phewas_code phewas_string sex MatchedCases MatchedControls groupnum group color N N_Q1 N_Q2 N_Q3 N_Q4 PRS_BETA PRS_SEBETA PRS_P PRS_LOG10P PRS_OR PRS_CI1 PRS_CI2 Q1Q2_BETA Q1Q2_SEBETA Q1Q2_P Q1Q2_LOG10P Q1Q2_OR Q1Q2_CI1 Q1Q2_CI2 Q1Q3_BETA Q1Q3_SEBETA Q1Q3_P Q1Q3_LOG10P Q1Q3_OR Q1Q3_CI1 Q1Q3_CI2 Q1Q4_BETA Q1Q4_SEBETA Q1Q4_P Q1Q4_LOG10P Q1Q4_OR Q1Q4_CI1 Q1Q4_CI2 predictor exclude 008 Intestinal infection Both 1484 18516 1 infectious diseases blue 18516, 1484 4629, 331 4629, 391 4629, 397 4629, 365 0.0265 0.0195 0.174 0.7597 1.03 0.988 1.07 0.165 0.0774 0.0327 1.485 1.18 1.01 1.37 0.178 0.0773 0.0215 1.668 1.19 1.03 1.39 0.0908 0.0786 0.248 0.6058 1.1 0.939 1.28 PRS_PLINK_0.001 FALSE 008.5 Bacterial enteritis Both 384 5676 1 infectious diseases blue 5676, 384 1419, 92 1419, 93 1419, 107 1419, 92 0.0417 0.0338 0.218 0.6616 1.04 0.976 1.11 0.00591 0.151 0.969 0.01381 1.01 0.749 1.35 0.16 0.147 0.274 0.5622 1.17 0.881 1.56 -0.0134 0.151 0.929 0.03194 0.987 0.734 1.33 PRS_PLINK_0.001 FALSE 008.52 Intestinal infection due to C. difficile Both 76 1314 1 infectious diseases blue 1314, 76 329, 27 328, 19 328, 11 329, 19 -0.756 0.4 0.0586 1.232 0.47 0.215 1.03 -0.314 0.3 0.296 0.5286 0.731 0.406 1.32 -0.89 0.352 0.0115 1.94 0.411 0.206 0.819 -0.311 0.302 0.303 0.5179 0.733 0.405 1.32 PRS_PLINK_0.001 FALSE 008.6 Viral Enteritis Both 142 1798 1 infectious diseases blue 1798, 142 450, 35 449, 35 449, 37 450, 35 0.0754 0.058 0.193 0.7142 1.08 0.963 1.21 -0.0174 0.246 0.944 0.02518 0.983 0.607 1.59 0.0383 0.241 0.874 0.05868 1.04 0.648 1.66 -0.00892 0.245 0.971 0.01282 0.991 0.614 1.6 PRS_PLINK_0.001 FALSE 008.7 Intestinal infection due to protozoa Both 6 136 1 infectious diseases blue 136, 6 34, 0 34, 3 34, 2 34, 1 1.97 1.12 0.078 1.108 7.17 0.802 64.2 2.15 1.2 0.0731 1.136 8.58 0.817 90.1 1.13 1.08 0.296 0.5291 3.1 0.372 25.9 0.822 1.18 0.485 0.3139 2.28 0.226 22.9 PRS_PLINK_0.001 TRUE 010 Tuberculosis Both 22 333 1 infectious diseases blue 333, 22 84, 5 83, 9 83, 3 83, 5 -0.224 0.684 0.743 0.1287 0.799 0.209 3.05 0.641 0.547 0.241 0.6176 1.9 0.65 5.55 -0.541 0.656 0.41 0.3874 0.582 0.161 2.11 -0.37 0.617 0.549 0.2607 0.691 0.206 2.32 PRS_PLINK_0.001 TRUE 038 Septicemia Both 657 8677 1 infectious diseases blue 8677, 657 2170, 162 2169, 167 2169, 158 2169, 170 -0.0523 0.0636 0.41 0.387 0.949 0.838 1.07 0.0281 0.114 0.805 0.09395 1.03 0.822 1.29 -0.0287 0.115 0.803 0.09502 0.972 0.775 1.22 0.0427 0.114 0.707 0.1507 1.04 0.835 1.3 PRS_PLINK_0.001 FALSE 038.1 Gram negative septicemia Both 141 1787 1 infectious diseases blue 1787, 141 447, 40 447, 36 446, 38 447, 27 -0.3 0.288 0.297 0.5271 0.741 0.421 1.3 -0.127 0.236 0.59 0.2293 0.88 0.554 1.4 -0.0212 0.234 0.928 0.03255 0.979 0.619 1.55 -0.419 0.255 0.0997 1.001 0.657 0.399 1.08 PRS_PLINK_0.001 FALSE 038.2 Gram positive septicemia Both 65 1075 1 infectious diseases blue 1075, 65 269, 17 269, 14 268, 20 269, 14 -0.297 0.429 0.488 0.3117 0.743 0.321 1.72 -0.243 0.355 0.493 0.3069 0.784 0.391 1.57 0.0833 0.331 0.801 0.09613 1.09 0.568 2.08 -0.238 0.357 0.504 0.2972 0.788 0.392 1.59 PRS_PLINK_0.001 FALSE 041 Bacterial infection NOS Both 1878 25433 1 infectious diseases blue 25433, 1878 6358, 452 6358, 478 6358, 484 6358, 464 -0.0112 0.0252 0.655 0.1835 0.989 0.941 1.04 0.0567 0.0679 0.403 0.3943 1.06 0.927 1.21 0.0699 0.0677 0.302 0.5206 1.07 0.939 1.22 0.027 0.0683 0.693 0.1595 1.03 0.899 1.17 PRS_PLINK_0.001 FALSE 041.1 Staphylococcus infections Both 474 6710 1 infectious diseases blue 6710, 474 1678, 119 1677, 119 1677, 127 1678, 109 0.0402 0.0396 0.31 0.509 1.04 0.963 1.13 -0.000772 0.133 0.995 0.002012 0.999 0.769 1.3 0.0625 0.131 0.634 0.1978 1.06 0.823 1.38 -0.0788 0.136 0.563 0.2496 0.924 0.708 1.21 PRS_PLINK_0.001 FALSE 041.2 Streptococcus infection Both 285 3572 1 infectious diseases blue 3572, 285 893, 70 893, 78 893, 68 893, 69 -0.0101 0.0714 0.888 0.05164 0.99 0.861 1.14 0.109 0.17 0.519 0.285 1.12 0.8 1.56 -0.0307 0.175 0.86 0.06534 0.97 0.689 1.37 -0.0233 0.174 0.894 0.04879 0.977 0.694 1.38 PRS_PLINK_0.001 FALSE 041.4 E. coli Both 412 5595 1 infectious diseases blue 5595, 412 1398, 90 1399, 118 1398, 106 1399, 98 0.00722 0.0421 0.864 0.06357 1.01 0.927 1.09 0.271 0.144 0.0596 1.225 1.31 0.989 1.74 0.176 0.147 0.231 0.6359 1.19 0.894 1.59 0.0845 0.15 0.573 0.2421 1.09 0.811 1.46 PRS_PLINK_0.001 FALSE 053 Herpes zoster Both 68 806 1 infectious diseases blue 806, 68 202, 18 201, 19 201, 11 202, 20 0.048 0.127 0.704 0.1521 1.05 0.819 1.34 0.0613 0.338 0.856 0.06743 1.06 0.548 2.06 -0.456 0.379 0.229 0.6393 0.634 0.301 1.33 0.114 0.329 0.729 0.1374 1.12 0.588 2.13 PRS_PLINK_0.001 FALSE 053.1 Herpes zoster with nervous system complications Both 18 179 1 infectious diseases blue 179, 18 45, 3 45, 5 44, 2 45, 8 0.0753 0.12 0.53 0.2757 1.08 0.852 1.36 0.736 0.718 0.305 0.5159 2.09 0.512 8.52 -8.62e-05 0.896 1 3.335e-05 1 0.173 5.79 1.01 0.656 0.124 0.9051 2.74 0.757 9.91 PRS_PLINK_0.001 TRUE 054 Herpes simplex Both 35 463 1 infectious diseases blue 463, 35 116, 6 116, 9 115, 11 116, 9 0.0747 0.117 0.524 0.2807 1.08 0.856 1.36 0.373 0.503 0.457 0.3396 1.45 0.542 3.89 0.536 0.489 0.272 0.565 1.71 0.656 4.45 0.4 0.494 0.418 0.3785 1.49 0.567 3.93 PRS_PLINK_0.001 TRUE 070 Viral hepatitis Both 112 1244 1 infectious diseases blue 1244, 112 311, 27 311, 29 311, 27 311, 29 0.0579 0.117 0.62 0.2076 1.06 0.843 1.33 0.0701 0.275 0.799 0.09756 1.07 0.626 1.84 0.0087 0.282 0.975 0.01082 1.01 0.58 1.75 0.143 0.277 0.606 0.2178 1.15 0.671 1.98 PRS_PLINK_0.001 FALSE 070.1 Viral hepatitis A Both 13 152 1 infectious diseases blue 152, 13 38, 2 38, 1 38, 2 38, 8 3.18 1.21 0.00871 2.06 24.2 2.24 261 0.654 1.08 0.546 0.2626 1.92 0.23 16.1 -0.0896 0.919 0.922 0.03512 0.914 0.151 5.54 2.19 0.985 0.0261 1.584 8.95 1.3 61.7 PRS_PLINK_0.001 TRUE 070.2 Viral hepatitis B Both 28 272 1 infectious diseases blue 272, 28 68, 9 68, 7 68, 2 68, 10 0.41 0.677 0.544 0.2641 1.51 0.4 5.68 -0.559 0.534 0.296 0.5291 0.572 0.201 1.63 -1.2 0.683 0.0785 1.105 0.3 0.0787 1.15 -0.0367 0.48 0.939 0.0273 0.964 0.376 2.47 PRS_PLINK_0.001 TRUE 070.3 Viral hepatitis C Both 45 539 1 infectious diseases blue 539, 45 135, 12 135, 16 134, 10 135, 7 -0.826 0.556 0.138 0.8606 0.438 0.147 1.3 0.258 0.388 0.506 0.2954 1.29 0.605 2.77 -0.198 0.426 0.642 0.1923 0.82 0.356 1.89 -0.449 0.463 0.332 0.4786 0.638 0.257 1.58 PRS_PLINK_0.001 TRUE 070.4 Chronic hepatitis Both 50 593 1 infectious diseases blue 593, 50 149, 7 148, 10 148, 15 148, 18 0.0977 0.109 0.37 0.4322 1.1 0.891 1.36 0.288 0.474 0.543 0.265 1.33 0.527 3.38 0.686 0.442 0.121 0.918 1.99 0.835 4.73 0.915 0.434 0.0351 1.454 2.5 1.07 5.85 PRS_PLINK_0.001 TRUE 070.9 Hepatitis NOS Both 76 839 1 infectious diseases blue 839, 76 210, 15 210, 20 209, 13 210, 28 0.0521 0.0781 0.505 0.2969 1.05 0.904 1.23 0.302 0.343 0.378 0.4228 1.35 0.691 2.65 -0.185 0.374 0.621 0.2072 0.831 0.399 1.73 0.579 0.329 0.0786 1.104 1.78 0.936 3.4 PRS_PLINK_0.001 FALSE 071 Human immunodeficiency virus [HIV] disease Both 36 324 1 infectious diseases blue 324, 36 81, 10 81, 9 81, 12 81, 5 -0.616 0.626 0.325 0.4882 0.54 0.159 1.84 -0.187 0.484 0.699 0.1556 0.829 0.321 2.14 0.181 0.451 0.688 0.1625 1.2 0.495 2.9 -0.868 0.561 0.122 0.9144 0.42 0.14 1.26 PRS_PLINK_0.001 TRUE 071.1 HIV infection, symptomatic Both 27 259 1 infectious diseases blue 259, 27 65, 6 65, 5 64, 11 65, 5 0.17 0.691 0.806 0.09358 1.18 0.306 4.59 -0.469 0.615 0.446 0.3506 0.626 0.187 2.09 PRS_PLINK_0.001 TRUE 078 Viral warts & HPV Both 174 2260 1 infectious diseases blue 2260, 174 565, 35 565, 55 565, 48 565, 36 0.0319 0.047 0.497 0.3039 1.03 0.942 1.13 0.459 0.221 0.0374 1.428 1.58 1.03 2.44 0.341 0.227 0.132 0.8791 1.41 0.902 2.19 0.0397 0.24 0.868 0.06126 1.04 0.65 1.66 PRS_PLINK_0.001 FALSE 079 Viral infection Both 519 5934 1 infectious diseases blue 5934, 519 1484, 118 1483, 142 1483, 124 1484, 135 0.0809 0.0296 0.00626 2.203 1.08 1.02 1.15 0.181 0.129 0.16 0.7959 1.2 0.931 1.54 0.0566 0.133 0.671 0.1735 1.06 0.815 1.37 0.135 0.131 0.302 0.5202 1.14 0.886 1.48 PRS_PLINK_0.001 FALSE 079.1 Varicella infection Both 11 143 1 infectious diseases blue 143, 11 36, 2 36, 3 35, 3 36, 3 1.13 1.14 0.321 0.4936 3.09 0.333 28.7 0.753 0.92 0.413 0.3839 2.12 0.35 12.9 0.353 0.813 0.664 0.178 1.42 0.289 7.01 0.212 0.773 0.783 0.106 1.24 0.272 5.62 PRS_PLINK_0.001 TRUE 080 Postoperative infection Both 743 9572 1 infectious diseases blue 9572, 743 2393, 196 2393, 161 2393, 197 2393, 189 -0.00682 0.038 0.858 0.06672 0.993 0.922 1.07 -0.2 0.11 0.0689 1.161 0.819 0.661 1.02 0.00402 0.105 0.969 0.01351 1 0.818 1.23 -0.0339 0.106 0.748 0.1261 0.967 0.786 1.19 PRS_PLINK_0.001 FALSE 081 Infection/inflammation of internal prosthetic device; implant; and graft Both 376 5276 1 infectious diseases blue 5276, 376 1319, 102 1319, 93 1319, 97 1319, 84 0.00555 0.0468 0.906 0.04306 1.01 0.917 1.1 -0.106 0.148 0.474 0.3247 0.9 0.673 1.2 -0.0531 0.146 0.716 0.145 0.948 0.712 1.26 -0.201 0.151 0.184 0.7346 0.818 0.608 1.1 PRS_PLINK_0.001 FALSE 090 Sexually transmitted infections (not HIV or hepatitis) Both 11 157 1 infectious diseases blue 157, 11 40, 5 39, 2 39, 3 39, 1 -0.197 0.536 0.713 0.1471 0.821 0.287 2.35 -0.573 0.746 0.442 0.3547 0.564 0.131 2.43 -0.293 0.71 0.68 0.1676 0.746 0.185 3 -1.23 0.829 0.137 0.8642 0.291 0.0574 1.48 PRS_PLINK_0.001 TRUE 110 Dermatophytosis / Dermatomycosis Both 53 596 1 infectious diseases blue 596, 53 149, 16 149, 14 149, 13 149, 10 -0.525 0.486 0.279 0.554 0.591 0.228 1.53 -0.18 0.379 0.635 0.1971 0.836 0.398 1.76 -0.167 0.378 0.659 0.1812 0.846 0.403 1.78 -0.463 0.403 0.251 0.6008 0.629 0.285 1.39 PRS_PLINK_0.001 FALSE 110.1 Dermatophytosis Both 52 585 1 infectious diseases blue 585, 52 147, 16 146, 14 146, 12 146, 10 -0.516 0.481 0.284 0.5464 0.597 0.232 1.53 -0.199 0.38 0.6 0.2216 0.819 0.389 1.73 -0.235 0.387 0.543 0.2654 0.79 0.37 1.69 -0.446 0.405 0.271 0.5666 0.64 0.289 1.42 PRS_PLINK_0.001 FALSE 110.11 Dermatophytosis of nail Both 15 180 1 infectious diseases blue 180, 15 45, 4 45, 3 45, 4 45, 4 0.339 0.84 0.686 0.1634 1.4 0.27 7.29 -0.694 0.76 0.362 0.4417 0.5 0.113 2.22 -0.173 0.758 0.819 0.08662 0.841 0.19 3.72 0.0663 0.662 0.92 0.03611 1.07 0.292 3.91 PRS_PLINK_0.001 TRUE 110.12 Althete's foot Both 29 280 1 infectious diseases blue 280, 29 70, 9 70, 9 70, 7 70, 4 -0.679 0.645 0.292 0.5346 0.507 0.143 1.79 -0.0451 0.485 0.926 0.03345 0.956 0.369 2.47 -0.0804 0.517 0.877 0.05724 0.923 0.335 2.54 -0.617 0.576 0.285 0.5458 0.54 0.174 1.67 PRS_PLINK_0.001 TRUE 112 Candidiasis Both 337 4463 1 infectious diseases blue 4463, 337 1116, 77 1116, 86 1115, 94 1116, 80 0.0208 0.0432 0.631 0.2003 1.02 0.938 1.11 0.122 0.161 0.448 0.3484 1.13 0.824 1.55 0.206 0.158 0.192 0.7174 1.23 0.902 1.68 0.0366 0.164 0.823 0.08466 1.04 0.753 1.43 PRS_PLINK_0.001 FALSE 117 Mycoses Both 41 619 1 infectious diseases blue 619, 41 155, 13 155, 4 154, 11 155, 13 0.274 0.519 0.598 0.2231 1.31 0.475 3.64 -1.06 0.522 0.0418 1.378 0.346 0.124 0.962 -0.176 0.405 0.664 0.1781 0.838 0.379 1.86 -0.0151 0.391 0.969 0.01355 0.985 0.458 2.12 PRS_PLINK_0.001 TRUE 117.4 Aspergillosis Both 20 351 1 infectious diseases blue 351, 20 88, 8 88, 2 87, 5 88, 5 -0.469 0.69 0.497 0.3037 0.626 0.162 2.42 -1.23 0.685 0.072 1.143 0.292 0.0761 1.12 -0.339 0.538 0.528 0.2774 0.712 0.248 2.04 -0.423 0.541 0.434 0.3622 0.655 0.227 1.89 PRS_PLINK_0.001 TRUE 130 Spirochetal infection Both 15 159 1 infectious diseases blue 159, 15 40, 4 40, 2 39, 5 40, 4 0.0435 0.122 0.722 0.1413 1.04 0.822 1.33 -0.133 0.832 0.873 0.05901 0.875 0.171 4.47 0.0283 0.657 0.966 0.01521 1.03 0.284 3.73 0.0325 0.69 0.962 0.01661 1.03 0.267 4 PRS_PLINK_0.001 TRUE 133 Arthropod-borne diseases Both 19 154 1 infectious diseases blue 154, 19 39, 1 38, 7 38, 2 39, 9 0.789 0.853 0.355 0.45 2.2 0.414 11.7 1.42 0.847 0.0943 1.025 4.12 0.784 21.7 0.513 0.886 0.562 0.2499 1.67 0.294 9.48 1.87 0.863 0.0305 1.516 6.47 1.19 35.1 PRS_PLINK_0.001 TRUE 134 Helminthiases Both 21 272 1 infectious diseases blue 272, 21 68, 4 68, 4 68, 9 68, 4 0.0767 0.118 0.517 0.2864 1.08 0.856 1.36 -0.12 0.661 0.856 0.06739 0.887 0.243 3.24 0.528 0.6 0.379 0.4213 1.69 0.523 5.49 0.101 0.648 0.877 0.05716 1.11 0.311 3.94 PRS_PLINK_0.001 TRUE 134.1 Intestinal helminthiases Both 17 229 1 infectious diseases blue 229, 17 58, 4 57, 3 57, 7 57, 3 0.141 0.813 0.862 0.0644 1.15 0.234 5.67 -0.446 0.726 0.539 0.2684 0.64 0.154 2.65 0.297 0.637 0.641 0.1932 1.35 0.386 4.69 -0.0673 0.702 0.924 0.0345 0.935 0.236 3.7 PRS_PLINK_0.001 TRUE 136 Other infectious and parasitic diseases Both 41 400 1 infectious diseases blue 400, 41 100, 15 100, 12 100, 6 100, 8 -0.928 0.599 0.121 0.917 0.395 0.122 1.28 -0.184 0.402 0.648 0.1888 0.832 0.378 1.83 -1.2 0.507 0.0179 1.747 0.301 0.111 0.813 -0.719 0.459 0.118 0.9296 0.487 0.198 1.2 PRS_PLINK_0.001 TRUE 145 Cancer of mouth Both 114 1396 2 neoplasms darkcyan 1396, 114 349, 33 349, 28 349, 32 349, 21 -0.00589 0.0971 0.952 0.02152 0.994 0.822 1.2 -0.191 0.264 0.469 0.329 0.826 0.492 1.39 -0.0678 0.256 0.791 0.1017 0.934 0.566 1.54 -0.435 0.283 0.124 0.9071 0.647 0.372 1.13 PRS_PLINK_0.001 FALSE 145.2 Cancer of tongue Both 53 664 2 neoplasms darkcyan 664, 53 166, 17 166, 14 166, 11 166, 11 -0.503 0.48 0.294 0.5311 0.604 0.236 1.55 -0.205 0.372 0.582 0.2353 0.815 0.393 1.69 -0.461 0.386 0.233 0.6323 0.631 0.296 1.35 -0.427 0.387 0.27 0.5689 0.653 0.306 1.39 PRS_PLINK_0.001 FALSE 145.3 Cancer of major salivary glands Both 23 248 2 neoplasms darkcyan 248, 23 62, 5 62, 9 62, 7 62, 2 -0.737 0.717 0.304 0.517 0.478 0.117 1.95 0.679 0.568 0.232 0.6343 1.97 0.648 6 0.378 0.588 0.521 0.2831 1.46 0.46 4.62 -0.603 0.717 0.4 0.3979 0.547 0.134 2.23 PRS_PLINK_0.001 TRUE 145.5 Cancer of the mouth floor Both 5 123 2 neoplasms darkcyan 123, 5 31, 3 31, 0 30, 0 31, 2 0.533 1.07 0.62 0.2077 1.7 0.207 14 -1.9 1.31 0.146 0.8348 0.15 0.0116 1.94 -1.55 1.21 0.202 0.6947 0.213 0.0198 2.29 -0.546 0.852 0.522 0.2827 0.579 0.109 3.08 PRS_PLINK_0.001 TRUE 149 Cancer of larynx, pharynx, nasal cavities Both 95 1319 2 neoplasms darkcyan 1319, 95 330, 20 330, 30 329, 19 330, 26 0.0488 0.093 0.6 0.222 1.05 0.875 1.26 0.413 0.291 0.156 0.8076 1.51 0.855 2.67 0.0495 0.321 0.878 0.0567 1.05 0.56 1.97 0.305 0.3 0.309 0.5099 1.36 0.754 2.44 PRS_PLINK_0.001 FALSE 149.1 Cancer of oropharynx Both 44 534 2 neoplasms darkcyan 534, 44 134, 9 133, 10 133, 7 134, 18 0.136 0.113 0.23 0.6389 1.15 0.918 1.43 0.334 0.471 0.479 0.3201 1.4 0.555 3.51 -0.111 0.498 0.824 0.08428 0.895 0.337 2.38 0.76 0.42 0.0702 1.153 2.14 0.939 4.87 PRS_PLINK_0.001 TRUE 149.4 Cancer of larynx Both 28 527 2 neoplasms darkcyan 527, 28 132, 9 132, 7 131, 5 132, 7 -0.16 0.42 0.704 0.1524 0.852 0.374 1.94 -0.29 0.484 0.548 0.261 0.748 0.29 1.93 -0.609 0.518 0.239 0.6208 0.544 0.197 1.5 -0.337 0.49 0.491 0.3087 0.714 0.273 1.86 PRS_PLINK_0.001 TRUE 149.9 Cancer of of nasal cavities Both 12 123 2 neoplasms darkcyan 123, 12 31, 4 31, 4 30, 3 31, 1 0.0372 0.706 0.958 0.01866 1.04 0.26 4.14 -0.341 0.812 0.674 0.1713 0.711 0.145 3.49 -0.833 0.904 0.357 0.4477 0.435 0.0739 2.56 PRS_PLINK_0.001 TRUE 150 Cancer of esophagus Both 107 1586 2 neoplasms darkcyan 1586, 107 397, 20 396, 22 396, 37 397, 28 0.0565 0.0778 0.468 0.3298 1.06 0.908 1.23 0.0583 0.307 0.849 0.07108 1.06 0.581 1.93 0.64 0.28 0.0222 1.654 1.9 1.1 3.28 0.352 0.293 0.229 0.6404 1.42 0.801 2.52 PRS_PLINK_0.001 FALSE 151 Cancer of stomach Both 76 1147 2 neoplasms darkcyan 1147, 76 287, 19 287, 15 286, 19 287, 23 0.0713 0.0909 0.433 0.3634 1.07 0.899 1.28 -0.248 0.341 0.467 0.3306 0.78 0.4 1.52 0.0276 0.323 0.932 0.03056 1.03 0.545 1.94 0.188 0.31 0.545 0.2639 1.21 0.658 2.21 PRS_PLINK_0.001 FALSE 153 Colorectal cancer Both 801 9343 2 neoplasms darkcyan 9343, 801 2336, 218 2336, 192 2335, 205 2336, 186 -0.0684 0.0641 0.286 0.5442 0.934 0.824 1.06 -0.131 0.103 0.202 0.6949 0.877 0.717 1.07 -0.0609 0.101 0.548 0.2612 0.941 0.771 1.15 -0.163 0.104 0.115 0.9385 0.849 0.693 1.04 PRS_PLINK_0.001 FALSE 153.2 Colon cancer Both 528 6216 2 neoplasms darkcyan 6216, 528 1554, 148 1554, 121 1554, 139 1554, 120 -0.0489 0.0679 0.472 0.3261 0.952 0.834 1.09 -0.203 0.127 0.111 0.9555 0.817 0.637 1.05 -0.0645 0.123 0.6 0.2218 0.938 0.737 1.19 -0.212 0.127 0.0969 1.014 0.809 0.63 1.04 PRS_PLINK_0.001 FALSE 153.3 Malignant neoplasm of rectum, rectosigmoid junction, and anus Both 393 4520 2 neoplasms darkcyan 4520, 393 1130, 100 1130, 96 1130, 103 1130, 94 -0.0233 0.0632 0.712 0.1475 0.977 0.863 1.11 -0.0517 0.148 0.727 0.1386 0.95 0.711 1.27 0.035 0.146 0.811 0.09124 1.04 0.778 1.38 -0.0601 0.149 0.686 0.1638 0.942 0.704 1.26 PRS_PLINK_0.001 FALSE 155 Cancer of liver and intrahepatic bile duct Both 61 810 2 neoplasms darkcyan 810, 61 203, 15 202, 17 202, 17 203, 12 -0.421 0.464 0.364 0.4394 0.656 0.264 1.63 0.0708 0.354 0.842 0.0749 1.07 0.536 2.15 0.0935 0.354 0.792 0.1013 1.1 0.548 2.2 -0.265 0.384 0.49 0.3102 0.767 0.361 1.63 PRS_PLINK_0.001 FALSE 155.1 Malignant neoplasm of liver, primary Both 24 318 2 neoplasms darkcyan 318, 24 80, 6 79, 8 79, 4 80, 6 -0.536 0.713 0.452 0.3448 0.585 0.145 2.37 0.236 0.533 0.658 0.1821 1.27 0.446 3.6 -0.34 0.589 0.564 0.2487 0.712 0.225 2.26 -0.135 0.565 0.812 0.09062 0.874 0.289 2.65 PRS_PLINK_0.001 TRUE 157 Pancreatic cancer Both 89 1238 2 neoplasms darkcyan 1238, 89 310, 21 309, 16 309, 20 310, 32 0.0232 0.0627 0.712 0.1477 1.02 0.905 1.16 -0.235 0.329 0.476 0.3225 0.791 0.415 1.51 -0.0622 0.312 0.842 0.07482 0.94 0.51 1.73 0.389 0.286 0.173 0.7608 1.48 0.843 2.58 PRS_PLINK_0.001 FALSE 158 Neoplasm of unspecified nature of digestive system Both 201 2188 2 neoplasms darkcyan 2188, 201 547, 51 547, 40 547, 64 547, 46 0.0195 0.104 0.852 0.06981 1.02 0.832 1.25 -0.239 0.216 0.269 0.5698 0.787 0.515 1.2 0.204 0.196 0.298 0.5254 1.23 0.835 1.8 -0.101 0.209 0.629 0.2011 0.904 0.6 1.36 PRS_PLINK_0.001 FALSE 159 Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum Both 998 11347 2 neoplasms darkcyan 11347, 998 2837, 267 2837, 243 2836, 257 2837, 231 -0.00994 0.0314 0.751 0.1242 0.99 0.931 1.05 -0.0926 0.0924 0.316 0.4997 0.912 0.761 1.09 -0.0391 0.0912 0.668 0.175 0.962 0.804 1.15 -0.146 0.0935 0.12 0.9224 0.865 0.72 1.04 PRS_PLINK_0.001 FALSE 159.2 Malignant neoplasm of small intestine, including duodenum Both 35 387 2 neoplasms darkcyan 387, 35 97, 7 97, 10 96, 8 97, 10 0.275 0.612 0.653 0.1852 1.32 0.397 4.37 0.521 0.514 0.311 0.5071 1.68 0.614 4.61 0.118 0.504 0.815 0.0889 1.13 0.419 3.02 0.498 0.507 0.327 0.4859 1.65 0.608 4.45 PRS_PLINK_0.001 TRUE 159.3 Malignant neoplasm of gallbladder and extrahepatic bile ducts Both 33 422 2 neoplasms darkcyan 422, 33 106, 8 105, 8 105, 11 106, 6 0.00761 0.108 0.944 0.0251 1.01 0.815 1.25 0.201 0.49 0.682 0.166 1.22 0.467 3.2 0.424 0.469 0.365 0.4375 1.53 0.61 3.83 -0.236 0.516 0.647 0.1889 0.79 0.287 2.17 PRS_PLINK_0.001 TRUE 159.4 Malignant neoplasm of retroperitoneum and peritoneum Both 28 404 2 neoplasms darkcyan 404, 28 101, 9 101, 9 101, 4 101, 6 -0.463 0.657 0.48 0.3184 0.629 0.174 2.28 -0.00479 0.461 0.992 0.003618 0.995 0.403 2.46 -0.691 0.574 0.229 0.6409 0.501 0.163 1.54 -0.376 0.509 0.459 0.3378 0.686 0.253 1.86 PRS_PLINK_0.001 TRUE 164 Cancer of intrathoracic organs Both 14 136 2 neoplasms darkcyan 136, 14 34, 2 34, 5 34, 5 34, 2 0.187 1.01 0.853 0.0693 1.21 0.168 8.67 0.793 0.799 0.321 0.4934 2.21 0.461 10.6 0.579 0.862 0.502 0.2996 1.78 0.33 9.66 2.64 1.5 0.0777 1.109 14 0.746 262 PRS_PLINK_0.001 TRUE 165 Cancer within the respiratory system Both 358 5540 2 neoplasms darkcyan 5540, 358 1385, 76 1385, 102 1385, 88 1385, 92 -0.0108 0.0584 0.853 0.06885 0.989 0.882 1.11 0.297 0.155 0.0551 1.259 1.35 0.994 1.82 0.146 0.16 0.361 0.4425 1.16 0.846 1.58 0.195 0.158 0.218 0.6609 1.21 0.891 1.66 PRS_PLINK_0.001 FALSE 165.1 Cancer of bronchus; lung Both 256 4386 2 neoplasms darkcyan 4386, 256 1097, 51 1096, 74 1096, 64 1097, 67 0.012 0.0623 0.847 0.072 1.01 0.896 1.14 0.377 0.185 0.0413 1.384 1.46 1.01 2.09 0.224 0.19 0.238 0.6236 1.25 0.862 1.82 0.279 0.188 0.138 0.8604 1.32 0.914 1.91 PRS_PLINK_0.001 FALSE 170 Cancer of bone and connective tissue Both 90 929 2 neoplasms darkcyan 929, 90 233, 32 232, 19 232, 19 232, 20 0.0264 0.112 0.814 0.08936 1.03 0.824 1.28 -0.451 0.297 0.13 0.8872 0.637 0.356 1.14 -0.518 0.299 0.0834 1.079 0.596 0.331 1.07 -0.433 0.296 0.143 0.8457 0.648 0.363 1.16 PRS_PLINK_0.001 FALSE 170.1 Bone cancer Both 29 285 2 neoplasms darkcyan 285, 29 72, 9 71, 12 71, 5 71, 3 -0.743 0.621 0.231 0.6357 0.476 0.141 1.61 0.29 0.459 0.528 0.2775 1.34 0.544 3.28 -0.396 0.554 0.475 0.3232 0.673 0.227 1.99 -0.879 0.602 0.145 0.8397 0.415 0.128 1.35 PRS_PLINK_0.001 TRUE 170.2 Cancer of connective tissue Both 67 711 2 neoplasms darkcyan 711, 67 178, 23 178, 10 177, 17 178, 17 0.0601 0.102 0.555 0.2557 1.06 0.87 1.3 -0.766 0.378 0.0426 1.371 0.465 0.222 0.975 -0.335 0.335 0.318 0.4981 0.715 0.371 1.38 -0.284 0.334 0.396 0.4025 0.753 0.391 1.45 PRS_PLINK_0.001 FALSE 172 Skin cancer Both 2845 27751 2 neoplasms darkcyan 27751, 2845 6938, 753 6938, 686 6937, 713 6938, 693 0.00449 0.0178 0.801 0.0963 1 0.97 1.04 -0.0907 0.0554 0.102 0.9915 0.913 0.819 1.02 -0.0573 0.0549 0.297 0.5269 0.944 0.848 1.05 -0.0819 0.0553 0.139 0.8583 0.921 0.827 1.03 PRS_PLINK_0.001 FALSE 172.1 Melanomas of skin, dx or hx Both 567 5530 2 neoplasms darkcyan 5530, 567 1383, 141 1382, 144 1382, 131 1383, 151 -0.0395 0.0577 0.493 0.3068 0.961 0.859 1.08 0.0246 0.124 0.843 0.07436 1.02 0.804 1.31 -0.0709 0.127 0.576 0.2397 0.932 0.727 1.19 0.0753 0.123 0.54 0.2678 1.08 0.848 1.37 PRS_PLINK_0.001 FALSE 172.11 Melanomas of skin Both 569 5597 2 neoplasms darkcyan 5597, 569 1400, 142 1399, 142 1399, 134 1399, 151 -0.038 0.0571 0.505 0.2965 0.963 0.861 1.08 0.00375 0.124 0.976 0.0106 1 0.787 1.28 -0.0522 0.126 0.678 0.1689 0.949 0.742 1.21 0.0681 0.123 0.578 0.2378 1.07 0.842 1.36 PRS_PLINK_0.001 FALSE 172.2 Other non-epithelial cancer of skin Both 2332 22616 2 neoplasms darkcyan 22616, 2332 5654, 626 5654, 564 5654, 585 5654, 557 0.0136 0.0186 0.466 0.3312 1.01 0.977 1.05 -0.102 0.061 0.094 1.027 0.903 0.801 1.02 -0.0711 0.0605 0.24 0.6196 0.931 0.827 1.05 -0.116 0.0612 0.0583 1.234 0.891 0.79 1 PRS_PLINK_0.001 FALSE 172.3 Carcinoma in situ of skin Both 132 1352 2 neoplasms darkcyan 1352, 132 338, 31 338, 30 338, 28 338, 43 0.0441 0.0447 0.324 0.4899 1.05 0.957 1.14 -0.00234 0.263 0.993 0.003092 0.998 0.595 1.67 -0.159 0.269 0.554 0.2564 0.853 0.504 1.44 0.334 0.245 0.174 0.7603 1.4 0.863 2.26 PRS_PLINK_0.001 FALSE 173 Neoplasm of uncertain behavior of skin Both 40 404 2 neoplasms darkcyan 404, 40 101, 14 101, 13 101, 5 101, 8 -0.871 0.522 0.0953 1.021 0.418 0.15 1.16 0.00588 0.399 0.988 0.005141 1.01 0.46 2.2 -0.908 0.502 0.0703 1.153 0.403 0.151 1.08 -0.528 0.444 0.234 0.6303 0.59 0.247 1.41 PRS_PLINK_0.001 TRUE 174 Breast cancer Both 2499 26584 2 neoplasms darkcyan 26584, 2499 6645, 631 6646, 600 6646, 629 6646, 639 -0.0197 0.0224 0.378 0.422 0.98 0.938 1.02 -0.0516 0.0596 0.387 0.4126 0.95 0.845 1.07 -0.0034 0.0589 0.954 0.02044 0.997 0.888 1.12 0.011 0.0587 0.852 0.06976 1.01 0.901 1.13 PRS_PLINK_0.001 FALSE 174.1 Breast cancer [female] Female 2454 26111 2 neoplasms darkcyan 26111, 2454 6527, 616 6528, 592 6527, 615 6528, 631 -0.0178 0.0222 0.422 0.3744 0.982 0.941 1.03 -0.0414 0.0601 0.491 0.3088 0.959 0.853 1.08 -0.00177 0.0596 0.976 0.01041 0.998 0.888 1.12 0.022 0.0592 0.711 0.1482 1.02 0.91 1.15 PRS_PLINK_0.001 FALSE 174.11 Malignant neoplasm of female breast Female 2311 24551 2 neoplasms darkcyan 24551, 2311 6137, 584 6138, 561 6137, 572 6138, 594 -0.0168 0.023 0.465 0.3322 0.983 0.94 1.03 -0.0412 0.0618 0.505 0.2967 0.96 0.85 1.08 -0.0201 0.0615 0.743 0.1289 0.98 0.869 1.11 0.0147 0.061 0.809 0.092 1.01 0.901 1.14 PRS_PLINK_0.001 FALSE 174.3 Neoplasm of uncertain behavior of breast Both 25 256 2 neoplasms darkcyan 256, 25 64, 5 64, 7 64, 10 64, 3 -0.249 0.641 0.697 0.1565 0.779 0.222 2.74 0.623 0.558 0.265 0.5772 1.86 0.624 5.57 -0.577 0.695 0.407 0.3907 0.562 0.144 2.19 PRS_PLINK_0.001 TRUE 175 Acquired absence of breast Female 447 4981 2 neoplasms darkcyan 4981, 447 1246, 124 1245, 97 1245, 113 1245, 113 -0.000942 0.0431 0.983 0.007637 0.999 0.918 1.09 -0.239 0.141 0.0898 1.047 0.787 0.597 1.04 -0.0872 0.136 0.52 0.2838 0.916 0.703 1.2 -0.0926 0.135 0.494 0.3061 0.912 0.699 1.19 PRS_PLINK_0.001 FALSE 180 Cervical cancer and dysplasia Female 435 4987 2 neoplasms darkcyan 4987, 435 1246, 107 1247, 121 1246, 102 1247, 105 -0.0296 0.0684 0.665 0.1775 0.971 0.849 1.11 0.124 0.138 0.37 0.4316 1.13 0.864 1.48 -0.0509 0.143 0.723 0.1411 0.95 0.718 1.26 -0.0245 0.142 0.863 0.06386 0.976 0.738 1.29 PRS_PLINK_0.001 FALSE 180.1 Cervical cancer Female 51 587 2 neoplasms darkcyan 587, 51 147, 9 147, 15 146, 13 147, 14 0.0832 0.119 0.486 0.3136 1.09 0.86 1.37 0.459 0.414 0.268 0.5719 1.58 0.703 3.56 0.364 0.433 0.401 0.3967 1.44 0.616 3.36 0.43 0.42 0.305 0.515 1.54 0.675 3.5 PRS_PLINK_0.001 FALSE 180.3 Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia] Female 403 4725 2 neoplasms darkcyan 4725, 403 1181, 102 1181, 112 1181, 94 1181, 95 -0.0309 0.0669 0.644 0.191 0.97 0.85 1.11 0.0944 0.142 0.507 0.2952 1.1 0.832 1.45 -0.0871 0.148 0.556 0.2548 0.917 0.686 1.23 -0.0799 0.148 0.589 0.23 0.923 0.691 1.23 PRS_PLINK_0.001 FALSE 182 Malignant neoplasm of uterus Female 252 2658 2 neoplasms darkcyan 2658, 252 665, 61 664, 62 664, 65 665, 64 -0.0307 0.0618 0.62 0.2078 0.97 0.859 1.09 0.0212 0.187 0.909 0.04127 1.02 0.709 1.47 0.0512 0.185 0.782 0.1066 1.05 0.732 1.51 0.0286 0.186 0.878 0.05662 1.03 0.715 1.48 PRS_PLINK_0.001 FALSE 184 Cancer of other female genital organs Female 236 2776 2 neoplasms darkcyan 2776, 236 694, 55 694, 59 694, 69 694, 53 0.000267 0.0699 0.997 0.001325 1 0.872 1.15 0.0661 0.194 0.733 0.135 1.07 0.731 1.56 0.218 0.187 0.245 0.6113 1.24 0.862 1.79 -0.0531 0.198 0.789 0.1032 0.948 0.643 1.4 PRS_PLINK_0.001 FALSE 184.1 Malignant neoplasm of ovary and other uterine adnexa Female 168 1915 2 neoplasms darkcyan 1915, 168 479, 36 479, 48 478, 48 479, 36 0.00321 0.0683 0.963 0.01657 1 0.877 1.15 0.293 0.227 0.198 0.7034 1.34 0.858 2.09 0.277 0.227 0.223 0.6511 1.32 0.845 2.06 -0.0135 0.24 0.955 0.01995 0.987 0.616 1.58 PRS_PLINK_0.001 FALSE 184.11 Malignant neoplasm of ovary Female 163 1859 2 neoplasms darkcyan 1859, 163 465, 34 465, 47 464, 46 465, 36 0.00232 0.0686 0.973 0.01188 1 0.876 1.15 0.333 0.232 0.152 0.8188 1.39 0.885 2.2 0.294 0.233 0.207 0.6839 1.34 0.85 2.12 0.055 0.244 0.821 0.08543 1.06 0.655 1.7 PRS_PLINK_0.001 FALSE 184.2 Cancer of other female genital organs (excluding uterus and ovary) Female 45 592 2 neoplasms darkcyan 592, 45 148, 9 148, 10 148, 15 148, 11 0.115 0.497 0.816 0.08819 1.12 0.424 2.97 0.165 0.454 0.717 0.1446 1.18 0.484 2.87 0.472 0.417 0.257 0.5892 1.6 0.708 3.63 0.151 0.44 0.731 0.1362 1.16 0.491 2.76 PRS_PLINK_0.001 TRUE 185 Cancer of prostate Male 1281 12382 2 neoplasms darkcyan 12382, 1281 3096, 334 3095, 310 3095, 289 3096, 348 -0.0671 0.0514 0.192 0.7167 0.935 0.846 1.03 -0.072 0.0827 0.384 0.4153 0.931 0.791 1.09 -0.141 0.0841 0.0929 1.032 0.868 0.736 1.02 0.0472 0.0806 0.558 0.2533 1.05 0.895 1.23 PRS_PLINK_0.001 FALSE 187 Cancer of other male genital organs Male 96 940 2 neoplasms darkcyan 940, 96 235, 28 235, 22 235, 21 235, 25 0.0503 0.112 0.655 0.1838 1.05 0.843 1.31 -0.258 0.295 0.382 0.4181 0.773 0.434 1.38 -0.285 0.297 0.337 0.4727 0.752 0.42 1.35 -0.131 0.286 0.647 0.1893 0.877 0.501 1.54 PRS_PLINK_0.001 FALSE 187.1 Malignant neoplasm of unspecified male genital organ Male 14 159 2 neoplasms darkcyan 159, 14 40, 2 40, 5 39, 3 40, 4 0.325 1.02 0.75 0.1252 1.38 0.188 10.2 0.215 0.802 0.788 0.1033 1.24 0.258 5.97 0.405 0.835 0.628 0.2023 1.5 0.292 7.7 0.728 0.892 0.415 0.3823 2.07 0.36 11.9 PRS_PLINK_0.001 TRUE 187.2 Malignant neoplasm of testis Male 58 632 2 neoplasms darkcyan 632, 58 158, 18 158, 11 158, 15 158, 14 0.0322 0.101 0.75 0.1251 1.03 0.847 1.26 -0.465 0.382 0.223 0.6509 0.628 0.297 1.33 -0.129 0.356 0.717 0.1447 0.879 0.437 1.77 -0.167 0.365 0.646 0.1896 0.846 0.414 1.73 PRS_PLINK_0.001 FALSE 187.8 Neoplasm of uncertain behavior of male genital organs Male 29 207 2 neoplasms darkcyan 207, 29 52, 11 52, 6 51, 6 52, 6 -0.896 0.717 0.211 0.6749 0.408 0.1 1.66 -0.614 0.535 0.251 0.5998 0.541 0.19 1.54 -0.61 0.547 0.265 0.5772 0.543 0.186 1.59 -0.527 0.521 0.312 0.5053 0.591 0.213 1.64 PRS_PLINK_0.001 TRUE 189 Cancer of urinary organs (incl. kidney and bladder) Both 783 8605 2 neoplasms darkcyan 8605, 783 2152, 198 2151, 178 2151, 193 2151, 214 0.0584 0.0262 0.0257 1.591 1.06 1.01 1.12 -0.104 0.107 0.333 0.4774 0.901 0.73 1.11 -0.028 0.105 0.79 0.1022 0.972 0.791 1.2 0.0798 0.103 0.438 0.3586 1.08 0.885 1.33 PRS_PLINK_0.001 FALSE 189.1 Cancer of kidney and renal pelvis Both 210 2261 2 neoplasms darkcyan 2261, 210 566, 50 565, 51 565, 52 565, 57 0.0459 0.12 0.702 0.1539 1.05 0.828 1.32 0.0304 0.206 0.883 0.05405 1.03 0.688 1.54 0.0446 0.204 0.827 0.08248 1.05 0.701 1.56 0.139 0.201 0.49 0.3102 1.15 0.775 1.7 PRS_PLINK_0.001 FALSE 189.11 Malignant neoplasm of kidney, except pelvis Both 198 2184 2 neoplasms darkcyan 2184, 198 546, 43 546, 50 546, 50 546, 55 0.066 0.11 0.549 0.2602 1.07 0.861 1.33 0.166 0.214 0.44 0.3567 1.18 0.775 1.8 0.157 0.214 0.461 0.3363 1.17 0.77 1.78 0.255 0.21 0.226 0.6466 1.29 0.855 1.95 PRS_PLINK_0.001 FALSE 189.12 Malignant neoplasm of renal pelvis Both 16 125 2 neoplasms darkcyan 125, 16 32, 7 31, 3 31, 3 31, 3 -1.25 0.93 0.178 0.7493 0.286 0.0462 1.77 -0.773 0.789 0.327 0.4852 0.461 0.0982 2.17 -0.377 0.761 0.62 0.2074 0.686 0.154 3.05 -0.822 0.743 0.269 0.5707 0.44 0.102 1.89 PRS_PLINK_0.001 TRUE 189.2 Cancer of bladder Both 443 4896 2 neoplasms darkcyan 4896, 443 1224, 109 1224, 109 1224, 107 1224, 118 0.0271 0.0366 0.458 0.339 1.03 0.956 1.1 0.000767 0.141 0.996 0.001895 1 0.76 1.32 -0.0257 0.141 0.855 0.06783 0.975 0.739 1.29 0.0774 0.138 0.575 0.2402 1.08 0.824 1.42 PRS_PLINK_0.001 FALSE 189.21 Malignant neoplasm of bladder Both 402 4447 2 neoplasms darkcyan 4447, 402 1112, 100 1112, 101 1111, 98 1112, 103 0.0327 0.0379 0.387 0.4118 1.03 0.959 1.11 0.0087 0.146 0.953 0.02108 1.01 0.757 1.34 -0.0226 0.147 0.878 0.05639 0.978 0.732 1.3 0.031 0.146 0.832 0.08004 1.03 0.775 1.37 PRS_PLINK_0.001 FALSE 189.4 Malignant neoplasm of other urinary organs Both 32 313 2 neoplasms darkcyan 313, 32 79, 5 78, 11 78, 7 78, 9 0.222 0.467 0.635 0.197 1.25 0.5 3.12 0.63 0.52 0.226 0.6467 1.88 0.678 5.21 0.141 0.567 0.804 0.09497 1.15 0.379 3.5 0.483 0.552 0.382 0.418 1.62 0.549 4.78 PRS_PLINK_0.001 TRUE 190 Cancer of eye Both 24 368 2 neoplasms darkcyan 368, 24 92, 8 92, 5 92, 6 92, 5 -0.319 0.683 0.641 0.1932 0.727 0.19 2.78 -0.452 0.541 0.403 0.3948 0.636 0.22 1.84 -0.259 0.52 0.618 0.2088 0.772 0.279 2.14 -0.538 0.544 0.323 0.4915 0.584 0.201 1.7 PRS_PLINK_0.001 TRUE 191 Manlignant and unknown neoplasms of brain and nervous system Both 112 1459 2 neoplasms darkcyan 1459, 112 365, 33 365, 35 364, 23 365, 21 0.072 0.0657 0.273 0.5641 1.07 0.945 1.22 0.0599 0.25 0.81 0.09136 1.06 0.651 1.73 -0.336 0.275 0.222 0.6533 0.715 0.417 1.23 -0.444 0.282 0.115 0.9375 0.642 0.369 1.11 PRS_PLINK_0.001 FALSE 191.1 Cancer of brain and nervous system Both 86 1214 2 neoplasms darkcyan 1214, 86 304, 22 303, 29 303, 16 304, 19 0.122 0.0741 0.0983 1.008 1.13 0.978 1.31 0.272 0.287 0.343 0.4645 1.31 0.748 2.3 -0.278 0.326 0.394 0.4048 0.757 0.4 1.43 -0.118 0.313 0.706 0.1509 0.889 0.481 1.64 PRS_PLINK_0.001 FALSE 191.11 Cancer of brain Both 79 1117 2 neoplasms darkcyan 1117, 79 280, 23 279, 27 279, 15 279, 14 0.118 0.0748 0.116 0.9353 1.12 0.971 1.3 0.163 0.29 0.573 0.2416 1.18 0.667 2.08 -0.379 0.332 0.253 0.5967 0.684 0.357 1.31 -0.462 0.335 0.167 0.7765 0.63 0.327 1.21 PRS_PLINK_0.001 FALSE 193 Thyroid cancer Both 78 750 2 neoplasms darkcyan 750, 78 188, 24 187, 19 187, 20 188, 15 0.00508 0.0736 0.945 0.0246 1.01 0.87 1.16 -0.207 0.316 0.513 0.2902 0.813 0.438 1.51 -0.137 0.317 0.664 0.1777 0.872 0.469 1.62 -0.434 0.334 0.194 0.7115 0.648 0.336 1.25 PRS_PLINK_0.001 FALSE 194 Cancer of other endocrine glands Both 22 191 2 neoplasms darkcyan 191, 22 48, 6 48, 6 47, 6 48, 4 -0.21 0.593 0.723 0.1411 0.81 0.254 2.59 0.355 0.65 0.585 0.2329 1.43 0.399 5.09 0.193 0.665 0.772 0.1125 1.21 0.329 4.47 PRS_PLINK_0.001 TRUE 195 Cancer, suspected or other Both 3154 34995 2 neoplasms darkcyan 34995, 3154 8748, 791 8749, 775 8748, 786 8749, 802 0.0139 0.0158 0.38 0.4199 1.01 0.983 1.05 -0.0213 0.0527 0.686 0.1638 0.979 0.883 1.09 -0.00822 0.0526 0.876 0.05767 0.992 0.895 1.1 0.0128 0.0523 0.806 0.0936 1.01 0.914 1.12 PRS_PLINK_0.001 FALSE 195.1 Malignant neoplasm, other Both 3024 33644 2 neoplasms darkcyan 33644, 3024 8410, 753 8411, 746 8411, 754 8411, 771 0.019 0.0159 0.233 0.6318 1.02 0.988 1.05 -0.0103 0.0539 0.849 0.0712 0.99 0.891 1.1 -0.00128 0.0537 0.981 0.008334 0.999 0.899 1.11 0.0223 0.0535 0.676 0.1698 1.02 0.921 1.14 PRS_PLINK_0.001 FALSE 197 Chemotherapy Both 3859 45813 2 neoplasms darkcyan 45813, 3859 11453, 939 11453, 956 11453, 996 11453, 968 -0.0144 0.0181 0.428 0.3685 0.986 0.951 1.02 0.0169 0.0478 0.724 0.1405 1.02 0.926 1.12 0.0574 0.0473 0.225 0.6474 1.06 0.965 1.16 0.0302 0.0476 0.526 0.2789 1.03 0.939 1.13 PRS_PLINK_0.001 FALSE 198 Secondary malignant neoplasm Both 1598 20095 2 neoplasms darkcyan 20095, 1598 5024, 381 5024, 401 5023, 402 5024, 414 -0.0158 0.0278 0.569 0.245 0.984 0.932 1.04 0.0492 0.0742 0.507 0.2953 1.05 0.908 1.21 0.0525 0.0741 0.479 0.3195 1.05 0.911 1.22 0.08 0.0736 0.277 0.5574 1.08 0.938 1.25 PRS_PLINK_0.001 FALSE 198.1 Secondary malignancy of lymph nodes Both 928 11430 2 neoplasms darkcyan 11430, 928 2858, 225 2857, 212 2857, 251 2858, 240 -0.00779 0.0345 0.821 0.08551 0.992 0.927 1.06 -0.063 0.0991 0.525 0.2799 0.939 0.773 1.14 0.108 0.0953 0.257 0.5899 1.11 0.924 1.34 0.0603 0.0963 0.531 0.2748 1.06 0.88 1.28 PRS_PLINK_0.001 FALSE 198.2 Secondary malignancy of respiratory organs Both 341 4686 2 neoplasms darkcyan 4686, 341 1172, 77 1171, 78 1171, 94 1172, 92 -0.0217 0.0619 0.727 0.1387 0.979 0.867 1.1 0.00712 0.164 0.965 0.01529 1.01 0.73 1.39 0.208 0.158 0.188 0.7256 1.23 0.903 1.68 0.179 0.159 0.258 0.5879 1.2 0.877 1.63 PRS_PLINK_0.001 FALSE 198.3 Secondary malignant neoplasm of digestive systems Both 235 3150 2 neoplasms darkcyan 3150, 235 788, 53 787, 60 787, 65 788, 57 -0.0156 0.0652 0.811 0.09085 0.985 0.866 1.12 0.138 0.193 0.475 0.3231 1.15 0.786 1.68 0.232 0.19 0.223 0.6524 1.26 0.869 1.83 0.0686 0.195 0.725 0.1395 1.07 0.73 1.57 PRS_PLINK_0.001 FALSE 198.4 Secondary malignant neoplasm of liver Both 393 5579 2 neoplasms darkcyan 5579, 393 1395, 83 1395, 96 1394, 97 1395, 117 0.0333 0.0363 0.359 0.4445 1.03 0.963 1.11 0.148 0.153 0.335 0.475 1.16 0.858 1.57 0.181 0.153 0.237 0.6255 1.2 0.888 1.62 0.345 0.148 0.0194 1.712 1.41 1.06 1.89 PRS_PLINK_0.001 FALSE 198.5 Secondary malignancy of brain/spine Both 122 1813 2 neoplasms darkcyan 1813, 122 454, 21 453, 53 453, 22 453, 26 -0.343 0.3 0.253 0.5973 0.709 0.394 1.28 0.917 0.261 0.00045 3.347 2.5 1.5 4.18 -0.00889 0.303 0.977 0.01027 0.991 0.547 1.8 0.205 0.292 0.482 0.3166 1.23 0.693 2.18 PRS_PLINK_0.001 FALSE 198.6 Secondary malignancy of bone Both 328 4600 2 neoplasms darkcyan 4600, 328 1150, 75 1150, 81 1150, 85 1150, 87 -0.0104 0.0622 0.867 0.06198 0.99 0.876 1.12 0.0785 0.164 0.633 0.1989 1.08 0.784 1.49 0.118 0.162 0.468 0.3293 1.13 0.818 1.55 0.148 0.162 0.361 0.443 1.16 0.844 1.59 PRS_PLINK_0.001 FALSE 198.7 Secondary malignant neoplasm of skin Both 32 399 2 neoplasms darkcyan 399, 32 100, 7 100, 7 99, 8 100, 10 0.0566 0.119 0.635 0.1974 1.06 0.838 1.34 -0.247 0.534 0.643 0.1919 0.781 0.274 2.22 0.194 0.511 0.704 0.1522 1.21 0.446 3.3 0.252 0.487 0.605 0.2184 1.29 0.496 3.34 PRS_PLINK_0.001 TRUE 199 Neoplasm of uncertain behavior Both 268 3054 2 neoplasms darkcyan 3054, 268 764, 70 763, 63 763, 61 764, 74 -0.0157 0.079 0.842 0.07462 0.984 0.843 1.15 -0.103 0.179 0.567 0.2462 0.903 0.635 1.28 -0.136 0.181 0.453 0.3443 0.873 0.613 1.24 0.0477 0.173 0.783 0.1061 1.05 0.747 1.47 PRS_PLINK_0.001 FALSE 199.4 Neurofibromatosis Both 19 202 2 neoplasms darkcyan 202, 19 51, 7 50, 3 50, 6 51, 3 -0.613 0.779 0.432 0.365 0.542 0.118 2.49 -0.787 0.677 0.244 0.6118 0.455 0.121 1.71 -0.116 0.56 0.835 0.07809 0.89 0.297 2.67 -1.58 0.828 0.0563 1.25 0.206 0.0406 1.04 PRS_PLINK_0.001 TRUE 200 Myeloproliferative disease Both 176 2076 2 neoplasms darkcyan 2076, 176 519, 34 519, 55 519, 36 519, 51 0.0584 0.0481 0.225 0.6482 1.06 0.965 1.17 0.423 0.225 0.0595 1.226 1.53 0.983 2.37 0.0643 0.244 0.792 0.1012 1.07 0.661 1.72 0.372 0.226 0.101 0.9974 1.45 0.931 2.26 PRS_PLINK_0.001 FALSE 200.1 Polycythemia vera Both 55 801 2 neoplasms darkcyan 801, 55 201, 8 200, 21 200, 8 200, 18 0.747 0.474 0.115 0.9396 2.11 0.834 5.34 0.992 0.412 0.016 1.795 2.7 1.2 6.05 -0.11 0.479 0.818 0.08742 0.895 0.35 2.29 0.761 0.41 0.0637 1.196 2.14 0.958 4.78 PRS_PLINK_0.001 FALSE 201 Hodgkin's disease Both 50 583 2 neoplasms darkcyan 583, 50 146, 12 146, 17 145, 9 146, 12 0.0556 0.119 0.641 0.1929 1.06 0.837 1.34 0.283 0.381 0.457 0.3399 1.33 0.629 2.8 -0.32 0.431 0.458 0.3392 0.726 0.312 1.69 -0.00626 0.408 0.988 0.005354 0.994 0.447 2.21 PRS_PLINK_0.001 TRUE 202 Cancer of other lymphoid, histiocytic tissue Both 422 4807 2 neoplasms darkcyan 4807, 422 1202, 100 1202, 116 1201, 111 1202, 95 -0.0347 0.068 0.61 0.2149 0.966 0.845 1.1 0.148 0.142 0.297 0.5275 1.16 0.878 1.53 0.101 0.143 0.477 0.3211 1.11 0.837 1.46 -0.0528 0.148 0.721 0.142 0.949 0.71 1.27 PRS_PLINK_0.001 FALSE 202.2 Non-Hodgkins lymphoma Both 346 3762 2 neoplasms darkcyan 3762, 346 941, 83 940, 92 940, 96 941, 75 -0.0278 0.0686 0.686 0.1638 0.973 0.85 1.11 0.105 0.157 0.506 0.2961 1.11 0.816 1.51 0.143 0.156 0.359 0.4446 1.15 0.85 1.56 -0.107 0.164 0.514 0.2889 0.898 0.651 1.24 PRS_PLINK_0.001 FALSE 202.21 Nodular lymphoma Both 61 782 2 neoplasms darkcyan 782, 61 196, 14 195, 16 195, 19 196, 12 0.0316 0.0916 0.73 0.1366 1.03 0.863 1.23 0.095 0.364 0.794 0.1002 1.1 0.539 2.24 0.325 0.357 0.364 0.4391 1.38 0.687 2.79 -0.0945 0.386 0.807 0.09324 0.91 0.427 1.94 PRS_PLINK_0.001 FALSE 202.24 Large cell lymphoma Both 109 1201 2 neoplasms darkcyan 1201, 109 301, 18 300, 35 300, 36 300, 20 0.0465 0.0905 0.607 0.2166 1.05 0.877 1.25 0.697 0.295 0.0181 1.742 2.01 1.13 3.58 0.63 0.295 0.0324 1.489 1.88 1.05 3.35 0.153 0.326 0.637 0.1956 1.17 0.616 2.21 PRS_PLINK_0.001 FALSE 204 Leukemia Both 303 3496 2 neoplasms darkcyan 3496, 303 874, 63 874, 70 874, 88 874, 82 0.0121 0.0625 0.846 0.07269 1.01 0.896 1.14 0.105 0.178 0.556 0.255 1.11 0.784 1.57 0.333 0.17 0.0504 1.297 1.4 0.999 1.95 0.259 0.172 0.133 0.8767 1.3 0.924 1.82 PRS_PLINK_0.001 FALSE 204.1 Lymphoid leukemia Both 120 1193 2 neoplasms darkcyan 1193, 120 299, 19 298, 24 298, 44 298, 33 0.0928 0.102 0.365 0.4377 1.1 0.898 1.34 0.231 0.306 0.451 0.3462 1.26 0.691 2.3 0.85 0.281 0.0025 2.603 2.34 1.35 4.06 0.557 0.292 0.0563 1.25 1.75 0.985 3.09 PRS_PLINK_0.001 FALSE 204.11 Lymphoid leukemia, acute Both 7 120 2 neoplasms darkcyan 120, 7 30, 2 30, 1 30, 1 30, 3 0.623 0.598 0.297 0.5274 1.87 0.578 6.02 -0.0865 0.962 0.928 0.03229 0.917 0.139 6.05 0.166 0.998 0.868 0.06153 1.18 0.167 8.35 0.609 0.809 0.452 0.345 1.84 0.376 8.99 PRS_PLINK_0.001 TRUE 204.12 Lymphoid leukemia, chronic Both 105 1035 2 neoplasms darkcyan 1035, 105 259, 14 259, 23 258, 41 259, 27 0.0824 0.105 0.433 0.3639 1.09 0.884 1.33 0.473 0.335 0.158 0.8025 1.61 0.833 3.1 1.1 0.315 0.000483 3.316 3.01 1.62 5.58 0.632 0.329 0.0543 1.265 1.88 0.988 3.58 PRS_PLINK_0.001 FALSE 204.2 Myeloid leukemia Both 72 998 2 neoplasms darkcyan 998, 72 250, 17 249, 12 249, 21 250, 22 0.0902 0.113 0.425 0.3712 1.09 0.877 1.37 -0.307 0.368 0.404 0.3933 0.736 0.358 1.51 0.207 0.327 0.526 0.2787 1.23 0.648 2.34 0.225 0.326 0.49 0.3099 1.25 0.661 2.37 PRS_PLINK_0.001 FALSE 204.21 Myeloid leukemia, acute Both 49 708 2 neoplasms darkcyan 708, 49 177, 10 177, 10 177, 13 177, 16 0.117 0.111 0.292 0.534 1.12 0.904 1.4 0.0332 0.431 0.939 0.02751 1.03 0.444 2.41 0.442 0.419 0.291 0.5359 1.56 0.685 3.54 0.472 0.403 0.242 0.6169 1.6 0.727 3.54 PRS_PLINK_0.001 TRUE 204.22 Myeloid leukemia, chronic Both 25 311 2 neoplasms darkcyan 311, 25 78, 7 78, 4 77, 8 78, 6 -0.386 0.72 0.592 0.2277 0.68 0.166 2.79 -0.593 0.587 0.312 0.5058 0.553 0.175 1.74 0.0981 0.543 0.857 0.06719 1.1 0.38 3.2 -0.0224 0.552 0.968 0.01428 0.978 0.332 2.88 PRS_PLINK_0.001 TRUE 204.4 Multiple myeloma Both 94 1151 2 neoplasms darkcyan 1151, 94 288, 20 288, 27 287, 21 288, 26 0.0228 0.0953 0.811 0.09082 1.02 0.849 1.23 0.3 0.297 0.312 0.5056 1.35 0.755 2.41 0.0209 0.314 0.947 0.02364 1.02 0.551 1.89 0.242 0.301 0.421 0.3755 1.27 0.706 2.3 PRS_PLINK_0.001 FALSE 208 Benign neoplasm of colon Both 3779 40480 2 neoplasms darkcyan 40480, 3779 10119, 928 10120, 918 10120, 921 10120, 1012 0.0202 0.0136 0.137 0.8637 1.02 0.994 1.05 -0.0112 0.0486 0.818 0.08742 0.989 0.899 1.09 -0.00958 0.0486 0.844 0.07388 0.99 0.901 1.09 0.0849 0.0476 0.0741 1.13 1.09 0.992 1.2 PRS_PLINK_0.001 FALSE 210 Benign neoplasm of lip, oral cavity, and pharynx Both 201 2085 2 neoplasms darkcyan 2085, 201 522, 39 521, 56 521, 47 521, 59 0.0908 0.0528 0.085 1.07 1.1 0.988 1.21 0.345 0.215 0.108 0.9666 1.41 0.927 2.15 0.191 0.221 0.388 0.4108 1.21 0.784 1.87 0.424 0.213 0.0465 1.332 1.53 1.01 2.32 PRS_PLINK_0.001 FALSE 211 Benign neoplasm of other parts of digestive system Both 1042 11027 2 neoplasms darkcyan 11027, 1042 2757, 259 2757, 262 2756, 272 2757, 249 -0.0782 0.0553 0.157 0.8038 0.925 0.83 1.03 0.00948 0.0915 0.917 0.03742 1.01 0.844 1.21 0.0447 0.0907 0.622 0.2063 1.05 0.875 1.25 -0.0425 0.0926 0.646 0.1896 0.958 0.799 1.15 PRS_PLINK_0.001 FALSE 212 Benign neoplasm of respiratory and intrathoracic organs Both 50 724 2 neoplasms darkcyan 724, 50 181, 12 181, 10 181, 14 181, 14 0.079 0.118 0.504 0.2976 1.08 0.858 1.36 -0.16 0.419 0.702 0.1538 0.852 0.375 1.94 0.122 0.387 0.752 0.1239 1.13 0.529 2.41 0.197 0.393 0.617 0.2096 1.22 0.563 2.63 PRS_PLINK_0.001 TRUE 213 Benign neoplasm of bone and articular cartilage Both 55 637 2 neoplasms darkcyan 637, 55 160, 14 159, 15 159, 14 159, 12 -0.592 0.438 0.176 0.7533 0.553 0.235 1.31 0.0137 0.374 0.971 0.01289 1.01 0.487 2.11 0.0248 0.378 0.948 0.02338 1.03 0.489 2.15 -0.255 0.396 0.52 0.2836 0.775 0.357 1.69 PRS_PLINK_0.001 FALSE 214 Lipoma Both 1214 13427 2 neoplasms darkcyan 13427, 1214 3357, 306 3357, 298 3356, 295 3357, 315 0.0266 0.0233 0.255 0.5939 1.03 0.981 1.07 -0.0263 0.0848 0.756 0.1212 0.974 0.825 1.15 -0.0391 0.085 0.646 0.1898 0.962 0.814 1.14 0.0273 0.0837 0.745 0.1281 1.03 0.872 1.21 PRS_PLINK_0.001 FALSE 214.1 Lipoma of skin and subcutaneous tissue Both 882 10018 2 neoplasms darkcyan 10018, 882 2505, 225 2504, 222 2504, 213 2505, 222 0.029 0.0262 0.268 0.5722 1.03 0.978 1.08 -0.00888 0.0985 0.928 0.03237 0.991 0.817 1.2 -0.0541 0.0994 0.586 0.2318 0.947 0.78 1.15 -0.016 0.0985 0.871 0.06001 0.984 0.811 1.19 PRS_PLINK_0.001 FALSE 215 Other benign neoplasm of connective and other soft tissue Both 212 2408 2 neoplasms darkcyan 2408, 212 602, 51 602, 59 602, 44 602, 58 0.0971 0.0387 0.0121 1.917 1.1 1.02 1.19 0.15 0.197 0.448 0.3487 1.16 0.789 1.71 -0.174 0.211 0.409 0.3884 0.84 0.556 1.27 0.136 0.198 0.493 0.3076 1.15 0.777 1.69 PRS_PLINK_0.001 FALSE 216 Benign neoplasm of skin Both 1572 16559 2 neoplasms darkcyan 16559, 1572 4140, 395 4140, 363 4139, 382 4140, 432 0.014 0.0218 0.52 0.2837 1.01 0.972 1.06 -0.0844 0.0758 0.266 0.5758 0.919 0.792 1.07 -0.0362 0.075 0.629 0.2015 0.964 0.833 1.12 0.0874 0.0729 0.231 0.637 1.09 0.946 1.26 PRS_PLINK_0.001 FALSE 217 Vascular hamartomas and non-neoplastic nevi Both 103 1249 2 neoplasms darkcyan 1249, 103 313, 26 312, 28 312, 28 312, 21 0.0964 0.0706 0.172 0.7638 1.1 0.959 1.26 0.0976 0.28 0.727 0.1383 1.1 0.637 1.91 0.0183 0.28 0.948 0.02321 1.02 0.588 1.76 -0.183 0.299 0.541 0.2669 0.833 0.464 1.5 PRS_PLINK_0.001 FALSE 217.1 Nevus, non-neoplastic Both 93 1162 2 neoplasms darkcyan 1162, 93 291, 22 290, 24 290, 27 291, 20 0.103 0.0699 0.141 0.8506 1.11 0.966 1.27 0.111 0.3 0.711 0.148 1.12 0.621 2.01 0.158 0.293 0.589 0.2299 1.17 0.66 2.08 -0.0923 0.311 0.767 0.1152 0.912 0.495 1.68 PRS_PLINK_0.001 FALSE 218 Benign neoplasm of uterus Female 2123 22361 2 neoplasms darkcyan 22361, 2123 5591, 506 5590, 530 5590, 561 5590, 526 -0.00574 0.0209 0.783 0.1062 0.994 0.954 1.04 0.0469 0.0649 0.47 0.3283 1.05 0.923 1.19 0.103 0.0641 0.108 0.967 1.11 0.978 1.26 0.0395 0.065 0.543 0.2651 1.04 0.916 1.18 PRS_PLINK_0.001 FALSE 218.1 Uterine leiomyoma Female 2124 22609 2 neoplasms darkcyan 22609, 2124 5653, 512 5652, 530 5652, 557 5652, 525 -0.0125 0.0231 0.589 0.2296 0.988 0.944 1.03 0.0363 0.0647 0.575 0.2403 1.04 0.913 1.18 0.0844 0.064 0.187 0.7275 1.09 0.96 1.23 0.0265 0.0648 0.683 0.1658 1.03 0.904 1.17 PRS_PLINK_0.001 FALSE 218.2 Other benign neoplasm of uterus Female 65 811 2 neoplasms darkcyan 811, 65 203, 15 203, 18 202, 17 203, 15 0.0532 0.0501 0.288 0.5399 1.05 0.956 1.16 0.124 0.353 0.726 0.1388 1.13 0.566 2.26 0.144 0.358 0.686 0.1634 1.16 0.573 2.33 0.0189 0.364 0.959 0.01834 1.02 0.499 2.08 PRS_PLINK_0.001 FALSE 220 Benign neoplasm of ovary Female 294 3104 2 neoplasms darkcyan 3104, 294 776, 65 776, 68 776, 78 776, 83 0.0596 0.0492 0.225 0.6477 1.06 0.964 1.17 0.08 0.18 0.657 0.1822 1.08 0.761 1.54 0.182 0.174 0.296 0.5294 1.2 0.853 1.69 0.247 0.172 0.151 0.8198 1.28 0.913 1.8 PRS_PLINK_0.001 FALSE 221 Benign neoplasm of other female genital organs Female 41 459 2 neoplasms darkcyan 459, 41 115, 11 115, 7 114, 11 115, 12 0.0406 0.0678 0.549 0.26 1.04 0.912 1.19 -0.437 0.477 0.359 0.4452 0.646 0.254 1.64 -0.0186 0.431 0.966 0.01517 0.982 0.421 2.29 0.00565 0.42 0.989 0.004692 1.01 0.442 2.29 PRS_PLINK_0.001 TRUE 222 Benign neoplasm of male genital organs Male 34 359 2 neoplasms darkcyan 359, 34 90, 7 90, 8 89, 14 90, 5 0.0604 0.116 0.602 0.2201 1.06 0.846 1.33 0.163 0.512 0.75 0.1247 1.18 0.431 3.21 0.658 0.461 0.153 0.8154 1.93 0.783 4.76 -0.268 0.548 0.624 0.2049 0.765 0.261 2.24 PRS_PLINK_0.001 TRUE 223 Benign neoplasm of kidney and other urinary organs Both 29 376 2 neoplasms darkcyan 376, 29 94, 7 94, 8 94, 10 94, 4 -0.695 0.642 0.279 0.5538 0.499 0.142 1.76 0.237 0.504 0.639 0.1947 1.27 0.472 3.4 0.457 0.496 0.357 0.4474 1.58 0.598 4.17 -0.673 0.585 0.251 0.6011 0.51 0.162 1.61 PRS_PLINK_0.001 TRUE 224 Benign neoplasm of eye Both 24 271 2 neoplasms darkcyan 271, 24 68, 6 68, 7 67, 5 68, 6 -0.18 0.719 0.803 0.09549 0.835 0.204 3.42 0.151 0.543 0.781 0.1075 1.16 0.401 3.37 -0.107 0.595 0.857 0.06681 0.899 0.28 2.88 -0.0934 0.556 0.867 0.0622 0.911 0.307 2.71 PRS_PLINK_0.001 TRUE 224.1 Benign neoplasm of eye, uveal Both 12 144 2 neoplasms darkcyan 144, 12 36, 3 36, 4 36, 3 36, 2 -0.538 1.01 0.593 0.2271 0.584 0.0812 4.2 0.639 0.828 0.44 0.3561 1.89 0.374 9.59 0.307 0.826 0.71 0.1488 1.36 0.269 6.87 -0.318 0.97 0.743 0.1288 0.728 0.109 4.88 PRS_PLINK_0.001 TRUE 225 Benign neoplasm of brain and other parts of nervous system Both 174 1695 2 neoplasms darkcyan 1695, 174 424, 47 424, 42 423, 42 424, 43 -0.0146 0.0837 0.862 0.06467 0.986 0.836 1.16 -0.112 0.221 0.611 0.2139 0.894 0.58 1.38 -0.0812 0.221 0.714 0.1465 0.922 0.598 1.42 -0.0878 0.218 0.688 0.1626 0.916 0.597 1.41 PRS_PLINK_0.001 FALSE 225.1 Benign neoplasm of brain, cranial nerves, meninges Both 162 1611 2 neoplasms darkcyan 1611, 162 403, 44 403, 39 402, 41 403, 38 -0.0168 0.086 0.845 0.07322 0.983 0.831 1.16 -0.111 0.228 0.625 0.2039 0.895 0.572 1.4 -0.0247 0.227 0.913 0.0393 0.976 0.625 1.52 -0.141 0.229 0.537 0.2702 0.868 0.554 1.36 PRS_PLINK_0.001 FALSE 225.2 Benign neoplasm of spinal cord, meninges Both 14 114 2 neoplasms darkcyan 114, 14 29, 5 28, 2 28, 4 29, 3 0.366 0.962 0.704 0.1525 1.44 0.219 9.5 -0.797 0.893 0.372 0.4289 0.451 0.0783 2.6 0.77 0.838 0.358 0.4462 2.16 0.418 11.2 -0.551 0.754 0.465 0.3326 0.577 0.132 2.53 PRS_PLINK_0.001 TRUE 226 Benign neoplasm of thyroid glands Both 54 592 2 neoplasms darkcyan 592, 54 148, 14 148, 10 148, 13 148, 17 0.0547 0.0941 0.561 0.2513 1.06 0.878 1.27 -0.245 0.415 0.555 0.2561 0.783 0.347 1.76 -0.0745 0.385 0.847 0.0723 0.928 0.437 1.97 0.237 0.373 0.525 0.2799 1.27 0.61 2.63 PRS_PLINK_0.001 FALSE 227 Benign neoplasm of other endocrine glands and related structures Both 168 1856 2 neoplasms darkcyan 1856, 168 464, 37 464, 45 464, 42 464, 44 0.0418 0.0484 0.388 0.4114 1.04 0.948 1.15 0.207 0.23 0.368 0.4338 1.23 0.783 1.93 0.119 0.232 0.609 0.2157 1.13 0.715 1.77 0.141 0.23 0.54 0.2678 1.15 0.734 1.81 PRS_PLINK_0.001 FALSE 227.1 Benign neoplasm of adrenal gland Both 35 408 2 neoplasms darkcyan 408, 35 102, 7 102, 7 102, 12 102, 9 0.543 0.561 0.333 0.4775 1.72 0.573 5.16 -0.165 0.538 0.759 0.12 0.848 0.296 2.43 0.467 0.467 0.317 0.4986 1.6 0.639 3.98 0.21 0.486 0.665 0.1773 1.23 0.476 3.2 PRS_PLINK_0.001 TRUE 227.2 Benign neoplasm of parathyroid gland Both 75 777 2 neoplasms darkcyan 777, 75 195, 16 194, 26 194, 15 194, 18 0.0288 0.0907 0.751 0.1244 1.03 0.862 1.23 0.535 0.329 0.104 0.9837 1.71 0.896 3.25 -0.0662 0.358 0.853 0.06897 0.936 0.464 1.89 0.166 0.348 0.633 0.1989 1.18 0.597 2.33 PRS_PLINK_0.001 FALSE 227.3 Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch) Both 60 660 2 neoplasms darkcyan 660, 60 165, 13 165, 16 165, 17 165, 14 0.0534 0.0548 0.329 0.4824 1.05 0.948 1.17 0.129 0.381 0.735 0.1339 1.14 0.54 2.4 0.176 0.372 0.637 0.1956 1.19 0.574 2.47 -0.00757 0.387 0.984 0.006837 0.992 0.465 2.12 PRS_PLINK_0.001 FALSE 228 Hemangioma and lymphangioma, any site Both 309 3397 2 neoplasms darkcyan 3397, 309 850, 87 849, 81 849, 66 849, 75 0.0505 0.0575 0.379 0.4212 1.05 0.94 1.18 -0.0476 0.161 0.767 0.115 0.953 0.695 1.31 -0.262 0.169 0.121 0.9175 0.77 0.553 1.07 -0.129 0.164 0.432 0.3648 0.879 0.637 1.21 PRS_PLINK_0.001 FALSE 229 Benign neoplasm of unspecified sites Both 472 5159 2 neoplasms darkcyan 5159, 472 1289, 109 1290, 108 1289, 123 1290, 132 0.0464 0.0288 0.107 0.9695 1.05 0.99 1.11 -0.0118 0.141 0.933 0.03009 0.988 0.75 1.3 0.127 0.137 0.354 0.4511 1.14 0.868 1.48 0.186 0.135 0.167 0.7765 1.2 0.925 1.57 PRS_PLINK_0.001 FALSE 240 Simple and unspecified goiter Both 119 1289 3 endocrine/metabolic brown 1289, 119 323, 28 322, 29 322, 26 322, 36 0.0146 0.0609 0.81 0.09126 1.01 0.901 1.14 0.0349 0.271 0.897 0.047 1.04 0.609 1.76 -0.0728 0.277 0.792 0.1012 0.93 0.541 1.6 0.208 0.26 0.425 0.3718 1.23 0.739 2.05 PRS_PLINK_0.001 FALSE 241 Nontoxic nodular goiter Both 229 2379 3 endocrine/metabolic brown 2379, 229 595, 46 595, 65 594, 61 595, 57 0.0162 0.064 0.8 0.09706 1.02 0.897 1.15 0.351 0.199 0.0786 1.104 1.42 0.961 2.1 0.295 0.201 0.143 0.8449 1.34 0.905 1.99 0.216 0.204 0.29 0.5379 1.24 0.832 1.85 PRS_PLINK_0.001 FALSE 241.1 Nontoxic uninodular goiter Both 98 1054 3 endocrine/metabolic brown 1054, 98 264, 19 263, 24 263, 26 264, 29 0.0545 0.0775 0.482 0.3171 1.06 0.907 1.23 0.255 0.31 0.412 0.3853 1.29 0.702 2.37 0.317 0.308 0.304 0.5172 1.37 0.75 2.51 0.485 0.302 0.109 0.9634 1.62 0.898 2.94 PRS_PLINK_0.001 FALSE 241.2 Nontoxic multinodular goiter Both 138 1431 3 endocrine/metabolic brown 1431, 138 358, 31 358, 40 357, 37 358, 30 0.0458 0.0901 0.611 0.214 1.05 0.877 1.25 0.215 0.248 0.386 0.4132 1.24 0.763 2.01 0.177 0.251 0.482 0.3169 1.19 0.729 1.95 -0.0245 0.262 0.925 0.03364 0.976 0.584 1.63 PRS_PLINK_0.001 FALSE 242 Thyrotoxicosis with or without goiter Both 335 3881 3 endocrine/metabolic brown 3881, 335 971, 74 970, 89 970, 82 970, 90 -0.0158 0.0694 0.82 0.08639 0.984 0.859 1.13 0.178 0.163 0.275 0.5613 1.19 0.868 1.64 0.0908 0.165 0.583 0.2345 1.1 0.792 1.51 0.196 0.162 0.226 0.645 1.22 0.885 1.67 PRS_PLINK_0.001 FALSE 242.1 Graves' disease Both 87 983 3 endocrine/metabolic brown 983, 87 246, 20 246, 25 245, 21 246, 21 -0.121 0.371 0.744 0.1285 0.886 0.428 1.83 0.161 0.307 0.6 0.2219 1.17 0.643 2.15 0.00405 0.318 0.99 0.004442 1 0.539 1.87 0.00469 0.317 0.988 0.005157 1 0.54 1.87 PRS_PLINK_0.001 FALSE 242.2 Toxic multinodular goiter Both 14 184 3 endocrine/metabolic brown 184, 14 46, 6 46, 3 46, 1 46, 4 -0.335 0.858 0.697 0.1571 0.716 0.133 3.84 -0.491 0.679 0.469 0.3285 0.612 0.162 2.31 -1.65 0.891 0.0632 1.199 0.191 0.0333 1.1 -0.514 0.677 0.448 0.3492 0.598 0.159 2.25 PRS_PLINK_0.001 TRUE 242.3 Exophthalmos Both 20 290 3 endocrine/metabolic brown 290, 20 73, 4 72, 6 72, 4 73, 6 -0.368 0.648 0.57 0.2444 0.692 0.194 2.46 0.0936 0.619 0.88 0.05565 1.1 0.327 3.69 0.0754 0.65 0.908 0.04207 1.08 0.302 3.86 0.246 0.612 0.687 0.1629 1.28 0.385 4.25 PRS_PLINK_0.001 TRUE 244 Hypothyroidism Both 2723 30327 3 endocrine/metabolic brown 30327, 2723 7582, 630 7582, 716 7581, 719 7582, 657 -0.017 0.0217 0.434 0.3629 0.983 0.942 1.03 0.131 0.057 0.0218 1.661 1.14 1.02 1.27 0.133 0.0569 0.0194 1.711 1.14 1.02 1.28 0.0409 0.058 0.481 0.3182 1.04 0.93 1.17 PRS_PLINK_0.001 FALSE 244.1 Secondary hypothyroidism Both 212 2318 3 endocrine/metabolic brown 2318, 212 580, 44 579, 67 579, 55 580, 46 -0.0313 0.0769 0.684 0.1651 0.969 0.834 1.13 0.412 0.2 0.0396 1.402 1.51 1.02 2.24 0.223 0.208 0.284 0.5466 1.25 0.831 1.88 0.0183 0.217 0.933 0.0302 1.02 0.665 1.56 PRS_PLINK_0.001 FALSE 244.2 Acquired hypothyroidism Both 21 207 3 endocrine/metabolic brown 207, 21 52, 6 52, 6 51, 2 52, 7 0.265 0.626 0.672 0.1727 1.3 0.382 4.44 0.0676 0.584 0.908 0.04196 1.07 0.341 3.36 -1.07 0.744 0.149 0.8256 0.342 0.0797 1.47 0.287 0.569 0.613 0.2122 1.33 0.437 4.06 PRS_PLINK_0.001 TRUE 244.4 Hypothyroidism NOS Both 2588 28955 3 endocrine/metabolic brown 28955, 2588 7239, 601 7239, 678 7238, 683 7239, 625 -0.0163 0.0218 0.455 0.3423 0.984 0.943 1.03 0.123 0.0584 0.0355 1.45 1.13 1.01 1.27 0.128 0.0583 0.0286 1.543 1.14 1.01 1.27 0.0376 0.0594 0.527 0.278 1.04 0.924 1.17 PRS_PLINK_0.001 FALSE 245 Thyroiditis Both 56 618 3 endocrine/metabolic brown 618, 56 155, 10 154, 16 154, 17 155, 13 0.102 0.0575 0.077 1.114 1.11 0.989 1.24 0.43 0.406 0.29 0.5369 1.54 0.693 3.41 0.495 0.397 0.212 0.6735 1.64 0.754 3.57 0.28 0.414 0.499 0.3016 1.32 0.587 2.98 PRS_PLINK_0.001 FALSE 245.2 Chronic thyroiditis Both 42 469 3 endocrine/metabolic brown 469, 42 118, 8 117, 11 117, 12 117, 11 0.0965 0.059 0.102 0.99 1.1 0.981 1.24 0.176 0.475 0.711 0.1482 1.19 0.47 3.02 0.334 0.446 0.453 0.3435 1.4 0.583 3.34 0.243 0.462 0.599 0.2224 1.28 0.515 3.16 PRS_PLINK_0.001 TRUE 245.21 Chronic lymphocytic thyroiditis Both 42 446 3 endocrine/metabolic brown 446, 42 112, 8 111, 10 111, 13 112, 11 0.109 0.0768 0.155 0.81 1.12 0.96 1.3 0.117 0.482 0.809 0.09205 1.12 0.437 2.89 0.421 0.442 0.341 0.4668 1.52 0.64 3.62 0.281 0.465 0.546 0.2631 1.32 0.532 3.29 PRS_PLINK_0.001 TRUE 246 Other disorders of thyroid