150958e.06 FALSE 291.8 Alteration of consciousness Both 883 2514 5 mental disorders magenta 2514, 883 629, 222 628, 243 628, 229 629, 189 -0.028 0.0399 0.484 0.3154 0.972 0.899 1.05 0.112 0.11 0.31 0.5089 1.12 0.902 1.39 0.0164 0.111 0.882 0.05448 1.02 0.818 1.26 -0.159 0.116 0.17 0.7691 0.853 0.68 1.07 PRS_PLINK_2.51188643150958e.06 FALSE 292 Neurological disorders Both 2328 4578 5 mental disorders magenta 4578, 2328 1145, 590 1144, 559 1144, 598 1145, 580 0.00274 0.0261 0.916 0.03793 1 0.953 1.06 -0.0773 0.0745 0.299 0.5244 0.926 0.8 1.07 0.0187 0.0735 0.799 0.0973 1.02 0.882 1.18 -0.0189 0.0742 0.799 0.09763 0.981 0.849 1.13 PRS_PLINK_2.51188643150958e.06 FALSE 292.1 Aphasia/speech disturbance Both 665 2357 5 mental disorders magenta 2357, 665 590, 172 589, 159 589, 169 589, 165 0.00685 0.045 0.879 0.05593 1.01 0.922 1.1 -0.0683 0.125 0.586 0.232 0.934 0.731 1.19 -0.00484 0.124 0.969 0.01377 0.995 0.781 1.27 -0.0127 0.126 0.92 0.03635 0.987 0.772 1.26 PRS_PLINK_2.51188643150958e.06 FALSE 292.11 Aphasia Both 235 795 5 mental disorders magenta 795, 235 199, 70 199, 42 198, 75 199, 48 -0.0331 0.0734 0.652 0.1855 0.967 0.838 1.12 -0.476 0.22 0.0306 1.514 0.622 0.404 0.957 0.147 0.198 0.457 0.3402 1.16 0.786 1.71 -0.322 0.217 0.138 0.8606 0.725 0.474 1.11 PRS_PLINK_2.51188643150958e.06 FALSE 292.12 Symbolic dysfunction Both 78 209 5 mental disorders magenta 209, 78 53, 26 52, 14 52, 18 52, 20 -0.0114 0.148 0.939 0.02749 0.989 0.74 1.32 -0.572 0.397 0.15 0.8252 0.564 0.259 1.23 -0.381 0.383 0.319 0.4957 0.683 0.322 1.45 -0.0554 0.4 0.89 0.05067 0.946 0.432 2.07 PRS_PLINK_2.51188643150958e.06 FALSE 292.2 Mild cognitive impairment Both 246 471 5 mental disorders magenta 471, 246 118, 76 118, 69 117, 47 118, 54 -0.127 0.0837 0.129 0.8895 0.881 0.747 1.04 -0.0643 0.216 0.766 0.1158 0.938 0.614 1.43 -0.433 0.233 0.0629 1.201 0.648 0.411 1.02 -0.342 0.226 0.131 0.8826 0.711 0.456 1.11 PRS_PLINK_2.51188643150958e.06 FALSE 292.3 Memory loss Both 1059 2342 5 mental disorders magenta 2342, 1059 586, 276 585, 250 585, 288 586, 245 -0.00894 0.0369 0.809 0.0923 0.991 0.922 1.07 -0.0918 0.106 0.387 0.4123 0.912 0.741 1.12 0.0544 0.104 0.6 0.2222 1.06 0.862 1.29 -0.113 0.107 0.294 0.5312 0.894 0.724 1.1 PRS_PLINK_2.51188643150958e.06 FALSE 292.4 Altered mental status Both 1119 2836 5 mental disorders magenta 2836, 1119 709, 298 709, 255 709, 281 709, 284 0.00925 0.0364 0.799 0.09729 1.01 0.94 1.08 -0.122 0.102 0.232 0.6349 0.885 0.725 1.08 -0.0647 0.0999 0.517 0.2862 0.937 0.771 1.14 -0.0315 0.1 0.752 0.1236 0.969 0.797 1.18 PRS_PLINK_2.51188643150958e.06 FALSE 292.5 Transient alteration of awareness Both 199 577 5 mental disorders magenta 577, 199 145, 61 144, 39 144, 50 144, 49 -0.00994 0.0824 0.904 0.0438 0.99 0.842 1.16 -0.429 0.239 0.0722 1.142 0.651 0.408 1.04 -0.224 0.231 0.333 0.4782 0.799 0.508 1.26 -0.155 0.234 0.508 0.2944 0.856 0.541 1.35 PRS_PLINK_2.51188643150958e.06 FALSE 292.6 Hallucinations Both 133 269 5 mental disorders magenta 269, 133 68, 38 67, 27 67, 31 67, 37 0.0648 0.112 0.562 0.25 1.07 0.857 1.33 -0.292 0.309 0.343 0.4642 0.747 0.408 1.37 -0.184 0.308 0.55 0.2594 0.832 0.455 1.52 -0.00334 0.299 0.991 0.003896 0.997 0.555 1.79 PRS_PLINK_2.51188643150958e.06 FALSE 293 Symptoms involving head and neck Both 136 667 5 mental disorders magenta 667, 136 167, 42 167, 25 166, 30 167, 39 0.0137 0.0925 0.882 0.05452 1.01 0.846 1.22 -0.494 0.275 0.0727 1.139 0.61 0.356 1.05 -0.284 0.263 0.28 0.5526 0.753 0.449 1.26 -0.0272 0.251 0.914 0.03918 0.973 0.595 1.59 PRS_PLINK_2.51188643150958e.06 FALSE 293.1 Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS] Both 1080 5905 5 mental disorders magenta 5905, 1080 1476, 278 1476, 290 1476, 267 1476, 245 -0.0158 0.0332 0.633 0.1983 0.984 0.922 1.05 0.0231 0.092 0.801 0.09613 1.02 0.855 1.23 -0.0428 0.0937 0.648 0.1885 0.958 0.797 1.15 -0.121 0.0957 0.206 0.6855 0.886 0.735 1.07 PRS_PLINK_2.51188643150958e.06 FALSE 295 Schizophrenia and other psychotic disorders Both 444 663 5 mental disorders magenta 663, 444 166, 105 166, 125 165, 112 166, 102 0.00333 0.0635 0.958 0.01859 1 0.886 1.14 0.18 0.174 0.301 0.5211 1.2 0.851 1.69 0.0677 0.177 0.702 0.1536 1.07 0.756 1.51 -0.0441 0.18 0.806 0.09364 0.957 0.673 1.36 PRS_PLINK_2.51188643150958e.06 FALSE 295.1 Schizophrenia Both 40 89 5 mental disorders magenta 89, 40 23, 9 22, 13 22, 10 22, 8 0.0179 0.176 0.919 0.03675 1.02 0.721 1.44 0.48 0.574 0.402 0.3954 1.62 0.525 4.97 0.317 0.61 0.603 0.2196 1.37 0.415 4.54 -0.151 0.664 0.82 0.08602 0.86 0.234 3.16 PRS_PLINK_2.51188643150958e.06 TRUE 295.2 Paranoid disorders Both 49 81 5 mental disorders magenta 81, 49 21, 8 20, 18 20, 14 20, 9 0.0571 0.229 0.803 0.09542 1.06 0.676 1.66 0.797 0.551 0.148 0.8301 2.22 0.754 6.53 0.473 0.569 0.406 0.3913 1.6 0.526 4.9 0.315 0.66 0.634 0.1982 1.37 0.376 4.99 PRS_PLINK_2.51188643150958e.06 TRUE 295.3 Psychosis Both 396 554 5 mental disorders magenta 554, 396 139, 99 138, 104 138, 102 139, 91 -0.0649 0.0711 0.361 0.4425 0.937 0.815 1.08 0.0637 0.188 0.735 0.1336 1.07 0.737 1.54 -0.00135 0.188 0.994 0.002489 0.999 0.69 1.44 -0.0959 0.192 0.618 0.2087 0.909 0.623 1.32 PRS_PLINK_2.51188643150958e.06 FALSE 296 Mood disorders Both 4093 1443 5 mental disorders magenta 1443, 4093 361, 974 361, 1061 360, 1027 361, 1031 0.0503 0.0305 0.0997 1.001 1.05 0.99 1.12 0.114 0.0882 0.197 0.7047 1.12 0.943 1.33 0.0869 0.0887 0.327 0.4852 1.09 0.917 1.3 0.0666 0.0889 0.454 0.3432 1.07 0.898 1.27 PRS_PLINK_2.51188643150958e.06 FALSE 296.1 Bipolar Both 415 760 5 mental disorders magenta 760, 415 190, 107 190, 91 190, 120 190, 97 -0.0175 0.0582 0.764 0.1171 0.983 0.877 1.1 -0.148 0.178 0.408 0.3893 0.863 0.608 1.22 0.128 0.17 0.452 0.3453 1.14 0.814 1.59 -0.0985 0.177 0.577 0.2385 0.906 0.641 1.28 PRS_PLINK_2.51188643150958e.06 FALSE 296.2 Depression Both 4002 1444 5 mental disorders magenta 1444, 4002 361, 956 361, 1034 361, 1004 361, 1008 0.0509 0.0306 0.0968 1.014 1.05 0.991 1.12 0.106 0.0884 0.232 0.6352 1.11 0.935 1.32 0.0784 0.089 0.378 0.422 1.08 0.908 1.29 0.0633 0.0892 0.478 0.3208 1.07 0.894 1.27 PRS_PLINK_2.51188643150958e.06 FALSE 296.22 Major depressive disorder Both 3750 1443 5 mental disorders magenta 1443, 3750 361, 887 361, 970 360, 950 361, 943 0.0538 0.0311 0.0842 1.075 1.06 0.993 1.12 0.117 0.0894 0.192 0.7171 1.12 0.943 1.34 0.102 0.09 0.258 0.5888 1.11 0.928 1.32 0.0722 0.0902 0.424 0.3726 1.07 0.901 1.28 PRS_PLINK_2.51188643150958e.06 FALSE 297 Suicidal ideation or attempt Both 366 597 5 mental disorders magenta 597, 366 150, 91 149, 93 149, 96 149, 86 0.00251 0.0646 0.969 0.01366 1 0.883 1.14 0.0524 0.196 0.789 0.1027 1.05 0.717 1.55 0.0744 0.192 0.698 0.1559 1.08 0.739 1.57 -0.055 0.194 0.777 0.1093 0.947 0.647 1.39 PRS_PLINK_2.51188643150958e.06 FALSE 297.1 Suicidal ideation Both 297 491 5 mental disorders magenta 491, 297 123, 76 123, 74 122, 77 123, 70 0.0156 0.0715 0.827 0.08238 1.02 0.883 1.17 -0.0273 0.22 0.901 0.04505 0.973 0.632 1.5 -0.00782 0.214 0.971 0.01286 0.992 0.653 1.51 -0.0965 0.216 0.655 0.1835 0.908 0.594 1.39 PRS_PLINK_2.51188643150958e.06 FALSE 297.2 Suicide or self-inflicted injury Both 117 167 5 mental disorders magenta 167, 117 42, 32 42, 24 41, 37 42, 24 -0.0353 0.125 0.777 0.1097 0.965 0.756 1.23 -0.228 0.371 0.539 0.2682 0.796 0.384 1.65 0.224 0.339 0.51 0.2928 1.25 0.643 2.43 -0.275 0.371 0.46 0.3374 0.76 0.367 1.57 PRS_PLINK_2.51188643150958e.06 FALSE 300 Anxiety disorders Both 4009 1443 5 mental disorders magenta 1443, 4009 361, 940 361, 1037 360, 1015 361, 1016 0.0614 0.0307 0.0458 1.34 1.06 1 1.13 0.117 0.0888 0.186 0.7313 1.12 0.945 1.34 0.0971 0.089 0.275 0.5599 1.1 0.926 1.31 0.0857 0.0893 0.337 0.4721 1.09 0.915 1.3 PRS_PLINK_2.51188643150958e.06 FALSE 300.1 Anxiety disorder Both 3790 1442 5 mental disorders magenta 1442, 3790 361, 885 360, 980 360, 959 361, 965 0.0675 0.0311 0.0299 1.525 1.07 1.01 1.14 0.126 0.0897 0.159 0.7973 1.13 0.952 1.35 0.0982 0.0899 0.275 0.5612 1.1 0.925 1.32 0.0889 0.0902 0.324 0.4896 1.09 0.916 1.3 PRS_PLINK_2.51188643150958e.06 FALSE 300.11 Generalized anxiety disorder Both 1877 1428 5 mental disorders magenta 1428, 1877 357, 437 357, 474 357, 489 357, 476 0.0796 0.0359 0.0267 1.573 1.08 1.01 1.16 0.0854 0.104 0.412 0.3847 1.09 0.888 1.34 0.155 0.104 0.139 0.857 1.17 0.951 1.43 0.127 0.105 0.226 0.6467 1.14 0.925 1.39 PRS_PLINK_2.51188643150958e.06 FALSE 300.12 Agorophobia, social phobia, and panic disorder Both 469 800 5 mental disorders magenta 800, 469 200, 102 200, 125 200, 120 200, 122 0.0964 0.0597 0.106 0.9746 1.1 0.98 1.24 0.269 0.174 0.122 0.9122 1.31 0.93 1.84 0.244 0.173 0.159 0.7983 1.28 0.909 1.79 0.196 0.174 0.26 0.5845 1.22 0.865 1.71 PRS_PLINK_2.51188643150958e.06 FALSE 300.13 Phobia Both 358 683 5 mental disorders magenta 683, 358 171, 90 171, 108 170, 69 171, 91 0.0265 0.063 0.674 0.1716 1.03 0.908 1.16 0.224 0.185 0.226 0.6451 1.25 0.87 1.8 -0.229 0.198 0.247 0.6071 0.796 0.54 1.17 0.00853 0.19 0.964 0.01586 1.01 0.695 1.46 PRS_PLINK_2.51188643150958e.06 FALSE 300.3 Obsessive-compulsive disorders Both 117 207 5 mental disorders magenta 207, 117 52, 26 52, 30 51, 33 52, 28 0.0264 0.112 0.814 0.08935 1.03 0.824 1.28 0.2 0.363 0.582 0.2354 1.22 0.599 2.49 0.404 0.345 0.243 0.6151 1.5 0.761 2.95 0.0905 0.359 0.801 0.09621 1.09 0.541 2.21 PRS_PLINK_2.51188643150958e.06 FALSE 300.4 Dysthymic disorder Both 951 1186 5 mental disorders magenta 1186, 951 297, 233 296, 239 296, 231 297, 248 0.02 0.0422 0.635 0.197 1.02 0.939 1.11 0.0672 0.127 0.597 0.2241 1.07 0.834 1.37 0.0727 0.127 0.567 0.2467 1.08 0.839 1.38 0.0889 0.126 0.479 0.3196 1.09 0.854 1.4 PRS_PLINK_2.51188643150958e.06 FALSE 300.8 Acute reaction to stress Both 205 349 5 mental disorders magenta 349, 205 88, 63 87, 37 87, 54 87, 51 -0.00385 0.09 0.966 0.01506 0.996 0.835 1.19 -0.482 0.269 0.0739 1.131 0.618 0.364 1.05 -0.135 0.245 0.581 0.2359 0.873 0.54 1.41 -0.252 0.25 0.312 0.5058 0.777 0.476 1.27 PRS_PLINK_2.51188643150958e.06 FALSE 300.9 Posttraumatic stress disorder Both 299 506 5 mental disorders magenta 506, 299 127, 62 126, 71 126, 87 127, 79 0.15 0.0755 0.0465 1.333 1.16 1 1.35 0.122 0.229 0.593 0.227 1.13 0.721 1.77 0.374 0.213 0.0792 1.101 1.45 0.957 2.21 0.303 0.218 0.163 0.7866 1.35 0.884 2.07 PRS_PLINK_2.51188643150958e.06 FALSE 301 Personality disorders Both 199 328 5 mental disorders magenta 328, 199 82, 48 82, 47 82, 50 82, 54 0.104 0.0895 0.245 0.6116 1.11 0.931 1.32 0.154 0.274 0.575 0.2404 1.17 0.681 2 0.0232 0.263 0.93 0.0317 1.02 0.612 1.71 0.178 0.26 0.492 0.3077 1.2 0.719 1.99 PRS_PLINK_2.51188643150958e.06 FALSE 301.2 Antisocial/borderline personality disorder Both 111 176 5 mental disorders magenta 176, 111 44, 21 44, 24 44, 35 44, 31 0.197 0.141 0.161 0.793 1.22 0.924 1.61 0.176 0.408 0.667 0.176 1.19 0.535 2.65 0.519 0.37 0.161 0.7942 1.68 0.814 3.47 0.522 0.383 0.173 0.761 1.68 0.795 3.57 PRS_PLINK_2.51188643150958e.06 FALSE 302 Sexual and gender identity disorders Both 902 980 5 mental disorders magenta 980, 902 245, 210 245, 247 245, 217 245, 228 0.0621 0.0462 0.179 0.7459 1.06 0.972 1.16 0.172 0.135 0.203 0.6935 1.19 0.912 1.55 0.0417 0.136 0.76 0.1193 1.04 0.798 1.36 0.0898 0.135 0.507 0.2949 1.09 0.839 1.43 PRS_PLINK_2.51188643150958e.06 FALSE 302.1 Decreased libido Both 163 343 5 mental disorders magenta 343, 163 86, 34 86, 49 85, 32 86, 48 0.152 0.101 0.134 0.8735 1.16 0.954 1.42 0.469 0.286 0.101 0.9965 1.6 0.913 2.8 -0.0767 0.306 0.802 0.09578 0.926 0.508 1.69 0.406 0.281 0.149 0.8277 1.5 0.865 2.6 PRS_PLINK_2.51188643150958e.06 FALSE 303 Psychogenic and somatoform disorders Both 2191 1419 5 mental disorders magenta 1419, 2191 355, 516 355, 559 354, 540 355, 575 0.053 0.0336 0.115 0.9411 1.05 0.987 1.13 0.0843 0.099 0.395 0.4038 1.09 0.896 1.32 0.0458 0.099 0.643 0.1916 1.05 0.862 1.27 0.123 0.0982 0.209 0.6809 1.13 0.933 1.37 PRS_PLINK_2.51188643150958e.06 FALSE 303.1 Dissociative disorder Both 81 131 5 mental disorders magenta 131, 81 33, 18 33, 22 32, 23 33, 18 0.0574 0.132 0.664 0.1779 1.06 0.817 1.37 0.159 0.444 0.721 0.1421 1.17 0.491 2.8 0.348 0.434 0.423 0.374 1.42 0.605 3.32 0.0473 0.44 0.914 0.03892 1.05 0.443 2.48 PRS_PLINK_2.51188643150958e.06 FALSE 303.3 Psychogenic disorder Both 2069 1414 5 mental disorders magenta 1414, 2069 354, 489 353, 523 353, 510 354, 546 0.0589 0.0342 0.085 1.07 1.06 0.992 1.13 0.0838 0.101 0.405 0.3921 1.09 0.893 1.32 0.0405 0.101 0.687 0.1629 1.04 0.855 1.27 0.137 0.0995 0.17 0.7696 1.15 0.943 1.39 PRS_PLINK_2.51188643150958e.06 FALSE 303.31 Gastrointestinal malfunction arising from mental factors Both 164 363 5 mental disorders magenta 363, 164 91, 35 91, 41 90, 40 91, 48 0.0143 0.0973 0.883 0.05401 1.01 0.838 1.23 0.0937 0.281 0.739 0.1314 1.1 0.633 1.91 0.136 0.281 0.628 0.2018 1.15 0.661 1.99 0.33 0.278 0.236 0.6279 1.39 0.807 2.4 PRS_PLINK_2.51188643150958e.06 FALSE 303.4 Somatoform disorder Both 397 761 5 mental disorders magenta 761, 397 191, 89 190, 100 190, 98 190, 109 0.0375 0.0591 0.526 0.2794 1.04 0.925 1.17 0.145 0.181 0.422 0.3743 1.16 0.811 1.65 0.144 0.183 0.429 0.3672 1.16 0.807 1.65 0.232 0.179 0.194 0.7132 1.26 0.889 1.79 PRS_PLINK_2.51188643150958e.06 FALSE 304 Adjustment reaction Both 1374 1432 5 mental disorders magenta 1432, 1374 358, 313 358, 343 358, 341 358, 377 0.102 0.0395 0.00974 2.011 1.11 1.03 1.2 0.0991 0.111 0.373 0.4282 1.1 0.888 1.37 0.11 0.111 0.323 0.4902 1.12 0.897 1.39 0.199 0.11 0.0714 1.147 1.22 0.983 1.51 PRS_PLINK_2.51188643150958e.06 FALSE 305.2 Eating disorder Both 498 600 5 mental disorders magenta 600, 498 150, 122 150, 110 150, 130 150, 136 0.0673 0.0611 0.271 0.5669 1.07 0.949 1.21 -0.032 0.181 0.859 0.06578 0.968 0.679 1.38 0.116 0.176 0.51 0.2923 1.12 0.796 1.58 0.137 0.174 0.434 0.3628 1.15 0.814 1.61 PRS_PLINK_2.51188643150958e.06 FALSE 306 Other mental disorder Both 655 962 5 mental disorders magenta 962, 655 241, 166 240, 167 240, 168 241, 154 0.0127 0.0507 0.802 0.09595 1.01 0.917 1.12 0.061 0.147 0.677 0.1694 1.06 0.798 1.42 0.0855 0.147 0.56 0.2521 1.09 0.817 1.45 -0.0422 0.147 0.775 0.1109 0.959 0.718 1.28 PRS_PLINK_2.51188643150958e.06 FALSE 306.1 Mental disorders durring/after pregnancy Female 155 239 5 mental disorders magenta 239, 155 60, 28 60, 39 59, 44 60, 44 0.184 0.107 0.0842 1.075 1.2 0.975 1.48 0.305 0.324 0.348 0.4586 1.36 0.718 2.56 0.521 0.321 0.105 0.979 1.68 0.897 3.16 0.405 0.317 0.201 0.6975 1.5 0.806 2.79 PRS_PLINK_2.51188643150958e.06 FALSE 306.9 Tension headache Both 301 499 5 mental disorders magenta 499, 301 125, 79 125, 68 124, 92 125, 62 -0.0316 0.0694 0.649 0.1879 0.969 0.846 1.11 -0.0705 0.216 0.744 0.1282 0.932 0.61 1.42 0.157 0.204 0.444 0.353 1.17 0.783 1.75 -0.181 0.217 0.405 0.3927 0.834 0.545 1.28 PRS_PLINK_2.51188643150958e.06 FALSE 312 Conduct disorders Both 108 342 5 mental disorders magenta 342, 108 86, 35 85, 24 85, 25 86, 24 -0.0902 0.12 0.453 0.3436 0.914 0.722 1.16 -0.409 0.31 0.188 0.727 0.664 0.362 1.22 -0.352 0.316 0.265 0.5771 0.703 0.379 1.31 -0.404 0.315 0.2 0.6979 0.668 0.36 1.24 PRS_PLINK_2.51188643150958e.06 FALSE 312.3 Impulse control disorder Both 30 108 5 mental disorders magenta 108, 30 27, 8 27, 9 27, 7 27, 6 -0.123 0.207 0.551 0.2588 0.884 0.589 1.33 0.036 0.587 0.951 0.02174 1.04 0.328 3.28 0.0762 0.683 0.911 0.0404 1.08 0.283 4.11 -0.311 0.637 0.626 0.2037 0.733 0.21 2.55 PRS_PLINK_2.51188643150958e.06 TRUE 313 Pervasive developmental disorders Both 386 1939 5 mental disorders magenta 1939, 386 485, 97 485, 103 484, 91 485, 95 0.00956 0.0557 0.864 0.06362 1.01 0.905 1.13 0.0529 0.155 0.733 0.1346 1.05 0.778 1.43 -0.0625 0.16 0.696 0.1575 0.939 0.687 1.29 -0.0213 0.159 0.893 0.04897 0.979 0.717 1.34 PRS_PLINK_2.51188643150958e.06 FALSE 313.1 Attention deficit hyperactivity disorder Both 323 1739 5 mental disorders magenta 1739, 323 435, 79 435, 88 434, 79 435, 77 0.0145 0.0603 0.81 0.09142 1.01 0.901 1.14 0.11 0.169 0.515 0.2879 1.12 0.802 1.55 0.0065 0.173 0.97 0.01322 1.01 0.717 1.41 -0.0183 0.174 0.916 0.03813 0.982 0.698 1.38 PRS_PLINK_2.51188643150958e.06 FALSE 313.2 Tics and stuttering Both 26 97 5 mental disorders magenta 97, 26 25, 9 24, 9 24, 3 24, 5 -0.138 0.201 0.493 0.3069 0.871 0.588 1.29 0.527 0.629 0.403 0.3949 1.69 0.493 5.81 -0.817 0.734 0.265 0.576 0.442 0.105 1.86 -0.347 0.65 0.593 0.2266 0.707 0.198 2.53 PRS_PLINK_2.51188643150958e.06 TRUE 313.3 Autism Both 17 55 5 mental disorders magenta 55, 17 14, 4 14, 3 13, 4 14, 6 -0.0707 0.302 0.815 0.08881 0.932 0.515 1.68 -0.279 0.941 0.767 0.1154 0.756 0.12 4.78 0.597 0.902 0.508 0.2944 1.82 0.31 10.6 -0.135 0.971 0.889 0.05094 0.874 0.13 5.86 PRS_PLINK_2.51188643150958e.06 TRUE 315 Develomental delays and disorders Both 272 1006 5 mental disorders magenta 1006, 272 252, 64 251, 74 251, 64 252, 70 0.0755 0.0697 0.279 0.5541 1.08 0.941 1.24 0.176 0.195 0.366 0.4369 1.19 0.814 1.75 0.0332 0.199 0.867 0.0619 1.03 0.7 1.53 0.0717 0.196 0.714 0.1463 1.07 0.732 1.58 PRS_PLINK_2.51188643150958e.06 FALSE 315.1 Learning disorder Both 23 98 5 mental disorders magenta 98, 23 25, 4 24, 6 24, 8 25, 5 0.132 0.21 0.531 0.2749 1.14 0.756 1.72 0.588 0.734 0.423 0.3736 1.8 0.427 7.59 0.761 0.687 0.268 0.5714 2.14 0.557 8.23 0.304 0.709 0.668 0.175 1.35 0.338 5.43 PRS_PLINK_2.51188643150958e.06 TRUE 315.2 Speech and language disorder Both 102 372 5 mental disorders magenta 372, 102 93, 14 93, 33 93, 27 93, 28 0.275 0.116 0.0175 1.757 1.32 1.05 1.65 0.866 0.354 0.0146 1.836 2.38 1.19 4.76 0.817 0.372 0.0282 1.55 2.26 1.09 4.7 0.656 0.367 0.0744 1.129 1.93 0.938 3.96 PRS_PLINK_2.51188643150958e.06 FALSE 316 Substance addiction and disorders Both 1173 4288 5 mental disorders magenta 4288, 1173 1071, 278 1072, 288 1072, 329 1072, 278 0.0408 0.0337 0.226 0.6454 1.04 0.975 1.11 0.0537 0.0953 0.573 0.2417 1.06 0.875 1.27 0.168 0.0928 0.0697 1.157 1.18 0.987 1.42 -0.0145 0.0958 0.88 0.0555 0.986 0.817 1.19 PRS_PLINK_2.51188643150958e.06 FALSE 316.1 Polyneuropathy due to drugs Both 187 914 5 mental disorders magenta 914, 187 229, 37 228, 55 228, 51 229, 44 0.0562 0.0883 0.525 0.28 1.06 0.89 1.26 0.407 0.234 0.0824 1.084 1.5 0.949 2.38 0.329 0.237 0.165 0.782 1.39 0.873 2.21 0.201 0.244 0.411 0.3862 1.22 0.758 1.97 PRS_PLINK_2.51188643150958e.06 FALSE 317 Alcohol-related disorders Both 734 2823 5 mental disorders magenta 2823, 734 705, 199 706, 180 705, 186 706, 169 -0.0306 0.0408 0.453 0.3441 0.97 0.895 1.05 -0.0911 0.116 0.434 0.3626 0.913 0.727 1.15 -0.0537 0.115 0.642 0.1926 0.948 0.756 1.19 -0.17 0.118 0.151 0.8219 0.844 0.67 1.06 PRS_PLINK_2.51188643150958e.06 FALSE 317.1 Alcoholism Both 592 2371 5 mental disorders magenta 2371, 592 592, 161 593, 138 592, 153 593, 140 -0.00184 0.0452 0.968 0.01433 0.998 0.914 1.09 -0.135 0.13 0.302 0.5205 0.874 0.677 1.13 -0.0345 0.128 0.787 0.104 0.966 0.752 1.24 -0.15 0.13 0.25 0.6016 0.861 0.667 1.11 PRS_PLINK_2.51188643150958e.06 FALSE 317.11 Alcoholic liver damage Both 156 522 5 mental disorders magenta 522, 156 131, 43 130, 39 130, 34 131, 40 -0.067 0.0865 0.439 0.3574 0.935 0.789 1.11 -0.0859 0.258 0.739 0.1314 0.918 0.554 1.52 -0.255 0.264 0.335 0.4752 0.775 0.461 1.3 -0.112 0.259 0.667 0.1758 0.894 0.538 1.49 PRS_PLINK_2.51188643150958e.06 FALSE 318 Tobacco use disorder Both 1964 4619 5 mental disorders magenta 4619, 1964 1154, 490 1155, 490 1154, 512 1155, 472 -0.00435 0.027 0.872 0.05947 0.996 0.944 1.05 0.00525 0.0772 0.946 0.02421 1.01 0.864 1.17 0.0384 0.0766 0.616 0.2102 1.04 0.894 1.21 -0.0613 0.0778 0.431 0.3658 0.941 0.808 1.1 PRS_PLINK_2.51188643150958e.06 FALSE 320 Meningitis Both 130 551 6 neurological darkblue 551, 130 138, 37 138, 33 137, 27 138, 33 -0.0419 0.0979 0.668 0.1749 0.959 0.792 1.16 -0.0909 0.267 0.734 0.1345 0.913 0.541 1.54 -0.307 0.284 0.28 0.5533 0.736 0.422 1.28 -0.0629 0.27 0.816 0.08834 0.939 0.553 1.59 PRS_PLINK_2.51188643150958e.06 FALSE 323 Encephalitis Both 87 294 6 neurological darkblue 294, 87 74, 29 73, 11 73, 16 74, 31 0.0518 0.123 0.674 0.1714 1.05 0.827 1.34 -1.03 0.401 0.0101 1.997 0.356 0.163 0.782 -0.617 0.356 0.0833 1.079 0.54 0.268 1.08 0.0178 0.32 0.956 0.0197 1.02 0.544 1.9 PRS_PLINK_2.51188643150958e.06 FALSE 323.8 Encephalitis, non-infectious Both 76 229 6 neurological darkblue 229, 76 58, 27 57, 10 57, 13 57, 26 0.00362 0.129 0.978 0.009862 1 0.78 1.29 -0.991 0.429 0.0209 1.68 0.371 0.16 0.861 -0.828 0.399 0.0378 1.423 0.437 0.2 0.954 -0.0222 0.345 0.949 0.02288 0.978 0.498 1.92 PRS_PLINK_2.51188643150958e.06 FALSE 324 Other CNS infection and poliomyelitis Both 85 472 6 neurological darkblue 472, 85 118, 26 118, 19 118, 22 118, 18 -0.0964 0.11 0.381 0.4196 0.908 0.732 1.13 -0.33 0.326 0.311 0.5067 0.719 0.38 1.36 -0.215 0.319 0.5 0.3008 0.807 0.432 1.51 -0.383 0.332 0.249 0.604 0.682 0.356 1.31 PRS_PLINK_2.51188643150958e.06 FALSE 325 Phlebitis and thrombophlebitis of intracranial venous sinuses Both 21 79 6 neurological darkblue 79, 21 20, 6 20, 4 19, 5 20, 6 0.0239 0.211 0.91 0.04111 1.02 0.678 1.55 0.494 0.935 0.597 0.224 1.64 0.262 10.2 0.144 0.75 0.848 0.07175 1.16 0.265 5.03 0.434 0.871 0.618 0.2089 1.54 0.28 8.51 PRS_PLINK_2.51188643150958e.06 TRUE 327 Sleep disorders Both 4398 3009 6 neurological darkblue 3009, 4398 753, 1126 752, 1071 752, 1120 752, 1080 -0.0271 0.0239 0.258 0.5878 0.973 0.929 1.02 -0.051 0.0674 0.45 0.3471 0.95 0.833 1.08 -0.00543 0.0673 0.936 0.02888 0.995 0.872 1.13 -0.0479 0.0675 0.478 0.3208 0.953 0.835 1.09 PRS_PLINK_2.51188643150958e.06 FALSE 327.1 Hypersomnia Both 899 1932 6 neurological darkblue 1932, 899 483, 227 483, 207 483, 248 483, 217 0.0188 0.0419 0.653 0.185 1.02 0.939 1.11 -0.091 0.116 0.434 0.3624 0.913 0.727 1.15 0.0878 0.113 0.438 0.3582 1.09 0.874 1.36 -0.0404 0.115 0.726 0.139 0.96 0.766 1.2 PRS_PLINK_2.51188643150958e.06 FALSE 327.3 Sleep apnea Both 3130 2998 6 neurological darkblue 2998, 3130 750, 795 749, 748 749, 810 750, 776 -0.0263 0.0258 0.308 0.5119 0.974 0.926 1.02 -0.0666 0.0735 0.365 0.4379 0.936 0.81 1.08 0.0183 0.0729 0.802 0.096 1.02 0.883 1.17 -0.0399 0.0732 0.586 0.2324 0.961 0.833 1.11 PRS_PLINK_2.51188643150958e.06 FALSE 327.31 Central/nonobstroctive sleep apnea Both 220 525 6 neurological darkblue 525, 220 132, 65 131, 54 131, 57 131, 44 -0.186 0.089 0.0361 1.442 0.83 0.697 0.988 -0.213 0.226 0.345 0.4617 0.808 0.519 1.26 -0.161 0.228 0.48 0.3185 0.852 0.545 1.33 -0.436 0.238 0.0672 1.172 0.647 0.405 1.03 PRS_PLINK_2.51188643150958e.06 FALSE 327.32 Obstructive sleep apnea Both 2803 2950 6 neurological darkblue 2950, 2803 738, 708 737, 669 737, 719 738, 706 -0.0256 0.0265 0.335 0.4755 0.975 0.925 1.03 -0.0517 0.0758 0.495 0.305 0.95 0.818 1.1 0.02 0.0753 0.791 0.1018 1.02 0.88 1.18 -0.0178 0.0754 0.813 0.08975 0.982 0.847 1.14 PRS_PLINK_2.51188643150958e.06 FALSE 327.4 Insomnia Both 2181 2983 6 neurological darkblue 2983, 2181 746, 555 746, 526 745, 584 746, 515 -0.0347 0.0284 0.221 0.6548 0.966 0.914 1.02 -0.0531 0.0806 0.51 0.2923 0.948 0.81 1.11 0.0538 0.0795 0.499 0.3023 1.06 0.903 1.23 -0.0829 0.0811 0.307 0.513 0.92 0.785 1.08 PRS_PLINK_2.51188643150958e.06 FALSE 327.41 Organic or persistent insomnia Both 545 1305 6 neurological darkblue 1305, 545 327, 147 326, 122 326, 151 326, 125 -0.0806 0.0504 0.11 0.9589 0.923 0.836 1.02 -0.184 0.146 0.208 0.681 0.832 0.625 1.11 0.0231 0.142 0.87 0.06029 1.02 0.775 1.35 -0.177 0.147 0.229 0.6393 0.838 0.628 1.12 PRS_PLINK_2.51188643150958e.06 FALSE 327.5 Parasomnia Both 320 611 6 neurological darkblue 611, 320 153, 81 153, 85 152, 89 153, 65 -0.0244 0.0721 0.735 0.1338 0.976 0.847 1.12 0.0471 0.195 0.809 0.09186 1.05 0.715 1.54 0.0968 0.195 0.62 0.2078 1.1 0.752 1.61 -0.237 0.206 0.249 0.603 0.789 0.527 1.18 PRS_PLINK_2.51188643150958e.06 FALSE 327.6 Circadian rhythm sleep disorder Both 109 284 6 neurological darkblue 284, 109 71, 29 71, 25 71, 28 71, 27 -0.145 0.109 0.183 0.7384 0.865 0.699 1.07 -0.111 0.332 0.739 0.1311 0.895 0.467 1.72 -0.0486 0.33 0.883 0.05401 0.953 0.499 1.82 -0.0644 0.332 0.846 0.0725 0.938 0.489 1.8 PRS_PLINK_2.51188643150958e.06 FALSE 327.7 Sleep related movement disorders Both 733 1865 6 neurological darkblue 1865, 733 467, 198 466, 173 466, 194 466, 168 -0.0578 0.0433 0.182 0.7394 0.944 0.867 1.03 -0.131 0.124 0.291 0.5356 0.878 0.689 1.12 -0.0246 0.121 0.839 0.07636 0.976 0.769 1.24 -0.157 0.125 0.206 0.6852 0.854 0.669 1.09 PRS_PLINK_2.51188643150958e.06 FALSE 327.71 Restless legs syndrome Both 630 1639 6 neurological darkblue 1639, 630 410, 171 410, 146 409, 166 410, 147 -0.0567 0.0467 0.224 0.65 0.945 0.862 1.04 -0.144 0.133 0.279 0.5546 0.866 0.666 1.12 -0.0331 0.13 0.799 0.09721 0.967 0.749 1.25 -0.14 0.133 0.295 0.5309 0.869 0.669 1.13 PRS_PLINK_2.51188643150958e.06 FALSE 327.72 Sleep related leg cramps Both 39 99 6 neurological darkblue 99, 39 25, 13 25, 6 24, 12 25, 8 -0.324 0.221 0.141 0.8498 0.723 0.469 1.11 -0.761 0.649 0.241 0.6171 0.467 0.131 1.67 0.0878 0.523 0.867 0.06212 1.09 0.392 3.04 -0.317 0.555 0.568 0.2459 0.728 0.245 2.16 PRS_PLINK_2.51188643150958e.06 TRUE 331 Other cerebral degenerations Both 293 908 6 neurological darkblue 908, 293 227, 81 227, 67 227, 73 227, 72 -0.0379 0.0695 0.586 0.2324 0.963 0.84 1.1 -0.178 0.193 0.355 0.4496 0.837 0.573 1.22 -0.158 0.192 0.411 0.386 0.854 0.586 1.24 -0.081 0.191 0.672 0.1724 0.922 0.634 1.34 PRS_PLINK_2.51188643150958e.06 FALSE 331.1 Hydrocephalus Both 67 314 6 neurological darkblue 314, 67 79, 22 78, 13 78, 9 79, 23 0.057 0.157 0.716 0.1452 1.06 0.779 1.44 -0.434 0.388 0.263 0.5808 0.648 0.303 1.38 -0.778 0.432 0.0717 1.144 0.459 0.197 1.07 0.0663 0.367 0.857 0.06713 1.07 0.52 2.19 PRS_PLINK_2.51188643150958e.06 FALSE 331.9 Cerebral degeneration, unspecified Both 216 557 6 neurological darkblue 557, 216 140, 56 139, 47 139, 61 139, 52 -0.0124 0.0814 0.879 0.05596 0.988 0.842 1.16 -0.176 0.233 0.45 0.3466 0.839 0.532 1.32 0.00392 0.229 0.986 0.005981 1 0.641 1.57 -0.0359 0.232 0.877 0.05706 0.965 0.613 1.52 PRS_PLINK_2.51188643150958e.06 FALSE 332 Parkinson's disease Both 157 523 6 neurological darkblue 523, 157 131, 35 131, 40 130, 48 131, 34 0.0945 0.109 0.388 0.4114 1.1 0.887 1.36 0.135 0.266 0.612 0.2133 1.14 0.68 1.93 0.337 0.255 0.187 0.7289 1.4 0.85 2.31 -0.00837 0.274 0.976 0.01072 0.992 0.58 1.7 PRS_PLINK_2.51188643150958e.06 FALSE 333 Extrapyramidal disease and abnormal movement disorders Both 1145 3360 6 neurological darkblue 3360, 1145 839, 296 840, 291 840, 293 840, 265 0.0034 0.0345 0.922 0.03549 1 0.938 1.07 -0.0152 0.0961 0.874 0.05844 0.985 0.816 1.19 -0.0122 0.0961 0.899 0.04629 0.988 0.818 1.19 -0.111 0.0981 0.256 0.5921 0.895 0.738 1.08 PRS_PLINK_2.51188643150958e.06 FALSE 333.1 Essential tremor Both 310 940 6 neurological darkblue 940, 310 235, 87 235, 88 235, 63 235, 72 -0.0103 0.0718 0.886 0.05249 0.99 0.86 1.14 0.011 0.179 0.951 0.02188 1.01 0.712 1.44 -0.358 0.192 0.0621 1.207 0.699 0.48 1.02 -0.217 0.185 0.241 0.6176 0.805 0.559 1.16 PRS_PLINK_2.51188643150958e.06 FALSE 333.2 Myoclonus Both 83 194 6 neurological darkblue 194, 83 49, 21 48, 18 48, 27 49, 17 0.0467 0.124 0.705 0.1516 1.05 0.822 1.33 -0.179 0.401 0.655 0.1839 0.836 0.381 1.83 0.13 0.372 0.727 0.1387 1.14 0.549 2.36 -0.174 0.401 0.665 0.1772 0.841 0.383 1.84 PRS_PLINK_2.51188643150958e.06 FALSE 333.4 Torsion dystonia Both 130 416 6 neurological darkblue 416, 130 104, 30 104, 28 104, 26 104, 46 0.142 0.108 0.186 0.7316 1.15 0.934 1.42 -0.0329 0.301 0.913 0.03945 0.968 0.536 1.75 -0.145 0.302 0.63 0.2004 0.865 0.479 1.56 0.443 0.28 0.114 0.9446 1.56 0.9 2.7 PRS_PLINK_2.51188643150958e.06 FALSE 333.8 Other degenerative diseases of the basal ganglia Both 47 122 6 neurological darkblue 122, 47 31, 8 30, 14 30, 9 31, 16 -0.0423 0.173 0.807 0.09331 0.959 0.683 1.35 0.683 0.532 0.199 0.7003 1.98 0.698 5.62 0.186 0.559 0.74 0.131 1.2 0.403 3.6 0.534 0.51 0.295 0.5296 1.71 0.628 4.63 PRS_PLINK_2.51188643150958e.06 TRUE 334 Degenerative disease of the spinal cord Both 379 1243 6 neurological darkblue 1243, 379 311, 106 311, 93 310, 105 311, 75 -0.0676 0.0526 0.198 0.7024 0.935 0.843 1.04 -0.109 0.165 0.507 0.2946 0.897 0.649 1.24 0.0116 0.162 0.943 0.02546 1.01 0.736 1.39 -0.329 0.172 0.0556 1.255 0.719 0.514 1.01 PRS_PLINK_2.51188643150958e.06 FALSE 334.1 Spinocerebellar disease Both 34 112 6 neurological darkblue 112, 34 28, 6 28, 9 28, 9 28, 10 0.0713 0.251 0.776 0.1099 1.07 0.656 1.76 0.334 0.59 0.571 0.2431 1.4 0.44 4.43 0.25 0.599 0.677 0.1695 1.28 0.397 4.15 0.418 0.621 0.501 0.3003 1.52 0.45 5.13 PRS_PLINK_2.51188643150958e.06 TRUE 334.2 Anterior horn cell disease Both 51 129 6 neurological darkblue 129, 51 33, 10 32, 10 32, 11 32, 20 0.212 0.168 0.205 0.6873 1.24 0.89 1.72 0.0413 0.552 0.94 0.0267 1.04 0.353 3.08 0.284 0.553 0.608 0.2164 1.33 0.449 3.93 0.761 0.512 0.137 0.862 2.14 0.784 5.84 PRS_PLINK_2.51188643150958e.06 FALSE 334.21 Amyotrophic Lateral Sclerosis Both 34 70 6 neurological darkblue 70, 34 18, 7 17, 8 17, 6 18, 13 0.123 0.225 0.583 0.2342 1.13 0.728 1.76 0.355 0.793 0.654 0.1842 1.43 0.301 6.75 -0.052 0.722 0.943 0.02567 0.949 0.231 3.91 0.423 0.671 0.528 0.2772 1.53 0.41 5.69 PRS_PLINK_2.51188643150958e.06 TRUE 335 Multiple sclerosis Both 161 449 6 neurological darkblue 449, 161 113, 47 112, 42 112, 34 112, 38 -0.0626 0.0819 0.444 0.3523 0.939 0.8 1.1 -0.0559 0.259 0.829 0.08158 0.946 0.57 1.57 -0.277 0.266 0.297 0.5271 0.758 0.45 1.28 -0.157 0.26 0.545 0.2635 0.854 0.513 1.42 PRS_PLINK_2.51188643150958e.06 FALSE 337 Disorders of the autonomic nervous system Both 353 1051 6 neurological darkblue 1051, 353 263, 92 263, 89 262, 97 263, 75 0.0135 0.0627 0.829 0.08143 1.01 0.896 1.15 -0.0321 0.174 0.853 0.06892 0.968 0.689 1.36 0.0667 0.171 0.696 0.1575 1.07 0.765 1.49 -0.184 0.18 0.305 0.5154 0.832 0.585 1.18 PRS_PLINK_2.51188643150958e.06 FALSE 337.1 Peripheral autonomic neuropathy Both 203 547 6 neurological darkblue 547, 203 137, 52 137, 49 136, 63 137, 39 0.0513 0.0832 0.537 0.2697 1.05 0.894 1.24 -0.0422 0.235 0.858 0.0667 0.959 0.604 1.52 0.222 0.228 0.33 0.481 1.25 0.798 1.95 -0.188 0.249 0.45 0.3471 0.829 0.509 1.35 PRS_PLINK_2.51188643150958e.06 FALSE 338 Pain Both 4835 2615 6 neurological darkblue 2615, 4835 653, 1169 654, 1212 653, 1260 654, 1194 0.0228 0.0244 0.35 0.4563 1.02 0.975 1.07 0.0224 0.0698 0.749 0.1257 1.02 0.892 1.17 0.0672 0.0695 0.334 0.4768 1.07 0.933 1.23 0.0299 0.07 0.669 0.1748 1.03 0.898 1.18 PRS_PLINK_2.51188643150958e.06 FALSE 338.1 Acute pain Both 3563 2610 6 neurological darkblue 2610, 3563 652, 853 652, 897 652, 914 653, 899 0.0235 0.0257 0.36 0.4433 1.02 0.973 1.08 0.0469 0.0744 0.528 0.2772 1.05 0.906 1.21 0.0588 0.0742 0.428 0.3685 1.06 0.917 1.23 0.0594 0.0745 0.425 0.3713 1.06 0.917 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 338.2 Chronic pain Both 3407 2606 6 neurological darkblue 2606, 3407 651, 835 651, 854 651, 874 652, 844 0.0239 0.0263 0.365 0.4377 1.02 0.973 1.08 0.0121 0.0749 0.871 0.05983 1.01 0.874 1.17 0.0447 0.0746 0.549 0.2605 1.05 0.904 1.21 0.0227 0.0751 0.762 0.118 1.02 0.883 1.19 PRS_PLINK_2.51188643150958e.06 FALSE 339 Other headache syndromes Both 2815 4120 6 neurological darkblue 4120, 2815 1029, 697 1030, 694 1030, 663 1030, 761 0.0334 0.0256 0.193 0.7155 1.03 0.983 1.09 -0.0177 0.0724 0.807 0.09321 0.982 0.852 1.13 -0.0552 0.0729 0.449 0.3479 0.946 0.82 1.09 0.0806 0.0719 0.263 0.5809 1.08 0.941 1.25 PRS_PLINK_2.51188643150958e.06 FALSE 340 Migraine Both 1968 3573 6 neurological darkblue 3573, 1968 894, 500 893, 480 893, 459 893, 529 0.0286 0.0295 0.333 0.4774 1.03 0.971 1.09 -0.056 0.0834 0.502 0.2994 0.946 0.803 1.11 -0.0888 0.0836 0.288 0.5404 0.915 0.777 1.08 0.0517 0.082 0.528 0.2773 1.05 0.897 1.24 PRS_PLINK_2.51188643150958e.06 FALSE 340.1 Migrain with aura Both 1148 2798 6 neurological darkblue 2798, 1148 700, 289 699, 275 699, 254 700, 330 0.0591 0.0368 0.108 0.9669 1.06 0.987 1.14 -0.0533 0.102 0.602 0.2205 0.948 0.776 1.16 -0.131 0.103 0.202 0.6939 0.877 0.717 1.07 0.125 0.0989 0.208 0.6824 1.13 0.933 1.37 PRS_PLINK_2.51188643150958e.06 FALSE 341 Other demyelinating diseases of central nervous system Both 72 151 6 neurological darkblue 151, 72 38, 34 38, 8 37, 13 38, 17 -0.229 0.136 0.0924 1.035 0.795 0.609 1.04 -1.38 0.484 0.00441 2.356 0.252 0.0976 0.651 -1.02 0.435 0.0189 1.723 0.361 0.154 0.845 -0.569 0.395 0.15 0.8247 0.566 0.261 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 342 Hemiplegia Both 174 585 6 neurological darkblue 585, 174 147, 50 146, 25 146, 46 146, 53 0.182 0.0909 0.0453 1.344 1.2 1 1.43 -0.624 0.274 0.023 1.639 0.536 0.313 0.917 -0.0549 0.236 0.816 0.08811 0.947 0.595 1.5 0.0271 0.234 0.908 0.04198 1.03 0.65 1.62 PRS_PLINK_2.51188643150958e.06 FALSE 343 Infantile cerebral palsy Both 15 90 6 neurological darkblue 90, 15 23, 3 22, 5 22, 3 23, 4 0.125 0.254 0.622 0.206 1.13 0.689 1.87 0.84 0.842 0.318 0.497 2.32 0.445 12 0.199 1.01 0.844 0.07359 1.22 0.167 8.91 -0.226 0.951 0.812 0.09053 0.797 0.124 5.14 PRS_PLINK_2.51188643150958e.06 TRUE 344 Other paralytic syndromes Both 273 746 6 neurological darkblue 746, 273 187, 73 186, 62 186, 73 187, 65 -0.0274 0.0746 0.714 0.1466 0.973 0.841 1.13 -0.152 0.205 0.46 0.3376 0.859 0.575 1.28 -0.0273 0.197 0.89 0.05076 0.973 0.661 1.43 -0.141 0.201 0.485 0.3145 0.869 0.585 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 345 Epilepsy, recurrent seizures, convulsions Both 724 2987 6 neurological darkblue 2987, 724 747, 178 747, 172 746, 199 747, 175 0.0156 0.0412 0.705 0.152 1.02 0.937 1.1 -0.0192 0.119 0.872 0.05957 0.981 0.777 1.24 0.0983 0.116 0.396 0.4024 1.1 0.879 1.38 -0.0208 0.119 0.861 0.06505 0.979 0.776 1.24 PRS_PLINK_2.51188643150958e.06 FALSE 345.1 Epilepsy Both 230 917 6 neurological darkblue 917, 230 230, 68 229, 47 229, 73 229, 42 -0.137 0.0679 0.0445 1.352 0.872 0.764 0.997 -0.354 0.211 0.0937 1.028 0.702 0.464 1.06 0.0426 0.194 0.826 0.08284 1.04 0.713 1.53 -0.471 0.216 0.0293 1.533 0.624 0.409 0.954 PRS_PLINK_2.51188643150958e.06 FALSE 345.11 Generalized convulsive epilepsy Both 57 268 6 neurological darkblue 268, 57 67, 18 67, 13 67, 14 67, 12 -0.186 0.122 0.128 0.8925 0.83 0.653 1.06 -0.447 0.405 0.27 0.5692 0.639 0.289 1.41 -0.246 0.399 0.537 0.2696 0.782 0.358 1.71 -0.415 0.421 0.324 0.4898 0.66 0.289 1.51 PRS_PLINK_2.51188643150958e.06 FALSE 345.12 Partial epilepsy Both 169 654 6 neurological darkblue 654, 169 164, 47 163, 32 163, 53 164, 37 -0.0894 0.0775 0.249 0.6041 0.915 0.786 1.06 -0.356 0.254 0.161 0.7922 0.701 0.426 1.15 0.0702 0.233 0.763 0.1175 1.07 0.68 1.69 -0.224 0.244 0.36 0.4439 0.8 0.496 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 345.3 Convulsions Both 682 2815 6 neurological darkblue 2815, 682 704, 169 704, 161 703, 188 704, 164 0.0157 0.0422 0.709 0.1491 1.02 0.935 1.1 -0.0346 0.123 0.778 0.1092 0.966 0.76 1.23 0.0902 0.119 0.449 0.3479 1.09 0.867 1.38 -0.0309 0.122 0.801 0.09653 0.97 0.763 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 346 Abnormal findings on study of brain and/or nervous system Both 84 228 6 neurological darkblue 228, 84 57, 26 57, 22 57, 19 57, 17 -0.0356 0.124 0.774 0.1113 0.965 0.757 1.23 -0.168 0.354 0.636 0.1965 0.846 0.422 1.69 -0.391 0.368 0.287 0.5419 0.676 0.329 1.39 -0.414 0.371 0.265 0.5761 0.661 0.319 1.37 PRS_PLINK_2.51188643150958e.06 FALSE 346.1 Nonspecific abnormal findings on radiological and other examination of skull and head Both 582 1856 6 neurological darkblue 1856, 582 464, 152 464, 135 464, 156 464, 139 -0.00196 0.0467 0.967 0.0148 0.998 0.911 1.09 -0.108 0.136 0.427 0.37 0.898 0.688 1.17 0.0308 0.133 0.816 0.08815 1.03 0.795 1.34 -0.0797 0.136 0.557 0.2539 0.923 0.708 1.2 PRS_PLINK_2.51188643150958e.06 FALSE 346.2 Nonspecific abnormal results of function study of brain and central nervous system Both 59 141 6 neurological darkblue 141, 59 36, 14 35, 15 35, 18 35, 12 -0.0075 0.148 0.96 0.01795 0.993 0.743 1.33 0.077 0.46 0.867 0.06199 1.08 0.439 2.66 0.149 0.447 0.739 0.1315 1.16 0.484 2.79 -0.129 0.46 0.779 0.1087 0.879 0.357 2.16 PRS_PLINK_2.51188643150958e.06 FALSE 346.3 Nonspecific abnormal findings in cerebrospinal fluid Both 52 143 6 neurological darkblue 143, 52 36, 15 36, 12 35, 15 36, 10 -0.11 0.157 0.482 0.3165 0.896 0.658 1.22 -0.339 0.499 0.497 0.3037 0.712 0.268 1.9 -0.377 0.504 0.455 0.3424 0.686 0.255 1.84 -0.344 0.473 0.467 0.3309 0.709 0.28 1.79 PRS_PLINK_2.51188643150958e.06 FALSE 347 Cataplexy and narcolepsy Both 32 125 6 neurological darkblue 125, 32 32, 7 31, 9 31, 5 31, 11 0.256 0.201 0.204 0.691 1.29 0.87 1.92 0.553 0.625 0.376 0.4249 1.74 0.511 5.92 -0.0205 0.639 0.974 0.01124 0.98 0.28 3.43 0.264 0.582 0.65 0.1868 1.3 0.416 4.07 PRS_PLINK_2.51188643150958e.06 TRUE 348 Other conditions of brain Both 589 2144 6 neurological darkblue 2144, 589 536, 149 536, 135 536, 166 536, 139 0.0218 0.0465 0.64 0.1939 1.02 0.933 1.12 -0.0781 0.134 0.561 0.2507 0.925 0.711 1.2 0.119 0.129 0.356 0.448 1.13 0.874 1.45 -0.0635 0.134 0.635 0.1974 0.939 0.722 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 348.2 Cerebral edema and compression of brain Both 193 1005 6 neurological darkblue 1005, 193 251, 55 251, 44 251, 52 251, 42 -0.0111 0.0769 0.885 0.05317 0.989 0.851 1.15 -0.199 0.222 0.37 0.4322 0.82 0.531 1.27 -0.00784 0.215 0.971 0.01284 0.992 0.651 1.51 -0.246 0.226 0.276 0.5585 0.782 0.502 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 348.4 Cerebral cysts Both 66 286 6 neurological darkblue 286, 66 72, 19 71, 15 71, 19 72, 13 -0.173 0.124 0.162 0.7896 0.841 0.66 1.07 0.0336 0.411 0.935 0.02932 1.03 0.463 2.31 -0.0867 0.376 0.818 0.08737 0.917 0.439 1.92 -0.365 0.403 0.365 0.4379 0.694 0.315 1.53 PRS_PLINK_2.51188643150958e.06 FALSE 348.7 Coma Both 96 277 6 neurological darkblue 277, 96 70, 28 69, 25 69, 25 69, 18 -0.274 0.128 0.0319 1.496 0.761 0.592 0.977 -0.122 0.333 0.715 0.146 0.885 0.461 1.7 -0.324 0.346 0.348 0.4583 0.723 0.367 1.42 -0.529 0.374 0.157 0.8041 0.589 0.283 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 348.8 Encephalopathy, not elsewhere classified Both 380 1029 6 neurological darkblue 1029, 380 258, 95 257, 75 257, 107 257, 103 0.0832 0.0622 0.181 0.7433 1.09 0.962 1.23 -0.216 0.18 0.229 0.6402 0.805 0.566 1.15 0.138 0.169 0.412 0.3849 1.15 0.825 1.6 0.0696 0.171 0.683 0.1653 1.07 0.767 1.5 PRS_PLINK_2.51188643150958e.06 FALSE 348.9 Other conditions of brain, NOS Both 690 2770 6 neurological darkblue 2770, 690 693, 191 692, 155 692, 177 693, 167 -0.000577 0.0429 0.989 0.004688 0.999 0.919 1.09 -0.185 0.121 0.128 0.8923 0.831 0.655 1.05 -0.0684 0.119 0.565 0.2477 0.934 0.74 1.18 -0.108 0.12 0.366 0.4362 0.898 0.71 1.13 PRS_PLINK_2.51188643150958e.06 FALSE 349 Other and unspecified disorders of the nervous system Both 331 1132 6 neurological darkblue 1132, 331 283, 86 283, 77 283, 86 283, 82 0.0588 0.0638 0.357 0.4476 1.06 0.936 1.2 -0.0694 0.18 0.7 0.1551 0.933 0.656 1.33 0.0334 0.176 0.85 0.0708 1.03 0.732 1.46 -0.00053 0.178 0.998 0.001033 0.999 0.705 1.42 PRS_PLINK_2.51188643150958e.06 FALSE 350 Abnormal movement Both 2618 4702 6 neurological darkblue 4702, 2618 1175, 704 1175, 656 1175, 614 1176, 644 -0.00133 0.0251 0.958 0.01877 0.999 0.951 1.05 -0.0795 0.07 0.256 0.5914 0.924 0.805 1.06 -0.138 0.0712 0.0523 1.282 0.871 0.758 1 -0.0759 0.0706 0.282 0.5491 0.927 0.807 1.06 PRS_PLINK_2.51188643150958e.06 FALSE 350.1 Abnormal involuntary movements Both 1380 3818 6 neurological darkblue 3818, 1380 954, 366 954, 329 954, 361 955, 324 0.00591 0.0319 0.853 0.06905 1.01 0.945 1.07 -0.098 0.0891 0.271 0.5665 0.907 0.761 1.08 -0.00431 0.0879 0.961 0.01735 0.996 0.838 1.18 -0.12 0.0897 0.18 0.7438 0.887 0.744 1.06 PRS_PLINK_2.51188643150958e.06 FALSE 350.2 Abnormality of gait Both 1648 3814 6 neurological darkblue 3814, 1648 953, 484 953, 411 953, 350 954, 403 -0.0425 0.0296 0.151 0.8196 0.958 0.904 1.02 -0.185 0.0828 0.0255 1.594 0.831 0.707 0.978 -0.324 0.0862 0.000168 3.776 0.723 0.611 0.856 -0.169 0.0837 0.043 1.367 0.844 0.717 0.995 PRS_PLINK_2.51188643150958e.06 FALSE 350.3 Lack of coordination Both 447 1324 6 neurological darkblue 1324, 447 330, 132 331, 106 331, 95 331, 114 0.0027 0.0542 0.96 0.0176 1 0.902 1.12 -0.231 0.153 0.131 0.8837 0.794 0.589 1.07 -0.334 0.157 0.0333 1.477 0.716 0.527 0.974 -0.166 0.152 0.275 0.5601 0.847 0.629 1.14 PRS_PLINK_2.51188643150958e.06 FALSE 350.5 Abnormal reflex Both 86 258 6 neurological darkblue 258, 86 65, 22 64, 26 64, 22 65, 16 -0.0307 0.126 0.807 0.09302 0.97 0.758 1.24 0.107 0.357 0.764 0.117 1.11 0.553 2.24 -0.0335 0.362 0.926 0.03334 0.967 0.476 1.96 -0.36 0.393 0.36 0.4438 0.698 0.323 1.51 PRS_PLINK_2.51188643150958e.06 FALSE 350.6 Disturbances of sensation of smell and taste Both 149 691 6 neurological darkblue 691, 149 173, 32 173, 39 172, 44 173, 34 0.0344 0.0993 0.729 0.1373 1.03 0.852 1.26 0.217 0.259 0.403 0.3951 1.24 0.747 2.07 0.343 0.258 0.183 0.7368 1.41 0.85 2.34 0.0803 0.272 0.768 0.1146 1.08 0.636 1.85 PRS_PLINK_2.51188643150958e.06 FALSE 351 Other peripheral nerve disorders Both 2797 3778 6 neurological darkblue 3778, 2797 945, 646 944, 723 944, 734 945, 693 0.0292 0.0255 0.252 0.5983 1.03 0.979 1.08 0.101 0.0723 0.163 0.7887 1.11 0.96 1.27 0.14 0.0722 0.0532 1.274 1.15 0.998 1.32 0.086 0.0727 0.237 0.6257 1.09 0.945 1.26 PRS_PLINK_2.51188643150958e.06 FALSE 352 Disorders of other cranial nerves Both 411 1930 6 neurological darkblue 1930, 411 483, 96 482, 111 482, 106 483, 98 -0.0355 0.0536 0.508 0.2945 0.965 0.869 1.07 0.139 0.154 0.366 0.437 1.15 0.85 1.55 0.102 0.156 0.514 0.2894 1.11 0.816 1.5 0.00646 0.158 0.967 0.0144 1.01 0.738 1.37 PRS_PLINK_2.51188643150958e.06 FALSE 352.1 Trigeminal nerve disorders [CN5] Both 191 636 6 neurological darkblue 636, 191 159, 54 159, 40 159, 52 159, 45 -0.0711 0.0827 0.39 0.4091 0.931 0.792 1.1 -0.277 0.239 0.247 0.6076 0.758 0.474 1.21 0.00393 0.229 0.986 0.00599 1 0.641 1.57 -0.143 0.233 0.538 0.2691 0.867 0.549 1.37 PRS_PLINK_2.51188643150958e.06 FALSE 352.2 Facial nerve disorders [CN7] Both 190 878 6 neurological darkblue 878, 190 220, 37 219, 58 219, 48 220, 47 -0.00792 0.0786 0.92 0.03633 0.992 0.85 1.16 0.441 0.229 0.0544 1.264 1.55 0.992 2.44 0.279 0.237 0.238 0.6227 1.32 0.831 2.1 0.231 0.239 0.333 0.4772 1.26 0.789 2.01 PRS_PLINK_2.51188643150958e.06 FALSE 353 Nerve root and plexus disorders Both 1388 3684 6 neurological darkblue 3684, 1388 921, 329 921, 368 921, 323 921, 368 0.0359 0.0323 0.266 0.5746 1.04 0.973 1.1 0.113 0.0901 0.21 0.6775 1.12 0.938 1.34 -0.00601 0.0919 0.948 0.02326 0.994 0.83 1.19 0.149 0.0903 0.0992 1.003 1.16 0.972 1.39 PRS_PLINK_2.51188643150958e.06 FALSE 353.1 Nerve plexus lesions Both 114 425 6 neurological darkblue 425, 114 107, 28 106, 29 106, 24 106, 33 0.00698 0.107 0.948 0.0232 1.01 0.816 1.24 0.146 0.308 0.636 0.1967 1.16 0.632 2.12 -0.115 0.313 0.712 0.1474 0.891 0.483 1.64 0.19 0.296 0.522 0.2827 1.21 0.676 2.16 PRS_PLINK_2.51188643150958e.06 FALSE 353.2 Nerve root lesions Both 36 151 6 neurological darkblue 151, 36 38, 8 38, 11 37, 10 38, 7 0.0346 0.196 0.86 0.06565 1.04 0.705 1.52 0.434 0.52 0.404 0.3935 1.54 0.557 4.28 0.082 0.533 0.878 0.05667 1.09 0.382 3.09 -0.589 0.668 0.378 0.4223 0.555 0.15 2.06 PRS_PLINK_2.51188643150958e.06 TRUE 355 Complex regional/central pain syndrome Both 206 612 6 neurological darkblue 612, 206 153, 61 153, 55 153, 48 153, 42 -0.137 0.0806 0.0899 1.046 0.872 0.745 1.02 -0.129 0.221 0.559 0.2529 0.879 0.57 1.36 -0.154 0.229 0.501 0.3001 0.857 0.547 1.34 -0.309 0.235 0.19 0.7221 0.734 0.463 1.16 PRS_PLINK_2.51188643150958e.06 FALSE 355.1 Chronic pain syndrome Both 437 953 6 neurological darkblue 953, 437 239, 92 238, 98 238, 133 238, 114 0.146 0.062 0.0187 1.728 1.16 1.02 1.31 0.0666 0.173 0.701 0.1544 1.07 0.761 1.5 0.401 0.167 0.0162 1.791 1.49 1.08 2.07 0.258 0.171 0.131 0.8825 1.29 0.926 1.81 PRS_PLINK_2.51188643150958e.06 FALSE 356 Hereditary and idiopathic peripheral neuropathy Both 1263 2782 6 neurological darkblue 2782, 1263 696, 315 695, 311 695, 335 696, 301 0.0332 0.0337 0.324 0.4893 1.03 0.968 1.1 0.00488 0.0975 0.96 0.0177 1 0.83 1.22 0.0822 0.0963 0.393 0.4052 1.09 0.899 1.31 -0.0414 0.0984 0.674 0.1713 0.959 0.791 1.16 PRS_PLINK_2.51188643150958e.06 FALSE 357 Inflammatory and toxic neuropathy Both 1662 3881 6 neurological darkblue 3881, 1662 971, 409 970, 434 970, 416 970, 402 0.00727 0.0298 0.807 0.09292 1.01 0.95 1.07 0.0721 0.0836 0.388 0.4109 1.07 0.912 1.27 0.0373 0.0843 0.658 0.1816 1.04 0.88 1.22 -0.0195 0.0853 0.819 0.08649 0.981 0.83 1.16 PRS_PLINK_2.51188643150958e.06 FALSE 358 Myoneural disorders Both 515 1545 6 neurological darkblue 1545, 515 387, 147 386, 105 386, 127 386, 136 6.1e-05 0.0532 0.999 0.0003982 1 0.901 1.11 -0.341 0.148 0.021 1.678 0.711 0.532 0.95 -0.143 0.143 0.315 0.5011 0.867 0.655 1.15 -0.0756 0.141 0.592 0.2277 0.927 0.703 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 358.1 Myasthenia gravis Both 42 145 6 neurological darkblue 145, 42 37, 12 36, 10 36, 8 36, 12 -0.073 0.179 0.684 0.165 0.93 0.654 1.32 -0.224 0.512 0.662 0.1791 0.8 0.293 2.18 -0.361 0.517 0.485 0.3143 0.697 0.253 1.92 0.106 0.509 0.834 0.0786 1.11 0.41 3.01 PRS_PLINK_2.51188643150958e.06 TRUE 359 Muscular dystrophies and other myopathies Both 465 1528 6 neurological darkblue 1528, 465 382, 118 382, 113 382, 107 382, 127 0.0431 0.0542 0.426 0.3705 1.04 0.939 1.16 -0.0215 0.151 0.887 0.05227 0.979 0.728 1.32 -0.0753 0.153 0.623 0.2054 0.927 0.687 1.25 0.0709 0.148 0.631 0.1999 1.07 0.804 1.43 PRS_PLINK_2.51188643150958e.06 FALSE 359.1 Muscular dystrophies Both 21 81 6 neurological darkblue 81, 21 21, 6 20, 7 20, 4 20, 4 -0.206 0.285 0.469 0.3291 0.814 0.466 1.42 -0.257 0.7 0.714 0.1466 0.773 0.196 3.05 -0.0586 0.791 0.941 0.02646 0.943 0.2 4.44 -0.0395 0.763 0.959 0.01829 0.961 0.215 4.29 PRS_PLINK_2.51188643150958e.06 TRUE 359.2 Myopathy Both 452 1474 6 neurological darkblue 1474, 452 369, 112 368, 110 368, 107 369, 123 0.054 0.0547 0.324 0.49 1.06 0.948 1.17 0.00146 0.154 0.992 0.003303 1 0.741 1.35 -0.0222 0.156 0.887 0.05218 0.978 0.72 1.33 0.0907 0.151 0.548 0.2615 1.09 0.815 1.47 PRS_PLINK_2.51188643150958e.06 FALSE 360 Disorders of the globe Both 52 205 7 sense organs darkseagreen4 205, 52 52, 13 51, 13 51, 12 51, 14 -0.0702 0.154 0.648 0.1885 0.932 0.69 1.26 -0.0339 0.462 0.941 0.0262 0.967 0.391 2.39 0.0757 0.491 0.877 0.05676 1.08 0.412 2.83 0.185 0.449 0.68 0.1673 1.2 0.499 2.9 PRS_PLINK_2.51188643150958e.06 FALSE 360.2 Progressive myopia Both 27 92 7 sense organs darkseagreen4 92, 27 23, 6 23, 7 23, 10 23, 4 -0.0676 0.219 0.758 0.1205 0.935 0.608 1.44 0.453 0.687 0.51 0.2926 1.57 0.409 6.05 0.934 0.682 0.171 0.7678 2.54 0.669 9.68 -0.154 0.741 0.835 0.07808 0.857 0.2 3.67 PRS_PLINK_2.51188643150958e.06 TRUE 361 Retinal detachments and defects Both 227 1046 7 sense organs darkseagreen4 1046, 227 262, 61 261, 60 261, 64 262, 41 -0.0705 0.0684 0.303 0.5192 0.932 0.815 1.07 -0.0117 0.203 0.954 0.02039 0.988 0.664 1.47 0.0921 0.202 0.648 0.1887 1.1 0.739 1.63 -0.405 0.22 0.0657 1.183 0.667 0.434 1.03 PRS_PLINK_2.51188643150958e.06 FALSE 361.1 Retinal detachment with retinal defect Both 90 466 7 sense organs darkseagreen4 466, 90 117, 20 116, 27 116, 28 117, 15 -0.0442 0.117 0.705 0.1516 0.957 0.761 1.2 0.328 0.323 0.309 0.5096 1.39 0.737 2.61 0.43 0.324 0.184 0.7345 1.54 0.815 2.9 -0.311 0.362 0.39 0.4092 0.732 0.36 1.49 PRS_PLINK_2.51188643150958e.06 FALSE 362 Other retinal disorders Both 1351 3153 7 sense organs darkseagreen4 3153, 1351 789, 329 788, 356 788, 325 788, 340 0.0543 0.0337 0.107 0.9695 1.06 0.988 1.13 0.0913 0.0949 0.336 0.4733 1.1 0.91 1.32 0.0222 0.0963 0.817 0.08761 1.02 0.847 1.23 0.0687 0.095 0.47 0.3279 1.07 0.889 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 362.2 Degeneration of macula and posterior pole of retina Both 827 2207 7 sense organs darkseagreen4 2207, 827 552, 203 552, 220 551, 199 552, 204 0.0231 0.0416 0.578 0.238 1.02 0.943 1.11 0.119 0.119 0.314 0.5025 1.13 0.893 1.42 0.0182 0.12 0.879 0.05582 1.02 0.805 1.29 0.0166 0.119 0.889 0.05087 1.02 0.804 1.28 PRS_PLINK_2.51188643150958e.06 FALSE 362.21 Macular degeneration, dry Both 203 521 7 sense organs darkseagreen4 521, 203 131, 51 130, 66 130, 43 130, 43 0.0641 0.0881 0.467 0.3306 1.07 0.897 1.27 0.358 0.237 0.131 0.8811 1.43 0.898 2.28 -0.131 0.248 0.599 0.2229 0.877 0.539 1.43 -0.0707 0.261 0.786 0.1044 0.932 0.559 1.55 PRS_PLINK_2.51188643150958e.06 FALSE 362.22 Macular degeneration, wet Both 66 207 7 sense organs darkseagreen4 207, 66 52, 16 52, 27 51, 13 52, 10 -0.042 0.148 0.776 0.1101 0.959 0.718 1.28 0.68 0.395 0.0855 1.068 1.97 0.909 4.28 -0.227 0.443 0.608 0.2158 0.797 0.334 1.9 -0.278 0.489 0.57 0.2443 0.757 0.29 1.98 PRS_PLINK_2.51188643150958e.06 FALSE 362.23 Cystoid macular degeneration of retina Both 155 549 7 sense organs darkseagreen4 549, 155 138, 42 137, 34 137, 49 137, 29 -0.0379 0.089 0.67 0.1737 0.963 0.809 1.15 -0.188 0.265 0.48 0.3188 0.829 0.493 1.39 0.243 0.25 0.331 0.4802 1.27 0.781 2.08 -0.36 0.27 0.182 0.7397 0.698 0.411 1.18 PRS_PLINK_2.51188643150958e.06 FALSE 362.26 Macular puckering of retina Both 370 1289 7 sense organs darkseagreen4 1289, 370 323, 93 322, 104 322, 89 322, 83 -0.0728 0.0574 0.204 0.6896 0.93 0.831 1.04 0.129 0.166 0.434 0.3621 1.14 0.823 1.57 -0.000455 0.171 0.998 0.0009231 1 0.715 1.4 -0.0981 0.173 0.571 0.2431 0.907 0.646 1.27 PRS_PLINK_2.51188643150958e.06 FALSE 362.27 Drusen (degenerative) of retina Both 200 706 7 sense organs darkseagreen4 706, 200 177, 37 176, 54 176, 55 177, 54 0.163 0.0899 0.0704 1.153 1.18 0.987 1.4 0.345 0.243 0.157 0.8045 1.41 0.876 2.27 0.396 0.24 0.0992 1.003 1.49 0.928 2.38 0.345 0.242 0.154 0.8128 1.41 0.879 2.27 PRS_PLINK_2.51188643150958e.06 FALSE 362.29 Macular degeneration (senile) of retina NOS Both 715 2007 7 sense organs darkseagreen4 2007, 715 502, 167 502, 194 501, 169 502, 184 0.0346 0.0446 0.437 0.3592 1.04 0.949 1.13 0.183 0.127 0.15 0.8241 1.2 0.936 1.54 0.0503 0.13 0.698 0.156 1.05 0.816 1.36 0.113 0.127 0.374 0.4272 1.12 0.872 1.44 PRS_PLINK_2.51188643150958e.06 FALSE 362.3 Other nondiabetic retinopathy Both 396 1270 7 sense organs darkseagreen4 1270, 396 318, 113 317, 97 317, 101 318, 84 -0.0715 0.0552 0.195 0.7093 0.931 0.835 1.04 -0.191 0.163 0.242 0.6169 0.826 0.6 1.14 -0.08 0.159 0.616 0.2104 0.923 0.675 1.26 -0.286 0.166 0.0854 1.068 0.751 0.542 1.04 PRS_PLINK_2.51188643150958e.06 FALSE 362.31 Separation of retinal layers Both 132 591 7 sense organs darkseagreen4 591, 132 148, 40 148, 30 147, 32 148, 29 -0.0977 0.0904 0.28 0.5536 0.907 0.76 1.08 -0.303 0.268 0.258 0.5884 0.739 0.437 1.25 -0.249 0.269 0.356 0.4484 0.78 0.46 1.32 -0.332 0.27 0.219 0.6597 0.717 0.423 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 362.4 Retinal vascular changes and abnomalities Both 288 861 7 sense organs darkseagreen4 861, 288 216, 75 215, 92 215, 59 215, 62 -0.027 0.0721 0.708 0.15 0.973 0.845 1.12 0.211 0.185 0.254 0.5957 1.24 0.859 1.78 -0.21 0.202 0.298 0.5257 0.81 0.545 1.2 -0.181 0.198 0.361 0.443 0.835 0.567 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 362.6 Peripheral retinal degenerations Both 149 555 7 sense organs darkseagreen4 555, 149 139, 35 139, 38 138, 37 139, 39 0.0718 0.0981 0.464 0.3337 1.07 0.887 1.3 0.168 0.267 0.53 0.2761 1.18 0.701 1.99 0.0899 0.268 0.737 0.1325 1.09 0.647 1.85 0.101 0.264 0.703 0.1533 1.11 0.659 1.86 PRS_PLINK_2.51188643150958e.06 FALSE 362.7 Hereditary retinal dystrophies Both 70 329 7 sense organs darkseagreen4 329, 70 83, 22 82, 11 82, 18 82, 19 0.00153 0.12 0.99 0.004438 1 0.791 1.27 -0.539 0.401 0.179 0.7463 0.583 0.266 1.28 -0.23 0.361 0.523 0.2814 0.794 0.392 1.61 -0.146 0.357 0.682 0.1664 0.864 0.429 1.74 PRS_PLINK_2.51188643150958e.06 FALSE 362.8 Retinal hemorrhage/ischemia Both 105 369 7 sense organs darkseagreen4 369, 105 93, 20 92, 23 92, 39 92, 23 0.116 0.118 0.327 0.4848 1.12 0.89 1.42 0.187 0.338 0.579 0.2372 1.21 0.622 2.34 0.826 0.333 0.0131 1.883 2.28 1.19 4.38 0.167 0.348 0.631 0.2002 1.18 0.597 2.34 PRS_PLINK_2.51188643150958e.06 FALSE 362.9 Retinal edema Both 143 497 7 sense organs darkseagreen4 497, 143 125, 33 124, 37 124, 39 124, 34 0.0731 0.0956 0.444 0.3523 1.08 0.892 1.3 0.154 0.276 0.576 0.2398 1.17 0.679 2 0.165 0.278 0.553 0.2575 1.18 0.684 2.04 0.0159 0.278 0.954 0.02026 1.02 0.589 1.75 PRS_PLINK_2.51188643150958e.06 FALSE 363 Chorioretinal inflammations, scars, and other disorders of choroid Both 168 725 7 sense organs darkseagreen4 725, 168 182, 44 181, 49 181, 41 181, 33 -0.0705 0.0799 0.378 0.4228 0.932 0.797 1.09 0.13 0.234 0.579 0.237 1.14 0.72 1.8 -0.0462 0.241 0.848 0.07165 0.955 0.595 1.53 -0.271 0.254 0.286 0.5438 0.763 0.463 1.25 PRS_PLINK_2.51188643150958e.06 