phewas_code phewas_string sex MatchedCases MatchedControls groupnum group color N N_Q1 N_Q2 N_Q3 N_Q4 PRS_BETA PRS_SEBETA PRS_P PRS_LOG10P PRS_OR PRS_CI1 PRS_CI2 Q1Q2_BETA Q1Q2_SEBETA Q1Q2_P Q1Q2_LOG10P Q1Q2_OR Q1Q2_CI1 Q1Q2_CI2 Q1Q3_BETA Q1Q3_SEBETA Q1Q3_P Q1Q3_LOG10P Q1Q3_OR Q1Q3_CI1 Q1Q3_CI2 Q1Q4_BETA Q1Q4_SEBETA Q1Q4_P Q1Q4_LOG10P Q1Q4_OR Q1Q4_CI1 Q1Q4_CI2 predictor exclude 008 Intestinal infection Both 7 45 1 infectious diseases blue 45, 7 11, 0 11, 2 11, 3 11, 2 0.022 0.487 0.964 0.016 1.02 0.406 3.28 2.11 2.41 0.382 0.418 8.24 0.114 90500 1.01 1.18 0.391 0.408 2.76 0.367 3940 1.21 1.8 0.5 0.301 3.36 0.0133 37600 PRS_PLINK_1e.06 TRUE 008.5 Bacterial enteritis Both 2 16 1 infectious diseases blue 16, 2 3, 0 4, 0 4, 1 4, 1 0.684 1.25 0.584 0.233 1.98 0.163 240 -0.0721 73.1 0.999 0 0.93 0.277 1.54 0.297 1210 1 0 1.35 0.375 57.8 PRS_PLINK_1e.06 TRUE 008.52 Intestinal infection due to C. difficile Both 1 11 1 infectious diseases blue 11, 1 3, 0 3, 0 2, 1 3, 0 0.844 2.86 0.768 0.115 2.32 0.0114 166 -0.353 2580 1 0 0.703 0.000252 1620 PRS_PLINK_1e.06 TRUE 008.6 Viral Enteritis Both 1 13 1 infectious diseases blue 13, 1 4, 0 3, 1 3, 0 3, 0 -0.332 1.9 0.861 0.065 0.717 0.0139 40.6 -0.0279 639 1 0 0.973 0.269 3.26 PRS_PLINK_1e.06 TRUE 010 Tuberculosis Both 2 3 1 infectious diseases blue 3, 2 1, 2 1, 0 1, 0 1, 2 -0.0814 1170 1 0 0.922 0.283 2.29 1.71e-05 2930 1 0 1 0.421 1.55 -1.25e-06 6010 1 0 1 0.328 3.59 PRS_PLINK_1e.06 TRUE 031 Diseases due to other mycobacteria Both 1 2 1 infectious diseases blue 2, 1 1, 0 1, 1 1, 0 1, 1 -0.0172 545 1 0 0.983 0.714 1.15 -0.0322 280 1 0 0.968 0.771 1.14 PRS_PLINK_1e.06 TRUE 038 Septicemia Both 1 34 1 infectious diseases blue 34, 1 8, 0 8, 0 8, 0 9, 1 0.338 0.576 0.557 0.254 1.4 0.451 7.85 0.351 1.4 0.802 0.096 1.42 0.0838 59.7 PRS_PLINK_1e.06 TRUE 038.1 Gram negative septicemia Both 1 9 1 infectious diseases blue 9, 1 3, 0 2, 0 2, 0 2, 1 -0.254 3.45 0.941 0.026 0.776 0.0044 252 0.253 1560 1 0 1.29 0.565 4.94 PRS_PLINK_1e.06 TRUE 038.2 Gram positive septicemia Both 0 3 1 infectious diseases blue 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 038.3 Bacteremia Both 0 18 1 infectious diseases blue 18, 0 5 4 4 5 PRS_PLINK_1e.06 TRUE 041 Bacterial infection NOS Both 4 52 1 infectious diseases blue 52, 4 12, 0 13, 0 13, 3 13, 1 0.483 0.52 0.353 0.453 1.62 0.598 23.7 0.336 1.24 0.786 0.104 1.4 0.00037 42.2 0.562 1.29 0.662 0.179 1.75 0.0582 98.9 PRS_PLINK_1e.06 TRUE 041.1 Staphylococcus infections Both 2 26 1 infectious diseases blue 26, 2 7, 0 6, 0 6, 2 7, 0 -0.132 0.68 0.846 0.073 0.876 0.123 9.5 0.801 1.71 0.64 0.194 2.23 0.114 570 PRS_PLINK_1e.06 TRUE 041.11 Methicillin sensitive Staphylococcus aureus Both 2 16 1 infectious diseases blue 16, 2 4, 0 4, 0 4, 1 4, 1 -0.0876 0.988 0.929 0.032 0.916 0.0926 21.8 0.0261 153 1 0 1.03 0.0448 156000 4.56 13800 1 0 95.7 138 1630 PRS_PLINK_1e.06 TRUE 041.12 Methicillin resistant Staphylococcus aureus Both 2 14 1 infectious diseases blue 14, 2 4, 0 3, 1 3, 1 4, 0 -0.0457 0.894 0.959 0.018 0.955 0.145 8.1 -0.101 2360 1 0 0.904 0.198 5.07 1 5210000 1 0 2.72 1.17 5.63 PRS_PLINK_1e.06 TRUE 041.2 Streptococcus infection Both 2 17 1 infectious diseases blue 17, 2 5, 0 4, 0 4, 0 4, 2 0.232 0.761 0.76 0.119 1.26 0.31 88.9 0.02 2.17 0.993 0.003 1.02 0.0268 36.8 PRS_PLINK_1e.06 TRUE 041.21 Rheumatic fever / chorea Both 0 1 1 infectious diseases blue 1, 0 PRS_PLINK_1e.06 TRUE 041.4 E. coli Both 2 12 1 infectious diseases blue 12, 2 3, 0 3, 0 3, 0 3, 2 1.76 2.91 0.545 0.263 5.81 0.0806 888000 2.87 116 0.98 0.009 17.7 22.8 593 PRS_PLINK_1e.06 TRUE 041.8 H. pylori Both 0 2 1 infectious diseases blue 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 041.9 Infection with drug-resistant microorganisms Both 0 5 1 infectious diseases blue 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 053 Herpes zoster Both 3 22 1 infectious diseases blue 22, 3 5, 1 5, 0 5, 1 6, 1 -0.385 0.797 0.629 0.201 0.68 0.0123 3.11 -0.0281 514 1 0 0.972 0.449 1.27 -0.537 5.12 0.916 0.038 0.584 8.17e-05 944 -0.577 1.84 0.754 0.123 0.562 0.00576 8.44 PRS_PLINK_1e.06 TRUE 053.1 Herpes zoster with nervous system complications Both 1 3 1 infectious diseases blue 3, 1 1, 0 1, 0 1, 1 1, 0 -0.0208 3790 1 0 0.979 0.452 2.06 0.00757 50.1 1 0 1.01 0.894 1.18 PRS_PLINK_1e.06 TRUE 054 Herpes simplex Both 3 22 1 infectious diseases blue 22, 3 5, 0 5, 1 5, 0 6, 2 -0.347 0.802 0.665 0.177 0.707 0.0975 9.2 -0.386 2.75 0.888 0.052 0.679 0.00493 29.5 -0.613 4.2 0.884 0.054 0.542 7.72e-05 1200 PRS_PLINK_1e.06 TRUE 070 Viral hepatitis Both 1 8 1 infectious diseases blue 8, 1 2, 0 2, 0 2, 0 2, 1 -0.0413 144 1 0 0.96 0.817 1.05 7.22 29200 1 0 1370 1.05e-09 1e+16 PRS_PLINK_1e.06 TRUE 070.2 Viral hepatitis B Both 1 1 1 infectious diseases blue 1, 1 -0.0134 70.6 1 0 0.987 0.97 1.03 PRS_PLINK_1e.06 TRUE 070.3 Viral hepatitis C Both 0 7 1 infectious diseases blue 7, 0 2 2 1 2 PRS_PLINK_1e.06 TRUE 070.4 Chronic hepatitis Both 0 1 1 infectious diseases blue 1, 0 PRS_PLINK_1e.06 TRUE 070.9 Hepatitis NOS Both 3 9 1 infectious diseases blue 9, 3 3, 2 2, 0 2, 0 2, 1 0.0941 3.02 0.975 0.011 1.1 0.979 1.18 -9.18 22000 1 0 0.000103 1.73e-22 1.51e+11 30.5 26400000 1 0 1.8e+13 1.54e-59 5.62e+88 0.804 54.1 0.988 0.005 2.23 0.0815 184 PRS_PLINK_1e.06 TRUE 071 Human immunodeficiency virus [HIV] disease Both 0 2 1 infectious diseases blue 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 071.1 HIV infection, symptomatic Both 0 2 1 infectious diseases blue 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 078 Viral warts & HPV Both 10 34 1 infectious diseases blue 34, 10 8, 2 8, 3 8, 2 9, 3 -0.149 0.459 0.746 0.128 0.862 0.341 2.3 -0.153 1.93 0.937 0.028 0.858 0.000549 70.2 0.87 1.51 0.563 0.249 2.39 0.185 106 -1.7 1.8 0.345 0.463 0.182 0.00181 3.81 PRS_PLINK_1e.06 TRUE 079 Viral infection Both 13 38 1 infectious diseases blue 38, 13 9, 6 9, 1 9, 3 10, 3 -0.273 0.349 0.433 0.364 0.761 0.394 1.42 -0.831 1.41 0.557 0.254 0.436 0.00812 5.4 -0.923 1.11 0.407 0.39 0.397 0.0351 2.57 -1.61 1.09 0.14 0.854 0.199 0.0189 1.2 PRS_PLINK_1e.06 TRUE 079.1 Varicella infection Both 8 32 1 infectious diseases blue 32, 8 7, 4 8, 0 8, 0 8, 4 -0.285 0.564 0.614 0.212 0.752 0.256 2.51 -1.52 1.99 0.445 0.352 0.219 0.000508 6.05 -1.2 1.56 0.441 0.355 0.3 0.00419 8.73 -1.15 1.42 0.419 0.378 0.318 0.0121 5.25 PRS_PLINK_1e.06 TRUE 079.2 Infectious mononucleosis Both 0 4 1 infectious diseases blue 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 079.9 Viremia, NOS Both 2 12 1 infectious diseases blue 12, 2 3, 0 3, 2 3, 0 3, 0 -0.156 0.783 0.842 0.074 0.856 0.125 5.76 -0.549 2580 1 0 0.577 0.00595 0.0155 PRS_PLINK_1e.06 TRUE 080 Postoperative infection Both 0 29 1 infectious diseases blue 29, 0 7 7 7 7 PRS_PLINK_1e.06 TRUE 081 Infection/inflammation of internal prosthetic device; implant; and graft Both 3 15 1 infectious diseases blue 15, 3 3, 0 4, 0 3, 1 4, 2 0.532 1.31 0.685 0.165 1.7 0.224 14300 -0.287 496000 1 0 0.751 0.00175 11.4 -1.09e-12 5.24 1 0 1 0.132 6.43 PRS_PLINK_1e.06 TRUE 090 Sexually transmitted infections (not HIV or hepatitis) Both 2 19 1 infectious diseases blue 19, 2 4, 1 5, 0 4, 0 5, 1 0.0451 0.591 0.939 0.027 1.05 0.312 8.85 -1.02 374 0.998 0.001 0.36 1.14e-05 10500000 -0.0487 165 1 0 0.952 0.0767 30.7 -0.923 3.06 0.763 0.118 0.397 0.00402 36.8 PRS_PLINK_1e.06 TRUE 110 Dermatophytosis / Dermatomycosis Both 13 33 1 infectious diseases blue 33, 13 9, 3 8, 3 8, 3 8, 3 0.1 0.395 0.799 0.097 1.11 0.53 2.39 -0.537 1.5 0.719 0.143 0.584 0.0157 62.9 -1.24 1.47 0.398 0.4 0.29 0.000559 2.98 1.32 1.51 0.382 0.418 3.76 0.197 344 PRS_PLINK_1e.06 TRUE 110.1 Dermatophytosis Both 13 31 1 infectious diseases blue 31, 13 8, 4 8, 2 7, 3 8, 3 0.0821 0.41 0.841 0.075 1.09 0.5 2.45 -0.977 1.39 0.484 0.315 0.377 0.000893 9.88 -1.14 1.4 0.415 0.382 0.32 0.000124 2.86 -1.15 1.66 0.488 0.312 0.315 0.254 5.69 PRS_PLINK_1e.06 TRUE 110.11 Dermatophytosis of nail Both 9 18 1 infectious diseases blue 18, 9 5, 3 4, 1 4, 2 5, 2 -0.117 0.622 0.851 0.07 0.89 0.237 3.76 0.161 1200 1 0 1.17 0.67 1.47 0.0423 544 1 0 1.04 0.541 1.8 -0.0519 1.45 0.971 0.013 0.949 0.272 4.42 PRS_PLINK_1e.06 TRUE 110.12 Althete's foot Both 4 15 1 infectious diseases blue 15, 4 4, 0 4, 1 3, 3 4, 0 -0.949 1.15 0.411 0.386 0.387 0.0253 2.42 -0.0345 7900000 1 0 0.966 0.27 5.07 4.89 37.8 0.897 0.047 133 106 169 PRS_PLINK_1e.06 TRUE 110.13 Dermatophytosis of the body Both 2 16 1 infectious diseases blue 16, 2 4, 0 4, 0 4, 1 4, 1 0.193 0.722 0.789 0.103 1.21 0.314 33.8 -0.0927 9.58 0.992 0.003 0.911 0.2 1.76 1.99 11200000 1 0 7.33 0.0227 7020 PRS_PLINK_1e.06 TRUE 110.2 Dermatomycoses Both 2 7 1 infectious diseases blue 7, 2 2, 0 2, 1 1, 0 2, 1 -0.464 9.28 0.96 0.018 0.629 0.108 3.65 -0.177 5660 1 0 0.838 0.0277 52.2 -0.00798 34.2 1 0 0.992 0.936 1.03 PRS_PLINK_1e.06 TRUE 112 Candidiasis Both 7 35 1 infectious diseases blue 35, 7 9, 2 9, 0 8, 2 9, 3 -0.535 0.721 0.458 0.339 0.585 0.0376 2.85 -1.45 1.82 0.424 0.372 0.234 1.05e-05 6.42 -1.75 1.71 0.306 0.515 0.173 0.00575 3.29 0.896 1.66 0.59 0.229 2.45 0.0636 3480 PRS_PLINK_1e.06 TRUE 112.3 Candidiasis of skin and nails Both 0 4 1 infectious diseases blue 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 117 Mycoses Both 2 4 1 infectious diseases blue 4, 2 1, 0 1, 1 1, 1 1, 0 0.00651 83.2 1 0 1.01 0.945 1.07 -0.00466 97.1 1 0 0.995 0.785 1.06 -0.00269 85 1 0 0.997 0.939 1.06 PRS_PLINK_1e.06 TRUE 117.4 Aspergillosis Both 2 1 1 infectious diseases blue 1, 2 -0.0219 1130 1 0 0.978 0.953 1.03 PRS_PLINK_1e.06 TRUE 130 Spirochetal infection Both 1 3 1 infectious diseases blue 3, 1 1, 1 1, 0 1, 0 1, 1 -0.00508 371 1 0 0.995 0.0601 1.1 13.7 33600 1 0 932000 2.8e-10 2.49e+18 3.31 103000 1 0 27.5 1.29e-14 2.22e+18 PRS_PLINK_1e.06 TRUE 130.1 Lyme disease Both 0 2 1 infectious diseases blue 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 131 Protozoan infection Both 0 2 1 infectious diseases blue 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 134 Helminthiases Both 1 1 1 infectious diseases blue 1, 1 0.0461 115 1 0 1.05 0.8 1.26 PRS_PLINK_1e.06 TRUE 134.1 Intestinal helminthiases Both 1 0 1 infectious diseases blue 0, 1 PRS_PLINK_1e.06 TRUE 136 Other infectious and parasitic diseases Both 6 41 1 infectious diseases blue 41, 6 10, 0 10, 4 10, 2 10, 0 -0.124 0.473 0.793 0.101 0.884 0.327 2.56 0.876 1.38 0.524 0.281 2.4 0.0976 67.5 0.679 1.65 0.68 0.168 1.97 0.00119 5100 PRS_PLINK_1e.06 TRUE 145 Cancer of mouth Both 1 10 2 neoplasms darkcyan 10, 1 2, 0 2, 0 2, 0 3, 1 0.0489 1.01 0.961 0.017 1.05 0.0825 6.06 0.049 906000 1 0 1.05 0.906 1.24 PRS_PLINK_1e.06 TRUE 145.1 Cancer of lip Both 0 1 2 neoplasms darkcyan 1, 0 PRS_PLINK_1e.06 TRUE 145.2 Cancer of tongue Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 145.3 Cancer of major salivary glands Both 1 2 2 neoplasms darkcyan 2, 1 1, 1 1, 0 1, 1 1, 0 45.3 7010000 1 0 4.77e+19 3.11e-37 1.89e+80 22.9 58500 1 0 8.99e+09 8.69e-16 6.14e+31 PRS_PLINK_1e.06 TRUE 145.4 Cancer of the gums Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 149 Cancer of larynx, pharynx, nasal cavities Both 1 10 2 neoplasms darkcyan 10, 1 2, 0 2, 0 2, 0 3, 1 0.012 1.1 0.991 0.004 1.01 0.119 11.4 0.116 1190 1 0 1.12 0.487 2.94 PRS_PLINK_1e.06 TRUE 149.1 Cancer of oropharynx Both 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 149.2 Cancer of nasopharynx Both 0 1 2 neoplasms darkcyan 1, 0 PRS_PLINK_1e.06 TRUE 149.4 Cancer of larynx Both 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 149.5 Hx of malignant neoplasm of oral cavity and pharynx Both 1 3 2 neoplasms darkcyan 3, 1 1, 0 1, 0 1, 1 1, 0 0.0551 1680 1 0 1.06 0.797 1.88 -0.00764 41 1 0 0.992 0.928 1.07 PRS_PLINK_1e.06 TRUE 149.9 Cancer of of nasal cavities Both 0 1 2 neoplasms darkcyan 1, 0 PRS_PLINK_1e.06 TRUE 150 Cancer of esophagus Both 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 151 Cancer of stomach Both 1 1 2 neoplasms darkcyan 1, 1 -0.000218 12.1 1 0 1 0.994 1.01 PRS_PLINK_1e.06 TRUE 153 Colorectal cancer Both 0 9 2 neoplasms darkcyan 9, 0 3 2 2 2 PRS_PLINK_1e.06 TRUE 153.2 Colon cancer Both 0 6 2 neoplasms darkcyan 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 153.3 Malignant neoplasm of rectum, rectosigmoid junction, and anus Both 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 155 Cancer of liver and intrahepatic bile duct Both 0 4 2 neoplasms darkcyan 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 155.1 Malignant neoplasm of liver, primary Both 0 4 2 neoplasms darkcyan 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 157 Pancreatic cancer Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 158 Neoplasm of unspecified nature of digestive system Both 2 10 2 neoplasms darkcyan 10, 2 3, 0 2, 1 2, 0 3, 1 -3.02 5.43 0.578 0.238 0.0487 0.04 0.0597 0.00531 1040 1 0 1.01 0.813 1.28 -0.443 507 0.999 0 0.642 0.174 1.65 PRS_PLINK_1e.06 TRUE 159 Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum Both 1 9 2 neoplasms darkcyan 9, 1 3, 0 2, 0 2, 0 2, 1 3.03 7.32 0.679 0.168 20.8 0.00126 25.4 -0.0216 41.6 1 0 0.979 0.925 1.16 PRS_PLINK_1e.06 TRUE 159.2 Malignant neoplasm of small intestine, including duodenum Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 159.3 Malignant neoplasm of gallbladder and extrahepatic bile ducts Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 159.4 Malignant neoplasm of retroperitoneum and peritoneum Both 0 1 2 neoplasms darkcyan 1, 0 PRS_PLINK_1e.06 TRUE 165 Cancer within the respiratory system Both 0 12 2 neoplasms darkcyan 12, 0 3 3 3 3 PRS_PLINK_1e.06 TRUE 165.1 Cancer of bronchus; lung Both 0 10 2 neoplasms darkcyan 10, 0 3 2 2 3 PRS_PLINK_1e.06 TRUE 170 Cancer of bone and connective tissue Both 0 15 2 neoplasms darkcyan 15, 0 3 4 3 4 PRS_PLINK_1e.06 TRUE 170.1 Bone cancer Both 0 12 2 neoplasms darkcyan 12, 0 2 3 3 3 PRS_PLINK_1e.06 TRUE 170.2 Cancer of connective tissue Both 0 5 2 neoplasms darkcyan 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 172 Skin cancer Both 5 43 2 neoplasms darkcyan 43, 5 10, 1 11, 0 10, 3 11, 1 0.184 0.508 0.718 0.144 1.2 0.438 4.78 -0.757 1.98 0.702 0.153 0.469 0.000482 42.9 3.72 2.77 0.179 0.747 41.1 0.418 45900000 0.842 1.56 0.59 0.229 2.32 0.111 1e+05 PRS_PLINK_1e.06 TRUE 172.1 Melanomas of skin, dx or hx Both 4 33 2 neoplasms darkcyan 33, 4 9, 0 8, 0 8, 3 8, 1 0.449 0.612 0.463 0.335 1.57 0.466 10.8 1.89 1.76 0.283 0.549 6.61 0.282 51400000 0.661 1.58 0.675 0.171 1.94 0.0762 87.1 PRS_PLINK_1e.06 TRUE 172.11 Melanomas of skin Both 1 19 2 neoplasms darkcyan 19, 1 5, 0 5, 0 4, 0 5, 1 0.134 0.808 0.868 0.062 1.14 0.0907 14.5 -0.372 3.4 0.913 0.04 0.689 0.00225 93.7 PRS_PLINK_1e.06 TRUE 172.2 Other non-epithelial cancer of skin Both 4 37 2 neoplasms darkcyan 37, 4 9, 1 9, 0 9, 3 9, 0 0.107 0.511 0.833 0.079 1.11 0.419 4.11 -0.394 2.35 0.867 0.062 0.675 0.000269 294 1.31 1.49 0.38 0.42 3.71 0.324 151 0.106 1.73 0.951 0.022 1.11 0.00145 3860 PRS_PLINK_1e.06 TRUE 172.21 Basal cell carcinoma Both 4 22 2 neoplasms darkcyan 22, 4 6, 1 5, 0 5, 3 6, 0 0.0953 0.681 0.889 0.051 1.1 0.332 5.72 0.665 3 0.825 0.084 1.94 0.0153 201 4.42 3.2 0.167 0.778 83 0.754 2250000 1.01 3.76 0.788 0.104 2.75 0.00298 8280 PRS_PLINK_1e.06 TRUE 172.22 Squamous cell carcinoma Both 0 12 2 neoplasms darkcyan 12, 0 3 3 3 3 PRS_PLINK_1e.06 TRUE 172.3 Carcinoma in situ of skin Both 0 11 2 neoplasms darkcyan 11, 0 3 3 2 3 PRS_PLINK_1e.06 TRUE 173 Neoplasm of uncertain behavior of skin Both 1 26 2 neoplasms darkcyan 26, 1 6, 1 6, 0 6, 0 7, 0 -0.46 0.72 0.523 0.282 0.631 0.124 6.59 0.15 2.32 0.949 0.023 1.16 0.0137 110 -0.469 2.35 0.841 0.075 0.625 0.019 48.6 -0.583 2.25 0.795 0.1 0.558 0.00135 99.1 PRS_PLINK_1e.06 TRUE 174 Breast cancer Both 3 18 2 neoplasms darkcyan 18, 3 4, 2 4, 1 4, 0 5, 0 -0.159 0.716 0.824 0.084 0.853 0.19 5.7 2.75 4.72 0.56 0.252 15.7 0.00995 2660000 -0.58 8.02 0.942 0.026 0.56 0.372 0.865 1.22 2.99 0.685 0.165 3.37 0.0365 45700 PRS_PLINK_1e.06 TRUE 174.1 Breast cancer [female] Female 3 19 2 neoplasms darkcyan 19, 3 4, 3 5, 0 4, 0 5, 0 -0.154 0.712 0.829 0.081 0.858 0.218 5.63 1.19 3.66 0.746 0.127 3.28 0.0207 208000 -1.46 6.12 0.811 0.091 0.232 0.163 1.96 1.68 3.08 0.585 0.233 5.39 0.0586 6.51 PRS_PLINK_1e.06 TRUE 174.11 Malignant neoplasm of female breast Female 3 18 2 neoplasms darkcyan 18, 3 4, 2 4, 1 4, 0 5, 0 -0.159 0.716 0.824 0.084 0.853 0.19 5.7 2.75 4.72 0.56 0.252 15.7 0.00995 2660000 -0.58 8.02 0.942 0.026 0.56 0.372 0.865 1.22 2.99 0.685 0.165 3.37 0.0365 45700 PRS_PLINK_1e.06 TRUE 174.3 Neoplasm of uncertain behavior of breast Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 175 Acquired absence of breast Female 1 5 2 neoplasms darkcyan 5, 1 2, 1 1, 0 1, 0 1, 0 0.0271 177 1 0 1.03 0.697 0.783 0.342 4130 1 0 1.41 0.74 5.38 0.168 2180 1 0 1.18 0.727 3.15 -0.192 3140 1 0 0.825 0.0294 2.29 PRS_PLINK_1e.06 TRUE 180 Cervical cancer and dysplasia Female 2 11 2 neoplasms darkcyan 11, 2 2, 1 3, 0 2, 1 3, 0 0.127 1.16 0.913 0.04 1.14 0.00164 39.3 0.018 2120 1 0 1.02 0.387 1.97 0.116 2290 1 0 1.12 0.516 1.19 -0.225 559 1 0 0.798 0.139 3.36 PRS_PLINK_1e.06 TRUE 180.1 Cervical cancer Female 1 4 2 neoplasms darkcyan 4, 1 1, 1 1, 0 1, 0 1, 1 0.115 2260 1 0 1.12 0.766 1.32 PRS_PLINK_1e.06 TRUE 180.3 Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia] Female 1 11 2 neoplasms darkcyan 11, 1 2, 0 3, 0 2, 1 3, 0 0.409 1.44 0.776 0.11 1.51 0.0571 345 0.15 1850 1 0 1.16 0.666 1.25 PRS_PLINK_1e.06 TRUE 182 Malignant neoplasm of uterus Female 0 5 2 neoplasms darkcyan 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 184 Cancer of other female genital organs Female 0 6 2 neoplasms darkcyan 6, 0 1 1 1 2 PRS_PLINK_1e.06 TRUE 184.1 Malignant neoplasm of ovary and other uterine adnexa Female 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 184.11 Malignant neoplasm of ovary Female 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 184.2 Cancer of other female genital organs (excluding uterus and ovary) Female 0 5 2 neoplasms darkcyan 5, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 185 Cancer of prostate Male 0 9 2 neoplasms darkcyan 9, 0 3 2 2 2 PRS_PLINK_1e.06 TRUE 187 Cancer of other male genital organs Male 1 2 2 neoplasms darkcyan 2, 1 1, 0 1, 1 1, 0 1, 1 0.0401 2790 1 0 1.04 0.861 1.65 -15.8 422000 1 0 1.43e-07 4.1e-24 3.92e+14 PRS_PLINK_1e.06 TRUE 187.2 Malignant neoplasm of testis Male 1 3 2 neoplasms darkcyan 3, 1 1, 0 1, 0 1, 1 1, 0 0.0211 329 1 0 1.02 0.863 1.25 -15.8 422000 1 0 1.43e-07 4.1e-24 3.92e+14 PRS_PLINK_1e.06 TRUE 187.8 Neoplasm of uncertain behavior of male genital organs Male 0 1 2 neoplasms darkcyan 1, 0 PRS_PLINK_1e.06 TRUE 189 Cancer of urinary organs (incl. kidney and bladder) Both 0 19 2 neoplasms darkcyan 19, 0 5 5 4 5 PRS_PLINK_1e.06 TRUE 189.1 Cancer of kidney and renal pelvis Both 0 10 2 neoplasms darkcyan 10, 0 3 2 2 3 PRS_PLINK_1e.06 TRUE 189.11 Malignant neoplasm of kidney, except pelvis Both 0 9 2 neoplasms darkcyan 9, 0 3 2 2 2 PRS_PLINK_1e.06 TRUE 189.12 Malignant neoplasm of renal pelvis Both 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 189.2 Cancer of bladder Both 0 10 2 neoplasms darkcyan 10, 0 3 2 2 3 PRS_PLINK_1e.06 TRUE 189.21 Malignant neoplasm of bladder Both 0 8 2 neoplasms darkcyan 8, 0 2 2 2 2 PRS_PLINK_1e.06 TRUE 189.4 Malignant neoplasm of other urinary organs Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 190 Cancer of eye Both 0 1 2 neoplasms darkcyan 1, 0 PRS_PLINK_1e.06 TRUE 191 Manlignant and unknown neoplasms of brain and nervous system Both 0 10 2 neoplasms darkcyan 10, 0 3 2 2 3 PRS_PLINK_1e.06 TRUE 191.1 Cancer of brain and nervous system Both 0 7 2 neoplasms darkcyan 7, 0 2 2 1 2 PRS_PLINK_1e.06 TRUE 191.11 Cancer of brain Both 0 8 2 neoplasms darkcyan 8, 0 2 2 2 2 PRS_PLINK_1e.06 TRUE 193 Thyroid cancer Both 0 16 2 neoplasms darkcyan 16, 0 4 4 4 4 PRS_PLINK_1e.06 TRUE 194 Cancer of other endocrine glands Both 0 11 2 neoplasms darkcyan 11, 0 2 3 2 3 PRS_PLINK_1e.06 TRUE 195 Cancer, suspected or other Both 9 48 2 neoplasms darkcyan 48, 9 11, 2 12, 3 12, 2 12, 2 0.261 0.422 0.536 0.27 1.3 0.593 3.7 -0.241 1.44 0.867 0.062 0.785 0.0127 16.4 3.65 2.72 0.18 0.745 38.4 0.372 55.8 1.09 1.37 0.424 0.372 2.98 0.159 2570 PRS_PLINK_1e.06 TRUE 195.1 Malignant neoplasm, other Both 8 49 2 neoplasms darkcyan 49, 8 12, 2 12, 2 12, 2 12, 2 0.336 0.436 0.44 0.356 1.4 0.626 4.56 -0.0287 1.39 0.983 0.007 0.972 0.0434 20.9 3.19 2.49 0.2 0.699 24.4 0.284 36.1 1.14 1.36 0.404 0.393 3.11 0.211 185 PRS_PLINK_1e.06 TRUE 195.3 Malignant neoplasm of head, face, and neck Both 0 8 2 neoplasms darkcyan 8, 0 1 2 2 2 PRS_PLINK_1e.06 TRUE 196 Radiotherapy Both 0 14 2 neoplasms darkcyan 14, 0 3 3 3 4 PRS_PLINK_1e.06 TRUE 197 Chemotherapy Both 1 33 2 neoplasms darkcyan 33, 1 8, 0 8, 0 8, 0 8, 1 0.0773 0.517 0.881 0.055 1.08 0.333 27.2 0.486 1.47 0.74 0.131 1.63 0.0303 144 PRS_PLINK_1e.06 TRUE 198 Secondary malignant neoplasm Both 0 31 2 neoplasms darkcyan 31, 0 7 8 7 8 PRS_PLINK_1e.06 TRUE 198.1 Secondary malignancy of lymph nodes Both 0 25 2 neoplasms darkcyan 25, 0 6 6 6 6 PRS_PLINK_1e.06 TRUE 198.2 Secondary malignancy of respiratory organs Both 0 6 2 neoplasms darkcyan 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 198.3 Secondary malignant neoplasm of digestive systems Both 0 5 2 neoplasms darkcyan 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 198.4 Secondary malignant neoplasm of liver Both 0 6 2 neoplasms darkcyan 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 198.5 Secondary malignancy of brain/spine Both 0 7 2 neoplasms darkcyan 7, 0 2 2 1 2 PRS_PLINK_1e.06 TRUE 198.6 Secondary malignancy of bone Both 0 9 2 neoplasms darkcyan 9, 0 2 2 2 2 PRS_PLINK_1e.06 TRUE 199 Neoplasm of uncertain behavior Both 4 48 2 neoplasms darkcyan 48, 4 11, 1 12, 1 12, 1 12, 1 0.605 0.642 0.347 0.46 1.83 0.0632 11.1 -0.366 1.55 0.814 0.09 0.694 0.0413 99.1 0.465 1.48 0.753 0.123 1.59 0.0609 49 0.182 1.42 0.898 0.047 1.2 0.0159 123 PRS_PLINK_1e.06 TRUE 199.4 Neurofibromatosis Both 0 1 2 neoplasms darkcyan 1, 0 PRS_PLINK_1e.06 TRUE 200 Myeloproliferative disease Both 0 13 2 neoplasms darkcyan 13, 0 4 3 3 3 PRS_PLINK_1e.06 TRUE 200.1 Polycythemia vera Both 0 5 2 neoplasms darkcyan 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 201 Hodgkin's disease Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 202 Cancer of other lymphoid, histiocytic tissue Both 1 15 2 neoplasms darkcyan 15, 1 3, 0 4, 