Both 84 849 3 endocrine/metabolic brown 849, 84 213, 19 212, 17 212, 16 212, 32 0.107 0.103 0.3 0.5224 1.11 0.909 1.36 -0.114 0.335 0.734 0.1344 0.892 0.462 1.72 -0.17 0.339 0.617 0.2101 0.844 0.434 1.64 0.517 0.3 0.0847 1.072 1.68 0.932 3.02 PRS_PLINK_0.001 FALSE 250 Diabetes mellitus Both 3293 39670 3 endocrine/metabolic brown 39670, 3293 9918, 766 9917, 820 9917, 818 9918, 889 -0.00923 0.0182 0.613 0.2126 0.991 0.956 1.03 0.0683 0.0522 0.191 0.7196 1.07 0.967 1.19 0.0649 0.0522 0.214 0.6702 1.07 0.963 1.18 0.149 0.0513 0.00379 2.422 1.16 1.05 1.28 PRS_PLINK_0.001 FALSE 250.1 Type 1 diabetes Both 448 5965 3 endocrine/metabolic brown 5965, 448 1492, 99 1491, 111 1491, 102 1491, 136 0.025 0.0349 0.474 0.3238 1.03 0.958 1.1 0.118 0.142 0.404 0.3934 1.13 0.852 1.49 0.0317 0.145 0.827 0.08252 1.03 0.777 1.37 0.314 0.136 0.0216 1.666 1.37 1.05 1.79 PRS_PLINK_0.001 FALSE 250.11 Type 1 diabetes with ketoacidosis Both 33 552 3 endocrine/metabolic brown 552, 33 138, 8 138, 9 138, 4 138, 12 0.435 0.582 0.455 0.3421 1.54 0.494 4.83 0.257 0.466 0.581 0.2357 1.29 0.519 3.22 -0.55 0.551 0.318 0.497 0.577 0.196 1.7 0.482 0.449 0.283 0.5486 1.62 0.672 3.91 PRS_PLINK_0.001 TRUE 250.12 Type 1 diabetes with renal manifestations Both 6 173 3 endocrine/metabolic brown 173, 6 44, 1 43, 2 43, 2 43, 1 -0.0979 0.93 0.916 0.03805 0.907 0.147 5.61 0.0507 0.951 0.957 0.01888 1.05 0.163 6.78 -0.366 1.04 0.726 0.1393 0.693 0.0897 5.36 PRS_PLINK_0.001 TRUE 250.13 Type 1 diabetes with ophthalmic manifestations Both 69 1018 3 endocrine/metabolic brown 1018, 69 255, 11 254, 17 254, 19 255, 22 0.0726 0.0461 0.115 0.9395 1.08 0.982 1.18 0.376 0.381 0.323 0.4904 1.46 0.69 3.07 0.603 0.371 0.104 0.9843 1.83 0.884 3.78 0.692 0.366 0.0585 1.233 2 0.976 4.09 PRS_PLINK_0.001 FALSE 250.14 Type 1 diabetes with neurological manifestations Both 15 334 3 endocrine/metabolic brown 334, 15 84, 8 83, 1 83, 2 84, 4 -1.13 0.814 0.165 0.7818 0.323 0.0656 1.59 -1.71 0.806 0.0341 1.467 0.181 0.0374 0.88 -1.06 0.678 0.117 0.9332 0.345 0.0914 1.3 -0.784 0.582 0.178 0.7501 0.457 0.146 1.43 PRS_PLINK_0.001 TRUE 250.2 Type 2 diabetes Both 2942 36101 3 endocrine/metabolic brown 36101, 2942 9026, 686 9025, 731 9025, 732 9025, 793 -0.00016 0.0187 0.993 0.002959 1 0.964 1.04 0.0633 0.0552 0.251 0.6001 1.07 0.956 1.19 0.0641 0.0551 0.245 0.6113 1.07 0.957 1.19 0.145 0.0542 0.0076 2.119 1.16 1.04 1.29 PRS_PLINK_0.001 FALSE 250.21 Type 2 diabetes with ketoacidosis Both 14 234 3 endocrine/metabolic brown 234, 14 59, 7 58, 3 58, 1 59, 3 -0.768 0.895 0.391 0.4078 0.464 0.0804 2.68 -0.543 0.641 0.397 0.4013 0.581 0.166 2.04 -1.38 0.81 0.0884 1.053 0.252 0.0514 1.23 -0.445 0.633 0.483 0.3164 0.641 0.185 2.22 PRS_PLINK_0.001 TRUE 250.22 Type 2 diabetes with renal manifestations Both 15 412 3 endocrine/metabolic brown 412, 15 103, 5 103, 2 103, 4 103, 4 -1.47 0.7 0.0364 1.439 0.231 0.0585 0.911 -0.704 0.674 0.296 0.5281 0.495 0.132 1.85 -0.139 0.594 0.815 0.08884 0.87 0.272 2.79 -0.174 0.645 0.788 0.1036 0.841 0.237 2.98 PRS_PLINK_0.001 TRUE 250.23 Type 2 diabetes with ophthalmic manifestations Both 130 2066 3 endocrine/metabolic brown 2066, 130 517, 33 516, 26 516, 33 517, 38 0.0659 0.045 0.143 0.8444 1.07 0.978 1.17 -0.23 0.262 0.381 0.4191 0.795 0.475 1.33 -0.0169 0.249 0.946 0.02414 0.983 0.603 1.6 0.139 0.243 0.566 0.2468 1.15 0.714 1.85 PRS_PLINK_0.001 FALSE 250.24 Type 2 diabetes with neurological manifestations Both 51 1073 3 endocrine/metabolic brown 1073, 51 269, 13 268, 16 268, 7 268, 15 0.0715 0.119 0.549 0.2606 1.07 0.85 1.36 0.116 0.366 0.752 0.1237 1.12 0.548 2.3 -0.548 0.439 0.212 0.6731 0.578 0.245 1.37 0.24 0.371 0.518 0.2857 1.27 0.614 2.63 PRS_PLINK_0.001 FALSE 250.4 Abnormal glucose Both 114 1419 3 endocrine/metabolic brown 1419, 114 355, 23 355, 30 354, 20 355, 41 0.0248 0.0583 0.67 0.1737 1.03 0.914 1.15 0.372 0.284 0.19 0.7209 1.45 0.831 2.53 -0.132 0.306 0.666 0.1766 0.876 0.481 1.6 0.591 0.267 0.0271 1.568 1.81 1.07 3.05 PRS_PLINK_0.001 FALSE 250.41 Impaired fasting glucose Both 55 548 3 endocrine/metabolic brown 548, 55 137, 8 137, 10 137, 12 137, 25 0.663 0.315 0.0351 1.454 1.94 1.05 3.6 0.171 0.464 0.713 0.147 1.19 0.478 2.95 0.498 0.444 0.262 0.5809 1.65 0.689 3.93 1.12 0.413 0.00655 2.184 3.07 1.37 6.9 PRS_PLINK_0.001 FALSE 250.42 Other abnormal glucose Both 59 870 3 endocrine/metabolic brown 870, 59 218, 15 217, 20 217, 9 218, 15 0.015 0.0689 0.827 0.0823 1.02 0.887 1.16 0.403 0.348 0.247 0.6073 1.5 0.756 2.96 -0.529 0.411 0.198 0.704 0.589 0.263 1.32 -0.0343 0.364 0.925 0.03386 0.966 0.474 1.97 PRS_PLINK_0.001 FALSE 250.5 Glycosuria or Acetonuria Both 15 283 3 endocrine/metabolic brown 283, 15 71, 2 71, 4 70, 1 71, 8 -1 0.737 0.173 0.761 0.367 0.0866 1.55 0.693 0.719 0.335 0.4747 2 0.489 8.19 -0.296 0.843 0.725 0.1396 0.743 0.142 3.88 1.27 0.689 0.065 1.187 3.57 0.924 13.8 PRS_PLINK_0.001 TRUE 250.6 Polyneuropathy in diabetes Both 30 748 3 endocrine/metabolic brown 748, 30 187, 7 187, 8 187, 4 187, 11 0.0725 0.0948 0.444 0.3521 1.08 0.893 1.29 0.133 0.483 0.783 0.1061 1.14 0.444 2.94 -0.46 0.547 0.4 0.3976 0.631 0.216 1.84 0.473 0.459 0.303 0.5189 1.6 0.653 3.94 PRS_PLINK_0.001 TRUE 250.7 Diabetic retinopathy Both 194 2752 3 endocrine/metabolic brown 2752, 194 688, 48 688, 43 688, 49 688, 54 0.0466 0.043 0.279 0.5552 1.05 0.963 1.14 -0.0971 0.213 0.649 0.1879 0.907 0.598 1.38 0.0381 0.207 0.854 0.06837 1.04 0.692 1.56 0.125 0.204 0.539 0.2684 1.13 0.76 1.69 PRS_PLINK_0.001 FALSE 251.1 Hypoglycemia Both 111 1963 3 endocrine/metabolic brown 1963, 111 491, 21 491, 27 490, 30 491, 33 0.0517 0.0692 0.455 0.3422 1.05 0.92 1.21 0.23 0.289 0.426 0.3706 1.26 0.715 2.22 0.347 0.283 0.219 0.6597 1.42 0.813 2.46 0.435 0.279 0.12 0.9226 1.54 0.894 2.67 PRS_PLINK_0.001 FALSE 252 Disorders of parathyroid gland Both 165 1845 3 endocrine/metabolic brown 1845, 165 462, 36 461, 45 461, 46 461, 38 0.0274 0.102 0.789 0.1029 1.03 0.841 1.26 0.225 0.23 0.327 0.4855 1.25 0.799 1.96 0.236 0.229 0.302 0.5196 1.27 0.809 1.98 0.0558 0.237 0.814 0.08939 1.06 0.664 1.68 PRS_PLINK_0.001 FALSE 252.1 Hyperparathyroidism Both 142 1656 3 endocrine/metabolic brown 1656, 142 414, 30 414, 42 414, 39 414, 31 0.0357 0.1 0.721 0.1418 1.04 0.852 1.26 0.345 0.245 0.159 0.7976 1.41 0.873 2.28 0.23 0.248 0.354 0.4513 1.26 0.774 2.05 0.0296 0.26 0.909 0.04128 1.03 0.619 1.71 PRS_PLINK_0.001 FALSE 252.2 Hypoparathyroidism Both 29 295 3 endocrine/metabolic brown 295, 29 74, 5 74, 6 73, 11 74, 7 0.0562 0.122 0.644 0.1911 1.06 0.834 1.34 0.342 0.577 0.553 0.2569 1.41 0.454 4.36 0.718 0.521 0.169 0.7734 2.05 0.738 5.7 0.278 0.548 0.611 0.2139 1.32 0.452 3.86 PRS_PLINK_0.001 TRUE 253 Disorders of the pituitary gland and its hypothalamic control Both 127 1458 3 endocrine/metabolic brown 1458, 127 365, 34 364, 30 364, 27 365, 36 0.0533 0.0499 0.285 0.5445 1.05 0.956 1.16 -0.141 0.256 0.581 0.2361 0.868 0.526 1.43 -0.195 0.263 0.458 0.3393 0.823 0.492 1.38 0.0732 0.246 0.766 0.1155 1.08 0.664 1.74 PRS_PLINK_0.001 FALSE 253.1 Pituitary hyperfunction Both 33 398 3 endocrine/metabolic brown 398, 33 100, 7 99, 8 99, 5 100, 13 0.136 0.0773 0.0782 1.107 1.15 0.985 1.33 0.000162 0.51 1 0.00011 1 0.368 2.72 -0.384 0.561 0.494 0.3066 0.681 0.227 2.04 0.668 0.476 0.16 0.7955 1.95 0.768 4.95 PRS_PLINK_0.001 TRUE 253.11 Acromegaly and gigantism Both 13 208 3 endocrine/metabolic brown 208, 13 52, 2 52, 3 52, 2 52, 6 1.23 0.9 0.171 0.768 3.43 0.588 20 0.0498 0.763 0.948 0.02323 1.05 0.236 4.69 0.136 0.781 0.862 0.06436 1.15 0.248 5.29 0.95 0.766 0.215 0.6676 2.58 0.576 11.6 PRS_PLINK_0.001 TRUE 253.2 Pituitary hypofunction Both 56 557 3 endocrine/metabolic brown 557, 56 140, 16 139, 17 139, 9 139, 14 0.00686 0.0971 0.944 0.02517 1.01 0.832 1.22 0.00596 0.361 0.987 0.005767 1.01 0.496 2.04 -0.55 0.414 0.184 0.7353 0.577 0.256 1.3 -0.0783 0.382 0.838 0.07691 0.925 0.437 1.96 PRS_PLINK_0.001 FALSE 253.3 Diabetes insipidus Both 21 198 3 endocrine/metabolic brown 198, 21 50, 8 49, 5 49, 6 50, 2 -0.964 0.742 0.194 0.7126 0.382 0.0892 1.63 -0.374 0.566 0.508 0.2941 0.688 0.227 2.08 -0.123 0.56 0.826 0.08295 0.884 0.295 2.65 -1.06 0.671 0.113 0.9463 0.346 0.0929 1.29 PRS_PLINK_0.001 TRUE 253.7 Other disorders of neurohypophysis Both 26 338 3 endocrine/metabolic brown 338, 26 85, 7 84, 4 84, 7 85, 8 0.0485 0.0977 0.619 0.208 1.05 0.867 1.27 -0.491 0.565 0.385 0.4141 0.612 0.202 1.85 0.0404 0.517 0.938 0.02795 1.04 0.378 2.87 0.106 0.5 0.831 0.08016 1.11 0.418 2.96 PRS_PLINK_0.001 TRUE 255 Disorders of adrenal glands Both 117 1389 3 endocrine/metabolic brown 1389, 117 348, 30 347, 27 347, 36 347, 24 -0.000251 0.0915 0.998 0.0009501 1 0.836 1.2 -0.0863 0.269 0.749 0.1257 0.917 0.541 1.56 0.172 0.253 0.498 0.3025 1.19 0.723 1.95 -0.222 0.28 0.426 0.3702 0.801 0.463 1.38 PRS_PLINK_0.001 FALSE 255.1 Adrenal hyperfunction Both 39 409 3 endocrine/metabolic brown 409, 39 103, 11 102, 9 102, 13 102, 6 0.0398 0.123 0.746 0.1275 1.04 0.818 1.32 -0.199 0.448 0.657 0.1826 0.819 0.34 1.97 0.189 0.424 0.656 0.1832 1.21 0.527 2.77 -0.641 0.51 0.208 0.6811 0.527 0.194 1.43 PRS_PLINK_0.001 TRUE 255.11 Cushing's syndrome Both 19 243 3 endocrine/metabolic brown 243, 19 61, 7 61, 6 60, 4 61, 2 -0.678 0.803 0.398 0.3996 0.508 0.105 2.45 0.0509 0.557 0.927 0.03287 1.05 0.353 3.13 -0.588 0.637 0.357 0.4478 0.556 0.159 1.94 -0.805 0.715 0.26 0.5845 0.447 0.11 1.82 PRS_PLINK_0.001 TRUE 255.12 Hyperaldosteronism Both 19 170 3 endocrine/metabolic brown 170, 19 43, 4 42, 2 42, 9 43, 4 0.167 0.817 0.838 0.07659 1.18 0.238 5.86 -0.454 0.747 0.544 0.2646 0.635 0.147 2.75 0.788 0.597 0.187 0.7284 2.2 0.682 7.08 -0.386 0.743 0.603 0.2195 0.68 0.158 2.91 PRS_PLINK_0.001 TRUE 255.2 Adrenal hypofunction Both 71 774 3 endocrine/metabolic brown 774, 71 194, 21 193, 15 193, 21 194, 14 -0.00725 0.097 0.94 0.02669 0.993 0.821 1.2 -0.329 0.344 0.339 0.4692 0.72 0.367 1.41 -0.0266 0.318 0.933 0.02989 0.974 0.522 1.82 -0.377 0.358 0.291 0.5355 0.686 0.34 1.38 PRS_PLINK_0.001 FALSE 255.21 Glucocorticoid deficiency Both 71 772 3 endocrine/metabolic brown 772, 71 193, 21 193, 15 193, 21 193, 14 -0.00827 0.0974 0.932 0.03043 0.992 0.819 1.2 -0.336 0.344 0.33 0.4817 0.715 0.364 1.4 -0.0183 0.318 0.954 0.02041 0.982 0.526 1.83 -0.371 0.357 0.299 0.524 0.69 0.343 1.39 PRS_PLINK_0.001 FALSE 256 Ovarian dysfunction Female 58 555 3 endocrine/metabolic brown 555, 58 139, 11 139, 13 138, 19 139, 15 0.0147 0.0664 0.825 0.08373 1.01 0.891 1.16 0.143 0.413 0.729 0.1372 1.15 0.513 2.59 0.546 0.386 0.157 0.8041 1.73 0.81 3.68 0.247 0.401 0.538 0.2693 1.28 0.583 2.81 PRS_PLINK_0.001 FALSE 256.4 Polycystic ovaries Female 46 511 3 endocrine/metabolic brown 511, 46 128, 9 128, 10 127, 16 128, 11 0.0269 0.0689 0.696 0.1573 1.03 0.897 1.18 0.103 0.463 0.824 0.08394 1.11 0.447 2.75 0.546 0.414 0.188 0.7264 1.73 0.766 3.89 0.159 0.448 0.722 0.1415 1.17 0.488 2.82 PRS_PLINK_0.001 TRUE 257 Testicular dysfunction Male 38 358 3 endocrine/metabolic brown 358, 38 90, 8 89, 10 89, 10 90, 10 0.118 0.553 0.831 0.08033 1.13 0.38 3.33 0.317 0.49 0.517 0.2862 1.37 0.526 3.59 0.121 0.477 0.8 0.09705 1.13 0.443 2.87 0.305 0.487 0.532 0.2741 1.36 0.522 3.52 PRS_PLINK_0.001 TRUE 257.1 Testicular hypofunction Male 31 350 3 endocrine/metabolic brown 350, 31 88, 6 87, 8 87, 8 88, 9 0.265 0.605 0.661 0.1797 1.3 0.398 4.27 0.519 0.545 0.341 0.4677 1.68 0.578 4.89 0.146 0.528 0.782 0.1066 1.16 0.411 3.25 0.402 0.526 0.444 0.3525 1.5 0.534 4.19 PRS_PLINK_0.001 TRUE 258 Iatrogenic endocrine disorders Both 22 221 3 endocrine/metabolic brown 221, 22 56, 8 55, 8 55, 2 55, 4 -1.22 0.776 0.117 0.933 0.296 0.0647 1.35 -0.0387 0.524 0.941 0.0264 0.962 0.345 2.69 -0.951 0.734 0.195 0.7098 0.386 0.0916 1.63 -0.998 0.66 0.13 0.8849 0.369 0.101 1.34 PRS_PLINK_0.001 TRUE 259 Other endocrine disorders Both 30 320 3 endocrine/metabolic brown 320, 30 80, 6 80, 6 80, 11 80, 7 0.128 0.077 0.0951 1.022 1.14 0.978 1.32 -0.0853 0.565 0.88 0.05556 0.918 0.304 2.78 0.543 0.501 0.278 0.5561 1.72 0.645 4.59 0.242 0.546 0.657 0.1825 1.27 0.437 3.71 PRS_PLINK_0.001 TRUE 260 Protein-calorie malnutrition Both 32 378 3 endocrine/metabolic brown 378, 32 95, 4 94, 10 94, 7 95, 11 0.583 0.468 0.213 0.6718 1.79 0.716 4.49 0.9 0.583 0.123 0.9116 2.46 0.785 7.71 0.313 0.612 0.609 0.2156 1.37 0.412 4.54 0.838 0.548 0.126 0.8987 2.31 0.79 6.76 PRS_PLINK_0.001 TRUE 260.1 Cachexia Both 5 96 3 endocrine/metabolic brown 96, 5 24, 1 24, 0 24, 2 24, 2 1.52 1.23 0.218 0.6612 4.57 0.407 51.3 -0.95 1.16 0.415 0.3822 0.387 0.0394 3.79 1.01 1.1 0.361 0.4429 2.74 0.315 23.8 0.733 0.99 0.459 0.338 2.08 0.299 14.5 PRS_PLINK_0.001 TRUE 260.6 Anorexia Both 137 1714 3 endocrine/metabolic brown 1714, 137 429, 32 428, 33 428, 28 429, 44 0.0241 0.0612 0.694 0.1585 1.02 0.909 1.15 0.0065 0.252 0.979 0.009015 1.01 0.614 1.65 -0.166 0.261 0.525 0.2802 0.847 0.507 1.41 0.334 0.238 0.161 0.7943 1.4 0.876 2.23 PRS_PLINK_0.001 FALSE 261 Vitamin deficiency Both 176 2504 3 endocrine/metabolic brown 2504, 176 626, 45 626, 32 626, 52 626, 47 0.0376 0.0746 0.614 0.2116 1.04 0.897 1.2 -0.322 0.235 0.169 0.7713 0.724 0.457 1.15 0.134 0.208 0.52 0.2837 1.14 0.76 1.72 0.0247 0.214 0.908 0.04187 1.03 0.674 1.56 PRS_PLINK_0.001 FALSE 261.2 Vitamin B-complex deficiencies Both 101 1545 3 endocrine/metabolic brown 1545, 101 387, 22 386, 19 386, 35 386, 25 0.0384 0.0742 0.605 0.2185 1.04 0.898 1.2 -0.179 0.312 0.566 0.2469 0.836 0.454 1.54 0.457 0.274 0.096 1.018 1.58 0.922 2.7 0.132 0.293 0.652 0.1856 1.14 0.642 2.03 PRS_PLINK_0.001 FALSE 261.4 Vitamin D deficiency Both 75 980 3 endocrine/metabolic brown 980, 75 245, 24 245, 13 245, 16 245, 22 0.109 0.116 0.349 0.4575 1.12 0.888 1.4 -0.594 0.343 0.0836 1.078 0.552 0.282 1.08 -0.427 0.325 0.189 0.7241 0.653 0.345 1.23 -0.157 0.304 0.605 0.2185 0.854 0.471 1.55 PRS_PLINK_0.001 FALSE 261.41 Rickets or osteomalacia Both 11 161 3 endocrine/metabolic brown 161, 11 41, 3 40, 3 40, 1 40, 4 -0.125 0.974 0.898 0.04658 0.883 0.131 5.96 -0.0675 0.738 0.927 0.03287 0.935 0.22 3.97 -1.01 1.08 0.349 0.457 0.365 0.0443 3.01 0.631 0.906 0.486 0.3132 1.88 0.318 11.1 PRS_PLINK_0.001 TRUE 262 Mineral deficiency NEC Both 36 483 3 endocrine/metabolic brown 483, 36 121, 9 121, 6 120, 6 121, 15 0.155 0.0546 0.00437 2.359 1.17 1.05 1.3 -0.397 0.502 0.428 0.3681 0.672 0.251 1.8 -0.389 0.505 0.441 0.356 0.678 0.252 1.82 0.597 0.425 0.16 0.7952 1.82 0.789 4.18 PRS_PLINK_0.001 TRUE 269 Proteinuria Both 58 707 3 endocrine/metabolic brown 707, 58 177, 10 177, 17 176, 11 177, 20 0.0553 0.0694 0.426 0.3708 1.06 0.922 1.21 0.433 0.395 0.273 0.5633 1.54 0.71 3.35 0.203 0.438 0.643 0.1915 1.22 0.519 2.89 0.659 0.388 0.0898 1.047 1.93 0.903 4.14 PRS_PLINK_0.001 FALSE 270 Disorders of protein plasma/amino-acid transport and metabolism Both 56 616 3 endocrine/metabolic brown 616, 56 154, 14 154, 16 154, 10 154, 16 0.0657 0.0517 0.204 0.6904 1.07 0.965 1.18 0.132 0.367 0.72 0.1428 1.14 0.555 2.34 -0.276 0.41 0.5 0.3007 0.759 0.34 1.69 0.16 0.371 0.667 0.1756 1.17 0.566 2.43 PRS_PLINK_0.001 FALSE 270.3 Disorders of plasma protein metabolism Both 48 525 3 endocrine/metabolic brown 525, 48 132, 14 131, 12 131, 7 131, 15 0.188 0.121 0.12 0.9208 1.21 0.952 1.53 -0.175 0.393 0.657 0.1824 0.84 0.389 1.81 -0.617 0.448 0.169 0.7725 0.54 0.224 1.3 0.136 0.379 0.719 0.1435 1.15 0.545 2.41 PRS_PLINK_0.001 TRUE 270.32 Paraproteinemia Both 31 386 3 endocrine/metabolic brown 386, 31 97, 14 96, 5 96, 3 97, 9 0.181 0.116 0.12 0.9207 1.2 0.954 1.51 -0.831 0.501 0.0973 1.012 0.436 0.163 1.16 -1.24 0.584 0.0337 1.472 0.289 0.0921 0.909 -0.285 0.438 0.516 0.2871 0.752 0.319 1.78 PRS_PLINK_0.001 TRUE 270.33 Amyloidosis Both 21 229 3 endocrine/metabolic brown 229, 21 58, 6 57, 6 57, 2 57, 7 -0.599 0.767 0.435 0.3619 0.549 0.122 2.47 -0.815 0.68 0.231 0.6371 0.443 0.117 1.68 -1.01 0.704 0.15 0.8246 0.363 0.0913 1.44 0.089 0.578 0.878 0.05668 1.09 0.352 3.39 PRS_PLINK_0.001 TRUE 270.35 Macroglobulinemia Both 15 136 3 endocrine/metabolic brown 136, 15 34, 2 34, 3 34, 4 34, 6 1.24 0.909 0.174 0.7606 3.44 0.58 20.4 0.768 0.891 0.389 0.4106 2.16 0.376 12.3 0.388 0.837 0.643 0.1917 1.47 0.286 7.61 1.27 0.791 0.109 0.9612 3.55 0.753 16.7 PRS_PLINK_0.001 TRUE 271 Disorders of carbohydrate transport and metabolism Both 30 314 3 endocrine/metabolic brown 314, 30 79, 8 78, 8 78, 7 79, 7 -0.246 0.663 0.71 0.1486 0.782 0.213 2.87 0.0222 0.498 0.965 0.01568 1.02 0.385 2.72 -0.0316 0.525 0.952 0.02131 0.969 0.346 2.71 -0.165 0.527 0.754 0.1225 0.848 0.302 2.38 PRS_PLINK_0.001 TRUE 271.3 Intestinal disaccharidase deficiencies and disaccharide malabsorption Both 25 271 3 endocrine/metabolic brown 271, 25 68, 5 68, 8 67, 6 68, 6 -0.278 0.755 0.712 0.1475 0.757 0.173 3.32 0.411 0.544 0.45 0.3471 1.51 0.52 4.38 0.193 0.592 0.745 0.1281 1.21 0.38 3.87 0.0122 0.594 0.984 0.007211 1.01 0.316 3.24 PRS_PLINK_0.001 TRUE 272 Disorders of lipoid metabolism Both 6108 50760 3 endocrine/metabolic brown 50760, 6108 12689, 1502 12690, 1555 12690, 1515 12690, 1536 0.00694 0.0123 0.574 0.2409 1.01 0.983 1.03 0.0381 0.0386 0.324 0.49 1.04 0.963 1.12 0.0131 0.0388 0.737 0.1328 1.01 0.939 1.09 0.0282 0.0387 0.466 0.3312 1.03 0.953 1.11 PRS_PLINK_0.001 FALSE 272.1 Hyperlipidemia Both 6092 50708 3 endocrine/metabolic brown 50708, 6092 12676, 1499 12677, 1552 12677, 1510 12677, 1531 0.0069 0.0124 0.576 0.2393 1.01 0.983 1.03 0.0381 0.0386 0.325 0.4886 1.04 0.963 1.12 0.0117 0.0389 0.764 0.1169 1.01 0.938 1.09 0.0267 0.0388 0.491 0.3092 1.03 0.952 1.11 PRS_PLINK_0.001 FALSE 272.11 Hypercholesterolemia Both 5653 49046 3 endocrine/metabolic brown 49046, 5653 12261, 1384 12261, 1430 12261, 1406 12262, 1433 0.0114 0.0123 0.355 0.4501 1.01 0.987 1.04 0.0355 0.0401 0.376 0.4253 1.04 0.958 1.12 0.0184 0.0402 0.647 0.1889 1.02 0.941 1.1 0.0394 0.0401 0.325 0.4884 1.04 0.962 1.13 PRS_PLINK_0.001 FALSE 272.12 Hyperglyceridemia Both 8 116 3 endocrine/metabolic brown 116, 8 29, 3 29, 2 29, 1 29, 2 -0.308 1.15 0.789 0.1031 0.735 0.0773 6.98 -0.258 0.817 0.753 0.1234 0.773 0.156 3.84 -1.23 1.15 0.283 0.5489 0.291 0.0307 2.76 PRS_PLINK_0.001 TRUE 272.13 Mixed hyperlipidemia Both 22 353 3 endocrine/metabolic brown 353, 22 89, 1 88, 8 88, 8 88, 5 0.0293 0.0689 0.67 0.1737 1.03 0.9 1.18 1.71 0.817 0.0364 1.439 5.52 1.11 27.4 1.66 0.786 0.0342 1.467 5.28 1.13 24.6 1.28 0.78 0.101 0.9974 3.6 0.78 16.6 PRS_PLINK_0.001 TRUE 272.9 Unspecified disorder of lipoid metabolism Both 34 434 3 endocrine/metabolic brown 434, 34 109, 6 108, 3 108, 13 109, 12 0.0992 0.111 0.371 0.4308 1.1 0.889 1.37 -0.58 0.629 0.357 0.4479 0.56 0.163 1.92 0.852 0.504 0.0907 1.042 2.35 0.874 6.3 0.704 0.492 0.152 0.8178 2.02 0.771 5.3 PRS_PLINK_0.001 TRUE 274 Gout and other crystal arthropathies Both 641 7785 3 endocrine/metabolic brown 7785, 641 1947, 185 1946, 163 1946, 133 1946, 160 0.0111 0.0377 0.768 0.1147 1.01 0.939 1.09 -0.131 0.112 0.24 0.62 0.877 0.704 1.09 -0.333 0.118 0.00472 2.326 0.717 0.569 0.903 -0.15 0.112 0.183 0.7382 0.861 0.691 1.07 PRS_PLINK_0.001 FALSE 274.1 Gout Both 550 6621 3 endocrine/metabolic brown 6621, 550 1656, 152 1655, 140 1655, 115 1655, 143 0.0246 0.0368 0.505 0.2969 1.02 0.954 1.1 -0.0915 0.122 0.452 0.3446 0.913 0.719 1.16 -0.278 0.128 0.0294 1.532 0.757 0.589 0.972 -0.0616 0.121 0.611 0.2141 0.94 0.742 1.19 PRS_PLINK_0.001 FALSE 274.11 Gouty arthropathy Both 15 240 3 endocrine/metabolic brown 240, 15 60, 1 60, 4 60, 4 60, 6 0.497 0.536 0.354 0.4513 1.64 0.575 4.7 0.716 0.828 0.387 0.4122 2.05 0.404 10.4 0.817 0.842 0.332 0.4794 2.26 0.435 11.8 1.61 0.855 0.0593 1.227 5.02 0.939 26.8 PRS_PLINK_0.001 TRUE 274.2 Crystal arthropathies Both 104 1280 3 endocrine/metabolic brown 1280, 104 320, 35 320, 25 320, 22 320, 22 -0.414 0.342 0.226 0.6461 0.661 0.338 1.29 -0.39 0.27 0.148 0.8296 0.677 0.399 1.15 -0.475 0.276 0.0851 1.07 0.622 0.362 1.07 -0.469 0.277 0.0912 1.04 0.626 0.363 1.08 PRS_PLINK_0.001 FALSE 274.21 Chondrocalcinosis Both 98 1174 3 endocrine/metabolic brown 1174, 98 294, 33 293, 24 293, 20 294, 21 -0.451 0.356 0.205 0.6887 0.637 0.317 1.28 -0.388 0.278 0.162 0.7897 0.678 0.393 1.17 -0.5 0.287 0.0814 1.089 0.607 0.346 1.06 -0.447 0.284 0.115 0.938 0.64 0.367 1.12 PRS_PLINK_0.001 FALSE 275 Disorders of mineral metabolism Both 365 4338 3 endocrine/metabolic brown 4338, 365 1085, 90 1084, 98 1084, 81 1085, 96 0.048 0.0535 0.37 0.4318 1.05 0.945 1.17 0.0983 0.152 0.517 0.2867 1.1 0.82 1.49 -0.102 0.158 0.519 0.2848 0.903 0.663 1.23 0.0526 0.152 0.729 0.1373 1.05 0.783 1.42 PRS_PLINK_0.001 FALSE 275.1 Disorders of iron metabolism Both 122 1374 4 hematopoietic darkorange1 1374, 122 344, 30 343, 33 343, 22 344, 37 0.0243 0.0966 0.801 0.09619 1.02 0.848 1.24 0.0929 0.259 0.72 0.1425 1.1 0.66 1.82 -0.291 0.284 0.306 0.5143 0.747 0.428 1.31 0.229 0.252 0.365 0.4374 1.26 0.766 2.06 PRS_PLINK_0.001 FALSE 275.3 Disorders of magnesium metabolism Both 55 765 3 endocrine/metabolic brown 765, 55 192, 12 191, 17 191, 16 191, 10 -0.189 0.458 0.68 0.1676 0.828 0.338 2.03 0.395 0.374 0.291 0.5355 1.48 0.713 3.09 0.323 0.377 0.392 0.4065 1.38 0.659 2.89 -0.181 0.419 0.666 0.1766 0.834 0.367 1.9 PRS_PLINK_0.001 FALSE 275.5 Disorders of calcium/phosphorus metabolism Both 207 2473 3 endocrine/metabolic brown 2473, 207 619, 53 618, 54 618, 48 618, 52 0.0947 0.0637 0.137 0.8635 1.1 0.97 1.25 0.0382 0.199 0.848 0.07168 1.04 0.703 1.54 -0.0931 0.204 0.649 0.188 0.911 0.611 1.36 -0.036 0.201 0.858 0.06652 0.965 0.651 1.43 PRS_PLINK_0.001 FALSE 275.53 Disorders of phosphorus metabolism Both 26 371 3 endocrine/metabolic brown 371, 26 93, 9 93, 4 92, 6 93, 7 0.186 0.117 0.111 0.9536 1.2 0.958 1.52 -0.686 0.554 0.216 0.6662 0.504 0.17 1.49 -0.306 0.504 0.544 0.2647 0.736 0.274 1.98 -0.182 0.497 0.714 0.146 0.834 0.315 2.21 PRS_PLINK_0.001 TRUE 276 Disorders of fluid, electrolyte, and acid-base balance Both 1073 15005 3 endocrine/metabolic brown 15005, 1073 3752, 264 3751, 261 3751, 288 3751, 260 -0.0317 0.041 0.439 0.3571 0.969 0.894 1.05 -0.0157 0.0901 0.862 0.06462 0.984 0.825 1.17 0.0806 0.0881 0.36 0.4437 1.08 0.912 1.29 -0.0178 0.0902 0.844 0.07375 0.982 0.823 1.17 PRS_PLINK_0.001 FALSE 276.1 Electrolyte imbalance Both 575 8424 3 endocrine/metabolic brown 8424, 575 2106, 152 2106, 136 2106, 155 2106, 132 -0.0164 0.0463 0.724 0.1403 0.984 0.898 1.08 -0.12 0.121 0.322 0.492 0.887 0.699 1.12 0.0146 0.118 0.901 0.04509 1.01 0.806 1.28 -0.143 0.122 0.241 0.6181 0.866 0.682 1.1 PRS_PLINK_0.001 FALSE 276.11 Hyperosmolality and/or hypernatremia Both 23 519 3 endocrine/metabolic brown 519, 23 130, 6 130, 6 129, 6 130, 5 -0.21 0.677 0.756 0.1215 0.81 0.215 3.05 -0.0408 0.554 0.941 0.02624 0.96 0.324 2.84 -0.156 0.553 0.777 0.1093 0.855 0.29 2.53 -0.316 0.558 0.571 0.243 0.729 0.244 2.18 PRS_PLINK_0.001 TRUE 276.12 Hyposmolality and/or hyponatremia Both 257 3722 3 endocrine/metabolic brown 3722, 257 931, 65 930, 62 930, 76 931, 54 0.0169 0.052 0.745 0.1278 1.02 0.918 1.13 -0.0556 0.181 0.759 0.1196 0.946 0.663 1.35 0.154 0.174 0.375 0.4265 1.17 0.83 1.64 -0.178 0.187 0.343 0.4645 0.837 0.58 1.21 PRS_PLINK_0.001 FALSE 276.13 Hyperpotassemia Both 134 1984 3 endocrine/metabolic brown 1984, 134 496, 28 496, 25 496, 46 496, 35 0.0596 0.0763 0.435 0.3618 1.06 0.914 1.23 -0.148 0.275 0.59 0.2288 0.862 0.503 1.48 0.485 0.243 0.0462 1.335 1.62 1.01 2.62 0.188 0.257 0.463 0.3347 1.21 0.73 2 PRS_PLINK_0.001 FALSE 276.14 Hypopotassemia Both 210 2926 3 endocrine/metabolic brown 2926, 210 732, 62 731, 50 731, 51 732, 47 -0.0457 0.098 0.641 0.1929 0.955 0.788 1.16 -0.196 0.195 0.315 0.5019 0.822 0.56 1.21 -0.217 0.194 0.264 0.5776 0.805 0.55 1.18 -0.299 0.199 0.133 0.8766 0.742 0.502 1.1 PRS_PLINK_0.001 FALSE 276.4 Acid-base balance disorder Both 162 2326 3 endocrine/metabolic brown 2326, 162 582, 43 581, 25 581, 47 582, 47 0.0442 0.0786 0.574 0.2409 1.05 0.896 1.22 -0.517 0.252 0.0403 1.395 0.597 0.364 0.977 0.1 0.216 0.643 0.1921 1.11 0.724 1.69 0.0758 0.217 0.727 0.1385 1.08 0.705 1.65 PRS_PLINK_0.001 FALSE 276.41 Acidosis Both 140 2092 3 endocrine/metabolic brown 2092, 140 523, 38 523, 19 523, 41 523, 42 0.047 0.0803 0.558 0.2532 1.05 0.895 1.23 -0.658 0.279 0.0183 1.738 0.518 0.3 0.894 0.084 0.229 0.714 0.1461 1.09 0.694 1.71 0.0977 0.23 0.672 0.173 1.1 0.702 1.73 PRS_PLINK_0.001 FALSE 276.42 Alkalosis Both 21 253 3 endocrine/metabolic brown 253, 21 64, 4 63, 7 63, 6 63, 4 0.23 0.325 0.479 0.3196 1.26 0.666 2.38 0.592 0.598 0.322 0.4926 1.81 0.56 5.83 0.456 0.612 0.456 0.3413 1.58 0.476 5.23 0.116 0.649 0.858 0.06645 1.12 0.315 4 PRS_PLINK_0.001 TRUE 276.5 Hypovolemia Both 431 5827 3 endocrine/metabolic brown 5827, 431 1457, 99 1457, 118 1456, 111 1457, 103 -0.0466 0.0811 0.565 0.2478 0.954 0.814 1.12 0.171 0.14 0.223 0.6516 1.19 0.901 1.56 0.0989 0.142 0.487 0.3124 1.1 0.835 1.46 0.0311 0.145 0.83 0.08108 1.03 0.777 1.37 PRS_PLINK_0.001 FALSE 276.6 Fluid overload Both 71 938 3 endocrine/metabolic brown 938, 71 235, 11 234, 14 234, 20 235, 26 0.0811 0.0863 0.347 0.4592 1.08 0.916 1.28 0.254 0.39 0.515 0.2884 1.29 0.6 2.77 0.445 0.372 0.232 0.6354 1.56 0.753 3.24 0.838 0.359 0.0194 1.712 2.31 1.14 4.67 PRS_PLINK_0.001 FALSE 276.8 Polydipsia Both 18 261 3 endocrine/metabolic brown 261, 18 66, 6 65, 2 65, 7 65, 3 -0.621 0.758 0.413 0.3845 0.537 0.121 2.38 -0.789 0.688 0.251 0.5995 0.454 0.118 1.75 -0.057 0.581 0.922 0.03537 0.945 0.303 2.95 -0.384 0.67 0.566 0.247 0.681 0.183 2.53 PRS_PLINK_0.001 TRUE 277 Other disorders of metabolism Both 137 1862 3 endocrine/metabolic brown 1862, 137 466, 27 465, 35 465, 41 466, 34 0.0267 0.0702 0.703 0.1529 1.03 0.895 1.18 0.249 0.259 0.337 0.4728 1.28 0.772 2.13 0.433 0.251 0.084 1.076 1.54 0.943 2.52 0.231 0.26 0.376 0.4254 1.26 0.756 2.1 PRS_PLINK_0.001 FALSE 277.4 Disorders of bilirubin excretion Both 59 761 3 endocrine/metabolic brown 761, 59 191, 13 190, 16 190, 8 190, 22 0.216 0.0986 0.0282 1.55 1.24 1.02 1.51 0.228 0.374 0.542 0.2659 1.26 0.604 2.61 -0.689 0.447 0.123 0.9114 0.502 0.209 1.2 0.465 0.353 0.188 0.726 1.59 0.797 3.18 PRS_PLINK_0.001 FALSE 277.5 Other disorders of lipoid metabolism Both 34 470 3 endocrine/metabolic brown 470, 34 118, 12 117, 8 117, 9 118, 5 -0.505 0.586 0.388 0.4107 0.603 0.191 1.9 -0.428 0.447 0.338 0.4716 0.652 0.271 1.56 -0.307 0.446 0.491 0.3085 0.736 0.307 1.76 -0.884 0.503 0.0787 1.104 0.413 0.154 1.11 PRS_PLINK_0.001 TRUE 277.51 Lipoprotein disorders Both 5 103 3 endocrine/metabolic brown 103, 5 26, 2 26, 1 25, 2 26, 0 -1.42 1.22 0.245 0.6101 0.242 0.0221 2.65 -0.536 0.97 0.58 0.2363 0.585 0.0875 3.91 -0.522 1.09 0.632 0.1991 0.593 0.07 5.03 -1.96 1.4 0.161 0.7923 0.141 0.00908 2.19 PRS_PLINK_0.001 TRUE 278 Overweight, obesity and other hyperalimentation Both 1800 23168 3 endocrine/metabolic brown 23168, 1800 5792, 414 5792, 460 5792, 492 5792, 434 0.0143 0.0216 0.508 0.2938 1.01 0.972 1.06 0.104 0.0701 0.137 0.8638 1.11 0.967 1.27 0.174 0.0692 0.0119 1.925 1.19 1.04 1.36 0.0491 0.0711 0.49 0.3102 1.05 0.914 1.21 PRS_PLINK_0.001 FALSE 278.1 Obesity Both 1771 22815 3 endocrine/metabolic brown 22815, 1771 5704, 410 5704, 451 5703, 481 5704, 429 0.0173 0.022 0.431 0.3656 1.02 0.975 1.06 0.0946 0.0707 0.18 0.7438 1.1 0.957 1.26 0.161 0.0697 0.0207 1.683 1.17 1.02 1.35 0.047 0.0715 0.511 0.2919 1.05 0.911 1.21 PRS_PLINK_0.001 FALSE 278.3 Localized adiposity Both 15 201 3 endocrine/metabolic brown 201, 15 51, 2 50, 3 50, 8 50, 2 -5.49 0.949 7.41e-09 8.13 0.00414 0.000644 0.0266 0.0969 0.806 0.904 0.04365 1.1 0.227 5.35 1.04 0.686 0.13 0.8864 2.83 0.737 10.8 0.663 0.921 0.472 0.3265 1.94 0.319 11.8 PRS_PLINK_0.001 TRUE 278.4 Abnormal weight gain Both 18 152 3 endocrine/metabolic brown 152, 18 38, 5 38, 6 38, 3 38, 4 -0.239 0.836 0.775 0.1108 0.787 0.153 4.06 0.193 0.601 0.748 0.1263 1.21 0.373 3.94 -0.46 0.68 0.499 0.302 0.631 0.167 2.39 -0.0492 0.71 0.945 0.02467 0.952 0.237 3.83 PRS_PLINK_0.001 TRUE 279 Disorders involving the immune mechanism Both 52 537 3 endocrine/metabolic brown 537, 52 135, 8 134, 16 134, 13 134, 15 0.0786 0.112 0.483 0.3158 1.08 0.868 1.35 0.648 0.431 0.133 0.8766 1.91 0.821 4.45 0.351 0.448 0.433 0.3632 1.42 0.591 3.41 0.656 0.432 0.129 0.8904 1.93 0.827 4.49 PRS_PLINK_0.001 FALSE 279.1 Immunity deficiency Both 43 449 3 endocrine/metabolic brown 449, 43 113, 8 112, 14 112, 11 112, 10 0.0471 0.0979 0.63 0.2005 1.05 0.865 1.27 0.479 0.445 0.281 0.5512 1.61 0.676 3.86 0.274 0.462 0.554 0.2567 1.31 0.531 3.26 0.207 0.464 0.655 0.1836 1.23 0.496 3.05 PRS_PLINK_0.001 TRUE 279.11 Deficiency of humoral immunity Both 31 303 3 endocrine/metabolic brown 303, 31 76, 7 76, 8 75, 10 76, 6 0.0202 0.104 0.846 0.07244 1.02 0.832 1.25 -0.0288 0.509 0.955 0.02006 0.972 0.358 2.63 0.192 0.5 0.702 0.1538 1.21 0.454 3.23 -0.194 0.533 0.716 0.1454 0.823 0.29 2.34 PRS_PLINK_0.001 TRUE 279.7 Other immunological findings Both 52 520 3 endocrine/metabolic brown 520, 52 130, 20 130, 11 130, 12 130, 9 -1.04 0.501 0.0384 1.416 0.354 0.133 0.946 -0.596 0.384 0.12 0.9191 0.551 0.26 1.17 -0.564 0.378 0.136 0.8659 0.569 0.271 1.19 -0.807 0.409 0.0486 1.313 0.446 0.2 0.995 PRS_PLINK_0.001 FALSE 280 Iron deficiency anemias Both 1361 16155 4 hematopoietic darkorange1 16155, 1361 4039, 327 4039, 333 4038, 363 4039, 338 -0.0202 0.0329 0.54 0.2677 0.98 0.919 1.05 0.0211 0.0808 0.794 0.1002 1.02 0.872 1.2 0.105 0.0793 0.185 0.7338 1.11 0.951 1.3 0.0325 0.0805 0.686 0.1635 1.03 0.882 1.21 PRS_PLINK_0.001 FALSE 280.1 Iron deficiency anemias, unspecified or not due to blood loss Both 1306 15495 4 hematopoietic darkorange1 15495, 1306 3874, 311 3874, 320 3873, 343 3874, 332 -0.0117 0.0326 0.719 0.1433 0.988 0.927 1.05 0.0295 0.0827 0.721 0.1422 1.03 0.876 1.21 0.097 0.0814 0.234 0.6314 1.1 0.939 1.29 0.0639 0.082 0.435 0.3611 1.07 0.908 1.25 PRS_PLINK_0.001 FALSE 280.2 Iron deficiency anemia secondary to blood loss (chronic) Both 79 1020 4 hematopoietic darkorange1 1020, 79 255, 19 255, 19 255, 28 255, 13 0.0371 0.103 0.718 0.144 1.04 0.849 1.27 -0.0754 0.33 0.819 0.08664 0.927 0.486 1.77 0.378 0.303 0.211 0.675 1.46 0.807 2.64 -0.367 0.356 0.302 0.5205 0.693 0.345 1.39 PRS_PLINK_0.001 FALSE 281 Other deficiency anemia Both 174 2248 4 hematopoietic darkorange1 2248, 174 562, 53 562, 31 562, 40 562, 50 0.0179 0.0672 0.79 0.1023 1.02 0.892 1.16 -0.539 0.23 0.019 1.72 0.583 0.372 0.915 -0.291 0.215 0.176 0.755 0.748 0.491 1.14 -0.0601 0.204 0.769 0.1143 0.942 0.631 1.41 PRS_PLINK_0.001 FALSE 281.1 Megaloblastic anemia Both 165 2141 4 hematopoietic darkorange1 2141, 165 536, 51 535, 30 535, 36 535, 48 0.0162 0.0683 0.812 0.09046 1.02 0.889 1.16 -0.527 0.234 0.0244 1.612 0.59 0.373 0.934 -0.347 0.223 0.12 0.922 0.707 0.457 1.09 -0.0682 0.208 0.743 0.1288 0.934 0.621 1.4 PRS_PLINK_0.001 FALSE 281.11 Pernicious anemia Both 109 1483 4 hematopoietic darkorange1 1483, 109 371, 37 371, 17 370, 21 371, 34 0.0224 0.067 0.738 0.1321 1.02 0.897 1.17 -0.743 0.294 0.0115 1.941 0.476 0.268 0.846 -0.522 0.276 0.0586 1.232 0.594 0.346 1.02 -0.0859 0.244 0.725 0.1396 0.918 0.568 1.48 PRS_PLINK_0.001 FALSE 281.12 Other vitamin B12 deficiency anemia Both 34 322 4 hematopoietic darkorange1 322, 34 81, 11 80, 5 80, 7 81, 11 0.0101 0.12 0.932 0.03037 1.01 0.799 1.28 -0.542 0.575 0.346 0.4614 0.582 0.189 1.79 -0.274 0.509 0.59 0.2294 0.76 0.281 2.06 0.00391 0.468 0.993 0.002904 1 0.401 2.51 PRS_PLINK_0.001 TRUE 281.13 Folate-deficiency anemia Both 29 403 4 hematopoietic darkorange1 403, 29 101, 9 101, 8 100, 8 101, 4 -0.909 0.611 0.137 0.8642 0.403 0.122 1.33 -0.0449 0.483 0.926 0.03347 0.956 0.371 2.46 -0.178 0.482 0.712 0.1475 0.837 0.326 2.15 -0.791 0.563 0.16 0.7948 0.454 0.15 1.37 PRS_PLINK_0.001 TRUE 281.9 Deficiency anemias Both 8 115 4 hematopoietic darkorange1 115, 8 29, 1 29, 2 28, 3 29, 2 1.17 1.1 0.286 0.5444 3.23 0.375 27.9 0.322 1.02 0.752 0.1239 1.38 0.188 10.1 0.988 1.01 0.329 0.4828 2.69 0.369 19.5 0.38 0.974 0.696 0.1571 1.46 0.217 9.86 PRS_PLINK_0.001 TRUE 282 Hereditary hemolytic anemias Both 37 328 4 hematopoietic darkorange1 328, 37 82, 7 82, 7 82, 13 82, 10 0.119 0.0751 0.112 0.9516 1.13 0.973 1.31 -0.0671 0.533 0.9 0.04589 0.935 0.329 2.66 0.472 0.47 0.315 0.5018 1.6 0.638 4.03 0.419 0.499 0.401 0.397 1.52 0.572 4.04 PRS_PLINK_0.001 TRUE 282.8 Other hemoglobinopathies Both 16 118 4 hematopoietic darkorange1 118, 16 30, 2 29, 1 29, 8 30, 5 1.26 0.91 0.165 0.782 3.54 0.594 21 -0.563 0.912 0.537 0.2701 0.569 0.0953 3.4 1.84 0.893 0.0392 1.407 6.31 1.1 36.3 0.691 0.767 0.368 0.4343 2 0.444 8.98 PRS_PLINK_0.001 TRUE 282.9 Other hereditary hemolytic anemias Both 19 173 4 hematopoietic darkorange1 173, 19 44, 4 43, 5 43, 4 43, 6 4.16 0.819 3.72e-07 6.43 64.2 12.9 320 0.185 0.643 0.773 0.1117 1.2 0.341 4.24 -0.176 0.664 0.792 0.1015 0.839 0.228 3.08 0.23 0.653 0.725 0.1399 1.26 0.35 4.52 PRS_PLINK_0.001 TRUE 283 Acquired hemolytic anemias Both 16 261 4 hematopoietic darkorange1 261, 16 66, 5 65, 4 65, 6 65, 1 -0.549 0.806 0.495 0.3051 0.577 0.119 2.8 -0.268 0.619 0.665 0.1769 0.765 0.227 2.57 0.361 0.617 0.558 0.2534 1.44 0.429 4.81 -1.25 0.808 0.122 0.9148 0.286 0.0587 1.4 PRS_PLINK_0.001 TRUE 283.1 Autoimmune hemolytic anemias Both 17 204 4 hematopoietic darkorange1 204, 17 51, 5 51, 4 51, 6 51, 2 -0.307 0.816 0.706 0.1511 0.735 0.149 3.64 -0.24 0.634 0.705 0.1516 0.787 0.227 2.72 0.193 0.618 0.755 0.1223 1.21 0.361 4.07 -0.681 0.719 0.343 0.4641 0.506 0.124 2.07 PRS_PLINK_0.001 TRUE 284 Aplastic anemia Both 78 936 4 hematopoietic darkorange1 936, 78 234, 23 234, 21 234, 15 234, 19 0.0279 0.107 0.795 0.09988 1.03 0.834 1.27 -0.12 0.307 0.695 0.1579 0.887 0.485 1.62 -0.376 0.333 0.258 0.5877 0.687 0.358 1.32 -0.0662 0.317 0.835 0.07847 0.936 0.503 1.74 PRS_PLINK_0.001 FALSE 285 Other anemias Both 2111 25299 4 hematopoietic darkorange1 25299, 2111 6325, 505 6325, 548 6324, 518 6325, 540 0.0117 0.0186 0.53 0.2757 1.01 0.976 1.05 0.0805 0.0641 0.209 0.6793 1.08 0.956 1.23 0.0286 0.065 0.66 0.1804 1.03 0.906 1.17 0.0685 0.0644 0.288 0.5413 1.07 0.944 1.21 PRS_PLINK_0.001 FALSE 285.1 Acute posthemorrhagic anemia Both 43 601 4 hematopoietic darkorange1 601, 43 151, 12 150, 13 150, 9 150, 9 0.0112 0.0899 0.901 0.0455 1.01 0.848 1.21 0.0307 0.404 0.939 0.02712 1.03 0.467 2.28 -0.216 0.431 0.616 0.2101 0.806 0.346 1.88 -0.303 0.427 0.478 0.3204 0.739 0.32 1.71 PRS_PLINK_0.001 TRUE 285.2 Anemia of chronic disease Both 105 1388 4 hematopoietic darkorange1 1388, 105 347, 25 347, 25 347, 29 347, 26 0.0213 0.0854 0.803 0.09546 1.02 0.864 1.21 -0.0297 0.285 0.917 0.03758 0.971 0.555 1.7 0.114 0.277 0.681 0.1667 1.12 0.651 1.93 0.0221 0.283 0.938 0.02786 1.02 0.587 1.78 PRS_PLINK_0.001 FALSE 285.22 Anemia in neoplastic disease Both 66 812 4 hematopoietic darkorange1 812, 66 203, 12 203, 14 203, 21 203, 19 0.0447 0.0907 0.622 0.2065 1.05 0.876 1.25 0.0638 0.393 0.871 0.05998 1.07 0.493 2.3 0.479 0.365 0.19 0.722 1.61 0.789 3.3 0.432 0.371 0.244 0.6129 1.54 0.745 3.18 PRS_PLINK_0.001 FALSE 286 Coagulation defects Both 203 2026 4 hematopoietic darkorange1 2026, 203 507, 50 506, 50 506, 61 507, 42 -0.00783 0.121 0.948 0.02301 0.992 0.783 1.26 0.016 0.208 0.939 0.02746 1.02 0.675 1.53 0.187 0.199 0.347 0.4597 1.21 0.816 1.78 -0.162 0.216 0.452 0.3444 0.85 0.557 1.3 PRS_PLINK_0.001 FALSE 286.1 Congenital coagulation defects Both 120 1032 4 hematopoietic darkorange1 1032, 120 258, 25 258, 32 258, 41 258, 22 0.0115 0.103 0.911 0.04051 1.01 0.827 1.24 0.273 0.277 0.325 0.4877 1.31 0.763 2.26 0.494 0.265 0.0627 1.203 1.64 0.974 2.76 -0.11 0.298 0.712 0.1473 0.896 0.5 1.61 PRS_PLINK_0.001 FALSE 286.11 Von willebrand's disease Both 25 223 4 hematopoietic darkorange1 223, 25 56, 8 56, 7 55, 5 56, 5 -0.306 0.606 0.614 0.2121 0.736 0.224 2.42 0.00428 0.529 0.994 0.002815 1 0.356 2.83 -0.168 0.59 0.776 0.1103 0.845 0.266 2.69 -0.183 0.594 0.758 0.1202 0.833 0.26 2.67 PRS_PLINK_0.001 TRUE 286.12 Congenital deficiency of other clotting factors (including factor VII) Both 79 654 4 hematopoietic darkorange1 654, 79 164, 18 163, 18 163, 29 164, 14 0.0174 0.099 0.861 0.06522 1.02 0.838 1.24 0.0352 0.342 0.918 0.03708 1.04 0.529 2.03 0.47 0.314 0.134 0.8727 1.6 0.865 2.96 -0.182 0.362 0.615 0.211 0.834 0.41 1.69 PRS_PLINK_0.001 FALSE 286.13 Congenital factor VIII disorder Both 14 129 4 hematopoietic darkorange1 129, 14 33, 2 32, 5 32, 4 32, 3 0.0339 0.907 0.97 0.01313 1.03 0.175 6.12 0.724 0.846 0.392 0.4065 2.06 0.393 10.8 0.828 0.908 0.361 0.442 2.29 0.386 13.6 0.514 0.811 0.526 0.2787 1.67 0.341 8.19 PRS_PLINK_0.001 TRUE 286.5 Hemorrhagic disorder due to intrinsic circulating anticoagulants Both 12 179 4 hematopoietic darkorange1 179, 12 45, 1 45, 2 44, 7 45, 2 0.894 0.926 0.334 0.4759 2.44 0.398 15 0.25 0.882 0.776 0.1099 1.28 0.228 7.23 2.01 0.9 0.0254 1.595 7.48 1.28 43.7 0.284 0.864 0.742 0.1295 1.33 0.244 7.23 PRS_PLINK_0.001 TRUE 286.7 Other and unspecified coagulation defects Both 81 828 4 hematopoietic darkorange1 828, 81 207, 21 207, 16 207, 17 207, 27 0.111 0.402 0.782 0.1069 1.12 0.509 2.46 -0.355 0.339 0.295 0.5301 0.701 0.361 1.36 -0.211 0.33 0.522 0.2821 0.81 0.424 1.55 0.241 0.3 0.422 0.3747 1.27 0.707 2.29 PRS_PLINK_0.001 FALSE 287 Purpura and other hemorrhagic conditions Both 300 3520 4 hematopoietic darkorange1 3520, 300 880, 84 880, 71 880, 65 880, 80 0.0349 0.0492 0.479 0.3201 1.04 0.94 1.14 -0.159 0.167 0.34 0.4679 0.853 0.615 1.18 -0.244 0.17 0.152 0.8191 0.783 0.561 1.09 -0.0387 0.162 0.812 0.09071 0.962 0.7 1.32 PRS_PLINK_0.001 FALSE 287.1 Spontaneous ecchymoses Both 21 266 4 hematopoietic darkorange1 266, 21 67, 5 66, 3 66, 8 67, 5 0.0558 0.752 0.941 0.0265 1.06 0.242 4.62 -0.26 0.665 0.696 0.1576 0.771 0.21 2.84 0.35 0.565 0.536 0.2711 1.42 0.469 4.3 0.0624 0.6 0.917 0.03758 1.06 0.328 3.45 PRS_PLINK_0.001 TRUE 287.2 Allergic purpura Both 7 120 4 hematopoietic darkorange1 120, 7 30, 1 30, 2 30, 4 30, 0 -0.579 1.23 0.638 0.1951 0.56 0.0502 6.25 0.825 1.03 0.425 0.3719 2.28 0.301 17.3 0.936 0.896 0.296 0.5283 2.55 0.44 14.8 -0.243 1.11 0.826 0.08283 0.784 0.0897 6.86 PRS_PLINK_0.001 TRUE 287.3 Thrombocytopenia Both 282 3298 4 hematopoietic darkorange1 3298, 282 825, 79 824, 67 824, 59 825, 77 0.0414 0.0501 0.409 0.3884 1.04 0.945 1.15 -0.154 0.172 0.369 0.4331 0.857 0.612 1.2 -0.282 0.177 0.112 0.9527 0.754 0.533 1.07 -0.017 0.166 0.918 0.03692 0.983 0.709 1.36 PRS_PLINK_0.001 FALSE 287.31 Primary thrombocytopenia Both 87 883 4 hematopoietic darkorange1 883, 87 221, 24 221, 20 220, 19 221, 24 0.127 0.073 0.0823 1.085 1.14 0.984 1.31 -0.175 0.31 0.574 0.2413 0.84 0.457 1.54 -0.203 0.314 0.519 0.2849 0.817 0.441 1.51 0.0309 0.299 0.918 0.03731 1.03 0.574 1.85 PRS_PLINK_0.001 FALSE 287.32 Secondary thrombocytopenia Both 8 145 4 hematopoietic darkorange1 145, 8 37, 4 36, 1 36, 1 36, 2 -0.425 1 0.671 0.1732 0.654 0.0921 4.64 -1.1 0.851 0.195 0.7104 0.332 0.0625 1.76 -0.99 0.833 0.235 0.6292 0.372 0.0725 1.9 -0.506 0.737 0.492 0.3081 0.603 0.142 2.56 PRS_PLINK_0.001 TRUE 288 Diseases of white blood cells Both 667 7892 4 hematopoietic darkorange1 7892, 667 1973, 149 1973, 162 1973, 180 1973, 176 0.00774 0.0349 0.824 0.08393 1.01 0.941 1.08 0.0863 0.117 0.462 0.335 1.09 0.866 1.37 0.189 0.115 0.0997 1.001 1.21 0.965 1.51 0.161 0.115 0.162 0.7917 1.18 0.937 1.47 PRS_PLINK_0.001 FALSE 288.1 Decreased white blood cell count Both 571 6698 4 hematopoietic darkorange1 6698, 571 1675, 134 1674, 144 1674, 150 1675, 143 -0.0259 0.0507 0.61 0.2145 0.974 0.882 1.08 0.0736 0.124 0.554 0.2567 1.08 0.844 1.37 0.114 0.123 0.356 0.449 1.12 0.88 1.43 0.0639 0.125 0.608 0.216 1.07 0.835 1.36 PRS_PLINK_0.001 FALSE 288.11 Neutropenia Both 572 6725 4 hematopoietic darkorange1 6725, 572 1682, 134 1681, 144 1681, 150 1681, 144 -0.0253 0.0505 0.617 0.2097 0.975 0.883 1.08 0.0736 0.124 0.554 0.2566 1.08 0.844 1.37 0.113 0.123 0.36 0.4439 1.12 0.879 1.43 0.0726 0.124 0.559 0.2523 1.08 0.843 1.37 PRS_PLINK_0.001 FALSE 288.3 Eosinophilia Both 18 146 4 hematopoietic darkorange1 146, 18 37, 2 36, 5 36, 7 37, 4 0.171 0.12 0.154 0.8117 1.19 0.938 1.5 0.669 0.77 0.385 0.4142 1.95 0.431 8.83 1.29 0.749 0.0859 1.066 3.62 0.834 15.7 0.636 0.775 0.412 0.3854 1.89 0.413 8.64 PRS_PLINK_0.001 TRUE 289 Other diseases of blood and blood-forming organs Both 173 1839 4 hematopoietic darkorange1 1839, 173 460, 34 460, 46 459, 48 460, 45 0.0432 0.0747 0.563 0.2493 1.04 0.902 1.21 0.307 0.232 0.187 0.7285 1.36 0.862 2.14 0.365 0.23 0.113 0.9483 1.44 0.918 2.26 0.26 0.233 0.265 0.5773 1.3 0.821 2.05 PRS_PLINK_0.001 FALSE 289.3 Personal history of diseases of blood and blood-forming organs Both 55 628 4 hematopoietic darkorange1 628, 55 157, 8 157, 15 157, 13 157, 19 0.948 0.467 0.0422 1.374 2.58 1.03 6.44 0.518 0.429 0.227 0.6432 1.68 0.724 3.89 0.519 0.44 0.238 0.623 1.68 0.71 3.98 0.812 0.414 0.05 1.301 2.25 1 5.08 PRS_PLINK_0.001 FALSE 289.4 Lymphadenitis Both 448 5670 4 hematopoietic darkorange1 5670, 448 1418, 122 1417, 101 1417, 108 1418, 117 -0.0575 0.0744 0.439 0.357 0.944 0.816 1.09 -0.173 0.139 0.214 0.6689 0.841 0.641 1.11 -0.107 0.137 0.436 0.3606 0.899 0.688 1.18 -0.0443 0.134 0.741 0.1301 0.957 0.736 1.24 PRS_PLINK_0.001 FALSE 289.5 Diseases of spleen Both 68 1098 4 hematopoietic darkorange1 1098, 68 275, 21 274, 16 274, 13 275, 18 0.0258 0.0749 0.73 0.1365 1.03 0.886 1.19 -0.239 0.332 0.47 0.3275 0.787 0.411 1.51 -0.45 0.35 0.198 0.7036 0.638 0.321 1.26 -0.18 0.321 0.575 0.2405 0.835 0.445 1.57 PRS_PLINK_0.001 FALSE 289.8 Polycythemia, secondary Both 42 607 4 hematopoietic darkorange1 607, 42 152, 10 152, 10 151, 11 152, 11 0.0428 0.0904 0.636 0.1966 1.04 0.874 1.25 0.0657 0.446 0.883 0.05411 1.07 0.446 2.56 -0.0989 0.453 0.827 0.08244 0.906 0.373 2.2 0.136 0.43 0.752 0.1238 1.15 0.493 2.66 PRS_PLINK_0.001 TRUE 289.9 Abnormality of red blood cells Both 21 189 4 hematopoietic darkorange1 189, 21 48, 7 47, 5 47, 7 47, 2 -0.928 0.847 0.273 0.5632 0.396 0.0752 2.08 -0.177 0.6 0.768 0.1145 0.838 0.258 2.72 0.102 0.55 0.853 0.06882 1.11 0.376 3.26 -0.995 0.765 0.194 0.7133 0.37 0.0825 1.66 PRS_PLINK_0.001 TRUE 290 Delirium dementia and amnestic and other cognitive disorders Both 209 3756 5 mental disorders magenta 3756, 209 938, 51 939, 59 939, 43 939, 56 0.025 0.0758 0.742 0.1297 1.03 0.884 1.19 0.129 0.194 0.506 0.2956 1.14 0.777 1.67 -0.161 0.208 0.441 0.356 0.851 0.566 1.28 0.0723 0.197 0.713 0.1468 1.07 0.731 1.58 PRS_PLINK_0.001 FALSE 290.1 Dementias Both 102 1901 5 mental disorders magenta 1901, 102 475, 24 475, 34 475, 20 475, 24 0.0223 0.086 0.795 0.09939 1.02 0.864 1.21 0.345 0.268 0.199 0.701 1.41 0.834 2.39 -0.138 0.299 0.643 0.1915 0.871 0.484 1.56 -0.0404 0.288 0.888 0.05137 0.96 0.546 1.69 PRS_PLINK_0.001 FALSE 290.11 Alzheimer's disease Both 44 823 5 mental disorders magenta 823, 44 205, 8 206, 17 205, 9 206, 10 0.452 0.486 0.353 0.4522 1.57 0.606 4.08 0.746 0.416 0.0731 1.136 2.11 0.932 4.77 0.155 0.455 0.734 0.1344 1.17 0.479 2.84 0.0881 0.454 0.846 0.07263 1.09 0.449 2.66 PRS_PLINK_0.001 TRUE 290.16 Vascular dementia Both 23 364 5 mental disorders magenta 364, 23 91, 6 91, 6 91, 4 91, 7 0.0765 0.125 0.541 0.2666 1.08 0.844 1.38 -0.174 0.559 0.755 0.1219 0.84 0.281 2.51 -0.308 0.577 0.594 0.2265 0.735 0.238 2.28 -0.104 0.568 0.855 0.06828 0.901 0.296 2.74 PRS_PLINK_0.001 TRUE 290.2 Delirium due to conditions classified elsewhere Both 77 1288 5 mental disorders magenta 1288, 77 322, 22 322, 23 322, 11 322, 21 0.0991 0.121 0.412 0.3846 1.1 0.871 1.4 0.0676 0.301 0.822 0.08517 1.07 0.594 1.93 -0.659 0.359 0.0668 1.175 0.517 0.256 1.05 -0.0203 0.307 0.947 0.02352 0.98 0.537 1.79 PRS_PLINK_0.001 FALSE 290.3 Other persistent mental disorders due to conditions classified elsewhere Both 5 134 5 mental disorders magenta 134, 5 34, 1 33, 4 33, 0 34, 0 -1.21 1.57 0.442 0.3547 0.298 0.0136 6.52 1.21 1.03 0.24 0.6197 3.34 0.447 24.9 0.361 1.3 0.781 0.1074 1.44 0.113 18.3 -0.0894 1.22 0.942 0.02613 0.914 0.0835 10 PRS_PLINK_0.001 TRUE 291 Other specified nonpsychotic and/or transient mental disorders Both 126 1788 5 mental disorders magenta 1788, 126 447, 32 447, 26 447, 37 447, 31 0.0482 0.0418 0.249 0.6041 1.05 0.967 1.14 -0.207 0.265 0.436 0.3604 0.813 0.483 1.37 0.126 0.245 0.607 0.2171 1.13 0.702 1.83 -0.0234 0.255 0.927 0.03298 0.977 0.593 1.61 PRS_PLINK_0.001 FALSE 291.1 Transient mental disorders due to conditions classified elsewhere Both 19 279 5 mental disorders magenta 279, 19 70, 5 70, 2 69, 7 70, 5 -0.948 0.711 0.182 0.739 0.387 0.0962 1.56 0.29 0.554 0.6 0.2216 1.34 0.451 3.96 -0.119 0.597 0.843 0.07439 0.888 0.276 2.86 PRS_PLINK_0.001 TRUE 291.4 Specific nonpsychotic mental disorders due to brain damage Both 35 575 5 mental disorders magenta 575, 35 144, 10 144, 8 143, 7 144, 10 0.0535 0.0962 0.578 0.2379 1.05 0.874 1.27 -0.17 0.457 0.709 0.1493 0.843 0.345 2.06 -0.303 0.475 0.524 0.2805 0.739 0.291 1.88 -0.013 0.439 0.976 0.01034 0.987 0.417 2.33 PRS_PLINK_0.001 TRUE 291.8 Alteration of consciousness Both 72 936 5 mental disorders magenta 936, 72 234, 19 234, 14 234, 23 234, 16 0.129 0.0734 0.08 1.097 1.14 0.985 1.31 -0.286 0.35 0.414 0.383 0.751 0.379 1.49 0.14 0.314 0.655 0.1836 1.15 0.622 2.13 -0.171 0.338 0.614 0.2119 0.843 0.435 1.64 PRS_PLINK_0.001 FALSE 292 Neurological disorders Both 663 9454 5 mental disorders magenta 9454, 663 2364, 161 2363, 165 2363, 158 2364, 179 -0.0232 0.0561 0.68 0.1675 0.977 0.875 1.09 0.022 0.114 0.847 0.07212 1.02 0.817 1.28 -0.0192 0.115 0.867 0.06176 0.981 0.783 1.23 0.106 0.112 0.346 0.4606 1.11 0.892 1.38 PRS_PLINK_0.001 FALSE 292.1 Aphasia/speech disturbance Both 207 3146 5 mental disorders magenta 3146, 207 787, 45 786, 57 786, 42 787, 63 0.0265 0.0556 0.634 0.1982 1.03 0.921 1.15 0.22 0.203 0.279 0.5549 1.25 0.837 1.85 -0.07 0.217 0.747 0.1266 0.932 0.609 1.43 0.322 0.199 0.105 0.9783 1.38 0.935 2.04 PRS_PLINK_0.001 FALSE 292.2 Mild cognitive impairment Both 22 385 5 mental disorders magenta 385, 22 97, 8 96, 3 96, 3 96, 8 0.104 0.12 0.384 0.4162 1.11 0.878 1.4 -0.805 0.606 0.184 0.7352 0.447 0.136 1.47 -0.705 0.612 0.25 0.6025 0.494 0.149 1.64 0.0543 0.492 0.912 0.03994 1.06 0.403 2.77 PRS_PLINK_0.001 TRUE 292.3 Memory loss Both 123 1483 5 mental disorders magenta 1483, 123 371, 36 371, 28 370, 41 371, 18 -0.56 0.315 0.075 1.125 0.571 0.308 1.06 -0.228 0.257 0.375 0.4259 0.796 0.481 1.32 0.109 0.237 0.645 0.1907 1.12 0.701 1.77 -0.702 0.29 0.0156 1.807 0.495 0.28 0.875 PRS_PLINK_0.001 FALSE 292.4 Altered mental status Both 300 4354 5 mental disorders magenta 4354, 300 1089, 74 1088, 67 1088, 74 1089, 85 0.0116 0.0727 0.874 0.0587 1.01 0.877 1.17 -0.0883 0.172 0.609 0.2157 0.915 0.653 1.28 0.00458 0.169 0.978 0.009515 1 0.722 1.4 0.14 0.163 0.393 0.406 1.15 0.835 1.58 PRS_PLINK_0.001 FALSE 292.6 Hallucinations Both 42 590 5 mental disorders magenta 590, 42 148, 9 147, 11 147, 10 148, 12 0.051 0.12 0.671 0.1731 1.05 0.831 1.33 0.12 0.439 0.785 0.1052 1.13 0.477 2.67 -0.0702 0.452 0.877 0.05713 0.932 0.384 2.26 0.28 0.442 0.526 0.2789 1.32 0.557 3.14 PRS_PLINK_0.001 TRUE 293 Symptoms involving head and neck Both 398 4493 5 mental disorders magenta 4493, 398 1124, 78 1123, 107 1123, 115 1123, 98 0.0632 0.0456 0.165 0.7818 1.07 0.974 1.16 0.315 0.154 0.0404 1.394 1.37 1.01 1.85 0.39 0.151 0.0101 1.996 1.48 1.1 1.99 0.231 0.156 0.14 0.8536 1.26 0.927 1.71 PRS_PLINK_0.001 FALSE 293.1 Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS] Both 143 1938 5 mental disorders magenta 1938, 143 485, 33 484, 38 484, 35 485, 37 0.0182 0.0674 0.787 0.104 1.02 0.892 1.16 0.17 0.242 0.483 0.3164 1.19 0.737 1.91 0.107 0.248 0.667 0.1762 1.11 0.684 1.81 0.166 0.245 0.499 0.3018 1.18 0.73 1.91 PRS_PLINK_0.001 FALSE 295 Schizophrenia and other psychotic disorders Both 93 1866 5 mental disorders magenta 1866, 93 467, 25 466, 24 466, 22 467, 22 0.0242 0.101 0.81 0.09158 1.02 0.841 1.25 -0.0134 0.285 0.962 0.01663 0.987 0.564 1.73 -0.119 0.292 0.684 0.1648 0.888 0.501 1.57 -0.145 0.291 0.618 0.2093 0.865 0.489 1.53 PRS_PLINK_0.001 FALSE 295.1 Schizophrenia Both 65 1282 5 mental disorders magenta 1282, 65 321, 16 320, 16 320, 17 321, 16 0.0152 0.0901 0.866 0.06267 1.02 0.851 1.21 0.0414 0.348 0.905 0.04317 1.04 0.527 2.06 0.109 0.342 0.751 0.1245 1.11 0.57 2.18 -0.0381 0.347 0.913 0.03976 0.963 0.488 1.9 PRS_PLINK_0.001 FALSE 295.2 Paranoid disorders Both 21 406 5 mental disorders magenta 406, 21 102, 7 101, 7 101, 4 102, 3 -1.02 0.717 0.154 0.8111 0.361 0.0885 1.47 -0.036 0.538 0.947 0.0238 0.965 0.336 2.77 -0.53 0.601 0.378 0.4227 0.588 0.181 1.91 -0.59 0.611 0.334 0.4761 0.554 0.167 1.84 PRS_PLINK_0.001 TRUE 295.3 Psychosis Both 14 362 5 mental disorders magenta 362, 14 91, 3 90, 1 90, 6 91, 4 0.838 0.875 0.338 0.4707 2.31 0.416 12.8 -0.595 0.824 0.47 0.3281 0.551 0.11 2.77 0.486 0.632 0.442 0.3543 1.63 0.471 5.61 0.4 0.703 0.57 0.2442 1.49 0.376 5.92 PRS_PLINK_0.001 TRUE 296 Mood disorders Both 1913 27363 5 mental disorders magenta 27363, 1913 6841, 479 6841, 477 6840, 453 6841, 504 -0.0417 0.0308 0.176 0.7544 0.959 0.903 1.02 -0.00354 0.0668 0.958 0.01876 0.996 0.874 1.14 -0.0543 0.0676 0.422 0.3747 0.947 0.83 1.08 0.0505 0.066 0.444 0.3531 1.05 0.924 1.2 PRS_PLINK_0.001 FALSE 296.1 Bipolar Both 150 2311 5 mental disorders magenta 2311, 150 578, 34 578, 40 577, 41 578, 35 0.00978 0.0654 0.881 0.05497 1.01 0.888 1.15 0.165 0.236 0.484 0.3151 1.18 0.743 1.87 0.203 0.235 0.389 0.4106 1.22 0.773 1.94 0.0428 0.243 0.86 0.06534 1.04 0.648 1.68 PRS_PLINK_0.001 FALSE 296.2 Depression Both 1823 26023 5 mental disorders magenta 26023, 1823 6506, 465 6506, 449 6505, 426 6506, 483 -0.0433 0.0319 0.174 0.759 0.958 0.9 1.02 -0.0345 0.0684 0.614 0.2118 0.966 0.845 1.1 -0.0863 0.0692 0.213 0.6723 0.917 0.801 1.05 0.0371 0.0672 0.581 0.236 1.04 0.91 1.18 PRS_PLINK_0.001 FALSE 296.22 Major depressive disorder Both 50 789 5 mental disorders magenta 789, 50 198, 15 197, 9 197, 9 197, 17 0.0358 0.0634 0.572 0.2424 1.04 0.915 1.17 -0.511 0.407 0.209 0.6791 0.6 0.27 1.33 -0.468 0.407 0.251 0.6 0.627 0.282 1.39 0.111 0.357 0.755 0.1222 1.12 0.556 2.25 PRS_PLINK_0.001 TRUE 297.2 Suicide or self-inflicted injury Both 31 615 5 mental disorders magenta 615, 31 154, 5 154, 4 153, 10 154, 12 1.38 0.617 0.0249 1.604 3.99 1.19 13.4 -0.29 0.583 0.618 0.2087 0.748 0.239 2.34 0.686 0.503 0.173 0.763 1.98 0.741 5.32 0.774 0.498 0.12 0.9215 2.17 0.818 5.76 PRS_PLINK_0.001 TRUE 300 Anxiety disorders Both 1055 15067 5 mental disorders magenta 15067, 1055 3766, 259 3767, 244 3766, 263 3767, 289 -0.00126 0.0303 0.967 0.01471 0.999 0.941 1.06 -0.0635 0.0919 0.489 0.3104 0.938 0.784 1.12 0.0165 0.0903 0.855 0.06812 1.02 0.852 1.21 0.106 0.0884 0.231 0.6364 1.11 0.935 1.32 PRS_PLINK_0.001 FALSE 300.1 Anxiety disorder Both 971 13929 5 mental disorders magenta 13929, 971 3482, 242 3482, 216 3482, 247 3482, 266 0.00532 0.0306 0.862 0.06453 1.01 0.947 1.07 -0.117 0.0963 0.223 0.6515 0.889 0.736 1.07 0.0227 0.0933 0.807 0.09289 1.02 0.852 1.23 0.0941 0.0918 0.305 0.5151 1.1 0.918 1.32 PRS_PLINK_0.001 FALSE 300.11 Generalized anxiety disorder Both 20 342 5 mental disorders magenta 342, 20 86, 7 85, 2 85, 6 86, 5 -0.497 0.762 0.514 0.2889 0.608 0.137 2.71 -1.02 0.677 0.131 0.8836 0.359 0.0952 1.36 -0.0438 0.549 0.936 0.02856 0.957 0.326 2.81 -0.252 0.549 0.647 0.1894 0.777 0.265 2.28 PRS_PLINK_0.001 TRUE 300.12 Agorophobia, social phobia, and panic disorder Both 107 1529 5 mental disorders magenta 1529, 107 382, 25 382, 17 382, 32 382, 33 0.0265 0.0767 0.73 0.1367 1.03 0.883 1.19 -0.358 0.311 0.25 0.6018 0.699 0.38 1.29 0.225 0.27 0.404 0.3933 1.25 0.738 2.13 0.246 0.269 0.362 0.4412 1.28 0.754 2.17 PRS_PLINK_0.001 FALSE 300.13 Phobia Both 93 1122 5 mental disorders magenta 1122, 93 281, 16 280, 26 280, 31 281, 20 0.0568 0.113 0.615 0.2114 1.06 0.849 1.32 0.42 0.319 0.188 0.7262 1.52 0.815 2.84 0.646 0.309 0.0362 1.442 1.91 1.04 3.49 0.272 0.333 0.415 0.3823 1.31 0.683 2.52 PRS_PLINK_0.001 FALSE 300.3 Obsessive-compulsive disorders Both 18 301 5 mental disorders magenta 301, 18 76, 4 75, 3 75, 6 75, 5 0.14 0.104 0.178 0.7507 1.15 0.939 1.41 -0.381 0.712 0.593 0.2272 0.683 0.169 2.76 0.684 0.622 0.272 0.566 1.98 0.585 6.71 0.196 0.634 0.757 0.1207 1.22 0.351 4.21 PRS_PLINK_0.001 TRUE 300.4 Dysthymic disorder Both 9 141 5 mental disorders magenta 141, 9 36, 3 35, 3 35, 2 35, 1 -1.15 1.06 0.276 0.5596 0.315 0.0395 2.51 -0.17 0.744 0.819 0.08664 0.844 0.196 3.63 -0.321 0.806 0.69 0.161 0.725 0.15 3.52 -0.616 0.838 0.462 0.3351 0.54 0.105 2.79 PRS_PLINK_0.001 TRUE 300.8 Acute reaction to stress Both 18 282 5 mental disorders magenta 282, 18 71, 3 70, 6 70, 3 71, 6 0.392 0.785 0.617 0.2095 1.48 0.318 6.89 0.703 0.638 0.27 0.5686 2.02 0.579 7.05 -0.0658 0.757 0.931 0.03119 0.936 0.212 4.13 0.625 0.629 0.32 0.4945 1.87 0.545 6.41 PRS_PLINK_0.001 TRUE 300.9 Posttraumatic stress disorder Both 18 250 5 mental disorders magenta 250, 18 63, 2 62, 4 62, 6 63, 6 0.729 0.772 0.345 0.4618 2.07 0.456 9.41 1.19 0.905 0.19 0.7214 3.27 0.556 19.3 0.977 0.7 0.163 0.789 2.66 0.674 10.5 0.901 0.702 0.199 0.7002 2.46 0.622 9.74 PRS_PLINK_0.001 TRUE 301 Personality disorders Both 35 769 5 mental disorders magenta 769, 35 193, 10 192, 13 192, 5 192, 7 -0.411 0.569 0.471 0.3273 0.663 0.217 2.02 0.238 0.412 0.563 0.2494 1.27 0.566 2.84 -0.741 0.509 0.145 0.8383 0.477 0.176 1.29 -0.262 0.463 0.572 0.2427 0.77 0.31 1.91 PRS_PLINK_0.001 TRUE 301.2 Antisocial/borderline personality disorder Both 12 274 5 mental disorders magenta 274, 12 69, 3 68, 4 68, 2 69, 3 -0.00049 0.974 1 0.0001744 1 0.148 6.74 0.393 0.719 0.585 0.2331 1.48 0.362 6.06 -0.814 0.822 0.322 0.4922 0.443 0.0884 2.22 0.00189 0.715 0.998 0.0009154 1 0.247 4.07 PRS_PLINK_0.001 TRUE 302 Sexual and gender identity disorders Both 37 598 5 mental disorders magenta 598, 37 150, 8 149, 6 149, 10 150, 13 0.0921 0.113 0.415 0.3815 1.1 0.878 1.37 -0.421 0.513 0.412 0.3854 0.656 0.24 1.79 0.225 0.461 0.625 0.204 1.25 0.507 3.09 0.45 0.436 0.302 0.5198 1.57 0.667 3.68 PRS_PLINK_0.001 TRUE 303 Psychogenic and somatoform disorders Both 76 1087 5 mental disorders magenta 1087, 76 272, 21 272, 9 271, 28 272, 18 0.0639 0.0932 0.493 0.3072 1.07 0.888 1.28 -0.879 0.392 0.025 1.602 0.415 0.193 0.896 0.323 0.298 0.278 0.5553 1.38 0.77 2.48 -0.146 0.323 0.65 0.1869 0.864 0.459 1.63 PRS_PLINK_0.001 FALSE 303.3 Psychogenic disorder Both 59 802 5 mental disorders magenta 802, 59 201, 16 200, 11 200, 23 201, 9 0.0438 0.104 0.673 0.1722 1.04 0.853 1.28 -0.416 0.392 0.288 0.5402 0.659 0.306 1.42 0.337 0.336 0.315 0.5014 1.4 0.725 2.71 -0.575 0.404 0.154 0.8114 0.563 0.255 1.24 PRS_PLINK_0.001 FALSE 303.4 Somatoform disorder Both 18 265 5 mental disorders magenta 265, 18 67, 5 66, 0 66, 4 66, 9 1.31 0.835 0.116 0.9355 3.72 0.723 19.1 -2.6 1.31 0.0472 1.326 0.0743 0.0057 0.968 -0.118 0.645 0.855 0.06793 0.889 0.251 3.15 0.672 0.557 0.228 0.6426 1.96 0.657 5.84 PRS_PLINK_0.001 