FALSE 363.3 Chorioretinal scars Both 121 498 7 sense organs darkseagreen4 498, 121 125, 31 124, 39 124, 25 125, 25 -0.119 0.0934 0.202 0.6951 0.888 0.739 1.07 0.216 0.276 0.434 0.3629 1.24 0.723 2.13 -0.157 0.3 0.601 0.2214 0.855 0.475 1.54 -0.241 0.299 0.421 0.3762 0.786 0.437 1.41 PRS_PLINK_2.51188643150958e.06 FALSE 364 Corneal opacity and other disorders of cornea Both 384 1613 7 sense organs darkseagreen4 1613, 384 404, 102 403, 81 403, 103 403, 98 0.0606 0.0611 0.321 0.4938 1.06 0.943 1.2 -0.198 0.166 0.234 0.63 0.821 0.592 1.14 0.0183 0.158 0.908 0.04194 1.02 0.747 1.39 0.00516 0.16 0.974 0.01131 1.01 0.734 1.38 PRS_PLINK_2.51188643150958e.06 FALSE 364.1 Corneal opacity Both 128 602 7 sense organs darkseagreen4 602, 128 151, 31 150, 29 150, 34 151, 34 0.0584 0.107 0.585 0.2331 1.06 0.86 1.31 -0.0959 0.289 0.74 0.1308 0.909 0.516 1.6 0.0542 0.278 0.845 0.07301 1.06 0.613 1.82 0.0939 0.275 0.733 0.135 1.1 0.641 1.88 PRS_PLINK_2.51188643150958e.06 FALSE 364.2 Corneal edema Both 37 163 7 sense organs darkseagreen4 163, 37 41, 9 41, 4 40, 12 41, 12 0.272 0.246 0.27 0.5684 1.31 0.81 2.13 -0.529 0.625 0.397 0.4007 0.589 0.173 2.01 0.367 0.516 0.478 0.3209 1.44 0.524 3.97 0.291 0.518 0.574 0.2408 1.34 0.485 3.69 PRS_PLINK_2.51188643150958e.06 TRUE 364.4 Corneal degenerations Both 121 620 7 sense organs darkseagreen4 620, 121 155, 34 155, 28 155, 26 155, 33 0.0366 0.101 0.717 0.1444 1.04 0.851 1.26 -0.21 0.279 0.452 0.3449 0.811 0.469 1.4 -0.233 0.29 0.423 0.3736 0.792 0.449 1.4 0.0233 0.271 0.931 0.03083 1.02 0.602 1.74 PRS_PLINK_2.51188643150958e.06 FALSE 364.41 Keratoconus Both 20 128 7 sense organs darkseagreen4 128, 20 32, 4 32, 3 32, 5 32, 8 0.242 0.292 0.408 0.3891 1.27 0.718 2.26 0.251 0.791 0.751 0.1243 1.29 0.273 6.05 -0.0397 0.862 0.963 0.01624 0.961 0.177 5.21 0.817 0.744 0.272 0.5652 2.26 0.527 9.73 PRS_PLINK_2.51188643150958e.06 TRUE 364.5 Corneal dystrophy Both 197 758 7 sense organs darkseagreen4 758, 197 190, 47 189, 40 189, 63 190, 47 0.118 0.0878 0.179 0.7479 1.13 0.947 1.34 -0.135 0.241 0.575 0.2405 0.873 0.544 1.4 0.33 0.223 0.139 0.8574 1.39 0.898 2.15 0.000134 0.231 1 0.0002009 1 0.636 1.57 PRS_PLINK_2.51188643150958e.06 FALSE 364.51 Fuchs' dystrophy Both 98 441 7 sense organs darkseagreen4 441, 98 111, 30 110, 20 110, 27 110, 21 -0.0107 0.125 0.931 0.03082 0.989 0.774 1.26 -0.357 0.319 0.263 0.5803 0.7 0.374 1.31 -0.131 0.3 0.663 0.1784 0.878 0.488 1.58 -0.335 0.316 0.288 0.5404 0.715 0.385 1.33 PRS_PLINK_2.51188643150958e.06 FALSE 364.9 Cornea replaced by transplant Both 27 141 7 sense organs darkseagreen4 141, 27 36, 5 35, 8 35, 4 35, 10 -0.0348 0.217 0.873 0.05917 0.966 0.631 1.48 0.945 0.701 0.177 0.7509 2.57 0.652 10.2 -0.146 0.706 0.836 0.0776 0.864 0.216 3.45 0.972 0.67 0.147 0.8327 2.64 0.711 9.82 PRS_PLINK_2.51188643150958e.06 TRUE 365 Glaucoma Both 818 3104 7 sense organs darkseagreen4 3104, 818 776, 201 776, 198 776, 223 776, 196 0.00192 0.0397 0.962 0.01705 1 0.927 1.08 -0.0202 0.114 0.86 0.06572 0.98 0.784 1.23 0.128 0.112 0.253 0.5967 1.14 0.913 1.41 -0.00282 0.114 0.98 0.008631 0.997 0.797 1.25 PRS_PLINK_2.51188643150958e.06 FALSE 365.1 Open-angle glaucoma Both 242 1036 7 sense organs darkseagreen4 1036, 242 259, 65 259, 60 259, 65 259, 52 -0.0522 0.0685 0.446 0.3507 0.949 0.83 1.09 -0.0653 0.203 0.747 0.1265 0.937 0.63 1.39 0.0216 0.198 0.913 0.03958 1.02 0.693 1.51 -0.202 0.21 0.335 0.4744 0.817 0.541 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 365.11 Primary open angle glaucoma Both 141 590 7 sense organs darkseagreen4 590, 141 148, 44 147, 34 147, 33 148, 30 -0.0235 0.0978 0.81 0.09164 0.977 0.806 1.18 -0.155 0.264 0.557 0.2545 0.856 0.511 1.44 -0.269 0.263 0.306 0.5137 0.764 0.456 1.28 -0.358 0.273 0.19 0.7223 0.699 0.41 1.19 PRS_PLINK_2.51188643150958e.06 FALSE 365.2 Primary angle-closure glaucoma Both 91 395 7 sense organs darkseagreen4 395, 91 99, 21 99, 25 98, 28 99, 17 -0.084 0.13 0.518 0.2859 0.919 0.713 1.19 0.234 0.334 0.483 0.3161 1.26 0.657 2.43 0.375 0.333 0.26 0.5854 1.45 0.758 2.79 -0.128 0.356 0.719 0.1433 0.88 0.438 1.77 PRS_PLINK_2.51188643150958e.06 FALSE 366 Cataract Both 2930 3445 7 sense organs darkseagreen4 3445, 2930 862, 772 861, 738 861, 710 861, 709 0.00714 0.0284 0.802 0.09604 1.01 0.953 1.06 -0.0271 0.0791 0.732 0.1353 0.973 0.833 1.14 -0.0442 0.0804 0.582 0.2347 0.957 0.817 1.12 -0.0348 0.0793 0.66 0.1801 0.966 0.827 1.13 PRS_PLINK_2.51188643150958e.06 FALSE 366.1 Nonsenile Cataract Both 89 270 7 sense organs darkseagreen4 270, 89 68, 24 67, 25 67, 18 68, 22 -0.0512 0.117 0.661 0.1801 0.95 0.756 1.19 -0.0214 0.345 0.95 0.02207 0.979 0.498 1.92 -0.254 0.371 0.495 0.3057 0.776 0.375 1.61 0.0565 0.361 0.876 0.05766 1.06 0.521 2.15 PRS_PLINK_2.51188643150958e.06 FALSE 366.2 Senile cataract Both 2160 3024 7 sense organs darkseagreen4 3024, 2160 756, 585 756, 542 756, 506 756, 526 0.0119 0.031 0.7 0.1547 1.01 0.952 1.08 -0.0634 0.0865 0.464 0.3338 0.939 0.792 1.11 -0.0952 0.0876 0.277 0.5571 0.909 0.766 1.08 -0.0564 0.086 0.512 0.2911 0.945 0.799 1.12 PRS_PLINK_2.51188643150958e.06 FALSE 367 Disorders of refraction and accommodation; blindness and low vision Both 3056 4395 7 sense organs darkseagreen4 4395, 3056 1099, 738 1099, 807 1098, 750 1099, 760 0.0197 0.0243 0.418 0.3787 1.02 0.972 1.07 0.086 0.0681 0.207 0.6847 1.09 0.954 1.25 0.0355 0.069 0.607 0.2166 1.04 0.905 1.19 0.0524 0.069 0.448 0.3491 1.05 0.921 1.21 PRS_PLINK_2.51188643150958e.06 FALSE 367.1 Myopia Both 1674 4117 7 sense organs darkseagreen4 4117, 1674 1030, 402 1029, 458 1029, 393 1029, 420 0.0154 0.0294 0.6 0.2218 1.02 0.959 1.08 0.13 0.0825 0.114 0.9434 1.14 0.969 1.34 -0.000352 0.0848 0.997 0.00144 1 0.846 1.18 0.0698 0.0841 0.406 0.3914 1.07 0.909 1.26 PRS_PLINK_2.51188643150958e.06 FALSE 367.2 Astigmatism Both 1405 3945 7 sense organs darkseagreen4 3945, 1405 987, 333 986, 382 986, 339 986, 350 0.0153 0.0317 0.629 0.2016 1.02 0.954 1.08 0.146 0.0887 0.1 1 1.16 0.972 1.38 0.0315 0.0908 0.729 0.1375 1.03 0.864 1.23 0.0549 0.0905 0.544 0.2644 1.06 0.885 1.26 PRS_PLINK_2.51188643150958e.06 FALSE 367.8 Hypermetropia Both 756 2414 7 sense organs darkseagreen4 2414, 756 604, 198 603, 193 603, 191 604, 174 -0.0139 0.0418 0.74 0.1307 0.986 0.909 1.07 -0.00153 0.117 0.99 0.004541 0.998 0.793 1.26 -0.00503 0.117 0.966 0.01511 0.995 0.79 1.25 -0.106 0.12 0.377 0.4233 0.9 0.712 1.14 PRS_PLINK_2.51188643150958e.06 FALSE 367.9 Blindness and low vision Both 455 1606 7 sense organs darkseagreen4 1606, 455 402, 124 401, 104 401, 109 402, 118 -0.0405 0.0528 0.443 0.3534 0.96 0.866 1.07 -0.187 0.152 0.219 0.66 0.829 0.615 1.12 -0.127 0.151 0.401 0.3972 0.881 0.655 1.18 -0.0379 0.148 0.798 0.09804 0.963 0.72 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 368 Visual disturbances Both 2078 5230 7 sense organs darkseagreen4 5230, 2078 1308, 541 1307, 528 1307, 486 1308, 522 -0.0303 0.0261 0.245 0.6103 0.97 0.922 1.02 -0.0373 0.0736 0.612 0.2131 0.963 0.834 1.11 -0.113 0.075 0.131 0.8815 0.893 0.771 1.03 -0.0196 0.0738 0.791 0.102 0.981 0.849 1.13 PRS_PLINK_2.51188643150958e.06 FALSE 368.1 Amblyopia Both 210 921 7 sense organs darkseagreen4 921, 210 231, 62 230, 54 230, 43 230, 51 -0.138 0.0762 0.0712 1.147 0.872 0.751 1.01 -0.106 0.208 0.609 0.2154 0.899 0.599 1.35 -0.341 0.219 0.119 0.9236 0.711 0.463 1.09 -0.19 0.213 0.372 0.4299 0.827 0.545 1.26 PRS_PLINK_2.51188643150958e.06 FALSE 368.2 Diplopia and disorders of binocular vision Both 404 1588 7 sense organs darkseagreen4 1588, 404 397, 114 397, 96 397, 94 397, 100 -0.108 0.0517 0.0376 1.424 0.898 0.811 0.994 -0.177 0.157 0.258 0.5878 0.837 0.616 1.14 -0.179 0.157 0.253 0.5969 0.836 0.615 1.14 -0.111 0.156 0.478 0.3208 0.895 0.659 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 368.3 Anisometropia Both 84 306 7 sense organs darkseagreen4 306, 84 77, 17 76, 32 76, 17 77, 18 -0.122 0.109 0.263 0.5795 0.885 0.715 1.1 0.669 0.348 0.0544 1.264 1.95 0.987 3.86 0.00927 0.393 0.981 0.00826 1.01 0.468 2.18 0.0995 0.375 0.791 0.1019 1.1 0.529 2.3 PRS_PLINK_2.51188643150958e.06 FALSE 368.4 Visual field defects Both 399 1663 7 sense organs darkseagreen4 1663, 399 416, 100 416, 105 415, 105 416, 89 -0.0395 0.0553 0.475 0.323 0.961 0.862 1.07 0.0332 0.157 0.833 0.07957 1.03 0.76 1.41 0.0434 0.156 0.781 0.1073 1.04 0.769 1.42 -0.137 0.163 0.401 0.3964 0.872 0.634 1.2 PRS_PLINK_2.51188643150958e.06 FALSE 368.9 Subjective visual disturbances Both 484 1615 7 sense organs darkseagreen4 1615, 484 404, 124 404, 126 403, 109 404, 125 -0.00655 0.0521 0.9 0.04579 0.993 0.897 1.1 0.00683 0.146 0.963 0.01657 1.01 0.757 1.34 -0.126 0.15 0.401 0.3965 0.882 0.657 1.18 0.0163 0.146 0.911 0.04057 1.02 0.764 1.35 PRS_PLINK_2.51188643150958e.06 FALSE 368.91 Psychophysical visual disturbances Both 73 159 7 sense organs darkseagreen4 159, 73 40, 22 40, 15 39, 23 40, 13 -0.0739 0.174 0.672 0.1728 0.929 0.66 1.31 -0.558 0.434 0.199 0.7018 0.573 0.245 1.34 -0.0846 0.402 0.833 0.07912 0.919 0.417 2.02 -0.603 0.447 0.177 0.751 0.547 0.228 1.31 PRS_PLINK_2.51188643150958e.06 FALSE 369 Infection of the eye Both 1054 3660 7 sense organs darkseagreen4 3660, 1054 915, 243 915, 281 915, 259 915, 271 0.0452 0.0366 0.217 0.664 1.05 0.974 1.12 0.123 0.1 0.219 0.6595 1.13 0.929 1.38 0.057 0.102 0.576 0.2396 1.06 0.867 1.29 0.117 0.101 0.245 0.6114 1.12 0.923 1.37 PRS_PLINK_2.51188643150958e.06 FALSE 369.2 Eye infection, viral Both 170 730 7 sense organs darkseagreen4 730, 170 183, 43 182, 43 182, 47 183, 37 -0.0133 0.0904 0.883 0.05393 0.987 0.827 1.18 -0.00623 0.242 0.979 0.009002 0.994 0.618 1.6 0.0593 0.24 0.805 0.09431 1.06 0.663 1.7 -0.124 0.248 0.617 0.21 0.883 0.543 1.44 PRS_PLINK_2.51188643150958e.06 FALSE 369.5 Conjunctivitis, infectious Both 915 3315 7 sense organs darkseagreen4 3315, 915 829, 209 829, 247 828, 217 829, 242 0.0588 0.0391 0.133 0.8761 1.06 0.982 1.15 0.142 0.107 0.182 0.7395 1.15 0.935 1.42 0.0349 0.11 0.75 0.1247 1.04 0.835 1.28 0.149 0.107 0.166 0.7801 1.16 0.94 1.43 PRS_PLINK_2.51188643150958e.06 FALSE 370 Keratitis Both 510 1931 7 sense organs darkseagreen4 1931, 510 483, 131 483, 128 482, 129 483, 122 -0.018 0.0507 0.723 0.1409 0.982 0.889 1.08 -0.0203 0.142 0.886 0.05256 0.98 0.742 1.29 -0.0237 0.142 0.867 0.06192 0.977 0.74 1.29 -0.0762 0.143 0.595 0.2257 0.927 0.7 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 370.1 Corneal ulcer Both 61 316 7 sense organs darkseagreen4 316, 61 79, 17 79, 13 79, 20 79, 11 -0.0967 0.148 0.513 0.29 0.908 0.68 1.21 -0.447 0.404 0.268 0.5721 0.639 0.29 1.41 0.114 0.372 0.76 0.1191 1.12 0.54 2.32 -0.513 0.417 0.219 0.6597 0.599 0.264 1.36 PRS_PLINK_2.51188643150958e.06 FALSE 370.2 Superficial keratitis Both 223 805 7 sense organs darkseagreen4 805, 223 202, 58 201, 50 201, 54 201, 61 0.0393 0.0765 0.607 0.2165 1.04 0.895 1.21 -0.143 0.221 0.519 0.285 0.867 0.562 1.34 -0.0281 0.219 0.898 0.0469 0.972 0.633 1.49 0.0944 0.213 0.658 0.182 1.1 0.724 1.67 PRS_PLINK_2.51188643150958e.06 FALSE 370.3 Keratoconjunctivitis Both 262 971 7 sense organs darkseagreen4 971, 262 243, 59 243, 68 242, 65 243, 70 0.0338 0.0714 0.636 0.1965 1.03 0.899 1.19 0.118 0.202 0.56 0.2519 1.12 0.758 1.67 0.108 0.204 0.596 0.2251 1.11 0.747 1.66 0.2 0.201 0.32 0.4943 1.22 0.823 1.81 PRS_PLINK_2.51188643150958e.06 FALSE 370.31 Keratoconjunctivitis sicca Both 94 262 7 sense organs darkseagreen4 262, 94 66, 22 65, 24 65, 17 66, 31 0.0313 0.132 0.813 0.09007 1.03 0.796 1.34 0.177 0.356 0.618 0.2088 1.19 0.594 2.4 -0.263 0.379 0.488 0.3119 0.769 0.366 1.62 0.299 0.335 0.372 0.4297 1.35 0.699 2.6 PRS_PLINK_2.51188643150958e.06 FALSE 371 Inflammation of the eye Both 1612 4259 7 sense organs darkseagreen4 4259, 1612 1065, 396 1065, 439 1064, 376 1065, 400 -0.000872 0.0299 0.977 0.01024 0.999 0.942 1.06 0.1 0.0841 0.233 0.632 1.11 0.937 1.3 -0.0373 0.0864 0.666 0.1763 0.963 0.813 1.14 0.0341 0.0847 0.687 0.163 1.03 0.876 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 371.1 Uveitis, noninfectious or NOS Both 200 789 7 sense organs darkseagreen4 789, 200 198, 55 197, 43 197, 48 197, 54 -0.0412 0.0732 0.573 0.2417 0.96 0.831 1.11 -0.254 0.228 0.265 0.577 0.775 0.496 1.21 -0.117 0.224 0.601 0.2209 0.89 0.574 1.38 0.0442 0.221 0.841 0.07507 1.05 0.678 1.61 PRS_PLINK_2.51188643150958e.06 FALSE 371.2 Conjunctivitis, noninfectious Both 319 1315 7 sense organs darkseagreen4 1315, 319 329, 70 329, 78 328, 79 329, 92 0.113 0.0656 0.0846 1.072 1.12 0.985 1.27 0.125 0.184 0.497 0.3033 1.13 0.79 1.62 0.126 0.185 0.495 0.3057 1.13 0.79 1.63 0.325 0.18 0.0706 1.151 1.38 0.973 1.97 PRS_PLINK_2.51188643150958e.06 FALSE 371.21 Allergic conjunctivitis Both 260 1116 7 sense organs darkseagreen4 1116, 260 279, 55 279, 65 279, 65 279, 75 0.147 0.0753 0.0505 1.297 1.16 1 1.34 0.162 0.203 0.427 0.3695 1.18 0.789 1.75 0.173 0.205 0.398 0.4005 1.19 0.796 1.78 0.373 0.201 0.064 1.194 1.45 0.979 2.15 PRS_PLINK_2.51188643150958e.06 FALSE 371.3 Inflammation of eyelids Both 1282 3655 7 sense organs darkseagreen4 3655, 1282 914, 318 914, 358 913, 303 914, 302 -0.00835 0.0328 0.799 0.09754 0.992 0.93 1.06 0.138 0.0925 0.136 0.8657 1.15 0.957 1.38 -0.0228 0.0952 0.811 0.09095 0.977 0.811 1.18 -0.0233 0.0948 0.806 0.0937 0.977 0.811 1.18 PRS_PLINK_2.51188643150958e.06 FALSE 371.33 Noninfectious dermatoses of eyelid Both 42 170 7 sense organs darkseagreen4 170, 42 43, 14 42, 14 42, 5 43, 9 -0.158 0.176 0.369 0.4325 0.854 0.604 1.21 0.206 0.46 0.653 0.185 1.23 0.5 3.03 -1.24 0.576 0.0314 1.502 0.289 0.0935 0.896 -0.387 0.503 0.441 0.3555 0.679 0.253 1.82 PRS_PLINK_2.51188643150958e.06 TRUE 372 Disorders of conjunctiva Both 388 1539 7 sense organs darkseagreen4 1539, 388 385, 111 385, 87 384, 96 385, 94 -0.0404 0.0571 0.479 0.3195 0.96 0.859 1.07 -0.262 0.162 0.106 0.9742 0.77 0.56 1.06 -0.138 0.159 0.385 0.4144 0.871 0.638 1.19 -0.182 0.161 0.258 0.588 0.834 0.609 1.14 PRS_PLINK_2.51188643150958e.06 FALSE 374 Other disorders of eyelids Both 1012 3304 7 sense organs darkseagreen4 3304, 1012 826, 260 826, 261 826, 234 826, 257 -0.00448 0.0367 0.903 0.04435 0.996 0.926 1.07 0.022 0.102 0.83 0.08104 1.02 0.837 1.25 -0.0739 0.105 0.48 0.3189 0.929 0.757 1.14 0.0202 0.103 0.844 0.07349 1.02 0.834 1.25 PRS_PLINK_2.51188643150958e.06 FALSE 374.1 Ectropion or entropion Both 116 582 7 sense organs darkseagreen4 582, 116 146, 30 145, 29 145, 28 146, 29 -0.017 0.0976 0.862 0.06472 0.983 0.812 1.19 -0.0178 0.286 0.95 0.02211 0.982 0.561 1.72 -0.00678 0.288 0.981 0.008219 0.993 0.564 1.75 0.0102 0.289 0.972 0.01241 1.01 0.574 1.78 PRS_PLINK_2.51188643150958e.06 FALSE 374.2 Lagophthalmos Both 59 320 7 sense organs darkseagreen4 320, 59 80, 15 80, 14 80, 16 80, 14 -0.035 0.136 0.796 0.0991 0.966 0.74 1.26 -0.189 0.413 0.648 0.1884 0.828 0.369 1.86 0.133 0.393 0.735 0.1339 1.14 0.529 2.47 0.101 0.414 0.807 0.09315 1.11 0.492 2.49 PRS_PLINK_2.51188643150958e.06 FALSE 374.3 Ptosis of eyelid Both 385 1547 7 sense organs darkseagreen4 1547, 385 387, 120 387, 96 386, 87 387, 82 -0.133 0.0536 0.0129 1.888 0.875 0.788 0.972 -0.243 0.156 0.119 0.9243 0.785 0.578 1.06 -0.319 0.159 0.0455 1.342 0.727 0.532 0.994 -0.345 0.162 0.0332 1.479 0.708 0.515 0.973 PRS_PLINK_2.51188643150958e.06 FALSE 374.6 Dermatochalasis Both 417 1466 7 sense organs darkseagreen4 1466, 417 367, 110 366, 104 366, 107 367, 96 -0.037 0.0571 0.517 0.2867 0.964 0.862 1.08 -0.0439 0.158 0.781 0.1075 0.957 0.703 1.3 -0.0422 0.157 0.788 0.1036 0.959 0.705 1.3 -0.111 0.16 0.49 0.3099 0.895 0.654 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 375 Disorders of lacrimal system Both 1464 3351 7 sense organs darkseagreen4 3351, 1464 838, 344 838, 398 837, 370 838, 351 0.0411 0.033 0.214 0.6698 1.04 0.977 1.11 0.134 0.092 0.145 0.8396 1.14 0.955 1.37 0.0981 0.0926 0.289 0.5386 1.1 0.92 1.32 0.0191 0.0931 0.838 0.07687 1.02 0.849 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 375.1 Dry eyes Both 1645 3448 7 sense organs darkseagreen4 3448, 1645 862, 384 862, 436 862, 424 862, 400 0.0487 0.0318 0.125 0.9032 1.05 0.987 1.12 0.106 0.0888 0.231 0.6372 1.11 0.935 1.32 0.118 0.0888 0.185 0.7334 1.12 0.945 1.34 0.0424 0.0892 0.634 0.1978 1.04 0.876 1.24 PRS_PLINK_2.51188643150958e.06 FALSE 375.2 Epiphora Both 136 539 7 sense organs darkseagreen4 539, 136 135, 32 135, 36 134, 40 135, 28 -0.0806 0.0923 0.383 0.4173 0.923 0.77 1.11 0.12 0.271 0.658 0.1817 1.13 0.663 1.92 0.222 0.27 0.411 0.3863 1.25 0.735 2.12 -0.076 0.287 0.791 0.1018 0.927 0.528 1.63 PRS_PLINK_2.51188643150958e.06 FALSE 376 Disorders of the orbit Both 69 426 7 sense organs darkseagreen4 426, 69 107, 18 106, 18 106, 13 107, 20 0.0103 0.125 0.935 0.02937 1.01 0.79 1.29 -0.0144 0.368 0.969 0.01376 0.986 0.479 2.03 -0.364 0.393 0.355 0.4503 0.695 0.322 1.5 0.0737 0.365 0.84 0.07586 1.08 0.527 2.2 PRS_PLINK_2.51188643150958e.06 FALSE 377 Disorders of optic nerve and visual pathways Both 298 1144 7 sense organs darkseagreen4 1144, 298 286, 83 286, 71 286, 84 286, 60 -0.0905 0.0608 0.136 0.8654 0.913 0.811 1.03 -0.167 0.185 0.366 0.4367 0.846 0.589 1.22 0.0137 0.177 0.938 0.02779 1.01 0.717 1.43 -0.322 0.192 0.0934 1.029 0.724 0.497 1.06 PRS_PLINK_2.51188643150958e.06 FALSE 377.1 Optic atrophy Both 116 380 7 sense organs darkseagreen4 380, 116 95, 34 95, 28 95, 28 95, 26 -0.0958 0.103 0.352 0.4531 0.909 0.743 1.11 -0.06 0.316 0.849 0.07094 0.942 0.507 1.75 -0.182 0.304 0.549 0.2606 0.833 0.459 1.51 -0.219 0.309 0.478 0.3209 0.803 0.439 1.47 PRS_PLINK_2.51188643150958e.06 FALSE 377.3 Optic neuritis/neuropathy Both 181 714 7 sense organs darkseagreen4 714, 181 179, 52 178, 42 178, 48 179, 39 -0.0793 0.0756 0.294 0.5317 0.924 0.796 1.07 -0.232 0.235 0.325 0.4887 0.793 0.5 1.26 -0.0294 0.23 0.898 0.04671 0.971 0.619 1.52 -0.245 0.24 0.308 0.5112 0.783 0.489 1.25 PRS_PLINK_2.51188643150958e.06 FALSE 378 Strabismus and other disorders of binocular eye movements Both 405 1595 7 sense organs darkseagreen4 1595, 405 399, 107 399, 99 398, 97 399, 102 -0.0473 0.053 0.372 0.4292 0.954 0.86 1.06 -0.0556 0.158 0.725 0.1398 0.946 0.694 1.29 -0.0641 0.16 0.689 0.1619 0.938 0.685 1.28 -0.0441 0.158 0.78 0.1078 0.957 0.702 1.3 PRS_PLINK_2.51188643150958e.06 FALSE 378.1 Strabismus (not specified as paralytic) Both 268 1077 7 sense organs darkseagreen4 1077, 268 270, 73 269, 72 269, 57 269, 66 -0.0964 0.0622 0.121 0.9174 0.908 0.804 1.03 0.018 0.189 0.924 0.03412 1.02 0.702 1.48 -0.241 0.201 0.231 0.636 0.786 0.529 1.17 -0.121 0.195 0.535 0.2716 0.886 0.605 1.3 PRS_PLINK_2.51188643150958e.06 FALSE 378.2 Nystagmus and other irregular eye movements Both 51 218 7 sense organs darkseagreen4 218, 51 55, 15 54, 7 54, 12 55, 17 0.145 0.156 0.353 0.4522 1.16 0.852 1.57 -0.689 0.502 0.17 0.7693 0.502 0.188 1.34 -0.0388 0.461 0.933 0.03021 0.962 0.39 2.37 0.102 0.416 0.806 0.09343 1.11 0.49 2.5 PRS_PLINK_2.51188643150958e.06 FALSE 378.5 Paralytic strabismus Both 98 435 7 sense organs darkseagreen4 435, 98 109, 31 109, 22 108, 18 109, 27 -0.0948 0.104 0.363 0.4401 0.91 0.741 1.12 -0.339 0.315 0.282 0.5498 0.712 0.384 1.32 -0.59 0.333 0.0767 1.115 0.554 0.288 1.07 -0.158 0.307 0.606 0.2174 0.854 0.468 1.56 PRS_PLINK_2.51188643150958e.06 FALSE 379 Other disorders of eye Both 1850 3744 7 sense organs darkseagreen4 3744, 1850 936, 471 936, 468 936, 461 936, 449 0.0214 0.0298 0.473 0.3252 1.02 0.964 1.08 -0.0105 0.0843 0.901 0.04549 0.99 0.839 1.17 0.0101 0.0841 0.905 0.04355 1.01 0.857 1.19 -0.031 0.0839 0.711 0.148 0.969 0.822 1.14 PRS_PLINK_2.51188643150958e.06 FALSE 379.1 Scleritis and episcleritis Both 75 242 7 sense organs darkseagreen4 242, 75 61, 22 60, 17 60, 11 61, 25 0.0672 0.121 0.578 0.2377 1.07 0.844 1.36 -0.25 0.375 0.506 0.296 0.779 0.373 1.63 -0.658 0.414 0.112 0.9499 0.518 0.23 1.17 0.143 0.352 0.685 0.1646 1.15 0.578 2.3 PRS_PLINK_2.51188643150958e.06 FALSE 379.2 Disorders of vitreous body Both 1377 2930 7 sense organs darkseagreen4 2930, 1377 733, 369 732, 356 732, 338 733, 313 -0.0115 0.0338 0.734 0.1344 0.989 0.925 1.06 -0.000803 0.0954 0.993 0.002924 0.999 0.829 1.2 -0.0254 0.0962 0.792 0.1014 0.975 0.807 1.18 -0.11 0.0964 0.253 0.5976 0.896 0.741 1.08 PRS_PLINK_2.51188643150958e.06 FALSE 379.3 Aphakia and other disorders of lens Both 50 175 7 sense organs darkseagreen4 175, 50 44, 17 44, 9 43, 10 44, 14 -0.103 0.149 0.49 0.3098 0.902 0.674 1.21 -0.484 0.52 0.353 0.4525 0.617 0.222 1.71 -0.404 0.486 0.405 0.3921 0.667 0.257 1.73 -0.266 0.457 0.561 0.2508 0.767 0.313 1.88 PRS_PLINK_2.51188643150958e.06 TRUE 379.4 Anomalies of pupillary function Both 105 409 7 sense organs darkseagreen4 409, 105 103, 30 102, 22 102, 35 102, 18 -0.0717 0.113 0.526 0.2786 0.931 0.746 1.16 -0.264 0.317 0.405 0.3924 0.768 0.412 1.43 0.206 0.29 0.476 0.3225 1.23 0.697 2.17 -0.52 0.343 0.129 0.8892 0.595 0.304 1.16 PRS_PLINK_2.51188643150958e.06 FALSE 379.5 Disorders of iris and ciliary body Both 109 418 7 sense organs darkseagreen4 418, 109 105, 32 104, 23 104, 34 105, 20 -0.0901 0.106 0.394 0.4045 0.914 0.743 1.12 -0.312 0.316 0.323 0.4902 0.732 0.394 1.36 0.0658 0.288 0.819 0.08647 1.07 0.607 1.88 -0.441 0.317 0.164 0.7854 0.643 0.346 1.2 PRS_PLINK_2.51188643150958e.06 FALSE 379.51 Pigmentary iris degeneration Both 20 80 7 sense organs darkseagreen4 80, 20 20, 6 20, 6 20, 3 20, 5 0.0288 0.293 0.922 0.03545 1.03 0.58 1.83 0.433 0.781 0.579 0.2372 1.54 0.334 7.13 -0.659 0.89 0.459 0.3382 0.517 0.0904 2.96 0.342 0.748 0.648 0.1887 1.41 0.325 6.1 PRS_PLINK_2.51188643150958e.06 TRUE 379.9 Pain, swelling or discharge of eye Both 439 1497 7 sense organs darkseagreen4 1497, 439 375, 110 374, 109 374, 118 374, 102 -0.00747 0.0522 0.886 0.05252 0.993 0.896 1.1 0.00984 0.155 0.949 0.02263 1.01 0.746 1.37 0.105 0.154 0.495 0.3057 1.11 0.822 1.5 -0.0118 0.158 0.94 0.0267 0.988 0.725 1.35 PRS_PLINK_2.51188643150958e.06 FALSE 380 Disorders of external ear Both 894 3156 7 sense organs darkseagreen4 3156, 894 788, 210 789, 239 789, 205 789, 240 0.0419 0.0387 0.278 0.5555 1.04 0.967 1.12 0.143 0.109 0.189 0.7245 1.15 0.932 1.43 -0.0168 0.112 0.881 0.05519 0.983 0.789 1.22 0.157 0.109 0.149 0.8281 1.17 0.946 1.45 PRS_PLINK_2.51188643150958e.06 FALSE 380.1 Otitis externa Both 560 2241 7 sense organs darkseagreen4 2241, 560 560, 149 560, 136 560, 122 560, 153 0.000745 0.0475 0.987 0.005474 1 0.912 1.1 -0.0894 0.134 0.506 0.2958 0.915 0.703 1.19 -0.206 0.137 0.132 0.8786 0.814 0.622 1.06 0.0211 0.132 0.872 0.05928 1.02 0.789 1.32 PRS_PLINK_2.51188643150958e.06 FALSE 380.4 Impacted cerumen Both 1057 3578 7 sense organs darkseagreen4 3578, 1057 894, 247 894, 268 894, 247 895, 295 0.0542 0.0361 0.133 0.8755 1.06 0.984 1.13 0.0966 0.102 0.343 0.465 1.1 0.902 1.34 0.0209 0.103 0.84 0.07585 1.02 0.834 1.25 0.191 0.0999 0.0555 1.256 1.21 0.996 1.47 PRS_PLINK_2.51188643150958e.06 FALSE 381 Otitis media and Eustachian tube disorders Both 1276 5120 7 sense organs darkseagreen4 5120, 1276 1280, 289 1280, 350 1280, 307 1280, 330 0.0293 0.0319 0.358 0.4458 1.03 0.967 1.1 0.195 0.0893 0.0286 1.543 1.22 1.02 1.45 0.0647 0.0913 0.478 0.3203 1.07 0.892 1.28 0.139 0.0902 0.124 0.9082 1.15 0.963 1.37 PRS_PLINK_2.51188643150958e.06 FALSE 381.1 Otitis media Both 901 4136 7 sense organs darkseagreen4 4136, 901 1034, 201 1034, 243 1034, 213 1034, 244 0.0541 0.0378 0.153 0.8156 1.06 0.98 1.14 0.19 0.106 0.0718 1.144 1.21 0.983 1.49 0.0584 0.108 0.589 0.2301 1.06 0.858 1.31 0.197 0.106 0.0614 1.212 1.22 0.991 1.5 PRS_PLINK_2.51188643150958e.06 FALSE 381.11 Suppurative and unspecified otitis media Both 764 3539 7 sense organs darkseagreen4 3539, 764 885, 170 885, 192 884, 195 885, 207 0.0674 0.0414 0.103 0.9858 1.07 0.986 1.16 0.122 0.117 0.297 0.5278 1.13 0.899 1.42 0.128 0.116 0.268 0.5715 1.14 0.906 1.43 0.196 0.115 0.0869 1.061 1.22 0.972 1.52 PRS_PLINK_2.51188643150958e.06 FALSE 381.2 Eustachian tube disorders Both 608 2596 7 sense organs darkseagreen4 2596, 608 649, 135 649, 170 649, 152 649, 151 0.0415 0.0462 0.37 0.4317 1.04 0.952 1.14 0.235 0.129 0.0678 1.169 1.26 0.983 1.63 0.121 0.132 0.356 0.449 1.13 0.873 1.46 0.117 0.132 0.373 0.428 1.12 0.868 1.46 PRS_PLINK_2.51188643150958e.06 FALSE 381.3 Mastoiditis & related conditions Both 30 222 7 sense organs darkseagreen4 222, 30 56, 5 55, 5 55, 8 56, 12 0.382 0.234 0.103 0.9858 1.46 0.925 2.32 0.261 0.66 0.692 0.1598 1.3 0.356 4.73 0.544 0.586 0.353 0.452 1.72 0.546 5.43 0.678 0.547 0.216 0.6661 1.97 0.674 5.76 PRS_PLINK_2.51188643150958e.06 TRUE 381.9 Otorrhea Both 92 519 7 sense organs darkseagreen4 519, 92 130, 23 130, 21 129, 22 130, 26 -0.025 0.0963 0.795 0.09968 0.975 0.808 1.18 -0.0876 0.323 0.786 0.1045 0.916 0.486 1.73 -0.0861 0.323 0.79 0.1024 0.917 0.487 1.73 0.0876 0.312 0.779 0.1087 1.09 0.593 2.01 PRS_PLINK_2.51188643150958e.06 FALSE 382 Otalgia Both 694 2738 7 sense organs darkseagreen4 2738, 694 685, 157 684, 181 684, 163 685, 193 0.0386 0.0428 0.367 0.4358 1.04 0.956 1.13 0.143 0.123 0.243 0.6152 1.15 0.907 1.47 0.0207 0.125 0.868 0.06128 1.02 0.799 1.3 0.224 0.122 0.0667 1.176 1.25 0.985 1.59 PRS_PLINK_2.51188643150958e.06 FALSE 383 Otosclerosis Both 22 188 7 sense organs darkseagreen4 188, 22 47, 6 47, 7 47, 5 47, 4 -0.17 0.188 0.366 0.4365 0.844 0.584 1.22 0.0451 0.594 0.94 0.02706 1.05 0.326 3.35 0.00705 0.695 0.992 0.003529 1.01 0.258 3.93 0.102 0.697 0.883 0.05393 1.11 0.283 4.34 PRS_PLINK_2.51188643150958e.06 TRUE 384 Other disorders of tympanic membrane Both 129 656 7 sense organs darkseagreen4 656, 129 164, 32 164, 39 164, 27 164, 31 0.00905 0.0987 0.927 0.03293 1.01 0.832 1.22 0.201 0.266 0.451 0.3461 1.22 0.725 2.06 -0.13 0.284 0.646 0.1896 0.878 0.503 1.53 -0.0247 0.276 0.929 0.03207 0.976 0.568 1.68 PRS_PLINK_2.51188643150958e.06 FALSE 384.1 Myringitis Both 14 71 7 sense organs darkseagreen4 71, 14 18, 2 18, 4 17, 5 18, 3 0.21 0.313 0.503 0.2981 1.23 0.667 2.28 0.74 0.922 0.422 0.3746 2.1 0.344 12.8 0.176 0.93 0.85 0.07082 1.19 0.193 7.38 -0.497 1.01 0.624 0.205 0.608 0.0834 4.44 PRS_PLINK_2.51188643150958e.06 TRUE 384.4 Perforation of tympanic membrane Both 94 519 7 sense organs darkseagreen4 519, 94 130, 25 130, 27 129, 21 130, 21 0.0308 0.112 0.782 0.1066 1.03 0.829 1.28 0.107 0.305 0.727 0.1387 1.11 0.612 2.02 -0.139 0.325 0.668 0.1752 0.87 0.46 1.64 -0.09 0.32 0.779 0.1087 0.914 0.488 1.71 PRS_PLINK_2.51188643150958e.06 FALSE 385 Other disorders of middle ear and mastoid Both 64 561 7 sense organs darkseagreen4 561, 64 141, 11 140, 15 140, 17 140, 21 0.127 0.144 0.378 0.4222 1.13 0.856 1.5 0.362 0.422 0.39 0.4089 1.44 0.629 3.28 0.49 0.409 0.23 0.6383 1.63 0.733 3.64 0.661 0.401 0.0994 1.003 1.94 0.882 4.25 PRS_PLINK_2.51188643150958e.06 FALSE 385.3 Cholesteatoma Both 24 346 7 sense organs darkseagreen4 346, 24 87, 4 86, 5 86, 6 87, 9 0.0465 0.194 0.811 0.09103 1.05 0.716 1.53 0.229 0.617 0.71 0.1486 1.26 0.375 4.22 0.293 0.62 0.637 0.1961 1.34 0.398 4.52 0.841 0.604 0.164 0.7853 2.32 0.71 7.58 PRS_PLINK_2.51188643150958e.06 TRUE 385.5 Tympanosclerosis and middle ear disease related to otitis media Both 14 165 7 sense organs darkseagreen4 165, 14 42, 1 41, 3 41, 5 41, 5 0.445 0.343 0.194 0.7121 1.56 0.797 3.06 0.904 0.869 0.299 0.5248 2.47 0.449 13.6 1.65 0.899 0.0663 1.179 5.21 0.895 30.3 1.45 1.19 0.226 0.6457 4.24 0.409 44 PRS_PLINK_2.51188643150958e.06 TRUE 386 Vertiginous syndromes and other disorders of vestibular system Both 693 2465 7 sense organs darkseagreen4 2465, 693 617, 198 616, 166 616, 176 616, 152 -0.0437 0.0421 0.299 0.5246 0.957 0.881 1.04 -0.2 0.121 0.0966 1.015 0.818 0.646 1.04 -0.107 0.12 0.372 0.4293 0.899 0.711 1.14 -0.282 0.124 0.0227 1.644 0.754 0.592 0.961 PRS_PLINK_2.51188643150958e.06 FALSE 386.1 Meniere's disease Both 94 444 7 sense organs darkseagreen4 444, 94 111, 24 111, 29 111, 25 111, 16 -0.129 0.118 0.275 0.5612 0.879 0.698 1.11 0.149 0.311 0.632 0.1992 1.16 0.63 2.14 -0.0433 0.319 0.892 0.0497 0.958 0.513 1.79 -0.484 0.35 0.167 0.7785 0.616 0.31 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 386.2 Peripheral or central vertigo Both 611 2112 7 sense organs darkseagreen4 2112, 611 528, 176 528, 147 528, 154 528, 133 -0.0497 0.0449 0.269 0.5706 0.952 0.871 1.04 -0.195 0.128 0.128 0.8939 0.823 0.64 1.06 -0.119 0.128 0.35 0.4556 0.888 0.691 1.14 -0.294 0.132 0.0262 1.581 0.745 0.575 0.966 PRS_PLINK_2.51188643150958e.06 FALSE 386.21 Central origin vertigo Both 450 1637 7 sense organs darkseagreen4 1637, 450 410, 123 409, 108 409, 119 409, 99 -0.0348 0.0532 0.513 0.2898 0.966 0.87 1.07 -0.163 0.15 0.277 0.5578 0.849 0.633 1.14 -0.0295 0.148 0.842 0.07446 0.971 0.726 1.3 -0.234 0.155 0.13 0.8847 0.792 0.585 1.07 PRS_PLINK_2.51188643150958e.06 FALSE 386.3 Labyrinthitis Both 527 1976 7 sense organs darkseagreen4 1976, 527 494, 149 494, 125 494, 138 494, 114 -0.0547 0.0484 0.259 0.5874 0.947 0.861 1.04 -0.204 0.138 0.139 0.8576 0.815 0.622 1.07 -0.0771 0.136 0.571 0.2433 0.926 0.709 1.21 -0.284 0.142 0.0455 1.342 0.753 0.57 0.994 PRS_PLINK_2.51188643150958e.06 FALSE 386.9 Dizziness and giddiness (Light-headedness and vertigo) Both 2616 4671 7 sense organs darkseagreen4 4671, 2616 1168, 652 1168, 669 1167, 662 1168, 632 0.0315 0.025 0.208 0.6818 1.03 0.983 1.08 0.0195 0.0701 0.781 0.1074 1.02 0.889 1.17 0.0219 0.0706 0.756 0.1216 1.02 0.89 1.17 -0.00951 0.0712 0.894 0.04882 0.991 0.862 1.14 PRS_PLINK_2.51188643150958e.06 FALSE 388 Other disorders of ear Both 315 1326 7 sense organs darkseagreen4 1326, 315 332, 69 331, 82 331, 87 332, 77 0.0727 0.0668 0.276 0.5584 1.08 0.943 1.23 0.212 0.184 0.249 0.6034 1.24 0.862 1.77 0.233 0.182 0.199 0.7007 1.26 0.884 1.8 0.0932 0.184 0.613 0.2128 1.1 0.765 1.57 PRS_PLINK_2.51188643150958e.06 FALSE 389 Hearing loss Both 2340 4995 7 sense organs darkseagreen4 4995, 2340 1249, 643 1249, 599 1248, 526 1249, 571 -0.0198 0.0261 0.447 0.3494 0.98 0.931 1.03 -0.0649 0.0728 0.373 0.4285 0.937 0.813 1.08 -0.203 0.0746 0.00664 2.178 0.817 0.706 0.945 -0.0895 0.0737 0.225 0.6487 0.914 0.791 1.06 PRS_PLINK_2.51188643150958e.06 FALSE 389.1 Sensorineural hearing loss Both 1353 4012 7 sense organs darkseagreen4 4012, 1353 1003, 371 1003, 351 1003, 298 1003, 333 -0.00821 0.0325 0.801 0.09652 0.992 0.931 1.06 -0.0214 0.0905 0.813 0.08983 0.979 0.82 1.17 -0.188 0.0935 0.0446 1.35 0.829 0.69 0.995 -0.0691 0.0918 0.451 0.3456 0.933 0.78 1.12 PRS_PLINK_2.51188643150958e.06 FALSE 389.2 Conductive hearing loss Both 209 1171 7 sense organs darkseagreen4 1171, 209 293, 56 293, 52 292, 49 293, 52 -0.0169 0.0745 0.821 0.0859 0.983 0.85 1.14 -0.117 0.212 0.58 0.2362 0.889 0.586 1.35 -0.109 0.216 0.613 0.2126 0.897 0.588 1.37 -0.0843 0.213 0.692 0.1598 0.919 0.606 1.39 PRS_PLINK_2.51188643150958e.06 FALSE 389.3 Degenerative and vascular disorders of ear Both 80 277 7 sense organs darkseagreen4 277, 80 70, 24 69, 25 69, 19 69, 12 -0.154 0.12 0.201 0.6976 0.857 0.677 1.09 0.0615 0.339 0.856 0.06758 1.06 0.548 2.07 -0.339 0.375 0.366 0.4364 0.713 0.342 1.49 -0.733 0.418 0.0795 1.1 0.481 0.212 1.09 PRS_PLINK_2.51188643150958e.06 FALSE 389.4 Tinnitus Both 728 3069 7 sense organs darkseagreen4 3069, 728 768, 198 767, 208 767, 152 767, 170 -0.0498 0.04 0.213 0.6724 0.951 0.88 1.03 0.0558 0.112 0.618 0.2089 1.06 0.849 1.32 -0.259 0.12 0.0304 1.517 0.772 0.611 0.976 -0.124 0.117 0.289 0.5385 0.883 0.702 1.11 PRS_PLINK_2.51188643150958e.06 FALSE 389.5 Disorders of acoustic nerve Both 51 145 7 sense organs darkseagreen4 145, 51 37, 11 36, 16 36, 8 36, 16 0.0531 0.154 0.73 0.1366 1.05 0.78 1.43 0.279 0.468 0.551 0.2589 1.32 0.528 3.31 -0.312 0.533 0.558 0.2535 0.732 0.258 2.08 0.437 0.468 0.351 0.4547 1.55 0.618 3.87 PRS_PLINK_2.51188643150958e.06 FALSE 394 Rheumatic disease of the heart valves Both 472 2147 8 circulatory system red 2147, 472 537, 123 537, 112 536, 118 537, 118 -0.0271 0.0509 0.594 0.2264 0.973 0.881 1.08 -0.0739 0.145 0.609 0.2152 0.929 0.699 1.23 -0.0263 0.143 0.854 0.0685 0.974 0.736 1.29 -0.0226 0.144 0.875 0.05787 0.978 0.737 1.3 PRS_PLINK_2.51188643150958e.06 FALSE 394.1 Mitral valve stenosis and aortic valve stenosis Both 137 546 8 circulatory system red 546, 137 137, 34 136, 40 136, 28 137, 35 -0.0144 0.0975 0.882 0.0544 0.986 0.814 1.19 0.285 0.269 0.289 0.5384 1.33 0.785 2.26 -0.154 0.282 0.585 0.2326 0.857 0.493 1.49 0.125 0.277 0.651 0.1867 1.13 0.659 1.95 PRS_PLINK_2.51188643150958e.06 FALSE 394.2 Mitral valve disease Both 158 714 8 circulatory system red 714, 158 179, 41 178, 33 178, 43 179, 40 -0.0603 0.0852 0.479 0.3192 0.941 0.797 1.11 -0.123 0.259 0.636 0.1968 0.884 0.532 1.47 0.0479 0.249 0.848 0.07178 1.05 0.644 1.71 0.000619 0.252 0.998 0.0008516 1 0.61 1.64 PRS_PLINK_2.51188643150958e.06 FALSE 394.3 Aortic valve disease Both 45 298 8 circulatory system red 298, 45 75, 11 74, 11 74, 11 75, 12 -0.0151 0.16 0.925 0.0339 0.985 0.72 1.35 0.0154 0.452 0.973 0.01195 1.02 0.419 2.46 -0.0519 0.443 0.907 0.04251 0.949 0.398 2.26 0.0853 0.471 0.856 0.06737 1.09 0.432 2.74 PRS_PLINK_2.51188643150958e.06 TRUE 394.4 Acute rheumatic heart disease Both 20 81 8 circulatory system red 81, 20 21, 5 20, 11 20, 0 20, 4 -0.367 0.309 0.235 0.6286 0.693 0.378 1.27 2.3 0.966 0.0175 1.757 9.93 1.49 66 -2.45 1.43 0.0862 1.064 0.0861 0.00523 1.42 0.491 0.839 0.558 0.2532 1.63 0.316 8.47 PRS_PLINK_2.51188643150958e.06 TRUE 394.7 Disease of tricuspid valve Both 193 846 8 circulatory system red 846, 193 212, 48 211, 40 211, 51 212, 54 0.0575 0.083 0.489 0.311 1.06 0.9 1.25 -0.167 0.236 0.479 0.3195 0.846 0.533 1.34 0.0628 0.225 0.78 0.108 1.06 0.685 1.65 0.118 0.225 0.601 0.221 1.12 0.724 1.75 PRS_PLINK_2.51188643150958e.06 FALSE 395 Heart valve disorders Both 1114 4300 8 circulatory system red 4300, 1114 1075, 285 1075, 263 1075, 293 1075, 272 -0.0323 0.0341 0.343 0.4646 0.968 0.906 1.04 -0.0733 0.0976 0.453 0.3442 0.929 0.768 1.13 0.0429 0.0967 0.658 0.182 1.04 0.864 1.26 -0.0362 0.097 0.709 0.1495 0.964 0.797 1.17 PRS_PLINK_2.51188643150958e.06 FALSE 395.1 Nonrheumatic mitral valve disorders Both 617 3202 8 circulatory system red 3202, 617 801, 159 800, 139 800, 161 801, 157 -0.0423 0.0441 0.337 0.4718 0.959 0.879 1.05 -0.129 0.126 0.308 0.512 0.879 0.686 1.13 0.013 0.124 0.916 0.03794 1.01 0.795 1.29 -0.0176 0.124 0.887 0.05204 0.983 0.771 1.25 PRS_PLINK_2.51188643150958e.06 FALSE 395.2 Nonrheumatic aortic valve disorders Both 635 2616 8 circulatory system red 2616, 635 654, 166 654, 138 654, 170 654, 160 -0.0443 0.045 0.325 0.4883 0.957 0.876 1.04 -0.166 0.13 0.199 0.7005 0.847 0.657 1.09 0.0469 0.125 0.707 0.1504 1.05 0.821 1.34 -0.0291 0.126 0.818 0.08742 0.971 0.758 1.24 PRS_PLINK_2.51188643150958e.06 FALSE 395.3 Nonrheumatic tricuspid valve disorders Both 187 726 8 circulatory system red 726, 187 182, 55 181, 44 181, 42 182, 45 -0.126 0.076 0.0963 1.016 0.881 0.759 1.02 -0.249 0.232 0.283 0.5489 0.779 0.495 1.23 -0.276 0.236 0.243 0.6153 0.759 0.478 1.21 -0.201 0.23 0.384 0.4155 0.818 0.521 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 395.4 Nonrheumatic pulmonary valve disorders Both 26 167 8 circulatory system red 167, 26 42, 6 42, 5 41, 6 42, 9 0.182 0.229 0.428 0.3688 1.2 0.765 1.88 -0.15 0.684 0.827 0.08261 0.861 0.225 3.29 0.362 0.661 0.584 0.2335 1.44 0.393 5.24 0.405 0.601 0.501 0.3006 1.5 0.462 4.86 PRS_PLINK_2.51188643150958e.06 TRUE 395.6 Heart valve replaced Both 305 1653 8 circulatory system red 1653, 305 414, 70 413, 73 413, 87 413, 74 -0.0148 0.0614 0.809 0.09191 0.985 0.874 1.11 0.0382 0.182 0.834 0.0789 1.04 0.727 1.48 0.245 0.177 0.165 0.7813 1.28 0.904 1.81 0.0409 0.182 0.823 0.08473 1.04 0.729 1.49 PRS_PLINK_2.51188643150958e.06 FALSE 396 Abnormal heart sounds Both 1273 5131 8 circulatory system red 5131, 1273 1283, 291 1283, 320 1282, 336 1283, 325 0.0183 0.0323 0.57 0.2439 1.02 0.956 1.08 0.0815 0.0913 0.372 0.4297 1.08 0.907 1.3 0.148 0.0908 0.104 0.9849 1.16 0.97 1.39 0.113 0.091 0.214 0.6705 1.12 0.937 1.34 PRS_PLINK_2.51188643150958e.06 FALSE 401 Hypertension Both 4887 2561 8 circulatory system red 2561, 4887 641, 1274 640, 1266 640, 1164 640, 1182 -0.0171 0.0272 0.531 0.2747 0.983 0.932 1.04 -0.0173 0.0768 0.822 0.0851 0.983 0.845 1.14 -0.101 0.0774 0.192 0.7177 0.904 0.777 1.05 -0.0778 0.0775 0.316 0.5007 0.925 0.795 1.08 PRS_PLINK_2.51188643150958e.06 FALSE 401.1 Essential hypertension Both 4845 2560 8 circulatory system red 2560, 4845 640, 1267 640, 1251 640, 1155 640, 1171 -0.0175 0.0273 0.521 0.2834 0.983 0.931 1.04 -0.0269 0.0771 0.727 0.1383 0.973 0.837 1.13 -0.104 0.0776 0.182 0.7401 0.902 0.774 1.05 -0.0807 0.0777 0.299 0.5248 0.922 0.792 1.07 PRS_PLINK_2.51188643150958e.06 FALSE 401.2 Hypertensive heart and/or renal disease Both 1332 1645 8 circulatory system red 1645, 1332 412, 351 411, 328 411, 332 411, 320 -0.0312 0.0394 0.429 0.368 0.969 0.897 1.05 -0.074 0.113 0.514 0.2893 0.929 0.744 1.16 -0.0134 0.114 0.907 0.04261 0.987 0.79 1.23 -0.102 0.113 0.367 0.435 0.903 0.723 1.13 PRS_PLINK_2.51188643150958e.06 FALSE 401.21 Hypertensive heart disease Both 377 752 8 circulatory system red 752, 377 188, 92 188, 87 188, 98 188, 100 0.0544 0.0631 0.389 0.4103 1.06 0.933 1.2 -0.0841 0.19 0.658 0.1815 0.919 0.633 1.33 0.141 0.188 0.453 0.3443 1.15 0.797 1.67 0.11 0.184 0.55 0.2593 1.12 0.778 1.6 PRS_PLINK_2.51188643150958e.06 FALSE 401.22 Hypertensive chronic kidney disease Both 981 1475 8 circulatory system red 1475, 981 369, 258 369, 230 368, 271 369, 221 -0.0303 0.043 0.481 0.318 0.97 0.892 1.06 -0.139 0.125 0.265 0.5768 0.87 0.681 1.11 0.0855 0.122 0.483 0.3163 1.09 0.858 1.38 -0.182 0.126 0.146 0.8347 0.833 0.652 1.07 PRS_PLINK_2.51188643150958e.06 FALSE 401.3 Other hypertensive complications Both 968 1783 8 circulatory system red 1783, 968 446, 258 446, 232 445, 252 446, 226 -0.0329 0.0405 0.416 0.3809 0.968 0.894 1.05 -0.0995 0.12 0.407 0.3904 0.905 0.715 1.15 0.039 0.119 0.743 0.1293 1.04 0.824 1.31 -0.123 0.12 0.305 0.5159 0.884 0.699 1.12 PRS_PLINK_2.51188643150958e.06 FALSE 411 Ischemic Heart Disease Both 2478 4067 8 circulatory system red 4067, 2478 1017, 667 1017, 540 1016, 628 1017, 642 0.0048 0.0273 0.86 0.06528 1 0.952 1.06 -0.22 0.078 0.00476 2.322 0.802 0.689 0.935 -0.0401 0.0767 0.601 0.2212 0.961 0.827 1.12 -0.0147 0.0766 0.848 0.07164 0.985 0.848 1.15 PRS_PLINK_2.51188643150958e.06 FALSE 411.1 Unstable angina (intermediate coronary syndrome) Both 425 1186 8 circulatory system red 1186, 425 297, 119 296, 81 296, 118 297, 107 0.00791 0.0582 0.892 0.04973 1.01 0.899 1.13 -0.344 0.167 0.0395 1.403 0.709 0.511 0.984 0.0425 0.156 0.785 0.105 1.04 0.769 1.42 -0.0634 0.16 0.692 0.1601 0.939 0.686 1.28 PRS_PLINK_2.51188643150958e.06 FALSE 411.2 Myocardial infarction Both 988 2851 8 circulatory system red 2851, 988 713, 277 713, 205 712, 262 713, 243 -0.0163 0.038 0.668 0.1749 0.984 0.913 1.06 -0.293 0.11 0.00758 2.12 0.746 0.602 0.925 -0.0356 0.106 0.736 0.133 0.965 0.785 1.19 -0.103 0.107 0.338 0.4711 0.902 0.732 1.11 PRS_PLINK_2.51188643150958e.06 FALSE 411.3 Angina pectoris Both 909 2432 8 circulatory system red 2432, 909 608, 230 608, 199 608, 246 608, 233 0.00728 0.0401 0.856 0.06766 1.01 0.931 1.09 -0.147 0.114 0.197 0.706 0.863 0.69 1.08 0.0723 0.111 0.515 0.288 1.07 0.865 1.34 0.000847 0.112 0.994 0.002631 1 0.804 1.25 PRS_PLINK_2.51188643150958e.06 FALSE 411.4 Coronary atherosclerosis Both 2164 3685 8 circulatory system red 3685, 2164 922, 584 921, 467 921, 545 921, 567 0.00666 0.029 0.819 0.08697 1.01 0.951 1.07 -0.243 0.0832 0.00354 2.451 0.784 0.666 0.923 -0.0598 0.0815 0.463 0.3343 0.942 0.803 1.11 -0.0138 0.081 0.865 0.06288 0.986 0.842 1.16 PRS_PLINK_2.51188643150958e.06 FALSE 411.41 Aneurysm and dissection of heart Both 59 204 8 circulatory system red 204, 59 51, 18 51, 18 51, 11 51, 12 -0.171 0.163 0.296 0.5282 0.843 0.612 1.16 0.0556 0.395 0.888 0.05156 1.06 0.488 2.29 -0.407 0.434 0.348 0.4581 0.665 0.284 1.56 -0.195 0.434 0.653 0.1849 0.823 0.351 1.93 PRS_PLINK_2.51188643150958e.06 FALSE 411.8 Other chronic ischemic heart disease, unspecified Both 1738 3395 8 circulatory system red 3395, 1738 849, 466 849, 364 848, 438 849, 469 0.0162 0.0315 0.608 0.2162 1.02 0.955 1.08 -0.263 0.0902 0.0035 2.456 0.768 0.644 0.917 -0.0587 0.0884 0.507 0.2952 0.943 0.793 1.12 0.0112 0.087 0.898 0.04672 1.01 0.853 1.2 PRS_PLINK_2.51188643150958e.06 FALSE 411.9 Other acute and subacute forms of ischemic heart disease Both 199 613 8 circulatory system red 613, 199 154, 37 153, 53 153, 62 153, 47 0.111 0.0902 0.218 0.6612 1.12 0.936 1.33 0.379 0.247 0.126 0.9003 1.46 0.899 2.37 0.581 0.244 0.0172 1.765 1.79 1.11 2.88 0.299 0.254 0.24 0.62 1.35 0.819 2.22 PRS_PLINK_2.51188643150958e.06 FALSE 414 Other forms of chronic heart disease Both 1099 3001 8 circulatory system red 3001, 1099 751, 291 750, 223 750, 285 750, 299 0.00117 0.0365 0.975 0.01121 1 0.932 1.08 -0.304 0.106 0.00406 2.391 0.738 0.6 0.908 -0.0236 0.101 0.815 0.08862 0.977 0.801 1.19 0.0159 0.1 0.873 0.05885 1.02 0.835 1.24 PRS_PLINK_2.51188643150958e.06 FALSE 414.2 ASCVD Both 291 967 8 circulatory system red 967, 291 242, 80 242, 50 241, 79 242, 82 0.0314 0.0702 0.654 0.1842 1.03 0.899 1.18 -0.473 0.204 0.0203 1.692 0.623 0.418 0.929 -0.0385 0.185 0.835 0.07812 0.962 0.669 1.38 0.0184 0.184 0.92 0.03604 1.02 0.711 1.46 PRS_PLINK_2.51188643150958e.06 FALSE 415 Pulmonary heart disease Both 1146 4512 8 circulatory system red 4512, 1146 1128, 300 1128, 251 1128, 303 1128, 291 0.0136 0.0334 0.685 0.1643 1.01 0.949 1.08 -0.183 0.0957 0.0555 1.256 0.833 0.69 1 0.0112 0.0922 0.903 0.04415 1.01 0.844 1.21 -0.0316 0.0931 0.734 0.134 0.969 0.807 1.16 PRS_PLINK_2.51188643150958e.06 FALSE 415.1 Acute pulmonary heart disease Both 636 2828 8 circulatory system red 2828, 636 707, 161 707, 148 707, 165 707, 161 0.0414 0.0453 0.361 0.4422 1.04 0.954 1.14 -0.0876 0.126 0.487 0.3129 0.916 0.716 1.17 0.0313 0.123 0.8 0.09699 1.03 0.81 1.31 0.0121 0.124 0.922 0.03509 1.01 0.794 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 415.11 Pulmonary embolism and infarction, acute Both 633 2830 8 circulatory system red 2830, 633 708, 160 707, 148 707, 162 708, 162 0.0428 0.0454 0.346 0.4614 1.04 0.955 1.14 -0.0793 0.126 0.529 0.2764 0.924 0.722 1.18 0.022 0.124 0.859 0.06589 1.02 0.802 1.3 0.0237 0.124 0.848 0.07163 1.02 0.803 1.31 PRS_PLINK_2.51188643150958e.06 FALSE 415.2 Chronic pulmonary heart disease Both 698 2781 8 circulatory system red 2781, 698 696, 198 695, 142 695, 176 695, 181 -0.0157 0.0419 0.709 0.1495 0.984 0.907 1.07 -0.335 0.123 0.00633 2.198 0.716 0.563 0.91 -0.108 0.117 0.356 0.4488 0.897 0.713 1.13 -0.0858 0.117 0.465 0.3329 0.918 0.729 1.16 PRS_PLINK_2.51188643150958e.06 FALSE 415.21 Primary pulmonary hypertension Both 301 1149 8 circulatory system red 1149, 301 288, 74 287, 59 287, 76 287, 92 0.135 0.0721 0.0605 1.218 1.14 0.994 1.32 -0.211 0.194 0.277 0.5582 0.809 0.553 1.18 0.0196 0.185 0.916 0.03823 1.02 0.709 1.47 0.207 0.181 0.252 0.5985 1.23 0.863 1.75 PRS_PLINK_2.51188643150958e.06 FALSE 416 Cardiomegaly Both 485 1915 8 circulatory system red 1915, 485 479, 113 479, 107 478, 143 479, 122 0.099 0.0533 0.0633 1.199 1.1 0.995 1.23 -0.0497 0.15 0.741 0.1304 0.952 0.709 1.28 0.238 0.143 0.0951 1.022 1.27 0.959 1.68 0.064 0.147 0.663 0.1784 1.07 0.799 1.42 PRS_PLINK_2.51188643150958e.06 FALSE 418 Nonspecific chest pain Both 4247 3167 8 circulatory system red 3167, 4247 792, 1040 792, 1085 791, 1115 792, 1006 0.00681 0.0239 0.775 0.1105 1.01 0.961 1.06 0.0355 0.0678 0.6 0.2215 1.04 0.907 1.18 0.0789 0.0676 0.243 0.6145 1.08 0.948 1.24 -0.0296 0.0683 0.665 0.1774 0.971 0.849 1.11 PRS_PLINK_2.51188643150958e.06 FALSE 418.1 Precordial pain Both 653 1441 8 circulatory system red 1441, 653 361, 171 360, 164 360, 171 360, 147 -0.0419 0.0478 0.381 0.419 0.959 0.873 1.05 -0.0163 0.134 0.903 0.04423 0.984 0.757 1.28 0.0174 0.133 0.896 0.04774 1.02 0.784 1.32 -0.133 0.137 0.331 0.4796 0.876 0.67 1.14 PRS_PLINK_2.51188643150958e.06 FALSE 420 Carditis Both 583 2460 8 circulatory system red 2460, 583 615, 140 615, 145 615, 137 615, 160 0.00661 0.0454 0.884 0.05345 1.01 0.921 1.1 0.0647 0.132 0.625 0.2042 1.07 0.823 1.38 0.0194 0.134 0.885 0.05304 1.02 0.784 1.33 0.173 0.13 0.185 0.7333 1.19 0.921 1.54 PRS_PLINK_2.51188643150958e.06 FALSE 420.1 Myocarditis Both 33 121 8 circulatory system red 121, 33 31, 8 30, 7 30, 9 30, 9 -0.0185 0.234 0.937 0.02828 0.982 0.621 1.55 -0.0043 0.601 0.994 0.002486 0.996 0.307 3.23 0.153 0.588 0.795 0.09952 1.16 0.368 3.69 0.165 0.603 0.785 0.1053 1.18 0.362 3.85 PRS_PLINK_2.51188643150958e.06 TRUE 420.2 Pericarditis Both 336 1285 8 circulatory system red 1285, 336 322, 84 321, 79 321, 79 321, 94 -0.0168 0.0599 0.78 0.1081 0.983 0.874 1.11 -0.0242 0.176 0.891 0.05014 0.976 0.691 1.38 -0.0325 0.177 0.854 0.06839 0.968 0.684 1.37 0.123 0.171 0.475 0.3237 1.13 0.808 1.58 PRS_PLINK_2.51188643150958e.06 FALSE 420.21 Acute pericarditis Both 75 249 8 circulatory system red 249, 75 63, 24 62, 19 62, 14 62, 18 -0.117 0.128 0.364 0.4384 0.89 0.692 1.14 -0.247 0.37 0.505 0.2965 0.781 0.378 1.61 -0.415 0.385 0.282 0.5504 0.661 0.311 1.41 -0.199 0.38 0.6 0.2221 0.819 0.389 1.72 PRS_PLINK_2.51188643150958e.06 FALSE 420.22 Chronic pericarditis Both 50 168 8 circulatory system red 168, 50 42, 11 42, 13 42, 13 42, 13 0.132 0.17 0.436 0.3608 1.14 0.818 1.59 0.254 0.479 0.596 0.2246 1.29 0.504 3.3 0.182 0.474 0.701 0.1541 1.2 0.474 3.04 0.0126 0.509 0.98 0.008642 1.01 0.373 2.75 PRS_PLINK_2.51188643150958e.06 TRUE 420.3 Endocarditis Both 272 1258 8 circulatory system red 1258, 272 315, 62 314, 74 314, 61 315, 74 -0.000893 0.0672 0.989 0.00463 0.999 0.876 1.14 0.209 0.191 0.275 0.5601 1.23 0.847 1.79 0.0727 0.2 0.716 0.1452 1.08 0.727 1.59 0.229 0.192 0.233 0.633 1.26 0.863 1.83 PRS_PLINK_2.51188643150958e.06 FALSE 425 Cardiomyopathy Both 710 3016 8 circulatory system red 3016, 710 754, 182 754, 148 754, 181 754, 198 0.0485 0.043 0.26 0.5858 1.05 0.965 1.14 -0.201 0.123 0.102 0.9907 0.818 0.643 1.04 0.00135 0.118 0.991 0.003989 1 0.795 1.26 0.082 0.116 0.478 0.3209 1.09 0.866 1.36 PRS_PLINK_2.51188643150958e.06 FALSE 425.1 Primary/intrinsic cardiomyopathies Both 679 2902 8 circulatory system red 2902, 679 726, 177 725, 136 725, 175 726, 190 0.0531 0.0437 0.224 0.6504 1.05 0.968 1.15 -0.263 0.126 0.0367 1.435 0.769 0.6 0.984 -0.00243 0.119 0.984 0.007106 0.998 0.789 1.26 0.0695 0.117 0.554 0.2568 1.07 0.852 1.35 PRS_PLINK_2.51188643150958e.06 FALSE 425.11 Hypertrophic obstructive cardiomyopathy Both 71 301 8 circulatory system red 301, 71 76, 22 75, 16 75, 15 75, 18 0.0153 0.139 0.912 0.03995 1.02 0.773 1.33 -0.36 0.374 0.336 0.4736 0.698 0.335 1.45 -0.371 0.376 0.323 0.4907 0.69 0.33 1.44 -0.206 0.361 0.568 0.2455 0.814 0.401 1.65 PRS_PLINK_2.51188643150958e.06 FALSE 425.12 Other hypertrophic cardiomyopathy Both 59 275 8 circulatory system red 275, 59 69, 13 69, 10 68, 14 69, 22 0.309 0.169 0.067 1.174 1.36 0.979 1.89 -0.14 0.472 0.766 0.1156 0.869 0.344 2.19 0.169 0.423 0.688 0.1621 1.18 0.517 2.71 0.51 0.394 0.196 0.7084 1.67 0.769 3.61 PRS_PLINK_2.51188643150958e.06 FALSE 425.2 Secondary/extrinsic cardiomyopathies Both 121 454 8 circulatory system red 454, 121 114, 30 113, 23 113, 30 114, 38 0.121 0.109 0.267 0.5742 1.13 0.911 1.4 -0.255 0.306 0.406 0.3917 0.775 0.425 1.41 -0.0315 0.296 0.915 0.03847 0.969 0.542 1.73 0.168 0.282 0.551 0.2586 1.18 0.68 2.06 PRS_PLINK_2.51188643150958e.06 FALSE 425.8 Other cardiomyopathy Both 41 152 8 circulatory system red 152, 41 38, 13 38, 7 38, 11 38, 10 -0.0663 0.157 0.673 0.1719 0.936 0.688 1.27 -0.858 0.56 0.125 0.9017 0.424 0.141 1.27 -0.153 0.483 0.751 0.1243 0.858 0.333 2.21 -0.374 0.492 0.447 0.3498 0.688 0.263 1.8 PRS_PLINK_2.51188643150958e.06 TRUE 426 Cardiac conduction disorders Both 3799 2141 8 circulatory system red 2141, 3799 536, 897 535, 935 535, 991 535, 975 0.0292 0.0289 0.313 0.5051 1.03 0.973 1.09 0.024 0.0827 0.771 0.1127 1.02 0.871 1.2 0.106 0.0818 0.195 0.7096 1.11 0.947 1.31 0.0927 0.0826 0.262 0.5822 1.1 0.933 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 426.2 Atrioventricular [AV] block Both 704 958 8 circulatory system red 958, 704 240, 187 239, 162 239, 169 240, 186 -0.0203 0.0533 0.704 0.1526 0.98 0.883 1.09 -0.123 0.15 0.412 0.3847 0.884 0.659 1.19 -0.0542 0.147 0.712 0.1477 0.947 0.71 1.26 0.0246 0.147 0.867 0.06184 1.02 0.768 1.37 PRS_PLINK_2.51188643150958e.06 FALSE 426.21 First degree AV block Both 489 751 8 circulatory system red 751, 489 188, 119 188, 110 187, 126 188, 134 0.0328 0.0615 0.593 0.2268 1.03 0.916 1.17 -0.0827 0.178 0.642 0.1924 0.921 0.65 1.3 0.0776 0.172 0.652 0.1854 1.08 0.771 1.52 0.158 0.172 0.358 0.4459 1.17 0.836 1.64 PRS_PLINK_2.51188643150958e.06 FALSE 426.22 Mobitz II AV block Both 31 52 8 circulatory system red 52, 31 13, 6 13, 5 13, 5 13, 15 0.349 0.326 0.285 0.5455 1.42 0.748 2.69 -0.855 0.878 0.33 0.4812 0.425 0.076 2.38 -0.266 0.802 0.74 0.1305 0.767 0.159 3.69 0.983 0.769 0.201 0.6969 2.67 0.592 12.1 PRS_PLINK_2.51188643150958e.06 TRUE 426.23 Second degree AV block Both 95 179 8 circulatory system red 179, 95 45, 33 45, 16 44, 22 45, 24 -0.0742 0.138 0.59 0.2294 0.928 0.709 1.22 -0.71 0.385 0.0655 1.184 0.492 0.231 1.05 -0.364 0.36 0.312 0.5063 0.695 0.343 1.41 -0.331 0.348 0.342 0.4663 0.718 0.363 1.42 PRS_PLINK_2.51188643150958e.06 FALSE 426.24 Atrioventricular block, complete Both 176 316 8 circulatory system red 316, 176 79, 52 79, 38 79, 43 79, 43 -0.113 0.0959 0.241 0.6182 0.894 0.74 1.08 -0.241 0.281 0.392 0.4063 0.786 0.453 1.36 -0.177 0.271 0.513 0.2901 0.837 0.492 1.42 -0.141 0.285 0.622 0.2062 0.869 0.497 1.52 PRS_PLINK_2.51188643150958e.06 FALSE 426.25 Other heart block Both 98 146 8 circulatory system red 146, 98 37, 28 36, 22 36, 24 37, 24 -0.0877 0.156 0.574 0.2413 0.916 0.675 1.24 -0.298 0.39 0.446 0.3508 0.743 0.346 1.6 -0.0705 0.384 0.855 0.06827 0.932 0.439 1.98 -0.259 0.389 0.506 0.2959 0.772 0.36 1.65 PRS_PLINK_2.51188643150958e.06 FALSE 426.3 Bundle branch block Both 762 1165 8 circulatory system red 1165, 762 292, 182 291, 171 291, 193 291, 215 0.0479 0.0482 0.32 0.4944 1.05 0.955 1.15 -0.0738 0.144 0.607 0.2169 0.929 0.701 1.23 0.108 0.14 0.444 0.3528 1.11 0.846 1.47 0.199 0.139 0.153 0.8161 1.22 0.929 1.6 PRS_PLINK_2.51188643150958e.06 FALSE 426.31 Right bundle branch block Both 467 884 8 circulatory system red 884, 467 221, 110 221, 107 221, 119 221, 131 0.0377 0.0573 0.51 0.2922 1.04 0.928 1.16 -0.0515 0.172 0.765 0.1164 0.95 0.678 1.33 0.0978 0.167 0.559 0.2527 1.1 0.794 1.53 0.19 0.167 0.254 0.5949 1.21 0.872 1.68 PRS_PLINK_2.51188643150958e.06 FALSE 426.32 Left bundle branch block Both 339 685 8 circulatory system red 685, 339 172, 86 171, 66 171, 90 171, 96 0.0747 0.0699 0.285 0.545 1.08 0.94 1.24 -0.216 0.203 0.288 0.5413 0.806 0.542 1.2 0.0745 0.196 0.704 0.1523 1.08 0.733 1.58 0.228 0.195 0.242 0.6162 1.26 0.857 1.84 PRS_PLINK_2.51188643150958e.06 FALSE 426.4 Anomalous atrioventricular excitation Both 16 62 8 circulatory system red 62, 16 16, 5 15, 2 15, 3 16, 6 -0.0894 0.266 0.737 0.1328 0.915 0.543 1.54 -0.358 0.903 0.692 0.1599 0.699 0.119 4.1 -0.182 0.844 0.829 0.08143 0.833 0.159 4.36 -0.35 0.827 0.672 0.1724 0.705 0.139 3.57 PRS_PLINK_2.51188643150958e.06 TRUE 426.7 Abnormal electrocardiogram [ECG] [EKG] Both 3518 2131 8 circulatory system red 2131, 3518 533, 831 533, 864 532, 916 533, 906 0.0302 0.0294 0.304 0.517 1.03 0.973 1.09 0.0349 0.0839 0.677 0.1691 1.04 0.879 1.22 0.11 0.0833 0.188 0.7269 1.12 0.948 1.31 0.106 0.084 0.205 0.688 1.11 0.943 1.31 PRS_PLINK_2.51188643150958e.06 FALSE 426.8 Other cardiac conduction disorders Both 317 608 8 circulatory system red 608, 317 152, 77 152, 76 152, 88 152, 76 0.02 0.0732 0.785 0.1052 1.02 0.884 1.18 0.00832 0.203 0.967 0.01442 1.01 0.677 1.5 0.12 0.196 0.543 0.2653 1.13 0.767 1.66 0.0155 0.202 0.939 0.02746 1.02 0.684 1.51 PRS_PLINK_2.51188643150958e.06 FALSE 426.9 Cardiac pacemaker/device in situ Both 502 936 8 circulatory system red 936, 502 234, 130 234, 106 234, 140 234, 125 -0.0104 0.0586 0.859 0.06613 0.99 0.882 1.11 -0.152 0.167 0.363 0.4407 0.859 0.619 1.19 0.138 0.16 0.388 0.4111 1.15 0.839 1.57 -0.00541 0.165 0.974 0.01152 0.995 0.72 1.37 PRS_PLINK_2.51188643150958e.06 FALSE 426.91 Cardiac pacemaker in situ Both 346 663 8 circulatory system red 663, 346 166, 88 166, 80 165, 97 166, 80 -0.0283 0.0691 0.682 0.1661 0.972 0.849 1.11 -0.0379 0.197 0.847 0.07197 0.963 0.655 1.42 0.15 0.192 0.435 0.3616 1.16 0.797 1.69 -0.0352 0.202 0.862 0.06473 0.965 0.65 1.43 PRS_PLINK_2.51188643150958e.06 FALSE 426.92 Cardiac defibrillator in situ Both 282 583 8 circulatory system red 583, 282 146, 78 146, 55 145, 78 146, 70 -0.0605 0.076 0.426 0.3705 0.941 0.811 1.09 -0.306 0.22 0.165 0.7825 0.737 0.478 1.13 0.0596 0.205 0.771 0.113 1.06 0.711 1.58 -0.0422 0.212 0.842 0.07473 0.959 0.633 