1 3, 0 4, 0 0.515 1.32 0.697 0.157 1.67 0.176 506 -0.000364 2160 1 0 1 0.453 2.26 PRS_PLINK_1e.06 TRUE 202.2 Non-Hodgkins lymphoma Both 1 14 2 neoplasms darkcyan 14, 1 3, 1 3, 0 3, 0 4, 0 0.0228 0.857 0.979 0.009 1.02 0.272 5.25 2.6 1310 0.998 0.001 13.4 3.46e-05 839000 -0.00599 10 1 0 0.994 0.916 1.08 -1.95 546 0.997 0.001 0.143 1.2e-05 1.4 PRS_PLINK_1e.06 TRUE 202.21 Nodular lymphoma Both 1 8 2 neoplasms darkcyan 8, 1 2, 0 2, 1 2, 0 2, 0 1.47 34.5 0.966 0.015 4.35 0.0172 1140 0.113 1920 1 0 1.12 0.684 1.12 PRS_PLINK_1e.06 TRUE 202.22 Reticulosarcoma Both 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 202.24 Large cell lymphoma Both 0 1 2 neoplasms darkcyan 1, 0 PRS_PLINK_1e.06 TRUE 204 Leukemia Both 1 10 2 neoplasms darkcyan 10, 1 3, 0 2, 0 2, 0 3, 1 -0.125 15.1 0.993 0.003 0.882 0.874 0.891 -0.0886 769 1 0 0.915 0.562 1.39 PRS_PLINK_1e.06 TRUE 204.1 Lymphoid leukemia Both 0 5 2 neoplasms darkcyan 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 204.11 Lymphoid leukemia, acute Both 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 204.12 Lymphoid leukemia, chronic Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 204.2 Myeloid leukemia Both 0 7 2 neoplasms darkcyan 7, 0 2 2 1 2 PRS_PLINK_1e.06 TRUE 204.21 Myeloid leukemia, acute Both 0 4 2 neoplasms darkcyan 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 204.4 Multiple myeloma Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 208 Benign neoplasm of colon Both 24 38 2 neoplasms darkcyan 38, 24 9, 3 9, 9 9, 6 10, 6 0.203 0.297 0.495 0.305 1.23 0.722 2.2 0.812 1.2 0.499 0.302 2.25 0.312 24.1 0.817 1.08 0.45 0.346 2.26 0.406 19.9 1.1 1.18 0.351 0.455 3.01 0.426 121 PRS_PLINK_1e.06 TRUE 209 Neuroendocrine tumors Both 1 3 2 neoplasms darkcyan 3, 1 1, 1 1, 0 1, 0 1, 1 0.161 5420 1 0 1.17 0.547 1.27 0.0117 182 1 0 1.01 0.927 1.12 0.00625 137 1 0 1.01 0.901 1.1 PRS_PLINK_1e.06 TRUE 210 Benign neoplasm of lip, oral cavity, and pharynx Both 2 17 2 neoplasms darkcyan 17, 2 5, 1 4, 0 4, 0 4, 1 0.129 0.746 0.862 0.064 1.14 0.206 45.7 0.215 168 0.999 0 1.24 7.37e-07 1800000 -0.187 37.4 0.996 0.002 0.83 0.00263 1.41 0.725 2.33 0.755 0.122 2.07 0.0629 75.4 PRS_PLINK_1e.06 TRUE 211 Benign neoplasm of other parts of digestive system Both 19 43 2 neoplasms darkcyan 43, 19 10, 0 11, 6 10, 4 11, 9 0.594 0.356 0.0956 1.019 1.81 0.964 3.88 1.95 2.34 0.404 0.394 7.05 0.05 18600000 1.49 1.44 0.303 0.519 4.42 0.399 159 2.3 1.27 0.0702 1.154 9.93 1.34 3640 PRS_PLINK_1e.06 TRUE 212 Benign neoplasm of respiratory and intrathoracic organs Both 4 14 2 neoplasms darkcyan 14, 4 4, 2 3, 0 3, 2 4, 0 -1.98 1.51 0.19 0.722 0.138 0.00437 1.84 -1.45 9.85 0.883 0.054 0.236 0.22 0.251 -4.08 5.37 0.447 0.35 0.0169 5.89e-16 17.6 2.35 5.11 0.646 0.19 10.5 0.012 57000 PRS_PLINK_1e.06 TRUE 213 Benign neoplasm of bone and articular cartilage Both 0 14 2 neoplasms darkcyan 14, 0 3 3 3 4 PRS_PLINK_1e.06 TRUE 214 Lipoma Both 3 12 2 neoplasms darkcyan 12, 3 3, 2 3, 0 3, 1 3, 0 -0.339 0.91 0.71 0.149 0.713 0.0157 3.07 -0.0299 411 1 0 0.971 0.242 1.61 0.059 641 1 0 1.06 0.659 1.32 0.149 9160000 1 0 1.16 0.0429 476 PRS_PLINK_1e.06 TRUE 214.1 Lipoma of skin and subcutaneous tissue Both 1 6 2 neoplasms darkcyan 6, 1 2, 0 1, 1 1, 0 2, 0 1.33e-05 1970 1 0 1 0.714 1.39 0.0687 71800 1 0 1.07 0.0135 3.84 PRS_PLINK_1e.06 TRUE 215 Other benign neoplasm of connective and other soft tissue Both 9 45 2 neoplasms darkcyan 45, 9 11, 2 11, 5 11, 1 11, 1 -0.458 0.519 0.378 0.423 0.633 0.193 1.81 1.26 1.42 0.374 0.427 3.52 0.271 355 -0.632 1.32 0.632 0.199 0.532 0.000835 5.21 -1.24 1.37 0.363 0.44 0.288 5.33e-06 5.79 PRS_PLINK_1e.06 TRUE 216 Benign neoplasm of skin Both 20 44 2 neoplasms darkcyan 44, 20 10, 4 11, 7 11, 3 11, 6 -0.0884 0.32 0.782 0.107 0.915 0.501 1.7 -0.283 1.16 0.807 0.093 0.753 0.09 6.47 -0.788 1.05 0.452 0.345 0.455 0.0488 2.73 0.0689 1.05 0.947 0.023 1.07 0.155 7.72 PRS_PLINK_1e.06 TRUE 216.1 Screening for malignant neoplasms of the skin Both 0 5 2 neoplasms darkcyan 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 217 Vascular hamartomas and non-neoplastic nevi Both 1 16 2 neoplasms darkcyan 16, 1 4, 0 4, 0 4, 1 4, 0 0.187 0.878 0.832 0.08 1.21 0.163 12.4 -0.525 725 0.999 0 0.592 0.253 0.758 PRS_PLINK_1e.06 TRUE 217.1 Nevus, non-neoplastic Both 1 15 2 neoplasms darkcyan 15, 1 4, 0 4, 0 3, 1 4, 0 0.101 0.955 0.916 0.038 1.11 0.0884 7.98 -0.0697 1150 1 0 0.933 0.525 1.27 PRS_PLINK_1e.06 TRUE 218 Benign neoplasm of uterus Female 10 18 2 neoplasms darkcyan 18, 10 4, 2 4, 3 4, 4 5, 1 -0.0167 0.525 0.975 0.011 0.983 0.395 2.54 0.294 1.67 0.861 0.065 1.34 0.0799 167 2.99 4.17 0.472 0.326 20 0.0413 264000 -1.18 3.93 0.763 0.117 0.306 8.75e-08 255 PRS_PLINK_1e.06 TRUE 218.1 Uterine leiomyoma Female 3 16 2 neoplasms darkcyan 16, 3 3, 1 4, 1 4, 1 4, 0 0.019 0.788 0.981 0.008 1.02 0.254 4.49 0.54 2.04 0.792 0.101 1.72 0.0816 36.4 -1.55 133 0.991 0.004 0.213 0.0117 0.0133 -0.445 47200000 1 0 0.641 0.0179 817 PRS_PLINK_1e.06 TRUE 218.2 Other benign neoplasm of uterus Female 10 17 2 neoplasms darkcyan 17, 10 4, 2 4, 3 4, 3 4, 2 -0.0293 0.531 0.956 0.02 0.971 0.385 2.51 0.294 1.67 0.861 0.065 1.34 0.0799 167 3.31 4.19 0.43 0.367 27.3 0.0522 229000 -2.24 4.31 0.604 0.219 0.107 7.35e-08 43.7 PRS_PLINK_1e.06 TRUE 220 Benign neoplasm of ovary Female 1 8 2 neoplasms darkcyan 8, 1 1, 0 2, 0 2, 1 2, 0 1.67 3.14 0.596 0.225 5.3 0.133 5.82 0.152 361 1 0 1.16 0.398 2.68 PRS_PLINK_1e.06 TRUE 221 Benign neoplasm of other female genital organs Female 5 13 2 neoplasms darkcyan 13, 5 3, 2 3, 1 3, 2 3, 0 0.047 0.96 0.961 0.017 1.05 0.0927 6.26 -0.0262 14.6 0.999 0.001 0.974 0.782 1.34 9.15 40.9 0.823 0.085 9420 4920 18900 0.0412 689 1 0 1.04 0.492 2.34 PRS_PLINK_1e.06 TRUE 222 Benign neoplasm of male genital organs Male 1 8 2 neoplasms darkcyan 8, 1 2, 0 2, 0 2, 1 2, 0 0.306 14.8 0.983 0.007 1.36 1.03 2.01 0.198 2380 1 0 1.22 0.384 4.88 PRS_PLINK_1e.06 TRUE 223 Benign neoplasm of kidney and other urinary organs Both 2 7 2 neoplasms darkcyan 7, 2 2, 1 2, 0 1, 0 2, 1 0.0458 13.4 0.997 0.001 1.05 0.753 0.823 0.0127 44.5 1 0 1.01 0.96 1.08 0.00841 43.5 1 0 1.01 0.925 1.2 0.432 1540 1 0 1.54 0.68 1.82 PRS_PLINK_1e.06 TRUE 224 Benign neoplasm of eye Both 2 8 2 neoplasms darkcyan 8, 2 2, 0 2, 0 2, 1 2, 1 -6.97 35400000 1 0 0.000937 5.06e-14 7.05 2.35 1260 0.999 0.001 10.5 9.7e-11 1.32e+13 -0.174 5940 1 0 0.841 0.163 1.84 PRS_PLINK_1e.06 TRUE 224.1 Benign neoplasm of eye, uveal Both 2 10 2 neoplasms darkcyan 10, 2 3, 0 2, 0 2, 1 3, 1 0.312 2.38 0.896 0.048 1.37 0.041 137 0.0216 471 1 0 1.02 0.76 1.74 0.0263 101 1 0 1.03 0.831 1.75 PRS_PLINK_1e.06 TRUE 225 Benign neoplasm of brain and other parts of nervous system Both 0 13 2 neoplasms darkcyan 13, 0 4 3 3 3 PRS_PLINK_1e.06 TRUE 225.1 Benign neoplasm of brain, cranial nerves, meninges Both 0 11 2 neoplasms darkcyan 11, 0 3 3 2 3 PRS_PLINK_1e.06 TRUE 225.2 Benign neoplasm of spinal cord, meninges Both 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 226 Benign neoplasm of thyroid glands Both 0 14 2 neoplasms darkcyan 14, 0 4 3 3 4 PRS_PLINK_1e.06 TRUE 227 Benign neoplasm of other endocrine glands and related structures Both 0 16 2 neoplasms darkcyan 16, 0 4 4 4 4 PRS_PLINK_1e.06 TRUE 227.1 Benign neoplasm of adrenal gland Both 0 5 2 neoplasms darkcyan 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 227.2 Benign neoplasm of parathyroid gland Both 0 7 2 neoplasms darkcyan 7, 0 2 2 1 2 PRS_PLINK_1e.06 TRUE 227.3 Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch) Both 0 4 2 neoplasms darkcyan 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 228 Hemangioma and lymphangioma, any site Both 1 28 2 neoplasms darkcyan 28, 1 7, 0 7, 0 7, 1 7, 0 0.284 0.694 0.683 0.166 1.33 0.151 14 0.6 2.12 0.777 0.11 1.82 0.0293 988 PRS_PLINK_1e.06 TRUE 228.1 Hemangioma of skin and subcutaneous tissue Both 1 16 2 neoplasms darkcyan 16, 1 4, 0 4, 0 4, 1 4, 0 0.204 0.707 0.773 0.112 1.23 0.314 15.3 -0.153 351 1 0 0.858 0.587 1.04 PRS_PLINK_1e.06 TRUE 229 Benign neoplasm of unspecified sites Both 4 45 2 neoplasms darkcyan 45, 4 11, 2 11, 1 11, 0 11, 1 -0.492 0.652 0.451 0.346 0.612 0.0903 8.34 0.549 1.44 0.703 0.153 1.73 0.00452 77.8 -0.97 1.54 0.529 0.276 0.379 0.017 4440 1.22 1.86 0.513 0.29 3.38 0.0531 794 PRS_PLINK_1e.06 TRUE 229.1 Benign neoplasm of lymph nodes Both 1 30 2 neoplasms darkcyan 30, 1 7, 1 7, 0 7, 0 8, 0 -0.11 0.587 0.852 0.07 0.896 0.049 4.9 -0.00176 2.3 0.999 0 0.998 0.0109 332 0.24 3.01 0.937 0.028 1.27 0.00894 62100 0.702 1.98 0.723 0.141 2.02 0.0522 11900 PRS_PLINK_1e.06 TRUE 240 Simple and unspecified goiter Both 2 15 3 endocrine/metabolic brown 15, 2 3, 2 4, 0 3, 0 4, 0 0.0495 1.25 0.968 0.014 1.05 0.00119 13.2 -1.03 5950000 1 0 0.358 0.0372 4.15 -0.0715 171 1 0 0.931 0.567 1.26 -0.326 1460 1 0 0.722 0.14 2.56 PRS_PLINK_1e.06 TRUE 241 Nontoxic nodular goiter Both 1 31 3 endocrine/metabolic brown 31, 1 7, 1 8, 0 7, 0 8, 0 -0.493 0.633 0.436 0.36 0.611 0.0445 2.23 -0.337 2.31 0.884 0.053 0.714 0.00117 341 -0.654 1.73 0.706 0.151 0.52 0.00781 61.9 -0.54 1.95 0.781 0.107 0.583 0.000896 524 PRS_PLINK_1e.06 TRUE 241.1 Nontoxic uninodular goiter Both 0 30 3 endocrine/metabolic brown 30, 0 7 7 7 8 PRS_PLINK_1e.06 TRUE 241.2 Nontoxic multinodular goiter Both 0 16 3 endocrine/metabolic brown 16, 0 4 4 4 4 PRS_PLINK_1e.06 TRUE 242 Thyrotoxicosis with or without goiter Both 2 20 3 endocrine/metabolic brown 20, 2 4, 0 5, 0 5, 2 5, 0 -0.206 0.729 0.778 0.109 0.814 0.215 7.39 -0.907 2.71 0.738 0.132 0.404 0.00426 92.3 PRS_PLINK_1e.06 TRUE 242.1 Graves' disease Both 1 9 3 endocrine/metabolic brown 9, 1 2, 0 2, 0 2, 1 2, 0 0.0143 130 1 0 1.01 0.952 1.09 0.0764 1520 1 0 1.08 0.659 1.1 PRS_PLINK_1e.06 TRUE 242.2 Toxic multinodular goiter Both 0 2 3 endocrine/metabolic brown 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 242.3 Exophthalmos Both 2 5 3 endocrine/metabolic brown 5, 2 2, 1 1, 1 1, 0 1, 0 -0.107 1760 1 0 0.898 0.858 1.33 0.604 15800 1 0 1.83 0.138 2.69 -0.6 35000 1 0 0.549 0.319 3.82 -0.292 11900 1 0 0.747 0.658 2.52 PRS_PLINK_1e.06 TRUE 242.31 Thyrotoxic exophthalmos Both 1 2 3 endocrine/metabolic brown 2, 1 1, 1 1, 0 1, 1 1, 0 -0.129 16400 1 0 0.879 0.0795 6.23 8.25 746000 1 0 3810 1.37e-10 4.19e+16 PRS_PLINK_1e.06 TRUE 244 Hypothyroidism Both 11 44 3 endocrine/metabolic brown 44, 11 10, 6 11, 2 11, 2 11, 1 -0.811 0.446 0.0687 1.163 0.444 0.158 0.99 0.337 1.32 0.798 0.098 1.4 0.0196 40.6 -1.04 1.18 0.377 0.424 0.353 0.009 2.62 -1.17 1.09 0.281 0.552 0.31 0.0357 1.96 PRS_PLINK_1e.06 TRUE 244.1 Secondary hypothyroidism Both 2 28 3 endocrine/metabolic brown 28, 2 7, 0 7, 0 7, 2 7, 0 -0.942 0.944 0.318 0.497 0.39 0.0143 4.57 0.0755 1.66 0.964 0.016 1.08 0.0146 25 PRS_PLINK_1e.06 TRUE 244.2 Acquired hypothyroidism Both 5 21 3 endocrine/metabolic brown 21, 5 6, 3 5, 0 5, 1 5, 1 -0.587 0.613 0.338 0.471 0.556 0.153 1.57 -0.0186 1.92 0.992 0.003 0.982 0.0192 8.28 -1.8 2.54 0.478 0.32 0.166 1.17e-05 7.22 -0.558 1.5 0.709 0.149 0.572 0.0466 5.41 PRS_PLINK_1e.06 TRUE 244.4 Hypothyroidism NOS Both 10 44 3 endocrine/metabolic brown 44, 10 10, 6 11, 1 11, 2 11, 1 -0.856 0.466 0.066 1.18 0.425 0.14 0.982 0.344 1.44 0.811 0.091 1.41 0.041 51.2 -1.04 1.18 0.377 0.424 0.353 0.009 2.62 -1.17 1.09 0.281 0.552 0.31 0.0357 1.96 PRS_PLINK_1e.06 TRUE 245 Thyroiditis Both 1 16 3 endocrine/metabolic brown 16, 1 4, 1 4, 0 4, 0 4, 0 -0.858 1.25 0.494 0.306 0.424 0.00659 3.41 6.13 819 0.994 0.003 462 130 773 -3.27 36.6 0.929 0.032 0.0378 3.56e-05 28.1 -5.69 10.5 0.589 0.23 0.00338 6.77e-07 0.00373 PRS_PLINK_1e.06 TRUE 245.2 Chronic thyroiditis Both 1 14 3 endocrine/metabolic brown 14, 1 4, 1 3, 0 3, 0 4, 0 -1.31 1.73 0.449 0.348 0.27 0.00195 3.4 0.661 13800000 1 0 1.94 0.00113 33300 -2.66 9400000 1 0 0.07 5.09e-05 50.6 -5.69 10.5 0.589 0.23 0.00338 6.77e-07 0.00373 PRS_PLINK_1e.06 TRUE 245.21 Chronic lymphocytic thyroiditis Both 1 13 3 endocrine/metabolic brown 13, 1 4, 1 3, 0 3, 0 3, 0 -1.28 1.71 0.454 0.343 0.279 0.00356 3.34 0.895 2330 1 0 2.45 0.0446 471 -2.33 3820000 1 0 0.0978 0.00124 6.32 -1.46 4480 1 0 0.232 1.74e-05 197 PRS_PLINK_1e.06 TRUE 246 Other disorders of thyroid Both 8 40 3 endocrine/metabolic brown 40, 8 9, 4 10, 2 10, 1 10, 1 -0.642 0.481 0.182 0.739 0.526 0.161 1.3 0.0373 1.37 0.978 0.01 1.04 0.007 48.5 -0.44 1.26 0.728 0.138 0.644 0.00444 7.98 -0.642 1.32 0.627 0.203 0.526 0.0283 4.94 PRS_PLINK_1e.06 TRUE 246.2 Thyroid cyst Both 0 2 3 endocrine/metabolic brown 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 246.7 Abnormal results of function study of thyroid Both 1 16 3 endocrine/metabolic brown 16, 1 4, 1 4, 0 4, 0 4, 0 -0.483 0.869 0.578 0.238 0.617 0.027 2.22 -0.45 195 0.998 0.001 0.638 0.413 0.514 -2.45 447 0.996 0.002 0.0863 8.14e-05 718 -0.081 660 1 0 0.922 0.00111 7.24 PRS_PLINK_1e.06 TRUE 249 Secondary diabetes mellitus Both 7 5 3 endocrine/metabolic brown 5, 7 2, 1 1, 4 1, 2 1, 0 -0.512 1.05 0.627 0.203 0.6 0.0446 6.64 0.0632 1210 1 0 1.07 1.09 2230 -0.0405 98.9 1 0 0.96 0.785 1.15 -1.17 1810 0.999 0 0.309 0.00662 786 PRS_PLINK_1e.06 TRUE 250 Diabetes mellitus Both 32 29 3 endocrine/metabolic brown 29, 32 8, 10 7, 6 7, 8 7, 7 -1.19 0.573 0.0384 1.416 0.305 0.0359 0.846 0.337 1.33 0.8 0.097 1.4 0.0663 34.9 -1.01 1.18 0.392 0.407 0.365 0.0277 3.19 -1.48 1.26 0.242 0.616 0.228 1.25e-06 2.16 PRS_PLINK_1e.06 TRUE 250.1 Type 1 diabetes Both 29 8 3 endocrine/metabolic brown 8, 29 2, 12 2, 2 2, 6 2, 8 -0.523 0.627 0.404 0.393 0.593 0.132 2.08 0.772 2.6 0.767 0.115 2.16 0.00748 1390 -0.512 1.52 0.737 0.133 0.599 0.0137 16.1 -1.68 1.69 0.319 0.496 0.186 0.00042 22.3 PRS_PLINK_1e.06 TRUE 250.11 Type 1 diabetes with ketoacidosis Both 6 1 3 endocrine/metabolic brown 1, 6 -0.0309 570 1 0 0.97 0.594 1.36 PRS_PLINK_1e.06 TRUE 250.12 Type 1 diabetes with renal manifestations Both 17 3 3 endocrine/metabolic brown 3, 17 1, 7 1, 1 0, 1 1, 7 -0.363 0.895 0.685 0.165 0.695 0.0286 17.5 0.833 42.5 0.984 0.007 2.3 2.34 239 0.224 232 0.999 0 1.25 0.483 0.306 -0.608 1.85 0.743 0.129 0.544 0.00187 279 PRS_PLINK_1e.06 TRUE 250.13 Type 1 diabetes with ophthalmic manifestations Both 21 4 3 endocrine/metabolic brown 4, 21 1, 10 1, 2 1, 4 1, 4 -0.393 0.716 0.583 0.235 0.675 0.0376 10.6 -0.697 2.59 0.788 0.103 0.498 0.00268 29.4 -1.1 2.1 0.601 0.221 0.334 0.00158 299 0.984 6.18 0.873 0.059 2.68 4.46e-07 7.7e+07 PRS_PLINK_1e.06 TRUE 250.14 Type 1 diabetes with neurological manifestations Both 22 4 3 endocrine/metabolic brown 4, 22 1, 9 1, 1 1, 1 1, 10 -0.36 0.864 0.677 0.17 0.698 0.0409 10.1 -0.11 3.96 0.978 0.01 0.896 0.000428 1230 -1.33 3.94 0.735 0.134 0.263 0.000363 84.5 0.00773 1.78 0.997 0.002 1.01 0.00149 209 PRS_PLINK_1e.06 TRUE 250.15 Diabetes type 1 with peripheral circulatory disorders Both 4 1 3 endocrine/metabolic brown 1, 4 -0.229 2140 1 0 0.795 0.46 1.96 PRS_PLINK_1e.06 TRUE 250.2 Type 2 diabetes Both 30 26 3 endocrine/metabolic brown 26, 30 7, 7 6, 8 6, 7 7, 7 -0.969 0.546 0.076 1.119 0.379 0.0649 1.05 0.533 1.44 0.711 0.148 1.7 0.109 54.9 -0.736 1.27 0.561 0.251 0.479 0.0382 5.9 -1.43 1.34 0.284 0.546 0.238 0.00423 2.44 PRS_PLINK_1e.06 TRUE 250.21 Type 2 diabetes with ketoacidosis Both 6 0 3 endocrine/metabolic brown 0, 6 PRS_PLINK_1e.06 TRUE 250.22 Type 2 diabetes with renal manifestations Both 4 6 3 endocrine/metabolic brown 6, 4 2, 1 1, 0 1, 1 2, 2 -8.58e-15 2.52 1 0 1 0.0242 41.7 -8.85 7.52e+08 1 0 0.000143 2.88e-25 5.33e+08 3.24 7570 1 0 25.5 0.000105 447000 0.255 4890 1 0 1.29 0.326 1.66 PRS_PLINK_1e.06 TRUE 250.23 Type 2 diabetes with ophthalmic manifestations Both 19 7 3 endocrine/metabolic brown 7, 19 2, 2 2, 9 1, 0 2, 8 -0.385 0.718 0.592 0.228 0.68 0.107 4.6 -0.661 8.91 0.941 0.026 0.516 9.98e-08 732000 -0.54 9660 1 0 0.583 0.121 5.75 -0.55 1.83 0.764 0.117 0.577 0.00642 9.33 PRS_PLINK_1e.06 TRUE 250.24 Type 2 diabetes with neurological manifestations Both 18 10 3 endocrine/metabolic brown 10, 18 3, 9 2, 4 2, 1 3, 3 -0.152 0.689 0.825 0.083 0.859 0.134 9.94 -0.29 2.08 0.889 0.051 0.748 0.00379 118 0.333 3.53 0.925 0.034 1.4 0.000265 387 -0.711 1.58 0.653 0.185 0.491 0.0109 13.6 PRS_PLINK_1e.06 TRUE 250.25 Diabetes type 2 with peripheral circulatory disorders Both 2 3 3 endocrine/metabolic brown 3, 2 1, 0 1, 1 0, 1 1, 0 -2.94e-05 4240 1 0 1 0.462 3.09 -0.0163 243 1 0 0.984 0.85 1.07 -0.00259 30.1 1 0 0.997 0.951 1.05 PRS_PLINK_1e.06 TRUE 250.3 Insulin pump user Both 21 13 3 endocrine/metabolic brown 13, 21 4, 6 3, 6 3, 4 3, 5 -0.749 0.608 0.218 0.662 0.473 0.109 1.44 -0.306 1.88 0.871 0.06 0.737 0.00185 20 -0.358 1.43 0.802 0.096 0.699 0.061 29.3 -1.19 1.86 0.524 0.281 0.306 2.88e-06 6.69 PRS_PLINK_1e.06 TRUE 250.4 Abnormal glucose Both 29 27 3 endocrine/metabolic brown 27, 29 7, 7 7, 6 6, 8 7, 7 -0.71 0.57 0.213 0.672 0.492 0.0841 1.53 0.423 1.54 0.783 0.106 1.53 0.0588 20800 -0.405 1.31 0.758 0.121 0.667 0.0422 14.8 -0.661 1.32 0.618 0.209 0.516 0.00389 17.6 PRS_PLINK_1e.06 TRUE 250.41 Impaired fasting glucose Both 8 15 3 endocrine/metabolic brown 15, 8 4, 1 4, 4 3, 2 4, 1 0.0647 0.874 0.941 0.026 1.07 0.0548 11.6 -0.134 2.75 0.961 0.017 0.875 0.0141 720 -2.4e-13 26.2 1 0 1 0.000717 1.12 1.38 253 0.996 0.002 3.99 3.44e-07 1.41e+08 PRS_PLINK_1e.06 TRUE 250.42 Other abnormal glucose Both 29 27 3 endocrine/metabolic brown 27, 29 7, 7 7, 6 6, 8 7, 7 -0.71 0.57 0.213 0.672 0.492 0.0841 1.53 0.423 1.54 0.783 0.106 1.53 0.0588 20800 -0.405 1.31 0.758 0.121 0.667 0.0422 14.8 -0.661 1.32 0.618 0.209 0.516 0.00389 17.6 PRS_PLINK_1e.06 TRUE 250.6 Polyneuropathy in diabetes Both 22 7 3 endocrine/metabolic brown 7, 22 2, 11 2, 5 1, 2 2, 3 -0.183 0.601 0.761 0.119 0.833 0.169 7.69 0.384 2.09 0.854 0.069 1.47 0.0286 255 0.0485 2.29 0.983 0.007 1.05 0.000659 11800 -0.236 2.85 0.934 0.03 0.79 0.000494 3560 PRS_PLINK_1e.06 TRUE 250.7 Diabetic retinopathy Both 21 10 3 endocrine/metabolic brown 10, 21 2, 1 2, 11 2, 2 3, 7 0.0177 0.49 0.971 0.013 1.02 0.408 2.38 3.36 4.1 0.411 0.386 28.9 0.0447 283000 0.177 256 0.999 0 1.19 0.694 3.01 5.99 12.7 0.636 0.196 398 3.52e-07 4.02e+13 PRS_PLINK_1e.06 TRUE 251 Other disorders of pancreatic internal secretion Both 10 16 3 endocrine/metabolic brown 16, 10 4, 4 4, 0 4, 3 4, 2 -1.25 0.838 0.135 0.869 0.286 0.072 1.13 -1.75 2.89 0.544 0.264 0.173 0.000308 7.8 -0.171 2.2 0.938 0.028 0.843 0.00668 204 -0.759 2.29 0.74 0.131 0.468 0.000102 11.1 PRS_PLINK_1e.06 TRUE 251.1 Hypoglycemia Both 11 5 3 endocrine/metabolic brown 5, 11 2, 5 1, 0 1, 0 1, 5 -0.523 0.902 0.562 0.25 0.593 0.033 5.64 -0.0593 471 1 0 0.942 0.387 1.46 -0.393 7390 1 0 0.675 0.626 9.54 -0.0448 1.85 0.981 0.008 0.956 0.0175 33.3 PRS_PLINK_1e.06 TRUE 252 Disorders of parathyroid gland Both 2 21 3 endocrine/metabolic brown 21, 2 6, 0 5, 1 5, 1 5, 0 0.28 1.08 0.795 0.1 1.32 0.0542 137 0.0182 5.07 0.997 0.001 1.02 7.21e-05 446000 0.495 3.21 0.877 0.057 1.64 0.000209 506 PRS_PLINK_1e.06 TRUE 252.1 Hyperparathyroidism Both 2 21 3 endocrine/metabolic brown 21, 2 6, 0 5, 1 5, 1 5, 0 0.28 1.08 0.795 0.1 1.32 0.0542 137 0.0182 5.07 0.997 0.001 1.02 7.21e-05 446000 0.495 3.21 0.877 0.057 1.64 0.000209 506 PRS_PLINK_1e.06 TRUE 252.2 Hypoparathyroidism Both 0 5 3 endocrine/metabolic brown 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 253 Disorders of the pituitary gland and its hypothalamic control Both 2 14 3 endocrine/metabolic brown 14, 2 4, 1 3, 1 3, 0 4, 0 0.398 1.17 0.733 0.135 1.49 0.144 28.8 0.878 224 0.997 0.001 2.41 0.0573 0.718 0.38 411 0.999 0 1.46 0.00413 8.19 -0.119 51 0.998 0.001 0.888 0.00232 165 PRS_PLINK_1e.06 TRUE 253.1 Pituitary hyperfunction Both 0 6 3 endocrine/metabolic brown 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 253.11 Acromegaly and gigantism Both 0 1 3 endocrine/metabolic brown 1, 0 PRS_PLINK_1e.06 TRUE 253.2 Pituitary hypofunction Both 1 7 3 endocrine/metabolic brown 7, 1 2, 1 2, 0 1, 0 2, 0 0.00181 47.1 1 0 1 0.899 1.17 -0.325 18800 1 0 0.723 0.169 8.05 0.176 24100 1 0 1.19 0.136 15.8 -0.0694 2560 1 0 0.933 0.409 2.12 PRS_PLINK_1e.06 TRUE 253.3 Diabetes insipidus Both 0 3 3 endocrine/metabolic brown 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 253.4 Anterior pituitary disorders Both 0 4 3 endocrine/metabolic brown 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 253.7 Other disorders of neurohypophysis Both 0 2 3 endocrine/metabolic brown 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 255 Disorders of adrenal glands Both 0 20 3 endocrine/metabolic brown 20, 0 5 5 5 5 PRS_PLINK_1e.06 TRUE 255.1 Adrenal hyperfunction Both 0 3 3 endocrine/metabolic brown 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 255.11 Cushing's syndrome Both 0 1 3 endocrine/metabolic brown 1, 0 PRS_PLINK_1e.06 TRUE 255.12 Hyperaldosteronism Both 0 1 3 endocrine/metabolic brown 1, 0 PRS_PLINK_1e.06 TRUE 255.2 Adrenal hypofunction Both 0 7 3 endocrine/metabolic brown 7, 0 2 2 1 2 PRS_PLINK_1e.06 TRUE 255.21 Glucocorticoid deficiency Both 0 7 3 endocrine/metabolic brown 7, 0 2 2 1 2 PRS_PLINK_1e.06 TRUE 256 Ovarian dysfunction Female 2 11 3 endocrine/metabolic brown 11, 2 3, 0 3, 1 2, 1 3, 0 0.013 0.858 0.988 0.005 1.01 0.266 4.02 0.204 114 0.999 0.001 1.23 0.514 2.56 0.0432 174 1 0 1.04 0.842 1.51 PRS_PLINK_1e.06 TRUE 256.4 Polycystic ovaries Female 1 6 3 endocrine/metabolic brown 6, 1 2, 0 1, 1 1, 0 2, 0 0.557 1380 1 0 1.75 3.68 10.1 0.885 47.3 0.985 0.007 2.42 0.00203 1750 PRS_PLINK_1e.06 TRUE 257 Testicular dysfunction Male 5 10 3 endocrine/metabolic brown 10, 5 3, 2 2, 2 2, 0 3, 1 0.0733 1.35 0.957 0.019 1.08 0.0936 34.8 1.39 65.7 0.983 0.007 4.02 1.91e-06 9790000 0.00941 194 1 0 1.01 0.901 1.51 -0.208 2.68 0.938 0.028 0.812 0.00481 32.7 PRS_PLINK_1e.06 TRUE 257.1 Testicular hypofunction Male 5 11 3 endocrine/metabolic brown 11, 5 3, 2 3, 2 2, 0 3, 1 -0.0807 1.35 0.952 0.021 0.922 0.000702 18.9 -0.462 52.4 0.993 0.003 0.63 1.8e-07 2400000 0.00941 194 1 0 1.01 0.901 1.51 -0.208 2.68 0.938 0.028 0.812 0.00481 32.7 PRS_PLINK_1e.06 TRUE 258 Iatrogenic endocrine disorders Both 0 1 3 endocrine/metabolic brown 1, 0 PRS_PLINK_1e.06 TRUE 259 Other endocrine disorders Both 2 15 3 endocrine/metabolic brown 15, 2 4, 1 4, 0 3, 1 4, 0 -0.775 0.917 0.398 0.4 0.461 0.0697 1.89 -0.0364 2370 1 0 0.964 0.432 1.47 -1.41 121 0.991 0.004 0.244 0.209 0.343 0.042 11.8 0.997 0.001 1.04 0.907 8.08 PRS_PLINK_1e.06 TRUE 260 Protein-calorie malnutrition Both 2 22 3 endocrine/metabolic brown 22, 2 5, 0 5, 0 5, 2 6, 0 0.161 0.738 0.828 0.082 1.17 0.186 23.6 -1.53 5.87 0.794 0.1 