TRUE 304 Adjustment reaction Both 48 676 5 mental disorders magenta 676, 48 169, 10 169, 8 169, 12 169, 18 0.835 0.472 0.0766 1.116 2.3 0.915 5.81 -0.0905 0.469 0.847 0.0721 0.913 0.364 2.29 0.163 0.428 0.704 0.1523 1.18 0.508 2.72 0.621 0.394 0.115 0.9401 1.86 0.86 4.03 PRS_PLINK_0.001 TRUE 305.2 Eating disorder Both 12 218 5 mental disorders magenta 218, 12 55, 6 54, 1 54, 2 55, 3 -1.14 0.931 0.219 0.6589 0.319 0.0514 1.98 -1.47 0.854 0.0855 1.068 0.23 0.0432 1.23 -1.4 0.828 0.0913 1.04 0.247 0.0487 1.25 -0.557 0.668 0.405 0.393 0.573 0.155 2.12 PRS_PLINK_0.001 TRUE 306 Other mental disorder Both 4870 49783 5 mental disorders magenta 49783, 4870 12445, 1211 12446, 1254 12445, 1200 12446, 1205 -0.0144 0.0162 0.375 0.4255 0.986 0.955 1.02 0.0373 0.0423 0.378 0.4219 1.04 0.955 1.13 -0.00856 0.0427 0.841 0.07503 0.991 0.912 1.08 -0.00329 0.0427 0.939 0.02755 0.997 0.917 1.08 PRS_PLINK_0.001 FALSE 306.9 Tension headache Both 48 723 5 mental disorders magenta 723, 48 181, 9 181, 15 180, 9 181, 15 0.0422 0.114 0.711 0.148 1.04 0.834 1.3 0.372 0.416 0.371 0.4303 1.45 0.642 3.28 0.0479 0.45 0.915 0.03846 1.05 0.434 2.54 0.375 0.419 0.37 0.4316 1.46 0.641 3.31 PRS_PLINK_0.001 TRUE 313 Pervasive developmental disorders Both 13 172 5 mental disorders magenta 172, 13 43, 4 43, 1 43, 1 43, 7 0.0427 0.125 0.733 0.1347 1.04 0.816 1.33 -1.02 0.861 0.235 0.6291 0.36 0.0665 1.94 -0.803 0.835 0.336 0.4731 0.448 0.0873 2.3 0.454 0.647 0.483 0.3165 1.57 0.443 5.59 PRS_PLINK_0.001 TRUE 313.3 Autism Both 9 125 5 mental disorders magenta 125, 9 32, 4 31, 1 31, 1 31, 3 -0.922 0.871 0.29 0.5375 0.398 0.0721 2.19 -0.534 0.854 0.532 0.2742 0.586 0.11 3.13 -0.797 0.864 0.356 0.4486 0.451 0.0829 2.45 PRS_PLINK_0.001 TRUE 315 Develomental delays and disorders Both 35 780 5 mental disorders magenta 780, 35 195, 8 195, 10 195, 4 195, 13 0.11 0.0934 0.239 0.6225 1.12 0.93 1.34 0.128 0.461 0.78 0.1076 1.14 0.461 2.81 -0.658 0.545 0.228 0.6429 0.518 0.178 1.51 0.488 0.431 0.257 0.5898 1.63 0.7 3.79 PRS_PLINK_0.001 TRUE 315.1 Learning disorder Both 8 363 5 mental disorders magenta 363, 8 91, 1 91, 1 90, 3 91, 3 0.185 0.123 0.132 0.8783 1.2 0.946 1.53 0.525 0.972 0.589 0.2299 1.69 0.252 11.4 0.467 0.885 0.597 0.2237 1.6 0.282 9.04 1.37 0.95 0.149 0.8267 3.94 0.612 25.3 PRS_PLINK_0.001 TRUE 315.2 Speech and language disorder Both 17 180 5 mental disorders magenta 180, 17 45, 5 45, 3 45, 3 45, 6 0.396 0.772 0.608 0.2164 1.49 0.327 6.75 -0.41 0.721 0.569 0.2445 0.663 0.161 2.73 -0.496 0.806 0.539 0.2688 0.609 0.126 2.96 0.379 0.643 0.555 0.2555 1.46 0.414 5.15 PRS_PLINK_0.001 TRUE 316 Substance addiction and disorders Both 636 11573 5 mental disorders magenta 11573, 636 2894, 169 2893, 153 2893, 148 2893, 166 0.0296 0.0333 0.375 0.4257 1.03 0.965 1.1 -0.0997 0.114 0.382 0.4174 0.905 0.724 1.13 -0.135 0.115 0.24 0.6193 0.874 0.697 1.09 -0.022 0.112 0.844 0.07353 0.978 0.786 1.22 PRS_PLINK_0.001 FALSE 316.1 Polyneuropathy due to drugs Both 9 136 5 mental disorders magenta 136, 9 34, 2 34, 1 34, 1 34, 5 -0.424 1.06 0.69 0.1614 0.654 0.0816 5.25 -0.0215 0.973 0.982 0.007711 0.979 0.145 6.59 1 0.845 0.235 0.629 2.73 0.521 14.3 PRS_PLINK_0.001 TRUE 317 Alcohol-related disorders Both 1936 27811 5 mental disorders magenta 27811, 1936 6953, 483 6953, 504 6952, 479 6953, 470 0.014 0.0207 0.499 0.3016 1.01 0.974 1.06 0.0453 0.0658 0.491 0.3091 1.05 0.92 1.19 -0.0058 0.0666 0.931 0.03122 0.994 0.873 1.13 -0.0284 0.0669 0.672 0.1729 0.972 0.853 1.11 PRS_PLINK_0.001 FALSE 317.1 Alcoholism Both 1427 19348 5 mental disorders magenta 19348, 1427 4837, 356 4837, 373 4837, 355 4837, 343 0.0145 0.0255 0.57 0.2441 1.01 0.965 1.07 0.0492 0.0767 0.521 0.2832 1.05 0.904 1.22 0.00215 0.0776 0.978 0.009719 1 0.861 1.17 -0.0385 0.0782 0.622 0.206 0.962 0.825 1.12 PRS_PLINK_0.001 FALSE 317.11 Alcoholic liver damage Both 88 1821 5 mental disorders magenta 1821, 88 456, 29 455, 22 455, 18 455, 19 0.0526 0.11 0.633 0.1986 1.05 0.849 1.31 -0.289 0.282 0.305 0.5152 0.749 0.431 1.3 -0.484 0.298 0.105 0.979 0.617 0.344 1.11 -0.398 0.294 0.176 0.7534 0.672 0.377 1.2 PRS_PLINK_0.001 FALSE 318 Tobacco use disorder Both 2658 40767 5 mental disorders magenta 40767, 2658 10192, 653 10192, 688 10191, 680 10192, 637 0.0194 0.0163 0.235 0.6291 1.02 0.987 1.05 0.0492 0.0564 0.382 0.4175 1.05 0.941 1.17 0.037 0.0565 0.513 0.29 1.04 0.929 1.16 -0.0271 0.0574 0.637 0.1958 0.973 0.87 1.09 PRS_PLINK_0.001 FALSE 320 Meningitis Both 81 956 6 neurological darkblue 956, 81 239, 14 239, 23 239, 20 239, 24 0.0341 0.0797 0.669 0.1745 1.03 0.885 1.21 0.49 0.338 0.147 0.8318 1.63 0.841 3.17 0.324 0.345 0.347 0.4593 1.38 0.704 2.72 0.542 0.336 0.107 0.9716 1.72 0.89 3.32 PRS_PLINK_0.001 FALSE 323 Encephalitis Both 68 786 6 neurological darkblue 786, 68 197, 19 196, 23 196, 16 197, 10 -1.13 0.393 0.00397 2.402 0.322 0.149 0.696 0.21 0.319 0.51 0.2924 1.23 0.661 2.3 -0.197 0.345 0.568 0.246 0.821 0.417 1.61 -0.595 0.386 0.123 0.9089 0.552 0.259 1.18 PRS_PLINK_0.001 FALSE 323.2 Acute (transverse) myelitis Both 18 171 6 neurological darkblue 171, 18 43, 3 43, 5 42, 6 43, 4 -0.0112 0.723 0.988 0.005408 0.989 0.24 4.08 0.413 0.7 0.555 0.2554 1.51 0.383 5.95 0.714 0.708 0.313 0.5044 2.04 0.51 8.19 0.459 0.876 0.6 0.2217 1.58 0.284 8.81 PRS_PLINK_0.001 TRUE 324 Other CNS infection and poliomyelitis Both 54 598 6 neurological darkblue 598, 54 150, 14 149, 13 149, 17 150, 10 0.0108 0.0895 0.904 0.04375 1.01 0.848 1.2 -0.0717 0.385 0.852 0.06937 0.931 0.437 1.98 0.181 0.371 0.626 0.2036 1.2 0.579 2.48 -0.367 0.412 0.372 0.4295 0.693 0.309 1.55 PRS_PLINK_0.001 FALSE 327 Sleep disorders Both 238 2512 6 neurological darkblue 2512, 238 628, 57 628, 71 628, 54 628, 56 -0.0239 0.0779 0.759 0.1198 0.976 0.838 1.14 0.226 0.185 0.222 0.6531 1.25 0.872 1.8 -0.0645 0.196 0.742 0.1294 0.938 0.638 1.38 -0.0233 0.195 0.905 0.04358 0.977 0.667 1.43 PRS_PLINK_0.001 FALSE 327.3 Sleep apnea Both 798 9617 6 neurological darkblue 9617, 798 2405, 189 2404, 204 2404, 210 2404, 195 -0.000536 0.0391 0.989 0.004772 0.999 0.926 1.08 0.0731 0.105 0.486 0.3137 1.08 0.876 1.32 0.101 0.104 0.331 0.4799 1.11 0.902 1.36 0.0289 0.106 0.785 0.1052 1.03 0.837 1.27 PRS_PLINK_0.001 FALSE 327.4 Insomnia Both 34 365 6 neurological darkblue 365, 34 92, 8 91, 10 91, 10 91, 6 -0.612 0.561 0.275 0.5601 0.542 0.181 1.63 0.296 0.481 0.539 0.2687 1.34 0.523 3.45 0.138 0.476 0.771 0.1128 1.15 0.452 2.92 -0.373 0.54 0.49 0.3101 0.689 0.239 1.98 PRS_PLINK_0.001 TRUE 327.41 Organic or persistent insomnia Both 25 306 6 neurological darkblue 306, 25 77, 5 76, 8 76, 7 77, 5 -0.512 0.641 0.424 0.3723 0.599 0.171 2.1 0.301 0.544 0.58 0.2363 1.35 0.465 3.92 0.212 0.567 0.708 0.1502 1.24 0.407 3.75 -0.135 0.608 0.825 0.08369 0.874 0.265 2.88 PRS_PLINK_0.001 TRUE 331 Other cerebral degenerations Both 154 2352 6 neurological darkblue 2352, 154 588, 43 588, 50 588, 31 588, 30 -0.49 0.281 0.081 1.091 0.613 0.353 1.06 0.146 0.213 0.492 0.3079 1.16 0.763 1.76 -0.296 0.239 0.215 0.668 0.744 0.466 1.19 -0.339 0.24 0.157 0.8035 0.712 0.445 1.14 PRS_PLINK_0.001 FALSE 331.1 Hydrocephalus Both 80 1039 6 neurological darkblue 1039, 80 260, 24 260, 25 259, 13 260, 18 -0.432 0.401 0.281 0.552 0.649 0.296 1.42 0.0477 0.296 0.872 0.05951 1.05 0.587 1.87 -0.687 0.346 0.0468 1.329 0.503 0.255 0.99 -0.276 0.315 0.382 0.4183 0.759 0.409 1.41 PRS_PLINK_0.001 FALSE 331.9 Cerebral degeneration, unspecified Both 55 909 6 neurological darkblue 909, 55 228, 13 227, 20 227, 11 227, 11 -0.464 0.447 0.299 0.5248 0.628 0.262 1.51 0.453 0.355 0.202 0.6948 1.57 0.784 3.16 -0.15 0.398 0.706 0.1509 0.861 0.394 1.88 -0.193 0.397 0.627 0.2028 0.825 0.379 1.79 PRS_PLINK_0.001 FALSE 332 Parkinson's disease Both 175 2300 6 neurological darkblue 2300, 175 575, 43 575, 46 575, 42 575, 44 -0.0324 0.0795 0.684 0.1652 0.968 0.828 1.13 0.112 0.219 0.608 0.2162 1.12 0.729 1.72 -0.00321 0.223 0.989 0.00502 0.997 0.644 1.54 0.00222 0.22 0.992 0.003508 1 0.651 1.54 PRS_PLINK_0.001 FALSE 333 Extrapyramidal disease and abnormal movement disorders Both 148 1930 6 neurological darkblue 1930, 148 483, 30 482, 41 482, 41 483, 36 0.0234 0.071 0.742 0.1299 1.02 0.891 1.18 0.319 0.243 0.19 0.7208 1.38 0.854 2.22 0.309 0.243 0.205 0.6888 1.36 0.845 2.19 0.146 0.251 0.56 0.2516 1.16 0.707 1.9 PRS_PLINK_0.001 FALSE 333.1 Essential tremor Both 34 438 6 neurological darkblue 438, 34 110, 8 109, 7 109, 10 110, 9 0.0542 0.0995 0.586 0.2321 1.06 0.869 1.28 -0.141 0.497 0.777 0.1098 0.868 0.328 2.3 0.309 0.471 0.512 0.2911 1.36 0.542 3.43 -0.0442 0.488 0.928 0.03258 0.957 0.368 2.49 PRS_PLINK_0.001 TRUE 333.2 Myoclonus Both 10 219 6 neurological darkblue 219, 10 55, 1 55, 3 54, 3 55, 3 1.14 1.15 0.32 0.4945 3.13 0.33 29.7 1.3 1.01 0.198 0.7033 3.67 0.507 26.5 0.649 0.885 0.463 0.3343 1.91 0.338 10.8 0.88 0.844 0.297 0.5275 2.41 0.461 12.6 PRS_PLINK_0.001 TRUE 333.4 Torsion dystonia Both 49 524 6 neurological darkblue 524, 49 131, 11 131, 15 131, 11 131, 12 0.0532 0.12 0.657 0.1825 1.05 0.834 1.33 0.28 0.402 0.486 0.313 1.32 0.602 2.91 -0.0868 0.429 0.84 0.07582 0.917 0.395 2.13 0.162 0.421 0.7 0.1549 1.18 0.515 2.69 PRS_PLINK_0.001 TRUE 334 Degenerative disease of the spinal cord Both 289 3878 6 neurological darkblue 3878, 289 970, 78 969, 61 969, 67 970, 83 0.0384 0.0411 0.35 0.456 1.04 0.959 1.13 -0.245 0.175 0.161 0.7924 0.783 0.555 1.1 -0.154 0.171 0.367 0.4356 0.857 0.613 1.2 0.0623 0.163 0.702 0.1535 1.06 0.773 1.46 PRS_PLINK_0.001 FALSE 334.1 Spinocerebellar disease Both 11 263 6 neurological darkblue 263, 11 66, 5 66, 4 65, 2 66, 0 -2.1 1.03 0.0407 1.39 0.122 0.0163 0.915 -0.241 0.632 0.703 0.1533 0.786 0.228 2.71 -0.487 0.714 0.495 0.3052 0.615 0.152 2.49 -2.2 1.19 0.0659 1.181 0.111 0.0107 1.16 PRS_PLINK_0.001 TRUE 334.2 Anterior horn cell disease Both 34 505 6 neurological darkblue 505, 34 127, 8 126, 7 126, 5 126, 14 0.138 0.513 0.788 0.1037 1.15 0.42 3.14 -0.116 0.503 0.818 0.08746 0.891 0.332 2.39 -0.376 0.53 0.478 0.3208 0.686 0.243 1.94 0.516 0.438 0.238 0.6225 1.68 0.71 3.95 PRS_PLINK_0.001 TRUE 335 Multiple sclerosis Both 241 3046 6 neurological darkblue 3046, 241 762, 59 761, 58 761, 57 762, 67 -0.0204 0.0702 0.771 0.1129 0.98 0.854 1.12 -0.0215 0.19 0.91 0.04109 0.979 0.675 1.42 -0.0421 0.19 0.825 0.08356 0.959 0.66 1.39 0.105 0.184 0.57 0.2439 1.11 0.774 1.59 PRS_PLINK_0.001 FALSE 337 Disorders of the autonomic nervous system Both 39 561 6 neurological darkblue 561, 39 141, 11 140, 7 140, 7 140, 14 -0.0933 0.549 0.865 0.0629 0.911 0.31 2.67 -0.516 0.474 0.276 0.5586 0.597 0.236 1.51 -0.502 0.474 0.289 0.5392 0.605 0.239 1.53 0.294 0.402 0.464 0.3335 1.34 0.611 2.95 PRS_PLINK_0.001 TRUE 337.1 Peripheral autonomic neuropathy Both 11 130 6 neurological darkblue 130, 11 33, 3 32, 2 32, 1 33, 5 0.17 0.859 0.843 0.07418 1.19 0.22 6.38 -0.272 0.777 0.727 0.1387 0.762 0.166 3.49 -1.3 1.1 0.237 0.6259 0.271 0.0312 2.35 0.883 0.868 0.309 0.5097 2.42 0.441 13.3 PRS_PLINK_0.001 TRUE 338 Pain Both 137 1684 6 neurological darkblue 1684, 137 420, 31 421, 32 421, 34 421, 40 0.083 0.0397 0.0364 1.439 1.09 1.01 1.17 0.00342 0.257 0.989 0.004636 1 0.606 1.66 0.0213 0.254 0.933 0.03004 1.02 0.621 1.68 0.235 0.245 0.337 0.4719 1.26 0.783 2.04 PRS_PLINK_0.001 FALSE 338.1 Acute pain Both 75 850 6 neurological darkblue 850, 75 212, 15 212, 16 212, 21 213, 23 0.135 0.0726 0.0638 1.195 1.14 0.992 1.32 0.154 0.361 0.669 0.1746 1.17 0.575 2.37 0.249 0.346 0.471 0.3266 1.28 0.651 2.53 0.336 0.336 0.318 0.4978 1.4 0.724 2.71 PRS_PLINK_0.001 FALSE 338.2 Chronic pain Both 62 874 6 neurological darkblue 874, 62 219, 16 218, 16 218, 13 219, 17 0.205 0.114 0.0737 1.133 1.23 0.981 1.54 0.0049 0.352 0.989 0.004847 1 0.504 2 -0.188 0.368 0.609 0.2156 0.828 0.403 1.7 0.117 0.347 0.736 0.1329 1.12 0.569 2.22 PRS_PLINK_0.001 FALSE 339 Other headache syndromes Both 1272 16838 6 neurological darkblue 16838, 1272 4210, 326 4209, 323 4209, 297 4210, 326 0.0109 0.0275 0.692 0.1601 1.01 0.958 1.07 -0.00801 0.0813 0.921 0.03551 0.992 0.846 1.16 -0.0907 0.0829 0.274 0.562 0.913 0.776 1.07 -0.00302 0.0812 0.97 0.0131 0.997 0.85 1.17 PRS_PLINK_0.001 FALSE 340 Migraine Both 530 6298 6 neurological darkblue 6298, 530 1575, 143 1574, 137 1574, 123 1575, 127 0.00532 0.0542 0.922 0.03532 1.01 0.904 1.12 -0.042 0.124 0.735 0.1336 0.959 0.752 1.22 -0.154 0.128 0.226 0.6454 0.857 0.667 1.1 -0.116 0.126 0.359 0.4455 0.89 0.695 1.14 PRS_PLINK_0.001 FALSE 340.1 Migrain with aura Both 40 489 6 neurological darkblue 489, 40 123, 13 122, 12 122, 6 122, 9 -0.728 0.539 0.177 0.753 0.483 0.168 1.39 -0.0708 0.407 0.862 0.06451 0.932 0.419 2.07 -0.89 0.48 0.0639 1.195 0.411 0.16 1.05 -0.357 0.435 0.412 0.3846 0.7 0.298 1.64 PRS_PLINK_0.001 TRUE 341 Other demyelinating diseases of central nervous system Both 56 553 6 neurological darkblue 553, 56 138, 11 138, 17 138, 20 138, 8 -0.224 0.433 0.605 0.2185 0.799 0.342 1.87 0.43 0.391 0.271 0.5663 1.54 0.714 3.31 0.51 0.381 0.18 0.7448 1.67 0.79 3.51 -0.246 0.448 0.583 0.2346 0.782 0.325 1.88 PRS_PLINK_0.001 FALSE 342 Hemiplegia Both 183 3113 6 neurological darkblue 3113, 183 779, 59 778, 52 778, 36 778, 36 -0.711 0.247 0.004 2.398 0.491 0.303 0.797 -0.132 0.195 0.497 0.3038 0.876 0.598 1.28 -0.501 0.214 0.0195 1.71 0.606 0.398 0.923 -0.501 0.214 0.0195 1.71 0.606 0.398 0.923 PRS_PLINK_0.001 FALSE 343 Infantile cerebral palsy Both 25 310 6 neurological darkblue 310, 25 78, 5 77, 10 77, 3 78, 7 0.135 0.693 0.846 0.07286 1.14 0.294 4.45 0.688 0.573 0.23 0.6377 1.99 0.647 6.12 -0.317 0.716 0.658 0.1818 0.728 0.179 2.96 0.169 0.613 0.783 0.1064 1.18 0.356 3.94 PRS_PLINK_0.001 TRUE 344 Other paralytic syndromes Both 105 1449 6 neurological darkblue 1449, 105 363, 34 362, 21 362, 27 362, 23 -0.589 0.327 0.0721 1.142 0.555 0.292 1.05 -0.438 0.279 0.117 0.9327 0.645 0.373 1.12 -0.231 0.263 0.378 0.422 0.794 0.474 1.33 -0.377 0.273 0.167 0.7771 0.686 0.402 1.17 PRS_PLINK_0.001 FALSE 345 Epilepsy, recurrent seizures, convulsions Both 760 10674 6 neurological darkblue 10674, 760 2669, 191 2668, 197 2668, 182 2669, 190 0.0159 0.035 0.65 0.1872 1.02 0.949 1.09 0.0412 0.105 0.695 0.1582 1.04 0.848 1.28 -0.0465 0.107 0.663 0.1784 0.955 0.774 1.18 -0.000421 0.106 0.997 0.001382 1 0.813 1.23 PRS_PLINK_0.001 FALSE 345.1 Epilepsy Both 142 1901 6 neurological darkblue 1901, 142 476, 44 475, 40 475, 26 475, 32 -0.499 0.282 0.0771 1.113 0.607 0.349 1.06 -0.0994 0.224 0.657 0.1822 0.905 0.584 1.4 -0.539 0.251 0.0317 1.499 0.583 0.357 0.954 -0.321 0.237 0.175 0.756 0.725 0.456 1.15 PRS_PLINK_0.001 FALSE 345.11 Generalized convulsive epilepsy Both 71 974 6 neurological darkblue 974, 71 244, 21 243, 20 243, 14 244, 16 -0.343 0.384 0.372 0.4296 0.71 0.335 1.51 -0.0975 0.316 0.758 0.1206 0.907 0.488 1.69 -0.392 0.342 0.251 0.6004 0.676 0.346 1.32 -0.292 0.332 0.379 0.4209 0.747 0.389 1.43 PRS_PLINK_0.001 FALSE 345.12 Partial epilepsy Both 44 599 6 neurological darkblue 599, 44 150, 16 150, 10 149, 8 150, 10 -0.32 0.492 0.516 0.2873 0.727 0.277 1.91 -0.484 0.407 0.235 0.6286 0.617 0.277 1.37 -0.608 0.424 0.152 0.8193 0.545 0.237 1.25 -0.457 0.397 0.25 0.6023 0.633 0.291 1.38 PRS_PLINK_0.001 TRUE 345.3 Convulsions Both 312 4741 6 neurological darkblue 4741, 312 1186, 86 1185, 79 1185, 71 1185, 76 -0.0614 0.0942 0.515 0.2886 0.94 0.782 1.13 -0.0797 0.16 0.618 0.209 0.923 0.675 1.26 -0.189 0.164 0.25 0.6026 0.828 0.601 1.14 -0.112 0.161 0.489 0.311 0.894 0.652 1.23 PRS_PLINK_0.001 FALSE 346.1 Nonspecific abnormal findings on radiological and other examination of skull and head Both 29 289 6 neurological darkblue 289, 29 73, 7 72, 9 72, 6 72, 7 -0.0202 0.646 0.975 0.01099 0.98 0.276 3.47 0.21 0.512 0.681 0.1668 1.23 0.453 3.36 -0.0938 0.536 0.861 0.0649 0.91 0.318 2.61 0.0716 0.533 0.893 0.0491 1.07 0.378 3.05 PRS_PLINK_0.001 TRUE 348 Other conditions of brain Both 110 1698 6 neurological darkblue 1698, 110 425, 25 424, 33 424, 28 425, 24 0.0429 0.1 0.669 0.1746 1.04 0.858 1.27 0.31 0.268 0.247 0.6067 1.36 0.807 2.3 0.129 0.276 0.641 0.193 1.14 0.662 1.96 -0.01 0.286 0.972 0.01232 0.99 0.566 1.73 PRS_PLINK_0.001 FALSE 348.2 Cerebral edema and compression of brain Both 41 594 6 neurological darkblue 594, 41 149, 9 148, 12 148, 8 149, 12 0.0878 0.114 0.443 0.3538 1.09 0.873 1.37 0.261 0.426 0.54 0.2676 1.3 0.563 3 -0.0389 0.474 0.935 0.02939 0.962 0.38 2.43 0.268 0.429 0.533 0.2733 1.31 0.563 3.03 PRS_PLINK_0.001 TRUE 348.4 Cerebral cysts Both 27 278 6 neurological darkblue 278, 27 70, 4 69, 12 69, 6 70, 5 0.0832 0.679 0.903 0.04455 1.09 0.287 4.11 1.01 0.554 0.0682 1.166 2.75 0.927 8.13 0.444 0.601 0.461 0.3365 1.56 0.479 5.06 0.21 0.6 0.726 0.1388 1.23 0.38 4 PRS_PLINK_0.001 TRUE 348.7 Coma Both 62 766 6 neurological darkblue 766, 62 192, 13 191, 25 191, 13 192, 11 0.0105 0.0945 0.911 0.04035 1.01 0.84 1.22 0.64 0.352 0.0688 1.162 1.9 0.952 3.78 -0.0443 0.387 0.909 0.04148 0.957 0.448 2.04 -0.173 0.404 0.67 0.1742 0.842 0.381 1.86 PRS_PLINK_0.001 FALSE 348.8 Encephalopathy, not elsewhere classified Both 26 554 6 neurological darkblue 554, 26 139, 5 138, 5 138, 9 139, 7 0.104 0.122 0.392 0.4072 1.11 0.874 1.41 0.065 0.566 0.909 0.04162 1.07 0.352 3.24 0.439 0.521 0.399 0.399 1.55 0.559 4.31 0.486 0.543 0.371 0.4302 1.62 0.56 4.71 PRS_PLINK_0.001 TRUE 348.9 Other conditions of brain, NOS Both 66 879 6 neurological darkblue 879, 66 220, 23 220, 17 219, 14 220, 12 -0.762 0.392 0.0522 1.283 0.467 0.216 1.01 -0.35 0.325 0.282 0.5495 0.705 0.373 1.33 -0.506 0.343 0.14 0.8531 0.603 0.308 1.18 -0.616 0.356 0.0837 1.077 0.54 0.268 1.09 PRS_PLINK_0.001 FALSE 349 Other and unspecified disorders of the nervous system Both 55 788 6 neurological darkblue 788, 55 197, 17 197, 14 197, 13 197, 11 0.094 0.121 0.437 0.3597 1.1 0.867 1.39 -0.15 0.361 0.677 0.1692 0.86 0.424 1.75 -0.221 0.368 0.548 0.2613 0.801 0.389 1.65 -0.448 0.384 0.242 0.6154 0.639 0.301 1.35 PRS_PLINK_0.001 FALSE 350 Abnormal movement Both 384 5355 6 neurological darkblue 5355, 384 1339, 102 1339, 110 1338, 83 1339, 89 0.0446 0.0355 0.21 0.6785 1.05 0.975 1.12 0.0763 0.142 0.591 0.2284 1.08 0.817 1.43 -0.197 0.152 0.193 0.714 0.821 0.61 1.11 -0.138 0.149 0.355 0.4494 0.871 0.651 1.17 PRS_PLINK_0.001 FALSE 350.1 Abnormal involuntary movements Both 137 1770 6 neurological darkblue 1770, 137 443, 36 442, 38 442, 27 443, 36 0.0949 0.0623 0.127 0.8946 1.1 0.973 1.24 0.0613 0.238 0.797 0.09854 1.06 0.667 1.7 -0.235 0.259 0.364 0.4392 0.79 0.475 1.31 -0.00195 0.242 0.994 0.002802 0.998 0.622 1.6 PRS_PLINK_0.001 FALSE 350.2 Abnormality of gait Both 196 3105 6 neurological darkblue 3105, 196 777, 55 776, 54 776, 41 776, 46 0.0536 0.0471 0.255 0.5936 1.06 0.962 1.16 -0.0137 0.196 0.944 0.02486 0.986 0.672 1.45 -0.276 0.209 0.187 0.7286 0.759 0.503 1.14 -0.182 0.203 0.371 0.4312 0.834 0.56 1.24 PRS_PLINK_0.001 FALSE 350.3 Lack of coordination Both 66 739 6 neurological darkblue 739, 66 185, 16 185, 20 184, 17 185, 13 0.0499 0.147 0.734 0.1345 1.05 0.789 1.4 0.225 0.342 0.511 0.2919 1.25 0.64 2.45 -0.0154 0.358 0.966 0.01517 0.985 0.488 1.99 -0.212 0.374 0.57 0.2439 0.809 0.389 1.68 PRS_PLINK_0.001 FALSE 350.6 Disturbances of sensation of smell and taste Both 9 119 6 neurological darkblue 119, 9 30, 1 30, 2 29, 5 30, 1 0.419 1.23 0.734 0.1343 1.52 0.136 17 0.427 0.977 0.662 0.1791 1.53 0.226 10.4 0.784 0.893 0.38 0.4202 2.19 0.381 12.6 0.0661 0.961 0.945 0.02447 1.07 0.162 7.03 PRS_PLINK_0.001 TRUE 351 Other peripheral nerve disorders Both 2247 26636 6 neurological darkblue 26636, 2247 6659, 565 6659, 542 6659, 549 6659, 590 0.0178 0.0187 0.342 0.4661 1.02 0.981 1.06 -0.04 0.0625 0.522 0.2822 0.961 0.85 1.09 -0.0288 0.0623 0.644 0.1911 0.972 0.86 1.1 0.0441 0.0613 0.472 0.3262 1.05 0.927 1.18 PRS_PLINK_0.001 FALSE 352 Disorders of other cranial nerves Both 248 2893 6 neurological darkblue 2893, 248 724, 62 723, 59 723, 67 723, 60 -0.00971 0.0629 0.877 0.05684 0.99 0.875 1.12 -0.0642 0.187 0.732 0.1354 0.938 0.65 1.35 0.0773 0.182 0.672 0.1727 1.08 0.756 1.54 -0.00968 0.187 0.959 0.01834 0.99 0.687 1.43 PRS_PLINK_0.001 FALSE 352.1 Trigeminal nerve disorders [CN5] Both 77 992 6 neurological darkblue 992, 77 248, 18 248, 18 248, 21 248, 20 0.0204 0.0675 0.763 0.1174 1.02 0.894 1.17 -0.0458 0.336 0.892 0.04983 0.955 0.494 1.85 0.157 0.324 0.627 0.2025 1.17 0.621 2.21 0.128 0.326 0.694 0.1588 1.14 0.6 2.15 PRS_PLINK_0.001 FALSE 352.2 Facial nerve disorders [CN7] Both 164 1830 6 neurological darkblue 1830, 164 458, 42 457, 37 457, 40 458, 45 0.0401 0.0757 0.597 0.2243 1.04 0.897 1.21 -0.111 0.231 0.63 0.2004 0.895 0.569 1.41 -0.059 0.229 0.796 0.09885 0.943 0.602 1.48 0.102 0.222 0.646 0.1894 1.11 0.717 1.71 PRS_PLINK_0.001 FALSE 353 Nerve root and plexus disorders Both 179 2376 6 neurological darkblue 2376, 179 594, 40 594, 48 594, 38 594, 53 0.00978 0.0616 0.874 0.05854 1.01 0.895 1.14 0.174 0.218 0.425 0.3715 1.19 0.776 1.83 -0.0374 0.23 0.871 0.05994 0.963 0.614 1.51 0.292 0.215 0.173 0.7614 1.34 0.88 2.04 PRS_PLINK_0.001 FALSE 353.1 Nerve plexus lesions Both 20 273 6 neurological darkblue 273, 20 69, 6 68, 5 68, 7 68, 2 -0.894 0.753 0.235 0.6285 0.409 0.0934 1.79 -0.313 0.585 0.593 0.2272 0.731 0.232 2.3 0.0253 0.55 0.963 0.01624 1.03 0.349 3.02 -1.22 0.756 0.108 0.9685 0.296 0.0673 1.3 PRS_PLINK_0.001 TRUE 353.2 Nerve root lesions Both 6 108 6 neurological darkblue 108, 6 27, 1 27, 3 27, 0 27, 2 1.96 1.25 0.117 0.9314 7.13 0.611 83.2 0.61 1.18 0.605 0.2183 1.84 0.183 18.5 -0.126 1.22 0.918 0.03726 0.882 0.0811 9.58 0.528 0.96 0.583 0.2347 1.7 0.258 11.1 PRS_PLINK_0.001 TRUE 356 Hereditary and idiopathic peripheral neuropathy Both 32 324 6 neurological darkblue 324, 32 81, 8 81, 8 81, 7 81, 9 -0.505 0.568 0.374 0.4268 0.603 0.198 1.84 0.0247 0.5 0.961 0.01746 1.03 0.385 2.73 -0.345 0.53 0.515 0.2878 0.708 0.251 2 -0.125 0.501 0.802 0.0957 0.882 0.331 2.35 PRS_PLINK_0.001 TRUE 357 Inflammatory and toxic neuropathy Both 264 2828 6 neurological darkblue 2828, 264 707, 61 707, 82 707, 50 707, 71 -0.00302 0.0852 0.972 0.01244 0.997 0.844 1.18 0.288 0.176 0.101 0.9949 1.33 0.945 1.88 -0.187 0.196 0.341 0.4672 0.83 0.565 1.22 0.138 0.181 0.445 0.3516 1.15 0.805 1.64 PRS_PLINK_0.001 FALSE 358 Myoneural disorders Both 42 431 6 neurological darkblue 431, 42 108, 12 108, 8 107, 13 108, 9 -0.621 0.548 0.257 0.5907 0.537 0.184 1.57 -0.418 0.451 0.354 0.4511 0.659 0.272 1.59 0.137 0.41 0.739 0.1314 1.15 0.513 2.56 -0.258 0.437 0.555 0.2559 0.773 0.328 1.82 PRS_PLINK_0.001 TRUE 358.1 Myasthenia gravis Both 37 413 6 neurological darkblue 413, 37 104, 9 103, 11 103, 8 103, 9 -0.53 0.56 0.345 0.4627 0.589 0.196 1.77 0.183 0.451 0.685 0.1641 1.2 0.496 2.91 -0.00854 0.48 0.986 0.006215 0.991 0.387 2.54 0.00287 0.463 0.995 0.002154 1 0.405 2.49 PRS_PLINK_0.001 TRUE 359 Muscular dystrophies and other myopathies Both 87 1010 6 neurological darkblue 1010, 87 253, 27 252, 22 252, 20 253, 18 -0.624 0.38 0.101 0.9976 0.536 0.254 1.13 -0.248 0.299 0.407 0.3907 0.78 0.434 1.4 -0.283 0.301 0.347 0.4603 0.753 0.417 1.36 -0.403 0.31 0.194 0.7125 0.668 0.364 1.23 PRS_PLINK_0.001 FALSE 359.1 Muscular dystrophies Both 19 290 6 neurological darkblue 290, 19 73, 6 72, 6 72, 4 73, 3 -0.789 0.759 0.299 0.5244 0.454 0.103 2.01 0.132 0.563 0.815 0.08896 1.14 0.379 3.44 -0.534 0.61 0.382 0.4181 0.586 0.177 1.94 -1.04 0.694 0.135 0.8684 0.355 0.091 1.38 PRS_PLINK_0.001 TRUE 359.2 Myopathy Both 72 753 6 neurological darkblue 753, 72 189, 21 188, 16 188, 17 188, 18 0.00328 0.0731 0.964 0.01582 1 0.869 1.16 -0.266 0.344 0.439 0.3575 0.766 0.39 1.5 -0.17 0.334 0.611 0.2139 0.844 0.438 1.62 -0.132 0.329 0.689 0.1617 0.877 0.46 1.67 PRS_PLINK_0.001 FALSE 360 Disorders of the globe Both 89 745 7 sense organs darkseagreen4 745, 89 187, 21 186, 26 186, 24 186, 18 -0.0207 0.0867 0.812 0.0907 0.98 0.827 1.16 0.229 0.308 0.457 0.3405 1.26 0.688 2.3 0.195 0.313 0.534 0.2726 1.22 0.658 2.25 -0.0649 0.33 0.844 0.07351 0.937 0.49 1.79 PRS_PLINK_0.001 FALSE 360.2 Progressive myopia Both 71 550 7 sense organs darkseagreen4 550, 71 138, 16 137, 20 137, 19 138, 16 -0.00533 0.0915 0.954 0.02066 0.995 0.831 1.19 0.197 0.351 0.575 0.2405 1.22 0.612 2.42 0.267 0.356 0.454 0.3432 1.31 0.65 2.62 0.0812 0.367 0.825 0.08362 1.08 0.528 2.23 PRS_PLINK_0.001 FALSE 361 Retinal detachments and defects Both 759 6855 7 sense organs darkseagreen4 6855, 759 1714, 176 1714, 204 1713, 191 1714, 188 0.0141 0.034 0.678 0.1687 1.01 0.949 1.08 0.141 0.108 0.191 0.719 1.15 0.932 1.42 0.0867 0.11 0.43 0.3669 1.09 0.879 1.35 0.0646 0.11 0.557 0.254 1.07 0.86 1.32 PRS_PLINK_0.001 FALSE 361.1 Retinal detachment with retinal defect Both 329 2948 7 sense organs darkseagreen4 2948, 329 737, 74 737, 92 737, 81 737, 82 0.0423 0.051 0.407 0.3904 1.04 0.944 1.15 0.214 0.164 0.192 0.7172 1.24 0.898 1.71 0.116 0.168 0.49 0.3095 1.12 0.808 1.56 0.107 0.167 0.524 0.2805 1.11 0.801 1.54 PRS_PLINK_0.001 FALSE 361.2 Retinoschisis and retinal cysts Both 16 130 7 sense organs darkseagreen4 130, 16 33, 2 32, 4 32, 6 33, 4 0.51 0.935 0.585 0.2326 1.67 0.266 10.4 0.303 0.859 0.724 0.1401 1.35 0.252 7.28 0.95 0.764 0.214 0.6702 2.58 0.579 11.5 0.565 0.783 0.47 0.3277 1.76 0.38 8.16 PRS_PLINK_0.001 TRUE 362 Other retinal disorders Both 709 7707 7 sense organs darkseagreen4 7707, 709 1927, 176 1927, 178 1926, 190 1927, 165 -0.0804 0.0713 0.259 0.5862 0.923 0.802 1.06 0.0133 0.111 0.904 0.04379 1.01 0.816 1.26 0.0803 0.109 0.462 0.3354 1.08 0.875 1.34 -0.0664 0.113 0.556 0.2553 0.936 0.75 1.17 PRS_PLINK_0.001 FALSE 362.2 Degeneration of macula and posterior pole of retina Both 392 4257 7 sense organs darkseagreen4 4257, 392 1065, 89 1064, 112 1064, 106 1064, 85 -0.041 0.0891 0.646 0.1901 0.96 0.806 1.14 0.234 0.148 0.113 0.9462 1.26 0.946 1.69 0.185 0.149 0.214 0.6693 1.2 0.898 1.61 -0.0331 0.157 0.833 0.07943 0.967 0.712 1.32 PRS_PLINK_0.001 FALSE 362.29 Macular degeneration (senile) of retina NOS Both 392 4247 7 sense organs darkseagreen4 4247, 392 1062, 90 1062, 110 1061, 107 1062, 85 -0.0422 0.0897 0.638 0.195 0.959 0.804 1.14 0.203 0.148 0.17 0.7693 1.22 0.917 1.64 0.185 0.149 0.214 0.67 1.2 0.899 1.61 -0.0443 0.156 0.777 0.1095 0.957 0.704 1.3 PRS_PLINK_0.001 FALSE 362.3 Other nondiabetic retinopathy Both 45 339 7 sense organs darkseagreen4 339, 45 85, 11 85, 9 84, 7 85, 18 0.0753 0.122 0.537 0.2703 1.08 0.849 1.37 -0.0685 0.459 0.881 0.05488 0.934 0.38 2.29 -0.302 0.484 0.532 0.2743 0.739 0.286 1.91 0.483 0.408 0.237 0.6258 1.62 0.728 3.61 PRS_PLINK_0.001 TRUE 362.31 Separation of retinal layers Both 30 210 7 sense organs darkseagreen4 210, 30 53, 6 52, 8 52, 5 53, 11 0.261 0.619 0.673 0.1721 1.3 0.386 4.37 0.375 0.58 0.518 0.2857 1.46 0.467 4.54 -0.053 0.588 0.928 0.03236 0.948 0.3 3 0.439 0.521 0.399 0.3986 1.55 0.559 4.31 PRS_PLINK_0.001 TRUE 362.4 Retinal vascular changes and abnomalities Both 135 1726 7 sense organs darkseagreen4 1726, 135 432, 40 431, 31 431, 35 432, 29 -0.0234 0.0863 0.786 0.1045 0.977 0.825 1.16 -0.228 0.245 0.352 0.4537 0.796 0.493 1.29 -0.11 0.237 0.644 0.1908 0.896 0.563 1.43 -0.325 0.248 0.19 0.7216 0.722 0.444 1.17 PRS_PLINK_0.001 FALSE 362.6 Peripheral retinal degenerations Both 47 383 7 sense organs darkseagreen4 383, 47 96, 14 96, 12 95, 9 96, 12 0.0325 0.126 0.796 0.09883 1.03 0.807 1.32 -0.145 0.417 0.728 0.1379 0.865 0.382 1.96 -0.478 0.439 0.277 0.5576 0.62 0.262 1.47 -0.17 0.404 0.674 0.1716 0.843 0.382 1.86 PRS_PLINK_0.001 TRUE 362.7 Hereditary retinal dystrophies Both 13 160 7 sense organs darkseagreen4 160, 13 40, 3 40, 3 40, 4 40, 3 0.179 0.867 0.837 0.07749 1.2 0.218 6.55 0.0184 0.737 0.98 0.008746 1.02 0.24 4.32 -0.152 0.759 0.842 0.0749 0.859 0.194 3.81 PRS_PLINK_0.001 TRUE 362.8 Retinal hemorrhage/ischemia Both 22 272 7 sense organs darkseagreen4 272, 22 68, 6 68, 7 68, 6 68, 3 -0.724 0.783 0.355 0.4494 0.485 0.104 2.25 0.207 0.56 0.712 0.1477 1.23 0.411 3.68 0.194 0.56 0.729 0.1373 1.21 0.405 3.64 -0.0488 0.687 0.943 0.02531 0.952 0.248 3.66 PRS_PLINK_0.001 TRUE 363 Chorioretinal inflammations, scars, and other disorders of choroid Both 37 360 7 sense organs darkseagreen4 360, 37 90, 11 90, 9 90, 11 90, 6 -0.453 0.564 0.422 0.3743 0.636 0.211 1.92 -0.169 0.454 0.711 0.1484 0.845 0.347 2.06 -0.0117 0.436 0.979 0.009368 0.988 0.421 2.32 -0.584 0.497 0.24 0.6201 0.558 0.211 1.48 PRS_PLINK_0.001 TRUE 363.3 Chorioretinal scars Both 14 146 7 sense organs darkseagreen4 146, 14 37, 5 36, 2 36, 5 37, 2 -0.817 0.906 0.367 0.4354 0.442 0.0749 2.61 -0.429 0.767 0.576 0.2396 0.651 0.145 2.93 0.162 0.658 0.806 0.09389 1.18 0.324 4.27 -0.806 0.811 0.32 0.4944 0.447 0.0911 2.19 PRS_PLINK_0.001 TRUE 364 Corneal opacity and other disorders of cornea Both 121 1300 7 sense organs darkseagreen4 1300, 121 325, 30 325, 30 325, 33 325, 28 -0.00432 0.1 0.966 0.01519 0.996 0.818 1.21 -0.0039 0.265 0.988 0.005131 0.996 0.593 1.67 0.0574 0.261 0.826 0.08305 1.06 0.635 1.77 -0.083 0.268 0.757 0.1209 0.92 0.544 1.56 PRS_PLINK_0.001 FALSE 364.1 Corneal opacity Both 9 225 7 sense organs darkseagreen4 225, 9 57, 1 56, 4 56, 1 56, 3 1.08 0.853 0.204 0.6911 2.96 0.556 15.8 -0.101 0.928 0.913 0.03937 0.904 0.147 5.57 1.06 0.85 0.211 0.6756 2.89 0.547 15.3 PRS_PLINK_0.001 TRUE 364.2 Corneal edema Both 13 159 7 sense organs darkseagreen4 159, 13 40, 1 40, 6 39, 3 40, 3 0.754 0.89 0.397 0.4017 2.13 0.372 12.2 1.72 0.96 0.0733 1.135 5.58 0.85 36.6 1.35 1.03 0.189 0.7234 3.88 0.513 29.3 0.791 0.873 0.364 0.4384 2.21 0.399 12.2 PRS_PLINK_0.001 TRUE 364.4 Corneal degenerations Both 30 408 7 sense organs darkseagreen4 408, 30 102, 10 102, 6 102, 5 102, 9 0.047 0.105 0.654 0.1844 1.05 0.853 1.29 -0.546 0.518 0.292 0.5352 0.579 0.21 1.6 -0.653 0.536 0.224 0.6505 0.521 0.182 1.49 -0.109 0.459 0.811 0.09074 0.896 0.365 2.2 PRS_PLINK_0.001 TRUE 364.41 Keratoconus Both 18 203 7 sense organs darkseagreen4 203, 18 51, 5 51, 5 50, 3 51, 5 -0.484 0.851 0.569 0.2447 0.616 0.116 3.26 0.0192 0.614 0.975 0.01096 1.02 0.306 3.4 -0.516 0.741 0.486 0.3129 0.597 0.14 2.55 -0.0183 0.659 0.978 0.009737 0.982 0.27 3.58 PRS_PLINK_0.001 TRUE 364.5 Corneal dystrophy Both 48 406 7 sense organs darkseagreen4 406, 48 102, 9 101, 12 101, 14 102, 13 0.312 0.496 0.53 0.276 1.37 0.517 3.61 0.249 0.44 0.573 0.2422 1.28 0.541 3.04 0.389 0.431 0.367 0.4356 1.48 0.634 3.43 0.471 0.454 0.3 0.5233 1.6 0.658 3.9 PRS_PLINK_0.001 TRUE 364.9 Cornea replaced by transplant Both 23 203 7 sense organs darkseagreen4 203, 23 51, 6 51, 9 50, 5 51, 3 -0.855 0.792 0.28 0.5524 0.425 0.0901 2.01 0.393 0.565 0.487 0.3123 1.48 0.489 4.49 -0.12 0.606 0.843 0.0741 0.887 0.27 2.91 -0.506 0.73 0.488 0.3113 0.603 0.144 2.52 PRS_PLINK_0.001 TRUE 365 Glaucoma Both 822 8842 7 sense organs darkseagreen4 8842, 822 2211, 191 2210, 193 2210, 235 2211, 203 0.0042 0.0305 0.89 0.05045 1 0.946 1.07 0.00583 0.106 0.956 0.01947 1.01 0.817 1.24 0.205 0.102 0.0441 1.355 1.23 1.01 1.5 0.0568 0.105 0.588 0.2303 1.06 0.862 1.3 PRS_PLINK_0.001 FALSE 365.1 Open-angle glaucoma Both 203 2078 7 sense organs darkseagreen4 2078, 203 520, 45 519, 52 519, 54 520, 52 0.0265 0.0815 0.745 0.128 1.03 0.875 1.2 0.172 0.21 0.414 0.3827 1.19 0.786 1.79 0.141 0.21 0.504 0.2979 1.15 0.762 1.74 0.149 0.21 0.478 0.3208 1.16 0.769 1.75 PRS_PLINK_0.001 FALSE 365.11 Primary open angle glaucoma Both 202 2061 7 sense organs darkseagreen4 2061, 202 516, 45 515, 51 515, 56 515, 50 0.0267 0.0816 0.744 0.1287 1.03 0.875 1.21 0.155 0.211 0.462 0.3353 1.17 0.772 1.77 0.189 0.209 0.365 0.4382 1.21 0.803 1.82 0.111 0.212 0.601 0.2211 1.12 0.737 1.69 PRS_PLINK_0.001 FALSE 365.2 Primary angle-closure glaucoma Both 106 1362 7 sense organs darkseagreen4 1362, 106 341, 22 340, 20 340, 39 341, 25 0.0241 0.0565 0.67 0.1741 1.02 0.917 1.14 -0.108 0.31 0.728 0.1377 0.898 0.489 1.65 0.576 0.272 0.0343 1.464 1.78 1.04 3.03 0.122 0.293 0.679 0.1683 1.13 0.635 2.01 PRS_PLINK_0.001 FALSE 366 Cataract Both 3674 34687 7 sense organs darkseagreen4 34687, 3674 8671, 937 8672, 932 8671, 874 8672, 931 0.00434 0.0156 0.782 0.107 1 0.974 1.04 0.000186 0.0487 0.997 0.001326 1 0.909 1.1 -0.0642 0.0495 0.195 0.711 0.938 0.851 1.03 -0.000536 0.0487 0.991 0.003825 0.999 0.908 1.1 PRS_PLINK_0.001 FALSE 366.1 Nonsenile Cataract Both 20 154 7 sense organs darkseagreen4 154, 20 39, 6 38, 1 38, 5 39, 8 1.05 0.656 0.109 0.9636 2.86 0.792 10.4 -1.8 0.914 0.049 1.31 0.165 0.0275 0.992 -0.356 0.728 0.625 0.2041 0.701 0.168 2.92 0.316 0.57 0.58 0.2368 1.37 0.449 4.19 PRS_PLINK_0.001 TRUE 366.2 Senile cataract Both 1476 15947 7 sense organs darkseagreen4 15947, 1476 3986, 372 3987, 357 3986, 338 3987, 409 0.0231 0.0224 0.303 0.5191 1.02 0.979 1.07 -0.0419 0.0773 0.588 0.2306 0.959 0.824 1.12 -0.0937 0.0783 0.231 0.6356 0.911 0.781 1.06 0.0961 0.075 0.2 0.6994 1.1 0.95 1.28 PRS_PLINK_0.001 FALSE 366.3 Traumatic cataract Both 16 193 7 sense organs darkseagreen4 193, 16 49, 6 48, 3 48, 5 48, 2 -0.558 0.874 0.523 0.2813 0.572 0.103 3.18 -0.809 0.711 0.255 0.5937 0.445 0.111 1.79 0.115 0.614 0.851 0.07 1.12 0.337 3.74 -0.989 0.754 0.19 0.7223 0.372 0.0849 1.63 PRS_PLINK_0.001 TRUE 367 Disorders of refraction and accommodation; blindness and low vision Both 477 4987 7 sense organs darkseagreen4 4987, 477 1247, 120 1247, 108 1246, 128 1247, 121 -0.0386 0.0667 0.563 0.2492 0.962 0.844 1.1 -0.106 0.138 0.442 0.3544 0.9 0.687 1.18 0.0777 0.133 0.558 0.2533 1.08 0.833 1.4 0.0127 0.134 0.925 0.03401 1.01 0.778 1.32 PRS_PLINK_0.001 FALSE 367.1 Myopia Both 295 2667 7 sense organs darkseagreen4 2667, 295 667, 82 667, 65 666, 73 667, 75 -0.0359 0.0804 0.655 0.1834 0.965 0.824 1.13 -0.23 0.174 0.185 0.7329 0.794 0.565 1.12 -0.102 0.169 0.546 0.2627 0.903 0.649 1.26 -0.0957 0.168 0.568 0.2455 0.909 0.654 1.26 PRS_PLINK_0.001 FALSE 367.2 Astigmatism Both 42 397 7 sense organs darkseagreen4 397, 42 100, 8 99, 8 99, 14 99, 12 0.0275 0.119 0.817 0.08778 1.03 0.814 1.3 -0.104 0.493 0.832 0.07974 0.901 0.343 2.37 0.377 0.445 0.397 0.4009 1.46 0.609 3.49 0.291 0.462 0.529 0.2769 1.34 0.541 3.31 PRS_PLINK_0.001 TRUE 367.8 Hypermetropia Both 48 493 7 sense organs darkseagreen4 493, 48 124, 7 123, 11 123, 18 123, 12 0.324 0.471 0.493 0.3076 1.38 0.549 3.48 0.365 0.461 0.428 0.3683 1.44 0.584 3.56 0.903 0.439 0.0394 1.405 2.47 1.04 5.83 0.527 0.466 0.258 0.5881 1.69 0.679 4.23 PRS_PLINK_0.001 TRUE 367.9 Blindness and low vision Both 98 1479 7 sense organs darkseagreen4 1479, 98 370, 23 370, 28 369, 22 370, 25 0.0289 0.0839 0.73 0.1366 1.03 0.873 1.21 0.203 0.284 0.475 0.3236 1.22 0.703 2.14 -0.0142 0.298 0.962 0.01682 0.986 0.55 1.77 0.116 0.292 0.691 0.1608 1.12 0.633 1.99 PRS_PLINK_0.001 FALSE 368 Visual disturbances Both 523 6177 7 sense organs darkseagreen4 6177, 523 1545, 128 1544, 142 1544, 118 1544, 135 0.00773 0.042 0.854 0.06848 1.01 0.928 1.09 0.1 0.127 0.43 0.367 1.11 0.862 1.42 -0.0832 0.132 0.528 0.2772 0.92 0.711 1.19 0.05 0.128 0.696 0.1575 1.05 0.818 1.35 PRS_PLINK_0.001 FALSE 368.1 Amblyopia Both 89 1059 7 sense organs darkseagreen4 1059, 89 265, 21 265, 23 264, 22 265, 23 0.0603 0.12 0.614 0.2116 1.06 0.84 1.34 0.0654 0.306 0.831 0.08052 1.07 0.586 1.94 0.0436 0.309 0.888 0.05176 1.04 0.571 1.91 0.0596 0.305 0.845 0.07314 1.06 0.584 1.93 PRS_PLINK_0.001 FALSE 368.2 Diplopia and disorders of binocular vision Both 156 1583 7 sense organs darkseagreen4 1583, 156 396, 36 396, 38 395, 47 396, 35 0.0583 0.105 0.577 0.2389 1.06 0.864 1.3 0.0576 0.24 0.811 0.09114 1.06 0.661 1.7 0.253 0.23 0.272 0.566 1.29 0.82 2.02 -0.0122 0.244 0.96 0.01769 0.988 0.613 1.59 PRS_PLINK_0.001 FALSE 368.3 Anisometropia Both 34 323 7 sense organs darkseagreen4 323, 34 81, 11 81, 8 80, 5 81, 10 -0.454 0.609 0.456 0.3412 0.635 0.192 2.1 -0.371 0.468 0.428 0.369 0.69 0.276 1.73 -0.978 0.565 0.0834 1.079 0.376 0.124 1.14 -0.135 0.455 0.767 0.1151 0.874 0.358 2.13 PRS_PLINK_0.001 TRUE 368.4 Visual field defects Both 50 695 7 sense organs darkseagreen4 695, 50 174, 10 174, 10 173, 17 174, 13 0.187 0.463 0.686 0.1634 1.21 0.487 2.99 -0.0775 0.433 0.858 0.06649 0.925 0.396 2.16 0.435 0.396 0.273 0.5643 1.54 0.71 3.36 0.0616 0.418 0.883 0.05417 1.06 0.469 2.41 PRS_PLINK_0.001 TRUE 368.9 Subjective visual disturbances Both 88 1289 7 sense organs darkseagreen4 1289, 88 323, 22 322, 26 322, 16 322, 24 0.0667 0.0526 0.205 0.6877 1.07 0.964 1.19 0.123 0.293 0.673 0.1717 1.13 0.638 2.01 -0.372 0.327 0.255 0.5934 0.689 0.363 1.31 0.0317 0.298 0.915 0.03848 1.03 0.576 1.85 PRS_PLINK_0.001 FALSE 369 Infection of the eye Both 105 1116 7 sense organs darkseagreen4 1116, 105 279, 24 279, 32 279, 25 279, 24 0.0125 0.119 0.916 0.03802 1.01 0.802 1.28 0.293 0.279 0.293 0.5333 1.34 0.776 2.32 -0.0227 0.295 0.939 0.02741 0.978 0.548 1.74 0.0045 0.293 0.988 0.005356 1 0.566 1.78 PRS_PLINK_0.001 FALSE 369.2 Eye infection, viral Both 24 219 7 sense organs darkseagreen4 219, 24 55, 4 55, 11 54, 5 55, 4 -0.696 0.724 0.336 0.4734 0.499 0.121 2.06 0.853 0.577 0.139 0.8559 2.35 0.757 7.27 -0.08 0.643 0.901 0.04524 0.923 0.262 3.26 0.181 0.663 0.785 0.1051 1.2 0.327 4.4 PRS_PLINK_0.001 TRUE 369.5 Conjunctivitis, infectious Both 35 447 7 sense organs darkseagreen4 447, 35 112, 6 112, 13 111, 7 112, 9 -0.17 0.57 0.766 0.1159 0.844 0.276 2.58 0.786 0.484 0.104 0.981 2.2 0.85 5.67 0.283 0.555 0.61 0.2149 1.33 0.447 3.94 0.438 0.503 0.384 0.4156 1.55 0.578 4.15 PRS_PLINK_0.001 TRUE 370 Keratitis Both 50 589 7 sense organs darkseagreen4 589, 50 148, 15 147, 18 147, 13 147, 4 -1.17 0.455 0.0101 1.995 0.311 0.127 0.757 0.315 0.366 0.391 0.4083 1.37 0.668 2.81 -0.127 0.387 0.743 0.129 0.881 0.413 1.88 -1.14 0.543 0.0364 1.439 0.321 0.111 0.931 PRS_PLINK_0.001 TRUE 370.1 Corneal ulcer Both 24 300 7 sense organs darkseagreen4 300, 24 75, 6 75, 9 75, 8 75, 1 0.0273 0.0986 0.781 0.1071 1.03 0.847 1.25 0.711 0.565 0.209 0.6809 2.04 0.672 6.16 0.283 0.54 0.6 0.2218 1.33 0.461 3.82 -1.28 0.86 0.135 0.869 0.277 0.0513 1.49 PRS_PLINK_0.001 TRUE 371 Inflammation of the eye Both 672 6553 7 sense organs darkseagreen4 6553, 672 1639, 164 1638, 153 1638, 175 1638, 180 -0.0593 0.0545 0.276 0.5583 0.942 0.847 1.05 -0.0682 0.117 0.561 0.251 0.934 0.742 1.18 0.0634 0.114 0.578 0.2377 1.07 0.852 1.33 0.0928 0.113 0.412 0.3848 1.1 0.879 1.37 PRS_PLINK_0.001 FALSE 371.1 Uveitis, noninfectious or NOS Both 96 1022 7 sense organs darkseagreen4 1022, 96 256, 24 255, 17 255, 26 256, 29 -0.0188 0.0719 0.793 0.1005 0.981 0.852 1.13 -0.386 0.32 0.228 0.6427 0.68 0.363 1.27 0.0564 0.293 0.847 0.07196 1.06 0.596 1.88 0.202 0.287 0.481 0.3177 1.22 0.698 2.15 PRS_PLINK_0.001 FALSE 371.3 Inflammation of eyelids Both 517 5021 7 sense organs darkseagreen4 5021, 517 1256, 125 1255, 126 1255, 129 1255, 137 -0.047 0.0587 0.423 0.3739 0.954 0.85 1.07 0.0111 0.132 0.933 0.0301 1.01 0.781 1.31 0.032 0.131 0.807 0.09304 1.03 0.798 1.34 0.093 0.129 0.473 0.3254 1.1 0.851 1.41 PRS_PLINK_0.001 FALSE 372 Disorders of conjunctiva Both 134 1536 7 sense organs darkseagreen4 1536, 134 384, 33 384, 30 384, 48 384, 23 0.0153 0.104 0.883 0.05399 1.02 0.828 1.24 -0.106 0.258 0.683 0.1658 0.9 0.542 1.49 0.381 0.235 0.105 0.9793 1.46 0.924 2.32 -0.344 0.275 0.211 0.6755 0.709 0.413 1.22 PRS_PLINK_0.001 FALSE 374 Other disorders of eyelids Both 1069 11849 7 sense organs darkseagreen4 11849, 1069 2963, 252 2962, 316 2962, 255 2962, 246 0.0417 0.0237 0.0788 1.103 1.04 0.995 1.09 0.232 0.0883 0.00853 2.069 1.26 1.06 1.5 0.0184 0.0924 0.842 0.07459 1.02 0.85 1.22 -0.0144 0.0931 0.877 0.05704 0.986 0.821 1.18 PRS_PLINK_0.001 FALSE 374.1 Ectropion or entropion Both 168 2101 7 sense organs darkseagreen4 2101, 168 526, 38 525, 54 525, 42 525, 34 -0.00643 0.107 0.952 0.02133 0.994 0.806 1.23 0.325 0.218 0.137 0.8645 1.38 0.902 2.12 0.0844 0.228 0.711 0.1478 1.09 0.696 1.7 -0.116 0.24 0.629 0.2015 0.891 0.557 1.42 PRS_PLINK_0.001 FALSE 374.3 Ptosis of eyelid Both 373 3768 7 sense organs darkseagreen4 3768, 373 942, 97 942, 101 942, 97 942, 78 0.00508 0.0583 0.931 0.03123 1.01 0.897 1.13 0.0597 0.149 0.689 0.1621 1.06 0.793 1.42 0.00202 0.15 0.989 0.004697 1 0.747 1.34 -0.189 0.158 0.232 0.6346 0.827 0.607 1.13 PRS_PLINK_0.001 FALSE 375 Disorders of lacrimal system Both 411 4385 7 sense organs darkseagreen4 4385, 411 1096, 91 1096, 112 1096, 106 1096, 102 -0.0113 0.0596 0.85 0.0708 0.989 0.88 1.11 0.202 0.147 0.168 0.7754 1.22 0.918 1.63 0.147 0.148 0.322 0.4922 1.16 0.866 1.55 0.113 0.149 0.447 0.3494 1.12 0.836 1.5 PRS_PLINK_0.001 FALSE 375.2 Epiphora Both 159 1743 7 sense organs darkseagreen4 1743, 159 436, 33 436, 44 435, 36 436, 46 0.0299 0.0601 0.618 0.2089 1.03 0.916 1.16 0.305 0.236 0.196 0.7073 1.36 0.854 2.16 0.0731 0.246 0.766 0.1157 1.08 0.664 1.74 0.341 0.234 0.146 0.8364 1.41 0.888 2.23 PRS_PLINK_0.001 FALSE 376 Disorders of the orbit Both 9 178 7 sense organs darkseagreen4 178, 9 45, 0 44, 5 44, 2 45, 2 0.815 1.13 0.471 0.3272 2.26 0.247 20.7 1.93 1.16 0.0965 1.015 6.89 0.708 67 1.6 1.26 0.204 0.6913 4.95 0.421 58.2 0.686 1.21 0.572 0.2424 1.99 0.184 21.5 PRS_PLINK_0.001 TRUE 377 Disorders of optic nerve and visual pathways Both 65 790 7 sense organs darkseagreen4 790, 65 198, 15 197, 16 197, 17 198, 17 0.0595 0.115 0.606 0.2174 1.06 0.846 1.33 0.0063 0.36 0.986 0.006111 1.01 0.497 2.04 0.104 0.355 0.77 0.1138 1.11 0.553 2.23 0.101 0.357 0.776 0.1099 1.11 0.55 2.23 PRS_PLINK_0.001 FALSE 377.1 Optic atrophy Both 13 121 7 sense organs darkseagreen4 121, 13 31, 5 30, 2 30, 4 30, 2 -1.07 0.94 0.256 0.5925 0.343 0.0544 2.17 -2.04 1.13 0.072 1.142 0.13 0.014 1.2 -0.0872 0.681 0.898 0.04669 0.916 0.241 3.48 -0.808 0.776 0.297 0.5266 0.446 0.0974 2.04 PRS_PLINK_0.001 TRUE 377.3 Optic neuritis/neuropathy Both 22 294 7 sense organs darkseagreen4 294, 22 74, 2 73, 6 73, 7 74, 7 1.17 0.721 0.106 0.9765 3.21 0.782 13.2 0.93 0.707 0.188 0.7247 2.53 0.634 10.1 1.11 0.714 0.119 0.9256 3.05 0.752 12.3 1.28 0.718 0.0757 1.121 3.58 0.876 14.6 PRS_PLINK_0.001 TRUE 378 Strabismus and other disorders of binocular eye movements Both 264 3045 7 sense organs darkseagreen4 3045, 264 762, 71 761, 69 761, 66 761, 58 0.0625 0.0578 0.28 0.5532 1.06 0.95 1.19 -0.0226 0.175 0.897 0.04701 0.978 0.694 1.38 -0.0789 0.177 0.655 0.1836 0.924 0.654 1.31 -0.193 0.183 0.291 0.5361 0.825 0.576 1.18 PRS_PLINK_0.001 FALSE 378.1 Strabismus (not specified as paralytic) Both 170 2011 7 sense organs darkseagreen4 2011, 170 503, 43 503, 47 502, 46 503, 34 0.0691 0.0564 0.22 0.6578 1.07 0.96 1.2 0.093 0.218 0.669 0.1744 1.1 0.716 1.68 0.0668 0.219 0.76 0.1192 1.07 0.696 1.64 -0.214 0.234 0.361 0.4424 0.807 0.51 1.28 PRS_PLINK_0.001 FALSE 378.2 Nystagmus and other irregular eye movements Both 40 455 7 sense organs darkseagreen4 455, 40 114, 13 114, 8 113, 10 114, 9 -0.456 0.554 0.41 0.3868 0.634 0.214 1.88 -0.461 0.443 0.298 0.5255 0.631 0.265 1.5 -0.357 0.435 0.412 0.3851 0.7 0.298 1.64 -0.308 0.439 0.482 0.3165 0.735 0.311 1.74 PRS_PLINK_0.001 TRUE 378.5 Paralytic strabismus Both 54 586 7 sense organs darkseagreen4 586, 54 147, 14 146, 17 146, 8 147, 15 -0.486 0.454 0.284 0.546 0.615 0.252 1.5 0.0985 0.376 0.793 0.1006 1.1 0.528 2.31 -0.614 0.441 0.164 0.7854 0.541 0.228 1.28 0.0023 0.384 0.995 0.00208 1 0.472 2.13 PRS_PLINK_0.001 FALSE 379 Other disorders of eye Both 720 7504 7 sense organs darkseagreen4 7504, 720 1876, 211 1876, 159 1876, 179 1876, 171 -0.00834 0.0366 0.82 0.08632 0.992 0.923 1.07 -0.286 0.11 0.0092 2.036 0.752 0.606 0.932 -0.161 0.106 0.131 0.8838 0.851 0.691 1.05 -0.212 0.108 0.0484 1.315 0.809 0.655 0.998 PRS_PLINK_0.001 FALSE 379.2 Disorders of vitreous body Both 298 2895 7 sense organs darkseagreen4 2895, 298 724, 87 724, 66 723, 77 724, 68 0.0172 0.0479 0.719 0.1432 1.02 0.926 1.12 -0.28 0.17 0.1 0.9993 0.756 0.541 1.06 -0.128 0.164 0.434 0.363 0.88 0.638 1.21 -0.271 0.169 0.11 0.9596 0.763 0.547 1.06 PRS_PLINK_0.001 FALSE 379.3 Aphakia and other disorders of lens Both 319 3576 7 sense organs darkseagreen4 3576, 319 894, 83 894, 78 894, 74 894, 84 0.0324 0.0474 0.495 0.3058 1.03 0.941 1.13 -0.0572 0.163 0.726 0.1389 0.944 0.686 1.3 -0.105 0.166 0.529 0.2768 0.901 0.651 1.25 0.0127 0.16 0.937 0.02824 1.01 0.739 1.39 PRS_PLINK_0.001 FALSE 379.4 Anomalies of pupillary function Both 12 133 7 sense organs darkseagreen4 133, 12 34, 6 33, 0 33, 3 33, 3 -1.19 0.991 0.23 0.6377 0.305 0.0437 2.12 -2.1 1.17 0.0713 1.147 0.122 0.0124 1.2 -0.449 0.732 0.54 0.2679 0.638 0.152 2.68 -0.78 0.728 0.284 0.5459 0.459 0.11 1.91 PRS_PLINK_0.001 TRUE 379.5 Disorders of iris and ciliary body Both 64 879 7 sense organs darkseagreen4 879, 64 220, 16 220, 12 219, 24 220, 12 -0.0115 0.0854 0.893 0.04905 0.989 0.836 1.17 -0.316 0.385 0.412 0.3853 0.729 0.343 1.55 0.35 0.334 0.295 0.5306 1.42 0.737 2.73 -0.28 0.379 0.46 0.3369 0.756 0.359 1.59 PRS_PLINK_0.001 FALSE 379.9 Pain, swelling or discharge of eye Both 28 338 7 sense organs darkseagreen4 338, 28 85, 6 84, 7 84, 11 85, 4 0.0246 0.0715 0.731 0.1361 1.02 0.891 1.18 0.0817 0.539 0.88 0.05572 1.09 0.377 3.12 0.518 0.501 0.3 0.5222 1.68 0.629 4.48 -0.576 0.622 0.354 0.4506 0.562 0.166 1.9 PRS_PLINK_0.001 TRUE 380 Disorders of external ear Both 121 1330 7 sense organs darkseagreen4 1330, 121 333, 24 332, 33 332, 34 333, 30 -0.00182 0.0918 0.984 0.006914 0.998 0.834 1.19 0.324 0.274 0.236 0.6266 1.38 0.809 2.37 0.327 0.271 0.228 0.6421 1.39 0.815 2.36 0.213 0.277 0.441 0.3558 1.24 0.72 2.13 PRS_PLINK_0.001 FALSE 380.1 Otitis externa Both 87 1108 7 sense organs darkseagreen4 1108, 87 277, 16 277, 16 277, 27 277, 28 0.045 0.0677 0.506 0.2961 1.05 0.916 1.19 0.0377 0.349 0.914 0.03907 1.04 0.524 2.06 0.46 0.317 0.146 0.836 1.58 0.852 2.95 0.545 0.314 0.0823 1.084 1.73 0.932 3.19 PRS_PLINK_0.001 FALSE 380.4 Impacted cerumen Both 71 771 7 sense organs darkseagreen4 771, 71 193, 17 193, 10 192, 25 193, 19 0.086 0.105 0.411 0.3863 1.09 0.888 1.34 -0.581 0.394 0.141 0.8516 0.559 0.258 1.21 0.42 0.321 0.192 0.7176 1.52 0.81 2.86 0.111 0.338 0.743 0.1288 1.12 0.576 2.16 PRS_PLINK_0.001 FALSE 381 Otitis media and Eustachian tube disorders Both 380 4567 7 sense organs darkseagreen4 4567, 380 1142, 104 1142, 85 1141, 95 1142, 96 0.046 0.0341 0.178 0.7507 1.05 0.979 1.12 -0.192 0.151 0.204 0.6913 0.825 0.614 1.11 -0.0629 0.147 0.669 0.1743 0.939 0.703 1.25 -0.0783 0.147 0.593 0.2266 0.925 0.694 1.23 PRS_PLINK_0.001 FALSE 381.1 Otitis media Both 315 3778 7 sense organs darkseagreen4 3778, 315 945, 87 944, 65 944, 76 945, 87 0.052 0.035 0.138 0.8607 1.05 0.983 1.13 -0.272 0.169 0.107 0.9691 0.762 0.547 1.06 -0.0959 0.163 0.556 0.255 0.909 0.66 1.25 -0.00108 0.158 0.995 0.002392 0.999 0.734 1.36 PRS_PLINK_0.001 FALSE 381.11 Suppurative and unspecified otitis media Both 136 1829 7 sense organs darkseagreen4 1829, 136 458, 42 457, 28 457, 31 457, 35 -0.00802 0.0783 0.918 0.03698 0.992 0.851 1.16 -0.391 0.249 0.116 0.9368 0.676 0.415 1.1 -0.284 0.242 0.24 0.6203 0.753 0.469 1.21 -0.215 0.235 0.361 0.4425 0.807 0.509 1.28 PRS_PLINK_0.001 FALSE 381.2 Eustachian tube disorders Both 28 420 7 sense organs darkseagreen4 420, 28 105, 6 105, 6 105, 7 105, 9 0.123 0.0641 0.0552 1.258 1.13 0.997 1.28 -0.00373 0.528 0.994 0.002452 0.996 0.354 2.81 0.137 0.524 0.794 0.1003 1.15 0.411 3.2 0.327 0.503 0.517 0.2868 1.39 0.517 3.72 PRS_PLINK_0.001 TRUE 381.3 Mastoiditis & related conditions Both 23 338 7 sense organs darkseagreen4 338, 23 85, 8 84, 4 84, 5 85, 6 -0.308 0.69 0.656 0.1833 0.735 0.19 2.84 -0.588 0.577 0.308 0.5121 0.555 0.179 1.72 -0.458 0.554 0.408 0.3889 0.632 0.213 1.87 -0.146 0.52 0.779 0.1083 0.865 0.312 2.39 PRS_PLINK_0.001 TRUE 381.9 Otorrhea Both 48 566 7 sense organs darkseagreen4 566, 48 142, 18 141, 17 141, 10 142, 3 -1.14 0.479 0.0171 1.768 0.319 0.125 0.816 -0.0738 0.35 0.833 0.07941 0.929 0.468 1.84 -0.515 0.392 0.19 0.7218 0.598 0.277 1.29 -1.63 0.559 0.00351 2.455 0.195 0.0653 0.585 PRS_PLINK_0.001 TRUE 382 Otalgia Both 35 636 7 sense organs darkseagreen4 636, 35 159, 12 159, 9 159, 4 159, 10 -0.535 0.56 0.339 0.4698 0.586 0.195 1.75 -0.254 0.426 0.55 0.2594 0.776 0.337 1.79 -0.985 0.528 0.062 1.208 0.373 0.133 1.05 -0.168 0.415 0.685 0.1643 0.845 0.374 1.91 PRS_PLINK_0.001 TRUE 383 Otosclerosis Both 56 648 7 sense organs darkseagreen4 648, 56 162, 13 162, 13 162, 15 162, 15 0.137 0.0737 0.0638 1.195 1.15 0.992 1.32 -0.052 0.392 0.895 0.04835 0.949 0.44 2.05 0.13 0.383 0.735 0.1338 1.14 0.537 2.41 0.131 0.38 0.729 0.137 1.14 0.542 2.4 PRS_PLINK_0.001 FALSE 384 Other disorders of tympanic membrane Both 225 2784 7 sense organs darkseagreen4 2784, 225 696, 47 696, 54 696, 64 696, 60 0.035 0.0552 0.526 0.2788 1.04 0.929 1.15 0.135 0.204 0.509 0.2936 1.14 0.767 1.71 0.317 0.197 0.108 0.9673 1.37 0.933 2.02 0.248 0.2 0.214 0.6694 1.28 0.867 1.9 PRS_PLINK_0.001 FALSE 384.4 Perforation of tympanic membrane Both 168 2223 7 sense organs darkseagreen4 2223, 168 556, 36 556, 51 555, 37 556, 44 0.0432 0.0598 0.47 0.3281 1.04 0.929 1.17 0.337 0.224 0.132 0.8797 1.4 0.904 2.17 0.0614 0.237 0.796 0.09912 1.06 0.668 1.69 0.232 0.229 0.312 0.5053 1.26 0.804 1.98 PRS_PLINK_0.001 FALSE 385 Other disorders of middle ear and mastoid Both 142 1750 7 sense organs darkseagreen4 1750, 142 438, 29 437, 39 437, 42 438, 32 0.0339 0.084 0.686 0.1635 1.03 0.877 1.22 0.27 0.251 0.282 0.5495 1.31 0.801 2.14 0.367 0.246 0.136 0.8652 1.44 0.891 2.34 0.0679 0.26 0.794 0.1003 1.07 0.643 1.78 PRS_PLINK_0.001 FALSE 385.3 Cholesteatoma Both 108 1365 7 sense organs darkseagreen4 1365, 108 342, 24 341, 27 341, 30 341, 27 0.0512 0.0918 0.577 0.239 1.05 0.879 1.26 0.113 0.283 0.689 0.1615 1.12 0.643 1.95 0.259 0.279 0.353 0.4523 1.3 0.75 2.24 0.0905 0.284 0.75 0.1248 1.09 0.627 1.91 PRS_PLINK_0.001 FALSE 385.5 Tympanosclerosis and middle ear disease related to otitis media Both 38 515 7 sense organs darkseagreen4 515, 38 129, 7 129, 12 128, 13 129, 6 0.0383 0.104 0.713 0.1468 1.04 0.847 1.27 0.483 0.459 0.292 0.5342 1.62 0.66 3.98 0.507 0.451 0.261 0.5837 1.66 0.686 4.02 -0.197 0.512 0.7 0.1547 0.821 0.301 2.24 PRS_PLINK_0.001 TRUE 386 Vertiginous syndromes and other disorders of vestibular system Both 333 3679 7 sense organs darkseagreen4 3679, 333 920, 93 920, 78 919, 78 920, 84 0.00485 0.0464 0.917 0.03775 1 0.918 1.1 -0.177 0.16 0.268 0.5725 0.838 0.613 1.15 -0.158 0.16 0.323 0.4905 0.854 0.625 1.17 -0.0971 0.157 0.536 0.2707 0.907 0.667 1.23 PRS_PLINK_0.001 FALSE 386.1 Meniere's disease Both 112 1202 7 sense organs darkseagreen4 1202, 112 301, 37 300, 26 300, 27 301, 22 -0.85 0.35 0.0152 1.819 0.428 0.215 0.849 -0.352 0.264 0.184 0.736 0.704 0.419 1.18 -0.304 0.261 0.244 0.6122 0.738 0.443 1.23 -0.51 0.276 0.0644 1.191 0.6 0.35 1.03 PRS_PLINK_0.001 FALSE 386.2 Peripheral or central vertigo Both 77 774 7 sense organs darkseagreen4 774, 77 194, 21 193, 18 193, 15 194, 23 0.0296 0.094 0.753 0.1234 1.03 0.857 1.24 -0.026 0.337 0.938 0.02759 0.974 0.503 1.89 -0.297 0.345 0.389 0.4096 0.743 0.378 1.46 0.0656 0.312 0.834 0.07905 1.07 0.579 1.97 PRS_PLINK_0.001 FALSE 386.3 Labyrinthitis Both 138 1632 7 sense organs darkseagreen4 1632, 138 408, 37 408, 26 408, 37 408, 38 0.0407 0.0444 0.359 0.4447 1.04 0.955 1.14 -0.391 0.261 0.134 0.8718 0.676 0.405 1.13 0.0622 0.24 0.796 0.09917 1.06 0.664 1.7 0.051 0.239 0.831 0.08045 1.05 0.659 1.68 PRS_PLINK_0.001 FALSE 386.9 Dizziness and giddiness (Light-headedness and vertigo) Both 723 9495 7 sense organs darkseagreen4 9495, 723 2374, 182 2374, 158 2373, 190 2374, 193 0.0315 0.0331 0.341 0.4674 1.03 0.967 1.1 -0.146 0.112 0.192 0.7163 0.864 0.693 1.08 0.0456 0.107 0.671 0.173 1.05 0.848 1.29 0.0592 0.107 0.581 0.236 1.06 0.86 1.31 PRS_PLINK_0.001 FALSE 388 Other disorders of ear Both 45 447 7 sense organs darkseagreen4 447, 45 112, 9 112, 10 111, 8 112, 18 0.784 0.504 0.12 0.9204 2.19 0.815 5.88 0.171 0.453 0.706 0.1512 1.19 0.488 2.88 -0.115 0.479 0.811 0.091 0.892 0.349 2.28 0.58 0.414 0.161 0.7923 1.79 0.793 4.02 PRS_PLINK_0.001 TRUE 389 Hearing loss Both 793 8689 7 sense organs darkseagreen4 8689, 793 2173, 183 2172, 202 2172, 197 2172, 211 0.034 0.0322 0.291 0.5354 1.03 0.971 1.1 0.0984 0.106 0.354 0.4513 1.1 0.896 1.36 0.0733 0.107 0.492 0.308 1.08 0.873 1.33 0.137 0.105 0.192 0.7164 1.15 0.933 1.41 PRS_PLINK_0.001 FALSE 389.1 Sensorineural hearing loss Both 92 938 7 sense organs darkseagreen4 938, 92 235, 15 234, 26 234, 31 235, 20 -0.00125 0.0703 0.986 0.006201 0.999 0.87 1.15 0.495 0.328 0.131 0.8826 1.64 0.863 3.12 0.738 0.32 0.0213 1.673 2.09 1.12 3.92 0.276 0.343 0.42 0.3763 1.32 0.673 2.58 PRS_PLINK_0.001 FALSE 389.2 Conductive hearing loss Both 82 977 7 sense organs darkseagreen4 977, 82 245, 14 244, 25 244, 23 244, 20 0.0451 0.0788 0.568 0.2459 1.05 0.896 1.22 0.502 0.338 0.137 0.8635 1.65 0.852 3.2 0.466 0.342 0.173 0.7614 1.59 0.815 3.12 0.272 0.348 0.436 0.3607 1.31 0.663 2.6 PRS_PLINK_0.001 FALSE 389.4 Tinnitus Both 94 1053 7 sense organs darkseagreen4 1053, 94 264, 29 263, 23 263, 24 263, 18 -0.34 0.353 0.336 0.4741 0.712 0.356 1.42 -0.217 0.285 0.447 0.3494 0.805 0.46 1.41 -0.167 0.284 0.556 0.2551 0.846 0.485 1.48 -0.503 0.307 0.101 0.9944 0.605 0.331 1.1 PRS_PLINK_0.001 FALSE 394 Rheumatic disease of the heart valves Both 856 9990 8 circulatory system red 9990, 856 2498, 208 2497, 193 2497, 230 2498, 225 0.0237 0.0285 0.405 0.3924 1.02 0.968 1.08 -0.0779 0.104 0.452 0.3452 0.925 0.755 1.13 0.103 0.0995 0.299 0.5242 1.11 0.912 1.35 0.0714 0.1 0.476 0.3228 1.07 0.883 1.31 PRS_PLINK_0.001 FALSE 394.2 Mitral valve disease Both 534 6117 8 circulatory system red 6117, 534 1530, 126 1529, 121 1529, 148 1529, 139 0.0654 0.0311 0.0356 1.448 1.07 1 1.13 -0.038 0.132 0.773 0.1118 0.963 0.744 1.25 0.167 0.126 0.185 0.7338 1.18 0.923 1.51 0.099 0.128 0.438 0.359 1.1 0.86 1.42 PRS_PLINK_0.001 FALSE 394.3 Aortic valve disease Both 214 2613 8 circulatory system red 2613, 214 654, 53 653, 51 653, 49 653, 61 -0.00806 0.0769 0.917 0.03786 0.992 0.853 1.15 -0.068 0.202 0.736 0.133 0.934 0.629 1.39 -0.0781 0.204 0.701 0.154 0.925 0.621 1.38 0.0987 0.194 0.611 0.2136 1.1 0.754 1.62 PRS_PLINK_0.001 FALSE 394.7 Disease of tricuspid valve Both 181 2114 8 circulatory system red 2114, 181 529, 34 528, 45 528, 52 529, 50 0.0925 0.042 0.0274 1.562 1.1 1.01 1.19 0.287 0.232 0.216 0.6662 1.33 0.846 2.1 0.416 0.226 0.065 1.187 1.52 0.974 2.36 0.374 0.227 0.0987 1.006 1.45 0.932 2.27 PRS_PLINK_0.001 FALSE 395 Heart valve disorders Both 722 8662 8 circulatory system red 8662, 722 2166, 161 2165, 173 2165, 193 2166, 195 0.0579 0.0289 0.0452 1.345 1.06 1 1.12 0.0688 0.113 0.543 0.2652 1.07 0.858 1.34 0.185 0.111 0.0951 1.022 1.2 0.968 1.49 0.188 0.11 0.0875 1.058 1.21 0.973 1.5 PRS_PLINK_0.001 FALSE 395.1 Nonrheumatic mitral valve disorders Both 518 5907 8 circulatory system red 5907, 518 1477, 122 1477, 122 1476, 141 1477, 133 0.0634 0.0314 0.0433 1.363 1.07 1 1.13 0.00178 0.132 0.989 0.004691 1 0.773 1.3 0.147 0.128 0.251 0.6008 1.16 0.901 1.49 0.0848 0.13 0.514 0.2889 1.09 0.844 1.4 