1.45 PRS_PLINK_2.51188643150958e.06 FALSE 427 Cardiac dysrhythmias Both 4561 2150 8 circulatory system red 2150, 4561 538, 1089 537, 1152 537, 1204 538, 1115 0.0117 0.0272 0.668 0.1751 1.01 0.959 1.07 0.0565 0.0773 0.465 0.333 1.06 0.909 1.23 0.104 0.0771 0.177 0.7514 1.11 0.954 1.29 0.037 0.0777 0.634 0.1981 1.04 0.891 1.21 PRS_PLINK_2.51188643150958e.06 FALSE 427.1 Paroxysmal tachycardia, unspecified Both 801 1579 8 circulatory system red 1579, 801 395, 197 395, 180 394, 205 395, 218 0.066 0.0459 0.151 0.8216 1.07 0.976 1.17 -0.0438 0.13 0.736 0.1329 0.957 0.742 1.24 0.0852 0.128 0.505 0.297 1.09 0.848 1.4 0.156 0.127 0.221 0.6556 1.17 0.911 1.5 PRS_PLINK_2.51188643150958e.06 FALSE 427.11 Paroxysmal supraventricular tachycardia Both 532 1238 8 circulatory system red 1238, 532 310, 129 309, 124 309, 132 310, 147 0.0514 0.055 0.35 0.4559 1.05 0.945 1.17 -0.00894 0.152 0.953 0.02088 0.991 0.736 1.33 0.059 0.151 0.695 0.1579 1.06 0.79 1.42 0.164 0.149 0.269 0.5701 1.18 0.881 1.58 PRS_PLINK_2.51188643150958e.06 FALSE 427.12 Paroxysmal ventricular tachycardia Both 406 821 8 circulatory system red 821, 406 206, 92 205, 75 205, 117 205, 121 0.114 0.0651 0.0812 1.09 1.12 0.986 1.27 -0.171 0.19 0.369 0.4328 0.843 0.581 1.22 0.28 0.176 0.111 0.9539 1.32 0.938 1.87 0.296 0.177 0.095 1.022 1.34 0.95 1.9 PRS_PLINK_2.51188643150958e.06 FALSE 427.2 Atrial fibrillation and flutter Both 1388 1578 8 circulatory system red 1578, 1388 395, 331 394, 321 394, 379 395, 356 0.0538 0.0418 0.198 0.7026 1.06 0.972 1.15 -0.00124 0.118 0.992 0.003667 0.999 0.793 1.26 0.179 0.116 0.121 0.916 1.2 0.954 1.5 0.127 0.118 0.282 0.55 1.14 0.901 1.43 PRS_PLINK_2.51188643150958e.06 FALSE 427.21 Atrial fibrillation Both 1368 1556 8 circulatory system red 1556, 1368 389, 322 389, 316 389, 375 389, 354 0.0664 0.0421 0.115 0.9396 1.07 0.984 1.16 0.0251 0.119 0.833 0.07938 1.03 0.812 1.29 0.206 0.116 0.0772 1.113 1.23 0.978 1.54 0.153 0.119 0.197 0.7047 1.17 0.923 1.47 PRS_PLINK_2.51188643150958e.06 FALSE 427.22 Atrial flutter Both 528 906 8 circulatory system red 906, 528 227, 118 226, 119 226, 145 227, 145 0.0547 0.0583 0.348 0.4585 1.06 0.942 1.18 -0.0108 0.171 0.949 0.02253 0.989 0.708 1.38 0.217 0.164 0.185 0.7318 1.24 0.901 1.71 0.223 0.167 0.18 0.7437 1.25 0.902 1.73 PRS_PLINK_2.51188643150958e.06 FALSE 427.3 Other specified cardiac dysrhythmias Both 2684 2137 8 circulatory system red 2137, 2684 535, 673 534, 675 534, 697 534, 639 -0.0145 0.0306 0.636 0.1963 0.986 0.928 1.05 0.0143 0.0871 0.869 0.06089 1.01 0.855 1.2 0.0552 0.0871 0.526 0.2792 1.06 0.891 1.25 -0.0448 0.0887 0.613 0.2123 0.956 0.804 1.14 PRS_PLINK_2.51188643150958e.06 FALSE 427.4 Cardiac arrest and ventricular fibrillation Both 190 459 8 circulatory system red 459, 190 115, 47 115, 43 114, 45 115, 55 0.119 0.0951 0.209 0.68 1.13 0.935 1.36 -0.01 0.254 0.969 0.01388 0.99 0.601 1.63 -0.00592 0.251 0.981 0.008252 0.994 0.608 1.63 0.215 0.244 0.378 0.4225 1.24 0.768 2 PRS_PLINK_2.51188643150958e.06 FALSE 427.41 Ventricular fibrillation and flutter Both 75 189 8 circulatory system red 189, 75 48, 16 47, 14 47, 23 47, 22 0.152 0.167 0.362 0.441 1.16 0.839 1.61 -0.149 0.438 0.733 0.1348 0.861 0.365 2.03 0.383 0.396 0.333 0.4775 1.47 0.675 3.19 0.432 0.409 0.292 0.5352 1.54 0.69 3.44 PRS_PLINK_2.51188643150958e.06 FALSE 427.42 Cardiac arrest Both 152 364 8 circulatory system red 364, 152 91, 40 91, 37 91, 31 91, 44 0.111 0.111 0.316 0.4997 1.12 0.899 1.39 -0.0132 0.279 0.962 0.01667 0.987 0.572 1.7 -0.203 0.29 0.483 0.3161 0.816 0.462 1.44 0.149 0.271 0.582 0.2348 1.16 0.683 1.97 PRS_PLINK_2.51188643150958e.06 FALSE 427.5 Arrhythmia (cardiac) NOS Both 2040 2136 8 circulatory system red 2136, 2040 534, 461 534, 524 534, 556 534, 498 0.0278 0.0337 0.409 0.3883 1.03 0.962 1.1 0.129 0.0947 0.173 0.7617 1.14 0.945 1.37 0.196 0.0945 0.0383 1.417 1.22 1.01 1.46 0.0997 0.0959 0.299 0.5245 1.1 0.915 1.33 PRS_PLINK_2.51188643150958e.06 FALSE 427.6 Premature beats Both 826 1432 8 circulatory system red 1432, 826 358, 210 358, 198 358, 205 358, 213 0.0634 0.0478 0.185 0.7338 1.07 0.97 1.17 -0.0256 0.131 0.845 0.07324 0.975 0.754 1.26 0.0195 0.131 0.882 0.05466 1.02 0.788 1.32 0.0492 0.131 0.707 0.1509 1.05 0.813 1.36 PRS_PLINK_2.51188643150958e.06 FALSE 427.61 Supraventricular premature beats Both 266 597 8 circulatory system red 597, 266 150, 67 149, 60 149, 64 149, 75 0.0285 0.081 0.725 0.1394 1.03 0.878 1.21 -0.0232 0.219 0.916 0.0383 0.977 0.636 1.5 0.0655 0.216 0.762 0.1182 1.07 0.699 1.63 0.121 0.213 0.571 0.2436 1.13 0.743 1.71 PRS_PLINK_2.51188643150958e.06 FALSE 427.7 Tachycardia NOS Both 1803 2141 8 circulatory system red 2141, 1803 536, 445 535, 437 535, 468 535, 453 0.00577 0.0324 0.859 0.06622 1.01 0.944 1.07 -0.0183 0.0932 0.844 0.07343 0.982 0.818 1.18 0.0569 0.0921 0.537 0.2702 1.06 0.884 1.27 0.0241 0.0929 0.795 0.09958 1.02 0.854 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 427.8 Sinoatrial node dysfunction (Bradycardia) Both 341 639 8 circulatory system red 639, 341 160, 89 160, 77 159, 89 160, 86 -0.0088 0.0691 0.899 0.04641 0.991 0.866 1.13 -0.11 0.201 0.585 0.2328 0.896 0.604 1.33 0.131 0.196 0.504 0.2975 1.14 0.776 1.67 0.0737 0.2 0.713 0.147 1.08 0.727 1.59 PRS_PLINK_2.51188643150958e.06 FALSE 427.9 Palpitations Both 1606 2103 8 circulatory system red 2103, 1606 526, 379 526, 409 525, 412 526, 406 0.0355 0.0346 0.305 0.5153 1.04 0.968 1.11 0.0593 0.0976 0.544 0.2645 1.06 0.876 1.28 0.112 0.0971 0.249 0.603 1.12 0.925 1.35 0.116 0.0974 0.232 0.6337 1.12 0.928 1.36 PRS_PLINK_2.51188643150958e.06 FALSE 428 Congestive heart failure; nonhypertensive Both 1413 2482 8 circulatory system red 2482, 1413 621, 347 620, 310 620, 381 621, 374 0.0373 0.0353 0.291 0.5368 1.04 0.969 1.11 -0.0796 0.103 0.438 0.3585 0.924 0.755 1.13 0.0991 0.0995 0.319 0.4957 1.1 0.909 1.34 0.0989 0.099 0.318 0.4975 1.1 0.909 1.34 PRS_PLINK_2.51188643150958e.06 FALSE 428.1 Congestive heart failure (CHF) NOS Both 1260 2348 8 circulatory system red 2348, 1260 587, 314 587, 278 587, 342 587, 325 0.0272 0.0369 0.462 0.3354 1.03 0.956 1.1 -0.103 0.107 0.334 0.4767 0.902 0.732 1.11 0.091 0.103 0.377 0.4237 1.1 0.895 1.34 0.0514 0.103 0.619 0.2081 1.05 0.86 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 428.2 Heart failure NOS Both 1217 2257 8 circulatory system red 2257, 1217 565, 295 564, 264 564, 331 564, 326 0.06 0.0379 0.113 0.9452 1.06 0.986 1.14 -0.0697 0.11 0.525 0.2799 0.933 0.752 1.16 0.132 0.106 0.213 0.671 1.14 0.927 1.4 0.141 0.105 0.178 0.7494 1.15 0.938 1.41 PRS_PLINK_2.51188643150958e.06 FALSE 428.3 Heart failure with reduced EF [Systolic or combined heart failure] Both 649 1450 8 circulatory system red 1450, 649 363, 159 362, 131 362, 177 363, 181 0.0533 0.0495 0.282 0.5492 1.05 0.957 1.16 -0.131 0.144 0.363 0.44 0.877 0.661 1.16 0.151 0.136 0.266 0.575 1.16 0.891 1.52 0.155 0.135 0.249 0.6031 1.17 0.897 1.52 PRS_PLINK_2.51188643150958e.06 FALSE 428.4 Heart failure with preserved EF [Diastolic heart failure] Both 710 1401 8 circulatory system red 1401, 710 351, 182 350, 140 350, 192 350, 195 0.0356 0.0475 0.452 0.3444 1.04 0.944 1.14 -0.252 0.138 0.069 1.161 0.777 0.593 1.02 0.0638 0.131 0.626 0.2033 1.07 0.825 1.38 0.0955 0.13 0.462 0.3352 1.1 0.853 1.42 PRS_PLINK_2.51188643150958e.06 FALSE 429 Ill-defined descriptions and complications of heart disease Both 3915 3306 8 circulatory system red 3306, 3915 827, 955 826, 968 826, 999 827, 992 0.0189 0.0244 0.437 0.3591 1.02 0.972 1.07 0.00939 0.0696 0.893 0.04929 1.01 0.881 1.16 0.0431 0.0693 0.534 0.2723 1.04 0.911 1.2 0.0454 0.0694 0.513 0.2896 1.05 0.913 1.2 PRS_PLINK_2.51188643150958e.06 FALSE 429.1 Heart transplant/surgery Both 373 1183 8 circulatory system red 1183, 373 296, 91 296, 71 295, 113 296, 97 0.0612 0.0606 0.312 0.5057 1.06 0.944 1.2 -0.23 0.181 0.204 0.6901 0.794 0.557 1.13 0.22 0.164 0.181 0.7424 1.25 0.903 1.72 0.0671 0.17 0.693 0.1595 1.07 0.767 1.49 PRS_PLINK_2.51188643150958e.06 FALSE 429.2 Abnormal function study of cardiovascular system Both 2367 3095 8 circulatory system red 3095, 2367 774, 575 774, 571 773, 605 774, 615 0.0345 0.029 0.233 0.6317 1.04 0.978 1.1 0.0135 0.0821 0.869 0.06092 1.01 0.863 1.19 0.0564 0.0817 0.49 0.3098 1.06 0.901 1.24 0.0886 0.0813 0.276 0.5594 1.09 0.932 1.28 PRS_PLINK_2.51188643150958e.06 FALSE 429.3 Symptoms involving cardiovascular system Both 3101 3305 8 circulatory system red 3305, 3101 827, 774 826, 770 826, 788 826, 769 0.00816 0.0256 0.75 0.1248 1.01 0.959 1.06 -0.00213 0.0732 0.977 0.0102 0.998 0.865 1.15 0.0216 0.0729 0.767 0.115 1.02 0.886 1.18 0.011 0.0731 0.88 0.05555 1.01 0.876 1.17 PRS_PLINK_2.51188643150958e.06 FALSE 429.9 Cardiac complications, not elsewhere classified Both 196 720 8 circulatory system red 720, 196 180, 51 180, 43 180, 54 180, 48 0.024 0.0802 0.765 0.1163 1.02 0.875 1.2 -0.186 0.236 0.432 0.3641 0.831 0.523 1.32 0.0483 0.225 0.83 0.08077 1.05 0.675 1.63 -0.0771 0.23 0.737 0.1326 0.926 0.59 1.45 PRS_PLINK_2.51188643150958e.06 FALSE 430 Intracranial hemorrhage Both 254 1186 8 circulatory system red 1186, 254 297, 67 296, 49 296, 68 297, 70 -0.0191 0.0696 0.783 0.106 0.981 0.856 1.12 -0.304 0.206 0.14 0.8542 0.738 0.493 1.1 0.0919 0.193 0.635 0.1973 1.1 0.75 1.6 0.0675 0.191 0.724 0.1402 1.07 0.735 1.56 PRS_PLINK_2.51188643150958e.06 FALSE 430.1 Subarachnoid hemorrhage Both 74 383 8 circulatory system red 383, 74 96, 21 96, 10 95, 23 96, 20 -0.046 0.14 0.743 0.1293 0.955 0.726 1.26 -0.601 0.404 0.137 0.8636 0.548 0.248 1.21 0.166 0.347 0.631 0.1998 1.18 0.599 2.33 -0.0825 0.355 0.816 0.08821 0.921 0.459 1.85 PRS_PLINK_2.51188643150958e.06 FALSE 430.2 Intracerebral hemorrhage Both 118 568 8 circulatory system red 568, 118 142, 32 142, 27 142, 33 142, 26 -0.000427 0.104 0.997 0.001428 1 0.815 1.23 -0.164 0.291 0.572 0.2425 0.849 0.48 1.5 0.0742 0.28 0.791 0.1017 1.08 0.622 1.87 -0.191 0.295 0.517 0.2864 0.826 0.464 1.47 PRS_PLINK_2.51188643150958e.06 FALSE 430.3 Subdural hemorrhage Both 91 397 8 circulatory system red 397, 91 100, 23 99, 15 99, 22 99, 31 0.0921 0.124 0.458 0.3392 1.1 0.86 1.4 -0.388 0.359 0.28 0.5525 0.679 0.336 1.37 -0.0168 0.336 0.96 0.0177 0.983 0.509 1.9 0.306 0.314 0.33 0.4808 1.36 0.733 2.51 PRS_PLINK_2.51188643150958e.06 FALSE 433 Cerebrovascular disease Both 1607 4785 8 circulatory system red 4785, 1607 1197, 415 1196, 379 1196, 420 1196, 392 0.0187 0.0299 0.532 0.274 1.02 0.961 1.08 -0.0947 0.0845 0.262 0.5816 0.91 0.771 1.07 0.026 0.083 0.754 0.1228 1.03 0.872 1.21 -0.0424 0.0842 0.614 0.2115 0.958 0.813 1.13 PRS_PLINK_2.51188643150958e.06 FALSE 433.1 Occlusion and stenosis of precerebral arteries Both 689 2510 8 circulatory system red 2510, 689 628, 177 627, 174 627, 171 628, 166 -0.00289 0.0433 0.947 0.02377 0.997 0.916 1.09 -0.015 0.121 0.902 0.04488 0.985 0.777 1.25 -0.0216 0.123 0.861 0.06524 0.979 0.77 1.24 -0.0313 0.124 0.8 0.09668 0.969 0.76 1.24 PRS_PLINK_2.51188643150958e.06 FALSE 433.11 Occlusion of cerebral arteries, with cerebral infarction Both 105 396 8 circulatory system red 396, 105 99, 29 99, 25 99, 27 99, 24 0.0516 0.118 0.662 0.1789 1.05 0.835 1.33 -0.176 0.316 0.577 0.2387 0.839 0.452 1.56 -0.0382 0.308 0.901 0.04511 0.963 0.526 1.76 -0.163 0.32 0.611 0.2139 0.85 0.454 1.59 PRS_PLINK_2.51188643150958e.06 FALSE 433.12 Cerebral atherosclerosis Both 41 112 8 circulatory system red 112, 41 28, 7 28, 10 28, 13 28, 11 0.201 0.227 0.374 0.4272 1.22 0.785 1.91 0.322 0.593 0.587 0.2312 1.38 0.432 4.41 1 0.617 0.104 0.9843 2.73 0.814 9.16 0.687 0.598 0.251 0.6005 1.99 0.615 6.42 PRS_PLINK_2.51188643150958e.06 TRUE 433.2 Occlusion of cerebral arteries Both 728 3294 8 circulatory system red 3294, 728 824, 193 823, 176 823, 191 824, 168 0.0137 0.0411 0.739 0.1316 1.01 0.935 1.1 -0.0935 0.116 0.419 0.3777 0.911 0.726 1.14 -0.00149 0.114 0.99 0.00456 0.999 0.799 1.25 -0.156 0.118 0.186 0.7309 0.855 0.679 1.08 PRS_PLINK_2.51188643150958e.06 FALSE 433.21 Cerebral artery occlusion, with cerebral infarction Both 707 3204 8 circulatory system red 3204, 707 801, 185 801, 171 801, 190 801, 161 0.017 0.0418 0.685 0.1646 1.02 0.937 1.1 -0.0817 0.118 0.488 0.3119 0.922 0.732 1.16 0.0296 0.115 0.798 0.09817 1.03 0.822 1.29 -0.161 0.12 0.181 0.7429 0.851 0.673 1.08 PRS_PLINK_2.51188643150958e.06 FALSE 433.3 Cerebral ischemia Both 904 3424 8 circulatory system red 3424, 904 856, 239 856, 204 856, 265 856, 195 -0.0149 0.0374 0.691 0.1607 0.985 0.916 1.06 -0.176 0.108 0.105 0.9768 0.839 0.678 1.04 0.0972 0.102 0.342 0.4662 1.1 0.902 1.35 -0.218 0.109 0.046 1.337 0.804 0.649 0.996 PRS_PLINK_2.51188643150958e.06 FALSE 433.31 Transient cerebral ischemia Both 776 3132 8 circulatory system red 3132, 776 783, 204 783, 170 783, 235 783, 166 -0.0226 0.0398 0.571 0.2436 0.978 0.904 1.06 -0.186 0.116 0.109 0.961 0.83 0.66 1.04 0.136 0.109 0.211 0.6762 1.15 0.926 1.42 -0.222 0.117 0.0577 1.239 0.801 0.636 1.01 PRS_PLINK_2.51188643150958e.06 FALSE 433.5 Cerebral aneurysm Both 85 767 8 circulatory system red 767, 85 192, 20 192, 22 191, 24 192, 19 0.0516 0.12 0.666 0.1763 1.05 0.833 1.33 0.133 0.323 0.679 0.1679 1.14 0.607 2.15 0.214 0.317 0.5 0.3011 1.24 0.666 2.3 -0.117 0.34 0.731 0.1359 0.89 0.457 1.73 PRS_PLINK_2.51188643150958e.06 FALSE 433.6 Acute, but ill-defined cerebrovascular disease Both 234 745 8 circulatory system red 745, 234 187, 62 186, 54 186, 65 186, 53 0.0108 0.0772 0.889 0.0511 1.01 0.869 1.18 -0.0883 0.217 0.684 0.1652 0.915 0.599 1.4 0.0857 0.207 0.68 0.1678 1.09 0.725 1.64 -0.114 0.216 0.599 0.2227 0.893 0.585 1.36 PRS_PLINK_2.51188643150958e.06 FALSE 433.8 Late effects of cerebrovascular disease Both 288 997 8 circulatory system red 997, 288 250, 89 249, 66 249, 66 249, 67 -0.0705 0.0639 0.27 0.5679 0.932 0.822 1.06 -0.261 0.187 0.161 0.7918 0.77 0.534 1.11 -0.262 0.187 0.162 0.7901 0.77 0.534 1.11 -0.279 0.188 0.138 0.86 0.757 0.523 1.09 PRS_PLINK_2.51188643150958e.06 FALSE 440 Atherosclerosis Both 947 2590 8 circulatory system red 2590, 947 648, 238 647, 232 647, 249 648, 228 0.0301 0.039 0.44 0.3565 1.03 0.955 1.11 -0.00535 0.109 0.961 0.01728 0.995 0.803 1.23 0.07 0.108 0.517 0.2864 1.07 0.868 1.33 -0.0395 0.109 0.718 0.1441 0.961 0.776 1.19 PRS_PLINK_2.51188643150958e.06 FALSE 440.1 Atherosclerosis of renal artery Both 81 317 8 circulatory system red 317, 81 80, 18 79, 18 79, 30 79, 15 0.0124 0.115 0.914 0.03887 1.01 0.808 1.27 0.0381 0.381 0.92 0.03606 1.04 0.492 2.19 0.49 0.339 0.148 0.8289 1.63 0.84 3.17 -0.134 0.387 0.728 0.1379 0.874 0.41 1.87 PRS_PLINK_2.51188643150958e.06 FALSE 440.2 Atherosclerosis of the extremities Both 647 1831 8 circulatory system red 1831, 647 458, 167 458, 155 457, 184 458, 141 -0.0175 0.0451 0.699 0.1555 0.983 0.899 1.07 -0.0656 0.131 0.618 0.2092 0.937 0.724 1.21 0.117 0.127 0.359 0.4455 1.12 0.876 1.44 -0.195 0.134 0.147 0.8341 0.823 0.633 1.07 PRS_PLINK_2.51188643150958e.06 FALSE 440.21 Atherosclerosis of native arteries of the extremities with ulceration or gangrene Both 126 373 8 circulatory system red 373, 126 94, 41 93, 26 93, 28 93, 31 -0.121 0.0944 0.201 0.6975 0.886 0.737 1.07 -0.401 0.298 0.179 0.7473 0.67 0.373 1.2 -0.262 0.291 0.367 0.4357 0.769 0.435 1.36 -0.225 0.287 0.433 0.3637 0.799 0.455 1.4 PRS_PLINK_2.51188643150958e.06 FALSE 440.22 Atherosclerosis of native arteries of the extremities with intermittent claudication Both 470 1371 8 circulatory system red 1371, 470 343, 124 343, 123 342, 122 343, 101 -0.0484 0.0541 0.371 0.4306 0.953 0.857 1.06 0.0158 0.15 0.916 0.03805 1.02 0.757 1.36 -0.00946 0.15 0.95 0.02235 0.991 0.738 1.33 -0.231 0.156 0.14 0.8554 0.794 0.584 1.08 PRS_PLINK_2.51188643150958e.06 FALSE 440.9 Atherosclerosis of aorta Both 296 1101 8 circulatory system red 1101, 296 276, 66 275, 80 275, 67 275, 83 0.0794 0.0708 0.262 0.5811 1.08 0.942 1.24 0.214 0.189 0.26 0.5854 1.24 0.854 1.79 0.0409 0.196 0.835 0.0785 1.04 0.71 1.53 0.226 0.187 0.227 0.6435 1.25 0.868 1.81 PRS_PLINK_2.51188643150958e.06 FALSE 441 Vascular insufficiency of intestine Both 221 765 8 circulatory system red 765, 221 192, 64 191, 54 191, 55 191, 48 -0.0439 0.0785 0.576 0.2396 0.957 0.821 1.12 -0.125 0.212 0.556 0.255 0.883 0.582 1.34 -0.104 0.215 0.63 0.2009 0.902 0.592 1.37 -0.268 0.221 0.224 0.6492 0.765 0.496 1.18 PRS_PLINK_2.51188643150958e.06 FALSE 441.1 Acute vascular insufficiency of intestine Both 111 361 8 circulatory system red 361, 111 91, 47 90, 18 90, 19 90, 27 -0.168 0.116 0.149 0.8263 0.846 0.673 1.06 -0.964 0.32 0.00263 2.58 0.381 0.204 0.715 -0.862 0.316 0.00639 2.195 0.422 0.227 0.785 -0.526 0.294 0.0741 1.13 0.591 0.332 1.05 PRS_PLINK_2.51188643150958e.06 FALSE 441.2 Chronic vascular insufficiency of intestine Both 66 245 8 circulatory system red 245, 66 62, 20 61, 17 61, 19 61, 10 -0.0232 0.133 0.861 0.06503 0.977 0.753 1.27 -0.114 0.379 0.764 0.1167 0.892 0.424 1.88 -0.0439 0.395 0.912 0.04018 0.957 0.441 2.08 -0.737 0.432 0.0879 1.056 0.479 0.205 1.12 PRS_PLINK_2.51188643150958e.06 FALSE 442 Other aneurysm Both 742 2759 8 circulatory system red 2759, 742 690, 198 690, 196 689, 180 690, 167 -0.024 0.0422 0.57 0.2444 0.976 0.899 1.06 0.00537 0.117 0.963 0.01627 1.01 0.8 1.26 -0.0483 0.119 0.685 0.1643 0.953 0.755 1.2 -0.178 0.121 0.139 0.8569 0.837 0.661 1.06 PRS_PLINK_2.51188643150958e.06 FALSE 442.1 Aortic aneurysm Both 574 2094 8 circulatory system red 2094, 574 524, 154 523, 146 523, 146 524, 127 -0.0308 0.0468 0.51 0.2928 0.97 0.885 1.06 -0.0421 0.133 0.752 0.1241 0.959 0.739 1.24 -0.0196 0.133 0.883 0.05396 0.981 0.755 1.27 -0.201 0.137 0.143 0.8458 0.818 0.625 1.07 PRS_PLINK_2.51188643150958e.06 FALSE 442.11 Abdominal aortic aneurysm Both 339 1353 8 circulatory system red 1353, 339 339, 91 338, 90 338, 84 338, 74 -0.0287 0.0591 0.627 0.2025 0.972 0.865 1.09 -0.0397 0.169 0.814 0.08939 0.961 0.69 1.34 -0.0696 0.172 0.685 0.1643 0.933 0.666 1.31 -0.222 0.177 0.21 0.6783 0.801 0.566 1.13 PRS_PLINK_2.51188643150958e.06 FALSE 442.2 Aneurysm of iliac artery Both 50 253 8 circulatory system red 253, 50 64, 12 63, 13 63, 17 63, 8 0.0288 0.163 0.86 0.06569 1.03 0.748 1.42 -0.0392 0.455 0.931 0.03089 0.962 0.394 2.35 0.376 0.424 0.375 0.4254 1.46 0.634 3.34 -0.33 0.503 0.512 0.2908 0.719 0.268 1.93 PRS_PLINK_2.51188643150958e.06 TRUE 442.3 Aneurysm of artery of lower extremity Both 50 209 8 circulatory system red 209, 50 53, 11 52, 10 52, 16 52, 13 0.13 0.164 0.428 0.3689 1.14 0.826 1.57 0.0246 0.484 0.959 0.01799 1.02 0.397 2.65 0.338 0.441 0.443 0.3538 1.4 0.591 3.33 0.0656 0.45 0.884 0.05345 1.07 0.442 2.58 PRS_PLINK_2.51188643150958e.06 TRUE 442.4 Arterial dissection Both 53 243 8 circulatory system red 243, 53 61, 13 61, 16 60, 10 61, 14 0.199 0.177 0.26 0.5846 1.22 0.863 1.73 0.137 0.418 0.744 0.1286 1.15 0.505 2.6 -0.21 0.447 0.639 0.1948 0.811 0.338 1.95 0.182 0.449 0.685 0.1642 1.2 0.497 2.89 PRS_PLINK_2.51188643150958e.06 FALSE 442.8 Aneurysm of other specified artery Both 115 535 8 circulatory system red 535, 115 134, 23 134, 33 133, 26 134, 33 0.256 0.119 0.0305 1.516 1.29 1.02 1.63 0.352 0.297 0.236 0.6264 1.42 0.794 2.55 0.253 0.313 0.418 0.3786 1.29 0.698 2.38 0.378 0.298 0.204 0.6899 1.46 0.814 2.62 PRS_PLINK_2.51188643150958e.06 FALSE 443 Peripheral vascular disease Both 1157 3330 8 circulatory system red 3330, 1157 833, 295 832, 289 832, 312 833, 261 0.0154 0.0351 0.66 0.1804 1.02 0.948 1.09 0.0132 0.0981 0.893 0.04922 1.01 0.836 1.23 0.0745 0.0967 0.441 0.3552 1.08 0.891 1.3 -0.122 0.0996 0.219 0.6597 0.885 0.728 1.08 PRS_PLINK_2.51188643150958e.06 FALSE 443.1 Raynaud's syndrome Both 302 1067 8 circulatory system red 1067, 302 267, 68 267, 81 266, 84 267, 69 0.0777 0.071 0.274 0.5621 1.08 0.94 1.24 0.172 0.186 0.355 0.4495 1.19 0.824 1.71 0.2 0.185 0.279 0.554 1.22 0.85 1.76 0.0158 0.192 0.934 0.02949 1.02 0.698 1.48 PRS_PLINK_2.51188643150958e.06 FALSE 443.7 Peripheral angiopathy in diseases classified elsewhere Both 110 355 8 circulatory system red 355, 110 89, 41 89, 21 88, 29 89, 19 -0.156 0.1 0.119 0.9256 0.855 0.703 1.04 -0.558 0.317 0.0782 1.107 0.572 0.307 1.07 -0.28 0.296 0.344 0.4638 0.756 0.423 1.35 -0.596 0.323 0.0646 1.19 0.551 0.293 1.04 PRS_PLINK_2.51188643150958e.06 FALSE 443.8 Other specified peripheral vascular diseases Both 947 2972 8 circulatory system red 2972, 947 743, 245 743, 233 743, 255 743, 214 0.0091 0.039 0.815 0.08864 1.01 0.935 1.09 -0.0192 0.107 0.857 0.06699 0.981 0.796 1.21 0.0545 0.105 0.603 0.2197 1.06 0.86 1.3 -0.128 0.108 0.236 0.6275 0.88 0.712 1.09 PRS_PLINK_2.51188643150958e.06 FALSE 443.9 Peripheral vascular disease, unspecified Both 866 2533 8 circulatory system red 2533, 866 634, 222 633, 218 633, 231 633, 195 0.000525 0.041 0.99 0.004459 1 0.923 1.08 0.0263 0.113 0.816 0.08837 1.03 0.823 1.28 0.07 0.112 0.531 0.2753 1.07 0.862 1.33 -0.118 0.115 0.306 0.5139 0.889 0.709 1.11 PRS_PLINK_2.51188643150958e.06 FALSE 444 Arterial embolism and thrombosis Both 290 1116 8 circulatory system red 1116, 290 279, 82 279, 66 279, 82 279, 60 -0.00998 0.0704 0.887 0.05194 0.99 0.862 1.14 -0.177 0.188 0.346 0.4612 0.838 0.58 1.21 0.0051 0.18 0.977 0.009908 1.01 0.706 1.43 -0.323 0.194 0.0949 1.023 0.724 0.495 1.06 PRS_PLINK_2.51188643150958e.06 FALSE 444.1 Arterial embolism and thrombosis of lower extremity artery Both 108 440 8 circulatory system red 440, 108 110, 33 110, 25 110, 29 110, 21 -0.119 0.118 0.315 0.5017 0.888 0.704 1.12 -0.247 0.304 0.416 0.3808 0.781 0.431 1.42 -0.157 0.293 0.593 0.227 0.855 0.481 1.52 -0.45 0.315 0.154 0.8127 0.638 0.344 1.18 PRS_PLINK_2.51188643150958e.06 FALSE 444.2 Embolism and thrombosis of abdominal aorta Both 45 191 8 circulatory system red 191, 45 48, 17 48, 12 47, 11 48, 5 -0.213 0.18 0.237 0.6248 0.808 0.568 1.15 -0.282 0.436 0.518 0.2859 0.754 0.321 1.77 -0.448 0.449 0.319 0.4967 0.639 0.265 1.54 -1.18 0.537 0.0283 1.549 0.308 0.108 0.882 PRS_PLINK_2.51188643150958e.06 TRUE 446 Polyarteritis nodosa and allied conditions Both 214 626 8 circulatory system red 626, 214 157, 59 156, 44 156, 59 157, 52 0.0381 0.083 0.646 0.1896 1.04 0.883 1.22 -0.216 0.235 0.358 0.4465 0.806 0.509 1.28 0.058 0.219 0.791 0.1017 1.06 0.69 1.63 -0.0966 0.225 0.668 0.1755 0.908 0.584 1.41 PRS_PLINK_2.51188643150958e.06 FALSE 446.4 Wegener's granulomatosis Both 44 146 8 circulatory system red 146, 44 37, 14 36, 9 36, 15 37, 6 -0.19 0.16 0.235 0.6285 0.827 0.605 1.13 -0.19 0.544 0.727 0.1385 0.827 0.285 2.4 0.16 0.466 0.731 0.1363 1.17 0.471 2.93 -0.682 0.577 0.237 0.6255 0.505 0.163 1.57 PRS_PLINK_2.51188643150958e.06 TRUE 446.5 Giant cell arteritis Both 40 108 8 circulatory system red 108, 40 27, 14 27, 5 27, 14 27, 7 -0.123 0.215 0.569 0.2452 0.884 0.58 1.35 -0.81 0.606 0.181 0.7414 0.445 0.136 1.46 0.101 0.506 0.842 0.07476 1.11 0.41 2.98 -0.555 0.566 0.327 0.4861 0.574 0.189 1.74 PRS_PLINK_2.51188643150958e.06 TRUE 446.9 Arteritis NOS Both 154 396 8 circulatory system red 396, 154 99, 46 99, 38 99, 38 99, 32 0.0222 0.104 0.831 0.08051 1.02 0.834 1.25 -0.11 0.269 0.681 0.1666 0.896 0.529 1.52 -0.21 0.269 0.435 0.3616 0.81 0.478 1.37 -0.368 0.276 0.181 0.7413 0.692 0.403 1.19 PRS_PLINK_2.51188643150958e.06 FALSE 447 Other disorders of arteries and arterioles Both 900 2956 8 circulatory system red 2956, 900 739, 236 739, 229 739, 238 739, 197 -0.0244 0.038 0.521 0.2832 0.976 0.906 1.05 -0.013 0.107 0.904 0.04393 0.987 0.8 1.22 0.0361 0.107 0.736 0.1331 1.04 0.84 1.28 -0.182 0.111 0.101 0.9946 0.834 0.671 1.04 PRS_PLINK_2.51188643150958e.06 FALSE 447.1 Stricture of artery Both 174 672 8 circulatory system red 672, 174 168, 47 168, 39 168, 53 168, 35 -0.0809 0.0869 0.352 0.4539 0.922 0.778 1.09 -0.19 0.245 0.439 0.3571 0.827 0.511 1.34 0.149 0.23 0.517 0.2867 1.16 0.74 1.82 -0.263 0.253 0.3 0.5234 0.769 0.468 1.26 PRS_PLINK_2.51188643150958e.06 FALSE 447.7 Aortic ectasia Both 240 1005 8 circulatory system red 1005, 240 252, 50 251, 67 251, 71 251, 52 -0.0145 0.0699 0.836 0.078 0.986 0.859 1.13 0.283 0.208 0.174 0.7583 1.33 0.882 2 0.382 0.206 0.0632 1.199 1.47 0.979 2.19 0.0509 0.218 0.815 0.08858 1.05 0.686 1.61 PRS_PLINK_2.51188643150958e.06 FALSE 448 Disease of capillaries Both 359 1759 8 circulatory system red 1759, 359 440, 89 440, 88 439, 88 440, 94 0.00635 0.0556 0.909 0.04142 1.01 0.903 1.12 0.0213 0.165 0.897 0.04702 1.02 0.739 1.41 0.0105 0.166 0.95 0.02249 1.01 0.73 1.4 0.0553 0.163 0.734 0.134 1.06 0.768 1.46 PRS_PLINK_2.51188643150958e.06 FALSE 450 Noninfectious disorders of lymphatic channels Both 551 3668 8 circulatory system red 3668, 551 917, 134 917, 141 917, 140 917, 136 0.024 0.0471 0.611 0.2142 1.02 0.934 1.12 0.0482 0.129 0.709 0.1495 1.05 0.815 1.35 0.0572 0.13 0.659 0.1812 1.06 0.821 1.36 0.0224 0.13 0.863 0.06374 1.02 0.792 1.32 PRS_PLINK_2.51188643150958e.06 FALSE 451 Phlebitis and thrombophlebitis Both 269 832 8 circulatory system red 832, 269 208, 72 208, 56 208, 70 208, 71 0.0747 0.0767 0.33 0.4811 1.08 0.927 1.25 -0.262 0.205 0.202 0.6955 0.77 0.515 1.15 -0.0112 0.198 0.955 0.02008 0.989 0.671 1.46 0.0268 0.198 0.893 0.04933 1.03 0.696 1.52 PRS_PLINK_2.51188643150958e.06 FALSE 451.2 Phlebitis and thrombophlebitis of lower extremities Both 102 290 8 circulatory system red 290, 102 73, 27 72, 18 72, 25 73, 32 0.184 0.144 0.201 0.6973 1.2 0.907 1.59 -0.326 0.352 0.355 0.4494 0.722 0.362 1.44 0.000993 0.328 0.998 0.001049 1 0.526 1.91 0.201 0.321 0.532 0.274 1.22 0.651 2.29 PRS_PLINK_2.51188643150958e.06 FALSE 452 Other venous embolism and thrombosis Both 1439 3142 8 circulatory system red 3142, 1439 786, 376 785, 342 785, 361 786, 360 -0.00307 0.0326 0.925 0.03394 0.997 0.935 1.06 -0.106 0.092 0.249 0.6045 0.899 0.751 1.08 -0.046 0.0915 0.615 0.211 0.955 0.798 1.14 -0.0405 0.0914 0.658 0.1819 0.96 0.803 1.15 PRS_PLINK_2.51188643150958e.06 FALSE 452.1 Iatrogenic pulmonary embolism and infarction Both 130 305 8 circulatory system red 305, 130 77, 34 76, 23 76, 41 76, 32 -0.0151 0.115 0.895 0.04817 0.985 0.787 1.23 -0.404 0.328 0.217 0.6635 0.667 0.351 1.27 0.145 0.294 0.621 0.2069 1.16 0.65 2.06 -0.076 0.309 0.806 0.09374 0.927 0.506 1.7 PRS_PLINK_2.51188643150958e.06 FALSE 452.2 Deep vein thrombosis [DVT] Both 966 2874 8 circulatory system red 2874, 966 719, 255 718, 223 718, 245 719, 243 -0.00748 0.0374 0.842 0.07485 0.993 0.922 1.07 -0.153 0.107 0.153 0.8146 0.858 0.696 1.06 -0.0392 0.105 0.709 0.1492 0.962 0.782 1.18 -0.0493 0.105 0.64 0.1941 0.952 0.774 1.17 PRS_PLINK_2.51188643150958e.06 FALSE 452.8 Postphlebitic syndrome Both 54 143 8 circulatory system red 143, 54 36, 15 36, 5 35, 14 36, 20 0.212 0.178 0.233 0.6322 1.24 0.872 1.75 -0.899 0.552 0.103 0.9861 0.407 0.138 1.2 -0.191 0.48 0.692 0.1602 0.826 0.322 2.12 0.478 0.448 0.286 0.5443 1.61 0.671 3.88 PRS_PLINK_2.51188643150958e.06 FALSE 453 Chronic venous hypertension Both 70 273 8 circulatory system red 273, 70 69, 25 68, 15 68, 14 68, 16 -0.235 0.123 0.0571 1.243 0.791 0.621 1.01 -0.349 0.374 0.35 0.4563 0.705 0.339 1.47 -0.68 0.394 0.0843 1.074 0.506 0.234 1.1 -0.325 0.369 0.379 0.4208 0.723 0.351 1.49 PRS_PLINK_2.51188643150958e.06 FALSE 454 Varicose veins Both 899 2707 8 circulatory system red 2707, 899 677, 222 677, 223 676, 229 677, 225 -0.0106 0.0397 0.79 0.1024 0.989 0.915 1.07 -0.0268 0.111 0.81 0.09156 0.974 0.783 1.21 0.0288 0.111 0.795 0.09975 1.03 0.828 1.28 0.0159 0.112 0.887 0.05222 1.02 0.816 1.27 PRS_PLINK_2.51188643150958e.06 FALSE 454.1 Varicose veins of lower extremity Both 834 2448 8 circulatory system red 2448, 834 612, 215 612, 191 612, 214 612, 214 -0.00499 0.0415 0.904 0.04368 0.995 0.917 1.08 -0.145 0.116 0.214 0.6704 0.865 0.689 1.09 -7.32e-05 0.114 0.999 0.0002222 1 0.799 1.25 0.00335 0.115 0.977 0.01022 1 0.801 1.26 PRS_PLINK_2.51188643150958e.06 FALSE 454.11 Varicose veins of lower extremity, symptomtic Both 563 1774 8 circulatory system red 1774, 563 444, 141 443, 126 443, 158 444, 138 -0.0296 0.0507 0.559 0.2522 0.971 0.879 1.07 -0.119 0.141 0.402 0.3957 0.888 0.673 1.17 0.139 0.135 0.304 0.517 1.15 0.882 1.5 -0.00767 0.14 0.956 0.01946 0.992 0.755 1.3 PRS_PLINK_2.51188643150958e.06 FALSE 455 Hemorrhoids Both 2061 3199 8 circulatory system red 3199, 2061 800, 500 800, 517 799, 499 800, 545 0.0102 0.0292 0.728 0.1379 1.01 0.954 1.07 0.0135 0.0827 0.87 0.06051 1.01 0.862 1.19 0.000345 0.0831 0.997 0.001443 1 0.85 1.18 0.105 0.0826 0.203 0.6924 1.11 0.945 1.31 PRS_PLINK_2.51188643150958e.06 FALSE 456 Chronic venous insufficiency [CVI] Both 1204 2800 8 circulatory system red 2800, 1204 700, 315 700, 276 700, 302 700, 311 0.0146 0.036 0.686 0.1639 1.01 0.946 1.09 -0.16 0.101 0.112 0.9517 0.852 0.699 1.04 -0.0363 0.0994 0.715 0.1459 0.964 0.794 1.17 0.0188 0.0989 0.849 0.07092 1.02 0.839 1.24 PRS_PLINK_2.51188643150958e.06 FALSE 457 Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin Both 664 1692 8 circulatory system red 1692, 664 423, 180 423, 151 423, 155 423, 177 -0.00934 0.0473 0.844 0.0739 0.991 0.903 1.09 -0.17 0.132 0.195 0.7104 0.843 0.652 1.09 -0.156 0.131 0.233 0.6318 0.856 0.662 1.11 -0.059 0.129 0.648 0.1886 0.943 0.732 1.21 PRS_PLINK_2.51188643150958e.06 FALSE 457.2 Encounter for long-term (current) use of antiplatelets/antithrombotics Both 123 357 8 circulatory system red 357, 123 90, 30 89, 28 89, 27 89, 37 0.0517 0.11 0.64 0.1939 1.05 0.848 1.31 -0.0348 0.304 0.909 0.04151 0.966 0.532 1.75 -0.207 0.316 0.513 0.2901 0.813 0.437 1.51 0.236 0.296 0.424 0.3728 1.27 0.71 2.26 PRS_PLINK_2.51188643150958e.06 FALSE 457.3 Encounter for long-term (current) use of aspirin Both 614 1628 8 circulatory system red 1628, 614 407, 166 407, 143 407, 146 407, 158 -0.0299 0.0488 0.54 0.2676 0.971 0.882 1.07 -0.137 0.135 0.31 0.5086 0.872 0.668 1.14 -0.14 0.135 0.299 0.5245 0.869 0.667 1.13 -0.0894 0.134 0.505 0.2971 0.914 0.703 1.19 PRS_PLINK_2.51188643150958e.06 FALSE 458 Hypotension Both 1851 3954 8 circulatory system red 3954, 1851 989, 494 988, 412 988, 499 989, 445 -0.0114 0.0285 0.689 0.1617 0.989 0.935 1.05 -0.171 0.0826 0.0379 1.421 0.842 0.717 0.99 0.0123 0.0799 0.878 0.05665 1.01 0.866 1.18 -0.116 0.0812 0.153 0.8146 0.89 0.759 1.04 PRS_PLINK_2.51188643150958e.06 FALSE 458.1 Orthostatic hypotension Both 651 1664 8 circulatory system red 1664, 651 416, 178 416, 146 416, 191 416, 136 -0.0875 0.0455 0.0543 1.265 0.916 0.838 1 -0.171 0.132 0.196 0.7086 0.843 0.65 1.09 0.0719 0.126 0.569 0.2452 1.07 0.839 1.38 -0.275 0.134 0.0411 1.386 0.76 0.584 0.989 PRS_PLINK_2.51188643150958e.06 FALSE 458.2 Iatrogenic hypotension Both 391 1377 8 circulatory system red 1377, 391 345, 108 344, 95 344, 93 344, 95 -0.012 0.0581 0.837 0.07745 0.988 0.882 1.11 -0.111 0.162 0.495 0.3056 0.895 0.652 1.23 -0.132 0.164 0.42 0.3768 0.876 0.636 1.21 -0.158 0.163 0.33 0.4815 0.854 0.621 1.17 PRS_PLINK_2.51188643150958e.06 FALSE 458.9 Hypotension NOS Both 1703 3841 8 circulatory system red 3841, 1703 961, 453 960, 381 960, 465 960, 403 -0.0241 0.0293 0.41 0.3869 0.976 0.922 1.03 -0.16 0.085 0.0603 1.22 0.852 0.722 1.01 0.0285 0.0822 0.728 0.1376 1.03 0.876 1.21 -0.129 0.0841 0.125 0.9033 0.879 0.745 1.04 PRS_PLINK_2.51188643150958e.06 FALSE 459 Other disorders of circulatory system Both 2304 4179 8 circulatory system red 4179, 2304 1045, 609 1045, 526 1044, 618 1045, 550 0.00876 0.027 0.746 0.1272 1.01 0.957 1.06 -0.137 0.0766 0.0741 1.13 0.872 0.75 1.01 0.0275 0.0752 0.715 0.1459 1.03 0.887 1.19 -0.0946 0.076 0.214 0.6705 0.91 0.784 1.06 PRS_PLINK_2.51188643150958e.06 FALSE 459.1 Hemorrhage NOS Both 320 1051 8 circulatory system red 1051, 320 263, 89 263, 51 262, 101 263, 79 -0.0177 0.0634 0.78 0.1078 0.982 0.868 1.11 -0.528 0.198 0.0078 2.108 0.59 0.4 0.87 0.116 0.172 0.498 0.3028 1.12 0.802 1.57 -0.102 0.18 0.573 0.2421 0.903 0.635 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 459.7 Blood vessel replaced Both 343 1550 8 circulatory system red 1550, 343 388, 103 387, 72 387, 85 388, 83 -0.0405 0.0594 0.495 0.3052 0.96 0.855 1.08 -0.35 0.17 0.0389 1.411 0.704 0.505 0.982 -0.17 0.163 0.297 0.5265 0.844 0.612 1.16 -0.224 0.164 0.174 0.7598 0.8 0.579 1.1 PRS_PLINK_2.51188643150958e.06 FALSE 459.9 Circulatory disease NEC Both 2017 4084 8 circulatory system red 4084, 2017 1021, 537 1021, 471 1021, 536 1021, 472 0.00403 0.0285 0.888 0.05175 1 0.949 1.06 -0.127 0.0801 0.114 0.9447 0.881 0.753 1.03 0.00491 0.0791 0.95 0.02205 1 0.861 1.17 -0.129 0.08 0.108 0.9667 0.879 0.752 1.03 PRS_PLINK_2.51188643150958e.06 FALSE 464 Acute sinusitis Both 1707 3524 9 respiratory coral4 3524, 1707 881, 431 881, 413 881, 439 881, 424 0.0151 0.0295 0.609 0.2155 1.02 0.958 1.08 -0.0716 0.0856 0.403 0.395 0.931 0.787 1.1 0.000202 0.0848 0.998 0.0008252 1 0.847 1.18 -0.0218 0.0853 0.799 0.0977 0.978 0.828 1.16 PRS_PLINK_2.51188643150958e.06 FALSE 465 Acute upper respiratory infections of multiple or unspecified sites Both 3210 3882 9 respiratory coral4 3882, 3210 970, 766 970, 841 970, 789 971, 814 0.0452 0.0244 0.0633 1.199 1.05 0.997 1.1 0.0924 0.069 0.181 0.7434 1.1 0.958 1.26 0.0465 0.0697 0.505 0.2967 1.05 0.914 1.2 0.0716 0.0696 0.304 0.5178 1.07 0.937 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 465.2 Acute pharyngitis Both 1742 3446 9 respiratory coral4 3446, 1742 862, 399 861, 456 861, 459 862, 428 0.0802 0.031 0.0098 2.009 1.08 1.02 1.15 0.132 0.0854 0.123 0.9094 1.14 0.965 1.35 0.156 0.0852 0.0676 1.17 1.17 0.989 1.38 0.08 0.0867 0.356 0.4486 1.08 0.914 1.28 PRS_PLINK_2.51188643150958e.06 FALSE 465.4 Acute laryngitis and tracheitis Both 154 568 9 respiratory coral4 568, 154 142, 44 142, 33 142, 38 142, 39 0.0158 0.0985 0.873 0.05907 1.02 0.837 1.23 -0.39 0.268 0.146 0.8357 0.677 0.4 1.15 -0.197 0.254 0.438 0.3587 0.821 0.499 1.35 -0.0756 0.257 0.769 0.1142 0.927 0.56 1.53 PRS_PLINK_2.51188643150958e.06 FALSE 470 Septal Deviations/Turbinate Hypertrophy Both 421 1767 9 respiratory coral4 1767, 421 442, 113 442, 117 441, 93 442, 98 -0.06 0.0506 0.236 0.6273 0.942 0.853 1.04 0.0301 0.15 0.84 0.07554 1.03 0.769 1.38 -0.19 0.157 0.225 0.6475 0.827 0.609 1.12 -0.141 0.155 0.364 0.4395 0.869 0.641 1.18 PRS_PLINK_2.51188643150958e.06 FALSE 471 Nasal polyps Both 122 683 9 respiratory coral4 683, 122 171, 24 171, 39 170, 31 171, 28 0.0153 0.102 0.881 0.05516 1.02 0.831 1.24 0.5 0.278 0.0718 1.144 1.65 0.957 2.84 0.309 0.292 0.289 0.5385 1.36 0.769 2.42 0.224 0.295 0.449 0.3479 1.25 0.701 2.23 PRS_PLINK_2.51188643150958e.06 FALSE 472 Chronic pharyngitis and nasopharyngitis Both 667 1905 9 respiratory coral4 1905, 667 477, 197 476, 166 476, 161 476, 143 -0.0523 0.043 0.224 0.6496 0.949 0.872 1.03 -0.145 0.125 0.247 0.6078 0.865 0.677 1.11 -0.185 0.126 0.141 0.8513 0.831 0.649 1.06 -0.29 0.129 0.0251 1.601 0.748 0.581 0.964 PRS_PLINK_2.51188643150958e.06 FALSE 473 Diseases of the larynx and vocal cords Both 831 2715 9 respiratory coral4 2715, 831 679, 208 679, 221 678, 193 679, 209 0.00177 0.0397 0.964 0.01575 1 0.927 1.08 0.0829 0.112 0.459 0.3383 1.09 0.872 1.35 -0.0704 0.116 0.542 0.2657 0.932 0.743 1.17 0.0078 0.114 0.945 0.02443 1.01 0.806 1.26 PRS_PLINK_2.51188643150958e.06 FALSE 473.1 Chronic laryngitis Both 21 108 9 respiratory coral4 108, 21 27, 3 27, 2 27, 10 27, 6 0.298 0.256 0.244 0.6133 1.35 0.816 2.22 -0.00924 0.928 0.992 0.003465 0.991 0.161 6.11 0.909 0.707 0.198 0.7026 2.48 0.621 9.91 0.404 0.801 0.614 0.2117 1.5 0.312 7.2 PRS_PLINK_2.51188643150958e.06 TRUE 473.3 Paralysis/spasm of vocal cords or larynx Both 149 689 9 respiratory coral4 689, 149 173, 35 172, 47 172, 29 172, 38 0.0881 0.0924 0.34 0.4682 1.09 0.911 1.31 0.339 0.252 0.178 0.7492 1.4 0.857 2.3 -0.0805 0.274 0.769 0.1139 0.923 0.539 1.58 0.111 0.26 0.67 0.1737 1.12 0.671 1.86 PRS_PLINK_2.51188643150958e.06 FALSE 473.4 Voice disturbance Both 671 2391 9 respiratory coral4 2391, 671 598, 167 598, 171 597, 162 598, 171 0.0126 0.0435 0.772 0.1124 1.01 0.93 1.1 0.0436 0.125 0.726 0.139 1.04 0.818 1.33 -0.0198 0.126 0.875 0.05789 0.98 0.765 1.26 0.0395 0.125 0.752 0.124 1.04 0.815 1.33 PRS_PLINK_2.51188643150958e.06 FALSE 474 Acute and chronic tonsillitis Both 185 745 9 respiratory coral4 745, 185 187, 39 186, 51 186, 47 186, 48 0.133 0.0862 0.122 0.9135 1.14 0.965 1.35 0.245 0.237 0.302 0.5205 1.28 0.803 2.03 0.19 0.247 0.44 0.3562 1.21 0.746 1.96 0.299 0.246 0.224 0.6506 1.35 0.833 2.18 PRS_PLINK_2.51188643150958e.06 FALSE 474.1 Acute tonsillitis Both 63 267 9 respiratory coral4 267, 63 67, 11 67, 21 66, 17 67, 14 0.214 0.155 0.168 0.7745 1.24 0.914 1.68 0.617 0.409 0.131 0.8831 1.85 0.832 4.13 0.368 0.424 0.385 0.4146 1.45 0.63 3.32 0.195 0.45 0.665 0.1774 1.22 0.503 2.94 PRS_PLINK_2.51188643150958e.06 FALSE 474.2 Chronic tonsillitis and adenoiditis Both 140 590 9 respiratory coral4 590, 140 148, 27 147, 43 147, 34 148, 36 0.106 0.0943 0.262 0.5815 1.11 0.924 1.34 0.403 0.272 0.138 0.8606 1.5 0.879 2.55 0.195 0.291 0.503 0.2983 1.21 0.687 2.15 0.362 0.286 0.207 0.685 1.44 0.819 2.52 PRS_PLINK_2.51188643150958e.06 FALSE 475 Chronic sinusitis Both 1347 2906 9 respiratory coral4 2906, 1347 727, 315 726, 395 726, 334 727, 302 0.00216 0.0329 0.948 0.02334 1 0.94 1.07 0.228 0.0933 0.0145 1.839 1.26 1.05 1.51 0.0696 0.0962 0.47 0.3282 1.07 0.888 1.29 -0.0205 0.0975 0.833 0.07917 0.98 0.809 1.19 PRS_PLINK_2.51188643150958e.06 FALSE 475.9 Postnasal drip Both 333 1065 9 respiratory coral4 1065, 333 267, 74 266, 107 266, 82 266, 69 -0.0259 0.0591 0.661 0.18 0.974 0.868 1.09 0.458 0.179 0.0108 1.968 1.58 1.11 2.25 0.165 0.186 0.376 0.4251 1.18 0.819 1.7 -0.0318 0.191 0.868 0.06151 0.969 0.666 1.41 PRS_PLINK_2.51188643150958e.06 FALSE 476 Allergic rhinitis Both 3241 2928 9 respiratory coral4 2928, 3241 732, 749 732, 868 732, 815 732, 809 0.0463 0.0262 0.0772 1.112 1.05 0.995 1.1 0.156 0.0736 0.0338 1.471 1.17 1.01 1.35 0.0994 0.0743 0.181 0.7426 1.1 0.955 1.28 0.0941 0.0743 0.206 0.6871 1.1 0.95 1.27 PRS_PLINK_2.51188643150958e.06 FALSE 477 Epistaxis or throat hemorrhage Both 406 1221 9 respiratory coral4 1221, 406 306, 109 305, 80 305, 118 305, 99 0.00644 0.0576 0.911 0.0405 1.01 0.899 1.13 -0.259 0.171 0.129 0.8888 0.772 0.552 1.08 0.112 0.157 0.475 0.3236 1.12 0.823 1.52 -0.0679 0.162 0.675 0.1706 0.934 0.68 1.28 PRS_PLINK_2.51188643150958e.06 FALSE 478 Throat pain Both 144 426 9 respiratory coral4 426, 144 107, 42 106, 38 106, 28 107, 36 -0.0163 0.0936 0.861 0.06475 0.984 0.819 1.18 -0.112 0.267 0.675 0.1705 0.894 0.53 1.51 -0.367 0.284 0.196 0.7074 0.693 0.397 1.21 -0.136 0.272 0.617 0.2094 0.873 0.513 1.49 PRS_PLINK_2.51188643150958e.06 FALSE 479 Other upper respiratory disease Both 1732 2922 9 respiratory coral4 2922, 1732 731, 440 730, 451 730, 420 731, 421 -0.0131 0.0295 0.657 0.1827 0.987 0.931 1.05 0.0311 0.086 0.718 0.144 1.03 0.872 1.22 -0.0314 0.0871 0.719 0.1435 0.969 0.817 1.15 -0.0355 0.087 0.683 0.1657 0.965 0.814 1.14 PRS_PLINK_2.51188643150958e.06 FALSE 480 Pneumonia Both 2111 4309 9 respiratory coral4 4309, 2111 1078, 539 1077, 531 1077, 544 1077, 496 -0.0306 0.0265 0.249 0.6039 0.97 0.921 1.02 -0.0271 0.0756 0.72 0.1424 0.973 0.839 1.13 -0.0056 0.0754 0.941 0.02651 0.994 0.858 1.15 -0.0898 0.0767 0.242 0.6168 0.914 0.787 1.06 PRS_PLINK_2.51188643150958e.06 FALSE 480.1 Bacterial pneumonia Both 488 1407 9 respiratory coral4 1407, 488 352, 123 352, 107 351, 141 352, 117 -0.0165 0.0525 0.753 0.1231 0.984 0.887 1.09 -0.145 0.153 0.345 0.4627 0.865 0.64 1.17 0.134 0.146 0.36 0.4443 1.14 0.859 1.52 -0.0523 0.152 0.73 0.1365 0.949 0.705 1.28 PRS_PLINK_2.51188643150958e.06 FALSE 480.11 Pneumococcal pneumonia Both 260 672 9 respiratory coral4 672, 260 168, 55 168, 67 168, 76 168, 62 0.0793 0.0732 0.279 0.5544 1.08 0.938 1.25 0.199 0.214 0.353 0.4524 1.22 0.802 1.86 0.355 0.213 0.0948 1.023 1.43 0.94 2.16 0.0905 0.218 0.678 0.169 1.09 0.714 1.68 PRS_PLINK_2.51188643150958e.06 FALSE 480.12 Pseudomonal pneumonia Both 53 160 9 respiratory coral4 160, 53 40, 17 40, 9 40, 11 40, 16 -0.106 0.147 0.47 0.3277 0.899 0.674 1.2 -0.714 0.483 0.139 0.8574 0.489 0.19 1.26 -0.47 0.464 0.311 0.5066 0.625 0.252 1.55 -0.0713 0.43 0.868 0.06134 0.931 0.401 2.16 PRS_PLINK_2.51188643150958e.06 FALSE 480.13 MRSA pneumonia Both 52 126 9 respiratory coral4 126, 52 32, 15 31, 10 31, 18 32, 9 -0.161 0.194 0.408 0.3896 0.851 0.582 1.25 -0.478 0.505 0.345 0.4628 0.62 0.23 1.67 0.285 0.462 0.537 0.2696 1.33 0.538 3.29 -0.445 0.515 0.388 0.4117 0.641 0.233 1.76 PRS_PLINK_2.51188643150958e.06 FALSE 480.2 Viral pneumonia Both 93 276 9 respiratory coral4 276, 93 69, 27 69, 16 69, 18 69, 32 0.0928 0.137 0.499 0.3017 1.1 0.838 1.44 -0.365 0.367 0.321 0.4942 0.694 0.338 1.43 -0.401 0.358 0.264 0.5791 0.67 0.332 1.35 0.134 0.324 0.679 0.1681 1.14 0.606 2.16 PRS_PLINK_2.51188643150958e.06 FALSE 480.3 Pneumonia due to fungus (mycoses) Both 81 188 9 respiratory coral4 188, 81 47, 23 47, 16 47, 20 47, 22 -0.0391 0.149 0.793 0.1005 0.962 0.717 1.29 -0.272 0.42 0.518 0.2859 0.762 0.334 1.74 -0.0296 0.392 0.94 0.02697 0.971 0.45 2.09 0.0347 0.38 0.927 0.0328 1.04 0.492 2.18 PRS_PLINK_2.51188643150958e.06 FALSE 480.5 Bronchopneumonia and lung abscess Both 42 180 9 respiratory coral4 180, 42 45, 15 45, 12 45, 5 45, 10 -0.224 0.165 0.176 0.7547 0.799 0.578 1.11 -0.117 0.448 0.795 0.09984 0.89 0.37 2.14 -0.822 0.54 0.128 0.8939 0.44 0.153 1.27 -0.433 0.459 0.346 0.4614 0.649 0.264 1.59 PRS_PLINK_2.51188643150958e.06 TRUE 481 Influenza Both 546 1738 9 respiratory coral4 1738, 546 435, 135 434, 122 434, 161 435, 128 0.00491 0.0509 0.923 0.03474 1 0.909 1.11 -0.08 0.143 0.577 0.2387 0.923 0.697 1.22 0.159 0.137 0.245 0.6109 1.17 0.897 1.53 -0.0523 0.142 0.713 0.1468 0.949 0.718 1.25 PRS_PLINK_2.51188643150958e.06 FALSE 483 Acute bronchitis and bronchiolitis Both 1376 3682 9 respiratory coral4 3682, 1376 921, 340 920, 358 920, 341 921, 337 -0.00414 0.0321 0.898 0.04691 0.996 0.935 1.06 0.0347 0.0898 0.699 0.1556 1.04 0.868 1.23 0.00256 0.0905 0.977 0.009895 1 0.84 1.2 -0.00962 0.0908 0.916 0.03829 0.99 0.829 1.18 PRS_PLINK_2.51188643150958e.06 FALSE 495 Asthma Both 2051 4313 9 respiratory coral4 4313, 2051 1079, 490 1078, 578 1078, 478 1078, 505 0.00479 0.0272 0.861 0.06521 1 0.953 1.06 0.16 0.0761 0.0357 1.447 1.17 1.01 1.36 -0.0234 0.0784 0.766 0.116 0.977 0.838 1.14 0.0386 0.0781 0.622 0.2065 1.04 0.892 1.21 PRS_PLINK_2.51188643150958e.06 FALSE 495.1 Chronic obstructive asthma Both 168 614 9 respiratory coral4 614, 168 154, 54 153, 45 153, 30 154, 39 -0.101 0.0789 0.201 0.6969 0.904 0.775 1.06 -0.169 0.236 0.474 0.3238 0.844 0.531 1.34 -0.555 0.255 0.0297 1.527 0.574 0.348 0.947 -0.315 0.242 0.193 0.7143 0.729 0.454 1.17 PRS_PLINK_2.51188643150958e.06 FALSE 495.11 Chronic obstructive asthma with exacerbation Both 47 146 9 respiratory coral4 146, 47 37, 15 36, 9 36, 11 37, 12 -0.06 0.16 0.707 0.1508 0.942 0.689 1.29 -0.406 0.51 0.426 0.3708 0.666 0.245 1.81 -0.142 0.473 0.765 0.1164 0.868 0.343 2.19 -0.25 0.462 0.589 0.23 0.779 0.315 1.93 PRS_PLINK_2.51188643150958e.06 TRUE 495.2 Asthma with exacerbation Both 589 2154 9 respiratory coral4 2154, 589 539, 141 538, 172 538, 134 539, 142 -0.00511 0.0468 0.913 0.03949 0.995 0.908 1.09 0.215 0.13 0.0969 1.013 1.24 0.962 1.6 -0.0478 0.135 0.724 0.1403 0.953 0.731 1.24 0.00593 0.135 0.965 0.01553 1.01 0.772 1.31 PRS_PLINK_2.51188643150958e.06 FALSE 496 Chronic airway obstruction Both 1366 3870 9 respiratory coral4 3870, 1366 968, 334 967, 393 967, 329 968, 309 -0.0366 0.0313 0.241 0.6171 0.964 0.907 1.02 0.181 0.0884 0.0411 1.386 1.2 1.01 1.42 -0.0183 0.091 0.841 0.07541 0.982 0.821 1.17 -0.0782 0.0923 0.397 0.4017 0.925 0.772 1.11 PRS_PLINK_2.51188643150958e.06 FALSE 496.1 Emphysema Both 561 2743 9 respiratory coral4 2743, 561 686, 130 686, 171 685, 135 686, 125 -0.00348 0.0468 0.941 0.02651 0.997 0.909 1.09 0.313 0.129 0.0154 1.813 1.37 1.06 1.76 0.047 0.134 0.726 0.139 1.05 0.806 1.36 -0.0269 0.136 0.844 0.07371 0.973 0.745 1.27 PRS_PLINK_2.51188643150958e.06 FALSE 496.2 Chronic bronchitis Both 1066 3675 9 respiratory coral4 3675, 1066 919, 251 919, 315 918, 249 919, 250 -0.0314 0.0341 0.358 0.4463 0.969 0.906 1.04 0.245 0.0975 0.0121 1.918 1.28 1.06 1.55 -0.015 0.101 0.883 0.0542 0.985 0.808 1.2 -0.00245 0.102 0.981 0.008422 0.998 0.817 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 496.21 Obstructive chronic bronchitis Both 964 3529 9 respiratory coral4 3529, 964 883, 231 882, 288 882, 222 882, 222 -0.0479 0.0355 0.177 0.7512 0.953 0.889 1.02 0.234 0.101 0.0206 1.685 1.26 1.04 1.54 -0.0508 0.106 0.631 0.2001 0.95 0.772 1.17 -0.0336 0.106 0.751 0.1243 0.967 0.785 1.19 PRS_PLINK_2.51188643150958e.06 FALSE 496.3 Bronchiectasis Both 201 826 9 respiratory coral4 826, 201 207, 61 206, 59 206, 41 207, 39 -0.193 0.0691 0.00523 2.282 0.825 0.72 0.944 -0.00479 0.211 0.982 0.007952 0.995 0.659 1.5 -0.415 0.226 0.0669 1.174 0.66 0.424 1.03 -0.446 0.228 0.0507 1.295 0.64 0.409 1 PRS_PLINK_2.51188643150958e.06 FALSE 497 Bronchitis Both 753 2710 9 respiratory coral4 2710, 753 678, 196 677, 205 677, 161 678, 191 -0.011 0.0407 0.788 0.1036 0.989 0.913 1.07 0.0675 0.115 0.556 0.2548 1.07 0.854 1.34 -0.179 0.12 0.137 0.8647 0.836 0.661 1.06 -0.0107 0.116 0.927 0.03307 0.989 0.788 1.24 PRS_PLINK_2.51188643150958e.06 FALSE 498 Acute bronchospasm Both 194 703 9 respiratory coral4 703, 194 176, 49 176, 49 175, 44 176, 52 -0.00344 0.0847 0.968 0.01429 0.997 0.844 1.18 0.054 0.237 0.82 0.08638 1.06 0.664 1.68 -0.0982 0.236 0.677 0.1694 0.906 0.571 1.44 0.0927 0.233 0.691 0.1606 1.1 0.695 1.73 PRS_PLINK_2.51188643150958e.06 FALSE 499 Cystic fibrosis Both 47 261 9 respiratory coral4 261, 47 66, 19 65, 11 65, 8 65, 9 -0.328 0.157 0.0368 1.434 0.72 0.529 0.98 -0.282 0.425 0.508 0.2944 0.754 0.328 1.74 -0.889 0.47 0.0586 1.232 0.411 0.164 1.03 -0.499 0.446 0.263 0.5793 0.607 0.253 1.46 PRS_PLINK_2.51188643150958e.06 TRUE 500 Lung disease due to external agents Both 161 725 9 respiratory coral4 725, 161 182, 38 181, 43 181, 41 181, 38 -0.0777 0.0882 0.379 0.4219 0.925 0.778 1.1 0.101 0.25 0.686 0.1636 1.11 0.678 1.8 0.0915 0.256 0.721 0.1421 1.1 0.663 1.81 0.0649 0.255 0.799 0.09721 1.07 0.647 1.76 PRS_PLINK_2.51188643150958e.06 FALSE 500.1 Extrinsic allergic alveolitis Both 45 128 9 respiratory coral4 128, 45 32, 13 32, 11 32, 15 32, 6 -0.123 0.192 0.521 0.2835 0.884 0.607 1.29 -0.316 0.503 0.53 0.276 0.729 0.272 1.95 0.128 0.499 0.798 0.09796 1.14 0.427 3.02 -0.485 0.585 0.407 0.3907 0.616 0.196 1.94 PRS_PLINK_2.51188643150958e.06 TRUE 500.2 Pneumoconiosis Both 27 97 9 respiratory coral4 97, 27 25, 9 24, 6 24, 4 24, 7 -0.217 0.182 0.233 0.632 0.805 0.564 1.15 -0.417 0.635 0.511 0.2915 0.659 0.19 2.29 -0.601 0.664 0.365 0.4372 0.548 0.149 2.01 -0.381 0.627 0.544 0.2645 0.684 0.2 2.34 PRS_PLINK_2.51188643150958e.06 TRUE 501 Pneumonitis due to inhalation of food or vomitus Both 271 860 9 respiratory coral4 860, 271 215, 67 215, 62 215, 65 215, 77 0.0534 0.0729 0.464 0.3333 1.05 0.914 1.22 -0.0283 0.203 0.889 0.05103 0.972 0.653 1.45 0.0315 0.202 0.876 0.05752 1.03 0.695 1.53 0.152 0.196 0.438 0.3581 1.16 0.793 1.71 PRS_PLINK_2.51188643150958e.06 FALSE 502 Postinflammatory pulmonary fibrosis Both 308 1113 9 respiratory coral4 1113, 308 279, 91 278, 73 278, 67 278, 76 -0.0306 0.0653 0.639 0.1942 0.97 0.853 1.1 -0.236 0.18 0.19 0.7219 0.79 0.555 1.12 -0.31 0.183 0.0901 1.045 0.733 0.512 1.05 -0.183 0.178 0.306 0.5145 0.833 0.587 1.18 PRS_PLINK_2.51188643150958e.06 FALSE 503 Pulmonary congestion and hypostasis Both 335 1255 9 respiratory coral4 1255, 335 314, 88 314, 82 313, 81 314, 84 0.00664 0.0638 0.917 0.03759 1.01 0.888 1.14 -0.0424 0.176 0.81 0.09152 0.959 0.679 1.35 -0.0496 0.175 0.777 0.1098 0.952 0.676 1.34 -0.0109 0.173 0.95 0.02227 0.989 0.704 1.39 PRS_PLINK_2.51188643150958e.06 FALSE 504 Other alveolar and parietoalveolar pneumonopathy Both 236 835 9 respiratory coral4 835, 236 209, 71 209, 56 208, 56 209, 53 -0.0734 0.0754 0.331 0.4805 0.929 0.802 1.08 -0.289 0.206 0.161 0.7926 0.749 0.5 1.12 -0.257 0.205 0.209 0.6794 0.773 0.517 1.16 -0.327 0.208 0.115 0.9379 0.721 0.48 1.08 PRS_PLINK_2.51188643150958e.06 FALSE 504.1 Idiopathic fibrosing alveolitis Both 124 411 9 respiratory coral4 411, 124 103, 32 103, 32 102, 31 103, 29 0.0164 0.102 0.872 0.0596 1.02 0.833 1.24 -0.0189 0.29 0.948 0.02316 0.981 0.556 1.73 -0.0205 0.293 0.944 0.02494 0.98 0.552 1.74 -0.214 0.301 0.477 0.3215 0.808 0.448 1.46 PRS_PLINK_2.51188643150958e.06 FALSE 505 Other pulmonary inflamation or edema Both 641 2212 9 respiratory coral4 2212, 641 553, 167 553, 140 553, 165 553, 169 -0.00814 0.0461 0.86 0.06561 0.992 0.906 1.09 -0.164 0.13 0.208 0.6809 0.849 0.657 1.1 -0.00867 0.126 0.945 0.02452 0.991 0.774 1.27 0.022 0.125 0.861 0.06522 1.02 0.799 1.31 PRS_PLINK_2.51188643150958e.06 FALSE 506 Empyema and pneumothorax Both 740 3311 9 respiratory coral4 3311, 740 828, 212 828, 170 827, 172 828, 186 -0.0203 0.0413 0.623 0.2057 0.98 0.904 1.06 -0.206 0.115 0.0729 1.138 0.814 0.65 1.02 -0.213 0.114 0.0622 1.206 0.808 0.646 1.01 -0.141 0.113 0.21 0.6776 0.868 0.696 1.08 PRS_PLINK_2.51188643150958e.06 FALSE 507 Pleurisy; pleural effusion Both 1024 3545 9 respiratory coral4 3545, 1024 887, 280 886, 193 886, 292 886, 258 0.0214 0.0358 0.55 0.2596 1.02 0.952 1.1 -0.349 0.105 0.000931 3.031 0.705 0.574 0.867 0.0472 0.0968 0.626 0.2033 1.05 0.867 1.27 -0.0698 0.0991 0.481 0.3177 0.933 0.768 1.13 PRS_PLINK_2.51188643150958e.06 FALSE 508 Pulmonary collapse; interstitial and compensatory emphysema Both 836 3105 9 respiratory coral4 3105, 836 777, 249 776, 177 776, 206 776, 203 -0.0243 0.0391 0.536 0.2712 0.976 0.904 1.05 -0.32 0.111 0.00388 2.412 0.726 0.584 0.902 -0.18 0.107 0.0948 1.023 0.836 0.677 1.03 -0.192 0.108 0.0767 1.115 0.826 0.668 1.02 PRS_PLINK_2.51188643150958e.06 FALSE 509 Respiratory failure, insufficiency, arrest Both 1279 3939 9 respiratory coral4 3939, 1279 985, 343 985, 269 984, 329 985, 337 0.00838 0.0333 0.801 0.09612 1.01 0.945 1.08 -0.223 0.0942 0.0178 1.751 0.8 0.665 0.962 -0.0254 0.0906 0.779 0.1085 0.975 0.816 1.16 -0.00819 0.0905 0.928 0.0325 0.992 0.831 1.18 PRS_PLINK_2.51188643150958e.06 FALSE 509.1 Respiratory failure Both 746 2574 9 respiratory coral4 2574, 746 644, 204 643, 146 643, 198 644, 197 0.0058 0.0432 0.893 0.04903 1.01 0.924 1.09 -0.313 0.122 0.0105 1.977 0.731 0.576 0.93 -0.0195 0.115 0.865 0.06304 0.981 0.783 1.23 -0.0209 0.115 0.856 0.06749 0.979 0.782 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 509.2 Respiratory insufficiency Both 454 1597 9 respiratory coral4 1597, 454 400, 123 399, 100 399, 100 399, 130 0.0342 0.054 0.527 0.2785 1.03 0.931 1.15 -0.179 0.153 0.242 0.6156 0.836 0.619 1.13 -0.184 0.154 0.231 0.6361 0.832 0.615 1.12 0.0588 0.146 0.687 0.1632 1.06 0.797 1.41 PRS_PLINK_2.51188643150958e.06 FALSE 509.3 Pulmonary insufficiency or respiratory failure following trauma and surgery Both 483 2188 9 respiratory coral4 2188, 483 547, 128 547, 101 547, 127 547, 127 0.0384 0.0535 0.473 0.3252 1.04 0.936 1.15 -0.236 0.147 0.107 0.9714 0.79 0.592 1.05 0.00555 0.139 0.968 0.01401 1.01 0.765 1.32 -0.0249 0.14 0.859 0.06615 0.975 0.741 1.28 PRS_PLINK_2.51188643150958e.06 FALSE 509.8 Dependence on respirator [Ventilator] or supplemental oxygen Both 575 2353 9 respiratory coral4 2353, 575 589, 155 588, 134 588, 136 588, 149 -0.0253 0.0473 0.593 0.2268 0.975 0.889 1.07 -0.131 0.132 0.321 0.4934 0.877 0.678 1.14 -0.129 0.131 0.324 0.4901 0.879 0.679 1.14 -0.057 0.129 0.659 0.1809 0.945 0.733 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 510 Other diseases of lung Both 1962 4990 9 respiratory coral4 4990, 1962 1248, 508 1247, 486 1247, 467 1248, 500 0.000366 0.0271 0.989 0.0047 1 0.949 1.05 -0.0409 0.0764 0.593 0.2272 0.96 0.827 1.11 -0.0661 0.0771 0.391 0.4077 0.936 0.805 1.09 -0.000282 0.0762 0.997 0.001284 1 0.861 1.16 PRS_PLINK_2.51188643150958e.06 FALSE 510.2 Lung transplant Both 67 202 9 respiratory coral4 202, 67 51, 19 50, 14 50, 17 51, 17 0.113 0.146 0.437 0.3593 1.12 0.841 1.49 -0.162 0.426 0.703 0.1529 0.85 0.369 1.96 0.0657 0.405 0.871 0.0599 1.07 0.483 2.36 0.0997 0.406 0.806 0.09375 1.1 0.499 2.45 PRS_PLINK_2.51188643150958e.06 FALSE 512 Other symptoms of respiratory system Both 5390 2061 9 respiratory coral4 2061, 5390 516, 1283 515, 1355 515, 1358 515, 1393 0.0438 0.026 0.0918 1.037 1.04 0.993 1.1 0.0559 0.0752 0.457 0.3399 1.06 0.913 1.23 0.0673 0.0751 0.371 0.4312 1.07 0.923 1.24 0.101 0.0747 0.177 0.752 1.11 0.955 1.28 PRS_PLINK_2.51188643150958e.06 FALSE 512.1 Wheezing Both 608 1070 9 respiratory coral4 1070, 608 268, 150 267, 147 267, 165 268, 146 0.0376 0.0501 0.453 0.3437 1.04 0.941 1.15 -0.0121 0.147 0.934 0.02953 0.988 0.741 1.32 0.12 0.145 0.408 0.3892 1.13 0.849 1.5 -0.0194 0.147 0.895 0.04817 0.981 0.736 1.31 PRS_PLINK_2.51188643150958e.06 FALSE 512.2 Painful respiration Both 937 1640 9 respiratory