0.215 2.39e-08 1410 PRS_PLINK_1e.06 TRUE 260.2 severe protein-calorie malnutrition Both 1 12 3 endocrine/metabolic brown 12, 1 3, 0 3, 0 3, 1 3, 0 0.268 0.955 0.779 0.108 1.31 0.249 29.9 0.0148 33.4 1 0 1.01 0.723 1.17 PRS_PLINK_1e.06 TRUE 260.22 Nutritional marasmus Both 1 4 3 endocrine/metabolic brown 4, 1 1, 0 1, 1 1, 0 1, 0 1.04 8370 1 0 2.82 0.337 6.38 -0.00135 276 1 0 0.999 0.985 1.01 PRS_PLINK_1e.06 TRUE 260.3 Adult failure to thrive Both 1 3 3 endocrine/metabolic brown 3, 1 1, 0 1, 1 1, 0 1, 0 -0.898 1030 0.999 0 0.408 0.0303 4.05 -0.297 2460 1 0 0.743 0.736 1.36 PRS_PLINK_1e.06 TRUE 260.6 Anorexia Both 1 4 3 endocrine/metabolic brown 4, 1 1, 0 1, 0 1, 0 1, 1 5.09 1.06e+09 1 0 163 2.48e-34 1.66e+37 -0.00873 38.7 1 0 0.991 0.921 1.07 PRS_PLINK_1e.06 TRUE 260.7 Polyphagia Both 0 2 3 endocrine/metabolic brown 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 261 Vitamin deficiency Both 20 37 3 endocrine/metabolic brown 37, 20 9, 6 9, 3 9, 6 9, 5 -0.125 0.302 0.678 0.169 0.882 0.503 1.53 -3.52 2.28 0.122 0.913 0.0296 5.36e-06 1.03 0.0262 0.918 0.977 0.01 1.03 0.196 5.73 -0.6 0.959 0.532 0.274 0.549 0.088 2.79 PRS_PLINK_1e.06 TRUE 261.1 Vitamin A deficiency Both 2 0 3 endocrine/metabolic brown 0, 2 PRS_PLINK_1e.06 TRUE 261.2 Vitamin B-complex deficiencies Both 1 7 3 endocrine/metabolic brown 7, 1 2, 0 2, 0 1, 0 2, 1 -0.704 133 0.996 0.002 0.495 0.0299 8.18 -0.158 2090 1 0 0.854 0.0188 2.58 PRS_PLINK_1e.06 TRUE 261.4 Vitamin D deficiency Both 20 36 3 endocrine/metabolic brown 36, 20 8, 6 9, 3 9, 6 9, 5 -0.154 0.302 0.612 0.213 0.858 0.488 1.49 -5.35 2.87 0.0626 1.204 0.00474 3.27e-06 0.653 -0.0988 0.982 0.92 0.036 0.906 0.155 5.83 -0.752 1 0.454 0.343 0.471 0.0677 2.52 PRS_PLINK_1e.06 TRUE 262 Mineral deficiency NEC Both 7 13 3 endocrine/metabolic brown 13, 7 4, 2 3, 2 3, 1 3, 2 0.11 0.987 0.911 0.04 1.12 0.185 187 2.13 3.91 0.585 0.233 8.43 0.0637 10.6 0.992 2.51 0.693 0.159 2.7 0.0642 138 0.165 3.85 0.966 0.015 1.18 0.911 1.43 PRS_PLINK_1e.06 TRUE 263 Other nutritional deficiency Both 4 19 3 endocrine/metabolic brown 19, 4 5, 0 5, 1 4, 3 5, 0 -0.831 1.08 0.441 0.355 0.435 0.000462 12.5 -2.13e-10 28.8 1 0 1 0.00258 427 0.498 2.07 0.81 0.091 1.65 0.015 68.5 PRS_PLINK_1e.06 TRUE 264 Lack of normal physiological development Both 1 2 3 endocrine/metabolic brown 2, 1 1, 0 1, 1 1, 0 1, 1 0.0241 3530 1 0 1.02 0.0963 1.24 -0.00068 195 1 0 0.999 0.984 1.02 PRS_PLINK_1e.06 TRUE 264.2 Failure to thrive (childhood) Both 1 4 3 endocrine/metabolic brown 4, 1 1, 0 1, 1 1, 0 1, 0 -0.07 1060 1 0 0.932 0.684 1.19 -0.000811 118 1 0 0.999 0.991 1.01 PRS_PLINK_1e.06 TRUE 264.9 Lack of normal physiological development, unspecified Both 1 1 3 endocrine/metabolic brown 1, 1 0.00421 92.8 1 0 1 0.199 1.11 PRS_PLINK_1e.06 TRUE 269 Proteinuria Both 9 30 3 endocrine/metabolic brown 30, 9 7, 3 7, 0 7, 2 8, 4 0.419 0.492 0.394 0.404 1.52 0.656 3.94 -4.4 3.72 0.237 0.625 0.0123 4.68e-08 2.29 0.394 1.6 0.806 0.094 1.48 0.0831 31.7 -1.22 2.1 0.564 0.249 0.297 0.00203 9.24 PRS_PLINK_1e.06 TRUE 270 Disorders of protein plasma/amino-acid transport and metabolism Both 4 10 3 endocrine/metabolic brown 10, 4 3, 1 2, 1 2, 0 3, 2 0.264 1.68 0.875 0.058 1.3 0.0238 80.9 0.0304 2910 1 0 1.03 0.413 2.6 0.307 16200 1 0 1.36 0.343 3.02 0.0271 4320000 1 0 1.03 0.0673 15.1 PRS_PLINK_1e.06 TRUE 270.1 Disturbances of amino-acid transport Both 1 1 3 endocrine/metabolic brown 1, 1 -0.0012 120 1 0 0.999 0.981 1.04 PRS_PLINK_1e.06 TRUE 270.11 Disturbances of sulphur-bearing amino-acid metabolism Both 1 0 3 endocrine/metabolic brown 0, 1 PRS_PLINK_1e.06 TRUE 270.2 Disorders of amino-acid metabolism Both 0 4 3 endocrine/metabolic brown 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 270.3 Disorders of plasma protein metabolism Both 3 10 3 endocrine/metabolic brown 10, 3 3, 1 2, 1 2, 0 3, 1 -0.204 2.19 0.926 0.034 0.815 0.0105 18.5 0.0304 2910 1 0 1.03 0.413 2.6 0.00597 515 1 0 1.01 0.00295 1.29 -0.0337 6310 1 0 0.967 0.273 4.03 PRS_PLINK_1e.06 TRUE 270.32 Paraproteinemia Both 2 6 3 endocrine/metabolic brown 6, 2 2, 1 1, 1 1, 0 2, 0 -0.12 1200 1 0 0.887 0.861 1.69 0.0248 3440 1 0 1.03 0.911 1.11 -0.98 4.63e+08 1 0 0.375 0.000614 30.2 0.15 6950 1 0 1.16 0.223 1.27 PRS_PLINK_1e.06 TRUE 270.34 Alpha-1-antitrypsin deficiency Both 0 3 3 endocrine/metabolic brown 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 270.38 Other specified disorders of plasma protein metabolism Both 1 5 3 endocrine/metabolic brown 5, 1 2, 0 1, 0 1, 0 1, 1 0.252 892 1 0 1.29 0.141 348 -0.0365 34.4 0.999 0 0.964 0.853 1.15 PRS_PLINK_1e.06 TRUE 271 Disorders of carbohydrate transport and metabolism Both 2 36 3 endocrine/metabolic brown 36, 2 9, 1 9, 0 9, 1 9, 0 -0.637 0.651 0.328 0.485 0.529 0.037 2.09 0.31 1.98 0.876 0.058 1.36 0.0394 411 -0.509 1.39 0.715 0.146 0.601 0.00547 8.87 -0.57 2 0.776 0.11 0.565 0.00488 44.7 PRS_PLINK_1e.06 TRUE 271.3 Intestinal disaccharidase deficiencies and disaccharide malabsorption Both 1 33 3 endocrine/metabolic brown 33, 1 9, 0 8, 0 8, 1 8, 0 -0.0993 0.805 0.902 0.045 0.905 0.0627 16.8 0.47 1.41 0.74 0.131 1.6 0.031 194 PRS_PLINK_1e.06 TRUE 271.9 Other disorders of carbohydrate transport and metabolism Both 1 3 3 endocrine/metabolic brown 3, 1 1, 1 1, 0 1, 0 1, 1 0.0856 1870 1 0 1.09 0.44 1.22 0.00759 42.8 1 0 1.01 0.932 1.13 0.00626 39.9 1 0 1.01 0.947 1.13 PRS_PLINK_1e.06 TRUE 272 Disorders of lipoid metabolism Both 33 28 3 endocrine/metabolic brown 28, 33 7, 8 7, 9 7, 11 7, 4 -0.323 0.328 0.325 0.488 0.724 0.384 1.31 -0.95 1.63 0.561 0.251 0.387 0.000671 11.8 0.215 0.966 0.824 0.084 1.24 0.156 8.5 -1.13 1.31 0.388 0.411 0.323 0.00291 3 PRS_PLINK_1e.06 TRUE 272.1 Hyperlipidemia Both 33 28 3 endocrine/metabolic brown 28, 33 7, 8 7, 9 7, 11 7, 4 -0.323 0.328 0.325 0.488 0.724 0.384 1.31 -0.95 1.63 0.561 0.251 0.387 0.000671 11.8 0.215 0.966 0.824 0.084 1.24 0.156 8.5 -1.13 1.31 0.388 0.411 0.323 0.00291 3 PRS_PLINK_1e.06 TRUE 272.11 Hypercholesterolemia Both 16 19 3 endocrine/metabolic brown 19, 16 5, 5 5, 3 4, 6 5, 2 -0.204 0.501 0.684 0.165 0.816 0.31 1.9 -0.318 1.39 0.819 0.087 0.728 0.0113 7.8 0.585 1.3 0.653 0.185 1.8 0.173 15 -1.01 1.58 0.523 0.281 0.364 0.0133 3.59 PRS_PLINK_1e.06 TRUE 272.12 Hyperglyceridemia Both 5 7 3 endocrine/metabolic brown 7, 5 2, 4 2, 0 1, 0 2, 1 -1.53 1.8 0.394 0.404 0.216 0.00339 2.55 -2.54 1130 0.998 0.001 0.0792 0.0648 0.165 -0.00294 63.2 1 0 0.997 0.364 3.93 0.124 1.4e+08 1 0 1.13 6.68e-08 64200 PRS_PLINK_1e.06 TRUE 272.13 Mixed hyperlipidemia Both 14 17 3 endocrine/metabolic brown 17, 14 5, 3 4, 6 4, 4 4, 1 -0.272 0.507 0.592 0.228 0.762 0.27 1.89 1.67 1.67 0.318 0.497 5.31 0.166 517 -0.473 1.5 0.753 0.123 0.623 0.0276 13 -0.678 1.77 0.702 0.153 0.508 0.013 8.26 PRS_PLINK_1e.06 TRUE 272.9 Unspecified disorder of lipoid metabolism Both 0 3 3 endocrine/metabolic brown 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 274 Gout and other crystal arthropathies Both 2 27 3 endocrine/metabolic brown 27, 2 7, 1 7, 0 6, 0 7, 0 -0.661 0.609 0.278 0.556 0.516 0.111 1.51 0.73 2.94 0.804 0.095 2.08 0.0186 8870 -0.517 3.21 0.872 0.059 0.597 0.00089 745 -0.372 3.45 0.914 0.039 0.689 0.00149 632 PRS_PLINK_1e.06 TRUE 274.1 Gout Both 2 27 3 endocrine/metabolic brown 27, 2 7, 1 7, 0 6, 0 7, 0 -0.661 0.609 0.278 0.556 0.516 0.111 1.51 0.73 2.94 0.804 0.095 2.08 0.0186 8870 -0.517 3.21 0.872 0.059 0.597 0.00089 745 -0.372 3.45 0.914 0.039 0.689 0.00149 632 PRS_PLINK_1e.06 TRUE 274.11 Gouty arthropathy Both 1 21 3 endocrine/metabolic brown 21, 1 6, 0 5, 0 5, 0 5, 0 -0.176 0.783 0.823 0.085 0.839 0.139 8.27 PRS_PLINK_1e.06 TRUE 274.2 Crystal arthropathies Both 0 2 3 endocrine/metabolic brown 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 274.21 Chondrocalcinosis Both 0 2 3 endocrine/metabolic brown 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 275 Disorders of mineral metabolism Both 7 47 3 endocrine/metabolic brown 47, 7 12, 1 12, 2 11, 1 12, 2 0.197 0.478 0.681 0.167 1.22 0.486 3.37 0.358 1.73 0.836 0.078 1.43 0.0312 560 0.216 1.32 0.87 0.061 1.24 0.063 137 0.879 1.35 0.515 0.288 2.41 0.187 3560 PRS_PLINK_1e.06 TRUE 275.1 Disorders of iron metabolism Both 0 4 4 hematopoietic darkorange1 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 275.11 Hereditary hemochromatosis Both 0 3 4 hematopoietic darkorange1 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 275.2 Disorders of copper metabolism Both 0 2 3 endocrine/metabolic brown 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 275.3 Disorders of magnesium metabolism Both 2 19 3 endocrine/metabolic brown 19, 2 5, 0 5, 0 4, 0 5, 1 -0.316 0.81 0.696 0.157 0.729 0.0348 2.9 -1.13e-05 2.84 1 0 1 0.00985 30000 PRS_PLINK_1e.06 TRUE 275.5 Disorders of calcium/phosphorus metabolism Both 4 40 3 endocrine/metabolic brown 40, 4 10, 0 10, 2 10, 1 10, 1 2.09 1.36 0.125 0.902 8.08 0.615 1120 0.716 1.79 0.69 0.161 2.05 0.0155 456 0.879 1.61 0.585 0.233 2.41 0.111 293 0.174 1.63 0.915 0.039 1.19 0.00611 52.1 PRS_PLINK_1e.06 TRUE 275.51 Hypocalcemia Both 0 9 3 endocrine/metabolic brown 9, 0 3 2 2 2 PRS_PLINK_1e.06 TRUE 275.53 Disorders of phosphorus metabolism Both 1 14 3 endocrine/metabolic brown 14, 1 4, 0 3, 0 3, 1 4, 0 0.314 1.14 0.784 0.106 1.37 0.189 42.4 0.454 587 0.999 0 1.58 0.047 31.7 PRS_PLINK_1e.06 TRUE 275.6 Hypercalcemia Both 4 27 3 endocrine/metabolic brown 27, 4 7, 1 7, 1 6, 1 7, 1 -0.0253 0.679 0.97 0.013 0.975 0.163 60.4 0.564 2.71 0.835 0.078 1.76 0.0055 1410 2.19 2.9 0.45 0.346 8.89 0.0816 11200 -0.728 1.82 0.689 0.162 0.483 0.00254 14.7 PRS_PLINK_1e.06 TRUE 276 Disorders of fluid, electrolyte, and acid-base balance Both 15 47 3 endocrine/metabolic brown 47, 15 11, 0 12, 5 11, 3 12, 7 0.395 0.357 0.267 0.573 1.48 0.786 3.11 3.34 2.3 0.146 0.836 28.4 0.743 69800 1.75 1.58 0.268 0.572 5.78 0.404 2250 1.9 1.29 0.14 0.853 6.68 0.848 1550 PRS_PLINK_1e.06 TRUE 276.1 Electrolyte imbalance Both 11 40 3 endocrine/metabolic brown 40, 11 9, 0 10, 2 10, 2 10, 7 0.624 0.445 0.161 0.794 1.87 0.865 5.21 -0.226 2.35 0.924 0.035 0.798 0.00444 3220 1.54 1.98 0.437 0.36 4.67 0.178 19200 1.5 1.3 0.247 0.607 4.49 0.573 8190 PRS_PLINK_1e.06 TRUE 276.11 Hyperosmolality and/or hypernatremia Both 0 7 3 endocrine/metabolic brown 7, 0 2 2 1 2 PRS_PLINK_1e.06 TRUE 276.12 Hyposmolality and/or hyponatremia Both 4 25 3 endocrine/metabolic brown 25, 4 6, 0 6, 0 6, 1 6, 3 0.892 0.706 0.206 0.685 2.44 0.641 153 1.22 2.48 0.622 0.206 3.4 0.082 23200 1.23 3.58 0.731 0.136 3.43 0.0217 750000 PRS_PLINK_1e.06 TRUE 276.13 Hyperpotassemia Both 3 27 3 endocrine/metabolic brown 27, 3 7, 0 7, 1 6, 1 7, 1 0.0225 0.654 0.973 0.012 1.02 0.212 5.21 -0.161 4.32 0.97 0.013 0.851 0.000199 45500 0.948 3.22 0.768 0.114 2.58 0.00493 1350 0.329 1.54 0.831 0.08 1.39 0.032 61.3 PRS_PLINK_1e.06 TRUE 276.14 Hypopotassemia Both 2 29 3 endocrine/metabolic brown 29, 2 7, 0 7, 1 7, 0 7, 1 -0.0516 0.609 0.932 0.03 0.95 0.0317 4.38 -0.0149 149 1 0 0.985 0.665 1.25 0.627 2.42 0.795 0.099 1.87 0.0125 893 PRS_PLINK_1e.06 TRUE 276.4 Acid-base balance disorder Both 2 22 3 endocrine/metabolic brown 22, 2 6, 0 5, 1 5, 0 6, 1 -0.356 0.655 0.587 0.231 0.7 0.114 2.52 1.34 3.39 0.692 0.16 3.82 0.0331 1270 0.25 1.65 0.88 0.055 1.28 0.0639 62.1 PRS_PLINK_1e.06 TRUE 276.41 Acidosis Both 2 20 3 endocrine/metabolic brown 20, 2 5, 0 5, 1 5, 0 5, 1 -0.216 0.606 0.722 0.141 0.806 0.172 3 5.34 7.32 0.465 0.332 209 0.00747 3.57e+08 -0.487 6.26 0.938 0.028 0.614 2.86e-06 337000 PRS_PLINK_1e.06 TRUE 276.42 Alkalosis Both 0 6 3 endocrine/metabolic brown 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 276.5 Hypovolemia Both 6 39 3 endocrine/metabolic brown 39, 6 9, 0 10, 2 9, 1 10, 3 0.205 0.467 0.66 0.18 1.23 0.441 4.69 0.578 1.73 0.739 0.132 1.78 0.0871 10600 0.429 1.73 0.804 0.094 1.54 0.0702 996 0.96 1.28 0.453 0.344 2.61 0.186 127 PRS_PLINK_1e.06 TRUE 276.6 Fluid overload Both 0 16 3 endocrine/metabolic brown 16, 0 4 4 4 4 PRS_PLINK_1e.06 TRUE 276.8 Polydipsia Both 0 3 3 endocrine/metabolic brown 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 277 Other disorders of metabolism Both 9 43 3 endocrine/metabolic brown 43, 9 10, 1 11, 4 10, 4 11, 0 0.164 0.417 0.694 0.159 1.18 0.548 3.07 0.65 1.63 0.69 0.161 1.92 0.109 912 0.775 1.18 0.512 0.291 2.17 0.309 700 0.126 1.68 0.94 0.027 1.13 0.0173 64 PRS_PLINK_1e.06 TRUE 277.2 Other disorders of purine and pyrimidine metabolism Both 0 18 3 endocrine/metabolic brown 18, 0 5 4 4 5 PRS_PLINK_1e.06 TRUE 277.4 Disorders of bilirubin excretion Both 1 13 3 endocrine/metabolic brown 13, 1 4, 1 3, 0 3, 0 3, 0 -1.02 1.6 0.526 0.279 0.362 0.00503 3.36 0.00416 19.1 1 0 1 0.836 1.11 -0.265 1020 1 0 0.767 0.367 1.33 0.103 974 1 0 1.11 0.858 1.39 PRS_PLINK_1e.06 TRUE 277.5 Other disorders of lipoid metabolism Both 2 21 3 endocrine/metabolic brown 21, 2 5, 0 5, 0 5, 2 5, 0 -0.287 1.04 0.782 0.107 0.751 0.0104 44.7 0.178 2.53 0.944 0.025 1.19 0.00391 119 PRS_PLINK_1e.06 TRUE 277.51 Lipoprotein disorders Both 0 16 3 endocrine/metabolic brown 16, 0 4 4 4 4 PRS_PLINK_1e.06 TRUE 277.7 Dysmetabolic syndrome X Both 4 24 3 endocrine/metabolic brown 24, 4 5, 0 6, 3 6, 0 6, 1 0.147 0.603 0.807 0.093 1.16 0.371 13.3 -0.214 2.74 0.938 0.028 0.808 0.00102 474 0.806 2.29 0.725 0.14 2.24 0.0186 105 PRS_PLINK_1e.06 TRUE 278 Overweight, obesity and other hyperalimentation Both 22 42 3 endocrine/metabolic brown 42, 22 10, 10 10, 6 10, 3 11, 3 -0.49 0.311 0.115 0.938 0.613 0.331 1.07 -0.00977 0.902 0.991 0.004 0.99 0.182 5.21 -1.28 0.991 0.195 0.709 0.277 0.0215 1.52 -1.15 0.925 0.212 0.673 0.315 0.0475 1.51 PRS_PLINK_1e.06 TRUE 278.1 Obesity Both 20 42 3 endocrine/metabolic brown 42, 20 10, 9 10, 5 10, 3 11, 3 -0.434 0.312 0.164 0.785 0.648 0.352 1.14 -0.1 0.922 0.914 0.039 0.905 0.155 4.81 -1.17 0.981 0.231 0.636 0.309 0.0229 1.65 -1.12 0.924 0.224 0.649 0.325 0.0491 1.53 PRS_PLINK_1e.06 TRUE 278.11 Morbid obesity Both 6 38 3 endocrine/metabolic brown 38, 6 9, 1 9, 2 9, 2 10, 1 0.378 0.723 0.601 0.221 1.46 0.333 179 0.316 1.46 0.829 0.081 1.37 0.0842 98.4 2.01 2 0.314 0.504 7.48 0.189 44400 -0.213 1.75 0.903 0.044 0.808 0.00198 101 PRS_PLINK_1e.06 TRUE 278.3 Localized adiposity Both 0 8 3 endocrine/metabolic brown 8, 0 2 2 2 2 PRS_PLINK_1e.06 TRUE 278.4 Abnormal weight gain Both 2 36 3 endocrine/metabolic brown 36, 2 8, 1 9, 1 9, 0 9, 0 -0.666 0.771 0.387 0.412 0.514 0.041 2.27 1.07 2.46 0.664 0.178 2.91 0.0465 1.08e+08 -0.622 1.93 0.747 0.127 0.537 0.00294 25.8 0.558 2.47 0.821 0.086 1.75 1.48e-05 9700 PRS_PLINK_1e.06 TRUE 279 Disorders involving the immune mechanism Both 7 37 3 endocrine/metabolic brown 37, 7 9, 2 9, 3 9, 1 9, 1 -0.125 0.422 0.766 0.116 0.882 0.398 2.11 2.36 2.09 0.258 0.588 10.6 0.253 3030000 -2 2.15 0.354 0.45 0.136 1.84e-06 5.26 -0.927 1.54 0.547 0.262 0.396 0.000522 5.18 PRS_PLINK_1e.06 TRUE 279.1 Immunity deficiency Both 3 15 3 endocrine/metabolic brown 15, 3 4, 2 4, 1 3, 0 4, 0 -0.75 1.02 0.46 0.337 0.472 0.0207 3.25 2.79 6.01 0.643 0.192 16.2 0.00445 677000 6.85 2340 0.998 0.001 942 1.43 2.6e+08 -1.06 10.4 0.919 0.037 0.346 0.327 0.365 PRS_PLINK_1e.06 TRUE 279.11 Deficiency of humoral immunity Both 2 6 3 endocrine/metabolic brown 6, 2 2, 2 1, 0 1, 0 2, 0 -0.776 220 0.997 0.001 0.46 0.152 1.23 -0.355 14800 1 0 0.701 0.387 11 -5.41 37900 1 0 0.00448 7.29e-09 3100000 0.447 3150000 1 0 1.56 0.00153 176 PRS_PLINK_1e.06 TRUE 279.2 Autoimmune disease NEC Both 3 12 3 endocrine/metabolic brown 12, 3 3, 1 3, 2 3, 0 3, 0 -0.173 1.16 0.882 0.055 0.841 0.0444 183 0.293 921 1 0 1.34 0.88 1.99 -0.0113 1620 1 0 0.989 0.368 2.59 -0.00409 965 1 0 0.996 0.302 3.29 PRS_PLINK_1e.06 TRUE 279.7 Other immunological findings Both 12 42 3 endocrine/metabolic brown 42, 12 10, 2 10, 2 10, 4 11, 4 0.259 0.372 0.485 0.314 1.3 0.658 2.79 -0.0928 1.79 0.959 0.018 0.911 0.0254 33.9 1.1 1.38 0.424 0.372 3.02 0.26 107 0.493 1.12 0.659 0.181 1.64 0.235 20.3 PRS_PLINK_1e.06 TRUE 279.8 Other specified disorders involving the immune mechanism Both 3 9 3 endocrine/metabolic brown 9, 3 3, 1 2, 2 2, 0 2, 0 0.0834 1.19 0.944 0.025 1.09 0.12 8.98 0.599 8900000 1 0 1.82 0.00405 1450 0.175 5030 1 0 1.19 0.345 1.89 0.401 9430 1 0 1.49 0.203 8.98 PRS_PLINK_1e.06 TRUE 280 Iron deficiency anemias Both 11 40 4 hematopoietic darkorange1 40, 11 10, 4 10, 2 10, 4 10, 1 -0.253 0.383 0.509 0.293 0.776 0.359 1.58 1.73 1.91 0.364 0.439 5.65 0.222 73700 0.541 1.12 0.63 0.2 1.72 0.203 15.5 -0.114 1.28 0.929 0.032 0.892 0.0586 9.63 PRS_PLINK_1e.06 TRUE 280.1 Iron deficiency anemias, unspecified or not due to blood loss Both 11 39 4 hematopoietic darkorange1 39, 11 10, 4 10, 2 9, 4 10, 1 -0.256 0.384 0.505 0.297 0.774 0.358 1.58 -0.646 1.25 0.606 0.218 0.524 0.0373 4.63 0.405 1.08 0.707 0.151 1.5 0.211 14.2 -0.114 1.28 0.929 0.032 0.892 0.0586 9.63 PRS_PLINK_1e.06 TRUE 280.2 Iron deficiency anemia secondary to blood loss (chronic) Both 3 16 4 hematopoietic darkorange1 16, 3 4, 0 4, 2 4, 1 4, 0 -2.67 2.21 0.228 0.641 0.0694 7.68e-05 2.83 -4.78 604 0.994 0.003 0.0084 0.000476 0.000904 0.51 707 0.999 0 1.67 0.227 7.3 PRS_PLINK_1e.06 TRUE 281 Other deficiency anemia Both 1 6 4 hematopoietic darkorange1 6, 1 2, 1 1, 0 1, 0 2, 0 -1.69 142 0.99 0.004 0.184 4.68e-06 6840 -0.132 2140 1 0 0.876 0.217 3.68 -0.138 4000 1 0 0.871 0.0995 15.2 -0.149 1030 1 0 0.862 0.337 1.35 PRS_PLINK_1e.06 TRUE 281.1 Megaloblastic anemia Both 0 4 4 hematopoietic darkorange1 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 281.11 Pernicious anemia Both 0 3 4 hematopoietic darkorange1 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 281.12 Other vitamin B12 deficiency anemia Both 0 3 4 hematopoietic darkorange1 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 281.9 Deficiency anemias Both 1 1 4 hematopoietic darkorange1 1, 1 0.0195 105 1 0 1.02 0.308 1.73 PRS_PLINK_1e.06 TRUE 282 Hereditary hemolytic anemias Both 1 5 4 hematopoietic darkorange1 5, 1 2, 0 1, 0 1, 0 1, 1 -0.244 5420 1 0 0.784 0.02 14.9 -0.147 122000 1 0 0.864 0.0252 5.14e+12 PRS_PLINK_1e.06 TRUE 282.8 Other hemoglobinopathies Both 1 3 4 hematopoietic darkorange1 3, 1 1, 0 1, 0 1, 1 1, 0 -0.464 15700 1 0 0.629 0.00864 5.61 -0.00572 21.9 1 0 0.994 0.81 1.08 PRS_PLINK_1e.06 TRUE 282.9 Other hereditary hemolytic anemias Both 1 2 4 hematopoietic darkorange1 2, 1 1, 0 1, 1 1, 0 1, 1 -0.00341 83.8 1 0 0.997 0.971 1.08 -0.00334 81.6 1 0 0.997 0.971 1.08 PRS_PLINK_1e.06 TRUE 284 Aplastic anemia Both 1 7 4 hematopoietic darkorange1 7, 1 2, 0 2, 0 1, 1 2, 0 0.0522 13.4 0.997 0.001 1.05 0.709 1.07 -0.0754 6720 1 0 0.927 0.154 5.2 PRS_PLINK_1e.06 TRUE 284.1 Pancytopenia Both 1 6 4 hematopoietic darkorange1 6, 1 2, 0 1, 0 1, 1 2, 0 -0.0681 78 0.999 0 0.934 0.709 1.13 -0.169 8140 1 0 0.844 0.742 5.38 PRS_PLINK_1e.06 TRUE 285 Other anemias Both 13 43 4 hematopoietic darkorange1 43, 13 11, 5 11, 3 10, 4 11, 0 -0.397 0.39 0.308 0.511 0.672 0.3 1.39 -0.922 0.978 0.346 0.461 0.398 0.0554 1.97 0.235 0.993 0.813 0.09 1.26 0.21 8.97 -0.524 1.24 0.672 0.173 0.592 0.0332 6.49 PRS_PLINK_1e.06 TRUE 285.1 Acute posthemorrhagic anemia Both 0 29 4 hematopoietic darkorange1 29, 0 8 7 7 7 PRS_PLINK_1e.06 TRUE 285.2 Anemia of chronic disease Both 1 23 4 hematopoietic darkorange1 23, 1 6, 1 6, 0 5, 0 6, 0 -0.507 0.786 0.519 0.285 0.602 0.0265 3.19 -0.273 2.18 0.9 0.046 0.761 0.0303 935 -1.46 3.55 0.682 0.166 0.233 0.000775 878 -2.01 2.64 0.446 0.351 0.134 0.000209 9.68 PRS_PLINK_1e.06 TRUE 285.21 Anemia in chronic kidney disease Both 0 16 4 hematopoietic darkorange1 16, 0 4 4 4 4 PRS_PLINK_1e.06 TRUE 285.22 Anemia in neoplastic disease Both 0 5 4 hematopoietic darkorange1 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 286 Coagulation defects Both 7 40 4 hematopoietic darkorange1 40, 7 9, 1 10, 0 10, 2 10, 4 0.527 0.551 0.339 0.469 1.69 0.59 8.98 -0.448 1.94 0.817 0.088 0.639 0.000171 81.5 1.03 1.81 0.571 0.243 2.79 0.112 602000 0.71 1.43 0.62 0.207 2.03 0.1 424 PRS_PLINK_1e.06 TRUE 286.1 Congenital coagulation defects Both 0 8 4 hematopoietic darkorange1 8, 0 2 2 2 2 PRS_PLINK_1e.06 TRUE 286.11 Von willebrand's disease Both 0 3 4 hematopoietic darkorange1 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 286.12 Congenital deficiency of other clotting factors (including factor VII) Both 0 4 4 hematopoietic darkorange1 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 286.2 Encounter for long-term (current) use of anticoagulants Both 3 32 4 hematopoietic darkorange1 32, 3 7, 1 8, 1 8, 1 8, 0 -0.26 0.567 0.647 0.189 0.771 0.025 3.03 0.616 2.73 0.822 0.085 1.85 0.0165 1100 -0.0915 1.67 0.956 0.019 0.913 0.0222 62.3 -0.295 1.61 0.854 0.068 0.745 0.00125 27.6 PRS_PLINK_1e.06 TRUE 286.3 Coagulation defects complicating pregnancy or postpartum Female 1 2 4 hematopoietic darkorange1 2, 1 1, 0 0, 1 1, 0 1, 0 -0.698 7650 1 0 0.498 0.264 1.89 -0.00386 132 1 0 0.996 0.966 1.04 PRS_PLINK_1e.06 TRUE 286.4 Acquired coagulation factor deficiency Both 0 3 4 hematopoietic darkorange1 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 286.5 Hemorrhagic disorder due to intrinsic circulating anticoagulants Both 0 4 4 hematopoietic darkorange1 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 286.6 Defibrination syndrome Both 5 37 4 hematopoietic darkorange1 37, 5 9, 0 9, 0 9, 1 9, 4 0.605 0.579 0.296 0.529 1.83 0.562 36.6 0.279 1.93 0.885 0.053 1.32 0.0104 124 0.538 1.84 0.769 0.114 1.71 0.0441 146 PRS_PLINK_1e.06 TRUE 286.7 Other and unspecified coagulation defects Both 6 40 4 hematopoietic darkorange1 40, 6 9, 1 10, 0 10, 1 10, 4 0.433 0.506 0.392 0.406 1.54 0.587 6.94 -0.889 1.67 0.595 0.225 0.411 0.000359 8.3 0.116 1.75 0.947 0.024 1.12 0.0344 654 0.778 1.48 0.599 0.223 2.18 0.0641 1180 PRS_PLINK_1e.06 TRUE 286.8 Hypercoagulable state Both 1 13 4 hematopoietic darkorange1 13, 1 4, 0 3, 0 3, 0 3, 1 -0.0715 1.05 0.946 0.024 0.931 0.0633 7.4 0.527 1170 1 0 1.69 0.155 6.71 PRS_PLINK_1e.06 TRUE 286.81 Primary hypercoagulable state Both 1 11 4 hematopoietic darkorange1 11, 1 3, 0 3, 0 2, 0 3, 1 -0.00842 1.04 0.994 0.003 0.992 0.116 8.17 0.0237 1580 1 0 1.02 0.704 2.14 PRS_PLINK_1e.06 TRUE 286.9 Abnormal coagulation profile Both 2 14 4 hematopoietic darkorange1 14, 2 4, 0 3, 0 3, 1 4, 1 0.467 1.11 0.675 0.171 1.59 0.245 12.8 -0.00843 1190 1 0 0.992 0.472 1.48 0.561 112 0.996 0.002 1.75 9.25e-07 4.9 PRS_PLINK_1e.06 TRUE 287 Purpura and other hemorrhagic conditions Both 3 36 4 hematopoietic darkorange1 36, 3 9, 0 9, 0 9, 3 9, 0 0.0884 0.646 0.891 0.05 1.09 0.207 