PRS_PLINK_0.001 FALSE 395.2 Nonrheumatic aortic valve disorders Both 39 553 8 circulatory system red 553, 39 139, 5 138, 7 138, 13 138, 14 0.12 0.126 0.34 0.4681 1.13 0.881 1.44 0.341 0.542 0.529 0.2765 1.41 0.486 4.07 0.732 0.495 0.139 0.856 2.08 0.788 5.49 0.977 0.488 0.0452 1.345 2.66 1.02 6.91 PRS_PLINK_0.001 TRUE 395.3 Nonrheumatic tricuspid valve disorders Both 18 229 8 circulatory system red 229, 18 58, 4 57, 8 57, 2 57, 4 -0.479 0.779 0.539 0.2688 0.619 0.135 2.85 0.964 0.643 0.134 0.8739 2.62 0.744 9.25 -0.508 0.884 0.565 0.2477 0.602 0.106 3.4 0.00822 0.691 0.991 0.004143 1.01 0.26 3.91 PRS_PLINK_0.001 TRUE 395.4 Nonrheumatic pulmonary valve disorders Both 14 179 8 circulatory system red 179, 14 45, 1 45, 3 44, 5 45, 5 1.97 0.917 0.0318 1.498 7.17 1.19 43.3 1.7 1.06 0.109 0.9639 5.5 0.685 44.1 1.22 0.821 0.137 0.8619 3.39 0.677 17 1.56 0.981 0.112 0.949 4.74 0.694 32.4 PRS_PLINK_0.001 TRUE 395.6 Heart valve replaced Both 253 3069 8 circulatory system red 3069, 253 768, 50 767, 63 767, 70 767, 70 0.0302 0.0594 0.611 0.2141 1.03 0.917 1.16 0.216 0.194 0.264 0.5779 1.24 0.849 1.81 0.336 0.19 0.0764 1.117 1.4 0.965 2.03 0.314 0.19 0.0985 1.006 1.37 0.943 1.99 PRS_PLINK_0.001 FALSE 396 Abnormal heart sounds Both 205 2230 8 circulatory system red 2230, 205 557, 52 557, 43 557, 54 558, 56 0.116 0.0683 0.0893 1.049 1.12 0.982 1.28 -0.174 0.212 0.412 0.3848 0.84 0.554 1.27 0.0422 0.201 0.834 0.07908 1.04 0.704 1.55 0.0819 0.2 0.682 0.1664 1.09 0.734 1.61 PRS_PLINK_0.001 FALSE 401 Hypertension Both 13351 59620 8 circulatory system red 59620, 13351 14904, 3317 14905, 3351 14905, 3259 14905, 3424 -0.000116 0.00949 0.99 0.004255 1 0.981 1.02 0.0186 0.028 0.507 0.2946 1.02 0.964 1.08 -0.0143 0.0282 0.611 0.2139 0.986 0.933 1.04 0.0428 0.0279 0.125 0.9029 1.04 0.988 1.1 PRS_PLINK_0.001 FALSE 401.1 Essential hypertension Both 13298 59584 8 circulatory system red 59584, 13298 14895, 3305 14896, 3334 14896, 3254 14896, 3405 -0.000168 0.0095 0.986 0.006155 1 0.981 1.02 0.0168 0.0281 0.549 0.2602 1.02 0.963 1.07 -0.013 0.0282 0.646 0.1895 0.987 0.934 1.04 0.0401 0.0279 0.151 0.8215 1.04 0.985 1.1 PRS_PLINK_0.001 FALSE 401.2 Hypertensive heart and/or renal disease Both 285 4032 8 circulatory system red 4032, 285 1008, 75 1008, 72 1008, 60 1008, 78 -0.0291 0.0795 0.714 0.1463 0.971 0.831 1.14 -0.0361 0.169 0.831 0.08051 0.965 0.692 1.34 -0.228 0.178 0.199 0.7015 0.796 0.562 1.13 0.018 0.167 0.914 0.0392 1.02 0.735 1.41 PRS_PLINK_0.001 FALSE 401.21 Hypertensive heart disease Both 58 813 8 circulatory system red 813, 58 204, 16 203, 15 203, 10 203, 17 0.0442 0.102 0.664 0.178 1.05 0.856 1.28 -0.0321 0.358 0.929 0.03215 0.968 0.48 1.95 -0.46 0.392 0.24 0.6192 0.631 0.293 1.36 -0.0204 0.356 0.954 0.0203 0.98 0.488 1.97 PRS_PLINK_0.001 FALSE 401.22 Hypertensive chronic kidney disease Both 229 3274 8 circulatory system red 3274, 229 819, 59 818, 59 818, 50 819, 61 -0.0158 0.0831 0.849 0.07114 0.984 0.836 1.16 0.0109 0.188 0.954 0.0205 1.01 0.699 1.46 -0.166 0.197 0.399 0.3988 0.847 0.576 1.25 0.0161 0.187 0.932 0.03073 1.02 0.704 1.47 PRS_PLINK_0.001 FALSE 401.3 Other hypertensive complications Both 22 301 8 circulatory system red 301, 22 76, 7 75, 7 75, 5 75, 3 -0.683 0.761 0.37 0.4317 0.505 0.114 2.25 0.254 0.542 0.639 0.1945 1.29 0.446 3.73 -0.018 0.587 0.975 0.01078 0.982 0.311 3.1 -0.52 0.649 0.423 0.374 0.594 0.167 2.12 PRS_PLINK_0.001 TRUE 402 Elevated blood pressure reading without diagnosis of hypertension Both 280 3161 8 circulatory system red 3161, 280 791, 74 790, 71 790, 60 790, 75 -0.0185 0.0722 0.798 0.09795 0.982 0.852 1.13 -0.0298 0.173 0.863 0.06412 0.971 0.692 1.36 -0.194 0.179 0.279 0.5541 0.824 0.58 1.17 0.0279 0.17 0.87 0.0605 1.03 0.736 1.44 PRS_PLINK_0.001 FALSE 411 Ischemic Heart Disease Both 5140 45135 8 circulatory system red 45135, 5140 11283, 1263 11284, 1248 11283, 1317 11284, 1312 0.00811 0.0134 0.545 0.2633 1.01 0.982 1.03 -0.0137 0.0424 0.746 0.1272 0.986 0.908 1.07 0.0395 0.0419 0.346 0.4605 1.04 0.958 1.13 0.0388 0.042 0.355 0.4492 1.04 0.957 1.13 PRS_PLINK_0.001 FALSE 411.1 Unstable angina (intermediate coronary syndrome) Both 864 10755 8 circulatory system red 10755, 864 2689, 212 2689, 213 2688, 206 2689, 233 -0.00512 0.0387 0.895 0.04836 0.995 0.922 1.07 0.00889 0.101 0.93 0.03173 1.01 0.828 1.23 -0.0255 0.101 0.801 0.09642 0.975 0.799 1.19 0.0918 0.0985 0.352 0.454 1.1 0.904 1.33 PRS_PLINK_0.001 FALSE 411.2 Myocardial infarction Both 1797 24245 8 circulatory system red 24245, 1797 6062, 463 6061, 437 6061, 423 6061, 474 0.0166 0.0215 0.438 0.3582 1.02 0.975 1.06 -0.0593 0.069 0.39 0.4086 0.942 0.823 1.08 -0.0904 0.0696 0.194 0.7119 0.914 0.797 1.05 0.0235 0.0677 0.728 0.1378 1.02 0.897 1.17 PRS_PLINK_0.001 FALSE 411.3 Angina pectoris Both 2545 30580 8 circulatory system red 30580, 2545 7645, 617 7645, 621 7645, 637 7645, 670 0.0224 0.0165 0.177 0.753 1.02 0.99 1.06 0.00638 0.0591 0.914 0.03903 1.01 0.896 1.13 0.0338 0.0588 0.565 0.2483 1.03 0.922 1.16 0.0866 0.0581 0.136 0.8655 1.09 0.973 1.22 PRS_PLINK_0.001 FALSE 411.4 Coronary atherosclerosis Both 3426 33278 8 circulatory system red 33278, 3426 8320, 875 8319, 817 8319, 877 8320, 857 0.00175 0.017 0.918 0.03716 1 0.969 1.04 -0.0704 0.0512 0.169 0.7713 0.932 0.843 1.03 0.00138 0.0504 0.978 0.009596 1 0.907 1.11 -0.0186 0.0507 0.714 0.1464 0.982 0.889 1.08 PRS_PLINK_0.001 FALSE 411.41 Aneurysm and dissection of heart Both 138 1493 8 circulatory system red 1493, 138 374, 27 373, 28 373, 34 373, 49 0.1 0.0426 0.0187 1.728 1.11 1.02 1.2 0.043 0.274 0.875 0.05792 1.04 0.611 1.79 0.225 0.262 0.39 0.4088 1.25 0.75 2.09 0.553 0.247 0.0254 1.595 1.74 1.07 2.82 PRS_PLINK_0.001 FALSE 411.8 Other chronic ischemic heart disease, unspecified Both 2290 28093 8 circulatory system red 28093, 2290 7024, 550 7023, 583 7023, 572 7023, 585 -0.0123 0.0234 0.598 0.2232 0.988 0.944 1.03 0.0553 0.0618 0.371 0.4305 1.06 0.936 1.19 0.0371 0.0621 0.551 0.2591 1.04 0.919 1.17 0.0621 0.0618 0.315 0.5015 1.06 0.943 1.2 PRS_PLINK_0.001 FALSE 411.9 Other acute and subacute forms of ischemic heart disease Both 208 2599 8 circulatory system red 2599, 208 650, 57 650, 56 649, 37 650, 58 0.0708 0.0576 0.219 0.6596 1.07 0.959 1.2 -0.0116 0.194 0.952 0.02125 0.988 0.676 1.44 -0.419 0.215 0.051 1.292 0.658 0.432 1 0.0227 0.192 0.906 0.04274 1.02 0.702 1.49 PRS_PLINK_0.001 FALSE 414 Other forms of chronic heart disease Both 293 3782 8 circulatory system red 3782, 293 946, 74 945, 81 945, 68 946, 70 -0.0525 0.0811 0.518 0.2858 0.949 0.809 1.11 0.0819 0.166 0.622 0.2061 1.09 0.784 1.5 -0.0734 0.173 0.671 0.1736 0.929 0.663 1.3 -0.06 0.172 0.727 0.1387 0.942 0.673 1.32 PRS_PLINK_0.001 FALSE 414.2 ASCVD Both 9 154 8 circulatory system red 154, 9 39, 1 38, 4 38, 3 39, 1 0.0626 1.01 0.951 0.02194 1.06 0.146 7.76 1.27 0.857 0.138 0.8587 3.56 0.664 19.1 0.836 0.899 0.352 0.4532 2.31 0.396 13.4 -0.0223 0.939 0.981 0.008313 0.978 0.155 6.16 PRS_PLINK_0.001 TRUE 415 Pulmonary heart disease Both 679 9261 8 circulatory system red 9261, 679 2316, 164 2315, 163 2315, 174 2315, 178 -0.00817 0.0384 0.832 0.08004 0.992 0.92 1.07 -0.0102 0.114 0.929 0.03219 0.99 0.792 1.24 0.0566 0.112 0.614 0.2117 1.06 0.849 1.32 0.079 0.112 0.48 0.3192 1.08 0.869 1.35 PRS_PLINK_0.001 FALSE 415.11 Pulmonary embolism and infarction, acute Both 7 132 8 circulatory system red 132, 7 33, 1 33, 4 33, 2 33, 0 -0.569 1.25 0.648 0.1886 0.566 0.0492 6.5 0.952 0.966 0.324 0.4895 2.59 0.391 17.2 0.702 1.04 0.502 0.2997 2.02 0.26 15.6 -0.558 1.23 0.65 0.1868 0.572 0.0512 6.4 PRS_PLINK_0.001 TRUE 415.2 Chronic pulmonary heart disease Both 90 1197 8 circulatory system red 1197, 90 300, 17 299, 19 299, 21 299, 33 0.0933 0.101 0.358 0.4464 1.1 0.9 1.34 0.0606 0.337 0.857 0.067 1.06 0.549 2.06 0.134 0.33 0.685 0.164 1.14 0.599 2.18 0.665 0.303 0.028 1.553 1.95 1.07 3.52 PRS_PLINK_0.001 FALSE 415.21 Primary pulmonary hypertension Both 76 878 8 circulatory system red 878, 76 220, 13 219, 16 219, 20 220, 27 0.033 0.0839 0.694 0.1585 1.03 0.877 1.22 0.114 0.375 0.762 0.1183 1.12 0.537 2.34 0.273 0.361 0.449 0.3478 1.31 0.648 2.66 0.741 0.34 0.0291 1.535 2.1 1.08 4.08 PRS_PLINK_0.001 FALSE 416 Cardiomegaly Both 417 5457 8 circulatory system red 5457, 417 1365, 99 1364, 92 1364, 112 1364, 114 -0.0124 0.0519 0.812 0.09068 0.988 0.892 1.09 -0.0647 0.149 0.664 0.178 0.937 0.7 1.25 0.128 0.142 0.368 0.4347 1.14 0.86 1.5 0.151 0.142 0.288 0.5405 1.16 0.88 1.54 PRS_PLINK_0.001 FALSE 418 Nonspecific chest pain Both 4926 58413 8 circulatory system red 58413, 4926 14603, 1238 14603, 1210 14603, 1199 14603, 1279 -0.0152 0.0163 0.35 0.4559 0.985 0.954 1.02 -0.0233 0.0421 0.579 0.237 0.977 0.9 1.06 -0.0331 0.0422 0.432 0.3642 0.967 0.891 1.05 0.0324 0.0415 0.435 0.3611 1.03 0.952 1.12 PRS_PLINK_0.001 FALSE 418.1 Precordial pain Both 599 7728 8 circulatory system red 7728, 599 1932, 160 1932, 139 1932, 137 1932, 163 0.0348 0.0281 0.215 0.6686 1.04 0.98 1.09 -0.135 0.12 0.259 0.5868 0.873 0.691 1.1 -0.155 0.12 0.197 0.7052 0.856 0.677 1.08 0.0189 0.115 0.87 0.06068 1.02 0.813 1.28 PRS_PLINK_0.001 FALSE 420 Carditis Both 380 4392 8 circulatory system red 4392, 380 1097, 112 1098, 90 1098, 86 1098, 92 -0.00279 0.0514 0.957 0.0192 0.997 0.902 1.1 -0.213 0.147 0.146 0.8351 0.808 0.606 1.08 -0.267 0.149 0.0721 1.142 0.766 0.572 1.02 -0.202 0.146 0.166 0.7801 0.817 0.613 1.09 PRS_PLINK_0.001 FALSE 420.1 Myocarditis Both 21 263 8 circulatory system red 263, 21 66, 4 66, 7 65, 4 66, 6 0.406 0.8 0.612 0.2134 1.5 0.313 7.2 0.62 0.614 0.312 0.5054 1.86 0.558 6.19 0.079 0.637 0.901 0.04518 1.08 0.311 3.77 0.073 0.607 0.904 0.04371 1.08 0.327 3.54 PRS_PLINK_0.001 TRUE 420.2 Pericarditis Both 253 2853 8 circulatory system red 2853, 253 714, 81 713, 59 713, 63 713, 50 0.0285 0.066 0.666 0.1764 1.03 0.904 1.17 -0.305 0.177 0.0854 1.068 0.737 0.521 1.04 -0.24 0.174 0.168 0.7744 0.786 0.559 1.11 -0.471 0.185 0.0111 1.955 0.624 0.434 0.898 PRS_PLINK_0.001 FALSE 420.21 Acute pericarditis Both 45 475 8 circulatory system red 475, 45 119, 9 119, 8 118, 9 119, 19 0.788 0.52 0.129 0.8883 2.2 0.794 6.09 -0.151 0.477 0.752 0.1237 0.86 0.338 2.19 -0.035 0.456 0.939 0.02737 0.966 0.395 2.36 0.624 0.411 0.129 0.8888 1.87 0.834 4.18 PRS_PLINK_0.001 TRUE 420.22 Chronic pericarditis Both 20 234 8 circulatory system red 234, 20 59, 7 58, 5 58, 5 59, 3 -0.928 0.768 0.226 0.645 0.395 0.0878 1.78 -0.407 0.572 0.477 0.3216 0.666 0.217 2.04 -0.102 0.589 0.862 0.06433 0.903 0.285 2.86 -0.819 0.696 0.24 0.6206 0.441 0.113 1.73 PRS_PLINK_0.001 TRUE 420.3 Endocarditis Both 122 1441 8 circulatory system red 1441, 122 360, 26 360, 34 360, 21 360, 41 0.0188 0.0702 0.789 0.103 1.02 0.888 1.17 0.25 0.266 0.349 0.4577 1.28 0.762 2.16 -0.212 0.294 0.47 0.3281 0.809 0.455 1.44 0.441 0.257 0.0857 1.067 1.55 0.94 2.57 PRS_PLINK_0.001 FALSE 425 Cardiomyopathy Both 221 2647 8 circulatory system red 2647, 221 662, 60 662, 59 661, 48 662, 54 -0.0187 0.0766 0.807 0.093 0.981 0.845 1.14 0.00203 0.19 0.991 0.003714 1 0.691 1.45 -0.204 0.2 0.307 0.5133 0.815 0.552 1.21 -0.0755 0.194 0.697 0.1567 0.927 0.634 1.36 PRS_PLINK_0.001 FALSE 425.1 Primary/intrinsic cardiomyopathies Both 219 2578 8 circulatory system red 2578, 219 645, 59 644, 57 644, 50 645, 53 -0.0163 0.0741 0.825 0.08331 0.984 0.851 1.14 -0.0109 0.193 0.955 0.02 0.989 0.678 1.44 -0.148 0.199 0.455 0.3418 0.862 0.584 1.27 -0.079 0.196 0.686 0.1636 0.924 0.63 1.36 PRS_PLINK_0.001 FALSE 425.11 Hypertrophic obstructive cardiomyopathy Both 33 269 8 circulatory system red 269, 33 68, 13 67, 9 67, 5 67, 6 -1.12 0.655 0.0882 1.054 0.327 0.0906 1.18 -0.227 0.47 0.629 0.2014 0.797 0.317 2 -0.646 0.542 0.233 0.6327 0.524 0.181 1.52 -0.756 0.534 0.157 0.804 0.469 0.165 1.34 PRS_PLINK_0.001 TRUE 425.12 Other hypertrophic cardiomyopathy Both 35 353 8 circulatory system red 353, 35 89, 11 88, 10 88, 9 88, 5 -0.791 0.584 0.175 0.756 0.453 0.144 1.42 -0.0679 0.46 0.883 0.05416 0.934 0.379 2.3 -0.142 0.457 0.757 0.1211 0.868 0.355 2.12 -0.684 0.522 0.19 0.721 0.505 0.181 1.4 PRS_PLINK_0.001 TRUE 425.8 Other cardiomyopathy Both 7 132 8 circulatory system red 132, 7 33, 2 33, 1 33, 1 33, 3 1.1 1.24 0.376 0.4251 2.99 0.265 33.7 -0.251 1.03 0.807 0.09321 0.778 0.104 5.84 0.657 1.15 0.569 0.2448 1.93 0.201 18.5 0.434 0.861 0.614 0.2116 1.54 0.285 8.34 PRS_PLINK_0.001 TRUE 426 Cardiac conduction disorders Both 1253 14093 8 circulatory system red 14093, 1253 3523, 336 3523, 295 3523, 297 3523, 325 0.0241 0.0223 0.279 0.5538 1.02 0.981 1.07 -0.132 0.0832 0.112 0.9515 0.876 0.744 1.03 -0.124 0.083 0.136 0.8656 0.884 0.751 1.04 -0.0349 0.0812 0.667 0.1757 0.966 0.824 1.13 PRS_PLINK_0.001 FALSE 426.2 Atrioventricular [AV] block Both 370 4288 8 circulatory system red 4288, 370 1072, 107 1072, 74 1072, 94 1072, 95 -0.0658 0.0771 0.394 0.4048 0.936 0.805 1.09 -0.363 0.156 0.0199 1.7 0.695 0.512 0.944 -0.139 0.147 0.346 0.4608 0.87 0.652 1.16 -0.1 0.147 0.494 0.3061 0.904 0.678 1.21 PRS_PLINK_0.001 FALSE 426.21 First degree AV block Both 174 1960 8 circulatory system red 1960, 174 490, 48 490, 37 490, 44 490, 45 -0.0253 0.0767 0.742 0.1298 0.975 0.839 1.13 -0.282 0.225 0.209 0.6789 0.754 0.486 1.17 -0.147 0.218 0.5 0.301 0.863 0.563 1.32 -0.0334 0.215 0.876 0.05726 0.967 0.635 1.47 PRS_PLINK_0.001 FALSE 426.23 Second degree AV block Both 97 906 8 circulatory system red 906, 97 227, 29 226, 20 226, 20 227, 28 0.0261 0.0981 0.79 0.1022 1.03 0.847 1.24 -0.354 0.3 0.239 0.6222 0.702 0.39 1.26 -0.377 0.302 0.213 0.6718 0.686 0.379 1.24 -0.0255 0.277 0.927 0.03309 0.975 0.566 1.68 PRS_PLINK_0.001 FALSE 426.24 Atrioventricular block, complete Both 93 1216 8 circulatory system red 1216, 93 304, 25 304, 25 304, 23 304, 20 -0.00511 0.0964 0.958 0.01877 0.995 0.824 1.2 -0.0317 0.291 0.913 0.0394 0.969 0.548 1.71 -0.114 0.293 0.696 0.1574 0.892 0.502 1.58 -0.221 0.304 0.468 0.3301 0.802 0.442 1.45 PRS_PLINK_0.001 FALSE 426.25 Other heart block Both 26 271 8 circulatory system red 271, 26 68, 5 68, 6 67, 10 68, 5 -0.109 0.599 0.856 0.06745 0.897 0.277 2.9 0.217 0.575 0.707 0.1509 1.24 0.402 3.83 0.794 0.575 0.167 0.7765 2.21 0.717 6.83 -0.515 0.737 0.485 0.3146 0.597 0.141 2.53 PRS_PLINK_0.001 TRUE 426.3 Bundle branch block Both 617 6782 8 circulatory system red 6782, 617 1696, 163 1695, 159 1695, 142 1696, 153 0.0312 0.0325 0.337 0.4718 1.03 0.968 1.1 -0.0192 0.116 0.869 0.06121 0.981 0.781 1.23 -0.136 0.119 0.255 0.5942 0.873 0.69 1.1 -0.0615 0.117 0.6 0.2217 0.94 0.747 1.18 PRS_PLINK_0.001 FALSE 426.31 Right bundle branch block Both 287 3076 8 circulatory system red 3076, 287 769, 88 769, 62 769, 63 769, 74 0.00975 0.0523 0.852 0.0695 1.01 0.911 1.12 -0.34 0.172 0.048 1.319 0.712 0.508 0.997 -0.348 0.172 0.0424 1.373 0.706 0.504 0.988 -0.17 0.164 0.303 0.5192 0.844 0.611 1.17 PRS_PLINK_0.001 FALSE 426.32 Left bundle branch block Both 324 3538 8 circulatory system red 3538, 324 885, 76 884, 95 884, 77 885, 76 0.0596 0.0411 0.147 0.8326 1.06 0.979 1.15 0.23 0.16 0.151 0.8198 1.26 0.919 1.72 0.0407 0.168 0.808 0.0925 1.04 0.75 1.45 0.00301 0.168 0.986 0.00627 1 0.722 1.39 PRS_PLINK_0.001 FALSE 426.4 Anomalous atrioventricular excitation Both 55 538 8 circulatory system red 538, 55 135, 12 134, 13 134, 14 135, 16 0.405 0.474 0.393 0.4051 1.5 0.592 3.8 0.151 0.403 0.708 0.15 1.16 0.528 2.56 0.152 0.397 0.703 0.1532 1.16 0.534 2.54 0.172 0.387 0.657 0.1821 1.19 0.556 2.53 PRS_PLINK_0.001 FALSE 426.8 Other cardiac conduction disorders Both 8 126 8 circulatory system red 126, 8 32, 1 31, 2 31, 4 32, 1 1.18 0.956 0.216 0.6656 3.26 0.501 21.2 0.755 1.06 0.477 0.3214 2.13 0.265 17.1 1.59 1.1 0.147 0.8317 4.9 0.571 42 0.304 1.13 0.787 0.1038 1.36 0.149 12.3 PRS_PLINK_0.001 TRUE 426.9 Cardiac pacemaker/device in situ Both 404 5015 8 circulatory system red 5015, 404 1254, 103 1254, 99 1253, 93 1254, 109 0.00771 0.0422 0.855 0.068 1.01 0.928 1.09 -0.0349 0.146 0.811 0.09107 0.966 0.726 1.28 -0.0904 0.148 0.54 0.2676 0.914 0.684 1.22 0.063 0.142 0.658 0.182 1.07 0.806 1.41 PRS_PLINK_0.001 FALSE 426.91 Cardiac pacemaker in situ Both 383 4604 8 circulatory system red 4604, 383 1151, 97 1151, 96 1151, 86 1151, 104 0.00597 0.0428 0.889 0.05098 1.01 0.925 1.09 -0.00319 0.149 0.983 0.007477 0.997 0.744 1.34 -0.113 0.153 0.461 0.336 0.894 0.662 1.21 0.0747 0.146 0.609 0.2151 1.08 0.809 1.44 PRS_PLINK_0.001 FALSE 427 Cardiac dysrhythmias Both 4311 43689 8 circulatory system red 43689, 4311 10923, 1090 10922, 1037 10922, 1087 10922, 1097 -0.00233 0.016 0.885 0.05327 0.998 0.967 1.03 -0.05 0.0455 0.272 0.5653 0.951 0.87 1.04 -0.00435 0.045 0.923 0.03482 0.996 0.912 1.09 0.00433 0.0449 0.923 0.03468 1 0.92 1.1 PRS_PLINK_0.001 FALSE 427.1 Paroxysmal tachycardia, unspecified Both 582 6812 8 circulatory system red 6812, 582 1703, 137 1703, 143 1703, 149 1703, 153 0.0394 0.0303 0.193 0.7142 1.04 0.98 1.1 0.0411 0.124 0.74 0.1308 1.04 0.818 1.33 0.0827 0.123 0.5 0.3006 1.09 0.854 1.38 0.111 0.122 0.363 0.4396 1.12 0.88 1.42 PRS_PLINK_0.001 FALSE 427.11 Paroxysmal supraventricular tachycardia Both 426 4954 8 circulatory system red 4954, 426 1239, 100 1238, 105 1238, 109 1239, 112 0.0488 0.0315 0.121 0.9155 1.05 0.987 1.12 0.0462 0.144 0.749 0.1256 1.05 0.789 1.39 0.0791 0.143 0.581 0.2355 1.08 0.817 1.43 0.112 0.142 0.433 0.3636 1.12 0.846 1.48 PRS_PLINK_0.001 FALSE 427.12 Paroxysmal ventricular tachycardia Both 171 2048 8 circulatory system red 2048, 171 512, 39 512, 46 512, 41 512, 45 0.0167 0.0812 0.837 0.07703 1.02 0.867 1.19 0.151 0.224 0.5 0.301 1.16 0.75 1.8 0.0678 0.229 0.768 0.1149 1.07 0.683 1.68 0.12 0.224 0.593 0.2272 1.13 0.727 1.75 PRS_PLINK_0.001 FALSE 427.2 Atrial fibrillation and flutter Both 2584 27809 8 circulatory system red 27809, 2584 6953, 648 6952, 641 6952, 643 6952, 652 -0.0313 0.026 0.228 0.6417 0.969 0.921 1.02 -0.0138 0.0582 0.813 0.09006 0.986 0.88 1.11 -0.00897 0.0582 0.877 0.05676 0.991 0.884 1.11 0.00326 0.058 0.955 0.01989 1 0.895 1.12 PRS_PLINK_0.001 FALSE 427.3 Other specified cardiac dysrhythmias Both 581 6722 8 circulatory system red 6722, 581 1681, 156 1680, 127 1680, 140 1681, 158 0.0401 0.0295 0.174 0.7592 1.04 0.982 1.1 -0.201 0.124 0.104 0.9825 0.818 0.642 1.04 -0.0988 0.121 0.414 0.3827 0.906 0.715 1.15 0.0209 0.118 0.859 0.06612 1.02 0.811 1.29 PRS_PLINK_0.001 FALSE 427.4 Cardiac arrest and ventricular fibrillation Both 183 2538 8 circulatory system red 2538, 183 635, 52 634, 32 634, 47 635, 52 0.0115 0.0673 0.864 0.06345 1.01 0.887 1.15 -0.481 0.227 0.0345 1.462 0.618 0.396 0.966 -0.0932 0.206 0.651 0.1865 0.911 0.608 1.36 -0.0239 0.202 0.906 0.04299 0.976 0.657 1.45 PRS_PLINK_0.001 FALSE 427.41 Ventricular fibrillation and flutter Both 63 780 8 circulatory system red 780, 63 195, 20 195, 12 195, 17 195, 14 0.0529 0.102 0.602 0.2202 1.05 0.864 1.29 -0.491 0.367 0.181 0.7416 0.612 0.298 1.26 -0.128 0.336 0.703 0.153 0.88 0.455 1.7 -0.365 0.351 0.298 0.5261 0.694 0.349 1.38 PRS_PLINK_0.001 FALSE 427.42 Cardiac arrest Both 149 2061 8 circulatory system red 2061, 149 516, 42 515, 31 515, 36 515, 40 0.017 0.0956 0.859 0.06622 1.02 0.843 1.23 -0.327 0.241 0.173 0.7609 0.721 0.45 1.15 -0.156 0.231 0.5 0.3015 0.855 0.544 1.35 -0.0734 0.226 0.746 0.1275 0.929 0.596 1.45 PRS_PLINK_0.001 FALSE 427.5 Arrhythmia (cardiac) NOS Both 175 1989 8 circulatory system red 1989, 175 498, 42 497, 41 497, 42 497, 50 0.0393 0.046 0.393 0.4061 1.04 0.95 1.14 -0.0271 0.226 0.905 0.04349 0.973 0.625 1.52 0.0128 0.225 0.955 0.02012 1.01 0.652 1.57 0.158 0.216 0.464 0.3333 1.17 0.767 1.79 PRS_PLINK_0.001 FALSE 427.6 Premature beats Both 106 1163 8 circulatory system red 1163, 106 291, 27 291, 25 290, 21 291, 33 0.0479 0.0509 0.347 0.4599 1.05 0.949 1.16 -0.0683 0.282 0.809 0.09223 0.934 0.537 1.62 -0.236 0.294 0.423 0.374 0.79 0.444 1.41 0.202 0.269 0.452 0.3445 1.22 0.723 2.07 PRS_PLINK_0.001 FALSE 427.61 Supraventricular premature beats Both 23 225 8 circulatory system red 225, 23 57, 4 56, 6 56, 6 56, 7 0.514 0.614 0.403 0.3947 1.67 0.501 5.57 0.516 0.631 0.413 0.3836 1.68 0.486 5.77 0.382 0.602 0.526 0.279 1.46 0.45 4.77 0.615 0.621 0.322 0.4922 1.85 0.548 6.24 PRS_PLINK_0.001 TRUE 427.7 Tachycardia NOS Both 337 4592 8 circulatory system red 4592, 337 1148, 81 1148, 77 1148, 98 1148, 81 0.0527 0.0319 0.099 1.004 1.05 0.99 1.12 -0.0562 0.163 0.731 0.136 0.945 0.686 1.3 0.178 0.155 0.25 0.6026 1.2 0.882 1.62 -0.0186 0.161 0.908 0.04186 0.982 0.715 1.35 PRS_PLINK_0.001 FALSE 427.8 Sinoatrial node dysfunction (Bradycardia) Both 71 807 8 circulatory system red 807, 71 202, 13 202, 16 201, 21 202, 21 0.133 0.0745 0.0739 1.131 1.14 0.987 1.32 0.173 0.37 0.64 0.1936 1.19 0.576 2.45 0.429 0.356 0.228 0.6418 1.53 0.765 3.08 0.439 0.354 0.214 0.6688 1.55 0.776 3.1 PRS_PLINK_0.001 FALSE 427.9 Palpitations Both 714 8094 8 circulatory system red 8094, 714 2024, 166 2023, 189 2023, 178 2024, 181 0.00174 0.0422 0.967 0.01449 1 0.922 1.09 0.126 0.111 0.256 0.5921 1.13 0.913 1.41 0.0666 0.112 0.552 0.2583 1.07 0.858 1.33 0.0844 0.112 0.45 0.3472 1.09 0.874 1.35 PRS_PLINK_0.001 FALSE 428 Congestive heart failure; nonhypertensive Both 811 11409 8 circulatory system red 11409, 811 2853, 202 2852, 179 2852, 220 2852, 210 -0.0467 0.0515 0.365 0.4381 0.954 0.863 1.06 -0.122 0.106 0.248 0.6055 0.885 0.72 1.09 0.089 0.101 0.376 0.4243 1.09 0.897 1.33 0.0455 0.102 0.655 0.1838 1.05 0.857 1.28 PRS_PLINK_0.001 FALSE 428.1 Congestive heart failure (CHF) NOS Both 283 4297 8 circulatory system red 4297, 283 1075, 74 1074, 67 1074, 78 1074, 64 -0.0681 0.0945 0.471 0.3266 0.934 0.776 1.12 -0.101 0.172 0.557 0.254 0.904 0.645 1.27 0.0464 0.166 0.78 0.1076 1.05 0.756 1.45 -0.141 0.174 0.418 0.3787 0.868 0.617 1.22 PRS_PLINK_0.001 FALSE 428.2 Heart failure NOS Both 650 9051 8 circulatory system red 9051, 650 2263, 152 2263, 141 2262, 172 2263, 185 -0.000433 0.0454 0.992 0.003315 1 0.914 1.09 -0.0738 0.12 0.539 0.2687 0.929 0.734 1.18 0.13 0.115 0.258 0.5876 1.14 0.909 1.43 0.204 0.113 0.0704 1.152 1.23 0.983 1.53 PRS_PLINK_0.001 FALSE 429 Ill-defined descriptions and complications of heart disease Both 147 1484 8 circulatory system red 1484, 147 371, 35 371, 34 371, 39 371, 39 0.0286 0.0643 0.657 0.1823 1.03 0.907 1.17 -0.0548 0.248 0.825 0.08343 0.947 0.582 1.54 0.116 0.241 0.629 0.2013 1.12 0.701 1.8 0.0989 0.241 0.681 0.1668 1.1 0.689 1.77 PRS_PLINK_0.001 FALSE 429.1 Heart transplant/surgery Both 15 148 8 circulatory system red 148, 15 37, 5 37, 1 37, 4 37, 5 0.0439 0.778 0.955 0.02 1.04 0.227 4.8 -0.978 0.868 0.26 0.5845 0.376 0.0686 2.06 -0.204 0.718 0.776 0.1102 0.815 0.199 3.33 -0.0587 0.646 0.928 0.0326 0.943 0.266 3.35 PRS_PLINK_0.001 TRUE 429.2 Abnormal function study of cardiovascular system Both 107 1060 8 circulatory system red 1060, 107 265, 23 265, 26 265, 29 265, 29 0.0263 0.0639 0.68 0.1672 1.03 0.906 1.16 0.109 0.293 0.709 0.1492 1.12 0.628 1.98 0.252 0.287 0.38 0.4204 1.29 0.733 2.26 0.224 0.288 0.436 0.3604 1.25 0.712 2.2 PRS_PLINK_0.001 FALSE 429.3 Symptoms involving cardiovascular system Both 40 437 8 circulatory system red 437, 40 110, 10 109, 10 109, 11 109, 9 -0.0736 0.528 0.889 0.05103 0.929 0.33 2.62 0.0188 0.442 0.966 0.01502 1.02 0.429 2.42 0.039 0.436 0.929 0.03212 1.04 0.442 2.44 -0.178 0.453 0.695 0.1579 0.837 0.344 2.04 PRS_PLINK_0.001 TRUE 430 Intracranial hemorrhage Both 308 3830 8 circulatory system red 3830, 308 958, 85 957, 88 957, 60 958, 75 -0.288 0.192 0.133 0.8758 0.75 0.515 1.09 0.0407 0.158 0.796 0.09905 1.04 0.765 1.42 -0.347 0.173 0.0445 1.351 0.707 0.504 0.992 -0.134 0.164 0.413 0.3841 0.875 0.635 1.21 PRS_PLINK_0.001 FALSE 430.1 Subarachnoid hemorrhage Both 154 1753 8 circulatory system red 1753, 154 439, 47 438, 40 438, 31 438, 36 -0.509 0.282 0.0711 1.148 0.601 0.346 1.04 -0.163 0.223 0.465 0.3329 0.85 0.549 1.31 -0.411 0.236 0.0822 1.085 0.663 0.417 1.05 -0.26 0.228 0.255 0.5939 0.771 0.493 1.21 PRS_PLINK_0.001 FALSE 430.2 Intracerebral hemorrhage Both 107 1536 8 circulatory system red 1536, 107 384, 23 384, 31 384, 21 384, 32 0.0357 0.0658 0.588 0.2309 1.04 0.911 1.18 0.273 0.278 0.327 0.4859 1.31 0.762 2.27 -0.0778 0.3 0.796 0.09934 0.925 0.514 1.67 0.328 0.277 0.236 0.6273 1.39 0.807 2.39 PRS_PLINK_0.001 FALSE 430.3 Subdural hemorrhage Both 47 492 8 circulatory system red 492, 47 123, 15 123, 15 123, 9 123, 8 -0.77 0.529 0.146 0.8359 0.463 0.164 1.31 -0.0925 0.382 0.809 0.09218 0.912 0.431 1.93 -0.542 0.419 0.196 0.7084 0.581 0.256 1.32 -0.705 0.435 0.105 0.9779 0.494 0.21 1.16 PRS_PLINK_0.001 TRUE 433 Cerebrovascular disease Both 1246 17845 8 circulatory system red 17845, 1246 4462, 323 4461, 314 4461, 292 4461, 317 0.0185 0.024 0.441 0.3558 1.02 0.972 1.07 -0.033 0.0819 0.687 0.1629 0.968 0.824 1.14 -0.102 0.0833 0.219 0.6591 0.903 0.767 1.06 -0.0192 0.0817 0.814 0.08951 0.981 0.836 1.15 PRS_PLINK_0.001 FALSE 433.1 Occlusion and stenosis of precerebral arteries Both 147 2356 8 circulatory system red 2356, 147 589, 39 589, 36 589, 33 589, 39 0.0728 0.0401 0.0695 1.158 1.08 0.994 1.16 -0.0824 0.235 0.725 0.1395 0.921 0.581 1.46 -0.151 0.239 0.529 0.2763 0.86 0.538 1.37 -0.0264 0.23 0.909 0.04158 0.974 0.62 1.53 PRS_PLINK_0.001 FALSE 433.12 Cerebral atherosclerosis Both 25 415 8 circulatory system red 415, 25 104, 8 104, 7 103, 5 104, 5 0.118 0.0723 0.103 0.9878 1.13 0.977 1.3 -0.291 0.509 0.567 0.2461 0.747 0.276 2.03 -0.183 0.544 0.736 0.133 0.833 0.287 2.42 -0.395 0.536 0.461 0.3364 0.674 0.236 1.93 PRS_PLINK_0.001 TRUE 433.2 Occlusion of cerebral arteries Both 582 8588 8 circulatory system red 8588, 582 2147, 147 2147, 146 2147, 135 2147, 154 -0.0399 0.068 0.557 0.2542 0.961 0.841 1.1 -0.00927 0.12 0.939 0.02752 0.991 0.783 1.25 -0.0818 0.123 0.504 0.2975 0.921 0.725 1.17 0.0366 0.119 0.758 0.1202 1.04 0.822 1.31 PRS_PLINK_0.001 FALSE 433.21 Cerebral artery occlusion, with cerebral infarction Both 201 3419 8 circulatory system red 3419, 201 855, 59 855, 54 854, 43 855, 45 -0.00629 0.13 0.961 0.01711 0.994 0.77 1.28 -0.0754 0.192 0.695 0.1583 0.927 0.636 1.35 -0.303 0.203 0.136 0.8654 0.739 0.496 1.1 -0.276 0.201 0.17 0.7699 0.759 0.511 1.13 PRS_PLINK_0.001 FALSE 433.3 Cerebral ischemia Both 413 5853 8 circulatory system red 5853, 413 1464, 101 1463, 107 1463, 98 1463, 107 0.0156 0.0435 0.72 0.1424 1.02 0.933 1.11 0.0549 0.143 0.7 0.1547 1.06 0.799 1.4 -0.0179 0.146 0.902 0.04471 0.982 0.738 1.31 0.0735 0.143 0.607 0.2169 1.08 0.813 1.42 PRS_PLINK_0.001 FALSE 433.31 Transient cerebral ischemia Both 326 4252 8 circulatory system red 4252, 326 1063, 82 1063, 80 1063, 74 1063, 90 0.0312 0.0444 0.483 0.316 1.03 0.946 1.13 -0.0318 0.162 0.844 0.07365 0.969 0.706 1.33 -0.115 0.165 0.485 0.3141 0.891 0.645 1.23 0.113 0.158 0.476 0.3223 1.12 0.821 1.53 PRS_PLINK_0.001 FALSE 433.5 Cerebral aneurysm Both 45 848 8 circulatory system red 848, 45 212, 13 212, 15 212, 10 212, 7 -0.502 0.487 0.302 0.5194 0.605 0.233 1.57 0.176 0.374 0.639 0.1947 1.19 0.572 2.48 -0.287 0.404 0.477 0.3211 0.751 0.34 1.66 -0.677 0.455 0.137 0.8629 0.508 0.208 1.24 PRS_PLINK_0.001 TRUE 433.8 Late effects of cerebrovascular disease Both 157 2577 8 circulatory system red 2577, 157 645, 41 644, 39 644, 35 644, 42 0.0111 0.0868 0.899 0.04638 1.01 0.853 1.2 -0.0857 0.227 0.706 0.1513 0.918 0.588 1.43 -0.16 0.232 0.491 0.3088 0.852 0.541 1.34 0.0242 0.223 0.914 0.03915 1.02 0.661 1.59 PRS_PLINK_0.001 FALSE 440 Atherosclerosis Both 209 2789 8 circulatory system red 2789, 209 698, 57 697, 55 697, 41 697, 56 0.093 0.0626 0.137 0.862 1.1 0.971 1.24 -0.0393 0.195 0.84 0.07554 0.962 0.656 1.41 -0.295 0.209 0.158 0.802 0.744 0.494 1.12 -0.00588 0.194 0.976 0.01062 0.994 0.679 1.45 PRS_PLINK_0.001 FALSE 440.1 Atherosclerosis of renal artery Both 21 238 8 circulatory system red 238, 21 60, 7 59, 5 59, 1 60, 8 0.122 0.695 0.86 0.06544 1.13 0.29 4.41 -0.442 0.606 0.466 0.3317 0.643 0.196 2.11 -1.6 0.811 0.0493 1.307 0.203 0.0414 0.995 0.0834 0.524 0.874 0.05869 1.09 0.389 3.03 PRS_PLINK_0.001 TRUE 440.2 Atherosclerosis of the extremities Both 119 1617 8 circulatory system red 1617, 119 405, 34 404, 30 404, 27 404, 28 0.099 0.0643 0.124 0.9081 1.1 0.973 1.25 -0.111 0.255 0.664 0.1777 0.895 0.543 1.47 -0.217 0.263 0.41 0.3869 0.805 0.481 1.35 -0.151 0.26 0.562 0.2503 0.86 0.517 1.43 PRS_PLINK_0.001 FALSE 440.9 Atherosclerosis of aorta Both 42 571 8 circulatory system red 571, 42 143, 8 143, 16 142, 7 143, 11 0.0616 0.522 0.906 0.04288 1.06 0.382 2.96 0.659 0.434 0.129 0.8891 1.93 0.825 4.52 -0.0801 0.492 0.871 0.06011 0.923 0.352 2.42 0.438 0.462 0.343 0.4651 1.55 0.627 3.83 PRS_PLINK_0.001 TRUE 441 Vascular insufficiency of intestine Both 100 1252 8 circulatory system red 1252, 100 313, 24 313, 22 313, 26 313, 28 0.02 0.0852 0.815 0.08906 1.02 0.863 1.21 -0.0443 0.298 0.882 0.05467 0.957 0.534 1.72 0.0884 0.287 0.758 0.1201 1.09 0.622 1.92 0.178 0.284 0.531 0.275 1.19 0.685 2.08 PRS_PLINK_0.001 FALSE 441.1 Acute vascular insufficiency of intestine Both 53 573 8 circulatory system red 573, 53 144, 11 143, 16 143, 9 143, 17 0.0368 0.0872 0.673 0.1722 1.04 0.874 1.23 0.407 0.395 0.303 0.5184 1.5 0.692 3.26 -0.204 0.435 0.64 0.1938 0.816 0.348 1.91 0.446 0.391 0.254 0.5948 1.56 0.726 3.36 PRS_PLINK_0.001 FALSE 442 Other aneurysm Both 318 3853 8 circulatory system red 3853, 318 964, 78 963, 75 963, 82 963, 83 0.0438 0.0416 0.292 0.5349 1.04 0.963 1.13 -0.0392 0.167 0.814 0.0895 0.962 0.694 1.33 0.0404 0.164 0.805 0.09428 1.04 0.756 1.44 0.0612 0.163 0.707 0.1505 1.06 0.773 1.46 PRS_PLINK_0.001 FALSE 442.1 Aortic aneurysm Both 241 2934 8 circulatory system red 2934, 241 734, 59 733, 53 733, 66 734, 63 0.0499 0.0441 0.258 0.5879 1.05 0.964 1.15 -0.11 0.194 0.572 0.2428 0.896 0.613 1.31 0.106 0.185 0.567 0.2465 1.11 0.774 1.6 0.0628 0.187 0.736 0.133 1.06 0.739 1.53 PRS_PLINK_0.001 FALSE 442.11 Abdominal aortic aneurysm Both 143 1818 8 circulatory system red 1818, 143 455, 39 454, 35 454, 34 455, 35 0.051 0.047 0.279 0.5551 1.05 0.96 1.15 -0.118 0.238 0.62 0.2076 0.888 0.557 1.42 -0.189 0.242 0.433 0.3631 0.828 0.515 1.33 -0.106 0.239 0.656 0.1829 0.899 0.563 1.44 PRS_PLINK_0.001 FALSE 442.2 Aneurysm of iliac artery Both 15 179 8 circulatory system red 179, 15 45, 5 45, 1 44, 3 45, 6 0.0213 0.0674 0.753 0.1234 1.02 0.895 1.17 -0.976 0.823 0.236 0.6279 0.377 0.0752 1.89 -0.406 0.672 0.545 0.2633 0.666 0.179 2.49 0.218 0.61 0.721 0.1419 1.24 0.376 4.11 PRS_PLINK_0.001 TRUE 442.3 Aneurysm of artery of lower extremity Both 34 339 8 circulatory system red 339, 34 85, 5 85, 13 84, 6 85, 10 0.629 0.61 0.303 0.519 1.88 0.567 6.2 0.808 0.522 0.122 0.9138 2.24 0.806 6.24 0.357 0.585 0.542 0.2656 1.43 0.454 4.5 0.791 0.555 0.155 0.8108 2.2 0.742 6.55 PRS_PLINK_0.001 TRUE 442.4 Arterial dissection Both 14 118 8 circulatory system red 118, 14 30, 4 29, 4 29, 4 30, 2 -1 0.99 0.312 0.5055 0.368 0.0529 2.56 0.284 0.838 0.735 0.1339 1.33 0.257 6.86 -0.195 0.777 0.802 0.09605 0.823 0.179 3.77 -0.496 0.816 0.543 0.265 0.609 0.123 3.01 PRS_PLINK_0.001 TRUE 442.8 Aneurysm of other specified artery Both 25 451 8 circulatory system red 451, 25 113, 11 113, 3 112, 7 113, 4 -0.729 0.654 0.265 0.5764 0.482 0.134 1.74 -0.979 0.6 0.103 0.989 0.376 0.116 1.22 -0.38 0.474 0.422 0.3744 0.684 0.27 1.73 -0.87 0.546 0.111 0.9542 0.419 0.144 1.22 PRS_PLINK_0.001 TRUE 443 Peripheral vascular disease Both 574 7992 8 circulatory system red 7992, 574 1998, 129 1998, 152 1998, 157 1998, 136 0.0297 0.0373 0.426 0.371 1.03 0.958 1.11 0.154 0.123 0.211 0.676 1.17 0.916 1.49 0.2 0.122 0.103 0.9886 1.22 0.961 1.55 0.0477 0.126 0.706 0.1514 1.05 0.819 1.34 PRS_PLINK_0.001 FALSE 443.1 Raynaud's syndrome Both 208 2388 8 circulatory system red 2388, 208 597, 47 597, 53 597, 56 597, 52 0.0317 0.0528 0.548 0.2609 1.03 0.931 1.14 0.121 0.207 0.558 0.2535 1.13 0.753 1.69 0.168 0.204 0.409 0.3884 1.18 0.793 1.77 0.0873 0.207 0.673 0.1717 1.09 0.727 1.64 PRS_PLINK_0.001 FALSE 443.7 Peripheral angiopathy in diseases classified elsewhere Both 43 826 8 circulatory system red 826, 43 207, 8 206, 13 206, 13 207, 9 0.117 0.0627 0.0615 1.211 1.12 0.994 1.27 0.47 0.43 0.274 0.5627 1.6 0.689 3.72 0.535 0.43 0.213 0.671 1.71 0.735 3.97 0.209 0.456 0.647 0.1889 1.23 0.504 3.01 PRS_PLINK_0.001 TRUE 443.8 Other specified peripheral vascular diseases Both 548 7473 8 circulatory system red 7473, 548 1869, 123 1868, 145 1868, 151 1868, 129 0.0326 0.0372 0.381 0.4192 1.03 0.96 1.11 0.158 0.126 0.212 0.6744 1.17 0.914 1.5 0.21 0.125 0.0942 1.026 1.23 0.965 1.58 0.0433 0.129 0.738 0.1321 1.04 0.81 1.35 PRS_PLINK_0.001 FALSE 443.9 Peripheral vascular disease, unspecified Both 346 5180 8 circulatory system red 5180, 346 1295, 81 1295, 96 1295, 91 1295, 78 0.0419 0.047 0.373 0.428 1.04 0.951 1.14 0.161 0.155 0.298 0.5256 1.17 0.867 1.59 0.128 0.157 0.413 0.384 1.14 0.836 1.54 -0.0429 0.162 0.791 0.1018 0.958 0.697 1.32 PRS_PLINK_0.001 FALSE 444 Arterial embolism and thrombosis Both 131 1908 8 circulatory system red 1908, 131 477, 29 477, 33 477, 36 477, 33 0.0348 0.0878 0.691 0.1602 1.04 0.872 1.23 0.11 0.258 0.669 0.1746 1.12 0.673 1.85 0.224 0.253 0.376 0.4244 1.25 0.762 2.06 0.143 0.257 0.578 0.2377 1.15 0.697 1.91 PRS_PLINK_0.001 FALSE 444.1 Arterial embolism and thrombosis of lower extremity artery Both 79 1122 8 circulatory system red 1122, 79 281, 14 280, 23 280, 24 281, 18 0.0334 0.0896 0.71 0.1489 1.03 0.867 1.23 0.445 0.338 0.188 0.7261 1.56 0.805 3.03 0.558 0.335 0.0954 1.02 1.75 0.907 3.37 0.284 0.35 0.417 0.3795 1.33 0.669 2.64 PRS_PLINK_0.001 FALSE 446 Polyarteritis nodosa and allied conditions Both 150 1606 8 circulatory system red 1606, 150 402, 34 401, 42 401, 36 402, 38 -0.0108 0.0863 0.9 0.04572 0.989 0.835 1.17 0.202 0.238 0.396 0.4021 1.22 0.768 1.95 0.0585 0.245 0.811 0.0908 1.06 0.656 1.71 0.098 0.243 0.687 0.1632 1.1 0.685 1.78 PRS_PLINK_0.001 FALSE 446.4 Wegener's granulomatosis Both 38 379 8 circulatory system red 379, 38 95, 7 95, 11 94, 8 95, 12 0.268 0.542 0.621 0.2069 1.31 0.452 3.78 0.412 0.476 0.386 0.413 1.51 0.594 3.84 0.241 0.504 0.633 0.1988 1.27 0.474 3.41 0.547 0.481 0.256 0.5919 1.73 0.673 4.44 PRS_PLINK_0.001 TRUE 446.5 Giant cell arteritis Both 64 714 8 circulatory system red 714, 64 179, 18 178, 17 178, 12 179, 17 -0.276 0.411 0.501 0.3002 0.759 0.339 1.7 -0.0277 0.348 0.936 0.0285 0.973 0.492 1.92 -0.351 0.375 0.349 0.4574 0.704 0.338 1.47 -0.0828 0.348 0.812 0.09055 0.921 0.466 1.82 PRS_PLINK_0.001 FALSE 446.9 Arteritis NOS Both 51 492 8 circulatory system red 492, 51 123, 12 123, 16 123, 13 123, 10 -0.613 0.501 0.221 0.6559 0.542 0.203 1.45 0.198 0.389 0.61 0.2145 1.22 0.569 2.62 0.0422 0.406 0.917 0.03753 1.04 0.471 2.31 -0.337 0.437 0.441 0.3559 0.714 0.303 1.68 PRS_PLINK_0.001 FALSE 447 Other disorders of arteries and arterioles Both 185 2782 8 circulatory system red 2782, 185 696, 42 695, 52 695, 41 696, 50 0.0253 0.091 0.781 0.1073 1.03 0.858 1.23 0.214 0.211 0.31 0.5081 1.24 0.819 1.87 -0.00497 0.222 0.982 0.007824 0.995 0.644 1.54 0.176 0.212 0.406 0.3911 1.19 0.787 1.81 PRS_PLINK_0.001 FALSE 447.1 Stricture of artery Both 115 1797 8 circulatory system red 1797, 115 450, 28 449, 29 449, 26 449, 32 0.0439 0.104 0.672 0.1729 1.04 0.853 1.28 0.0439 0.267 0.869 0.06081 1.04 0.619 1.76 -0.0307 0.273 0.911 0.0407 0.97 0.568 1.66 0.134 0.26 0.606 0.2177 1.14 0.687 1.9 PRS_PLINK_0.001 FALSE 448 Disease of capillaries Both 16 284 8 circulatory system red 284, 16 71, 3 71, 1 71, 7 71, 5 0.208 0.122 0.0876 1.058 1.23 0.97 1.56 -0.408 0.892 0.648 0.1888 0.665 0.116 3.82 0.665 0.655 0.31 0.5093 1.95 0.539 7.02 1.01 0.734 0.169 0.7725 2.75 0.651 11.6 PRS_PLINK_0.001 TRUE 450 Noninfectious disorders of lymphatic channels Both 114 1475 8 circulatory system red 1475, 114 369, 27 369, 26 368, 36 369, 25 0.000591 0.082 0.994 0.002504 1 0.852 1.18 -0.0176 0.278 0.95 0.02242 0.983 0.57 1.69 0.263 0.263 0.316 0.4997 1.3 0.777 2.18 -0.105 0.28 0.708 0.1502 0.9 0.52 1.56 PRS_PLINK_0.001 FALSE 451 Phlebitis and thrombophlebitis Both 698 8188 8 circulatory system red 8188, 698 2047, 172 2047, 174 2047, 170 2047, 182 0.0387 0.026 0.136 0.8653 1.04 0.988 1.09 0.00212 0.112 0.985 0.006635 1 0.805 1.25 -0.0109 0.112 0.923 0.03497 0.989 0.794 1.23 0.0565 0.111 0.609 0.2154 1.06 0.852 1.31 PRS_PLINK_0.001 FALSE 451.2 Phlebitis and thrombophlebitis of lower extremities Both 656 7628 8 circulatory system red 7628, 656 1907, 163 1907, 168 1907, 155 1907, 170 0.0337 0.0292 0.249 0.6035 1.03 0.977 1.1 0.0193 0.114 0.866 0.06237 1.02 0.815 1.28 -0.0487 0.116 0.675 0.1705 0.952 0.759 1.2 0.0436 0.114 0.702 0.1539 1.04 0.836 1.31 PRS_PLINK_0.001 FALSE 452 Other venous embolism and thrombosis Both 110 1186 8 circulatory system red 1186, 110 297, 28 296, 23 296, 33 297, 26 0.0637 0.0548 0.245 0.6109 1.07 0.957 1.19 -0.154 0.286 0.59 0.2292 0.857 0.489 1.5 0.19 0.266 0.474 0.3246 1.21 0.719 2.04 -0.065 0.279 0.816 0.08844 0.937 0.542 1.62 PRS_PLINK_0.001 FALSE 454 Varicose veins Both 2140 24107 8 circulatory system red 24107, 2140 6027, 525 6027, 546 6026, 546 6027, 523 0.0146 0.0196 0.457 0.34 1.01 0.976 1.05 0.0388 0.0637 0.542 0.2658 1.04 0.918 1.18 0.0372 0.0637 0.559 0.2525 1.04 0.916 1.18 -0.00473 0.0643 0.941 0.02625 0.995 0.877 1.13 PRS_PLINK_0.001 FALSE 454.1 Varicose veins of lower extremity Both 2168 24626 8 circulatory system red 24626, 2168 6157, 540 6156, 550 6156, 544 6157, 534 0.0123 0.0197 0.531 0.2746 1.01 0.974 1.05 0.0193 0.0631 0.76 0.1191 1.02 0.901 1.15 0.0048 0.0633 0.94 0.02707 1 0.888 1.14 -0.012 0.0636 0.85 0.07072 0.988 0.872 1.12 PRS_PLINK_0.001 FALSE 454.11 Varicose veins of lower extremity, symptomtic Both 128 1337 8 circulatory system red 1337, 128 335, 32 334, 43 334, 27 334, 26 0.0662 0.0638 0.299 0.5241 1.07 0.943 1.21 0.29 0.242 0.231 0.6373 1.34 0.832 2.15 -0.146 0.267 0.583 0.2342 0.864 0.512 1.46 -0.222 0.27 0.41 0.387 0.801 0.472 1.36 PRS_PLINK_0.001 FALSE 455 Hemorrhoids Both 4442 50416 8 circulatory system red 50416, 4442 12604, 1123 12604, 1091 12604, 1097 12604, 1131 0.0254 0.0123 0.0389 1.41 1.03 1 1.05 -0.0274 0.0443 0.537 0.2702 0.973 0.892 1.06 -0.0226 0.0443 0.61 0.2146 0.978 0.896 1.07 0.00916 0.044 0.835 0.07833 1.01 0.926 1.1 PRS_PLINK_0.001 FALSE 456 Chronic venous insufficiency [CVI] Both 38 371 8 circulatory system red 371, 38 93, 12 93, 13 92, 7 93, 6 -1.15 0.569 0.0429 1.368 0.316 0.104 0.964 0.0102 0.414 0.98 0.008627 1.01 0.449 2.27 -0.447 0.47 0.341 0.4672 0.639 0.255 1.61 -0.661 0.483 0.171 0.767 0.516 0.2 1.33 PRS_PLINK_0.001 TRUE 457 Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin Both 13 182 8 circulatory system red 182, 13 46, 3 45, 3 45, 3 46, 4 0.688 0.85 0.418 0.3787 1.99 0.376 10.5 -0.151 0.832 0.856 0.06762 0.86 0.168 4.39 -0.0011 0.739 0.999 0.0005158 0.999 0.235 4.25 0.121 0.717 0.866 0.06246 1.13 0.277 4.6 PRS_PLINK_0.001 TRUE 458 Hypotension Both 948 12040 8 circulatory system red 12040, 948 3010, 223 3010, 243 3010, 234 3010, 248 -0.0033 0.0386 0.932 0.0307 0.997 0.924 1.07 0.0747 0.096 0.437 0.3596 1.08 0.893 1.3 0.0474 0.0969 0.625 0.2041 1.05 0.867 1.27 0.108 0.0956 0.258 0.5886 1.11 0.924 1.34 PRS_PLINK_0.001 FALSE 458.1 Orthostatic hypotension Both 171 2689 8 circulatory system red 2689, 171 673, 37 672, 42 672, 45 672, 47 0.0225 0.0713 0.752 0.1236 1.02 0.889 1.18 0.11 0.227 0.63 0.2006 1.12 0.714 1.74 0.197 0.225 0.381 0.4193 1.22 0.784 1.89 0.227 0.222 0.307 0.5126 1.25 0.812 1.94 PRS_PLINK_0.001 FALSE 458.2 Iatrogenic hypotension Both 35 502 8 circulatory system red 502, 35 126, 7 125, 8 125, 9 126, 11 0.0937 0.102 0.357 0.4471 1.1 0.9 1.34 -0.0215 0.499 0.966 0.01517 0.979 0.368 2.6 0.223 0.494 0.652 0.1855 1.25 0.474 3.29 0.408 0.47 0.386 0.4137 1.5 0.598 3.78 PRS_PLINK_0.001 TRUE 458.9 Hypotension NOS Both 612 7290 8 circulatory system red 7290, 612 1823, 150 1822, 151 1822, 151 1823, 160 0.0396 0.0449 0.378 0.4227 1.04 0.953 1.14 -0.00267 0.119 0.982 0.007803 0.997 0.789 1.26 0.00481 0.12 0.968 0.01415 1 0.795 1.27 0.0663 0.118 0.574 0.2409 1.07 0.848 1.35 PRS_PLINK_0.001 FALSE 459 Other disorders of circulatory system Both 2652 33767 8 circulatory system red 33767, 2652 8441, 619 8442, 676 8441, 666 8442, 691 0.0109 0.0181 0.546 0.2625 1.01 0.976 1.05 0.086 0.0577 0.136 0.8672 1.09 0.973 1.22 0.0725 0.0579 0.21 0.6771 1.08 0.96 1.2 0.108 0.0574 0.0594 1.227 1.11 0.996 1.25 PRS_PLINK_0.001 FALSE 459.1 Hemorrhage NOS Both 28 269 8 circulatory system red 269, 28 68, 12 67, 5 67, 8 67, 3 -1.62 0.631 0.0101 1.997 0.197 0.0573 0.679 -0.678 0.535 0.205 0.6886 0.508 0.178 1.45 -0.388 0.472 0.411 0.3865 0.678 0.269 1.71 -1.12 0.596 0.0608 1.216 0.327 0.102 1.05 PRS_PLINK_0.001 TRUE 459.9 Circulatory disease NEC Both 2620 33503 8 circulatory system red 33503, 2620 8375, 612 8376, 668 8375, 654 8376, 686 0.0168 0.0172 0.329 0.4831 1.02 0.983 1.05 0.0854 0.058 0.141 0.8518 1.09 0.972 1.22 0.0654 0.0583 0.262 0.5822 1.07 0.952 1.2 0.112 0.0577 0.0516 1.288 1.12 0.999 1.25 PRS_PLINK_0.001 FALSE 464 Acute sinusitis Both 36 449 9 respiratory coral4 449, 36 113, 9 112, 9 112, 9 112, 9 -0.501 0.569 0.379 0.4217 0.606 0.198 1.85 -0.104 0.467 0.825 0.0838 0.902 0.361 2.25 -0.0368 0.47 0.937 0.02805 0.964 0.384 2.42 -0.281 0.487 0.564 0.2484 0.755 0.291 1.96 PRS_PLINK_0.001 TRUE 465 Acute upper respiratory infections of multiple or unspecified sites Both 418 4975 9 respiratory coral4 4975, 418 1244, 89 1244, 129 1243, 98 1244, 102 0.0421 0.0351 0.231 0.6366 1.04 0.974 1.12 0.377 0.143 0.00828 2.082 1.46 1.1 1.93 0.0916 0.151 0.544 0.2645 1.1 0.815 1.47 0.12 0.15 0.422 0.3744 1.13 0.841 1.51 PRS_PLINK_0.001 FALSE 465.2 Acute pharyngitis Both 167 1842 9 respiratory coral4 1842, 167 461, 30 460, 56 460, 45 461, 36 0.0356 0.0947 0.706 0.1509 1.04 0.861 1.25 0.63 0.233 0.0069 2.161 1.88 1.19 2.97 0.418 0.241 0.0831 1.08 1.52 0.947 2.44 0.188 0.251 0.452 0.345 1.21 0.739 1.97 PRS_PLINK_0.001 FALSE 465.4 Acute laryngitis and tracheitis Both 31 362 9 respiratory coral4 362, 31 91, 8 90, 9 90, 7 91, 7 -0.496 0.6 0.408 0.3895 0.609 0.188 1.97 0.179 0.482 0.711 0.1482 1.2 0.465 3.08 -0.0852 0.505 0.866 0.06247 0.918 0.341 2.47 -0.262 0.508 0.606 0.2175 0.77 0.285 2.08 PRS_PLINK_0.001 TRUE 470 Septal Deviations/Turbinate Hypertrophy Both 935 10224 9 respiratory coral4 10224, 935 2556, 239 2556, 201 2556, 258 2556, 237 0.0282 0.0295 0.337 0.4718 1.03 0.971 1.09 -0.176 0.0994 0.0775 1.111 0.839 0.69 1.02 0.0757 0.0938 0.42 0.3771 1.08 0.898 1.3 -0.00832 0.0956 0.931 0.03121 0.992 0.822 1.2 PRS_PLINK_0.001 FALSE 471 Nasal polyps Both 685 6878 9 respiratory coral4 6878, 685 1720, 163 1719, 171 1719, 179 1720, 172 0.0448 0.0248 0.0715 1.146 1.05 0.996 1.1 0.046 0.114 0.688 0.1627 1.05 0.837 1.31 0.0973 0.113 0.389 0.4095 1.1 0.883 1.38 0.0473 0.114 0.679 0.1683 1.05 0.838 1.31 PRS_PLINK_0.001 FALSE 472 Chronic pharyngitis and nasopharyngitis Both 179 2018 9 respiratory coral4 2018, 179 505, 56 504, 34 504, 54 505, 35 0.11 0.0521 0.0354 1.451 1.12 1.01 1.24 -0.481 0.225 0.0322 1.492 0.618 0.398 0.96 -0.0353 0.199 0.86 0.06563 0.965 0.653 1.43 -0.429 0.222 0.0533 1.273 0.651 0.422 1.01 PRS_PLINK_0.001 FALSE 473 Diseases of the larynx and vocal cords Both 435 5243 9 respiratory coral4 5243, 435 1311, 95 1311, 113 1310, 112 1311, 115 0.0448 0.0354 0.206 0.6862 1.05 0.976 1.12 0.169 0.144 0.238 0.6234 1.18 0.894 1.57 0.16 0.144 0.266 0.5746 1.17 0.885 1.56 0.187 0.143 0.191 0.7185 1.21 0.911 1.6 PRS_PLINK_0.001 FALSE 473.1 Chronic laryngitis Both 17 227 9 respiratory coral4 227, 17 57, 7 57, 2 56, 4 57, 4 -0.491 0.799 0.539 0.2687 0.612 0.128 2.93 -0.931 0.696 0.181 0.7433 0.394 0.101 1.54 -0.404 0.609 0.507 0.2947 0.668 0.202 2.2 -0.403 0.592 0.496 0.3044 0.669 0.21 2.13 PRS_PLINK_0.001 TRUE 473.3 Paralysis/spasm of vocal cords or larynx Both 40 557 9 respiratory coral4 557, 40 140, 11 139, 8 139, 13 139, 8 0.0723 0.12 0.547 0.2619 1.07 0.85 1.36 -0.444 0.474 0.349 0.4566 0.642 0.253 1.63 0.192 0.411 0.64 0.194 1.21 0.542 2.71 -0.179 0.456 0.694 0.1588 0.836 0.342 2.04 PRS_PLINK_0.001 TRUE 473.4 Voice disturbance Both 186 2159 9 respiratory coral4 2159, 186 540, 40 540, 46 539, 48 540, 52 0.0505 0.0471 0.283 0.5476 1.05 0.959 1.15 0.136 0.221 0.539 0.2686 1.15 0.742 1.77 0.19 0.22 0.386 0.4129 1.21 0.786 1.86 0.252 0.216 0.243 0.6138 1.29 0.843 1.96 PRS_PLINK_0.001 FALSE 474 Acute and chronic tonsillitis Both 357 4058 9 respiratory coral4 4058, 357 1015, 73 1014, 89 1014, 94 1015, 101 0.0496 0.0412 0.228 0.6422 1.05 0.969 1.14 0.181 0.163 0.267 0.5732 1.2 0.871 1.65 0.249 0.161 0.122 0.9146 1.28 0.936 1.76 0.328 0.159 0.0385 1.414 1.39 1.02 1.9 PRS_PLINK_0.001 FALSE 474.1 Acute tonsillitis Both 113 1299 9 respiratory coral4 1299, 113 325, 23 325, 29 324, 29 325, 32 0.0843 0.103 0.411 0.3858 1.09 0.89 1.33 0.195 0.284 0.492 0.3084 1.22 0.697 2.12 0.214 0.282 0.448 0.349 1.24 0.713 2.15 0.324 0.282 0.251 0.6006 1.38 0.795 2.4 PRS_PLINK_0.001 FALSE 474.2 Chronic tonsillitis and adenoiditis Both 215 2508 9 respiratory coral4 2508, 215 627, 42 627, 54 627, 65 627, 54 0.0565 0.0456 0.216 0.6659 1.06 0.968 1.16 0.251 0.212 0.236 0.6272 1.28 0.849 1.95 0.428 0.203 0.0355 1.45 1.53 1.03 2.29 0.27 0.211 0.2 0.6981 1.31 0.866 1.98 PRS_PLINK_0.001 FALSE 475 Chronic sinusitis Both 507 5630 9 respiratory coral4 5630, 507 1407, 123 1407, 136 1407, 120 1408, 128 0.0227 0.035 0.517 0.2864 1.02 0.955 1.1 0.0974 0.129 0.451 0.3454 1.1 0.855 1.42 -0.00885 0.133 0.947 0.02364 0.991 0.763 1.29 0.0337 0.131 0.797 0.09832 1.03 0.799 1.34 PRS_PLINK_0.001 FALSE 476 Allergic rhinitis Both 243 2325 9 respiratory coral4 2325, 243 582, 53 581, 58 581, 71 581, 61 0.00772 0.0419 0.854 0.06869 1.01 0.928 1.09 0.0805 0.197 0.683 0.1655 1.08 0.736 1.59 0.28 0.19 0.141 0.8522 1.32 0.912 1.92 0.125 0.195 0.522 0.2823 1.13 0.773 1.66 PRS_PLINK_0.001 FALSE 477 Epistaxis or throat hemorrhage Both 471 5004 9 respiratory coral4 5004, 471 1251, 123 1251, 128 1251, 113 1251, 107 0.0489 0.0406 0.229 0.6394 1.05 0.97 1.14 0.0518 0.132 0.694 0.1584 1.05 0.813 1.36 -0.0824 0.136 0.544 0.2648 0.921 0.706 1.2 -0.137 0.137 0.321 0.4938 0.872 0.666 1.14 PRS_PLINK_0.001 FALSE 478 Throat pain Both 60 791 9 respiratory coral4 791, 60 198, 17 198, 16 197, 18 198, 9 -0.466 0.457 0.307 0.5122 0.627 0.256 1.54 -0.0698 0.355 0.844 0.07374 0.933 0.465 1.87 0.0738 0.342 0.829 0.08132 1.08 0.551 2.11 -0.561 0.399 0.159 0.7975 0.57 0.261 1.25 PRS_PLINK_0.001 FALSE 479 Other upper respiratory disease Both 749 8642 9 respiratory coral4 8642, 749 2161, 188 2160, 188 2160, 183 2161, 190 0.06 0.0253 0.0175 1.756 1.06 1.01 1.12 -0.000909 0.107 0.993 0.002948 0.999 0.81 1.23 -0.0239 0.108 0.825 0.08362 0.976 0.79 1.21 0.0103 0.107 0.923 0.03457 1.01 0.819 1.25 PRS_PLINK_0.001 FALSE 480 Pneumonia Both 1575 21462 9 respiratory coral4 21462, 1575 5366, 384 5365, 392 5365, 385 5366, 414 -0.062 0.0407 0.128 0.8935 0.94 0.868 1.02 0.0219 0.0742 0.768 0.1145 1.02 0.884 1.18 0.00578 0.0746 0.938 0.02769 1.01 0.869 1.16 0.0773 0.0733 0.292 0.5348 1.08 0.936 1.25 PRS_PLINK_0.001 FALSE 480.1 Bacterial pneumonia Both 1040 13783 9 respiratory coral4 13783, 1040 3446, 247 3446, 254 3445, 253 3446, 286 -0.0427 0.0429 0.32 0.4954 0.958 0.881 1.04 0.0312 0.0923 0.736 0.1334 1.03 0.861 1.24 0.0282 0.0924 0.76 0.119 1.03 0.858 1.23 0.151 0.09 0.0932 1.03 1.16 0.975 1.39 PRS_PLINK_0.001 FALSE 480.11 Pneumococcal pneumonia Both 924 12217 9 respiratory coral4 12217, 924 3055, 216 3054, 223 3054, 232 3054, 253 -0.042 0.0435 0.334 0.4763 0.959 0.881 1.04 0.0357 0.0986 0.717 0.1445 1.04 0.854 1.26 0.0752 0.0977 0.441 0.3554 1.08 0.89 1.31 0.164 0.096 0.0884 1.054 1.18 0.976 1.42 PRS_PLINK_0.001 FALSE 480.12 Pseudomonal pneumonia Both 14 204 9 respiratory coral4 204, 14 51, 2 51, 3 51, 6 51, 3 0.639 0.83 0.441 0.3557 1.9 0.373 9.64 0.263 0.783 0.737 0.1327 1.3 0.28 6.04 1.02 0.742 0.171 0.7666 2.76 0.645 11.8 0.122 0.807 0.88 0.05556 1.13 0.232 5.49 PRS_PLINK_0.001 TRUE 480.2 Viral pneumonia Both 11 134 9 respiratory coral4 134, 11 34, 1 33, 4 33, 0 34, 6 1.21 0.881 0.168 0.7739 3.37 0.599 18.9 1.13 0.872 0.196 0.7078 3.09 0.559 17 -0.0181 1.12 0.987 0.005598 0.982 0.108 8.9 1.38 0.833 0.097 1.013 3.98 0.779 20.4 PRS_PLINK_0.001 TRUE 480.3 Pneumonia due to fungus (mycoses) Both 16 219 9 respiratory coral4 219, 16 55, 1 55, 5 54, 1 55, 9 0.985 0.844 0.244 0.6135 2.68 0.512 14 1.06 0.794 0.183 0.7368 2.87 0.607 13.6 -0.252 0.899 0.779 0.1084 0.777 0.134 4.52 1.64 0.825 0.0465 1.333 5.17 1.03 26 PRS_PLINK_0.001 TRUE 480.5 Bronchopneumonia and lung abscess Both 96 1693 9 respiratory coral4 1693, 96 424, 26 423, 27 423, 15 423, 28 0.0896 0.12 0.457 0.3403 1.09 0.864 1.38 -0.00596 0.278 0.983 0.007505 0.994 0.577 1.71 -0.479 0.32 0.134 0.8745 0.619 0.331 1.16 0.0879 0.274 0.749 0.1258 1.09 0.638 1.87 PRS_PLINK_0.001 FALSE 481 Influenza Both 51 703 9 respiratory coral4 703, 51 176, 11 176, 7 175, 16 176, 17 0.0677 0.115 0.556 0.2552 1.07 0.854 1.34 -0.451 0.457 0.324 0.4901 0.637 0.26 1.56 0.33 0.388 0.395 0.4034 1.39 0.65 2.98 0.344 0.385 0.373 0.4288 1.41 0.663 3 PRS_PLINK_0.001 FALSE 483 Acute bronchitis and bronchiolitis Both 33 432 9 respiratory coral4 432, 33 108, 9 108, 8 108, 5 108, 11 0.0847 0.117 0.471 0.3273 1.09 0.865 1.37 -0.164 0.471 0.728 0.138 0.849 0.337 2.14 -0.368 0.535 0.491 0.3088 0.692 0.243 1.97 0.161 0.445 0.718 0.1438 1.17 0.491 2.81 PRS_PLINK_0.001 TRUE 495 Asthma Both 4840 54374 9 respiratory coral4 54374, 4840 13593, 1157 13593, 1215 13593, 1235 13594, 1233 0.00267 0.0143 0.852 0.06972 1 0.975 1.03 0.0466 0.0428 0.276 0.5585 1.05 0.963 1.14 0.0629 0.0427 0.141 0.8519 1.06 0.979 1.16 0.0633 0.0427 0.138 0.8592 1.07 0.98 1.16 PRS_PLINK_0.001 FALSE 495.2 Asthma with exacerbation Both 37 515 9 respiratory coral4 515, 37 129, 6 129, 8 128, 12 129, 11 0.127 0.0622 0.0415 1.382 1.14 1 1.28 0.229 0.504 0.65 0.187 1.26 0.468 3.38 0.683 0.483 0.157 0.8037 1.98 0.769 5.1 0.586 0.506 0.247 0.6068 1.8 0.666 4.84 PRS_PLINK_0.001 TRUE 496 Chronic airway obstruction Both 1367 20909 9 respiratory coral4 20909, 1367 5228, 299 5227, 358 5227, 339 5227, 371 0.031 0.0208 0.137 0.862 1.03 0.99 1.07 0.178 0.0806 0.0268 1.571 1.2 1.02 1.4 0.125 0.0815 0.125 0.9019 1.13 0.966 1.33 0.214 0.08 0.00749 2.125 1.24 1.06 1.45 PRS_PLINK_0.001 FALSE 496.1 Emphysema Both 210 3523 9 respiratory coral4 3523, 210 881, 43 881, 54 880, 64 881, 49 0.0244 0.0789 0.757 0.1207 1.02 0.878 1.2 0.228 0.206 0.269 0.5694 1.26 0.838 1.88 0.387 0.2 0.0528 1.278 1.47 0.995 2.18 0.101 0.212 0.634 0.1977 1.11 0.731 1.67 PRS_PLINK_0.001 FALSE 496.2 Chronic bronchitis Both 313 5944 9 respiratory coral4 5944, 313 1486, 63 1486, 86 1486, 66 1486, 98 0.052 0.0339 0.125 0.9015 1.05 0.986 1.13 0.316 0.168 0.0598 1.224 1.37 0.987 1.91 0.0438 0.178 0.806 0.09391 1.04 0.737 1.48 0.438 0.164 0.00751 2.124 1.55 1.12 2.14 PRS_PLINK_0.001 FALSE 496.21 Obstructive chronic bronchitis Both 280 5437 9 respiratory coral4 5437, 280 1360, 54 1359, 75 1359, 64 1359, 87 0.0696 0.0349 0.0463 1.335 1.07 1 1.15 0.326 0.18 0.0704 1.153 1.39 0.973 1.97 0.165 0.186 0.376 0.4252 1.18 0.819 1.7 0.472 0.175 0.007 2.155 1.6 1.14 2.26 PRS_PLINK_0.001 FALSE 496.3 Bronchiectasis Both 350 3868 9 respiratory coral4 3868, 350 967, 77 967, 90 967, 89 967, 94 -0.0156 0.0581 0.789 0.1029 0.985 0.879 1.1 0.179 0.161 0.265 0.5767 1.2 0.873 1.64 0.14 0.161 0.383 0.4169 1.15 0.839 1.58 0.209 0.159 0.19 0.7212 1.23 0.902 1.68 PRS_PLINK_0.001 FALSE 497 Bronchitis Both 90 1294 9 respiratory coral4 1294, 90 324, 16 323, 25 323, 23 324, 26 0.117 0.063 0.064 1.194 1.12 0.993 1.27 0.491 0.321 0.126 0.9003 1.63 0.871 3.06 0.362 0.324 0.263 0.5795 1.44 0.762 2.71 0.469 0.316 0.138 0.859 1.6 0.86 2.97 PRS_PLINK_0.001 FALSE 500 Lung disease due to external agents Both 50 819 9 respiratory coral4 819, 50 205, 12 205, 16 204, 13 205, 9 0.0253 0.0718 0.724 0.1402 1.03 0.891 1.18 0.383 0.388 0.323 0.4907 1.47 0.686 3.14 0.176 0.402 0.663 0.1788 1.19 0.542 2.62 -0.084 0.449 0.852 0.06973 0.919 0.381 2.22 PRS_PLINK_0.001 TRUE 500.1 Extrinsic allergic alveolitis Both 9 157 9 respiratory coral4 157, 9 40, 3 39, 1 39, 3 39, 2 -1.09 0.987 0.269 0.571 0.336 0.0486 2.32 0.323 0.846 0.703 0.1532 1.38 0.263 7.25 -0.151 0.943 0.873 0.05908 0.86 0.135 5.46 PRS_PLINK_0.001 TRUE 500.2 Pneumoconiosis Both 29 473 9 respiratory coral4 473, 29 119, 6 118, 11 118, 7 118, 5 0.0558 0.0688 0.418 0.3791 1.06 0.924 1.21 0.956 0.53 0.0713 1.147 2.6 0.921 7.35 0.503 0.57 0.378 0.4228 1.65 0.541 5.05 0.265 0.616 0.668 0.1754 1.3 0.389 4.36 PRS_PLINK_0.001 TRUE 501 Pneumonitis due to inhalation of food or vomitus Both 85 1367 9 respiratory coral4 1367, 85 342, 30 342, 17 341, 21 342, 17 -0.815 0.365 0.0256 1.591 0.443 0.216 0.906 -0.602 0.305 0.0482 1.317 0.548 0.301 0.995 -0.383 0.288 0.184 0.7361 0.682 0.388 1.2 -0.577 0.307 0.0602 1.221 0.561 0.307 1.02 PRS_PLINK_0.001 FALSE 502 Postinflammatory pulmonary fibrosis Both 118 1858 9 respiratory coral4 1858, 118 465, 20 464, 31 464, 34 465, 33 0.0389 0.0722 0.59 0.2293 1.04 0.902 1.2 0.468 0.285 0.1 0.9981 1.6 0.914 2.79 0.477 0.281 0.0897 1.047 1.61 0.929 2.8 0.441 0.282 0.118 0.9266 1.55 0.894 2.7 PRS_PLINK_0.001 FALSE 503 Pulmonary congestion and hypostasis Both 71 991 9 respiratory coral4 991, 71 248, 20 248, 19 247, 19 248, 13 0.0765 0.129 0.553 0.2574 1.08 0.838 1.39 -0.0712 0.325 0.826 0.08285 0.931 0.493 1.76 -0.0397 0.324 0.902 0.04462 0.961 0.51 1.81 -0.399 0.352 0.256 0.591 0.671 0.337 1.34 PRS_PLINK_0.001 FALSE 504 Other alveolar and parietoalveolar pneumonopathy Both 48 656 9 respiratory coral4 656, 48 164, 11 164, 10 164, 16 164, 11 0.0502 0.119 0.673 0.172 1.05 0.833 1.33 -0.13 0.427 0.761 0.1185 0.878 0.381 2.03 0.317 0.397 0.424 0.3726 1.37 0.631 2.99 0.0169 0.418 0.968 0.01426 1.02 0.448 2.31 PRS_PLINK_0.001 TRUE 505 Other pulmonary inflamation or edema Both 9 138 9 respiratory coral4 138, 9 35, 2 34, 2 34, 4 35, 1 -0.0672 0.999 0.946 0.02394 0.935 0.132 6.63 -0.349 0.893 0.696 0.1574 0.705 0.122 4.06 0.754 0.882 0.392 0.4062 2.13 0.378 12 -0.291 0.925 0.753 0.1234 0.747 0.122 4.58 PRS_PLINK_0.001 TRUE 506 Empyema and pneumothorax Both 174 2408 9 respiratory coral4 2408, 174 602, 25 602, 43 602, 50 602, 56 0.0664 0.0423 0.117 0.9327 1.07 0.984 1.16 0.528 0.252 0.0362 1.441 1.69 1.03 2.78 0.717 0.247 0.00372 2.429 2.05 1.26 3.33 0.792 0.243 0.00112 2.952 2.21 1.37 3.56 PRS_PLINK_0.001 FALSE 507 Pleurisy; pleural effusion Both 976 13213 9 respiratory coral4 13213, 976 3304, 249 3303, 222 3303, 262 3303, 243 -0.0637 0.0518 0.219 0.6589 0.938 0.848 1.04 -0.115 0.0953 0.228 0.6429 0.891 0.74 1.07 0.052 0.0916 0.571 0.2435 1.05 0.88 1.26 -0.024 0.0932 0.797 0.09877 0.976 0.813 1.17 PRS_PLINK_0.001 FALSE 508 Pulmonary collapse; interstitial and compensatory emphysema Both 316 4266 9 respiratory coral4 4266, 316 1067, 77 1066, 70 1066, 78 1067, 91 0.0502 0.0448 