coral4 1640, 937 410, 238 410, 232 410, 250 410, 217 -0.00424 0.0412 0.918 0.03708 0.996 0.918 1.08 0.00653 0.118 0.956 0.0196 1.01 0.799 1.27 0.0796 0.117 0.497 0.3039 1.08 0.861 1.36 -0.0949 0.119 0.424 0.3727 0.909 0.721 1.15 PRS_PLINK_2.51188643150958e.06 FALSE 512.3 Abnormal chest sounds Both 154 223 9 respiratory coral4 223, 154 56, 43 56, 22 55, 43 56, 46 0.102 0.105 0.328 0.4839 1.11 0.902 1.36 -0.579 0.327 0.0771 1.113 0.561 0.295 1.07 0.03 0.297 0.919 0.03651 1.03 0.576 1.84 0.146 0.293 0.62 0.2077 1.16 0.651 2.06 PRS_PLINK_2.51188643150958e.06 FALSE 512.7 Shortness of breath Both 3559 2057 9 respiratory coral4 2057, 3559 515, 860 514, 885 514, 901 514, 912 0.0453 0.0282 0.108 0.9652 1.05 0.99 1.11 0.0217 0.0817 0.79 0.1022 1.02 0.871 1.2 0.0622 0.0814 0.445 0.3521 1.06 0.907 1.25 0.0667 0.081 0.41 0.3867 1.07 0.912 1.25 PRS_PLINK_2.51188643150958e.06 FALSE 512.8 Cough Both 3477 2060 9 respiratory coral4 2060, 3477 515, 822 515, 898 515, 893 515, 864 0.0365 0.0287 0.203 0.6924 1.04 0.98 1.1 0.0889 0.0816 0.276 0.5585 1.09 0.931 1.28 0.0957 0.0816 0.241 0.6179 1.1 0.938 1.29 0.0607 0.0813 0.455 0.3418 1.06 0.906 1.25 PRS_PLINK_2.51188643150958e.06 FALSE 512.9 Other dyspnea Both 3612 2058 9 respiratory coral4 2058, 3612 515, 884 514, 885 514, 883 515, 959 0.0388 0.0276 0.161 0.7935 1.04 0.985 1.1 -0.00561 0.0812 0.945 0.02462 0.994 0.848 1.17 0.0178 0.081 0.826 0.08302 1.02 0.869 1.19 0.0918 0.08 0.251 0.6001 1.1 0.937 1.28 PRS_PLINK_2.51188643150958e.06 FALSE 513 Respiratory abnormalities Both 4009 3441 9 respiratory coral4 3441, 4009 861, 988 860, 951 860, 1011 860, 1058 0.0287 0.0237 0.225 0.6483 1.03 0.982 1.08 -0.0396 0.0677 0.559 0.2527 0.961 0.842 1.1 0.0243 0.0674 0.719 0.1435 1.02 0.898 1.17 0.08 0.0671 0.233 0.6328 1.08 0.95 1.24 PRS_PLINK_2.51188643150958e.06 FALSE 513.3 Hypoventilation Both 384 1025 9 respiratory coral4 1025, 384 257, 93 256, 84 256, 114 256, 93 0.0204 0.0623 0.743 0.1292 1.02 0.903 1.15 -0.109 0.178 0.54 0.2673 0.897 0.632 1.27 0.221 0.167 0.186 0.7312 1.25 0.899 1.73 -0.00158 0.174 0.993 0.00316 0.998 0.71 1.4 PRS_PLINK_2.51188643150958e.06 FALSE 513.31 Apnea Both 183 506 9 respiratory coral4 506, 183 127, 45 126, 40 126, 50 127, 48 0.0519 0.0954 0.587 0.2316 1.05 0.874 1.27 -0.208 0.26 0.423 0.3738 0.812 0.488 1.35 0.153 0.246 0.533 0.273 1.17 0.72 1.89 0.0414 0.253 0.87 0.06055 1.04 0.635 1.71 PRS_PLINK_2.51188643150958e.06 FALSE 513.32 Orthopnea Both 96 233 9 respiratory coral4 233, 96 59, 22 58, 21 58, 32 58, 21 0.103 0.138 0.456 0.3414 1.11 0.846 1.45 0.17 0.384 0.658 0.1815 1.19 0.558 2.52 0.632 0.361 0.0798 1.098 1.88 0.928 3.81 0.177 0.38 0.642 0.1923 1.19 0.566 2.51 PRS_PLINK_2.51188643150958e.06 FALSE 513.4 Hyperventilation Both 196 524 9 respiratory coral4 524, 196 131, 55 131, 48 131, 57 131, 36 -0.0897 0.0864 0.299 0.5241 0.914 0.772 1.08 -0.0588 0.24 0.807 0.09321 0.943 0.589 1.51 0.0502 0.228 0.826 0.08291 1.05 0.672 1.65 -0.426 0.253 0.0926 1.033 0.653 0.398 1.07 PRS_PLINK_2.51188643150958e.06 FALSE 513.8 Disorders of diaphragm Both 88 265 9 respiratory coral4 265, 88 67, 20 66, 14 66, 24 66, 29 -0.0124 0.106 0.907 0.0423 0.988 0.802 1.22 -0.329 0.39 0.399 0.3987 0.72 0.335 1.55 0.16 0.353 0.65 0.1868 1.17 0.588 2.34 0.418 0.351 0.234 0.6313 1.52 0.763 3.02 PRS_PLINK_2.51188643150958e.06 FALSE 514 Abnormal findings examination of lungs Both 1578 5137 9 respiratory coral4 5137, 1578 1285, 414 1284, 364 1284, 412 1284, 387 -0.018 0.0291 0.537 0.2702 0.982 0.928 1.04 -0.129 0.0828 0.12 0.9222 0.879 0.747 1.03 0.00627 0.0811 0.938 0.02762 1.01 0.858 1.18 -0.0535 0.0821 0.515 0.2884 0.948 0.807 1.11 PRS_PLINK_2.51188643150958e.06 FALSE 514.1 Abnormal results of function study of pulmonary system Both 102 432 9 respiratory coral4 432, 102 108, 32 108, 17 108, 24 108, 29 -0.146 0.109 0.178 0.7492 0.864 0.698 1.07 -0.573 0.328 0.081 1.091 0.564 0.296 1.07 -0.207 0.32 0.519 0.2849 0.813 0.434 1.52 -0.0306 0.298 0.918 0.03703 0.97 0.541 1.74 PRS_PLINK_2.51188643150958e.06 FALSE 514.2 Solitary pulmonary nodule Both 815 4136 9 respiratory coral4 4136, 815 1034, 192 1034, 187 1034, 245 1034, 191 0.0352 0.0401 0.38 0.4206 1.04 0.958 1.12 -0.0291 0.112 0.795 0.09949 0.971 0.78 1.21 0.262 0.106 0.0139 1.856 1.3 1.05 1.6 0.0114 0.112 0.919 0.03689 1.01 0.812 1.26 PRS_PLINK_2.51188643150958e.06 FALSE 516 Abnormal sputum Both 296 1212 9 respiratory coral4 1212, 296 303, 87 303, 82 303, 69 303, 58 -0.12 0.0644 0.0634 1.198 0.887 0.782 1.01 -0.0281 0.176 0.874 0.05871 0.972 0.688 1.37 -0.228 0.182 0.209 0.6799 0.796 0.557 1.14 -0.342 0.189 0.0711 1.148 0.711 0.49 1.03 PRS_PLINK_2.51188643150958e.06 FALSE 516.1 Hemoptysis Both 250 1018 9 respiratory coral4 1018, 250 255, 81 254, 67 254, 57 255, 45 -0.185 0.0686 0.00689 2.162 0.831 0.726 0.95 -0.176 0.19 0.355 0.4495 0.839 0.578 1.22 -0.353 0.195 0.07 1.155 0.702 0.479 1.03 -0.553 0.208 0.00768 2.115 0.575 0.383 0.864 PRS_PLINK_2.51188643150958e.06 FALSE 519 Other diseases of respiratory system, not elsewhere classified Both 2016 5314 9 respiratory coral4 5314, 2016 1329, 521 1328, 460 1328, 532 1329, 502 0.0012 0.0265 0.964 0.01591 1 0.95 1.05 -0.131 0.076 0.0844 1.074 0.877 0.756 1.02 0.0262 0.0738 0.723 0.1409 1.03 0.888 1.19 -0.0371 0.075 0.621 0.207 0.964 0.832 1.12 PRS_PLINK_2.51188643150958e.06 FALSE 519.1 Tracheostomy complications Both 53 284 9 respiratory coral4 284, 53 71, 15 71, 12 71, 10 71, 16 0.00102 0.161 0.995 0.002209 1 0.731 1.37 -0.233 0.428 0.587 0.2315 0.792 0.342 1.83 -0.275 0.446 0.537 0.2702 0.759 0.317 1.82 0.0975 0.396 0.805 0.09407 1.1 0.508 2.39 PRS_PLINK_2.51188643150958e.06 FALSE 519.2 Respiratory complications Both 126 557 9 respiratory coral4 557, 126 140, 31 139, 33 139, 34 139, 28 0.017 0.0982 0.863 0.06409 1.02 0.839 1.23 0.0839 0.279 0.763 0.1172 1.09 0.63 1.88 0.161 0.277 0.561 0.251 1.17 0.683 2.02 -0.102 0.286 0.721 0.1423 0.903 0.515 1.58 PRS_PLINK_2.51188643150958e.06 FALSE 519.8 Other diseases of respiratory system, NEC Both 512 2234 9 respiratory coral4 2234, 512 559, 130 558, 123 558, 131 559, 128 0.0296 0.0508 0.561 0.2514 1.03 0.932 1.14 -0.0538 0.139 0.699 0.1558 0.948 0.722 1.24 0.0142 0.138 0.918 0.03707 1.01 0.774 1.33 -0.00245 0.139 0.986 0.006146 0.998 0.76 1.31 PRS_PLINK_2.51188643150958e.06 FALSE 519.9 Symptoms involving respiratory system and other chest symptoms Both 1539 4819 9 respiratory coral4 4819, 1539 1205, 404 1205, 355 1204, 397 1205, 382 -0.0125 0.0294 0.67 0.1738 0.988 0.932 1.05 -0.123 0.0844 0.144 0.8416 0.884 0.749 1.04 -0.014 0.0824 0.865 0.06313 0.986 0.839 1.16 -0.0521 0.0834 0.532 0.2738 0.949 0.806 1.12 PRS_PLINK_2.51188643150958e.06 FALSE 520 Disorders of tooth development Both 53 490 10 digestive chartreuse4 490, 53 123, 12 122, 14 122, 11 123, 16 0.127 0.164 0.439 0.3575 1.14 0.823 1.56 0.0562 0.407 0.89 0.05052 1.06 0.476 2.35 -0.19 0.427 0.657 0.1824 0.827 0.358 1.91 0.401 0.399 0.315 0.5014 1.49 0.683 3.26 PRS_PLINK_2.51188643150958e.06 FALSE 520.1 Hereditary disturbances in tooth structure Both 35 266 10 digestive chartreuse4 266, 35 67, 12 66, 8 66, 4 67, 11 -0.142 0.225 0.528 0.2777 0.868 0.558 1.35 -0.405 0.491 0.409 0.3881 0.667 0.255 1.75 -1.02 0.565 0.0724 1.14 0.362 0.12 1.1 -0.0606 0.47 0.898 0.04695 0.941 0.374 2.37 PRS_PLINK_2.51188643150958e.06 TRUE 520.2 Disturbances in tooth eruption Both 18 254 10 digestive chartreuse4 254, 18 64, 0 63, 5 63, 7 64, 6 0.498 0.28 0.0753 1.123 1.64 0.951 2.85 2 1.1 0.0688 1.162 7.37 0.857 63.4 2.64 1.16 0.0228 1.642 14 1.44 135 1.84 1.02 0.0727 1.139 6.28 0.844 46.8 PRS_PLINK_2.51188643150958e.06 TRUE 521 Diseases of hard tissues of teeth Both 221 1289 10 digestive chartreuse4 1289, 221 323, 53 322, 58 322, 59 322, 50 -0.0596 0.0707 0.399 0.3988 0.942 0.82 1.08 0.0717 0.205 0.727 0.1387 1.07 0.719 1.61 0.127 0.204 0.533 0.2731 1.14 0.761 1.7 -0.0932 0.212 0.66 0.1803 0.911 0.601 1.38 PRS_PLINK_2.51188643150958e.06 FALSE 521.1 Dental caries Both 207 1200 10 digestive chartreuse4 1200, 207 300, 47 300, 59 300, 51 300, 49 -0.0594 0.0728 0.415 0.382 0.942 0.817 1.09 0.197 0.212 0.353 0.4519 1.22 0.804 1.84 0.0706 0.218 0.746 0.1274 1.07 0.7 1.64 0.0182 0.218 0.934 0.02985 1.02 0.664 1.56 PRS_PLINK_2.51188643150958e.06 FALSE 521.2 Dental abrasion, erosion and attrition Both 13 78 10 digestive chartreuse4 78, 13 20, 3 19, 1 19, 7 20, 2 -0.0993 0.292 0.734 0.1344 0.905 0.511 1.6 -0.298 1.07 0.78 0.1077 0.742 0.0915 6.02 1.41 0.929 0.129 0.8908 4.1 0.664 25.3 -0.306 1.02 0.765 0.1164 0.737 0.0994 5.46 PRS_PLINK_2.51188643150958e.06 TRUE 522 Diseases of pulp and periapical tissues Both 172 750 10 digestive chartreuse4 750, 172 188, 37 187, 50 187, 49 188, 36 0.0246 0.0899 0.784 0.1055 1.02 0.859 1.22 0.306 0.241 0.203 0.6932 1.36 0.848 2.18 0.249 0.241 0.302 0.5206 1.28 0.8 2.05 -0.0113 0.253 0.964 0.01577 0.989 0.603 1.62 PRS_PLINK_2.51188643150958e.06 FALSE 522.5 Periapical abscess Both 158 651 10 digestive chartreuse4 651, 158 163, 33 163, 46 162, 46 163, 33 -0.0168 0.0994 0.866 0.06253 0.983 0.809 1.19 0.296 0.253 0.242 0.6171 1.35 0.819 2.21 0.324 0.255 0.204 0.6903 1.38 0.839 2.28 -0.000911 0.266 0.997 0.001188 0.999 0.593 1.68 PRS_PLINK_2.51188643150958e.06 FALSE 523 Gingival and periodontal diseases Both 222 1038 10 digestive chartreuse4 1038, 222 260, 46 259, 49 259, 64 260, 63 0.102 0.0814 0.209 0.6799 1.11 0.944 1.3 0.0793 0.223 0.722 0.1417 1.08 0.7 1.67 0.317 0.212 0.134 0.872 1.37 0.907 2.08 0.347 0.214 0.104 0.9833 1.42 0.931 2.15 PRS_PLINK_2.51188643150958e.06 FALSE 523.1 Gingivitis Both 51 199 10 digestive chartreuse4 199, 51 50, 10 50, 6 49, 22 50, 13 0.027 0.164 0.869 0.06102 1.03 0.745 1.42 -0.542 0.534 0.311 0.5075 0.582 0.204 1.66 0.799 0.439 0.069 1.161 2.22 0.94 5.26 0.245 0.458 0.593 0.227 1.28 0.52 3.14 PRS_PLINK_2.51188643150958e.06 FALSE 523.3 Periodontitis (acute or chronic) Both 110 528 10 digestive chartreuse4 528, 110 132, 25 132, 24 132, 29 132, 32 0.0938 0.119 0.431 0.3656 1.1 0.87 1.39 -0.0304 0.311 0.922 0.03527 0.97 0.528 1.78 0.147 0.299 0.623 0.2057 1.16 0.644 2.08 0.221 0.296 0.455 0.3422 1.25 0.698 2.23 PRS_PLINK_2.51188643150958e.06 FALSE 523.31 Acute periodontitis Both 97 462 10 digestive chartreuse4 462, 97 116, 25 115, 18 115, 25 116, 29 0.0973 0.135 0.471 0.3271 1.1 0.846 1.44 -0.313 0.336 0.352 0.4529 0.732 0.379 1.41 0.0183 0.314 0.954 0.02062 1.02 0.55 1.88 0.116 0.304 0.702 0.1536 1.12 0.619 2.04 PRS_PLINK_2.51188643150958e.06 FALSE 523.32 Chronic periodontitis Both 23 175 10 digestive chartreuse4 175, 23 44, 5 44, 7 43, 4 44, 7 0.0568 0.271 0.834 0.07885 1.06 0.622 1.8 0.228 0.587 0.697 0.1565 1.26 0.397 3.97 -0.379 0.681 0.577 0.2385 0.684 0.18 2.6 0.563 0.632 0.373 0.4283 1.76 0.509 6.06 PRS_PLINK_2.51188643150958e.06 TRUE 524 Dentofacial anomalies, including malocclusion Both 42 413 10 digestive chartreuse4 413, 42 104, 11 103, 10 103, 8 103, 13 -0.0883 0.136 0.515 0.2882 0.915 0.702 1.19 -0.149 0.436 0.733 0.1348 0.862 0.367 2.03 -0.332 0.467 0.476 0.3222 0.717 0.287 1.79 0.148 0.426 0.728 0.138 1.16 0.503 2.67 PRS_PLINK_2.51188643150958e.06 TRUE 524.3 Anomalies of tooth position/malocclusion Both 24 217 10 digestive chartreuse4 217, 24 55, 8 54, 5 54, 4 54, 7 -0.248 0.163 0.128 0.8916 0.781 0.567 1.07 -0.397 0.564 0.481 0.3176 0.672 0.223 2.03 -0.757 0.608 0.214 0.6703 0.469 0.142 1.55 -0.28 0.567 0.621 0.2067 0.756 0.249 2.3 PRS_PLINK_2.51188643150958e.06 TRUE 525 Other diseases of the teeth and supporting structures Both 307 1524 10 digestive chartreuse4 1524, 307 381, 80 381, 72 381, 70 381, 84 -0.0149 0.0622 0.811 0.09121 0.985 0.872 1.11 -0.105 0.178 0.554 0.2567 0.9 0.635 1.28 -0.107 0.179 0.548 0.261 0.898 0.632 1.28 0.0428 0.173 0.805 0.0943 1.04 0.743 1.47 PRS_PLINK_2.51188643150958e.06 FALSE 525.1 Loss of teeth or edentulism Both 90 538 10 digestive chartreuse4 538, 90 135, 31 134, 15 134, 18 135, 25 -0.205 0.1 0.0406 1.392 0.815 0.67 0.991 -0.633 0.333 0.0571 1.244 0.531 0.276 1.02 -0.56 0.324 0.0838 1.077 0.571 0.303 1.08 -0.313 0.304 0.304 0.5178 0.731 0.403 1.33 PRS_PLINK_2.51188643150958e.06 FALSE 526 Diseases of the jaws Both 691 3912 10 digestive chartreuse4 3912, 691 978, 158 978, 175 978, 176 978, 182 0.0246 0.0418 0.557 0.2541 1.02 0.944 1.11 0.102 0.119 0.389 0.41 1.11 0.878 1.4 0.0956 0.119 0.422 0.3751 1.1 0.871 1.39 0.158 0.118 0.182 0.7397 1.17 0.929 1.48 PRS_PLINK_2.51188643150958e.06 FALSE 526.1 Cysts of the jaws Both 19 313 10 digestive chartreuse4 313, 19 79, 4 78, 4 78, 6 78, 5 0.108 0.234 0.644 0.1914 1.11 0.704 1.76 -0.088 0.623 0.888 0.05178 0.916 0.27 3.1 0.385 0.596 0.519 0.2851 1.47 0.457 4.73 0.263 0.601 0.661 0.1797 1.3 0.401 4.23 PRS_PLINK_2.51188643150958e.06 TRUE 526.3 Anomalies of jaw size/symmetry Both 32 263 10 digestive chartreuse4 263, 32 66, 5 66, 1 65, 12 66, 14 0.415 0.224 0.0636 1.197 1.51 0.977 2.35 -1.26 0.834 0.131 0.8815 0.284 0.0554 1.46 0.619 0.526 0.239 0.6212 1.86 0.663 5.2 1.05 0.546 0.0547 1.262 2.86 0.979 8.32 PRS_PLINK_2.51188643150958e.06 TRUE 526.4 Temporomandibular joint disorders Both 433 2277 10 digestive chartreuse4 2277, 433 570, 88 569, 119 569, 106 569, 120 0.0575 0.0544 0.291 0.5362 1.06 0.952 1.18 0.311 0.153 0.0417 1.38 1.36 1.01 1.84 0.155 0.156 0.32 0.495 1.17 0.86 1.59 0.331 0.153 0.0311 1.507 1.39 1.03 1.88 PRS_PLINK_2.51188643150958e.06 FALSE 526.41 Temporomandibular joint disorder, unspecified Both 334 1794 10 digestive chartreuse4 1794, 334 449, 71 448, 95 448, 82 449, 86 0.0144 0.0601 0.811 0.09108 1.01 0.902 1.14 0.301 0.17 0.0771 1.113 1.35 0.968 1.89 0.116 0.177 0.513 0.2896 1.12 0.793 1.59 0.221 0.175 0.207 0.6845 1.25 0.885 1.76 PRS_PLINK_2.51188643150958e.06 FALSE 526.42 Arthralgia/ankylosis of temporomandibular joint Both 184 1089 10 digestive chartreuse4 1089, 184 273, 41 272, 39 272, 45 272, 59 0.104 0.0861 0.226 0.6453 1.11 0.937 1.31 -0.0338 0.237 0.887 0.05221 0.967 0.607 1.54 0.0603 0.233 0.796 0.09913 1.06 0.673 1.68 0.353 0.224 0.115 0.9392 1.42 0.918 2.21 PRS_PLINK_2.51188643150958e.06 FALSE 526.5 Inflammatory conditions of jaw Both 49 449 10 digestive chartreuse4 449, 49 113, 13 112, 11 112, 15 112, 10 -0.176 0.119 0.137 0.864 0.838 0.664 1.06 0.0241 0.423 0.955 0.02018 1.02 0.447 2.35 0.215 0.397 0.589 0.2301 1.24 0.569 2.7 -0.165 0.426 0.699 0.1553 0.848 0.368 1.96 PRS_PLINK_2.51188643150958e.06 TRUE 526.8 Exostosis of jaw Both 14 78 10 digestive chartreuse4 78, 14 20, 5 19, 1 19, 2 20, 6 0.36 0.327 0.271 0.5677 1.43 0.756 2.72 -0.926 0.998 0.353 0.4517 0.396 0.0561 2.8 -0.732 0.931 0.432 0.365 0.481 0.0775 2.98 0.169 0.717 0.814 0.08953 1.18 0.29 4.83 PRS_PLINK_2.51188643150958e.06 TRUE 526.9 Jaw disease NOS Both 94 722 10 digestive chartreuse4 722, 94 181, 32 180, 19 180, 22 181, 21 -0.148 0.103 0.153 0.816 0.863 0.704 1.06 -0.474 0.305 0.12 0.9206 0.623 0.343 1.13 -0.353 0.297 0.235 0.6298 0.702 0.392 1.26 -0.336 0.301 0.264 0.5785 0.714 0.396 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 527 Diseases of the salivary glands Both 502 2775 10 digestive chartreuse4 2775, 502 693, 108 694, 113 693, 150 694, 131 0.0994 0.0501 0.0474 1.324 1.1 1 1.22 0.0321 0.145 0.825 0.0836 1.03 0.777 1.37 0.337 0.137 0.0143 1.843 1.4 1.07 1.83 0.219 0.141 0.12 0.9204 1.25 0.944 1.64 PRS_PLINK_2.51188643150958e.06 FALSE 527.1 Hypertrophy of salivary gland Both 19 101 10 digestive chartreuse4 101, 19 26, 9 25, 3 25, 1 25, 6 -0.201 0.196 0.303 0.5178 0.818 0.557 1.2 -0.899 0.733 0.22 0.6575 0.407 0.0967 1.71 -1.58 1.02 0.124 0.9073 0.207 0.0277 1.54 -0.21 0.602 0.728 0.1381 0.811 0.249 2.64 PRS_PLINK_2.51188643150958e.06 TRUE 527.2 Sialoadenitis Both 119 597 10 digestive chartreuse4 597, 119 150, 29 149, 27 149, 26 149, 37 0.0576 0.101 0.568 0.2457 1.06 0.869 1.29 -0.0798 0.294 0.786 0.1043 0.923 0.519 1.64 -0.0738 0.295 0.802 0.09565 0.929 0.521 1.65 0.249 0.277 0.369 0.4335 1.28 0.745 2.21 PRS_PLINK_2.51188643150958e.06 FALSE 527.7 Disturbance of salivary secretion Both 285 1533 10 digestive chartreuse4 1533, 285 384, 59 383, 55 383, 90 383, 81 0.199 0.0744 0.00748 2.126 1.22 1.05 1.41 -0.0583 0.2 0.77 0.1134 0.943 0.638 1.4 0.438 0.184 0.017 1.77 1.55 1.08 2.22 0.377 0.187 0.0435 1.361 1.46 1.01 2.1 PRS_PLINK_2.51188643150958e.06 FALSE 527.8 Other specified diseases of the salivary glands Both 67 399 10 digestive chartreuse4 399, 67 99, 13 100, 22 99, 12 100, 20 0.195 0.142 0.171 0.7659 1.21 0.919 1.61 0.578 0.382 0.131 0.8826 1.78 0.842 3.77 -0.0877 0.414 0.832 0.07973 0.916 0.407 2.06 0.485 0.389 0.212 0.6738 1.62 0.758 3.48 PRS_PLINK_2.51188643150958e.06 FALSE 528 Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue Both 773 4006 10 digestive chartreuse4 4006, 773 1002, 188 1001, 197 1001, 188 1002, 200 0.0241 0.0393 0.54 0.2674 1.02 0.948 1.11 0.0393 0.112 0.725 0.1398 1.04 0.836 1.29 0.00655 0.113 0.954 0.02062 1.01 0.807 1.26 0.0822 0.111 0.459 0.3378 1.09 0.873 1.35 PRS_PLINK_2.51188643150958e.06 FALSE 528.1 Stomatitis and mucositis Both 234 1015 10 digestive chartreuse4 1015, 234 254, 61 254, 50 253, 70 254, 53 0.00968 0.0741 0.896 0.04771 1.01 0.873 1.17 -0.215 0.211 0.308 0.5115 0.807 0.534 1.22 0.116 0.197 0.555 0.2561 1.12 0.764 1.65 -0.0916 0.209 0.66 0.1802 0.912 0.606 1.37 PRS_PLINK_2.51188643150958e.06 FALSE 528.11 Stomatitis and mucositis (ulcerative) Both 67 326 10 digestive chartreuse4 326, 67 82, 14 81, 11 81, 27 82, 15 0.136 0.14 0.33 0.4817 1.15 0.871 1.51 -0.0981 0.423 0.817 0.0879 0.907 0.395 2.08 0.71 0.366 0.052 1.284 2.03 0.994 4.17 0.268 0.409 0.513 0.29 1.31 0.586 2.92 PRS_PLINK_2.51188643150958e.06 FALSE 528.12 Oral aphthae Both 91 347 10 digestive chartreuse4 347, 91 87, 25 87, 20 86, 20 87, 26 -0.00591 0.12 0.961 0.01744 0.994 0.786 1.26 -0.137 0.339 0.687 0.1631 0.872 0.449 1.7 -0.204 0.339 0.547 0.2619 0.815 0.419 1.58 0.109 0.326 0.737 0.1325 1.12 0.589 2.11 PRS_PLINK_2.51188643150958e.06 FALSE 528.3 Cellulitis and abscess of oral soft tissues Both 42 330 10 digestive chartreuse4 330, 42 83, 13 82, 12 82, 10 83, 7 -0.212 0.162 0.19 0.7209 0.809 0.589 1.11 -0.0295 0.426 0.945 0.0247 0.971 0.421 2.24 -0.299 0.453 0.51 0.2925 0.742 0.305 1.8 -0.611 0.475 0.198 0.7025 0.543 0.214 1.38 PRS_PLINK_2.51188643150958e.06 TRUE 528.4 Cysts of oral soft tissues Both 26 181 10 digestive chartreuse4 181, 26 46, 3 45, 7 45, 7 45, 9 0.194 0.276 0.482 0.3172 1.21 0.707 2.09 0.606 0.711 0.394 0.4041 1.83 0.455 7.38 0.449 0.701 0.521 0.2828 1.57 0.397 6.19 1.02 0.652 0.119 0.9236 2.76 0.769 9.91 PRS_PLINK_2.51188643150958e.06 TRUE 528.41 Cyst of the salivary gland Both 17 108 10 digestive chartreuse4 108, 17 27, 2 27, 6 27, 5 27, 4 -0.0086 0.308 0.978 0.009789 0.991 0.542 1.81 0.863 0.94 0.359 0.4455 2.37 0.376 15 0.913 0.958 0.341 0.4676 2.49 0.381 16.3 0.232 0.875 0.791 0.102 1.26 0.227 7.01 PRS_PLINK_2.51188643150958e.06 TRUE 528.5 Diseases of lips Both 172 772 10 digestive chartreuse4 772, 172 193, 44 193, 44 193, 32 193, 52 0.0338 0.0843 0.688 0.1624 1.03 0.877 1.22 0.016 0.238 0.946 0.02396 1.02 0.638 1.62 -0.338 0.259 0.191 0.7193 0.713 0.43 1.18 0.203 0.231 0.379 0.4217 1.23 0.779 1.93 PRS_PLINK_2.51188643150958e.06 FALSE 528.6 Leukoplakia of oral mucosa Both 27 208 10 digestive chartreuse4 208, 27 52, 7 52, 7 52, 4 52, 9 -0.00739 0.207 0.971 0.01256 0.993 0.662 1.49 0.0543 0.585 0.926 0.03335 1.06 0.335 3.33 -0.527 0.635 0.407 0.3906 0.59 0.17 2.05 0.255 0.538 0.635 0.1972 1.29 0.45 3.7 PRS_PLINK_2.51188643150958e.06 TRUE 528.7 Sialolithiasis Both 35 213 10 digestive chartreuse4 213, 35 54, 9 53, 9 53, 10 53, 7 -0.176 0.181 0.331 0.4802 0.839 0.588 1.2 -0.0266 0.562 0.962 0.01671 0.974 0.323 2.93 0.112 0.493 0.821 0.08572 1.12 0.426 2.94 -0.317 0.548 0.563 0.2498 0.728 0.249 2.13 PRS_PLINK_2.51188643150958e.06 TRUE 529 Diseases and other conditions of the tongue Both 228 1038 10 digestive chartreuse4 1038, 228 260, 47 259, 61 259, 68 260, 52 0.0907 0.0749 0.226 0.6465 1.09 0.946 1.27 0.256 0.213 0.231 0.6371 1.29 0.85 1.96 0.438 0.212 0.0385 1.415 1.55 1.02 2.35 0.0762 0.221 0.73 0.1367 1.08 0.7 1.66 PRS_PLINK_2.51188643150958e.06 FALSE 529.1 Glossitis Both 60 220 10 digestive chartreuse4 220, 60 55, 13 55, 18 55, 19 55, 10 0.0705 0.142 0.618 0.2087 1.07 0.813 1.42 0.337 0.428 0.431 0.3652 1.4 0.605 3.24 0.589 0.424 0.165 0.7832 1.8 0.785 4.14 -0.206 0.475 0.664 0.1779 0.814 0.321 2.06 PRS_PLINK_2.51188643150958e.06 FALSE 529.6 Glossodynia Both 63 271 10 digestive chartreuse4 271, 63 68, 8 68, 15 67, 21 68, 19 0.285 0.156 0.0674 1.171 1.33 0.98 1.81 0.843 0.488 0.0845 1.073 2.32 0.892 6.05 1.13 0.457 0.0132 1.878 3.1 1.27 7.61 0.955 0.467 0.041 1.387 2.6 1.04 6.49 PRS_PLINK_2.51188643150958e.06 FALSE 530 Diseases of esophagus Both 4551 2565 10 digestive chartreuse4 2565, 4551 642, 1070 641, 1143 641, 1166 641, 1171 0.0354 0.0248 0.153 0.815 1.04 0.987 1.09 0.0604 0.0713 0.397 0.401 1.06 0.924 1.22 0.0844 0.0713 0.236 0.6266 1.09 0.946 1.25 0.0991 0.071 0.163 0.7875 1.1 0.961 1.27 PRS_PLINK_2.51188643150958e.06 FALSE 530.1 Esophagitis, GERD and related diseases Both 4431 2565 10 digestive chartreuse4 2565, 4431 642, 1035 641, 1110 641, 1138 641, 1147 0.0395 0.0249 0.113 0.9474 1.04 0.991 1.09 0.0653 0.0717 0.362 0.4408 1.07 0.928 1.23 0.0938 0.0717 0.191 0.7188 1.1 0.954 1.26 0.111 0.0714 0.119 0.9242 1.12 0.972 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 530.11 GERD Both 4298 2565 10 digestive chartreuse4 2565, 4298 642, 1005 641, 1079 641, 1102 641, 1111 0.0354 0.0251 0.157 0.8032 1.04 0.986 1.09 0.0677 0.0722 0.348 0.4579 1.07 0.929 1.23 0.09 0.0722 0.212 0.673 1.09 0.95 1.26 0.107 0.0719 0.135 0.8696 1.11 0.967 1.28 PRS_PLINK_2.51188643150958e.06 FALSE 530.12 Ulcer of esophagus Both 178 380 10 digestive chartreuse4 380, 178 95, 42 95, 35 95, 54 95, 47 0.0838 0.0986 0.395 0.4032 1.09 0.896 1.32 -0.194 0.279 0.486 0.3136 0.823 0.477 1.42 0.216 0.266 0.416 0.3809 1.24 0.737 2.09 0.153 0.27 0.57 0.2438 1.17 0.686 1.98 PRS_PLINK_2.51188643150958e.06 FALSE 530.13 Barrett's esophagus Both 226 793 10 digestive chartreuse4 793, 226 199, 50 198, 64 198, 58 198, 54 0.0664 0.08 0.406 0.3915 1.07 0.914 1.25 0.261 0.216 0.227 0.644 1.3 0.85 1.98 0.198 0.22 0.37 0.4321 1.22 0.791 1.88 0.117 0.223 0.599 0.2222 1.12 0.726 1.74 PRS_PLINK_2.51188643150958e.06 FALSE 530.14 Reflux esophagitis Both 853 1836 10 digestive chartreuse4 1836, 853 459, 195 459, 202 459, 222 459, 234 0.0627 0.0422 0.137 0.8628 1.06 0.98 1.16 0.0479 0.121 0.693 0.1595 1.05 0.827 1.33 0.125 0.12 0.295 0.53 1.13 0.897 1.43 0.178 0.118 0.132 0.8787 1.2 0.948 1.51 PRS_PLINK_2.51188643150958e.06 FALSE 530.15 Eosinophilic esophagitis Both 64 208 10 digestive chartreuse4 208, 64 52, 11 52, 12 52, 17 52, 24 0.326 0.177 0.0654 1.185 1.39 0.979 1.96 0.0481 0.469 0.918 0.03701 1.05 0.418 2.63 0.25 0.452 0.58 0.2363 1.28 0.529 3.12 0.815 0.429 0.0576 1.239 2.26 0.974 5.24 PRS_PLINK_2.51188643150958e.06 FALSE 530.2 Esophageal bleeding (varices/hemorrhage) Both 210 659 10 digestive chartreuse4 659, 210 165, 54 165, 49 164, 43 165, 64 0.0641 0.0833 0.442 0.3546 1.07 0.906 1.26 -0.0815 0.229 0.722 0.1413 0.922 0.588 1.44 -0.11 0.237 0.642 0.1925 0.895 0.562 1.43 0.202 0.221 0.359 0.4452 1.22 0.795 1.89 PRS_PLINK_2.51188643150958e.06 FALSE 530.3 Stricture and stenosis of esophagus Both 309 934 10 digestive chartreuse4 934, 309 234, 68 233, 88 233, 72 234, 81 0.0305 0.0656 0.641 0.1929 1.03 0.907 1.17 0.224 0.189 0.237 0.6253 1.25 0.863 1.81 0.0303 0.196 0.877 0.05704 1.03 0.702 1.51 0.182 0.19 0.338 0.4712 1.2 0.827 1.74 PRS_PLINK_2.51188643150958e.06 FALSE 530.5 Disorders of esophageal motility Both 223 560 10 digestive chartreuse4 560, 223 140, 65 140, 47 140, 56 140, 55 -0.0967 0.073 0.185 0.7322 0.908 0.787 1.05 -0.245 0.232 0.29 0.5373 0.783 0.497 1.23 -0.123 0.225 0.584 0.2337 0.884 0.569 1.37 -0.16 0.225 0.478 0.3203 0.853 0.548 1.33 PRS_PLINK_2.51188643150958e.06 FALSE 530.6 Diverticulum of esophagus, acquired Both 23 120 10 digestive chartreuse4 120, 23 30, 7 30, 5 30, 6 30, 5 0.0356 0.22 0.872 0.05969 1.04 0.673 1.6 -0.619 0.702 0.377 0.4233 0.538 0.136 2.13 -0.0831 0.619 0.893 0.04908 0.92 0.274 3.1 -0.366 0.634 0.563 0.2492 0.693 0.2 2.4 PRS_PLINK_2.51188643150958e.06 TRUE 530.7 Gastroesophageal laceration-hemorrhage syndrome Both 41 77 10 digestive chartreuse4 77, 41 20, 11 19, 8 19, 14 19, 8 0.0731 0.189 0.699 0.1558 1.08 0.743 1.56 -0.2 0.595 0.737 0.1326 0.819 0.255 2.63 0.448 0.574 0.435 0.361 1.57 0.508 4.83 -0.316 0.624 0.612 0.213 0.729 0.215 2.48 PRS_PLINK_2.51188643150958e.06 TRUE 530.9 Heartburn Both 580 1538 10 digestive chartreuse4 1538, 580 385, 124 384, 137 384, 177 385, 142 0.0683 0.0499 0.171 0.7674 1.07 0.971 1.18 0.127 0.144 0.38 0.4206 1.14 0.856 1.51 0.354 0.138 0.0105 1.981 1.43 1.09 1.87 0.134 0.144 0.353 0.4524 1.14 0.862 1.52 PRS_PLINK_2.51188643150958e.06 FALSE 531 Peptic ulcer (excl. esophageal) Both 815 3370 10 digestive chartreuse4 3370, 815 842, 200 842, 184 842, 215 843, 216 0.0209 0.0393 0.595 0.2253 1.02 0.945 1.1 -0.069 0.114 0.543 0.2652 0.933 0.747 1.17 0.065 0.11 0.555 0.2554 1.07 0.86 1.32 0.0793 0.111 0.473 0.3248 1.08 0.872 1.34 PRS_PLINK_2.51188643150958e.06 FALSE 531.1 Hemorrhage from gastrointestinal ulcer Both 169 636 10 digestive chartreuse4 636, 169 159, 42 159, 37 159, 44 159, 46 -0.0285 0.0809 0.724 0.1401 0.972 0.829 1.14 -0.106 0.252 0.673 0.1722 0.899 0.549 1.47 -0.00324 0.249 0.99 0.004547 0.997 0.612 1.62 0.105 0.244 0.667 0.1761 1.11 0.688 1.79 PRS_PLINK_2.51188643150958e.06 FALSE 531.2 Gastric ulcer Both 467 1975 10 digestive chartreuse4 1975, 467 493, 123 494, 110 493, 113 494, 121 -0.0176 0.0509 0.73 0.1367 0.983 0.889 1.09 -0.0872 0.146 0.551 0.2587 0.917 0.688 1.22 -0.108 0.146 0.459 0.3382 0.898 0.675 1.19 -0.0317 0.145 0.827 0.08274 0.969 0.73 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 531.3 Duodenal ulcer Both 202 749 10 digestive chartreuse4 749, 202 188, 44 187, 39 187, 59 187, 60 0.0877 0.0787 0.265 0.5765 1.09 0.936 1.27 -0.0482 0.245 0.844 0.07349 0.953 0.589 1.54 0.344 0.231 0.136 0.866 1.41 0.897 2.22 0.318 0.226 0.16 0.7955 1.37 0.882 2.14 PRS_PLINK_2.51188643150958e.06 FALSE 531.4 Peptic ulcer, site unspecified Both 359 1389 10 digestive chartreuse4 1389, 359 348, 98 347, 80 347, 91 347, 90 -0.0219 0.0574 0.702 0.1534 0.978 0.874 1.09 -0.178 0.17 0.295 0.5302 0.837 0.6 1.17 -0.0736 0.166 0.657 0.1824 0.929 0.671 1.29 -0.0517 0.167 0.756 0.1215 0.95 0.685 1.32 PRS_PLINK_2.51188643150958e.06 FALSE 531.5 Gastrojejunal ulcer Both 81 228 10 digestive chartreuse4 228, 81 57, 16 57, 23 57, 18 57, 24 0.0977 0.129 0.448 0.349 1.1 0.857 1.42 0.451 0.397 0.256 0.5925 1.57 0.722 3.41 0.00332 0.424 0.994 0.002722 1 0.437 2.3 0.506 0.388 0.193 0.7153 1.66 0.775 3.55 PRS_PLINK_2.51188643150958e.06 FALSE 532 Dysphagia Both 1791 2502 10 digestive chartreuse4 2502, 1791 626, 433 625, 474 625, 437 626, 446 0.027 0.032 0.399 0.3993 1.03 0.965 1.09 0.0993 0.0895 0.267 0.5728 1.1 0.927 1.32 0.0188 0.0908 0.836 0.07765 1.02 0.853 1.22 0.03 0.0899 0.738 0.1318 1.03 0.864 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 535 Gastritis and duodenitis Both 1146 3622 10 digestive chartreuse4 3622, 1146 906, 275 905, 275 905, 310 906, 286 0.00975 0.0343 0.776 0.1101 1.01 0.944 1.08 0.00455 0.0977 0.963 0.01643 1 0.829 1.22 0.13 0.0959 0.175 0.757 1.14 0.944 1.37 0.0487 0.0974 0.617 0.2097 1.05 0.867 1.27 PRS_PLINK_2.51188643150958e.06 FALSE 535.1 Acute gastritis Both 448 1613 10 digestive chartreuse4 1613, 448 404, 122 403, 115 404, 103 402, 108 -0.0513 0.052 0.324 0.4896 0.95 0.858 1.05 -0.0436 0.15 0.771 0.1131 0.957 0.714 1.28 -0.189 0.153 0.218 0.6613 0.828 0.613 1.12 -0.11 0.153 0.473 0.3248 0.896 0.664 1.21 PRS_PLINK_2.51188643150958e.06 FALSE 535.2 Atrophic gastritis Both 179 448 10 digestive chartreuse4 448, 179 112, 40 112, 33 112, 58 112, 48 0.0134 0.0961 0.889 0.051 1.01 0.839 1.22 -0.247 0.278 0.375 0.4263 0.782 0.453 1.35 0.385 0.253 0.129 0.8909 1.47 0.895 2.41 0.0363 0.263 0.89 0.05059 1.04 0.62 1.74 PRS_PLINK_2.51188643150958e.06 FALSE 535.6 Duodenitis Both 154 462 10 digestive chartreuse4 462, 154 116, 32 115, 41 115, 46 116, 35 0.0498 0.091 0.584 0.2334 1.05 0.879 1.26 0.295 0.278 0.29 0.5383 1.34 0.778 2.32 0.392 0.268 0.144 0.8414 1.48 0.875 2.5 0.00603 0.285 0.983 0.007383 1.01 0.575 1.76 PRS_PLINK_2.51188643150958e.06 FALSE 535.8 Other specified gastritis Both 330 898 10 digestive chartreuse4 898, 330 225, 83 224, 91 224, 90 225, 66 -0.0659 0.067 0.325 0.488 0.936 0.821 1.07 0.13 0.182 0.474 0.3242 1.14 0.798 1.63 0.127 0.182 0.486 0.3133 1.14 0.794 1.62 -0.235 0.195 0.228 0.6418 0.791 0.54 1.16 PRS_PLINK_2.51188643150958e.06 FALSE 535.9 Gastritis and duodenitis, NOS Both 564 1723 10 digestive chartreuse4 1723, 564 431, 133 431, 134 430, 158 431, 139 0.00428 0.0474 0.928 0.0324 1 0.915 1.1 0.033 0.141 0.815 0.08893 1.03 0.784 1.36 0.193 0.137 0.159 0.7982 1.21 0.927 1.59 0.057 0.14 0.683 0.1654 1.06 0.805 1.39 PRS_PLINK_2.51188643150958e.06 FALSE 536 Disorders of function of stomach Both 1221 3639 10 digestive chartreuse4 3639, 1221 910, 298 910, 298 909, 342 910, 283 0.00604 0.0331 0.855 0.06802 1.01 0.943 1.07 0.0109 0.0947 0.908 0.04171 1.01 0.84 1.22 0.141 0.0925 0.128 0.8931 1.15 0.96 1.38 -0.0447 0.0963 0.642 0.1922 0.956 0.792 1.15 PRS_PLINK_2.51188643150958e.06 FALSE 536.3 Gastroparesis Both 337 1008 10 digestive chartreuse4 1008, 337 252, 92 252, 78 252, 87 252, 80 -0.00282 0.0633 0.964 0.01571 0.997 0.881 1.13 -0.129 0.18 0.475 0.3234 0.879 0.618 1.25 -0.0708 0.177 0.689 0.1619 0.932 0.659 1.32 -0.128 0.181 0.48 0.319 0.88 0.618 1.25 PRS_PLINK_2.51188643150958e.06 FALSE 536.7 Complications of gastrostomy, colostomy and enterostomy Both 158 498 10 digestive chartreuse4 498, 158 125, 44 124, 33 124, 50 125, 31 -0.0108 0.0928 0.907 0.04231 0.989 0.825 1.19 -0.365 0.278 0.19 0.7212 0.695 0.403 1.2 0.147 0.252 0.56 0.252 1.16 0.707 1.9 -0.325 0.272 0.232 0.6349 0.723 0.424 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 536.8 Dyspepsia and other specified disorders of function of stomach Both 927 2822 10 digestive chartreuse4 2822, 927 706, 224 705, 242 705, 254 706, 207 -0.015 0.0382 0.693 0.159 0.985 0.914 1.06 0.0957 0.108 0.374 0.427 1.1 0.891 1.36 0.116 0.107 0.274 0.5615 1.12 0.912 1.38 -0.0822 0.111 0.46 0.3371 0.921 0.741 1.15 PRS_PLINK_2.51188643150958e.06 FALSE 537 Other disorders of stomach and duodenum Both 1402 3998 10 digestive chartreuse4 3998, 1402 1000, 320 999, 325 999, 385 1000, 371 0.0721 0.0324 0.0259 1.586 1.07 1.01 1.15 0.0263 0.0909 0.773 0.1121 1.03 0.859 1.23 0.199 0.0885 0.0248 1.605 1.22 1.03 1.45 0.139 0.0893 0.119 0.9233 1.15 0.965 1.37 PRS_PLINK_2.51188643150958e.06 FALSE 537.1 Lesions of stomach and duodenum Both 84 237 10 digestive chartreuse4 237, 84 60, 18 59, 17 59, 23 59, 26 0.146 0.133 0.272 0.5655 1.16 0.892 1.5 -0.0976 0.389 0.802 0.09575 0.907 0.423 1.95 0.246 0.385 0.523 0.2813 1.28 0.601 2.72 0.371 0.366 0.311 0.5075 1.45 0.707 2.97 PRS_PLINK_2.51188643150958e.06 FALSE 539 Bariatric surgery Both 852 2374 10 digestive chartreuse4 2374, 852 594, 219 593, 201 593, 187 594, 245 -0.0287 0.0403 0.476 0.3221 0.972 0.898 1.05 -0.0891 0.117 0.447 0.35 0.915 0.727 1.15 -0.154 0.118 0.192 0.7177 0.857 0.68 1.08 0.0929 0.112 0.409 0.3886 1.1 0.88 1.37 PRS_PLINK_2.51188643150958e.06 FALSE 540 Appendiceal conditions Both 158 773 10 digestive chartreuse4 773, 158 194, 39 193, 37 193, 34 193, 48 0.13 0.0923 0.16 0.7952 1.14 0.95 1.36 -0.00772 0.256 0.976 0.01057 0.992 0.601 1.64 -0.0592 0.26 0.82 0.08642 0.942 0.567 1.57 0.206 0.241 0.393 0.4054 1.23 0.766 1.97 PRS_PLINK_2.51188643150958e.06 FALSE 540.1 Appendicitis Both 140 660 10 digestive chartreuse4 660, 140 165, 37 165, 30 165, 29 165, 44 0.128 0.0985 0.194 0.7124 1.14 0.937 1.38 -0.187 0.272 0.491 0.309 0.829 0.486 1.41 -0.174 0.273 0.523 0.2816 0.84 0.492 1.43 0.23 0.255 0.368 0.4346 1.26 0.763 2.07 PRS_PLINK_2.51188643150958e.06 FALSE 540.11 Acute appendicitis Both 121 551 10 digestive chartreuse4 551, 121 138, 31 138, 30 137, 24 138, 36 0.116 0.103 0.259 0.5866 1.12 0.918 1.37 0.00057 0.295 0.998 0.000671 1 0.562 1.78 -0.178 0.306 0.561 0.251 0.837 0.46 1.52 0.198 0.285 0.487 0.3121 1.22 0.697 2.13 PRS_PLINK_2.51188643150958e.06 FALSE 550 Abdominal hernia Both 2054 5201 10 digestive chartreuse4 5201, 2054 1300, 482 1300, 534 1300, 531 1300, 507 0.0178 0.0266 0.502 0.2991 1.02 0.966 1.07 0.0975 0.0752 0.195 0.7105 1.1 0.951 1.28 0.1 0.0751 0.181 0.7414 1.11 0.954 1.28 0.063 0.0761 0.408 0.3897 1.07 0.917 1.24 PRS_PLINK_2.51188643150958e.06 FALSE 550.1 Inguinal hernia Both 454 2181 10 digestive chartreuse4 2181, 454 545, 110 545, 134 545, 97 545, 113 -0.00693 0.0515 0.893 0.04916 0.993 0.898 1.1 0.174 0.143 0.223 0.6525 1.19 0.9 1.58 -0.158 0.153 0.304 0.5169 0.854 0.632 1.15 -0.00701 0.149 0.963 0.01658 0.993 0.741 1.33 PRS_PLINK_2.51188643150958e.06 FALSE 550.2 Diaphragmatic hernia Both 1014 3841 10 digestive chartreuse4 3841, 1014 960, 233 960, 264 960, 263 960, 254 0.0345 0.0358 0.335 0.4752 1.04 0.965 1.11 0.119 0.101 0.24 0.6205 1.13 0.924 1.37 0.125 0.101 0.218 0.6609 1.13 0.929 1.38 0.0955 0.102 0.349 0.4567 1.1 0.901 1.34 PRS_PLINK_2.51188643150958e.06 FALSE 550.3 Femoral hernia Both 54 179 10 digestive chartreuse4 179, 54 45, 13 45, 13 44, 13 45, 15 -0.0333 0.14 0.813 0.09008 0.967 0.735 1.27 0.183 0.464 0.693 0.1592 1.2 0.484 2.98 0.183 0.484 0.705 0.1517 1.2 0.465 3.1 0.0536 0.441 0.903 0.04417 1.06 0.445 2.5 PRS_PLINK_2.51188643150958e.06 FALSE 550.4 Umbilical hernia Both 393 1760 10 digestive chartreuse4 1760, 393 440, 93 440, 95 440, 109 440, 96 0.0317 0.0556 0.569 0.2448 1.03 0.926 1.15 0.0345 0.161 0.83 0.08082 1.04 0.755 1.42 0.156 0.157 0.32 0.4947 1.17 0.86 1.59 0.0299 0.161 0.853 0.0693 1.03 0.751 1.41 PRS_PLINK_2.51188643150958e.06 FALSE 550.5 Ventral hernia Both 729 3159 10 digestive chartreuse4 3159, 729 790, 195 790, 181 789, 180 790, 173 -0.0308 0.04 0.441 0.3551 0.97 0.897 1.05 -0.0613 0.115 0.594 0.2259 0.941 0.751 1.18 -0.0568 0.116 0.623 0.2056 0.945 0.753 1.18 -0.108 0.117 0.356 0.4484 0.898 0.715 1.13 PRS_PLINK_2.51188643150958e.06 FALSE 550.6 Incisional hernia Both 443 1912 10 digestive chartreuse4 1912, 443 478, 111 478, 113 478, 116 478, 103 0.0207 0.0523 0.692 0.16 1.02 0.922 1.13 0.018 0.148 0.903 0.04415 1.02 0.761 1.36 0.0484 0.149 0.745 0.1281 1.05 0.784 1.4 -0.0725 0.152 0.633 0.1989 0.93 0.691 1.25 PRS_PLINK_2.51188643150958e.06 FALSE 555 Inflammatory bowel disease and other gastroenteritis and colitis Both 706 1054 10 digestive chartreuse4 1054, 706 264, 164 263, 176 263, 167 264, 199 0.113 0.0504 0.0252 1.599 1.12 1.01 1.24 0.0823 0.142 0.563 0.2494 1.09 0.821 1.44 0.0347 0.143 0.808 0.09233 1.04 0.782 1.37 0.26 0.141 0.0651 1.186 1.3 0.984 1.71 PRS_PLINK_2.51188643150958e.06 FALSE 555.1 Regional enteritis Both 510 594 10 digestive chartreuse4 594, 510 149, 110 148, 125 148, 118 149, 157 0.167 0.0634 0.00827 2.082 1.18 1.04 1.34 0.204 0.183 0.265 0.5775 1.23 0.857 1.76 0.175 0.185 0.343 0.4649 1.19 0.83 1.71 0.393 0.177 0.0263 1.581 1.48 1.05 2.1 PRS_PLINK_2.51188643150958e.06 FALSE 555.2 Ulcerative colitis Both 414 651 10 digestive chartreuse4 651, 414 163, 92 163, 104 162, 92 163, 126 0.183 0.0676 0.00687 2.163 1.2 1.05 1.37 0.118 0.184 0.521 0.283 1.13 0.784 1.61 0.0235 0.19 0.902 0.04503 1.02 0.706 1.49 0.361 0.181 0.0466 1.331 1.43 1.01 2.05 PRS_PLINK_2.51188643150958e.06 FALSE 555.21 Ulcerative colitis (chronic) Both 266 365 10 digestive chartreuse4 365, 266 92, 62 91, 65 91, 52 91, 87 0.201 0.087 0.0207 1.684 1.22 1.03 1.45 0.0231 0.237 0.922 0.03508 1.02 0.643 1.63 -0.217 0.25 0.385 0.4142 0.805 0.494 1.31 0.282 0.232 0.224 0.6501 1.33 0.842 2.09 PRS_PLINK_2.51188643150958e.06 FALSE 556 Ulceration of the lower GI tract Both 339 522 10 digestive chartreuse4 522, 339 131, 87 130, 92 130, 74 131, 86 0.000906 0.0694 0.99 0.004548 1 0.874 1.15 0.0655 0.198 0.741 0.1302 1.07 0.724 1.57 -0.183 0.205 0.372 0.4295 0.832 0.556 1.25 -0.0269 0.203 0.895 0.04831 0.973 0.654 1.45 PRS_PLINK_2.51188643150958e.06 FALSE 556.1 Ulceration of intestine Both 306 455 10 digestive chartreuse4 455, 306 114, 75 114, 88 113, 69 114, 74 -0.000887 0.0755 0.991 0.004093 0.999 0.862 1.16 0.161 0.21 0.442 0.3543 1.18 0.779 1.77 -0.114 0.218 0.601 0.2208 0.892 0.582 1.37 -0.0224 0.218 0.918 0.0371 0.978 0.638 1.5 PRS_PLINK_2.51188643150958e.06 FALSE 556.11 Angiodysplasia of intestine (without mention of hemorrhage) Both 122 192 10 digestive chartreuse4 192, 122 48, 33 48, 35 48, 22 48, 32 -0.00532 0.125 0.966 0.01504 0.995 0.779 1.27 0.0731 0.338 0.829 0.08153 1.08 0.554 2.09 -0.473 0.365 0.195 0.7091 0.623 0.304 1.28 -0.126 0.352 0.72 0.1425 0.882 0.443 1.76 PRS_PLINK_2.51188643150958e.06 FALSE 557 Intestinal malabsorption (non-celiac) Both 974 1271 10 digestive chartreuse4 1271, 974 318, 259 318, 251 317, 216 318, 248 0.0139 0.042 0.74 0.1308 1.01 0.934 1.1 0.00208 0.121 0.986 0.005989 1 0.79 1.27 -0.167 0.123 0.177 0.7526 0.847 0.665 1.08 -0.0339 0.122 0.781 0.1074 0.967 0.761 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 557.1 Celiac disease Both 171 334 10 digestive chartreuse4 334, 171 84, 48 83, 38 83, 48 84, 37 -0.059 0.0995 0.553 0.2571 0.943 0.776 1.15 -0.233 0.277 0.401 0.3969 0.792 0.46 1.36 -0.0403 0.266 0.88 0.05566 0.961 0.57 1.62 -0.249 0.277 0.368 0.4339 0.779 0.453 1.34 PRS_PLINK_2.51188643150958e.06 FALSE 558 Noninfectious gastroenteritis Both 1523 1886 10 digestive chartreuse4 1886, 1523 472, 369 471, 419 471, 346 472, 389 0.0246 0.0346 0.476 0.3221 1.02 0.958 1.1 0.141 0.0976 0.149 0.8276 1.15 0.951 1.39 -0.0532 0.101 0.597 0.2244 0.948 0.779 1.15 0.0791 0.0988 0.423 0.3734 1.08 0.892 1.31 PRS_PLINK_2.51188643150958e.06 FALSE 559 Ileostomy status Both 383 658 10 digestive chartreuse4 658, 383 165, 91 164, 86 164, 91 165, 115 0.15 0.0653 0.0218 1.662 1.16 1.02 1.32 0.0117 0.191 0.951 0.02171 1.01 0.696 1.47 0.0408 0.191 0.831 0.08053 1.04 0.717 1.51 0.298 0.186 0.108 0.9659 1.35 0.936 1.94 PRS_PLINK_2.51188643150958e.06 FALSE 560 Intestinal obstruction without mention of hernia Both 1160 1796 10 digestive chartreuse4 1796, 1160 449, 289 449, 280 449, 292 449, 299 0.0647 0.0382 0.0905 1.043 1.07 0.99 1.15 -0.0282 0.109 0.795 0.09973 0.972 0.786 1.2 -0.000329 0.108 0.998 0.001061 1 0.81 1.23 0.0515 0.108 0.633 0.1985 1.05 0.852 1.3 PRS_PLINK_2.51188643150958e.06 FALSE 560.1 Paralytic ileus Both 538 1145 10 digestive chartreuse4 1145, 538 287, 150 286, 136 286, 125 286, 127 -0.0221 0.0527 0.675 0.171 0.978 0.882 1.08 -0.0681 0.147 0.643 0.1916 0.934 0.7 1.25 -0.199 0.149 0.182 0.7392 0.82 0.612 1.1 -0.123 0.149 0.411 0.3866 0.884 0.66 1.18 PRS_PLINK_2.51188643150958e.06 FALSE 560.2 Impaction of intestine Both 177 307 10 digestive chartreuse4 307, 177 77, 40 77, 54 76, 44 77, 39 0.0968 0.109 0.374 0.4273 1.1 0.89 1.36 0.322 0.274 0.241 0.6182 1.38 0.806 2.36 0.147 0.28 0.6 0.2219 1.16 0.669 2.01 -0.0117 0.293 0.968 0.014 0.988 0.556 1.76 PRS_PLINK_2.51188643150958e.06 FALSE 560.3 Peritoneal or intestinal adhesions Both 120 207 10 digestive chartreuse4 207, 120 52, 31 52, 27 51, 34 52, 28 0.0873 0.116 0.452 0.3451 1.09 0.869 1.37 -0.0254 0.341 0.941 0.02653 0.975 0.5 1.9 0.158 0.335 0.637 0.196 1.17 0.608 2.26 0.293 0.367 0.424 0.3727 1.34 0.653 2.75 PRS_PLINK_2.51188643150958e.06 FALSE 560.4 Other intestinal obstruction Both 754 1192 10 digestive chartreuse4 1192, 754 298, 180 298, 173 298, 199 298, 202 0.117 0.0476 0.0144 1.84 1.12 1.02 1.23 0.00318 0.137 0.981 0.008131 1 0.768 1.31 0.107 0.134 0.421 0.3754 1.11 0.857 1.45 0.172 0.135 0.202 0.6939 1.19 0.912 1.55 PRS_PLINK_2.51188643150958e.06 FALSE 561 Symptoms involving digestive system Both 1079 1672 10 digestive chartreuse4 1672, 1079 418, 282 418, 275 418, 262 418, 260 -0.0131 0.0394 0.74 0.1307 0.987 0.914 1.07 -0.031 0.112 0.781 0.1072 0.969 0.779 1.21 -0.0835 0.112 0.455 0.3416 0.92 0.739 1.15 -0.0449 0.113 0.691 0.1606 0.956 0.766 1.19 PRS_PLINK_2.51188643150958e.06 FALSE 562 Diverticulosis and diverticulitis Both 2146 1789 10 digestive chartreuse4 1789, 2146 448, 501 447, 595 447, 524 447, 525 0.037 0.0343 0.281 0.551 1.04 0.97 1.11 0.169 0.096 0.0779 1.108 1.18 0.981 1.43 0.051 0.0972 0.6 0.222 1.05 0.87 1.27 0.0585 0.0966 0.544 0.264 1.06 0.877 1.28 PRS_PLINK_2.51188643150958e.06 FALSE 562.1 Diverticulosis Both 2123 1785 10 digestive chartreuse4 1785, 2123 447, 499 446, 586 446, 518 446, 519 0.0349 0.0345 0.311 0.5072 1.04 0.968 1.11 0.159 0.0963 0.098 1.009 1.17 0.971 1.42 0.0428 0.0975 0.661 0.18 1.04 0.862 1.26 0.0495 0.0967 0.609 0.2154 1.05 0.869 1.27 PRS_PLINK_2.51188643150958e.06 FALSE 562.2 Diverticulitis Both 491 1206 10 digestive chartreuse4 1206, 491 302, 98 301, 146 301, 130 302, 117 0.0703 0.0565 0.213 0.6706 1.07 0.96 1.2 0.396 0.157 0.0117 1.932 1.49 1.09 2.02 0.278 0.159 0.0801 1.096 1.32 0.967 1.8 0.172 0.163 0.293 0.5339 1.19 0.862 1.64 PRS_PLINK_2.51188643150958e.06 FALSE 564 Functional digestive disorders Both 3711 2001 10 digestive chartreuse4 2001, 3711 501, 899 500, 966 500, 896 500, 949 0.0357 0.0278 0.198 0.7032 1.04 0.981 1.09 0.0661 0.0796 0.406 0.3914 1.07 0.914 1.25 -0.00648 0.0802 0.936 0.02892 0.994 0.849 1.16 0.0738 0.0797 0.355 0.4501 1.08 0.921 1.26 PRS_PLINK_2.51188643150958e.06 FALSE 564.1 Irritable Bowel Syndrome Both 1250 1652 10 digestive chartreuse4 1652, 1250 413, 319 413, 322 413, 313 413, 296 -0.0244 0.0372 0.512 0.2907 0.976 0.907 1.05 -0.00549 0.107 0.959 0.01812 0.995 0.806 1.23 -0.0125 0.107 0.907 0.04227 0.988 0.8 1.22 -0.057 0.109 0.601 0.221 0.945 0.763 1.17 PRS_PLINK_2.51188643150958e.06 FALSE 564.9 Personal history of diseases of digestive system Both 1105 1859 10 digestive chartreuse4 1859, 1105 465, 269 465, 281 464, 255 465, 300 0.0331 0.0377 0.38 0.4208 1.03 0.96 1.11 0.0595 0.109 0.585 0.233 1.06 0.857 1.31 -0.0624 0.111 0.574 0.2413 0.94 0.756 1.17 0.139 0.108 0.198 0.7041 1.15 0.93 1.42 PRS_PLINK_2.51188643150958e.06 FALSE 565 Anal and rectal conditions Both 1231 3432 10 digestive chartreuse4 3432, 1231 858, 312 858, 312 858, 294 858, 312 0.00823 0.0331 0.804 0.09498 1.01 0.945 1.08 0.0181 0.0938 0.847 0.07195 1.02 0.847 1.22 -0.0492 0.095 0.605 0.2184 0.952 0.79 1.15 0.0155 0.0944 0.869 0.0609 1.02 0.844 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 565.1 Anal and rectal polyp Both 479 1592 10 digestive chartreuse4 1592, 479 398, 122 398, 132 398, 109 398, 115 -0.00992 0.0519 0.848 0.07138 0.99 0.894 1.1 0.1 0.145 0.49 0.31 1.11 0.832 1.47 -0.117 0.15 0.434 0.362 0.89 0.663 1.19 -0.037 0.149 0.804 0.09474 0.964 0.719 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 567 Peritonitis and retroperitoneal infections Both 532 1456 10 digestive chartreuse4 1456, 532 364, 135 364, 114 364, 149 364, 134 0.0644 0.0543 0.236 0.6264 1.07 0.959 1.19 -0.14 0.149 0.346 0.4606 0.869 0.649 1.16 0.167 0.143 0.245 0.6102 1.18 0.892 1.56 0.00574 0.146 0.969 0.01387 1.01 0.756 1.34 PRS_PLINK_2.51188643150958e.06 FALSE 568 Other disorders of peritoneum Both 543 1865 10 digestive chartreuse4 1865, 543 467, 126 466, 129 466, 145 466, 143 0.127 0.0516 0.0137 1.864 1.14 1.03 1.26 0.0582 0.142 0.683 0.1657 1.06 0.802 1.4 0.183 0.14 0.192 0.7159 1.2 0.912 1.58 0.158 0.14 0.26 0.5858 1.17 0.89 1.54 PRS_PLINK_2.51188643150958e.06 FALSE 568.1 Peritoneal adhesions (postoperative) (postinfection) Both 381 1389 10 digestive chartreuse4 1389, 381 348, 85 347, 95 347, 93 347, 108 0.14 0.0597 0.0193 1.715 1.15 1.02 1.29 0.155 0.169 0.361 0.4425 1.17 0.838 1.63 0.149 0.171 0.381 0.4186 1.16 0.831 1.62 0.274 0.166 0.0982 1.008 1.32 0.95 1.82 PRS_PLINK_2.51188643150958e.06 FALSE 569 Other disorders of intestine Both 2969 3816 10 digestive chartreuse4 3816, 2969 954, 703 954, 735 954, 786 954, 744 0.0264 0.0246 0.284 0.5472 1.03 0.978 1.08 0.0432 0.0703 0.539 0.2686 1.04 0.91 1.2 0.107 0.0696 0.124 0.9077 1.11 0.971 1.28 0.0522 0.0703 0.458 0.3395 1.05 0.918 1.21 PRS_PLINK_2.51188643150958e.06 FALSE 569.1 Toxic gastroenteritis and colitis Both 127 364 10 digestive chartreuse4 364, 127 91, 23 91, 31 91, 48 91, 25 0.0454 0.104 0.662 0.1794 1.05 0.854 1.28 0.245 0.313 0.433 0.3631 1.28 0.692 2.36 0.62 0.297 0.0369 1.433 1.86 1.04 3.33 0.159 0.331 0.631 0.1999 1.17 0.612 2.24 PRS_PLINK_2.51188643150958e.06 FALSE 569.2 Gastrointestinal complications Both 651 1505 10 digestive chartreuse4 1505, 651 377, 170 376, 137 376, 181 376, 163 0.05 0.0492 0.31 0.509 1.05 0.955 1.16 -0.161 0.138 0.245 0.6113 0.852 0.65 1.12 0.106 0.131 0.42 0.3767 1.11 0.859 1.44 -0.00895 0.135 0.947 0.02361 0.991 0.761 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 571 Chronic liver disease and cirrhosis Both 1559 3594 10 digestive chartreuse4 3594, 1559 899, 380 898, 380 898, 381 899, 418 0.025 0.0305 0.412 0.3847 1.03 0.966 1.09 -0.00298 0.0867 0.973 0.01208 0.997 0.841 1.18 0.00705 0.0869 0.935 0.02902 1.01 0.849 1.19 0.0876 0.0859 0.308 0.5117 1.09 0.922 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 571.5 Other chronic nonalcoholic liver disease Both 1474 3565 10 digestive chartreuse4 3565, 1474 892, 355 891, 361 891, 359 891, 399 0.0247 0.0311 0.427 0.3701 1.03 0.964 1.09 0.0129 0.0886 0.884 0.05354 1.01 0.851 1.21 0.0123 0.0891 0.89 0.05054 1.01 0.85 1.21 0.109 0.0878 0.214 0.6704 1.12 0.939 1.32 PRS_PLINK_2.51188643150958e.06 FALSE 571.51 Cirrhosis of liver without mention of alcohol Both 325 1215 10 digestive chartreuse4 1215, 325 304, 80 304, 72 303, 77 304, 96 0.0332 0.0614 0.588 0.2304 1.03 0.917 1.17 -0.0945 0.183 0.605 0.2182 0.91 0.636 1.3 -0.0311 0.18 0.863 0.06408 0.969 0.682 1.38 0.232 0.176 0.187 0.7283 1.26 0.894 1.78 PRS_PLINK_2.51188643150958e.06 FALSE 571.6 Primary biliary cirrhosis Both 79 216 10 digestive chartreuse4 216, 79 54, 22 54, 18 54, 17 54, 22 -0.101 0.133 0.447 0.3502 0.904 0.696 1.17 -0.361 0.407 0.376 0.425 0.697 0.314 1.55 -0.346 0.4 0.387 0.4124 0.708 0.323 1.55 0.0159 0.389 0.967 0.01437 1.02 0.474 2.18 PRS_PLINK_2.51188643150958e.06 FALSE 571.8 Liver abscess and sequelae of chronic liver disease Both 322 1115 10 digestive chartreuse4 1115, 322 279, 90 279, 83 278, 72 279, 77 -0.00594 0.0631 0.925 0.03385 0.994 0.878 1.12 -0.0623 0.177 0.725 0.1398 0.94 0.664 1.33 -0.163 0.182 0.371 0.4308 0.85 0.595 1.21 -0.114 0.181 0.529 0.2763 0.892 0.626 1.27 PRS_PLINK_2.51188643150958e.06 FALSE 571.81 Portal hypertension Both 189 670 10 digestive chartreuse4 670, 189 168, 49 167, 46 167, 45 168, 49 0.0438 0.0857 0.61 0.2149 1.04 0.883 1.24 -0.0776 0.236 0.742 0.1295 0.925 0.583 1.47 -0.0296 0.239 0.901 0.04508 0.971 0.608 1.55 0.0867 0.235 0.712 0.1474 1.09 0.688 1.73 PRS_PLINK_2.51188643150958e.06 FALSE 572 Ascites (non malignant) Both 781 2594 10 digestive chartreuse4 2594, 781 649, 193 648, 187 648, 211 649, 190 0.0357 0.0417 0.391 0.4076 1.04 0.955 1.12 0.00424 0.118 0.971 0.01267 1 0.798 1.26 0.0983 0.115 0.391 0.4073 1.1 0.881 1.38 0.000939 0.118 0.994 0.002768 1 0.794 1.26 PRS_PLINK_2.51188643150958e.06 FALSE 573 Other disorders of liver Both 1836 3723 10 digestive chartreuse4 3723, 1836 931, 468 931, 442 930, 442 931, 484 0.00297 0.0282 0.916 0.03793 1 0.949 1.06 -0.0645 0.0812 0.427 0.3699 0.937 0.8 1.1 -0.0569 0.0814 0.485 0.3146 0.945 0.805 1.11 0.0344 0.0804 0.669 0.1745 1.03 0.884 1.21 PRS_PLINK_2.51188643150958e.06 FALSE 573.1 Chronic passive congestion of liver Both 56 147 10 digestive chartreuse4 147, 56 37, 17 37, 11 36, 13 37, 15 -0.0275 0.142 0.847 0.07235 0.973 0.737 1.29 -0.381 0.485 0.432 0.3641 0.683 0.264 1.77 -0.0955 0.465 0.837 0.0772 0.909 0.365 2.26 -0.0282 0.467 0.952 0.0214 0.972 0.389 2.43 PRS_PLINK_2.51188643150958e.06 FALSE 573.2 Liver replaced by transplant Both 110 319 10 digestive chartreuse4 319, 110 80, 24 80, 31 79, 28 80, 27 0.0767 0.12 0.523 0.2817 1.08 0.853 1.37 0.515 0.344 0.135 0.8693 1.67 0.852 3.29 0.298 0.343 0.385 0.414 1.35 0.688 2.64 0.261 0.335 0.436 0.3602 1.3 0.673 2.51 PRS_PLINK_2.51188643150958e.06 FALSE 573.3 Hepatomegaly Both 139 568 10 digestive chartreuse4 568, 139 142, 35 142, 41 142, 35 142, 28 -0.0344 0.0971 0.723 0.1407 0.966 0.799 1.17 0.112 0.265 0.671 0.1735 1.12 0.666 1.88 -0.00942 0.273 0.972 0.01212 0.991 0.58 1.69 -0.222 0.283 0.434 0.3629 0.801 0.46 1.4 PRS_PLINK_2.51188643150958e.06 FALSE 573.4 Acute and subacute necrosis of liver Both 119 356 10 digestive chartreuse4 356, 119 89, 28 89, 29 89, 28 89, 34 0.0729 0.11 0.507 0.2951 1.08 0.867 1.33 0.254 0.323 0.431 0.3654 1.29 0.685 2.43 0.0786 0.316 0.804 0.09493 1.08 0.582 2.01 0.269 0.312 0.388 0.4112 1.31 0.71 2.41 PRS_PLINK_2.51188643150958e.06 FALSE 573.5 Jaundice (not of newborn) Both 331 1089 10 digestive chartreuse4 1089, 331 273, 80 272, 79 272, 83 272, 89 0.0385 0.063 0.541 0.2667 1.04 0.919 1.18 0.00912 0.181 0.96 0.01777 1.01 0.707 1.44 0.095 0.182 0.602 0.2205 1.1 0.77 1.57 0.143 0.178 0.423 0.374 1.15 0.814 1.64 PRS_PLINK_2.51188643150958e.06 FALSE 573.6 Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH] Both 1034 2977 10 digestive chartreuse4 2977, 1034 745, 250 744, 259 744, 248 744, 276 0.0454 0.0365 0.213 0.6715 1.05 0.974 1.12 0.0446 0.103 0.665 0.1772 1.05 0.855 1.28 0.0064 0.104 0.951 0.02186 1.01 0.821 1.23 0.112 0.102 0.272 0.5649 1.12 0.916 1.37 PRS_PLINK_2.51188643150958e.06 FALSE 573.7 Abnormal results of function study of liver Both 1218 3138 10 digestive chartreuse4 3138, 1218 785, 298 784, 268 784, 307 785, 344 0.042 0.034 0.217 0.6638 1.04 0.976 1.11 -0.0971 0.0983 0.324 0.4901 0.907 0.748 1.1 0.043 0.0962 0.655 0.1836 1.04 0.864 1.26 0.149 0.0945 0.114 0.9417 1.16 0.965 1.4 PRS_PLINK_2.51188643150958e.06 FALSE 573.9 Abnormal serum enzyme levels Both 1783 3711 10 digestive chartreuse4 3711, 1783 928, 443 928, 420 927, 439 928, 480 0.0287 0.0289 0.321 0.493 1.03 0.972 1.09 -0.0555 0.0828 0.502 0.2989 0.946 0.804 1.11 -0.00157 0.0823 0.985 0.006666 0.998 0.85 1.17 0.0881 0.0812 0.278 0.556 1.09 0.931 1.28 PRS_PLINK_2.51188643150958e.06 FALSE 574 Cholelithiasis and cholecystitis Both 1080 4748 10 digestive chartreuse4 4748, 1080 1187, 265 1187, 274 1187, 281 1187, 260 0.0262 0.0341 0.442 0.3545 1.03 0.96 1.1 0.0464 0.0958 0.628 0.2019 1.05 0.868 1.26 0.0692 0.0951 0.467 0.3306 1.07 0.889 1.29 -0.0201 0.0969 0.836 0.07801 0.98 0.81 1.19 PRS_PLINK_2.51188643150958e.06 FALSE 574.1 Cholelithiasis Both 994 4458 10 digestive chartreuse4 4458, 994 1115, 247 1114, 246 1114, 258 1115, 243 0.032 0.0356 0.369 0.4331 1.03 0.963 1.11 0.0101 0.0999 0.92 0.03631 1.01 0.83 1.23 0.056 0.0987 0.57 0.2438 1.06 0.872 1.28 -0.0136 0.1 0.893 0.04938 0.987 0.81 1.2 PRS_PLINK_2.51188643150958e.06 FALSE 574.11 Cholelithiasis with acute cholecystitis Both 133 560 10 digestive chartreuse4 560, 133 140, 27 140, 39 140, 29 140, 38 0.00539 0.109 0.961 0.01742 1.01 0.811 1.25 0.479 0.283 0.091 1.041 1.61 0.926 2.81 0.0736 0.294 0.802 0.09572 1.08 0.605 1.91 0.297 0.288 0.302 0.5202 1.35 0.765 2.37 PRS_PLINK_2.51188643150958e.06 FALSE 574.12 Cholelithiasis with other cholecystitis Both 176 840 10 digestive chartreuse4 840, 176 210, 46 210, 43 210, 51 210, 36 -0.00146 0.0907 0.987 0.005596 0.999 0.836 1.19 0.0364 0.236 0.878 0.05674 1.04 0.653 1.65 0.159 0.229 0.487 0.3124 1.17 0.748 1.84 -0.177 0.244 0.468 0.3297 0.838 0.519 1.35 PRS_PLINK_2.51188643150958e.06 FALSE 574.2 Calculus of bile duct Both 303 1330 10 digestive chartreuse4 1330, 303 333, 75 332, 83 332, 64 333, 81 0.0478 0.0656 0.466 0.3312 1.05 0.922 1.19 0.107 0.178 0.547 0.2618 1.11 0.785 1.58 -0.132 0.19 0.486 0.3135 0.876 0.604 1.27 0.113 0.181 0.534 0.2723 1.12 0.785 1.6 PRS_PLINK_2.51188643150958e.06 FALSE 574.3 Cholecystitis without cholelithiasis Both 312 1294 10 digestive chartreuse4 1294, 312 324, 67 323, 89 323, 82 324, 74 0.0732 0.068 0.282 0.5498 1.08 0.942 1.23 0.371 0.183 0.0424 1.372 1.45 1.01 2.07 0.255 0.185 0.168 0.7743 1.29 0.898 1.85 0.137 0.187 0.463 0.3341 1.15 0.795 1.66 PRS_PLINK_2.51188643150958e.06 FALSE 575 Other biliary tract disease Both 814 3429 10 digestive chartreuse4 3429, 814 858, 211 857, 202 857, 205 857, 196 -0.000397 0.0386 0.992 0.003582 1 0.927 1.08 -0.0214 0.11 0.846 0.07261 0.979 0.788 1.22 -0.0214 0.11 0.846 0.07269 0.979 0.789 1.21 -0.0735 0.111 0.508 0.294 0.929 0.747 1.16 PRS_PLINK_2.51188643150958e.06 FALSE 575.1 Cholangitis Both 132 518 10 digestive chartreuse4 518, 132 130, 37 129, 30 129, 33 130, 32 0.085 0.11 0.44 0.3566 1.09 0.877 1.35 -0.131 0.287 0.649 0.1876 0.878 0.5 1.54 0.0205 0.281 0.942 0.02605 1.02 0.589 1.77 -0.0138 0.278 0.96 0.01754 0.986 0.572 1.7 PRS_PLINK_2.51188643150958e.06 FALSE 575.2 Obstruction of bile duct Both 198 901 10 digestive chartreuse4 901, 198 226, 54 225, 43 225, 43 225, 58 0.0194 0.0771 0.802 0.09592 1.02 0.877 1.19 -0.17 0.228 0.456 0.3412 0.843 0.539 