13.3 0.79 1.48 0.594 0.226 2.2 0.031 752 PRS_PLINK_1e.06 TRUE 287.1 Spontaneous ecchymoses Both 0 3 4 hematopoietic darkorange1 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 287.3 Thrombocytopenia Both 3 33 4 hematopoietic darkorange1 33, 3 9, 0 8, 0 8, 3 8, 0 0.134 0.654 0.837 0.077 1.14 0.205 43.8 0.75 1.35 0.578 0.238 2.12 0.00918 343 PRS_PLINK_1e.06 TRUE 287.31 Primary thrombocytopenia Both 1 5 4 hematopoietic darkorange1 5, 1 2, 0 1, 0 1, 0 1, 1 17.9 5370 0.997 0.001 56700000 1.05e-38 7.19e+47 30.5 8.62e+08 1 0 1.73e+13 2.64e-23 4.73e+54 PRS_PLINK_1e.06 TRUE 287.32 Secondary thrombocytopenia Both 1 10 4 hematopoietic darkorange1 10, 1 3, 0 2, 0 2, 1 3, 0 1.19 1.93 0.536 0.271 3.3 0.264 89.3 0.00484 27.6 1 0 1 0.918 1.33 PRS_PLINK_1e.06 TRUE 287.4 Qualitative platelet defects Both 0 2 4 hematopoietic darkorange1 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 288 Diseases of white blood cells Both 7 51 4 hematopoietic darkorange1 51, 7 12, 1 13, 2 12, 4 13, 0 0.134 0.422 0.75 0.125 1.14 0.502 3.04 1.25 1.52 0.413 0.384 3.48 0.214 7020 0.938 1.2 0.436 0.361 2.56 0.254 37.6 0.206 1.44 0.887 0.052 1.23 0.0144 1620 PRS_PLINK_1e.06 TRUE 288.1 Decreased white blood cell count Both 2 19 4 hematopoietic darkorange1 19, 2 4, 1 5, 1 4, 0 5, 0 0.118 0.716 0.869 0.061 1.13 0.17 40.2 0.332 1660 1 0 1.39 0.57 3.14 0.0715 1280 1 0 1.07 0.73 1.24 -0.457 131 0.997 0.001 0.633 3.19e-06 80000 PRS_PLINK_1e.06 TRUE 288.11 Neutropenia Both 2 17 4 hematopoietic darkorange1 17, 2 4, 1 4, 1 4, 0 4, 0 0.185 0.688 0.788 0.103 1.2 0.336 8.92 0.0173 177 1 0 1.02 0.83 1.58 -1.04 34.6 0.976 0.011 0.353 0.000495 0.391 -8.9e-12 17.1 1 0 1 0.963 11.1 PRS_PLINK_1e.06 TRUE 288.2 Elevated white blood cell count Both 5 47 4 hematopoietic darkorange1 47, 5 11, 1 12, 1 11, 3 12, 0 -0.15 0.451 0.74 0.131 0.861 0.345 2.33 0.694 1.75 0.692 0.16 2 0.043 10300000 0.497 1.37 0.716 0.145 1.64 0.0876 287 0.127 1.51 0.933 0.03 1.14 0.00169 15900 PRS_PLINK_1e.06 TRUE 288.3 Eosinophilia Both 2 0 4 hematopoietic darkorange1 0, 2 PRS_PLINK_1e.06 TRUE 289 Other diseases of blood and blood-forming organs Both 2 26 4 hematopoietic darkorange1 26, 2 6, 0 6, 0 6, 0 7, 2 0.119 0.65 0.855 0.068 1.13 0.311 186 0.232 1.98 0.907 0.042 1.26 0.00656 2330 PRS_PLINK_1e.06 TRUE 289.3 Personal history of diseases of blood and blood-forming organs Both 1 15 4 hematopoietic darkorange1 15, 1 4, 0 4, 0 3, 0 4, 1 0.224 0.807 0.781 0.107 1.25 0.406 65.7 0.378 2150000 1 0 1.46 0.0371 60.1 PRS_PLINK_1e.06 TRUE 289.4 Lymphadenitis Both 5 45 4 hematopoietic darkorange1 45, 5 11, 1 11, 2 11, 1 11, 1 0.0138 0.398 0.972 0.012 1.01 0.466 2.43 1.8 1.81 0.321 0.493 6.04 0.11 102000 0.321 1.78 0.857 0.067 1.38 0.00313 37100 0.00591 1.35 0.997 0.002 1.01 0.0236 22.8 PRS_PLINK_1e.06 TRUE 289.5 Diseases of spleen Both 0 5 4 hematopoietic darkorange1 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 289.8 Polycythemia, secondary Both 1 9 4 hematopoietic darkorange1 9, 1 2, 0 2, 1 2, 0 2, 0 -0.00163 51.2 1 0 0.998 0.294 1.48 -0.592 13300 1 0 0.553 0.254 3.87 PRS_PLINK_1e.06 TRUE 289.9 Abnormality of red blood cells Both 0 8 4 hematopoietic darkorange1 8, 0 2 2 2 2 PRS_PLINK_1e.06 TRUE 290 Delirium dementia and amnestic and other cognitive disorders Both 1 9 5 mental disorders magenta 9, 1 3, 0 2, 0 2, 1 2, 0 0.285 1.72 0.869 0.061 1.33 0.0936 20.8 -0.186 1040 1 0 0.83 0.219 1.51 PRS_PLINK_1e.06 TRUE 290.1 Dementias Both 1 2 5 mental disorders magenta 2, 1 1, 0 1, 1 1, 0 1, 1 -0.433 16400 1 0 0.649 0.376 11.8 -0.272 9960 1 0 0.762 0.65 4.73 PRS_PLINK_1e.06 TRUE 290.11 Alzheimer's disease Both 0 1 5 mental disorders magenta 1, 0 PRS_PLINK_1e.06 TRUE 290.13 Senile dementia Both 1 3 5 mental disorders magenta 3, 1 1, 0 1, 0 1, 1 1, 0 -0.772 8820 1 0 0.462 0.272 6.64 -0.00504 11.8 1 0 0.995 0.921 1.1 PRS_PLINK_1e.06 TRUE 290.2 Delirium due to conditions classified elsewhere Both 0 5 5 mental disorders magenta 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 290.3 Other persistent mental disorders due to conditions classified elsewhere Both 0 10 5 mental disorders magenta 10, 0 3 2 2 3 PRS_PLINK_1e.06 TRUE 291 Other specified nonpsychotic and/or transient mental disorders Both 2 36 5 mental disorders magenta 36, 2 8, 0 9, 1 9, 0 9, 1 0.4 0.597 0.504 0.298 1.49 0.403 45.2 -0.208 1.64 0.899 0.046 0.812 0.00657 209 0.285 1.45 0.844 0.074 1.33 0.063 37.9 PRS_PLINK_1e.06 TRUE 291.1 Transient mental disorders due to conditions classified elsewhere Both 0 4 5 mental disorders magenta 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 291.4 Specific nonpsychotic mental disorders due to brain damage Both 0 9 5 mental disorders magenta 9, 0 3 2 2 2 PRS_PLINK_1e.06 TRUE 291.8 Alteration of consciousness Both 2 27 5 mental disorders magenta 27, 2 6, 0 7, 1 6, 0 7, 1 0.304 0.564 0.59 0.229 1.36 0.137 18.6 0.0972 2.01 0.961 0.017 1.1 0.0291 9630 0.479 2.69 0.859 0.066 1.61 0.0123 681 PRS_PLINK_1e.06 TRUE 292 Neurological disorders Both 8 51 5 mental disorders magenta 51, 8 12, 1 13, 4 12, 1 13, 2 0.106 0.418 0.8 0.097 1.11 0.467 2.86 0.828 1.43 0.563 0.249 2.29 0.208 86.6 0.228 1.22 0.852 0.07 1.26 0.0803 72.7 0.736 1.35 0.585 0.233 2.09 0.117 4840 PRS_PLINK_1e.06 TRUE 292.1 Aphasia/speech disturbance Both 3 20 5 mental disorders magenta 20, 3 5, 1 5, 1 5, 0 5, 1 0.348 1.38 0.801 0.097 1.42 0.0232 1280 -0.921 2.86 0.747 0.126 0.398 0.00119 76.3 -1.97 4.23 0.641 0.193 0.14 0.000133 1510 0.182 7.67 0.981 0.008 1.2 2.59e-07 1.1e+08 PRS_PLINK_1e.06 TRUE 292.11 Aphasia Both 2 0 5 mental disorders magenta 0, 2 PRS_PLINK_1e.06 TRUE 292.12 Symbolic dysfunction Both 1 4 5 mental disorders magenta 4, 1 1, 1 1, 0 1, 0 1, 0 -0.0569 2400 1 0 0.945 0.296 2.89 0.831 75500 1 0 2.3 0.061 36800 0.0248 50.6 1 0 1.03 0.911 1.46 0.00296 26.3 1 0 1 0.969 1.04 PRS_PLINK_1e.06 TRUE 292.2 Mild cognitive impairment Both 1 3 5 mental disorders magenta 3, 1 1, 1 1, 0 1, 0 1, 1 -0.013 1080 1 0 0.987 0.736 1.04 0.00748 38.4 1 0 1.01 0.916 1.11 0.00909 50 1 0 1.01 0.924 1.12 PRS_PLINK_1e.06 TRUE 292.3 Memory loss Both 2 24 5 mental disorders magenta 24, 2 5, 1 6, 0 6, 1 6, 0 0.0379 0.679 0.956 0.02 1.04 0.263 5.67 0.469 2.75 0.865 0.063 1.6 0.0249 2540 2.04 4.01 0.612 0.213 7.65 6.71 8.7 -0.439 2.22 0.843 0.074 0.645 0.00138 44.1 PRS_PLINK_1e.06 TRUE 292.4 Altered mental status Both 3 28 5 mental disorders magenta 28, 3 6, 1 7, 1 7, 0 7, 1 0.138 0.552 0.803 0.095 1.15 0.445 9.71 1.28 1.81 0.477 0.321 3.61 0.232 233 -0.295 1.8 0.87 0.061 0.745 0.0327 300 0.0643 1.46 0.965 0.016 1.07 0.0466 52.6 PRS_PLINK_1e.06 TRUE 292.5 Transient alteration of awareness Both 0 7 5 mental disorders magenta 7, 0 1 2 1 2 PRS_PLINK_1e.06 TRUE 292.6 Hallucinations Both 0 2 5 mental disorders magenta 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 293 Symptoms involving head and neck Both 2 9 5 mental disorders magenta 9, 2 3, 0 2, 2 2, 0 2, 0 0.653 8.34 0.938 0.028 1.92 1.8 2.03 -0.059 792 1 0 0.943 0.395 3.01 PRS_PLINK_1e.06 TRUE 293.1 Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS] Both 4 47 5 mental disorders magenta 47, 4 11, 0 12, 3 11, 1 12, 0 0.00575 0.655 0.993 0.003 1.01 0.186 29.2 0.539 1.63 0.741 0.13 1.71 0.0797 225 0.572 1.47 0.698 0.156 1.77 0.0642 188 PRS_PLINK_1e.06 TRUE 295 Schizophrenia and other psychotic disorders Both 0 7 5 mental disorders magenta 7, 0 2 2 1 2 PRS_PLINK_1e.06 TRUE 295.1 Schizophrenia Both 0 1 5 mental disorders magenta 1, 0 PRS_PLINK_1e.06 TRUE 295.2 Paranoid disorders Both 0 3 5 mental disorders magenta 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 295.3 Psychosis Both 0 7 5 mental disorders magenta 7, 0 2 2 1 2 PRS_PLINK_1e.06 TRUE 296 Mood disorders Both 29 19 5 mental disorders magenta 19, 29 5, 11 5, 5 4, 2 5, 10 -0.0677 0.344 0.844 0.074 0.935 0.491 1.75 -0.923 1.33 0.486 0.313 0.397 0.0025 4.45 -0.601 1.21 0.62 0.208 0.548 0.061 5.37 0.371 1.06 0.725 0.14 1.45 0.228 11.7 PRS_PLINK_1e.06 TRUE 296.1 Bipolar Both 2 13 5 mental disorders magenta 13, 2 4, 2 3, 0 3, 0 3, 0 -0.804 1.16 0.488 0.312 0.448 0.0424 8.4 -0.886 2170000 1 0 0.412 0.0275 9.61 -1.83 4170 1 0 0.16 0.12 0.22 -0.42 4170 1 0 0.657 0.00185 0.741 PRS_PLINK_1e.06 TRUE 296.2 Depression Both 28 19 5 mental disorders magenta 19, 28 5, 11 5, 4 4, 2 5, 10 -0.075 0.344 0.828 0.082 0.928 0.489 1.73 -1.02 1.38 0.459 0.338 0.361 0.00178 4.09 -0.601 1.21 0.62 0.208 0.548 0.061 5.37 0.371 1.06 0.725 0.14 1.45 0.228 11.7 PRS_PLINK_1e.06 TRUE 296.22 Major depressive disorder Both 28 19 5 mental disorders magenta 19, 28 5, 11 5, 4 4, 2 5, 10 -0.075 0.344 0.828 0.082 0.928 0.489 1.73 -1.02 1.38 0.459 0.338 0.361 0.00178 4.09 -0.601 1.21 0.62 0.208 0.548 0.061 5.37 0.371 1.06 0.725 0.14 1.45 0.228 11.7 PRS_PLINK_1e.06 TRUE 297 Suicidal ideation or attempt Both 1 14 5 mental disorders magenta 14, 1 4, 0 3, 1 3, 0 4, 0 0.368 1.14 0.747 0.127 1.45 0.142 31.6 -0.475 5290 1 0 0.622 0.595 1.9 PRS_PLINK_1e.06 TRUE 297.1 Suicidal ideation Both 1 10 5 mental disorders magenta 10, 1 3, 0 2, 1 2, 0 3, 0 0.264 2.31 0.909 0.041 1.3 1.22 1.48 -0.177 4170 1 0 0.838 0.814 1.88 PRS_PLINK_1e.06 TRUE 297.2 Suicide or self-inflicted injury Both 0 7 5 mental disorders magenta 7, 0 2 2 1 2 PRS_PLINK_1e.06 TRUE 300 Anxiety disorders Both 25 19 5 mental disorders magenta 19, 25 5, 7 5, 4 4, 4 5, 9 -0.00378 0.396 0.992 0.003 0.996 0.462 2.14 -0.351 1.4 0.802 0.096 0.704 0.0341 7.77 0.0747 1.19 0.95 0.022 1.08 0.131 23.3 1.4 1.41 0.321 0.494 4.06 0.262 443 PRS_PLINK_1e.06 TRUE 300.1 Anxiety disorder Both 24 19 5 mental disorders magenta 19, 24 5, 7 5, 4 4, 4 5, 8 -0.0164 0.395 0.967 0.015 0.984 0.458 2.1 -0.351 1.4 0.802 0.096 0.704 0.0341 7.77 0.0747 1.19 0.95 0.022 1.08 0.131 23.3 1.26 1.39 0.365 0.438 3.53 0.239 413 PRS_PLINK_1e.06 TRUE 300.11 Generalized anxiety disorder Both 12 18 5 mental disorders magenta 18, 12 5, 5 4, 1 4, 2 5, 4 -0.244 0.541 0.652 0.186 0.784 0.243 2.03 -2.42 2.83 0.392 0.406 0.0886 0.000122 8.27 0.781 1.71 0.647 0.189 2.18 0.144 177 -0.591 1.4 0.673 0.172 0.554 0.0317 5.71 PRS_PLINK_1e.06 TRUE 300.12 Agorophobia, social phobia, and panic disorder Both 2 15 5 mental disorders magenta 15, 2 4, 0 4, 1 3, 0 4, 1 0.765 1.38 0.581 0.236 2.15 0.0353 1130 -0.444 4030 1 0 0.641 0.52 1.94 2 3.7 0.589 0.23 7.37 0.022 2390 PRS_PLINK_1e.06 TRUE 300.13 Phobia Both 3 12 5 mental disorders magenta 12, 3 3, 0 3, 1 3, 1 3, 1 0.0917 0.782 0.907 0.043 1.1 0.0448 5.96 -0.0255 424 1 0 0.975 0.0331 188 -0.403 2470 1 0 0.668 0.0239 2.15 -0.325 337 0.999 0 0.722 0.585 0.714 PRS_PLINK_1e.06 TRUE 300.3 Obsessive-compulsive disorders Both 0 6 5 mental disorders magenta 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 300.4 Dysthymic disorder Both 8 17 5 mental disorders magenta 17, 8 5, 1 4, 2 4, 1 4, 4 -0.396 1.24 0.749 0.125 0.673 0.025 11.6 0.29 3.57 0.935 0.029 1.34 1.19 1.4 -0.588 2.23 0.792 0.102 0.555 0.0199 44.6 1.38 2.57 0.59 0.229 3.99 0.0315 1950 PRS_PLINK_1e.06 TRUE 300.8 Acute reaction to stress Both 0 2 5 mental disorders magenta 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 300.9 Posttraumatic stress disorder Both 1 7 5 mental disorders magenta 7, 1 2, 1 2, 0 1, 0 2, 0 -0.558 903 1 0 0.573 0.326 0.899 0.392 5010 1 0 1.48 0.232 5.44 -0.0946 1830 1 0 0.91 0.292 4.17 0.488 4780 1 0 1.63 0.174 10.4 PRS_PLINK_1e.06 TRUE 301 Personality disorders Both 0 6 5 mental disorders magenta 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 301.2 Antisocial/borderline personality disorder Both 0 3 5 mental disorders magenta 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 302 Sexual and gender identity disorders Both 9 13 5 mental disorders magenta 13, 9 4, 6 3, 0 3, 0 3, 3 0.347 0.932 0.709 0.149 1.42 0.29 20.7 -2.75 4.99 0.581 0.235 0.0639 0.0475 87.9 0.0019 2.59 0.999 0 1 0.0091 375 1.53 2.08 0.462 0.336 4.61 0.111 18200 PRS_PLINK_1e.06 TRUE 302.1 Decreased libido Both 1 4 5 mental disorders magenta 4, 1 1, 1 1, 0 1, 0 1, 0 0.303 9560000 1 0 1.35 0.113 6.68 0.00248 28.8 1 0 1 0.967 1.03 0.0157 35.6 1 0 1.02 0.939 1.1 0.00893 52.4 1 0 1.01 0.952 1.08 PRS_PLINK_1e.06 TRUE 303 Psychogenic and somatoform disorders Both 8 16 5 mental disorders magenta 16, 8 4, 3 4, 2 4, 2 4, 1 0.752 1.17 0.52 0.284 2.12 0.31 355 -1.41 3.37 0.675 0.171 0.243 0.000777 42.4 0.328 2.87 0.909 0.041 1.39 0.0104 2880 2.38 2.72 0.381 0.419 10.8 0.288 5860 PRS_PLINK_1e.06 TRUE 303.1 Dissociative disorder Both 0 5 5 mental disorders magenta 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 303.3 Psychogenic disorder Both 8 16 5 mental disorders magenta 16, 8 4, 3 4, 2 4, 2 4, 1 0.752 1.17 0.52 0.284 2.12 0.31 355 -1.41 3.37 0.675 0.171 0.243 0.000777 42.4 0.328 2.87 0.909 0.041 1.39 0.0104 2880 2.38 2.72 0.381 0.419 10.8 0.288 5860 PRS_PLINK_1e.06 TRUE 303.31 Gastrointestinal malfunction arising from mental factors Both 1 5 5 mental disorders magenta 5, 1 2, 1 1, 0 1, 0 1, 0 -6.25 1.45e+08 1 0 0.00192 4.98e-18 1.29e+14 0.0873 4950 1 0 1.09 0.0792 1.23 -7.35 1.2e+09 1 0 0.00064 6.77e-49 2.52e+22 0.0519 3160 1 0 1.05 0.18 2.48 PRS_PLINK_1e.06 TRUE 303.4 Somatoform disorder Both 0 13 5 mental disorders magenta 13, 0 4 3 3 3 PRS_PLINK_1e.06 TRUE 304 Adjustment reaction Both 10 18 5 mental disorders magenta 18, 10 5, 5 4, 0 4, 1 5, 4 -0.397 0.636 0.532 0.274 0.672 0.207 1.98 -2.32 2.66 0.384 0.416 0.0984 0.0842 4.62 0.153 1.76 0.931 0.031 1.17 0.0616 142 -0.715 1.67 0.668 0.175 0.489 0.017 7.95 PRS_PLINK_1e.06 TRUE 305.2 Eating disorder Both 1 10 5 mental disorders magenta 10, 1 3, 0 2, 1 2, 0 3, 0 3.04 6 0.613 0.213 20.9 0.00277 581000 -0.177 4170 1 0 0.838 0.814 1.88 PRS_PLINK_1e.06 TRUE 306 Other mental disorder Both 6 14 5 mental disorders magenta 14, 6 4, 4 3, 1 3, 0 4, 1 -1.06 1.01 0.294 0.531 0.347 0.0085 12.7 -0.0357 4.77 0.994 0.003 0.965 0.813 1.04 -1.15 3.45 0.738 0.132 0.316 0.0066 10.3 -1.47 4.02 0.716 0.145 0.231 8.2e-09 1740 PRS_PLINK_1e.06 TRUE 306.1 Mental disorders durring/after pregnancy Female 1 6 5 mental disorders magenta 6, 1 2, 0 1, 0 1, 0 2, 1 -0.031 741 1 0 0.969 0.686 1.29 0.268 2460 1 0 1.31 0.681 5.38 PRS_PLINK_1e.06 TRUE 306.9 Tension headache Both 4 10 5 mental disorders magenta 10, 4 3, 3 2, 0 2, 0 3, 1 -0.482 1.4 0.73 0.137 0.618 0.029 23.7 -0.163 1210 1 0 0.85 0.454 1.32 -0.456 5560 1 0 0.634 0.0602 1.75 -0.657 10.5 0.95 0.022 0.518 0.496 0.542 PRS_PLINK_1e.06 TRUE 312 Conduct disorders Both 2 1 5 mental disorders magenta 1, 2 0.00784 924 1 0 1.01 0.651 1.02 PRS_PLINK_1e.06 TRUE 312.3 Impulse control disorder Both 1 0 5 mental disorders magenta 0, 1 PRS_PLINK_1e.06 TRUE 313 Pervasive developmental disorders Both 3 28 5 mental disorders magenta 28, 3 6, 1 7, 0 7, 0 7, 2 0.0939 0.631 0.882 0.055 1.1 0.267 5.74 -0.374 1.86 0.841 0.075 0.688 0.0205 133 -0.969 1.62 0.549 0.26 0.38 0.0219 3.86 0.356 1.96 0.856 0.068 1.43 0.045 487 PRS_PLINK_1e.06 TRUE 313.1 Attention deficit hyperactivity disorder Both 3 25 5 mental disorders magenta 25, 3 6, 1 6, 0 6, 0 6, 2 0.111 0.697 0.874 0.059 1.12 0.26 10.2 -0.306 1.97 0.877 0.057 0.736 0.000892 328 -0.409 2.09 0.845 0.073 0.664 0.01 139 0.316 2.03 0.876 0.057 1.37 0.0053 626 PRS_PLINK_1e.06 TRUE 313.2 Tics and stuttering Both 0 1 5 mental disorders magenta 1, 0 PRS_PLINK_1e.06 TRUE 313.3 Autism Both 0 2 5 mental disorders magenta 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 315 Develomental delays and disorders Both 2 13 5 mental disorders magenta 13, 2 4, 1 3, 0 3, 0 3, 1 0.293 1.19 0.805 0.094 1.34 0.203 15.4 0.0761 11300000 1 0 1.08 0.0154 2.46 0.28 658 1 0 1.32 0.742 1.54 0.741 108 0.995 0.002 2.1 1.97 2.05 PRS_PLINK_1e.06 TRUE 315.1 Learning disorder Both 0 2 5 mental disorders magenta 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 315.2 Speech and language disorder Both 2 5 5 mental disorders magenta 5, 2 2, 0 1, 1 1, 0 1, 1 -0.0405 450 1 0 0.96 0.348 3.18 -0.0867 599 1 0 0.917 0.91 1.08 0.302 27900 1 0 1.35 0.359 2.99 PRS_PLINK_1e.06 TRUE 316 Substance addiction and disorders Both 3 49 5 mental disorders magenta 49, 3 12, 2 12, 1 12, 0 12, 0 -0.678 0.57 0.234 0.631 0.508 0.00404 1.99 -0.252 1.5 0.866 0.062 0.777 0.022 20.5 -0.0291 1.47 0.984 0.007 0.971 0.00795 1120 -0.281 1.32 0.832 0.08 0.755 0.00458 105 PRS_PLINK_1e.06 TRUE 316.1 Polyneuropathy due to drugs Both 0 4 5 mental disorders magenta 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 317 Alcohol-related disorders Both 0 36 5 mental disorders magenta 36, 0 8 9 9 9 PRS_PLINK_1e.06 TRUE 317.1 Alcoholism Both 0 29 5 mental disorders magenta 29, 0 7 7 7 7 PRS_PLINK_1e.06 TRUE 317.11 Alcoholic liver damage Both 0 7 5 mental disorders magenta 7, 0 2 2 1 2 PRS_PLINK_1e.06 TRUE 318 Tobacco use disorder Both 9 51 5 mental disorders magenta 51, 9 12, 0 13, 4 12, 3 13, 2 0.232 0.391 0.554 0.257 1.26 0.614 2.82 1.97 1.77 0.267 0.573 7.16 0.198 34600 0.201 1.49 0.893 0.049 1.22 0.0382 134 0.163 1.35 0.904 0.044 1.18 0.00908 151 PRS_PLINK_1e.06 TRUE 320 Meningitis Both 1 3 6 neurological darkblue 3, 1 1, 1 1, 0 1, 0 1, 1 0.227 11500 1 0 1.26 0.177 1.42 -0.00573 2350 1 0 0.994 0.959 1.22 0.00937 52.9 1 0 1.01 0.942 1.07 PRS_PLINK_1e.06 TRUE 323 Encephalitis Both 1 1 6 neurological darkblue 1, 1 0.102 70.3 0.999 0.001 1.11 0.817 1.2 PRS_PLINK_1e.06 TRUE 323.8 Encephalitis, non-infectious Both 1 1 6 neurological darkblue 1, 1 0.102 70.3 0.999 0.001 1.11 0.817 1.2 PRS_PLINK_1e.06 TRUE 324 Other CNS infection and poliomyelitis Both 0 5 6 neurological darkblue 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 327 Sleep disorders Both 24 38 6 neurological darkblue 38, 24 10, 4 9, 11 9, 6 10, 3 -0.124 0.308 0.687 0.163 0.883 0.499 1.57 0.558 1.08 0.606 0.218 1.75 0.227 13.9 0.411 0.942 0.662 0.179 1.51 0.278 8.52 -0.00344 1.2 0.998 0.001 0.997 0.103 12.1 PRS_PLINK_1e.06 TRUE 327.1 Hypersomnia Both 5 21 6 neurological darkblue 21, 5 6, 0 5, 3 5, 2 5, 0 0.377 0.91 0.679 0.168 1.46 0.275 787 1.8 2.46 0.463 0.335 6.06 0.0932 1380 -0.352 2.73 0.897 0.047 0.703 0.000108 2280 PRS_PLINK_1e.06 TRUE 327.3 Sleep apnea Both 21 37 6 neurological darkblue 37, 21 10, 4 9, 8 9, 5 9, 3 -0.158 0.303 0.602 0.22 0.854 0.488 1.5 0.0526 1.17 0.964 0.016 1.05 0.0757 9.54 0.234 0.931 0.801 0.096 1.26 0.23 7.05 0.153 1.29 0.905 0.043 1.17 0.101 16.6 PRS_PLINK_1e.06 TRUE 327.31 Central/nonobstroctive sleep apnea Both 2 5 6 neurological darkblue 5, 2 2, 2 1, 0 1, 0 1, 0 0.207 6110 1 0 1.23 0.684 1.28 -0.202 3950 1 0 0.817 0.0345 3.06 -0.158 3740 1 0 0.854 0.069 2.41 -0.263 6110 1 0 0.768 0.000552 53.3 PRS_PLINK_1e.06 TRUE 327.32 Obstructive sleep apnea Both 18 35 6 neurological darkblue 35, 18 9, 5 9, 7 8, 4 9, 2 -0.138 0.348 0.693 0.159 0.871 0.46 1.66 0.125 1.1 0.91 0.041 1.13 0.0976 8.58 0.326 0.918 0.723 0.141 1.39 0.296 7.88 -0.422 1.51 0.78 0.108 0.656 0.0159 15.8 PRS_PLINK_1e.06 TRUE 327.4 Insomnia Both 10 35 6 neurological darkblue 35, 10 9, 1 9, 6 8, 3 9, 0 0.207 0.571 0.717 0.144 1.23 0.404 4.94 0.747 1.41 0.597 0.224 2.11 0.103 3030 0.629 1.36 0.643 0.192 1.87 0.074 92.3 0.13 1.55 0.933 0.03 1.14 0.017 117 PRS_PLINK_1e.06 TRUE 327.41 Organic or persistent insomnia Both 3 11 6 neurological darkblue 11, 3 3, 0 3, 2 2, 1 3, 0 0.226 1.25 0.857 0.067 1.25 0.175 49 -0.24 4650 1 0 0.786 0.131 1.77 -0.000838 1200 1 0 0.999 0.913 1.39 PRS_PLINK_1e.06 TRUE 327.5 Parasomnia Both 3 9 6 neurological darkblue 9, 3 3, 2 2, 0 2, 0 2, 1 -1.27 5.77 0.825 0.083 0.279 0.256 0.308 -0.417 1230 1 0 0.659 1.8e-06 1600000 0.0714 2020 1 0 1.07 0.458 2.87 1.12 2620 1 0 3.07 4.67 64.5 PRS_PLINK_1e.06 TRUE 327.6 Circadian rhythm sleep disorder Both 0 6 6 neurological darkblue 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 327.7 Sleep related movement disorders Both 3 21 6 neurological darkblue 21, 3 6, 0 5, 0 5, 2 5, 1 0.0177 0.618 0.977 0.01 1.02 0.339 3.71 1.48 1.58 0.351 0.455 4.37 0.496 87.8 0.121 2.75 0.965 0.016 1.13 0.0108 70.5 PRS_PLINK_1e.06 TRUE 327.71 Restless legs syndrome Both 2 17 6 neurological darkblue 17, 2 5, 0 4, 0 4, 1 4, 1 0.164 0.926 0.859 0.066 1.18 0.156 19.1 0.589 2.89 0.839 0.076 1.8 0.0224 133 0.29 4040 1 0 1.34 0.111 16.1 PRS_PLINK_1e.06 TRUE 327.72 Sleep related leg cramps Both 0 1 6 neurological darkblue 1, 0 PRS_PLINK_1e.06 TRUE 331 Other cerebral degenerations Both 2 7 6 neurological darkblue 7, 2 2, 0 2, 0 1, 0 2, 2 -1.74 101 0.986 0.006 0.176 0.181 0.775 -0.0615 7360 1 0 0.94 0.094 9.49 PRS_PLINK_1e.06 TRUE 331.1 Hydrocephalus Both 0 1 6 neurological darkblue 1, 0 PRS_PLINK_1e.06 TRUE 331.9 Cerebral degeneration, unspecified Both 2 3 6 neurological darkblue 3, 2 1, 0 1, 0 1, 2 1, 0 -0.719 2030 1 0 0.487 0.0316 6.36 1.24e-05 10500 1 0 1 0.0793 11.9 PRS_PLINK_1e.06 TRUE 332 Parkinson's disease Both 0 1 6 neurological darkblue 1, 0 PRS_PLINK_1e.06 TRUE 333 Extrapyramidal disease and abnormal movement disorders Both 6 27 6 neurological darkblue 27, 6 6, 0 7, 1 6, 1 7, 4 0.955 0.661 0.149 0.828 2.6 0.847 24.4 0.177 2.43 0.942 0.026 1.19 0.0192 261000 0.291 2.38 0.902 0.045 1.34 0.000581 50.8 2.38 2.01 0.237 0.624 10.8 0.506 648 PRS_PLINK_1e.06 TRUE 333.1 Essential tremor Both 1 6 6 neurological darkblue 6, 1 2, 0 1, 0 1, 0 2, 1 0.0635 219 1 0 1.07 1.17 1.58 0.00291 94.9 1 0 1 0.713 1.39 PRS_PLINK_1e.06 TRUE 333.2 Myoclonus Both 0 2 6 neurological darkblue 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 333.4 Torsion dystonia Both 0 4 6 neurological darkblue 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 333.8 Other degenerative diseases of the basal ganglia Both 1 1 6 neurological darkblue 1, 1 -0.00173 39 1 0 0.998 0.974 8.96 PRS_PLINK_1e.06 TRUE 334 Degenerative disease of the spinal cord Both 0 11 6 neurological darkblue 11, 0 3 3 2 3 PRS_PLINK_1e.06 TRUE 335 Multiple sclerosis Both 1 3 6 neurological darkblue 3, 1 1, 0 1, 0 1, 1 1, 0 -6.42 110000 1 0 0.00162 3.69e-18 4230000 -0.00388 53.8 1 0 0.996 0.952 1.05 PRS_PLINK_1e.06 TRUE 337 Disorders of the autonomic nervous system Both 8 14 6 neurological darkblue 14, 8 3, 3 3, 2 3, 2 4, 1 -0.232 0.753 0.758 0.12 0.793 0.197 3 -0.823 3.1 0.79 0.102 0.439 0.408 0.5 0.288 7.54 0.97 0.013 1.33 8.73e-09 960000 -0.331 2.66 0.901 0.045 0.718 0.00384 93.2 PRS_PLINK_1e.06 TRUE 337.1 Peripheral autonomic neuropathy Both 6 11 6 neurological darkblue 11, 6 3, 3 3, 1 2, 2 3, 0 -0.997 1.21 0.408 0.389 0.369 0.291 2.68 -2.95 28.9 0.919 0.037 0.0522 0.0434 0.0617 5.27 57.2 0.927 0.033 195 138 273 0.909 11.7 0.938 0.028 2.48 2.29 2.66 PRS_PLINK_1e.06 TRUE 338 Pain Both 36 27 6 neurological darkblue 27, 36 7, 