0.263 0.5803 1.05 0.963 1.15 -0.0789 0.17 0.642 0.1924 0.924 0.662 1.29 0.0039 0.165 0.981 0.008255 1 0.726 1.39 0.174 0.16 0.277 0.5579 1.19 0.87 1.63 PRS_PLINK_0.001 FALSE 509 Respiratory failure, insufficiency, arrest Both 329 5472 9 respiratory coral4 5472, 329 1368, 81 1368, 78 1368, 106 1368, 64 -0.0496 0.109 0.648 0.1887 0.952 0.769 1.18 -0.0394 0.162 0.808 0.09282 0.961 0.7 1.32 0.265 0.151 0.0794 1.1 1.3 0.969 1.75 -0.228 0.17 0.179 0.748 0.796 0.571 1.11 PRS_PLINK_0.001 FALSE 509.1 Respiratory failure Both 270 4328 9 respiratory coral4 4328, 270 1082, 68 1082, 67 1082, 83 1082, 52 -0.311 0.209 0.136 0.8649 0.733 0.486 1.1 -0.00786 0.176 0.964 0.0158 0.992 0.703 1.4 0.196 0.168 0.242 0.6158 1.22 0.876 1.69 -0.262 0.186 0.16 0.7947 0.77 0.534 1.11 PRS_PLINK_0.001 FALSE 509.2 Respiratory insufficiency Both 224 3802 9 respiratory coral4 3802, 224 951, 59 950, 53 950, 67 951, 45 -0.321 0.226 0.155 0.8084 0.725 0.466 1.13 -0.101 0.192 0.6 0.2218 0.904 0.621 1.32 0.131 0.182 0.472 0.3264 1.14 0.798 1.63 -0.267 0.2 0.182 0.74 0.766 0.518 1.13 PRS_PLINK_0.001 FALSE 509.5 Respiratory arrest Both 15 289 9 respiratory coral4 289, 15 73, 3 72, 3 72, 5 72, 4 1.05 0.853 0.217 0.6637 2.87 0.539 15.3 0.174 0.759 0.819 0.08674 1.19 0.269 5.26 0.461 0.692 0.505 0.2966 1.59 0.409 6.15 0.893 0.746 0.232 0.6353 2.44 0.566 10.5 PRS_PLINK_0.001 TRUE 509.8 Dependence on respirator [Ventilator] or supplemental oxygen Both 43 781 9 respiratory coral4 781, 43 196, 9 195, 9 195, 12 195, 13 0.0678 0.0929 0.466 0.332 1.07 0.892 1.28 -0.058 0.447 0.897 0.04734 0.944 0.393 2.26 0.344 0.425 0.418 0.3785 1.41 0.613 3.24 0.374 0.417 0.369 0.4326 1.45 0.642 3.29 PRS_PLINK_0.001 TRUE 510 Other diseases of lung Both 121 1615 9 respiratory coral4 1615, 121 404, 44 404, 32 403, 22 404, 23 -0.673 0.329 0.041 1.388 0.51 0.268 0.973 -0.297 0.239 0.215 0.6673 0.743 0.465 1.19 -0.689 0.264 0.00916 2.038 0.502 0.299 0.843 -0.629 0.26 0.0158 1.802 0.533 0.32 0.889 PRS_PLINK_0.001 FALSE 512 Other symptoms of respiratory system Both 1495 18773 9 respiratory coral4 18773, 1495 4694, 374 4693, 378 4693, 366 4693, 377 -0.0159 0.0314 0.612 0.2131 0.984 0.926 1.05 0.0111 0.0757 0.883 0.05385 1.01 0.872 1.17 -0.0204 0.0763 0.789 0.1028 0.98 0.844 1.14 0.00808 0.0757 0.915 0.0386 1.01 0.869 1.17 PRS_PLINK_0.001 FALSE 512.1 Wheezing Both 38 445 9 respiratory coral4 445, 38 112, 9 111, 13 111, 8 111, 8 0.0611 0.124 0.623 0.2057 1.06 0.833 1.36 0.428 0.445 0.336 0.4738 1.53 0.641 3.67 -0.0964 0.472 0.838 0.07658 0.908 0.36 2.29 -0.0484 0.481 0.92 0.03627 0.953 0.371 2.45 PRS_PLINK_0.001 TRUE 512.2 Painful respiration Both 39 436 9 respiratory coral4 436, 39 109, 10 109, 11 109, 10 109, 8 -0.475 0.528 0.369 0.433 0.622 0.221 1.75 0.0131 0.438 0.976 0.01049 1.01 0.43 2.39 -0.116 0.452 0.797 0.09828 0.891 0.367 2.16 -0.222 0.466 0.634 0.198 0.801 0.322 2 PRS_PLINK_0.001 TRUE 512.7 Shortness of breath Both 922 12072 9 respiratory coral4 12072, 922 3018, 234 3018, 231 3018, 227 3018, 230 -0.0108 0.0409 0.793 0.101 0.989 0.913 1.07 -0.0113 0.096 0.906 0.04287 0.989 0.819 1.19 -0.0269 0.0965 0.78 0.1077 0.973 0.806 1.18 -0.0187 0.096 0.846 0.0728 0.981 0.813 1.18 PRS_PLINK_0.001 FALSE 512.8 Cough Both 498 5982 9 respiratory coral4 5982, 498 1496, 114 1495, 123 1495, 111 1496, 150 0.0373 0.0402 0.353 0.4521 1.04 0.959 1.12 0.0816 0.134 0.543 0.2649 1.09 0.834 1.41 -0.0246 0.138 0.858 0.06637 0.976 0.745 1.28 0.273 0.129 0.0342 1.466 1.31 1.02 1.69 PRS_PLINK_0.001 FALSE 512.9 Other dyspnea Both 152 1871 9 respiratory coral4 1871, 152 468, 30 468, 45 467, 43 468, 34 0.0265 0.0788 0.737 0.1326 1.03 0.88 1.2 0.456 0.242 0.0589 1.23 1.58 0.983 2.53 0.364 0.244 0.136 0.8659 1.44 0.892 2.32 0.111 0.254 0.66 0.1803 1.12 0.68 1.84 PRS_PLINK_0.001 FALSE 513 Respiratory abnormalities Both 89 1247 9 respiratory coral4 1247, 89 312, 21 312, 22 311, 20 312, 26 0.111 0.0625 0.0762 1.118 1.12 0.988 1.26 0.00572 0.307 0.985 0.006507 1.01 0.551 1.83 -0.0746 0.312 0.811 0.09082 0.928 0.503 1.71 0.171 0.296 0.564 0.2484 1.19 0.664 2.12 PRS_PLINK_0.001 FALSE 513.3 Hypoventilation Both 10 167 9 respiratory coral4 167, 10 42, 2 42, 4 41, 1 42, 3 0.623 0.75 0.407 0.3908 1.86 0.428 8.11 -0.536 0.885 0.545 0.2636 0.585 0.103 3.32 -0.0114 0.837 0.989 0.004752 0.989 0.192 5.09 PRS_PLINK_0.001 TRUE 513.4 Hyperventilation Both 35 599 9 respiratory coral4 599, 35 150, 11 150, 7 149, 5 150, 12 -0.49 0.579 0.397 0.4008 0.613 0.197 1.9 -0.377 0.461 0.414 0.3832 0.686 0.278 1.69 -0.692 0.497 0.163 0.7871 0.5 0.189 1.32 0.0859 0.414 0.835 0.0781 1.09 0.484 2.45 PRS_PLINK_0.001 TRUE 513.8 Disorders of diaphragm Both 29 344 9 respiratory coral4 344, 29 86, 6 86, 7 86, 11 86, 5 0.192 0.118 0.105 0.9778 1.21 0.961 1.53 0.0456 0.559 0.935 0.0292 1.05 0.35 3.13 0.508 0.509 0.319 0.4966 1.66 0.613 4.51 0.00669 0.588 0.991 0.003956 1.01 0.318 3.19 PRS_PLINK_0.001 TRUE 514 Abnormal findings examination of lungs Both 354 4999 9 respiratory coral4 4999, 354 1250, 88 1250, 83 1249, 83 1250, 100 0.00945 0.0731 0.897 0.04715 1.01 0.875 1.16 -0.0667 0.157 0.671 0.1735 0.935 0.688 1.27 -0.05 0.157 0.75 0.1248 0.951 0.699 1.29 0.119 0.151 0.429 0.3672 1.13 0.838 1.51 PRS_PLINK_0.001 FALSE 516 Abnormal sputum Both 306 4442 9 respiratory coral4 4442, 306 1111, 70 1110, 83 1110, 75 1111, 78 -0.0315 0.0722 0.662 0.1791 0.969 0.841 1.12 0.173 0.166 0.298 0.5258 1.19 0.858 1.65 0.082 0.17 0.63 0.2006 1.09 0.778 1.52 0.116 0.168 0.492 0.3078 1.12 0.807 1.56 PRS_PLINK_0.001 FALSE 516.1 Hemoptysis Both 293 4301 9 respiratory coral4 4301, 293 1076, 63 1075, 83 1075, 77 1075, 70 -0.0373 0.0734 0.612 0.2136 0.963 0.834 1.11 0.275 0.171 0.107 0.9691 1.32 0.942 1.84 0.21 0.174 0.227 0.6444 1.23 0.878 1.73 0.114 0.177 0.517 0.2861 1.12 0.793 1.59 PRS_PLINK_0.001 FALSE 519 Other diseases of respiratory system, not elsewhere classified Both 1424 19475 9 respiratory coral4 19475, 1424 4869, 343 4869, 371 4868, 333 4869, 377 0.00312 0.0254 0.902 0.0447 1 0.954 1.05 0.0806 0.0775 0.298 0.5253 1.08 0.931 1.26 -0.028 0.0794 0.725 0.1399 0.972 0.832 1.14 0.0975 0.0772 0.207 0.6851 1.1 0.948 1.28 PRS_PLINK_0.001 FALSE 519.2 Respiratory complications Both 39 702 9 respiratory coral4 702, 39 176, 13 175, 11 175, 9 176, 6 -0.547 0.56 0.329 0.4832 0.578 0.193 1.74 -0.0715 0.411 0.862 0.06463 0.931 0.416 2.08 -0.376 0.422 0.374 0.4275 0.687 0.3 1.57 -0.64 0.465 0.169 0.7729 0.527 0.212 1.31 PRS_PLINK_0.001 TRUE 519.8 Other diseases of respiratory system, NEC Both 1325 18326 9 respiratory coral4 18326, 1325 4582, 315 4581, 352 4581, 311 4582, 347 0.00436 0.0252 0.862 0.06428 1 0.956 1.06 0.112 0.0802 0.161 0.7931 1.12 0.956 1.31 -0.00886 0.0825 0.914 0.03885 0.991 0.843 1.17 0.0992 0.0805 0.218 0.662 1.1 0.943 1.29 PRS_PLINK_0.001 FALSE 519.9 Symptoms involving respiratory system and other chest symptoms Both 59 660 9 respiratory coral4 660, 59 165, 17 165, 10 165, 17 165, 15 0.0253 0.104 0.807 0.0931 1.03 0.837 1.26 -0.502 0.396 0.205 0.688 0.605 0.278 1.32 -0.0454 0.35 0.897 0.04731 0.956 0.481 1.9 -0.106 0.357 0.766 0.1156 0.899 0.447 1.81 PRS_PLINK_0.001 FALSE 520 Disorders of tooth development Both 447 4644 10 digestive chartreuse4 4644, 447 1161, 130 1161, 103 1161, 107 1161, 107 -0.328 0.164 0.0461 1.336 0.72 0.522 0.994 -0.231 0.138 0.0928 1.033 0.793 0.606 1.04 -0.193 0.136 0.157 0.8043 0.825 0.632 1.08 -0.193 0.136 0.157 0.805 0.824 0.631 1.08 PRS_PLINK_0.001 FALSE 520.1 Hereditary disturbances in tooth structure Both 16 103 10 digestive chartreuse4 103, 16 26, 5 26, 3 25, 2 26, 6 -0.0194 0.919 0.983 0.007374 0.981 0.162 5.94 -0.654 0.815 0.422 0.3746 0.52 0.105 2.57 -0.963 0.84 0.252 0.599 0.382 0.0736 1.98 0.45 0.709 0.525 0.2794 1.57 0.391 6.3 PRS_PLINK_0.001 TRUE 520.2 Disturbances in tooth eruption Both 495 5289 10 digestive chartreuse4 5289, 495 1323, 139 1322, 116 1322, 125 1322, 115 -0.297 0.154 0.0531 1.275 0.743 0.55 1 -0.174 0.131 0.184 0.7342 0.84 0.65 1.09 -0.107 0.129 0.403 0.3942 0.898 0.698 1.16 -0.186 0.131 0.157 0.8054 0.83 0.642 1.07 PRS_PLINK_0.001 FALSE 521 Diseases of hard tissues of teeth Both 579 6729 10 digestive chartreuse4 6729, 579 1683, 143 1682, 130 1682, 158 1682, 148 0.00501 0.0383 0.896 0.04769 1.01 0.932 1.08 -0.0905 0.125 0.47 0.3275 0.913 0.715 1.17 0.1 0.12 0.402 0.3956 1.11 0.874 1.4 0.0493 0.122 0.686 0.1638 1.05 0.827 1.33 PRS_PLINK_0.001 FALSE 521.1 Dental caries Both 574 6776 10 digestive chartreuse4 6776, 574 1694, 140 1694, 130 1694, 158 1694, 146 -9.86e-05 0.0366 0.998 0.0009338 1 0.931 1.07 -0.0684 0.126 0.587 0.2313 0.934 0.73 1.2 0.121 0.121 0.316 0.5 1.13 0.891 1.43 0.057 0.123 0.643 0.192 1.06 0.832 1.35 PRS_PLINK_0.001 FALSE 522 Diseases of pulp and periapical tissues Both 308 3934 10 digestive chartreuse4 3934, 308 984, 73 983, 73 983, 87 984, 75 0.00885 0.0662 0.894 0.04889 1.01 0.886 1.15 -0.0143 0.17 0.933 0.03006 0.986 0.706 1.38 0.177 0.164 0.278 0.5552 1.19 0.866 1.65 0.0258 0.169 0.879 0.05621 1.03 0.737 1.43 PRS_PLINK_0.001 FALSE 522.5 Periapical abscess Both 184 2630 10 digestive chartreuse4 2630, 184 658, 44 657, 41 657, 55 658, 44 0.0328 0.0803 0.683 0.1658 1.03 0.883 1.21 -0.0851 0.22 0.7 0.1552 0.918 0.596 1.41 0.223 0.207 0.281 0.5519 1.25 0.834 1.87 0.00283 0.217 0.99 0.004547 1 0.656 1.53 PRS_PLINK_0.001 FALSE 523 Gingival and periodontal diseases Both 321 3699 10 digestive chartreuse4 3699, 321 925, 78 925, 88 924, 72 925, 83 0.0153 0.0466 0.742 0.1295 1.02 0.927 1.11 0.133 0.161 0.411 0.3866 1.14 0.833 1.57 -0.0742 0.168 0.659 0.1809 0.928 0.668 1.29 0.0734 0.163 0.653 0.1849 1.08 0.781 1.48 PRS_PLINK_0.001 FALSE 523.1 Gingivitis Both 20 240 10 digestive chartreuse4 240, 20 60, 5 60, 3 60, 7 60, 5 0.0634 0.174 0.716 0.145 1.07 0.757 1.5 -0.448 0.661 0.498 0.303 0.639 0.175 2.33 0.154 0.572 0.788 0.1034 1.17 0.38 3.58 -0.0301 0.604 0.96 0.01764 0.97 0.297 3.17 PRS_PLINK_0.001 TRUE 523.3 Periodontitis (acute or chronic) Both 237 2611 10 digestive chartreuse4 2611, 237 653, 59 653, 75 652, 49 653, 54 0.0138 0.0503 0.784 0.1058 1.01 0.919 1.12 0.252 0.182 0.166 0.7811 1.29 0.901 1.84 -0.169 0.199 0.394 0.4045 0.844 0.572 1.25 -0.0757 0.194 0.696 0.1573 0.927 0.634 1.36 PRS_PLINK_0.001 FALSE 523.31 Acute periodontitis Both 132 1501 10 digestive chartreuse4 1501, 132 376, 22 375, 41 375, 34 375, 35 0.0122 0.0766 0.873 0.05897 1.01 0.871 1.18 0.654 0.27 0.0154 1.813 1.92 1.13 3.26 0.448 0.277 0.105 0.979 1.57 0.911 2.69 0.492 0.276 0.0745 1.128 1.64 0.952 2.81 PRS_PLINK_0.001 FALSE 523.32 Chronic periodontitis Both 114 1170 10 digestive chartreuse4 1170, 114 293, 35 292, 36 292, 20 293, 23 0.0404 0.0556 0.468 0.3298 1.04 0.934 1.16 -0.0132 0.249 0.958 0.01874 0.987 0.606 1.61 -0.589 0.286 0.0396 1.402 0.555 0.317 0.972 -0.384 0.275 0.163 0.788 0.681 0.397 1.17 PRS_PLINK_0.001 FALSE 524 Dentofacial anomalies, including malocclusion Both 75 776 10 digestive chartreuse4 776, 75 194, 18 194, 14 194, 18 194, 25 0.101 0.111 0.359 0.4455 1.11 0.891 1.37 -0.189 0.358 0.598 0.2229 0.828 0.41 1.67 0.0624 0.339 0.854 0.06851 1.06 0.547 2.07 0.335 0.322 0.299 0.525 1.4 0.743 2.63 PRS_PLINK_0.001 FALSE 524.3 Anomalies of tooth position/malocclusion Both 67 716 10 digestive chartreuse4 716, 67 179, 16 179, 12 179, 14 179, 25 0.0649 0.0892 0.466 0.3313 1.07 0.896 1.27 -0.209 0.379 0.582 0.2353 0.811 0.386 1.71 -0.063 0.367 0.864 0.06366 0.939 0.457 1.93 0.454 0.33 0.169 0.7717 1.58 0.824 3.01 PRS_PLINK_0.001 FALSE 525 Other diseases of the teeth and supporting structures Both 533 5656 10 digestive chartreuse4 5656, 533 1414, 129 1414, 127 1414, 134 1414, 143 0.00337 0.0391 0.931 0.03094 1 0.929 1.08 -0.00997 0.13 0.939 0.02742 0.99 0.768 1.28 0.0596 0.129 0.643 0.1916 1.06 0.825 1.37 0.106 0.127 0.403 0.3945 1.11 0.867 1.42 PRS_PLINK_0.001 FALSE 525.2 Atrophy of edentulous alveolar ridge Both 16 156 10 digestive chartreuse4 156, 16 39, 4 39, 3 39, 2 39, 7 0.508 0.807 0.529 0.2763 1.66 0.342 8.08 -0.0978 0.718 0.892 0.0498 0.907 0.222 3.71 -0.468 0.774 0.546 0.263 0.626 0.137 2.86 0.551 0.619 0.373 0.4279 1.74 0.516 5.84 PRS_PLINK_0.001 TRUE 526 Diseases of the jaws Both 184 1996 10 digestive chartreuse4 1996, 184 499, 55 499, 43 499, 44 499, 42 -0.396 0.257 0.122 0.9123 0.673 0.407 1.11 -0.246 0.211 0.242 0.6157 0.782 0.517 1.18 -0.226 0.21 0.281 0.5516 0.797 0.528 1.2 -0.272 0.213 0.2 0.6985 0.762 0.502 1.16 PRS_PLINK_0.001 FALSE 526.1 Cysts of the jaws Both 73 698 10 digestive chartreuse4 698, 73 175, 29 174, 17 174, 17 175, 10 -1.25 0.435 0.0039 2.409 0.285 0.122 0.669 -0.457 0.322 0.156 0.8066 0.633 0.337 1.19 -0.497 0.324 0.125 0.9024 0.608 0.322 1.15 -0.968 0.368 0.00847 2.072 0.38 0.185 0.781 PRS_PLINK_0.001 FALSE 526.3 Anomalies of jaw size/symmetry Both 9 138 10 digestive chartreuse4 138, 9 35, 4 34, 1 34, 2 35, 2 -0.497 1.07 0.642 0.1924 0.608 0.0747 4.95 -1.17 0.863 0.176 0.7543 0.311 0.0574 1.69 -0.375 0.872 0.667 0.1758 0.687 0.124 3.8 -0.963 0.848 0.256 0.5917 0.382 0.0724 2.01 PRS_PLINK_0.001 TRUE 526.4 Temporomandibular joint disorders Both 51 498 10 digestive chartreuse4 498, 51 125, 11 124, 12 124, 14 125, 14 0.0145 0.085 0.865 0.063 1.01 0.859 1.2 0.0815 0.425 0.848 0.07159 1.08 0.471 2.5 0.31 0.413 0.453 0.3436 1.36 0.607 3.06 0.212 0.407 0.602 0.2204 1.24 0.557 2.75 PRS_PLINK_0.001 FALSE 526.41 Temporomandibular joint disorder, unspecified Both 50 481 10 digestive chartreuse4 481, 50 121, 11 120, 12 120, 13 120, 14 0.0152 0.085 0.858 0.06641 1.02 0.859 1.2 0.00829 0.425 0.984 0.006816 1.01 0.438 2.32 0.224 0.417 0.592 0.2277 1.25 0.552 2.83 0.199 0.41 0.627 0.2029 1.22 0.547 2.73 PRS_PLINK_0.001 TRUE 526.5 Inflammatory conditions of jaw Both 24 254 10 digestive chartreuse4 254, 24 64, 4 63, 5 63, 10 64, 5 0.0314 0.0748 0.674 0.1711 1.03 0.891 1.19 0.355 0.702 0.613 0.2125 1.43 0.36 5.65 0.85 0.576 0.14 0.8532 2.34 0.756 7.24 0.392 0.68 0.564 0.2484 1.48 0.39 5.62 PRS_PLINK_0.001 TRUE 526.9 Jaw disease NOS Both 31 469 10 digestive chartreuse4 469, 31 118, 10 117, 5 117, 4 117, 12 0.0708 0.0976 0.469 0.3291 1.07 0.886 1.3 -0.433 0.522 0.406 0.3915 0.648 0.233 1.8 -0.797 0.537 0.137 0.8619 0.451 0.157 1.29 0.307 0.445 0.489 0.3103 1.36 0.569 3.25 PRS_PLINK_0.001 TRUE 527 Diseases of the salivary glands Both 115 1514 10 digestive chartreuse4 1514, 115 379, 17 378, 43 378, 27 379, 28 0.0653 0.0883 0.46 0.3377 1.07 0.898 1.27 0.924 0.289 0.00137 2.864 2.52 1.43 4.44 0.423 0.307 0.169 0.7731 1.53 0.836 2.79 0.461 0.305 0.131 0.8827 1.59 0.872 2.88 PRS_PLINK_0.001 FALSE 527.1 Hypertrophy of salivary gland Both 23 184 10 digestive chartreuse4 184, 23 46, 5 46, 8 46, 4 46, 6 -3.9 0.788 7.28e-07 6.138 0.0202 0.00432 0.0946 0.343 0.598 0.566 0.2469 1.41 0.437 4.55 -0.335 0.696 0.63 0.2007 0.715 0.183 2.8 0.0547 0.654 0.933 0.02997 1.06 0.293 3.8 PRS_PLINK_0.001 TRUE 527.2 Sialoadenitis Both 51 800 10 digestive chartreuse4 800, 51 200, 7 200, 18 200, 12 200, 14 0.6 0.457 0.189 0.7238 1.82 0.745 4.46 0.983 0.433 0.0232 1.634 2.67 1.14 6.24 0.416 0.448 0.353 0.4523 1.52 0.63 3.65 0.7 0.443 0.114 0.9434 2.01 0.845 4.79 PRS_PLINK_0.001 FALSE 527.7 Disturbance of salivary secretion Both 7 150 10 digestive chartreuse4 150, 7 38, 3 37, 2 37, 1 38, 1 -0.411 1.2 0.731 0.1359 0.663 0.0636 6.92 -0.198 0.83 0.812 0.09069 0.82 0.161 4.17 -0.366 0.967 0.705 0.1517 0.694 0.104 4.62 -0.035 0.922 0.97 0.01334 0.966 0.158 5.88 PRS_PLINK_0.001 TRUE 527.8 Other specified diseases of the salivary glands Both 23 242 10 digestive chartreuse4 242, 23 61, 2 60, 9 60, 7 61, 5 0.998 0.628 0.112 0.9508 2.71 0.792 9.3 1.72 0.757 0.0232 1.635 5.58 1.26 24.6 1.16 0.7 0.0981 1.008 3.18 0.807 12.6 0.545 0.705 0.439 0.3571 1.72 0.433 6.86 PRS_PLINK_0.001 TRUE 528 Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue Both 753 8270 10 digestive chartreuse4 8270, 753 2067, 194 2067, 198 2067, 173 2068, 188 0.0179 0.0354 0.613 0.2126 1.02 0.95 1.09 0.0197 0.105 0.852 0.06964 1.02 0.83 1.25 -0.113 0.109 0.297 0.5275 0.893 0.721 1.1 -0.0268 0.107 0.801 0.09615 0.974 0.79 1.2 PRS_PLINK_0.001 FALSE 528.1 Stomatitis and mucositis Both 79 1002 10 digestive chartreuse4 1002, 79 251, 19 250, 25 250, 16 251, 19 0.068 0.0562 0.227 0.6445 1.07 0.959 1.2 0.257 0.307 0.404 0.3941 1.29 0.708 2.36 -0.149 0.336 0.658 0.1819 0.862 0.446 1.67 0.0346 0.325 0.915 0.03844 1.04 0.547 1.96 PRS_PLINK_0.001 FALSE 528.11 Stomatitis and mucositis (ulcerative) Both 61 841 10 digestive chartreuse4 841, 61 211, 13 210, 19 210, 14 210, 15 0.0779 0.0557 0.162 0.7893 1.08 0.969 1.21 0.391 0.36 0.278 0.5565 1.48 0.73 2.99 0.114 0.377 0.763 0.1176 1.12 0.535 2.35 0.124 0.37 0.738 0.1318 1.13 0.548 2.34 PRS_PLINK_0.001 FALSE 528.12 Oral aphthae Both 19 171 10 digestive chartreuse4 171, 19 43, 6 43, 6 42, 3 43, 4 -0.565 0.769 0.462 0.3351 0.568 0.126 2.57 0.187 0.593 0.752 0.1238 1.21 0.377 3.85 -0.458 0.669 0.494 0.3066 0.633 0.171 2.35 -0.241 0.704 0.732 0.1354 0.786 0.198 3.12 PRS_PLINK_0.001 TRUE 528.3 Cellulitis and abscess of oral soft tissues Both 41 407 10 digestive chartreuse4 407, 41 102, 7 102, 10 101, 15 102, 9 0.0496 0.113 0.661 0.1798 1.05 0.842 1.31 0.0499 0.496 0.92 0.03632 1.05 0.398 2.78 0.598 0.459 0.193 0.7153 1.82 0.74 4.47 0.222 0.496 0.655 0.1837 1.25 0.472 3.3 PRS_PLINK_0.001 TRUE 528.4 Cysts of oral soft tissues Both 20 254 10 digestive chartreuse4 254, 20 64, 2 63, 7 63, 6 64, 5 0.463 0.741 0.532 0.274 1.59 0.372 6.78 0.922 0.685 0.178 0.7492 2.51 0.657 9.62 0.847 0.708 0.232 0.6347 2.33 0.582 9.35 0.532 0.758 0.483 0.3165 1.7 0.385 7.53 PRS_PLINK_0.001 TRUE 528.41 Cyst of the salivary gland Both 15 195 10 digestive chartreuse4 195, 15 49, 2 49, 6 48, 4 49, 3 0.232 0.834 0.781 0.1074 1.26 0.246 6.47 0.771 0.722 0.286 0.544 2.16 0.525 8.9 0.36 0.741 0.627 0.2029 1.43 0.335 6.13 0.149 0.854 0.861 0.06475 1.16 0.218 6.19 PRS_PLINK_0.001 TRUE 528.5 Diseases of lips Both 134 1458 10 digestive chartreuse4 1458, 134 365, 32 364, 37 364, 26 365, 39 0.0128 0.0788 0.87 0.06024 1.01 0.868 1.18 0.142 0.249 0.568 0.2458 1.15 0.708 1.88 -0.205 0.269 0.446 0.3508 0.815 0.481 1.38 0.208 0.246 0.399 0.3988 1.23 0.759 1.99 PRS_PLINK_0.001 FALSE 528.6 Leukoplakia of oral mucosa Both 68 649 10 digestive chartreuse4 649, 68 163, 17 162, 21 162, 12 162, 18 0.0299 0.116 0.796 0.09882 1.03 0.821 1.29 0.218 0.338 0.519 0.2845 1.24 0.641 2.41 -0.347 0.384 0.366 0.4371 0.707 0.333 1.5 0.0362 0.348 0.917 0.03756 1.04 0.525 2.05 PRS_PLINK_0.001 FALSE 528.7 Sialolithiasis Both 55 644 10 digestive chartreuse4 644, 55 161, 10 161, 17 161, 17 161, 11 0.23 0.461 0.618 0.2092 1.26 0.51 3.11 0.479 0.403 0.235 0.6294 1.62 0.732 3.56 0.529 0.397 0.182 0.7399 1.7 0.78 3.69 0.109 0.434 0.802 0.09563 1.11 0.476 2.61 PRS_PLINK_0.001 FALSE 529 Diseases and other conditions of the tongue Both 212 2614 10 digestive chartreuse4 2614, 212 654, 50 653, 58 653, 51 654, 53 0.0415 0.0482 0.39 0.409 1.04 0.948 1.15 0.149 0.198 0.452 0.3449 1.16 0.787 1.71 0.0232 0.204 0.909 0.04135 1.02 0.687 1.53 0.0473 0.202 0.815 0.08896 1.05 0.706 1.56 PRS_PLINK_0.001 FALSE 529.1 Glossitis Both 43 650 10 digestive chartreuse4 650, 43 163, 10 162, 9 162, 12 163, 12 0.344 0.511 0.5 0.3007 1.41 0.518 3.84 -0.0786 0.439 0.858 0.06665 0.924 0.391 2.18 0.246 0.415 0.553 0.2573 1.28 0.567 2.88 0.198 0.415 0.633 0.1984 1.22 0.541 2.75 PRS_PLINK_0.001 TRUE 530 Diseases of esophagus Both 6139 60645 10 digestive chartreuse4 60645, 6139 15161, 1437 15161, 1505 15161, 1605 15161, 1592 0.0135 0.0114 0.236 0.6264 1.01 0.991 1.04 0.0483 0.0387 0.211 0.6754 1.05 0.973 1.13 0.111 0.0381 0.00353 2.452 1.12 1.04 1.2 0.103 0.0382 0.00697 2.157 1.11 1.03 1.19 PRS_PLINK_0.001 FALSE 530.1 Esophagitis, GERD and related diseases Both 5742 59059 10 digestive chartreuse4 59059, 5742 14764, 1335 14765, 1410 14764, 1502 14765, 1495 0.0114 0.0119 0.337 0.472 1.01 0.988 1.04 0.0571 0.0399 0.153 0.8163 1.06 0.979 1.14 0.118 0.0394 0.00263 2.58 1.13 1.04 1.22 0.114 0.0394 0.00391 2.408 1.12 1.04 1.21 PRS_PLINK_0.001 FALSE 530.11 GERD Both 4276 48423 10 digestive chartreuse4 48423, 4276 12105, 989 12106, 1068 12105, 1107 12106, 1112 0.0125 0.0137 0.362 0.4418 1.01 0.986 1.04 0.0806 0.046 0.0793 1.101 1.08 0.991 1.19 0.114 0.0456 0.0122 1.912 1.12 1.03 1.23 0.118 0.0455 0.0095 2.022 1.13 1.03 1.23 PRS_PLINK_0.001 FALSE 530.12 Ulcer of esophagus Both 828 10935 10 digestive chartreuse4 10935, 828 2734, 203 2734, 210 2733, 216 2734, 199 0.0122 0.0295 0.678 0.1687 1.01 0.956 1.07 0.0422 0.102 0.679 0.1683 1.04 0.854 1.27 0.0636 0.101 0.529 0.2764 1.07 0.874 1.3 -0.0213 0.103 0.836 0.07755 0.979 0.8 1.2 PRS_PLINK_0.001 FALSE 530.14 Reflux esophagitis Both 1969 22365 10 digestive chartreuse4 22365, 1969 5592, 432 5591, 519 5591, 491 5591, 527 0.0143 0.0189 0.45 0.347 1.01 0.978 1.05 0.19 0.0678 0.00516 2.287 1.21 1.06 1.38 0.132 0.0686 0.0548 1.261 1.14 0.997 1.3 0.2 0.0675 0.0031 2.509 1.22 1.07 1.39 PRS_PLINK_0.001 FALSE 530.2 Esophageal bleeding (varices/hemorrhage) Both 275 3573 10 digestive chartreuse4 3573, 275 894, 56 893, 72 893, 69 893, 78 -0.00902 0.0491 0.854 0.0684 0.991 0.9 1.09 0.282 0.183 0.122 0.9121 1.33 0.927 1.9 0.202 0.184 0.272 0.5657 1.22 0.854 1.75 0.322 0.179 0.0731 1.136 1.38 0.97 1.96 PRS_PLINK_0.001 FALSE 530.3 Stricture and stenosis of esophagus Both 347 3927 10 digestive chartreuse4 3927, 347 982, 97 982, 70 981, 104 982, 76 0.00367 0.047 0.938 0.0279 1 0.915 1.1 -0.333 0.162 0.0397 1.401 0.717 0.522 0.984 0.0634 0.148 0.667 0.1756 1.07 0.798 1.42 -0.235 0.159 0.139 0.8577 0.791 0.58 1.08 PRS_PLINK_0.001 FALSE 530.5 Disorders of esophageal motility Both 119 1378 10 digestive chartreuse4 1378, 119 345, 32 344, 33 344, 28 345, 26 0.0426 0.0524 0.416 0.3811 1.04 0.942 1.16 0.0479 0.255 0.851 0.07007 1.05 0.636 1.73 -0.162 0.265 0.541 0.2667 0.851 0.506 1.43 -0.188 0.27 0.487 0.3126 0.829 0.488 1.41 PRS_PLINK_0.001 FALSE 530.6 Diverticulum of esophagus, acquired Both 21 290 10 digestive chartreuse4 290, 21 73, 4 72, 3 72, 6 73, 8 1.27 0.709 0.0726 1.139 3.57 0.89 14.3 -0.498 0.702 0.478 0.3206 0.608 0.154 2.41 0.573 0.612 0.35 0.4565 1.77 0.534 5.89 0.698 0.594 0.24 0.6191 2.01 0.627 6.44 PRS_PLINK_0.001 TRUE 530.7 Gastroesophageal laceration-hemorrhage syndrome Both 43 725 10 digestive chartreuse4 725, 43 182, 10 181, 12 181, 11 181, 10 0.532 0.517 0.303 0.5185 1.7 0.618 4.69 0.22 0.421 0.6 0.2215 1.25 0.546 2.84 0.178 0.426 0.675 0.1704 1.2 0.519 2.75 0.144 0.437 0.742 0.1294 1.15 0.49 2.72 PRS_PLINK_0.001 TRUE 530.9 Heartburn Both 334 4539 10 digestive chartreuse4 4539, 334 1135, 76 1135, 104 1134, 78 1135, 76 0.0244 0.0458 0.594 0.2262 1.02 0.937 1.12 0.324 0.156 0.0375 1.426 1.38 1.02 1.88 0.0114 0.165 0.945 0.02465 1.01 0.732 1.4 -0.00948 0.166 0.955 0.0202 0.991 0.715 1.37 PRS_PLINK_0.001 FALSE 531 Peptic ulcer (excl. esophageal) Both 1123 14866 10 digestive chartreuse4 14866, 1123 3717, 262 3716, 293 3716, 293 3717, 275 -0.00433 0.0314 0.89 0.05042 0.996 0.936 1.06 0.111 0.0879 0.208 0.6816 1.12 0.94 1.33 0.113 0.088 0.198 0.7044 1.12 0.943 1.33 0.0434 0.0892 0.626 0.2031 1.04 0.877 1.24 PRS_PLINK_0.001 FALSE 531.1 Hemorrhage from gastrointestinal ulcer Both 107 1325 10 digestive chartreuse4 1325, 107 332, 25 331, 40 331, 23 331, 19 -0.000112 0.0874 0.999 0.0004455 1 0.843 1.19 0.481 0.263 0.0676 1.17 1.62 0.966 2.71 -0.0437 0.293 0.881 0.05482 0.957 0.539 1.7 -0.312 0.308 0.311 0.5074 0.732 0.4 1.34 PRS_PLINK_0.001 FALSE 531.2 Gastric ulcer Both 634 8469 10 digestive chartreuse4 8469, 634 2118, 140 2117, 162 2117, 179 2117, 153 0.0181 0.0315 0.565 0.2479 1.02 0.957 1.08 0.14 0.119 0.238 0.6226 1.15 0.911 1.45 0.242 0.117 0.0377 1.423 1.27 1.01 1.6 0.0876 0.12 0.467 0.3305 1.09 0.862 1.38 PRS_PLINK_0.001 FALSE 531.3 Duodenal ulcer Both 483 6261 10 digestive chartreuse4 6261, 483 1566, 120 1565, 114 1565, 117 1565, 132 -0.0245 0.0624 0.694 0.1584 0.976 0.863 1.1 -0.0528 0.135 0.696 0.1577 0.949 0.728 1.24 -0.0222 0.134 0.868 0.06133 0.978 0.752 1.27 0.0929 0.13 0.476 0.3225 1.1 0.85 1.42 PRS_PLINK_0.001 FALSE 531.4 Peptic ulcer, site unspecified Both 51 829 10 digestive chartreuse4 829, 51 208, 13 207, 12 207, 14 207, 12 0.0696 0.435 0.873 0.05909 1.07 0.457 2.51 -0.0948 0.392 0.809 0.09198 0.91 0.422 1.96 0.014 0.382 0.971 0.01291 1.01 0.48 2.14 -0.159 0.399 0.691 0.1608 0.853 0.39 1.86 PRS_PLINK_0.001 FALSE 532 Dysphagia Both 1015 13696 10 digestive chartreuse4 13696, 1015 3423, 229 3424, 280 3424, 257 3424, 249 -0.015 0.0344 0.664 0.178 0.985 0.921 1.05 0.202 0.092 0.0282 1.55 1.22 1.02 1.47 0.116 0.0937 0.215 0.667 1.12 0.935 1.35 0.0854 0.0944 0.366 0.4366 1.09 0.905 1.31 PRS_PLINK_0.001 FALSE 535 Gastritis and duodenitis Both 5028 56210 10 digestive chartreuse4 56210, 5028 14052, 1167 14052, 1281 14052, 1308 14053, 1272 0.0174 0.0122 0.155 0.8097 1.02 0.993 1.04 0.0939 0.0422 0.0261 1.584 1.1 1.01 1.19 0.115 0.042 0.00612 2.213 1.12 1.03 1.22 0.0863 0.0423 0.0411 1.386 1.09 1 1.18 PRS_PLINK_0.001 FALSE 535.1 Acute gastritis Both 211 2441 10 digestive chartreuse4 2441, 211 611, 53 610, 53 610, 49 610, 56 -0.00725 0.0771 0.925 0.03381 0.993 0.854 1.15 0.013 0.201 0.948 0.02306 1.01 0.684 1.5 -0.0746 0.204 0.714 0.1462 0.928 0.622 1.38 0.0496 0.197 0.802 0.09603 1.05 0.714 1.55 PRS_PLINK_0.001 FALSE 535.2 Atrophic gastritis Both 63 738 10 digestive chartreuse4 738, 63 185, 14 184, 13 184, 19 185, 17 0.32 0.439 0.467 0.3311 1.38 0.582 3.25 -0.0572 0.391 0.884 0.05376 0.944 0.439 2.03 0.311 0.358 0.385 0.4148 1.36 0.677 2.75 0.215 0.368 0.559 0.2528 1.24 0.603 2.55 PRS_PLINK_0.001 FALSE 535.6 Duodenitis Both 1376 16069 10 digestive chartreuse4 16069, 1376 4018, 327 4017, 333 4017, 364 4017, 352 0.0096 0.0242 0.692 0.16 1.01 0.963 1.06 0.0211 0.0808 0.794 0.1001 1.02 0.872 1.2 0.114 0.0793 0.15 0.8242 1.12 0.96 1.31 0.0759 0.0799 0.342 0.4659 1.08 0.923 1.26 PRS_PLINK_0.001 FALSE 535.8 Other specified gastritis Both 1489 16975 10 digestive chartreuse4 16975, 1489 4244, 340 4244, 353 4243, 412 4244, 384 0.034 0.021 0.106 0.9755 1.03 0.993 1.08 0.0375 0.0789 0.635 0.1974 1.04 0.889 1.21 0.192 0.0763 0.0121 1.918 1.21 1.04 1.41 0.122 0.0774 0.114 0.9414 1.13 0.971 1.32 PRS_PLINK_0.001 FALSE 535.9 Gastritis and duodenitis, NOS Both 16 212 10 digestive chartreuse4 212, 16 53, 4 53, 5 53, 5 53, 2 -0.408 0.819 0.618 0.2088 0.665 0.134 3.31 0.0305 0.66 0.963 0.01633 1.03 0.283 3.76 0.318 0.625 0.61 0.2144 1.37 0.404 4.68 -0.372 0.732 0.612 0.2135 0.69 0.164 2.89 PRS_PLINK_0.001 TRUE 536.8 Dyspepsia and other specified disorders of function of stomach Both 28 482 10 digestive chartreuse4 482, 28 121, 14 120, 6 120, 7 121, 1 -1.57 0.664 0.0179 1.748 0.207 0.0564 0.762 -0.788 0.468 0.0925 1.034 0.455 0.182 1.14 -0.695 0.459 0.13 0.886 0.499 0.203 1.23 -2.18 0.784 0.00535 2.271 0.113 0.0243 0.524 PRS_PLINK_0.001 TRUE 537 Other disorders of stomach and duodenum Both 573 7171 10 digestive chartreuse4 7171, 573 1793, 152 1793, 141 1792, 145 1793, 135 0.0252 0.032 0.431 0.3652 1.03 0.963 1.09 -0.0723 0.121 0.55 0.2594 0.93 0.734 1.18 -0.0519 0.12 0.667 0.1761 0.949 0.75 1.2 -0.116 0.122 0.343 0.4653 0.89 0.701 1.13 PRS_PLINK_0.001 FALSE 540 Appendiceal conditions Both 648 6696 10 digestive chartreuse4 6696, 648 1674, 174 1674, 171 1674, 160 1674, 143 -0.00739 0.0362 0.838 0.07659 0.993 0.925 1.07 -0.0149 0.113 0.895 0.04833 0.985 0.79 1.23 -0.0782 0.115 0.495 0.3053 0.925 0.739 1.16 -0.181 0.118 0.124 0.9079 0.834 0.662 1.05 PRS_PLINK_0.001 FALSE 540.1 Appendicitis Both 616 6304 10 digestive chartreuse4 6304, 616 1576, 166 1576, 160 1576, 154 1576, 136 -0.00199 0.037 0.957 0.01901 0.998 0.928 1.07 -0.0327 0.116 0.778 0.1091 0.968 0.771 1.21 -0.0676 0.117 0.564 0.2488 0.935 0.743 1.18 -0.184 0.121 0.128 0.8913 0.832 0.657 1.05 PRS_PLINK_0.001 FALSE 540.11 Acute appendicitis Both 540 5606 10 digestive chartreuse4 5606, 540 1402, 153 1401, 138 1401, 130 1402, 119 -0.0391 0.051 0.443 0.3532 0.962 0.87 1.06 -0.102 0.123 0.408 0.3889 0.903 0.71 1.15 -0.16 0.125 0.199 0.7022 0.852 0.667 1.09 -0.248 0.128 0.0519 1.285 0.78 0.608 1 PRS_PLINK_0.001 FALSE 550 Abdominal hernia Both 8645 61515 10 digestive chartreuse4 61515, 8645 15378, 2030 15379, 2251 15378, 2192 15379, 2172 0.00501 0.0108 0.643 0.1918 1.01 0.984 1.03 0.106 0.033 0.00137 2.865 1.11 1.04 1.19 0.0795 0.0332 0.0167 1.777 1.08 1.01 1.16 0.0749 0.0333 0.0244 1.613 1.08 1.01 1.15 PRS_PLINK_0.001 FALSE 550.1 Inguinal hernia Both 3224 26994 10 digestive chartreuse4 26994, 3224 6749, 785 6748, 817 6748, 809 6749, 813 0.00565 0.0178 0.751 0.1246 1.01 0.971 1.04 0.0465 0.053 0.38 0.4199 1.05 0.944 1.16 0.0352 0.0531 0.508 0.2944 1.04 0.933 1.15 0.0448 0.053 0.398 0.4001 1.05 0.943 1.16 PRS_PLINK_0.001 FALSE 550.2 Diaphragmatic hernia Both 4766 51400 10 digestive chartreuse4 51400, 4766 12849, 1119 12850, 1247 12850, 1218 12850, 1182 0.00615 0.0135 0.649 0.1875 1.01 0.98 1.03 0.11 0.0431 0.0104 1.985 1.12 1.03 1.22 0.0866 0.0433 0.0453 1.344 1.09 1 1.19 0.055 0.0435 0.207 0.6841 1.06 0.97 1.15 PRS_PLINK_0.001 FALSE 550.3 Femoral hernia Both 130 1350 10 digestive chartreuse4 1350, 130 338, 44 337, 34 337, 20 338, 32 -0.627 0.295 0.0336 1.474 0.534 0.3 0.952 -0.26 0.238 0.274 0.5615 0.771 0.484 1.23 -0.8 0.276 0.00371 2.431 0.449 0.262 0.771 -0.3 0.242 0.215 0.6673 0.741 0.462 1.19 PRS_PLINK_0.001 FALSE 550.4 Umbilical hernia Both 690 8003 10 digestive chartreuse4 8003, 690 2001, 155 2001, 169 2000, 160 2001, 206 0.035 0.0293 0.233 0.6322 1.04 0.978 1.1 0.09 0.115 0.435 0.3618 1.09 0.873 1.37 0.0419 0.117 0.72 0.1429 1.04 0.83 1.31 0.284 0.111 0.0102 1.991 1.33 1.07 1.65 PRS_PLINK_0.001 FALSE 550.5 Ventral hernia Both 620 7268 10 digestive chartreuse4 7268, 620 1817, 134 1817, 159 1817, 159 1817, 168 0.053 0.04 0.185 0.7327 1.05 0.975 1.14 0.175 0.121 0.15 0.8238 1.19 0.939 1.51 0.182 0.122 0.134 0.873 1.2 0.945 1.52 0.236 0.12 0.0497 1.303 1.27 1 1.6 PRS_PLINK_0.001 FALSE 555 Inflammatory bowel disease and other gastroenteritis and colitis Both 861 9623 10 digestive chartreuse4 9623, 861 2406, 204 2406, 216 2405, 209 2406, 232 -0.00491 0.036 0.892 0.04986 0.995 0.927 1.07 0.0517 0.102 0.611 0.2142 1.05 0.863 1.28 0.0146 0.102 0.887 0.05226 1.01 0.83 1.24 0.122 0.1 0.224 0.6493 1.13 0.928 1.37 PRS_PLINK_0.001 FALSE 555.1 Regional enteritis Both 305 3759 10 digestive chartreuse4 3759, 305 940, 76 940, 74 939, 76 940, 79 0.0147 0.0439 0.737 0.1325 1.01 0.931 1.11 -0.0327 0.168 0.846 0.07284 0.968 0.696 1.35 -0.00681 0.167 0.968 0.01435 0.993 0.716 1.38 0.0224 0.166 0.893 0.04932 1.02 0.739 1.42 PRS_PLINK_0.001 FALSE 555.2 Ulcerative colitis Both 637 6820 10 digestive chartreuse4 6820, 637 1705, 150 1705, 164 1705, 146 1705, 177 -0.0109 0.0519 0.833 0.07943 0.989 0.893 1.09 0.0864 0.118 0.463 0.3345 1.09 0.866 1.37 -0.0298 0.121 0.805 0.09423 0.971 0.766 1.23 0.162 0.116 0.163 0.7887 1.18 0.937 1.47 PRS_PLINK_0.001 FALSE 555.21 Ulcerative colitis (chronic) Both 108 1157 10 digestive chartreuse4 1157, 108 290, 19 289, 32 289, 31 289, 26 0.0589 0.0942 0.532 0.2741 1.06 0.882 1.28 0.505 0.296 0.0877 1.057 1.66 0.928 2.96 0.541 0.3 0.0712 1.148 1.72 0.954 3.09 0.348 0.304 0.252 0.5978 1.42 0.78 2.57 PRS_PLINK_0.001 FALSE 556 Ulceration of the lower GI tract Both 194 2263 10 digestive chartreuse4 2263, 194 566, 46 566, 47 565, 47 566, 54 0.0463 0.088 0.599 0.2228 1.05 0.881 1.24 0.0602 0.214 0.778 0.1088 1.06 0.698 1.62 0.00685 0.214 0.974 0.01126 1.01 0.662 1.53 0.153 0.208 0.462 0.3351 1.17 0.775 1.75 PRS_PLINK_0.001 FALSE 556.1 Ulceration of intestine Both 119 1418 10 digestive chartreuse4 1418, 119 355, 30 354, 28 354, 32 355, 29 0.0634 0.112 0.57 0.244 1.07 0.856 1.33 -0.0249 0.269 0.926 0.0333 0.975 0.576 1.65 0.0411 0.26 0.875 0.05823 1.04 0.626 1.73 -0.0127 0.266 0.962 0.01686 0.987 0.586 1.66 PRS_PLINK_0.001 FALSE 557 Intestinal malabsorption (non-celiac) Both 82 648 10 digestive chartreuse4 648, 82 162, 31 162, 17 162, 18 162, 16 -0.947 0.358 0.00819 2.087 0.388 0.192 0.783 -0.543 0.317 0.0868 1.062 0.581 0.312 1.08 -0.5 0.313 0.111 0.9565 0.607 0.328 1.12 -0.703 0.329 0.0325 1.487 0.495 0.26 0.943 PRS_PLINK_0.001 FALSE 557.1 Celiac disease Both 420 4010 10 digestive chartreuse4 4010, 420 1003, 99 1002, 103 1002, 105 1003, 112 -0.0126 0.0626 0.84 0.07567 0.987 0.873 1.12 0.0492 0.147 0.738 0.1319 1.05 0.787 1.4 0.0719 0.147 0.624 0.205 1.07 0.806 1.43 0.12 0.144 0.406 0.3916 1.13 0.85 1.5 PRS_PLINK_0.001 FALSE 558 Noninfectious gastroenteritis Both 2742 33552 10 digestive chartreuse4 33552, 2742 8388, 668 8388, 711 8388, 703 8388, 660 0.0155 0.0171 0.365 0.4381 1.02 0.982 1.05 0.0626 0.056 0.263 0.5793 1.06 0.954 1.19 0.0517 0.0562 0.358 0.4466 1.05 0.943 1.18 -0.0152 0.057 0.79 0.1024 0.985 0.881 1.1 PRS_PLINK_0.001 FALSE 559 Ileostomy status Both 291 3523 10 digestive chartreuse4 3523, 291 881, 71 881, 75 880, 69 881, 76 0.0469 0.0464 0.313 0.5047 1.05 0.957 1.15 0.0604 0.171 0.724 0.1403 1.06 0.76 1.49 -0.0416 0.175 0.812 0.09069 0.959 0.681 1.35 0.0582 0.171 0.733 0.1348 1.06 0.759 1.48 PRS_PLINK_0.001 FALSE 560 Intestinal obstruction without mention of hernia Both 659 8375 10 digestive chartreuse4 8375, 659 2094, 160 2094, 146 2093, 177 2094, 176 0.0333 0.0326 0.307 0.5128 1.03 0.97 1.1 -0.0973 0.118 0.41 0.3875 0.907 0.72 1.14 0.0995 0.113 0.379 0.4215 1.1 0.885 1.38 0.0914 0.113 0.42 0.3771 1.1 0.878 1.37 PRS_PLINK_0.001 FALSE 560.1 Paralytic ileus Both 96 1048 10 digestive chartreuse4 1048, 96 262, 19 262, 24 262, 29 262, 24 0.0223 0.0834 0.789 0.103 1.02 0.868 1.2 0.2 0.313 0.523 0.2815 1.22 0.662 2.25 0.419 0.301 0.164 0.7843 1.52 0.842 2.74 0.189 0.311 0.544 0.2645 1.21 0.657 2.22 PRS_PLINK_0.001 FALSE 560.2 Impaction of intestine Both 35 552 10 digestive chartreuse4 552, 35 138, 9 138, 8 138, 8 138, 10 0.0544 0.0914 0.552 0.2584 1.06 0.883 1.26 0.035 0.475 0.941 0.02629 1.04 0.408 2.63 -0.0493 0.473 0.917 0.03765 0.952 0.377 2.4 0.142 0.447 0.751 0.1245 1.15 0.48 2.77 PRS_PLINK_0.001 TRUE 560.3 Peritoneal or intestinal adhesions Both 135 1797 10 digestive chartreuse4 1797, 135 450, 39 449, 25 449, 37 449, 34 0.115 0.0481 0.0169 1.771 1.12 1.02 1.23 -0.399 0.26 0.125 0.9044 0.671 0.404 1.12 -0.0411 0.235 0.861 0.06475 0.96 0.605 1.52 -0.105 0.241 0.663 0.1782 0.9 0.562 1.44 PRS_PLINK_0.001 FALSE 560.4 Other intestinal obstruction Both 565 7166 10 digestive chartreuse4 7166, 565 1792, 138 1791, 130 1791, 146 1792, 151 0.0353 0.0337 0.294 0.5311 1.04 0.97 1.11 -0.0644 0.126 0.609 0.2151 0.938 0.732 1.2 0.0486 0.123 0.692 0.1597 1.05 0.825 1.34 0.0828 0.122 0.498 0.3031 1.09 0.855 1.38 PRS_PLINK_0.001 FALSE 561 Symptoms involving digestive system Both 3026 34265 10 digestive chartreuse4 34265, 3026 8567, 767 8566, 727 8566, 782 8566, 750 0.0156 0.0155 0.313 0.5042 1.02 0.985 1.05 -0.0527 0.0539 0.329 0.483 0.949 0.854 1.05 0.0208 0.053 0.695 0.1583 1.02 0.92 1.13 -0.0214 0.0535 0.69 0.1613 0.979 0.881 1.09 PRS_PLINK_0.001 FALSE 561.1 Diarrhea Both 88 987 10 digestive chartreuse4 987, 88 247, 24 247, 26 246, 11 247, 27 0.00872 0.0683 0.898 0.04651 1.01 0.882 1.15 0.112 0.29 0.699 0.1554 1.12 0.634 1.97 -0.746 0.357 0.0369 1.433 0.474 0.236 0.956 0.102 0.287 0.721 0.1419 1.11 0.631 1.94 PRS_PLINK_0.001 FALSE 561.2 Flatulence Both 286 3635 10 digestive chartreuse4 3635, 286 909, 67 909, 71 908, 72 909, 76 -0.00228 0.0541 0.966 0.01485 0.998 0.897 1.11 0.0574 0.175 0.742 0.1293 1.06 0.752 1.49 0.0728 0.174 0.676 0.1699 1.08 0.764 1.51 0.128 0.172 0.458 0.3388 1.14 0.811 1.59 PRS_PLINK_0.001 FALSE 562 Diverticulosis and diverticulitis Both 5013 46165 10 digestive chartreuse4 46165, 5013 11542, 1214 11541, 1286 11541, 1236 11541, 1277 0.00995 0.0134 0.458 0.339 1.01 0.984 1.04 0.059 0.0422 0.162 0.7909 1.06 0.977 1.15 0.0171 0.0426 0.688 0.1622 1.02 0.936 1.11 0.0508 0.0423 0.23 0.638 1.05 0.968 1.14 PRS_PLINK_0.001 FALSE 562.1 Diverticulosis Both 5007 46157 10 digestive chartreuse4 46157, 5007 11540, 1212 11539, 1285 11539, 1235 11539, 1275 0.00991 0.0134 0.461 0.3366 1.01 0.984 1.04 0.0599 0.0422 0.156 0.8076 1.06 0.977 1.15 0.018 0.0426 0.673 0.1718 1.02 0.937 1.11 0.0509 0.0424 0.23 0.6384 1.05 0.968 1.14 PRS_PLINK_0.001 FALSE 563 Constipation Both 1672 22030 10 digestive chartreuse4 22030, 1672 5508, 402 5507, 405 5507, 438 5508, 427 0.00518 0.0232 0.824 0.08422 1.01 0.96 1.05 0.0074 0.0728 0.919 0.03668 1.01 0.873 1.16 0.0882 0.0716 0.218 0.6618 1.09 0.949 1.26 0.0617 0.072 0.391 0.4076 1.06 0.924 1.22 PRS_PLINK_0.001 FALSE 564 Functional digestive disorders Both 3807 45739 10 digestive chartreuse4 45739, 3807 11435, 973 11435, 940 11434, 948 11435, 946 -0.00855 0.0176 0.627 0.203 0.991 0.958 1.03 -0.0356 0.0476 0.454 0.3426 0.965 0.879 1.06 -0.0251 0.0475 0.598 0.2235 0.975 0.889 1.07 -0.0304 0.0475 0.522 0.282 0.97 0.884 1.06 PRS_PLINK_0.001 FALSE 564.1 Irritable Bowel Syndrome Both 927 12007 10 digestive chartreuse4 12007, 927 3002, 222 3002, 228 3001, 234 3002, 243 -0.00546 0.0352 0.877 0.05716 0.995 0.928 1.07 0.024 0.0975 0.805 0.09403 1.02 0.846 1.24 0.0526 0.0969 0.587 0.2313 1.05 0.872 1.27 0.089 0.0961 0.354 0.4505 1.09 0.905 1.32 PRS_PLINK_0.001 FALSE 564.8 Abnormal findings on exam of gastrointestinal tract/ abdominal area Both 278 3497 10 digestive chartreuse4 3497, 278 875, 70 874, 61 874, 77 874, 70 -0.0146 0.0754 0.847 0.07231 0.986 0.85 1.14 -0.122 0.18 0.496 0.3042 0.885 0.622 1.26 0.101 0.17 0.554 0.2568 1.11 0.792 1.54 0.00446 0.174 0.98 0.008959 1 0.714 1.41 PRS_PLINK_0.001 FALSE 564.9 Personal history of diseases of digestive system Both 2689 32540 10 digestive chartreuse4 32540, 2689 8135, 699 8135, 678 8135, 657 8135, 655 -0.0019 0.0196 0.923 0.03496 0.998 0.961 1.04 -0.0302 0.0561 0.59 0.2291 0.97 0.869 1.08 -0.0593 0.0565 0.294 0.5315 0.942 0.844 1.05 -0.0676 0.0566 0.232 0.6342 0.935 0.837 1.04 PRS_PLINK_0.001 FALSE 565 Anal and rectal conditions Both 2840 31383 10 digestive chartreuse4 31383, 2840 7845, 735 7846, 668 7845, 708 7846, 729 -0.000195 0.0195 0.992 0.003478 1 0.962 1.04 -0.0966 0.0558 0.0831 1.08 0.908 0.814 1.01 -0.0394 0.055 0.474 0.3242 0.961 0.863 1.07 -0.00953 0.0546 0.861 0.06476 0.991 0.89 1.1 PRS_PLINK_0.001 FALSE 565.1 Anal and rectal polyp Both 1412 15524 10 digestive chartreuse4 15524, 1412 3880, 350 3881, 352 3881, 338 3881, 372 -0.0142 0.0304 0.641 0.1934 0.986 0.929 1.05 0.000489 0.0787 0.995 0.002157 1 0.857 1.17 -0.0376 0.0794 0.636 0.1968 0.963 0.824 1.13 0.0546 0.0778 0.483 0.3162 1.06 0.907 1.23 PRS_PLINK_0.001 FALSE 567 Peritonitis and retroperitoneal infections Both 152 1943 10 digestive chartreuse4 1943, 152 486, 40 486, 41 485, 33 486, 38 -0.00482 0.0827 0.954 0.02065 0.995 0.846 1.17 0.0131 0.229 0.955 0.02022 1.01 0.646 1.59 -0.196 0.24 0.413 0.3844 0.822 0.514 1.31 -0.0921 0.232 0.692 0.1601 0.912 0.578 1.44 PRS_PLINK_0.001 FALSE 568 Other disorders of peritoneum Both 579 6909 10 digestive chartreuse4 6909, 579 1728, 151 1727, 136 1727, 153 1727, 139 0.0165 0.033 0.617 0.2096 1.02 0.953 1.08 -0.0936 0.123 0.445 0.3516 0.911 0.716 1.16 0.0328 0.119 0.784 0.1058 1.03 0.818 1.31 -0.0606 0.122 0.62 0.2079 0.941 0.741 1.2 PRS_PLINK_0.001 FALSE 568.1 Peritoneal adhesions (postoperative) (postinfection) Both 547 6613 10 digestive chartreuse4 6613, 547 1654, 142 1653, 127 1653, 143 1653, 135 0.0196 0.0334 0.557 0.2544 1.02 0.955 1.09 -0.0952 0.126 0.451 0.3454 0.909 0.71 1.16 0.0275 0.123 0.823 0.08438 1.03 0.807 1.31 -0.0242 0.125 0.846 0.07254 0.976 0.764 1.25 PRS_PLINK_0.001 FALSE 569 Other disorders of intestine Both 736 8765 10 digestive chartreuse4 8765, 736 2192, 167 2191, 177 2191, 197 2191, 195 0.0133 0.0362 0.712 0.1474 1.01 0.944 1.09 0.0558 0.112 0.617 0.2098 1.06 0.85 1.32 0.157 0.109 0.15 0.8237 1.17 0.945 1.45 0.147 0.109 0.179 0.7475 1.16 0.935 1.44 PRS_PLINK_0.001 FALSE 569.1 Toxic gastroenteritis and colitis Both 19 319 10 digestive chartreuse4 319, 19 80, 2 80, 4 79, 8 80, 5 0.0889 0.0953 0.351 0.4548 1.09 0.907 1.32 0.475 0.743 0.523 0.2818 1.61 0.375 6.89 1.12 0.706 0.113 0.9464 3.06 0.767 12.2 0.688 0.73 0.346 0.4613 1.99 0.476 8.32 PRS_PLINK_0.001 TRUE 569.2 Gastrointestinal complications Both 89 1039 10 digestive chartreuse4 1039, 89 260, 21 260, 25 259, 19 260, 24 0.0801 0.0939 0.393 0.4052 1.08 0.901 1.3 0.106 0.302 0.725 0.1394 1.11 0.615 2.01 -0.103 0.321 0.749 0.1254 0.903 0.481 1.69 0.0931 0.303 0.758 0.1202 1.1 0.607 1.99 PRS_PLINK_0.001 FALSE 571 Chronic liver disease and cirrhosis Both 448 6205 10 digestive chartreuse4 6205, 448 1551, 113 1551, 109 1551, 114 1551, 112 -0.0347 0.0596 0.561 0.2511 0.966 0.859 1.09 -0.038 0.138 0.783 0.1063 0.963 0.734 1.26 0.00714 0.137 0.958 0.01845 1.01 0.77 1.32 -0.0108 0.137 0.938 0.02802 0.989 0.756 1.29 PRS_PLINK_0.001 FALSE 571.5 Other chronic nonalcoholic liver disease Both 266 3587 10 digestive chartreuse4 3587, 266 897, 63 897, 66 896, 70 897, 67 0.0116 0.0592 0.845 0.07318 1.01 0.901 1.14 0.0563 0.18 0.755 0.122 1.06 0.743 1.51 0.0754 0.179 0.673 0.1717 1.08 0.759 1.53 0.066 0.18 0.713 0.1469 1.07 0.751 1.52 PRS_PLINK_0.001 FALSE 571.51 Cirrhosis of liver without mention of alcohol Both 23 221 10 digestive chartreuse4 221, 23 56, 5 55, 6 55, 5 55, 7 0.392 0.782 0.616 0.2104 1.48 0.319 6.86 0.102 0.594 0.864 0.06366 1.11 0.345 3.55 -0.16 0.625 0.798 0.09794 0.852 0.251 2.9 0.325 0.574 0.572 0.2429 1.38 0.449 4.26 PRS_PLINK_0.001 TRUE 571.6 Primary biliary cirrhosis Both 45 526 10 digestive chartreuse4 526, 45 132, 11 131, 7 131, 16 132, 11 0.23 0.492 0.639 0.1943 1.26 0.48 3.3 -0.408 0.464 0.379 0.4211 0.665 0.268 1.65 0.349 0.39 0.371 0.4306 1.42 0.66 3.04 0.106 0.424 0.802 0.09575 1.11 0.485 2.55 PRS_PLINK_0.001 TRUE 571.8 Liver abscess and sequelae of chronic liver disease Both 135 2036 10 digestive chartreuse4 2036, 135 509, 34 509, 35 509, 31 509, 35 0.0104 0.0798 0.896 0.04767 1.01 0.864 1.18 0.0204 0.244 0.933 0.03002 1.02 0.633 1.65 -0.0564 0.252 0.823 0.08469 0.945 0.577 1.55 0.0442 0.244 0.856 0.06728 1.05 0.648 1.69 PRS_PLINK_0.001 FALSE 571.81 Portal hypertension Both 74 1152 10 digestive chartreuse4 1152, 74 288, 16 288, 21 288, 14 288, 23 0.0363 0.0735 0.621 0.207 1.04 0.898 1.2 0.254 0.328 0.438 0.3582 1.29 0.678 2.45 -0.0972 0.359 0.786 0.1043 0.907 0.449 1.83 0.353 0.325 0.277 0.5568 1.42 0.753 2.69 PRS_PLINK_0.001 FALSE 572 Ascites (non malignant) Both 235 3260 10 digestive chartreuse4 3260, 235 815, 50 815, 51 815, 70 815, 64 0.0444 0.0692 0.521 0.283 1.05 0.913 1.2 0.0168 0.202 0.934 0.02988 1.02 0.685 1.51 0.323 0.189 0.0886 1.052 1.38 0.952 2 0.229 0.193 0.235 0.6287 1.26 0.862 1.83 PRS_PLINK_0.001 FALSE 573 Other disorders of liver Both 252 3180 10 digestive chartreuse4 3180, 252 795, 62 795, 71 795, 61 795, 58 -0.0254 0.0675 0.706 0.151 0.975 0.854 1.11 0.145 0.179 0.417 0.3794 1.16 0.814 1.64 -0.0251 0.185 0.892 0.04941 0.975 0.678 1.4 -0.0638 0.187 0.734 0.1346 0.938 0.65 1.35 PRS_PLINK_0.001 FALSE 573.2 Liver replaced by transplant Both 20 214 10 digestive chartreuse4 214, 20 54, 3 53, 7 53, 6 54, 4 -0.206 0.798 0.796 0.09907 0.814 0.17 3.89 0.566 0.634 0.372 0.4289 1.76 0.508 6.1 0.326 0.712 0.647 0.1889 1.38 0.343 5.59 -0.287 0.73 0.694 0.1583 0.751 0.18 3.14 PRS_PLINK_0.001 TRUE 573.3 Hepatomegaly Both 40 639 10 digestive chartreuse4 639, 40 160, 9 160, 11 159, 7 160, 13 0.337 0.524 0.52 0.2838 1.4 0.502 3.91 0.134 0.436 0.758 0.1201 1.14 0.487 2.69 -0.156 0.483 0.746 0.1271 0.855 0.332 2.2 0.32 0.419 0.445 0.3518 1.38 0.606 3.13 PRS_PLINK_0.001 TRUE 573.5 Jaundice (not of newborn) Both 145 1848 10 digestive chartreuse4 1848, 145 462, 43 462, 33 462, 28 462, 41 0.0891 0.0425 0.0361 1.442 1.09 1.01 1.19 -0.284 0.237 0.231 0.6366 0.753 0.474 1.2 -0.427 0.246 0.0831 1.08 0.652 0.402 1.06 -0.0462 0.226 0.838 0.07685 0.955 0.614 1.49 PRS_PLINK_0.001 FALSE 573.7 Abnormal results of function study of liver Both 614 7268 10 digestive chartreuse4 7268, 614 1817, 141 1817, 152 1817, 162 1817, 159 -0.00152 0.0415 0.971 0.01292 0.998 0.921 1.08 0.0689 0.121 0.569 0.2448 1.07 0.845 1.36 0.153 0.119 0.202 0.6953 1.16 0.922 1.47 0.131 0.12 0.275 0.5608 1.14 0.901 1.44 PRS_PLINK_0.001 FALSE 573.9 Abnormal serum enzyme levels Both 34 455 10 digestive chartreuse4 455, 34 114, 5 114, 13 113, 3 114, 13 0.505 0.451 0.262 0.5816 1.66 0.685 4.01 0.866 0.506 0.087 1.061 2.38 0.882 6.41 -0.647 0.658 0.325 0.488 0.524 0.144 1.9 0.843 0.509 0.0976 1.011 2.32 0.857 6.3 PRS_PLINK_0.001 TRUE 574 Cholelithiasis and cholecystitis Both 2924 32861 10 digestive chartreuse4 32861, 2924 8215, 706 8215, 748 8215, 758 8215, 712 0.0176 0.0157 0.263 0.5803 1.02 0.987 1.05 0.0551 0.0547 0.314 0.5036 1.06 0.949 1.18 0.0708 0.0545 0.194 0.7117 1.07 0.965 1.19 0.00816 0.0553 0.883 0.05415 1.01 0.905 1.12 PRS_PLINK_0.001 FALSE 574.1 Cholelithiasis Both 2529 28436 10 digestive chartreuse4 28436, 2529 7108, 611 7109, 653 7109, 639 7109, 626 0.023 0.0158 0.145 0.8385 1.02 0.992 1.06 0.0629 0.0587 0.284 0.5473 1.06 0.949 1.19 0.0439 0.059 0.456 0.3407 1.04 0.931 1.17 0.0236 0.0592 0.69 0.1611 1.02 0.912 1.15 PRS_PLINK_0.001 FALSE 574.11 Cholelithiasis with acute cholecystitis Both 252 3137 10 digestive chartreuse4 3137, 252 785, 61 784, 77 784, 59 784, 55 0.0318 0.0531 0.549 0.2606 1.03 0.93 1.15 0.241 0.177 0.173 0.7621 1.27 0.9 1.8 -0.0167 0.188 0.929 0.03205 0.983 0.681 1.42 -0.111 0.19 0.558 0.2533 0.895 0.616 1.3 PRS_PLINK_0.001 FALSE 574.12 Cholelithiasis with other cholecystitis Both 1033 11557 10 digestive chartreuse4 11557, 1033 2890, 268 2889, 270 2889, 251 2889, 244 0.0166 0.0257 0.519 0.2847 1.02 0.967 1.07 0.00362 0.09 0.968 0.01416 1 0.841 1.2 -0.0715 0.0916 0.435 0.3618 0.931 0.778 1.11 -0.0958 0.0922 0.299 0.5249 0.909 0.758 1.09 PRS_PLINK_0.001 FALSE 574.2 Calculus of bile duct Both 460 5371 10 digestive chartreuse4 5371, 460 1343, 119 1343, 109 1342, 115 1343, 117 0.0236 0.0437 0.59 0.2295 1.02 0.94 1.12 -0.0871 0.137 0.526 0.2791 0.917 0.7 1.2 -0.0312 0.136 0.818 0.08716 0.969 0.743 1.26 -0.0137 0.135 0.919 0.03652 0.986 0.757 1.29 PRS_PLINK_0.001 FALSE 574.3 Cholecystitis without cholelithiasis Both 482 5853 10 digestive chartreuse4 5853, 482 1464, 107 1463, 123 1463, 136 1463, 116 0.0426 0.0453 0.346 0.4607 1.04 0.955 1.14 0.129 0.137 0.343 0.4648 1.14 0.871 1.49 0.241 0.134 0.0715 1.146 1.27 0.979 1.65 0.0765 0.138 0.58 0.2368 1.08 0.823 1.42 PRS_PLINK_0.001 FALSE 575 Other biliary tract disease Both 701 8051 10 digestive chartreuse4 8051, 701 2013, 184 2013, 188 2012, 154 2013, 175 -0.0263 0.0448 0.558 0.2538 0.974 0.892 1.06 0.0125 0.108 0.908 0.04205 1.01 0.819 1.25 -0.183 0.113 0.106 0.9744 0.833 0.667 1.04 -0.0563 0.11 0.608 0.2159 0.945 0.762 1.17 PRS_PLINK_0.001 FALSE 575.1 Cholangitis Both 81 1004 10 digestive chartreuse4 1004, 81 251, 17 251, 22 251, 22 251, 20 0.00419 0.0789 0.958 0.0188 1 0.86 1.17 0.24 0.326 0.461 0.3362 1.27 0.671 2.41 0.273 0.324 0.399 0.399 1.31 0.696 2.48 0.263 0.333 0.43 0.3668 1.3 0.677 2.5 PRS_PLINK_0.001 FALSE 575.2 Obstruction of bile duct Both 135 1581 10 digestive chartreuse4 1581, 135 396, 41 395, 32 395, 30 395, 32 -0.475 0.306 0.121 0.9176 0.622 0.341 1.13 -0.244 0.243 0.315 0.5021 0.783 0.486 1.26 -0.327 0.247 0.185 0.7332 0.721 0.444 1.17 -0.26 0.243 0.283 0.5475 0.771 0.479 1.24 PRS_PLINK_0.001 FALSE 575.6 Cholesterolosis of gallbladder Both 82 972 10 digestive chartreuse4 972, 82 243, 18 243, 16 243, 27 243, 21 0.0402 0.0893 0.652 0.1855 1.04 0.874 1.24 -0.0606 0.345 0.86 0.06526 0.941 0.479 1.85 0.392 0.31 0.207 0.6849 1.48 0.806 2.72 0.24 0.33 0.466 0.3314 1.27 0.666 2.43 PRS_PLINK_0.001 FALSE 575.7 Other disorders of gallbladder Both 261 2979 10 digestive chartreuse4 2979, 261 745, 62 745, 84 744, 54 745, 61 -0.0299 0.0756 0.693 0.1594 0.971 0.837 1.13 0.294 0.174 0.091 1.041 1.34 0.954 1.89 -0.149 0.192 0.436 0.36 0.862 0.592 1.25 -0.0197 0.186 0.915 0.03839 0.98 0.681 1.41 PRS_PLINK_0.001 FALSE 575.8 Other disorders of biliary tract Both 187 2096 10 digestive chartreuse4 2096, 187 524, 59 524, 45 524, 39 524, 44 0.0615 0.0554 0.267 0.5737 1.06 0.954 1.19 -0.292 0.206 0.157 0.8033 0.747 0.499 1.12 -0.422 0.213 0.0479 1.32 0.655 0.431 0.996 -0.285 0.206 0.167 0.7771 0.752 0.502 1.13 PRS_PLINK_0.001 FALSE 575.9 Nonspecific abnormal findings on radiological and other examination of biliary tract Both 51 688 10 digestive chartreuse4 688, 51 172, 21 172, 11 172, 7 172, 12 -1.04 0.486 0.0322 1.492 0.353 0.136 0.915 -0.676 0.383 0.0775 1.111 0.508 0.24 1.08 -1.02 0.423 0.0156 1.807 0.36 0.157 0.824 -0.586 0.368 0.111 0.9541 0.557 0.271 1.14 PRS_PLINK_0.001 FALSE 577 Diseases of pancreas Both 451 5533 10 digestive chartreuse4 5533, 451 1384, 99 1383, 116 1383, 127 1383, 109 0.0287 0.0322 0.373 0.4282 1.03 0.966 1.1 0.16 0.141 0.255 0.5932 1.17 0.891 1.55 0.253 0.139 0.0679 1.168 1.29 0.982 1.69 0.0968 0.143 0.499 0.3021 1.1 0.832 1.46 PRS_PLINK_0.001 FALSE 577.1 Acute pancreatitis Both 359 4097 10 digestive chartreuse4 4097, 359 1025, 74 1024, 93 1024, 106 1024, 86 0.0443 0.0341 0.193 0.7138 1.05 0.978 1.12 0.228 0.161 0.156 0.8075 1.26 0.917 1.72 0.387 0.157 0.0138 1.86 1.47 1.08 2.01 0.152 0.163 0.352 0.4536 1.16 0.845 1.6 PRS_PLINK_0.001 FALSE 577.2 Chronic pancreatitis Both 79 1075 10 digestive chartreuse4 1075, 79 269, 20 269, 26 268, 16 269, 17 -0.346 0.38 0.362 0.4408 0.707 0.336 1.49 0.218 0.3 0.469 0.3292 1.24 0.69 2.24 -0.203 0.332 0.542 0.2661 0.817 0.426 1.57 -0.153 0.329 0.641 0.1932 0.858 0.451 1.63 PRS_PLINK_0.001 FALSE 577.3 Cyst and pseudocyst of pancreas Both 61 779 10 digestive chartreuse4 779, 61 195, 18 195, 15 194, 14 195, 14 0.0612 0.0504 0.225 0.6485 1.06 0.963 1.17 -0.185 0.35 0.598 0.2234 0.831 0.419 1.65 -0.387 0.364 0.287 0.5415 0.679 0.333 1.39 -0.3 0.357 0.4 0.3977 0.741 0.368 1.49 PRS_PLINK_0.001 FALSE 578 Gastrointestinal hemorrhage Both 3721 44207 10 digestive chartreuse4 44207, 3721 11052, 922 11052, 916 11051, 944 11052, 939 -0.0132 0.018 0.463 0.3343 0.987 0.953 1.02 -0.00545 0.0485 0.911 0.04071 0.995 0.904 1.09 0.0245 0.0482 0.611 0.2142 1.02 0.932 1.13 0.0173 0.0483 0.72 0.1428 1.02 0.926 1.12 PRS_PLINK_0.001 FALSE 578.1 Hematemesis Both 270 4134 10 digestive chartreuse4 4134, 270 1034, 61 1033, 73 1033, 75 1034, 61 -0.0312 0.0758 0.68 0.1672 0.969 0.835 1.12 0.186 0.177 0.293 0.5328 1.2 0.851 1.7 0.195 0.176 0.268 0.5725 1.22 0.861 1.72 0.0182 0.184 0.921 0.03555 1.02 0.71 1.46 PRS_PLINK_0.001 FALSE 578.2 Blood in stool Both 379 5428 10 digestive chartreuse4 5428, 379 1357, 90 1357, 88 1357, 105 1357, 96 -0.0361 0.063 0.567 0.2467 0.965 0.853 1.09 -0.0283 0.153 0.854 0.06868 0.972 0.72 1.31 0.165 0.148 0.264 0.578 1.18 0.883 1.58 0.0583 0.15 0.698 0.156 1.06 0.789 1.42 PRS_PLINK_0.001 FALSE 578.8 Hemorrhage of rectum and anus Both 2443 28081 10 digestive chartreuse4 28081, 2443 7021, 609 7020, 581 7020, 626 7020, 627 0.000156 0.0195 0.994 0.002783 1 0.963 1.04 -0.0464 0.0604 0.442 0.3546 0.955 0.848 1.07 0.0283 0.0593 0.633 0.1984 1.03 0.916 1.16 0.0307 0.0593 0.605 0.2184 1.03 0.918 1.16 PRS_PLINK_0.001 FALSE 578.9 Hemorrhage of gastrointestinal tract Both 944 11263 10 digestive chartreuse4 11263, 944 2816, 236 2816, 249 2815, 235 2816, 224 -0.00814 0.0357 0.82 0.08635 0.992 0.925 1.06 0.0513 0.0944 0.587 0.2313 1.05 0.875 1.27 -0.00507 0.0957 0.958 0.01876 0.995 0.825 1.2 -0.0573 0.0968 0.554 0.2565 0.944 0.781 1.14 PRS_PLINK_0.001 FALSE 579 Other symptoms involving abdomen and pelvis Both 277 3301 10 digestive chartreuse4 3301, 277 826, 70 825, 61 825, 80 825, 66 0.063 0.0367 0.0859 1.066 1.07 0.991 1.14 -0.108 0.18 0.548 0.2615 0.897 0.63 1.28 0.118 0.17 0.489 0.3109 1.12 0.806 1.57 -0.0577 0.177 0.744 0.1285 0.944 0.668 1.33 PRS_PLINK_0.001 FALSE 579.2 Splenomegaly Both 80 927 10 digestive chartreuse4 927, 80 232, 15 232, 20 231, 24 232, 21 0.124 0.0725 0.0876 1.058 1.13 0.982 1.3 0.293 0.342 0.391 0.4077 1.34 0.686 2.62 0.395 0.334 0.238 0.6238 1.48 0.771 2.86 0.327 0.336 0.33 0.4815 1.39 0.718 2.68 PRS_PLINK_0.001 FALSE 579.8 Nonspecific abnormal findings in stool contents Both 316 3582 10 digestive chartreuse4 3582, 316 896, 78 895, 73 895, 84 896, 81 0.0226 0.0378 0.55 0.2596 1.02 0.95 1.1 -0.0731 0.168 0.664 0.1777 0.93 0.668 1.29 0.0579 0.163 0.723 0.141 1.06 0.77 1.46 0.0341 0.164 0.835 0.07808 1.03 0.75 1.43 PRS_PLINK_0.001 FALSE 580 Nephritis; nephrosis; renal sclerosis Both 209 3191 11 genitourinary black 3191, 209 798, 53 798, 36 797, 57 798, 63 -0.00206 0.0617 0.973 0.01173 0.998 0.884 1.13 -0.383 0.218 0.0785 1.105 0.682 0.445 1.04 0.0742 0.195 0.703 0.1531 1.08 0.736 1.58 0.176 0.191 0.357 0.4474 1.19 0.82 1.73 PRS_PLINK_0.001 FALSE 580.1 Glomerulonephritis Both 142 2213 11 genitourinary black 2213, 142 554, 34 553, 27 553, 38 553, 43 0.0167 0.0637 0.793 0.1007 1.02 0.897 1.15 -0.224 0.259 0.385 0.414 0.799 0.481 1.33 0.108 0.239 0.652 0.1857 1.11 0.697 1.78 0.244 0.233 0.295 0.5299 1.28 0.808 2.02 PRS_PLINK_0.001 FALSE 580.11 Proliferative glomerulonephritis Both 9 177 11 genitourinary black 177, 9 45, 1 44, 1 44, 2 44, 5 0.0704 0.119 0.553 0.2573 1.07 0.85 1.35 0.285 0.938 0.761 0.1187 1.33 0.212 8.37 0.692 0.993 0.486 0.3131 2 0.285 14 1.02 0.841 0.223 0.6511 2.78 0.536 14.5 PRS_PLINK_0.001 TRUE 580.12 Non-proliferative glomerulonephritis Both 21 284 11 genitourinary black 284, 21 71, 6 71, 2 71, 5 71, 8 0.721 0.696 0.3 0.5227 2.06 0.526 8.05 -0.955 0.708 0.177 0.7512 0.385 0.0962 1.54 -0.0471 0.649 0.942 0.02591 0.954 0.267 3.4 -0.0805 0.553 0.884 0.05339 0.923 0.312 2.73 PRS_PLINK_0.001 TRUE 580.14 Chronic glomerulonephritis, NOS Both 117 1817 11 genitourinary black 1817, 117 455, 27 454, 25 454, 30 454, 35 0.0254 0.071 0.72 0.1425 1.03 0.893 1.18 -0.0573 0.279 0.837 0.07715 0.944 0.547 1.63 0.111 0.267 0.678 0.1688 1.12 0.662 1.89 0.283 0.259 0.275 0.5613 1.33 0.799 2.2 PRS_PLINK_0.001 FALSE 580.2 Nephrotic syndrome without mention of glomerulonephritis Both 62 953 11 genitourinary black 953, 62 239, 13 238, 12 238, 18 238, 19 0.0444 0.0944 0.638 0.1952 1.05 0.869 1.26 -0.0915 0.388 0.813 0.08975 0.913 0.427 1.95 0.31 0.359 0.388 0.4111 1.36 0.674 2.76 0.3 0.356 0.4 0.3978 1.35 0.671 2.71 PRS_PLINK_0.001 FALSE 580.3 Nephritis and nephropathy without mention of glomerulonephritis Both 39 525 11 genitourinary black 525, 39 132, 9 131, 10 131, 9 131, 11 -2.19 0.491 8.29e-06 5.082 0.112 0.0429 0.294 0.148 0.447 0.741 0.13 1.16 0.483 2.78 0.0581 0.457 0.899 0.04633 1.06 0.433 2.59 0.18 0.442 0.684 0.1646 1.2 0.503 2.85 PRS_PLINK_0.001 TRUE 580.32 Nephritis and nephropathy with pathological lesion Both 40 551 11 genitourinary black 551, 40 138, 9 138, 10 137, 10 138, 11 0.0676 0.116 0.558 0.2533 1.07 0.853 1.34 0.134 0.443 0.762 0.118 1.14 0.48 2.73 0.155 0.451 0.732 0.1356 1.17 0.482 2.82 0.171 0.439 0.697 0.1568 1.19 0.502 2.8 PRS_PLINK_0.001 TRUE 585 Renal failure Both 951 14129 11 genitourinary black 14129, 951 3533, 236 3532, 242 3532, 220 3532, 253 -0.0537 0.0517 0.299 0.524 