1.32 -0.168 0.232 0.468 0.3296 0.845 0.536 1.33 0.0934 0.214 0.663 0.1785 1.1 0.721 1.67 PRS_PLINK_2.51188643150958e.06 FALSE 575.6 Cholesterolosis of gallbladder Both 59 281 10 digestive chartreuse4 281, 59 71, 16 70, 20 70, 12 70, 11 -0.103 0.137 0.453 0.3442 0.902 0.69 1.18 0.135 0.388 0.727 0.1385 1.14 0.535 2.45 -0.161 0.437 0.713 0.1468 0.852 0.362 2 -0.394 0.436 0.366 0.4369 0.674 0.287 1.58 PRS_PLINK_2.51188643150958e.06 FALSE 575.7 Other disorders of gallbladder Both 370 1418 10 digestive chartreuse4 1418, 370 355, 85 354, 97 354, 84 355, 104 0.0251 0.0603 0.677 0.1693 1.03 0.911 1.15 0.171 0.168 0.309 0.5107 1.19 0.853 1.65 0.011 0.172 0.949 0.02267 1.01 0.722 1.42 0.198 0.165 0.23 0.6381 1.22 0.882 1.68 PRS_PLINK_2.51188643150958e.06 FALSE 575.8 Other disorders of biliary tract Both 423 1754 10 digestive chartreuse4 1754, 423 439, 124 438, 100 438, 106 439, 93 -0.0694 0.0525 0.186 0.7305 0.933 0.842 1.03 -0.186 0.152 0.222 0.6538 0.831 0.617 1.12 -0.148 0.15 0.323 0.4905 0.862 0.642 1.16 -0.265 0.154 0.0858 1.067 0.767 0.567 1.04 PRS_PLINK_2.51188643150958e.06 FALSE 575.9 Nonspecific abnormal findings on radiological and other examination of biliary tract Both 92 376 10 digestive chartreuse4 376, 92 94, 24 94, 16 94, 28 94, 24 0.0381 0.136 0.779 0.1084 1.04 0.796 1.36 -0.261 0.373 0.484 0.3153 0.77 0.371 1.6 0.247 0.322 0.443 0.3532 1.28 0.681 2.41 -0.0522 0.329 0.874 0.05861 0.949 0.499 1.81 PRS_PLINK_2.51188643150958e.06 FALSE 577 Diseases of pancreas Both 789 3711 10 digestive chartreuse4 3711, 789 928, 188 928, 213 927, 200 928, 188 -0.0222 0.0385 0.565 0.2477 0.978 0.907 1.05 0.137 0.111 0.215 0.668 1.15 0.924 1.42 0.064 0.112 0.569 0.2452 1.07 0.855 1.33 0.0111 0.114 0.922 0.0353 1.01 0.809 1.26 PRS_PLINK_2.51188643150958e.06 FALSE 577.1 Acute pancreatitis Both 466 1996 10 digestive chartreuse4 1996, 466 499, 118 499, 109 499, 124 499, 115 -0.00363 0.0498 0.942 0.02595 0.996 0.904 1.1 -0.0468 0.148 0.752 0.1238 0.954 0.714 1.28 0.0782 0.145 0.589 0.2298 1.08 0.814 1.44 -0.00446 0.147 0.976 0.01065 0.996 0.746 1.33 PRS_PLINK_2.51188643150958e.06 FALSE 577.2 Chronic pancreatitis Both 205 880 10 digestive chartreuse4 880, 205 220, 47 220, 48 220, 56 220, 54 -0.0128 0.0705 0.855 0.0678 0.987 0.86 1.13 -0.0142 0.228 0.95 0.0222 0.986 0.631 1.54 0.162 0.227 0.474 0.3241 1.18 0.754 1.84 0.121 0.226 0.593 0.2272 1.13 0.724 1.76 PRS_PLINK_2.51188643150958e.06 FALSE 577.3 Cyst and pseudocyst of pancreas Both 206 1016 10 digestive chartreuse4 1016, 206 254, 45 254, 55 254, 56 254, 50 -0.0712 0.0701 0.31 0.509 0.931 0.812 1.07 0.19 0.22 0.389 0.4097 1.21 0.785 1.86 0.2 0.22 0.364 0.439 1.22 0.793 1.88 0.115 0.225 0.61 0.2148 1.12 0.722 1.74 PRS_PLINK_2.51188643150958e.06 FALSE 578 Gastrointestinal hemorrhage Both 1869 4275 10 digestive chartreuse4 4275, 1869 1069, 466 1069, 450 1068, 451 1069, 501 0.00999 0.028 0.721 0.1418 1.01 0.956 1.07 -0.0387 0.0795 0.627 0.2029 0.962 0.823 1.12 -0.0284 0.0794 0.721 0.1422 0.972 0.832 1.14 0.0806 0.0781 0.302 0.5199 1.08 0.93 1.26 PRS_PLINK_2.51188643150958e.06 FALSE 578.1 Hematemesis Both 215 596 10 digestive chartreuse4 596, 215 149, 63 149, 45 149, 52 149, 55 -0.0476 0.0736 0.518 0.2858 0.954 0.825 1.1 -0.29 0.23 0.206 0.6858 0.748 0.477 1.17 -0.129 0.23 0.575 0.2405 0.879 0.561 1.38 -0.0623 0.226 0.783 0.1064 0.94 0.603 1.46 PRS_PLINK_2.51188643150958e.06 FALSE 578.2 Blood in stool Both 1212 3260 10 digestive chartreuse4 3260, 1212 815, 313 815, 288 815, 292 815, 319 0.000573 0.0335 0.986 0.005968 1 0.937 1.07 -0.0793 0.0959 0.409 0.3886 0.924 0.765 1.11 -0.0707 0.0959 0.461 0.3361 0.932 0.772 1.12 0.028 0.0945 0.767 0.1153 1.03 0.855 1.24 PRS_PLINK_2.51188643150958e.06 FALSE 578.8 Hemorrhage of rectum and anus Both 896 2659 10 digestive chartreuse4 2659, 896 665, 227 665, 217 664, 197 665, 255 0.0275 0.0396 0.488 0.3118 1.03 0.951 1.11 -0.0378 0.11 0.732 0.1355 0.963 0.776 1.2 -0.147 0.113 0.192 0.7168 0.863 0.692 1.08 0.134 0.108 0.211 0.6756 1.14 0.927 1.41 PRS_PLINK_2.51188643150958e.06 FALSE 578.9 Hemorrhage of gastrointestinal tract Both 694 1954 10 digestive chartreuse4 1954, 694 489, 173 488, 156 488, 178 489, 186 0.0232 0.0447 0.605 0.2185 1.02 0.938 1.12 -0.0917 0.128 0.475 0.323 0.912 0.709 1.17 0.0475 0.125 0.704 0.1521 1.05 0.82 1.34 0.102 0.125 0.413 0.3838 1.11 0.867 1.41 PRS_PLINK_2.51188643150958e.06 FALSE 579 Other symptoms involving abdomen and pelvis Both 1604 4043 10 digestive chartreuse4 4043, 1604 1011, 382 1011, 396 1010, 422 1011, 404 0.0187 0.0305 0.541 0.2672 1.02 0.96 1.08 0.0323 0.0852 0.705 0.152 1.03 0.874 1.22 0.0944 0.0838 0.26 0.5853 1.1 0.933 1.3 0.0516 0.0848 0.543 0.2652 1.05 0.892 1.24 PRS_PLINK_2.51188643150958e.06 FALSE 579.2 Splenomegaly Both 312 871 10 digestive chartreuse4 871, 312 218, 72 218, 89 217, 70 218, 81 0.00681 0.0654 0.917 0.03757 1.01 0.886 1.14 0.194 0.189 0.304 0.5165 1.21 0.838 1.76 -0.0229 0.197 0.907 0.04219 0.977 0.664 1.44 0.117 0.192 0.541 0.2669 1.12 0.772 1.64 PRS_PLINK_2.51188643150958e.06 FALSE 579.8 Nonspecific abnormal findings in stool contents Both 640 1883 10 digestive chartreuse4 1883, 640 471, 168 471, 146 470, 166 471, 159 -0.0621 0.0471 0.188 0.7262 0.94 0.857 1.03 -0.122 0.131 0.355 0.4503 0.885 0.684 1.15 -0.0329 0.129 0.799 0.09751 0.968 0.751 1.25 -0.0599 0.13 0.644 0.1908 0.942 0.73 1.21 PRS_PLINK_2.51188643150958e.06 FALSE 580 Nephritis; nephrosis; renal sclerosis Both 776 1853 11 genitourinary black 1853, 776 464, 194 463, 176 463, 200 463, 206 0.0653 0.0461 0.157 0.8051 1.07 0.975 1.17 -0.112 0.126 0.376 0.4246 0.894 0.698 1.15 0.0485 0.122 0.692 0.1598 1.05 0.826 1.33 0.0862 0.122 0.48 0.3188 1.09 0.858 1.38 PRS_PLINK_2.51188643150958e.06 FALSE 580.1 Glomerulonephritis Both 182 479 11 genitourinary black 479, 182 120, 45 120, 38 119, 42 120, 57 0.153 0.1 0.126 0.8983 1.17 0.958 1.42 -0.133 0.262 0.612 0.2131 0.876 0.525 1.46 -0.00635 0.26 0.981 0.008537 0.994 0.597 1.66 0.274 0.242 0.258 0.5881 1.31 0.818 2.11 PRS_PLINK_2.51188643150958e.06 FALSE 580.11 Proliferative glomerulonephritis Both 57 179 11 genitourinary black 179, 57 45, 14 45, 7 44, 18 45, 18 0.126 0.166 0.446 0.3503 1.13 0.819 1.57 -0.656 0.497 0.187 0.7281 0.519 0.196 1.37 0.122 0.446 0.784 0.1055 1.13 0.471 2.71 0.184 0.425 0.665 0.1772 1.2 0.523 2.76 PRS_PLINK_2.51188643150958e.06 FALSE 580.12 Non-proliferative glomerulonephritis Both 49 126 11 genitourinary black 126, 49 32, 11 31, 8 31, 18 32, 12 0.119 0.204 0.56 0.2514 1.13 0.755 1.68 0.0893 0.59 0.88 0.05565 1.09 0.344 3.48 0.525 0.499 0.293 0.5333 1.69 0.635 4.5 0.457 0.547 0.403 0.3947 1.58 0.541 4.61 PRS_PLINK_2.51188643150958e.06 TRUE 580.13 Acute glomerulonephritis, NOS Both 28 70 11 genitourinary black 70, 28 18, 7 17, 7 17, 7 18, 7 0.0646 0.295 0.827 0.0826 1.07 0.598 1.9 0.413 0.8 0.606 0.2178 1.51 0.315 7.24 0.46 0.865 0.595 0.2256 1.58 0.291 8.63 0.218 0.701 0.756 0.1215 1.24 0.315 4.91 PRS_PLINK_2.51188643150958e.06 TRUE 580.14 Chronic glomerulonephritis, NOS Both 139 342 11 genitourinary black 342, 139 86, 43 85, 23 85, 33 86, 40 0.0466 0.11 0.672 0.1727 1.05 0.845 1.3 -0.704 0.309 0.0225 1.647 0.495 0.27 0.906 -0.236 0.29 0.416 0.3809 0.79 0.448 1.39 -0.0686 0.276 0.804 0.09489 0.934 0.544 1.6 PRS_PLINK_2.51188643150958e.06 FALSE 580.2 Nephrotic syndrome without mention of glomerulonephritis Both 83 236 11 genitourinary black 236, 83 59, 18 59, 20 59, 18 59, 27 0.214 0.15 0.153 0.8141 1.24 0.923 1.66 0.249 0.391 0.524 0.2805 1.28 0.596 2.76 0.0347 0.389 0.929 0.03203 1.04 0.483 2.22 0.503 0.372 0.177 0.7525 1.65 0.797 3.43 PRS_PLINK_2.51188643150958e.06 FALSE 580.3 Nephritis and nephropathy without mention of glomerulonephritis Both 653 1440 11 genitourinary black 1440, 653 360, 162 360, 144 360, 170 360, 177 0.0681 0.0508 0.18 0.7445 1.07 0.969 1.18 -0.156 0.14 0.266 0.5751 0.855 0.65 1.13 0.0432 0.136 0.75 0.1248 1.04 0.8 1.36 0.0928 0.134 0.489 0.3105 1.1 0.843 1.43 PRS_PLINK_2.51188643150958e.06 FALSE 580.31 Nephritis and nephropathy in diseases classified elsewhere Both 458 916 11 genitourinary black 916, 458 229, 109 229, 96 229, 125 229, 128 0.0623 0.0613 0.309 0.5098 1.06 0.944 1.2 -0.176 0.173 0.31 0.5093 0.839 0.597 1.18 0.109 0.164 0.506 0.2956 1.12 0.809 1.54 0.171 0.163 0.294 0.5318 1.19 0.862 1.63 PRS_PLINK_2.51188643150958e.06 FALSE 580.32 Nephritis and nephropathy with pathological lesion Both 287 826 11 genitourinary black 826, 287 207, 74 206, 62 206, 67 207, 84 0.0522 0.0738 0.479 0.3198 1.05 0.912 1.22 -0.192 0.201 0.34 0.4688 0.825 0.557 1.22 -0.141 0.199 0.479 0.3193 0.869 0.588 1.28 0.12 0.19 0.527 0.2781 1.13 0.777 1.64 PRS_PLINK_2.51188643150958e.06 FALSE 580.4 Renal sclerosis, NOS Both 112 405 11 genitourinary black 405, 112 102, 32 101, 24 101, 30 101, 26 -0.0562 0.105 0.591 0.2284 0.945 0.77 1.16 -0.259 0.305 0.396 0.4021 0.772 0.425 1.4 -0.061 0.293 0.835 0.07828 0.941 0.53 1.67 -0.257 0.304 0.399 0.3988 0.774 0.426 1.41 PRS_PLINK_2.51188643150958e.06 FALSE 585 Renal failure Both 2404 3768 11 genitourinary black 3768, 2404 942, 595 942, 560 942, 621 942, 627 0.0256 0.0276 0.355 0.4498 1.03 0.972 1.08 -0.0672 0.0784 0.391 0.4076 0.935 0.802 1.09 0.0446 0.0774 0.564 0.2487 1.05 0.899 1.22 0.0641 0.0778 0.41 0.3871 1.07 0.915 1.24 PRS_PLINK_2.51188643150958e.06 FALSE 585.1 Acute renal failure Both 1671 3168 11 genitourinary black 3168, 1671 792, 403 792, 377 792, 437 792, 453 0.046 0.0321 0.151 0.8207 1.05 0.983 1.12 -0.0545 0.0899 0.545 0.2638 0.947 0.794 1.13 0.101 0.0878 0.251 0.6003 1.11 0.931 1.31 0.135 0.0876 0.125 0.9043 1.14 0.963 1.36 PRS_PLINK_2.51188643150958e.06 FALSE 585.2 Renal failure NOS Both 376 1006 11 genitourinary black 1006, 376 252, 99 251, 73 251, 113 252, 90 0.0152 0.0593 0.798 0.09797 1.02 0.904 1.14 -0.284 0.179 0.113 0.9484 0.753 0.53 1.07 0.143 0.166 0.389 0.4097 1.15 0.833 1.6 -0.104 0.174 0.548 0.2608 0.901 0.641 1.27 PRS_PLINK_2.51188643150958e.06 FALSE 585.3 Chronic renal failure [CKD] Both 1814 3471 11 genitourinary black 3471, 1814 868, 449 868, 410 867, 481 868, 473 0.0197 0.0305 0.519 0.2851 1.02 0.961 1.08 -0.0992 0.0867 0.252 0.5979 0.906 0.764 1.07 0.0815 0.0849 0.337 0.472 1.08 0.919 1.28 0.0625 0.0858 0.466 0.3314 1.06 0.9 1.26 PRS_PLINK_2.51188643150958e.06 FALSE 585.31 Renal dialysis Both 298 855 11 genitourinary black 855, 298 214, 79 214, 59 213, 81 214, 79 0.04 0.0705 0.57 0.2438 1.04 0.906 1.2 -0.274 0.198 0.167 0.7764 0.76 0.515 1.12 0.0401 0.188 0.831 0.08055 1.04 0.721 1.5 0.00211 0.188 0.991 0.003907 1 0.694 1.45 PRS_PLINK_2.51188643150958e.06 FALSE 585.32 End stage renal disease Both 394 1110 11 genitourinary black 1110, 394 278, 104 277, 77 277, 105 278, 108 0.0343 0.0611 0.575 0.2403 1.03 0.918 1.17 -0.321 0.174 0.0651 1.186 0.726 0.516 1.02 0.0122 0.164 0.941 0.02658 1.01 0.734 1.4 0.0271 0.163 0.868 0.06172 1.03 0.747 1.41 PRS_PLINK_2.51188643150958e.06 FALSE 585.33 Chronic Kidney Disease, Stage III Both 1234 2510 11 genitourinary black 2510, 1234 628, 303 627, 268 627, 340 628, 322 0.0388 0.0368 0.292 0.5344 1.04 0.967 1.12 -0.117 0.103 0.26 0.5848 0.89 0.727 1.09 0.121 0.0997 0.224 0.65 1.13 0.929 1.37 0.0689 0.101 0.495 0.3054 1.07 0.879 1.31 PRS_PLINK_2.51188643150958e.06 FALSE 585.34 Chronic Kidney Disease, Stage IV Both 426 1091 11 genitourinary black 1091, 426 273, 108 273, 94 272, 125 273, 99 -0.0303 0.0594 0.61 0.2143 0.97 0.863 1.09 -0.125 0.166 0.45 0.3472 0.882 0.638 1.22 0.149 0.158 0.345 0.4627 1.16 0.852 1.58 -0.0883 0.165 0.592 0.2278 0.915 0.663 1.26 PRS_PLINK_2.51188643150958e.06 FALSE 585.4 Chronic kidney disease, Stage I or II Both 514 1365 11 genitourinary black 1365, 514 342, 128 341, 109 341, 143 341, 133 0.0514 0.0553 0.353 0.4517 1.05 0.944 1.17 -0.123 0.153 0.42 0.3772 0.884 0.655 1.19 0.136 0.145 0.348 0.4583 1.15 0.862 1.52 0.0695 0.147 0.636 0.1966 1.07 0.804 1.43 PRS_PLINK_2.51188643150958e.06 FALSE 586 Other disorders of the kidney and ureters Both 2353 3919 11 genitourinary black 3919, 2353 980, 573 980, 555 979, 605 980, 619 0.0323 0.0274 0.239 0.6219 1.03 0.979 1.09 -0.0389 0.078 0.617 0.2095 0.962 0.826 1.12 0.0714 0.0768 0.353 0.4527 1.07 0.924 1.25 0.097 0.0773 0.21 0.6786 1.1 0.947 1.28 PRS_PLINK_2.51188643150958e.06 FALSE 586.1 Anatomical abnormatilies of kidney and ureters Both 107 418 11 genitourinary black 418, 107 105, 25 104, 27 104, 36 105, 19 -0.00868 0.106 0.934 0.02944 0.991 0.806 1.22 0.0957 0.312 0.759 0.1198 1.1 0.597 2.03 0.287 0.299 0.337 0.4725 1.33 0.742 2.39 -0.28 0.333 0.402 0.3961 0.756 0.393 1.45 PRS_PLINK_2.51188643150958e.06 FALSE 586.11 Small kidney Both 64 262 11 genitourinary black 262, 64 66, 21 65, 14 65, 15 66, 14 -0.107 0.131 0.413 0.3839 0.898 0.694 1.16 -0.344 0.384 0.372 0.4299 0.709 0.334 1.51 -0.33 0.378 0.383 0.4172 0.719 0.343 1.51 -0.455 0.388 0.241 0.6176 0.635 0.297 1.36 PRS_PLINK_2.51188643150958e.06 FALSE 586.12 Vesicoureteral reflux Both 39 142 11 genitourinary black 142, 39 36, 4 35, 12 35, 15 36, 8 0.112 0.208 0.591 0.2284 1.12 0.743 1.68 0.986 0.572 0.0846 1.072 2.68 0.874 8.22 1.01 0.621 0.103 0.9871 2.75 0.815 9.3 0.573 0.666 0.39 0.4092 1.77 0.481 6.55 PRS_PLINK_2.51188643150958e.06 TRUE 586.2 Cyst of kidney, acquired Both 463 1555 11 genitourinary black 1555, 463 389, 110 389, 94 388, 133 389, 126 0.0652 0.0547 0.233 0.6327 1.07 0.959 1.19 -0.126 0.16 0.431 0.3659 0.882 0.645 1.21 0.216 0.149 0.147 0.8319 1.24 0.927 1.66 0.126 0.151 0.406 0.3915 1.13 0.843 1.53 PRS_PLINK_2.51188643150958e.06 FALSE 586.3 Vascular disorders of kidney/hypertrophy Both 59 229 11 genitourinary black 229, 59 58, 14 57, 12 57, 18 57, 15 0.0913 0.163 0.575 0.2403 1.1 0.796 1.51 -0.138 0.437 0.753 0.1234 0.871 0.37 2.05 0.381 0.432 0.377 0.4236 1.46 0.628 3.41 0.0301 0.42 0.943 0.02554 1.03 0.452 2.35 PRS_PLINK_2.51188643150958e.06 FALSE 586.4 Stricture/obstruction of ureter Both 473 1988 11 genitourinary black 1988, 473 497, 109 497, 100 497, 125 497, 139 0.112 0.0548 0.0405 1.393 1.12 1 1.25 -0.0671 0.153 0.661 0.1799 0.935 0.693 1.26 0.156 0.147 0.287 0.5426 1.17 0.877 1.56 0.252 0.146 0.0839 1.076 1.29 0.967 1.71 PRS_PLINK_2.51188643150958e.06 FALSE 587 Kidney replaced by transpant Both 287 895 11 genitourinary black 895, 287 224, 61 224, 67 223, 84 224, 75 0.0556 0.0722 0.442 0.355 1.06 0.918 1.22 0.0731 0.203 0.719 0.1435 1.08 0.723 1.6 0.345 0.197 0.0802 1.096 1.41 0.959 2.08 0.217 0.199 0.275 0.56 1.24 0.841 1.83 PRS_PLINK_2.51188643150958e.06 FALSE 588 Disorders resulting from impaired renal function Both 438 1131 11 genitourinary black 1131, 438 283, 104 283, 94 282, 129 283, 111 0.0709 0.0585 0.225 0.6479 1.07 0.957 1.2 -0.103 0.167 0.535 0.2719 0.902 0.651 1.25 0.233 0.158 0.141 0.8509 1.26 0.926 1.72 0.0762 0.162 0.638 0.1949 1.08 0.785 1.48 PRS_PLINK_2.51188643150958e.06 FALSE 588.1 Renal osteodystrophy Both 110 316 11 genitourinary black 316, 110 79, 24 79, 26 79, 37 79, 23 0.0622 0.108 0.564 0.2484 1.06 0.861 1.31 0.0365 0.329 0.912 0.0401 1.04 0.544 1.98 0.428 0.316 0.176 0.7555 1.53 0.826 2.85 -0.0477 0.337 0.888 0.05177 0.953 0.492 1.85 PRS_PLINK_2.51188643150958e.06 FALSE 588.2 Secondary hyperparathyroidism (of renal origin) Both 339 896 11 genitourinary black 896, 339 224, 88 224, 69 224, 93 224, 89 0.0581 0.0667 0.384 0.4157 1.06 0.93 1.21 -0.228 0.188 0.224 0.6493 0.796 0.551 1.15 0.0699 0.178 0.695 0.1578 1.07 0.756 1.52 0.0279 0.181 0.877 0.05681 1.03 0.721 1.47 PRS_PLINK_2.51188643150958e.06 FALSE 589 Abnormal results of function study of kidney Both 455 1234 11 genitourinary black 1234, 455 309, 110 308, 102 308, 122 309, 121 0.0544 0.0587 0.354 0.451 1.06 0.941 1.18 -0.0555 0.161 0.73 0.1369 0.946 0.69 1.3 0.111 0.155 0.474 0.3239 1.12 0.824 1.52 0.0941 0.156 0.546 0.2627 1.1 0.809 1.49 PRS_PLINK_2.51188643150958e.06 FALSE 590 Pyelonephritis Both 558 1659 11 genitourinary black 1659, 558 415, 115 415, 137 414, 147 415, 159 0.119 0.0524 0.0237 1.625 1.13 1.02 1.25 0.158 0.145 0.277 0.5577 1.17 0.881 1.56 0.231 0.143 0.108 0.9666 1.26 0.951 1.67 0.313 0.142 0.0273 1.564 1.37 1.04 1.81 PRS_PLINK_2.51188643150958e.06 FALSE 591 Urinary tract infection Both 3107 3641 11 genitourinary black 3641, 3107 910, 745 910, 782 910, 778 910, 802 0.0389 0.0255 0.127 0.8976 1.04 0.989 1.09 0.00838 0.0728 0.908 0.04178 1.01 0.874 1.16 0.0271 0.0724 0.708 0.1501 1.03 0.892 1.18 0.0795 0.0721 0.271 0.5677 1.08 0.94 1.25 PRS_PLINK_2.51188643150958e.06 FALSE 592 Cystitis and urethritis Both 1120 2805 11 genitourinary black 2805, 1120 701, 261 701, 272 701, 298 701, 289 0.0787 0.0374 0.0352 1.454 1.08 1.01 1.16 0.0154 0.104 0.882 0.05433 1.02 0.828 1.25 0.134 0.102 0.189 0.7234 1.14 0.936 1.4 0.0902 0.103 0.38 0.4201 1.09 0.895 1.34 PRS_PLINK_2.51188643150958e.06 FALSE 592.1 Cystitis Both 1076 2715 11 genitourinary black 2715, 1076 678, 247 679, 268 678, 282 679, 279 0.0845 0.0384 0.0278 1.556 1.09 1.01 1.17 0.0577 0.106 0.586 0.2319 1.06 0.861 1.3 0.13 0.105 0.213 0.6725 1.14 0.928 1.4 0.109 0.105 0.301 0.5213 1.11 0.907 1.37 PRS_PLINK_2.51188643150958e.06 FALSE 592.11 Acute cystitis Both 735 1921 11 genitourinary black 1921, 735 480, 165 480, 190 480, 202 480, 178 0.0697 0.0468 0.136 0.8653 1.07 0.978 1.18 0.123 0.126 0.33 0.482 1.13 0.883 1.45 0.22 0.125 0.0776 1.11 1.25 0.976 1.59 0.0695 0.128 0.587 0.2316 1.07 0.835 1.38 PRS_PLINK_2.51188643150958e.06 FALSE 592.12 Chronic cystitis Both 97 294 11 genitourinary black 294, 97 74, 28 73, 22 73, 30 74, 17 0.00325 0.136 0.981 0.008373 1 0.769 1.31 -0.256 0.339 0.45 0.3464 0.774 0.398 1.5 0.0844 0.321 0.792 0.1011 1.09 0.58 2.04 -0.457 0.352 0.195 0.7108 0.633 0.318 1.26 PRS_PLINK_2.51188643150958e.06 FALSE 592.13 Chronic interstitial cystitis Both 124 492 11 genitourinary black 492, 124 122, 33 123, 31 123, 26 123, 34 0.0435 0.0997 0.662 0.1789 1.04 0.859 1.27 0.0436 0.285 0.878 0.05628 1.04 0.597 1.83 -0.209 0.292 0.475 0.323 0.812 0.458 1.44 0.103 0.281 0.713 0.1468 1.11 0.639 1.93 PRS_PLINK_2.51188643150958e.06 FALSE 592.2 Urethritis and urethral syndrome Both 67 234 11 genitourinary black 234, 67 59, 17 58, 8 58, 23 59, 19 0.0151 0.145 0.917 0.03762 1.02 0.764 1.35 -0.815 0.481 0.0903 1.044 0.442 0.172 1.14 0.3 0.389 0.441 0.3558 1.35 0.63 2.89 0.106 0.382 0.781 0.1074 1.11 0.526 2.35 PRS_PLINK_2.51188643150958e.06 FALSE 593 Hematuria Both 1656 3598 11 genitourinary black 3598, 1656 899, 382 899, 426 899, 433 900, 415 0.0506 0.0307 0.0991 1.004 1.05 0.991 1.12 0.105 0.0869 0.228 0.6418 1.11 0.937 1.32 0.14 0.0864 0.106 0.9758 1.15 0.971 1.36 0.0974 0.0873 0.265 0.5775 1.1 0.929 1.31 PRS_PLINK_2.51188643150958e.06 FALSE 593.1 Gross hematuria Both 514 1795 11 genitourinary black 1795, 514 448, 107 449, 131 448, 123 449, 153 0.12 0.052 0.021 1.678 1.13 1.02 1.25 0.211 0.148 0.152 0.818 1.24 0.925 1.65 0.13 0.149 0.381 0.4187 1.14 0.851 1.53 0.381 0.144 0.00824 2.084 1.46 1.1 1.94 PRS_PLINK_2.51188643150958e.06 FALSE 593.2 Microscopic hematuria Both 390 1237 11 genitourinary black 1237, 390 310, 95 309, 94 309, 107 309, 94 0.0355 0.0576 0.538 0.2695 1.04 0.925 1.16 -0.0112 0.167 0.947 0.02377 0.989 0.712 1.37 0.126 0.164 0.439 0.3574 1.13 0.824 1.56 -0.0289 0.168 0.864 0.06365 0.972 0.698 1.35 PRS_PLINK_2.51188643150958e.06 FALSE 594 Urinary calculus Both 1598 5562 11 genitourinary black 5562, 1598 1390, 391 1390, 399 1390, 387 1391, 421 0.0382 0.029 0.187 0.7272 1.04 0.982 1.1 0.0231 0.0809 0.775 0.1105 1.02 0.873 1.2 -0.00552 0.0815 0.946 0.02411 0.994 0.848 1.17 0.0648 0.0805 0.421 0.3757 1.07 0.911 1.25 PRS_PLINK_2.51188643150958e.06 FALSE 594.1 Calculus of kidney Both 1509 5546 11 genitourinary black 5546, 1509 1386, 370 1386, 368 1386, 371 1387, 400 0.0371 0.0296 0.21 0.6779 1.04 0.979 1.1 -0.00417 0.0831 0.96 0.01773 0.996 0.846 1.17 0.00385 0.0831 0.963 0.01637 1 0.853 1.18 0.0671 0.0822 0.414 0.3827 1.07 0.91 1.26 PRS_PLINK_2.51188643150958e.06 FALSE 594.2 Calculus of lower urinary tract Both 96 565 11 genitourinary black 565, 96 142, 16 141, 22 141, 26 141, 32 0.41 0.137 0.00275 2.56 1.51 1.15 1.97 0.305 0.343 0.373 0.4279 1.36 0.693 2.66 0.518 0.336 0.123 0.9096 1.68 0.869 3.24 0.641 0.325 0.0488 1.312 1.9 1 3.59 PRS_PLINK_2.51188643150958e.06 FALSE 594.3 Calculus of ureter Both 419 1975 11 genitourinary black 1975, 419 494, 98 494, 108 493, 102 494, 111 0.0637 0.0556 0.252 0.5986 1.07 0.956 1.19 0.107 0.154 0.485 0.3138 1.11 0.823 1.51 0.0694 0.155 0.655 0.1837 1.07 0.79 1.45 0.139 0.153 0.364 0.4392 1.15 0.852 1.55 PRS_PLINK_2.51188643150958e.06 FALSE 594.8 Renal colic Both 125 485 11 genitourinary black 485, 125 122, 28 121, 40 121, 29 121, 28 -0.0178 0.0963 0.853 0.06897 0.982 0.813 1.19 0.333 0.279 0.232 0.6336 1.4 0.808 2.41 0.0439 0.299 0.884 0.05378 1.04 0.581 1.88 0.0565 0.302 0.852 0.06974 1.06 0.585 1.91 PRS_PLINK_2.51188643150958e.06 FALSE 595 Hydronephrosis Both 488 2403 11 genitourinary black 2403, 488 600, 115 601, 125 600, 118 601, 130 0.0867 0.052 0.0954 1.021 1.09 0.985 1.21 0.0764 0.141 0.589 0.2301 1.08 0.818 1.42 0.035 0.144 0.807 0.0929 1.04 0.781 1.37 0.115 0.141 0.417 0.3796 1.12 0.85 1.48 PRS_PLINK_2.51188643150958e.06 FALSE 596 Other disorders of bladder Both 959 4347 11 genitourinary black 4347, 959 1086, 240 1087, 243 1086, 239 1087, 237 0.00105 0.0356 0.976 0.01039 1 0.934 1.07 0.0353 0.101 0.727 0.1385 1.04 0.85 1.26 -0.000322 0.101 0.997 0.001104 1 0.82 1.22 0.00211 0.102 0.983 0.007235 1 0.821 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 596.1 Bladder neck obstruction Both 92 584 11 genitourinary black 584, 92 146, 13 146, 30 146, 26 146, 23 0.0981 0.119 0.411 0.386 1.1 0.873 1.39 0.833 0.346 0.0161 1.792 2.3 1.17 4.53 0.654 0.351 0.0627 1.203 1.92 0.966 3.83 0.489 0.361 0.176 0.7555 1.63 0.803 3.31 PRS_PLINK_2.51188643150958e.06 FALSE 596.5 Functional disorders of bladder Both 592 2712 11 genitourinary black 2712, 592 678, 158 678, 152 678, 136 678, 146 -0.0225 0.0456 0.621 0.207 0.978 0.894 1.07 -0.0233 0.127 0.854 0.06852 0.977 0.762 1.25 -0.155 0.129 0.23 0.6385 0.856 0.665 1.1 -0.0772 0.128 0.546 0.2629 0.926 0.721 1.19 PRS_PLINK_2.51188643150958e.06 FALSE 597 Other disorders of urethra and urinary tract Both 280 1689 11 genitourinary black 1689, 280 423, 64 422, 78 422, 58 422, 80 0.0384 0.0673 0.569 0.2452 1.04 0.911 1.19 0.209 0.182 0.25 0.6015 1.23 0.863 1.76 -0.0789 0.194 0.685 0.1645 0.924 0.631 1.35 0.214 0.181 0.237 0.6246 1.24 0.868 1.77 PRS_PLINK_2.51188643150958e.06 FALSE 597.1 Urethral stricture (not specified as infectious) Both 126 858 11 genitourinary black 858, 126 215, 26 214, 39 214, 27 215, 34 0.115 0.0971 0.237 0.6246 1.12 0.927 1.36 0.407 0.268 0.128 0.8913 1.5 0.889 2.54 0.0833 0.293 0.776 0.1102 1.09 0.612 1.93 0.233 0.276 0.399 0.3987 1.26 0.735 2.17 PRS_PLINK_2.51188643150958e.06 FALSE 597.2 Urinary complications NEC Both 291 1558 11 genitourinary black 1558, 291 389, 81 389, 60 389, 62 390, 88 0.057 0.0668 0.394 0.405 1.06 0.929 1.21 -0.33 0.185 0.0738 1.132 0.719 0.501 1.03 -0.266 0.184 0.147 0.8335 0.766 0.535 1.1 0.0983 0.17 0.564 0.2489 1.1 0.79 1.54 PRS_PLINK_2.51188643150958e.06 FALSE 597.8 Urethral hypermobility/ISD Both 42 315 11 genitourinary black 315, 42 79, 7 79, 12 78, 7 79, 16 0.337 0.195 0.0839 1.076 1.4 0.956 2.05 0.407 0.475 0.392 0.407 1.5 0.592 3.82 0.0167 0.52 0.974 0.01126 1.02 0.367 2.82 0.715 0.458 0.119 0.9254 2.04 0.833 5.02 PRS_PLINK_2.51188643150958e.06 TRUE 598 Abnormal findings on examination of urine Both 62 245 11 genitourinary black 245, 62 62, 12 61, 12 61, 20 61, 18 0.155 0.156 0.321 0.4935 1.17 0.86 1.58 0.104 0.452 0.818 0.08742 1.11 0.458 2.69 0.68 0.443 0.124 0.9053 1.97 0.829 4.7 0.417 0.454 0.358 0.4467 1.52 0.624 3.69 PRS_PLINK_2.51188643150958e.06 FALSE 598.4 Other cells and casts in urine Both 52 222 11 genitourinary black 222, 52 56, 11 55, 9 55, 17 56, 15 0.138 0.16 0.386 0.4137 1.15 0.84 1.57 0.00213 0.496 0.997 0.00149 1 0.379 2.65 0.549 0.456 0.229 0.6404 1.73 0.708 4.23 0.364 0.482 0.45 0.3472 1.44 0.56 3.7 PRS_PLINK_2.51188643150958e.06 FALSE 599 Other symptoms/disorders or the urinary system Both 3935 3187 11 genitourinary black 3187, 3935 796, 925 797, 1017 796, 1035 797, 958 0.0329 0.0245 0.179 0.7461 1.03 0.985 1.08 0.0707 0.0703 0.315 0.5022 1.07 0.935 1.23 0.115 0.0698 0.0986 1.006 1.12 0.979 1.29 0.0477 0.0705 0.499 0.302 1.05 0.913 1.2 PRS_PLINK_2.51188643150958e.06 FALSE 599.1 Urinary obstruction Both 235 726 11 genitourinary black 726, 235 181, 55 181, 60 181, 58 182, 62 0.052 0.0794 0.512 0.2903 1.05 0.902 1.23 0.157 0.221 0.48 0.3192 1.17 0.758 1.8 0.0198 0.218 0.927 0.03273 1.02 0.666 1.56 0.15 0.22 0.497 0.3039 1.16 0.755 1.79 PRS_PLINK_2.51188643150958e.06 FALSE 599.2 Retention of urine Both 1448 2980 11 genitourinary black 2980, 1448 744, 361 745, 361 745, 367 745, 359 0.0296 0.0329 0.369 0.4332 1.03 0.966 1.1 -0.00738 0.0944 0.938 0.02795 0.993 0.825 1.19 0.0377 0.0938 0.687 0.1628 1.04 0.864 1.25 0.00241 0.0945 0.98 0.008936 1 0.833 1.21 PRS_PLINK_2.51188643150958e.06 FALSE 599.3 Dysuria Both 1529 2998 11 genitourinary black 2998, 1529 749, 362 749, 397 749, 382 750, 388 0.0303 0.032 0.343 0.465 1.03 0.968 1.1 0.0646 0.0919 0.482 0.3169 1.07 0.891 1.28 0.042 0.092 0.648 0.1885 1.04 0.871 1.25 0.06 0.0916 0.512 0.2906 1.06 0.887 1.27 PRS_PLINK_2.51188643150958e.06 FALSE 599.4 Urinary incontinence Both 1709 2942 11 genitourinary black 2942, 1709 735, 415 735, 436 735, 453 736, 405 -0.00412 0.0308 0.894 0.04876 0.996 0.937 1.06 0.00202 0.0911 0.982 0.007732 1 0.838 1.2 0.0603 0.0896 0.501 0.2999 1.06 0.891 1.27 -0.0408 0.0914 0.655 0.1836 0.96 0.802 1.15 PRS_PLINK_2.51188643150958e.06 FALSE 599.5 Frequency of urination and polyuria Both 1769 3089 11 genitourinary black 3089, 1769 772, 427 772, 468 772, 435 772, 439 0.0413 0.0307 0.179 0.7465 1.04 0.981 1.11 0.0646 0.0877 0.461 0.3362 1.07 0.898 1.27 0.0139 0.088 0.875 0.05812 1.01 0.853 1.2 0.0377 0.088 0.669 0.1747 1.04 0.874 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 599.6 Oliguria and anuria Both 217 621 11 genitourinary black 621, 217 156, 60 155, 52 155, 54 155, 51 -0.149 0.0729 0.0408 1.39 0.861 0.747 0.994 -0.163 0.225 0.469 0.3286 0.85 0.547 1.32 -0.108 0.222 0.625 0.2041 0.897 0.581 1.39 -0.15 0.225 0.505 0.2964 0.861 0.554 1.34 PRS_PLINK_2.51188643150958e.06 FALSE 599.7 Urethral discharge Both 30 133 11 genitourinary black 133, 30 34, 5 33, 9 33, 7 33, 9 0.0867 0.226 0.701 0.1541 1.09 0.7 1.7 0.397 0.592 0.502 0.2992 1.49 0.466 4.75 0.353 0.626 0.573 0.2422 1.42 0.417 4.86 0.112 0.633 0.86 0.06555 1.12 0.324 3.86 PRS_PLINK_2.51188643150958e.06 TRUE 599.8 Other symptoms involving urinary system Both 1634 3040 11 genitourinary black 3040, 1634 759, 372 760, 423 760, 425 760, 414 0.0463 0.0319 0.146 0.8345 1.05 0.984 1.11 0.113 0.0918 0.219 0.6605 1.12 0.935 1.34 0.131 0.0914 0.15 0.8229 1.14 0.953 1.36 0.087 0.0924 0.346 0.4609 1.09 0.91 1.31 PRS_PLINK_2.51188643150958e.06 FALSE 599.9 Other abnormality of urination Both 1056 2775 11 genitourinary black 2775, 1056 693, 262 694, 275 693, 259 694, 260 0.00461 0.0359 0.898 0.04678 1 0.936 1.08 0.0362 0.104 0.727 0.1382 1.04 0.846 1.27 -0.00785 0.105 0.94 0.02672 0.992 0.808 1.22 -0.0142 0.105 0.892 0.04958 0.986 0.803 1.21 PRS_PLINK_2.51188643150958e.06 FALSE 600 Hyperplasia of prostate Male 1085 1397 11 genitourinary black 1397, 1085 349, 285 349, 254 349, 273 349, 273 -0.00959 0.0438 0.827 0.08262 0.99 0.909 1.08 -0.0935 0.129 0.468 0.3296 0.911 0.707 1.17 -0.0677 0.127 0.594 0.2263 0.935 0.729 1.2 -0.0125 0.127 0.922 0.03549 0.988 0.77 1.27 PRS_PLINK_2.51188643150958e.06 FALSE 601 Inflammatory diseases of prostate Male 310 1152 11 genitourinary black 1152, 310 287, 84 288, 66 288, 72 288, 88 0.0375 0.0665 0.573 0.242 1.04 0.911 1.18 -0.2 0.188 0.287 0.5424 0.818 0.566 1.18 -0.136 0.184 0.461 0.3358 0.873 0.609 1.25 0.0689 0.18 0.701 0.1543 1.07 0.754 1.52 PRS_PLINK_2.51188643150958e.06 FALSE 601.1 Prostatitis Male 153 588 11 genitourinary black 588, 153 146, 46 147, 37 147, 34 147, 36 -0.0843 0.0835 0.313 0.5048 0.919 0.78 1.08 -0.271 0.254 0.287 0.5426 0.763 0.463 1.26 -0.35 0.26 0.178 0.749 0.705 0.424 1.17 -0.291 0.261 0.265 0.5773 0.747 0.448 1.25 PRS_PLINK_2.51188643150958e.06 FALSE 601.11 Acute prostatitis Male 37 143 11 genitourinary black 143, 37 35, 12 36, 10 35, 7 36, 8 -0.0522 0.173 0.762 0.1178 0.949 0.677 1.33 -0.185 0.519 0.721 0.142 0.831 0.3 2.3 -0.701 0.574 0.222 0.653 0.496 0.161 1.53 -0.257 0.548 0.639 0.1944 0.773 0.264 2.27 PRS_PLINK_2.51188643150958e.06 TRUE 601.12 Chronic prostatitis Male 27 135 11 genitourinary black 135, 27 34, 9 34, 6 33, 5 34, 7 -0.401 0.173 0.0203 1.693 0.67 0.478 0.94 -0.771 0.642 0.23 0.6387 0.462 0.131 1.63 -0.452 0.616 0.463 0.3341 0.637 0.19 2.13 -0.521 0.605 0.389 0.4098 0.594 0.182 1.94 PRS_PLINK_2.51188643150958e.06 TRUE 601.3 Orchitis and epididymitis Male 115 467 11 genitourinary black 467, 115 117, 34 117, 24 116, 25 117, 32 -0.0566 0.0986 0.566 0.2471 0.945 0.779 1.15 -0.313 0.302 0.3 0.5227 0.731 0.404 1.32 -0.231 0.3 0.442 0.3544 0.794 0.441 1.43 0.0139 0.29 0.962 0.01689 1.01 0.574 1.79 PRS_PLINK_2.51188643150958e.06 FALSE 601.4 Balanoposthitis Male 33 124 11 genitourinary black 124, 33 30, 15 31, 4 31, 7 31, 7 -0.0328 0.172 0.848 0.07137 0.968 0.691 1.35 -0.945 0.622 0.129 0.8897 0.389 0.115 1.32 -0.557 0.564 0.324 0.49 0.573 0.19 1.73 -0.756 0.556 0.174 0.7594 0.47 0.158 1.4 PRS_PLINK_2.51188643150958e.06 TRUE 601.8 Other inflammatory disorders of male genital organs Male 51 194 11 genitourinary black 194, 51 49, 8 48, 7 48, 17 49, 19 0.508 0.208 0.0146 1.837 1.66 1.11 2.5 -0.341 0.575 0.554 0.2566 0.711 0.23 2.2 0.869 0.493 0.0781 1.107 2.39 0.907 6.28 0.914 0.475 0.0541 1.267 2.49 0.984 6.33 PRS_PLINK_2.51188643150958e.06 FALSE 602 Other disorders of prostate Male 104 421 11 genitourinary black 421, 104 106, 24 105, 29 105, 26 105, 25 -0.0598 0.103 0.562 0.2502 0.942 0.77 1.15 0.19 0.318 0.551 0.259 1.21 0.648 2.26 0.00383 0.321 0.99 0.004152 1 0.535 1.88 0.0667 0.328 0.839 0.07624 1.07 0.562 2.03 PRS_PLINK_2.51188643150958e.06 FALSE 602.3 Dysplasia of prostate Male 23 96 11 genitourinary black 96, 23 24, 3 24, 5 24, 5 24, 10 0.0647 0.208 0.756 0.1216 1.07 0.71 1.6 0.277 0.745 0.71 0.1489 1.32 0.306 5.69 0.531 0.797 0.506 0.2962 1.7 0.356 8.11 1.22 0.768 0.113 0.9451 3.37 0.749 15.2 PRS_PLINK_2.51188643150958e.06 TRUE 603 Other disorders of testis Male 121 445 11 genitourinary black 445, 121 112, 28 111, 31 111, 23 111, 39 0.128 0.102 0.209 0.6792 1.14 0.931 1.39 0.198 0.301 0.509 0.2932 1.22 0.677 2.2 -0.148 0.313 0.638 0.1954 0.863 0.467 1.59 0.374 0.292 0.199 0.7011 1.45 0.821 2.58 PRS_PLINK_2.51188643150958e.06 FALSE 603.1 Hydrocele Male 84 323 11 genitourinary black 323, 84 81, 17 81, 22 80, 14 81, 31 0.226 0.127 0.0746 1.127 1.25 0.978 1.61 0.357 0.375 0.342 0.4666 1.43 0.685 2.98 -0.0613 0.402 0.879 0.05608 0.941 0.428 2.07 0.627 0.355 0.077 1.114 1.87 0.934 3.75 PRS_PLINK_2.51188643150958e.06 FALSE 603.2 Spermatocele Male 41 148 11 genitourinary black 148, 41 37, 8 37, 10 37, 9 37, 14 0.287 0.197 0.144 0.8429 1.33 0.907 1.96 0.575 0.583 0.324 0.4899 1.78 0.567 5.57 0.156 0.573 0.785 0.1052 1.17 0.38 3.59 1.29 0.612 0.0346 1.461 3.64 1.1 12.1 PRS_PLINK_2.51188643150958e.06 TRUE 604 Disorders of penis Male 173 687 11 genitourinary black 687, 173 171, 49 172, 47 171, 43 172, 34 -0.0478 0.0833 0.566 0.2469 0.953 0.81 1.12 -0.0475 0.233 0.838 0.07654 0.954 0.604 1.51 -0.0911 0.241 0.705 0.1519 0.913 0.57 1.46 -0.312 0.249 0.21 0.6784 0.732 0.449 1.19 PRS_PLINK_2.51188643150958e.06 FALSE 604.1 Redundant prepuce and phimosis/BXO Male 37 157 11 genitourinary black 157, 37 40, 13 39, 8 39, 9 39, 7 -0.058 0.205 0.777 0.1094 0.944 0.631 1.41 -0.685 0.529 0.196 0.7086 0.504 0.179 1.42 -0.244 0.522 0.64 0.1937 0.784 0.282 2.18 -0.81 0.561 0.149 0.8271 0.445 0.148 1.34 PRS_PLINK_2.51188643150958e.06 TRUE 604.3 Peyronie's disease Male 34 236 11 genitourinary black 236, 34 59, 3 59, 13 59, 13 59, 5 0.174 0.232 0.454 0.3434 1.19 0.755 1.87 1.33 0.628 0.0346 1.461 3.77 1.1 12.9 1.31 0.608 0.0308 1.512 3.72 1.13 12.2 0.272 0.689 0.693 0.1591 1.31 0.34 5.06 PRS_PLINK_2.51188643150958e.06 TRUE 605 Erectile dysfunction [ED] Male 917 1265 11 genitourinary black 1265, 917 316, 232 316, 222 316, 230 316, 233 0.0386 0.0456 0.397 0.4008 1.04 0.951 1.14 -0.0405 0.129 0.753 0.1229 0.96 0.746 1.24 0.0237 0.129 0.854 0.06863 1.02 0.795 1.32 0.0191 0.127 0.881 0.05507 1.02 0.794 1.31 PRS_PLINK_2.51188643150958e.06 FALSE 608 Other disorders of male genital organs Male 434 1294 11 genitourinary black 1294, 434 323, 109 323, 115 323, 100 324, 110 -0.0153 0.0545 0.779 0.1086 0.985 0.885 1.1 0.0978 0.158 0.536 0.2707 1.1 0.809 1.5 -0.0574 0.162 0.723 0.1407 0.944 0.687 1.3 0.0493 0.159 0.757 0.121 1.05 0.769 1.44 PRS_PLINK_2.51188643150958e.06 FALSE 609 Male infertility and abnormal spermatozoa Male 84 413 11 genitourinary black 413, 84 104, 19 103, 27 103, 25 103, 13 -0.122 0.111 0.273 0.5635 0.885 0.712 1.1 0.455 0.334 0.173 0.7622 1.58 0.819 3.03 0.308 0.339 0.364 0.4388 1.36 0.7 2.64 -0.343 0.38 0.366 0.436 0.71 0.337 1.49 PRS_PLINK_2.51188643150958e.06 FALSE 609.1 Infertility, male Male 53 276 11 genitourinary black 276, 53 69, 12 69, 19 69, 13 69, 9 -0.169 0.146 0.249 0.603 0.845 0.634 1.13 0.438 0.401 0.275 0.5608 1.55 0.706 3.4 0.138 0.431 0.749 0.1254 1.15 0.493 2.67 -0.316 0.484 0.514 0.2893 0.729 0.282 1.88 PRS_PLINK_2.51188643150958e.06 FALSE 609.11 Azoospermia and oligospermia Male 15 78 11 genitourinary black 78, 15 20, 4 19, 5 19, 4 20, 2 -0.379 0.302 0.209 0.6806 0.684 0.379 1.24 0.404 0.971 0.678 0.169 1.5 0.223 10.1 -0.32 0.839 0.702 0.1534 0.726 0.14 3.76 -0.867 0.973 0.373 0.4285 0.42 0.0624 2.83 PRS_PLINK_2.51188643150958e.06 TRUE 609.2 Abnormal spermatozoa Male 33 165 11 genitourinary black 165, 33 42, 8 41, 12 41, 8 41, 5 -0.208 0.18 0.247 0.6071 0.812 0.571 1.15 0.355 0.515 0.491 0.3093 1.43 0.52 3.92 -0.00514 0.578 0.993 0.003093 0.995 0.32 3.09 -0.454 0.593 0.444 0.3522 0.635 0.199 2.03 PRS_PLINK_2.51188643150958e.06 TRUE 610 Benign mammary dysplasias Female 978 2058 11 genitourinary black 2058, 978 515, 250 514, 267 514, 242 515, 219 -0.0288 0.0401 0.473 0.3256 0.972 0.898 1.05 0.0429 0.111 0.699 0.1553 1.04 0.84 1.3 -0.0614 0.113 0.587 0.2316 0.94 0.754 1.17 -0.125 0.116 0.279 0.5543 0.882 0.703 1.11 PRS_PLINK_2.51188643150958e.06 FALSE 610.1 Cystic mastopathy Female 443 1799 11 genitourinary black 1799, 443 450, 111 450, 131 449, 111 450, 90 -0.0715 0.0515 0.165 0.7821 0.931 0.842 1.03 0.154 0.147 0.293 0.5336 1.17 0.875 1.56 -0.0254 0.152 0.867 0.06179 0.975 0.723 1.31 -0.206 0.159 0.195 0.7098 0.813 0.595 1.11 PRS_PLINK_2.51188643150958e.06 FALSE 610.2 Fibroadenosis of breast Female 22 82 11 genitourinary black 82, 22 21, 7 20, 7 20, 2 21, 6 -0.00736 0.206 0.971 0.01257 0.993 0.663 1.49 0.336 0.696 0.629 0.2014 1.4 0.358 5.48 -1.57 1.04 0.132 0.8796 0.208 0.0269 1.6 -0.167 0.672 0.804 0.09485 0.846 0.227 3.16 PRS_PLINK_2.51188643150958e.06 TRUE 610.4 Benign neoplasm of breast Female 744 2045 11 genitourinary black 2045, 744 512, 183 511, 198 511, 189 511, 174 0.0124 0.045 0.782 0.1067 1.01 0.927 1.11 0.0302 0.124 0.808 0.09285 1.03 0.809 1.31 -0.00503 0.125 0.968 0.01423 0.995 0.78 1.27 -0.0425 0.127 0.738 0.1319 0.958 0.747 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 610.8 Other specified benign mammary dysplasias Female 320 1523 11 genitourinary black 1523, 320 381, 84 381, 90 380, 79 381, 67 -0.053 0.0596 0.374 0.4269 0.948 0.844 1.07 0.0776 0.169 0.647 0.1894 1.08 0.776 1.51 -0.0476 0.174 0.784 0.1054 0.953 0.678 1.34 -0.202 0.181 0.264 0.5782 0.817 0.573 1.17 PRS_PLINK_2.51188643150958e.06 FALSE 611 Abnormal findings on mammogram or breast exam Both 1872 2387 11 genitourinary black 2387, 1872 597, 460 597, 507 596, 451 597, 454 -0.0125 0.0321 0.697 0.157 0.988 0.927 1.05 0.0605 0.0902 0.502 0.2991 1.06 0.89 1.27 -0.0492 0.0917 0.592 0.2279 0.952 0.795 1.14 0.0176 0.0923 0.849 0.07122 1.02 0.849 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 611.1 Abnormal mammogram Both 1532 2053 11 genitourinary black 2053, 1532 514, 366 513, 413 513, 375 513, 378 0.00454 0.0354 0.898 0.0467 1 0.937 1.08 0.0832 0.0987 0.399 0.3988 1.09 0.896 1.32 -0.011 0.1 0.912 0.03985 0.989 0.813 1.2 0.062 0.1 0.536 0.2706 1.06 0.874 1.3 PRS_PLINK_2.51188643150958e.06 FALSE 611.11 Mammographic microcalcification Both 360 1335 11 genitourinary black 1335, 360 334, 89 334, 98 333, 77 334, 96 0.0355 0.0618 0.565 0.2477 1.04 0.918 1.17 0.0936 0.169 0.579 0.237 1.1 0.789 1.53 -0.138 0.177 0.436 0.3601 0.871 0.615 1.23 0.124 0.169 0.462 0.3352 1.13 0.813 1.58 PRS_PLINK_2.51188643150958e.06 FALSE 611.3 Lump or mass in breast Both 1114 2358 11 genitourinary black 2358, 1114 590, 285 589, 307 589, 261 590, 261 -0.0307 0.0365 0.4 0.3976 0.97 0.903 1.04 0.045 0.103 0.664 0.178 1.05 0.854 1.28 -0.109 0.106 0.305 0.5162 0.897 0.729 1.1 -0.0464 0.107 0.664 0.1779 0.955 0.774 1.18 PRS_PLINK_2.51188643150958e.06 FALSE 612 Breast conditions, congenital or relating to hormones Both 315 1375 11 genitourinary black 1375, 315 344, 79 344, 74 343, 81 344, 81 0.0108 0.0642 0.866 0.06233 1.01 0.891 1.15 -0.0895 0.181 0.62 0.2075 0.914 0.642 1.3 -5.88e-05 0.177 1 0.0001151 1 0.707 1.42 0.0265 0.178 0.882 0.05464 1.03 0.724 1.46 PRS_PLINK_2.51188643150958e.06 FALSE 612.1 Galactorrhea Both 53 206 11 genitourinary black 206, 53 52, 18 51, 13 51, 15 52, 7 -0.432 0.426 0.31 0.5087 0.649 0.282 1.49 -0.208 0.407 0.608 0.216 0.812 0.366 1.8 -0.905 0.505 0.0731 1.136 0.404 0.15 1.09 PRS_PLINK_2.51188643150958e.06 FALSE 612.2 Hypertrophy of breast (Gynecomastia) Both 235 1023 11 genitourinary black 1023, 235 256, 57 256, 57 255, 57 256, 64 0.021 0.0757 0.781 0.1073 1.02 0.88 1.18 0.00759 0.208 0.971 0.01286 1.01 0.671 1.51 0.0176 0.208 0.932 0.03041 1.02 0.677 1.53 0.149 0.204 0.466 0.3311 1.16 0.778 1.73 PRS_PLINK_2.51188643150958e.06 FALSE 612.3 Congenital anomalies of breast Both 27 101 11 genitourinary black 101, 27 26, 4 25, 4 25, 9 25, 10 0.144 0.22 0.514 0.2893 1.15 0.75 1.78 0.665 0.992 0.503 0.2985 1.94 0.278 13.6 0.632 0.818 0.44 0.357 1.88 0.379 9.36 0.782 0.74 0.29 0.5375 2.19 0.513 9.32 PRS_PLINK_2.51188643150958e.06 TRUE 613 Other nonmalignant breast conditions Both 1174 3411 11 genitourinary black 3411, 1174 853, 299 853, 286 852, 311 853, 278 -0.0329 0.0343 0.337 0.4721 0.968 0.905 1.03 -0.0574 0.0969 0.554 0.2567 0.944 0.781 1.14 0.0228 0.0952 0.811 0.091 1.02 0.849 1.23 -0.0654 0.0977 0.503 0.2983 0.937 0.774 1.13 PRS_PLINK_2.51188643150958e.06 FALSE 613.1 Inflammatory disease of breast Both 162 927 11 genitourinary black 927, 162 232, 43 232, 38 231, 45 232, 36 -0.042 0.0873 0.631 0.2001 0.959 0.808 1.14 -0.104 0.241 0.667 0.1761 0.901 0.562 1.45 0.0466 0.233 0.842 0.0749 1.05 0.664 1.65 -0.182 0.246 0.459 0.3379 0.833 0.514 1.35 PRS_PLINK_2.51188643150958e.06 FALSE 613.5 Mastodynia Both 607 2581 11 genitourinary black 2581, 607 646, 159 645, 145 645, 156 645, 147 -0.0274 0.0445 0.539 0.2687 0.973 0.892 1.06 -0.0907 0.128 0.478 0.3204 0.913 0.711 1.17 -0.0248 0.126 0.844 0.07362 0.976 0.762 1.25 -0.0555 0.128 0.664 0.1778 0.946 0.736 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 613.7 Other signs and symptoms in breast Both 297 1405 11 genitourinary black 1405, 297 352, 84 351, 69 351, 89 351, 55 -0.0765 0.063 0.225 0.6483 0.926 0.819 1.05 -0.217 0.179 0.225 0.6487 0.805 0.567 1.14 0.0366 0.17 0.829 0.08121 1.04 0.743 1.45 -0.467 0.19 0.014 1.855 0.627 0.432 0.91 PRS_PLINK_2.51188643150958e.06 FALSE 613.8 Other specified disorders of breast Both 257 1422 11 genitourinary black 1422, 257 356, 76 355, 50 355, 75 356, 56 -0.094 0.0652 0.15 0.8251 0.91 0.801 1.03 -0.397 0.196 0.0432 1.365 0.672 0.458 0.988 -0.00855 0.179 0.962 0.01685 0.991 0.698 1.41 -0.31 0.191 0.105 0.9786 0.734 0.504 1.07 PRS_PLINK_2.51188643150958e.06 FALSE 613.9 Breast disorder NOS Both 403 2291 11 genitourinary black 2291, 403 573, 101 573, 110 572, 99 573, 93 0.0253 0.0557 0.65 0.1871 1.03 0.92 1.14 0.0734 0.15 0.625 0.2044 1.08 0.802 1.44 -0.0336 0.153 0.826 0.08316 0.967 0.717 1.3 -0.0816 0.156 0.6 0.2221 0.922 0.679 1.25 PRS_PLINK_2.51188643150958e.06 FALSE 614 Inflammatory diseases of female pelvic organs Female 1202 2854 11 genitourinary black 2854, 1202 714, 301 713, 284 713, 292 714, 325 0.0287 0.0349 0.412 0.3851 1.03 0.961 1.1 -0.0446 0.0997 0.654 0.1841 0.956 0.787 1.16 -0.00845 0.0988 0.932 0.03065 0.992 0.817 1.2 0.075 0.0972 0.44 0.3562 1.08 0.891 1.3 PRS_PLINK_2.51188643150958e.06 FALSE 614.1 Pelvic peritoneal adhesions, female (postoperative) (postinfection) Female 87 486 11 genitourinary black 486, 87 122, 20 121, 25 121, 21 122, 21 -0.0603 0.114 0.597 0.2243 0.941 0.753 1.18 0.194 0.33 0.556 0.2549 1.21 0.636 2.32 0.0768 0.337 0.82 0.08636 1.08 0.558 2.09 -0.0559 0.336 0.868 0.06155 0.946 0.49 1.83 PRS_PLINK_2.51188643150958e.06 FALSE 614.3 Pelvic inflammatory disease (PID) Female 156 673 11 genitourinary black 673, 156 169, 40 168, 32 168, 45 168, 39 0.0875 0.0942 0.353 0.4521 1.09 0.907 1.31 -0.181 0.264 0.494 0.3066 0.834 0.497 1.4 0.226 0.249 0.364 0.4394 1.25 0.77 2.04 0.0283 0.253 0.911 0.04058 1.03 0.627 1.69 PRS_PLINK_2.51188643150958e.06 FALSE 614.31 Acute inflammatory pelvic disease Female 33 121 11 genitourinary black 121, 33 31, 6 30, 6 30, 10 30, 11 0.39 0.221 0.0772 1.113 1.48 0.958 2.28 -0.0366 0.679 0.957 0.01909 0.964 0.255 3.65 0.98 0.708 0.166 0.7794 2.66 0.665 10.7 0.736 0.571 0.197 0.7048 2.09 0.682 6.39 PRS_PLINK_2.51188643150958e.06 TRUE 614.32 Chronic inflammatory pelvic disease Female 58 269 11 genitourinary black 269, 58 68, 14 67, 13 67, 16 67, 15 0.162 0.163 0.322 0.4927 1.18 0.854 1.62 0.0271 0.431 0.95 0.02235 1.03 0.442 2.39 0.26 0.419 0.535 0.2714 1.3 0.57 2.95 0.0458 0.41 0.911 0.04045 1.05 0.469 2.34 PRS_PLINK_2.51188643150958e.06 FALSE 614.33 Pelvic inflammatory disease, NOS Female 85 330 11 genitourinary black 330, 85 83, 18 82, 17 82, 24 83, 26 0.219 0.138 0.114 0.9423 1.24 0.949 1.63 -0.0399 0.372 0.915 0.0388 0.961 0.463 1.99 0.426 0.359 0.235 0.6292 1.53 0.758 3.1 0.462 0.355 0.193 0.7138 1.59 0.791 3.19 PRS_PLINK_2.51188643150958e.06 FALSE 614.4 Inflammatory diseases of uterus, except cervix Female 43 251 11 genitourinary black 251, 43 63, 15 63, 11 62, 7 63, 10 -0.108 0.152 0.476 0.322 0.898 0.667 1.21 -0.576 0.463 0.213 0.6708 0.562 0.227 1.39 -0.891 0.517 0.0845 1.073 0.41 0.149 1.13 -0.184 0.45 0.683 0.1658 0.832 0.344 2.01 PRS_PLINK_2.51188643150958e.06 TRUE 614.5 Inflammatory disease of cervix, vagina, and vulva Female 1071 2828 11 genitourinary black 2828, 1071 707, 270 707, 254 707, 255 707, 292 0.0273 0.0365 0.456 0.3413 1.03 0.957 1.1 -0.0471 0.104 0.649 0.1875 0.954 0.779 1.17 -0.0389 0.103 0.706 0.1512 0.962 0.786 1.18 0.0777 0.101 0.442 0.355 1.08 0.887 1.32 PRS_PLINK_2.51188643150958e.06 FALSE 614.51 Cervicitis and endocervicitis Female 83 361 11 genitourinary black 361, 83 91, 17 90, 16 90, 25 90, 25 0.205 0.129 0.113 0.9454 1.23 0.952 1.58 -0.433 0.401 0.28 0.5521 0.649 0.295 1.42 0.3 0.352 0.394 0.4045 1.35 0.677 2.69 0.292 0.347 0.401 0.3967 1.34 0.678 2.65 PRS_PLINK_2.51188643150958e.06 FALSE 614.52 Vaginitis and vulvovaginitis Female 953 2723 11 genitourinary black 2723, 953 681, 239 681, 231 680, 226 681, 257 0.0168 0.0379 0.658 0.182 1.02 0.944 1.1 -0.0216 0.108 0.841 0.07508 0.979 0.792 1.21 -0.0393 0.108 0.716 0.145 0.961 0.778 1.19 0.0739 0.106 0.486 0.3135 1.08 0.875 1.33 PRS_PLINK_2.51188643150958e.06 FALSE 614.53 Cyst or abscess of Bartholin's gland Female 47 205 11 genitourinary black 205, 47 52, 11 51, 7 51, 13 51, 16 0.24 0.207 0.248 0.6059 1.27 0.846 1.91 -0.419 0.502 0.403 0.3945 0.657 0.246 1.76 0.174 0.479 0.717 0.1444 1.19 0.465 3.04 0.258 0.439 0.557 0.254 1.29 0.547 3.06 PRS_PLINK_2.51188643150958e.06 TRUE 614.54 Abscess or ulceration of vulva Female 72 348 11 genitourinary black 348, 72 87, 25 87, 11 87, 17 87, 19 0.0195 0.123 0.874 0.05833 1.02 0.801 1.3 -0.779 0.385 0.0427 1.37 0.459 0.216 0.975 -0.355 0.348 0.308 0.512 0.701 0.354 1.39 -0.353 0.343 0.303 0.518 0.702 0.358 1.38 PRS_PLINK_2.51188643150958e.06 FALSE 615 Endometriosis Female 402 2076 11 genitourinary black 2076, 402 519, 98 519, 105 519, 106 519, 93 0.0142 0.0547 0.795 0.09972 1.01 0.911 1.13 0.0728 0.153 0.635 0.1972 1.08 0.796 1.45 0.109 0.154 0.477 0.3219 1.12 0.826 1.51 -0.0466 0.158 0.768 0.1149 0.955 0.701 1.3 PRS_PLINK_2.51188643150958e.06 FALSE 618 Genital prolapse Female 567 3125 11 genitourinary black 3125, 567 782, 149 781, 146 781, 160 781, 112 -0.0324 0.0462 0.483 0.3161 0.968 0.884 1.06 -0.0324 0.127 0.799 0.09751 0.968 0.755 1.24 0.073 0.125 0.558 0.253 1.08 0.842 1.37 -0.274 0.136 0.0435 1.362 0.76 0.583 0.992 PRS_PLINK_2.51188643150958e.06 FALSE 618.1 Prolapse of vaginal walls Female 323 2372 11 genitourinary black 2372, 323 593, 95 593, 82 593, 88 593, 58 -0.0863 0.0592 0.145 0.8386 0.917 0.817 1.03 -0.16 0.161 0.319 0.4955 0.852 0.621 1.17 -0.0789 0.159 0.619 0.208 0.924 0.677 1.26 -0.488 0.177 0.00573 2.242 0.614 0.434 0.868 PRS_PLINK_2.51188643150958e.06 FALSE 618.2 Uterine/Uterovaginal prolapse Female 141 954 11 genitourinary black 954, 141 239, 36 238, 29 238, 44 239, 32 0.0681 0.0981 0.487 0.3123 1.07 0.883 1.3 -0.188 0.263 0.474 0.3244 0.828 0.495 1.39 0.204 0.242 0.399 0.3986 1.23 0.763 1.97 -0.0969 0.263 0.713 0.1471 0.908 0.542 1.52 PRS_PLINK_2.51188643150958e.06 FALSE 618.5 Prolapse of vaginal vault after hysterectomy Female 36 550 11 genitourinary black 550, 36 138, 10 137, 11 137, 7 138, 8 0.0112 0.176 0.949 0.0226 1.01 0.716 1.43 0.141 0.44 0.749 0.1258 1.15 0.486 2.72 -0.288 0.481 0.549 0.2606 0.749 0.292 1.92 -0.0212 0.507 0.967 0.01477 0.979 0.363 2.64 PRS_PLINK_2.51188643150958e.06 TRUE 618.6 Vaginal enterocele, congenital or acquired Female 158 753 11 genitourinary black 753, 158 189, 49 188, 38 188, 36 188, 35 -0.0299 0.0845 0.724 0.1403 0.971 0.822 1.15 -0.234 0.241 0.332 0.4794 0.792 0.494 1.27 -0.252 0.244 0.301 0.5218 0.777 0.482 1.25 -0.277 0.244 0.256 0.5912 0.758 0.47 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 619 Noninflammatory female genital disorders Female 1577 2719 11 genitourinary black 2719, 1577 680, 379 680, 393 679, 387 680, 418 0.0673 0.0328 0.04 1.398 1.07 1 1.14 0.0594 0.0914 0.515 0.2879 1.06 0.887 1.27 0.0516 0.0917 0.574 0.2412 1.05 0.88 1.26 0.0971 0.0907 0.284 0.5467 1.1 0.923 1.32 PRS_PLINK_2.51188643150958e.06 FALSE 619.1 Noninflammatory disorders of ovary, fallopian tube, and broad ligament Female 347 1642 11 genitourinary black 1642, 347 411, 73 410, 83 410, 100 411, 91 0.122 0.0626 0.0516 1.287 1.13 0.999 1.28 0.139 0.176 0.429 0.3678 1.15 0.814 1.62 0.377 0.171 0.0274 1.562 1.46 1.04 2.04 0.251 0.173 0.147 0.8313 1.29 0.915 1.81 PRS_PLINK_2.51188643150958e.06 FALSE 619.2 Disorders of uterus, NEC Female 186 844 11 genitourinary black 844, 186 211, 37 211, 50 211, 51 211, 48 0.143 0.0843 0.09 1.046 1.15 0.978 1.36 0.24 0.238 0.312 0.5059 1.27 0.798 2.03 0.364 0.24 0.129 0.8895 1.44 0.9 2.3 0.264 0.238 0.268 0.5719 1.3 0.816 2.08 PRS_PLINK_2.51188643150958e.06 FALSE 619.3 Noninflammatory disorders of cervix Female 125 660 11 genitourinary black 660, 125 165, 33 165, 33 165, 24 165, 35 0.0123 0.0902 0.892 0.04986 1.01 0.848 1.21 0.00402 0.273 0.988 0.005132 1 0.588 1.71 -0.365 0.29 0.208 0.682 0.695 0.394 1.22 0.061 0.265 0.818 0.08715 1.06 0.632 1.79 PRS_PLINK_2.51188643150958e.06 FALSE 619.4 Noninflammatory disorders of vagina Female 762 2656 11 genitourinary black 2656, 762 664, 193 664, 185 664, 180 664, 204 0.0651 0.0423 0.124 0.9077 1.07 0.982 1.16 -0.0182 0.118 0.877 0.05684 0.982 0.779 1.24 -0.0263 0.119 0.825 0.08365 0.974 0.772 1.23 0.0709 0.116 0.542 0.2658 1.07 0.855 1.35 PRS_PLINK_2.51188643150958e.06 FALSE 619.5 Noninflammatory disorders of vulva and perineum Female 414 1741 11 genitourinary black 1741, 414 436, 111 435, 97 435, 93 435, 113 0.0174 0.0539 0.747 0.1266 1.02 0.916 1.13 -0.112 0.155 0.47 0.328 0.894 0.66 1.21 -0.151 0.157 0.336 0.4734 0.86 0.633 1.17 0.02 0.151 0.894 0.04848 1.02 0.759 1.37 PRS_PLINK_2.51188643150958e.06 FALSE 620 Dysplasia of female genital organs Female 115 640 11 genitourinary black 640, 115 160, 25 160, 20 160, 36 160, 34 0.114 0.108 0.292 0.5343 1.12 0.907 1.38 -0.158 0.316 0.616 0.2101 0.854 0.459 1.59 0.375 0.283 0.186 0.731 1.45 0.835 2.54 0.345 0.288 0.231 0.6367 1.41 0.803 2.48 PRS_PLINK_2.51188643150958e.06 FALSE 620.1 Dysplasia of cervix Female 43 274 11 genitourinary black 274, 43 69, 13 68, 8 68, 16 69, 6 -0.169 0.159 0.286 0.5433 0.844 0.619 1.15 -0.522 0.489 0.286 0.5433 0.594 0.228 1.55 0.199 0.417 0.634 0.1981 1.22 0.539 2.76 -0.911 0.533 0.0877 1.057 0.402 0.141 1.14 PRS_PLINK_2.51188643150958e.06 TRUE 621 Endometrial hyperplasia Female 131 704 11 genitourinary black 704, 131 176, 21 176, 34 176, 36 176, 40 0.219 0.106 0.0383 1.417 1.25 1.01 1.53 0.451 0.298 0.129 0.8878 1.57 0.876 2.81 0.528 0.289 0.0677 1.17 1.7 0.962 2.99 0.595 0.287 0.0379 1.421 1.81 1.03 3.18 PRS_PLINK_2.51188643150958e.06 FALSE 622 Polyp of female genital organs Female 441 2384 11 genitourinary black 2384, 441 596, 99 596, 117 596, 94 596, 131 0.061 0.056 0.277 0.558 1.06 0.952 1.19 0.147 0.15 0.326 0.4873 1.16 0.864 1.55 -0.0388 0.155 0.803 0.09538 0.962 0.71 1.3 0.286 0.146 0.0498 1.303 1.33 1 1.77 PRS_PLINK_2.51188643150958e.06 FALSE 622.1 Polyp of corpus uteri Female 350 1873 11 genitourinary black 1873, 350 469, 83 468, 96 468, 75 468, 96 0.0218 0.0618 0.724 0.14 1.02 0.905 1.15 0.128 0.166 0.442 0.3548 1.14 0.82 1.57 -0.0964 0.172 0.576 0.2394 0.908 0.648 1.27 0.15 0.165 0.363 0.4405 1.16 0.841 1.6 PRS_PLINK_2.51188643150958e.06 FALSE 622.2 Mucous polyp of cervix Female 131 759 11 genitourinary black 759, 131 190, 32 190, 27 189, 25 190, 47 0.107 0.106 0.313 0.5048 1.11 0.904 1.37 -0.149 0.279 0.593 0.2269 0.861 0.498 1.49 -0.242 0.283 0.391 0.4075 0.785 0.451 1.37 0.33 0.253 0.192 0.7173 1.39 0.847 2.28 PRS_PLINK_2.51188643150958e.06 FALSE 623 Hypertrophy of female genital organs Female 269 1370 11 genitourinary black 1370, 269 343, 77 342, 66 342, 52 343, 74 -0.0248 0.0644 0.7 0.1551 0.975 0.86 1.11 -0.145 0.186 0.436 0.3607 0.865 0.6 1.25 -0.384 0.195 0.049 1.31 0.681 0.465 0.998 -0.0537 0.18 0.766 0.1158 0.948 0.665 1.35 PRS_PLINK_2.51188643150958e.06 FALSE 624 Symptoms involving female genital tract Female 404 1584 11 genitourinary black 1584, 404 396, 83 396, 116 396, 102 396, 103 0.0932 0.058 0.108 0.9655 1.1 0.98 1.23 0.328 0.162 0.0429 1.368 1.39 1.01 1.91 0.247 0.166 0.137 0.8626 1.28 0.924 1.77 0.21 0.165 0.204 0.6896 1.23 0.892 1.71 PRS_PLINK_2.51188643150958e.06 FALSE 624.1 Dystrophy of female genital tract Female 71 305 11 genitourinary black 305, 71 77, 13 76, 21 76, 16 76, 21 0.236 0.152 0.12 0.9199 1.27 0.94 1.7 0.482 0.387 0.214 0.6703 1.62 0.758 3.46 0.14 0.409 0.732 0.1357 1.15 0.517 2.56 0.438 0.382 0.251 0.5995 1.55 0.733 3.28 PRS_PLINK_2.51188643150958e.06 FALSE 624.2 Atrophy of female genital tract Female 23 102 11 genitourinary black 102, 23 26, 7 25, 6 25, 7 26, 3 -0.327 0.235 0.164 0.7847 0.721 0.455 1.14 -0.281 0.643 0.663 0.1787 0.755 0.214 2.66 -0.109 0.652 0.867 0.06207 0.896 0.25 3.22 -0.62 0.707 0.38 0.4197 0.538 0.134 2.15 PRS_PLINK_2.51188643150958e.06 TRUE 624.9 stress incontinence, female Female 564 2068 11 genitourinary black 2068, 564 517, 117 517, 153 517, 152 517, 142 0.0667 0.0495 0.178 0.7494 1.07 0.97 1.18 0.256 0.138 0.0648 1.188 1.29 0.984 1.69 0.247 0.138 0.074 1.131 1.28 0.976 1.68 0.149 0.141 0.289 0.5397 1.16 0.881 1.53 PRS_PLINK_2.51188643150958e.06 FALSE 625 Pain and other symptoms associated with female genital organs Female 1723 2233 11 genitourinary black 2233, 1723 559, 380 558, 441 558, 425 558, 477 0.085 0.0328 0.00945 2.024 1.09 1.02 1.16 0.155 0.0935 0.0982 1.008 1.17 0.972 1.4 0.126 0.0942 0.181 0.7421 1.13 0.943 1.36 0.235 0.0924 0.011 1.96 1.27 1.06 1.52 PRS_PLINK_2.51188643150958e.06 FALSE 625.1 Dyspareunia Female 345 1536 11 genitourinary black 1536, 345 384, 79 384, 87 384, 80 384, 99 0.062 0.0607 0.307 0.513 1.06 0.945 1.2 0.093 0.172 0.59 0.2293 1.1 0.783 1.54 0.00881 0.174 0.96 0.01789 1.01 0.717 1.42 0.22 0.168 0.189 0.7229 1.25 0.897 1.73 PRS_PLINK_2.51188643150958e.06 FALSE 626 Disorders of menstruation and other abnormal bleeding from female genital tract Female 1647 1811 11 genitourinary black 1811, 1647 453, 384 453, 420 452, 403 453, 440 0.0564 0.0362 0.119 0.9228 1.06 0.986 1.14 0.158 0.102 0.121 0.9158 1.17 0.959 1.43 0.109 0.103 0.292 0.5346 1.11 0.911 1.36 0.154 0.102 0.129 0.8894 1.17 0.956 1.42 PRS_PLINK_2.51188643150958e.06 FALSE 626.1 Irregular menstrual cycle/bleeding