11 7, 14 6, 7 7, 3 -0.305 0.292 0.296 0.529 0.737 0.417 1.24 0.536 0.824 0.515 0.288 1.71 0.413 8.05 -0.261 0.79 0.741 0.13 0.77 0.19 3.03 -1.75 1.21 0.147 0.833 0.174 0.0141 1.23 PRS_PLINK_1e.06 TRUE 338.1 Acute pain Both 23 27 6 neurological darkblue 27, 23 7, 6 7, 8 6, 5 7, 3 -0.228 0.316 0.47 0.328 0.796 0.435 1.39 0.433 1.09 0.692 0.16 1.54 0.246 11.5 0.129 0.993 0.897 0.047 1.14 0.2 8.96 -1.57 1.3 0.225 0.647 0.207 0.00862 1.59 PRS_PLINK_1e.06 TRUE 338.2 Chronic pain Both 21 27 6 neurological darkblue 27, 21 7, 6 7, 10 6, 3 7, 2 -0.217 0.356 0.542 0.266 0.805 0.416 1.51 1.36 1.11 0.224 0.65 3.88 0.643 45.9 -0.481 1.03 0.64 0.194 0.618 0.0942 3.35 -1.28 1.64 0.436 0.361 0.278 0.00326 4.06 PRS_PLINK_1e.06 TRUE 339 Other headache syndromes Both 23 36 6 neurological darkblue 36, 23 9, 2 9, 9 9, 7 9, 4 -0.122 0.309 0.692 0.16 0.885 0.489 1.57 0.724 1.28 0.571 0.243 2.06 0.235 145 0.986 1.33 0.459 0.338 2.68 0.232 91.5 0.574 1.4 0.682 0.166 1.78 0.0819 443 PRS_PLINK_1e.06 TRUE 340 Migraine Both 19 35 6 neurological darkblue 35, 19 9, 2 9, 9 8, 6 9, 1 -0.233 0.33 0.48 0.319 0.792 0.419 1.45 0.289 1.12 0.796 0.099 1.34 0.199 10.1 1.26 1.11 0.256 0.591 3.54 0.594 69.1 0.107 1.43 0.94 0.027 1.11 0.0167 551 PRS_PLINK_1e.06 TRUE 340.1 Migrain with aura Both 8 25 6 neurological darkblue 25, 8 7, 5 6, 1 6, 2 6, 0 -0.484 0.586 0.409 0.389 0.616 0.2 1.75 -0.247 1.88 0.896 0.048 0.781 0.0287 19.2 0.216 1.71 0.899 0.046 1.24 0.0613 59 -1.21 1.58 0.445 0.352 0.298 0.00157 3.8 PRS_PLINK_1e.06 TRUE 342 Hemiplegia Both 0 5 6 neurological darkblue 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 343 Infantile cerebral palsy Both 0 1 6 neurological darkblue 1, 0 PRS_PLINK_1e.06 TRUE 344 Other paralytic syndromes Both 1 6 6 neurological darkblue 6, 1 2, 0 1, 0 1, 0 2, 1 -0.0468 361 1 0 0.954 0.508 1.71 -0.0129 35.6 1 0 0.987 0.899 1.17 PRS_PLINK_1e.06 TRUE 345 Epilepsy, recurrent seizures, convulsions Both 5 34 6 neurological darkblue 34, 5 8, 0 8, 0 8, 0 9, 5 0.816 0.64 0.202 0.694 2.26 0.759 38.1 1.3 1.52 0.392 0.407 3.66 0.186 542 PRS_PLINK_1e.06 TRUE 345.1 Epilepsy Both 1 13 6 neurological darkblue 13, 1 4, 0 3, 0 3, 0 3, 1 1.01 1.9 0.595 0.226 2.75 0.174 166 0.586 154 0.997 0.001 1.8 10.1 17.6 PRS_PLINK_1e.06 TRUE 345.11 Generalized convulsive epilepsy Both 1 3 6 neurological darkblue 3, 1 1, 0 1, 1 1, 0 1, 0 -0.244 1620 1 0 0.784 0.179 1.51 -0.696 12100 1 0 0.499 0.195 4.75 PRS_PLINK_1e.06 TRUE 345.12 Partial epilepsy Both 1 6 6 neurological darkblue 6, 1 2, 0 1, 0 1, 0 2, 1 0.0216 864 1 0 1.02 0.0349 26.2 13.1 5540 0.998 0.001 499000 2.39e-08 2.29e+21 PRS_PLINK_1e.06 TRUE 345.3 Convulsions Both 5 32 6 neurological darkblue 32, 5 7, 0 8, 0 8, 0 8, 5 0.962 0.734 0.19 0.721 2.62 0.773 9310000 1.19 1.48 0.419 0.378 3.3 0.172 427 PRS_PLINK_1e.06 TRUE 346 Abnormal findings on study of brain and/or nervous system Both 0 5 6 neurological darkblue 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 346.1 Nonspecific abnormal findings on radiological and other examination of skull and head Both 3 12 6 neurological darkblue 12, 3 3, 0 3, 0 3, 2 3, 1 0.662 0.963 0.491 0.309 1.94 0.515 165 -0.0896 324 1 0 0.914 0.452 1.34 -0.000673 320 1 0 0.999 0.507 1.91 PRS_PLINK_1e.06 TRUE 346.2 Nonspecific abnormal results of function study of brain and central nervous system Both 0 2 6 neurological darkblue 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 347 Cataplexy and narcolepsy Both 0 1 6 neurological darkblue 1, 0 PRS_PLINK_1e.06 TRUE 348 Other conditions of brain Both 2 17 6 neurological darkblue 17, 2 5, 0 4, 1 4, 0 4, 1 -0.399 0.904 0.659 0.181 0.671 0.0281 306 -2.61 448 0.995 0.002 0.0738 4.68e-17 2.11e+10 0.482 11.1 0.965 0.015 1.62 0.192 1.83 PRS_PLINK_1e.06 TRUE 348.2 Cerebral edema and compression of brain Both 1 10 6 neurological darkblue 10, 1 3, 0 2, 1 2, 0 3, 0 -0.0905 2.07 0.965 0.015 0.913 0.039 22.9 -1.69 3280 1 0 0.185 5.74e-06 196 PRS_PLINK_1e.06 TRUE 348.4 Cerebral cysts Both 0 4 6 neurological darkblue 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 348.7 Coma Both 0 2 6 neurological darkblue 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 348.8 Encephalopathy, not elsewhere classified Both 0 6 6 neurological darkblue 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 348.9 Other conditions of brain, NOS Both 3 20 6 neurological darkblue 20, 3 5, 2 5, 0 5, 1 5, 0 -1.04 0.875 0.236 0.626 0.355 0.000747 1.42 -6.66 9.18 0.468 0.329 0.00128 1.06e-09 607 -0.65 4.65 0.889 0.051 0.522 0.000147 2150 -1.67 2.29 0.466 0.331 0.188 0.00102 6.5 PRS_PLINK_1e.06 TRUE 349 Other and unspecified disorders of the nervous system Both 1 10 6 neurological darkblue 10, 1 3, 0 2, 0 2, 0 3, 1 -0.303 1.61 0.851 0.07 0.739 0.057 8.71 0.022 1780 1 0 1.02 0.306 4.11 PRS_PLINK_1e.06 TRUE 350 Abnormal movement Both 12 46 6 neurological darkblue 46, 12 11, 4 11, 4 11, 2 12, 2 -0.267 0.389 0.493 0.307 0.766 0.353 1.65 0.445 1.14 0.695 0.158 1.56 0.21 13.7 -0.761 1.19 0.524 0.281 0.467 0.0292 5.44 -0.183 0.974 0.851 0.07 0.833 0.122 5.67 PRS_PLINK_1e.06 TRUE 350.1 Abnormal involuntary movements Both 5 33 6 neurological darkblue 33, 5 8, 3 8, 1 8, 0 8, 1 -0.434 0.476 0.362 0.441 0.648 0.165 1.57 -1.03 1.78 0.565 0.248 0.359 0.00173 6.46 -1.3 1.6 0.417 0.38 0.272 0.000647 4.21 -0.456 1.35 0.735 0.134 0.634 0.00434 6.72 PRS_PLINK_1e.06 TRUE 350.2 Abnormality of gait Both 8 28 6 neurological darkblue 28, 8 7, 1 7, 2 7, 3 7, 2 0.771 0.83 0.353 0.453 2.16 0.508 185 -0.617 2.87 0.83 0.081 0.54 0.00274 184 -0.262 1.96 0.894 0.049 0.77 0.0234 393 2.18 2.32 0.348 0.459 8.85 0.076 4760000 PRS_PLINK_1e.06 TRUE 350.3 Lack of coordination Both 3 12 6 neurological darkblue 12, 3 3, 1 3, 0 3, 1 3, 1 -0.0508 2.5 0.984 0.007 0.95 0.0044 246 -0.588 3430 1 0 0.555 0.00427 45.6 -0.0284 396 1 0 0.972 0.293 34.3 0.0941 1920 1 0 1.1 0.409 3.48 PRS_PLINK_1e.06 TRUE 350.5 Abnormal reflex Both 0 3 6 neurological darkblue 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 350.6 Disturbances of sensation of smell and taste Both 0 9 6 neurological darkblue 9, 0 3 2 2 2 PRS_PLINK_1e.06 TRUE 351 Other peripheral nerve disorders Both 18 39 6 neurological darkblue 39, 18 10, 5 10, 6 9, 3 10, 3 -0.557 0.35 0.112 0.952 0.573 0.286 1.08 0.954 1.04 0.361 0.442 2.6 0.419 24 -3.25 2.16 0.133 0.877 0.0387 5.75e-06 1.6 0.419 1.09 0.701 0.154 1.52 0.225 13.4 PRS_PLINK_1e.06 TRUE 352 Disorders of other cranial nerves Both 2 13 6 neurological darkblue 13, 2 4, 1 3, 0 3, 1 3, 0 0.404 2.06 0.845 0.073 1.5 0.0457 64.6 -0.474 4050 1 0 0.623 0.0119 2.98 2.1 113 0.985 0.007 8.2 2640 3070 -0.321 1150 1 0 0.726 0.622 1.75 PRS_PLINK_1e.06 TRUE 352.1 Trigeminal nerve disorders [CN5] Both 1 7 6 neurological darkblue 7, 1 2, 0 2, 0 1, 1 2, 0 -0.0116 341 1 0 0.988 0.551 2.09 0.193 17500 1 0 1.21 0.307 2.13 PRS_PLINK_1e.06 TRUE 352.2 Facial nerve disorders [CN7] Both 1 5 6 neurological darkblue 5, 1 2, 1 1, 0 1, 0 1, 0 -0.0527 812 1 0 0.949 0.636 1.14 0.0546 550 1 0 1.06 0.589 1.64 10.8 20400 1 0 48900 0.000634 1.98e+12 -1.59 3180 1 0 0.204 0.000236 106 PRS_PLINK_1e.06 TRUE 353 Nerve root and plexus disorders Both 3 33 6 neurological darkblue 33, 3 9, 1 8, 1 8, 1 8, 0 -0.19 0.596 0.75 0.125 0.827 0.181 3.52 -0.17 1.84 0.926 0.033 0.843 0.000401 24.7 -0.0691 1.35 0.959 0.018 0.933 0.0286 24.3 -0.0512 2.01 0.98 0.009 0.95 0.00386 69.6 PRS_PLINK_1e.06 TRUE 353.1 Nerve plexus lesions Both 0 2 6 neurological darkblue 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 355 Complex regional/central pain syndrome Both 0 6 6 neurological darkblue 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 355.1 Chronic pain syndrome Both 0 11 6 neurological darkblue 11, 0 3 3 2 3 PRS_PLINK_1e.06 TRUE 356 Hereditary and idiopathic peripheral neuropathy Both 13 19 6 neurological darkblue 19, 13 5, 1 5, 5 4, 3 5, 3 -0.259 0.45 0.565 0.248 0.772 0.332 1.67 0.102 2.53 0.968 0.014 1.11 5.56e-07 66.7 1.49 3.08 0.629 0.201 4.42 0.0454 10600 0.25 1.85 0.892 0.049 1.28 0.0483 38.9 PRS_PLINK_1e.06 TRUE 357 Inflammatory and toxic neuropathy Both 14 23 6 neurological darkblue 23, 14 6, 2 6, 5 5, 3 6, 3 -0.859 0.641 0.18 0.744 0.424 0.0997 1.4 0.326 2.76 0.906 0.043 1.39 2.83e-09 366 1.06 2.48 0.668 0.176 2.9 0.000704 857 -0.349 3.14 0.911 0.04 0.705 0.00156 115 PRS_PLINK_1e.06 TRUE 358 Myoneural disorders Both 3 5 6 neurological darkblue 5, 3 2, 0 1, 1 1, 0 1, 1 -0.366 112 0.997 0.001 0.693 0.357 1.58 11.6 1.43e+09 1 0 105000 1.61e-09 4.77e+19 -0.0291 6800 1 0 0.971 0.887 2.51 PRS_PLINK_1e.06 TRUE 359 Muscular dystrophies and other myopathies Both 5 12 6 neurological darkblue 12, 5 3, 0 3, 1 3, 0 3, 4 0.0973 0.921 0.916 0.038 1.1 0.229 7.07 8.76 5630 0.999 0.001 6400 3.57e-32 4.85e+30 0.037 3.56 0.992 0.004 1.04 0.00242 152 PRS_PLINK_1e.06 TRUE 359.2 Myopathy Both 5 10 6 neurological darkblue 10, 5 3, 0 2, 1 2, 0 3, 4 0.167 0.937 0.858 0.066 1.18 0.267 16.3 -13.2 4370 0.998 0.001 1.86e-06 1.03e-34 1.91e+22 -6.15 10.6 0.562 0.251 0.00212 3.78e-11 11200 PRS_PLINK_1e.06 TRUE 360.2 Progressive myopia Both 0 1 7 sense organs darkseagreen4 1, 0 PRS_PLINK_1e.06 TRUE 361 Retinal detachments and defects Both 0 10 7 sense organs darkseagreen4 10, 0 3 2 2 3 PRS_PLINK_1e.06 TRUE 361.1 Retinal detachment with retinal defect Both 0 6 7 sense organs darkseagreen4 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 362 Other retinal disorders Both 11 16 7 sense organs darkseagreen4 16, 11 4, 3 4, 4 4, 1 4, 3 -0.0789 0.604 0.896 0.048 0.924 0.299 2.77 -0.658 1.93 0.733 0.135 0.518 0.0217 10.1 1.38 17.2 0.936 0.029 3.98 3.5 4.47 3.11 4.63 0.502 0.299 22.3 0.0123 7180000 PRS_PLINK_1e.06 TRUE 362.2 Degeneration of macula and posterior pole of retina Both 3 10 7 sense organs darkseagreen4 10, 3 3, 0 2, 2 2, 0 3, 1 0.364 2.3 0.874 0.058 1.44 0.00645 80.7 1.04 620 0.999 0.001 2.84 1.99 2450 0.0978 487 1 0 1.1 0.281 6.44 PRS_PLINK_1e.06 TRUE 362.21 Macular degeneration, dry Both 0 2 7 sense organs darkseagreen4 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 362.22 Macular degeneration, wet Both 0 1 7 sense organs darkseagreen4 1, 0 PRS_PLINK_1e.06 TRUE 362.23 Cystoid macular degeneration of retina Both 0 4 7 sense organs darkseagreen4 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 362.26 Macular puckering of retina Both 2 7 7 sense organs darkseagreen4 7, 2 2, 0 2, 1 1, 1 2, 0 0.594 174 0.997 0.001 1.81 0.243 1.48 -4.93 824 0.995 0.002 0.00722 1.31e-12 206000 -0.0102 39 1 0 0.99 0.572 1.15 PRS_PLINK_1e.06 TRUE 362.27 Drusen (degenerative) of retina Both 1 3 7 sense organs darkseagreen4 3, 1 1, 0 1, 1 1, 0 1, 0 -0.25 1040 1 0 0.778 0.371 1.28 -0.172 4520 1 0 0.842 0.837 1.47 PRS_PLINK_1e.06 TRUE 362.29 Macular degeneration (senile) of retina NOS Both 3 10 7 sense organs darkseagreen4 10, 3 3, 0 2, 2 2, 0 3, 1 0.364 2.3 0.874 0.058 1.44 0.00645 80.7 1.04 620 0.999 0.001 2.84 1.99 2450 0.0978 487 1 0 1.1 0.281 6.44 PRS_PLINK_1e.06 TRUE 362.3 Other nondiabetic retinopathy Both 3 9 7 sense organs darkseagreen4 9, 3 3, 2 2, 0 2, 0 2, 1 -0.137 1.34 0.919 0.037 0.872 0.109 6.8 -0.0956 678 1 0 0.909 0.332 1.34 -0.407 2640 1 0 0.666 0.0302 1.38 -0.367 713 1 0 0.693 0.112 0.299 PRS_PLINK_1e.06 TRUE 362.31 Separation of retinal layers Both 0 4 7 sense organs darkseagreen4 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 362.4 Retinal vascular changes and abnomalities Both 4 3 7 sense organs darkseagreen4 3, 4 1, 2 1, 0 1, 2 1, 2 -0.101 1490 1 0 0.904 0.778 1.24 -0.0375 2950 1 0 0.963 0.5 1.55 0.0775 6070 1 0 1.08 0.285 1.16 PRS_PLINK_1e.06 TRUE 362.6 Peripheral retinal degenerations Both 2 4 7 sense organs darkseagreen4 4, 2 1, 0 1, 0 1, 0 1, 2 0.0166 51.9 1 0 1.02 0.284 2.46 0.0101 310 1 0 1.01 0.904 1.31 PRS_PLINK_1e.06 TRUE 362.7 Hereditary retinal dystrophies Both 1 0 7 sense organs darkseagreen4 0, 1 PRS_PLINK_1e.06 TRUE 362.8 Retinal hemorrhage/ischemia Both 0 2 7 sense organs darkseagreen4 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 362.9 Retinal edema Both 1 4 7 sense organs darkseagreen4 4, 1 1, 1 1, 0 1, 0 1, 0 0.0732 1590 1 0 1.08 0.777 1.61 -0.00229 45.3 1 0 0.998 0.962 1.05 0.0149 43.6 1 0 1.01 0.92 1.1 -1.91 98800 1 0 0.148 3.92e-05 1720 PRS_PLINK_1e.06 TRUE 363 Chorioretinal inflammations, scars, and other disorders of choroid Both 0 7 7 sense organs darkseagreen4 7, 0 2 2 1 2 PRS_PLINK_1e.06 TRUE 363.3 Chorioretinal scars Both 0 5 7 sense organs darkseagreen4 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 364 Corneal opacity and other disorders of cornea Both 4 15 7 sense organs darkseagreen4 15, 4 4, 0 4, 0 3, 2 4, 2 0.858 1.22 0.481 0.317 2.36 0.283 115000 0.646 8.52 0.94 0.027 1.91 1.37 2.88 -3.1 20.7 0.881 0.055 0.0449 2.49e-11 2.64e+08 PRS_PLINK_1e.06 TRUE 364.1 Corneal opacity Both 2 8 7 sense organs darkseagreen4 8, 2 2, 0 2, 0 2, 1 2, 1 0.312 1.49 0.834 0.079 1.37 0.157 14.8 0.00036 1180 1 0 1 0.77 1.3 -2.24 257 0.993 0.003 0.106 0.000543 9.98 PRS_PLINK_1e.06 TRUE 364.2 Corneal edema Both 1 2 7 sense organs darkseagreen4 2, 1 1, 0 1, 1 1, 0 1, 1 -0.526 21400 1 0 0.591 0.00765 26.4 0.108 1830 1 0 1.11 0.0138 32.6 PRS_PLINK_1e.06 TRUE 364.4 Corneal degenerations Both 3 5 7 sense organs darkseagreen4 5, 3 2, 0 1, 0 1, 0 1, 3 0.456 88.7 0.996 0.002 1.58 8.02e-05 1.86 -0.182 705 1 0 0.833 0.126 1.31 PRS_PLINK_1e.06 TRUE 364.5 Corneal dystrophy Both 1 4 7 sense organs darkseagreen4 4, 1 1, 0 1, 0 1, 0 1, 1 -0.286 19600 1 0 0.751 0.234 2.93 -0.0321 1130 1 0 0.968 1.05 18.1 PRS_PLINK_1e.06 TRUE 365 Glaucoma Both 10 23 7 sense organs darkseagreen4 23, 10 6, 2 6, 2 5, 2 6, 4 0.512 0.531 0.335 0.475 1.67 0.669 5.32 0.243 3.7 0.948 0.023 1.28 2.63e-06 26100 -1.47 2.63 0.575 0.24 0.23 5.3e-05 19.1 2.43 1.98 0.22 0.658 11.3 0.554 831 PRS_PLINK_1e.06 TRUE 365.1 Open-angle glaucoma Both 3 6 7 sense organs darkseagreen4 6, 3 2, 0 1, 1 1, 0 2, 2 1.22 9.08 0.893 0.049 3.4 3.56 7.09 -0.0546 51.3 0.999 0 0.947 0.857 1.27 0.0163 474 1 0 1.02 0.811 1.58 PRS_PLINK_1e.06 TRUE 365.11 Primary open angle glaucoma Both 1 3 7 sense organs darkseagreen4 3, 1 1, 0 1, 0 1, 1 1, 0 -0.0093 1190 1 0 0.991 0.872 1.07 0.018 2670 1 0 1.02 0.94 1.04 PRS_PLINK_1e.06 TRUE 365.2 Primary angle-closure glaucoma Both 0 2 7 sense organs darkseagreen4 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 366 Cataract Both 22 22 7 sense organs darkseagreen4 22, 22 6, 4 5, 12 5, 1 6, 5 -0.418 0.506 0.409 0.389 0.658 0.195 1.6 1.46 1.51 0.334 0.477 4.32 0.382 199 -0.0321 2.02 0.987 0.006 0.968 0.000718 652 0.982 1.41 0.487 0.313 2.67 0.178 96.1 PRS_PLINK_1e.06 TRUE 366.1 Nonsenile Cataract Both 2 0 7 sense organs darkseagreen4 0, 2 PRS_PLINK_1e.06 TRUE 366.2 Senile cataract Both 19 18 7 sense organs darkseagreen4 18, 19 5, 2 4, 11 4, 1 5, 5 -0.322 0.565 0.568 0.246 0.724 0.212 1.94 3.97 2.66 0.136 0.867 53.1 0.394 4590000 -2.25 3.57 0.528 0.277 0.106 0.000105 16.1 0.885 1.47 0.546 0.262 2.42 0.0552 119 PRS_PLINK_1e.06 TRUE 367 Disorders of refraction and accommodation; blindness and low vision Both 25 39 7 sense organs darkseagreen4 39, 25 9, 8 10, 8 9, 2 10, 7 -0.00348 0.316 0.991 0.004 0.997 0.552 1.83 0.165 0.865 0.849 0.071 1.18 0.269 5.83 -2.61 1.8 0.147 0.832 0.0737 7.28e-05 1.27 0.235 1.17 0.84 0.075 1.27 0.105 16.4 PRS_PLINK_1e.06 TRUE 367.1 Myopia Both 22 36 7 sense organs darkseagreen4 36, 22 8, 8 9, 4 9, 3 9, 7 0.242 0.359 0.499 0.302 1.27 0.667 2.66 -0.51 0.907 0.574 0.241 0.6 0.119 2.84 -1.01 1.02 0.323 0.491 0.366 0.0467 2.08 -0.00299 1.12 0.998 0.001 0.997 0.0677 9.27 PRS_PLINK_1e.06 TRUE 367.2 Astigmatism Both 12 32 7 sense organs darkseagreen4 32, 12 7, 6 8, 2 8, 1 8, 3 -0.0542 0.404 0.893 0.049 0.947 0.455 2.13 -0.799 1.19 0.503 0.298 0.45 0.0472 3.26 -2.18 1.52 0.152 0.817 0.113 0.00112 1.18 0.325 1.12 0.772 0.112 1.38 0.191 12.5 PRS_PLINK_1e.06 TRUE 367.8 Hypermetropia Both 0 17 7 sense organs darkseagreen4 17, 0 5 4 4 4 PRS_PLINK_1e.06 TRUE 367.9 Blindness and low vision Both 3 14 7 sense organs darkseagreen4 14, 3 3, 1 3, 1 3, 0 4, 1 -1.87 1.76 0.289 0.54 0.154 0.132 2.9 -0.445 1610 1 0 0.641 0.12 0.0527 -0.0359 350 1 0 0.965 0.189 1.47 0.116 8.4 0.989 0.005 1.12 1.13 51.6 PRS_PLINK_1e.06 TRUE 368 Visual disturbances Both 15 46 7 sense organs darkseagreen4 46, 15 11, 1 11, 6 11, 5 12, 3 0.00813 0.354 0.982 0.008 1.01 0.518 2.05 0.81 1.29 0.53 0.276 2.25 0.237 35.4 1.75 1.45 0.228 0.641 5.74 0.548 2010 1.2 1.59 0.452 0.345 3.31 0.229 28500 PRS_PLINK_1e.06 TRUE 368.1 Amblyopia Both 2 11 7 sense organs darkseagreen4 11, 2 3, 1 3, 1 2, 0 3, 0 -0.256 2.59 0.921 0.036 0.774 0.00146 758 0.302 188 0.999 0.001 1.35 0.46 153 0.397 13600000 1 0 1.49 0.0313 3990 0.108 6750 1 0 1.11 0.385 1.19 PRS_PLINK_1e.06 TRUE 368.2 Diplopia and disorders of binocular vision Both 7 13 7 sense organs darkseagreen4 13, 7 4, 4 3, 1 3, 1 3, 1 -0.277 0.968 0.774 0.111 0.758 0.133 4.11 -0.396 2.3 0.863 0.064 0.673 0.0184 34.3 -3.09 9.51 0.745 0.128 0.0456 2.72e-09 17100000 -2.32 2.67 0.384 0.415 0.0981 0.000392 3.52 PRS_PLINK_1e.06 TRUE 368.3 Anisometropia Both 0 3 7 sense organs darkseagreen4 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 368.4 Visual field defects Both 3 12 7 sense organs darkseagreen4 12, 3 3, 1 3, 1 3, 0 3, 1 -1.57 2.81 0.576 0.239 0.208 3.06e-07 66.5 -0.347 992 1 0 0.707 0.00069 4730 0.017 30.4 1 0 1.02 0.816 1.06 0.0139 36.5 1 0 1.01 0.895 1.17 PRS_PLINK_1e.06 TRUE 368.9 Subjective visual disturbances Both 3 11 7 sense organs darkseagreen4 11, 3 2, 1 3, 1 2, 1 3, 0 -0.0489 1.19 0.967 0.014 0.952 0.114 15 -0.00137 118 1 0 0.999 0.55 1.83 -0.182 1540 1 0 0.833 0.784 1.81 0.0994 917 1 0 1.1 0.503 4.48 PRS_PLINK_1e.06 TRUE 368.91 Psychophysical visual disturbances Both 0 1 7 sense organs darkseagreen4 1, 0 PRS_PLINK_1e.06 TRUE 369 Infection of the eye Both 8 38 7 sense organs darkseagreen4 38, 8 9, 3 9, 2 9, 1 10, 2 0.0349 0.458 0.939 0.027 1.04 0.352 2.47 0.375 1.56 0.811 0.091 1.45 0.00952 313 0.217 1.45 0.882 0.055 1.24 0.043 90.2 0.0377 1.33 0.977 0.01 1.04 0.00867 20 PRS_PLINK_1e.06 TRUE 369.2 Eye infection, viral Both 1 11 7 sense organs darkseagreen4 11, 1 3, 0 3, 0 2, 1 3, 0 0.16 3.66 0.965 0.015 1.17 0.00385 950 -0.0507 471 1 0 0.951 0.779 1.13 PRS_PLINK_1e.06 TRUE 369.5 Conjunctivitis, infectious Both 6 32 7 sense organs darkseagreen4 32, 6 7, 3 8, 2 8, 0 8, 1 0.126 0.526 0.811 0.091 1.13 0.412 3.48 -0.258 2.12 0.903 0.044 0.772 0.00914 68.1 -1.64 1.71 0.337 0.472 0.194 0.00262 54.5 0.223 1.49 0.881 0.055 1.25 0.076 481 PRS_PLINK_1e.06 TRUE 370 Keratitis Both 4 18 7 sense organs darkseagreen4 18, 4 5, 1 4, 1 4, 2 5, 0 -0.364 0.866 0.675 0.171 0.695 0.0121 4.37 -0.66 1.9 0.728 0.138 0.517 0.0253 7.49 1.37 2.6 0.597 0.224 3.95 0.0485 431 -1.13 51.4 0.982 0.008 0.324 0.302 0.347 PRS_PLINK_1e.06 TRUE 370.1 Corneal ulcer Both 0 6 7 sense organs darkseagreen4 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 370.2 Superficial keratitis Both 2 7 7 sense organs darkseagreen4 7, 2 2, 0 2, 1 1, 0 2, 1 -0.504 342 0.999 0.001 0.604 0.43 0.705 -0.0153 38 1 0 0.985 0.96 3.12 -0.00369 29.7 1 0 0.996 0.927 1.2 PRS_PLINK_1e.06 TRUE 370.3 Keratoconjunctivitis Both 2 8 7 sense organs darkseagreen4 8, 2 1, 0 2, 1 2, 0 2, 1 0.0196 1340 1 0 1.02 0.388 1.93 -0.599 1520 1 0 0.55 0.533 1.91 0.557 4660 1 0 1.75 0.285 52.8 PRS_PLINK_1e.06 TRUE 370.31 Keratoconjunctivitis sicca Both 0 4 7 sense organs darkseagreen4 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 371 Inflammation of the eye Both 11 35 7 sense organs darkseagreen4 35, 11 8, 5 9, 2 8, 0 9, 4 0.0413 0.384 0.914 0.039 1.04 0.52 2.24 -0.477 1.25 0.702 0.153 0.621 0.125 5.16 -0.518 1.48 0.726 0.139 0.596 0.0272 13.2 0.667 1.1 0.546 0.263 1.95 0.288 27.1 PRS_PLINK_1e.06 TRUE 371.1 Uveitis, noninfectious or NOS Both 2 9 7 sense organs darkseagreen4 9, 2 3, 1 2, 0 2, 1 2, 0 0.0141 787 1 0 1.01 0.521 1.61 0.391 1860 1 0 1.48 0.206 1.61 0.00571 3070 1 0 1.01 0.634 1.83 -0.0501 670 1 0 0.951 0.812 1.1 PRS_PLINK_1e.06 TRUE 371.2 Conjunctivitis, noninfectious Both 1 16 7 sense organs darkseagreen4 16, 1 4, 0 4, 0 4, 0 4, 1 0.586 0.866 0.499 0.302 1.8 0.462 15.2 0.508 2.97 0.864 0.063 1.66 1.6 1.72 PRS_PLINK_1e.06 TRUE 371.21 Allergic conjunctivitis Both 1 15 7 sense organs darkseagreen4 15, 1 4, 0 4, 0 3, 0 4, 1 0.722 1.05 0.491 0.309 2.06 0.376 47 1.19 3.85 0.757 0.121 3.29 3.23 3.38 PRS_PLINK_1e.06 TRUE 371.3 Inflammation of eyelids Both 8 25 7 sense organs darkseagreen4 25, 8 7, 4 6, 1 6, 0 6, 3 -0.0855 0.542 0.875 0.058 0.918 0.325 2.4 0.506 1.93 0.793 0.101 1.66 0.0461 63100 -0.816 1.72 0.635 0.197 0.442 7.05e-05 8.83 1.17 1.65 0.48 0.319 3.22 0.177 1150 PRS_PLINK_1e.06 TRUE 372 Disorders of conjunctiva Both 4 13 7 sense organs darkseagreen4 13, 4 3, 2 3, 1 3, 1 3, 0 0.0513 0.885 0.954 0.021 1.05 0.229 5.51 -0.916 914 0.999 0 0.4 0.0165 3.92 0.0179 153 1 0 1.02 0.616 0.546 -0.125 1890 1 0 0.883 0.179 1.79 PRS_PLINK_1e.06 TRUE 374 Other disorders of eyelids Both 9 22 7 sense organs darkseagreen4 22, 9 5, 0 5, 3 5, 2 6, 4 0.933 0.735 0.204 0.69 2.54 0.695 14.1 0.118 4.48 0.979 0.009 1.13 0.000476 3.44e+13 3.2 6.28 0.61 0.215 24.6 0.00845 2.28e+10 1.01 1.69 0.55 0.26 2.75 0.219 242 PRS_PLINK_1e.06 TRUE 374.1 Ectropion or entropion Both 1 5 7 sense organs darkseagreen4 5, 1 1, 0 1, 0 1, 0 1, 1 0.0809 6350 1 0 1.08 0.235 5.9 -0.00261 39.1 1 0 0.997 0.969 1.04 PRS_PLINK_1e.06 TRUE 374.2 Lagophthalmos Both 1 3 7 sense organs darkseagreen4 3, 1 1, 0 1, 1 1, 0 1, 1 0.0962 3740 1 0 1.1 0.491 18.9 PRS_PLINK_1e.06 TRUE 374.3 Ptosis of eyelid Both 2 7 7 sense organs darkseagreen4 7, 2 2, 0 2, 0 1, 1 2, 1 0.292 9.47 0.975 0.011 1.34 1.31 1.45 0.385 2510 1 0 1.47 0.28 2.11 -0.038 179 1 0 0.963 0.718 1.2 PRS_PLINK_1e.06 TRUE 374.6 Dermatochalasis Both 1 9 7 sense organs darkseagreen4 9, 1 3, 0 2, 0 2, 0 2, 1 -0.0641 4.53 0.989 0.005 0.938 0.109 2.19 0.00554 86.3 1 0 1.01 0.806 1.17 PRS_PLINK_1e.06 TRUE 375 Disorders of lacrimal system Both 12 25 7 sense organs darkseagreen4 25, 12 6, 5 6, 1 6, 2 6, 4 -0.0708 0.525 0.893 0.049 0.932 0.372 2.5 -1.85 1.93 0.338 0.471 0.157 6.14e-06 4.21 -0.616 2.35 0.793 0.101 0.54 0.00507 154 0.313 1.5 0.835 0.078 1.37 0.109 19.5 PRS_PLINK_1e.06 TRUE 375.1 Dry eyes Both 14 24 7 sense organs darkseagreen4 24, 14 5, 5 6, 1 6, 3 6, 5 0.215 0.489 0.66 0.18 1.24 0.544 3.16 -2.05 2.47 0.407 0.391 0.129 0.108 5.17 0.543 1.56 0.728 0.138 1.72 0.15 63.2 0.466 1.53 0.76 0.119 1.59 0.129 22.3 PRS_PLINK_1e.06 TRUE 375.2 Epiphora Both 1 7 7 sense organs darkseagreen4 7, 1 2, 0 2, 1 1, 