0.948 0.856 1.05 0.0249 0.0942 0.792 0.1015 1.03 0.852 1.23 -0.0717 0.0964 0.457 0.34 0.931 0.771 1.12 0.061 0.0934 0.514 0.2891 1.06 0.885 1.28 PRS_PLINK_0.001 FALSE 585.1 Acute renal failure Both 567 9216 11 genitourinary black 9216, 567 2304, 144 2304, 146 2304, 133 2304, 144 -0.0692 0.0805 0.39 0.4089 0.933 0.797 1.09 0.0128 0.12 0.915 0.03839 1.01 0.8 1.28 -0.0838 0.123 0.496 0.3044 0.92 0.722 1.17 0.000263 0.121 0.998 0.000753 1 0.789 1.27 PRS_PLINK_0.001 FALSE 585.2 Renal failure NOS Both 215 2968 11 genitourinary black 2968, 215 742, 49 742, 57 742, 50 742, 59 -0.00117 0.0593 0.984 0.006912 0.999 0.889 1.12 0.16 0.199 0.422 0.3746 1.17 0.794 1.73 0.0269 0.205 0.896 0.04791 1.03 0.688 1.53 0.173 0.198 0.383 0.4169 1.19 0.806 1.75 PRS_PLINK_0.001 FALSE 585.3 Chronic renal failure [CKD] Both 381 5346 11 genitourinary black 5346, 381 1337, 91 1336, 92 1336, 95 1337, 103 -0.0169 0.0593 0.776 0.1102 0.983 0.875 1.1 0.0143 0.152 0.925 0.03393 1.01 0.753 1.37 0.0369 0.151 0.806 0.09348 1.04 0.772 1.39 0.108 0.148 0.468 0.3301 1.11 0.833 1.49 PRS_PLINK_0.001 FALSE 585.31 Renal dialysis Both 82 1002 11 genitourinary black 1002, 82 251, 21 250, 17 250, 19 251, 25 0.0319 0.0994 0.748 0.1261 1.03 0.85 1.25 -0.212 0.326 0.514 0.2887 0.809 0.427 1.53 -0.128 0.32 0.69 0.1611 0.88 0.47 1.65 0.16 0.302 0.597 0.2243 1.17 0.649 2.12 PRS_PLINK_0.001 FALSE 586 Other disorders of the kidney and ureters Both 554 7129 11 genitourinary black 7129, 554 1782, 137 1782, 128 1782, 152 1782, 137 -0.0598 0.0666 0.369 0.4327 0.942 0.827 1.07 -0.0633 0.127 0.617 0.2094 0.939 0.732 1.2 0.105 0.122 0.389 0.4099 1.11 0.875 1.41 -0.00448 0.125 0.971 0.01263 0.996 0.78 1.27 PRS_PLINK_0.001 FALSE 586.1 Anatomical abnormatilies of kidney and ureters Both 29 447 11 genitourinary black 447, 29 112, 10 112, 4 111, 7 112, 8 0.0871 0.122 0.475 0.3234 1.09 0.859 1.39 -0.839 0.552 0.128 0.8913 0.432 0.147 1.27 -0.237 0.483 0.623 0.2056 0.789 0.306 2.03 -0.201 0.469 0.668 0.1752 0.818 0.326 2.05 PRS_PLINK_0.001 TRUE 586.11 Small kidney Both 24 373 11 genitourinary black 373, 24 94, 6 93, 4 93, 7 93, 7 0.0864 0.119 0.467 0.331 1.09 0.864 1.38 -0.245 0.585 0.675 0.1705 0.783 0.249 2.46 0.194 0.53 0.714 0.146 1.21 0.429 3.43 0.167 0.544 0.76 0.1194 1.18 0.406 3.43 PRS_PLINK_0.001 TRUE 586.2 Cyst of kidney, acquired Both 193 2669 11 genitourinary black 2669, 193 667, 51 667, 46 667, 44 667, 52 -0.0138 0.0713 0.847 0.07226 0.986 0.858 1.13 -0.0999 0.207 0.63 0.2008 0.905 0.603 1.36 -0.15 0.21 0.474 0.3244 0.86 0.57 1.3 0.0168 0.202 0.934 0.0297 1.02 0.684 1.51 PRS_PLINK_0.001 FALSE 586.3 Vascular disorders of kidney/hypertrophy Both 9 153 11 genitourinary black 153, 9 39, 2 38, 2 38, 3 38, 2 0.359 1.32 0.785 0.105 1.43 0.108 18.9 0.26 0.848 0.759 0.1199 1.3 0.246 6.84 0.613 0.874 0.483 0.3162 1.85 0.333 10.2 0.532 0.899 0.554 0.2562 1.7 0.292 9.92 PRS_PLINK_0.001 TRUE 586.4 Stricture/obstruction of ureter Both 167 1971 11 genitourinary black 1971, 167 493, 34 493, 39 492, 48 493, 46 0.0707 0.0805 0.38 0.4206 1.07 0.917 1.26 0.146 0.239 0.54 0.2676 1.16 0.725 1.85 0.325 0.229 0.156 0.806 1.38 0.883 2.17 0.283 0.231 0.22 0.6582 1.33 0.844 2.09 PRS_PLINK_0.001 FALSE 587 Kidney replaced by transpant Both 72 773 11 genitourinary black 773, 72 194, 22 193, 15 193, 18 193, 17 -0.00448 0.0921 0.961 0.01719 0.996 0.831 1.19 -0.34 0.341 0.319 0.4957 0.712 0.364 1.39 -0.206 0.325 0.526 0.2789 0.814 0.431 1.54 -0.201 0.33 0.542 0.2662 0.818 0.428 1.56 PRS_PLINK_0.001 FALSE 588 Disorders resulting from impaired renal function Both 14 213 11 genitourinary black 213, 14 54, 5 53, 0 53, 7 53, 2 0.0243 0.0941 0.796 0.09916 1.02 0.852 1.23 -3.48 1.4 0.0127 1.897 0.0307 0.00198 0.475 -0.0328 0.612 0.957 0.01896 0.968 0.292 3.21 -1.11 0.785 0.159 0.798 0.331 0.0711 1.54 PRS_PLINK_0.001 TRUE 589 Abnormal results of function study of kidney Both 25 233 11 genitourinary black 233, 25 59, 7 58, 11 58, 4 58, 3 -1.08 0.743 0.148 0.8298 0.341 0.0795 1.46 0.199 0.528 0.706 0.1513 1.22 0.434 3.44 -0.684 0.655 0.296 0.5283 0.505 0.14 1.82 -0.946 0.653 0.147 0.8322 0.388 0.108 1.4 PRS_PLINK_0.001 TRUE 590 Pyelonephritis Both 201 2814 11 genitourinary black 2814, 201 704, 54 703, 54 703, 52 704, 41 -0.374 0.244 0.125 0.9019 0.688 0.426 1.11 0.00162 0.197 0.993 0.002862 1 0.68 1.47 -0.0485 0.2 0.808 0.09253 0.953 0.644 1.41 -0.275 0.211 0.192 0.7171 0.76 0.503 1.15 PRS_PLINK_0.001 FALSE 591 Urinary tract infection Both 1973 25993 11 genitourinary black 25993, 1973 6498, 485 6498, 471 6498, 506 6498, 511 -0.0176 0.0269 0.514 0.2891 0.983 0.932 1.04 -0.0291 0.0669 0.664 0.178 0.971 0.852 1.11 0.0429 0.0658 0.515 0.2886 1.04 0.917 1.19 0.0521 0.0657 0.428 0.3683 1.05 0.926 1.2 PRS_PLINK_0.001 FALSE 592 Cystitis and urethritis Both 514 6276 11 genitourinary black 6276, 514 1569, 129 1569, 123 1569, 122 1569, 140 -0.00498 0.0408 0.903 0.04434 0.995 0.919 1.08 -0.0449 0.13 0.73 0.1364 0.956 0.741 1.23 -0.0644 0.131 0.622 0.2059 0.938 0.725 1.21 0.0726 0.127 0.567 0.2465 1.08 0.839 1.38 PRS_PLINK_0.001 FALSE 592.1 Cystitis Both 495 6134 11 genitourinary black 6134, 495 1534, 124 1533, 118 1533, 115 1534, 138 0.00442 0.0422 0.916 0.03791 1 0.925 1.09 -0.0486 0.133 0.714 0.1461 0.953 0.734 1.24 -0.0767 0.134 0.567 0.2464 0.926 0.712 1.2 0.0969 0.128 0.451 0.3461 1.1 0.857 1.42 PRS_PLINK_0.001 FALSE 592.11 Acute cystitis Both 19 285 11 genitourinary black 285, 19 72, 6 71, 2 71, 8 71, 3 -0.503 0.837 0.548 0.261 0.605 0.117 3.12 -0.898 0.715 0.209 0.6801 0.407 0.1 1.65 0.221 0.532 0.678 0.1689 1.25 0.439 3.54 -0.62 0.653 0.342 0.4657 0.538 0.15 1.93 PRS_PLINK_0.001 TRUE 592.12 Chronic cystitis Both 148 1879 11 genitourinary black 1879, 148 470, 31 470, 38 469, 37 470, 42 0.0766 0.0523 0.143 0.8442 1.08 0.974 1.2 0.216 0.246 0.381 0.4191 1.24 0.766 2.01 0.162 0.248 0.513 0.29 1.18 0.724 1.91 0.314 0.243 0.196 0.7077 1.37 0.851 2.2 PRS_PLINK_0.001 FALSE 592.13 Chronic interstitial cystitis Both 53 467 11 genitourinary black 467, 53 117, 13 117, 17 116, 12 117, 11 0.0134 0.101 0.894 0.04858 1.01 0.832 1.24 0.181 0.38 0.633 0.1984 1.2 0.569 2.53 -0.154 0.406 0.704 0.1522 0.857 0.387 1.9 -0.293 0.42 0.484 0.3148 0.746 0.328 1.7 PRS_PLINK_0.001 FALSE 592.2 Urethritis and urethral syndrome Both 34 402 11 genitourinary black 402, 34 101, 8 100, 9 100, 10 101, 7 0.0229 0.0736 0.756 0.1217 1.02 0.886 1.18 0.211 0.48 0.66 0.1803 1.23 0.482 3.16 0.208 0.476 0.663 0.1788 1.23 0.484 3.13 0.157 0.524 0.764 0.1168 1.17 0.419 3.27 PRS_PLINK_0.001 TRUE 593 Hematuria Both 2909 34170 11 genitourinary black 34170, 2909 8543, 729 8542, 740 8542, 709 8543, 731 -0.0197 0.0205 0.338 0.4716 0.981 0.942 1.02 0.0148 0.0544 0.786 0.1047 1.01 0.912 1.13 -0.0262 0.0549 0.633 0.1987 0.974 0.875 1.08 0.00344 0.0545 0.95 0.02242 1 0.902 1.12 PRS_PLINK_0.001 FALSE 594 Urinary calculus Both 1186 13710 11 genitourinary black 13710, 1186 3428, 302 3427, 298 3427, 301 3428, 285 -0.0758 0.0559 0.175 0.7565 0.927 0.831 1.03 -0.0124 0.085 0.884 0.05346 0.988 0.836 1.17 -0.00609 0.0848 0.943 0.02561 0.994 0.842 1.17 -0.061 0.0859 0.478 0.3209 0.941 0.795 1.11 PRS_PLINK_0.001 FALSE 594.1 Calculus of kidney Both 596 6827 11 genitourinary black 6827, 596 1707, 157 1707, 157 1706, 144 1707, 138 -0.0363 0.0483 0.453 0.3441 0.964 0.877 1.06 -0.00409 0.118 0.972 0.01222 0.996 0.791 1.25 -0.0916 0.12 0.446 0.3507 0.912 0.721 1.15 -0.14 0.121 0.248 0.6047 0.87 0.686 1.1 PRS_PLINK_0.001 FALSE 594.2 Calculus of lower urinary tract Both 132 1631 11 genitourinary black 1631, 132 408, 30 408, 31 407, 39 408, 32 0.0764 0.105 0.465 0.3323 1.08 0.879 1.33 0.036 0.261 0.89 0.05042 1.04 0.621 1.73 0.283 0.25 0.258 0.5876 1.33 0.812 2.17 0.109 0.26 0.673 0.1718 1.12 0.671 1.86 PRS_PLINK_0.001 FALSE 594.3 Calculus of ureter Both 422 5248 11 genitourinary black 5248, 422 1312, 104 1312, 107 1312, 106 1312, 105 -0.034 0.0671 0.612 0.213 0.967 0.847 1.1 0.0246 0.143 0.863 0.06387 1.02 0.775 1.36 0.0144 0.143 0.919 0.03648 1.01 0.767 1.34 0.011 0.143 0.938 0.02758 1.01 0.764 1.34 PRS_PLINK_0.001 FALSE 594.8 Renal colic Both 378 4418 11 genitourinary black 4418, 378 1105, 88 1104, 82 1104, 98 1105, 110 0.000502 0.0498 0.992 0.003507 1 0.907 1.1 -0.0598 0.158 0.705 0.1518 0.942 0.691 1.28 0.0993 0.152 0.513 0.2899 1.1 0.82 1.49 0.221 0.148 0.137 0.8639 1.25 0.932 1.67 PRS_PLINK_0.001 FALSE 595 Hydronephrosis Both 350 4156 11 genitourinary black 4156, 350 1039, 89 1039, 72 1039, 101 1039, 88 -0.00877 0.0708 0.901 0.0451 0.991 0.863 1.14 -0.201 0.163 0.219 0.6602 0.818 0.594 1.13 0.123 0.151 0.416 0.3811 1.13 0.841 1.52 0.00835 0.156 0.957 0.01898 1.01 0.743 1.37 PRS_PLINK_0.001 FALSE 596 Other disorders of bladder Both 1784 20687 11 genitourinary black 20687, 1784 5172, 425 5172, 422 5171, 436 5172, 501 0.0213 0.0192 0.266 0.575 1.02 0.984 1.06 -0.00592 0.0714 0.934 0.02969 0.994 0.864 1.14 0.0253 0.0708 0.721 0.1424 1.03 0.893 1.18 0.167 0.0688 0.0151 1.821 1.18 1.03 1.35 PRS_PLINK_0.001 FALSE 596.1 Bladder neck obstruction Both 391 4117 11 genitourinary black 4117, 391 1030, 78 1029, 110 1029, 87 1029, 116 0.0348 0.0413 0.4 0.398 1.04 0.955 1.12 0.338 0.153 0.0278 1.557 1.4 1.04 1.89 0.104 0.161 0.516 0.2876 1.11 0.81 1.52 0.401 0.152 0.00835 2.078 1.49 1.11 2.01 PRS_PLINK_0.001 FALSE 596.5 Functional disorders of bladder Both 243 3621 11 genitourinary black 3621, 243 906, 60 905, 66 905, 58 905, 59 -0.0464 0.0813 0.568 0.2456 0.955 0.814 1.12 0.12 0.183 0.51 0.2923 1.13 0.788 1.61 -0.0368 0.188 0.845 0.0733 0.964 0.667 1.39 -0.0132 0.187 0.944 0.02502 0.987 0.684 1.42 PRS_PLINK_0.001 FALSE 597 Other disorders of urethra and urinary tract Both 716 8256 11 genitourinary black 8256, 716 2064, 202 2064, 181 2064, 158 2064, 175 0.00245 0.0371 0.947 0.02351 1 0.932 1.08 -0.114 0.107 0.284 0.5473 0.892 0.723 1.1 -0.252 0.11 0.0225 1.648 0.777 0.626 0.965 -0.137 0.108 0.204 0.6908 0.872 0.706 1.08 PRS_PLINK_0.001 FALSE 597.1 Urethral stricture (not specified as infectious) Both 604 7030 11 genitourinary black 7030, 604 1758, 164 1757, 156 1757, 129 1758, 155 0.0176 0.0354 0.62 0.2074 1.02 0.949 1.09 -0.0555 0.116 0.633 0.1984 0.946 0.753 1.19 -0.247 0.122 0.0429 1.367 0.781 0.615 0.992 -0.0564 0.117 0.629 0.2014 0.945 0.752 1.19 PRS_PLINK_0.001 FALSE 597.2 Urinary complications NEC Both 7 189 11 genitourinary black 189, 7 48, 0 47, 4 47, 1 47, 2 0.676 1.06 0.523 0.2813 1.97 0.247 15.6 1.96 1.17 0.0929 1.032 7.11 0.721 70.1 0.755 1.23 0.54 0.2678 2.13 0.19 23.8 1.36 1.15 0.237 0.626 3.88 0.411 36.7 PRS_PLINK_0.001 TRUE 598 Abnormal findings on examination of urine Both 676 7247 11 genitourinary black 7247, 676 1812, 165 1812, 186 1811, 156 1812, 169 0.0293 0.0309 0.342 0.4659 1.03 0.969 1.09 0.118 0.112 0.29 0.5382 1.13 0.904 1.4 -0.0604 0.116 0.603 0.2196 0.941 0.75 1.18 0.028 0.114 0.806 0.09354 1.03 0.822 1.29 PRS_PLINK_0.001 FALSE 598.9 Other nonspecific findings on examination of urine Both 47 612 11 genitourinary black 612, 47 153, 11 153, 11 153, 12 153, 13 0.0247 0.081 0.76 0.119 1.03 0.875 1.2 0.0682 0.421 0.871 0.05986 1.07 0.469 2.44 0.158 0.414 0.702 0.1534 1.17 0.52 2.64 0.172 0.411 0.674 0.171 1.19 0.531 2.66 PRS_PLINK_0.001 TRUE 599 Other symptoms/disorders or the urinary system Both 3269 39247 11 genitourinary black 39247, 3269 9811, 759 9812, 864 9811, 810 9812, 836 0.00655 0.0169 0.698 0.1559 1.01 0.974 1.04 0.13 0.0517 0.0117 1.933 1.14 1.03 1.26 0.0653 0.0525 0.213 0.6706 1.07 0.963 1.18 0.0956 0.0521 0.0664 1.178 1.1 0.994 1.22 PRS_PLINK_0.001 FALSE 599.1 Urinary obstruction Both 30 343 11 genitourinary black 343, 30 86, 10 86, 8 85, 5 86, 7 -0.178 0.583 0.761 0.1188 0.837 0.267 2.63 -0.32 0.498 0.52 0.2839 0.726 0.274 1.93 -0.7 0.53 0.186 0.7299 0.496 0.176 1.4 -0.339 0.49 0.489 0.3109 0.713 0.273 1.86 PRS_PLINK_0.001 TRUE 599.2 Retention of urine Both 1217 14274 11 genitourinary black 14274, 1217 3569, 299 3568, 317 3568, 274 3569, 327 0.0335 0.0232 0.148 0.8295 1.03 0.988 1.08 0.0513 0.0839 0.541 0.267 1.05 0.893 1.24 -0.0891 0.0868 0.304 0.5167 0.915 0.772 1.08 0.0868 0.0833 0.297 0.5267 1.09 0.926 1.28 PRS_PLINK_0.001 FALSE 599.3 Dysuria Both 201 2590 11 genitourinary black 2590, 201 648, 54 647, 65 647, 36 648, 46 -0.391 0.239 0.101 0.9935 0.676 0.423 1.08 0.192 0.19 0.313 0.5044 1.21 0.834 1.76 -0.416 0.219 0.0579 1.237 0.66 0.429 1.01 -0.147 0.205 0.473 0.3254 0.863 0.577 1.29 PRS_PLINK_0.001 FALSE 599.4 Urinary incontinence Both 1451 18665 11 genitourinary black 18665, 1451 4666, 332 4666, 380 4666, 378 4666, 361 -0.0202 0.0298 0.499 0.302 0.98 0.924 1.04 0.135 0.0778 0.082 1.086 1.14 0.983 1.33 0.128 0.0778 0.101 0.9973 1.14 0.976 1.32 0.0839 0.0787 0.286 0.543 1.09 0.932 1.27 PRS_PLINK_0.001 FALSE 599.5 Frequency of urination and polyuria Both 752 8667 11 genitourinary black 8667, 752 2167, 171 2167, 205 2166, 189 2167, 187 -0.0507 0.0568 0.372 0.4296 0.951 0.85 1.06 0.189 0.108 0.0795 1.1 1.21 0.978 1.49 0.101 0.109 0.358 0.4457 1.11 0.892 1.37 0.0946 0.11 0.389 0.4103 1.1 0.886 1.36 PRS_PLINK_0.001 FALSE 599.6 Oliguria and anuria Both 21 230 11 genitourinary black 230, 21 58, 2 57, 8 57, 6 58, 5 -0.43 0.749 0.566 0.2471 0.651 0.15 2.83 0.924 0.699 0.186 0.7308 2.52 0.641 9.91 0.545 0.757 0.471 0.3266 1.72 0.391 7.6 0.689 0.721 0.339 0.4695 1.99 0.485 8.18 PRS_PLINK_0.001 TRUE 599.8 Other symptoms involving urinary system Both 10 125 11 genitourinary black 125, 10 32, 2 31, 2 31, 2 31, 4 -0.0167 0.877 0.985 0.006668 0.983 0.176 5.48 0.48 1.01 0.634 0.198 1.62 0.224 11.6 -0.395 0.966 0.683 0.1658 0.674 0.101 4.48 PRS_PLINK_0.001 TRUE 599.9 Other abnormality of urination Both 340 4066 11 genitourinary black 4066, 340 1017, 82 1016, 74 1016, 85 1017, 99 0.0448 0.0356 0.208 0.6815 1.05 0.975 1.12 -0.101 0.165 0.54 0.2677 0.904 0.654 1.25 0.0406 0.16 0.8 0.09669 1.04 0.76 1.43 0.199 0.155 0.199 0.7006 1.22 0.9 1.65 PRS_PLINK_0.001 FALSE 600 Hyperplasia of prostate Male 2209 19061 11 genitourinary black 19061, 2209 4766, 563 4765, 563 4765, 492 4765, 591 -0.00325 0.0219 0.882 0.05449 0.997 0.955 1.04 5.56e-05 0.0631 0.999 0.0003054 1 0.884 1.13 -0.138 0.0652 0.0336 1.474 0.871 0.766 0.989 0.0569 0.0625 0.363 0.44 1.06 0.936 1.2 PRS_PLINK_0.001 FALSE 601 Inflammatory diseases of prostate Male 396 4509 11 genitourinary black 4509, 396 1128, 107 1127, 97 1127, 92 1127, 100 0.0418 0.0334 0.21 0.6771 1.04 0.977 1.11 -0.0899 0.146 0.537 0.27 0.914 0.687 1.22 -0.146 0.147 0.322 0.492 0.864 0.647 1.15 -0.059 0.145 0.684 0.1652 0.943 0.71 1.25 PRS_PLINK_0.001 FALSE 601.1 Prostatitis Male 304 3417 11 genitourinary black 3417, 304 855, 87 854, 77 854, 66 854, 74 -0.332 0.201 0.0974 1.011 0.717 0.484 1.06 -0.13 0.163 0.425 0.3714 0.878 0.638 1.21 -0.275 0.169 0.103 0.986 0.759 0.545 1.06 -0.145 0.164 0.378 0.4227 0.865 0.627 1.19 PRS_PLINK_0.001 FALSE 601.11 Acute prostatitis Male 48 539 11 genitourinary black 539, 48 135, 18 135, 13 134, 7 135, 10 -0.882 0.497 0.0755 1.122 0.414 0.156 1.09 -0.3 0.377 0.426 0.371 0.741 0.354 1.55 -0.895 0.441 0.0424 1.373 0.409 0.172 0.97 -0.568 0.399 0.154 0.813 0.566 0.259 1.24 PRS_PLINK_0.001 TRUE 601.12 Chronic prostatitis Male 178 1958 11 genitourinary black 1958, 178 490, 51 489, 45 489, 33 490, 49 -0.0334 0.117 0.775 0.1109 0.967 0.77 1.22 -0.126 0.212 0.554 0.2567 0.882 0.582 1.34 -0.453 0.229 0.0483 1.316 0.636 0.406 0.997 -0.0395 0.209 0.85 0.07062 0.961 0.638 1.45 PRS_PLINK_0.001 FALSE 601.3 Orchitis and epididymitis Male 10 120 11 genitourinary black 120, 10 30, 4 30, 1 30, 1 30, 4 0.551 1.06 0.605 0.2184 1.73 0.215 14 -0.901 0.929 0.332 0.4783 0.406 0.0657 2.51 -2.5 1.3 0.0544 1.265 0.0819 0.00639 1.05 0.0234 0.73 0.974 0.01125 1.02 0.245 4.28 PRS_PLINK_0.001 TRUE 601.4 Balanoposthitis Male 59 590 11 genitourinary black 590, 59 148, 16 147, 15 147, 15 148, 13 -0.0221 0.0892 0.804 0.09459 0.978 0.821 1.16 -0.107 0.367 0.772 0.1126 0.899 0.438 1.85 -0.148 0.374 0.693 0.1593 0.863 0.414 1.8 -0.152 0.38 0.69 0.1614 0.859 0.408 1.81 PRS_PLINK_0.001 FALSE 601.8 Other inflammatory disorders of male genital organs Male 50 595 11 genitourinary black 595, 50 149, 10 149, 9 148, 14 149, 17 0.106 0.0432 0.014 1.855 1.11 1.02 1.21 -0.117 0.443 0.792 0.1013 0.89 0.373 2.12 0.348 0.411 0.397 0.4015 1.42 0.633 3.17 0.491 0.397 0.215 0.6666 1.63 0.751 3.56 PRS_PLINK_0.001 TRUE 602 Other disorders of prostate Male 292 2827 11 genitourinary black 2827, 292 707, 80 707, 70 706, 59 707, 83 -0.025 0.0943 0.791 0.1017 0.975 0.811 1.17 -0.136 0.171 0.427 0.3695 0.873 0.624 1.22 -0.304 0.178 0.0882 1.055 0.738 0.52 1.05 0.0326 0.165 0.843 0.07409 1.03 0.748 1.43 PRS_PLINK_0.001 FALSE 603 Other disorders of testis Male 385 4631 11 genitourinary black 4631, 385 1158, 97 1158, 109 1157, 95 1158, 84 -0.118 0.129 0.357 0.4471 0.888 0.69 1.14 0.11 0.145 0.447 0.3499 1.12 0.841 1.48 -0.0293 0.15 0.845 0.07312 0.971 0.724 1.3 -0.152 0.154 0.324 0.4891 0.859 0.635 1.16 PRS_PLINK_0.001 FALSE 603.1 Hydrocele Male 254 2880 11 genitourinary black 2880, 254 720, 68 720, 69 720, 61 720, 56 -0.295 0.217 0.175 0.7566 0.745 0.486 1.14 0.0114 0.177 0.949 0.02277 1.01 0.714 1.43 -0.109 0.183 0.552 0.2582 0.897 0.627 1.28 -0.197 0.187 0.291 0.5356 0.821 0.569 1.18 PRS_PLINK_0.001 FALSE 604 Disorders of penis Male 617 7093 11 genitourinary black 7093, 617 1774, 156 1773, 149 1773, 144 1773, 168 0.0573 0.0357 0.109 0.9637 1.06 0.987 1.14 -0.0577 0.119 0.628 0.2023 0.944 0.747 1.19 -0.0864 0.12 0.471 0.3265 0.917 0.725 1.16 0.0705 0.116 0.543 0.2653 1.07 0.855 1.35 PRS_PLINK_0.001 FALSE 604.1 Redundant prepuce and phimosis/BXO Male 515 5900 11 genitourinary black 5900, 515 1475, 125 1475, 124 1475, 122 1475, 144 0.0702 0.0367 0.0558 1.254 1.07 0.998 1.15 -0.0175 0.132 0.894 0.04851 0.983 0.759 1.27 -0.0342 0.132 0.795 0.09943 0.966 0.746 1.25 0.133 0.127 0.295 0.53 1.14 0.89 1.47 PRS_PLINK_0.001 FALSE 605 Erectile dysfunction [ED] Male 43 569 11 genitourinary black 569, 43 143, 14 142, 11 142, 10 142, 8 -0.714 0.525 0.174 0.7597 0.489 0.175 1.37 -0.272 0.411 0.509 0.2932 0.762 0.34 1.71 -0.333 0.417 0.424 0.3726 0.717 0.317 1.62 -0.512 0.443 0.248 0.6056 0.6 0.252 1.43 PRS_PLINK_0.001 TRUE 608 Other disorders of male genital organs Male 500 6084 11 genitourinary black 6084, 500 1521, 135 1521, 125 1521, 124 1521, 116 0.0375 0.0275 0.174 0.7603 1.04 0.984 1.1 -0.082 0.129 0.524 0.2804 0.921 0.716 1.19 -0.0839 0.129 0.516 0.2873 0.92 0.714 1.18 -0.15 0.131 0.252 0.5986 0.86 0.665 1.11 PRS_PLINK_0.001 FALSE 609 Male infertility and abnormal spermatozoa Male 48 456 11 genitourinary black 456, 48 114, 11 114, 14 114, 12 114, 11 -0.428 0.529 0.418 0.3784 0.652 0.231 1.84 0.167 0.413 0.686 0.1637 1.18 0.526 2.66 0.0573 0.422 0.892 0.04963 1.06 0.463 2.42 0.0206 0.429 0.962 0.01699 1.02 0.44 2.37 PRS_PLINK_0.001 TRUE 609.1 Infertility, male Male 12 145 11 genitourinary black 145, 12 37, 7 36, 4 36, 1 36, 0 -3.14 1.18 0.0081 2.091 0.0434 0.00426 0.443 -0.431 0.634 0.497 0.304 0.65 0.187 2.25 -1.38 0.842 0.102 0.9902 0.253 0.0486 1.32 -2.44 1.25 0.0518 1.286 0.0873 0.00749 1.02 PRS_PLINK_0.001 TRUE 609.2 Abnormal spermatozoa Male 37 360 11 genitourinary black 360, 37 90, 6 90, 9 90, 11 90, 11 0.047 0.132 0.721 0.1418 1.05 0.81 1.36 0.397 0.533 0.456 0.3408 1.49 0.524 4.22 0.643 0.5 0.199 0.7018 1.9 0.713 5.07 0.508 0.512 0.321 0.4938 1.66 0.61 4.53 PRS_PLINK_0.001 TRUE 610 Benign mammary dysplasias Female 499 5416 11 genitourinary black 5416, 499 1354, 120 1354, 125 1354, 143 1354, 111 -9.45e-05 0.0472 0.998 0.0006941 1 0.912 1.1 0.0407 0.133 0.759 0.1197 1.04 0.803 1.35 0.168 0.129 0.192 0.7161 1.18 0.919 1.52 -0.0809 0.136 0.553 0.2572 0.922 0.706 1.21 PRS_PLINK_0.001 FALSE 610.1 Cystic mastopathy Female 166 1954 11 genitourinary black 1954, 166 489, 35 488, 53 488, 38 489, 40 0.00223 0.0813 0.978 0.009593 1 0.855 1.18 0.409 0.224 0.0685 1.164 1.5 0.969 2.34 0.0886 0.239 0.71 0.1487 1.09 0.685 1.74 0.123 0.237 0.605 0.2182 1.13 0.711 1.8 PRS_PLINK_0.001 FALSE 610.2 Fibroadenosis of breast Female 62 674 11 genitourinary black 674, 62 169, 19 168, 11 168, 22 169, 10 0.0113 0.107 0.916 0.03818 1.01 0.82 1.25 -0.522 0.38 0.169 0.7714 0.593 0.282 1.25 0.125 0.327 0.702 0.154 1.13 0.598 2.15 -0.562 0.391 0.15 0.8233 0.57 0.265 1.23 PRS_PLINK_0.001 FALSE 610.3 Fibrosclerosis of breast Female 62 613 11 genitourinary black 613, 62 154, 15 153, 16 153, 18 153, 13 0.0457 0.126 0.716 0.1451 1.05 0.818 1.34 0.0309 0.363 0.932 0.03054 1.03 0.506 2.1 0.045 0.364 0.902 0.04495 1.05 0.512 2.14 -0.223 0.385 0.562 0.2502 0.8 0.377 1.7 PRS_PLINK_0.001 FALSE 610.4 Benign neoplasm of breast Female 295 3012 11 genitourinary black 3012, 295 753, 75 753, 68 753, 84 753, 68 0.0279 0.05 0.577 0.2388 1.03 0.932 1.13 -0.0925 0.174 0.594 0.226 0.912 0.649 1.28 0.0984 0.166 0.554 0.2568 1.1 0.797 1.53 -0.116 0.174 0.505 0.2967 0.89 0.633 1.25 PRS_PLINK_0.001 FALSE 610.8 Other specified benign mammary dysplasias Female 127 1424 11 genitourinary black 1424, 127 356, 29 356, 29 356, 38 356, 31 0.0246 0.088 0.779 0.1083 1.02 0.863 1.22 -0.0101 0.269 0.97 0.01324 0.99 0.584 1.68 0.246 0.254 0.333 0.4781 1.28 0.777 2.1 0.056 0.263 0.832 0.08003 1.06 0.631 1.77 PRS_PLINK_0.001 FALSE 611 Abnormal findings on mammogram or breast exam Both 329 3516 11 genitourinary black 3516, 329 879, 90 879, 77 879, 87 879, 75 0.0278 0.0369 0.452 0.3453 1.03 0.956 1.11 -0.168 0.162 0.299 0.5238 0.846 0.616 1.16 -0.0239 0.157 0.879 0.05606 0.976 0.718 1.33 -0.179 0.162 0.27 0.5693 0.836 0.608 1.15 PRS_PLINK_0.001 FALSE 611.1 Abnormal mammogram Both 9 117 11 genitourinary black 117, 9 30, 4 29, 2 29, 3 29, 0 -3.06 1.35 0.0239 1.622 0.0469 0.0033 0.667 -0.663 0.858 0.44 0.357 0.515 0.0958 2.77 PRS_PLINK_0.001 TRUE 611.3 Lump or mass in breast Both 321 3405 11 genitourinary black 3405, 321 852, 86 851, 73 851, 87 851, 75 0.0257 0.0364 0.48 0.3184 1.03 0.955 1.1 -0.178 0.166 0.283 0.5489 0.837 0.605 1.16 0.0161 0.159 0.919 0.03651 1.02 0.745 1.39 -0.134 0.164 0.413 0.3837 0.874 0.634 1.21 PRS_PLINK_0.001 FALSE 612 Breast conditions, congenital or relating to hormones Both 159 1990 11 genitourinary black 1990, 159 498, 34 497, 38 497, 45 498, 42 0.0372 0.0598 0.534 0.2725 1.04 0.923 1.17 0.0968 0.24 0.687 0.163 1.1 0.688 1.76 0.261 0.232 0.262 0.5815 1.3 0.823 2.05 0.241 0.237 0.308 0.5109 1.27 0.8 2.02 PRS_PLINK_0.001 FALSE 612.2 Hypertrophy of breast (Gynecomastia) Both 145 1888 11 genitourinary black 1888, 145 472, 28 472, 36 472, 43 472, 38 0.0348 0.0581 0.549 0.2606 1.04 0.924 1.16 0.235 0.255 0.355 0.4497 1.27 0.768 2.08 0.412 0.248 0.0964 1.016 1.51 0.929 2.45 0.346 0.255 0.175 0.7582 1.41 0.858 2.33 PRS_PLINK_0.001 FALSE 612.3 Congenital anomalies of breast Both 17 174 11 genitourinary black 174, 17 44, 6 43, 2 43, 3 44, 6 0.165 0.142 0.247 0.6077 1.18 0.892 1.56 -0.793 0.772 0.304 0.5165 0.452 0.0995 2.06 -1.04 0.732 0.154 0.8134 0.352 0.0839 1.48 0.0173 0.616 0.978 0.009821 1.02 0.304 3.4 PRS_PLINK_0.001 TRUE 613 Other nonmalignant breast conditions Both 294 3511 11 genitourinary black 3511, 294 878, 68 878, 74 877, 88 878, 64 -0.0395 0.0893 0.658 0.1815 0.961 0.807 1.15 0.0656 0.173 0.705 0.1517 1.07 0.76 1.5 0.243 0.167 0.146 0.8347 1.28 0.919 1.77 -0.0648 0.178 0.717 0.1447 0.937 0.661 1.33 PRS_PLINK_0.001 FALSE 613.1 Inflammatory disease of breast Both 118 1522 11 genitourinary black 1522, 118 381, 23 380, 25 380, 43 381, 27 0.0755 0.11 0.493 0.307 1.08 0.869 1.34 0.0699 0.292 0.811 0.09112 1.07 0.605 1.9 0.623 0.264 0.0185 1.733 1.86 1.11 3.13 0.163 0.288 0.571 0.2433 1.18 0.669 2.07 PRS_PLINK_0.001 FALSE 613.5 Mastodynia Both 12 159 11 genitourinary black 159, 12 40, 2 40, 5 39, 3 40, 2 -0.469 0.892 0.599 0.2224 0.626 0.109 3.59 0.492 0.793 0.535 0.2716 1.64 0.346 7.74 -0.119 0.791 0.881 0.05517 0.888 0.188 4.19 PRS_PLINK_0.001 TRUE 613.7 Other signs and symptoms in breast Both 111 1363 11 genitourinary black 1363, 111 341, 23 341, 33 340, 27 341, 28 0.0149 0.0663 0.822 0.08513 1.02 0.891 1.16 0.385 0.279 0.168 0.7753 1.47 0.85 2.54 0.257 0.289 0.374 0.4268 1.29 0.734 2.28 PRS_PLINK_0.001 FALSE 613.8 Other specified disorders of breast Both 64 681 11 genitourinary black 681, 64 171, 17 170, 18 170, 21 170, 8 -0.639 0.428 0.135 0.8696 0.528 0.228 1.22 0.245 0.334 0.463 0.334 1.28 0.663 2.46 -0.612 0.425 0.15 0.8241 0.542 0.236 1.25 PRS_PLINK_0.001 FALSE 613.9 Breast disorder NOS Both 36 441 11 genitourinary black 441, 36 111, 11 110, 8 110, 8 110, 9 0.0403 0.0974 0.679 0.168 1.04 0.86 1.26 -0.259 0.464 0.578 0.2383 0.772 0.311 1.92 PRS_PLINK_0.001 TRUE 614 Inflammatory diseases of female pelvic organs Female 1105 12850 11 genitourinary black 12850, 1105 3213, 269 3212, 273 3212, 285 3213, 278 0.0141 0.0263 0.593 0.2273 1.01 0.963 1.07 0.0168 0.0893 0.851 0.07012 1.02 0.854 1.21 0.0622 0.0884 0.482 0.3169 1.06 0.895 1.27 0.0311 0.0889 0.726 0.139 1.03 0.867 1.23 PRS_PLINK_0.001 FALSE 614.1 Pelvic peritoneal adhesions, female (postoperative) (postinfection) Female 465 5719 11 genitourinary black 5719, 465 1430, 110 1430, 125 1429, 116 1430, 114 0.0277 0.0342 0.417 0.3804 1.03 0.962 1.1 0.134 0.135 0.324 0.4901 1.14 0.877 1.49 0.0665 0.138 0.629 0.2014 1.07 0.816 1.4 0.0428 0.138 0.757 0.121 1.04 0.796 1.37 PRS_PLINK_0.001 FALSE 614.3 Pelvic inflammatory disease (PID) Female 148 1864 11 genitourinary black 1864, 148 466, 40 466, 39 466, 36 466, 33 0.0662 0.0408 0.105 0.9783 1.07 0.986 1.16 -0.0161 0.231 0.944 0.02488 0.984 0.626 1.55 -0.0985 0.235 0.675 0.1706 0.906 0.572 1.44 -0.192 0.24 0.424 0.3729 0.825 0.515 1.32 PRS_PLINK_0.001 FALSE 614.31 Acute inflammatory pelvic disease Female 9 144 11 genitourinary black 144, 9 36, 2 36, 4 36, 2 36, 1 1.04 0.854 0.223 0.6525 2.84 0.531 15.1 -0.00673 0.846 0.994 0.002763 0.993 0.189 5.21 -0.0436 0.979 0.964 0.01572 0.957 0.14 6.52 PRS_PLINK_0.001 TRUE 614.32 Chronic inflammatory pelvic disease Female 73 912 11 genitourinary black 912, 73 228, 20 228, 22 228, 16 228, 15 0.0203 0.0947 0.83 0.08093 1.02 0.848 1.23 0.113 0.314 0.719 0.1434 1.12 0.605 2.07 -0.231 0.341 0.498 0.3026 0.794 0.407 1.55 -0.26 0.345 0.45 0.3465 0.771 0.392 1.51 PRS_PLINK_0.001 FALSE 614.33 Pelvic inflammatory disease, NOS Female 61 777 11 genitourinary black 777, 61 195, 19 194, 11 194, 14 194, 17 0.012 0.0972 0.901 0.04504 1.01 0.837 1.22 -0.574 0.378 0.128 0.8911 0.563 0.269 1.18 -0.319 0.356 0.371 0.4305 0.727 0.362 1.46 -0.176 0.345 0.609 0.2152 0.838 0.426 1.65 PRS_PLINK_0.001 FALSE 614.4 Inflammatory diseases of uterus, except cervix Female 60 614 11 genitourinary black 614, 60 154, 22 153, 12 153, 9 154, 17 0.0311 0.125 0.803 0.09504 1.03 0.808 1.32 -0.639 0.367 0.0818 1.087 0.528 0.257 1.08 -0.819 0.397 0.0389 1.41 0.441 0.203 0.959 -0.247 0.335 0.46 0.3372 0.781 0.405 1.5 PRS_PLINK_0.001 FALSE 614.5 Inflammatory disease of cervix, vagina, and vulva Female 530 5894 11 genitourinary black 5894, 530 1474, 122 1473, 130 1473, 133 1474, 145 0.0175 0.0376 0.642 0.1926 1.02 0.945 1.1 0.0595 0.131 0.649 0.1876 1.06 0.821 1.37 0.0822 0.13 0.527 0.2779 1.09 0.841 1.4 0.169 0.128 0.185 0.7329 1.18 0.922 1.52 PRS_PLINK_0.001 FALSE 614.51 Cervicitis and endocervicitis Female 254 2908 11 genitourinary black 2908, 254 727, 63 727, 62 727, 57 727, 72 0.036 0.0412 0.382 0.4182 1.04 0.956 1.12 -0.0157 0.185 0.933 0.03035 0.984 0.685 1.41 -0.089 0.188 0.637 0.1962 0.915 0.632 1.32 0.137 0.179 0.443 0.3537 1.15 0.808 1.63 PRS_PLINK_0.001 FALSE 614.52 Vaginitis and vulvovaginitis Female 78 962 11 genitourinary black 962, 78 241, 16 240, 20 240, 17 241, 25 0.0486 0.0817 0.552 0.2579 1.05 0.894 1.23 0.23 0.335 0.492 0.3076 1.26 0.653 2.43 0.0152 0.351 0.966 0.01524 1.02 0.511 2.02 0.408 0.324 0.207 0.6841 1.5 0.798 2.84 PRS_PLINK_0.001 FALSE 614.53 Cyst or abscess of Bartholin's gland Female 160 1722 11 genitourinary black 1722, 160 431, 36 430, 35 430, 48 431, 41 0.0108 0.0611 0.86 0.06533 1.01 0.897 1.14 -0.0507 0.243 0.835 0.07844 0.951 0.59 1.53 0.296 0.228 0.193 0.7148 1.34 0.861 2.1 0.151 0.235 0.522 0.2823 1.16 0.733 1.84 PRS_PLINK_0.001 FALSE 614.54 Abscess or ulceration of vulva Female 52 565 11 genitourinary black 565, 52 142, 14 141, 11 141, 18 141, 9 -0.574 0.518 0.267 0.5729 0.563 0.204 1.55 -0.355 0.418 0.396 0.4026 0.701 0.309 1.59 0.139 0.37 0.707 0.1507 1.15 0.556 2.38 -0.376 0.428 0.38 0.4199 0.687 0.297 1.59 PRS_PLINK_0.001 FALSE 615 Endometriosis Female 843 9115 11 genitourinary black 9115, 843 2278, 209 2279, 206 2278, 208 2279, 220 0.0328 0.0266 0.218 0.6624 1.03 0.981 1.09 -0.0153 0.102 0.881 0.05486 0.985 0.806 1.2 -0.00141 0.102 0.989 0.004808 0.999 0.818 1.22 0.051 0.101 0.613 0.2128 1.05 0.864 1.28 PRS_PLINK_0.001 FALSE 617 Disorders secondary to childbirth, surgery, trauma Female 57 648 11 genitourinary black 648, 57 162, 8 162, 17 162, 16 162, 16 0.0422 0.0629 0.503 0.2986 1.04 0.922 1.18 0.717 0.421 0.0881 1.055 2.05 0.899 4.67 0.56 0.421 0.183 0.7373 1.75 0.767 4 0.719 0.429 0.0936 1.029 2.05 0.886 4.76 PRS_PLINK_0.001 FALSE 618 Genital prolapse Female 2183 24331 11 genitourinary black 24331, 2183 6082, 516 6083, 546 6082, 590 6083, 531 -0.018 0.0239 0.452 0.3448 0.982 0.937 1.03 0.0592 0.064 0.355 0.4502 1.06 0.936 1.2 0.134 0.0629 0.0334 1.476 1.14 1.01 1.29 0.0304 0.0644 0.637 0.1957 1.03 0.909 1.17 PRS_PLINK_0.001 FALSE 618.1 Prolapse of vaginal walls Female 1350 15293 11 genitourinary black 15293, 1350 3824, 333 3823, 345 3823, 367 3823, 305 -0.0986 0.0555 0.0756 1.121 0.906 0.813 1.01 0.0373 0.08 0.642 0.1928 1.04 0.887 1.21 0.0976 0.0789 0.216 0.6646 1.1 0.944 1.29 -0.0861 0.0824 0.296 0.5289 0.917 0.781 1.08 PRS_PLINK_0.001 FALSE 618.2 Uterine/Uterovaginal prolapse Female 989 11290 11 genitourinary black 11290, 989 2822, 228 2822, 247 2822, 277 2823, 237 0.013 0.0264 0.623 0.2058 1.01 0.962 1.07 0.0833 0.0954 0.383 0.4172 1.09 0.902 1.31 0.192 0.0931 0.0389 1.41 1.21 1.01 1.45 0.0392 0.0963 0.684 0.1651 1.04 0.861 1.26 PRS_PLINK_0.001 FALSE 618.5 Prolapse of vaginal vault after hysterectomy Female 94 1042 11 genitourinary black 1042, 94 260, 16 260, 27 260, 23 261, 28 0.0559 0.08 0.485 0.3142 1.06 0.904 1.24 0.514 0.318 0.106 0.9733 1.67 0.896 3.12 0.318 0.33 0.336 0.474 1.37 0.72 2.62 0.566 0.317 0.0738 1.132 1.76 0.947 3.28 PRS_PLINK_0.001 FALSE 618.6 Vaginal enterocele, congenital or acquired Female 122 1435 11 genitourinary black 1435, 122 359, 23 359, 41 358, 32 359, 26 0.0138 0.0671 0.837 0.07748 1.01 0.889 1.16 0.555 0.268 0.0383 1.417 1.74 1.03 2.95 0.312 0.277 0.26 0.5843 1.37 0.794 2.35 0.138 0.289 0.633 0.1984 1.15 0.652 2.02 PRS_PLINK_0.001 FALSE 619 Noninflammatory female genital disorders Female 1728 19112 11 genitourinary black 19112, 1728 4778, 444 4778, 421 4778, 401 4778, 462 0.0274 0.0187 0.143 0.844 1.03 0.991 1.07 -0.0527 0.071 0.457 0.3398 0.949 0.825 1.09 -0.101 0.0718 0.158 0.8022 0.904 0.785 1.04 0.0418 0.0695 0.547 0.2618 1.04 0.91 1.19 PRS_PLINK_0.001 FALSE 619.1 Noninflammatory disorders of ovary, fallopian tube, and broad ligament Female 159 1627 11 genitourinary black 1627, 159 407, 52 407, 31 406, 42 407, 34 0.0176 0.0491 0.719 0.143 1.02 0.924 1.12 -0.498 0.235 0.0343 1.464 0.608 0.383 0.964 -0.227 0.219 0.3 0.5231 0.797 0.52 1.22 -0.439 0.229 0.0555 1.255 0.645 0.412 1.01 PRS_PLINK_0.001 FALSE 619.2 Disorders of uterus, NEC Female 620 7117 11 genitourinary black 7117, 620 1780, 156 1779, 155 1779, 143 1779, 166 -0.00367 0.0425 0.931 0.03095 0.996 0.917 1.08 -0.00406 0.118 0.972 0.01211 0.996 0.791 1.25 -0.0879 0.12 0.465 0.333 0.916 0.724 1.16 0.0628 0.116 0.589 0.23 1.06 0.848 1.34 PRS_PLINK_0.001 FALSE 619.3 Noninflammatory disorders of cervix Female 576 6193 11 genitourinary black 6193, 576 1549, 140 1548, 153 1548, 128 1548, 155 0.0387 0.0342 0.257 0.5894 1.04 0.972 1.11 0.0918 0.122 0.452 0.3453 1.1 0.863 1.39 -0.0834 0.127 0.512 0.2911 0.92 0.717 1.18 0.103 0.122 0.396 0.4019 1.11 0.874 1.41 PRS_PLINK_0.001 FALSE 619.4 Noninflammatory disorders of vagina Female 316 3780 11 genitourinary black 3780, 316 945, 78 945, 74 945, 79 945, 85 -0.0125 0.0538 0.816 0.08835 0.988 0.889 1.1 -0.0669 0.168 0.69 0.1611 0.935 0.673 1.3 0.0167 0.165 0.92 0.03642 1.02 0.736 1.4 0.0819 0.162 0.613 0.2122 1.09 0.79 1.49 PRS_PLINK_0.001 FALSE 619.5 Noninflammatory disorders of vulva and perineum Female 266 2911 11 genitourinary black 2911, 266 728, 74 728, 63 727, 59 728, 70 0.101 0.0392 0.01 1.998 1.11 1.02 1.19 -0.178 0.178 0.32 0.4953 0.837 0.59 1.19 -0.228 0.181 0.207 0.6849 0.796 0.559 1.13 -0.0633 0.173 0.715 0.1456 0.939 0.668 1.32 PRS_PLINK_0.001 FALSE 620 Dysplasia of female genital organs Female 12 140 11 genitourinary black 140, 12 35, 3 35, 3 35, 4 35, 2 0.0449 0.801 0.955 0.01986 1.05 0.218 5.02 0.473 0.809 0.559 0.2529 1.61 0.329 7.84 0.384 0.77 0.618 0.2088 1.47 0.324 6.64 -0.0827 0.813 0.919 0.0367 0.921 0.187 4.53 PRS_PLINK_0.001 TRUE 621 Endometrial hyperplasia Female 232 2414 11 genitourinary black 2414, 232 604, 52 603, 61 603, 59 604, 60 -0.000932 0.0618 0.988 0.005259 0.999 0.885 1.13 0.153 0.195 0.432 0.3647 1.17 0.795 1.71 0.125 0.197 0.526 0.279 1.13 0.77 1.67 0.142 0.196 0.469 0.3292 1.15 0.785 1.69 PRS_PLINK_0.001 FALSE 622 Polyp of female genital organs Female 2245 22580 11 genitourinary black 22580, 2245 5644, 551 5645, 555 5645, 572 5645, 567 0.00602 0.0201 0.764 0.1167 1.01 0.967 1.05 0.00822 0.063 0.896 0.0476 1.01 0.891 1.14 0.0401 0.0625 0.521 0.283 1.04 0.921 1.18 0.028 0.0627 0.655 0.1834 1.03 0.909 1.16 PRS_PLINK_0.001 FALSE 622.1 Polyp of corpus uteri Female 1689 16858 11 genitourinary black 16858, 1689 4214, 402 4214, 422 4214, 421 4215, 444 0.000584 0.0248 0.981 0.008238 1 0.953 1.05 0.0496 0.0729 0.496 0.3043 1.05 0.911 1.21 0.0477 0.073 0.513 0.2897 1.05 0.909 1.21 0.1 0.0721 0.165 0.7815 1.11 0.96 1.27 PRS_PLINK_0.001 FALSE 622.2 Mucous polyp of cervix Female 726 7336 11 genitourinary black 7336, 726 1834, 196 1834, 171 1834, 187 1834, 172 0.0356 0.0277 0.199 0.7004 1.04 0.981 1.09 -0.138 0.109 0.208 0.6818 0.871 0.703 1.08 -0.0477 0.107 0.656 0.1829 0.953 0.773 1.18 -0.131 0.109 0.23 0.6388 0.877 0.708 1.09 PRS_PLINK_0.001 FALSE 623 Hypertrophy of female genital organs Female 271 2837 11 genitourinary black 2837, 271 710, 60 709, 75 709, 73 709, 63 0.000587 0.0834 0.994 0.002443 1 0.85 1.18 0.217 0.18 0.229 0.641 1.24 0.873 1.77 0.211 0.181 0.244 0.6134 1.23 0.866 1.76 0.0505 0.187 0.787 0.1041 1.05 0.729 1.52 PRS_PLINK_0.001 FALSE 624 Symptoms involving female genital tract Female 153 1623 11 genitourinary black 1623, 153 406, 38 406, 46 405, 37 406, 32 -0.321 0.273 0.239 0.6207 0.725 0.425 1.24 0.164 0.228 0.472 0.3262 1.18 0.753 1.84 -0.0286 0.239 0.905 0.04349 0.972 0.608 1.55 -0.204 0.247 0.409 0.3888 0.815 0.503 1.32 PRS_PLINK_0.001 FALSE 624.1 Dystrophy of female genital tract Female 41 531 11 genitourinary black 531, 41 133, 9 133, 13 132, 8 133, 11 0.072 0.105 0.492 0.3082 1.07 0.875 1.32 0.277 0.435 0.524 0.2807 1.32 0.563 3.09 -0.217 0.5 0.665 0.1773 0.805 0.302 2.15 0.0953 0.449 0.832 0.07991 1.1 0.456 2.65 PRS_PLINK_0.001 TRUE 624.2 Atrophy of female genital tract Female 94 892 11 genitourinary black 892, 94 223, 19 223, 30 223, 29 223, 16 -0.426 0.357 0.232 0.6337 0.653 0.325 1.31 0.459 0.303 0.13 0.8873 1.58 0.874 2.86 0.444 0.308 0.15 0.825 1.56 0.852 2.85 -0.117 0.342 0.731 0.1358 0.889 0.455 1.74 PRS_PLINK_0.001 FALSE 624.9 stress incontinence, female Female 1053 12443 11 genitourinary black 12443, 1053 3111, 236 3111, 273 3110, 269 3111, 275 -0.0152 0.0335 0.651 0.1864 0.985 0.922 1.05 0.15 0.0923 0.105 0.98 1.16 0.969 1.39 0.131 0.0925 0.156 0.8075 1.14 0.951 1.37 0.157 0.0921 0.0892 1.05 1.17 0.976 1.4 PRS_PLINK_0.001 FALSE 625 Pain and other symptoms associated with female genital organs Female 555 6478 11 genitourinary black 6478, 555 1620, 116 1619, 138 1619, 155 1620, 146 0.0524 0.0295 0.0756 1.121 1.05 0.995 1.12 0.178 0.13 0.172 0.7633 1.19 0.925 1.54 0.287 0.127 0.0238 1.623 1.33 1.04 1.71 0.236 0.129 0.0663 1.179 1.27 0.984 1.63 PRS_PLINK_0.001 FALSE 625.1 Dyspareunia Female 219 2760 11 genitourinary black 2760, 219 690, 47 690, 49 690, 61 690, 62 0.0114 0.0728 0.875 0.05777 1.01 0.877 1.17 0.0481 0.208 0.817 0.08761 1.05 0.698 1.58 0.256 0.199 0.2 0.6998 1.29 0.874 1.91 0.265 0.199 0.183 0.7373 1.3 0.882 1.92 PRS_PLINK_0.001 FALSE 626 Disorders of menstruation and other abnormal bleeding from female genital tract Female 3505 26521 11 genitourinary black 26521, 3505 6631, 857 6630, 864 6630, 870 6630, 914 -0.0292 0.0211 0.166 0.7796 0.971 0.932 1.01 0.00607 0.0515 0.906 0.04277 1.01 0.909 1.11 0.017 0.0514 0.741 0.1301 1.02 0.92 1.12 0.0627 0.0509 0.218 0.6618 1.06 0.964 1.18 PRS_PLINK_0.001 FALSE 626.1 Irregular menstrual cycle/bleeding Female 3032 25447 11 genitourinary black 25447, 3032 6362, 733 6362, 758 6361, 755 6362, 786 -0.0208 0.0211 0.324 0.4889 0.979 0.94 1.02 0.027 0.0548 0.623 0.2054 1.03 0.923 1.14 0.0288 0.0549 0.599 0.2225 1.03 0.924 1.15 0.0658 0.0544 0.227 0.6444 1.07 0.96 1.19 PRS_PLINK_0.001 FALSE 626.11 Absent or infrequent menstruation Female 22 249 11 genitourinary black 249, 22 63, 5 62, 4 62, 9 62, 4 0.068 0.123 0.579 0.2371 1.07 0.842 1.36 -0.178 0.638 0.78 0.1081 0.837 0.24 2.92 0.744 0.567 0.19 0.7217 2.1 0.692 6.4 -0.152 0.614 0.805 0.09414 0.859 0.258 2.86 PRS_PLINK_0.001 TRUE 626.12 Excessive or frequent menstruation Female 1944 20935 11 genitourinary black 20935, 1944 5234, 491 5234, 459 5233, 497 5234, 497 -0.0335 0.0282 0.235 0.6291 0.967 0.915 1.02 -0.0688 0.0677 0.31 0.509 0.933 0.817 1.07 0.0121 0.0665 0.856 0.06764 1.01 0.888 1.15 0.00953 0.0665 0.886 0.05255 1.01 0.886 1.15 PRS_PLINK_0.001 FALSE 626.13 Irregular menstrual cycle Female 381 4333 11 genitourinary black 4333, 381 1084, 85 1083, 90 1083, 92 1083, 114 -0.00786 0.0507 0.877 0.05708 0.992 0.898 1.1 0.0754 0.156 0.629 0.2011 1.08 0.794 1.46 0.0887 0.155 0.568 0.2456 1.09 0.806 1.48 0.286 0.149 0.0542 1.266 1.33 0.995 1.78 PRS_PLINK_0.001 FALSE 626.14 Irregular menstrual bleeding Female 828 8771 11 genitourinary black 8771, 828 2193, 189 2193, 219 2192, 210 2193, 210 0.00164 0.0355 0.963 0.01632 1 0.934 1.07 0.145 0.103 0.162 0.7917 1.16 0.944 1.42 0.108 0.104 0.3 0.5231 1.11 0.908 1.37 0.102 0.104 0.329 0.4829 1.11 0.902 1.36 PRS_PLINK_0.001 FALSE 626.2 Dysmenorrhea Female 318 4133 11 genitourinary black 4133, 318 1034, 86 1033, 82 1033, 79 1033, 71 -0.0677 0.109 0.536 0.2706 0.935 0.754 1.16 -0.0536 0.16 0.737 0.1326 0.948 0.693 1.3 -0.0849 0.161 0.597 0.224 0.919 0.67 1.26 -0.199 0.165 0.228 0.6411 0.82 0.593 1.13 PRS_PLINK_0.001 FALSE 626.4 Premenstrual tension syndromes Female 27 383 11 genitourinary black 383, 27 96, 3 96, 6 95, 11 96, 7 0.816 0.595 0.17 0.7693 2.26 0.705 7.26 0.581 0.629 0.356 0.4489 1.79 0.521 6.13 1.32 0.616 0.0323 1.49 3.74 1.12 12.5 0.589 0.629 0.349 0.457 1.8 0.525 6.18 PRS_PLINK_0.001 TRUE 626.8 Infertility, female Female 316 3109 11 genitourinary black 3109, 316 778, 83 777, 72 777, 85 777, 76 -0.0421 0.083 0.612 0.2136 0.959 0.815 1.13 -0.14 0.168 0.405 0.3923 0.87 0.626 1.21 0.0237 0.162 0.883 0.05394 1.02 0.746 1.41 -0.0969 0.166 0.56 0.2522 0.908 0.656 1.26 PRS_PLINK_0.001 FALSE 627 Menopausal and postmenopausal disorders Female 2087 21723 11 genitourinary black 21723, 2087 5430, 495 5431, 526 5430, 530 5431, 536 0.00608 0.0203 0.764 0.1168 1.01 0.967 1.05 0.0634 0.0654 0.332 0.4784 1.07 0.937 1.21 0.0689 0.0653 0.292 0.5351 1.07 0.943 1.22 0.0778 0.0652 0.233 0.6331 1.08 0.951 1.23 PRS_PLINK_0.001 FALSE 627.1 Postmenopausal bleeding Female 1795 18645 11 genitourinary black 18645, 1795 4662, 437 4661, 456 4661, 458 4661, 444 0.00583 0.0211 0.782 0.1067 1.01 0.965 1.05 0.0449 0.07 0.521 0.2832 1.05 0.912 1.2 0.0491 0.0699 0.483 0.3162 1.05 0.916 1.2 0.0152 0.0704 0.83 0.0811 1.02 0.884 1.17 PRS_PLINK_0.001 FALSE 627.2 Symptomatic menopause Female 34 390 11 genitourinary black 390, 34 98, 8 97, 12 97, 11 98, 3 -0.628 0.596 0.293 0.5337 0.534 0.166 1.72 0.325 0.46 0.479 0.3195 1.38 0.562 3.41 0.304 0.459 0.507 0.2948 1.36 0.552 3.33 -0.736 0.612 0.229 0.6395 0.479 0.144 1.59 PRS_PLINK_0.001 TRUE 627.3 Postmenopausal atrophic vaginitis Female 209 2200 11 genitourinary black 2200, 209 550, 46 550, 43 550, 62 550, 58 0.0502 0.0721 0.487 0.3128 1.05 0.913 1.21 -0.0622 0.217 0.775 0.111 0.94 0.614 1.44 0.296 0.202 0.142 0.8477 1.34 0.906 2 0.221 0.205 0.28 0.5529 1.25 0.835 1.86 PRS_PLINK_0.001 FALSE 627.4 Premenopausal menorrhagia Female 58 701 11 genitourinary black 701, 58 176, 16 175, 10 175, 19 175, 13 0.199 0.408 0.626 0.2031 1.22 0.548 2.72 -0.471 0.401 0.24 0.6197 0.624 0.285 1.37 0.117 0.346 0.736 0.1331 1.12 0.571 2.21 -0.284 0.377 0.45 0.3465 0.752 0.36 1.57 PRS_PLINK_0.001 FALSE 628 Ovarian cyst Female 932 10549 11 genitourinary black 10549, 932 2638, 248 2637, 200 2637, 250 2637, 234 -0.023 0.041 0.574 0.241 0.977 0.902 1.06 -0.214 0.0987 0.0304 1.517 0.808 0.666 0.98 0.00998 0.0935 0.915 0.03855 1.01 0.841 1.21 -0.0562 0.095 0.554 0.2565 0.945 0.785 1.14 PRS_PLINK_0.001 FALSE 634 Miscarriage; stillbirth Female 1257 8400 12 pregnancy complications royalblue4 8400, 1257 2100, 324 2100, 317 2100, 306 2100, 310 0.00609 0.0323 0.85 0.07034 1.01 0.944 1.07 -0.0436 0.0855 0.61 0.2146 0.957 0.81 1.13 -0.059 0.0862 0.494 0.3065 0.943 0.796 1.12 -0.0415 0.0859 0.629 0.2013 0.959 0.811 1.14 PRS_PLINK_0.001 FALSE 634.1 Missed abortion/Hydatidiform mole Female 271 2598 12 pregnancy complications royalblue4 2598, 271 650, 86 649, 54 649, 68 650, 63 0.0459 0.0426 0.282 0.5504 1.05 0.963 1.14 -0.46 0.181 0.0109 1.961 0.632 0.443 0.9 -0.236 0.17 0.165 0.7818 0.789 0.565 1.1 -0.31 0.174 0.0738 1.132 0.733 0.522 1.03 PRS_PLINK_0.001 FALSE 634.3 Ectopic pregnancy Female 74 763 12 pregnancy complications royalblue4 763, 74 191, 18 191, 16 190, 22 191, 18 0.0158 0.0823 0.847 0.07187 1.02 0.865 1.19 -0.163 0.349 0.64 0.1936 0.85 0.429 1.68 0.158 0.33 0.632 0.1995 1.17 0.614 2.24 0.0191 0.34 0.955 0.01984 1.02 0.523 1.99 PRS_PLINK_0.001 FALSE 635 Hemorrhage during pregnancy; childbirth and postpartum Female 517 4113 12 pregnancy complications royalblue4 4113, 517 1029, 121 1028, 131 1028, 115 1028, 150 0.0301 0.0437 0.491 0.3086 1.03 0.946 1.12 0.0628 0.133 0.638 0.1953 1.06 0.82 1.38 -0.0437 0.137 0.75 0.125 0.957 0.732 1.25 0.213 0.13 0.0999 1.001 1.24 0.96 1.6 PRS_PLINK_0.001 FALSE 635.2 Antepartum hemorrhage, abruptio placentae, and placenta previa Female 215 2069 12 pregnancy complications royalblue4 2069, 215 518, 52 517, 63 517, 42 517, 58 -0.0145 0.0748 0.847 0.07227 0.986 0.851 1.14 0.158 0.196 0.42 0.3763 1.17 0.797 1.72 -0.216 0.215 0.315 0.5015 0.806 0.529 1.23 0.121 0.199 0.544 0.2646 1.13 0.764 1.67 PRS_PLINK_0.001 FALSE 635.3 Placenta previa and abruptio placenta Female 339 2942 12 pregnancy complications royalblue4 2942, 339 736, 79 735, 77 735, 77 736, 106 0.0492 0.0455 0.279 0.554 1.05 0.961 1.15 -0.0193 0.167 0.908 0.04179 0.981 0.707 1.36 -0.0176 0.167 0.916 0.0381 0.983 0.708 1.36 0.295 0.157 0.0597 1.224 1.34 0.988 1.83 PRS_PLINK_0.001 FALSE 636 Early or threatened labor; hemorrhage in early pregnancy Female 593 4708 12 pregnancy complications royalblue4 4708, 593 1177, 152 1177, 162 1177, 124 1177, 155 -0.00602 0.0481 0.901 0.04549 0.994 0.904 1.09 0.0445 0.12 0.712 0.1477 1.05 0.826 1.32 -0.197 0.128 0.122 0.9143 0.821 0.639 1.05 0.0192 0.121 0.874 0.05831 1.02 0.803 1.29 PRS_PLINK_0.001 FALSE 636.2 Early onset of delivery Female 167 1507 12 pregnancy complications royalblue4 1507, 167 377, 42 377, 45 376, 26 377, 54 0.0724 0.054 0.18 0.7437 1.08 0.967 1.2 0.0788 0.224 0.725 0.1395 1.08 0.697 1.68 -0.466 0.256 0.0691 1.16 0.627 0.38 1.04 0.294 0.218 0.177 0.7516 1.34 0.875 2.06 PRS_PLINK_0.001 FALSE 636.3 Hemorrhage in early pregnancy Female 249 2494 12 pregnancy complications royalblue4 2494, 249 624, 56 623, 67 623, 60 624, 66 -0.0211 0.0707 0.766 0.116 0.979 0.852 1.12 0.175 0.188 0.353 0.4525 1.19 0.824 1.72 0.0743 0.192 0.699 0.1555 1.08 0.739 1.57 0.153 0.189 0.418 0.379 1.17 0.805 1.69 PRS_PLINK_0.001 FALSE 638 Other high-risk pregnancy Female 16 168 12 pregnancy complications royalblue4 168, 16 42, 4 42, 5 42, 3 42, 4 0.198 0.853 0.816 0.08806 1.22 0.229 6.49 -0.0432 0.708 0.951 0.02167 0.958 0.239 3.84 -0.339 0.711 0.633 0.1984 0.712 0.177 2.87 0.062 0.71 0.93 0.03133 1.06 0.265 4.28 PRS_PLINK_0.001 TRUE 642 Hypertension complicating pregnancy, childbirth, and the puerperium Female 260 2616 12 pregnancy complications royalblue4 2616, 260 654, 71 654, 62 654, 53 654, 74 0.0473 0.0508 0.352 0.4535 1.05 0.949 1.16 -0.137 0.181 0.448 0.3489 0.872 0.612 1.24 -0.294 0.188 0.119 0.9263 0.745 0.515 1.08 0.0446 0.174 0.797 0.09827 1.05 0.744 1.47 PRS_PLINK_0.001 FALSE 642.1 Preeclampsia and eclampsia Female 72 751 12 pregnancy complications royalblue4 751, 72 188, 17 188, 18 187, 11 188, 26 0.121 0.0721 0.0931 1.031 1.13 0.98 1.3 0.0886 0.351 0.801 0.09655 1.09 0.549 2.17 -0.459 0.388 0.237 0.6252 0.632 0.295 1.35 0.473 0.324 0.145 0.8398 1.61 0.85 3.03 PRS_PLINK_0.001 FALSE 643 Excessive vomiting in pregnancy Female 50 566 12 pregnancy complications royalblue4 566, 50 142, 12 141, 9 141, 15 142, 14 0.0683 0.114 0.549 0.2606 1.07 0.856 1.34 -0.304 0.439 0.489 0.3108 0.738 0.312 1.74 0.219 0.389 0.574 0.2408 1.24 0.58 2.67 0.193 0.398 0.628 0.202 1.21 0.556 2.64 PRS_PLINK_0.001 TRUE 643.1 Hyperemesis gravidarum Female 38 359 12 pregnancy complications royalblue4 359, 38 90, 9 90, 7 89, 11 90, 11 0.0413 0.117 0.725 0.1397 1.04 0.828 1.31 -0.28 0.512 0.584 0.2335 0.756 0.277 2.06 0.227 0.46 0.622 0.2065 1.26 0.509 3.09 0.213 0.456 0.641 0.1934 1.24 0.506 3.03 PRS_PLINK_0.001 TRUE 645 Late pregnancy and failed induction Female 328 3015 12 pregnancy complications royalblue4 3015, 328 754, 85 754, 79 753, 70 754, 94 0.00254 0.0653 0.969 0.01368 1 0.882 1.14 -0.0695 0.164 0.671 0.173 0.933 0.676 1.29 -0.19 0.168 0.259 0.5873 0.827 0.595 1.15 0.106 0.158 0.501 0.3002 1.11 0.816 1.51 PRS_PLINK_0.001 FALSE 646 Other complications of pregnancy NEC Female 524 5008 12 pregnancy complications royalblue4 5008, 524 1252, 117 1252, 138 1252, 127 1252, 142 -0.025 0.0596 0.676 0.1703 0.975 0.868 1.1 0.168 0.131 0.201 0.6975 1.18 0.914 1.53 0.0711 0.134 0.595 0.2254 1.07 0.826 1.4 0.193 0.131 0.139 0.8564 1.21 0.939 1.57 PRS_PLINK_0.001 FALSE 647 Infectious and parasitic complications affecting pregnancy Female 10 148 12 pregnancy complications royalblue4 148, 10 37, 1 37, 5 37, 2 37, 2 0.189 1.16 0.871 0.05988 1.21 0.124 11.8 1.16 0.871 0.184 0.734 3.18 0.576 17.5 0.638 1.14 0.574 0.2411 1.89 0.205 17.5 0.912 1.03 0.374 0.4273 2.49 0.333 18.6 PRS_PLINK_0.001 TRUE 647.1 Infections of genitourinary tract during pregnancy Female 62 665 12 pregnancy complications royalblue4 665, 62 167, 7 166, 15 166, 18 166, 22 0.0504 0.0748 0.501 0.3004 1.05 0.908 1.22 0.753 0.443 0.0894 1.049 2.12 0.891 5.06 0.858 0.436 0.0492 1.308 2.36 1 5.55 1.15 0.426 0.00676 2.17 3.17 1.38 7.32 PRS_PLINK_0.001 FALSE 649 Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium Female 31 282 12 pregnancy complications royalblue4 282, 31 71, 10 70, 8 70, 7 71, 6 -0.537 0.635 0.397 0.4011 0.584 0.168 2.03 -0.154 0.491 0.754 0.1228 0.857 0.327 2.25 -0.232 0.494 0.638 0.1949 0.793 0.301 2.09 -0.419 0.518 0.419 0.3777 0.658 0.238 1.82 PRS_PLINK_0.001 TRUE 649.1 Diabetes or abnormal glucose tolerance complicating pregnancy Female 49 451 12 pregnancy complications royalblue4 451, 49 113, 18 113, 11 112, 11 113, 9 -1.02 0.519 0.0484 1.315 0.359 0.13 0.993 -0.444 0.397 0.264 0.5792 0.642 0.295 1.4 -0.517 0.396 0.192 0.7177 0.596 0.274 1.3 -0.667 0.416 0.109 0.9634 0.513 0.227 1.16 PRS_PLINK_0.001 TRUE 650 Normal delivery Female 484 4626 12 pregnancy complications royalblue4 4626, 484 1157, 129 1156, 114 1156, 124 1157, 117 0.00571 0.0447 0.898 0.04659 1.01 0.921 1.1 -0.127 0.135 0.345 0.4619 0.881 0.676 1.15 -0.0372 0.132 0.778 0.1091 0.963 0.744 1.25 -0.0993 0.134 0.458 0.3394 0.905 0.697 1.18 PRS_PLINK_0.001 FALSE 651 Multiple gestation Female 96 825 12 pregnancy complications royalblue4 825, 96 207, 23 206, 25 206, 20 206, 28 -0.0208 0.0793 0.793 0.1009 0.979 0.838 1.14 0.0557 0.302 0.854 0.06867 1.06 0.585 1.91 -0.182 0.319 0.568 0.2457 0.833 0.445 1.56 0.165 0.296 0.577 0.2386 1.18 0.66 2.11 PRS_PLINK_0.001 FALSE 652 Malposition and malpresentation of fetus or obstruction Female 458 3928 12 pregnancy complications royalblue4 3928, 458 982, 134 982, 106 982, 97 982, 121 0.0013 0.0537 0.981 0.00845 1 0.901 1.11 -0.256 0.137 0.0625 1.204 0.774 0.591 1.01 -0.326 0.14 0.0203 1.694 0.722 0.549 0.951 -0.106 0.133 0.425 0.3721 0.899 0.693 1.17 PRS_PLINK_0.001 FALSE 653 Problems associated with amniotic cavity and membranes Female 337 3295 12 pregnancy complications royalblue4 3295, 337 824, 104 824, 97 823, 66 824, 70 -0.00124 0.0646 0.985 0.006704 0.999 0.88 1.13 -0.0585 0.149 0.694 0.1584 0.943 0.705 1.26 -0.441 0.164 0.00724 2.141 0.643 0.466 0.888 -0.391 0.161 0.0151 1.821 0.676 0.493 0.927 PRS_PLINK_0.001 FALSE 654 Other and unspecified complications of birth; puerperium affecting management of mother Female 13 176 12 pregnancy complications royalblue4 176, 13 44, 5 44, 3 44, 4 44, 1 -1.5 0.978 0.125 0.9041 0.223 0.0328 1.51 -0.295 0.679 0.664 0.1779 0.745 0.197 2.82 -0.276 0.697 0.691 0.1603 0.758 0.194 2.97 -1.11 0.853 0.192 0.7175 0.328 0.0617 1.75 PRS_PLINK_0.001 TRUE 655 Known or suspected fetal abnormality affecting management of mother Female 1147 6855 12 pregnancy complications royalblue4 6855, 1147 1714, 309 1714, 279 1713, 270 1714, 289 -0.00491 0.0397 0.902 0.04498 0.995 0.921 1.08 -0.125 0.0901 0.165 0.7824 0.882 0.74 1.05 -0.142 0.0907 0.119 0.9251 0.868 0.727 1.04 -0.0624 0.0896 0.486 0.3133 0.94 0.788 1.12 PRS_PLINK_0.001 FALSE 656 Other perinatal conditions of fetus or newborn Both 29 257 12 pregnancy complications royalblue4 257, 29 65, 11 64, 10 64, 4 64, 4 -1.59 0.693 0.0221 1.655 0.205 0.0527 0.797 -0.108 0.461 0.814 0.08931 0.897 0.364 2.21 -0.89 0.562 0.113 0.9472 0.411 0.137 1.23 -1.08 0.594 0.0702 1.154 0.341 0.107 1.09 PRS_PLINK_0.001 TRUE 661 Fetal distress and abnormal forces of labor Female 622 4271 12 pregnancy complications royalblue4 4271, 622 1068, 175 1068, 153 1067, 144 1068, 150 -0.0883 0.0845 0.296 0.5284 0.915 0.776 1.08 -0.14 0.119 0.241 0.6188 0.87 0.689 1.1 -0.188 0.121 0.12 0.9209 0.829 0.654 1.05 -0.146 0.119 0.222 0.6532 0.864 0.684 1.09 PRS_PLINK_0.001 FALSE 663 Umbilical cord complications during labor and delivery Female 127 1223 12 pregnancy complications royalblue4 1223, 127 306, 45 306, 31 305, 19 306, 32 0.0748 0.0748 0.317 0.4987 1.08 0.931 1.25 -0.374 0.244 0.126 0.9001 0.688 0.426 1.11 -0.873 0.281 0.00189 2.724 0.418 0.241 0.724 -0.377 0.244 0.121 0.9157 0.686 0.426 1.11 PRS_PLINK_0.001 FALSE 665 Obstetrical/birth trauma Female 1404 6778 12 pregnancy complications royalblue4 6778, 1404 1695, 360 1694, 372 1694, 326 1695, 346 -0.0111 0.0327 0.735 0.1339 0.989 0.928 1.05 -0.00654 0.0833 0.937 0.02807 0.993 0.844 1.17 -0.105 0.0853 0.217 0.6644 0.9 0.761 1.06 -0.0525 0.0844 0.534 0.2728 0.949 0.804 1.12 PRS_PLINK_0.001 FALSE 669 Complications of labor and delivery NEC Female 677 4892 12 pregnancy complications royalblue4 4892, 677 1223, 185 1223, 171 1223, 158 1223, 163 -0.174 0.12 0.147 0.8326 0.841 0.665 1.06 -0.0881 0.114 0.438 0.3583 0.916 0.733 1.14 -0.152 0.116 0.188 0.7259 0.859 0.684 1.08 -0.127 0.115 0.268 0.5723 0.88 0.703 1.1 PRS_PLINK_0.001 FALSE 671 Venous/cerebrovascular complications embolism in pregnancy and the puerperium Female 49 369 12 pregnancy complications royalblue4 369, 49 93, 14 92, 6 92, 15 92, 14 0.0591 0.113 0.601 0.2212 1.06 0.85 1.32 -0.854 0.494 0.0842 1.075 0.426 0.162 1.12 0.0965 0.398 0.809 0.09224 1.1 0.504 2.4 0.0517 0.4 0.897 0.04717 1.05 0.481 2.31 PRS_PLINK_0.001 TRUE 674 Other complications of the puerperium NEC Female 55 628 12 pregnancy complications royalblue4 628, 55 157, 12 157, 16 157, 9 157, 18 0.0676 0.108 0.533 0.2733 1.07 0.865 1.32 0.329 0.385 0.393 0.4056 1.39 0.653 2.96 -0.143 0.447 0.749 0.1253 0.867 0.361 2.08 0.378 0.38 0.319 0.4955 1.46 0.693 3.07 PRS_PLINK_0.001 FALSE 676 Other disorders of the breast associated with childbirth and disorders of lactation Female 13 134 12 pregnancy complications royalblue4 134, 13 34, 3 33, 3 33, 2 34, 5 0.408 0.965 0.672 0.1726 1.5 0.227 9.97 0.207 0.81 0.799 0.09763 1.23 0.251 6.02 -0.0896 0.878 0.919 0.03682 0.914 0.164 5.11 0.414 0.72 0.565 0.248 1.51 0.369 6.2 PRS_PLINK_0.001 TRUE 679 Complications of in utero procedures Female 17 121 13 dermatologic firebrick 121, 17 31, 7 30, 4 30, 2 30, 4 -0.722 0.853 0.397 0.4012 0.486 0.0913 2.58 -0.515 0.708 0.467 0.331 0.597 0.149 2.39 -0.848 0.811 0.296 0.5291 0.428 0.0875 2.1 -0.179 0.678 0.792 0.1011 0.836 0.221 3.16 PRS_PLINK_0.001 TRUE 681 Superficial cellulitis and abscess Both 1180 15338 13 dermatologic firebrick 15338, 1180 3835, 282 3834, 298 3834, 292 3835, 308 0.0188 0.0235 0.423 0.3735 1.02 0.973 1.07 0.0533 0.0859 0.535 0.2715 1.05 0.891 1.25 0.0302 0.0864 0.727 0.1386 1.03 0.87 1.22 0.0834 0.0853 0.328 0.4836 1.09 0.92 1.28 PRS_PLINK_0.001 FALSE 681.1 Cellulitis and abscess of fingers/toes Both 84 1202 13 dermatologic firebrick 1202, 84 301, 24 300, 19 300, 12 301, 29 0.0824 0.114 0.47 0.3281 1.09 0.868 1.36 -0.233 0.309 0.451 0.3459 0.792 0.432 1.45 -0.698 0.348 0.0446 1.351 0.498 0.252 0.983 0.12 0.282 0.67 0.1738 1.13 0.649 1.96 PRS_PLINK_0.001 FALSE 681.2 Cellulitis and abscess of face/neck Both 116 1124 13 dermatologic firebrick 1124, 116 281, 30 281, 23 281, 38 281, 25 0.0931 0.055 0.0905 1.044 1.1 0.985 1.22 -0.252 0.283 0.373 0.4286 0.777 0.447 1.35 0.214 0.255 0.401 0.3965 1.24 0.751 2.04 -0.209 0.278 0.452 0.345 0.811 0.471 1.4 PRS_PLINK_0.001 FALSE 681.3 Cellulitis and abscess of arm/hand Both 858 11671 13 dermatologic firebrick 11671, 858 2918, 195 2918, 209 2917, 225 2918, 229 0.01 0.03 0.738 0.1319 1.01 0.952 1.07 0.0683 0.103 0.505 0.2967 1.07 0.876 1.31 0.14 0.101 0.166 0.7788 1.15 0.943 1.4 0.157 0.101 0.12 0.9225 1.17 0.96 1.42 PRS_PLINK_0.001 FALSE 681.5 Cellulitis and abscess of leg, except foot Both 860 11676 13 dermatologic firebrick 11676, 860 2919, 197 2919, 209 2919, 226 2919, 228 0.011 0.0302 0.715 0.1456 1.01 0.953 1.07 0.058 0.102 0.571 0.2437 1.06 0.867 1.29 0.133 0.101 0.186 0.7309 1.14 0.938 1.39 0.142 0.1 0.156 0.807 1.15 0.947 1.4 PRS_PLINK_0.001 FALSE 681.6 Cellulitis and abscess of foot, toe Both 854 11593 13 dermatologic firebrick 11593, 854 2899, 196 2898, 206 2898, 226 2898, 226 0.012 0.0303 0.692 0.1596 1.01 0.954 1.07 0.0489 0.103 0.634 0.1979 1.05 0.859 1.28 0.139 0.101 0.169 0.7723 1.15 0.943 1.4 0.138 0.101 0.171 0.7674 1.15 0.942 1.4 PRS_PLINK_0.001 FALSE 681.7 Cellulitis and abscess of trunk Both 102 1275 13 dermatologic