Female 1319 1658 11 genitourinary black 1658, 1319 415, 301 414, 344 414, 312 415, 362 0.0813 0.0395 0.0396 1.402 1.08 1 1.17 0.212 0.11 0.0542 1.266 1.24 0.996 1.53 0.109 0.113 0.332 0.479 1.12 0.895 1.39 0.222 0.109 0.043 1.366 1.25 1.01 1.55 PRS_PLINK_2.51188643150958e.06 FALSE 626.11 Absent or infrequent menstruation Female 337 878 11 genitourinary black 878, 337 220, 77 219, 84 219, 84 220, 92 0.0976 0.0684 0.154 0.8137 1.1 0.964 1.26 0.127 0.188 0.5 0.3011 1.14 0.785 1.64 0.107 0.188 0.572 0.2429 1.11 0.769 1.61 0.187 0.184 0.309 0.5095 1.21 0.84 1.73 PRS_PLINK_2.51188643150958e.06 FALSE 626.12 Excessive or frequent menstruation Female 703 1289 11 genitourinary black 1289, 703 323, 163 322, 178 322, 164 322, 198 0.0902 0.0494 0.0675 1.171 1.09 0.994 1.21 0.12 0.137 0.38 0.42 1.13 0.862 1.47 0.0325 0.14 0.816 0.08817 1.03 0.785 1.36 0.214 0.134 0.11 0.9573 1.24 0.952 1.61 PRS_PLINK_2.51188643150958e.06 FALSE 626.13 Irregular menstrual cycle Female 628 1327 11 genitourinary black 1327, 628 332, 145 332, 167 331, 147 332, 169 0.0698 0.0511 0.172 0.7641 1.07 0.97 1.19 0.162 0.14 0.25 0.6023 1.18 0.893 1.55 0.113 0.145 0.438 0.3588 1.12 0.842 1.49 0.191 0.141 0.175 0.7565 1.21 0.918 1.6 PRS_PLINK_2.51188643150958e.06 FALSE 626.14 Irregular menstrual bleeding Female 315 961 11 genitourinary black 961, 315 241, 58 240, 90 240, 77 240, 90 0.186 0.0722 0.0098 2.009 1.2 1.05 1.39 0.449 0.193 0.0203 1.693 1.57 1.07 2.29 0.302 0.199 0.129 0.8898 1.35 0.916 2 0.425 0.193 0.0272 1.566 1.53 1.05 2.23 PRS_PLINK_2.51188643150958e.06 FALSE 626.15 Infertility, female, associated with anovulation Female 112 417 11 genitourinary black 417, 112 105, 22 104, 29 104, 29 104, 32 0.137 0.112 0.22 0.6583 1.15 0.921 1.43 0.164 0.325 0.613 0.2125 1.18 0.623 2.23 0.282 0.322 0.381 0.4194 1.33 0.706 2.49 0.383 0.315 0.224 0.6497 1.47 0.791 2.72 PRS_PLINK_2.51188643150958e.06 FALSE 626.2 Dysmenorrhea Female 386 1022 11 genitourinary black 1022, 386 256, 94 255, 95 255, 100 256, 97 0.0907 0.0639 0.156 0.8074 1.09 0.966 1.24 0.0708 0.175 0.686 0.1637 1.07 0.762 1.51 0.133 0.175 0.449 0.348 1.14 0.81 1.61 0.0809 0.174 0.643 0.1919 1.08 0.77 1.53 PRS_PLINK_2.51188643150958e.06 FALSE 626.4 Premenstrual tension syndromes Female 107 363 11 genitourinary black 363, 107 91, 25 91, 32 90, 30 91, 20 -0.0038 0.104 0.971 0.01279 0.996 0.812 1.22 0.212 0.309 0.493 0.3076 1.24 0.674 2.27 0.16 0.311 0.608 0.2159 1.17 0.637 2.16 -0.085 0.339 0.802 0.09565 0.919 0.472 1.79 PRS_PLINK_2.51188643150958e.06 FALSE 626.8 Infertility, female Female 214 709 11 genitourinary black 709, 214 178, 49 177, 46 177, 59 177, 60 0.108 0.0801 0.176 0.755 1.11 0.953 1.3 -0.00461 0.237 0.985 0.006782 0.995 0.625 1.58 0.253 0.226 0.262 0.5809 1.29 0.827 2.01 0.225 0.224 0.316 0.4997 1.25 0.807 1.94 PRS_PLINK_2.51188643150958e.06 FALSE 627 Menopausal and postmenopausal disorders Female 1474 1751 11 genitourinary black 1751, 1474 438, 342 438, 372 437, 372 438, 388 0.0387 0.0361 0.284 0.547 1.04 0.968 1.12 0.07 0.103 0.496 0.3043 1.07 0.877 1.31 0.0812 0.102 0.427 0.3695 1.08 0.888 1.33 0.141 0.102 0.166 0.7801 1.15 0.943 1.41 PRS_PLINK_2.51188643150958e.06 FALSE 627.1 Postmenopausal bleeding Female 418 1306 11 genitourinary black 1306, 418 327, 88 326, 117 326, 108 327, 105 0.0557 0.0609 0.36 0.4432 1.06 0.938 1.19 0.284 0.165 0.0856 1.068 1.33 0.961 1.84 0.24 0.166 0.148 0.8309 1.27 0.919 1.76 0.199 0.167 0.231 0.6357 1.22 0.881 1.69 PRS_PLINK_2.51188643150958e.06 FALSE 627.2 Symptomatic menopause Female 1009 1678 11 genitourinary black 1678, 1009 420, 239 419, 254 419, 252 420, 264 0.00895 0.0398 0.822 0.08499 1.01 0.933 1.09 0.0741 0.116 0.522 0.2827 1.08 0.859 1.35 0.0535 0.115 0.642 0.1921 1.05 0.842 1.32 0.118 0.115 0.303 0.5185 1.13 0.899 1.41 PRS_PLINK_2.51188643150958e.06 FALSE 627.21 Symptomatic artificial menopause Female 49 177 11 genitourinary black 177, 49 45, 16 44, 12 44, 10 44, 11 -0.0777 0.147 0.597 0.2238 0.925 0.693 1.23 -0.244 0.452 0.59 0.2291 0.784 0.323 1.9 -0.423 0.465 0.363 0.4401 0.655 0.263 1.63 -0.229 0.443 0.605 0.2185 0.795 0.334 1.89 PRS_PLINK_2.51188643150958e.06 TRUE 627.22 Need for Hormone replacement therapy (postmenopausal) Female 134 504 11 genitourinary black 504, 134 126, 40 126, 31 126, 25 126, 38 -0.119 0.0902 0.186 0.7312 0.887 0.744 1.06 -0.157 0.28 0.575 0.24 0.855 0.494 1.48 -0.34 0.29 0.24 0.6192 0.712 0.404 1.26 0.0263 0.267 0.921 0.03554 1.03 0.608 1.73 PRS_PLINK_2.51188643150958e.06 FALSE 627.3 Postmenopausal atrophic vaginitis Female 337 1217 11 genitourinary black 1217, 337 305, 102 304, 82 304, 80 304, 73 -0.0627 0.0643 0.329 0.4824 0.939 0.828 1.07 -0.197 0.171 0.249 0.6035 0.821 0.587 1.15 -0.242 0.171 0.156 0.8059 0.785 0.561 1.1 -0.338 0.176 0.0547 1.262 0.713 0.505 1.01 PRS_PLINK_2.51188643150958e.06 FALSE 627.4 Premenopausal menorrhagia Female 132 412 11 genitourinary black 412, 132 103, 26 103, 34 103, 38 103, 34 0.115 0.116 0.323 0.4908 1.12 0.893 1.41 0.226 0.299 0.451 0.3462 1.25 0.697 2.25 0.256 0.295 0.385 0.4149 1.29 0.725 2.3 0.297 0.3 0.323 0.4906 1.35 0.747 2.42 PRS_PLINK_2.51188643150958e.06 FALSE 627.5 Premature menopause and other ovarian failure Female 87 368 11 genitourinary black 368, 87 92, 25 92, 22 92, 19 92, 21 -0.111 0.115 0.335 0.4746 0.895 0.715 1.12 -0.315 0.335 0.347 0.4597 0.73 0.378 1.41 -0.336 0.345 0.329 0.4827 0.714 0.364 1.4 -0.3 0.34 0.377 0.4239 0.741 0.38 1.44 PRS_PLINK_2.51188643150958e.06 FALSE 628 Ovarian cyst Female 623 1549 11 genitourinary black 1549, 623 388, 131 387, 167 387, 162 387, 163 0.0854 0.0502 0.0887 1.052 1.09 0.987 1.2 0.279 0.14 0.0467 1.331 1.32 1 1.74 0.27 0.141 0.0547 1.262 1.31 0.995 1.73 0.236 0.14 0.0918 1.037 1.27 0.962 1.67 PRS_PLINK_2.51188643150958e.06 FALSE 634 Miscarriage; stillbirth Female 221 1239 12 pregnancy complications royalblue4 1239, 221 310, 43 310, 60 309, 57 310, 61 0.0406 0.0708 0.567 0.2467 1.04 0.906 1.2 0.364 0.216 0.0928 1.032 1.44 0.941 2.2 0.309 0.218 0.157 0.8051 1.36 0.888 2.09 0.397 0.216 0.0663 1.179 1.49 0.974 2.27 PRS_PLINK_2.51188643150958e.06 FALSE 634.1 Missed abortion/Hydatidiform mole Female 72 424 12 pregnancy complications royalblue4 424, 72 106, 9 106, 22 106, 21 106, 20 0.205 0.143 0.153 0.8155 1.23 0.927 1.62 0.903 0.418 0.0307 1.513 2.47 1.09 5.59 0.741 0.41 0.0705 1.152 2.1 0.94 4.68 0.711 0.408 0.0817 1.088 2.04 0.914 4.53 PRS_PLINK_2.51188643150958e.06 FALSE 634.3 Ectopic pregnancy Female 21 172 12 pregnancy complications royalblue4 172, 21 43, 5 43, 3 43, 5 43, 8 0.104 0.245 0.671 0.173 1.11 0.686 1.79 -0.163 0.739 0.826 0.08323 0.85 0.2 3.62 -0.177 0.749 0.813 0.08978 0.838 0.193 3.64 0.747 0.676 0.269 0.57 2.11 0.561 7.95 PRS_PLINK_2.51188643150958e.06 TRUE 635 Hemorrhage during pregnancy; childbirth and postpartum Female 120 793 12 pregnancy complications royalblue4 793, 120 199, 24 198, 31 198, 32 198, 33 0.039 0.0956 0.683 0.1654 1.04 0.862 1.25 0.239 0.287 0.405 0.3928 1.27 0.724 2.23 0.304 0.288 0.291 0.5365 1.36 0.771 2.38 0.354 0.285 0.214 0.6699 1.42 0.815 2.49 PRS_PLINK_2.51188643150958e.06 FALSE 635.2 Antepartum hemorrhage, abruptio placentae, and placenta previa Female 84 563 12 pregnancy complications royalblue4 563, 84 141, 19 141, 21 140, 22 141, 22 0.0822 0.114 0.47 0.3274 1.09 0.868 1.36 0.164 0.339 0.628 0.2019 1.18 0.606 2.29 0.181 0.338 0.592 0.2274 1.2 0.618 2.33 0.217 0.334 0.517 0.2867 1.24 0.645 2.39 PRS_PLINK_2.51188643150958e.06 FALSE 635.3 Placenta previa and abruptio placenta Female 53 418 12 pregnancy complications royalblue4 418, 53 105, 10 104, 10 104, 19 105, 14 -0.0172 0.134 0.898 0.04651 0.983 0.755 1.28 0.0669 0.452 0.882 0.05446 1.07 0.441 2.59 0.485 0.401 0.226 0.6463 1.62 0.741 3.56 0.449 0.422 0.288 0.541 1.57 0.685 3.59 PRS_PLINK_2.51188643150958e.06 FALSE 636 Early or threatened labor; hemorrhage in early pregnancy Female 272 1194 12 pregnancy complications royalblue4 1194, 272 299, 53 298, 70 298, 79 299, 70 0.0901 0.0703 0.2 0.6991 1.09 0.953 1.26 0.27 0.203 0.184 0.7348 1.31 0.879 1.95 0.465 0.198 0.0191 1.719 1.59 1.08 2.35 0.312 0.201 0.121 0.918 1.37 0.921 2.03 PRS_PLINK_2.51188643150958e.06 FALSE 636.1 Threatened premature labor Female 94 576 12 pregnancy complications royalblue4 576, 94 144, 15 144, 26 144, 35 144, 18 0.0813 0.112 0.468 0.3299 1.08 0.871 1.35 0.458 0.342 0.181 0.7411 1.58 0.808 3.09 0.887 0.336 0.00837 2.077 2.43 1.26 4.69 0.224 0.37 0.545 0.2639 1.25 0.606 2.58 PRS_PLINK_2.51188643150958e.06 FALSE 636.2 Early onset of delivery Female 83 440 12 pregnancy complications royalblue4 440, 83 110, 24 110, 16 110, 25 110, 18 -0.0997 0.108 0.356 0.4487 0.905 0.732 1.12 -0.427 0.346 0.217 0.6626 0.653 0.331 1.29 0.0662 0.324 0.838 0.07661 1.07 0.566 2.02 -0.278 0.339 0.411 0.3858 0.757 0.39 1.47 PRS_PLINK_2.51188643150958e.06 FALSE 636.3 Hemorrhage in early pregnancy Female 115 642 12 pregnancy complications royalblue4 642, 115 161, 19 160, 32 160, 33 161, 31 0.177 0.105 0.09 1.046 1.19 0.973 1.47 0.557 0.313 0.0752 1.124 1.75 0.945 3.23 0.569 0.309 0.0655 1.183 1.77 0.964 3.23 0.535 0.311 0.0857 1.067 1.71 0.928 3.15 PRS_PLINK_2.51188643150958e.06 FALSE 636.8 Cervical incompetence Female 23 134 12 pregnancy complications royalblue4 134, 23 34, 4 33, 6 33, 9 34, 4 0.0321 0.238 0.893 0.04936 1.03 0.648 1.65 0.0281 0.694 0.968 0.01427 1.03 0.264 4.01 0.691 0.629 0.271 0.5663 2 0.582 6.85 -0.365 0.732 0.618 0.2093 0.694 0.165 2.91 PRS_PLINK_2.51188643150958e.06 TRUE 637 Short gestation; low birth weight; and fetal growth retardation Both 30 129 12 pregnancy complications royalblue4 129, 30 33, 8 32, 9 32, 9 32, 4 -0.313 0.21 0.136 0.8654 0.731 0.485 1.1 0.106 0.563 0.85 0.07038 1.11 0.369 3.35 -0.0064 0.555 0.991 0.004017 0.994 0.335 2.95 -0.629 0.633 0.32 0.4949 0.533 0.154 1.84 PRS_PLINK_2.51188643150958e.06 TRUE 642 Hypertension complicating pregnancy, childbirth, and the puerperium Female 166 869 12 pregnancy complications royalblue4 869, 166 218, 43 217, 44 217, 40 217, 39 -0.0486 0.0829 0.557 0.2539 0.953 0.81 1.12 0.0232 0.235 0.921 0.03552 1.02 0.646 1.62 -0.0919 0.242 0.704 0.1524 0.912 0.568 1.47 -0.064 0.243 0.793 0.101 0.938 0.582 1.51 PRS_PLINK_2.51188643150958e.06 FALSE 642.1 Preeclampsia and eclampsia Female 94 467 12 pregnancy complications royalblue4 467, 94 117, 20 117, 23 116, 29 117, 22 -0.0413 0.106 0.697 0.1565 0.96 0.779 1.18 0.151 0.328 0.645 0.1907 1.16 0.611 2.21 0.412 0.322 0.202 0.6954 1.51 0.802 2.84 0.213 0.35 0.543 0.2651 1.24 0.623 2.46 PRS_PLINK_2.51188643150958e.06 FALSE 643 Excessive vomiting in pregnancy Female 66 382 12 pregnancy complications royalblue4 382, 66 96, 14 95, 22 95, 15 96, 15 -0.00329 0.135 0.981 0.008536 0.997 0.765 1.3 0.417 0.363 0.25 0.6023 1.52 0.746 3.09 0.0468 0.393 0.905 0.04324 1.05 0.485 2.26 0.065 0.396 0.87 0.06072 1.07 0.491 2.32 PRS_PLINK_2.51188643150958e.06 FALSE 643.1 Hyperemesis gravidarum Female 37 195 12 pregnancy complications royalblue4 195, 37 49, 5 49, 17 48, 7 49, 8 0.152 0.201 0.448 0.3485 1.16 0.786 1.73 1.08 0.528 0.0416 1.381 2.93 1.04 8.25 0.294 0.591 0.619 0.2083 1.34 0.421 4.28 0.354 0.595 0.552 0.2583 1.43 0.444 4.58 PRS_PLINK_2.51188643150958e.06 TRUE 644 Anemia during pregnancy Female 57 308 12 pregnancy complications royalblue4 308, 57 77, 13 77, 10 77, 17 77, 17 0.176 0.149 0.237 0.6254 1.19 0.891 1.6 -0.271 0.439 0.536 0.2705 0.762 0.323 1.8 0.177 0.397 0.655 0.1836 1.19 0.549 2.6 0.227 0.404 0.574 0.2413 1.26 0.569 2.77 PRS_PLINK_2.51188643150958e.06 FALSE 646 Other complications of pregnancy NEC Female 210 924 12 pregnancy complications royalblue4 924, 210 231, 46 231, 63 231, 54 231, 47 0.00894 0.0749 0.905 0.0434 1.01 0.871 1.17 0.281 0.217 0.195 0.709 1.33 0.865 2.03 0.166 0.223 0.456 0.3409 1.18 0.763 1.83 0.0671 0.229 0.769 0.114 1.07 0.683 1.67 PRS_PLINK_2.51188643150958e.06 FALSE 647 Infectious and parasitic complications affecting pregnancy Female 37 350 12 pregnancy complications royalblue4 350, 37 88, 9 87, 11 87, 10 88, 7 -0.0554 0.146 0.705 0.1519 0.946 0.71 1.26 0.199 0.471 0.673 0.172 1.22 0.485 3.07 0.0462 0.471 0.922 0.03529 1.05 0.416 2.64 -0.297 0.501 0.553 0.257 0.743 0.278 1.98 PRS_PLINK_2.51188643150958e.06 TRUE 647.1 Infections of genitourinary tract during pregnancy Female 56 332 12 pregnancy complications royalblue4 332, 56 83, 10 83, 14 83, 22 83, 10 -0.0488 0.131 0.709 0.1493 0.952 0.737 1.23 0.305 0.426 0.474 0.3244 1.36 0.588 3.13 0.788 0.4 0.0485 1.314 2.2 1.01 4.81 -0.0784 0.453 0.863 0.06423 0.925 0.381 2.25 PRS_PLINK_2.51188643150958e.06 FALSE 647.3 Major puerperal infection Female 10 88 12 pregnancy complications royalblue4 88, 10 22, 1 22, 3 22, 4 22, 2 0.0123 0.276 0.964 0.01575 1.01 0.589 1.74 1.92 1.41 0.173 0.7621 6.85 0.43 109 1.74 1.26 0.167 0.7762 5.71 0.481 67.7 0.106 1.03 0.918 0.03715 1.11 0.148 8.33 PRS_PLINK_2.51188643150958e.06 TRUE 649 Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium Female 319 1167 12 pregnancy complications royalblue4 1167, 319 292, 67 292, 91 291, 78 292, 83 0.101 0.0659 0.124 0.9053 1.11 0.973 1.26 0.265 0.185 0.151 0.8205 1.3 0.908 1.87 0.177 0.191 0.355 0.4495 1.19 0.821 1.73 0.255 0.187 0.172 0.7641 1.29 0.895 1.86 PRS_PLINK_2.51188643150958e.06 FALSE 649.1 Diabetes or abnormal glucose tolerance complicating pregnancy Female 215 956 12 pregnancy complications royalblue4 956, 215 239, 53 239, 55 239, 52 239, 55 -0.0433 0.0721 0.548 0.2613 0.958 0.831 1.1 0.0117 0.218 0.957 0.01893 1.01 0.66 1.55 -0.031 0.218 0.887 0.05215 0.969 0.633 1.49 -0.0248 0.217 0.909 0.04135 0.976 0.637 1.49 PRS_PLINK_2.51188643150958e.06 FALSE 653 Problems associated with amniotic cavity and membranes Female 129 860 12 pregnancy complications royalblue4 860, 129 215, 22 215, 33 215, 42 215, 32 0.186 0.101 0.0671 1.173 1.2 0.987 1.47 0.339 0.29 0.243 0.6144 1.4 0.795 2.48 0.665 0.279 0.0172 1.763 1.94 1.12 3.36 0.372 0.292 0.202 0.6939 1.45 0.819 2.57 PRS_PLINK_2.51188643150958e.06 FALSE 654.1 Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium Female 33 324 12 pregnancy complications royalblue4 324, 33 81, 10 81, 12 81, 5 81, 6 -0.187 0.143 0.191 0.7192 0.829 0.626 1.1 0.271 0.443 0.54 0.2674 1.31 0.551 3.12 -0.647 0.531 0.223 0.6519 0.524 0.185 1.48 -0.455 0.493 0.356 0.4488 0.634 0.241 1.67 PRS_PLINK_2.51188643150958e.06 TRUE 654.2 Rhesus isoimmunization in pregnancy Female 45 335 12 pregnancy complications royalblue4 335, 45 84, 10 84, 7 83, 12 84, 16 0.13 0.17 0.444 0.3523 1.14 0.816 1.59 -0.664 0.527 0.208 0.6824 0.515 0.183 1.45 0.107 0.438 0.806 0.09363 1.11 0.472 2.63 0.498 0.423 0.239 0.6221 1.65 0.719 3.77 PRS_PLINK_2.51188643150958e.06 TRUE 655 Known or suspected fetal abnormality affecting management of mother Female 402 1533 12 pregnancy complications royalblue4 1533, 402 384, 80 383, 91 383, 126 383, 105 0.122 0.0588 0.0382 1.418 1.13 1.01 1.27 0.0772 0.173 0.655 0.1835 1.08 0.77 1.52 0.492 0.163 0.00255 2.594 1.64 1.19 2.25 0.277 0.167 0.0977 1.01 1.32 0.95 1.83 PRS_PLINK_2.51188643150958e.06 FALSE 655.1 Abnormality in fetal heart rate or rhythm Female 136 791 12 pregnancy complications royalblue4 791, 136 198, 24 198, 29 197, 50 198, 33 0.0551 0.0937 0.557 0.2545 1.06 0.879 1.27 0.159 0.298 0.594 0.2263 1.17 0.654 2.1 0.773 0.27 0.00419 2.377 2.17 1.28 3.67 0.312 0.286 0.275 0.5603 1.37 0.78 2.39 PRS_PLINK_2.51188643150958e.06 FALSE 656 Other perinatal conditions of fetus or newborn Both 203 1058 12 pregnancy complications royalblue4 1058, 203 265, 54 264, 52 264, 49 265, 48 -0.0186 0.0724 0.797 0.09853 0.982 0.852 1.13 -0.13 0.216 0.548 0.2615 0.878 0.575 1.34 -0.118 0.216 0.583 0.2344 0.888 0.582 1.36 -0.102 0.216 0.636 0.1968 0.903 0.591 1.38 PRS_PLINK_2.51188643150958e.06 FALSE 656.2 Respiratory conditions of fetus and newborn Both 25 129 12 pregnancy complications royalblue4 129, 25 33, 4 32, 7 32, 5 32, 9 0.288 0.231 0.213 0.6722 1.33 0.848 2.1 0.381 0.625 0.542 0.2663 1.46 0.43 4.98 0.00793 0.672 0.991 0.00411 1.01 0.27 3.76 0.79 0.652 0.225 0.6473 2.2 0.614 7.91 PRS_PLINK_2.51188643150958e.06 TRUE 669 Complications of labor and delivery NEC Female 198 1024 12 pregnancy complications royalblue4 1024, 198 256, 46 256, 48 256, 57 256, 47 0.0547 0.0781 0.484 0.3155 1.06 0.906 1.23 0.00666 0.225 0.976 0.01036 1.01 0.647 1.57 0.221 0.217 0.31 0.5088 1.25 0.815 1.91 0.0595 0.228 0.794 0.1003 1.06 0.679 1.66 PRS_PLINK_2.51188643150958e.06 FALSE 671 Venous/cerebrovascular complications embolism in pregnancy and the puerperium Female 78 371 12 pregnancy complications royalblue4 371, 78 93, 13 93, 15 92, 22 93, 28 0.32 0.144 0.0259 1.587 1.38 1.04 1.83 0.294 0.413 0.477 0.321 1.34 0.597 3.01 0.451 0.372 0.226 0.6467 1.57 0.757 3.26 0.736 0.368 0.0454 1.343 2.09 1.02 4.3 PRS_PLINK_2.51188643150958e.06 FALSE 674 Other complications of the puerperium NEC Female 35 231 12 pregnancy complications royalblue4 231, 35 58, 6 58, 13 57, 9 58, 7 0.0272 0.178 0.878 0.05634 1.03 0.725 1.46 0.808 0.508 0.112 0.9525 2.24 0.829 6.07 0.543 0.548 0.322 0.4927 1.72 0.588 5.04 0.0896 0.556 0.872 0.05952 1.09 0.368 3.25 PRS_PLINK_2.51188643150958e.06 TRUE 676 Other disorders of the breast associated with childbirth and disorders of lactation Female 46 310 12 pregnancy complications royalblue4 310, 46 78, 8 77, 9 77, 18 78, 11 0.266 0.168 0.114 0.9436 1.3 0.938 1.81 0.345 0.517 0.505 0.2963 1.41 0.512 3.89 0.718 0.442 0.104 0.9814 2.05 0.862 4.88 0.537 0.476 0.259 0.5872 1.71 0.674 4.35 PRS_PLINK_2.51188643150958e.06 TRUE 681 Superficial cellulitis and abscess Both 2266 4700 13 dermatologic firebrick 4700, 2266 1174, 573 1175, 564 1175, 567 1175, 562 0.00773 0.0257 0.764 0.1169 1.01 0.958 1.06 -0.0146 0.0728 0.841 0.07515 0.986 0.855 1.14 -0.00312 0.0727 0.966 0.01513 0.997 0.864 1.15 -0.00195 0.0732 0.979 0.009348 0.998 0.865 1.15 PRS_PLINK_2.51188643150958e.06 FALSE 681.1 Cellulitis and abscess of fingers/toes Both 560 1670 13 dermatologic firebrick 1670, 560 418, 132 417, 151 417, 141 418, 136 -0.0164 0.0484 0.735 0.1335 0.984 0.895 1.08 0.154 0.139 0.269 0.5701 1.17 0.888 1.53 0.0685 0.141 0.626 0.2032 1.07 0.813 1.41 0.0144 0.143 0.92 0.03643 1.01 0.767 1.34 PRS_PLINK_2.51188643150958e.06 FALSE 681.2 Cellulitis and abscess of face/neck Both 312 1312 13 dermatologic firebrick 1312, 312 328, 73 328, 77 328, 75 328, 87 0.0264 0.0658 0.688 0.1624 1.03 0.902 1.17 0.0743 0.182 0.684 0.1652 1.08 0.754 1.54 -0.00416 0.183 0.982 0.007939 0.996 0.696 1.43 0.231 0.18 0.201 0.6971 1.26 0.884 1.79 PRS_PLINK_2.51188643150958e.06 FALSE 681.3 Cellulitis and abscess of arm/hand Both 889 2658 13 dermatologic firebrick 2658, 889 665, 245 664, 201 664, 215 665, 228 -0.00401 0.0389 0.918 0.03723 0.996 0.923 1.07 -0.178 0.11 0.106 0.9752 0.837 0.674 1.04 -0.137 0.109 0.21 0.6778 0.872 0.704 1.08 -0.0781 0.108 0.47 0.3275 0.925 0.748 1.14 PRS_PLINK_2.51188643150958e.06 FALSE 681.5 Cellulitis and abscess of leg, except foot Both 894 2743 13 dermatologic firebrick 2743, 894 686, 235 686, 206 685, 219 686, 234 0.0181 0.0393 0.645 0.1907 1.02 0.943 1.1 -0.108 0.11 0.327 0.486 0.897 0.723 1.11 -0.0588 0.109 0.59 0.2295 0.943 0.762 1.17 -0.00674 0.108 0.95 0.02216 0.993 0.804 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 681.6 Cellulitis and abscess of foot, toe Both 757 2262 13 dermatologic firebrick 2262, 757 566, 201 565, 169 565, 185 566, 202 0.043 0.0434 0.322 0.4922 1.04 0.959 1.14 -0.149 0.121 0.216 0.6647 0.861 0.68 1.09 -0.0649 0.119 0.585 0.2327 0.937 0.742 1.18 -0.00615 0.117 0.958 0.01855 0.994 0.79 1.25 PRS_PLINK_2.51188643150958e.06 FALSE 681.7 Cellulitis and abscess of trunk Both 583 2088 13 dermatologic firebrick 2088, 583 521, 147 522, 140 522, 142 522, 154 0.0297 0.0461 0.52 0.2842 1.03 0.941 1.13 -0.0399 0.134 0.766 0.1156 0.961 0.739 1.25 -0.0575 0.134 0.668 0.1749 0.944 0.726 1.23 0.0642 0.132 0.627 0.2027 1.07 0.823 1.38 PRS_PLINK_2.51188643150958e.06 FALSE 686 Other local infections of skin and subcutaneous tissue Both 845 2878 13 dermatologic firebrick 2878, 845 720, 214 719, 195 719, 214 720, 222 -0.000363 0.0392 0.993 0.00322 1 0.926 1.08 -0.0866 0.112 0.441 0.3558 0.917 0.736 1.14 0.0153 0.11 0.89 0.0507 1.02 0.818 1.26 0.0409 0.11 0.709 0.1491 1.04 0.84 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 686.1 Carbuncle and furuncle Both 201 780 13 dermatologic firebrick 780, 201 195, 57 195, 46 195, 44 195, 54 -0.0676 0.0777 0.384 0.4152 0.935 0.803 1.09 -0.181 0.225 0.42 0.3767 0.834 0.537 1.3 -0.267 0.228 0.241 0.6179 0.766 0.49 1.2 -0.0273 0.218 0.9 0.04557 0.973 0.635 1.49 PRS_PLINK_2.51188643150958e.06 FALSE 686.2 Impetigo Both 150 551 13 dermatologic firebrick 551, 150 138, 41 138, 34 137, 31 138, 44 0.104 0.0992 0.295 0.5295 1.11 0.913 1.35 -0.19 0.265 0.473 0.3252 0.827 0.492 1.39 -0.266 0.27 0.324 0.4895 0.766 0.452 1.3 -0.0313 0.255 0.902 0.04474 0.969 0.588 1.6 PRS_PLINK_2.51188643150958e.06 FALSE 686.3 Pilonidal cyst Both 45 187 13 dermatologic firebrick 187, 45 47, 12 47, 12 46, 15 47, 6 -0.104 0.16 0.516 0.287 0.901 0.658 1.23 0.0791 0.496 0.873 0.05889 1.08 0.41 2.86 0.243 0.447 0.587 0.2317 1.27 0.531 3.06 -0.762 0.567 0.179 0.7474 0.467 0.154 1.42 PRS_PLINK_2.51188643150958e.06 TRUE 686.4 Pyogenic granuloma Both 48 185 13 dermatologic firebrick 185, 48 47, 12 46, 12 46, 13 46, 11 -0.0144 0.138 0.917 0.03766 0.986 0.752 1.29 0.122 0.477 0.798 0.09799 1.13 0.444 2.88 0.226 0.473 0.632 0.1993 1.25 0.497 3.17 -0.125 0.476 0.793 0.1006 0.883 0.347 2.25 PRS_PLINK_2.51188643150958e.06 TRUE 686.5 Pyoderma Both 27 90 13 dermatologic firebrick 90, 27 23, 10 22, 11 22, 2 23, 4 -0.13 0.253 0.606 0.2173 0.878 0.535 1.44 0.0622 0.544 0.909 0.0415 1.06 0.367 3.09 -1.58 0.844 0.0621 1.207 0.207 0.0395 1.08 -0.636 0.693 0.359 0.4452 0.529 0.136 2.06 PRS_PLINK_2.51188643150958e.06 TRUE 687 Symptoms affecting skin Both 708 1747 13 dermatologic firebrick 1747, 708 437, 154 437, 181 436, 204 437, 169 0.0809 0.0474 0.0881 1.055 1.08 0.988 1.19 0.18 0.13 0.165 0.7826 1.2 0.929 1.54 0.274 0.128 0.032 1.495 1.32 1.02 1.69 0.0876 0.131 0.504 0.2972 1.09 0.844 1.41 PRS_PLINK_2.51188643150958e.06 FALSE 687.1 Rash and other nonspecific skin eruption Both 2645 3241 13 dermatologic firebrick 3241, 2645 811, 642 810, 661 810, 678 810, 664 0.0383 0.0267 0.151 0.8197 1.04 0.986 1.09 0.028 0.0758 0.712 0.1475 1.03 0.886 1.19 0.0452 0.0754 0.549 0.2604 1.05 0.902 1.21 0.0486 0.0756 0.52 0.2838 1.05 0.905 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 687.3 Changes in skin texture Both 175 492 13 dermatologic firebrick 492, 175 123, 45 123, 44 123, 45 123, 41 0.00489 0.088 0.956 0.01968 1 0.846 1.19 -0.00117 0.253 0.996 0.001609 0.999 0.609 1.64 -0.0193 0.249 0.938 0.02768 0.981 0.602 1.6 -0.0951 0.257 0.712 0.1477 0.909 0.549 1.51 PRS_PLINK_2.51188643150958e.06 FALSE 687.4 Disturbance of skin sensation Both 2490 3227 13 dermatologic firebrick 3227, 2490 807, 625 807, 634 806, 622 807, 608 0.00445 0.0266 0.867 0.06195 1 0.953 1.06 0.0159 0.0761 0.835 0.07847 1.02 0.875 1.18 -0.000951 0.0762 0.99 0.004347 0.999 0.86 1.16 -0.0177 0.0767 0.817 0.08759 0.982 0.845 1.14 PRS_PLINK_2.51188643150958e.06 FALSE 689 Disorder of skin and subcutaneous tissue NOS Both 2959 4486 13 dermatologic firebrick 4486, 2959 1121, 744 1121, 696 1121, 726 1122, 793 0.0414 0.0244 0.0907 1.042 1.04 0.993 1.09 -0.0895 0.0694 0.197 0.7047 0.914 0.798 1.05 -0.0283 0.0688 0.682 0.1665 0.972 0.849 1.11 0.0809 0.0682 0.235 0.6281 1.08 0.949 1.24 PRS_PLINK_2.51188643150958e.06 FALSE 690 Erythematosquamous dermatosis Both 1778 3886 13 dermatologic firebrick 3886, 1778 971, 446 971, 413 971, 429 972, 490 0.0407 0.0296 0.169 0.7713 1.04 0.983 1.1 -0.0712 0.085 0.402 0.3956 0.931 0.788 1.1 -0.0378 0.084 0.653 0.1853 0.963 0.817 1.14 0.116 0.0819 0.159 0.7995 1.12 0.956 1.32 PRS_PLINK_2.51188643150958e.06 FALSE 690.1 Seborrheic dermatitis Both 1776 3885 13 dermatologic firebrick 3885, 1776 971, 445 971, 413 971, 429 971, 489 0.0406 0.0296 0.17 0.7684 1.04 0.983 1.1 -0.0677 0.085 0.426 0.3708 0.935 0.791 1.1 -0.0335 0.084 0.69 0.1612 0.967 0.82 1.14 0.118 0.082 0.149 0.8268 1.13 0.958 1.32 PRS_PLINK_2.51188643150958e.06 FALSE 691 Congenital anomalies of skin Both 186 670 13 dermatologic firebrick 670, 186 168, 42 167, 57 167, 33 168, 54 0.0521 0.0869 0.549 0.2602 1.05 0.888 1.25 0.338 0.236 0.152 0.8179 1.4 0.883 2.22 -0.208 0.26 0.424 0.373 0.812 0.489 1.35 0.203 0.234 0.386 0.413 1.22 0.774 1.94 PRS_PLINK_2.51188643150958e.06 FALSE 691.3 Congenital pigmentary anomalies of skin Both 28 77 13 dermatologic firebrick 77, 28 20, 10 19, 7 19, 5 19, 6 -0.185 0.305 0.544 0.2648 0.831 0.457 1.51 -0.31 0.716 0.665 0.1769 0.734 0.18 2.99 -0.48 0.706 0.497 0.304 0.619 0.155 2.47 -0.32 0.683 0.639 0.1942 0.726 0.191 2.77 PRS_PLINK_2.51188643150958e.06 TRUE 694 Dyschromia and Vitiligo Both 617 2301 13 dermatologic firebrick 2301, 617 575, 134 575, 164 575, 160 575, 159 0.0525 0.046 0.253 0.5962 1.05 0.963 1.15 0.205 0.131 0.118 0.927 1.23 0.949 1.59 0.176 0.131 0.179 0.7469 1.19 0.923 1.54 0.162 0.132 0.219 0.6597 1.18 0.908 1.52 PRS_PLINK_2.51188643150958e.06 FALSE 694.1 Vitiligo Both 47 183 13 dermatologic firebrick 183, 47 46, 16 46, 11 45, 11 46, 9 -0.191 0.145 0.188 0.7255 0.826 0.621 1.1 -0.523 0.479 0.275 0.5614 0.593 0.232 1.51 -0.267 0.45 0.553 0.2569 0.766 0.317 1.85 -0.753 0.496 0.129 0.8899 0.471 0.178 1.24 PRS_PLINK_2.51188643150958e.06 TRUE 694.2 Other dyschromia Both 541 2110 13 dermatologic firebrick 2110, 541 527, 109 527, 146 527, 140 528, 146 0.11 0.0511 0.032 1.495 1.12 1.01 1.23 0.288 0.142 0.0424 1.373 1.33 1.01 1.76 0.248 0.142 0.08 1.097 1.28 0.971 1.69 0.28 0.141 0.047 1.328 1.32 1 1.75 PRS_PLINK_2.51188643150958e.06 FALSE 694.3 Vascular disorders of skin Both 44 100 13 dermatologic firebrick 100, 44 25, 14 25, 12 25, 9 25, 9 -0.282 0.167 0.0911 1.041 0.754 0.544 1.05 -0.377 0.532 0.479 0.3197 0.686 0.242 1.95 -0.523 0.54 0.333 0.478 0.593 0.206 1.71 -0.427 0.563 0.448 0.3492 0.652 0.216 1.97 PRS_PLINK_2.51188643150958e.06 TRUE 695 Erythematous conditions Both 1499 3775 13 dermatologic firebrick 3775, 1499 943, 357 944, 364 943, 374 944, 404 0.0393 0.031 0.205 0.6892 1.04 0.979 1.11 0.0119 0.0887 0.893 0.04891 1.01 0.851 1.2 0.0357 0.0881 0.686 0.164 1.04 0.872 1.23 0.123 0.087 0.157 0.8049 1.13 0.954 1.34 PRS_PLINK_2.51188643150958e.06 FALSE 695.1 Toxic erythema Both 26 84 13 dermatologic firebrick 84, 26 21, 9 21, 7 21, 6 21, 4 -0.0876 0.21 0.677 0.1696 0.916 0.607 1.38 -0.35 0.658 0.595 0.2253 0.705 0.194 2.56 -0.147 0.665 0.825 0.08338 0.864 0.235 3.18 -0.96 0.776 0.216 0.6649 0.383 0.0837 1.75 PRS_PLINK_2.51188643150958e.06 TRUE 695.2 Bullous dermatoses Both 33 104 13 dermatologic firebrick 104, 33 26, 5 26, 7 26, 11 26, 10 -0.12 0.19 0.527 0.2786 0.887 0.612 1.29 0.349 0.666 0.601 0.2214 1.42 0.384 5.23 0.533 0.694 0.442 0.3545 1.7 0.438 6.64 0.377 0.636 0.553 0.2569 1.46 0.419 5.07 PRS_PLINK_2.51188643150958e.06 TRUE 695.3 Rosacea Both 628 2337 13 dermatologic firebrick 2337, 628 584, 161 584, 134 584, 153 584, 180 0.0516 0.0454 0.256 0.5925 1.05 0.963 1.15 -0.151 0.132 0.251 0.6 0.86 0.664 1.11 -0.0408 0.128 0.749 0.1253 0.96 0.747 1.23 0.121 0.124 0.33 0.4812 1.13 0.885 1.44 PRS_PLINK_2.51188643150958e.06 FALSE 695.4 Lupus (localized and systemic) Both 285 796 13 dermatologic firebrick 796, 285 199, 68 199, 69 199, 73 199, 75 0.0932 0.0696 0.181 0.7424 1.1 0.958 1.26 0.043 0.2 0.83 0.08111 1.04 0.706 1.54 0.087 0.198 0.66 0.1803 1.09 0.74 1.61 0.0975 0.197 0.621 0.2068 1.1 0.749 1.62 PRS_PLINK_2.51188643150958e.06 FALSE 695.41 Cutaneous lupus erythematosus Both 103 286 13 dermatologic firebrick 286, 103 72, 17 71, 27 71, 31 72, 28 0.213 0.126 0.0916 1.038 1.24 0.966 1.58 0.52 0.359 0.147 0.832 1.68 0.833 3.4 0.588 0.347 0.0899 1.046 1.8 0.913 3.55 0.693 0.366 0.0583 1.234 2 0.976 4.1 PRS_PLINK_2.51188643150958e.06 FALSE 695.42 Systemic lupus erythematosus Both 272 751 13 dermatologic firebrick 751, 272 188, 62 188, 69 187, 70 188, 71 0.0907 0.0693 0.191 0.7197 1.09 0.956 1.25 0.157 0.206 0.444 0.3528 1.17 0.782 1.75 0.144 0.204 0.482 0.3172 1.15 0.773 1.72 0.137 0.204 0.504 0.2975 1.15 0.768 1.71 PRS_PLINK_2.51188643150958e.06 FALSE 695.7 Prurigo and Lichen Both 213 784 13 dermatologic firebrick 784, 213 196, 43 196, 65 196, 53 196, 52 0.0148 0.077 0.847 0.07186 1.01 0.873 1.18 0.364 0.226 0.108 0.9672 1.44 0.923 2.24 0.202 0.233 0.386 0.4135 1.22 0.775 1.93 0.154 0.238 0.516 0.2872 1.17 0.732 1.86 PRS_PLINK_2.51188643150958e.06 FALSE 695.8 Other specified erythematous conditions Both 365 1078 13 dermatologic firebrick 1078, 365 270, 77 269, 99 269, 110 270, 79 0.0569 0.0628 0.364 0.4385 1.06 0.936 1.2 0.252 0.176 0.153 0.8147 1.29 0.911 1.82 0.329 0.173 0.0574 1.241 1.39 0.99 1.95 0.0382 0.183 0.835 0.07851 1.04 0.726 1.49 PRS_PLINK_2.51188643150958e.06 FALSE 695.81 Erythema nodosum Both 29 56 13 dermatologic firebrick 56, 29 14, 5 14, 7 14, 8 14, 9 0.144 0.288 0.618 0.2091 1.15 0.657 2.03 -0.182 0.776 0.815 0.08887 0.834 0.182 3.81 0.6 0.896 0.503 0.2981 1.82 0.314 10.6 0.342 0.738 0.643 0.1919 1.41 0.331 5.99 PRS_PLINK_2.51188643150958e.06 TRUE 695.9 Unspecified erythematous condition Both 256 928 13 dermatologic firebrick 928, 256 232, 61 232, 62 232, 59 232, 74 0.0965 0.0739 0.192 0.7174 1.1 0.953 1.27 0.0106 0.203 0.958 0.01842 1.01 0.678 1.51 -0.0516 0.206 0.802 0.0956 0.95 0.634 1.42 0.173 0.196 0.379 0.4217 1.19 0.809 1.75 PRS_PLINK_2.51188643150958e.06 FALSE 696 Psoriasis and related disorders Both 459 1676 13 dermatologic firebrick 1676, 459 419, 100 419, 107 419, 127 419, 125 0.104 0.0554 0.0614 1.212 1.11 0.995 1.24 0.101 0.157 0.522 0.282 1.11 0.813 1.5 0.259 0.151 0.0861 1.065 1.3 0.964 1.74 0.245 0.152 0.107 0.969 1.28 0.948 1.72 PRS_PLINK_2.51188643150958e.06 FALSE 696.3 Pityriasis Both 21 116 13 dermatologic firebrick 116, 21 29, 6 29, 3 29, 7 29, 5 -0.0346 0.259 0.894 0.04874 0.966 0.581 1.61 -0.525 0.724 0.469 0.3293 0.592 0.143 2.45 0.179 0.621 0.773 0.1117 1.2 0.354 4.04 -0.474 0.651 0.466 0.3313 0.622 0.174 2.23 PRS_PLINK_2.51188643150958e.06 TRUE 696.4 Psoriasis Both 440 1597 13 dermatologic firebrick 1597, 440 400, 90 399, 109 399, 121 399, 120 0.0978 0.0562 0.0818 1.087 1.1 0.988 1.23 0.231 0.161 0.151 0.8205 1.26 0.919 1.73 0.308 0.156 0.0489 1.311 1.36 1 1.85 0.306 0.157 0.0519 1.285 1.36 0.998 1.85 PRS_PLINK_2.51188643150958e.06 FALSE 696.41 Psoriasis vulgaris Both 407 1460 13 dermatologic firebrick 1460, 407 365, 89 365, 96 365, 114 365, 108 0.0823 0.057 0.149 0.8283 1.09 0.971 1.21 0.111 0.167 0.507 0.2951 1.12 0.805 1.55 0.247 0.16 0.122 0.9145 1.28 0.936 1.75 0.216 0.162 0.183 0.7375 1.24 0.903 1.71 PRS_PLINK_2.51188643150958e.06 FALSE 696.42 Psoriatic arthropathy Both 98 360 13 dermatologic firebrick 360, 98 90, 17 90, 28 90, 28 90, 25 0.139 0.117 0.233 0.6328 1.15 0.914 1.44 0.597 0.361 0.0981 1.008 1.82 0.896 3.68 0.46 0.348 0.186 0.7299 1.58 0.801 3.13 0.42 0.356 0.238 0.6226 1.52 0.757 3.06 PRS_PLINK_2.51188643150958e.06 FALSE 697 Sarcoidosis Both 109 411 13 dermatologic firebrick 411, 109 103, 32 103, 19 102, 28 103, 30 -0.0587 0.0972 0.546 0.2631 0.943 0.779 1.14 -0.554 0.327 0.0897 1.047 0.575 0.303 1.09 -0.102 0.295 0.728 0.1378 0.903 0.507 1.61 -0.00215 0.298 0.994 0.00251 0.998 0.556 1.79 PRS_PLINK_2.51188643150958e.06 FALSE 698 Pruritus and related conditions Both 894 3530 13 dermatologic firebrick 3530, 894 883, 212 882, 241 882, 232 883, 209 0.0302 0.0384 0.431 0.3655 1.03 0.956 1.11 0.129 0.106 0.223 0.6515 1.14 0.925 1.4 0.0953 0.107 0.374 0.4277 1.1 0.892 1.36 -0.0219 0.109 0.841 0.07527 0.978 0.79 1.21 PRS_PLINK_2.51188643150958e.06 FALSE 700 Corns and callosities Both 630 1608 13 dermatologic firebrick 1608, 630 401, 159 402, 133 402, 181 402, 157 0.0458 0.0478 0.338 0.4709 1.05 0.953 1.15 -0.175 0.138 0.207 0.6846 0.84 0.64 1.1 0.134 0.131 0.309 0.5106 1.14 0.884 1.48 -0.0222 0.134 0.868 0.06123 0.978 0.752 1.27 PRS_PLINK_2.51188643150958e.06 FALSE 701 Other hypertrophic and atrophic conditions of skin Both 2294 4804 13 dermatologic firebrick 4804, 2294 1200, 554 1201, 542 1201, 597 1201, 601 0.0527 0.026 0.0424 1.372 1.05 1 1.11 -0.033 0.0741 0.656 0.183 0.968 0.837 1.12 0.0768 0.0731 0.293 0.533 1.08 0.936 1.25 0.0996 0.0728 0.171 0.766 1.1 0.958 1.27 PRS_PLINK_2.51188643150958e.06 FALSE 701.1 Keratoderma, acquired Both 223 809 13 dermatologic firebrick 809, 223 203, 51 202, 52 202, 63 202, 57 0.132 0.0818 0.106 0.9745 1.14 0.972 1.34 0.0817 0.224 0.715 0.1456 1.09 0.7 1.68 0.246 0.221 0.265 0.5772 1.28 0.83 1.97 0.153 0.222 0.491 0.3085 1.16 0.754 1.8 PRS_PLINK_2.51188643150958e.06 FALSE 701.2 Scar conditions and fibrosis of skin Both 472 2873 13 dermatologic firebrick 2873, 472 719, 108 718, 110 718, 131 718, 123 0.1 0.0525 0.0562 1.251 1.11 0.997 1.23 0.015 0.145 0.917 0.03746 1.02 0.764 1.35 0.189 0.14 0.177 0.7523 1.21 0.918 1.59 0.148 0.143 0.301 0.5209 1.16 0.876 1.53 PRS_PLINK_2.51188643150958e.06 FALSE 701.3 Circumscribed scleroderma Both 172 841 13 dermatologic firebrick 841, 172 211, 48 210, 36 210, 43 210, 45 0.0722 0.0905 0.425 0.3718 1.07 0.9 1.28 -0.191 0.244 0.434 0.3625 0.826 0.513 1.33 -0.0481 0.233 0.836 0.07757 0.953 0.604 1.5 0.000986 0.232 0.997 0.001478 1 0.636 1.58 PRS_PLINK_2.51188643150958e.06 FALSE 701.4 Keloid scar Both 134 765 13 dermatologic firebrick 765, 134 192, 28 191, 27 191, 45 191, 34 0.0236 0.0886 0.79 0.1021 1.02 0.861 1.22 -0.0483 0.289 0.868 0.06171 0.953 0.54 1.68 0.474 0.262 0.0708 1.15 1.61 0.961 2.68 0.175 0.272 0.522 0.2826 1.19 0.698 2.03 PRS_PLINK_2.51188643150958e.06 FALSE 701.5 Abnormal granulation tissue Both 123 545 13 dermatologic firebrick 545, 123 137, 25 136, 31 136, 30 136, 37 0.114 0.0973 0.242 0.617 1.12 0.926 1.36 0.266 0.295 0.367 0.4356 1.3 0.732 2.32 0.241 0.297 0.418 0.3793 1.27 0.711 2.28 0.434 0.285 0.127 0.8949 1.54 0.883 2.7 PRS_PLINK_2.51188643150958e.06 FALSE 702 Degenerative skin conditions and other dermatoses Both 2319 3429 13 dermatologic firebrick 3429, 2319 857, 610 857, 545 857, 541 857, 623 0.0278 0.0283 0.325 0.4886 1.03 0.973 1.09 -0.126 0.081 0.119 0.9246 0.881 0.752 1.03 -0.125 0.0813 0.123 0.9084 0.882 0.752 1.03 0.0318 0.0791 0.688 0.1626 1.03 0.884 1.21 PRS_PLINK_2.51188643150958e.06 FALSE 702.1 Actinic keratosis Both 1424 3616 13 dermatologic firebrick 3616, 1424 903, 384 904, 316 904, 341 904, 383 0.0252 0.033 0.446 0.3509 1.03 0.961 1.09 -0.164 0.0936 0.0794 1.1 0.849 0.706 1.02 -0.112 0.0926 0.227 0.6436 0.894 0.746 1.07 0.0309 0.0908 0.734 0.1346 1.03 0.863 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 702.2 Seborrheic keratosis Both 1891 4333 13 dermatologic firebrick 4333, 1891 1083, 486 1083, 466 1083, 435 1083, 504 0.0122 0.0289 0.674 0.1714 1.01 0.957 1.07 -0.0802 0.0817 0.326 0.4863 0.923 0.786 1.08 -0.128 0.0825 0.122 0.9126 0.88 0.749 1.03 0.052 0.0802 0.517 0.2866 1.05 0.9 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 702.4 Degenerative skin disorders Both 35 116 13 dermatologic firebrick 116, 35 29, 13 29, 6 29, 11 29, 5 -0.154 0.199 0.438 0.3584 0.857 0.581 1.27 -0.533 0.597 0.372 0.4294 0.587 0.182 1.89 -0.06 0.527 0.909 0.04128 0.942 0.335 2.64 -0.718 0.612 0.241 0.6181 0.488 0.147 1.62 PRS_PLINK_2.51188643150958e.06 TRUE 703 Diseases of nail, NOS Both 726 2318 13 dermatologic firebrick 2318, 726 580, 197 579, 164 579, 190 580, 175 -0.0338 0.0415 0.415 0.3815 0.967 0.891 1.05 -0.174 0.122 0.153 0.8156 0.841 0.662 1.07 -0.0319 0.119 0.788 0.1035 0.969 0.768 1.22 -0.129 0.121 0.285 0.5457 0.879 0.694 1.11 PRS_PLINK_2.51188643150958e.06 FALSE 703.1 Ingrowing nail Both 390 1363 13 dermatologic firebrick 1363, 390 340, 103 341, 84 340, 103 341, 100 -0.00271 0.0546 0.96 0.01756 0.997 0.896 1.11 -0.193 0.167 0.249 0.6046 0.825 0.595 1.14 -0.0182 0.161 0.91 0.04112 0.982 0.716 1.35 -0.0242 0.162 0.881 0.05486 0.976 0.711 1.34 PRS_PLINK_2.51188643150958e.06 FALSE 704 Diseases of hair and hair follicles Both 1078 4209 13 dermatologic firebrick 4209, 1078 1052, 244 1052, 249 1052, 280 1052, 305 0.0942 0.0357 0.0084 2.076 1.1 1.02 1.18 0.0191 0.101 0.849 0.07095 1.02 0.837 1.24 0.146 0.098 0.135 0.8695 1.16 0.955 1.4 0.233 0.0968 0.016 1.796 1.26 1.04 1.53 PRS_PLINK_2.51188643150958e.06 FALSE 704.1 Alopecia Both 519 2041 13 dermatologic firebrick 2041, 519 511, 118 510, 130 510, 142 510, 129 0.0266 0.0506 0.599 0.2223 1.03 0.93 1.13 0.0885 0.143 0.535 0.2715 1.09 0.826 1.45 0.205 0.14 0.144 0.8404 1.23 0.932 1.62 0.0892 0.142 0.531 0.2746 1.09 0.827 1.45 PRS_PLINK_2.51188643150958e.06 FALSE 704.11 Alopecia Areata Both 31 139 13 dermatologic firebrick 139, 31 35, 5 35, 11 34, 6 35, 9 0.119 0.206 0.562 0.2503 1.13 0.753 1.69 0.601 0.579 0.299 0.5244 1.82 0.587 5.67 0.174 0.64 0.785 0.105 1.19 0.34 4.17 -0.0637 0.632 0.92 0.03634 0.938 0.272 3.24 PRS_PLINK_2.51188643150958e.06 TRUE 704.12 Telogen effluvium Both 26 92 13 dermatologic firebrick 92, 26 23, 1 23, 5 23, 8 23, 12 0.541 0.267 0.043 1.366 1.72 1.02 2.9 1.35 0.937 0.15 0.8245 3.85 0.615 24.2 1.67 0.883 0.0578 1.238 5.34 0.946 30.1 1.94 0.876 0.0268 1.571 6.96 1.25 38.7 PRS_PLINK_2.51188643150958e.06 TRUE 704.2 Hirsutism Both 98 419 13 dermatologic firebrick 419, 98 105, 19 105, 27 104, 24 105, 28 0.187 0.12 0.119 0.9241 1.21 0.953 1.52 0.31 0.331 0.349 0.4566 1.36 0.712 2.61 0.295 0.336 0.381 0.4195 1.34 0.695 2.6 0.429 0.325 0.186 0.7304 1.54 0.813 2.9 PRS_PLINK_2.51188643150958e.06 FALSE 704.8 Other specified diseases of hair and hair follicles Both 596 2509 13 dermatologic firebrick 2509, 596 627, 127 627, 130 627, 165 627, 174 0.126 0.0483 0.00917 2.038 1.13 1.03 1.25 0.014 0.137 0.919 0.03682 1.01 0.775 1.33 0.254 0.131 0.0517 1.286 1.29 0.998 1.67 0.31 0.13 0.0173 1.762 1.36 1.06 1.76 PRS_PLINK_2.51188643150958e.06 FALSE 705 Disorders of sweat glands Both 190 824 13 dermatologic firebrick 824, 190 206, 47 206, 55 206, 49 206, 39 -0.0391 0.0767 0.61 0.2146 0.962 0.827 1.12 0.144 0.225 0.524 0.2808 1.15 0.742 1.8 -0.0213 0.233 0.927 0.03278 0.979 0.62 1.55 -0.18 0.238 0.448 0.3484 0.835 0.524 1.33 PRS_PLINK_2.51188643150958e.06 FALSE 705.1 Dyshidrosis Both 56 236 13 dermatologic firebrick 236, 56 59, 13 59, 14 59, 17 59, 12 -0.0915 0.147 0.533 0.2735 0.913 0.685 1.22 -0.0274 0.427 0.949 0.02275 0.973 0.421 2.25 0.302 0.431 0.483 0.3156 1.35 0.581 3.15 -0.061 0.432 0.888 0.05175 0.941 0.404 2.19 PRS_PLINK_2.51188643150958e.06 FALSE 705.3 Hidradenitis Both 71 344 13 dermatologic firebrick 344, 71 86, 25 86, 16 86, 17 86, 13 -0.223 0.124 0.0719 1.143 0.8 0.628 1.02 -0.454 0.365 0.213 0.6708 0.635 0.311 1.3 -0.385 0.357 0.28 0.5528 0.68 0.338 1.37 -0.693 0.378 0.067 1.174 0.5 0.238 1.05 PRS_PLINK_2.51188643150958e.06 FALSE 705.8 Hyperhidrosis Both 449 1536 13 dermatologic firebrick 1536, 449 384, 106 384, 127 384, 102 384, 114 0.0113 0.0524 0.829 0.08154 1.01 0.913 1.12 0.181 0.151 0.232 0.6352 1.2 0.891 1.61 -0.005 0.158 0.975 0.0111 0.995 0.73 1.36 0.0552 0.155 0.722 0.1413 1.06 0.78 1.43 PRS_PLINK_2.51188643150958e.06 FALSE 706 Diseases of sebaceous glands Both 1972 5135 13 dermatologic firebrick 5135, 1972 1283, 467 1284, 497 1283, 477 1284, 531 0.0589 0.0273 0.0309 1.51 1.06 1.01 1.12 0.0641 0.0765 0.402 0.3955 1.07 0.918 1.24 0.0428 0.077 0.579 0.2376 1.04 0.897 1.21 0.159 0.0757 0.0354 1.451 1.17 1.01 1.36 PRS_PLINK_2.51188643150958e.06 FALSE 706.1 Acne Both 766 2934 13 dermatologic firebrick 2934, 766 733, 174 733, 203 733, 180 734, 209 0.072 0.0409 0.0784 1.105 1.07 0.992 1.16 0.151 0.116 0.195 0.7102 1.16 0.926 1.46 0.0363 0.119 0.76 0.1192 1.04 0.822 1.31 0.191 0.115 0.0975 1.011 1.21 0.966 1.52 PRS_PLINK_2.51188643150958e.06 FALSE 706.2 Sebaceous cyst Both 929 3702 13 dermatologic firebrick 3702, 929 925, 224 925, 236 925, 221 926, 248 0.0481 0.0363 0.186 0.7311 1.05 0.977 1.13 0.0462 0.105 0.659 0.181 1.05 0.853 1.29 0.000687 0.106 0.995 0.00225 1 0.813 1.23 0.119 0.104 0.252 0.5991 1.13 0.919 1.38 PRS_PLINK_2.51188643150958e.06 FALSE 706.3 Seborrhea Both 30 92 13 dermatologic firebrick 92, 30 23, 12 23, 7 23, 5 23, 6 0.00302 0.222 0.989 0.004728 1 0.649 1.55 -0.376 0.598 0.53 0.2761 0.687 0.213 2.22 -0.868 0.624 0.164 0.7853 0.42 0.124 1.43 -0.467 0.581 0.422 0.3745 0.627 0.201 1.96 PRS_PLINK_2.51188643150958e.06 TRUE 706.8 Other specified diseases of sebaceous glands Both 721 2323 13 dermatologic firebrick 2323, 721 580, 168 581, 178 580, 196 581, 179 0.0236 0.0419 0.574 0.2411 1.02 0.943 1.11 0.0488 0.123 0.693 0.1595 1.05 0.824 1.34 0.15 0.121 0.212 0.6732 1.16 0.918 1.47 0.0633 0.123 0.608 0.2163 1.07 0.837 1.36 PRS_PLINK_2.51188643150958e.06 FALSE 707 Chronic ulcer of skin Both 1122 4217 13 dermatologic firebrick 4217, 1122 1054, 308 1054, 234 1054, 280 1054, 300 -0.00499 0.0338 0.883 0.05421 0.995 0.931 1.06 -0.27 0.0975 0.00553 2.257 0.763 0.63 0.924 -0.0932 0.0938 0.32 0.4947 0.911 0.758 1.09 -0.0345 0.0928 0.71 0.1485 0.966 0.805 1.16 PRS_PLINK_2.51188643150958e.06 FALSE 707.1 Decubitus ulcer Both 381 1335 13 dermatologic firebrick 1335, 381 334, 95 334, 81 333, 98 334, 107 0.0675 0.0591 0.253 0.596 1.07 0.953 1.2 -0.156 0.171 0.362 0.4412 0.856 0.613 1.2 0.0537 0.165 0.745 0.1279 1.06 0.763 1.46 0.1 0.163 0.537 0.2699 1.11 0.804 1.52 PRS_PLINK_2.51188643150958e.06 FALSE 707.2 Chronic ulcer of leg or foot Both 496 1694 13 dermatologic firebrick 1694, 496 424, 132 423, 112 423, 120 424, 132 0.0173 0.0511 0.735 0.1335 1.02 0.921 1.12 -0.146 0.147 0.318 0.4971 0.864 0.648 1.15 -0.101 0.145 0.486 0.3133 0.904 0.681 1.2 -0.006 0.143 0.966 0.01482 0.994 0.752 1.31 PRS_PLINK_2.51188643150958e.06 FALSE 707.3 Chronic ulcer of unspecified site Both 621 2635 13 dermatologic firebrick 2635, 621 659, 178 659, 119 658, 159 659, 165 -0.0301 0.0444 0.498 0.3025 0.97 0.889 1.06 -0.389 0.131 0.003 2.522 0.678 0.525 0.876 -0.103 0.123 0.401 0.3965 0.902 0.709 1.15 -0.0808 0.123 0.511 0.2919 0.922 0.725 1.17 PRS_PLINK_2.51188643150958e.06 FALSE 709 Diffuse diseases of connective tissue Both 661 1797 13 dermatologic firebrick 1797, 661 449, 161 449, 145 449, 165 449, 190 0.0718 0.0474 0.13 0.8866 1.07 0.979 1.18 -0.118 0.134 0.376 0.4244 0.888 0.683 1.15 0.0247 0.13 0.849 0.07103 1.03 0.794 1.32 0.182 0.128 0.154 0.8116 1.2 0.934 1.54 PRS_PLINK_2.51188643150958e.06 FALSE 709.2 Sicca syndrome Both 221 578 13 dermatologic firebrick 578, 221 145, 55 144, 53 144, 58 145, 55 0.0377 0.0832 0.65 0.1869 1.04 0.882 1.22 -0.0333 0.23 0.885 0.05309 0.967 0.616 1.52 0.0788 0.223 0.724 0.1403 1.08 0.699 1.68 0.00975 0.227 0.966 0.01516 1.01 0.648 1.57 PRS_PLINK_2.51188643150958e.06 FALSE 709.3 Systemic sclerosis Both 117 257 13 dermatologic firebrick 257, 117 65, 27 64, 29 64, 30 64, 31 0.0511 0.115 0.657 0.1825 1.05 0.84 1.32 0.0214 0.335 0.949 0.02276 1.02 0.53 1.97 0.114 0.325 0.727 0.1385 1.12 0.592 2.12 0.255 0.341 0.454 0.343 1.29 0.662 2.52 PRS_PLINK_2.51188643150958e.06 FALSE 709.5 Dermatomyositis Both 38 124 13 dermatologic firebrick 124, 38 31, 12 31, 7 31, 13 31, 6 -0.288 0.236 0.224 0.6503 0.75 0.472 1.19 -0.609 0.567 0.282 0.5494 0.544 0.179 1.65 -0.0509 0.544 0.925 0.03363 0.95 0.327 2.76 -1.03 0.645 0.111 0.9543 0.358 0.101 1.27 PRS_PLINK_2.51188643150958e.06 TRUE 709.6 Other specified diffuse diseases of connective tissue Both 43 106 13 dermatologic firebrick 106, 43 27, 9 26, 9 26, 14 27, 11 0.243 0.206 0.238 0.6227 1.28 0.851 1.91 -0.0178 0.591 0.976 0.01054 0.982 0.308 3.13 0.577 0.534 0.279 0.5539 1.78 0.626 5.07 -0.256 0.571 0.653 0.1848 0.774 0.253 2.37 PRS_PLINK_2.51188643150958e.06 TRUE 709.7 Unspecified diffuse connective tissue disease Both 441 1170 13 dermatologic firebrick 1170, 441 293, 114 292, 91 292, 112 293, 124 0.0339 0.0575 0.555 0.2557 1.03 0.924 1.16 -0.24 0.165 0.148 0.831 0.787 0.569 1.09 -0.0115 0.157 0.942 0.02611 0.989 0.726 1.35 0.0979 0.157 0.532 0.2742 1.1 0.811 1.5 PRS_PLINK_2.51188643150958e.06 FALSE 710 Osteomyelitis, periostitis, and other infections involving bone Both 416 1426 14 musculoskeletal darkolivegreen 1426, 416 357, 110 356, 114 356, 96 357, 96 -0.00781 0.0545 0.886 0.05259 0.992 0.892 1.1 0.0419 0.154 0.786 0.1046 1.04 0.771 1.41 -0.132 0.16 0.41 0.3871 0.877 0.641 1.2 -0.108 0.161 0.502 0.2994 0.898 0.655 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 710.1 Osteomyelitis Both 404 1363 14 musculoskeletal darkolivegreen 1363, 404 341, 108 341, 112 340, 92 341, 92 -0.0199 0.0557 0.72 0.1424 0.98 0.879 1.09 0.0491 0.157 0.754 0.1229 1.05 0.773 1.43 -0.155 0.163 0.341 0.4674 0.856 0.623 1.18 -0.133 0.164 0.417 0.3798 0.875 0.635 1.21 PRS_PLINK_2.51188643150958e.06 FALSE 710.11 Acute osteomyelitis Both 226 676 14 musculoskeletal darkolivegreen 676, 226 169, 48 169, 69 169, 57 169, 52 0.0214 0.0774 0.782 0.1069 1.02 0.878 1.19 0.421 0.224 0.0598 1.224 1.52 0.983 2.36 0.168 0.228 0.46 0.3372 1.18 0.757 1.85 0.182 0.233 0.435 0.3614 1.2 0.759 1.9 PRS_PLINK_2.51188643150958e.06 FALSE 710.12 Chronic osteomyelitis Both 187 628 14 musculoskeletal darkolivegreen 628, 187 157, 45 157, 52 157, 37 157, 53 -0.00197 0.0799 0.98 0.008645 0.998 0.853 1.17 0.202 0.239 0.398 0.4 1.22 0.766 1.96 -0.11 0.253 0.663 0.1782 0.896 0.546 1.47 0.239 0.238 0.315 0.5016 1.27 0.797 2.02 PRS_PLINK_2.51188643150958e.06 FALSE 710.19 Unspecified osteomyelitis Both 387 1309 14 musculoskeletal darkolivegreen 1309, 387 328, 102 327, 108 327, 89 327, 88 -0.0111 0.0564 0.843 0.07403 0.989 0.885 1.1 0.0559 0.16 0.726 0.1388 1.06 0.773 1.45 -0.129 0.166 0.438 0.3587 0.879 0.635 1.22 -0.131 0.168 0.436 0.3602 0.878 0.632 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 711 Arthropathy associated with infections Both 135 480 14 musculoskeletal darkolivegreen 480, 135 120, 34 120, 37 120, 35 120, 29 -0.059 0.0956 0.537 0.2698 0.943 0.782 1.14 0.0977 0.275 0.722 0.1413 1.1 0.644 1.89 -0.000457 0.276 0.999 0.000574 1 0.582 1.72 -0.0618 0.295 0.834 0.07875 0.94 0.527 1.68 PRS_PLINK_2.51188643150958e.06 FALSE 711.1 Pyogenic arthritis Both 84 343 14 musculoskeletal darkolivegreen 343, 84 86, 19 86, 23 85, 21 86, 21 0.0383 0.123 0.757 0.1211 1.04 0.816 1.32 0.225 0.353 0.523 0.2813 1.25 0.627 2.5 0.175 0.367 0.633 0.1983 1.19 0.58 2.44 0.215 0.368 0.559 0.2526 1.24 0.603 2.55 PRS_PLINK_2.51188643150958e.06 FALSE 712 Infective connective tissue disorders Both 82 197 14 musculoskeletal darkolivegreen 197, 82 50, 17 49, 17 49, 23 49, 25 0.135 0.138 0.326 0.4862 1.14 0.874 1.5 0.00187 0.401 0.996 0.001616 1 0.456 2.2 0.306 0.393 0.437 0.3599 1.36 0.628 2.94 0.491 0.385 0.202 0.6945 1.63 0.768 3.48 PRS_PLINK_2.51188643150958e.06 FALSE 713 Arthropathy associated with other disorders classified elsewhere Both 188 422 14 musculoskeletal darkolivegreen 422, 188 106, 50 105, 39 105, 54 106, 45 -0.000829 0.0899 0.993 0.003204 0.999 0.838 1.19 -0.254 0.268 0.345 0.4628 0.776 0.459 1.31 0.0971 0.25 0.698 0.156 1.1 0.675 1.8 0.012 0.261 0.963 0.01622 1.01 0.607 1.69 PRS_PLINK_2.51188643150958e.06 FALSE 713.5 Arthropathy associated with neurological disorders Both 112 297 14 musculoskeletal darkolivegreen 297, 112 75, 32 74, 25 74, 28 74, 27 0.0932 0.122 0.447 0.3499 1.1 0.863 1.4 -0.328 0.345 0.342 0.4659 0.72 0.366 1.42 -0.0997 0.32 0.756 0.1217 0.905 0.483 1.7 -0.0842 0.327 0.797 0.09875 0.919 0.485 1.74 PRS_PLINK_2.51188643150958e.06 FALSE 714 Rheumatoid arthritis and other inflammatory polyarthropathies Both 709 2259 14 musculoskeletal darkolivegreen 2259, 709 565, 203 565, 171 564, 166 565, 169 -0.043 0.042 0.307 0.5135 0.958 0.882 1.04 -0.189 0.121 0.119 0.9253 0.828 0.653 1.05 -0.211 0.121 0.0813 1.09 0.81 0.639 1.03 -0.165 0.121 0.173 0.763 0.848 0.669 1.07 PRS_PLINK_2.51188643150958e.06 FALSE 714.1 Rheumatoid arthritis Both 528 1881 14 musculoskeletal darkolivegreen 1881, 528 471, 156 470, 133 470, 122 470, 117 -0.0766 0.0483 0.113 0.9476 0.926 0.843 1.02 -0.17 0.137 0.214 0.6704 0.843 0.645 1.1 -0.255 0.138 0.0648 1.189 0.775 0.592 1.02 -0.261 0.14 0.0627 1.202 0.771 0.586 1.01 PRS_PLINK_2.51188643150958e.06 FALSE 714.2 Juvenile rheumatoid arthritis Both 27 95 14 musculoskeletal darkolivegreen 95, 27 24, 6 24, 6 23, 6 24, 9 0.282 0.245 0.251 0.6007 1.33 0.82 2.14 0.243 0.723 0.737 0.1323 1.27 0.309 5.26 0.598 0.752 0.426 0.3705 1.82 0.417 7.94 0.465 0.671 0.488 0.3118 1.59 0.428 5.93 PRS_PLINK_2.51188643150958e.06 TRUE 715 Other inflammatory spondylopathies Both 499 1480 14 musculoskeletal darkolivegreen 1480, 499 370, 138 370, 139 370, 102 370, 120 -0.00165 0.0518 0.975 0.01119 0.998 0.902 1.11 0.028 0.142 0.843 0.07402 1.03 0.779 1.36 -0.32 0.151 0.0336 1.473 0.726 0.54 0.975 -0.109 0.146 0.455 0.3419 0.896 0.673 1.19 PRS_PLINK_2.51188643150958e.06 FALSE 715.1 Sacroiliitis NEC Both 116 296 14 musculoskeletal darkolivegreen 296, 116 74, 27 74, 32 74, 31 74, 26 -0.00469 0.112 0.967 0.01474 0.995 0.799 1.24 0.203 0.314 0.519 0.285 1.22 0.662 2.27 0.0753 0.315 0.811 0.0911 1.08 0.582 2 -0.0315 0.332 0.924 0.03413 0.969 0.505 1.86 PRS_PLINK_2.51188643150958e.06 FALSE 715.2 Ankylosing spondylitis Both 69 254 14 musculoskeletal darkolivegreen 254, 69 64, 18 63, 19 63, 15 64, 17 0.00943 0.138 0.946 0.02428 1.01 0.77 1.32 0.0432 0.383 0.91 0.04087 1.04 0.493 2.21 -0.195 0.403 0.628 0.2023 0.823 0.374 1.81 -0.0984 0.417 0.814 0.08954 0.906 0.4 2.05 PRS_PLINK_2.51188643150958e.06 FALSE 716 Other arthropathies Both 3548 3503 14 musculoskeletal darkolivegreen 3503, 3548 876, 914 876, 909 875, 846 876, 878 -0.00262 0.0252 0.917 0.03766 0.997 0.949 1.05 -0.0195 0.0709 0.784 0.1058 0.981 0.853 1.13 -0.0977 0.0713 0.171 0.7678 0.907 0.789 1.04 -0.0237 0.0712 0.74 0.1309 0.977 0.849 1.12 PRS_PLINK_2.51188643150958e.06 FALSE 716.1 Unspecified polyarthropathy or polyarthritis Both 85 238 14 musculoskeletal darkolivegreen 238, 85 60, 25 59, 21 59, 17 60, 22 -0.00925 0.138 0.947 0.02387 0.991 0.756 1.3 -0.202 0.36 0.575 0.2406 0.817 0.403 1.66 -0.428 0.384 0.265 0.5771 0.652 0.307 1.38 -0.0898 0.365 0.806 0.09393 0.914 0.447 1.87 PRS_PLINK_2.51188643150958e.06 FALSE 716.2 Unspecified monoarthritis Both 40 136 14 musculoskeletal darkolivegreen 136, 40 34, 14 34, 11 34, 10 34, 5 -0.223 0.188 0.235 0.6288 0.8 0.553 1.16 -0.118 0.488 0.809 0.092 0.889 0.341 2.31 -0.0907 0.5 0.856 0.06746 0.913 0.343 2.43 -0.904 0.578 0.118 0.9278 0.405 0.13 1.26 PRS_PLINK_2.51188643150958e.06 TRUE 716.9 Arthropathy NOS Both 3524 3502 14 musculoskeletal darkolivegreen 3502, 3524 876, 907 875, 906 875, 842 876, 868 -0.00289 0.0252 0.909 0.04151 0.997 0.949 1.05 -0.0106 0.0711 0.882 0.0547 0.989 0.861 1.14 -0.0923 0.0714 0.196 0.707 0.912 0.793 1.05 -0.0234 0.0714 0.743 0.1288 0.977 0.849 1.12 PRS_PLINK_2.51188643150958e.06 FALSE 717 Polymyalgia Rheumatica Both 102 517 14 musculoskeletal darkolivegreen 517, 102 130, 27 129, 24 129, 26 129, 25 -0.0843 0.114 0.459 0.3383 0.919 0.735 1.15 -0.187 0.31 0.545 0.2637 0.829 0.452 1.52 -0.0639 0.3 0.832 0.08013 0.938 0.521 1.69 -0.0778 0.303 0.798 0.09821 0.925 0.51 1.68 PRS_PLINK_2.51188643150958e.06 FALSE 720 Spinal stenosis Both 1276 3424 14 musculoskeletal darkolivegreen 3424, 1276 855, 318 856, 335 856, 298 856, 325 0.0135 0.0337 0.687 0.1627 1.01 0.949 1.08 0.0397 0.0949 0.676 0.17 1.04 0.864 1.25 -0.07 0.0967 0.469 0.329 0.932 0.771 1.13 0.0432 0.0958 0.652 0.1856 1.04 0.865 1.26 PRS_PLINK_2.51188643150958e.06 FALSE 720.1 Spinal stenosis of lumbar region Both 937 2871 14 musculoskeletal darkolivegreen 2871, 937 717, 234 718, 240 717, 224 718, 239 0.0276 0.0386 0.476 0.3228 1.03 0.953 1.11 0.0134 0.109 0.902 0.04463 1.01 0.818 1.26 -0.0388 0.109 0.722 0.1412 0.962 0.776 1.19 0.0595 0.109 0.586 0.2318 1.06 0.857 1.31 PRS_PLINK_2.51188643150958e.06 FALSE 721 Spondylosis and allied disorders Both 2047 3887 14 musculoskeletal darkolivegreen 3887, 2047 971, 530 972, 534 971, 496 972, 487 -0.000118 0.0283 0.997 0.001447 1 0.946 1.06 -0.0144 0.0792 0.855 0.06788 0.986 0.844 1.15 -0.0723 0.08 0.367 0.4359 0.93 0.795 1.09 -0.0582 0.0805 0.469 0.3286 0.943 0.806 1.1 PRS_PLINK_2.51188643150958e.06 FALSE 721.1 Spondylosis without myelopathy Both 1947 3831 14 musculoskeletal darkolivegreen 3831, 1947 957, 499 958, 507 957, 467 958, 474 0.00283 0.0288 0.922 0.03534 1 0.948 1.06 -0.00317 0.0808 0.969 0.01381 0.997 0.851 1.17 -0.0729 0.0819 0.373 0.4281 0.93 0.792 1.09 -0.0289 0.0818 0.724 0.1405 0.971 0.828 1.14 PRS_PLINK_2.51188643150958e.06 FALSE 721.2 Spondylosis with myelopathy Both 295 1054 14 musculoskeletal darkolivegreen 1054, 295 264, 68 263, 77 263, 70 264, 80 0.0118 0.0632 0.852 0.06961 1.01 0.894 1.15 0.181 0.191 0.342 0.4656 1.2 0.825 1.74 0.0471 0.195 0.809 0.09218 1.05 0.716 1.53 0.174 0.189 0.358 0.4464 1.19 0.822 1.72 PRS_PLINK_2.51188643150958e.06 FALSE 721.8 Other allied disorders of spine Both 113 334 14 musculoskeletal darkolivegreen 334, 113 84, 31 83, 26 