0 2, 0 1.25 1560 0.999 0 3.5 9.97e-08 5e+09 0.00488 329 1 0 1 0.837 1.23 PRS_PLINK_1e.06 TRUE 376 Disorders of the orbit Both 1 4 7 sense organs darkseagreen4 4, 1 1, 0 1, 1 1, 0 1, 0 -0.049 4750 1 0 0.952 0.172 2.27 0.00299 116 1 0 1 0.97 1.04 PRS_PLINK_1e.06 TRUE 377 Disorders of optic nerve and visual pathways Both 3 10 7 sense organs darkseagreen4 10, 3 3, 0 2, 0 2, 1 3, 2 0.646 1.94 0.739 0.131 1.91 0.0226 134 0.132 97.2 0.999 0 1.14 0.405 4.94 2.46 9290000 1 0 11.7 1.13 283 PRS_PLINK_1e.06 TRUE 377.1 Optic atrophy Both 2 3 7 sense organs darkseagreen4 3, 2 1, 0 1, 0 0, 2 1, 0 0.00318 28.4 1 0 1 0.948 1.08 -0.00336 158 1 0 0.997 0.957 1.71 PRS_PLINK_1e.06 TRUE 377.3 Optic neuritis/neuropathy Both 2 5 7 sense organs darkseagreen4 5, 2 2, 0 1, 1 1, 0 1, 1 0.0134 11500000 1 0 1.01 0.359 2.52 0.369 2940 1 0 1.45 0.711 1.51 6.48 56100 1 0 654 8.19e-28 3.28e+23 PRS_PLINK_1e.06 TRUE 378 Strabismus and other disorders of binocular eye movements Both 6 13 7 sense organs darkseagreen4 13, 6 4, 3 3, 1 3, 1 3, 1 -0.379 0.999 0.705 0.152 0.685 0.106 3.35 -2.24 4.02 0.577 0.239 0.106 0.0915 10.1 -4.07 10.1 0.687 0.163 0.017 0.0131 0.0226 4.74 6.47 0.464 0.333 114 0.0247 7560000 PRS_PLINK_1e.06 TRUE 378.1 Strabismus (not specified as paralytic) Both 5 11 7 sense organs darkseagreen4 11, 5 3, 1 3, 2 2, 1 3, 1 0.857 1.32 0.516 0.288 2.36 0.332 70.7 2.37 27100000 1 0 10.7 0.00122 52800 1.08 13100000 1 0 2.96 0.0534 2500 0.201 4640 1 0 1.22 0.0375 10 PRS_PLINK_1e.06 TRUE 378.2 Nystagmus and other irregular eye movements Both 1 3 7 sense organs darkseagreen4 3, 1 1, 1 1, 0 1, 0 1, 1 1.01 29900 1 0 2.75 0.0173 18.2 0.616 19200 1 0 1.85 0.273 4.79 0.0582 18800 1 0 1.06 0.14 239 PRS_PLINK_1e.06 TRUE 378.5 Paralytic strabismus Both 1 3 7 sense organs darkseagreen4 3, 1 1, 0 1, 0 1, 1 1, 0 -0.113 793 1 0 0.893 0.7 1.04 0.00191 23.2 1 0 1 0.991 1 PRS_PLINK_1e.06 TRUE 379 Other disorders of eye Both 19 26 7 sense organs darkseagreen4 26, 19 6, 9 6, 3 6, 3 7, 4 -0.153 0.396 0.699 0.156 0.858 0.413 1.73 -0.462 0.998 0.643 0.191 0.63 0.111 3.31 -1.29 1.24 0.296 0.529 0.274 0.0212 1.94 -0.841 1.05 0.422 0.375 0.431 0.0561 2.53 PRS_PLINK_1e.06 TRUE 379.1 Scleritis and episcleritis Both 0 3 7 sense organs darkseagreen4 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 379.2 Disorders of vitreous body Both 16 16 7 sense organs darkseagreen4 16, 16 4, 8 4, 2 4, 1 4, 5 -0.18 0.554 0.746 0.127 0.836 0.297 2.21 -0.391 1.58 0.805 0.094 0.676 0.0504 8.43 -3.23 2.6 0.213 0.671 0.0394 1.04e-08 1.25 0.455 1.5 0.762 0.118 1.58 0.129 72.9 PRS_PLINK_1e.06 TRUE 379.3 Aphakia and other disorders of lens Both 0 5 7 sense organs darkseagreen4 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 379.4 Anomalies of pupillary function Both 1 2 7 sense organs darkseagreen4 2, 1 1, 1 1, 0 1, 1 1, 0 -0.0448 2970 1 0 0.956 0.378 1.66 0.000835 51.7 1 0 1 0.988 1.01 PRS_PLINK_1e.06 TRUE 379.5 Disorders of iris and ciliary body Both 0 3 7 sense organs darkseagreen4 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 379.9 Pain, swelling or discharge of eye Both 6 18 7 sense organs darkseagreen4 18, 6 5, 0 4, 2 4, 3 5, 1 0.256 1.26 0.839 0.076 1.29 0.159 12.7 -0.14 177 0.999 0 0.869 0.616 1.1 2.9 13.1 0.825 0.084 18.1 8.1e-13 4.62e+16 0.315 725 1 0 1.37 0.476 1.78 PRS_PLINK_1e.06 TRUE 380 Disorders of external ear Both 6 22 7 sense organs darkseagreen4 22, 6 6, 4 5, 0 5, 0 6, 2 -0.242 0.743 0.744 0.128 0.785 0.171 3.34 -2.37 3.82 0.536 0.271 0.0938 2.74e-05 20.1 -1.53 3.26 0.639 0.194 0.217 2.82e-06 2890 -0.128 2.04 0.95 0.022 0.88 0.0104 564 PRS_PLINK_1e.06 TRUE 380.1 Otitis externa Both 2 26 7 sense organs darkseagreen4 26, 2 6, 0 6, 1 6, 1 7, 0 0.607 0.877 0.489 0.311 1.83 0.391 714 0.862 2.29 0.706 0.151 2.37 0.0592 364 0.452 2.37 0.849 0.071 1.57 0.00769 223 PRS_PLINK_1e.06 TRUE 380.4 Impacted cerumen Both 6 28 7 sense organs darkseagreen4 28, 6 7, 4 7, 0 7, 0 7, 2 -0.359 0.745 0.63 0.201 0.698 0.153 3.18 -0.305 2.31 0.895 0.048 0.737 0.000124 723 -3.2 2.37 0.176 0.754 0.0406 0.000241 3.73 -0.244 1.7 0.886 0.053 0.783 0.000399 92.7 PRS_PLINK_1e.06 TRUE 381 Otitis media and Eustachian tube disorders Both 7 50 7 sense organs darkseagreen4 50, 7 13, 2 12, 1 12, 2 13, 2 -0.0128 0.501 0.98 0.009 0.987 0.349 3.61 -0.107 1.64 0.948 0.023 0.898 0.0284 23.1 -0.796 1.12 0.479 0.32 0.451 0.0275 14.9 0.155 1.21 0.898 0.047 1.17 0.0675 23.6 PRS_PLINK_1e.06 TRUE 381.1 Otitis media Both 5 45 7 sense organs darkseagreen4 45, 5 12, 2 11, 1 11, 2 11, 0 -0.243 0.509 0.633 0.199 0.784 0.23 2.87 -0.327 1.42 0.818 0.087 0.721 0.0246 22.6 -0.509 1.21 0.674 0.172 0.601 0.0415 8.01 -0.221 1.23 0.858 0.067 0.802 0.0383 9.71 PRS_PLINK_1e.06 TRUE 381.11 Suppurative and unspecified otitis media Both 4 37 7 sense organs darkseagreen4 37, 4 10, 2 9, 1 9, 1 9, 0 -0.236 0.564 0.675 0.171 0.789 0.23 3.95 -0.481 1.7 0.777 0.11 0.618 0.0137 333 -0.7 1.73 0.686 0.164 0.497 0.00545 11.1 -0.473 1.43 0.741 0.13 0.623 0.00234 10.3 PRS_PLINK_1e.06 TRUE 381.2 Eustachian tube disorders Both 4 31 7 sense organs darkseagreen4 31, 4 8, 0 8, 1 7, 1 8, 2 1.62 1.36 0.232 0.634 5.05 0.335 600 1.68 2.7 0.534 0.273 5.36 0.0697 545000 -1.12 2.6 0.665 0.177 0.325 1.8e-05 29.8 0.495 1.57 0.752 0.124 1.64 0.0073 325 PRS_PLINK_1e.06 TRUE 381.3 Mastoiditis & related conditions Both 0 5 7 sense organs darkseagreen4 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 381.9 Otorrhea Both 0 5 7 sense organs darkseagreen4 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 382 Otalgia Both 4 29 7 sense organs darkseagreen4 29, 4 8, 0 7, 3 7, 0 7, 0 -0.492 1.12 0.659 0.181 0.611 0.00184 10.5 0.811 1.61 0.615 0.211 2.25 0.0991 604 PRS_PLINK_1e.06 TRUE 383 Otosclerosis Both 0 4 7 sense organs darkseagreen4 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 384 Other disorders of tympanic membrane Both 1 5 7 sense organs darkseagreen4 5, 1 2, 0 1, 0 1, 0 1, 1 -0.114 1.28e+08 1 0 0.892 0.00254 1.3e+08 -1.13e-05 13200 1 0 1 0.0987 12.4 PRS_PLINK_1e.06 TRUE 384.1 Myringitis Both 0 2 7 sense organs darkseagreen4 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 384.4 Perforation of tympanic membrane Both 1 1 7 sense organs darkseagreen4 1, 1 0.000953 17.1 1 0 1 0.986 1.02 PRS_PLINK_1e.06 TRUE 385 Other disorders of middle ear and mastoid Both 0 6 7 sense organs darkseagreen4 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 385.3 Cholesteatoma Both 0 4 7 sense organs darkseagreen4 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 385.5 Tympanosclerosis and middle ear disease related to otitis media Both 0 3 7 sense organs darkseagreen4 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 386 Vertiginous syndromes and other disorders of vestibular system Both 4 23 7 sense organs darkseagreen4 23, 4 6, 1 6, 1 5, 1 6, 1 -0.622 0.696 0.371 0.43 0.537 0.0598 2.35 -0.556 3.77 0.883 0.054 0.573 0.000662 424 0.649 2.44 0.79 0.102 1.91 0.00498 149 -0.406 2.12 0.848 0.071 0.666 0.0158 62 PRS_PLINK_1e.06 TRUE 386.1 Meniere's disease Both 0 2 7 sense organs darkseagreen4 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 386.2 Peripheral or central vertigo Both 4 17 7 sense organs darkseagreen4 17, 4 5, 2 4, 1 4, 1 4, 0 -0.372 0.822 0.651 0.187 0.689 0.0901 2.63 0.467 3.67 0.899 0.046 1.6 0.0117 1660 -0.0391 2.3 0.986 0.006 0.962 0.00252 56.7 1.25 9.02 0.89 0.051 3.48 7.91e-09 3.82e+08 PRS_PLINK_1e.06 TRUE 386.21 Central origin vertigo Both 3 14 7 sense organs darkseagreen4 14, 3 4, 2 3, 1 3, 0 4, 0 -0.417 0.925 0.652 0.186 0.659 0.0761 4.43 0.393 22.2 0.986 0.006 1.48 1.11 4.88 -2.61 2840 0.999 0 0.0738 0.0159 0.557 -0.0171 2170 1 0 0.983 0.38 1.56 PRS_PLINK_1e.06 TRUE 386.3 Labyrinthitis Both 3 19 7 sense organs darkseagreen4 19, 3 5, 1 5, 2 4, 0 5, 0 -0.734 0.777 0.345 0.462 0.48 0.0146 2.47 -0.193 3.78 0.959 0.018 0.825 0.00101 183 0.032 25.5 0.999 0 1.03 0.0535 28.9 -1.71 4.19 0.684 0.165 0.182 0.000293 108 PRS_PLINK_1e.06 TRUE 386.9 Dizziness and giddiness (Light-headedness and vertigo) Both 12 46 7 sense organs darkseagreen4 46, 12 11, 4 11, 4 11, 2 12, 2 -0.0503 0.359 0.889 0.051 0.951 0.49 1.9 0.266 1.15 0.817 0.088 1.3 0.168 12 0.55 1.35 0.683 0.166 1.73 0.157 110 0.469 1.29 0.715 0.145 1.6 0.157 3580 PRS_PLINK_1e.06 TRUE 388 Other disorders of ear Both 0 7 7 sense organs darkseagreen4 7, 0 2 2 1 2 PRS_PLINK_1e.06 TRUE 389 Hearing loss Both 13 49 7 sense organs darkseagreen4 49, 13 12, 2 12, 5 12, 1 12, 5 0.408 0.424 0.337 0.473 1.5 0.684 3.88 1.33 1.62 0.413 0.384 3.77 0.125 812 0.239 1.21 0.844 0.074 1.27 0.118 190 2.23 1.48 0.131 0.883 9.35 0.51 756 PRS_PLINK_1e.06 TRUE 389.1 Sensorineural hearing loss Both 7 26 7 sense organs darkseagreen4 26, 7 7, 3 6, 1 6, 1 7, 2 0.336 0.624 0.591 0.229 1.4 0.424 4.64 1.16 2.06 0.574 0.241 3.18 0.0944 612 0.521 2.39 0.827 0.082 1.68 0.0268 7360 1.35 1.64 0.41 0.387 3.85 0.316 1950 PRS_PLINK_1e.06 TRUE 389.2 Conductive hearing loss Both 1 11 7 sense organs darkseagreen4 11, 1 2, 0 3, 0 2, 1 3, 0 -0.178 2.19 0.935 0.029 0.837 0.0456 38.5 -0.373 1610 1 0 0.688 0.0558 3.29 PRS_PLINK_1e.06 TRUE 389.3 Degenerative and vascular disorders of ear Both 0 2 7 sense organs darkseagreen4 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 389.4 Tinnitus Both 5 27 7 sense organs darkseagreen4 27, 5 7, 0 7, 1 6, 1 7, 3 0.644 0.681 0.344 0.463 1.9 0.612 15.2 -0.251 1.95 0.898 0.047 0.778 0.0162 189 0.114 1.74 0.948 0.023 1.12 0.0435 789 2.47 2.27 0.276 0.559 11.8 0.44 28600000 PRS_PLINK_1e.06 TRUE 389.5 Disorders of acoustic nerve Both 0 1 7 sense organs darkseagreen4 1, 0 PRS_PLINK_1e.06 TRUE 394 Rheumatic disease of the heart valves Both 1 8 8 circulatory system red 8, 1 2, 1 2, 0 2, 0 2, 0 0.121 9.5 0.99 0.004 1.13 0.165 8.38 0.0293 1060 1 0 1.03 0.891 1.24 0.0245 1680 1 0 1.02 0.0064 6.87 0.152 9920 1 0 1.16 0.602 2.21 PRS_PLINK_1e.06 TRUE 394.1 Mitral valve stenosis and aortic valve stenosis Both 1 1 8 circulatory system red 1, 1 0.0514 67.7 0.999 0 1.05 0.889 1.13 PRS_PLINK_1e.06 TRUE 394.2 Mitral valve disease Both 0 3 8 circulatory system red 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 394.7 Disease of tricuspid valve Both 0 2 8 circulatory system red 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 395 Heart valve disorders Both 4 31 8 circulatory system red 31, 4 7, 1 8, 0 7, 2 8, 1 0.254 0.478 0.595 0.225 1.29 0.544 4.43 -0.455 2.59 0.861 0.065 0.635 0.00471 450 1.35 2.4 0.573 0.242 3.86 0.0599 3.57e+10 0.652 1.6 0.685 0.165 1.92 0.121 8470 PRS_PLINK_1e.06 TRUE 395.1 Nonrheumatic mitral valve disorders Both 2 18 8 circulatory system red 18, 2 5, 1 4, 0 4, 0 5, 1 1.01 1.37 0.458 0.339 2.75 0.157 54.2 0.00835 9.63 0.999 0 1.01 0.972 1.03 3.02 246 0.99 0.004 20.6 13.9 230 -0.313 2.09 0.881 0.055 0.732 0.00985 19.2 PRS_PLINK_1e.06 TRUE 395.2 Nonrheumatic aortic valve disorders Both 2 14 8 circulatory system red 14, 2 4, 0 3, 0 3, 0 4, 2 0.0546 0.945 0.954 0.021 1.06 0.0734 7.09 -0.249 2.14 0.907 0.042 0.78 0.0298 20.4 PRS_PLINK_1e.06 TRUE 395.3 Nonrheumatic tricuspid valve disorders Both 0 4 8 circulatory system red 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 395.4 Nonrheumatic pulmonary valve disorders Both 0 2 8 circulatory system red 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 395.6 Heart valve replaced Both 0 9 8 circulatory system red 9, 0 3 2 2 2 PRS_PLINK_1e.06 TRUE 396 Abnormal heart sounds Both 4 45 8 circulatory system red 45, 4 11, 1 11, 1 11, 1 11, 1 0.452 0.56 0.419 0.377 1.57 0.57 12.1 0.935 1.84 0.611 0.214 2.55 0.0399 99100 0.372 1.7 0.826 0.083 1.45 0.0282 7880 1.27 1.73 0.464 0.333 3.56 0.0602 2280 PRS_PLINK_1e.06 TRUE 401 Hypertension Both 29 35 8 circulatory system red 35, 29 9, 15 9, 3 8, 8 9, 2 -0.377 0.31 0.225 0.649 0.686 0.375 1.21 -1.03 1.07 0.336 0.474 0.357 0.0362 2.49 -0.304 0.735 0.679 0.168 0.738 0.196 2.77 -1.58 1.24 0.203 0.692 0.207 0.0084 1.64 PRS_PLINK_1e.06 TRUE 401.1 Essential hypertension Both 29 35 8 circulatory system red 35, 29 9, 15 9, 3 8, 8 9, 2 -0.377 0.31 0.225 0.649 0.686 0.375 1.21 -1.03 1.07 0.336 0.474 0.357 0.0362 2.49 -0.304 0.735 0.679 0.168 0.738 0.196 2.77 -1.58 1.24 0.203 0.692 0.207 0.0084 1.64 PRS_PLINK_1e.06 TRUE 401.2 Hypertensive heart and/or renal disease Both 1 19 8 circulatory system red 19, 1 5, 1 5, 0 4, 0 5, 0 -0.0927 0.692 0.893 0.049 0.911 0.0903 4.63 -0.429 3.08 0.889 0.051 0.651 0.00162 377 0.177 3.52 0.96 0.018 1.19 1.18 1.21 0.977 5.05 0.847 0.072 2.66 0.00141 7350 PRS_PLINK_1e.06 TRUE 401.21 Hypertensive heart disease Both 0 7 8 circulatory system red 7, 0 2 2 1 2 PRS_PLINK_1e.06 TRUE 401.22 Hypertensive chronic kidney disease Both 1 18 8 circulatory system red 18, 1 5, 1 4, 0 4, 0 5, 0 0.0937 0.768 0.903 0.044 1.1 0.0882 7.31 -0.683 8.05 0.932 0.03 0.505 0.485 0.527 0.177 3.52 0.96 0.018 1.19 1.18 1.21 0.977 5.05 0.847 0.072 2.66 0.00141 7350 PRS_PLINK_1e.06 TRUE 401.3 Other hypertensive complications Both 5 23 8 circulatory system red 23, 5 6, 3 6, 1 5, 1 6, 0 0.0466 0.603 0.938 0.028 1.05 0.292 794 -1.36 2.35 0.562 0.25 0.256 0.00508 14.2 0.255 1.52 0.867 0.062 1.29 1.08 1.6 0.153 3.55 0.966 0.015 1.17 0.00182 302 PRS_PLINK_1e.06 TRUE 411 Ischemic Heart Disease Both 13 34 8 circulatory system red 34, 13 8, 2 8, 3 8, 6 9, 2 0.13 0.367 0.724 0.14 1.14 0.587 2.31 -0.975 1.81 0.59 0.229 0.377 0.0154 13.5 1.26 1.31 0.334 0.477 3.53 0.404 518 0.315 1.35 0.815 0.089 1.37 0.0707 193 PRS_PLINK_1e.06 TRUE 411.1 Unstable angina (intermediate coronary syndrome) Both 0 12 8 circulatory system red 12, 0 3 3 3 3 PRS_PLINK_1e.06 TRUE 411.2 Myocardial infarction Both 5 25 8 circulatory system red 25, 5 7, 0 6, 1 6, 3 6, 1 0.0967 0.514 0.851 0.07 1.1 0.406 3.45 0.0168 2.59 0.995 0.002 1.02 0.00937 1160 1.21 1.93 0.531 0.275 3.35 0.164 8100 0.00823 1.93 0.997 0.001 1.01 0.000904 64.3 PRS_PLINK_1e.06 TRUE 411.3 Angina pectoris Both 3 22 8 circulatory system red 22, 3 6, 0 5, 1 5, 2 6, 0 0.217 0.678 0.749 0.125 1.24 0.186 7.99 0.218 4.57 0.962 0.017 1.24 0.00171 1290 1.04 1.71 0.544 0.264 2.82 0.194 113 PRS_PLINK_1e.06 TRUE 411.4 Coronary atherosclerosis Both 7 31 8 circulatory system red 31, 7 8, 2 8, 2 7, 2 8, 1 -0.19 0.522 0.716 0.145 0.827 0.225 2.46 -1.73 1.95 0.376 0.425 0.177 0.000429 5.63 0.813 1.94 0.676 0.17 2.25 0.0273 8970 -0.0419 1.39 0.976 0.011 0.959 0.0733 21.6 PRS_PLINK_1e.06 TRUE 411.41 Aneurysm and dissection of heart Both 0 3 8 circulatory system red 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 411.8 Other chronic ischemic heart disease, unspecified Both 7 30 8 circulatory system red 30, 7 8, 1 7, 2 7, 2 8, 2 0.157 0.509 0.758 0.12 1.17 0.433 3.12 0.492 2.47 0.842 0.075 1.64 0.0116 2060 1.91 1.92 0.319 0.496 6.74 0.322 8890 -0.0229 1.46 0.987 0.005 0.977 0.0175 56.2 PRS_PLINK_1e.06 TRUE 411.9 Other acute and subacute forms of ischemic heart disease Both 0 4 8 circulatory system red 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 414 Other forms of chronic heart disease Both 4 26 8 circulatory system red 26, 4 7, 1 6, 2 6, 1 7, 0 -0.425 0.61 0.485 0.314 0.654 0.0506 2.47 -1.41 2.28 0.538 0.269 0.245 0.000195 9.54 -0.859 1.59 0.59 0.229 0.424 0.00721 4.37 -0.585 1.57 0.71 0.149 0.557 0.0245 14 PRS_PLINK_1e.06 TRUE 414.2 ASCVD Both 1 10 8 circulatory system red 10, 1 3, 0 2, 1 2, 0 3, 0 0.307 6.51 0.962 0.017 1.36 9.23e-05 106000 0.0526 1800 1 0 1.05 0.426 4.36 PRS_PLINK_1e.06 TRUE 415 Pulmonary heart disease Both 4 33 8 circulatory system red 33, 4 8, 1 8, 2 8, 1 8, 0 -0.382 0.627 0.542 0.266 0.683 0.2 2.6 -1.1 2.19 0.616 0.21 0.333 8.5e-07 432 0.674 1.85 0.715 0.146 1.96 0.0199 1520 -0.0903 1.41 0.949 0.023 0.914 0.0322 17.9 PRS_PLINK_1e.06 TRUE 415.1 Acute pulmonary heart disease Both 1 19 8 circulatory system red 19, 1 4, 0 5, 0 4, 1 5, 0 0.348 1 0.728 0.138 1.42 0.192 27.9 0.144 19600000 1 0 1.15 3.79e-09 757 PRS_PLINK_1e.06 TRUE 415.11 Pulmonary embolism and infarction, acute Both 1 19 8 circulatory system red 19, 1 4, 0 5, 0 4, 1 5, 0 0.348 1 0.728 0.138 1.42 0.192 27.9 0.144 19600000 1 0 1.15 3.79e-09 757 PRS_PLINK_1e.06 TRUE 415.2 Chronic pulmonary heart disease Both 4 20 8 circulatory system red 20, 4 4, 1 5, 2 5, 1 5, 0 0.0767 0.642 0.905 0.043 1.08 0.287 5.12 -1.7 3.97 0.668 0.175 0.183 0.159 0.217 -0.204 1.94 0.917 0.038 0.816 0.0267 26.5 -4.65e-11 52.9 1 0 1 1.43e-06 655000 PRS_PLINK_1e.06 TRUE 415.21 Primary pulmonary hypertension Both 3 9 8 circulatory system red 9, 3 3, 1 2, 2 2, 0 2, 0 -0.403 1.1 0.714 0.146 0.669 0.106 3.61 -0.216 3680 1 0 0.806 0.162 0.208 -0.0422 542 1 0 0.959 0.702 1.14 2.51 9930 1 0 12.4 8.36e-07 22600000 PRS_PLINK_1e.06 TRUE 416 Cardiomegaly Both 1 15 8 circulatory system red 15, 1 4, 1 4, 0 3, 0 4, 0 -0.162 0.956 0.865 0.063 0.85 0.0372 10.3 -4.82e-12 18.8 1 0 1 0.278 1.02 -1.2 11700000 1 0 0.302 0.00309 59.3 -0.647 63.8 0.992 0.004 0.524 0.00128 1.05 PRS_PLINK_1e.06 TRUE 418 Nonspecific chest pain Both 28 35 8 circulatory system red 35, 28 8, 5 9, 12 8, 5 9, 6 -0.0588 0.324 0.856 0.068 0.943 0.509 1.73 0.481 1.2 0.689 0.162 1.62 0.147 26.8 0.0989 1.24 0.936 0.029 1.1 0.116 13.3 0.188 1.1 0.864 0.063 1.21 0.147 9.91 PRS_PLINK_1e.06 TRUE 418.1 Precordial pain Both 4 12 8 circulatory system red 12, 4 3, 3 3, 1 3, 0 3, 0 0.916 2.4 0.703 0.153 2.5 0.0794 4210 -2.93 39.1 0.94 0.027 0.0534 4.79e-06 17.2 -0.691 56.5 0.99 0.004 0.501 0.00645 0.734 0.493 611 0.999 0 1.64 1.46 173 PRS_PLINK_1e.06 TRUE 420 Carditis Both 1 16 8 circulatory system red 16, 1 4, 1 4, 0 4, 0 4, 0 -0.364 0.819 0.657 0.183 0.695 0.1 9.84 -0.487 112 0.997 0.002 0.615 0.124 1.17 0.0824 19.5 0.997 0.001 1.09 3.67e-05 1.15 -0.829 34.4 0.981 0.008 0.437 0.000768 0.482 PRS_PLINK_1e.06 TRUE 420.2 Pericarditis Both 1 7 8 circulatory system red 7, 1 2, 1 2, 0 1, 0 2, 0 -0.416 100 0.997 0.001 0.659 0.674 1.11 0.0274 1200 1 0 1.03 0.875 1.1 0.579 13000 1 0 1.78 0.327 7.06 0.0122 723 1 0 1.01 0.765 2.62 PRS_PLINK_1e.06 TRUE 420.21 Acute pericarditis Both 1 3 8 circulatory system red 3, 1 1, 1 1, 0 1, 0 1, 1 -0.0309 1380 1 0 0.97 0.377 1.53 -0.0188 58 1 0 0.981 0.784 1.69 -0.0111 30.5 1 0 0.989 0.855 1.2 PRS_PLINK_1e.06 TRUE 420.22 Chronic pericarditis Both 1 0 8 circulatory system red 0, 1 PRS_PLINK_1e.06 TRUE 420.3 Endocarditis Both 0 9 8 circulatory system red 9, 0 3 2 2 2 PRS_PLINK_1e.06 TRUE 425 Cardiomyopathy Both 3 19 8 circulatory system red 19, 3 5, 0 5, 0 4, 3 5, 0 0.233 0.772 0.763 0.118 1.26 0.163 9.21 0.423 3.57 0.906 0.043 1.53 0.00459 1520 PRS_PLINK_1e.06 TRUE 425.1 Primary/intrinsic cardiomyopathies Both 3 19 8 circulatory system red 19, 3 5, 0 5, 0 4, 3 5, 0 0.233 0.772 0.763 0.118 1.26 0.163 9.21 0.423 3.57 0.906 0.043 1.53 0.00459 1520 PRS_PLINK_1e.06 TRUE 425.11 Hypertrophic obstructive cardiomyopathy Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_1e.06 TRUE 425.12 Other hypertrophic cardiomyopathy Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_1e.06 TRUE 425.2 Secondary/extrinsic cardiomyopathies Both 0 2 8 circulatory system red 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 425.8 Other cardiomyopathy Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_1e.06 TRUE 426 Cardiac conduction disorders Both 17 33 8 circulatory system red 33, 17 9, 8 8, 1 8, 7 8, 1 -0.217 0.337 0.519 0.285 0.805 0.426 1.49 -1.58 1.4 0.26 0.585 0.207 0.00557 1.85 0.00811 0.804 0.992 0.004 1.01 0.234 4.18 -0.778 1.23 0.529 0.277 0.459 0.0447 4.99 PRS_PLINK_1e.06 TRUE 426.2 Atrioventricular [AV] block Both 0 12 8 circulatory system red 12, 0 3 3 3 3 PRS_PLINK_1e.06 TRUE 426.21 First degree AV block Both 0 10 8 circulatory system red 10, 0 3 2 2 3 PRS_PLINK_1e.06 TRUE 426.23 Second degree AV block Both 0 2 8 circulatory system red 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 426.24 Atrioventricular block, complete Both 0 3 8 circulatory system red 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 426.25 Other heart block Both 0 2 8 circulatory system red 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 426.3 Bundle branch block Both 2 16 8 circulatory system red 16, 2 4, 2 4, 0 4, 0 4, 0 -0.623 0.919 0.498 0.303 0.536 0.00752 6.18 0.29 12.9 0.982 0.008 1.34 1.3 1.37 -1.75 13.1 0.894 0.049 0.174 0.155 0.197 -0.695 5.11 0.892 0.05 0.499 0.000148 827 PRS_PLINK_1e.06 TRUE 426.31 Right bundle branch block Both 2 7 8 circulatory system red 7, 2 2, 1 2, 1 1, 0 2, 0 -0.014 477 1 0 0.986 0.765 1.37 0.0175 2460 1 0 1.02 0.529 2.06 0.00562 920 1 0 1.01 0.814 1.24 0.00186 181 1 0 1 0.556 10.5 PRS_PLINK_1e.06 TRUE 426.32 Left bundle branch block Both 0 11 8 circulatory system red 11, 0 3 3 2 3 PRS_PLINK_1e.06 TRUE 426.4 Anomalous atrioventricular excitation Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_1e.06 TRUE 426.7 Abnormal electrocardiogram [ECG] [EKG] Both 16 31 8 circulatory system red 31, 16 8, 7 8, 1 7, 8 8, 0 -0.306 0.37 0.408 0.389 0.736 0.362 1.43 -1.65 1.49 0.269 0.57 0.192 8.17e-05 1.89 0.19 0.833 0.82 0.086 1.21 0.26 5.28 -1.45 1.62 0.37 0.432 0.234 0.00926 3.23 PRS_PLINK_1e.06 TRUE 426.8 Other cardiac conduction disorders Both 0 5 8 circulatory system red 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 426.9 Cardiac pacemaker/device in situ Both 1 11 8 circulatory system red 11, 1 3, 1 3, 0 2, 0 3, 0 -0.493 1.55 0.75 0.125 0.611 0.0254 7.61 -0.00676 3890 1 0 0.993 0.593 2.72 -0.0226 1860 1 0 0.978 0.569 1.72 -0.213 529 1 0 0.808 0.266 3.13 PRS_PLINK_1e.06 TRUE 426.91 Cardiac pacemaker in situ Both 0 4 8 circulatory system red 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 426.92 Cardiac defibrillator in situ Both 0 6 8 circulatory system red 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 427 Cardiac dysrhythmias Both 25 33 8 circulatory system red 33, 25 9, 8 8, 4 8, 7 8, 5 0.104 0.346 0.763 0.118 1.11 0.589 2.22 -0.547 1.04 0.598 0.224 0.579 0.0803 3.39 0.699 0.98 0.475 0.323 2.01 0.367 16.8 1.18 1.19 0.319 0.496 3.27 0.416 48.5 PRS_PLINK_1e.06 TRUE 427.1 Paroxysmal tachycardia, unspecified Both 4 22 8 circulatory system red 22, 4 6, 1 5, 0 5, 2 6, 1 0.0835 0.522 0.873 0.059 1.09 0.251 4.5 -1.7 3.01 0.573 0.242 0.182 0.157 15.6 0.784 1.83 0.669 0.175 2.19 0.118 41.5 1.06 1.95 0.587 0.231 2.88 0.0648 2100 PRS_PLINK_1e.06 TRUE 427.11 Paroxysmal supraventricular tachycardia Both 2 14 8 circulatory system red 14, 2 4, 1 3, 0 3, 0 4, 1 0.122 0.673 0.856 0.068 1.13 0.346 5.01 -0.168 3480 1 0 0.845 0.436 1.9 0.74 2030 1 0 2.1 2.5 2.98 0.762 2.45 0.756 0.122 2.14 0.0653 141 PRS_PLINK_1e.06 TRUE 427.12 Paroxysmal ventricular