firebrick 1275, 102 319, 31 319, 30 318, 22 319, 19 0.0203 0.0717 0.777 0.1095 1.02 0.887 1.17 -0.055 0.265 0.835 0.0782 0.946 0.564 1.59 -0.311 0.282 0.271 0.5678 0.733 0.422 1.27 -0.498 0.294 0.0905 1.043 0.608 0.342 1.08 PRS_PLINK_0.001 FALSE 686 Other local infections of skin and subcutaneous tissue Both 232 2829 13 dermatologic firebrick 2829, 232 708, 58 707, 55 707, 59 707, 60 0.0884 0.0329 0.00729 2.138 1.09 1.02 1.17 -0.0535 0.193 0.782 0.1068 0.948 0.649 1.38 0.0259 0.19 0.892 0.04963 1.03 0.707 1.49 0.0291 0.189 0.878 0.05661 1.03 0.71 1.49 PRS_PLINK_0.001 FALSE 686.1 Carbuncle and furuncle Both 386 5028 13 dermatologic firebrick 5028, 386 1257, 96 1257, 100 1257, 87 1257, 103 0.0365 0.0287 0.204 0.6906 1.04 0.98 1.1 0.0404 0.147 0.784 0.1058 1.04 0.78 1.39 -0.0897 0.152 0.556 0.2552 0.914 0.678 1.23 0.0938 0.147 0.523 0.2814 1.1 0.824 1.46 PRS_PLINK_0.001 FALSE 686.3 Pilonidal cyst Both 103 1274 13 dermatologic firebrick 1274, 103 319, 24 318, 16 318, 30 319, 33 0.0529 0.0758 0.486 0.3138 1.05 0.909 1.22 -0.441 0.323 0.172 0.7639 0.644 0.342 1.21 0.2 0.282 0.478 0.3208 1.22 0.703 2.12 0.323 0.274 0.239 0.6225 1.38 0.807 2.36 PRS_PLINK_0.001 FALSE 686.4 Pyogenic granuloma Both 90 761 13 dermatologic firebrick 761, 90 191, 24 190, 23 190, 17 190, 26 0.0115 0.0858 0.893 0.04906 1.01 0.855 1.2 -0.0754 0.306 0.806 0.09386 0.927 0.509 1.69 -0.337 0.325 0.299 0.5241 0.714 0.377 1.35 0.0419 0.296 0.887 0.05185 1.04 0.584 1.86 PRS_PLINK_0.001 FALSE 687 Symptoms affecting skin Both 115 1238 13 dermatologic firebrick 1238, 115 310, 29 309, 26 309, 28 310, 32 0.047 0.0505 0.352 0.4535 1.05 0.949 1.16 -0.101 0.276 0.714 0.1466 0.904 0.526 1.55 -0.0491 0.277 0.859 0.06591 0.952 0.554 1.64 0.0938 0.265 0.724 0.1404 1.1 0.653 1.85 PRS_PLINK_0.001 FALSE 687.1 Rash and other nonspecific skin eruption Both 375 4577 13 dermatologic firebrick 4577, 375 1144, 72 1144, 110 1144, 94 1144, 99 0.0498 0.0422 0.238 0.6227 1.05 0.968 1.14 0.428 0.156 0.00605 2.218 1.53 1.13 2.08 0.258 0.161 0.108 0.9652 1.29 0.945 1.77 0.312 0.159 0.0495 1.305 1.37 1 1.87 PRS_PLINK_0.001 FALSE 687.2 Localized superficial swelling, mass, or lump Both 63 666 13 dermatologic firebrick 666, 63 167, 16 166, 13 166, 18 167, 16 0.179 0.114 0.114 0.9433 1.2 0.958 1.49 -0.144 0.375 0.701 0.1546 0.866 0.415 1.8 0.0898 0.353 0.799 0.09747 1.09 0.548 2.18 -0.0421 0.358 0.906 0.04279 0.959 0.476 1.93 PRS_PLINK_0.001 FALSE 687.3 Changes in skin texture Both 19 238 13 dermatologic firebrick 238, 19 60, 7 59, 4 59, 4 60, 4 -0.45 0.613 0.463 0.3347 0.638 0.192 2.12 -0.501 0.624 0.422 0.3743 0.606 0.178 2.06 -0.626 0.6 0.297 0.527 0.535 0.165 1.73 PRS_PLINK_0.001 TRUE 687.4 Disturbance of skin sensation Both 454 6308 13 dermatologic firebrick 6308, 454 1577, 101 1577, 133 1577, 105 1577, 115 -0.0748 0.0919 0.415 0.3815 0.928 0.775 1.11 0.265 0.136 0.0513 1.29 1.3 0.999 1.7 0.0441 0.143 0.757 0.1207 1.05 0.79 1.38 0.132 0.14 0.345 0.4623 1.14 0.867 1.5 PRS_PLINK_0.001 FALSE 689 Disorder of skin and subcutaneous tissue NOS Both 1177 12093 13 dermatologic firebrick 12093, 1177 3023, 324 3023, 277 3023, 288 3023, 288 0.0284 0.0246 0.248 0.6057 1.03 0.98 1.08 -0.155 0.0856 0.0694 1.159 0.856 0.724 1.01 -0.121 0.0848 0.155 0.8085 0.886 0.751 1.05 -0.114 0.0849 0.177 0.7511 0.892 0.755 1.05 PRS_PLINK_0.001 FALSE 690 Erythematosquamous dermatosis Both 12 142 13 dermatologic firebrick 142, 12 36, 1 35, 5 35, 3 36, 3 0.425 0.474 0.37 0.4318 1.53 0.604 3.88 1.32 0.846 0.118 0.9282 3.75 0.715 19.7 0.88 1.11 0.428 0.3683 2.41 0.273 21.2 0.726 0.976 0.457 0.3401 2.07 0.305 14 PRS_PLINK_0.001 TRUE 690.1 Seborrheic dermatitis Both 10 108 13 dermatologic firebrick 108, 10 27, 1 27, 5 27, 3 27, 1 -0.0911 0.941 0.923 0.03487 0.913 0.144 5.77 1.55 0.941 0.0991 1.004 4.72 0.746 29.9 0.968 1.05 0.355 0.4496 2.63 0.338 20.5 0.142 1.08 0.896 0.0479 1.15 0.138 9.63 PRS_PLINK_0.001 TRUE 691 Congenital anomalies of skin Both 19 265 13 dermatologic firebrick 265, 19 67, 3 66, 5 66, 6 66, 5 0.415 0.791 0.6 0.222 1.51 0.321 7.13 0.449 0.686 0.513 0.2901 1.57 0.408 6.01 0.497 0.628 0.429 0.3674 1.64 0.48 5.63 0.407 0.679 0.55 0.26 1.5 0.397 5.69 PRS_PLINK_0.001 TRUE 694 Dyschromia and Vitiligo Both 201 2054 13 dermatologic firebrick 2054, 201 514, 44 513, 63 513, 56 514, 38 -0.0162 0.0869 0.853 0.06924 0.984 0.83 1.17 0.359 0.204 0.0781 1.107 1.43 0.96 2.13 0.226 0.208 0.278 0.5557 1.25 0.833 1.89 -0.144 0.226 0.524 0.2808 0.866 0.555 1.35 PRS_PLINK_0.001 FALSE 694.1 Vitiligo Both 15 130 13 dermatologic firebrick 130, 15 33, 1 32, 7 32, 5 33, 2 0.544 0.874 0.534 0.2726 1.72 0.311 9.55 1.34 0.827 0.106 0.9735 3.8 0.752 19.3 1.18 0.918 0.197 0.7051 3.27 0.541 19.7 0.517 0.942 0.583 0.2342 1.68 0.265 10.6 PRS_PLINK_0.001 TRUE 694.2 Other dyschromia Both 160 1634 13 dermatologic firebrick 1634, 160 409, 38 408, 48 408, 40 409, 34 -0.00312 0.0915 0.973 0.012 0.997 0.833 1.19 0.242 0.225 0.283 0.548 1.27 0.819 1.98 0.0449 0.233 0.847 0.07199 1.05 0.662 1.65 -0.121 0.242 0.616 0.2102 0.886 0.551 1.42 PRS_PLINK_0.001 FALSE 694.3 Vascular disorders of skin Both 24 228 13 dermatologic firebrick 228, 24 57, 4 57, 8 57, 10 57, 2 -0.341 0.703 0.628 0.2023 0.711 0.179 2.82 0.72 0.596 0.227 0.6435 2.05 0.639 6.61 0.916 0.58 0.114 0.9425 2.5 0.802 7.78 -0.653 0.737 0.376 0.4249 0.521 0.123 2.21 PRS_PLINK_0.001 TRUE 695 Erythematous conditions Both 452 5069 13 dermatologic firebrick 5069, 452 1267, 108 1267, 109 1267, 121 1267, 114 -0.0242 0.0639 0.705 0.152 0.976 0.861 1.11 0.00167 0.141 0.991 0.004138 1 0.76 1.32 0.116 0.138 0.401 0.3974 1.12 0.857 1.47 0.0286 0.14 0.838 0.07683 1.03 0.783 1.35 PRS_PLINK_0.001 FALSE 695.1 Toxic erythema Both 19 225 13 dermatologic firebrick 225, 19 57, 5 56, 4 56, 5 56, 5 0.0274 0.0936 0.77 0.1137 1.03 0.856 1.23 -0.237 0.616 0.7 0.1549 0.789 0.236 2.64 -0.0269 0.602 0.964 0.01576 0.973 0.299 3.17 -0.345 0.614 0.574 0.2411 0.708 0.213 2.36 PRS_PLINK_0.001 TRUE 695.2 Bullous dermatoses Both 23 278 13 dermatologic firebrick 278, 23 70, 5 69, 4 69, 7 70, 7 0.067 0.121 0.579 0.2376 1.07 0.844 1.35 -0.106 0.658 0.872 0.05944 0.899 0.248 3.27 0.333 0.621 0.592 0.2278 1.4 0.413 4.72 0.298 0.556 0.591 0.2281 1.35 0.453 4.01 PRS_PLINK_0.001 TRUE 695.21 Dermatitis herpetiformis Both 5 115 13 dermatologic firebrick 115, 5 29, 0 29, 1 28, 3 29, 1 1.69 1.48 0.256 0.5922 5.4 0.295 98.9 0.845 1.21 0.485 0.3139 2.33 0.217 25 1.22 1.28 0.341 0.4672 3.39 0.275 41.8 0.686 1.09 0.528 0.2777 1.98 0.237 16.7 PRS_PLINK_0.001 TRUE 695.22 Pemphigus and pemphigoid Both 15 153 13 dermatologic firebrick 153, 15 39, 5 38, 3 38, 2 38, 5 0.0374 0.128 0.769 0.1138 1.04 0.808 1.33 -0.374 0.742 0.614 0.2117 0.688 0.161 2.95 -0.616 0.883 0.485 0.314 0.54 0.0958 3.05 0.36 0.692 0.603 0.2196 1.43 0.369 5.56 PRS_PLINK_0.001 TRUE 695.3 Rosacea Both 60 637 13 dermatologic firebrick 637, 60 160, 19 159, 18 159, 7 159, 16 -0.401 0.449 0.372 0.4289 0.67 0.278 1.62 -0.0732 0.338 0.829 0.08164 0.929 0.479 1.8 -0.981 0.43 0.0224 1.65 0.375 0.162 0.87 -0.205 0.349 0.558 0.2533 0.815 0.411 1.62 PRS_PLINK_0.001 FALSE 695.4 Lupus (localized and systemic) Both 85 899 13 dermatologic firebrick 899, 85 225, 14 225, 18 224, 33 225, 20 0.0898 0.108 0.404 0.3931 1.09 0.886 1.35 0.198 0.357 0.578 0.2379 1.22 0.606 2.45 0.894 0.326 0.00602 2.22 2.45 1.29 4.63 0.314 0.346 0.365 0.438 1.37 0.694 2.7 PRS_PLINK_0.001 FALSE 695.41 Cutaneous lupus erythematosus Both 28 279 13 dermatologic firebrick 279, 28 70, 6 70, 6 69, 11 70, 5 0.0616 0.116 0.595 0.2258 1.06 0.848 1.33 0.0217 0.557 0.969 0.01373 1.02 0.343 3.05 0.607 0.515 0.238 0.6225 1.83 0.669 5.03 -0.197 0.577 0.733 0.1352 0.821 0.265 2.54 PRS_PLINK_0.001 TRUE 695.42 Systemic lupus erythematosus Both 72 744 13 dermatologic firebrick 744, 72 186, 14 186, 13 186, 27 186, 18 0.472 0.411 0.25 0.6021 1.6 0.717 3.59 -0.264 0.39 0.499 0.3021 0.768 0.358 1.65 0.641 0.337 0.0571 1.244 1.9 0.981 3.67 0.229 0.355 0.519 0.285 1.26 0.627 2.52 PRS_PLINK_0.001 FALSE 695.7 Prurigo and Lichen Both 154 1637 13 dermatologic firebrick 1637, 154 409, 36 409, 38 409, 40 409, 40 0.0377 0.0903 0.676 0.1699 1.04 0.87 1.24 0.0171 0.241 0.943 0.02526 1.02 0.635 1.63 0.0651 0.237 0.784 0.1059 1.07 0.671 1.7 0.0636 0.237 0.789 0.103 1.07 0.669 1.7 PRS_PLINK_0.001 FALSE 695.8 Other specified erythematous conditions Both 38 524 13 dermatologic firebrick 524, 38 131, 4 131, 9 131, 14 131, 11 0.0137 0.074 0.854 0.06872 1.01 0.877 1.17 0.615 0.548 0.262 0.582 1.85 0.632 5.41 1.15 0.535 0.0316 1.501 3.16 1.11 9 0.881 0.545 0.106 0.9744 2.41 0.829 7.02 PRS_PLINK_0.001 TRUE 695.81 Erythema nodosum Both 13 167 13 dermatologic firebrick 167, 13 42, 2 42, 5 41, 1 42, 5 0.0301 0.101 0.765 0.1165 1.03 0.846 1.25 0.627 0.755 0.406 0.3909 1.87 0.426 8.23 -0.516 0.874 0.555 0.2558 0.597 0.108 3.31 0.569 0.737 0.44 0.3568 1.77 0.417 7.49 PRS_PLINK_0.001 TRUE 695.9 Unspecified erythematous condition Both 85 1006 13 dermatologic firebrick 1006, 85 252, 23 251, 22 251, 23 252, 17 -0.458 0.367 0.212 0.6729 0.633 0.308 1.3 -0.0655 0.304 0.829 0.08123 0.937 0.516 1.7 -0.0145 0.3 0.961 0.01713 0.986 0.548 1.77 -0.332 0.324 0.305 0.5163 0.717 0.381 1.35 PRS_PLINK_0.001 FALSE 696 Psoriasis and related disorders Both 387 4842 13 dermatologic firebrick 4842, 387 1211, 97 1210, 97 1210, 96 1211, 97 -0.00141 0.0562 0.98 0.008798 0.999 0.894 1.11 -0.00426 0.148 0.977 0.01006 0.996 0.744 1.33 -0.0182 0.149 0.903 0.04442 0.982 0.733 1.31 -0.00306 0.148 0.984 0.007217 0.997 0.745 1.33 PRS_PLINK_0.001 FALSE 696.4 Psoriasis Both 377 4736 13 dermatologic firebrick 4736, 377 1184, 93 1184, 96 1184, 94 1184, 94 -0.000607 0.0559 0.991 0.003776 0.999 0.896 1.12 0.0253 0.15 0.866 0.06245 1.03 0.764 1.38 -0.000839 0.151 0.996 0.001928 0.999 0.743 1.34 0.0084 0.151 0.956 0.01972 1.01 0.75 1.36 PRS_PLINK_0.001 FALSE 696.41 Psoriasis vulgaris Both 272 3635 13 dermatologic firebrick 3635, 272 909, 71 909, 75 908, 60 909, 66 -0.00621 0.0658 0.925 0.03396 0.994 0.874 1.13 0.0501 0.171 0.769 0.1139 1.05 0.752 1.47 -0.165 0.18 0.358 0.4458 0.848 0.596 1.21 -0.0697 0.176 0.692 0.16 0.933 0.661 1.32 PRS_PLINK_0.001 FALSE 696.42 Psoriatic arthropathy Both 128 1539 13 dermatologic firebrick 1539, 128 385, 29 385, 28 384, 36 385, 35 0.017 0.0697 0.807 0.09304 1.02 0.887 1.17 -0.0492 0.268 0.854 0.06855 0.952 0.563 1.61 0.243 0.256 0.343 0.4648 1.28 0.772 2.11 0.221 0.257 0.39 0.4088 1.25 0.754 2.06 PRS_PLINK_0.001 FALSE 697 Sarcoidosis Both 104 1190 13 dermatologic firebrick 1190, 104 298, 22 297, 30 297, 24 298, 28 0.00734 0.0862 0.932 0.03051 1.01 0.851 1.19 0.256 0.287 0.372 0.4297 1.29 0.736 2.27 0.114 0.299 0.704 0.1527 1.12 0.624 2.01 0.229 0.288 0.428 0.3687 1.26 0.714 2.21 PRS_PLINK_0.001 FALSE 698 Pruritus and related conditions Both 143 1678 13 dermatologic firebrick 1678, 143 420, 30 419, 26 419, 44 420, 43 0.0647 0.0831 0.436 0.3606 1.07 0.907 1.26 -0.118 0.27 0.663 0.1787 0.889 0.523 1.51 0.411 0.243 0.091 1.041 1.51 0.936 2.43 0.37 0.244 0.129 0.889 1.45 0.898 2.33 PRS_PLINK_0.001 FALSE 700 Corns and callosities Both 51 620 13 dermatologic firebrick 620, 51 155, 8 155, 17 155, 12 155, 14 0.0673 0.112 0.547 0.262 1.07 0.859 1.33 0.692 0.426 0.104 0.9814 2 0.867 4.61 0.377 0.45 0.402 0.3958 1.46 0.604 3.52 0.536 0.432 0.214 0.6697 1.71 0.734 3.98 PRS_PLINK_0.001 FALSE 701 Other hypertrophic and atrophic conditions of skin Both 870 9921 13 dermatologic firebrick 9921, 870 2481, 235 2480, 213 2480, 214 2480, 208 0.0204 0.0269 0.448 0.349 1.02 0.968 1.08 -0.0923 0.0986 0.349 0.4571 0.912 0.752 1.11 -0.0879 0.0984 0.372 0.4299 0.916 0.755 1.11 -0.119 0.099 0.228 0.6422 0.887 0.731 1.08 PRS_PLINK_0.001 FALSE 701.1 Keratoderma, acquired Both 20 189 13 dermatologic firebrick 189, 20 48, 8 47, 6 47, 4 47, 2 -1.02 0.756 0.179 0.7474 0.362 0.0823 1.59 -0.216 0.557 0.698 0.1562 0.806 0.27 2.4 -0.598 0.585 0.306 0.514 0.55 0.175 1.73 -1.15 0.702 0.102 0.9901 0.317 0.0801 1.26 PRS_PLINK_0.001 TRUE 701.2 Scar conditions and fibrosis of skin Both 440 5052 13 dermatologic firebrick 5052, 440 1263, 124 1263, 112 1263, 109 1263, 95 -0.014 0.0502 0.781 0.1076 0.986 0.894 1.09 -0.0941 0.136 0.488 0.3118 0.91 0.698 1.19 -0.13 0.136 0.339 0.4697 0.878 0.672 1.15 -0.271 0.141 0.0551 1.259 0.763 0.578 1.01 PRS_PLINK_0.001 FALSE 701.3 Circumscribed scleroderma Both 9 126 13 dermatologic firebrick 126, 9 32, 1 31, 1 31, 5 32, 2 1.03 1.06 0.332 0.4784 2.8 0.349 22.4 0.0695 1.03 0.946 0.02406 1.07 0.143 8.05 1.33 0.926 0.152 0.8181 3.77 0.613 23.2 0.686 0.969 0.479 0.3193 1.98 0.297 13.3 PRS_PLINK_0.001 TRUE 701.4 Keloid scar Both 33 480 13 dermatologic firebrick 480, 33 120, 8 120, 6 120, 14 120, 5 0.0751 0.556 0.892 0.04942 1.08 0.363 3.2 -0.409 0.52 0.432 0.3643 0.665 0.24 1.84 0.527 0.437 0.228 0.6414 1.69 0.719 3.99 -0.471 0.537 0.38 0.4202 0.624 0.218 1.79 PRS_PLINK_0.001 TRUE 701.5 Abnormal granulation tissue Both 88 955 13 dermatologic firebrick 955, 88 239, 26 239, 18 238, 18 239, 26 0.0588 0.0591 0.32 0.4951 1.06 0.945 1.19 -0.349 0.312 0.262 0.5811 0.705 0.383 1.3 -0.278 0.312 0.373 0.428 0.757 0.41 1.4 -0.0103 0.288 0.971 0.01263 0.99 0.563 1.74 PRS_PLINK_0.001 FALSE 701.6 Acquired acanthosis nigricans Both 22 201 13 dermatologic firebrick 201, 22 51, 8 50, 6 50, 3 50, 5 0.0869 0.0565 0.124 0.9067 1.09 0.976 1.22 -0.279 0.594 0.638 0.1949 0.756 0.236 2.42 -0.651 0.644 0.312 0.5057 0.522 0.148 1.84 -0.312 0.574 0.587 0.2311 0.732 0.238 2.26 PRS_PLINK_0.001 TRUE 702 Degenerative skin conditions and other dermatoses Both 1106 11285 13 dermatologic firebrick 11285, 1106 2822, 283 2821, 290 2821, 266 2821, 267 -0.00771 0.0307 0.802 0.09605 0.992 0.934 1.05 0.0216 0.0875 0.805 0.09433 1.02 0.861 1.21 -0.0634 0.0893 0.478 0.3208 0.939 0.788 1.12 -0.0538 0.0893 0.547 0.2619 0.948 0.796 1.13 PRS_PLINK_0.001 FALSE 702.1 Actinic keratosis Both 515 5172 13 dermatologic firebrick 5172, 515 1293, 132 1293, 134 1293, 124 1293, 125 0.0456 0.0333 0.171 0.768 1.05 0.981 1.12 0.0114 0.128 0.929 0.03193 1.01 0.787 1.3 -0.0653 0.131 0.617 0.2095 0.937 0.725 1.21 -0.0558 0.13 0.668 0.175 0.946 0.732 1.22 PRS_PLINK_0.001 FALSE 702.2 Seborrheic keratosis Both 618 6465 13 dermatologic firebrick 6465, 618 1617, 155 1616, 162 1616, 155 1616, 146 -0.125 0.0892 0.161 0.7931 0.882 0.741 1.05 0.0416 0.117 0.723 0.1408 1.04 0.828 1.31 0.00423 0.118 0.972 0.01253 1 0.796 1.27 -0.0597 0.12 0.62 0.2079 0.942 0.744 1.19 PRS_PLINK_0.001 FALSE 703 Diseases of nail, NOS Both 51 729 13 dermatologic firebrick 729, 51 183, 13 182, 14 182, 6 182, 18 0.0629 0.0853 0.461 0.3365 1.06 0.901 1.26 0.172 0.39 0.659 0.1808 1.19 0.553 2.55 -0.582 0.47 0.216 0.6655 0.559 0.222 1.4 0.299 0.372 0.421 0.3762 1.35 0.651 2.79 PRS_PLINK_0.001 FALSE 703.1 Ingrowing nail Both 138 2058 13 dermatologic firebrick 2058, 138 515, 34 514, 34 514, 31 515, 39 0.00469 0.067 0.944 0.02494 1 0.881 1.15 -0.0061 0.245 0.98 0.008703 0.994 0.615 1.61 -0.0963 0.25 0.7 0.1549 0.908 0.556 1.48 0.156 0.239 0.513 0.2897 1.17 0.732 1.87 PRS_PLINK_0.001 FALSE 704 Diseases of hair and hair follicles Both 1103 11367 13 dermatologic firebrick 11367, 1103 2842, 262 2842, 263 2841, 286 2842, 292 0.015 0.025 0.548 0.2613 1.02 0.967 1.07 0.00161 0.091 0.986 0.00619 1 0.838 1.2 0.0831 0.0894 0.353 0.4526 1.09 0.912 1.29 0.108 0.089 0.227 0.6446 1.11 0.935 1.33 PRS_PLINK_0.001 FALSE 704.1 Alopecia Both 26 261 13 dermatologic firebrick 261, 26 66, 11 65, 3 65, 5 65, 7 -1.01 0.699 0.147 0.8341 0.363 0.0922 1.43 -1.15 0.62 0.0645 1.191 0.318 0.0943 1.07 -0.528 0.555 0.341 0.4672 0.59 0.199 1.75 -0.768 0.546 0.16 0.797 0.464 0.159 1.35 PRS_PLINK_0.001 TRUE 704.8 Other specified diseases of hair and hair follicles Both 20 157 13 dermatologic firebrick 157, 20 40, 4 39, 7 39, 3 39, 6 0.676 0.778 0.385 0.4148 1.97 0.428 9.04 0.518 0.641 0.42 0.377 1.68 0.477 5.9 -0.362 0.76 0.634 0.1978 0.696 0.157 3.09 PRS_PLINK_0.001 TRUE 705 Disorders of sweat glands Both 35 489 13 dermatologic firebrick 489, 35 123, 9 122, 6 122, 5 122, 15 0.113 0.0578 0.0506 1.296 1.12 1 1.25 -0.435 0.507 0.391 0.4077 0.647 0.24 1.75 -0.427 0.53 0.421 0.3756 0.653 0.231 1.85 0.491 0.424 0.247 0.6079 1.63 0.712 3.75 PRS_PLINK_0.001 TRUE 705.3 Hidradenitis Both 28 414 13 dermatologic firebrick 414, 28 104, 7 103, 6 103, 4 104, 11 0.109 0.0518 0.0353 1.453 1.12 1.01 1.23 -0.206 0.53 0.697 0.1565 0.814 0.288 2.3 -0.555 0.586 0.344 0.463 0.574 0.182 1.81 0.521 0.478 0.276 0.5598 1.68 0.66 4.3 PRS_PLINK_0.001 TRUE 705.8 Hyperhidrosis Both 112 1284 13 dermatologic firebrick 1284, 112 321, 31 321, 29 321, 19 321, 33 0.0069 0.0844 0.935 0.02925 1.01 0.853 1.19 -0.106 0.266 0.691 0.1607 0.899 0.533 1.52 -0.472 0.295 0.11 0.9599 0.624 0.35 1.11 0.0793 0.258 0.759 0.1198 1.08 0.652 1.8 PRS_PLINK_0.001 FALSE 706 Diseases of sebaceous glands Both 1694 17847 13 dermatologic firebrick 17847, 1694 4462, 386 4462, 419 4461, 447 4462, 442 0.00288 0.0231 0.901 0.04542 1 0.959 1.05 0.0818 0.0735 0.266 0.5755 1.09 0.94 1.25 0.146 0.0725 0.0438 1.358 1.16 1 1.33 0.135 0.0727 0.064 1.194 1.14 0.992 1.32 PRS_PLINK_0.001 FALSE 706.1 Acne Both 16 167 13 dermatologic firebrick 167, 16 42, 2 42, 5 41, 6 42, 3 -4.66 0.982 2.06e-06 5.686 0.00945 0.00138 0.0647 0.086 0.852 0.92 0.03638 1.09 0.205 5.79 0.657 0.857 0.443 0.3534 1.93 0.36 10.4 0.355 0.795 0.655 0.184 1.43 0.301 6.77 PRS_PLINK_0.001 TRUE 706.2 Sebaceous cyst Both 1748 18712 13 dermatologic firebrick 18712, 1748 4678, 405 4678, 420 4678, 458 4678, 465 0.00299 0.0226 0.895 0.04833 1 0.96 1.05 0.0371 0.0725 0.609 0.2156 1.04 0.9 1.2 0.122 0.0712 0.0867 1.062 1.13 0.983 1.3 0.138 0.071 0.0512 1.29 1.15 0.999 1.32 PRS_PLINK_0.001 FALSE 707 Chronic ulcer of skin Both 264 4114 13 dermatologic firebrick 4114, 264 1029, 70 1028, 68 1028, 67 1029, 59 0.0854 0.0358 0.0169 1.771 1.09 1.02 1.17 -0.026 0.174 0.881 0.05478 0.974 0.692 1.37 -0.0386 0.175 0.825 0.08348 0.962 0.683 1.36 -0.175 0.18 0.33 0.4809 0.839 0.59 1.19 PRS_PLINK_0.001 FALSE 707.1 Decubitus ulcer Both 105 1888 13 dermatologic firebrick 1888, 105 472, 33 472, 30 472, 23 472, 19 -0.893 0.333 0.00727 2.138 0.409 0.213 0.786 -0.124 0.256 0.628 0.2021 0.883 0.534 1.46 -0.341 0.273 0.211 0.6766 0.711 0.416 1.21 -0.523 0.288 0.0692 1.16 0.593 0.337 1.04 PRS_PLINK_0.001 FALSE 709 Diffuse diseases of connective tissue Both 701 7186 13 dermatologic firebrick 7186, 701 1797, 168 1796, 192 1796, 168 1797, 173 0.0101 0.0342 0.768 0.1146 1.01 0.945 1.08 0.135 0.11 0.22 0.6578 1.15 0.922 1.42 0.00327 0.114 0.977 0.01009 1 0.803 1.25 0.0253 0.113 0.823 0.08472 1.03 0.822 1.28 PRS_PLINK_0.001 FALSE 709.2 Sicca syndrome Both 112 1048 13 dermatologic firebrick 1048, 112 262, 29 262, 27 262, 27 262, 29 0.000116 0.0878 0.999 0.0004572 1 0.842 1.19 -0.0589 0.277 0.832 0.08014 0.943 0.548 1.62 -0.0683 0.276 0.805 0.0944 0.934 0.544 1.6 -0.0325 0.272 0.905 0.04339 0.968 0.568 1.65 PRS_PLINK_0.001 FALSE 709.3 Systemic sclerosis Both 39 353 13 dermatologic firebrick 353, 39 89, 7 88, 13 88, 11 88, 8 0.291 0.558 0.602 0.2206 1.34 0.448 3.99 0.532 0.473 0.261 0.5841 1.7 0.674 4.3 0.389 0.489 0.427 0.3699 1.48 0.566 3.85 0.0889 0.506 0.861 0.06524 1.09 0.406 2.95 PRS_PLINK_0.001 TRUE 709.6 Other specified diffuse diseases of connective tissue Both 12 141 13 dermatologic firebrick 141, 12 36, 2 35, 6 35, 4 35, 0 -1.05 0.922 0.257 0.5902 0.352 0.0577 2.14 0.863 0.739 0.243 0.6148 2.37 0.557 10.1 0.749 0.789 0.343 0.4651 2.11 0.45 9.93 -1.31 1.11 0.235 0.6288 0.269 0.0307 2.35 PRS_PLINK_0.001 TRUE 709.7 Unspecified diffuse connective tissue disease Both 542 5656 13 dermatologic firebrick 5656, 542 1414, 126 1414, 152 1414, 126 1414, 138 0.0197 0.0344 0.567 0.2465 1.02 0.953 1.09 0.19 0.126 0.13 0.885 1.21 0.945 1.55 0.000976 0.131 0.994 0.002592 1 0.775 1.29 0.0878 0.128 0.493 0.3068 1.09 0.849 1.4 PRS_PLINK_0.001 FALSE 710 Osteomyelitis, periostitis, and other infections involving bone Both 93 1349 14 musculoskeletal darkolivegreen 1349, 93 338, 26 337, 21 337, 27 337, 19 0.0622 0.0499 0.212 0.6738 1.06 0.965 1.17 -0.195 0.294 0.507 0.2954 0.822 0.462 1.46 0.0371 0.278 0.894 0.0487 1.04 0.601 1.79 -0.316 0.301 0.295 0.5307 0.729 0.404 1.32 PRS_PLINK_0.001 FALSE 710.1 Osteomyelitis Both 80 1265 14 musculoskeletal darkolivegreen 1265, 80 317, 24 316, 17 316, 23 316, 16 0.0741 0.0528 0.161 0.7935 1.08 0.971 1.19 -0.317 0.316 0.316 0.5003 0.728 0.392 1.35 -0.0439 0.294 0.881 0.05489 0.957 0.538 1.7 -0.4 0.32 0.212 0.6729 0.671 0.358 1.26 PRS_PLINK_0.001 FALSE 710.12 Chronic osteomyelitis Both 34 455 14 musculoskeletal darkolivegreen 455, 34 114, 7 114, 9 113, 8 114, 10 0.0174 0.587 0.976 0.01041 1.02 0.322 3.22 0.27 0.515 0.601 0.2213 1.31 0.477 3.59 0.224 0.506 0.658 0.1815 1.25 0.464 3.37 0.444 0.485 0.361 0.4427 1.56 0.602 4.03 PRS_PLINK_0.001 TRUE 710.19 Unspecified osteomyelitis Both 54 876 14 musculoskeletal darkolivegreen 876, 54 219, 17 219, 11 219, 16 219, 10 0.0654 0.0526 0.213 0.6714 1.07 0.963 1.18 -0.383 0.38 0.313 0.5047 0.682 0.324 1.44 -0.104 0.346 0.764 0.1168 0.901 0.457 1.78 -0.569 0.392 0.147 0.8335 0.566 0.262 1.22 PRS_PLINK_0.001 FALSE 711 Arthropathy associated with infections Both 64 935 14 musculoskeletal darkolivegreen 935, 64 234, 11 234, 20 233, 16 234, 17 0.0618 0.0914 0.499 0.3018 1.06 0.889 1.27 0.562 0.373 0.132 0.8803 1.75 0.845 3.64 0.379 0.38 0.318 0.4974 1.46 0.694 3.08 0.439 0.386 0.255 0.5938 1.55 0.728 3.3 PRS_PLINK_0.001 FALSE 711.1 Pyogenic arthritis Both 47 719 14 musculoskeletal darkolivegreen 719, 47 180, 7 180, 16 179, 11 180, 13 0.068 0.0926 0.463 0.3347 1.07 0.893 1.28 0.775 0.437 0.0761 1.119 2.17 0.922 5.11 0.467 0.454 0.304 0.5176 1.59 0.655 3.88 0.622 0.455 0.172 0.7644 1.86 0.763 4.55 PRS_PLINK_0.001 TRUE 712 Infective connective tissue disorders Both 15 178 14 musculoskeletal darkolivegreen 178, 15 45, 4 44, 8 44, 2 45, 1 -1.28 0.855 0.134 0.8731 0.277 0.0519 1.48 0.681 0.618 0.271 0.5678 1.97 0.589 6.63 -0.198 0.762 0.795 0.09974 0.82 0.184 3.65 -1.51 0.986 0.125 0.9028 0.22 0.0319 1.52 PRS_PLINK_0.001 TRUE 713 Arthropathy associated with other disorders classified elsewhere Both 14 310 14 musculoskeletal darkolivegreen 310, 14 78, 3 77, 4 77, 2 78, 5 0.275 0.786 0.727 0.1386 1.32 0.282 6.14 -0.0802 0.721 0.911 0.04025 0.923 0.224 3.79 -0.533 0.757 0.481 0.3176 0.587 0.133 2.59 0.204 0.662 0.758 0.1205 1.23 0.335 4.49 PRS_PLINK_0.001 TRUE 713.5 Arthropathy associated with neurological disorders Both 3 137 14 musculoskeletal darkolivegreen 137, 3 35, 0 34, 0 34, 0 34, 3 2.46 1.15 0.0321 1.494 11.8 1.24 112 0.0336 1.17 0.977 0.01009 1.03 0.105 10.2 0.3 1.12 0.789 0.103 1.35 0.15 12.1 1.56 1.17 0.183 0.7377 4.78 0.478 47.7 PRS_PLINK_0.001 TRUE 714 Rheumatoid arthritis and other inflammatory polyarthropathies Both 838 10117 14 musculoskeletal darkolivegreen 10117, 838 2530, 200 2529, 208 2529, 205 2529, 225 0.00881 0.033 0.79 0.1026 1.01 0.946 1.08 0.0391 0.103 0.703 0.1529 1.04 0.85 1.27 0.028 0.103 0.786 0.1047 1.03 0.84 1.26 0.12 0.101 0.233 0.6334 1.13 0.926 1.37 PRS_PLINK_0.001 FALSE 714.1 Rheumatoid arthritis Both 758 9146 14 musculoskeletal darkolivegreen 9146, 758 2287, 175 2286, 193 2286, 182 2287, 208 0.0119 0.033 0.718 0.1439 1.01 0.949 1.08 0.0982 0.108 0.364 0.4393 1.1 0.893 1.36 0.0406 0.11 0.711 0.1482 1.04 0.84 1.29 0.176 0.106 0.0987 1.006 1.19 0.968 1.47 PRS_PLINK_0.001 FALSE 715 Other inflammatory spondylopathies Both 268 3602 14 musculoskeletal darkolivegreen 3602, 268 901, 69 900, 68 900, 68 901, 63 -0.0497 0.077 0.518 0.2853 0.952 0.818 1.11 -0.0174 0.176 0.921 0.03566 0.983 0.696 1.39 -0.00878 0.176 0.96 0.01769 0.991 0.703 1.4 -0.0924 0.179 0.605 0.2184 0.912 0.642 1.29 PRS_PLINK_0.001 FALSE 715.1 Sacroiliitis NEC Both 22 230 14 musculoskeletal darkolivegreen 230, 22 58, 6 57, 3 57, 7 58, 6 0.0358 0.121 0.768 0.1148 1.04 0.817 1.31 -0.464 0.656 0.48 0.319 0.629 0.174 2.28 0.109 0.556 0.844 0.07341 1.12 0.375 3.32 -0.427 0.617 0.489 0.3107 0.653 0.195 2.19 PRS_PLINK_0.001 TRUE 715.2 Ankylosing spondylitis Both 121 1357 14 musculoskeletal darkolivegreen 1357, 121 340, 32 339, 34 339, 26 339, 29 -7.72e-05 0.0909 0.999 0.0002942 1 0.837 1.19 0.0625 0.254 0.806 0.09387 1.06 0.647 1.75 -0.195 0.269 0.469 0.329 0.823 0.485 1.39 -0.0947 0.263 0.719 0.1433 0.91 0.543 1.52 PRS_PLINK_0.001 FALSE 716 Other arthropathies Both 6549 58058 14 musculoskeletal darkolivegreen 58058, 6549 14514, 1587 14514, 1654 14514, 1579 14515, 1729 0.0114 0.0114 0.314 0.5025 1.01 0.989 1.03 0.0417 0.0372 0.263 0.5805 1.04 0.969 1.12 -0.00578 0.0376 0.878 0.05662 0.994 0.924 1.07 0.0874 0.0368 0.0177 1.753 1.09 1.02 1.17 PRS_PLINK_0.001 FALSE 716.1 Unspecified polyarthropathy or polyarthritis Both 607 7334 14 musculoskeletal darkolivegreen 7334, 607 1834, 143 1833, 165 1833, 144 1834, 155 0.0235 0.0321 0.464 0.3335 1.02 0.961 1.09 0.144 0.118 0.225 0.6482 1.15 0.915 1.46 0.0101 0.122 0.934 0.02964 1.01 0.795 1.28 0.0752 0.12 0.532 0.2744 1.08 0.852 1.36 PRS_PLINK_0.001 FALSE 716.2 Unspecified monoarthritis Both 2802 33071 14 musculoskeletal darkolivegreen 33071, 2802 8268, 695 8268, 691 8267, 681 8268, 735 0.0138 0.0173 0.424 0.3727 1.01 0.98 1.05 -0.00768 0.0559 0.891 0.0503 0.992 0.889 1.11 -0.021 0.0561 0.708 0.1503 0.979 0.877 1.09 0.0563 0.0551 0.307 0.5134 1.06 0.95 1.18 PRS_PLINK_0.001 FALSE 716.9 Arthropathy NOS Both 6249 57343 14 musculoskeletal darkolivegreen 57343, 6249 14335, 1513 14336, 1583 14335, 1496 14336, 1657 0.00965 0.0119 0.416 0.3811 1.01 0.987 1.03 0.0457 0.038 0.229 0.6406 1.05 0.972 1.13 -0.0117 0.0385 0.761 0.1184 0.988 0.917 1.07 0.0924 0.0376 0.0139 1.858 1.1 1.02 1.18 PRS_PLINK_0.001 FALSE 717 Polymyalgia Rheumatica Both 199 2260 14 musculoskeletal darkolivegreen 2260, 199 564, 63 565, 55 565, 42 565, 39 -0.477 0.236 0.0433 1.364 0.62 0.391 0.986 -0.141 0.192 0.462 0.3356 0.868 0.596 1.26 -0.397 0.206 0.0539 1.268 0.672 0.449 1.01 -0.48 0.21 0.0222 1.653 0.618 0.41 0.934 PRS_PLINK_0.001 FALSE 720 Spinal stenosis Both 594 7632 14 musculoskeletal darkolivegreen 7632, 594 1908, 139 1908, 150 1908, 144 1908, 161 0.0111 0.0388 0.775 0.1109 1.01 0.937 1.09 0.0824 0.122 0.498 0.3026 1.09 0.856 1.38 0.0399 0.123 0.745 0.128 1.04 0.818 1.32 0.143 0.12 0.234 0.6316 1.15 0.912 1.46 PRS_PLINK_0.001 FALSE 721 Spondylosis and allied disorders Both 1224 16285 14 musculoskeletal darkolivegreen 16285, 1224 4072, 281 4071, 336 4071, 293 4071, 314 -0.00797 0.0294 0.786 0.1045 0.992 0.937 1.05 0.177 0.0836 0.0342 1.466 1.19 1.01 1.41 0.0406 0.0862 0.637 0.1957 1.04 0.88 1.23 0.113 0.0848 0.183 0.7365 1.12 0.948 1.32 PRS_PLINK_0.001 FALSE 721.1 Spondylosis without myelopathy Both 777 10403 14 musculoskeletal darkolivegreen 10403, 777 2601, 169 2601, 208 2600, 206 2601, 194 -0.00242 0.0364 0.947 0.02359 0.998 0.929 1.07 0.204 0.107 0.0563 1.25 1.23 0.995 1.51 0.197 0.107 0.0662 1.179 1.22 0.987 1.5 0.139 0.108 0.201 0.6974 1.15 0.929 1.42 PRS_PLINK_0.001 FALSE 721.2 Spondylosis with myelopathy Both 26 415 14 musculoskeletal darkolivegreen 415, 26 104, 5 104, 8 103, 3 104, 10 0.229 0.122 0.0608 1.216 1.26 0.99 1.6 0.352 0.548 0.52 0.2839 1.42 0.486 4.16 -0.31 0.648 0.632 0.1991 0.733 0.206 2.61 0.827 0.533 0.121 0.9163 2.29 0.803 6.5 PRS_PLINK_0.001 TRUE 721.8 Other allied disorders of spine Both 57 727 14 musculoskeletal darkolivegreen 727, 57 182, 12 182, 15 181, 8 182, 22 0.076 0.0902 0.4 0.3981 1.08 0.904 1.29 0.16 0.381 0.676 0.1702 1.17 0.555 2.48 -0.354 0.437 0.418 0.3789 0.702 0.298 1.65 0.619 0.362 0.0872 1.059 1.86 0.914 3.78 PRS_PLINK_0.001 FALSE 722 Intervertebral disc disorders Both 1594 19316 14 musculoskeletal darkolivegreen 19316, 1594 4829, 364 4829, 412 4829, 417 4829, 401 0.0208 0.0223 0.351 0.4549 1.02 0.977 1.07 0.122 0.0746 0.102 0.9934 1.13 0.976 1.31 0.132 0.0745 0.0766 1.116 1.14 0.986 1.32 0.0933 0.0751 0.214 0.6692 1.1 0.948 1.27 PRS_PLINK_0.001 FALSE 722.1 Displacement of intervertebral disc Both 79 1101 14 musculoskeletal darkolivegreen 1101, 79 276, 25 275, 15 275, 22 275, 17 0.0651 0.0497 0.19 0.7212 1.07 0.968 1.18 -0.552 0.327 0.0919 1.037 0.576 0.303 1.09 -0.13 0.299 0.664 0.1775 0.878 0.489 1.58 -0.386 0.317 0.223 0.6519 0.68 0.365 1.26 PRS_PLINK_0.001 FALSE 722.6 Degeneration of intervertebral disc Both 487 5974 14 musculoskeletal darkolivegreen 5974, 487 1494, 101 1493, 140 1493, 118 1494, 128 0.00443 0.0523 0.933 0.03032 1 0.907 1.11 0.324 0.135 0.0163 1.788 1.38 1.06 1.8 0.152 0.14 0.278 0.5563 1.16 0.885 1.53 0.224 0.137 0.104 0.9831 1.25 0.955 1.64 PRS_PLINK_0.001 FALSE 722.8 Postlaminectomy syndrome Both 12 146 14 musculoskeletal darkolivegreen 146, 12 37, 2 36, 2 36, 3 37, 5 -0.757 0.958 0.429 0.3672 0.469 0.0717 3.07 0.299 0.787 0.704 0.1523 1.35 0.288 6.3 1.01 0.777 0.195 0.7099 2.74 0.597 12.5 PRS_PLINK_0.001 TRUE 722.9 Other and unspecified disc disorder Both 772 9562 14 musculoskeletal darkolivegreen 9562, 772 2391, 188 2390, 189 2390, 204 2391, 191 0.0294 0.0277 0.288 0.5401 1.03 0.975 1.09 0.0081 0.107 0.939 0.02714 1.01 0.818 1.24 0.0826 0.105 0.431 0.3655 1.09 0.884 1.33 0.0139 0.106 0.896 0.0477 1.01 0.823 1.25 PRS_PLINK_0.001 FALSE 723 Other disorders of cervical region Both 85 1115 14 musculoskeletal darkolivegreen 1115, 85 279, 20 279, 32 278, 14 279, 19 -0.366 0.368 0.32 0.4948 0.694 0.338 1.43 0.477 0.29 0.1 0.9989 1.61 0.912 2.84 -0.326 0.342 0.34 0.4685 0.722 0.369 1.41 -0.0559 0.321 0.862 0.06458 0.946 0.504 1.77 PRS_PLINK_0.001 FALSE 723.1 Torticollis Both 23 234 14 musculoskeletal darkolivegreen 234, 23 59, 2 58, 11 58, 3 59, 7 0.51 0.763 0.504 0.2974 1.67 0.373 7.43 1.59 0.71 0.0249 1.604 4.92 1.22 19.8 0.427 0.737 0.562 0.2499 1.53 0.362 6.49 1.2 0.739 0.105 0.9789 3.32 0.778 14.1 PRS_PLINK_0.001 TRUE 724 Other and unspecified disorders of back Both 343 4381 14 musculoskeletal darkolivegreen 4381, 343 1096, 93 1095, 88 1095, 78 1095, 84 -0.0405 0.0774 0.6 0.2216 0.96 0.825 1.12 -0.0568 0.153 0.711 0.1479 0.945 0.699 1.28 -0.19 0.159 0.232 0.6354 0.827 0.606 1.13 -0.0929 0.155 0.55 0.2597 0.911 0.672 1.24 PRS_PLINK_0.001 FALSE 724.1 Disorders of sacrum Both 80 885 14 musculoskeletal darkolivegreen 885, 80 222, 20 221, 22 221, 18 221, 20 0.0547 0.124 0.66 0.1804 1.06 0.828 1.35 0.0144 0.319 0.964 0.01589 1.01 0.543 1.89 -0.169 0.332 0.612 0.2136 0.845 0.44 1.62 -0.0274 0.323 0.932 0.03038 0.973 0.517 1.83 PRS_PLINK_0.001 FALSE 724.2 Disorders of coccyx Both 81 890 14 musculoskeletal darkolivegreen 890, 81 223, 19 222, 24 222, 18 223, 20 0.0547 0.126 0.663 0.1785 1.06 0.826 1.35 0.133 0.317 0.675 0.1708 1.14 0.614 2.12 -0.0621 0.335 0.853 0.06898 0.94 0.487 1.81 0.0494 0.326 0.88 0.05561 1.05 0.554 1.99 PRS_PLINK_0.001 FALSE 724.8 Other symptoms referable to back Both 18 128 14 musculoskeletal darkolivegreen 128, 18 32, 3 32, 5 32, 6 32, 4 0.538 0.831 0.517 0.2863 1.71 0.336 8.73 0.494 0.692 0.475 0.3235 1.64 0.423 6.36 0.481 0.716 0.501 0.3 1.62 0.398 6.58 0.26 0.744 0.727 0.1385 1.3 0.302 5.57 PRS_PLINK_0.001 TRUE 724.9 Other unspecified back disorders Both 247 3418 14 musculoskeletal darkolivegreen 3418, 247 855, 70 854, 61 854, 57 855, 59 -0.031 0.0748 0.679 0.1683 0.969 0.837 1.12 -0.133 0.18 0.459 0.338 0.876 0.616 1.24 -0.206 0.183 0.262 0.5825 0.814 0.568 1.17 -0.15 0.181 0.408 0.3895 0.861 0.603 1.23 PRS_PLINK_0.001 FALSE 726 Peripheral enthesopathies and allied syndromes Both 2714 31697 14 musculoskeletal darkolivegreen 31697, 2714 7925, 670 7924, 686 7924, 669 7924, 689 0.0124 0.0172 0.47 0.3276 1.01 0.979 1.05 0.0227 0.0565 0.688 0.1624 1.02 0.916 1.14 0.00112 0.0569 0.984 0.006854 1 0.896 1.12 0.0292 0.0565 0.606 0.2177 1.03 0.922 1.15 PRS_PLINK_0.001 FALSE 726.1 Enthesopathy Both 1744 20467 14 musculoskeletal darkolivegreen 20467, 1744 5117, 430 5117, 441 5116, 430 5117, 443 -0.00767 0.0249 0.758 0.1202 0.992 0.945 1.04 0.024 0.0705 0.733 0.1349 1.02 0.892 1.18 0.0027 0.0709 0.97 0.01338 1 0.873 1.15 0.0314 0.0704 0.656 0.1832 1.03 0.899 1.18 PRS_PLINK_0.001 FALSE 726.2 Synoviopathy Both 67 758 14 musculoskeletal darkolivegreen 758, 67 190, 14 189, 10 189, 21 190, 22 0.0595 0.0889 0.504 0.2978 1.06 0.892 1.26 -0.35 0.408 0.391 0.4076 0.705 0.317 1.57 0.415 0.351 0.237 0.6258 1.51 0.762 3.01 0.461 0.35 0.188 0.727 1.59 0.799 3.15 PRS_PLINK_0.001 FALSE 726.3 Bursitis Both 142 1862 14 musculoskeletal darkolivegreen 1862, 142 466, 40 465, 39 465, 36 466, 27 -0.461 0.283 0.103 0.9853 0.63 0.362 1.1 -0.0173 0.231 0.94 0.02671 0.983 0.625 1.55 -0.115 0.234 0.623 0.2056 0.891 0.563 1.41 -0.395 0.253 0.118 0.9284 0.673 0.41 1.11 PRS_PLINK_0.001 FALSE 727 Other disorders of synovium, tendon, and bursa Both 1454 15759 14 musculoskeletal darkolivegreen 15759, 1454 3940, 344 3940, 357 3939, 377 3940, 376 0.0232 0.0221 0.293 0.533 1.02 0.98 1.07 0.0375 0.0787 0.634 0.198 1.04 0.89 1.21 0.0911 0.0777 0.241 0.6173 1.1 0.941 1.28 0.0889 0.0778 0.253 0.597 1.09 0.938 1.27 PRS_PLINK_0.001 FALSE 727.1 Synovitis and tenosynovitis Both 534 5809 14 musculoskeletal darkolivegreen 5809, 534 1453, 141 1452, 126 1452, 125 1452, 142 0.021 0.0337 0.533 0.2729 1.02 0.956 1.09 -0.114 0.128 0.371 0.4307 0.892 0.695 1.15 -0.121 0.128 0.345 0.462 0.886 0.69 1.14 0.00873 0.124 0.944 0.02509 1.01 0.791 1.29 PRS_PLINK_0.001 FALSE 727.2 Bursitis disorders Both 23 234 14 musculoskeletal darkolivegreen 234, 23 59, 3 58, 5 58, 7 59, 8 0.864 0.755 0.252 0.5984 2.37 0.541 10.4 0.609 0.655 0.352 0.4534 1.84 0.51 6.63 0.732 0.631 0.246 0.6098 2.08 0.604 7.16 0.79 0.657 0.229 0.6401 2.2 0.608 7.99 PRS_PLINK_0.001 TRUE 727.4 Ganglion and cyst of synovium, tendon, and bursa Both 626 6670 14 musculoskeletal darkolivegreen 6670, 626 1668, 152 1667, 152 1667, 166 1668, 156 0.0222 0.0306 0.468 0.3299 1.02 0.963 1.09 0.000581 0.119 0.996 0.00169 1 0.792 1.26 0.0901 0.117 0.441 0.3553 1.09 0.87 1.38 0.0308 0.119 0.795 0.09954 1.03 0.817 1.3 PRS_PLINK_0.001 FALSE 727.5 Rupture of synovium Both 113 1188 14 musculoskeletal darkolivegreen 1188, 113 297, 16 297, 33 297, 35 297, 29 0.0401 0.0843 0.634 0.1979 1.04 0.882 1.23 0.725 0.306 0.0179 1.748 2.07 1.13 3.76 0.808 0.307 0.00851 2.07 2.24 1.23 4.09 0.552 0.316 0.0805 1.094 1.74 0.935 3.23 PRS_PLINK_0.001 FALSE 727.6 Rupture of tendon, nontraumatic Both 72 753 14 musculoskeletal darkolivegreen 753, 72 189, 21 188, 20 188, 13 188, 18 0.0161 0.107 0.881 0.05517 1.02 0.824 1.25 -0.108 0.325 0.739 0.1316 0.897 0.475 1.7 -0.459 0.354 0.195 0.711 0.632 0.316 1.26 -0.221 0.334 0.509 0.2936 0.802 0.417 1.54 PRS_PLINK_0.001 FALSE 727.7 Contracture of tendon (sheath) Both 24 312 14 musculoskeletal darkolivegreen 312, 24 78, 6 78, 8 78, 3 78, 7 -0.294 0.624 0.638 0.195 0.746 0.219 2.54 0.223 0.524 0.67 0.174 1.25 0.448 3.49 -0.546 0.621 0.379 0.4214 0.579 0.172 1.95 0.128 0.54 0.813 0.09013 1.14 0.395 3.27 PRS_PLINK_0.001 TRUE 728 Disorders of muscle, ligament, and fascia Both 676 7672 14 musculoskeletal darkolivegreen 7672, 676 1918, 159 1918, 166 1918, 186 1918, 165 0.0127 0.0364 0.727 0.1385 1.01 0.943 1.09 0.0466 0.115 0.686 0.1636 1.05 0.836 1.31 0.149 0.112 0.185 0.734 1.16 0.931 1.45 0.0249 0.116 0.829 0.08129 1.03 0.818 1.29 PRS_PLINK_0.001 FALSE 728.2 Laxity of ligament or hypermobility syndrome Both 88 932 14 musculoskeletal darkolivegreen 932, 88 233, 23 233, 24 233, 20 233, 21 0.0879 0.0663 0.185 0.7336 1.09 0.959 1.24 0.0265 0.302 0.93 0.03154 1.03 0.568 1.86 -0.16 0.314 0.61 0.2148 0.852 0.46 1.58 -0.143 0.311 0.646 0.1895 0.867 0.471 1.6 PRS_PLINK_0.001 FALSE 728.7 Fasciitis Both 711 8006 14 musculoskeletal darkolivegreen 8006, 711 2002, 171 2001, 182 2001, 187 2002, 171 0.0322 0.0342 0.347 0.4594 1.03 0.966 1.1 0.0642 0.111 0.562 0.2503 1.07 0.858 1.32 0.0857 0.11 0.436 0.3603 1.09 0.878 1.35 -0.0123 0.112 0.913 0.03961 0.988 0.792 1.23 PRS_PLINK_0.001 FALSE 728.71 Contracture of palmar fascia [Dupuytren's disease] Both 645 7261 14 musculoskeletal darkolivegreen 7261, 645 1816, 154 1815, 162 1815, 175 1815, 154 0.0166 0.0392 0.673 0.172 1.02 0.941 1.1 0.051 0.117 0.663 0.1786 1.05 0.837 1.32 0.121 0.115 0.292 0.5345 1.13 0.901 1.41 -0.0133 0.118 0.911 0.04055 0.987 0.782 1.24 PRS_PLINK_0.001 FALSE 729 Other disorders of soft tissues Both 1019 12746 14 musculoskeletal darkolivegreen 12746, 1019 3187, 261 3186, 243 3186, 261 3187, 254 0.0163 0.0266 0.54 0.2679 1.02 0.965 1.07 -0.0702 0.0924 0.447 0.3497 0.932 0.778 1.12 -0.00456 0.0909 0.96 0.01772 0.995 0.833 1.19 -0.0309 0.0914 0.736 0.1332 0.97 0.811 1.16 PRS_PLINK_0.001 FALSE 729.1 Rheumatism, unspecified and fibrositis Both 147 2213 14 musculoskeletal darkolivegreen 2213, 147 554, 33 553, 35 553, 38 553, 41 0.0598 0.0431 0.166 0.7803 1.06 0.976 1.16 0.0475 0.245 0.846 0.07256 1.05 0.649 1.69 0.137 0.241 0.568 0.2456 1.15 0.716 1.84 0.216 0.239 0.366 0.4364 1.24 0.777 1.99 PRS_PLINK_0.001 FALSE 729.3 Panniculitis Both 12 215 14 musculoskeletal darkolivegreen 215, 12 54, 4 54, 3 53, 2 54, 3 0.341 0.811 0.675 0.171 1.41 0.287 6.89 -0.0702 0.708 0.921 0.03573 0.932 0.233 3.74 -0.91 0.85 0.284 0.5462 0.403 0.0761 2.13 -0.189 0.678 0.78 0.108 0.827 0.219 3.12 PRS_PLINK_0.001 TRUE 731 Osteitis deformans and osteopathies associated with other disorders classified elsewhere Both 55 626 14 musculoskeletal darkolivegreen 626, 55 157, 13 156, 13 156, 17 157, 12 0.0622 0.12 0.605 0.2183 1.06 0.841 1.35 -0.0113 0.39 0.977 0.01019 0.989 0.46 2.12 0.32 0.372 0.39 0.409 1.38 0.664 2.86 -0.0524 0.4 0.896 0.0478 0.949 0.433 2.08 PRS_PLINK_0.001 FALSE 731.1 Osteitis deformans [Paget's disease of bone] Both 53 589 14 musculoskeletal darkolivegreen 589, 53 148, 13 147, 13 147, 15 147, 12 0.0533 0.123 0.665 0.1769 1.05 0.828 1.34 0.0697 0.397 0.861 0.06515 1.07 0.492 2.33 0.197 0.381 0.605 0.218 1.22 0.577 2.57 -0.0508 0.399 0.899 0.04635 0.95 0.434 2.08 PRS_PLINK_0.001 FALSE 732 Osteochondropathies Both 83 1056 14 musculoskeletal darkolivegreen 1056, 83 264, 13 264, 28 264, 21 264, 21 0.0491 0.068 0.47 0.3279 1.05 0.919 1.2 0.761 0.337 0.0239 1.622 2.14 1.11 4.14 0.448 0.349 0.199 0.7016 1.57 0.79 3.1 0.465 0.349 0.183 0.7384 1.59 0.803 3.16 PRS_PLINK_0.001 FALSE 732.1 Juvenile osteochondrosis Both 32 486 14 musculoskeletal darkolivegreen 486, 32 122, 6 121, 8 121, 7 122, 11 0.0902 0.116 0.435 0.3614 1.09 0.873 1.37 0.346 0.515 0.501 0.2998 1.41 0.515 3.88 0.109 0.519 0.833 0.07919 1.12 0.403 3.09 0.691 0.494 0.161 0.7922 2 0.759 5.25 PRS_PLINK_0.001 TRUE 732.7 Osteochondritis dissecans Both 6 133 14 musculoskeletal darkolivegreen 133, 6 34, 2 33, 1 33, 1 33, 2 -0.232 0.932 0.804 0.09488 0.793 0.128 4.93 -0.319 0.938 0.734 0.1344 0.727 0.116 4.57 0.108 0.85 0.899 0.04639 1.11 0.211 5.9 PRS_PLINK_0.001 TRUE 733 Other disorders of bone and cartilage Both 301 3767 14 musculoskeletal darkolivegreen 3767, 301 942, 67 942, 71 941, 75 942, 88 0.0652 0.037 0.0784 1.106 1.07 0.993 1.15 0.0604 0.175 0.73 0.1367 1.06 0.754 1.5 0.116 0.173 0.502 0.2992 1.12 0.8 1.58 0.258 0.167 0.122 0.912 1.29 0.933 1.8 PRS_PLINK_0.001 FALSE 733.2 Cyst of bone Both 54 644 14 musculoskeletal darkolivegreen 644, 54 161, 11 161, 15 161, 14 161, 14 0.0711 0.133 0.594 0.2262 1.07 0.827 1.39 0.301 0.399 0.451 0.3458 1.35 0.618 2.95 0.251 0.4 0.531 0.275 1.28 0.587 2.81 0.241 0.404 0.551 0.2592 1.27 0.576 2.81 PRS_PLINK_0.001 FALSE 733.4 Aseptic necrosis of bone Both 91 1093 14 musculoskeletal darkolivegreen 1093, 91 274, 26 273, 25 273, 23 273, 17 -0.571 0.353 0.106 0.9763 0.565 0.283 1.13 0.0162 0.291 0.956 0.01964 1.02 0.574 1.8 -0.0752 0.294 0.798 0.0978 0.928 0.521 1.65 -0.392 0.315 0.213 0.6711 0.676 0.365 1.25 PRS_PLINK_0.001 FALSE 733.6 Costochondritis Both 18 269 14 musculoskeletal darkolivegreen 269, 18 68, 4 67, 6 67, 4 67, 4 -0.295 0.79 0.709 0.1492 0.745 0.158 3.5 0.423 0.597 0.479 0.3201 1.53 0.474 4.92 -0.118 0.674 0.861 0.06512 0.888 0.237 3.33 -0.0661 0.67 0.921 0.03553 0.936 0.252 3.48 PRS_PLINK_0.001 TRUE 733.8 Malunion and nonunion of fracture Both 209 2665 14 musculoskeletal darkolivegreen 2665, 209 667, 48 666, 47 666, 63 666, 51 -0.00327 0.0834 0.969 0.01381 0.997 0.846 1.17 -0.0228 0.209 0.913 0.03939 0.977 0.648 1.47 0.297 0.198 0.134 0.8745 1.35 0.913 1.98 0.0354 0.206 0.863 0.06382 1.04 0.692 1.55 PRS_PLINK_0.001 FALSE 733.9 Chondromalacia Both 20 210 14 musculoskeletal darkolivegreen 210, 20 53, 4 52, 2 52, 5 53, 9 0.0726 0.118 0.537 0.27 1.08 0.854 1.35 -0.898 0.79 0.256 0.592 0.407 0.0866 1.92 0.204 0.754 0.787 0.1043 1.23 0.28 5.38 0.393 0.601 0.514 0.2893 1.48 0.456 4.81 PRS_PLINK_0.001 TRUE 735 Acquired foot deformities Both 1847 20306 14 musculoskeletal darkolivegreen 20306, 1847 5077, 463 5076, 467 5076, 460 5077, 457 -0.0164 0.0261 0.529 0.2762 0.984 0.935 1.04 0.00945 0.0684 0.89 0.05053 1.01 0.883 1.15 -0.00714 0.0687 0.917 0.03754 0.993 0.868 1.14 -0.0138 0.0688 0.841 0.07503 0.986 0.862 1.13 PRS_PLINK_0.001 FALSE 735.1 Flat foot Both 45 417 14 musculoskeletal darkolivegreen 417, 45 105, 12 104, 8 104, 17 104, 8 0.191 0.126 0.13 0.8854 1.21 0.945 1.55 -0.398 0.449 0.375 0.4255 0.672 0.279 1.62 0.356 0.389 0.36 0.444 1.43 0.666 3.06 -0.42 0.46 0.361 0.4424 0.657 0.267 1.62 PRS_PLINK_0.001 TRUE 735.2 Acquired toe deformities Both 931 10527 14 musculoskeletal darkolivegreen 10527, 931 2632, 243 2632, 247 2631, 217 2632, 224 -0.022 0.0429 0.607 0.2166 0.978 0.899 1.06 0.0173 0.0942 0.854 0.06833 1.02 0.846 1.22 -0.116 0.0972 0.232 0.6351 0.89 0.736 1.08 -0.0822 0.0964 0.394 0.4047 0.921 0.763 1.11 PRS_PLINK_0.001 FALSE 735.21 Hammer toe (acquired) Both 369 3974 14 musculoskeletal darkolivegreen 3974, 369 994, 108 993, 92 993, 84 994, 85 0.0189 0.0548 0.729 0.1371 1.02 0.915 1.13 -0.151 0.148 0.308 0.5115 0.86 0.643 1.15 -0.249 0.151 0.1 0.9996 0.779 0.579 1.05 -0.242 0.151 0.11 0.9589 0.785 0.584 1.06 PRS_PLINK_0.001 FALSE 735.23 Hallux rigidus Both 270 3293 14 musculoskeletal darkolivegreen 3293, 270 824, 68 823, 68 823, 67 823, 67 0.0304 0.0823 0.712 0.1474 1.03 0.877 1.21 0.0222 0.177 0.9 0.04559 1.02 0.723 1.45 0.00879 0.178 0.961 0.01742 1.01 0.711 1.43 -0.00632 0.177 0.972 0.01254 0.994 0.702 1.41 PRS_PLINK_0.001 FALSE 735.3 Hallux valgus (Bunion) Both 1303 14041 14 musculoskeletal darkolivegreen 14041, 1303 3511, 315 3510, 328 3510, 327 3510, 333 -0.00348 0.0287 0.903 0.04409 0.997 0.942 1.05 0.0416 0.0823 0.613 0.2126 1.04 0.887 1.22 0.0371 0.0823 0.652 0.1856 1.04 0.883 1.22 0.0548 0.082 0.504 0.2976 1.06 0.899 1.24 PRS_PLINK_0.001 FALSE 736 Other acquired deformities of limbs Both 264 3408 14 musculoskeletal darkolivegreen 3408, 264 852, 66 852, 68 852, 75 852, 55 0.0358 0.0517 0.489 0.311 1.04 0.937 1.15 0.0496 0.178 0.781 0.1076 1.05 0.741 1.49 0.13 0.174 0.455 0.3425 1.14 0.81 1.6 -0.187 0.187 0.316 0.5 0.829 0.575 1.2 PRS_PLINK_0.001 FALSE 736.2 Acquired deformities of finger Both 41 551 14 musculoskeletal darkolivegreen 551, 41 138, 5 138, 11 137, 15 138, 10 0.018 0.083 0.828 0.08188 1.02 0.865 1.2 0.691 0.508 0.173 0.7618 2 0.738 5.4 1.06 0.493 0.032 1.496 2.88 1.1 7.55 0.652 0.504 0.196 0.7078 1.92 0.715 5.15 PRS_PLINK_0.001 TRUE 737 Curvature of spine Both 189 2252 14 musculoskeletal darkolivegreen 2252, 189 563, 54 563, 45 563, 45 563, 45 0.0513 0.0502 0.307 0.513 1.05 0.954 1.16 -0.184 0.207 0.374 0.4272 0.832 0.554 1.25 -0.199 0.208 0.338 0.4708 0.819 0.545 1.23 -0.165 0.208 0.428 0.3687 0.848 0.564 1.27 PRS_PLINK_0.001 FALSE 737.3 Kyphoscoliosis and scoliosis Both 178 2106 14 musculoskeletal darkolivegreen 2106, 178 527, 53 526, 41 526, 41 527, 43 0.0474 0.0509 0.351 0.4545 1.05 0.949 1.16 -0.256 0.214 0.231 0.6364 0.774 0.51 1.18 -0.268 0.214 0.211 0.6766 0.765 0.503 1.16 -0.19 0.212 0.37 0.4316 0.827 0.546 1.25 PRS_PLINK_0.001 FALSE 738 Other acquired musculoskeletal deformity Both 342 3972 14 musculoskeletal darkolivegreen 3972, 342 993, 89 993, 96 993, 81 993, 76 -0.0624 0.0974 0.522 0.2824 0.94 0.776 1.14 0.0678 0.153 0.657 0.1824 1.07 0.793 1.44 -0.112 0.159 0.483 0.3161 0.894 0.655 1.22 -0.16 0.161 0.322 0.4925 0.852 0.621 1.17 PRS_PLINK_0.001 FALSE 738.4 Acquired spondylolisthesis Both 267 3047 14 musculoskeletal darkolivegreen 3047, 267 762, 66 762, 78 761, 59 762, 64 -0.0358 0.0811 0.659 0.181 0.965 0.823 1.13 0.147 0.174 0.397 0.401 1.16 0.824 1.63 -0.126 0.185 0.497 0.304 0.882 0.614 1.27 -0.034 0.181 0.851 0.07004 0.967 0.678 1.38 PRS_PLINK_0.001 FALSE 739 Contracture of joint Both 92 1019 14 musculoskeletal darkolivegreen 1019, 92 255, 21 255, 26 254, 30 255, 15 -0.316 0.366 0.388 0.4113 0.729 0.355 1.49 0.191 0.3 0.525 0.2796 1.21 0.672 2.18 0.332 0.291 0.255 0.5935 1.39 0.787 2.47 -0.377 0.339 0.265 0.5768 0.686 0.353 1.33 PRS_PLINK_0.001 FALSE 740 Osteoarthrosis Both 4824 49677 14 musculoskeletal darkolivegreen 49677, 4824 12420, 1194 12419, 1221 12419, 1118 12419, 1290 0.0279 0.0117 0.0171 1.767 1.03 1 1.05 0.0249 0.0427 0.561 0.2513 1.03 0.943 1.11 -0.0636 0.0436 0.145 0.8401 0.938 0.862 1.02 0.0803 0.0422 0.0569 1.245 1.08 0.998 1.18 PRS_PLINK_0.001 FALSE 740.1 Osteoarthritis; localized Both 3105 35211 14 musculoskeletal darkolivegreen 35211, 3105 8803, 797 8803, 752 8802, 748 8803, 807 0.0243 0.0155 0.118 0.9279 1.02 0.994 1.06 -0.057 0.053 0.282 0.549 0.945 0.851 1.05 -0.062 0.0531 0.243 0.6152 0.94 0.847 1.04 0.0131 0.0522 0.802 0.09591 1.01 0.915 1.12 PRS_PLINK_0.001 FALSE 740.11 Osteoarthrosis, localized, primary Both 1647 18233 14 musculoskeletal darkolivegreen 18233, 1647 4559, 450 4558, 386 4558, 390 4558, 421 0.0371 0.0194 0.0563 1.249 1.04 0.999 1.08 -0.152 0.0724 0.0364 1.439 0.859 0.746 0.99 -0.14 0.0722 0.0532 1.274 0.87 0.755 1 -0.0661 0.0709 0.352 0.4538 0.936 0.815 1.08 PRS_PLINK_0.001 FALSE 740.12 Osteoarthrosis, localized, secondary Both 64 714 14 musculoskeletal darkolivegreen 714, 64 179, 15 178, 22 178, 14 179, 13 0.0488 0.0968 0.614 0.2119 1.05 0.869 1.27 0.43 0.342 0.209 0.68 1.54 0.786 3.01 -0.0191 0.371 0.959 0.01824 0.981 0.474 2.03 -0.0493 0.389 0.899 0.04617 0.952 0.444 2.04 PRS_PLINK_0.001 FALSE 740.2 Osteoarthrosis, generalized Both 84 1232 14 musculoskeletal darkolivegreen 1232, 84 308, 21 308, 21 308, 18 308, 24 0.0893 0.0559 0.11 0.9592 1.09 0.98 1.22 0.00494 0.312 0.987 0.005523 1 0.545 1.85 -0.159 0.322 0.621 0.2071 0.853 0.454 1.6 0.126 0.302 0.676 0.1701 1.13 0.628 2.05 PRS_PLINK_0.001 FALSE 740.9 Osteoarthrosis NOS Both 2036 25220 14 musculoskeletal darkolivegreen 25220, 2036 6305, 479 6305, 549 6305, 443 6305, 565 0.0357 0.0169 0.0348 1.459 1.04 1 1.07 0.136 0.0649 0.0365 1.438 1.15 1.01 1.3 -0.0749 0.0682 0.272 0.5651 0.928 0.812 1.06 0.165 0.0645 0.0107 1.97 1.18 1.04 1.34 PRS_PLINK_0.001 FALSE 741 Symptoms and disorders of the joints Both 678 7634 14 musculoskeletal darkolivegreen 7634, 678 1909, 164 1908, 176 1908, 158 1909, 180 -0.0347 0.0545 0.525 0.2801 0.966 0.868 1.07 0.0677 0.113 0.549 0.2603 1.07 0.858 1.34 -0.0423 0.116 0.715 0.1458 0.959 0.764 1.2 0.0927 0.112 0.41 0.3877 1.1 0.88 1.37 PRS_PLINK_0.001 FALSE 741.1 Ankylosis of joint Both 21 223 14 musculoskeletal darkolivegreen 223, 21 56, 5 56, 7 55, 6 56, 3 -0.579 0.726 0.425 0.3716 0.56 0.135 2.33 0.438 0.599 0.465 0.3329 1.55 0.479 5.02 -0.196 0.621 0.753 0.1232 0.822 0.243 2.78 -0.238 0.681 0.727 0.1386 0.788 0.207 3 PRS_PLINK_0.001 TRUE 741.2 Stiffness of joint Both 109 1317 14 musculoskeletal darkolivegreen 1317, 109 330, 27 329, 32 329, 25 329, 25 -0.284 0.329 0.387 0.4118 0.753 0.395 1.43 0.162 0.266 0.544 0.2644 1.18 0.697 1.98 -0.131 0.285 0.645 0.1907 0.877 0.502 1.53 -0.122 0.282 0.666 0.1764 0.885 0.509 1.54 PRS_PLINK_0.001 FALSE 741.3 Difficulty in walking Both 25 323 14 musculoskeletal darkolivegreen 323, 25 81, 8 81, 3 80, 11 81, 3 -0.843 0.654 0.197 0.7047 0.43 0.119 1.55 -1 0.638 0.115 0.9382 0.366 0.105 1.28 0.279 0.471 0.553 0.2571 1.32 0.526 3.33 -1.05 0.668 0.115 0.9383 0.349 0.0943 1.29 PRS_PLINK_0.001 TRUE 741.4 Joint effusions Both 242 2948 14 musculoskeletal darkolivegreen 2948, 242 737, 58 737, 62 737, 52 737, 70 0.0173 0.0647 0.79 0.1025 1.02 0.896 1.15 0.0378 0.189 0.841 0.07514 1.04 0.717 1.5 -0.104 0.196 0.597 0.2244 0.901 0.614 1.32 0.195 0.183 0.287 0.542 1.22 0.849 1.74 PRS_PLINK_0.001 FALSE 741.5 Hemarthrosis Both 25 233 14 musculoskeletal darkolivegreen 233, 25 59, 6 58, 10 58, 5 58, 4 -0.765 0.728 0.294 0.532 0.466 0.112 1.94 0.25 0.544 0.646 0.1899 1.28 0.442 3.73 -0.289 0.6 0.631 0.2001 0.749 0.231 2.43 -0.23 0.609 0.706 0.1513 0.794 0.241 2.62 PRS_PLINK_0.001 TRUE 741.6 Villonodular synovitis Both 9 118 14 musculoskeletal darkolivegreen 118, 9 30, 5 29, 2 29, 1 30, 1 -1.12 1.05 0.287 0.5419 0.328 0.042 2.56 -0.615 0.758 0.418 0.3792 0.541 0.122 2.39 -1.31 0.913 0.151 0.8217 0.269 0.045 1.61 -1.15 0.87 0.186 0.7304 0.317 0.0576 1.74 PRS_PLINK_0.001 TRUE 742 Derangement of joint, non-traumatic Both 583 6343 14 musculoskeletal darkolivegreen 6343, 583 1586, 139 1586, 139 1585, 157 1586, 148 0.0303 0.034 0.373 0.4279 1.03 0.964 1.1 0.00957 0.125 0.939 0.02743 1.01 0.791 1.29 0.134 0.122 0.269 0.5706 1.14 0.901 1.45 0.0646 0.123 0.599 0.2225 1.07 0.838 1.36 PRS_PLINK_0.001 FALSE 742.1 Loose body in joint Both 61 734 14 musculoskeletal darkolivegreen 734, 61 184, 16 183, 21 183, 9 184, 15 0.0372 0.0741 0.616 0.2104 1.04 0.898 1.2 0.249 0.341 0.464 0.333 1.28 0.658 2.5 -0.422 0.412 0.306 0.515 0.656 0.293 1.47 -0.124 0.367 0.736 0.133 0.884 0.431 1.81 PRS_PLINK_0.001 FALSE 742.2 Pathological, developmental or recurrent dislocation Both 19 206 14 musculoskeletal darkolivegreen 206, 19 52, 2 51, 5 51, 6 52, 6 0.59 0.82 0.472 0.3263 1.8 0.362 9.01 0.427 0.724 0.555 0.2556 1.53 0.371 6.34 0.885 0.699 0.205 0.6874 2.42 0.616 9.55 0.648 0.705 0.358 0.4462 1.91 0.48 7.62 PRS_PLINK_0.001 TRUE 742.8 Articular cartilage disorder Both 92 1112 14 musculoskeletal darkolivegreen 1112, 92 278, 22 278, 18 278, 31 278, 21 0.0691 0.0536 0.198 0.704 1.07 0.965 1.19 -0.192 0.321 0.551 0.259 0.826 0.44 1.55 0.359 0.285 0.209 0.6796 1.43 0.818 2.5 -0.0461 0.31 0.882 0.05458 0.955 0.52 1.75 PRS_PLINK_0.001 FALSE 742.9 Other derangement of joint Both 415 4450 14 musculoskeletal darkolivegreen 4450, 415 1113, 105 1112, 91 1112, 112 1113, 107 0.0209 0.0411 0.611 0.2139 1.02 0.942 1.11 -0.134 0.148 0.365 0.4373 0.874 0.654 1.17 0.077 0.142 0.587 0.2313 1.08 0.818 1.43 0.01 0.143 0.944 0.02498 1.01 0.763 1.34 PRS_PLINK_0.001 FALSE 743 Osteoporosis, osteopenia and pathological fracture Both 1255 15042 14 musculoskeletal darkolivegreen 15042, 1255 3761, 285 3760, 314 3760, 326 3761, 330 0.0106 0.0237 0.654 0.1842 1.01 0.965 1.06 0.1 0.0849 0.239 0.6217 1.11 0.936 1.31 0.139 0.0842 0.0975 1.011 1.15 0.975 1.36 0.148 0.084 0.0787 1.104 1.16 0.983 1.37 PRS_PLINK_0.001 FALSE 743.1 Osteoporosis Both 1055 12551 14 musculoskeletal darkolivegreen 12551, 1055 3138, 252 3138, 257 3137, 266 3138, 280 0.0138 0.0245 0.575 0.2404 1.01 0.966 1.06 0.0237 0.092 0.797 0.09859 1.02 0.855 1.23 0.0569 0.0912 0.533 0.2733 1.06 0.885 1.27 0.107 0.0903 0.234 0.6307 1.11 0.933 1.33 PRS_PLINK_0.001 FALSE 743.11 Osteoporosis NOS Both 925 10847 14 musculoskeletal darkolivegreen 10847, 925 2712, 215 2712, 224 2711, 246 2712, 240 0.0211 0.0249 0.396 0.4018 1.02 0.973 1.07 0.0459 0.0991 0.643 0.1915 1.05 0.862 1.27 0.139 0.097 0.152 0.8186 1.15 0.95 1.39 0.113 0.0975 0.247 0.6074 1.12 0.925 1.36 PRS_PLINK_0.001 FALSE 743.13 Other specified osteoporosis Both 89 1106 14 musculoskeletal darkolivegreen 1106, 89 277, 24 276, 21 276, 16 277, 28 0.024 0.0807 0.766 0.1156 1.02 0.874 1.2 -0.13 0.3 0.665 0.1774 0.878 0.487 1.58 -0.45 0.325 0.166 0.7788 0.637 0.337 1.21 0.151 0.285 0.596 0.2245 1.16 0.665 2.03 PRS_PLINK_0.001 FALSE 743.2 Pathologic fracture Both 73 1095 14 musculoskeletal darkolivegreen 1095, 73 274, 14 274, 23 273, 18 274, 18 0.0263 0.0887 0.767 0.1154 1.03 0.863 1.22 0.482 0.339 0.155 0.8085 1.62 0.833 3.15 0.313 0.352 0.375 0.4264 1.37 0.685 2.73 0.259 0.35 0.459 0.3379 1.3 0.652 2.58 PRS_PLINK_0.001 FALSE 743.9 Osteopenia or other disorder of bone and cartilage Both 145 1718 14 musculoskeletal darkolivegreen 1718, 145 430, 21 429, 40 429, 46 430, 38 0.0272 0.0655 0.678 0.1685 1.03 0.904 1.17 0.633 0.274 0.0209 1.679 1.88 1.1 3.22 0.834 0.268 0.00185 2.734 2.3 1.36 3.89 0.589 0.274 0.0314 1.504 1.8 1.05 3.08 PRS_PLINK_0.001 FALSE 745 Pain in joint Both 1367 17083 14 musculoskeletal darkolivegreen 17083, 1367 4271, 315 4271, 347 4270, 352 4271, 353 0.015 0.0222 0.498 0.3031 1.02 0.972 1.06 0.1 0.0807 0.214 0.6691 1.11 0.944 1.29 0.112 0.0804 0.164 0.7849 1.12 0.955 1.31 0.111 0.0803 0.166 0.7803 1.12 0.955 1.31 PRS_PLINK_0.001 FALSE 747 Cardiac and circulatory congenital anomalies Both 438 5724 15 congenital anomalies mediumspringgreen 5724, 438 1431, 81 1431, 138 1431, 119 1431, 100 0.0309 0.0406 0.446 0.3503 1.03 0.952 1.12 0.529 0.144 0.000234 3.63 1.7 1.28 2.25 0.377 0.148 0.0108 1.966 1.46 1.09 1.95 0.215 0.153 0.159 0.7993 1.24 0.919 1.67 PRS_PLINK_0.001 FALSE 747.1 Cardiac congenital anomalies Both 407 5415 15 congenital anomalies mediumspringgreen 5415, 407 1354, 77 1354, 124 1353, 114 1354, 92 0.0251 0.0414 0.544 0.2642 1.03 0.946 1.11 0.473 0.149 0.00149 2.827 1.61 1.2 2.15 0.385 0.151 0.011 1.96 1.47 1.09 1.98 0.178 0.158 0.26 0.5852 1.19 0.877 1.63 PRS_PLINK_0.001 FALSE 747.11 Cardiac shunt/ heart septal defect Both 116 1241 15 congenital anomalies mediumspringgreen 1241, 116 311, 20 310, 30 310, 39 310, 27 0.0947 0.0546 0.0831 1.081 1.1 0.988 1.22 0.403 0.292 0.168 0.7743 1.5 0.844 2.65 0.696 0.282 0.0136 1.866 2.01 1.15 3.49 0.295 0.3 0.325 0.4886 1.34 0.746 2.42 PRS_PLINK_0.001 FALSE 747.12 Valvular heart disease/ heart chambers Both 45 522 15 congenital anomalies mediumspringgreen 522, 45 131, 6 130, 14 130, 13 131, 12 0.668 0.479 0.163 0.7872 1.95 0.763 4.99 0.883 0.484 0.0683 1.165 2.42 0.936 6.24 0.76 0.475 0.109 0.9618 2.14 0.844 5.42 0.654 0.48 0.173 0.763 1.92 0.751 4.93 PRS_PLINK_0.001 TRUE 747.13 Congenital anomalies of great vessels Both 259 3650 15 congenital anomalies mediumspringgreen 3650, 259 913, 54 912, 80 912, 70 913, 55 -0.0421 0.076 0.58 0.2365 0.959 0.826 1.11 0.391 0.18 0.0301 1.521 1.48 1.04 2.1 0.256 0.185 0.166 0.7789 1.29 0.899 1.85 0.0063 0.194 0.974 0.01137 1.01 0.687 1.47 PRS_PLINK_0.001 FALSE 747.2 Congenital anomalies of peripheral vascular system Both 30 310 15 congenital anomalies mediumspringgreen 310, 30 78, 3 77, 11 77, 6 78, 10 0.994 0.59 0.0923 1.035 2.7 0.849 8.59 1.14 0.593 0.0549 1.26 3.12 0.976 9.97 0.468 0.646 0.469 0.3288 1.6 0.45 5.66 0.96 0.599 0.109 0.9636 2.61 0.808 8.45 PRS_PLINK_0.001 TRUE 748 Anomalies of respiratory system, congenital Both 12 101 15 congenital anomalies mediumspringgreen 101, 12 26, 3 25, 6 25, 1 25, 2 -0.792 1.18 0.503 0.2986 0.453 0.0446 4.6 0.943 0.837 0.26 0.5851 2.57 0.498 13.3 -1.56 1.08 0.148 0.8298 0.21 0.0253 1.74 -0.776 0.873 0.374 0.4273 0.46 0.0831 2.55 PRS_PLINK_0.001 TRUE 749 Congenital anomalies of face and neck