83, 32 84, 24 -0.0412 0.118 0.726 0.1389 0.96 0.762 1.21 -0.166 0.313 0.597 0.2242 0.847 0.458 1.57 0.0862 0.299 0.773 0.1118 1.09 0.607 1.96 -0.327 0.321 0.309 0.5098 0.721 0.384 1.35 PRS_PLINK_2.51188643150958e.06 FALSE 722 Intervertebral disc disorders Both 2042 4026 14 musculoskeletal darkolivegreen 4026, 2042 1006, 510 1006, 515 1006, 505 1007, 512 0.0184 0.0279 0.51 0.2924 1.02 0.964 1.08 -0.0029 0.0787 0.971 0.01295 0.997 0.855 1.16 -0.0109 0.0788 0.89 0.05042 0.989 0.848 1.15 0.0124 0.0791 0.875 0.05791 1.01 0.867 1.18 PRS_PLINK_2.51188643150958e.06 FALSE 722.1 Displacement of intervertebral disc Both 1175 3729 14 musculoskeletal darkolivegreen 3729, 1175 932, 294 932, 304 932, 296 932, 281 -0.0024 0.0338 0.943 0.02528 0.998 0.934 1.07 0.0214 0.0952 0.822 0.08521 1.02 0.848 1.23 0.0119 0.0955 0.901 0.04525 1.01 0.839 1.22 -0.0314 0.0969 0.746 0.1272 0.969 0.801 1.17 PRS_PLINK_2.51188643150958e.06 FALSE 722.3 Schmorl's nodes Both 57 129 14 musculoskeletal darkolivegreen 129, 57 33, 13 32, 22 32, 14 32, 8 -0.0446 0.172 0.795 0.09953 0.956 0.683 1.34 0.489 0.451 0.279 0.5551 1.63 0.673 3.95 -0.0129 0.471 0.978 0.009627 0.987 0.393 2.48 -0.221 0.584 0.705 0.1519 0.802 0.255 2.52 PRS_PLINK_2.51188643150958e.06 FALSE 722.6 Degeneration of intervertebral disc Both 1394 3683 14 musculoskeletal darkolivegreen 3683, 1394 920, 336 921, 345 920, 338 921, 375 0.0402 0.0326 0.218 0.662 1.04 0.977 1.11 0.0288 0.0918 0.754 0.1228 1.03 0.86 1.23 0.0036 0.0922 0.969 0.01375 1 0.838 1.2 0.125 0.0906 0.168 0.7735 1.13 0.949 1.35 PRS_PLINK_2.51188643150958e.06 FALSE 722.7 Intervertebral disc disorder with myelopathy Both 167 589 14 musculoskeletal darkolivegreen 589, 167 148, 44 147, 41 147, 40 147, 42 0.0269 0.0918 0.769 0.1139 1.03 0.858 1.23 0.0642 0.252 0.799 0.09746 1.07 0.651 1.75 -0.0449 0.253 0.859 0.06585 0.956 0.582 1.57 0.0265 0.249 0.915 0.03848 1.03 0.63 1.67 PRS_PLINK_2.51188643150958e.06 FALSE 722.8 Postlaminectomy syndrome Both 131 487 14 musculoskeletal darkolivegreen 487, 131 122, 21 122, 39 121, 38 122, 33 0.153 0.107 0.153 0.8155 1.17 0.945 1.44 0.543 0.306 0.0758 1.121 1.72 0.945 3.13 0.573 0.301 0.0566 1.247 1.77 0.984 3.2 0.439 0.311 0.158 0.801 1.55 0.843 2.85 PRS_PLINK_2.51188643150958e.06 FALSE 722.9 Other and unspecified disc disorder Both 643 2365 14 musculoskeletal darkolivegreen 2365, 643 592, 151 591, 181 591, 156 591, 155 0.0193 0.0442 0.662 0.1792 1.02 0.935 1.11 0.176 0.125 0.161 0.7936 1.19 0.932 1.52 0.0256 0.128 0.842 0.07473 1.03 0.798 1.32 0.0406 0.129 0.753 0.1232 1.04 0.809 1.34 PRS_PLINK_2.51188643150958e.06 FALSE 723 Other disorders of cervical region Both 351 1142 14 musculoskeletal darkolivegreen 1142, 351 286, 99 285, 82 285, 79 286, 91 0.0165 0.0621 0.791 0.1018 1.02 0.9 1.15 -0.15 0.173 0.386 0.4135 0.861 0.614 1.21 -0.2 0.173 0.249 0.6036 0.819 0.583 1.15 -0.067 0.169 0.692 0.1596 0.935 0.671 1.3 PRS_PLINK_2.51188643150958e.06 FALSE 723.1 Torticollis Both 77 309 14 musculoskeletal darkolivegreen 309, 77 78, 20 77, 15 77, 18 77, 24 0.195 0.148 0.186 0.7301 1.22 0.91 1.62 -0.222 0.387 0.566 0.2472 0.801 0.375 1.71 0.043 0.368 0.907 0.04241 1.04 0.507 2.15 0.153 0.347 0.66 0.1805 1.16 0.59 2.3 PRS_PLINK_2.51188643150958e.06 FALSE 724 Other and unspecified disorders of back Both 1493 3806 14 musculoskeletal darkolivegreen 3806, 1493 951, 366 951, 373 951, 395 952, 359 0.0212 0.0313 0.497 0.3034 1.02 0.961 1.09 0.00814 0.088 0.926 0.03327 1.01 0.849 1.2 0.0755 0.0871 0.386 0.4137 1.08 0.909 1.28 0.00846 0.0889 0.924 0.03424 1.01 0.847 1.2 PRS_PLINK_2.51188643150958e.06 FALSE 724.1 Disorders of sacrum Both 915 2762 14 musculoskeletal darkolivegreen 2762, 915 691, 239 690, 213 690, 234 691, 229 0.00476 0.0396 0.904 0.04369 1 0.93 1.09 -0.109 0.109 0.32 0.4945 0.897 0.724 1.11 -0.00635 0.107 0.953 0.02098 0.994 0.805 1.23 -0.0204 0.108 0.851 0.07029 0.98 0.793 1.21 PRS_PLINK_2.51188643150958e.06 FALSE 724.2 Disorders of coccyx Both 200 541 14 musculoskeletal darkolivegreen 541, 200 136, 55 135, 40 135, 51 135, 54 -0.0468 0.0842 0.579 0.2374 0.954 0.809 1.13 -0.218 0.246 0.377 0.4239 0.804 0.496 1.3 0.019 0.235 0.935 0.02896 1.02 0.643 1.62 -0.0116 0.231 0.96 0.01779 0.988 0.629 1.55 PRS_PLINK_2.51188643150958e.06 FALSE 724.8 Other symptoms referable to back Both 334 1153 14 musculoskeletal darkolivegreen 1153, 334 289, 80 288, 82 288, 92 288, 80 0.101 0.0655 0.125 0.9046 1.11 0.973 1.26 0.018 0.179 0.92 0.03625 1.02 0.717 1.45 0.131 0.175 0.456 0.3412 1.14 0.808 1.61 0.036 0.181 0.842 0.07451 1.04 0.727 1.48 PRS_PLINK_2.51188643150958e.06 FALSE 724.9 Other unspecified back disorders Both 432 1680 14 musculoskeletal darkolivegreen 1680, 432 420, 115 420, 110 420, 109 420, 98 -0.0577 0.053 0.276 0.559 0.944 0.851 1.05 -0.0197 0.152 0.897 0.04708 0.981 0.728 1.32 -0.0384 0.152 0.8 0.09674 0.962 0.715 1.3 -0.125 0.155 0.423 0.3741 0.883 0.651 1.2 PRS_PLINK_2.51188643150958e.06 FALSE 726 Peripheral enthesopathies and allied syndromes Both 3115 2710 14 musculoskeletal darkolivegreen 2710, 3115 678, 775 677, 788 677, 777 678, 775 0.021 0.027 0.437 0.3593 1.02 0.969 1.08 0.00543 0.0767 0.944 0.02524 1.01 0.865 1.17 0.0137 0.0768 0.858 0.06652 1.01 0.872 1.18 0.0386 0.0773 0.618 0.209 1.04 0.893 1.21 PRS_PLINK_2.51188643150958e.06 FALSE 726.1 Enthesopathy Both 2385 2703 14 musculoskeletal darkolivegreen 2703, 2385 676, 605 676, 576 675, 609 676, 595 0.0104 0.0288 0.718 0.1439 1.01 0.955 1.07 -0.0744 0.0827 0.368 0.4336 0.928 0.789 1.09 0.0044 0.0822 0.957 0.01896 1 0.855 1.18 0.0209 0.0831 0.801 0.09614 1.02 0.868 1.2 PRS_PLINK_2.51188643150958e.06 FALSE 726.2 Synoviopathy Both 325 943 14 musculoskeletal darkolivegreen 943, 325 236, 75 236, 88 235, 85 236, 77 0.0323 0.0666 0.627 0.2025 1.03 0.906 1.18 0.173 0.185 0.35 0.4563 1.19 0.827 1.71 0.119 0.186 0.522 0.2827 1.13 0.782 1.62 0.0759 0.189 0.689 0.162 1.08 0.744 1.56 PRS_PLINK_2.51188643150958e.06 FALSE 726.3 Bursitis Both 697 1618 14 musculoskeletal darkolivegreen 1618, 697 405, 195 404, 177 404, 184 405, 141 -0.0629 0.0451 0.163 0.788 0.939 0.86 1.03 -0.0661 0.127 0.603 0.2195 0.936 0.729 1.2 -0.0472 0.127 0.71 0.1489 0.954 0.744 1.22 -0.277 0.134 0.0386 1.413 0.758 0.583 0.986 PRS_PLINK_2.51188643150958e.06 FALSE 726.4 Calcaneal spur; Exostosis NOS Both 417 1111 14 musculoskeletal darkolivegreen 1111, 417 278, 106 278, 108 277, 106 278, 97 -0.0178 0.0577 0.758 0.1204 0.982 0.877 1.1 0.0325 0.164 0.843 0.07431 1.03 0.749 1.42 -0.0235 0.163 0.885 0.0529 0.977 0.709 1.35 -0.0676 0.168 0.688 0.1624 0.935 0.672 1.3 PRS_PLINK_2.51188643150958e.06 FALSE 727 Other disorders of synovium, tendon, and bursa Both 2319 2700 14 musculoskeletal darkolivegreen 2700, 2319 675, 581 675, 583 675, 589 675, 566 0.0279 0.0293 0.341 0.4672 1.03 0.971 1.09 -0.0148 0.0832 0.859 0.06596 0.985 0.837 1.16 0.0194 0.083 0.816 0.08849 1.02 0.866 1.2 0.0355 0.084 0.672 0.1724 1.04 0.879 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 727.1 Synovitis and tenosynovitis Both 1067 2338 14 musculoskeletal darkolivegreen 2338, 1067 585, 275 584, 264 584, 252 585, 276 0.0235 0.0375 0.531 0.2747 1.02 0.951 1.1 -0.0816 0.108 0.448 0.3489 0.922 0.746 1.14 -0.101 0.108 0.351 0.4552 0.904 0.731 1.12 0.0554 0.107 0.604 0.2187 1.06 0.857 1.3 PRS_PLINK_2.51188643150958e.06 FALSE 727.2 Bursitis disorders Both 172 435 14 musculoskeletal darkolivegreen 435, 172 109, 42 109, 40 108, 49 109, 41 0.0267 0.0859 0.756 0.1216 1.03 0.868 1.22 0.0236 0.272 0.931 0.03114 1.02 0.601 1.74 0.219 0.258 0.396 0.4022 1.24 0.751 2.06 0.122 0.269 0.651 0.1867 1.13 0.667 1.91 PRS_PLINK_2.51188643150958e.06 FALSE 727.4 Ganglion and cyst of synovium, tendon, and bursa Both 475 1341 14 musculoskeletal darkolivegreen 1341, 475 336, 122 335, 123 335, 124 335, 106 -0.043 0.0527 0.414 0.3831 0.958 0.864 1.06 -0.00425 0.152 0.978 0.009817 0.996 0.74 1.34 -0.0271 0.151 0.858 0.06664 0.973 0.724 1.31 -0.15 0.156 0.336 0.4736 0.86 0.633 1.17 PRS_PLINK_2.51188643150958e.06 FALSE 727.5 Rupture of synovium Both 195 426 14 musculoskeletal darkolivegreen 426, 195 107, 60 106, 46 106, 43 107, 46 -0.0624 0.0888 0.483 0.3165 0.94 0.789 1.12 -0.181 0.251 0.471 0.3266 0.834 0.51 1.37 -0.347 0.249 0.162 0.7894 0.707 0.434 1.15 -0.152 0.247 0.539 0.2686 0.859 0.53 1.39 PRS_PLINK_2.51188643150958e.06 FALSE 727.6 Rupture of tendon, nontraumatic Both 760 2020 14 musculoskeletal darkolivegreen 2020, 760 505, 203 505, 184 505, 186 505, 187 -0.0167 0.0426 0.695 0.1581 0.983 0.905 1.07 -0.125 0.122 0.306 0.5148 0.882 0.694 1.12 -0.0718 0.121 0.554 0.2568 0.931 0.734 1.18 -0.035 0.123 0.775 0.1108 0.966 0.759 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 727.7 Contracture of tendon (sheath) Both 197 554 14 musculoskeletal darkolivegreen 554, 197 139, 48 138, 52 138, 60 139, 37 -0.0347 0.0837 0.678 0.1687 0.966 0.82 1.14 -0.0107 0.242 0.965 0.0156 0.989 0.616 1.59 0.168 0.235 0.474 0.3246 1.18 0.747 1.88 -0.218 0.259 0.399 0.3986 0.804 0.484 1.34 PRS_PLINK_2.51188643150958e.06 FALSE 727.8 Plica syndrome Both 22 91 14 musculoskeletal darkolivegreen 91, 22 23, 6 23, 6 22, 6 23, 4 -0.138 0.22 0.53 0.2757 0.871 0.566 1.34 -0.0447 0.744 0.952 0.02135 0.956 0.223 4.11 -0.151 0.695 0.828 0.08178 0.86 0.22 3.36 -0.579 0.752 0.441 0.3553 0.56 0.128 2.45 PRS_PLINK_2.51188643150958e.06 TRUE 728 Disorders of muscle, ligament, and fascia Both 1594 2671 14 musculoskeletal darkolivegreen 2671, 1594 668, 410 668, 390 667, 432 668, 361 -0.00451 0.0325 0.89 0.05078 0.996 0.934 1.06 -0.0672 0.0916 0.463 0.3343 0.935 0.781 1.12 0.0534 0.09 0.553 0.2573 1.05 0.884 1.26 -0.0994 0.0935 0.287 0.5415 0.905 0.754 1.09 PRS_PLINK_2.51188643150958e.06 FALSE 728.1 Muscular calcification and ossification Both 22 82 14 musculoskeletal darkolivegreen 82, 22 21, 10 20, 4 20, 4 21, 4 -0.588 0.241 0.0148 1.83 0.555 0.346 0.891 -1 0.719 0.164 0.7846 0.368 0.0898 1.51 -1.19 0.73 0.103 0.9876 0.304 0.0728 1.27 -0.98 0.678 0.148 0.8289 0.375 0.0995 1.42 PRS_PLINK_2.51188643150958e.06 TRUE 728.2 Laxity of ligament or hypermobility syndrome Both 94 271 14 musculoskeletal darkolivegreen 271, 94 68, 23 68, 29 67, 20 68, 22 0.0118 0.117 0.92 0.03643 1.01 0.804 1.27 0.373 0.341 0.275 0.5604 1.45 0.743 2.83 0.0589 0.373 0.874 0.05831 1.06 0.511 2.2 -0.0167 0.367 0.964 0.01604 0.983 0.479 2.02 PRS_PLINK_2.51188643150958e.06 FALSE 728.7 Fasciitis Both 1034 2228 14 musculoskeletal darkolivegreen 2228, 1034 557, 255 557, 252 557, 270 557, 257 0.0417 0.0388 0.282 0.5502 1.04 0.966 1.12 -0.0209 0.109 0.848 0.07168 0.979 0.791 1.21 0.0521 0.108 0.628 0.202 1.05 0.853 1.3 0.0143 0.108 0.895 0.04811 1.01 0.82 1.25 PRS_PLINK_2.51188643150958e.06 FALSE 728.71 Contracture of palmar fascia [Dupuytren's disease] Both 143 468 14 musculoskeletal darkolivegreen 468, 143 117, 40 117, 36 117, 41 117, 26 0.00595 0.0954 0.95 0.02214 1.01 0.834 1.21 -0.176 0.27 0.514 0.2887 0.839 0.494 1.42 -0.0536 0.264 0.839 0.07599 0.948 0.564 1.59 -0.395 0.289 0.173 0.7628 0.674 0.382 1.19 PRS_PLINK_2.51188643150958e.06 FALSE 729 Other disorders of soft tissues Both 1346 2541 14 musculoskeletal darkolivegreen 2541, 1346 636, 345 635, 315 635, 357 635, 329 0.00353 0.0339 0.917 0.03759 1 0.939 1.07 -0.12 0.0988 0.225 0.6471 0.887 0.731 1.08 0.0344 0.0962 0.72 0.1424 1.04 0.857 1.25 -0.0266 0.0979 0.786 0.1046 0.974 0.804 1.18 PRS_PLINK_2.51188643150958e.06 FALSE 729.1 Rheumatism, unspecified and fibrositis Both 34 83 14 musculoskeletal darkolivegreen 83, 34 21, 12 21, 17 20, 3 21, 2 -0.433 0.261 0.0972 1.013 0.648 0.388 1.08 0.394 0.517 0.446 0.3508 1.48 0.539 4.08 -0.939 0.777 0.227 0.6447 0.391 0.0854 1.79 -1.69 0.862 0.0502 1.3 0.185 0.0341 1 PRS_PLINK_2.51188643150958e.06 TRUE 729.3 Panniculitis Both 47 120 14 musculoskeletal darkolivegreen 120, 47 30, 12 30, 11 30, 14 30, 10 -0.196 0.211 0.353 0.4528 0.822 0.543 1.24 -0.171 0.511 0.737 0.1323 0.842 0.309 2.3 0.19 0.521 0.716 0.1452 1.21 0.435 3.36 -0.221 0.564 0.695 0.158 0.802 0.265 2.42 PRS_PLINK_2.51188643150958e.06 TRUE 729.7 Nontraumatic compartment syndrome Both 15 60 14 musculoskeletal darkolivegreen 60, 15 15, 6 15, 2 15, 4 15, 3 -0.277 0.297 0.35 0.4555 0.758 0.423 1.36 -1.23 0.982 0.21 0.6782 0.292 0.0425 2 -0.432 0.889 0.627 0.2025 0.649 0.114 3.71 -0.998 0.878 0.255 0.5927 0.369 0.066 2.06 PRS_PLINK_2.51188643150958e.06 TRUE 731 Osteitis deformans and osteopathies associated with other disorders classified elsewhere Both 94 334 14 musculoskeletal darkolivegreen 334, 94 84, 29 83, 22 83, 22 84, 21 -0.117 0.111 0.29 0.5379 0.889 0.715 1.11 -0.254 0.331 0.444 0.353 0.776 0.406 1.48 -0.373 0.345 0.279 0.5541 0.689 0.35 1.35 -0.382 0.336 0.255 0.5939 0.682 0.353 1.32 PRS_PLINK_2.51188643150958e.06 FALSE 732 Osteochondropathies Both 72 395 14 musculoskeletal darkolivegreen 395, 72 99, 21 99, 21 98, 9 99, 21 -0.145 0.134 0.278 0.5556 0.865 0.665 1.12 -0.0826 0.343 0.81 0.09176 0.921 0.47 1.8 -0.979 0.432 0.0232 1.634 0.376 0.161 0.875 -0.0823 0.344 0.811 0.09087 0.921 0.469 1.81 PRS_PLINK_2.51188643150958e.06 FALSE 732.1 Juvenile osteochondrosis Both 51 226 14 musculoskeletal darkolivegreen 226, 51 57, 18 56, 13 56, 4 57, 16 -0.189 0.16 0.236 0.6266 0.828 0.605 1.13 -0.477 0.437 0.276 0.5597 0.621 0.264 1.46 -2.35 0.719 0.00106 2.973 0.095 0.0232 0.389 -0.309 0.435 0.476 0.322 0.734 0.313 1.72 PRS_PLINK_2.51188643150958e.06 FALSE 732.7 Osteochondritis dissecans Both 14 109 14 musculoskeletal darkolivegreen 109, 14 28, 2 27, 4 27, 3 27, 5 0.564 0.386 0.144 0.8421 1.76 0.825 3.75 0.782 0.935 0.403 0.3951 2.19 0.35 13.7 0.681 0.917 0.458 0.3392 1.98 0.327 11.9 1.48 0.925 0.11 0.9586 4.39 0.716 26.9 PRS_PLINK_2.51188643150958e.06 TRUE 733 Other disorders of bone and cartilage Both 1570 3404 14 musculoskeletal darkolivegreen 3404, 1570 850, 406 851, 420 851, 367 851, 377 0.00456 0.0321 0.887 0.0521 1 0.943 1.07 0.00711 0.0895 0.937 0.02841 1.01 0.845 1.2 -0.0922 0.0916 0.315 0.5023 0.912 0.762 1.09 -0.0554 0.0914 0.545 0.2639 0.946 0.791 1.13 PRS_PLINK_2.51188643150958e.06 FALSE 733.2 Cyst of bone Both 43 222 14 musculoskeletal darkolivegreen 222, 43 56, 13 55, 14 55, 7 56, 9 -0.00561 0.184 0.976 0.0107 0.994 0.694 1.43 -0.0565 0.443 0.898 0.04649 0.945 0.397 2.25 -0.618 0.539 0.252 0.5987 0.539 0.187 1.55 -0.281 0.505 0.577 0.2387 0.755 0.281 2.03 PRS_PLINK_2.51188643150958e.06 TRUE 733.4 Aseptic necrosis of bone Both 155 632 14 musculoskeletal darkolivegreen 632, 155 158, 50 158, 31 158, 33 158, 41 -0.0685 0.0867 0.429 0.3675 0.934 0.788 1.11 -0.394 0.261 0.13 0.8845 0.674 0.404 1.12 -0.361 0.256 0.159 0.7989 0.697 0.422 1.15 -0.15 0.242 0.535 0.2717 0.861 0.536 1.38 PRS_PLINK_2.51188643150958e.06 FALSE 733.6 Costochondritis Both 144 462 14 musculoskeletal darkolivegreen 462, 144 116, 43 115, 40 115, 28 116, 33 -0.0916 0.0961 0.34 0.4683 0.912 0.756 1.1 -0.101 0.262 0.699 0.1556 0.904 0.541 1.51 -0.451 0.28 0.108 0.9685 0.637 0.368 1.1 -0.321 0.27 0.235 0.6292 0.726 0.427 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 733.8 Malunion and nonunion of fracture Both 178 990 14 musculoskeletal darkolivegreen 990, 178 248, 47 247, 45 247, 38 248, 48 0.0761 0.0869 0.381 0.4187 1.08 0.91 1.28 -0.193 0.234 0.41 0.3874 0.824 0.521 1.3 -0.249 0.236 0.293 0.533 0.78 0.491 1.24 0.0321 0.224 0.886 0.05239 1.03 0.665 1.6 PRS_PLINK_2.51188643150958e.06 FALSE 733.9 Chondromalacia Both 21 97 14 musculoskeletal darkolivegreen 97, 21 25, 3 24, 8 24, 2 24, 8 0.258 0.303 0.395 0.4038 1.29 0.714 2.35 0.805 0.737 0.275 0.5612 2.24 0.528 9.48 -0.38 0.884 0.668 0.1754 0.684 0.121 3.87 0.856 0.802 0.286 0.5443 2.35 0.489 11.3 PRS_PLINK_2.51188643150958e.06 TRUE 735 Acquired foot deformities Both 1231 4316 14 musculoskeletal darkolivegreen 4316, 1231 1078, 315 1079, 291 1079, 296 1079, 329 0.0201 0.033 0.542 0.266 1.02 0.956 1.09 -0.0893 0.0933 0.339 0.47 0.915 0.762 1.1 -0.0556 0.0928 0.549 0.2606 0.946 0.789 1.13 0.0602 0.0911 0.509 0.2933 1.06 0.888 1.27 PRS_PLINK_2.51188643150958e.06 FALSE 735.1 Flat foot Both 229 931 14 musculoskeletal darkolivegreen 931, 229 232, 63 233, 47 232, 50 233, 69 0.0549 0.0724 0.449 0.3482 1.06 0.917 1.22 -0.331 0.215 0.124 0.9065 0.718 0.471 1.09 -0.187 0.213 0.378 0.4224 0.829 0.546 1.26 0.0882 0.198 0.656 0.1833 1.09 0.741 1.61 PRS_PLINK_2.51188643150958e.06 FALSE 735.2 Acquired toe deformities Both 539 1908 14 musculoskeletal darkolivegreen 1908, 539 477, 144 477, 130 477, 113 477, 152 0.00104 0.0494 0.983 0.007388 1 0.909 1.1 -0.086 0.138 0.533 0.2732 0.918 0.7 1.2 -0.222 0.143 0.121 0.9178 0.801 0.605 1.06 0.0785 0.135 0.56 0.2517 1.08 0.831 1.41 PRS_PLINK_2.51188643150958e.06 FALSE 735.21 Hammer toe (acquired) Both 374 1284 14 musculoskeletal darkolivegreen 1284, 374 321, 105 321, 80 321, 90 321, 99 -0.0254 0.0597 0.671 0.1734 0.975 0.867 1.1 -0.27 0.169 0.11 0.9575 0.763 0.548 1.06 -0.137 0.165 0.408 0.3897 0.872 0.631 1.21 -0.0654 0.162 0.687 0.1628 0.937 0.681 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 735.23 Hallux rigidus Both 133 639 14 musculoskeletal darkolivegreen 639, 133 160, 31 160, 38 159, 23 160, 41 0.0645 0.103 0.53 0.2753 1.07 0.872 1.31 0.195 0.268 0.466 0.3312 1.22 0.718 2.06 -0.285 0.298 0.337 0.4717 0.752 0.42 1.35 0.329 0.269 0.22 0.6571 1.39 0.821 2.35 PRS_PLINK_2.51188643150958e.06 FALSE 735.3 Hallux valgus (Bunion) Both 508 2268 14 musculoskeletal darkolivegreen 2268, 508 567, 127 567, 111 567, 115 567, 155 0.0366 0.051 0.474 0.3245 1.04 0.939 1.15 -0.142 0.143 0.324 0.4901 0.868 0.655 1.15 -0.117 0.143 0.413 0.3836 0.89 0.673 1.18 0.213 0.135 0.114 0.9439 1.24 0.95 1.61 PRS_PLINK_2.51188643150958e.06 FALSE 736 Other acquired deformities of limbs Both 892 3816 14 musculoskeletal darkolivegreen 3816, 892 954, 243 954, 209 954, 204 954, 236 -0.00518 0.0379 0.891 0.04999 0.995 0.924 1.07 -0.147 0.105 0.164 0.784 0.864 0.702 1.06 -0.162 0.106 0.127 0.895 0.851 0.691 1.05 -0.00454 0.103 0.965 0.01553 0.995 0.813 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 736.1 Acquired deformities of forearm Both 31 151 14 musculoskeletal darkolivegreen 151, 31 38, 14 38, 6 37, 6 38, 5 -0.215 0.183 0.24 0.6201 0.807 0.564 1.15 -0.748 0.541 0.166 0.7793 0.473 0.164 1.36 -0.643 0.538 0.233 0.6332 0.526 0.183 1.51 -0.833 0.567 0.142 0.8487 0.435 0.143 1.32 PRS_PLINK_2.51188643150958e.06 TRUE 736.2 Acquired deformities of finger Both 62 277 14 musculoskeletal darkolivegreen 277, 62 70, 20 69, 14 69, 13 69, 15 -0.168 0.153 0.273 0.5645 0.846 0.627 1.14 -0.252 0.383 0.511 0.2919 0.777 0.367 1.65 -0.394 0.393 0.316 0.5009 0.674 0.312 1.46 -0.126 0.39 0.747 0.1266 0.882 0.411 1.89 PRS_PLINK_2.51188643150958e.06 FALSE 736.3 Acquired deformities of hip Both 16 69 14 musculoskeletal darkolivegreen 69, 16 18, 6 17, 3 17, 3 17, 4 -0.0456 0.293 0.876 0.05737 0.955 0.538 1.7 -0.00787 0.822 0.992 0.00333 0.992 0.198 4.97 -0.841 1.18 0.475 0.3235 0.431 0.043 4.33 0.101 0.802 0.899 0.04603 1.11 0.23 5.33 PRS_PLINK_2.51188643150958e.06 TRUE 736.4 Genu valgum or varum (acquired) Both 80 462 14 musculoskeletal darkolivegreen 462, 80 116, 27 115, 22 115, 13 116, 18 -0.187 0.113 0.0983 1.008 0.829 0.665 1.04 -0.182 0.325 0.574 0.2411 0.833 0.441 1.57 -0.664 0.364 0.0685 1.164 0.515 0.252 1.05 -0.432 0.34 0.204 0.6903 0.649 0.333 1.26 PRS_PLINK_2.51188643150958e.06 FALSE 736.5 Acquired deformities of knee Both 61 337 14 musculoskeletal darkolivegreen 337, 61 85, 19 84, 16 84, 12 84, 14 -0.193 0.146 0.185 0.7323 0.824 0.619 1.1 -0.221 0.393 0.574 0.2411 0.802 0.371 1.73 -0.53 0.401 0.186 0.7301 0.588 0.268 1.29 -0.266 0.396 0.503 0.2988 0.767 0.353 1.67 PRS_PLINK_2.51188643150958e.06 FALSE 736.6 Unequal leg length (acquired) Both 114 465 14 musculoskeletal darkolivegreen 465, 114 117, 31 116, 34 116, 22 116, 27 -0.0679 0.1 0.499 0.3022 0.934 0.768 1.14 0.0585 0.279 0.834 0.07876 1.06 0.613 1.83 -0.338 0.305 0.268 0.5718 0.713 0.392 1.3 -0.195 0.296 0.51 0.2926 0.822 0.46 1.47 PRS_PLINK_2.51188643150958e.06 FALSE 737 Curvature of spine Both 439 2199 14 musculoskeletal darkolivegreen 2199, 439 550, 111 550, 109 549, 98 550, 121 0.0426 0.0534 0.425 0.3719 1.04 0.94 1.16 -0.0165 0.149 0.912 0.04002 0.984 0.735 1.32 -0.136 0.151 0.37 0.4316 0.873 0.649 1.17 0.092 0.145 0.526 0.2793 1.1 0.825 1.46 PRS_PLINK_2.51188643150958e.06 FALSE 737.1 Kyphosis (acquired) Both 133 643 14 musculoskeletal darkolivegreen 643, 133 161, 40 161, 28 160, 33 161, 32 -0.0836 0.0921 0.364 0.4387 0.92 0.768 1.1 -0.317 0.28 0.257 0.5893 0.728 0.421 1.26 -0.156 0.263 0.553 0.2569 0.856 0.511 1.43 -0.17 0.268 0.526 0.2787 0.844 0.499 1.43 PRS_PLINK_2.51188643150958e.06 FALSE 737.2 Lordosis (acquired) Both 18 98 14 musculoskeletal darkolivegreen 98, 18 25, 4 24, 5 24, 5 25, 4 -0.0266 0.285 0.926 0.0336 0.974 0.557 1.7 0.379 0.737 0.607 0.2166 1.46 0.344 6.2 0.138 0.748 0.854 0.06849 1.15 0.265 4.97 0.0249 0.717 0.972 0.0122 1.03 0.251 4.18 PRS_PLINK_2.51188643150958e.06 TRUE 737.3 Kyphoscoliosis and scoliosis Both 317 1709 14 musculoskeletal darkolivegreen 1709, 317 428, 76 427, 81 427, 67 427, 93 0.0783 0.0627 0.212 0.674 1.08 0.956 1.22 0.0481 0.174 0.782 0.1068 1.05 0.746 1.48 -0.132 0.181 0.467 0.3311 0.876 0.615 1.25 0.193 0.17 0.254 0.5945 1.21 0.87 1.69 PRS_PLINK_2.51188643150958e.06 FALSE 738 Other acquired musculoskeletal deformity Both 602 3389 14 musculoskeletal darkolivegreen 3389, 602 848, 152 847, 154 847, 137 847, 159 -0.0109 0.0443 0.806 0.09356 0.989 0.907 1.08 -0.00554 0.125 0.965 0.01569 0.994 0.779 1.27 -0.118 0.128 0.358 0.4463 0.889 0.692 1.14 0.0399 0.124 0.748 0.126 1.04 0.816 1.33 PRS_PLINK_2.51188643150958e.06 FALSE 738.4 Acquired spondylolisthesis Both 317 1588 14 musculoskeletal darkolivegreen 1588, 317 397, 99 397, 76 397, 65 397, 77 -0.0601 0.0595 0.313 0.505 0.942 0.838 1.06 -0.288 0.169 0.0882 1.055 0.75 0.538 1.04 -0.415 0.175 0.0176 1.755 0.66 0.469 0.93 -0.258 0.168 0.125 0.9043 0.773 0.556 1.07 PRS_PLINK_2.51188643150958e.06 FALSE 739 Contracture of joint Both 189 888 14 musculoskeletal darkolivegreen 888, 189 222, 51 222, 43 222, 43 222, 52 0.0134 0.0813 0.869 0.06083 1.01 0.864 1.19 -0.205 0.228 0.369 0.4327 0.815 0.521 1.27 -0.177 0.228 0.436 0.36 0.838 0.536 1.31 0.0364 0.221 0.869 0.06102 1.04 0.673 1.6 PRS_PLINK_2.51188643150958e.06 FALSE 740 Osteoarthrosis Both 4185 3252 14 musculoskeletal darkolivegreen 3252, 4185 813, 1027 813, 1138 813, 1021 813, 998 0.00842 0.0251 0.737 0.1323 1.01 0.96 1.06 0.0941 0.0708 0.184 0.7355 1.1 0.956 1.26 -0.0297 0.0714 0.678 0.169 0.971 0.844 1.12 -0.00504 0.0719 0.944 0.02499 0.995 0.864 1.15 PRS_PLINK_2.51188643150958e.06 FALSE 740.1 Osteoarthritis; localized Both 2184 3024 14 musculoskeletal darkolivegreen 3024, 2184 756, 509 756, 600 756, 552 756, 523 0.032 0.0308 0.298 0.5254 1.03 0.972 1.1 0.184 0.0869 0.0346 1.461 1.2 1.01 1.42 0.104 0.0875 0.236 0.627 1.11 0.934 1.32 0.0897 0.0888 0.313 0.5048 1.09 0.919 1.3 PRS_PLINK_2.51188643150958e.06 FALSE 740.11 Osteoarthrosis, localized, primary Both 1936 2908 14 musculoskeletal darkolivegreen 2908, 1936 727, 452 727, 529 727, 488 727, 467 0.0344 0.0323 0.288 0.5413 1.03 0.971 1.1 0.181 0.0907 0.0463 1.335 1.2 1 1.43 0.107 0.0914 0.243 0.6143 1.11 0.93 1.33 0.09 0.0924 0.33 0.4814 1.09 0.913 1.31 PRS_PLINK_2.51188643150958e.06 FALSE 740.12 Osteoarthrosis, localized, secondary Both 180 787 14 musculoskeletal darkolivegreen 787, 180 197, 37 197, 48 196, 42 197, 53 0.109 0.0868 0.207 0.6836 1.12 0.941 1.32 0.289 0.242 0.232 0.6345 1.34 0.831 2.15 0.212 0.254 0.404 0.3936 1.24 0.751 2.04 0.423 0.243 0.0817 1.088 1.53 0.948 2.46 PRS_PLINK_2.51188643150958e.06 FALSE 740.2 Osteoarthrosis, generalized Both 715 1405 14 musculoskeletal darkolivegreen 1405, 715 352, 183 351, 178 351, 179 351, 175 -0.0176 0.0473 0.709 0.1492 0.983 0.895 1.08 0.0096 0.138 0.944 0.02482 1.01 0.771 1.32 0.0468 0.138 0.734 0.1343 1.05 0.8 1.37 -0.00605 0.139 0.965 0.01532 0.994 0.757 1.31 PRS_PLINK_2.51188643150958e.06 FALSE 740.3 Osteoarthrosis involving more than one site, but not specified as generalized Both 169 419 14 musculoskeletal darkolivegreen 419, 169 105, 47 105, 38 104, 37 105, 47 -0.022 0.09 0.807 0.093 0.978 0.82 1.17 -0.16 0.266 0.547 0.2618 0.852 0.506 1.44 -0.18 0.266 0.499 0.302 0.835 0.496 1.41 0.0759 0.258 0.768 0.1145 1.08 0.651 1.79 PRS_PLINK_2.51188643150958e.06 FALSE 740.9 Osteoarthrosis NOS Both 4049 3251 14 musculoskeletal darkolivegreen 3251, 4049 813, 987 813, 1104 812, 984 813, 973 0.0111 0.0253 0.662 0.1794 1.01 0.962 1.06 0.109 0.0715 0.127 0.8967 1.12 0.97 1.28 -0.0271 0.0721 0.707 0.1504 0.973 0.845 1.12 0.013 0.0726 0.858 0.06672 1.01 0.879 1.17 PRS_PLINK_2.51188643150958e.06 FALSE 741 Symptoms and disorders of the joints Both 2592 4279 14 musculoskeletal darkolivegreen 4279, 2592 1069, 659 1070, 607 1069, 660 1070, 666 0.0279 0.0256 0.274 0.5615 1.03 0.978 1.08 -0.104 0.0727 0.153 0.8154 0.901 0.781 1.04 -0.000632 0.0715 0.993 0.003076 0.999 0.869 1.15 0.0344 0.0717 0.631 0.1997 1.03 0.899 1.19 PRS_PLINK_2.51188643150958e.06 FALSE 741.1 Ankylosis of joint Both 52 310 14 musculoskeletal darkolivegreen 310, 52 78, 13 77, 12 77, 15 78, 12 -0.115 0.136 0.399 0.3988 0.892 0.683 1.16 -0.117 0.443 0.791 0.1016 0.889 0.373 2.12 0.107 0.433 0.806 0.09373 1.11 0.476 2.6 0.0474 0.439 0.914 0.03898 1.05 0.443 2.48 PRS_PLINK_2.51188643150958e.06 FALSE 741.2 Stiffness of joint Both 364 1573 14 musculoskeletal darkolivegreen 1573, 364 394, 97 393, 69 393, 100 393, 98 0.00701 0.0578 0.904 0.04406 1.01 0.899 1.13 -0.358 0.175 0.0407 1.391 0.699 0.496 0.985 0.0381 0.16 0.812 0.09027 1.04 0.759 1.42 0.00564 0.162 0.972 0.01223 1.01 0.732 1.38 PRS_PLINK_2.51188643150958e.06 FALSE 741.3 Difficulty in walking Both 965 2895 14 musculoskeletal darkolivegreen 2895, 965 723, 268 724, 203 723, 242 724, 252 0.00769 0.0375 0.837 0.07713 1.01 0.936 1.08 -0.271 0.108 0.0123 1.91 0.763 0.617 0.943 -0.0831 0.104 0.426 0.3705 0.92 0.75 1.13 -0.0437 0.104 0.675 0.1709 0.957 0.78 1.17 PRS_PLINK_2.51188643150958e.06 FALSE 741.4 Joint effusions Both 873 2955 14 musculoskeletal darkolivegreen 2955, 873 738, 198 739, 217 738, 232 739, 226 0.035 0.0385 0.364 0.439 1.04 0.96 1.12 0.0604 0.112 0.591 0.2288 1.06 0.852 1.32 0.136 0.111 0.221 0.6547 1.15 0.921 1.42 0.143 0.111 0.199 0.7006 1.15 0.927 1.44 PRS_PLINK_2.51188643150958e.06 FALSE 741.5 Hemarthrosis Both 37 121 14 musculoskeletal darkolivegreen 121, 37 31, 9 30, 7 30, 8 30, 13 0.346 0.226 0.126 0.9009 1.41 0.908 2.2 -0.269 0.598 0.653 0.185 0.765 0.237 2.47 -0.012 0.604 0.984 0.006919 0.988 0.302 3.23 0.884 0.572 0.122 0.9121 2.42 0.788 7.43 PRS_PLINK_2.51188643150958e.06 TRUE 741.6 Villonodular synovitis Both 19 76 14 musculoskeletal darkolivegreen 76, 19 19, 4 19, 8 19, 7 19, 0 -0.0655 0.308 0.832 0.07995 0.937 0.512 1.71 0.51 0.735 0.488 0.3115 1.67 0.394 7.04 1.91 0.975 0.0497 1.304 6.78 1 45.8 -0.887 1.29 0.491 0.3088 0.412 0.033 5.14 PRS_PLINK_2.51188643150958e.06 TRUE 742 Derangement of joint, non-traumatic Both 1334 4036 14 musculoskeletal darkolivegreen 4036, 1334 1009, 358 1009, 318 1009, 313 1009, 345 0.00527 0.0316 0.868 0.06164 1.01 0.945 1.07 -0.13 0.0901 0.147 0.8314 0.878 0.736 1.05 -0.136 0.0901 0.133 0.8773 0.873 0.732 1.04 -0.0193 0.0889 0.829 0.08165 0.981 0.824 1.17 PRS_PLINK_2.51188643150958e.06 FALSE 742.1 Loose body in joint Both 30 153 14 musculoskeletal darkolivegreen 153, 30 39, 11 38, 4 38, 4 38, 11 -0.0457 0.232 0.844 0.07366 0.955 0.606 1.51 -0.92 0.592 0.121 0.9187 0.399 0.125 1.27 -0.942 0.602 0.117 0.931 0.39 0.12 1.27 0.108 0.478 0.821 0.08571 1.11 0.437 2.84 PRS_PLINK_2.51188643150958e.06 TRUE 742.2 Pathological, developmental or recurrent dislocation Both 51 244 14 musculoskeletal darkolivegreen 244, 51 61, 13 61, 15 61, 12 61, 11 -0.0413 0.155 0.79 0.1024 0.96 0.708 1.3 0.174 0.425 0.682 0.1665 1.19 0.518 2.74 -0.383 0.485 0.43 0.3667 0.682 0.263 1.76 -0.474 0.489 0.333 0.4781 0.623 0.239 1.62 PRS_PLINK_2.51188643150958e.06 FALSE 742.8 Articular cartilage disorder Both 51 269 14 musculoskeletal darkolivegreen 269, 51 68, 11 67, 18 67, 13 67, 9 -0.145 0.165 0.379 0.4209 0.865 0.626 1.2 0.319 0.425 0.454 0.3432 1.38 0.597 3.17 0.173 0.44 0.695 0.158 1.19 0.501 2.82 -0.175 0.472 0.712 0.1478 0.84 0.333 2.12 PRS_PLINK_2.51188643150958e.06 FALSE 742.9 Other derangement of joint Both 1275 3939 14 musculoskeletal darkolivegreen 3939, 1275 985, 339 985, 304 984, 300 985, 332 0.00672 0.0323 0.835 0.07833 1.01 0.945 1.07 -0.118 0.0919 0.2 0.6994 0.889 0.742 1.06 -0.124 0.0921 0.179 0.7461 0.884 0.738 1.06 -0.00307 0.0908 0.973 0.0119 0.997 0.834 1.19 PRS_PLINK_2.51188643150958e.06 FALSE 743 Osteoporosis, osteopenia and pathological fracture Both 2894 4512 14 musculoskeletal darkolivegreen 4512, 2894 1127, 703 1128, 744 1128, 721 1128, 726 0.0428 0.026 0.0996 1.002 1.04 0.992 1.1 0.0274 0.0732 0.709 0.1495 1.03 0.89 1.19 0.0276 0.0736 0.708 0.1502 1.03 0.89 1.19 0.0826 0.0735 0.261 0.5827 1.09 0.94 1.25 PRS_PLINK_2.51188643150958e.06 FALSE 743.1 Osteoporosis Both 1240 2592 14 musculoskeletal darkolivegreen 2592, 1240 648, 311 648, 314 648, 292 648, 323 0.0442 0.0387 0.254 0.5956 1.05 0.969 1.13 0.0203 0.105 0.846 0.07246 1.02 0.831 1.25 -0.0504 0.106 0.634 0.198 0.951 0.773 1.17 0.0983 0.104 0.343 0.4646 1.1 0.9 1.35 PRS_PLINK_2.51188643150958e.06 FALSE 743.11 Osteoporosis NOS Both 1217 2571 14 musculoskeletal darkolivegreen 2571, 1217 643, 304 643, 310 642, 286 643, 317 0.0474 0.0391 0.226 0.6465 1.05 0.971 1.13 0.043 0.106 0.684 0.1648 1.04 0.849 1.28 -0.0411 0.107 0.701 0.1545 0.96 0.778 1.18 0.11 0.105 0.292 0.5349 1.12 0.91 1.37 PRS_PLINK_2.51188643150958e.06 FALSE 743.12 Senile osteoporosis Both 295 683 14 musculoskeletal darkolivegreen 683, 295 171, 73 171, 74 170, 62 171, 86 0.064 0.0784 0.414 0.3831 1.07 0.914 1.24 0.00739 0.207 0.972 0.01255 1.01 0.672 1.51 -0.0738 0.211 0.727 0.1387 0.929 0.614 1.41 0.178 0.201 0.377 0.4232 1.19 0.805 1.77 PRS_PLINK_2.51188643150958e.06 FALSE 743.13 Other specified osteoporosis Both 149 400 14 musculoskeletal darkolivegreen 400, 149 100, 45 100, 32 100, 35 100, 37 0.0183 0.101 0.855 0.06781 1.02 0.836 1.24 -0.304 0.279 0.275 0.561 0.738 0.427 1.27 -0.28 0.274 0.307 0.5125 0.756 0.441 1.29 -0.154 0.271 0.569 0.2448 0.857 0.504 1.46 PRS_PLINK_2.51188643150958e.06 FALSE 743.2 Pathologic fracture Both 432 1316 14 musculoskeletal darkolivegreen 1316, 432 329, 122 329, 100 329, 90 329, 120 -0.00212 0.0558 0.97 0.01339 0.998 0.895 1.11 -0.208 0.159 0.192 0.7162 0.813 0.595 1.11 -0.271 0.164 0.0981 1.008 0.763 0.553 1.05 -0.0136 0.154 0.93 0.03159 0.987 0.73 1.33 PRS_PLINK_2.51188643150958e.06 FALSE 743.21 Pathologic fracture of vertebrae Both 202 562 14 musculoskeletal darkolivegreen 562, 202 141, 61 140, 45 140, 44 141, 52 -0.00718 0.0832 0.931 0.03098 0.993 0.843 1.17 -0.339 0.237 0.152 0.8173 0.712 0.448 1.13 -0.275 0.239 0.249 0.6035 0.76 0.476 1.21 -0.139 0.229 0.545 0.2634 0.871 0.556 1.36 PRS_PLINK_2.51188643150958e.06 FALSE 743.22 Pathologic fracture of femur Both 52 160 14 musculoskeletal darkolivegreen 160, 52 40, 15 40, 11 40, 15 40, 11 -0.0224 0.163 0.891 0.05034 0.978 0.71 1.35 -0.428 0.537 0.425 0.3715 0.652 0.228 1.87 0.0563 0.451 0.901 0.04542 1.06 0.437 2.56 -0.295 0.477 0.536 0.2707 0.745 0.293 1.9 PRS_PLINK_2.51188643150958e.06 FALSE 743.4 Stress fracture Both 146 582 14 musculoskeletal darkolivegreen 582, 146 146, 37 145, 29 145, 31 146, 49 0.108 0.101 0.284 0.5466 1.11 0.914 1.36 -0.323 0.276 0.242 0.6164 0.724 0.421 1.24 -0.267 0.283 0.346 0.4613 0.766 0.44 1.33 0.228 0.256 0.374 0.4277 1.26 0.761 2.07 PRS_PLINK_2.51188643150958e.06 FALSE 743.9 Osteopenia or other disorder of bone and cartilage Both 2398 4359 14 musculoskeletal darkolivegreen 4359, 2398 1089, 588 1090, 625 1089, 611 1090, 574 0.0289 0.0277 0.297 0.5269 1.03 0.975 1.09 0.0228 0.0778 0.769 0.1139 1.02 0.878 1.19 0.0461 0.0779 0.554 0.2567 1.05 0.899 1.22 0.0337 0.0787 0.668 0.175 1.03 0.886 1.21 PRS_PLINK_2.51188643150958e.06 FALSE 745 Pain in joint Both 5274 2177 14 musculoskeletal darkolivegreen 2177, 5274 545, 1291 544, 1330 544, 1381 544, 1271 0.0497 0.0256 0.0524 1.28 1.05 0.999 1.11 0.022 0.0738 0.765 0.1162 1.02 0.885 1.18 0.0835 0.0736 0.256 0.591 1.09 0.941 1.26 0.016 0.0743 0.829 0.0815 1.02 0.879 1.18 PRS_PLINK_2.51188643150958e.06 FALSE 747 Cardiac and circulatory congenital anomalies Both 601 3560 15 congenital anomalies mediumspringgreen 3560, 601 890, 144 890, 144 890, 155 890, 157 0.0138 0.0439 0.753 0.1231 1.01 0.93 1.1 -0.0114 0.127 0.928 0.03224 0.989 0.771 1.27 0.0698 0.125 0.577 0.2387 1.07 0.839 1.37 0.0842 0.125 0.502 0.2996 1.09 0.851 1.39 PRS_PLINK_2.51188643150958e.06 FALSE 747.1 Cardiac congenital anomalies Both 471 2810 15 congenital anomalies mediumspringgreen 2810, 471 703, 108 702, 114 702, 117 703, 131 0.0441 0.0505 0.383 0.417 1.05 0.947 1.15 0.0519 0.144 0.719 0.143 1.05 0.794 1.4 0.0855 0.144 0.552 0.2583 1.09 0.822 1.44 0.207 0.141 0.142 0.8486 1.23 0.933 1.62 PRS_PLINK_2.51188643150958e.06 FALSE 747.11 Cardiac shunt/ heart septal defect Both 171 1044 15 congenital anomalies mediumspringgreen 1044, 171 261, 42 261, 48 261, 37 261, 44 -0.0083 0.0831 0.92 0.03601 0.992 0.843 1.17 0.102 0.23 0.656 0.1833 1.11 0.706 1.74 -0.0677 0.241 0.778 0.1088 0.935 0.583 1.5 0.0883 0.236 0.708 0.15 1.09 0.688 1.73 PRS_PLINK_2.51188643150958e.06 FALSE 747.12 Valvular heart disease/ heart chambers Both 214 1195 15 congenital anomalies mediumspringgreen 1195, 214 299, 45 299, 52 298, 57 299, 59 0.0485 0.0759 0.523 0.2817 1.05 0.905 1.22 0.149 0.219 0.498 0.3031 1.16 0.755 1.78 0.234 0.216 0.278 0.5562 1.26 0.828 1.93 0.254 0.215 0.237 0.6247 1.29 0.846 1.97 PRS_PLINK_2.51188643150958e.06 FALSE 747.13 Congenital anomalies of great vessels Both 114 629 15 congenital anomalies mediumspringgreen 629, 114 158, 23 157, 26 157, 28 157, 37 0.116 0.106 0.272 0.5647 1.12 0.913 1.38 0.124 0.305 0.685 0.1643 1.13 0.623 2.06 0.233 0.303 0.444 0.353 1.26 0.696 2.29 0.485 0.294 0.0983 1.007 1.62 0.914 2.89 PRS_PLINK_2.51188643150958e.06 FALSE 747.2 Congenital anomalies of peripheral vascular system Both 137 784 15 congenital anomalies mediumspringgreen 784, 137 196, 33 196, 33 196, 38 196, 33 -0.0191 0.0942 0.839 0.07622 0.981 0.816 1.18 -0.0123 0.271 0.964 0.01598 0.988 0.581 1.68 0.145 0.258 0.576 0.2399 1.16 0.697 1.92 0.0267 0.267 0.921 0.03596 1.03 0.608 1.73 PRS_PLINK_2.51188643150958e.06 FALSE 748 Anomalies of respiratory system, congenital Both 18 195 15 congenital anomalies mediumspringgreen 195, 18 49, 9 49, 2 48, 3 49, 4 -0.145 0.219 0.509 0.2934 0.865 0.563 1.33 -1.46 0.718 0.0421 1.376 0.232 0.0568 0.949 -0.983 0.639 0.124 0.907 0.374 0.107 1.31 -0.795 0.624 0.203 0.6932 0.451 0.133 1.53 PRS_PLINK_2.51188643150958e.06 TRUE 749 Congenital anomalies of face and neck Both 112 770 15 congenital anomalies mediumspringgreen 770, 112 193, 27 192, 24 192, 41 193, 20 -0.0909 0.0954 0.341 0.4677 0.913 0.757 1.1 -0.096 0.296 0.746 0.1275 0.908 0.509 1.62 0.435 0.268 0.104 0.9813 1.54 0.914 2.61 -0.212 0.309 0.494 0.3066 0.809 0.441 1.48 PRS_PLINK_2.51188643150958e.06 FALSE 749.1 Cleft palate Both 5 103 15 congenital anomalies mediumspringgreen 103, 5 26, 3 26, 0 25, 2 26, 0 -0.512 0.366 0.162 0.7916 0.6 0.293 1.23 -2.83 1.67 0.0901 1.045 0.0591 0.00225 1.56 0.0548 0.921 0.953 0.02112 1.06 0.174 6.43 -3.21 1.76 0.0676 1.17 0.0402 0.00128 1.26 PRS_PLINK_2.51188643150958e.06 TRUE 749.2 Congenital anomalies of skull and face bones Both 22 132 15 congenital anomalies mediumspringgreen 132, 22 33, 5 33, 7 33, 8 33, 2 -0.373 0.245 0.128 0.8926 0.688 0.426 1.11 0.1 0.623 0.872 0.0595 1.11 0.326 3.75 0.614 0.616 0.32 0.4955 1.85 0.552 6.18 -0.75 0.819 0.36 0.4439 0.472 0.0949 2.35 PRS_PLINK_2.51188643150958e.06 TRUE 750 Digestive congenital anomalies Both 330 1424 15 congenital anomalies mediumspringgreen 1424, 330 356, 77 356, 87 356, 80 356, 86 -0.00325 0.0634 0.959 0.01811 0.997 0.88 1.13 0.129 0.174 0.457 0.3397 1.14 0.809 1.6 0.0328 0.177 0.853 0.06927 1.03 0.731 1.46 0.0684 0.175 0.696 0.1571 1.07 0.759 1.51 PRS_PLINK_2.51188643150958e.06 FALSE 750.1 Upper gastrointestinal congenital anomalies Both 95 590 15 congenital anomalies mediumspringgreen 590, 95 148, 25 147, 20 147, 22 148, 28 -0.0515 0.122 0.673 0.1721 0.95 0.748 1.21 -0.29 0.319 0.363 0.4405 0.748 0.4 1.4 -0.125 0.311 0.686 0.1634 0.882 0.48 1.62 0.0156 0.301 0.959 0.01833 1.02 0.563 1.83 PRS_PLINK_2.51188643150958e.06 FALSE 750.11 Esophageal atresia/tracheoesophageal fistula Both 37 186 15 congenital anomalies mediumspringgreen 186, 37 47, 8 46, 9 46, 10 47, 10 -0.143 0.189 0.449 0.3473 0.867 0.598 1.26 0.118 0.521 0.821 0.08549 1.12 0.405 3.12 0.325 0.537 0.545 0.2636 1.38 0.483 3.97 0.0629 0.53 0.906 0.0431 1.06 0.377 3.01 PRS_PLINK_2.51188643150958e.06 TRUE 750.13 Congenital anomalies of mouth/tongue Both 17 141 15 congenital anomalies mediumspringgreen 141, 17 36, 4 35, 4 35, 2 35, 7 -0.0399 0.243 0.869 0.06075 0.961 0.597 1.55 -0.358 0.711 0.615 0.2111 0.699 0.173 2.82 -0.301 0.866 0.729 0.1375 0.74 0.136 4.04 0.409 0.662 0.536 0.2704 1.51 0.411 5.51 PRS_PLINK_2.51188643150958e.06 TRUE 750.14 Congenital anomalies of esophagus Both 34 213 15 congenital anomalies mediumspringgreen 213, 34 54, 6 53, 9 53, 10 53, 9 0.0456 0.187 0.807 0.09287 1.05 0.725 1.51 0.542 0.571 0.342 0.4664 1.72 0.562 5.26 0.363 0.534 0.496 0.3046 1.44 0.505 4.09 0.177 0.561 0.753 0.1235 1.19 0.397 3.59 PRS_PLINK_2.51188643150958e.06 TRUE 750.15 Congenital anomalies of stomach Both 15 106 15 congenital anomalies mediumspringgreen 106, 15 27, 4 26, 0 26, 3 27, 8 0.533 0.398 0.181 0.7428 1.7 0.781 3.72 -2.04 1.22 0.0936 1.029 0.13 0.0119 1.41 0.084 0.818 0.918 0.03704 1.09 0.219 5.41 0.548 0.669 0.413 0.3844 1.73 0.466 6.43 PRS_PLINK_2.51188643150958e.06 TRUE 750.2 Lower gastrointestinal congenital anomalies Both 237 865 15 congenital anomalies mediumspringgreen 865, 237 217, 52 216, 62 216, 60 216, 63 0.0412 0.0745 0.58 0.2364 1.04 0.9 1.21 0.211 0.214 0.324 0.4899 1.23 0.812 1.88 0.163 0.214 0.447 0.3499 1.18 0.774 1.79 0.215 0.213 0.313 0.5044 1.24 0.816 1.88 PRS_PLINK_2.51188643150958e.06 FALSE 750.21 Congenital anomalies of intestine Both 143 520 15 congenital anomalies mediumspringgreen 520, 143 130, 36 130, 35 130, 33 130, 39 0.0121 0.101 0.905 0.0434 1.01 0.83 1.23 0.0487 0.271 0.857 0.06693 1.05 0.618 1.78 -0.00363 0.278 0.99 0.004552 0.996 0.578 1.72 0.0669 0.269 0.803 0.0951 1.07 0.631 1.81 PRS_PLINK_2.51188643150958e.06 FALSE 750.22 Congenital anomaly of gallbladder, bile ducts, liver, pancreas Both 97 367 15 congenital anomalies mediumspringgreen 367, 97 92, 20 92, 27 91, 28 92, 22 0.0232 0.106 0.827 0.08244 1.02 0.831 1.26 0.331 0.332 0.319 0.4959 1.39 0.726 2.67 0.352 0.33 0.287 0.5424 1.42 0.744 2.72 0.0659 0.349 0.85 0.07038 1.07 0.539 2.12 PRS_PLINK_2.51188643150958e.06 FALSE 751 Genitourinary congenital anomalies Both 539 3039 15 congenital anomalies mediumspringgreen 3039, 539 759, 116 760, 144 759, 140 760, 139 0.0784 0.0482 0.104 0.9835 1.08 0.984 1.19 0.216 0.135 0.109 0.9637 1.24 0.953 1.62 0.206 0.136 0.13 0.8854 1.23 0.941 1.6 0.21 0.136 0.123 0.9088 1.23 0.944 1.61 PRS_PLINK_2.51188643150958e.06 FALSE 751.1 Congenital anomalies of genital organs Both 159 843 15 congenital anomalies mediumspringgreen 843, 159 211, 31 211, 45 210, 39 211, 44 0.139 0.0978 0.154 0.8125 1.15 0.949 1.39 0.373 0.253 0.141 0.85 1.45 0.884 2.38 0.202 0.261 0.437 0.359 1.22 0.735 2.04 0.35 0.253 0.167 0.7772 1.42 0.864 2.33 PRS_PLINK_2.51188643150958e.06 FALSE 751.11 Congenital anomalies of female genital organs Female 129 645 15 congenital anomalies mediumspringgreen 645, 129 162, 24 161, 38 161, 30 161, 37 0.132 0.107 0.214 0.6691 1.14 0.926 1.41 0.459 0.286 0.108 0.9662 1.58 0.904 2.77 0.172 0.295 0.558 0.2532 1.19 0.667 2.12 0.454 0.283 0.109 0.9629 1.57 0.904 2.74 PRS_PLINK_2.51188643150958e.06 FALSE 751.12 Congenital anomalies of male genital organs Male 22 172 15 congenital anomalies mediumspringgreen 172, 22 43, 7 43, 2 43, 10 43, 3 0.0613 0.25 0.806 0.09367 1.06 0.652 1.73 -1.15 0.725 0.113 0.9461 0.317 0.0766 1.31 0.395 0.531 0.457 0.3402 1.48 0.524 4.2 -0.871 0.68 0.2 0.6988 0.419 0.11 1.59 PRS_PLINK_2.51188643150958e.06 TRUE 751.2 Congenital anomalies of urinary system Both 386 2159 15 congenital anomalies mediumspringgreen 2159, 386 539, 90 540, 93 539, 107 540, 96 0.0164 0.0564 0.771 0.113 1.02 0.91 1.14 0.0262 0.16 0.87 0.06044 1.03 0.75 1.4 0.185 0.155 0.233 0.6324 1.2 0.888 1.63 0.0568 0.159 0.721 0.1422 1.06 0.775 1.45 PRS_PLINK_2.51188643150958e.06 FALSE 751.21 Cystic kidney disease Both 291 1572 15 congenital anomalies mediumspringgreen 1572, 291 392, 61 393, 74 393, 87 393, 69 0.0474 0.0648 0.465 0.3325 1.05 0.923 1.19 0.183 0.188 0.331 0.4802 1.2 0.831 1.74 0.366 0.182 0.0442 1.355 1.44 1.01 2.06 0.104 0.189 0.582 0.2349 1.11 0.766 1.61 PRS_PLINK_2.51188643150958e.06 FALSE 751.22 Other specified congenital anomalies of kidney Both 77 421 15 congenital anomalies mediumspringgreen 421, 77 106, 19 105, 16 105, 20 105, 22 0.0551 0.131 0.674 0.1714 1.06 0.817 1.37 -0.156 0.367 0.67 0.1737 0.856 0.417 1.75 0.105 0.351 0.766 0.116 1.11 0.558 2.21 0.11 0.351 0.753 0.123 1.12 0.561 2.22 PRS_PLINK_2.51188643150958e.06 FALSE 751.3 Obstructive genitourinary defect Both 34 235 15 congenital anomalies mediumspringgreen 235, 34 59, 8 59, 6 58, 5 59, 15 0.542 0.242 0.0254 1.595 1.72 1.07 2.77 -0.138 0.545 0.8 0.09672 0.871 0.299 2.54 -0.717 0.611 0.24 0.6195 0.488 0.148 1.62 0.7 0.49 0.153 0.8147 2.01 0.771 5.26 PRS_PLINK_2.51188643150958e.06 TRUE 752 Nervous system congenital anomalies Both 303 1831 15 congenital anomalies mediumspringgreen 1831, 303 458, 83 458, 77 457, 70 458, 73 -0.0157 0.06 0.793 0.1005 0.984 0.875 1.11 -0.114 0.172 0.507 0.2947 0.892 0.637 1.25 -0.174 0.175 0.32 0.4955 0.84 0.597 1.18 -0.14 0.174 0.421 0.3761 0.869 0.619 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 752.1 Neural tube defects Both 236 1518 15 congenital anomalies mediumspringgreen 1518, 236 380, 74 379, 53 379, 53 380, 56 -0.0605 0.0665 0.362 0.4407 0.941 0.826 1.07 -0.364 0.194 0.0603 1.22 0.695 0.475 1.02 -0.352 0.193 0.0686 1.163 0.703 0.481 1.03 -0.289 0.191 0.131 0.8822 0.749 0.515 1.09 PRS_PLINK_2.51188643150958e.06 FALSE 752.11 Spina bifida Both 43 268 15 congenital anomalies mediumspringgreen 268, 43 67, 11 67, 13 67, 12 67, 7 -0.0708 0.151 0.639 0.1948 0.932 0.693 1.25 0.204 0.446 0.647 0.189 1.23 0.511 2.94 0.0449 0.44 0.919 0.03678 1.05 0.441 2.48 -0.356 0.523 0.496 0.3042 0.701 0.251 1.95 PRS_PLINK_2.51188643150958e.06 TRUE 752.2 Other specified congenital anomalies of nervous system Both 69 337 15 congenital anomalies mediumspringgreen 337, 69 85, 14 84, 22 84, 14 84, 19 0.112 0.14 0.423 0.3732 1.12 0.85 1.47 0.727 0.417 0.0814 1.09 2.07 0.913 4.68 0.189 0.418 0.651 0.1867 1.21 0.533 2.74 0.462 0.396 0.243 0.6149 1.59 0.731 3.45 PRS_PLINK_2.51188643150958e.06 FALSE 753 Congenital anomalies of the eye Both 61 323 15 congenital anomalies mediumspringgreen 323, 61 81, 17 81, 15 80, 19 81, 10 -0.23 0.131 0.0791 1.102 0.794 0.615 1.03 -0.162 0.402 0.687 0.1631 0.85 0.387 1.87 0.0367 0.373 0.922 0.03544 1.04 0.499 2.16 -0.682 0.444 0.124 0.9054 0.506 0.212 1.21 PRS_PLINK_2.51188643150958e.06 FALSE 753.1 Congenital cataract and lens anomalies Both 17 91 15 congenital anomalies mediumspringgreen 91, 17 23, 4 23, 7 22, 5 23, 1 -0.452 0.275 0.1 0.9987 0.636 0.371 1.09 0.373 0.716 0.603 0.2198 1.45 0.357 5.91 0.249 0.707 0.725 0.1398 1.28 0.321 5.13 -0.613 0.914 0.502 0.2994 0.541 0.0903 3.25 PRS_PLINK_2.51188643150958e.06 TRUE 753.2 Congenital anomalies of posterior segment of eye Both 19 84 15 congenital anomalies mediumspringgreen 84, 19 21, 7 21, 3 21, 8 21, 1 -0.16 0.239 0.504 0.2973 0.852 0.534 1.36 -0.608 0.837 0.468 0.3301 0.545 0.106 2.81 -0.23 0.643 0.72 0.1424 0.794 0.225 2.8 -0.891 0.967 0.357 0.4477 0.41 0.0617 2.73 PRS_PLINK_2.51188643150958e.06 TRUE 754 Congenital musculoskeletal deformities of spine Both 359 1962 15 congenital anomalies mediumspringgreen 1962, 359 491, 109 490, 72 490, 87 491, 91 -0.0328 0.0568 0.563 0.2496 0.968 0.866 1.08 -0.413 0.165 0.012 1.92 0.662 0.479 0.913 -0.222 0.157 0.157 0.8036 0.801 0.588 1.09 -0.181 0.156 0.245 0.6104 0.834 0.614 1.13 PRS_PLINK_2.51188643150958e.06 FALSE 754.1 Lumbosacral spondylolysis, congenital Both 45 238 15 congenital anomalies mediumspringgreen 238, 45 60, 9 59, 9 59, 14 60, 13 0.258 0.193 0.18 0.7436 1.29 0.887 1.89 -0.0127 0.499 0.98 0.008908 0.987 0.371 2.63 0.536 0.477 0.261 0.5833 1.71 0.671 4.35 0.095 0.497 0.848 0.07144 1.1 0.415 2.91 PRS_PLINK_2.51188643150958e.06 TRUE 754.2 Spondylolisthesis, congenital Both 161 967 15 congenital anomalies mediumspringgreen 967, 161 242, 55 242, 28 241, 37 242, 41 -0.0533 0.0844 0.528 0.2776 0.948 0.803 1.12 -0.682 0.247 0.00578 2.238 0.506 0.311 0.821 -0.395 0.23 0.0863 1.064 0.673 0.429 1.06 -0.263 0.227 0.247 0.6077 0.769 0.493 1.2 PRS_PLINK_2.51188643150958e.06 FALSE 755 Congenital anomalies of limbs Both 191 1091 15 congenital anomalies mediumspringgreen 1091, 191 273, 54 273, 53 272, 43 273, 41 -0.116 0.0761 0.128 0.894 0.891 0.767 1.03 -0.0405 0.214 0.85 0.07064 0.96 0.631 1.46 -0.197 0.222 0.377 0.4239 0.822 0.531 1.27 -0.207 0.227 0.363 0.4403 0.813 0.521 1.27 PRS_PLINK_2.51188643150958e.06 FALSE 755.1 Congenital deformities of feet Both 107 563 15 congenital anomalies mediumspringgreen 563, 107 141, 26 141, 32 140, 23 141, 26 -0.0595 0.0968 0.539 0.2682 0.942 0.779 1.14 0.126 0.29 0.663 0.1784 1.13 0.643 2 -0.0409 0.309 0.895 0.04832 0.96 0.524 1.76 0.0135 0.306 0.965 0.01559 1.01 0.556 1.85 PRS_PLINK_2.51188643150958e.06 FALSE 755.4 Congenital anomalies of upper limb, including shoulder girdle Both 16 105 15 congenital anomalies mediumspringgreen 105, 16 27, 6 26, 4 26, 3 26, 3 -0.269 0.296 0.365 0.4378 0.764 0.428 1.37 -0.364 0.689 0.597 0.224 0.695 0.18 2.68 -0.514 0.733 0.483 0.3158 0.598 0.142 2.52 -1.05 0.804 0.19 0.7206 0.349 0.0721 1.69 PRS_PLINK_2.51188643150958e.06 TRUE 755.6 Other congenital anomalies of lower limb, including pelvic girdle Both 67 427 15 congenital anomalies mediumspringgreen 427, 67 107, 22 107, 17 106, 14 107, 14 -0.112 0.13 0.391 0.4083 0.894 0.693 1.15 -0.162 0.356 0.648 0.1884 0.85 0.423 1.71 -0.388 0.369 0.293 0.5335 0.679 0.33 1.4 -0.243 0.374 0.516 0.2871 0.785 0.377 1.63 PRS_PLINK_2.51188643150958e.06 FALSE 755.61 Congenital hip dysplasia and deformity Both 34 249 15 congenital anomalies mediumspringgreen 249, 34 63, 12 62, 5 62, 6 62, 11 0.0791 0.193 0.683 0.1658 1.08 0.741 1.58 -0.663 0.544 0.223 0.6516 0.515 0.178 1.5 -0.617 0.531 0.245 0.6105 0.54 0.191 1.53 0.351 0.503 0.485 0.3144 1.42 0.53 3.81 PRS_PLINK_2.51188643150958e.06 TRUE 756 Other congenital musculoskeletal anomalies Both 406 2014 15 congenital anomalies mediumspringgreen 2014, 406 504, 113 503, 71 503, 110 504, 112 0.0531 0.0577 0.357 0.4472 1.05 0.942 1.18 -0.47 0.164 0.00424 2.373 0.625 0.453 0.863 -0.0057 0.148 0.969 0.01351 0.994 0.743 1.33 0.0257 0.149 0.863 0.06401 1.03 0.767 1.37 PRS_PLINK_2.51188643150958e.06 FALSE 756.1 Congenital anomalies of abdominal wall; diaphram Both 24 108 15 congenital anomalies mediumspringgreen 108, 24 27, 3 27, 5 27, 7 27, 9 0.272 0.254 0.284 0.5467 1.31 0.798 2.16 1.02 0.905 0.262 0.5822 2.76 0.469 16.2 0.596 0.757 0.431 0.3651 1.81 0.411 8 1.34 0.77 0.0813 1.09 3.82 0.846 17.3 PRS_PLINK_2.51188643150958e.06 TRUE 756.2 Pectus and other congenital anomalies of ribs/sternum Both 11 66 15 congenital anomalies mediumspringgreen 66, 11 17, 3 16, 4 16, 3 17, 1 -0.536 0.357 0.133 0.8767 0.585 0.291 1.18 0.768 0.943 0.415 0.3815 2.16 0.339 13.7 0.122 1.05 0.908 0.04189 1.13 0.143 8.89 -0.0968 1.26 0.939 0.02734 0.908 0.0762 10.8 PRS_PLINK_2.51188643150958e.06 TRUE 756.3 Congenital anomalies of muscle, tendon, fascia, and connective tissue Both 102 447 15 congenital anomalies mediumspringgreen 447, 102 112, 29 112, 23 111, 22 112, 28 -0.0278 0.118 0.813 0.08969 0.973 0.772 1.23 -0.217 0.318 0.495 0.3053 0.805 0.432 1.5 -0.264 0.309 0.393 0.4058 0.768 0.419 1.41 -0.0216 0.298 0.942 0.0259 0.979 0.546 1.75 PRS_PLINK_2.51188643150958e.06 FALSE 756.5 Congenital osteodystrophies Both 293 1535 15 congenital anomalies mediumspringgreen 1535, 293 384, 82 384, 54 383, 77 384, 80 0.047 0.0669 0.482 0.3173 1.05 0.919 1.19 -0.411 0.191 0.0315 1.502 0.663 0.456 0.964 -0.0512 0.175 0.769 0.1138 0.95 0.675 1.34 0.0206 0.175 0.906 0.04269 1.02 0.725 1.44 PRS_PLINK_2.51188643150958e.06 FALSE 757 Congenital anomalies of the integument Both 106 673 15 congenital anomalies mediumspringgreen 673, 106 169, 24 168, 28 168, 31 168, 23 -0.0224 0.105 0.831 0.08065 0.978 0.796 1.2 0.0976 0.304 0.749 0.1258 1.1 0.607 2 0.357 0.297 0.23 0.6388 1.43 0.798 2.56 -0.0687 0.31 0.825 0.08364 0.934 0.508 1.72 PRS_PLINK_2.51188643150958e.06 FALSE 758 Chromosomal anomalies and genetic disorders Both 52 290 15 congenital anomalies mediumspringgreen 290, 52 73, 17 72, 6 72, 13 73, 16 0.0728 0.154 0.636 0.1967 1.08 0.796 1.45 -1.08 0.492 0.0279 1.555 0.339 0.129 0.889 -0.166 0.431 0.7 0.1548 0.847 0.364 1.97 -0.172 0.392 0.66 0.1805 0.842 0.391 1.81 PRS_PLINK_2.51188643150958e.06 FALSE 758.1 Chromosomal anomalies Both 37 228 15 congenital anomalies mediumspringgreen 228, 37 57, 10 57, 7 57, 9 57, 11 -0.0084 0.156 0.957 0.01911 0.992 0.731 1.35 -0.492 0.554 0.375 0.4261 0.612 0.206 1.81 -0.167 0.553 0.763 0.1177 0.846 0.286 2.5 -0.14 0.491 0.775 0.1109 0.869 0.332 2.27 PRS_PLINK_2.51188643150958e.06 TRUE 759 Other and unspecified congenital anomalies Both 135 854 15 congenital anomalies mediumspringgreen 854, 135 214, 28 213, 33 213, 34 214, 40 0.16 0.0993 0.107 0.9695 1.17 0.966 1.43 0.106 0.274 0.7 0.1551 1.11 0.649 1.9 0.255 0.273 0.35 0.456 1.29 0.756 2.2 0.274 0.264 0.3 0.5232 1.32 0.783 2.21 PRS_PLINK_2.51188643150958e.06 FALSE 759.1 Anomalies of endocrine glands, congenital Both 15 122 15 congenital anomalies mediumspringgreen 122, 15 31, 4 30, 3 30, 5 31, 3 -0.0666 0.28 0.812 0.09035 0.936 0.54 1.62 -0.301 0.929 0.746 0.1273 0.74 0.12 4.57 0.753 0.735 0.306 0.5143 2.12 0.502 8.97 -0.699 0.892 0.434 0.363 0.497 0.0865 2.86 PRS_PLINK_2.51188643150958e.06 TRUE 760 Back pain Both 4723 2729 17 symptoms purple 2729, 4723 682, 1150 682, 1238 682, 1151 682, 1184 0.0412 0.0242 0.0889 1.051 1.04 0.994 1.09 0.0691 0.069 0.317 0.4991 1.07 0.936 1.23 0.00175 0.0695 0.98 0.008814 1 0.874 1.15 0.0436 0.0695 0.531 0.2751 1.04 0.911 1.2 PRS_PLINK_2.51188643150958e.06 FALSE 761 Cervicalgia Both 2345 5068 17 symptoms purple 5068, 2345 1266, 612 1267, 588 1267, 592 1267, 553 -0.00895 0.0252 0.722 0.1413 0.991 0.943 1.04 -0.0443 0.0708 0.532 0.274 0.957 0.833 1.1 -0.0297 0.0707 0.674 0.1712 0.971 0.845 1.11 -0.0887 0.0717 0.216 0.665 0.915 0.795 1.05 PRS_PLINK_2.51188643150958e.06 FALSE 763 Thoracic or lumbosacral neuritis or radiculitis, unspecified Both 1292 4239 17 symptoms purple 4239, 1292 1059, 315 1060, 343 1059, 311 1060, 323 0.0328 0.0326 0.314 0.5034 1.03 0.969 1.1 0.091 0.0908 0.316 0.5001 1.1 0.917 1.31 0.00762 0.0919 0.934 0.02969 1.01 0.842 1.21 0.0569 0.0916 0.535 0.2719 1.06 0.885 1.27 PRS_PLINK_2.51188643150958e.06 FALSE 764 Sciatica Both 1296 4216 17 symptoms purple 4216, 1296 1054, 308 1054, 329 1054, 313 1054, 346 0.0493 0.0326 0.131 0.8825 1.05 0.985 1.12 0.0718 0.0913 0.431 0.3654 1.07 0.899 1.28 0.0289 0.0922 0.754 0.1225 1.03 0.859 1.23 0.131 0.0906 0.148 0.8292 1.14 0.954 1.36 PRS_PLINK_2.51188643150958e.06 FALSE 765 Cervical radiculitis Both 624 2452 17 symptoms purple 2452, 624 613, 162 613, 171 613, 139 613, 152 -0.000452 0.0452 0.992 0.003477 1 0.915 1.09 0.053 0.125 0.671 0.1735 1.05 0.826 1.35 -0.159 0.13 0.22 0.6584 0.853 0.662 1.1 -0.0515 0.127 0.685 0.1641 0.95 0.74 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 766 Neuralgia, neuritis, and radiculitis NOS Both 1728 4727 17 symptoms purple 4727, 1728 1181, 408 1182, 466 1181, 422 1182, 432 0.032 0.0288 0.267 0.5742 1.03 0.976 1.09 0.129 0.0803 0.109 0.9611 1.14 0.972 1.33 0.047 0.0814 0.564 0.2489 1.05 0.894 1.23 0.0702 0.0814 0.388 0.411 1.07 0.915 1.26 PRS_PLINK_2.51188643150958e.06 FALSE 767 Cervicocranial/Cervicobrachial syndrome Both 67 167 17 symptoms purple 167, 67 42, 25 42, 15 41, 7 42, 20 -0.117 0.127 0.358 0.4467 0.89 0.694 1.14 -0.517 0.415 0.213 0.6706 0.597 0.264 1.35 -1.02 0.48 0.0341 1.467 0.362 0.141 0.927 -0.28 0.398 0.482 0.3174 0.756 0.346 1.65 PRS_PLINK_2.51188643150958e.06 FALSE 769 Nonallopathic lesions NEC Both 459 1951 17 symptoms purple 1951, 459 487, 107 488, 126 487, 123 488, 103 -0.0427 0.0507 0.4 0.3982 0.958 0.868 1.06 0.169 0.147 0.25 0.6018 1.18 0.888 1.58 0.186 