tachycardia Both 2 10 8 circulatory system red 10, 2 3, 0 2, 0 2, 2 3, 0 0.276 2.68 0.918 0.037 1.32 0.0064 3010 -0.174 7540 1 0 0.84 0.0998 2.33 PRS_PLINK_1e.06 TRUE 427.2 Atrial fibrillation and flutter Both 4 22 8 circulatory system red 22, 4 6, 1 5, 0 5, 1 6, 2 0.0158 0.559 0.977 0.01 1.02 0.236 8.89 -0.269 5.2 0.959 0.018 0.764 1.63e-05 4030 -0.388 1.96 0.843 0.074 0.678 0.00724 16.6 0.729 1.74 0.675 0.171 2.07 0.0466 521 PRS_PLINK_1e.06 TRUE 427.21 Atrial fibrillation Both 4 20 8 circulatory system red 20, 4 5, 1 5, 0 5, 1 5, 2 0.125 0.656 0.848 0.071 1.13 0.249 9.38 0.0591 797 1 0 1.06 0.846 1.45 -0.294 1.98 0.882 0.055 0.745 0.0235 20 0.798 1.8 0.657 0.182 2.22 0.0543 34.4 PRS_PLINK_1e.06 TRUE 427.22 Atrial flutter Both 1 11 8 circulatory system red 11, 1 3, 0 3, 0 2, 0 3, 1 0.462 1.22 0.704 0.152 1.59 0.267 176 3.17 238 0.989 0.005 23.9 25.7 41.2 PRS_PLINK_1e.06 TRUE 427.3 Other specified cardiac dysrhythmias Both 12 33 8 circulatory system red 33, 12 9, 5 8, 1 8, 4 8, 1 -0.201 0.41 0.624 0.205 0.818 0.372 1.84 -0.207 1.49 0.889 0.051 0.813 0.0232 51.5 0.635 1.2 0.597 0.224 1.89 0.211 51.3 -0.415 1.62 0.798 0.098 0.66 0.0269 12 PRS_PLINK_1e.06 TRUE 427.4 Cardiac arrest and ventricular fibrillation Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_1e.06 TRUE 427.41 Ventricular fibrillation and flutter Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_1e.06 TRUE 427.42 Cardiac arrest Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_1e.06 TRUE 427.5 Arrhythmia (cardiac) NOS Both 5 32 8 circulatory system red 32, 5 8, 2 8, 0 8, 1 8, 2 0.101 0.518 0.846 0.073 1.11 0.401 5.96 -1.14 1.67 0.492 0.308 0.319 0.000141 4.04 0.0619 1.36 0.964 0.016 1.06 0.0196 46.6 1.34 1.49 0.369 0.433 3.81 0.317 7220 PRS_PLINK_1e.06 TRUE 427.6 Premature beats Both 4 19 8 circulatory system red 19, 4 5, 0 5, 0 4, 4 5, 0 -0.423 0.754 0.574 0.241 0.655 0.0366 3.33 1.22 2.12 0.563 0.249 3.4 0.162 281 PRS_PLINK_1e.06 TRUE 427.61 Supraventricular premature beats Both 1 8 8 circulatory system red 8, 1 2, 0 2, 0 2, 0 2, 1 0.000259 35.2 1 0 1 0.115 3.48 -0.0041 523 1 0 0.996 0.483 1.78 PRS_PLINK_1e.06 TRUE 427.7 Tachycardia NOS Both 5 33 8 circulatory system red 33, 5 9, 0 8, 1 8, 3 8, 1 0.169 0.467 0.717 0.144 1.18 0.501 3.7 0.149 1.9 0.938 0.028 1.16 0.0176 59.6 0.904 1.3 0.486 0.313 2.47 0.281 112 0.419 1.53 0.784 0.106 1.52 0.105 293 PRS_PLINK_1e.06 TRUE 427.8 Sinoatrial node dysfunction (Bradycardia) Both 0 6 8 circulatory system red 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 427.9 Palpitations Both 9 31 8 circulatory system red 31, 9 8, 3 8, 1 7, 4 8, 1 0.261 0.476 0.583 0.234 1.3 0.479 4.36 -0.24 1.38 0.863 0.064 0.787 0.0583 55.1 1.09 1.2 0.362 0.442 2.98 0.372 44.6 -0.0494 1.56 0.975 0.011 0.952 0.0261 26 PRS_PLINK_1e.06 TRUE 428 Congestive heart failure; nonhypertensive Both 3 20 8 circulatory system red 20, 3 5, 0 5, 2 5, 1 5, 0 0.0703 0.881 0.936 0.029 1.07 0.0314 103 0.81 3 0.787 0.104 2.25 2.09 2.4 1.36 4.52 0.763 0.118 3.91 0.00261 28500 PRS_PLINK_1e.06 TRUE 428.1 Congestive heart failure (CHF) NOS Both 2 18 8 circulatory system red 18, 2 5, 0 4, 1 4, 1 5, 0 0.0134 0.824 0.987 0.006 1.01 0.122 12.8 -0.0459 41.4 0.999 0 0.955 0.952 0.958 -1.59 11.5 0.89 0.05 0.204 0.178 0.236 PRS_PLINK_1e.06 TRUE 428.2 Heart failure NOS Both 3 18 8 circulatory system red 18, 3 5, 0 4, 1 4, 2 5, 0 0.116 0.906 0.898 0.047 1.12 0.0748 18.1 -0.18 4.83 0.97 0.013 0.836 0.0422 17 1.26 3.75 0.736 0.133 3.53 0.0219 2380 PRS_PLINK_1e.06 TRUE 428.3 Heart failure with reduced EF [Systolic or combined heart failure] Both 2 9 8 circulatory system red 9, 2 3, 0 2, 2 2, 0 2, 0 -0.833 3.23 0.796 0.099 0.435 0.399 22.1 -1.47 721 0.998 0.001 0.23 0.000158 52.1 PRS_PLINK_1e.06 TRUE 428.4 Heart failure with preserved EF [Diastolic heart failure] Both 1 11 8 circulatory system red 11, 1 3, 0 3, 1 2, 0 3, 0 0.0601 1.11 0.957 0.019 1.06 0.185 18.1 -0.0178 1170 1 0 0.982 0.62 1.35 PRS_PLINK_1e.06 TRUE 429 Ill-defined descriptions and complications of heart disease Both 28 35 8 circulatory system red 35, 28 9, 12 9, 9 8, 5 9, 1 -0.488 0.318 0.125 0.905 0.614 0.324 1.08 0.0461 0.849 0.957 0.019 1.05 0.222 5.4 -0.319 0.834 0.702 0.153 0.727 0.156 3.26 -2.49 1.66 0.134 0.872 0.0832 0.000524 1.23 PRS_PLINK_1e.06 TRUE 429.1 Heart transplant/surgery Both 2 5 8 circulatory system red 5, 2 2, 1 1, 0 1, 0 1, 1 0.0191 312 1 0 1.02 0.77 1.59 0.196 2690 1 0 1.22 0.769 1.25 0.06 1520 1 0 1.06 0.765 2.14 -0.0531 1280 1 0 0.948 0.925 1.29 PRS_PLINK_1e.06 TRUE 429.2 Abnormal function study of cardiovascular system Both 15 30 8 circulatory system red 30, 15 8, 9 7, 3 7, 1 8, 1 -0.938 0.427 0.028 1.553 0.391 0.156 0.806 -0.173 1.19 0.885 0.053 0.841 0.0954 7.29 -1.96 1.49 0.187 0.729 0.14 0.000152 1.75 -2.57 1.88 0.173 0.763 0.0765 7.12e-08 1.42 PRS_PLINK_1e.06 TRUE 429.3 Symptoms involving cardiovascular system Both 18 35 8 circulatory system red 35, 18 9, 6 9, 8 8, 4 9, 0 -0.265 0.397 0.504 0.297 0.767 0.36 1.64 0.773 1.02 0.447 0.35 2.17 0.369 20.7 0.29 0.989 0.769 0.114 1.34 0.236 9.97 -0.497 1.71 0.771 0.113 0.608 0.0121 20 PRS_PLINK_1e.06 TRUE 429.9 Cardiac complications, not elsewhere classified Both 1 2 8 circulatory system red 2, 1 1, 0 0, 1 1, 0 1, 0 -0.00753 18.6 1 0 0.992 0.959 1.01 0.000105 32.5 1 0 1 0.999 1 PRS_PLINK_1e.06 TRUE 430 Intracranial hemorrhage Both 1 11 8 circulatory system red 11, 1 3, 1 3, 0 2, 0 3, 0 -0.271 1.72 0.875 0.058 0.763 0.0086 21.9 0.0939 389 1 0 1.1 0.794 2.38 0.319 6110 1 0 1.38 0.576 4.68 0.776 17600000 1 0 2.17 0.00526 6250 PRS_PLINK_1e.06 TRUE 430.1 Subarachnoid hemorrhage Both 0 4 8 circulatory system red 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 430.2 Intracerebral hemorrhage Both 0 3 8 circulatory system red 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 430.3 Subdural hemorrhage Both 0 3 8 circulatory system red 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 433 Cerebrovascular disease Both 8 35 8 circulatory system red 35, 8 9, 1 9, 4 8, 2 9, 0 -0.438 0.428 0.306 0.514 0.645 0.251 1.45 0.913 1.25 0.464 0.333 2.49 0.288 33.7 0.49 1.77 0.782 0.107 1.63 0.0943 135000 0.000697 1.5 1 0 1 0.00304 810 PRS_PLINK_1e.06 TRUE 433.1 Occlusion and stenosis of precerebral arteries Both 3 15 8 circulatory system red 15, 3 4, 2 4, 1 3, 0 4, 0 -0.835 0.866 0.335 0.475 0.434 0.0111 2.08 -2.35 17.4 0.893 0.049 0.0958 8.51e-11 13600000 -0.197 114 0.999 0.001 0.821 5.49 3.1 5.14 14.4 0.722 0.142 171 99.7 281 PRS_PLINK_1e.06 TRUE 433.11 Occlusion of cerebral arteries, with cerebral infarction Both 1 2 8 circulatory system red 2, 1 1, 1 1, 0 1, 1 1, 0 -1.33 941 0.999 0 0.266 0.0311 1.39e+28 0.0115 66.3 1 0 1.01 0.842 1.22 PRS_PLINK_1e.06 TRUE 433.12 Cerebral atherosclerosis Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_1e.06 TRUE 433.2 Occlusion of cerebral arteries Both 2 24 8 circulatory system red 24, 2 6, 1 6, 1 6, 0 6, 0 -0.305 0.686 0.657 0.183 0.737 0.0442 4.24 0.157 1.97 0.936 0.029 1.17 0.00103 50 -0.348 2.23 0.876 0.058 0.706 0.00625 137 -0.288 2.52 0.909 0.041 0.749 0.00922 96.2 PRS_PLINK_1e.06 TRUE 433.21 Cerebral artery occlusion, with cerebral infarction Both 2 23 8 circulatory system red 23, 2 6, 1 6, 1 5, 0 6, 0 -0.294 0.686 0.668 0.175 0.745 0.0422 4.07 -1.02 4.74 0.829 0.082 0.359 1.5e-09 63100 -0.246 2.32 0.916 0.038 0.782 0.00545 141 -0.288 2.52 0.909 0.041 0.749 0.00922 96.2 PRS_PLINK_1e.06 TRUE 433.3 Cerebral ischemia Both 5 25 8 circulatory system red 25, 5 7, 2 6, 2 6, 0 6, 0 -0.623 0.532 0.241 0.617 0.536 0.113 1.55 -0.989 2.28 0.664 0.178 0.372 0.00277 22.4 -1.15 1.91 0.547 0.262 0.318 0.000648 36.9 -0.442 2.05 0.83 0.081 0.643 0.0075 195 PRS_PLINK_1e.06 TRUE 433.31 Transient cerebral ischemia Both 4 21 8 circulatory system red 21, 4 6, 2 5, 1 5, 0 5, 0 -0.486 0.536 0.365 0.438 0.615 0.0911 2.72 -1.62 2.02 0.423 0.374 0.198 0.00585 16.4 -2.43 3.32 0.464 0.333 0.0882 0.000115 19.1 -0.0249 2.07 0.99 0.004 0.975 0.0179 488 PRS_PLINK_1e.06 TRUE 433.5 Cerebral aneurysm Both 1 8 8 circulatory system red 8, 1 2, 1 2, 0 2, 0 2, 0 -0.0599 14 0.997 0.001 0.942 0.0756 11.7 -0.0203 1870 1 0 0.98 0.602 1.54 -0.0731 1170 1 0 0.93 0.507 1.58 0.057 6070 1 0 1.06 0.145 8.67 PRS_PLINK_1e.06 TRUE 433.6 Acute, but ill-defined cerebrovascular disease Both 0 6 8 circulatory system red 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 433.8 Late effects of cerebrovascular disease Both 1 7 8 circulatory system red 7, 1 2, 1 2, 0 1, 0 2, 0 -0.373 85.9 0.997 0.002 0.689 0.749 0.459 -0.965 6270 1 0 0.381 0.357 2.84 -0.042 974 1 0 0.959 0.625 1.18 0.639 56900000 1 0 1.89 0.0557 212 PRS_PLINK_1e.06 TRUE 440 Atherosclerosis Both 2 19 8 circulatory system red 19, 2 5, 1 5, 1 4, 0 5, 0 -0.123 0.855 0.885 0.053 0.884 0.00208 4.71 2.37 3.36 0.48 0.319 10.7 0.000968 956000 -0.474 4.22 0.91 0.041 0.623 0.576 0.719 -0.406 2.17 0.852 0.07 0.666 0.0119 16.8 PRS_PLINK_1e.06 TRUE 440.1 Atherosclerosis of renal artery Both 0 2 8 circulatory system red 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 440.2 Atherosclerosis of the extremities Both 2 16 8 circulatory system red 16, 2 4, 0 4, 2 4, 0 4, 0 -0.137 0.837 0.87 0.06 0.872 0.011 4.62 1.53 3.46 0.659 0.181 4.6 0.0384 2340 PRS_PLINK_1e.06 TRUE 440.21 Atherosclerosis of native arteries of the extremities with ulceration or gangrene Both 0 9 8 circulatory system red 9, 0 3 2 2 2 PRS_PLINK_1e.06 TRUE 440.22 Atherosclerosis of native arteries of the extremities with intermittent claudication Both 2 11 8 circulatory system red 11, 2 3, 0 3, 2 2, 0 3, 0 -0.0257 1.13 0.982 0.008 0.975 0.88 8.27 -0.535 92.8 0.995 0.002 0.586 0.312 0.485 PRS_PLINK_1e.06 TRUE 440.9 Atherosclerosis of aorta Both 1 3 8 circulatory system red 3, 1 1, 0 1, 0 0, 1 1, 0 0.0768 1810 1 0 1.08 0.748 1.19 -0.00191 675 1 0 0.998 0.973 1.03 PRS_PLINK_1e.06 TRUE 441 Vascular insufficiency of intestine Both 0 8 8 circulatory system red 8, 0 2 2 2 2 PRS_PLINK_1e.06 TRUE 441.1 Acute vascular insufficiency of intestine Both 0 3 8 circulatory system red 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 442 Other aneurysm Both 4 21 8 circulatory system red 21, 4 5, 0 5, 2 5, 2 5, 0 0.391 0.704 0.579 0.238 1.48 0.595 13.8 -2.95 11.9 0.803 0.095 0.0522 0.0411 0.0709 1.71 3 0.567 0.246 5.55 0.0985 5710 PRS_PLINK_1e.06 TRUE 442.1 Aortic aneurysm Both 3 13 8 circulatory system red 13, 3 3, 0 3, 0 3, 3 3, 0 0.0657 1.4 0.963 0.017 1.07 0.0483 38.6 1.05 110 0.992 0.003 2.85 9.9e-05 83100 PRS_PLINK_1e.06 TRUE 442.11 Abdominal aortic aneurysm Both 1 4 8 circulatory system red 4, 1 1, 0 1, 0 1, 1 1, 0 -0.0216 576 1 0 0.979 0.0776 10.1 -0.00428 49.1 1 0 0.996 0.909 1.1 PRS_PLINK_1e.06 TRUE 442.3 Aneurysm of artery of lower extremity Both 0 2 8 circulatory system red 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 442.4 Arterial dissection Both 1 0 8 circulatory system red 0, 1 PRS_PLINK_1e.06 TRUE 442.8 Aneurysm of other specified artery Both 0 3 8 circulatory system red 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 443 Peripheral vascular disease Both 3 28 8 circulatory system red 28, 3 6, 2 7, 0 7, 0 7, 1 -0.303 0.592 0.609 0.215 0.739 0.193 2.16 0.211 2.49 0.933 0.03 1.23 0.00509 2880000 -0.825 1.92 0.667 0.176 0.438 0.00643 4450 0.104 1.65 0.95 0.022 1.11 0.011 545 PRS_PLINK_1e.06 TRUE 443.1 Raynaud's syndrome Both 1 7 8 circulatory system red 7, 1 1, 1 2, 0 1, 0 2, 0 0.2 71.4 0.998 0.001 1.22 0.647 11.2 5.17 17200 1 0 176 2.71e-14 8.9e+15 -15.1 3.5e+09 1 0 2.73e-07 1.15e-24 3.7e+13 0.00673 3350 1 0 1.01 0.122 1.63 PRS_PLINK_1e.06 TRUE 443.7 Peripheral angiopathy in diseases classified elsewhere Both 1 5 8 circulatory system red 5, 1 2, 0 1, 0 1, 0 1, 1 -0.0183 1510 1 0 0.982 0.54 1.34 -9.94e-07 7170 1 0 1 0.306 3.38 PRS_PLINK_1e.06 TRUE 443.8 Other specified peripheral vascular diseases Both 3 27 8 circulatory system red 27, 3 6, 2 7, 0 6, 0 7, 1 -0.303 0.593 0.609 0.215 0.738 0.114 2.16 -0.572 1.97 0.771 0.113 0.564 0.0106 23 -0.891 1.98 0.652 0.186 0.41 0.00561 48.6 0.104 1.65 0.95 0.022 1.11 0.011 545 PRS_PLINK_1e.06 TRUE 443.9 Peripheral vascular disease, unspecified Both 3 23 8 circulatory system red 23, 3 5, 2 6, 0 5, 0 6, 1 -0.859 0.818 0.293 0.532 0.423 0.00231 1.79 -0.509 2.27 0.822 0.085 0.601 0.021 33 -2.52 3.6 0.485 0.314 0.0808 5.55e-06 181 -0.0537 1.81 0.976 0.01 0.948 0.000972 533 PRS_PLINK_1e.06 TRUE 444 Arterial embolism and thrombosis Both 1 13 8 circulatory system red 13, 1 3, 0 3, 1 3, 0 3, 0 0.149 1.43 0.917 0.038 1.16 0.0381 28.6 0.11 613 1 0 1.12 0.685 3.1 PRS_PLINK_1e.06 TRUE 444.1 Arterial embolism and thrombosis of lower extremity artery Both 0 4 8 circulatory system red 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 444.2 Embolism and thrombosis of abdominal aorta Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_1e.06 TRUE 446 Polyarteritis nodosa and allied conditions Both 1 10 8 circulatory system red 10, 1 2, 0 2, 0 2, 1 3, 0 0.217 2.4 0.928 0.032 1.24 0.0206 62.2 -0.187 3900 1 0 0.829 0.685 1.56 PRS_PLINK_1e.06 TRUE 446.4 Wegener's granulomatosis Both 0 3 8 circulatory system red 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 446.5 Giant cell arteritis Both 1 1 8 circulatory system red 1, 1 -0.0207 59.3 1 0 0.98 0.896 1.35 PRS_PLINK_1e.06 TRUE 446.9 Arteritis NOS Both 1 4 8 circulatory system red 4, 1 1, 0 1, 0 1, 1 1, 0 -0.432 9120 1 0 0.649 0.0964 3.29 PRS_PLINK_1e.06 TRUE 447 Other disorders of arteries and arterioles Both 3 23 8 circulatory system red 23, 3 5, 0 6, 2 5, 0 6, 1 0.00968 0.597 0.987 0.006 1.01 0.315 4.28 0.635 2.04 0.755 0.122 1.89 0.0954 56.5 -0.636 5.46 0.907 0.042 0.529 2.95e-07 20400 PRS_PLINK_1e.06 TRUE 447.1 Stricture of artery Both 1 5 8 circulatory system red 5, 1 2, 0 1, 0 1, 0 1, 1 -0.0848 3490 1 0 0.919 0.9 1.32 -3.66e-06 2010 1 0 1 0.781 1.27 PRS_PLINK_1e.06 TRUE 447.7 Aortic ectasia Both 0 11 8 circulatory system red 11, 0 2 3 2 3 PRS_PLINK_1e.06 TRUE 448 Disease of capillaries Both 1 13 8 circulatory system red 13, 1 4, 0 3, 0 3, 1 3, 0 0.319 2.68 0.905 0.043 1.38 0.00317 256 2.69 208 0.99 0.005 14.8 1.06 25 PRS_PLINK_1e.06 TRUE 450 Noninfectious disorders of lymphatic channels Both 1 22 8 circulatory system red 22, 1 6, 0 5, 0 5, 0 6, 1 0.37 0.714 0.604 0.219 1.45 0.421 12.4 0.986 1.89 0.601 0.221 2.68 0.169 616 PRS_PLINK_1e.06 TRUE 451 Phlebitis and thrombophlebitis Both 3 6 8 circulatory system red 6, 3 2, 0 1, 1 1, 1 2, 1 0.518 2380000 1 0 1.68 0.416 5.87 -0.00138 35.3 1 0 0.999 0.88 1.36 -0.726 9050 1 0 0.484 0.283 4.73 0.122 19400 1 0 1.13 0.345 7450 PRS_PLINK_1e.06 TRUE 451.2 Phlebitis and thrombophlebitis of lower extremities Both 2 2 8 circulatory system red 2, 2 1, 0 1, 2 1, 0 1, 2 -0.0666 4810 1 0 0.936 0.118 2.7 -0.692 6950 1 0 0.501 0.255 3.35 PRS_PLINK_1e.06 TRUE 452 Other venous embolism and thrombosis Both 5 30 8 circulatory system red 30, 5 8, 2 7, 2 7, 1 8, 0 -0.987 0.639 0.122 0.912 0.373 0.0503 1.05 -1.31 1.62 0.419 0.377 0.269 0.0101 3.4 -0.834 1.82 0.646 0.19 0.434 2e-04 12.5 -1.02 1.72 0.554 0.257 0.36 3.63e-05 7.64 PRS_PLINK_1e.06 TRUE 452.1 Iatrogenic pulmonary embolism and infarction Both 0 6 8 circulatory system red 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 452.2 Deep vein thrombosis [DVT] Both 4 23 8 circulatory system red 23, 4 6, 1 6, 2 5, 1 6, 0 -0.576 0.704 0.413 0.384 0.562 0.0901 1.93 -0.858 1.64 0.601 0.221 0.424 0.0225 6.05 -0.346 2.72 0.899 0.046 0.707 0.00563 157 -0.0944 5.16 0.985 0.006 0.91 2.47e-05 26700 PRS_PLINK_1e.06 TRUE 452.8 Postphlebitic syndrome Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_1e.06 TRUE 453 Chronic venous hypertension Both 0 3 8 circulatory system red 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 454 Varicose veins Both 5 23 8 circulatory system red 23, 5 6, 0 6, 4 5, 0 6, 1 0.0162 0.963 0.987 0.006 1.02 0.0061 18 1.85 2.3 0.421 0.376 6.37 0.239 46700 0.779 4.14 0.851 0.07 2.18 0.00231 33500 PRS_PLINK_1e.06 TRUE 454.1 Varicose veins of lower extremity Both 4 19 8 circulatory system red 19, 4 5, 0 5, 4 4, 0 5, 0 -0.162 0.973 0.868 0.062 0.85 0.0261 42.2 1.82 2.42 0.452 0.344 6.18 0.179 7780 PRS_PLINK_1e.06 TRUE 454.11 Varicose veins of lower extremity, symptomtic Both 4 15 8 circulatory system red 15, 4 4, 0 4, 4 3, 0 4, 0 0.946 1.89 0.618 0.209 2.58 0.0682 374000 0.967 1.66 0.561 0.251 2.63 0.252 237 PRS_PLINK_1e.06 TRUE 455 Hemorrhoids Both 16 28 8 circulatory system red 28, 16 7, 4 7, 6 7, 2 7, 4 -0.114 0.466 0.807 0.093 0.892 0.365 2.1 1.74 1.4 0.214 0.669 5.67 0.272 2.57e+08 1.81 2.08 0.385 0.414 6.08 0.207 84200 0.947 1.46 0.517 0.286 2.58 0.193 225 PRS_PLINK_1e.06 TRUE 456 Chronic venous insufficiency [CVI] Both 8 24 8 circulatory system red 24, 8 6, 0 6, 5 6, 0 6, 2 -0.448 0.707 0.527 0.278 0.639 0.0695 2.81 2.21 2.38 0.352 0.453 9.11 0.229 13900 -0.17 5.25 0.974 0.011 0.844 0.000258 5.6e+07 PRS_PLINK_1e.06 TRUE 457 Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin Both 1 12 8 circulatory system red 12, 1 3, 1 3, 0 3, 0 3, 0 -0.806 1.46 0.58 0.236 0.447 0.00583 4.62 0.0894 1070 1 0 1.09 0.859 1.79 -0.0184 3950 1 0 0.982 0.723 3.09 0.0121 271 1 0 1.01 0.483 3.09 PRS_PLINK_1e.06 TRUE 457.2 Encounter for long-term (current) use of antiplatelets/antithrombotics Both 0 2 8 circulatory system red 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 457.3 Encounter for long-term (current) use of aspirin Both 1 11 8 circulatory system red 11, 1 3, 1 3, 0 2, 0 3, 0 -0.785 1.47 0.592 0.227 0.456 0.0157 4.2 -0.0871 1080 1 0 0.917 0.194 1.75 -0.0182 4290 1 0 0.982 0.487 3.3 0.0121 271 1 0 1.01 0.483 3.09 PRS_PLINK_1e.06 TRUE 458 Hypotension Both 3 38 8 circulatory system red 38, 3 10, 0 9, 0 9, 1 10, 2 0.391 0.67 0.559 0.252 1.48 0.337 12.9 0.0391 1.64 0.981 0.008 1.04 0.0186 131 0.985 1.5 0.512 0.291 2.68 0.0901 129 PRS_PLINK_1e.06 TRUE 458.1 Orthostatic hypotension Both 0 19 8 circulatory system red 19, 0 5 5 4 5 PRS_PLINK_1e.06 TRUE 458.2 Iatrogenic hypotension Both 0 12 8 circulatory system red 12, 0 3 3 3 3 PRS_PLINK_1e.06 TRUE 458.9 Hypotension NOS Both 3 35 8 circulatory system red 35, 3 9, 0 9, 0 8, 2 9, 1 0.398 0.661 0.547 0.262 1.49 0.37 7.65 0.424 1.53 0.782 0.107 1.53 0.0725 56.9 0.764 1.53 0.617 0.209 2.15 0.0729 84.6 PRS_PLINK_1e.06 TRUE 459 Other disorders of circulatory system Both 9 49 8 circulatory system red 49, 9 13, 3 12, 2 12, 2 12, 1 -0.596 0.445 0.18 0.745 0.551 0.175 1.28 0.245 1.2 0.838 0.077 1.28 0.141 32.5 0.784 1.71 0.647 0.189 2.19 0.0484 1.52e+08 -0.323 1.12 0.772 0.112 0.724 0.0638 8.2 PRS_PLINK_1e.06 TRUE 459.1 Hemorrhage NOS Both 0 11 8 circulatory system red 11, 0 3 3 2 3 PRS_PLINK_1e.06 TRUE 459.7 Blood vessel replaced Both 1 12 8 circulatory system red 12, 1 3, 0 3, 0 3, 1 3, 0 0.231 1.81 0.898 0.047 1.26 0.0558 21.6 0.148 610 1 0 1.16 0.702 3.5 PRS_PLINK_1e.06 TRUE 459.9 Circulatory disease NEC Both 9 46 8 circulatory system red 46, 9 12, 3 11, 2 11, 2 12, 1 -0.634 0.465 0.173 0.763 0.531 0.177 1.26 0.229 1.2 0.849 0.071 1.26 0.142 40.3 0.372 1.65 0.822 0.085 1.45 0.0321 1.13e+08 -0.353 1.13 0.755 0.122 0.703 0.0639 8.18 PRS_PLINK_1e.06 TRUE 464 Acute sinusitis Both 11 34 9 respiratory coral4 34, 11 8, 4 8, 3 8, 3 9, 1 -0.46 0.447 0.303 0.518 0.631 0.255 1.45 0.114 1.31 0.931 0.031 1.12 0.118 15.7 -0.712 1.28 0.578 0.238 0.491 0.0346 10.8 -0.794 1.48 0.591 0.228 0.452 0.0171 5.49 PRS_PLINK_1e.06 TRUE 465 Acute upper respiratory infections of multiple or unspecified sites Both 24 36 9 respiratory coral4 36, 24 8, 9 9, 5 9, 6 9, 4 -0.051 0.291 0.861 0.065 0.95 0.56 1.63 -0.119 0.938 0.899 0.046 0.888 0.169 5.16 -0.337 0.81 0.678 0.169 0.714 0.173 2.93 -0.774 0.923 0.402 0.396 0.461 0.0776 2.32 PRS_PLINK_1e.06 TRUE 465.2 Acute pharyngitis Both 17 37 9 respiratory coral4 37, 17 9, 5 9, 5 9, 4 9, 3 -0.0189 0.313 0.952 0.021 0.981 0.56 1.77 -0.418 1.12 0.709 0.15 0.658 0.0792 4.79 -0.323 0.974 0.74 0.131 0.724 0.13 3.82 -0.665 0.963 0.49 0.31 0.514 0.0853 2.54 PRS_PLINK_1e.06 TRUE 465.4 Acute laryngitis and tracheitis Both 0 3 9 respiratory coral4 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 470 Septal Deviations/Turbinate Hypertrophy Both 2 22 9 respiratory coral4 22, 2 6, 0 5, 0 5, 2 6, 0 0.671 0.781 0.39 0.409 1.96 0.454 586 3.38 3.83 0.377 0.424 29.5 0.0897 33800 PRS_PLINK_1e.06 TRUE 471 Nasal polyps Both 2 5 9 respiratory coral4 5, 2 2, 0 1, 0 1, 1 1, 1 -0.0399 34.3 0.999 0 0.961 0.834 1.06 -0.0267 42.8 1 0 0.974 0.816 1.51 0.0639 2130 1 0 1.07 0.592 2.07 PRS_PLINK_1e.06 TRUE 472 Chronic pharyngitis and nasopharyngitis Both 5 23 9 respiratory coral4 23, 5 6, 1 6, 2 5, 1 6, 1 0.0375 0.812 0.963 0.016 1.04 0.156 33.6 1.32 1.83 0.469 0.329 3.76 0.228 294 0.803 4.41 0.855 0.068 2.23 3.42e-07 8770000 1.86 3.41 0.585 0.233 6.44 0.0245 14800 PRS_PLINK_1e.06 TRUE 473 Diseases of the larynx and vocal cords Both 5 26 9 respiratory coral4 26, 5 7, 1 6, 3 6, 0 7, 0 -0.377 0.588 0.522 0.283 0.686 0.0684 2.26 1.09 1.76 0.538 0.269 2.96 0.189 380 0.112 2.05 0.956 0.019 1.12 0.0141 90 0.0309 1.84 0.987 0.006 1.03 0.00223 37.5 PRS_PLINK_1e.06 TRUE 473.1 Chronic laryngitis Both 0 1 9 respiratory coral4 1, 0 PRS_PLINK_1e.06 TRUE 473.3 Paralysis/spasm of vocal cords or larynx Both 1 4 9 respiratory coral4 4, 1 1, 0 1, 0 1, 1 1, 0 -1.12 1580 0.999 0 0.327 4.77e-07 630000 0.0113 85.4 1 0 1.01 0.969 1.1 PRS_PLINK_1e.06 TRUE 473.4 Voice disturbance Both 3 19 9 respiratory coral4 19, 3 5, 0 5, 2 4, 0 5, 0 -0.348 0.603 0.564 0.249 0.706 0.208 2.19 -0.232 3.63 0.949 0.023 0.793 7.98e-05 296 PRS_PLINK_1e.06 TRUE 474 Acute and chronic tonsillitis Both 3 13 9 respiratory coral4 13, 3 4, 2 3, 1 3, 0 3, 0 0.505 0.895 0.572 0.242 1.66 0.377 22.8 4.19 347 0.99 0.004 66 4.56e-06 8.03e+08 0.26 22700000 1 0 1.3 0.000618 10.7 0.326 365 0.999 0 1.39 1.25e-07 1450000 PRS_PLINK_1e.06 TRUE 474.1 Acute tonsillitis Both 1 8 9 respiratory coral4 8, 1 2, 0 2, 1 2, 0 2, 0 0.278 126 0.998 0.001 1.32 0.167 1.39 0.000113 420 1 0 1 0.843 1.15 PRS_PLINK_1e.06 TRUE 474.2 Chronic tonsillitis and adenoiditis Both 3 8 9 respiratory coral4 8, 3 2, 1 2, 1 2, 1 2, 0 1.06 3.75 0.778 0.109 2.88 2.75 3.01 0.441 2020 1 0 1.55 0.381 2.32 0.152 3710 1 0 1.16 0.292 7.42 -0.294 2450 1 0 0.745 0.021 11.6 PRS_PLINK_1e.06 TRUE 475 Chronic sinusitis Both 11 31 9 respiratory coral4 31, 11 8, 5 8, 2 7, 4 8, 0 -0.286 0.428 0.503 0.298 0.751 0.33 1.66 0.07 1.49 0.963 0.017 1.07 0.0139 36 1.48 1.53 0.333 0.478 4.39 0.386 404 -1.72 1.61 0.286 0.544 0.179 0.00376 2.33 