Both 51 639 15 congenital anomalies mediumspringgreen 639, 51 160, 13 160, 7 159, 19 160, 12 0.0552 0.116 0.634 0.1981 1.06 0.842 1.33 -0.523 0.452 0.247 0.607 0.593 0.244 1.44 0.467 0.371 0.208 0.6814 1.59 0.771 3.3 -0.172 0.402 0.669 0.1744 0.842 0.383 1.85 PRS_PLINK_0.001 FALSE 750 Digestive congenital anomalies Both 128 1442 15 congenital anomalies mediumspringgreen 1442, 128 361, 27 360, 32 360, 41 361, 28 0.0167 0.0779 0.83 0.08092 1.02 0.873 1.18 0.156 0.266 0.559 0.2529 1.17 0.693 1.97 0.427 0.255 0.0938 1.028 1.53 0.93 2.53 0.0446 0.273 0.87 0.06033 1.05 0.612 1.79 PRS_PLINK_0.001 FALSE 750.1 Upper gastrointestinal congenital anomalies Both 55 696 15 congenital anomalies mediumspringgreen 696, 55 174, 13 174, 15 174, 16 174, 11 0.0387 0.096 0.687 0.1633 1.04 0.861 1.25 0.0873 0.384 0.82 0.08614 1.09 0.514 2.32 0.212 0.381 0.577 0.2389 1.24 0.587 2.61 -0.177 0.415 0.67 0.1742 0.838 0.371 1.89 PRS_PLINK_0.001 FALSE 750.13 Congenital anomalies of mouth/tongue Both 33 395 15 congenital anomalies mediumspringgreen 395, 33 99, 8 99, 7 98, 11 99, 7 -0.0059 0.0877 0.946 0.02393 0.994 0.837 1.18 -0.204 0.518 0.694 0.1585 0.816 0.296 2.25 0.207 0.484 0.668 0.175 1.23 0.477 3.18 -0.403 0.56 0.471 0.3265 0.668 0.223 2 PRS_PLINK_0.001 TRUE 750.2 Lower gastrointestinal congenital anomalies Both 72 755 15 congenital anomalies mediumspringgreen 755, 72 189, 16 189, 17 188, 23 189, 16 0.0144 0.0864 0.868 0.06148 1.01 0.856 1.2 0.0597 0.35 0.864 0.06328 1.06 0.535 2.11 0.369 0.331 0.265 0.5767 1.45 0.756 2.77 0.0509 0.355 0.886 0.05254 1.05 0.524 2.11 PRS_PLINK_0.001 FALSE 750.21 Congenital anomalies of intestine Both 41 488 15 congenital anomalies mediumspringgreen 488, 41 122, 8 122, 10 122, 11 122, 12 0.0793 0.113 0.485 0.3144 1.08 0.867 1.35 0.226 0.471 0.632 0.1996 1.25 0.498 3.15 0.309 0.446 0.488 0.3118 1.36 0.569 3.27 0.488 0.451 0.28 0.5531 1.63 0.672 3.94 PRS_PLINK_0.001 TRUE 750.22 Congenital anomaly of gallbladder, bile ducts, liver, pancreas Both 29 239 15 congenital anomalies mediumspringgreen 239, 29 60, 9 60, 8 59, 8 60, 4 -0.517 0.723 0.475 0.3234 0.596 0.144 2.46 0.0282 0.501 0.955 0.01999 1.03 0.386 2.74 -0.11 0.494 0.824 0.0839 0.896 0.341 2.36 -0.563 0.597 0.346 0.4613 0.57 0.177 1.83 PRS_PLINK_0.001 TRUE 751 Genitourinary congenital anomalies Both 316 3334 15 congenital anomalies mediumspringgreen 3334, 316 834, 82 833, 81 833, 83 834, 70 -0.0745 0.113 0.511 0.2916 0.928 0.743 1.16 -0.00811 0.163 0.96 0.01756 0.992 0.72 1.37 0.00477 0.162 0.977 0.01032 1 0.731 1.38 -0.168 0.169 0.32 0.4946 0.845 0.607 1.18 PRS_PLINK_0.001 FALSE 751.1 Congenital anomalies of genital organs Both 148 1556 15 congenital anomalies mediumspringgreen 1556, 148 389, 32 389, 37 389, 36 389, 43 0.27 0.206 0.188 0.7254 1.31 0.876 1.96 0.117 0.248 0.637 0.1961 1.12 0.692 1.83 0.123 0.25 0.623 0.2055 1.13 0.693 1.85 0.278 0.242 0.25 0.6016 1.32 0.822 2.12 PRS_PLINK_0.001 FALSE 751.11 Congenital anomalies of female genital organs Female 96 1044 15 congenital anomalies mediumspringgreen 1044, 96 261, 21 261, 20 261, 26 261, 29 0.669 0.353 0.0579 1.238 1.95 0.978 3.9 -0.0398 0.315 0.899 0.04609 0.961 0.518 1.78 0.277 0.302 0.36 0.4433 1.32 0.729 2.38 0.35 0.294 0.235 0.6296 1.42 0.797 2.53 PRS_PLINK_0.001 FALSE 751.12 Congenital anomalies of male genital organs Male 45 476 15 congenital anomalies mediumspringgreen 476, 45 119, 8 119, 18 119, 9 119, 10 0.0338 0.0917 0.712 0.1475 1.03 0.864 1.24 0.669 0.43 0.12 0.922 1.95 0.841 4.53 0.169 0.483 0.726 0.1388 1.18 0.46 3.05 0.172 0.467 0.712 0.1474 1.19 0.476 2.96 PRS_PLINK_0.001 TRUE 751.2 Congenital anomalies of urinary system Both 165 1782 15 congenital anomalies mediumspringgreen 1782, 165 446, 50 445, 45 445, 42 446, 28 -0.748 0.281 0.00775 2.11 0.473 0.273 0.821 -0.106 0.217 0.624 0.2049 0.899 0.588 1.37 -0.194 0.217 0.372 0.4297 0.824 0.538 1.26 -0.583 0.242 0.0162 1.791 0.558 0.347 0.898 PRS_PLINK_0.001 FALSE 751.21 Cystic kidney disease Both 89 900 15 congenital anomalies mediumspringgreen 900, 89 225, 26 225, 31 225, 18 225, 14 -0.926 0.391 0.0179 1.747 0.396 0.184 0.853 0.146 0.279 0.6 0.2219 1.16 0.67 2 -0.419 0.317 0.186 0.7303 0.658 0.354 1.22 -0.606 0.342 0.0762 1.118 0.545 0.279 1.07 PRS_PLINK_0.001 FALSE 751.22 Other specified congenital anomalies of kidney Both 59 752 15 congenital anomalies mediumspringgreen 752, 59 188, 17 188, 12 188, 20 188, 10 -0.722 0.456 0.113 0.9474 0.486 0.199 1.19 -0.359 0.384 0.349 0.4573 0.698 0.329 1.48 0.105 0.338 0.755 0.122 1.11 0.573 2.15 -0.583 0.396 0.141 0.8521 0.558 0.257 1.21 PRS_PLINK_0.001 FALSE 752 Nervous system congenital anomalies Both 49 723 15 congenital anomalies mediumspringgreen 723, 49 181, 11 181, 14 180, 10 181, 14 0.015 0.0834 0.857 0.06694 1.02 0.862 1.2 0.299 0.407 0.464 0.3338 1.35 0.607 3 0.0112 0.427 0.979 0.009213 1.01 0.438 2.33 0.229 0.399 0.566 0.2471 1.26 0.576 2.75 PRS_PLINK_0.001 TRUE 752.1 Neural tube defects Both 37 566 15 congenital anomalies mediumspringgreen 566, 37 142, 9 141, 9 141, 7 142, 12 0.0415 0.0958 0.665 0.1775 1.04 0.864 1.26 0.111 0.461 0.81 0.09162 1.12 0.452 2.76 0.0532 0.492 0.914 0.0391 1.05 0.402 2.76 0.336 0.433 0.438 0.3582 1.4 0.599 3.27 PRS_PLINK_0.001 TRUE 752.11 Spina bifida Both 33 477 15 congenital anomalies mediumspringgreen 477, 33 120, 10 119, 7 119, 6 119, 10 0.0269 0.0981 0.784 0.1059 1.03 0.848 1.25 -0.346 0.488 0.478 0.3206 0.708 0.272 1.84 -0.237 0.508 0.641 0.1932 0.789 0.292 2.14 0.111 0.441 0.802 0.0958 1.12 0.47 2.65 PRS_PLINK_0.001 TRUE 752.2 Other specified congenital anomalies of nervous system Both 12 176 15 congenital anomalies mediumspringgreen 176, 12 44, 2 44, 5 44, 2 44, 3 -3.1 0.918 0.000737 3.132 0.0451 0.00745 0.273 0.631 0.715 0.378 0.4225 1.88 0.462 7.63 0.0115 0.793 0.988 0.005047 1.01 0.214 4.79 0.452 0.875 0.606 0.2175 1.57 0.282 8.73 PRS_PLINK_0.001 TRUE 753 Congenital anomalies of the eye Both 25 292 15 congenital anomalies mediumspringgreen 292, 25 73, 6 73, 5 73, 7 73, 7 0.0214 0.121 0.86 0.06544 1.02 0.806 1.3 -0.125 0.602 0.836 0.07794 0.883 0.271 2.87 0.232 0.553 0.676 0.1703 1.26 0.426 3.73 0.206 0.554 0.709 0.1491 1.23 0.415 3.64 PRS_PLINK_0.001 TRUE 753.1 Congenital cataract and lens anomalies Both 13 174 15 congenital anomalies mediumspringgreen 174, 13 44, 3 43, 1 43, 5 44, 4 -0.381 0.9 0.672 0.1728 0.683 0.117 3.99 0.23 0.693 0.74 0.131 1.26 0.323 4.9 0.403 0.725 0.579 0.2377 1.5 0.361 6.19 PRS_PLINK_0.001 TRUE 754 Congenital musculoskeletal deformities of spine Both 19 237 15 congenital anomalies mediumspringgreen 237, 19 60, 2 59, 5 59, 5 59, 7 1.36 0.81 0.0922 1.035 3.91 0.8 19.2 0.738 0.69 0.285 0.5454 2.09 0.541 8.09 0.822 0.71 0.247 0.6073 2.27 0.566 9.15 1.23 0.714 0.085 1.07 3.42 0.844 13.9 PRS_PLINK_0.001 TRUE 755 Congenital anomalies of limbs Both 80 904 15 congenital anomalies mediumspringgreen 904, 80 226, 21 226, 17 226, 21 226, 21 0.0175 0.0895 0.845 0.07293 1.02 0.854 1.21 -0.207 0.33 0.531 0.2753 0.813 0.426 1.55 -0.000766 0.314 0.998 0.0008476 0.999 0.54 1.85 -0.0348 0.315 0.912 0.04009 0.966 0.521 1.79 PRS_PLINK_0.001 FALSE 755.1 Congenital deformities of feet Both 40 439 15 congenital anomalies mediumspringgreen 439, 40 110, 11 110, 8 109, 10 110, 11 0.0167 0.0941 0.859 0.06585 1.02 0.846 1.22 -0.4 0.472 0.396 0.4021 0.67 0.266 1.69 -0.0414 0.443 0.926 0.0336 0.959 0.402 2.29 0.131 0.443 0.767 0.1153 1.14 0.479 2.72 PRS_PLINK_0.001 TRUE 755.6 Other congenital anomalies of lower limb, including pelvic girdle Both 28 352 15 congenital anomalies mediumspringgreen 352, 28 88, 6 88, 7 88, 7 88, 8 -0.0469 0.332 0.888 0.05179 0.954 0.498 1.83 0.123 0.529 0.816 0.08818 1.13 0.401 3.19 0.194 0.541 0.72 0.1427 1.21 0.42 3.51 -0.0867 0.542 0.873 0.05907 0.917 0.317 2.65 PRS_PLINK_0.001 TRUE 755.61 Congenital hip dysplasia and deformity Both 16 238 15 congenital anomalies mediumspringgreen 238, 16 60, 2 59, 5 59, 4 60, 5 0.135 0.136 0.322 0.4924 1.14 0.876 1.5 0.604 0.696 0.386 0.4136 1.83 0.467 7.16 0.496 0.73 0.497 0.3038 1.64 0.393 6.86 0.416 0.714 0.56 0.2519 1.52 0.374 6.14 PRS_PLINK_0.001 TRUE 756 Other congenital musculoskeletal anomalies Both 103 1253 15 congenital anomalies mediumspringgreen 1253, 103 314, 27 313, 23 313, 24 313, 29 0.0632 0.105 0.549 0.2607 1.07 0.867 1.31 -0.181 0.288 0.531 0.2752 0.835 0.475 1.47 -0.141 0.285 0.621 0.2071 0.868 0.496 1.52 0.103 0.274 0.706 0.1511 1.11 0.648 1.9 PRS_PLINK_0.001 FALSE 756.3 Congenital anomalies of muscle, tendon, fascia, and connective tissue Both 21 166 15 congenital anomalies mediumspringgreen 166, 21 42, 8 41, 2 41, 4 42, 7 0.397 0.692 0.566 0.2472 1.49 0.383 5.78 -1.29 0.717 0.071 1.149 0.274 0.0672 1.12 -0.7 0.619 0.258 0.5884 0.496 0.148 1.67 -0.441 0.6 0.462 0.3352 0.643 0.198 2.09 PRS_PLINK_0.001 TRUE 756.5 Congenital osteodystrophies Both 67 920 15 congenital anomalies mediumspringgreen 920, 67 230, 13 230, 18 230, 18 230, 18 0.0347 0.0813 0.669 0.1745 1.04 0.883 1.21 0.289 0.363 0.426 0.3708 1.34 0.655 2.72 0.278 0.36 0.441 0.3558 1.32 0.652 2.67 0.35 0.359 0.33 0.4813 1.42 0.702 2.87 PRS_PLINK_0.001 FALSE 758 Chromosomal anomalies and genetic disorders Both 29 372 15 congenital anomalies mediumspringgreen 372, 29 93, 5 93, 10 93, 6 93, 8 0.00567 0.623 0.993 0.003164 1.01 0.297 3.41 0.719 0.534 0.178 0.7503 2.05 0.721 5.85 0.0401 0.574 0.944 0.02487 1.04 0.338 3.21 0.499 0.544 0.359 0.4446 1.65 0.567 4.78 PRS_PLINK_0.001 TRUE 758.1 Chromosomal anomalies Both 7 177 15 congenital anomalies mediumspringgreen 177, 7 45, 2 44, 0 44, 2 44, 3 0.245 1.07 0.819 0.08647 1.28 0.156 10.4 -1.05 1.25 0.401 0.3968 0.35 0.0301 4.06 -0.259 0.848 0.76 0.119 0.772 0.146 4.07 0.59 0.825 0.475 0.3238 1.8 0.358 9.09 PRS_PLINK_0.001 TRUE 759 Other and unspecified congenital anomalies Both 42 436 15 congenital anomalies mediumspringgreen 436, 42 109, 8 109, 10 109, 8 109, 16 0.458 0.428 0.285 0.5458 1.58 0.683 3.66 0.0859 0.469 0.855 0.06816 1.09 0.435 2.73 -0.174 0.503 0.73 0.1369 0.841 0.314 2.25 0.616 0.442 0.163 0.7869 1.85 0.779 4.4 PRS_PLINK_0.001 TRUE 759.1 Anomalies of endocrine glands, congenital Both 22 185 15 congenital anomalies mediumspringgreen 185, 22 47, 8 46, 3 46, 3 46, 8 -0.595 0.726 0.412 0.385 0.551 0.133 2.29 -0.801 0.648 0.216 0.6648 0.449 0.126 1.6 -0.997 0.667 0.135 0.8692 0.369 0.0998 1.36 -0.00534 0.563 0.992 0.0033 0.995 0.33 3 PRS_PLINK_0.001 TRUE 760 Back pain Both 1830 23639 17 symptoms purple 23639, 1830 5910, 443 5910, 465 5909, 453 5910, 469 0.0162 0.0204 0.427 0.3697 1.02 0.977 1.06 0.0476 0.0688 0.489 0.3108 1.05 0.916 1.2 0.0169 0.0692 0.807 0.0933 1.02 0.888 1.16 0.0554 0.0687 0.42 0.3767 1.06 0.924 1.21 PRS_PLINK_0.001 FALSE 761 Cervicalgia Both 284 3800 17 symptoms purple 3800, 284 950, 76 950, 72 950, 67 950, 69 -0.359 0.202 0.0756 1.122 0.698 0.47 1.04 -0.0513 0.169 0.761 0.1184 0.95 0.682 1.32 -0.118 0.173 0.494 0.3064 0.888 0.633 1.25 -0.104 0.171 0.543 0.2649 0.901 0.645 1.26 PRS_PLINK_0.001 FALSE 764 Sciatica Both 393 4975 17 symptoms purple 4975, 393 1244, 82 1244, 112 1243, 91 1244, 108 0.00915 0.0544 0.866 0.06225 1.01 0.907 1.12 0.327 0.15 0.0292 1.535 1.39 1.03 1.86 0.0967 0.157 0.537 0.2702 1.1 0.81 1.5 0.281 0.151 0.0622 1.206 1.32 0.986 1.78 PRS_PLINK_0.001 FALSE 766 Neuralgia, neuritis, and radiculitis NOS Both 192 2472 17 symptoms purple 2472, 192 618, 37 618, 56 618, 51 618, 48 0.0234 0.0695 0.736 0.1331 1.02 0.893 1.17 0.419 0.217 0.053 1.276 1.52 0.995 2.33 0.345 0.221 0.119 0.9257 1.41 0.916 2.18 0.247 0.222 0.267 0.5728 1.28 0.828 1.98 PRS_PLINK_0.001 FALSE 770 Myalgia and myositis unspecified Both 104 1353 17 symptoms purple 1353, 104 339, 21 338, 28 338, 24 338, 31 0.0438 0.0436 0.315 0.5017 1.04 0.959 1.14 0.283 0.29 0.328 0.4845 1.33 0.753 2.34 0.152 0.299 0.611 0.2137 1.16 0.648 2.09 0.34 0.287 0.235 0.629 1.41 0.801 2.47 PRS_PLINK_0.001 FALSE 771 Musculoskeletal symptoms referable to limbs Both 162 1841 17 symptoms purple 1841, 162 461, 41 460, 30 460, 40 460, 51 0.009 0.0676 0.894 0.0486 1.01 0.884 1.15 -0.336 0.246 0.171 0.7666 0.714 0.441 1.16 -0.0261 0.228 0.909 0.0414 0.974 0.623 1.52 0.225 0.217 0.299 0.5245 1.25 0.819 1.92 PRS_PLINK_0.001 FALSE 771.1 Swelling of limb Both 795 9537 17 symptoms purple 9537, 795 2385, 200 2384, 191 2384, 207 2384, 197 0.00899 0.0308 0.77 0.1132 1.01 0.95 1.07 -0.0404 0.105 0.7 0.155 0.96 0.782 1.18 0.0283 0.103 0.784 0.1058 1.03 0.841 1.26 -0.0192 0.104 0.853 0.06881 0.981 0.8 1.2 PRS_PLINK_0.001 FALSE 772 Symptoms of the muscles Both 106 1365 17 symptoms purple 1365, 106 342, 34 341, 23 341, 23 341, 26 0.083 0.061 0.174 0.7603 1.09 0.964 1.22 -0.41 0.276 0.136 0.8649 0.663 0.386 1.14 -0.369 0.275 0.18 0.745 0.691 0.403 1.19 -0.243 0.266 0.361 0.4429 0.784 0.466 1.32 PRS_PLINK_0.001 FALSE 773 Pain in limb Both 1046 13058 17 symptoms purple 13058, 1046 3265, 249 3264, 263 3264, 269 3265, 265 0.0213 0.0275 0.438 0.3581 1.02 0.968 1.08 0.0572 0.0916 0.533 0.2737 1.06 0.885 1.27 0.0761 0.0911 0.404 0.394 1.08 0.903 1.29 0.0651 0.0914 0.477 0.3219 1.07 0.892 1.28 PRS_PLINK_0.001 FALSE 780 Hypothermia/Chills Both 18 351 17 symptoms purple 351, 18 88, 7 88, 4 87, 5 88, 2 -1.01 0.761 0.185 0.7329 0.365 0.0821 1.62 -0.379 0.589 0.52 0.2836 0.685 0.216 2.17 0.194 0.616 0.753 0.1233 1.21 0.363 4.06 -0.895 0.671 0.182 0.7401 0.409 0.11 1.52 PRS_PLINK_0.001 TRUE 781 Symptoms involving nervous and musculoskeletal systems Both 337 4048 17 symptoms purple 4048, 337 1012, 73 1012, 81 1012, 95 1012, 88 0.0156 0.0615 0.799 0.09732 1.02 0.9 1.15 0.105 0.166 0.527 0.278 1.11 0.802 1.54 0.269 0.161 0.0941 1.027 1.31 0.955 1.79 0.193 0.163 0.238 0.6241 1.21 0.881 1.67 PRS_PLINK_0.001 FALSE 782.3 Edema Both 217 3417 17 symptoms purple 3417, 217 855, 48 854, 44 854, 60 854, 65 0.0575 0.0441 0.193 0.7154 1.06 0.971 1.15 -0.111 0.211 0.599 0.2229 0.895 0.591 1.35 0.218 0.197 0.269 0.5703 1.24 0.845 1.83 0.28 0.194 0.15 0.8241 1.32 0.904 1.94 PRS_PLINK_0.001 FALSE 782.6 Pallor and flushing Both 28 367 17 symptoms purple 367, 28 92, 7 92, 5 91, 9 92, 7 0.0546 0.103 0.596 0.2244 1.06 0.863 1.29 -0.257 0.54 0.634 0.1979 0.773 0.268 2.23 0.0274 0.515 0.958 0.0188 1.03 0.374 2.82 0.0164 0.52 0.975 0.01105 1.02 0.367 2.81 PRS_PLINK_0.001 TRUE 783 Fever of unknown origin Both 703 8443 17 symptoms purple 8443, 703 2111, 173 2111, 181 2110, 164 2111, 185 -0.00499 0.0426 0.907 0.04249 0.995 0.915 1.08 0.0452 0.11 0.682 0.1661 1.05 0.843 1.3 -0.0551 0.113 0.625 0.2039 0.946 0.759 1.18 0.0622 0.11 0.571 0.2434 1.06 0.858 1.32 PRS_PLINK_0.001 FALSE 785 Abdominal pain Both 7433 66002 17 symptoms purple 66002, 7433 16501, 1776 16500, 1862 16500, 1896 16501, 1898 0.00844 0.0111 0.447 0.3493 1.01 0.987 1.03 0.0469 0.035 0.18 0.7443 1.05 0.979 1.12 0.0653 0.0349 0.0612 1.213 1.07 0.997 1.14 0.066 0.0349 0.0585 1.233 1.07 0.998 1.14 PRS_PLINK_0.001 FALSE 788 Syncope and collapse Both 1527 18863 17 symptoms purple 18863, 1527 4716, 365 4716, 369 4715, 400 4716, 393 0.02 0.023 0.383 0.4164 1.02 0.975 1.07 0.00757 0.0765 0.921 0.03566 1.01 0.867 1.17 0.0917 0.0751 0.222 0.6532 1.1 0.946 1.27 0.0732 0.0754 0.332 0.4794 1.08 0.928 1.25 PRS_PLINK_0.001 FALSE 789 Nausea and vomiting Both 1872 24410 17 symptoms purple 24410, 1872 6103, 449 6102, 477 6102, 452 6103, 494 0.043 0.0168 0.0103 1.988 1.04 1.01 1.08 0.06 0.0681 0.378 0.4221 1.06 0.929 1.21 0.00599 0.069 0.931 0.03113 1.01 0.879 1.15 0.0943 0.0676 0.163 0.7879 1.1 0.963 1.25 PRS_PLINK_0.001 FALSE 790 Nonspecific findings on examination of blood Both 25 323 17 symptoms purple 323, 25 81, 5 81, 6 80, 6 81, 8 0.847 0.72 0.24 0.6201 2.33 0.568 9.57 -0.107 0.587 0.855 0.06816 0.898 0.284 2.84 0.173 0.58 0.765 0.1161 1.19 0.381 3.71 0.547 0.555 0.324 0.4893 1.73 0.582 5.13 PRS_PLINK_0.001 TRUE 790.1 Elevated sedimentation rate Both 12 171 17 symptoms purple 171, 12 43, 1 43, 2 42, 4 43, 5 1.96 0.992 0.0481 1.318 7.11 1.02 49.7 0.23 0.896 0.797 0.09849 1.26 0.218 7.28 0.979 0.876 0.264 0.5788 2.66 0.478 14.8 0.615 0.929 0.508 0.2943 1.85 0.299 11.4 PRS_PLINK_0.001 TRUE 790.6 Other abnormal blood chemistry Both 1245 13394 17 symptoms purple 13394, 1245 3349, 297 3348, 305 3348, 312 3349, 331 -0.00873 0.0306 0.775 0.1106 0.991 0.934 1.05 0.0255 0.085 0.764 0.1167 1.03 0.868 1.21 0.0436 0.0846 0.606 0.2177 1.04 0.885 1.23 0.105 0.0834 0.207 0.6837 1.11 0.943 1.31 PRS_PLINK_0.001 FALSE 791 Gangrene Both 84 1184 17 symptoms purple 1184, 84 296, 28 296, 22 296, 11 296, 23 0.0642 0.0561 0.252 0.5981 1.07 0.955 1.19 -0.228 0.29 0.432 0.3647 0.796 0.451 1.41 -0.908 0.352 0.00986 2.006 0.403 0.202 0.804 -0.205 0.286 0.473 0.3252 0.815 0.465 1.43 PRS_PLINK_0.001 FALSE 792 Abnormal Papanicolaou smear of cervix and cervical HPV Female 13 192 17 symptoms purple 192, 13 48, 3 48, 2 48, 6 48, 2 0.384 0.958 0.689 0.162 1.47 0.225 9.59 0.563 0.995 0.571 0.2431 1.76 0.25 12.4 0.735 0.664 0.269 0.5707 2.08 0.567 7.66 -0.14 0.912 0.878 0.05653 0.869 0.145 5.2 PRS_PLINK_0.001 TRUE 793 Nonspecific abnormal findings on radiological and other examination of musculoskeletal system Both 24 267 17 symptoms purple 267, 24 67, 8 67, 2 66, 5 67, 9 0.148 0.695 0.832 0.08013 1.16 0.297 4.53 -1.04 0.671 0.122 0.914 0.354 0.0951 1.32 -0.327 0.561 0.559 0.2524 0.721 0.24 2.16 0.235 0.505 0.642 0.1923 1.26 0.47 3.4 PRS_PLINK_0.001 TRUE 793.2 Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc) Both 95 1178 17 symptoms purple 1178, 95 295, 32 294, 21 294, 20 295, 22 0.0179 0.104 0.863 0.06404 1.02 0.831 1.25 -0.4 0.286 0.161 0.7922 0.67 0.383 1.17 -0.471 0.289 0.103 0.988 0.624 0.354 1.1 -0.342 0.283 0.227 0.6445 0.711 0.408 1.24 PRS_PLINK_0.001 FALSE 794 Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc) Both 28 270 17 symptoms purple 270, 28 68, 6 67, 5 67, 7 68, 10 0.86 0.694 0.215 0.6669 2.36 0.606 9.22 -0.033 0.574 0.954 0.02037 0.968 0.314 2.98 0.113 0.565 0.842 0.07472 1.12 0.37 3.39 0.53 0.514 0.302 0.5202 1.7 0.621 4.65 PRS_PLINK_0.001 TRUE 797 Shock Both 22 310 17 symptoms purple 310, 22 78, 4 77, 2 77, 8 78, 8 1.33 0.845 0.114 0.9414 3.8 0.724 19.9 -0.537 0.71 0.449 0.348 0.584 0.145 2.35 0.588 0.594 0.322 0.4917 1.8 0.562 5.77 0.528 0.616 0.392 0.4067 1.69 0.506 5.67 PRS_PLINK_0.001 TRUE 797.1 Cardiogenic shock Both 16 212 17 symptoms purple 212, 16 53, 3 53, 2 53, 5 53, 6 0.967 0.94 0.303 0.5184 2.63 0.417 16.6 -0.347 0.76 0.648 0.1885 0.707 0.159 3.14 0.377 0.665 0.571 0.2437 1.46 0.396 5.37 0.364 0.701 0.604 0.2193 1.44 0.364 5.68 PRS_PLINK_0.001 TRUE 798 Malaise and fatigue Both 502 7219 17 symptoms purple 7219, 502 1805, 114 1805, 145 1804, 123 1805, 120 0.0377 0.0349 0.28 0.5523 1.04 0.97 1.11 0.233 0.129 0.0704 1.152 1.26 0.981 1.63 0.0634 0.134 0.635 0.1975 1.07 0.82 1.38 0.0428 0.134 0.75 0.125 1.04 0.802 1.36 PRS_PLINK_0.001 FALSE 798.1 Chronic fatigue syndrome Both 97 1265 17 symptoms purple 1265, 97 317, 17 316, 34 316, 20 316, 26 0.0163 0.0866 0.85 0.07033 1.02 0.858 1.2 0.683 0.299 0.0225 1.647 1.98 1.1 3.56 0.147 0.33 0.654 0.1841 1.16 0.607 2.21 0.454 0.314 0.149 0.8278 1.57 0.85 2.92 PRS_PLINK_0.001 FALSE 800 Fracture of lower limb Both 1277 14620 18 injuries & poisonings gray50 14620, 1277 3655, 330 3655, 295 3655, 338 3655, 314 -0.0916 0.0525 0.0809 1.092 0.912 0.823 1.01 -0.108 0.0833 0.193 0.7145 0.897 0.762 1.06 0.0246 0.0807 0.761 0.1187 1.02 0.875 1.2 -0.0491 0.0821 0.55 0.2596 0.952 0.811 1.12 PRS_PLINK_0.001 FALSE 800.1 Fracture of neck of femur Both 295 3499 18 injuries & poisonings gray50 3499, 295 875, 80 875, 59 874, 76 875, 80 -0.0505 0.0693 0.466 0.3315 0.951 0.83 1.09 -0.297 0.176 0.092 1.036 0.743 0.526 1.05 -0.0512 0.166 0.757 0.1208 0.95 0.687 1.31 -0.00543 0.164 0.974 0.01162 0.995 0.721 1.37 PRS_PLINK_0.001 FALSE 800.2 Fracture of unspecified part of femur Both 19 330 18 injuries & poisonings gray50 330, 19 83, 3 82, 6 82, 5 83, 5 0.487 0.754 0.518 0.2855 1.63 0.371 7.14 0.597 0.676 0.378 0.4231 1.82 0.483 6.84 0.339 0.632 0.591 0.2281 1.4 0.407 4.85 0.39 0.661 0.555 0.256 1.48 0.405 5.39 PRS_PLINK_0.001 TRUE 800.3 Fracture of tibia and fibula Both 406 4638 18 injuries & poisonings gray50 4638, 406 1160, 100 1159, 88 1159, 120 1160, 98 -0.00796 0.0654 0.903 0.04425 0.992 0.873 1.13 -0.117 0.151 0.438 0.3587 0.889 0.661 1.2 0.181 0.141 0.198 0.703 1.2 0.909 1.58 -0.0213 0.147 0.885 0.05317 0.979 0.734 1.31 PRS_PLINK_0.001 FALSE 800.4 Fracture of patella Both 139 1656 18 injuries & poisonings gray50 1656, 139 414, 34 414, 34 414, 46 414, 25 -0.00206 0.0927 0.982 0.007774 0.998 0.832 1.2 0.0191 0.248 0.939 0.02754 1.02 0.627 1.66 0.29 0.234 0.214 0.6688 1.34 0.845 2.11 -0.24 0.268 0.37 0.4323 0.786 0.465 1.33 PRS_PLINK_0.001 FALSE 801 Fracture of ankle and foot Both 427 4761 18 injuries & poisonings gray50 4761, 427 1191, 94 1190, 128 1190, 104 1190, 101 0.0251 0.0515 0.626 0.2036 1.03 0.927 1.13 0.296 0.141 0.0364 1.439 1.34 1.02 1.77 0.0972 0.147 0.509 0.2933 1.1 0.826 1.47 0.083 0.149 0.576 0.2393 1.09 0.812 1.45 PRS_PLINK_0.001 FALSE 801.1 Fracture of foot Both 347 4028 18 injuries & poisonings gray50 4028, 347 1007, 76 1007, 108 1007, 84 1007, 79 -0.0573 0.103 0.579 0.2375 0.944 0.771 1.16 0.341 0.156 0.0287 1.543 1.41 1.04 1.91 0.103 0.163 0.528 0.2777 1.11 0.805 1.53 0.0432 0.166 0.794 0.1 1.04 0.755 1.44 PRS_PLINK_0.001 FALSE 802 Fracture of pelvis Both 127 1550 18 injuries & poisonings gray50 1550, 127 388, 36 387, 24 387, 36 388, 31 0.00549 0.0905 0.952 0.02155 1.01 0.842 1.2 -0.377 0.267 0.158 0.8019 0.686 0.407 1.16 -0.0328 0.243 0.893 0.04938 0.968 0.601 1.56 -0.127 0.251 0.613 0.2128 0.88 0.538 1.44 PRS_PLINK_0.001 FALSE 803 Fracture of upper limb Both 1511 17374 18 injuries & poisonings gray50 17374, 1511 4344, 368 4343, 378 4343, 390 4344, 375 -0.0401 0.0391 0.306 0.5147 0.961 0.89 1.04 0.0279 0.0762 0.714 0.1461 1.03 0.886 1.19 0.0545 0.0757 0.471 0.3267 1.06 0.91 1.22 0.0167 0.0764 0.827 0.08255 1.02 0.875 1.18 PRS_PLINK_0.001 FALSE 803.1 Fracture of humerus Both 264 3506 18 injuries & poisonings gray50 3506, 264 877, 74 876, 52 876, 73 877, 65 -0.0156 0.0866 0.857 0.06695 0.985 0.831 1.17 -0.374 0.185 0.0437 1.359 0.688 0.478 0.99 0.00761 0.17 0.964 0.01573 1.01 0.721 1.41 -0.136 0.175 0.437 0.3592 0.873 0.619 1.23 PRS_PLINK_0.001 FALSE 803.2 Fracture of radius and ulna Both 946 10878 18 injuries & poisonings gray50 10878, 946 2719, 233 2719, 242 2719, 233 2720, 238 -0.0259 0.045 0.564 0.2484 0.974 0.892 1.06 0.0433 0.0956 0.65 0.1869 1.04 0.866 1.26 -0.00631 0.0963 0.948 0.0233 0.994 0.823 1.2 0.0198 0.0958 0.836 0.07781 1.02 0.845 1.23 PRS_PLINK_0.001 FALSE 803.3 Fracture of clavicle or scapula Both 309 3307 18 injuries & poisonings gray50 3307, 309 827, 75 827, 85 826, 76 827, 73 -0.0126 0.0935 0.893 0.04927 0.987 0.822 1.19 0.136 0.165 0.408 0.3896 1.15 0.83 1.58 0.018 0.169 0.915 0.03861 1.02 0.731 1.42 -0.0489 0.171 0.775 0.1109 0.952 0.681 1.33 PRS_PLINK_0.001 FALSE 804 Fracture of hand or wrist Both 631 7134 18 injuries & poisonings gray50 7134, 631 1784, 134 1783, 173 1783, 162 1784, 162 0.0157 0.0307 0.609 0.2152 1.02 0.956 1.08 0.26 0.119 0.0292 1.535 1.3 1.03 1.64 0.187 0.121 0.123 0.9102 1.21 0.951 1.53 0.191 0.121 0.114 0.9419 1.21 0.955 1.53 PRS_PLINK_0.001 FALSE 805 Fracture of vertebral column without mention of spinal cord injury Both 217 2986 18 injuries & poisonings gray50 2986, 217 747, 59 746, 50 746, 52 747, 56 -0.0106 0.0625 0.865 0.06302 0.989 0.875 1.12 -0.132 0.197 0.503 0.298 0.876 0.596 1.29 -0.1 0.195 0.608 0.2164 0.905 0.617 1.33 -0.049 0.191 0.798 0.09823 0.952 0.655 1.38 PRS_PLINK_0.001 FALSE 807 Fracture of ribs Both 147 1642 18 injuries & poisonings gray50 1642, 147 411, 36 410, 34 410, 42 411, 35 0.00501 0.0709 0.944 0.0252 1.01 0.875 1.15 -0.0282 0.245 0.909 0.04165 0.972 0.601 1.57 0.137 0.234 0.559 0.2524 1.15 0.725 1.81 -0.0267 0.244 0.913 0.0396 0.974 0.604 1.57 PRS_PLINK_0.001 FALSE 809 Fracture of unspecified bones Both 206 2802 18 injuries & poisonings gray50 2802, 206 701, 51 700, 45 700, 58 701, 52 0.00407 0.0633 0.949 0.02287 1 0.887 1.14 -0.116 0.209 0.579 0.2374 0.891 0.592 1.34 0.128 0.197 0.515 0.2883 1.14 0.773 1.67 0.0343 0.202 0.865 0.06298 1.03 0.697 1.54 PRS_PLINK_0.001 FALSE 817 Concussion Both 43 534 18 injuries & poisonings gray50 534, 43 134, 12 133, 15 133, 6 134, 10 -0.581 0.548 0.289 0.5395 0.559 0.191 1.64 0.182 0.391 0.641 0.193 1.2 0.558 2.58 -0.799 0.483 0.098 1.009 0.45 0.174 1.16 -0.25 0.446 0.575 0.2401 0.779 0.325 1.87 PRS_PLINK_0.001 TRUE 818 Intracranial hemorrhage (injury) Both 86 1045 18 injuries & poisonings gray50 1045, 86 262, 25 261, 20 261, 20 261, 21 0.0608 0.124 0.623 0.2053 1.06 0.834 1.35 -0.2 0.306 0.513 0.2898 0.819 0.449 1.49 -0.22 0.305 0.471 0.327 0.802 0.441 1.46 -0.14 0.302 0.642 0.1923 0.869 0.481 1.57 PRS_PLINK_0.001 FALSE 819 Skull and face fracture and other intercranial injury Both 470 6208 18 injuries & poisonings gray50 6208, 470 1552, 120 1552, 122 1552, 115 1552, 113 -0.0449 0.0797 0.573 0.2417 0.956 0.818 1.12 0.0176 0.133 0.895 0.04831 1.02 0.784 1.32 -0.0455 0.135 0.735 0.1335 0.956 0.734 1.24 -0.062 0.136 0.647 0.1889 0.94 0.721 1.23 PRS_PLINK_0.001 FALSE 823 Torus fracture Both 335 3607 18 injuries & poisonings gray50 3607, 335 902, 76 902, 77 901, 105 902, 77 0.0113 0.0698 0.871 0.05981 1.01 0.882 1.16 0.0126 0.167 0.94 0.02685 1.01 0.729 1.41 0.309 0.157 0.0488 1.311 1.36 1 1.85 -0.00201 0.167 0.99 0.004184 0.998 0.719 1.38 PRS_PLINK_0.001 FALSE 830 Dislocation Both 405 4496 18 injuries & poisonings gray50 4496, 405 1124, 94 1124, 108 1124, 100 1124, 103 -0.00694 0.0628 0.912 0.04005 0.993 0.878 1.12 0.138 0.146 0.345 0.462 1.15 0.862 1.53 0.0709 0.149 0.634 0.198 1.07 0.802 1.44 0.111 0.148 0.455 0.3423 1.12 0.836 1.49 PRS_PLINK_0.001 FALSE 835 Internal derangement of knee Both 3123 33079 18 injuries & poisonings gray50 33079, 3123 8270, 781 8270, 772 8269, 761 8270, 809 0.0146 0.016 0.361 0.443 1.01 0.983 1.05 -0.0111 0.053 0.835 0.07839 0.989 0.891 1.1 -0.0271 0.0532 0.61 0.2146 0.973 0.877 1.08 0.0353 0.0525 0.501 0.3 1.04 0.935 1.15 PRS_PLINK_0.001 FALSE 836 Traumatic arthropathy Both 74 1162 18 injuries & poisonings gray50 1162, 74 291, 18 290, 15 290, 20 291, 21 0.0388 0.0863 0.653 0.1852 1.04 0.878 1.23 -0.154 0.343 0.654 0.1846 0.857 0.437 1.68 0.0888 0.324 0.784 0.1058 1.09 0.58 2.06 0.159 0.32 0.618 0.2087 1.17 0.626 2.2 PRS_PLINK_0.001 FALSE 840 Sprains and strains Both 88 993 18 injuries & poisonings gray50 993, 88 249, 21 248, 26 248, 20 248, 21 0.0149 0.0851 0.861 0.06481 1.01 0.859 1.2 0.206 0.3 0.491 0.309 1.23 0.683 2.21 -0.0287 0.314 0.927 0.03285 0.972 0.525 1.8 0.0249 0.314 0.937 0.02841 1.03 0.554 1.9 PRS_PLINK_0.001 FALSE 850 Hemorrhage or hematoma complicating a procedure Both 967 11348 18 injuries & poisonings gray50 11348, 967 2837, 243 2837, 224 2837, 249 2837, 251 0.00696 0.0273 0.799 0.09764 1.01 0.955 1.06 -0.0809 0.0961 0.4 0.3978 0.922 0.764 1.11 0.0224 0.0937 0.811 0.09077 1.02 0.851 1.23 0.0326 0.0936 0.727 0.1384 1.03 0.86 1.24 PRS_PLINK_0.001 FALSE 851 Complications of transplants and reattached limbs Both 28 358 18 injuries & poisonings gray50 358, 28 90, 8 89, 8 89, 7 90, 5 0.118 0.127 0.353 0.4524 1.13 0.877 1.44 0.17 0.509 0.739 0.1312 1.18 0.437 3.22 -0.0693 0.506 0.891 0.05011 0.933 0.346 2.51 -0.405 0.55 0.461 0.336 0.667 0.227 1.96 PRS_PLINK_0.001 TRUE 853 Complication of colostomy or enterostomy Both 78 1085 18 injuries & poisonings gray50 1085, 78 272, 21 271, 23 271, 16 271, 18 -0.371 0.386 0.337 0.4724 0.69 0.324 1.47 0.11 0.308 0.72 0.1427 1.12 0.61 2.04 -0.247 0.33 0.455 0.342 0.781 0.409 1.49 -0.166 0.322 0.605 0.218 0.847 0.451 1.59 PRS_PLINK_0.001 FALSE 854 Complications of cardiac/vascular device, implant, and graft Both 291 3797 18 injuries & poisonings gray50 3797, 291 950, 65 949, 73 949, 80 949, 73 -0.01 0.0576 0.862 0.06458 0.99 0.884 1.11 0.124 0.175 0.477 0.3213 1.13 0.804 1.6 0.208 0.172 0.225 0.6476 1.23 0.88 1.72 0.141 0.175 0.422 0.3751 1.15 0.817 1.62 PRS_PLINK_0.001 FALSE 857 Mechanical complication of unspecified genitourinary device, implant, and graft Both 208 2696 18 injuries & poisonings gray50 2696, 208 674, 56 674, 57 674, 44 674, 51 0.0771 0.0363 0.0337 1.473 1.08 1.01 1.16 -0.00727 0.194 0.97 0.01319 0.993 0.679 1.45 -0.222 0.207 0.283 0.5476 0.801 0.534 1.2 -0.11 0.199 0.578 0.2377 0.896 0.607 1.32 PRS_PLINK_0.001 FALSE 858 Complication of internal orthopedic device Both 572 6459 18 injuries & poisonings gray50 6459, 572 1615, 138 1615, 125 1614, 135 1615, 174 0.0196 0.035 0.575 0.2407 1.02 0.952 1.09 -0.0977 0.128 0.445 0.3518 0.907 0.706 1.17 -0.0184 0.125 0.883 0.05387 0.982 0.768 1.26 0.23 0.119 0.0526 1.279 1.26 0.997 1.59 PRS_PLINK_0.001 FALSE 859 Complication due to other implant and internal device Both 578 6888 18 injuries & poisonings gray50 6888, 578 1722, 129 1722, 143 1722, 139 1722, 167 0.0196 0.0359 0.585 0.2329 1.02 0.951 1.09 0.0958 0.126 0.446 0.3504 1.1 0.86 1.41 0.0786 0.127 0.534 0.2723 1.08 0.844 1.39 0.257 0.122 0.0348 1.459 1.29 1.02 1.64 PRS_PLINK_0.001 FALSE 860 Bone marrow or stem cell transplant Both 6 168 2 neoplasms darkcyan 168, 6 42, 1 42, 1 42, 2 42, 2 0.498 0.753 0.508 0.2939 1.65 0.376 7.19 0.0367 0.961 0.97 0.01342 1.04 0.158 6.83 -0.443 1.14 0.698 0.1562 0.642 0.0684 6.02 0.375 0.856 0.662 0.1794 1.45 0.272 7.79 PRS_PLINK_0.001 TRUE 870 Open wounds of head; neck; and trunk Both 532 7445 18 injuries & poisonings gray50 7445, 532 1862, 136 1861, 130 1861, 135 1861, 131 0.0301 0.036 0.403 0.3947 1.03 0.96 1.11 -0.0429 0.126 0.734 0.1341 0.958 0.748 1.23 0.00485 0.125 0.969 0.01361 1 0.786 1.28 -0.0373 0.126 0.767 0.1151 0.963 0.752 1.23 PRS_PLINK_0.001 FALSE 870.1 Open wound or laceration of eye or eyelid Both 46 577 18 injuries & poisonings gray50 577, 46 145, 14 144, 14 144, 13 144, 5 -1.05 0.49 0.0326 1.487 0.351 0.134 0.917 -0.0104 0.388 0.979 0.009373 0.99 0.462 2.12 -0.103 0.386 0.789 0.1027 0.902 0.424 1.92 -1.06 0.499 0.0332 1.479 0.345 0.13 0.919 PRS_PLINK_0.001 TRUE 870.2 Open wound of ear Both 28 382 18 injuries & poisonings gray50 382, 28 96, 5 95, 9 95, 6 96, 8 0.072 0.12 0.55 0.2598 1.07 0.849 1.36 0.478 0.533 0.371 0.4311 1.61 0.567 4.59 0.288 0.559 0.606 0.2174 1.33 0.446 3.99 0.448 0.564 0.427 0.3695 1.57 0.518 4.73 PRS_PLINK_0.001 TRUE 870.3 Other open wound of head and face Both 433 6160 18 injuries & poisonings gray50 6160, 433 1540, 116 1540, 94 1540, 114 1540, 109 0.0537 0.0376 0.154 0.8134 1.06 0.98 1.14 -0.208 0.143 0.144 0.8407 0.812 0.614 1.07 -0.00553 0.136 0.968 0.01431 0.994 0.762 1.3 -0.0564 0.137 0.682 0.1665 0.945 0.722 1.24 PRS_PLINK_0.001 FALSE 870.4 Open wound of nose and sinus Both 34 453 18 injuries & poisonings gray50 453, 34 114, 10 113, 11 113, 5 113, 8 -0.598 0.612 0.328 0.4835 0.55 0.166 1.82 0.183 0.439 0.676 0.17 1.2 0.508 2.84 -0.535 0.52 0.303 0.5185 0.586 0.212 1.62 0.0931 0.485 0.848 0.07175 1.1 0.424 2.84 PRS_PLINK_0.001 TRUE 870.6 Open wound of neck Both 13 155 18 injuries & poisonings gray50 155, 13 39, 4 39, 2 38, 3 39, 4 0.0559 0.126 0.658 0.182 1.06 0.826 1.35 -0.714 0.773 0.356 0.449 0.49 0.108 2.23 -0.468 0.745 0.53 0.2759 0.626 0.146 2.7 -0.314 0.689 0.649 0.1879 0.731 0.19 2.82 PRS_PLINK_0.001 TRUE 871 Open wounds of extremities Both 688 8821 18 injuries & poisonings gray50 8821, 688 2206, 157 2205, 180 2205, 179 2205, 172 0.033 0.0331 0.319 0.4964 1.03 0.969 1.1 0.141 0.113 0.213 0.672 1.15 0.923 1.44 0.133 0.113 0.24 0.6207 1.14 0.915 1.43 0.0938 0.114 0.41 0.387 1.1 0.879 1.37 PRS_PLINK_0.001 FALSE 871.1 Open wound of hand except finger(s) Both 2 103 18 injuries & poisonings gray50 103, 2 26, 0 26, 0 25, 0 26, 2 2.27 2.24 0.31 0.5085 9.72 0.12 785 0.391 1.18 0.74 0.1307 1.48 0.147 14.9 0.158 1.15 0.89 0.05047 1.17 0.124 11.1 0.507 1.23 0.681 0.167 1.66 0.149 18.5 PRS_PLINK_0.001 TRUE 871.2 Open wound of finger(s) Both 8 169 18 injuries & poisonings gray50 169, 8 43, 0 42, 3 42, 3 42, 2 1 1.03 0.33 0.4809 2.73 0.361 20.6 1.61 1.18 0.173 0.7621 5 0.494 50.7 1.58 1.16 0.174 0.7606 4.87 0.498 47.7 1.25 1.08 0.248 0.6062 3.5 0.418 29.3 PRS_PLINK_0.001 TRUE 871.3 Open wound of foot except toe(s) alone Both 27 410 18 injuries & poisonings gray50 410, 27 103, 9 102, 7 102, 3 103, 8 -0.649 0.625 0.299 0.5243 0.522 0.153 1.78 -0.262 0.5 0.6 0.2216 0.77 0.289 2.05 -1.06 0.598 0.0756 1.122 0.345 0.107 1.12 -0.0747 0.47 0.874 0.05862 0.928 0.369 2.33 PRS_PLINK_0.001 TRUE 872 Traumatic amputation Both 81 1020 18 injuries & poisonings gray50 1020, 81 255, 17 255, 24 255, 23 255, 17 0.0304 0.0834 0.715 0.1455 1.03 0.875 1.21 0.318 0.32 0.321 0.4941 1.37 0.734 2.57 0.263 0.321 0.412 0.3848 1.3 0.694 2.44 -0.0158 0.343 0.963 0.01624 0.984 0.502 1.93 PRS_PLINK_0.001 FALSE 873 Broken tooth Both 48 465 18 injuries & poisonings gray50 465, 48 117, 12 116, 10 116, 13 116, 13 0.078 0.116 0.503 0.2988 1.08 0.861 1.36 0.0598 0.438 0.891 0.04995 1.06 0.45 2.51 0.164 0.412 0.69 0.1611 1.18 0.525 2.64 0.151 0.411 0.714 0.1465 1.16 0.519 2.6 PRS_PLINK_0.001 TRUE 874 Complication of amputation stump Both 23 365 18 injuries & poisonings gray50 365, 23 92, 7 91, 5 91, 8 91, 3 0.183 0.117 0.116 0.9348 1.2 0.956 1.51 -0.219 0.547 0.689 0.162 0.803 0.275 2.34 0.16 0.514 0.756 0.1215 1.17 0.429 3.21 -0.79 0.613 0.198 0.7037 0.454 0.136 1.51 PRS_PLINK_0.001 TRUE 905 Late effects of musculoskeletal and connective tissue injuries Both 33 337 18 injuries & poisonings gray50 337, 33 85, 7 84, 9 84, 5 84, 12 0.0387 0.0845 0.647 0.189 1.04 0.881 1.23 0.561 0.545 0.303 0.5181 1.75 0.602 5.09 -0.136 0.562 0.808 0.09257 0.872 0.29 2.62 0.642 0.495 0.194 0.7119 1.9 0.721 5.01 PRS_PLINK_0.001 TRUE 907 Injuries to the nervous system Both 250 2894 18 injuries & poisonings gray50 2894, 250 724, 64 723, 63 723, 63 724, 60 -0.0131 0.0707 0.853 0.06914 0.987 0.859 1.13 -0.0258 0.183 0.888 0.05149 0.975 0.68 1.4 -0.0021 0.184 0.991 0.003979 0.998 0.696 1.43 -0.0865 0.185 0.641 0.1932 0.917 0.638 1.32 PRS_PLINK_0.001 FALSE 915 Superficial injury without mention of infection Both 651 8811 18 injuries & poisonings gray50 8811, 651 2203, 157 2203, 175 2202, 166 2203, 153 -0.085 0.0745 0.254 0.5951 0.919 0.794 1.06 0.109 0.114 0.337 0.4729 1.12 0.893 1.39 0.0527 0.115 0.646 0.1896 1.05 0.842 1.32 -0.0184 0.117 0.875 0.05785 0.982 0.781 1.23 PRS_PLINK_0.001 FALSE 916 Contusion Both 235 2936 18 injuries & poisonings gray50 2936, 235 734, 51 734, 58 734, 74 734, 52 0.0439 0.0396 0.268 0.572 1.04 0.967 1.13 0.134 0.197 0.496 0.3048 1.14 0.777 1.68 0.374 0.188 0.0462 1.335 1.45 1.01 2.1 0.0344 0.202 0.865 0.0629 1.03 0.696 1.54 PRS_PLINK_0.001 FALSE 930 Allergic reaction to food Both 28 393 18 injuries & poisonings gray50 393, 28 99, 8 98, 5 98, 7 98, 8 0.0926 0.644 0.886 0.05278 1.1 0.311 3.87 -0.311 0.531 0.557 0.2538 0.733 0.259 2.07 -0.00158 0.509 0.998 0.001074 0.998 0.368 2.71 0.0421 0.497 0.932 0.0304 1.04 0.394 2.76 PRS_PLINK_0.001 TRUE 938 Dermatitis due to solar radiation Both 66 795 18 injuries & poisonings gray50 795, 66 199, 22 199, 19 198, 8 199, 17 0.121 0.0749 0.107 0.9691 1.13 0.974 1.31 -0.212 0.322 0.511 0.2919 0.809 0.43 1.52 -1.08 0.408 0.00807 2.093 0.339 0.153 0.755 -0.289 0.332 0.384 0.4157 0.749 0.391 1.44 PRS_PLINK_0.001 FALSE 938.2 Chronic dermatitis due to solar radiation Both 41 513 18 injuries & poisonings gray50 513, 41 129, 14 128, 13 128, 2 128, 12 -0.432 0.507 0.395 0.4032 0.65 0.24 1.76 -0.137 0.398 0.73 0.1369 0.872 0.4 1.9 -1.81 0.651 0.00544 2.264 0.164 0.0456 0.586 -0.14 0.406 0.729 0.1371 0.869 0.392 1.92 PRS_PLINK_0.001 TRUE 939 Atopic/contact dermatitis due to other or unspecified Both 378 4371 13 dermatologic firebrick 4371, 378 1093, 96 1093, 78 1092, 106 1093, 98 0.0504 0.0301 0.094 1.027 1.05 0.991 1.12 -0.21 0.157 0.181 0.7414 0.811 0.596 1.1 0.109 0.146 0.457 0.3405 1.12 0.837 1.49 0.0304 0.149 0.839 0.07631 1.03 0.769 1.38 PRS_PLINK_0.001 FALSE 941 Adverse reaction to serum or vaccine Both 45 467 18 injuries & poisonings gray50 467, 45 117, 11 117, 9 116, 10 117, 15 0.0312 0.0892 0.727 0.1387 1.03 0.866 1.23 -0.265 0.445 0.551 0.259 0.767 0.321 1.83 -0.165 0.446 0.711 0.148 0.848 0.354 2.03 0.376 0.414 0.364 0.4389 1.46 0.647 3.28 PRS_PLINK_0.001 TRUE 942 Infusion and transfusion reaction Both 18 218 18 injuries & poisonings gray50 218, 18 55, 5 54, 4 54, 3 55, 6 0.931 0.495 0.0602 1.221 2.54 0.961 6.7 -0.257 0.7 0.714 0.1464 0.773 0.196 3.05 -0.425 0.676 0.529 0.2762 0.654 0.174 2.46 0.226 0.616 0.714 0.1463 1.25 0.375 4.19 PRS_PLINK_0.001 TRUE 946 Anaphylactic shock NOS Both 96 1193 18 injuries & poisonings gray50 1193, 96 299, 19 298, 29 298, 17 298, 31 0.0169 0.0866 0.845 0.07316 1.02 0.858 1.21 0.412 0.298 0.167 0.7763 1.51 0.841 2.71 -0.0799 0.331 0.809 0.09193 0.923 0.483 1.77 0.474 0.295 0.107 0.9689 1.61 0.902 2.86 PRS_PLINK_0.001 FALSE 947 Urticaria Both 65 791 18 injuries & poisonings gray50 791, 65 198, 12 198, 20 197, 14 198, 19 0.0399 0.0649 0.538 0.269 1.04 0.916 1.18 0.457 0.366 0.211 0.6753 1.58 0.771 3.24 0.122 0.392 0.755 0.1221 1.13 0.524 2.44 0.377 0.369 0.306 0.5137 1.46 0.708 3.01 PRS_PLINK_0.001 FALSE 949 Allergies, other Both 66 891 18 injuries & poisonings gray50 891, 66 223, 16 223, 15 222, 16 223, 19 0.0114 0.0814 0.888 0.05154 1.01 0.862 1.19 -0.058 0.354 0.87 0.06055 0.944 0.471 1.89 0.031 0.353 0.93 0.03149 1.03 0.516 2.06 0.151 0.339 0.655 0.1834 1.16 0.599 2.26 PRS_PLINK_0.001 FALSE 952 Spinal cord injury without evidence of spinal bone injury Both 76 950 18 injuries & poisonings gray50 950, 76 238, 24 237, 15 237, 20 238, 17 0.0112 0.0701 0.872 0.05924 1.01 0.882 1.16 -0.45 0.333 0.176 0.7536 0.637 0.332 1.22 -0.182 0.313 0.56 0.2519 0.833 0.452 1.54 -0.289 0.322 0.37 0.4317 0.749 0.399 1.41 PRS_PLINK_0.001 FALSE 957 Injury to other and unspecified nerves Both 37 528 18 injuries & poisonings gray50 528, 37 132, 6 132, 13 132, 11 132, 7 0.0269 0.0708 0.704 0.1525 1.03 0.894 1.18 0.771 0.473 0.103 0.9862 2.16 0.855 5.46 0.799 0.516 0.122 0.9146 2.22 0.808 6.11 0.268 0.517 0.604 0.2191 1.31 0.475 3.6 PRS_PLINK_0.001 TRUE 958 Certain early complications of trauma or procedure Both 71 1028 18 injuries & poisonings gray50 1028, 71 257, 18 257, 18 257, 24 257, 11 -0.294 0.409 0.473 0.3253 0.745 0.334 1.66 0.0753 0.337 0.823 0.0845 1.08 0.557 2.09 0.281 0.316 0.375 0.4261 1.32 0.712 2.46 -0.46 0.373 0.217 0.6636 0.631 0.304 1.31 PRS_PLINK_0.001 FALSE 958.1 Postoperative shock Both 5 118 18 injuries & poisonings gray50 118, 5 30, 1 29, 0 29, 4 30, 0 -0.104 1.19 0.93 0.03132 0.901 0.0871 9.32 -1.16 1.22 0.344 0.4633 0.314 0.0286 3.45 1.33 0.951 0.162 0.791 3.78 0.587 24.4 -0.149 1.22 0.903 0.04426 0.862 0.0786 9.45 PRS_PLINK_0.001 TRUE 958.2 Traumatic and surgical subcutaneous emphysema Both 13 137 18 injuries & poisonings gray50 137, 13 35, 5 34, 4 34, 2 34, 2 -0.798 1.01 0.431 0.3654 0.45 0.0617 3.28 -0.103 0.688 0.881 0.05515 0.902 0.234 3.47 -0.873 0.773 0.259 0.5869 0.418 0.0917 1.9 -0.749 0.795 0.346 0.4604 0.473 0.0995 2.25 PRS_PLINK_0.001 TRUE 960 Poisoning by antibiotics Both 3411 39145 18 injuries & poisonings gray50 39145, 3411 9786, 881 9786, 849 9786, 825 9786, 856 0.0287 0.0128 0.0252 1.599 1.03 1 1.06 -0.0369 0.0502 0.462 0.3356 0.964 0.874 1.06 -0.0672 0.0505 0.183 0.7373 0.935 0.847 1.03 -0.0304 0.0501 0.544 0.2648 0.97 0.879 1.07 PRS_PLINK_0.001 FALSE 960.2 Allergy/adverse effect of penicillin Both 2962 34307 18 injuries & poisonings gray50 34307, 2962 8576, 771 8577, 752 8576, 701 8577, 738 0.0271 0.0142 0.0554 1.256 1.03 0.999 1.06 -0.0251 0.0535 0.639 0.1946 0.975 0.878 1.08 -0.0976 0.0544 0.0725 1.14 0.907 0.815 1.01 -0.0463 0.0537 0.389 0.4106 0.955 0.859 1.06 PRS_PLINK_0.001 FALSE 961 Poisoning by other anti-infectives Both 79 849 18 injuries & poisonings gray50 849, 79 213, 16 212, 22 212, 20 212, 21 0.0379 0.0921 0.681 0.1671 1.04 0.867 1.24 0.365 0.334 0.274 0.5618 1.44 0.748 2.77 0.245 0.338 0.469 0.3286 1.28 0.658 2.48 0.248 0.335 0.46 0.3376 1.28 0.664 2.47 PRS_PLINK_0.001 FALSE 961.1 Poisoning/allergy of sulfonamides Both 163 1885 18 injuries & poisonings gray50 1885, 163 472, 45 471, 36 471, 43 471, 39 -0.0145 0.0746 0.846 0.07285 0.986 0.852 1.14 -0.205 0.23 0.372 0.4297 0.814 0.519 1.28 -0.0559 0.22 0.799 0.09733 0.946 0.615 1.45 -0.138 0.225 0.54 0.2679 0.871 0.561 1.35 PRS_PLINK_0.001 FALSE 962 Poisoning by hormones and synthetic substitutes Both 51 768 18 injuries & poisonings gray50 768, 51 192, 10 192, 11 192, 15 192, 15 0.0461 0.0811 0.57 0.2439 1.05 0.893 1.23 0.0676 0.424 0.873 0.05882 1.07 0.466 2.46 0.322 0.398 0.419 0.3775 1.38 0.632 3.01 0.344 0.397 0.386 0.4132 1.41 0.648 3.07 PRS_PLINK_0.001 FALSE 962.3 Hormones and synthetic substitutes causing adverse effects in therapeutic use Both 50 759 18 injuries & poisonings gray50 759, 50 190, 9 190, 13 189, 14 190, 14 0.0409 0.0846 0.629 0.2013 1.04 0.883 1.23 0.319 0.423 0.451 0.346 1.38 0.6 3.15 0.335 0.412 0.416 0.3806 1.4 0.623 3.14 0.367 0.414 0.376 0.4248 1.44 0.641 3.25 PRS_PLINK_0.001 TRUE 963 Poisoning by primarily systemic agents Both 36 473 18 injuries & poisonings gray50 473, 36 119, 11 118, 11 118, 6 118, 8 0.128 0.0756 0.089 1.05 1.14 0.981 1.32 0.0766 0.431 0.859 0.06607 1.08 0.464 2.51 -0.603 0.487 0.216 0.6661 0.547 0.211 1.42 -0.175 0.455 0.7 0.1546 0.839 0.344 2.05 PRS_PLINK_0.001 TRUE 964 Poisoning by agents primarily affecting blood constituents Both 53 557 18 injuries & poisonings gray50 557, 53 140, 16 139, 13 139, 11 139, 13 -0.582 0.471 0.217 0.6628 0.559 0.222 1.41 -0.175 0.377 0.642 0.1928 0.839 0.401 1.76 -0.381 0.397 0.337 0.4718 0.683 0.313 1.49 -0.231 0.384 0.546 0.2625 0.793 0.374 1.68 PRS_PLINK_0.001 FALSE 964.1 Anticoagulants causing adverse effects Both 52 542 18 injuries & poisonings gray50 542, 52 136, 15 135, 13 135, 11 136, 13 -0.471 0.472 0.319 0.4963 0.625 0.247 1.58 -0.138 0.382 0.717 0.1442 0.871 0.412 1.84 -0.328 0.4 0.413 0.3843 0.721 0.329 1.58 -0.181 0.389 0.642 0.1924 0.835 0.39 1.79 PRS_PLINK_0.001 FALSE 965 Poisoning by analgesics, antipyretics, and antirheumatics Both 997 12977 18 injuries & poisonings gray50 12977, 997 3245, 240 3244, 266 3244, 239 3244, 252 0.0354 0.0285 0.214 0.6705 1.04 0.98 1.1 0.107 0.0923 0.246 0.6084 1.11 0.929 1.33 0.00249 0.0947 0.979 0.00921 1 0.833 1.21 0.0427 0.0935 0.648 0.1887 1.04 0.869 1.25 PRS_PLINK_0.001 FALSE 965.1 Opiates and related narcotics causing adverse effects in therapeutic use Both 226 2465 18 injuries & poisonings gray50 2465, 226 617, 70 616, 56 616, 44 616, 56 -0.0182 0.0896 0.839 0.07632 0.982 0.824 1.17 -0.21 0.187 0.262 0.5821 0.811 0.562 1.17 -0.456 0.199 0.0219 1.659 0.634 0.429 0.936 -0.22 0.186 0.238 0.6238 0.803 0.557 1.16 PRS_PLINK_0.001 FALSE 965.2 Antirheumatics causing adverse effects in therapeutic use Both 59 1089 18 injuries & poisonings gray50 1089, 59 273, 15 272, 18 272, 11 272, 15 0.0763 0.125 0.542 0.2663 1.08 0.845 1.38 0.28 0.346 0.418 0.3785 1.32 0.672 2.6 -0.264 0.381 0.488 0.3118 0.768 0.364 1.62 -0.102 0.363 0.78 0.1081 0.903 0.443 1.84 PRS_PLINK_0.001 FALSE 965.3 Salicylates causing adverse effects in therapeutic use Both 51 862 18 injuries & poisonings gray50 862, 51 216, 7 215, 16 215, 18 216, 10 0.0492 0.0853 0.564 0.2488 1.05 0.889 1.24 0.806 0.437 0.0648 1.189 2.24 0.952 5.27 0.881 0.425 0.0384 1.416 2.41 1.05 5.55 0.486 0.47 0.301 0.5215 1.63 0.647 4.08 PRS_PLINK_0.001 FALSE 966 Poisoning by anticonvulsants and anti-Parkinsonism drugs Both 72 1104 18 injuries & poisonings gray50 1104, 72 276, 19 276, 17 276, 14 276, 22 0.151 0.0725 0.0379 1.422 1.16 1.01 1.34 -0.104 0.334 0.756 0.1216 0.901 0.468 1.73 -0.236 0.352 0.502 0.2997 0.789 0.396 1.57 0.156 0.317 0.622 0.2065 1.17 0.628 2.18 PRS_PLINK_0.001 FALSE 967 Adverse effects of sedatives or other central nervous system depressants and anesthetics Both 91 1219 18 injuries & poisonings gray50 1219, 91 305, 24 305, 18 304, 27 305, 22 0.0318 0.125 0.8 0.09713 1.03 0.808 1.32 -0.221 0.315 0.482 0.3169 0.801 0.432 1.49 0.134 0.286 0.639 0.1944 1.14 0.653 2 -0.0345 0.299 0.908 0.04187 0.966 0.538 1.74 PRS_PLINK_0.001 FALSE 969 Poisoning by psychotropic agents Both 239 4252 18 injuries & poisonings gray50 4252, 239 1063, 47 1063, 69 1063, 63 1063, 60 0.021 0.0636 0.741 0.1301 1.02 0.902 1.16 0.377 0.191 0.0483 1.316 1.46 1 2.12 0.306 0.195 0.117 0.9325 1.36 0.926 1.99 0.23 0.197 0.242 0.6162 1.26 0.856 1.85 PRS_PLINK_0.001 FALSE 971 Poisoning by drugs primarily affecting the autonomic nervous system Both 17 443 18 injuries & poisonings gray50 443, 17 111, 4 111, 4 110, 5 111, 4 0.127 0.118 0.283 0.5489 1.14 0.901 1.43 -0.0229 0.619 0.97 0.01303 0.977 0.291 3.29 0.0917 0.606 0.88 0.05569 1.1 0.334 3.59 0.0724 0.62 0.907 0.04235 1.08 0.319 3.62 PRS_PLINK_0.001 TRUE 972 Poisoning by agents primarily affecting the cardiovascular system Both 33 604 18 injuries & poisonings gray50 604, 33 151, 8 151, 5 151, 14 151, 6 0.0698 0.1 0.487 0.3123 1.07 0.881 1.31 -0.508 0.527 0.335 0.4749 0.602 0.214 1.69 0.592 0.433 0.171 0.7672 1.81 0.774 4.22 -0.318 0.51 0.533 0.2735 0.727 0.268 1.98 PRS_PLINK_0.001 TRUE 972.6 Antihypertensive agents causing adverse effects Both 9 157 18 injuries & poisonings gray50 157, 9 40, 1 39, 5 39, 3 39, 0 -0.753 1.07 0.482 0.3166 0.471 0.0577 3.85 0.778 0.874 0.374 0.4277 2.18 0.392 12.1 1.47 1.05 0.161 0.793 4.35 0.557 34 -1.58 1.26 0.21 0.677 0.205 0.0172 2.45 PRS_PLINK_0.001 TRUE 973 Poisoning by agents primarily affecting the gastrointestinal system Both 11 238 18 injuries & poisonings gray50 238, 11 60, 3 59, 4 59, 1 60, 3 0.269 0.664 0.685 0.1644 1.31 0.356 4.81 -0.949 0.863 0.272 0.5662 0.387 0.0713 2.1 0.109 0.734 0.882 0.05457 1.12 0.265 4.7 PRS_PLINK_0.001 TRUE 974 Poisoning by water, mineral, and uric acid metabolism drugs Both 11 176 18 injuries & poisonings gray50 176, 11 44, 4 44, 0 44, 4 44, 3 0.362 0.972 0.709 0.1491 1.44 0.214 9.66 -2.05 1.18 0.0808 1.093 0.128 0.0128 1.29 -0.0212 0.649 0.974 0.01144 0.979 0.274 3.49 -0.0819 0.727 0.91 0.04078 0.921 0.222 3.83 PRS_PLINK_0.001 TRUE 975 Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system Both 7 122 18 injuries & poisonings gray50 122, 7 31, 2 30, 1 30, 2 31, 2 0.279 0.663 0.674 0.1713 1.32 0.36 4.85 -0.166 0.935 0.859 0.06599 0.847 0.136 5.29 0.712 0.992 0.472 0.3256 2.04 0.292 14.2 0.455 1.05 0.663 0.1782 1.58 0.203 12.2 PRS_PLINK_0.001 TRUE 976 Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs Both 8 114 18 injuries & poisonings gray50 114, 8 29, 1 28, 4 28, 2 29, 1 1.63 0.97 0.0925 1.034 5.11 0.764 34.2 0.687 1.05 0.514 0.289 1.99 0.253 15.6 0.524 1.22 0.668 0.1753 1.69 0.154 18.5 PRS_PLINK_0.001 TRUE 977 Personal history of allergy to medicinal agents Both 48 483 18 injuries & poisonings gray50 483, 48 121, 14 121, 16 120, 8 121, 10 -0.00103 0.0876 0.991 0.004103 0.999 0.841 1.19 0.104 0.377 0.783 0.106 1.11 0.53 2.32 -0.606 0.439 0.167 0.7762 0.546 0.231 1.29 -0.291 0.416 0.484 0.3148 0.747 0.331 1.69 PRS_PLINK_0.001 TRUE 979 Adverse drug events and drug allergies Both 97 1517 18 injuries & poisonings gray50 1517, 97 380, 27 379, 27 379, 20 379, 23 0.0252 0.09 0.779 0.1084 1.03 0.86 1.22 -0.0259 0.275 0.925 0.03389 0.974 0.568 1.67 -0.251 0.296 0.396 0.4025 0.778 0.435 1.39 -0.165 0.285 0.564 0.2489 0.848 0.485 1.48 PRS_PLINK_0.001 FALSE 981 Toxic effect of (non-ethyl) alcohol and petroleum and other solvents Both 25 433 18 injuries & poisonings gray50 433, 25 109, 4 108, 7 108, 6 108, 8 0.74 0.656 0.259 0.5867 2.1 0.58 7.58 0.455 0.573 0.428 0.369 1.58 0.513 4.84 0.34 0.573 0.553 0.2574 1.4 0.457 4.32 0.699 0.575 0.224 0.6501 2.01 0.652 6.21 PRS_PLINK_0.001 TRUE 986 Toxic effect of carbon monoxide Both 7 128 18 injuries & poisonings gray50 128, 7 32, 0 32, 4 32, 0 32, 3 0.46 0.373 0.217 0.6639 1.58 0.763 3.29 2.56 1.53 0.0949 1.023 12.9 0.641 260 0.291 1.22 0.811 0.09097 1.34 0.123 14.5 0.514 1.26 0.683 0.1655 1.67 0.142 19.7 PRS_PLINK_0.001 TRUE 987 Toxic effect of other gases, fumes, or vapors Both 7 222 18 injuries & poisonings gray50 222, 7 56, 1 55, 1 55, 3 56, 2 -0.0196 1 0.984 0.006806 0.981 0.137 7.03 0.475 0.918 0.605 0.2185 1.61 0.266 9.73 -0.506 0.998 0.612 0.2132 0.603 0.0852 4.26 PRS_PLINK_0.001 TRUE 988 Toxic effect of noxious substances eaten as food Both 12 244 18 injuries & poisonings gray50 244, 12 61, 2 61, 0 61, 5 61, 5 -1.66 1.2 0.166 0.7788 0.189 0.0179 2 0.82 0.728 0.26 0.5844 2.27 0.545 9.46 0.828 0.718 0.249 0.6042 2.29 0.56 9.36 PRS_PLINK_0.001 TRUE 989 Toxic effect of other substances, chiefly nonmedicinal as to source Both 21 187 18 injuries & poisonings gray50 187, 21 47, 3 47, 9 46, 4 47, 5 0.513 0.862 0.551 0.2586 1.67 0.309 9.04 1.16 0.708 0.101 0.9939 3.19 0.796 12.8 0.368 0.735 0.617 0.2098 1.44 0.342 6.11 0.338 0.708 0.633 0.1984 1.4 0.35 5.62 PRS_PLINK_0.001 TRUE 990 Effects radiation NOS Both 539 6462 18 injuries & poisonings gray50 6462, 539 1616, 148 1615, 134 1615, 110 1616, 147 -0.0652 0.0795 0.412 0.3849 0.937 0.802 1.09 -0.0938 0.124 0.448 0.3485 0.91 0.714 1.16 -0.292 0.13 0.0249 1.603 0.747 0.579 0.964 -0.0114 0.121 0.925 0.03386 0.989 0.78 1.25 PRS_PLINK_0.001 FALSE 994 Sepsis and SIRS Both 478 6204 18 injuries & poisonings gray50 6204, 478 1551, 119 1551, 119 1551, 109 1551, 131 -0.0225 0.0672 0.738 0.1317 0.978 0.857 1.12 -0.00755 0.134 0.955 0.01997 0.992 0.763 1.29 -0.0995 0.137 0.467 0.3309 0.905 0.693 1.18 0.0911 0.131 0.487 0.3122 1.1 0.847 1.42 PRS_PLINK_0.001 FALSE 994.2 Sepsis Both 478 6204 18 injuries & poisonings gray50 6204, 478 1551, 119 1551, 119 1551, 109 1551, 131 -0.0225 0.0672 0.738 0.1317 0.978 0.857 1.12 -0.00755 0.134 0.955 0.01997 0.992 0.763 1.29 -0.0995 0.137 0.467 0.3309 0.905 0.693 1.18 0.0911 0.131 0.487 0.3122 1.1 0.847 1.42 PRS_PLINK_0.001 FALSE 1000 Burns Both 97 1276 18 injuries & poisonings gray50 1276, 97 319, 25 319, 19 319, 27 319, 26 -0.00553 0.0807 0.945 0.0244 0.994 0.849 1.16 -0.252 0.304 0.407 0.3908 0.777 0.429 1.41 0.0823 0.283 0.771 0.113 1.09 0.624 1.89 0.0114 0.285 0.968 0.01408 1.01 0.579 1.77 PRS_PLINK_0.001 FALSE 1001 Foreign body injury Both 215 2496 18 injuries & poisonings gray50 2496, 215 624, 74 624, 52 624, 43 624, 46 0.003 0.06 0.96 0.01767 1 0.892 1.13 -0.373 0.189 0.0482 1.317 0.689 0.476 0.997 -0.544 0.198 0.00596 2.225 0.58 0.394 0.855 -0.49 0.195 0.0118 1.927 0.613 0.418 0.897 PRS_PLINK_0.001 FALSE 1002 Symptoms concerning nutrition, metabolism, and development Both 892 11338 18 injuries & poisonings gray50 11338, 892 2835, 213 2834, 228 2834, 229 2835, 222 0.0342 0.0287 0.234 0.6312 1.03 0.978 1.09 0.0712 0.0987 0.471 0.3273 1.07 0.885 1.3 0.0726 0.0985 0.461 0.3362 1.08 0.887 1.3 0.0379 0.0992 0.702 0.1536 1.04 0.855 1.26 PRS_PLINK_0.001 FALSE 1004 Other signs and symptoms involving emotional state Both 32 650 18 injuries & poisonings gray50 650, 32 163, 9 162, 7 162, 6 163, 10 0.0962 0.103 0.349 0.4575 1.1 0.9 1.35 -0.229 0.477 0.631 0.1999 0.795 0.312 2.03 -0.337 0.487 0.489 0.3103 0.714 0.275 1.85 0.172 0.448 0.7 0.1547 1.19 0.494 2.86 PRS_PLINK_0.001 TRUE 1005 Other symptoms Both 230 3024 18 injuries & poisonings gray50 3024, 230 756, 59 756, 57 756, 58 756, 56 0.0792 0.0522 0.129 0.8887 1.08 0.977 1.2 -0.0457 0.19 0.81 0.09129 0.955 0.658 1.39 -0.0181 0.191 0.924 0.03423 0.982 0.676 1.43 -0.077 0.192 0.688 0.1622 0.926 0.636 1.35 PRS_PLINK_0.001 FALSE 1006 Crushing injury Both 42 532 18 injuries & poisonings gray50 532, 42 133, 9 133, 13 133, 12 133, 8 -0.78 0.532 0.143 0.8454 0.459 0.162 1.3 0.313 0.435 0.471 0.3273 1.37 0.584 3.21 0.305 0.435 0.483 0.3159 1.36 0.578 3.18 -0.0795 0.479 0.868 0.06138 0.924 0.361 2.36 PRS_PLINK_0.001 TRUE 1007 Injury to blood vessels Both 48 553 18 injuries & poisonings gray50 553, 48 139, 11 138, 6 138, 17 138, 14 0.0996 0.112 0.373 0.4281 1.1 0.887 1.38 -0.317 0.486 0.514 0.289 0.728 0.281 1.89 0.492 0.4 0.219 0.6599 1.64 0.747 3.58 0.28 0.417 0.502 0.2993 1.32 0.585 2.99 PRS_PLINK_0.001 TRUE 1008 Crushing or internal injury to organs Both 181 2129 18 injuries & poisonings gray50 2129, 181 533, 46 532, 42 532, 51 532, 42 -0.00342 0.0679 0.96 0.01778 0.997 0.872 1.14 -0.0944 0.219 0.666 0.1764 0.91 0.593 1.4 0.116 0.21 0.58 0.2366 1.12 0.744 1.7 -0.0703 0.219 0.749 0.1257 0.932 0.606 1.43 PRS_PLINK_0.001 FALSE 1009 Injury, NOS Both 1499 17938 18 injuries & poisonings gray50 17938, 1499 4485, 352 4484, 393 4484, 379 4485, 375 0.0148 0.0241 0.539 0.2688 1.01 0.968 1.06 0.109 0.0762 0.152 0.8175 1.12 0.961 1.3 0.0765 0.0769 0.32 0.495 1.08 0.928 1.25 0.0634 0.077 0.41 0.3867 1.07 0.916 1.24 PRS_PLINK_0.001 FALSE 1010 Other tests Both 1107 12581 18 injuries & poisonings gray50 12581, 1107 3145, 259 3145, 287 3145, 274 3145, 287 0.00731 0.0311 0.814 0.08939 1.01 0.948 1.07 0.103 0.0891 0.249 0.6045 1.11 0.931 1.32 0.0512 0.0901 0.57 0.2445 1.05 0.882 1.26 0.0978 0.0892 0.273 0.564 1.1 0.926 1.31 PRS_PLINK_0.001 FALSE 1011 Complications of surgical and medical procedures Both 1599 19039 18 injuries & poisonings gray50 19039, 1599 4760, 371 4760, 390 4759, 399 4760, 439 0.00483 0.0238 0.839 0.07622 1 0.959 1.05 0.0486 0.0753 0.519 0.285 1.05 0.906 1.22 0.0694 0.0749 0.354 0.4511 1.07 0.926 1.24 0.165 0.0734 0.0247 1.608 1.18 1.02 1.36 PRS_PLINK_0.001 FALSE 1012 Late effect Both 12 212 18 injuries & poisonings gray50 212, 12 53, 2 53, 3 53, 4 53, 3 0.258 0.9 0.775 0.1108 1.29 0.222 7.55 0.499 0.814 0.54 0.2675 1.65 0.334 8.12 0.616 0.757 0.416 0.3808 1.85 0.42 8.17 0.369 0.804 0.646 0.1897 1.45 0.299 6.99 PRS_PLINK_0.001 TRUE 1013 Asphyxia and hypoxemia Both 53 661 18 injuries & poisonings gray50 661, 53 166, 17 165, 13 165, 13 165, 10 -0.579 0.481 0.228 0.6413 0.561 0.219 1.44 -0.243 0.367 0.507 0.295 0.784 0.382 1.61 -0.237 0.369 0.52 0.2837 0.789 0.383 1.63 -0.578 0.401 0.15 0.8247 0.561 0.256 1.23 PRS_PLINK_0.001 FALSE 1014 Effects of heat, cold and air pressure Both 12 157 18 injuries & poisonings gray50 157, 12 40, 4 39, 3 39, 3 39, 2 -0.46 0.965 0.634 0.198 0.632 0.0953 4.18 0.00623 0.743 0.993 0.002915 1.01 0.234 4.32 -0.0331 0.747 0.965 0.01564 0.967 0.224 4.18 -0.417 0.749 0.578 0.2383 0.659 0.152 2.86 PRS_PLINK_0.001 TRUE 1015 Effects of other external causes Both 672 9058 18 injuries & poisonings gray50 9058, 672 2265, 165 2264, 155 2264, 178 2265, 174 0.0092 0.0427 0.83 0.08113 1.01 0.928 1.1 -0.0616 0.115 0.593 0.2271 0.94 0.75 1.18 0.0735 0.112 0.511 0.2919 1.08 0.865 1.34 0.0549 0.112 0.625 0.2044 1.06 0.848 1.32 PRS_PLINK_0.001 FALSE 1019 Other ill-defined and unknown causes of morbidity and mortality Both 2787 34616 18 injuries & poisonings gray50 34616, 2787 8653, 681 8654, 731 8654, 678 8654, 697 -0.038 0.0263 0.148 0.8297 0.963 0.914 1.01 0.0703 0.0553 0.204 0.6907 1.07 0.963 1.2 -0.00545 0.0563 0.923 0.03489 0.995 0.891 1.11 0.0232 0.0559 0.678 0.1689 1.02 0.917 1.14 PRS_PLINK_0.001 FALSE