0.149 0.21 0.6776 1.21 0.9 1.61 -0.0247 0.153 0.871 0.05977 0.976 0.723 1.32 PRS_PLINK_2.51188643150958e.06 FALSE 770 Myalgia and myositis unspecified Both 2022 4695 17 symptoms purple 4695, 2022 1173, 542 1174, 499 1173, 476 1174, 505 -0.0267 0.0268 0.318 0.4973 0.974 0.924 1.03 -0.0879 0.0751 0.241 0.6171 0.916 0.791 1.06 -0.136 0.0759 0.0736 1.133 0.873 0.752 1.01 -0.0634 0.0751 0.399 0.3994 0.939 0.81 1.09 PRS_PLINK_2.51188643150958e.06 FALSE 771 Musculoskeletal symptoms referable to limbs Both 1683 4089 17 symptoms purple 4089, 1683 1022, 441 1022, 410 1022, 413 1022, 419 0.0056 0.0297 0.851 0.0703 1.01 0.949 1.07 -0.0779 0.0827 0.346 0.4611 0.925 0.787 1.09 -0.0511 0.0826 0.536 0.2709 0.95 0.808 1.12 -0.048 0.0825 0.56 0.2516 0.953 0.811 1.12 PRS_PLINK_2.51188643150958e.06 FALSE 771.1 Swelling of limb Both 2165 4088 17 symptoms purple 4088, 2165 1021, 569 1022, 537 1022, 552 1022, 507 -0.031 0.027 0.251 0.6004 0.969 0.92 1.02 -0.0739 0.0762 0.332 0.4784 0.929 0.8 1.08 -0.0265 0.0757 0.727 0.1386 0.974 0.84 1.13 -0.105 0.0766 0.172 0.7644 0.901 0.775 1.05 PRS_PLINK_2.51188643150958e.06 FALSE 771.2 Cramp of limb Both 504 1418 17 symptoms purple 1418, 504 355, 139 354, 112 354, 136 355, 117 -0.04 0.0541 0.459 0.338 0.961 0.864 1.07 -0.195 0.149 0.19 0.7222 0.823 0.614 1.1 -0.00199 0.144 0.989 0.004807 0.998 0.752 1.32 -0.145 0.148 0.328 0.4845 0.865 0.647 1.16 PRS_PLINK_2.51188643150958e.06 FALSE 772 Symptoms of the muscles Both 706 2820 17 symptoms purple 2820, 706 704, 190 705, 179 705, 173 705, 164 -0.00724 0.0418 0.863 0.0642 0.993 0.915 1.08 -0.0474 0.118 0.688 0.1625 0.954 0.757 1.2 -0.0891 0.119 0.452 0.3444 0.915 0.725 1.15 -0.13 0.12 0.279 0.5549 0.878 0.694 1.11 PRS_PLINK_2.51188643150958e.06 FALSE 772.1 Muscular wasting and disuse atrophy Both 138 509 17 symptoms purple 509, 138 127, 43 127, 25 127, 41 127, 29 -0.0249 0.09 0.782 0.1065 0.975 0.818 1.16 -0.501 0.282 0.0755 1.122 0.606 0.349 1.05 -0.0445 0.258 0.863 0.06403 0.956 0.577 1.59 -0.415 0.277 0.133 0.8755 0.66 0.384 1.14 PRS_PLINK_2.51188643150958e.06 FALSE 772.2 Spasm of muscle Both 853 3090 17 symptoms purple 3090, 853 773, 204 772, 219 772, 227 773, 203 0.0194 0.0392 0.621 0.207 1.02 0.944 1.1 0.065 0.111 0.557 0.2541 1.07 0.859 1.33 0.124 0.11 0.258 0.588 1.13 0.913 1.41 0.00873 0.112 0.938 0.02785 1.01 0.81 1.26 PRS_PLINK_2.51188643150958e.06 FALSE 772.3 Muscle weakness Both 1178 3828 17 symptoms purple 3828, 1178 956, 329 957, 266 957, 295 957, 288 -0.00923 0.0333 0.782 0.1068 0.991 0.928 1.06 -0.208 0.0946 0.0282 1.55 0.812 0.675 0.978 -0.0972 0.0929 0.296 0.5293 0.907 0.756 1.09 -0.108 0.0935 0.246 0.6083 0.897 0.747 1.08 PRS_PLINK_2.51188643150958e.06 FALSE 772.4 Rhabdomyolysis Both 61 217 17 symptoms purple 217, 61 55, 17 54, 13 54, 17 54, 14 0.0559 0.153 0.715 0.146 1.06 0.784 1.43 -0.246 0.423 0.561 0.2512 0.782 0.341 1.79 0.116 0.416 0.781 0.1073 1.12 0.497 2.54 -0.13 0.433 0.764 0.117 0.878 0.376 2.05 PRS_PLINK_2.51188643150958e.06 FALSE 772.6 Facial weakness Both 178 661 17 symptoms purple 661, 178 166, 51 165, 36 165, 48 165, 43 -0.0279 0.0845 0.741 0.1303 0.972 0.824 1.15 -0.345 0.245 0.159 0.7976 0.708 0.438 1.15 -0.0476 0.23 0.836 0.07761 0.954 0.607 1.5 -0.116 0.238 0.626 0.2037 0.89 0.558 1.42 PRS_PLINK_2.51188643150958e.06 FALSE 780 Hypothermia/Chills Both 225 792 17 symptoms purple 792, 225 198, 63 198, 44 198, 57 198, 61 -0.116 0.0725 0.108 0.9656 0.89 0.772 1.03 -0.351 0.221 0.113 0.9487 0.704 0.456 1.09 -0.126 0.211 0.551 0.2589 0.882 0.583 1.33 -0.0404 0.208 0.846 0.07257 0.96 0.639 1.44 PRS_PLINK_2.51188643150958e.06 FALSE 781 Symptoms involving nervous and musculoskeletal systems Both 1199 3965 17 symptoms purple 3965, 1199 991, 314 991, 298 991, 294 991, 293 0.00632 0.0333 0.85 0.07074 1.01 0.943 1.07 -0.0532 0.093 0.567 0.2463 0.948 0.79 1.14 -0.0697 0.0934 0.456 0.3413 0.933 0.777 1.12 -0.0713 0.0934 0.445 0.3512 0.931 0.775 1.12 PRS_PLINK_2.51188643150958e.06 FALSE 781.1 Loss of height Both 50 221 17 symptoms purple 221, 50 56, 6 55, 16 55, 15 55, 13 0.297 0.198 0.133 0.8755 1.35 0.913 1.98 0.923 0.517 0.0742 1.129 2.52 0.914 6.93 0.92 0.531 0.0831 1.08 2.51 0.887 7.1 0.642 0.532 0.227 0.644 1.9 0.67 5.39 PRS_PLINK_2.51188643150958e.06 TRUE 781.2 Abnormal posture Both 20 73 17 symptoms purple 73, 20 19, 8 18, 6 18, 4 18, 2 -0.2 0.268 0.455 0.3422 0.819 0.485 1.38 -0.574 0.713 0.421 0.3761 0.563 0.139 2.28 -0.899 0.836 0.282 0.5497 0.407 0.079 2.09 -0.612 0.928 0.51 0.2926 0.542 0.0879 3.35 PRS_PLINK_2.51188643150958e.06 TRUE 782.3 Edema Both 2338 4684 17 symptoms purple 4684, 2338 1170, 562 1171, 588 1171, 596 1171, 592 0.0345 0.026 0.185 0.7329 1.04 0.984 1.09 0.0362 0.0733 0.622 0.2063 1.04 0.898 1.2 0.0725 0.0735 0.324 0.4893 1.08 0.931 1.24 0.0683 0.0737 0.354 0.4508 1.07 0.927 1.24 PRS_PLINK_2.51188643150958e.06 FALSE 782.6 Pallor and flushing Both 288 1289 17 symptoms purple 1289, 288 323, 65 322, 87 322, 71 322, 65 -0.0374 0.0634 0.555 0.2559 0.963 0.851 1.09 0.262 0.182 0.151 0.8207 1.3 0.909 1.86 0.0774 0.19 0.683 0.1655 1.08 0.745 1.57 0.0133 0.193 0.945 0.02454 1.01 0.694 1.48 PRS_PLINK_2.51188643150958e.06 FALSE 783 Fever of unknown origin Both 2075 5320 17 symptoms purple 5320, 2075 1329, 491 1330, 533 1330, 536 1330, 515 0.0286 0.0262 0.275 0.5613 1.03 0.978 1.08 0.0848 0.0739 0.251 0.6003 1.09 0.942 1.26 0.0875 0.0738 0.236 0.6275 1.09 0.944 1.26 0.0489 0.0745 0.512 0.2909 1.05 0.907 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 783.1 Postprocedural fever Both 78 367 17 symptoms purple 367, 78 92, 20 92, 19 91, 21 92, 18 -0.07 0.123 0.568 0.2454 0.932 0.733 1.19 -0.0631 0.351 0.857 0.06679 0.939 0.472 1.87 0.079 0.347 0.82 0.0862 1.08 0.548 2.14 -0.0952 0.358 0.79 0.1023 0.909 0.451 1.83 PRS_PLINK_2.51188643150958e.06 FALSE 785 Abdominal pain Both 4971 2479 17 symptoms purple 2479, 4971 620, 1153 620, 1262 619, 1309 620, 1246 0.0408 0.0247 0.0987 1.005 1.04 0.992 1.09 0.0948 0.0706 0.18 0.7455 1.1 0.957 1.26 0.145 0.0708 0.0408 1.389 1.16 1.01 1.33 0.0967 0.0714 0.175 0.7563 1.1 0.958 1.27 PRS_PLINK_2.51188643150958e.06 FALSE 788 Syncope and collapse Both 1491 5207 17 symptoms purple 5207, 1491 1301, 364 1302, 357 1301, 391 1302, 379 0.0436 0.0299 0.145 0.8372 1.04 0.985 1.11 -0.0151 0.0846 0.858 0.06631 0.985 0.835 1.16 0.083 0.0832 0.319 0.4964 1.09 0.923 1.28 0.0459 0.0838 0.584 0.2339 1.05 0.888 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 789 Nausea and vomiting Both 3269 4166 17 symptoms purple 4166, 3269 1041, 815 1041, 828 1041, 840 1042, 786 0.00141 0.0238 0.953 0.02099 1 0.956 1.05 0.00338 0.0673 0.96 0.01775 1 0.879 1.14 0.0258 0.0671 0.7 0.1547 1.03 0.9 1.17 -0.0481 0.068 0.48 0.3189 0.953 0.834 1.09 PRS_PLINK_2.51188643150958e.06 FALSE 789.1 Persistent vomiting Both 335 945 17 symptoms purple 945, 335 237, 90 236, 72 236, 80 236, 93 0.0744 0.0658 0.258 0.5877 1.08 0.947 1.23 -0.266 0.188 0.157 0.8035 0.767 0.531 1.11 -0.177 0.185 0.339 0.4692 0.838 0.584 1.2 -0.0128 0.18 0.944 0.02523 0.987 0.693 1.41 PRS_PLINK_2.51188643150958e.06 FALSE 790 Nonspecific findings on examination of blood Both 1029 2729 17 symptoms purple 2729, 1029 682, 272 682, 231 682, 259 682, 267 0.0286 0.0365 0.434 0.363 1.03 0.958 1.11 -0.157 0.105 0.135 0.8706 0.855 0.696 1.05 -0.047 0.103 0.646 0.1895 0.954 0.78 1.17 -0.0106 0.102 0.918 0.03732 0.989 0.81 1.21 PRS_PLINK_2.51188643150958e.06 FALSE 790.1 Elevated sedimentation rate Both 120 286 17 symptoms purple 286, 120 72, 33 71, 26 71, 27 72, 34 0.137 0.117 0.242 0.6165 1.15 0.912 1.44 -0.164 0.323 0.611 0.2137 0.849 0.45 1.6 -0.203 0.319 0.524 0.2803 0.816 0.437 1.53 0.0322 0.308 0.917 0.03773 1.03 0.565 1.89 PRS_PLINK_2.51188643150958e.06 FALSE 790.6 Other abnormal blood chemistry Both 2922 4162 17 symptoms purple 4162, 2922 1040, 732 1040, 686 1040, 741 1041, 763 0.0426 0.0246 0.0832 1.08 1.04 0.994 1.1 -0.0695 0.0699 0.32 0.4945 0.933 0.813 1.07 0.016 0.0693 0.818 0.08747 1.02 0.887 1.16 0.0643 0.069 0.351 0.4541 1.07 0.931 1.22 PRS_PLINK_2.51188643150958e.06 FALSE 790.8 Elevated C-reactive protein (CRP) Both 154 354 17 symptoms purple 354, 154 89, 52 88, 30 88, 51 89, 21 -0.0795 0.0968 0.411 0.3858 0.924 0.764 1.12 -0.484 0.292 0.0973 1.012 0.616 0.347 1.09 -0.0747 0.256 0.771 0.1132 0.928 0.562 1.53 -0.973 0.318 0.00223 2.651 0.378 0.203 0.705 PRS_PLINK_2.51188643150958e.06 FALSE 790.9 Abnormal arterial blood gases Both 63 182 17 symptoms purple 182, 63 46, 17 45, 9 45, 17 46, 20 0.114 0.171 0.507 0.295 1.12 0.801 1.57 -0.555 0.484 0.251 0.6004 0.574 0.222 1.48 -0.0753 0.415 0.856 0.06745 0.927 0.411 2.09 0.00759 0.418 0.985 0.006344 1.01 0.444 2.28 PRS_PLINK_2.51188643150958e.06 FALSE 791 Gangrene Both 107 544 17 symptoms purple 544, 107 136, 32 136, 18 136, 22 136, 35 -0.00316 0.101 0.975 0.01093 0.997 0.817 1.22 -0.512 0.317 0.107 0.9718 0.599 0.322 1.12 -0.355 0.304 0.244 0.6129 0.701 0.386 1.27 0.125 0.275 0.65 0.1871 1.13 0.66 1.94 PRS_PLINK_2.51188643150958e.06 FALSE 792 Abnormal Papanicolaou smear of cervix and cervical HPV Female 741 2174 11 genitourinary black 2174, 741 544, 178 543, 202 543, 152 544, 209 0.0773 0.0446 0.083 1.081 1.08 0.99 1.18 0.144 0.121 0.233 0.6332 1.16 0.912 1.46 -0.143 0.128 0.261 0.5832 0.866 0.675 1.11 0.155 0.121 0.2 0.6991 1.17 0.921 1.48 PRS_PLINK_2.51188643150958e.06 FALSE 792.1 Papanicolaou smear of cervix or vagina with atypical squamous cells Female 304 1357 11 genitourinary black 1357, 304 340, 72 339, 80 339, 66 339, 86 0.0891 0.0655 0.174 0.7596 1.09 0.961 1.24 0.115 0.18 0.522 0.2823 1.12 0.789 1.6 -0.0903 0.188 0.631 0.2002 0.914 0.632 1.32 0.164 0.177 0.356 0.4487 1.18 0.832 1.67 PRS_PLINK_2.51188643150958e.06 FALSE 794 Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc) Both 122 878 17 symptoms purple 878, 122 220, 35 219, 31 219, 27 220, 29 -0.0507 0.103 0.621 0.2068 0.951 0.777 1.16 -0.128 0.261 0.623 0.2052 0.88 0.527 1.47 -0.159 0.274 0.561 0.2514 0.853 0.499 1.46 -0.154 0.268 0.564 0.2486 0.857 0.507 1.45 PRS_PLINK_2.51188643150958e.06 FALSE 795 Other and nonspecific abnormal cytological, histological and immunological findings Both 552 3355 17 symptoms purple 3355, 552 839, 149 839, 130 838, 114 839, 159 0.00666 0.0468 0.887 0.05211 1.01 0.918 1.1 -0.129 0.13 0.318 0.4978 0.879 0.681 1.13 -0.286 0.134 0.0329 1.482 0.751 0.578 0.977 0.0588 0.124 0.636 0.1966 1.06 0.831 1.35 PRS_PLINK_2.51188643150958e.06 FALSE 795.8 Abnormal tumor markers Both 340 2467 17 symptoms purple 2467, 340 616, 92 617, 82 616, 76 617, 90 -0.0496 0.0567 0.382 0.4184 0.952 0.852 1.06 -0.109 0.162 0.503 0.2986 0.897 0.653 1.23 -0.203 0.165 0.22 0.6586 0.816 0.59 1.13 0.00707 0.16 0.965 0.01558 1.01 0.736 1.38 PRS_PLINK_2.51188643150958e.06 FALSE 795.81 Elevated carcinoembryonic antigen [CEA] Both 17 87 17 symptoms purple 87, 17 22, 4 22, 2 21, 1 22, 10 -0.117 0.239 0.625 0.2042 0.89 0.557 1.42 -0.139 0.911 0.879 0.05605 0.87 0.146 5.19 -2.22 1.45 0.125 0.9029 0.109 0.00641 1.85 0.797 0.735 0.278 0.5556 2.22 0.525 9.37 PRS_PLINK_2.51188643150958e.06 TRUE 795.82 Elevated cancer antigen 125 [CA 125] Both 39 351 17 symptoms purple 351, 39 88, 10 88, 6 87, 12 88, 11 0.0268 0.166 0.872 0.05957 1.03 0.742 1.42 -0.501 0.511 0.327 0.4855 0.606 0.222 1.65 0.17 0.448 0.704 0.1527 1.19 0.493 2.85 0.0309 0.453 0.946 0.02427 1.03 0.424 2.51 PRS_PLINK_2.51188643150958e.06 TRUE 796 Elevated prostate specific antigen [PSA] Male 446 1215 11 genitourinary black 1215, 446 303, 115 304, 115 303, 115 304, 101 -0.021 0.057 0.713 0.147 0.979 0.876 1.1 0.0104 0.168 0.951 0.02203 1.01 0.727 1.41 -0.0756 0.168 0.653 0.1849 0.927 0.667 1.29 -0.0507 0.172 0.768 0.1148 0.951 0.679 1.33 PRS_PLINK_2.51188643150958e.06 FALSE 797 Shock Both 243 987 17 symptoms purple 987, 243 247, 67 247, 64 246, 52 247, 60 0.0154 0.0731 0.833 0.0793 1.02 0.88 1.17 -0.0423 0.197 0.83 0.08117 0.959 0.652 1.41 -0.223 0.206 0.279 0.5539 0.8 0.534 1.2 -0.0809 0.202 0.689 0.162 0.922 0.621 1.37 PRS_PLINK_2.51188643150958e.06 FALSE 797.1 Cardiogenic shock Both 90 400 17 symptoms purple 400, 90 100, 16 100, 30 100, 18 100, 26 0.17 0.133 0.203 0.6916 1.18 0.912 1.54 0.59 0.336 0.0793 1.1 1.8 0.933 3.49 0.173 0.372 0.641 0.1929 1.19 0.574 2.46 0.463 0.351 0.187 0.7276 1.59 0.799 3.16 PRS_PLINK_2.51188643150958e.06 FALSE 798 Malaise and fatigue Both 4250 3200 17 symptoms purple 3200, 4250 800, 1069 800, 1065 800, 1069 800, 1046 0.0147 0.0237 0.536 0.2705 1.01 0.969 1.06 -0.00759 0.0673 0.91 0.04086 0.992 0.87 1.13 -0.00151 0.0673 0.982 0.007833 0.998 0.875 1.14 0.000826 0.0675 0.99 0.004261 1 0.877 1.14 PRS_PLINK_2.51188643150958e.06 FALSE 798.1 Chronic fatigue syndrome Both 841 1802 17 symptoms purple 1802, 841 451, 216 450, 196 450, 214 451, 215 -0.0316 0.0407 0.437 0.3592 0.969 0.895 1.05 -0.0756 0.12 0.53 0.2759 0.927 0.732 1.17 -0.0127 0.118 0.914 0.03888 0.987 0.784 1.24 0.0192 0.119 0.871 0.0599 1.02 0.808 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 800 Fracture of lower limb Both 664 3182 18 injuries & poisonings gray50 3182, 664 795, 184 795, 159 795, 161 796, 160 -0.00803 0.0442 0.856 0.06767 0.992 0.91 1.08 -0.156 0.121 0.198 0.7033 0.856 0.675 1.08 -0.136 0.121 0.26 0.5845 0.873 0.689 1.11 -0.113 0.121 0.35 0.4562 0.893 0.704 1.13 PRS_PLINK_2.51188643150958e.06 FALSE 800.1 Fracture of neck of femur Both 187 727 18 injuries & poisonings gray50 727, 187 182, 57 182, 32 181, 48 182, 50 0.0833 0.0896 0.352 0.4529 1.09 0.912 1.3 -0.556 0.246 0.0236 1.628 0.573 0.354 0.928 -0.161 0.225 0.475 0.323 0.852 0.548 1.32 -0.0417 0.224 0.853 0.0693 0.959 0.618 1.49 PRS_PLINK_2.51188643150958e.06 FALSE 800.2 Fracture of unspecified part of femur Both 220 897 18 injuries & poisonings gray50 897, 220 225, 66 224, 45 224, 58 224, 51 -0.0276 0.0785 0.725 0.1397 0.973 0.834 1.13 -0.39 0.219 0.0743 1.129 0.677 0.441 1.04 -0.113 0.207 0.584 0.2339 0.893 0.595 1.34 -0.16 0.214 0.453 0.3437 0.852 0.56 1.3 PRS_PLINK_2.51188643150958e.06 FALSE 800.3 Fracture of tibia and fibula Both 238 1201 18 injuries & poisonings gray50 1201, 238 301, 70 300, 64 300, 58 300, 46 -0.144 0.0683 0.0356 1.448 0.866 0.758 0.99 -0.0492 0.195 0.801 0.09663 0.952 0.65 1.39 -0.189 0.198 0.34 0.469 0.828 0.562 1.22 -0.349 0.21 0.0971 1.013 0.706 0.468 1.07 PRS_PLINK_2.51188643150958e.06 FALSE 800.4 Fracture of patella Both 98 471 18 injuries & poisonings gray50 471, 98 118, 29 118, 20 117, 23 118, 26 -0.0222 0.118 0.851 0.07015 0.978 0.776 1.23 -0.501 0.332 0.131 0.8813 0.606 0.316 1.16 -0.308 0.323 0.339 0.4693 0.735 0.39 1.38 -0.11 0.307 0.72 0.1425 0.896 0.491 1.63 PRS_PLINK_2.51188643150958e.06 FALSE 801 Fracture of ankle and foot Both 778 3230 18 injuries & poisonings gray50 3230, 778 807, 214 807, 198 807, 178 808, 188 -0.0353 0.0403 0.381 0.4188 0.965 0.892 1.04 -0.0898 0.112 0.421 0.3758 0.914 0.734 1.14 -0.195 0.115 0.089 1.051 0.822 0.657 1.03 -0.124 0.113 0.272 0.5659 0.883 0.708 1.1 PRS_PLINK_2.51188643150958e.06 FALSE 801.1 Fracture of foot Both 316 1535 18 injuries & poisonings gray50 1535, 316 383, 93 384, 71 383, 80 384, 72 -0.0316 0.062 0.61 0.2147 0.969 0.858 1.09 -0.251 0.176 0.154 0.8116 0.778 0.551 1.1 -0.189 0.172 0.273 0.5645 0.828 0.591 1.16 -0.268 0.174 0.124 0.9077 0.765 0.543 1.08 PRS_PLINK_2.51188643150958e.06 FALSE 802 Fracture of pelvis Both 121 527 18 injuries & poisonings gray50 527, 121 132, 34 132, 23 131, 34 132, 30 0.0516 0.0988 0.601 0.221 1.05 0.868 1.28 -0.417 0.309 0.177 0.7525 0.659 0.36 1.21 0.0377 0.283 0.894 0.04868 1.04 0.597 1.81 -0.128 0.285 0.654 0.1843 0.88 0.503 1.54 PRS_PLINK_2.51188643150958e.06 FALSE 803 Fracture of upper limb Both 536 2770 18 injuries & poisonings gray50 2770, 536 693, 142 692, 120 692, 133 693, 141 0.0308 0.048 0.521 0.2829 1.03 0.939 1.13 -0.219 0.136 0.108 0.9652 0.803 0.615 1.05 -0.0972 0.133 0.466 0.3315 0.907 0.699 1.18 -0.0237 0.132 0.858 0.06668 0.977 0.753 1.27 PRS_PLINK_2.51188643150958e.06 FALSE 803.1 Fracture of humerus Both 213 1002 18 injuries & poisonings gray50 1002, 213 251, 58 250, 51 250, 50 251, 54 -0.00906 0.0783 0.908 0.04198 0.991 0.85 1.16 -0.136 0.214 0.524 0.2808 0.872 0.573 1.33 -0.17 0.214 0.427 0.3698 0.844 0.555 1.28 -0.0644 0.21 0.759 0.1196 0.938 0.621 1.42 PRS_PLINK_2.51188643150958e.06 FALSE 803.2 Fracture of radius and ulna Both 299 1566 18 injuries & poisonings gray50 1566, 299 392, 78 391, 64 391, 78 392, 79 0.0322 0.0638 0.613 0.2122 1.03 0.911 1.17 -0.248 0.185 0.181 0.7417 0.78 0.543 1.12 -0.0377 0.177 0.832 0.08013 0.963 0.681 1.36 -0.0103 0.178 0.954 0.0205 0.99 0.698 1.4 PRS_PLINK_2.51188643150958e.06 FALSE 803.21 Colles' fracture Both 87 397 18 injuries & poisonings gray50 397, 87 100, 21 99, 15 99, 24 99, 27 0.0439 0.122 0.719 0.1431 1.04 0.822 1.33 -0.381 0.375 0.31 0.5083 0.683 0.328 1.43 0.105 0.335 0.753 0.1231 1.11 0.577 2.14 0.218 0.325 0.502 0.2996 1.24 0.658 2.35 PRS_PLINK_2.51188643150958e.06 FALSE 803.3 Fracture of clavicle or scapula Both 122 649 18 injuries & poisonings gray50 649, 122 163, 29 162, 27 162, 32 162, 34 0.0659 0.104 0.527 0.2784 1.07 0.871 1.31 -0.154 0.293 0.598 0.2233 0.857 0.483 1.52 0.0935 0.28 0.739 0.1315 1.1 0.634 1.9 0.195 0.28 0.486 0.3134 1.22 0.702 2.1 PRS_PLINK_2.51188643150958e.06 FALSE 804 Fracture of hand or wrist Both 445 2180 18 injuries & poisonings gray50 2180, 445 545, 123 545, 100 545, 104 545, 118 -0.0287 0.0493 0.56 0.2518 0.972 0.882 1.07 -0.222 0.149 0.136 0.8672 0.801 0.598 1.07 -0.179 0.148 0.228 0.6422 0.836 0.626 1.12 -0.03 0.144 0.835 0.07819 0.97 0.731 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 805 Fracture of vertebral column without mention of spinal cord injury Both 470 1894 18 injuries & poisonings gray50 1894, 470 474, 138 473, 109 473, 104 474, 119 -0.0711 0.0511 0.164 0.7844 0.931 0.843 1.03 -0.232 0.144 0.108 0.9676 0.793 0.597 1.05 -0.245 0.146 0.0943 1.026 0.783 0.587 1.04 -0.138 0.142 0.332 0.4795 0.871 0.66 1.15 PRS_PLINK_2.51188643150958e.06 FALSE 807 Fracture of ribs Both 263 967 18 injuries & poisonings gray50 967, 263 242, 68 242, 62 241, 58 242, 75 0.0172 0.0757 0.82 0.08629 1.02 0.877 1.18 -0.059 0.199 0.767 0.1152 0.943 0.638 1.39 -0.127 0.205 0.534 0.2722 0.881 0.59 1.31 0.0985 0.193 0.61 0.2147 1.1 0.756 1.61 PRS_PLINK_2.51188643150958e.06 FALSE 809 Fracture of unspecified bones Both 795 3932 18 injuries & poisonings gray50 3932, 795 983, 210 983, 181 983, 184 983, 220 0.0141 0.0398 0.723 0.1409 1.01 0.938 1.1 -0.188 0.113 0.0971 1.013 0.829 0.664 1.03 -0.148 0.113 0.189 0.7226 0.863 0.692 1.08 0.0483 0.109 0.657 0.1822 1.05 0.848 1.3 PRS_PLINK_2.51188643150958e.06 FALSE 816 Cerebral laceration and contusion Both 21 74 18 injuries & poisonings gray50 74, 21 19, 2 18, 5 18, 6 19, 8 0.315 0.317 0.32 0.4954 1.37 0.737 2.55 -0.051 0.895 0.955 0.02019 0.95 0.164 5.49 1.25 0.856 0.145 0.84 3.49 0.651 18.7 1.06 0.905 0.243 0.6142 2.88 0.488 17 PRS_PLINK_2.51188643150958e.06 TRUE 817 Concussion Both 317 1489 18 injuries & poisonings gray50 1489, 317 373, 90 372, 85 372, 74 372, 68 -0.0822 0.0579 0.156 0.8063 0.921 0.822 1.03 -0.0633 0.169 0.708 0.1497 0.939 0.674 1.31 -0.18 0.175 0.303 0.5186 0.835 0.593 1.18 -0.26 0.178 0.143 0.8434 0.771 0.544 1.09 PRS_PLINK_2.51188643150958e.06 FALSE 818 Intracranial hemorrhage (injury) Both 116 560 18 injuries & poisonings gray50 560, 116 140, 27 140, 13 140, 46 140, 30 -0.0162 0.0995 0.871 0.05998 0.984 0.81 1.2 -0.632 0.348 0.0699 1.156 0.532 0.269 1.05 0.666 0.281 0.0177 1.752 1.95 1.12 3.37 0.157 0.295 0.594 0.226 1.17 0.656 2.09 PRS_PLINK_2.51188643150958e.06 FALSE 818.1 Subdural hemorrhage (injury) Both 37 159 18 injuries & poisonings gray50 159, 37 40, 11 40, 3 39, 14 40, 9 -0.141 0.191 0.459 0.3378 0.868 0.598 1.26 -0.845 0.654 0.196 0.7072 0.429 0.119 1.55 0.337 0.484 0.486 0.3132 1.4 0.542 3.62 -0.228 0.523 0.663 0.1784 0.796 0.286 2.22 PRS_PLINK_2.51188643150958e.06 TRUE 818.2 Subarachnoid hemorrhage (injury) Both 31 178 18 injuries & poisonings gray50 178, 31 45, 4 44, 5 44, 14 45, 8 0.0693 0.213 0.745 0.1278 1.07 0.706 1.63 0.166 0.63 0.792 0.1012 1.18 0.343 4.06 1.14 0.577 0.0483 1.316 3.12 1.01 9.68 0.861 0.64 0.179 0.7482 2.37 0.675 8.3 PRS_PLINK_2.51188643150958e.06 TRUE 819 Skull and face fracture and other intercranial injury Both 660 3298 18 injuries & poisonings gray50 3298, 660 825, 158 824, 164 824, 181 825, 157 -0.00959 0.043 0.823 0.0844 0.99 0.91 1.08 0.0252 0.122 0.837 0.07743 1.03 0.807 1.3 0.144 0.12 0.231 0.636 1.15 0.912 1.46 -6.37e-05 0.124 1 0.0001788 1 0.785 1.27 PRS_PLINK_2.51188643150958e.06 FALSE 830 Dislocation Both 967 5142 18 injuries & poisonings gray50 5142, 967 1286, 250 1285, 265 1285, 221 1286, 231 -0.0283 0.0353 0.423 0.3738 0.972 0.907 1.04 0.0542 0.0974 0.577 0.2385 1.06 0.872 1.28 -0.124 0.101 0.222 0.6528 0.884 0.724 1.08 -0.0683 0.101 0.498 0.3027 0.934 0.767 1.14 PRS_PLINK_2.51188643150958e.06 FALSE 835 Internal derangement of knee Both 560 3172 18 injuries & poisonings gray50 3172, 560 793, 139 793, 152 793, 130 793, 139 -0.00838 0.0462 0.856 0.06759 0.992 0.906 1.09 0.0732 0.129 0.571 0.2434 1.08 0.835 1.39 -0.0804 0.134 0.547 0.2617 0.923 0.71 1.2 0.00946 0.133 0.943 0.02543 1.01 0.778 1.31 PRS_PLINK_2.51188643150958e.06 FALSE 836 Traumatic arthropathy Both 128 779 18 injuries & poisonings gray50 779, 128 195, 35 195, 33 194, 27 195, 33 -0.078 0.0902 0.387 0.4124 0.925 0.775 1.1 -0.0883 0.264 0.738 0.1322 0.915 0.546 1.53 -0.184 0.274 0.501 0.3002 0.832 0.486 1.42 -0.00498 0.267 0.985 0.006511 0.995 0.59 1.68 PRS_PLINK_2.51188643150958e.06 FALSE 840 Sprains and strains Both 2143 5037 18 injuries & poisonings gray50 5037, 2143 1259, 527 1259, 547 1259, 531 1259, 538 0.0215 0.0263 0.412 0.3849 1.02 0.971 1.08 0.029 0.0736 0.694 0.1587 1.03 0.891 1.19 0.0147 0.0739 0.842 0.07469 1.01 0.878 1.17 0.0442 0.0741 0.551 0.2588 1.05 0.904 1.21 PRS_PLINK_2.51188643150958e.06 FALSE 840.1 Muscle/tendon sprain Both 194 755 18 injuries & poisonings gray50 755, 194 189, 49 189, 49 188, 47 189, 49 0.0242 0.0788 0.758 0.1201 1.02 0.878 1.2 0.0192 0.229 0.933 0.03006 1.02 0.651 1.6 -0.067 0.23 0.771 0.1131 0.935 0.596 1.47 0.0237 0.227 0.917 0.03767 1.02 0.656 1.6 PRS_PLINK_2.51188643150958e.06 FALSE 840.2 Rotator cuff (capsule) sprain Both 542 2349 18 injuries & poisonings gray50 2349, 542 588, 157 587, 140 587, 115 587, 130 -0.0585 0.0459 0.202 0.6938 0.943 0.862 1.03 -0.115 0.131 0.383 0.4169 0.892 0.689 1.15 -0.3 0.136 0.0278 1.556 0.741 0.567 0.968 -0.167 0.133 0.21 0.6779 0.846 0.652 1.1 PRS_PLINK_2.51188643150958e.06 FALSE 840.3 Joint/ligament sprain Both 670 3222 18 injuries & poisonings gray50 3222, 670 806, 168 805, 180 805, 149 806, 173 0.0148 0.0428 0.73 0.1367 1.01 0.933 1.1 0.064 0.12 0.593 0.2272 1.07 0.843 1.35 -0.15 0.124 0.228 0.642 0.861 0.675 1.1 0.0438 0.121 0.718 0.144 1.04 0.824 1.32 PRS_PLINK_2.51188643150958e.06 FALSE 841 Sprains and strains of back and neck Both 570 2159 18 injuries & poisonings gray50 2159, 570 540, 139 540, 142 539, 146 540, 143 0.0139 0.0479 0.771 0.1129 1.01 0.923 1.11 0.0131 0.135 0.923 0.03493 1.01 0.777 1.32 0.0369 0.135 0.785 0.1053 1.04 0.796 1.35 0.0713 0.135 0.599 0.2228 1.07 0.823 1.4 PRS_PLINK_2.51188643150958e.06 FALSE 842 Other sprains and strains Both 428 1871 18 injuries & poisonings gray50 1871, 428 468, 106 468, 116 467, 104 468, 102 -0.0039 0.0547 0.943 0.02544 0.996 0.895 1.11 0.0705 0.151 0.641 0.1931 1.07 0.798 1.44 -0.0435 0.155 0.778 0.1089 0.957 0.707 1.3 -0.01 0.156 0.949 0.02285 0.99 0.729 1.34 PRS_PLINK_2.51188643150958e.06 FALSE 850 Hemorrhage or hematoma complicating a procedure Both 571 2961 18 injuries & poisonings gray50 2961, 571 740, 136 740, 125 740, 163 740, 147 0.0401 0.0458 0.381 0.4192 1.04 0.952 1.14 -0.0744 0.134 0.58 0.2366 0.928 0.713 1.21 0.184 0.127 0.148 0.8298 1.2 0.937 1.54 0.0855 0.13 0.51 0.2923 1.09 0.845 1.4 PRS_PLINK_2.51188643150958e.06 FALSE 851 Complications of transplants and reattached limbs Both 860 3711 18 injuries & poisonings gray50 3711, 860 927, 234 928, 187 927, 233 928, 206 0.0193 0.0382 0.614 0.2117 1.02 0.946 1.1 -0.204 0.109 0.0609 1.216 0.815 0.658 1.01 0.0108 0.104 0.917 0.03759 1.01 0.824 1.24 -0.116 0.107 0.277 0.5577 0.89 0.722 1.1 PRS_PLINK_2.51188643150958e.06 FALSE 853 Complication of colostomy or enterostomy Both 198 608 18 injuries & poisonings gray50 608, 198 152, 52 152, 36 152, 50 152, 60 0.152 0.0897 0.0907 1.042 1.16 0.976 1.39 -0.32 0.247 0.196 0.708 0.726 0.447 1.18 0.0175 0.233 0.94 0.02672 1.02 0.644 1.61 0.151 0.225 0.5 0.3007 1.16 0.749 1.81 PRS_PLINK_2.51188643150958e.06 FALSE 854 Complications of cardiac/vascular device, implant, and graft Both 716 2763 18 injuries & poisonings gray50 2763, 716 690, 191 691, 147 690, 190 691, 188 0.0536 0.042 0.202 0.6942 1.06 0.972 1.15 -0.242 0.123 0.0482 1.317 0.785 0.617 0.998 0.0206 0.116 0.86 0.06575 1.02 0.813 1.28 0.00349 0.117 0.976 0.01046 1 0.798 1.26 PRS_PLINK_2.51188643150958e.06 FALSE 855 Complication of nervous system device, implant, and graft Both 68 383 18 injuries & poisonings gray50 383, 68 96, 17 96, 19 95, 16 96, 16 -0.0202 0.124 0.871 0.06013 0.98 0.769 1.25 0.133 0.373 0.722 0.1415 1.14 0.55 2.37 0.0761 0.382 0.842 0.07463 1.08 0.51 2.28 0.161 0.384 0.675 0.1705 1.17 0.554 2.49 PRS_PLINK_2.51188643150958e.06 FALSE 856 Vascular complications of surgery and medical procedures Both 85 443 18 injuries & poisonings gray50 443, 85 111, 15 111, 21 110, 31 111, 18 0.117 0.125 0.346 0.4609 1.12 0.881 1.44 0.367 0.371 0.323 0.4914 1.44 0.697 2.99 0.69 0.349 0.0481 1.318 1.99 1.01 3.95 0.174 0.365 0.633 0.1985 1.19 0.582 2.44 PRS_PLINK_2.51188643150958e.06 FALSE 857 Mechanical complication of unspecified genitourinary device, implant, and graft Both 342 1807 18 injuries & poisonings gray50 1807, 342 451, 89 452, 85 451, 73 452, 95 0.0659 0.0592 0.265 0.5761 1.07 0.951 1.2 -0.0618 0.167 0.711 0.1483 0.94 0.678 1.3 -0.197 0.172 0.25 0.6016 0.821 0.586 1.15 0.0656 0.164 0.689 0.162 1.07 0.775 1.47 PRS_PLINK_2.51188643150958e.06 FALSE 858 Complication of internal orthopedic device Both 441 2856 18 injuries & poisonings gray50 2856, 441 714, 118 714, 112 714, 110 714, 101 -0.0179 0.05 0.721 0.1422 0.982 0.891 1.08 -0.0536 0.143 0.708 0.15 0.948 0.716 1.25 -0.0706 0.143 0.621 0.207 0.932 0.704 1.23 -0.124 0.147 0.399 0.3989 0.884 0.663 1.18 PRS_PLINK_2.51188643150958e.06 FALSE 859 Complication due to other implant and internal device Both 573 2914 18 injuries & poisonings gray50 2914, 573 728, 145 728, 133 728, 138 729, 157 0.0257 0.0456 0.573 0.2419 1.03 0.938 1.12 -0.0666 0.131 0.612 0.2134 0.936 0.723 1.21 -0.0473 0.13 0.716 0.1449 0.954 0.739 1.23 0.108 0.127 0.395 0.4033 1.11 0.868 1.43 PRS_PLINK_2.51188643150958e.06 FALSE 860 Bone marrow or stem cell transplant Both 79 281 2 neoplasms darkcyan 281, 79 71, 15 70, 19 70, 21 70, 24 0.162 0.145 0.266 0.5744 1.18 0.884 1.56 0.162 0.384 0.674 0.1714 1.18 0.554 2.5 0.276 0.386 0.475 0.3233 1.32 0.618 2.81 0.467 0.368 0.205 0.6875 1.59 0.775 3.28 PRS_PLINK_2.51188643150958e.06 FALSE 870 Open wounds of head; neck; and trunk Both 1175 5026 18 injuries & poisonings gray50 5026, 1175 1256, 282 1256, 289 1256, 295 1257, 309 0.0255 0.0329 0.438 0.3589 1.03 0.962 1.09 0.0148 0.0933 0.874 0.05867 1.01 0.845 1.22 0.0471 0.0929 0.612 0.2131 1.05 0.874 1.26 0.0907 0.0925 0.327 0.4857 1.09 0.913 1.31 PRS_PLINK_2.51188643150958e.06 FALSE 870.1 Open wound or laceration of eye or eyelid Both 48 278 18 injuries & poisonings gray50 278, 48 70, 12 69, 12 69, 12 70, 12 0.163 0.172 0.343 0.4645 1.18 0.84 1.65 -0.25 0.452 0.579 0.237 0.778 0.321 1.89 -0.219 0.446 0.623 0.2055 0.803 0.335 1.93 0.0393 0.44 0.929 0.03209 1.04 0.439 2.46 PRS_PLINK_2.51188643150958e.06 TRUE 870.2 Open wound of ear Both 43 192 18 injuries & poisonings gray50 192, 43 48, 10 48, 9 48, 13 48, 11 0.021 0.166 0.899 0.04619 1.02 0.738 1.41 0.00906 0.52 0.986 0.006079 1.01 0.364 2.8 0.33 0.47 0.482 0.3171 1.39 0.554 3.49 0.416 0.543 0.443 0.3533 1.52 0.523 4.4 PRS_PLINK_2.51188643150958e.06 TRUE 870.3 Other open wound of head and face Both 373 1852 18 injuries & poisonings gray50 1852, 373 463, 91 463, 94 463, 90 463, 98 0.00808 0.0572 0.888 0.0517 1.01 0.901 1.13 0.0313 0.161 0.846 0.0725 1.03 0.752 1.42 -0.00844 0.163 0.959 0.01825 0.992 0.72 1.37 0.0961 0.161 0.551 0.2592 1.1 0.803 1.51 PRS_PLINK_2.51188643150958e.06 FALSE 870.4 Open wound of nose and sinus Both 39 315 18 injuries & poisonings gray50 315, 39 79, 9 79, 14 78, 9 79, 7 -0.255 0.15 0.0905 1.043 0.775 0.577 1.04 0.508 0.449 0.258 0.5879 1.66 0.689 4.01 -0.0451 0.476 0.925 0.03408 0.956 0.376 2.43 -0.359 0.509 0.48 0.3189 0.698 0.258 1.89 PRS_PLINK_2.51188643150958e.06 TRUE 870.5 Open wound of lip and mouth Both 62 376 18 injuries & poisonings gray50 376, 62 94, 19 94, 14 94, 15 94, 14 -0.0952 0.146 0.514 0.2889 0.909 0.683 1.21 -0.371 0.387 0.338 0.4706 0.69 0.323 1.47 -0.175 0.379 0.645 0.1906 0.84 0.4 1.76 -0.256 0.383 0.504 0.2978 0.774 0.366 1.64 PRS_PLINK_2.51188643150958e.06 FALSE 870.6 Open wound of neck Both 30 278 18 injuries & poisonings gray50 278, 30 70, 8 69, 9 69, 10 70, 3 -0.215 0.176 0.224 0.6503 0.807 0.571 1.14 0.154 0.529 0.772 0.1125 1.17 0.413 3.29 0.18 0.48 0.708 0.1498 1.2 0.467 3.07 -0.95 0.632 0.133 0.8767 0.387 0.112 1.33 PRS_PLINK_2.51188643150958e.06 TRUE 870.8 Open wound of genital organs Both 32 193 18 injuries & poisonings gray50 193, 32 49, 5 48, 6 48, 4 48, 17 0.629 0.228 0.00567 2.246 1.88 1.2 2.93 0.126 0.619 0.838 0.07673 1.13 0.338 3.81 -0.297 0.666 0.656 0.1833 0.743 0.202 2.74 0.96 0.526 0.0678 1.169 2.61 0.932 7.31 PRS_PLINK_2.51188643150958e.06 TRUE 871 Open wounds of extremities Both 1135 4530 18 injuries & poisonings gray50 4530, 1135 1132, 275 1132, 272 1132, 264 1133, 324 0.0664 0.0348 0.0564 1.249 1.07 0.998 1.14 -0.000704 0.0959 0.994 0.002553 0.999 0.828 1.21 -0.015 0.0969 0.877 0.05698 0.985 0.815 1.19 0.183 0.0931 0.049 1.309 1.2 1 1.44 PRS_PLINK_2.51188643150958e.06 FALSE 871.1 Open wound of hand except finger(s) Both 175 790 18 injuries & poisonings gray50 790, 175 198, 41 197, 38 197, 43 198, 53 0.061 0.0879 0.488 0.3114 1.06 0.895 1.26 0.069 0.254 0.785 0.1049 1.07 0.652 1.76 0.0198 0.246 0.936 0.02884 1.02 0.63 1.65 0.285 0.235 0.224 0.649 1.33 0.84 2.11 PRS_PLINK_2.51188643150958e.06 FALSE 871.2 Open wound of finger(s) Both 330 1396 18 injuries & poisonings gray50 1396, 330 349, 77 349, 77 349, 75 349, 101 0.0488 0.0631 0.439 0.3574 1.05 0.928 1.19 0.0184 0.179 0.918 0.03722 1.02 0.718 1.45 0.0199 0.181 0.913 0.03973 1.02 0.716 1.45 0.251 0.173 0.146 0.8364 1.29 0.917 1.8 PRS_PLINK_2.51188643150958e.06 FALSE 871.3 Open wound of foot except toe(s) alone Both 199 793 18 injuries & poisonings gray50 793, 199 199, 48 198, 40 198, 49 198, 62 0.116 0.0828 0.16 0.7959 1.12 0.955 1.32 -0.12 0.244 0.624 0.2047 0.887 0.55 1.43 0.0349 0.23 0.88 0.05568 1.04 0.659 1.63 0.261 0.221 0.239 0.622 1.3 0.841 2 PRS_PLINK_2.51188643150958e.06 FALSE 871.4 Open wound of toe(s) Both 128 513 18 injuries & poisonings gray50 513, 128 129, 29 128, 35 128, 34 128, 30 0.0555 0.104 0.593 0.2271 1.06 0.863 1.3 0.32 0.286 0.263 0.5801 1.38 0.786 2.41 0.282 0.288 0.327 0.4853 1.33 0.754 2.33 0.229 0.301 0.445 0.3512 1.26 0.698 2.27 PRS_PLINK_2.51188643150958e.06 FALSE 872 Traumatic amputation Both 158 761 18 injuries & poisonings gray50 761, 158 191, 37 190, 39 190, 31 190, 51 0.101 0.0906 0.265 0.5775 1.11 0.926 1.32 0.087 0.253 0.731 0.136 1.09 0.664 1.79 -0.071 0.269 0.792 0.1012 0.931 0.549 1.58 0.395 0.248 0.111 0.9553 1.48 0.913 2.41 PRS_PLINK_2.51188643150958e.06 FALSE 874 Complication of amputation stump Both 52 226 18 injuries & poisonings gray50 226, 52 57, 16 56, 12 56, 9 57, 15 0.0214 0.147 0.884 0.05344 1.02 0.766 1.36 -0.284 0.449 0.526 0.2789 0.752 0.312 1.81 -0.323 0.467 0.489 0.3106 0.724 0.29 1.81 -0.0381 0.414 0.927 0.03312 0.963 0.428 2.17 PRS_PLINK_2.51188643150958e.06 FALSE 875 Non-healing surgical wound Both 150 796 18 injuries & poisonings gray50 796, 150 199, 42 199, 28 199, 37 199, 43 0.109 0.0974 0.264 0.578 1.11 0.921 1.35 -0.315 0.265 0.235 0.6292 0.73 0.434 1.23 -0.113 0.249 0.65 0.1872 0.893 0.548 1.46 0.0703 0.243 0.773 0.1121 1.07 0.666 1.73 PRS_PLINK_2.51188643150958e.06 FALSE 876 Posttraumatic wound infection not elsewhere classified Both 272 1170 18 injuries & poisonings gray50 1170, 272 293, 66 292, 61 292, 76 293, 69 0.0356 0.0735 0.628 0.2022 1.04 0.897 1.2 -0.051 0.198 0.796 0.09886 0.95 0.645 1.4 0.146 0.188 0.438 0.3589 1.16 0.8 1.67 0.0221 0.193 0.909 0.04148 1.02 0.7 1.49 PRS_PLINK_2.51188643150958e.06 FALSE 907 Injuries to the nervous system Both 234 1506 18 injuries & poisonings gray50 1506, 234 377, 58 376, 59 376, 51 377, 66 0.0521 0.0714 0.466 0.3318 1.05 0.916 1.21 0.000131 0.198 0.999 0.0002296 1 0.679 1.47 -0.0971 0.205 0.636 0.1965 0.907 0.607 1.36 0.132 0.194 0.495 0.3057 1.14 0.781 1.67 PRS_PLINK_2.51188643150958e.06 FALSE 910 Superficial injury, infected Both 46 192 18 injuries & poisonings gray50 192, 46 48, 12 48, 11 48, 11 48, 12 0.00619 0.181 0.973 0.01198 1.01 0.705 1.44 0.0411 0.502 0.935 0.02925 1.04 0.389 2.79 -0.013 0.518 0.98 0.008783 0.987 0.358 2.72 -0.105 0.519 0.839 0.07604 0.9 0.326 2.49 PRS_PLINK_2.51188643150958e.06 TRUE 911 Blister Both 136 623 18 injuries & poisonings gray50 623, 136 156, 26 156, 34 155, 33 156, 43 0.172 0.103 0.0941 1.026 1.19 0.971 1.45 0.329 0.289 0.255 0.594 1.39 0.789 2.45 0.259 0.292 0.375 0.4261 1.3 0.731 2.3 0.47 0.274 0.0864 1.064 1.6 0.935 2.74 PRS_PLINK_2.51188643150958e.06 FALSE 912 Insect bite Both 172 828 18 injuries & poisonings gray50 828, 172 207, 45 207, 58 207, 36 207, 33 -0.119 0.0839 0.156 0.806 0.888 0.753 1.05 0.224 0.224 0.317 0.499 1.25 0.806 1.94 -0.232 0.243 0.339 0.4692 0.793 0.492 1.28 -0.344 0.249 0.167 0.7772 0.709 0.435 1.15 PRS_PLINK_2.51188643150958e.06 FALSE 913 Toxic effect of venom Both 117 564 18 injuries & poisonings gray50 564, 117 141, 27 141, 34 141, 26 141, 30 0.062 0.11 0.573 0.242 1.06 0.858 1.32 0.149 0.285 0.6 0.2217 1.16 0.664 2.03 0.085 0.308 0.782 0.1067 1.09 0.596 1.99 0.0725 0.296 0.807 0.09338 1.08 0.602 1.92 PRS_PLINK_2.51188643150958e.06 FALSE 916 Contusion Both 1563 5396 18 injuries & poisonings gray50 5396, 1563 1348, 416 1349, 363 1349, 398 1349, 386 -0.00311 0.0288 0.914 0.03905 0.997 0.942 1.05 -0.143 0.0822 0.0831 1.08 0.867 0.738 1.02 -0.0322 0.0809 0.691 0.1607 0.968 0.826 1.13 -0.0591 0.0813 0.467 0.3307 0.943 0.804 1.11 PRS_PLINK_2.51188643150958e.06 FALSE 930 Allergic reaction to food Both 267 801 18 injuries & poisonings gray50 801, 267 201, 64 200, 73 200, 80 200, 50 0.0147 0.0709 0.835 0.07816 1.01 0.883 1.17 0.118 0.2 0.556 0.2551 1.12 0.761 1.66 0.208 0.199 0.296 0.5294 1.23 0.834 1.82 -0.256 0.219 0.242 0.6168 0.774 0.504 1.19 PRS_PLINK_2.51188643150958e.06 FALSE 931 Contact dermatitis and other eczema due to plants [except food] Both 207 783 13 dermatologic firebrick 783, 207 196, 62 196, 52 195, 51 196, 42 -0.0343 0.077 0.656 0.1829 0.966 0.831 1.12 -0.155 0.216 0.474 0.3242 0.857 0.561 1.31 -0.106 0.218 0.628 0.2018 0.9 0.587 1.38 -0.338 0.229 0.14 0.8532 0.713 0.455 1.12 PRS_PLINK_2.51188643150958e.06 FALSE 938 Dermatitis due to solar radiation Both 1842 3018 13 dermatologic firebrick 3018, 1842 754, 437 754, 461 754, 460 755, 484 0.0565 0.0302 0.0612 1.214 1.06 0.997 1.12 0.0507 0.0878 0.563 0.2492 1.05 0.886 1.25 0.0607 0.0875 0.488 0.3115 1.06 0.895 1.26 0.119 0.0869 0.17 0.7684 1.13 0.95 1.34 PRS_PLINK_2.51188643150958e.06 FALSE 938.1 Acute dermatitis due to solar radiation Both 84 245 13 dermatologic firebrick 245, 84 62, 15 61, 22 61, 25 61, 22 0.176 0.136 0.196 0.7088 1.19 0.913 1.56 0.353 0.393 0.369 0.4331 1.42 0.659 3.08 0.593 0.389 0.128 0.8938 1.81 0.844 3.88 0.408 0.381 0.284 0.5466 1.5 0.713 3.18 PRS_PLINK_2.51188643150958e.06 FALSE 938.2 Chronic dermatitis due to solar radiation Both 1776 2978 13 dermatologic firebrick 2978, 1776 744, 417 744, 445 744, 446 745, 468 0.0574 0.0307 0.0609 1.215 1.06 0.997 1.12 0.0539 0.0893 0.546 0.2631 1.06 0.886 1.26 0.0683 0.0888 0.441 0.3551 1.07 0.9 1.27 0.126 0.0883 0.153 0.8153 1.13 0.954 1.35 PRS_PLINK_2.51188643150958e.06 FALSE 939 Atopic/contact dermatitis due to other or unspecified Both 2309 3184 13 dermatologic firebrick 3184, 2309 795, 531 796, 582 796, 631 796, 565 0.0602 0.028 0.0316 1.5 1.06 1.01 1.12 0.0777 0.0803 0.333 0.4774 1.08 0.923 1.26 0.168 0.0794 0.034 1.468 1.18 1.01 1.38 0.0869 0.0804 0.28 0.553 1.09 0.932 1.28 PRS_PLINK_2.51188643150958e.06 FALSE 939.1 Contact and allergic dermatitis of eyelid Both 31 105 13 dermatologic firebrick 105, 31 27, 8 26, 8 26, 7 26, 8 0.0391 0.187 0.834 0.07879 1.04 0.721 1.5 -0.0528 0.585 0.928 0.03242 0.949 0.302 2.98 -0.0446 0.634 0.944 0.0251 0.956 0.276 3.31 -0.263 0.615 0.669 0.1745 0.769 0.23 2.57 PRS_PLINK_2.51188643150958e.06 TRUE 941 Adverse reaction to serum or vaccine Both 88 215 18 injuries & poisonings gray50 215, 88 54, 29 54, 16 53, 26 54, 17 -0.0945 0.112 0.4 0.3979 0.91 0.73 1.13 -0.681 0.373 0.0678 1.169 0.506 0.244 1.05 -0.0945 0.342 0.782 0.1067 0.91 0.465 1.78 -0.508 0.372 0.172 0.7647 0.602 0.29 1.25 PRS_PLINK_2.51188643150958e.06 FALSE 942 Infusion and transfusion reaction Both 118 296 18 injuries & poisonings gray50 296, 118 74, 30 74, 24 74, 35 74, 29 -0.0553 0.102 0.588 0.2303 0.946 0.774 1.16 -0.116 0.331 0.726 0.1388 0.891 0.466 1.7 0.142 0.307 0.643 0.1915 1.15 0.632 2.1 -0.0417 0.312 0.894 0.04879 0.959 0.52 1.77 PRS_PLINK_2.51188643150958e.06 FALSE 946 Anaphylactic shock NOS Both 199 520 18 injuries & poisonings gray50 520, 199 130, 54 130, 47 130, 49 130, 49 -0.0014 0.0824 0.986 0.005933 0.999 0.85 1.17 -0.159 0.236 0.501 0.3005 0.853 0.537 1.36 -0.0937 0.235 0.69 0.1611 0.911 0.574 1.44 -0.0408 0.239 0.864 0.06331 0.96 0.601 1.53 PRS_PLINK_2.51188643150958e.06 FALSE 947 Urticaria Both 434 1198 13 dermatologic firebrick 1198, 434 300, 105 299, 121 299, 111 300, 97 0.0246 0.0554 0.657 0.1824 1.02 0.92 1.14 0.127 0.158 0.423 0.3735 1.14 0.832 1.55 0.0412 0.161 0.798 0.0978 1.04 0.76 1.43 -0.0688 0.164 0.675 0.1709 0.934 0.677 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 949 Allergies, other Both 2264 3179 18 injuries & poisonings gray50 3179, 2264 794, 524 795, 598 794, 582 795, 560 0.0575 0.028 0.0404 1.394 1.06 1 1.12 0.111 0.0803 0.167 0.7768 1.12 0.955 1.31 0.128 0.0804 0.112 0.9524 1.14 0.971 1.33 0.0825 0.0812 0.309 0.5094 1.09 0.926 1.27 PRS_PLINK_2.51188643150958e.06 FALSE 952 Spinal cord injury without evidence of spinal bone injury Both 137 732 18 injuries & poisonings gray50 732, 137 183, 31 183, 25 183, 35 183, 46 0.0813 0.103 0.431 0.3659 1.08 0.886 1.33 -0.22 0.291 0.45 0.3469 0.803 0.454 1.42 0.12 0.272 0.66 0.1808 1.13 0.662 1.92 0.411 0.259 0.113 0.9488 1.51 0.908 2.51 PRS_PLINK_2.51188643150958e.06 FALSE 957 Injury to other and unspecified nerves Both 26 171 18 injuries & poisonings gray50 171, 26 43, 7 43, 7 42, 2 43, 10 0.202 0.232 0.385 0.4145 1.22 0.776 1.93 -0.216 0.575 0.708 0.1502 0.806 0.261 2.49 -0.892 0.718 0.214 0.6688 0.41 0.1 1.68 0.324 0.537 0.546 0.2626 1.38 0.483 3.96 PRS_PLINK_2.51188643150958e.06 TRUE 958 Certain early complications of trauma or procedure Both 370 1891 18 injuries & poisonings gray50 1891, 370 473, 89 473, 98 472, 90 473, 93 0.0533 0.0589 0.366 0.4371 1.05 0.94 1.18 0.127 0.161 0.43 0.3663 1.14 0.828 1.56 0.0295 0.164 0.857 0.0669 1.03 0.747 1.42 0.0535 0.164 0.744 0.1284 1.05 0.765 1.45 PRS_PLINK_2.51188643150958e.06 FALSE 958.1 Postoperative shock Both 50 281 18 injuries & poisonings gray50 281, 50 71, 15 70, 10 70, 8 70, 17 0.152 0.17 0.372 0.4296 1.16 0.834 1.62 -0.484 0.444 0.276 0.5597 0.616 0.258 1.47 -0.667 0.47 0.155 0.8083 0.513 0.204 1.29 0.214 0.404 0.596 0.2248 1.24 0.561 2.73 PRS_PLINK_2.51188643150958e.06 TRUE 958.2 Traumatic and surgical subcutaneous emphysema Both 31 154 18 injuries & poisonings gray50 154, 31 39, 7 38, 10 38, 8 39, 6 0.00615 0.225 0.978 0.009588 1.01 0.648 1.56 0.52 0.547 0.342 0.4663 1.68 0.576 4.92 0.304 0.564 0.59 0.2289 1.35 0.449 4.09 -0.394 0.63 0.531 0.2746 0.674 0.196 2.32 PRS_PLINK_2.51188643150958e.06 TRUE 960 Poisoning by antibiotics Both 811 2814 18 injuries & poisonings gray50 2814, 811 704, 193 703, 190 703, 223 704, 205 0.0517 0.041 0.207 0.6836 1.05 0.972 1.14 -0.0151 0.116 0.896 0.04754 0.985 0.785 1.24 0.15 0.112 0.182 0.7401 1.16 0.932 1.45 0.0655 0.115 0.568 0.2454 1.07 0.852 1.34 PRS_PLINK_2.51188643150958e.06 FALSE 960.1 Adverse effects of antibacterials (not penicillins) Both 137 447 18 injuries & poisonings gray50 447, 137 112, 32 112, 34 111, 34 112, 37 0.0118 0.105 0.91 0.04108 1.01 0.824 1.24 0.0653 0.289 0.821 0.0856 1.07 0.606 1.88 0.0827 0.284 0.771 0.1131 1.09 0.623 1.89 0.188 0.281 0.503 0.2989 1.21 0.696 2.09 PRS_PLINK_2.51188643150958e.06 FALSE 960.2 Allergy/adverse effect of penicillin Both 509 2056 18 injuries & poisonings gray50 2056, 509 514, 128 514, 113 514, 138 514, 130 0.0389 0.0501 0.438 0.3589 1.04 0.942 1.15 -0.0951 0.145 0.511 0.2912 0.909 0.685 1.21 0.119 0.139 0.394 0.4041 1.13 0.857 1.48 0.0319 0.141 0.821 0.08579 1.03 0.783 1.36 PRS_PLINK_2.51188643150958e.06 FALSE 961 Poisoning by other anti-infectives Both 237 745 18 injuries & poisonings gray50 745, 237 187, 61 186, 51 186, 75 186, 50 0.0145 0.0678 0.831 0.0805 1.01 0.888 1.16 -0.166 0.218 0.448 0.3489 0.847 0.552 1.3 0.215 0.204 0.29 0.537 1.24 0.832 1.85 -0.18 0.221 0.417 0.3802 0.835 0.541 1.29 PRS_PLINK_2.51188643150958e.06 FALSE 961.1 Poisoning/allergy of sulfonamides Both 341 1463 18 injuries & poisonings gray50 1463, 341 366, 84 366, 74 365, 112 366, 71 -0.00935 0.0589 0.874 0.05853 0.991 0.883 1.11 -0.193 0.178 0.278 0.5565 0.825 0.582 1.17 0.269 0.163 0.0981 1.008 1.31 0.951 1.8 -0.17 0.178 0.339 0.4692 0.843 0.594 1.2 PRS_PLINK_2.51188643150958e.06 FALSE 962 Poisoning by hormones and synthetic substitutes Both 370 1077 18 injuries & poisonings gray50 1077, 370 270, 109 269, 79 269, 96 269, 86 -0.0457 0.0625 0.465 0.3329 0.955 0.845 1.08 -0.325 0.174 0.0619 1.208 0.723 0.514 1.02 -0.0995 0.168 0.554 0.2566 0.905 0.651 1.26 -0.242 0.173 0.16 0.7951 0.785 0.559 1.1 PRS_PLINK_2.51188643150958e.06 FALSE 962.1 Adrenal cortical steroids causing adverse effects in therapeutic use Both 188 501 18 injuries & poisonings gray50 501, 188 126, 50 125, 38 125, 57 125, 43 -0.00792 0.0946 0.933 0.03001 0.992 0.824 1.19 -0.328 0.256 0.2 0.6982 0.72 0.436 1.19 0.138 0.235 0.559 0.2525 1.15 0.723 1.82 -0.213 0.25 0.395 0.4036 0.808 0.495 1.32 PRS_PLINK_2.51188643150958e.06 FALSE 962.2 Insulins and antidiabetic agents causing adverse effects in therapeutic use Both 36 119 18 injuries & poisonings gray50 119, 36 30, 12 30, 10 29, 8 30, 6 -0.163 0.232 0.483 0.3165 0.85 0.539 1.34 -0.0287 0.529 0.957 0.01919 0.972 0.345 2.74 -0.49 0.583 0.4 0.3979 0.612 0.195 1.92 0.0423 0.661 0.949 0.02271 1.04 0.285 3.81 PRS_PLINK_2.51188643150958e.06 TRUE 962.3 Hormones and synthetic substitutes causing adverse effects in therapeutic use Both 204 659 18 injuries & poisonings gray50 659, 204 165, 66 165, 45 164, 43 165, 50 -0.0747 0.0792 0.345 0.4619 0.928 0.795 1.08 -0.368 0.225 0.101 0.9955 0.692 0.446 1.07 -0.413 0.229 0.0716 1.145 0.662 0.422 1.04 -0.223 0.223 0.317 0.4987 0.8 0.517 1.24 PRS_PLINK_2.51188643150958e.06 FALSE 963 Poisoning by primarily systemic agents Both 744 3085 18 injuries & poisonings gray50 3085, 744 772, 167 771, 190 771, 212 771, 175 0.0713 0.0429 0.0963 1.016 1.07 0.987 1.17 0.16 0.118 0.176 0.7542 1.17 0.931 1.48 0.247 0.116 0.0335 1.475 1.28 1.02 1.61 0.0485 0.12 0.686 0.1636 1.05 0.83 1.33 PRS_PLINK_2.51188643150958e.06 FALSE 963.1 Antineoplastic and immunosuppressive drugs causing adverse effects Both 715 3022 18 injuries & poisonings gray50 3022, 715 756, 160 755, 182 755, 204 756, 169 0.07 0.0437 0.109 0.9629 1.07 0.985 1.17 0.159 0.121 0.188 0.7253 1.17 0.925 1.48 0.251 0.119 0.0344 1.463 1.28 1.02 1.62 0.047 0.122 0.701 0.1544 1.05 0.825 1.33 PRS_PLINK_2.51188643150958e.06 FALSE 964 Poisoning by agents primarily affecting blood constituents Both 366 1000 18 injuries & poisonings gray50 1000, 366 250, 102 250, 70 250, 107 250, 87 0.00555 0.0617 0.928 0.03225 1.01 0.891 1.13 -0.303 0.182 0.0955 1.02 0.739 0.517 1.05 0.0819 0.168 0.626 0.2034 1.09 0.781 1.51 -0.136 0.173 0.433 0.3635 0.873 0.622 1.23 PRS_PLINK_2.51188643150958e.06 FALSE 964.1 Anticoagulants causing adverse effects Both 348 958 18 injuries & poisonings gray50 958, 348 240, 93 239, 74 239, 105 240, 76 -0.00852 0.0617 0.89 0.05057 0.992 0.879 1.12 -0.148 0.184 0.421 0.3759 0.863 0.602 1.24 0.153 0.172 0.374 0.4274 1.17 0.832 1.63 -0.172 0.182 0.343 0.4652 0.842 0.59 1.2 PRS_PLINK_2.51188643150958e.06 FALSE 965 Poisoning by analgesics, antipyretics, and antirheumatics Both 328 1111 18 injuries & poisonings gray50 1111, 328 278, 92 278, 77 277, 97 278, 62 -0.0859 0.061 0.159 0.7988 0.918 0.814 1.03 -0.128 0.179 0.474 0.3244 0.88 0.619 1.25 0.109 0.173 0.527 0.2785 1.12 0.795 1.56 -0.368 0.189 0.0519 1.284 0.692 0.478 1 PRS_PLINK_2.51188643150958e.06 FALSE 965.1 Opiates and related narcotics causing adverse effects in therapeutic use Both 548 1903 18 injuries & poisonings gray50 1903, 548 476, 157 476, 126 475, 150 476, 115 -0.0561 0.0464 0.227 0.6436 0.945 0.863 1.04 -0.186 0.137 0.175 0.7574 0.83 0.635 1.09 -0.0378 0.133 0.776 0.1102 0.963 0.742 1.25 -0.341 0.141 0.0153 1.814 0.711 0.54 0.937 PRS_PLINK_2.51188643150958e.06 FALSE 965.3 Salicylates causing adverse effects in therapeutic use Both 30 146 18 injuries & poisonings gray50 146, 30 37, 13 36, 9 36, 4 37, 4 -0.371 0.22 0.0925 1.034 0.69 0.448 1.06 -0.453 0.521 0.384 0.4154 0.636 0.229 1.76 -1.18 0.619 0.0575 1.24 0.309 0.0919 1.04 -1.27 0.674 0.0596 1.225 0.281 0.0748 1.05 PRS_PLINK_2.51188643150958e.06 TRUE 966 Poisoning by anticonvulsants and anti-Parkinsonism drugs Both 46 128 18 injuries & poisonings gray50 128, 46 32, 12 32, 10 32, 16 32, 8 -0.0101 0.179 0.955 0.01997 0.99 0.697 1.41 -0.0339 0.527 0.949 0.02289 0.967 0.344 2.71 -0.0858 0.534 0.872 0.0593 0.918 0.322 2.61 -0.224 0.582 0.701 0.1545 0.799 0.255 2.5 PRS_PLINK_2.51188643150958e.06 TRUE 967 Adverse effects of sedatives or other central nervous system depressants and anesthetics Both 378 1606 18 injuries & poisonings gray50 1606, 378 402, 86 401, 104 401, 106 402, 82 0.0271 0.056 0.628 0.2021 1.03 0.921 1.15 0.206 0.163 0.206 0.6871 1.23 0.893 1.69 0.204 0.162 0.209 0.6805 1.23 0.892 1.68 -0.0579 0.171 0.735 0.1339 0.944 0.675 1.32 PRS_PLINK_2.51188643150958e.06 FALSE 969 Poisoning by psychotropic agents Both 140 342 18 injuries & poisonings gray50 342, 140 86, 43 85, 27 85, 41 86, 29 -0.098 0.106 0.354 0.4504 0.907 0.737 1.12 -0.497 0.3 0.0977 1.01 0.608 0.338 1.1 -0.0541 0.278 0.846 0.0728 0.947 0.55 1.63 -0.434 0.293 0.139 0.8561 0.648 0.365 1.15 PRS_PLINK_2.51188643150958e.06 FALSE 971 Poisoning by drugs primarily affecting the autonomic nervous system Both 30 106 18 injuries & poisonings gray50 106, 30 27, 7 26, 6 26, 3 27, 14 0.335 0.284 0.238 0.6227 1.4 0.801 2.44 0.00845 0.702 0.99 0.004192 1.01 0.255 3.99 -0.443 0.765 0.563 0.2499 0.642 0.143 2.88 0.839 0.583 0.15 0.8231 2.31 0.738 7.25 PRS_PLINK_2.51188643150958e.06 TRUE 972 Poisoning by agents primarily affecting the cardiovascular system Both 144 419 18 injuries & poisonings gray50 419, 144 105, 43 105, 31 104, 33 105, 36 -0.101 0.0959 0.292 0.5347 0.904 0.749 1.09 -0.345 0.28 0.217 0.6629 0.708 0.409 1.23 -0.313 0.281 0.265 0.5771 0.731 0.422 1.27 -0.192 0.267 0.473 0.3254 0.825 0.489 1.39 PRS_PLINK_2.51188643150958e.06 FALSE 972.1 Cardiac rhythm regulators causing adverse effects in therapeutic use Both 38 107 18 injuries & poisonings gray50 107, 38 27, 11 27, 12 26, 5 27, 9 -0.198 0.175 0.259 0.5867 0.82 0.582 1.16 -0.191 0.559 0.733 0.1351 0.826 0.276 2.47 -0.856 0.63 0.174 0.7589 0.425 0.124 1.46 -0.24 0.565 0.671 0.1733 0.787 0.26 2.38 PRS_PLINK_2.51188643150958e.06 TRUE 972.6 Antihypertensive agents causing adverse effects Both 54 155 18 injuries & poisonings gray50 155, 54 39, 15 39, 13 38, 14 39, 12 -0.145 0.174 0.404 0.3932 0.865 0.616 1.22 -0.151 0.471 0.748 0.126 0.86 0.341 2.16 0.00746 0.473 0.987 0.005497 1.01 0.399 2.55 -0.186 0.48 0.699 0.1555 0.831 0.324 2.13 PRS_PLINK_2.51188643150958e.06 FALSE 974 Poisoning by water, mineral, and uric acid metabolism drugs Both 66 160 18 injuries & poisonings gray50 160, 66 40, 20 40, 15 40, 20 40, 11 -0.0455 0.148 0.758 0.1204 0.956 0.716 1.28 -0.31 0.429 0.469 0.3288 0.733 0.316 1.7 -0.0155 0.411 0.97 0.01329 0.985 0.44 2.21 -0.526 0.442 0.234 0.6308 0.591 0.248 1.41 PRS_PLINK_2.51188643150958e.06 FALSE 975 Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system Both 27 104 18 injuries & poisonings gray50 104, 27 26, 2 26, 6 26, 10 26, 9 0.457 0.253 0.0704 1.153 1.58 0.963 2.59 0.967 0.885 0.275 0.561 2.63 0.464 14.9 1.4 0.808 0.0826 1.083 4.07 0.834 19.8 1.28 0.785 0.103 0.9868 3.6 0.772 16.8 PRS_PLINK_2.51188643150958e.06 TRUE 976 Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs Both 29 96 18 injuries & poisonings gray50 96, 29 24, 11 24, 7 24, 5 24, 6 -0.39 0.194 0.0445 1.352 0.677 0.463 0.99 -0.451 0.597 0.45 0.3466 0.637 0.198 2.05 -0.716 0.688 0.298 0.5256 0.489 0.127 1.88 -0.676 0.647 0.296 0.528 0.509 0.143 1.81 PRS_PLINK_2.51188643150958e.06 TRUE 977 Personal history of allergy to medicinal agents Both 664 2271 18 injuries & poisonings gray50 2271, 664 568, 200 568, 154 567, 171 568, 138 -0.085 0.041 0.0381 1.419 0.919 0.848 0.995 -0.26 0.123 0.0352 1.453 0.771 0.606 0.982 -0.154 0.12 0.201 0.696 0.857 0.677 1.09 -0.372 0.127 0.00336 2.474 0.689 0.538 0.884 PRS_PLINK_2.51188643150958e.06 FALSE 979 Adverse drug events and drug allergies Both 1253 3889 18 injuries & poisonings gray50 3889, 1253 973, 328 972, 307 972, 335 972, 283 0.00719 0.0329 0.827 0.0825 1.01 0.944 1.07 -0.0653 0.0918 0.477 0.3213 0.937 0.782 1.12 0.0246 0.0905 0.786 0.1046 1.02 0.858 1.22 -0.14 0.0938 0.135 0.8688 0.869 0.723 1.04 PRS_PLINK_2.51188643150958e.06 FALSE 980 Encounter for long-term (current) use of antibiotics Both 392 2255 1 infectious diseases blue 2255, 392 563, 104 564, 88 563, 95 564, 105 -0.0367 0.0524 0.484 0.3151 0.964 0.87 1.07 -0.166 0.156 0.288 0.5399 0.847 0.623 1.15 -0.0849 0.155 0.583 0.2343 0.919 0.678 1.24 0.0187 0.151 0.902 0.04487 1.02 0.757 1.37 PRS_PLINK_2.51188643150958e.06 FALSE 985 Toxic effect of other metals Both 29 103 18 injuries & poisonings gray50 103, 29 26, 5 26, 8 25, 7 26, 9 0.119 0.242 0.623 0.2052 1.13 0.701 1.81 0.612 0.648 0.344 0.4631 1.84 0.519 6.56 0.26 0.699 0.709 0.1491 1.3 0.33 5.11 0.411 0.616 0.504 0.2973 1.51 0.451 5.04 PRS_PLINK_2.51188643150958e.06 TRUE 989 Toxic effect of other substances, chiefly nonmedicinal as to source Both 48 232 18 injuries & poisonings gray50 232, 48 58, 8 58, 6 58, 13 58, 21 0.393 0.197 0.0468 1.33 1.48 1.01 2.18 -0.292 0.53 0.582 0.2349 0.747 0.264 2.11 0.281 0.481 0.559 0.2524 1.32 0.516 3.4 1.09 0.469 0.02 1.698 2.98 1.19 7.47 PRS_PLINK_2.51188643150958e.06 TRUE 990 Effects radiation NOS Both 768 4713 18 injuries & poisonings gray50 4713, 768 1178, 207 1178, 182 1178, 200 1178, 179 0.0128 0.0395 0.746 0.1274 1.01 0.937 1.09 -0.121 0.11 0.272 0.5652 0.886 0.714 1.1 -0.0172 0.108 0.873 0.05875 0.983 0.795 1.21 -0.124 0.111 0.263 0.5805 0.883 0.711 1.1 PRS_PLINK_2.51188643150958e.06 FALSE 994 Sepsis and SIRS Both 899 3424 18 injuries & poisonings gray50 3424, 899 855, 238 856, 192 856, 213 856, 256 0.0443 0.0384 0.249 0.6034 1.05 0.969 1.13 -0.201 0.109 0.0645 1.191 0.818 0.661 1.01 -0.085 0.107 0.426 0.3705 0.919 0.745 1.13 0.066 0.103 0.522 0.2825 1.07 0.873 1.31 PRS_PLINK_2.51188643150958e.06 FALSE 994.1 Systemic inflammatory response syndrome (SIRS) Both 122 470 18 injuries & poisonings gray50 470, 122 117, 39 117, 26 117, 24 118, 33 0.0858 0.108 0.429 0.3675 1.09 0.881 1.35 -0.393 0.289 0.173 0.7612 0.675 0.383 1.19 -0.392 0.297 0.187 0.7281 0.676 0.377 1.21 -0.13 0.279 0.641 0.1929 0.878 0.509 1.52 PRS_PLINK_2.51188643150958e.06 FALSE 994.2 Sepsis Both 861 3260 18 injuries & poisonings gray50 3260, 861 814, 226 815, 186 815, 207 815, 242 0.0428 0.0394 0.277 0.557 1.04 0.966 1.13 -0.179 0.111 0.106 0.9737 0.836 0.672 1.04 -0.0659 0.109 0.545 0.2637 0.936 0.756 1.16 0.0645 0.106 0.543 0.2651 1.07 0.866 1.31 PRS_PLINK_2.51188643150958e.06 FALSE 994.21 Septic shock Both 272 940 18 injuries & poisonings gray50 940, 272 235, 68 235, 61 235, 59 235, 84 0.0881 0.0727 0.225 0.647 1.09 0.947 1.26 -0.104 0.201 0.605 0.2179 0.902 0.609 1.34 -0.12 0.202 0.554 0.2567 0.887 0.597 1.32 0.211 0.191 0.268 0.5712 1.24 0.85 1.8 PRS_PLINK_2.51188643150958e.06 FALSE