PRS_PLINK_1e.06 TRUE 475.9 Postnasal drip Both 4 7 9 respiratory coral4 7, 4 2, 2 2, 1 1, 1 2, 0 -1.97 4.62 0.669 0.175 0.139 7.26e-05 82.3 0.122 369 1 0 1.13 0.256 5.3 0.377 5990 1 0 1.46 0.275 1.59 0.0533 2500 1 0 1.05 0.38 1.24 PRS_PLINK_1e.06 TRUE 476 Allergic rhinitis Both 24 32 9 respiratory coral4 32, 24 8, 8 8, 4 8, 5 8, 6 -0.0385 0.299 0.897 0.047 0.962 0.559 1.69 -1.27 1.3 0.33 0.481 0.281 0.0181 2.86 -0.536 0.906 0.554 0.256 0.585 0.109 2.71 0.852 1.05 0.417 0.38 2.34 0.369 34.6 PRS_PLINK_1e.06 TRUE 477 Epistaxis or throat hemorrhage Both 1 11 9 respiratory coral4 11, 1 3, 0 3, 1 2, 0 3, 0 -0.705 1.85 0.703 0.153 0.494 0.00647 8.08 0.266 59200000 1 0 1.3 0.02 46.1 PRS_PLINK_1e.06 TRUE 478 Throat pain Both 1 5 9 respiratory coral4 5, 1 2, 1 1, 0 1, 0 1, 0 -0.00257 37 1 0 0.997 0.0857 22.1 9.65 12900 0.999 0 15500 7.97e-18 5.11e+29 -0.857 19100 1 0 0.425 0.232 6.81 0.511 8550 1 0 1.67 1.39e-05 7160000 PRS_PLINK_1e.06 TRUE 479 Other upper respiratory disease Both 11 32 9 respiratory coral4 32, 11 8, 3 8, 2 8, 5 8, 1 -0.0237 0.427 0.956 0.02 0.977 0.442 2.24 1.06 1.85 0.568 0.246 2.88 0.119 396 6.88 4 0.0856 1.067 975 0.757 14300000 -0.53 1.91 0.781 0.107 0.589 7.22e-07 808 PRS_PLINK_1e.06 TRUE 480 Pneumonia Both 13 43 9 respiratory coral4 43, 13 11, 3 11, 4 10, 3 11, 2 0.0791 0.408 0.846 0.072 1.08 0.496 2.83 -0.487 1.17 0.676 0.17 0.615 0.0299 5.46 0.0711 1.19 0.952 0.021 1.07 0.127 11.3 0.165 1.07 0.877 0.057 1.18 0.154 9.92 PRS_PLINK_1e.06 TRUE 480.1 Bacterial pneumonia Both 5 13 9 respiratory coral4 13, 5 4, 0 3, 3 3, 1 3, 1 0.295 1.19 0.804 0.095 1.34 0.197 10 -2.02 15.3 0.895 0.048 0.132 9.11e-10 44800000 -0.28 113 0.998 0.001 0.756 0.603 0.567 2.57e-13 7.24 1 0 1 0.047 18.9 PRS_PLINK_1e.06 TRUE 480.11 Pneumococcal pneumonia Both 3 5 9 respiratory coral4 5, 3 2, 2 1, 0 1, 0 1, 1 -4 124 0.974 0.011 0.0183 0.0347 1.29 -0.0138 57.3 1 0 0.986 0.786 1.1 0.398 2170 1 0 1.49 0.159 3.73 -0.0549 780 1 0 0.947 0.416 1.43 PRS_PLINK_1e.06 TRUE 480.12 Pseudomonal pneumonia Both 1 2 9 respiratory coral4 2, 1 1, 0 1, 1 1, 0 1, 1 0.0214 202 1 0 1.02 0.782 1.36 -0.0131 86.3 1 0 0.987 0.896 1.08 PRS_PLINK_1e.06 TRUE 480.2 Viral pneumonia Both 1 7 9 respiratory coral4 7, 1 2, 0 2, 1 1, 0 2, 0 -0.0576 293 1 0 0.944 0.708 1.17 0.0123 288 1 0 1.01 0.521 1.82 PRS_PLINK_1e.06 TRUE 480.3 Pneumonia due to fungus (mycoses) Both 2 3 9 respiratory coral4 3, 2 1, 1 1, 1 1, 0 1, 1 12.5 125000 1 0 255000 6.59e-09 5.99e+19 -1.81 25100 1 0 0.164 8.35e-07 5410 -0.0237 297 1 0 0.977 0.917 1.04 PRS_PLINK_1e.06 TRUE 480.5 Bronchopneumonia and lung abscess Both 0 1 9 respiratory coral4 1, 0 PRS_PLINK_1e.06 TRUE 481 Influenza Both 4 22 9 respiratory coral4 22, 4 6, 1 5, 2 5, 1 6, 0 -0.0269 0.744 0.971 0.013 0.973 0.0725 8.25 0.363 2.02 0.857 0.067 1.44 0.0178 125 0.56 2.33 0.81 0.091 1.75 0.0316 8240 -0.247 2.18 0.91 0.041 0.781 0.0042 125 PRS_PLINK_1e.06 TRUE 483 Acute bronchitis and bronchiolitis Both 9 35 9 respiratory coral4 35, 9 9, 2 9, 4 8, 1 9, 2 0.13 0.431 0.763 0.118 1.14 0.524 2.66 1.66 1.52 0.275 0.561 5.27 0.291 721 0.843 2.01 0.675 0.17 2.32 0.0433 577 1.28 1.53 0.404 0.394 3.6 0.295 2860 PRS_PLINK_1e.06 TRUE 495 Asthma Both 15 45 9 respiratory coral4 45, 15 11, 4 11, 4 11, 7 11, 0 0.0882 0.346 0.799 0.097 1.09 0.576 2.2 -0.562 1.13 0.619 0.209 0.57 0.00435 18.6 0.582 0.83 0.483 0.316 1.79 0.426 8.67 -0.564 1.63 0.73 0.137 0.569 0.00356 987 PRS_PLINK_1e.06 TRUE 495.1 Chronic obstructive asthma Both 1 3 9 respiratory coral4 3, 1 1, 0 1, 1 1, 0 1, 0 -0.089 7630 1 0 0.915 0.351 1.62 -0.00715 30.6 1 0 0.993 0.898 1.1 PRS_PLINK_1e.06 TRUE 495.11 Chronic obstructive asthma with exacerbation Both 1 3 9 respiratory coral4 3, 1 1, 0 1, 1 1, 0 1, 0 -0.321 13000 1 0 0.725 0.0152 7.97 -0.00715 30.6 1 0 0.993 0.898 1.1 PRS_PLINK_1e.06 TRUE 495.2 Asthma with exacerbation Both 7 26 9 respiratory coral4 26, 7 6, 2 6, 2 6, 1 7, 2 0.0262 0.473 0.956 0.02 1.03 0.458 2.71 -0.0287 1.53 0.985 0.007 0.972 0.0597 16.8 0.248 1.75 0.887 0.052 1.28 0.0129 9300 -1.9 2.09 0.363 0.44 0.15 0.000604 17 PRS_PLINK_1e.06 TRUE 496 Chronic airway obstruction Both 7 31 9 respiratory coral4 31, 7 7, 2 8, 2 7, 3 8, 0 -0.166 0.422 0.693 0.159 0.847 0.327 1.89 0.304 1.53 0.843 0.074 1.36 0.0889 94 -0.635 1.56 0.683 0.165 0.53 3.93e-05 8.49 -0.655 1.48 0.658 0.182 0.519 0.00721 70.7 PRS_PLINK_1e.06 TRUE 496.1 Emphysema Both 1 12 9 respiratory coral4 12, 1 3, 1 3, 0 3, 0 3, 0 -0.396 1.41 0.779 0.108 0.673 0.00949 8.79 -0.017 285 1 0 0.983 0.0171 287 0.264 4980000 1 0 1.3 0.0866 2.6 0.236 3670000 1 0 1.27 0.345 6.87 PRS_PLINK_1e.06 TRUE 496.2 Chronic bronchitis Both 3 22 9 respiratory coral4 22, 3 5, 0 5, 2 5, 1 6, 0 0.479 0.684 0.484 0.315 1.61 0.436 103 0.468 1.88 0.803 0.095 1.6 0.0843 46.8 0.815 3.08 0.791 0.102 2.26 0.00459 1050 PRS_PLINK_1e.06 TRUE 496.21 Obstructive chronic bronchitis Both 2 20 9 respiratory coral4 20, 2 4, 0 5, 1 5, 1 5, 0 0.00147 0.548 0.998 0.001 1 0.288 4.54 0.0583 3.2 0.985 0.006 1.06 0.00555 129 1.6 7.25 0.825 0.083 4.95 0.000113 515000 PRS_PLINK_1e.06 TRUE 496.3 Bronchiectasis Both 4 2 9 respiratory coral4 2, 4 1, 3 0, 1 1, 0 1, 3 -0.114 156 0.999 0 0.892 0.646 1.01 -0.565 1110 1 0 0.568 0.521 1.61 -0.0859 555 1 0 0.918 0.432 1.32 PRS_PLINK_1e.06 TRUE 497 Bronchitis Both 5 28 9 respiratory coral4 28, 5 6, 0 7, 2 7, 3 7, 0 0.233 0.536 0.663 0.178 1.26 0.418 4.82 0.616 2.01 0.759 0.12 1.85 0.0266 94 1.64 2.04 0.42 0.377 5.17 0.0335 2780 PRS_PLINK_1e.06 TRUE 498 Acute bronchospasm Both 2 7 9 respiratory coral4 7, 2 2, 1 2, 0 1, 1 2, 0 0.0675 3100000 1 0 1.07 0.0151 84 -0.031 4280 1 0 0.969 0.32 4.75 -0.0094 74 1 0 0.991 0.91 1.06 0.208 71.2 0.998 0.001 1.23 0.759 1.88 PRS_PLINK_1e.06 TRUE 499 Cystic fibrosis Both 2 5 9 respiratory coral4 5, 2 2, 0 1, 0 1, 0 1, 2 -0.173 20800000 1 0 0.841 0.295 6.76 -0.00568 23.1 1 0 0.994 0.941 1.13 PRS_PLINK_1e.06 TRUE 500 Lung disease due to external agents Both 1 2 9 respiratory coral4 2, 1 1, 1 1, 1 1, 1 1, 1 0.054 58.7 0.999 0 1.06 0.86 1.4 PRS_PLINK_1e.06 TRUE 500.1 Extrinsic allergic alveolitis Both 1 1 9 respiratory coral4 1, 1 0.0274 164 1 0 1.03 0.724 1.55 PRS_PLINK_1e.06 TRUE 501 Pneumonitis due to inhalation of food or vomitus Both 0 10 9 respiratory coral4 10, 0 3 2 2 3 PRS_PLINK_1e.06 TRUE 502 Postinflammatory pulmonary fibrosis Both 2 7 9 respiratory coral4 7, 2 1, 1 2, 1 1, 0 2, 0 -0.0929 122 0.999 0 0.911 0.000522 3380 -15.9 18600 0.999 0 1.22e-07 1.2e-36 3.52e+15 0.00437 22.9 1 0 1 0.962 1.05 0.472 8940000 1 0 1.6 0.00752 141 PRS_PLINK_1e.06 TRUE 503 Pulmonary congestion and hypostasis Both 0 11 9 respiratory coral4 11, 0 3 3 2 3 PRS_PLINK_1e.06 TRUE 504 Other alveolar and parietoalveolar pneumonopathy Both 2 3 9 respiratory coral4 3, 2 0, 1 1, 1 1, 0 0, 1 0.000607 1030 1 0 1 0.122 1.46 0.00368 35.4 1 0 1 0.853 1.06 0.00813 40 1 0 1.01 0.783 1.13 PRS_PLINK_1e.06 TRUE 504.1 Idiopathic fibrosing alveolitis Both 2 1 9 respiratory coral4 1, 2 -0.223 62.3 0.997 0.001 0.8 0.6 1.22 PRS_PLINK_1e.06 TRUE 505 Other pulmonary inflamation or edema Both 4 19 9 respiratory coral4 19, 4 5, 1 5, 1 4, 2 5, 0 -0.708 1.15 0.536 0.27 0.493 8e-05 21.3 0.325 5.05 0.949 0.023 1.38 0.000256 33400000 -0.436 2.33 0.852 0.07 0.647 0.00325 2370 -0.328 9.14 0.971 0.013 0.721 4.18e-08 3.19e+09 PRS_PLINK_1e.06 TRUE 506 Empyema and pneumothorax Both 2 23 9 respiratory coral4 23, 2 6, 1 6, 1 5, 0 6, 0 -0.325 0.643 0.614 0.212 0.723 0.038 5.07 -1.14 2.4 0.635 0.197 0.32 0.00547 29.6 -0.617 2.61 0.813 0.09 0.54 0.00307 68.4 1.26 2.67 0.637 0.196 3.53 0.0407 1550 PRS_PLINK_1e.06 TRUE 507 Pleurisy; pleural effusion Both 1 28 9 respiratory coral4 28, 1 6, 0 7, 0 7, 1 7, 0 0.0509 0.558 0.927 0.033 1.05 0.336 7.24 0.957 1.92 0.619 0.208 2.6 0.097 202 PRS_PLINK_1e.06 TRUE 508 Pulmonary collapse; interstitial and compensatory emphysema Both 1 25 9 respiratory coral4 25, 1 7, 0 6, 1 6, 0 6, 0 -0.151 0.907 0.867 0.062 0.86 0.0349 10.6 -0.136 1.71 0.937 0.028 0.873 0.0325 389 PRS_PLINK_1e.06 TRUE 509 Respiratory failure, insufficiency, arrest Both 5 37 9 respiratory coral4 37, 5 9, 2 9, 1 9, 1 9, 1 -0.142 0.49 0.772 0.112 0.868 0.297 2.43 -0.819 2.26 0.717 0.144 0.441 0.000111 56.8 0.229 1.36 0.866 0.062 1.26 0.0321 44.6 0.925 1.51 0.54 0.268 2.52 0.187 8820 PRS_PLINK_1e.06 TRUE 509.1 Respiratory failure Both 1 24 9 respiratory coral4 24, 1 5, 0 6, 0 6, 0 6, 1 0.315 0.587 0.592 0.228 1.37 0.488 21 0.787 1.76 0.654 0.184 2.2 0.114 35.1 PRS_PLINK_1e.06 TRUE 509.2 Respiratory insufficiency Both 0 14 9 respiratory coral4 14, 0 4 3 3 4 PRS_PLINK_1e.06 TRUE 509.3 Pulmonary insufficiency or respiratory failure following trauma and surgery Both 1 13 9 respiratory coral4 13, 1 4, 0 3, 0 3, 1 3, 0 -0.614 1.3 0.637 0.196 0.541 0.0323 3.82 -0.129 847 1 0 0.879 0.28 1.54 PRS_PLINK_1e.06 TRUE 509.8 Dependence on respirator [Ventilator] or supplemental oxygen Both 3 19 9 respiratory coral4 19, 3 4, 2 5, 1 4, 0 5, 0 -1.05 0.835 0.21 0.678 0.351 0.0327 1.44 -0.148 3.19 0.963 0.016 0.862 0.0074 1800 -1.33 5.43 0.807 0.093 0.265 3.37e-05 639 1.56 4.23 0.713 0.147 4.74 0.00576 3590 PRS_PLINK_1e.06 TRUE 510 Other diseases of lung Both 9 40 9 respiratory coral4 40, 9 9, 0 10, 3 10, 2 10, 4 0.495 0.429 0.249 0.605 1.64 0.766 4.46 1.29 2.16 0.551 0.259 3.63 0.0618 209 1.95 2.05 0.342 0.466 7.02 0.237 33100 1.87 1.39 0.178 0.75 6.52 0.751 469 PRS_PLINK_1e.06 TRUE 510.2 Lung transplant Both 0 2 9 respiratory coral4 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 512 Other symptoms of respiratory system Both 31 33 9 respiratory coral4 33, 31 8, 9 8, 15 8, 5 8, 2 -0.275 0.291 0.345 0.462 0.76 0.436 1.29 0.587 0.824 0.477 0.322 1.8 0.425 8.29 -0.298 0.829 0.72 0.143 0.743 0.169 3.11 -2.31 1.81 0.2 0.699 0.0988 0.000814 2.11 PRS_PLINK_1e.06 TRUE 512.1 Wheezing Both 5 16 9 respiratory coral4 16, 5 3, 1 4, 2 4, 1 4, 1 0.339 0.723 0.639 0.194 1.4 0.373 9.17 0.00371 894 1 0 1 0.165 1.67 -0.581 4010 1 0 0.559 2.79e-08 1300000 -0.145 125 0.999 0 0.865 0.257 0.703 PRS_PLINK_1e.06 TRUE 512.2 Painful respiration Both 5 25 9 respiratory coral4 25, 5 6, 3 6, 2 6, 0 6, 0 -0.52 0.441 0.239 0.621 0.595 0.25 1.28 -0.126 1.46 0.932 0.031 0.882 0.0872 10.2 -2.29 1.94 0.24 0.62 0.102 3.85e-05 1.82 -2 2.27 0.379 0.421 0.135 0.000165 3.59 PRS_PLINK_1e.06 TRUE 512.3 Abnormal chest sounds Both 0 3 9 respiratory coral4 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 512.7 Shortness of breath Both 14 33 9 respiratory coral4 33, 14 8, 3 8, 8 8, 3 8, 0 -0.182 0.346 0.599 0.223 0.834 0.439 1.6 1.09 1.16 0.348 0.458 2.96 0.445 32.4 -0.303 1.1 0.782 0.107 0.738 0.084 4.81 -0.146 2.09 0.944 0.025 0.864 0.000219 1360 PRS_PLINK_1e.06 TRUE 512.8 Cough Both 22 33 9 respiratory coral4 33, 22 8, 7 8, 10 8, 4 8, 1 -0.208 0.314 0.508 0.295 0.812 0.45 1.45 0.349 0.934 0.709 0.149 1.42 0.286 8.01 -0.508 0.965 0.598 0.223 0.601 0.0973 3.08 0.918 1.94 0.636 0.197 2.5 0.0406 13100 PRS_PLINK_1e.06 TRUE 512.9 Other dyspnea Both 18 33 9 respiratory coral4 33, 18 8, 3 8, 10 8, 4 8, 1 -0.261 0.335 0.437 0.36 0.77 0.408 1.44 1.06 1.11 0.338 0.471 2.9 0.46 27 0.277 0.961 0.773 0.112 1.32 0.25 7.38 -0.146 2.09 0.944 0.025 0.864 0.000219 1360 PRS_PLINK_1e.06 TRUE 513 Respiratory abnormalities Both 21 43 9 respiratory coral4 43, 21 10, 3 11, 8 10, 8 11, 2 -0.0533 0.315 0.866 0.063 0.948 0.517 1.74 0.508 1.09 0.642 0.193 1.66 0.268 15.1 0.749 0.93 0.42 0.376 2.12 0.39 12.7 0.229 1.51 0.88 0.056 1.26 0.0119 79400 PRS_PLINK_1e.06 TRUE 513.3 Hypoventilation Both 1 10 9 respiratory coral4 10, 1 3, 0 2, 0 2, 1 3, 0 0.311 1.31 0.813 0.09 1.36 0.0266 20.6 -0.339 18800000 1 0 0.712 0.215 2.29 PRS_PLINK_1e.06 TRUE 513.31 Apnea Both 1 5 9 respiratory coral4 5, 1 2, 0 1, 0 1, 0 1, 1 1.36 1920 0.999 0 3.91 2.18 7.71 -0.0509 7110 1 0 0.95 0.251 2.38 PRS_PLINK_1e.06 TRUE 513.32 Orthopnea Both 0 2 9 respiratory coral4 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 513.4 Hyperventilation Both 1 2 9 respiratory coral4 2, 1 1, 1 1, 1 1, 1 1, 1 -0.0116 59.1 1 0 0.988 0.938 1.06 PRS_PLINK_1e.06 TRUE 513.8 Disorders of diaphragm Both 0 3 9 respiratory coral4 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 514 Abnormal findings examination of lungs Both 6 41 9 respiratory coral4 41, 6 10, 0 10, 1 10, 3 10, 2 0.174 0.502 0.729 0.138 1.19 0.456 4.6 0.1 2.12 0.962 0.017 1.11 0.00275 906 1.14 1.64 0.488 0.312 3.12 0.142 5230 0.798 1.39 0.565 0.248 2.22 0.0897 407 PRS_PLINK_1e.06 TRUE 514.1 Abnormal results of function study of pulmonary system Both 0 2 9 respiratory coral4 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 514.2 Solitary pulmonary nodule Both 3 25 9 respiratory coral4 25, 3 7, 0 6, 0 6, 3 6, 0 0.00513 0.607 0.993 0.003 1.01 0.154 19.8 1.29 2.58 0.616 0.21 3.64 0.0113 4180 PRS_PLINK_1e.06 TRUE 516 Abnormal sputum Both 3 10 9 respiratory coral4 10, 3 3, 0 2, 0 2, 2 3, 1 0.648 1.43 0.651 0.186 1.91 0.208 117 0.369 2100 1 0 1.45 0.616 5.51 -0.0935 585 1 0 0.911 0.747 1.36 PRS_PLINK_1e.06 TRUE 516.1 Hemoptysis Both 3 11 9 respiratory coral4 11, 3 3, 0 3, 1 2, 1 3, 1 0.312 1.34 0.816 0.088 1.37 0.0621 1540 0.145 2250 1 0 1.16 0.338 5.19 -1.08 1810 1 0 0.34 6.3e-05 4660 0.0313 1140 1 0 1.03 0.878 2.73 PRS_PLINK_1e.06 TRUE 519 Other diseases of respiratory system, not elsewhere classified Both 8 54 9 respiratory coral4 54, 8 13, 2 13, 2 13, 4 14, 0 0.256 0.493 0.603 0.219 1.29 0.488 4.74 -1.15 1.79 0.522 0.282 0.318 2.76e-05 10.7 -0.463 1.45 0.749 0.125 0.629 0.0181 30.1 -0.209 1.26 0.869 0.061 0.812 0.0212 57.8 PRS_PLINK_1e.06 TRUE 519.1 Tracheostomy complications Both 0 1 9 respiratory coral4 1, 0 PRS_PLINK_1e.06 TRUE 519.2 Respiratory complications Both 0 4 9 respiratory coral4 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 519.8 Other diseases of respiratory system, NEC Both 4 23 9 respiratory coral4 23, 4 6, 0 6, 2 5, 2 6, 0 -0.0142 0.723 0.984 0.007 0.986 0.0637 7.43 0.107 2.17 0.961 0.017 1.11 0.025 418 1.49 2.9 0.606 0.217 4.45 0.0597 32900 PRS_PLINK_1e.06 TRUE 519.9 Symptoms involving respiratory system and other chest symptoms Both 6 43 9 respiratory coral4 43, 6 10, 0 11, 1 10, 4 11, 1 0.529 0.522 0.311 0.508 1.7 0.635 12.3 0.144 1.95 0.941 0.026 1.16 0.0137 2420 1.79 1.49 0.228 0.642 6 0.5 1540 0.727 1.38 0.599 0.223 2.07 0.106 1340 PRS_PLINK_1e.06 TRUE 520 Disorders of tooth development Both 0 8 10 digestive chartreuse4 8, 0 1 2 2 2 PRS_PLINK_1e.06 TRUE 520.1 Hereditary disturbances in tooth structure Both 0 5 10 digestive chartreuse4 5, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 520.2 Disturbances in tooth eruption Both 0 9 10 digestive chartreuse4 9, 0 3 2 2 2 PRS_PLINK_1e.06 TRUE 521 Diseases of hard tissues of teeth Both 0 13 10 digestive chartreuse4 13, 0 3 3 3 3 PRS_PLINK_1e.06 TRUE 521.1 Dental caries Both 0 12 10 digestive chartreuse4 12, 0 2 3 3 3 PRS_PLINK_1e.06 TRUE 522 Diseases of pulp and periapical tissues Both 1 7 10 digestive chartreuse4 7, 1 2, 1 2, 0 1, 0 2, 0 -0.176 104 0.999 0.001 0.839 0.0273 40 -0.0275 1910 1 0 0.973 0.573 1.57 0.018 1380 1 0 1.02 0.712 1.53 0.00409 28 1 0 1 0.89 1.09 PRS_PLINK_1e.06 TRUE 522.5 Periapical abscess Both 1 5 10 digestive chartreuse4 5, 1 2, 1 1, 0 1, 0 1, 0 -0.0286 608 1 0 0.972 0.515 1.16 -0.0891 403 1 0 0.915 0.539 1.44 -0.835 4320 1 0 0.434 0.0189 4.69 0.0381 391 1 0 1.04 0.683 1.08 PRS_PLINK_1e.06 TRUE 523 Gingival and periodontal diseases Both 0 10 10 digestive chartreuse4 10, 0 2 2 2 3 PRS_PLINK_1e.06 TRUE 523.1 Gingivitis Both 0 3 10 digestive chartreuse4 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 523.3 Periodontitis (acute or chronic) Both 0 4 10 digestive chartreuse4 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 523.31 Acute periodontitis Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 523.32 Chronic periodontitis Both 0 1 10 digestive chartreuse4 1, 0 PRS_PLINK_1e.06 TRUE 524 Dentofacial anomalies, including malocclusion Both 2 6 10 digestive chartreuse4 6, 2 2, 0 1, 0 1, 0 2, 2 0.0118 39.1 1 0 1.01 0.943 1.1 1.16 13600000 1 0 3.2 0.00372 1110 PRS_PLINK_1e.06 TRUE 524.3 Anomalies of tooth position/malocclusion Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 525 Other diseases of the teeth and supporting structures Both 1 17 10 digestive chartreuse4 17, 1 4, 1 4, 0 4, 0 4, 0 -0.425 0.794 0.592 0.227 0.654 0.122 4.54 -0.162 64.3 0.998 0.001 0.85 0.0048 150 -1.53 105 0.988 0.005 0.217 4.86e-07 182 0.0132 245 1 0 1.01 0.637 1.64 PRS_PLINK_1e.06 TRUE 525.1 Loss of teeth or edentulism Both 0 7 10 digestive chartreuse4 7, 0 2 2 1 2 PRS_PLINK_1e.06 TRUE 526 Diseases of the jaws Both 4 37 10 digestive chartreuse4 37, 4 9, 0 9, 1 9, 3 9, 0 -0.302 0.605 0.618 0.209 0.74 0.162 5.97 0.263 1.61 0.87 0.061 1.3 0.021 74.2 0.2 1.85 0.914 0.039 1.22 0.00429 722 PRS_PLINK_1e.06 TRUE 526.1 Cysts of the jaws Both 1 6 10 digestive chartreuse4 6, 1 2, 0 1, 1 1, 0 2, 0 0.128 998 1 0 1.14 0.824 1.23 0.282 1220 1 0 1.33 0.778 1.59 PRS_PLINK_1e.06 TRUE 526.3 Anomalies of jaw size/symmetry Both 1 2 10 digestive chartreuse4 2, 1 1, 0 1, 1 1, 0 1, 1 0.105 398 1 0 1.11 0.655 1.39 0.0267 143 1 0 1.03 0.889 1.28 PRS_PLINK_1e.06 TRUE 526.4 Temporomandibular joint disorders Both 2 20 10 digestive chartreuse4 20, 2 5, 0 5, 1 5, 1 5, 0 -0.197 0.918 0.83 0.081 0.822 0.000134 7.44 0.273 4.31 0.949 0.023 1.31 0.3 4.25 2.18 5.66 0.7 0.155 8.88 0.00839 15800 PRS_PLINK_1e.06 TRUE 526.41 Temporomandibular joint disorder, unspecified Both 2 17 10 digestive chartreuse4 17, 2 5, 0 4, 1 4, 1 4, 0 -1.42 1.77 0.424 0.373 0.243 0.000107 9.18 0.154 3.71 0.967 0.015 1.17 0.246 22.6 -2.98e-14 2.97 1 0 1 0.0149 114 PRS_PLINK_1e.06 TRUE 526.42 Arthralgia/ankylosis of temporomandibular joint Both 1 9 10 digestive chartreuse4 9, 1 3, 0 2, 0 2, 0 2, 1 -3.98e-14 4.85 1 0 1 0.000715 851 1.31 5800 1 0 3.69 0.000919 5970 PRS_PLINK_1e.06 TRUE 526.5 Inflammatory conditions of jaw Both 0 3 10 digestive chartreuse4 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 526.9 Jaw disease NOS Both 0 8 10 digestive chartreuse4 8, 0 1 2 2 2 PRS_PLINK_1e.06 TRUE 527 Diseases of the salivary glands Both 3 18 10 digestive chartreuse4 18, 3 4, 0 4, 1 4, 0 5, 2 0.762 0.801 0.341 0.467 2.14 0.617 26.9 1.79 59.1 0.976 0.011 6.02 1.64 233 0.983 4.28 0.818 0.087 2.67 0.000349 2480 PRS_PLINK_1e.06 TRUE 527.1 Hypertrophy of salivary gland Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 527.2 Sialoadenitis Both 1 5 10 digestive chartreuse4 5, 1 1, 0 1, 0 1, 1 1, 0 0.0502 369 1 0 1.05 0.855 1.31 0.127 1140 1 0 1.14 0.759 2.74 PRS_PLINK_1e.06 TRUE 527.7 Disturbance of salivary secretion Both 2 7 10 digestive chartreuse4 7, 2 2, 0 2, 0 1, 1 2, 1 0.74 40.2 0.985 0.006 2.1 0.022 201 0.146 1130 1 0 1.16 0.664 1.27 0.0942 1360 1 0 1.1 0.069 25 PRS_PLINK_1e.06 TRUE 527.8 Other specified diseases of the salivary glands Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 528 Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue Both 6 34 10 digestive chartreuse4 34, 6 8, 0 8, 1 8, 2 9, 3 0.527 0.666 0.428 0.368 1.69 0.536 17.4 0.0734 2.5 0.977 0.01 1.08 0.00194 192 0.869 2.2 0.693 0.159 2.39 0.021 570 -2.58 2.92 0.376 0.424 0.0755 7.86e-05 192 PRS_PLINK_1e.06 TRUE 528.1 Stomatitis and mucositis Both 1 9 10 digestive chartreuse4 9, 1 3, 0 2, 0 2, 1 2, 0 0.0839 25.9 0.997 0.001 1.09 0.0235 52.4 0.0201 833 1 0 1.02 0.524 2.11 PRS_PLINK_1e.06 TRUE 528.11 Stomatitis and mucositis (ulcerative) Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 528.12 Oral aphthae Both 1 3 10 digestive chartreuse4 3, 1 1, 0 1, 0 1, 1 1, 0 7.13 38900 1 0 1240 1.56e-08 4.34e+16 -0.00968 27.7 1 0 0.99 0.928 1.07 PRS_PLINK_1e.06 TRUE 528.3 Cellulitis and abscess of oral soft tissues Both 0 7 10 digestive chartreuse4 7, 0 2 2 1 2 PRS_PLINK_1e.06 TRUE 528.4 Cysts of oral soft tissues Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 528.5 Diseases of lips Both 1 5 10 digestive chartreuse4 5, 1 1, 0 1, 0 1, 0 1, 1 -0.0809 466 1 0 0.922 0.399 2.04 -0.0264 32.8 0.999 0 0.974 0.938 1.2 PRS_PLINK_1e.06 TRUE 528.6 Leukoplakia of oral mucosa Both 2 2 10 digestive chartreuse4 2, 2 1, 0 0, 1 1, 1 1, 0 3.04 7.26e+08 1 0 21 3.89e-10 1.09e+13 -0.0104 58.8 1 0 0.99 0.855 1.32 -0.00301 29.1 1 0 0.997 0.855 1.34 PRS_PLINK_1e.06 TRUE 528.7 Sialolithiasis Both 0 1 10 digestive chartreuse4 1, 0 PRS_PLINK_1e.06 TRUE 529 Diseases and other conditions of the tongue Both 1 5 10 digestive chartreuse4 5, 1 2, 0 1, 1 1, 0 1, 0 0.0188 257 1 0 1.02 0.346 3.82 0.157 4280 1 0 1.17 0.588 2.81 PRS_PLINK_1e.06 TRUE 529.1 Glossitis Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 529.6 Glossodynia Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 530 Diseases of esophagus Both 26 36 10 digestive chartreuse4 36, 26 8, 6 9, 7 9, 11 9, 2 -0.231 0.282 0.412 0.385 0.794 0.468 1.32 -0.649 1.23 0.596 0.225 0.522 0.038 4.65 0.306 0.823 0.71 0.149 1.36 0.311 6.09 -1.62 1.38 0.241 0.617 0.198 0.00321 1.87 PRS_PLINK_1e.06 TRUE 530.1 Esophagitis, GERD and related diseases Both 25 36 10 digestive chartreuse4 36, 25 8, 6 9, 7 9, 10 9, 2 -0.278 0.287 0.332 0.479 0.757 0.441 1.26 -0.649 1.23 0.596 0.225 0.522 0.038 4.65 0.227 0.832 0.785 0.105 1.25 0.283 5.68 -1.62 1.38 0.241 0.617 0.198 0.00321 1.87 PRS_PLINK_1e.06 TRUE 530.11 GERD Both 24 36 10 digestive chartreuse4 36, 24 8, 6 9, 6 9, 10 9, 2 -0.268 0.287 0.351 0.455 0.765 0.446 1.28 -0.779 1.23 0.527 0.278 0.459 0.0327 4.05 0.227 0.832 0.785 0.105 1.25 0.283 5.68 -1.62 1.38 0.241 0.617 0.198 0.00321 1.87 PRS_PLINK_1e.06 TRUE 530.13 Barrett's esophagus Both 0 10 10 digestive chartreuse4 10, 0 3 2 2 3 PRS_PLINK_1e.06 TRUE 530.14 Reflux esophagitis Both 6 21 10 digestive chartreuse4 21, 6 6, 2 5, 1 5, 3 5, 0 -0.0534 0.482 0.912 0.04 0.948 0.402 3.23 1.52 2.03 0.454 0.343 4.59 0.197 7320 1.13 1.34 0.398 0.4 3.11 0.386 30.5 -0.383 2.17 0.86 0.066 0.682 0.000565 18.2 PRS_PLINK_1e.06 TRUE 530.15 Eosinophilic esophagitis Both 1 5 10 digestive chartreuse4 5, 1 2, 0 1, 0 1, 0 1, 1 0.0758 610 1 0 1.08 0.874 1.64 0.0139 14300 1 0 1.01 3.63e-07 55700 PRS_PLINK_1e.06 TRUE 530.2 Esophageal bleeding (varices/hemorrhage) Both 0 6 10 digestive chartreuse4 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 530.3 Stricture and stenosis of esophagus Both 1 9 10 digestive chartreuse4 9, 1 3, 0 2, 0 2, 0 2, 1 -0.934 3.94 0.813 0.09 0.393 0.368 0.423 -0.0207 3700 1 0 0.979 0.513 2.08 PRS_PLINK_1e.06 TRUE 530.5 Disorders of esophageal motility Both 1 6 10 digestive chartreuse4 6, 1 2, 0 1, 0 1, 0 2, 1 -0.227 570 1 0 0.797 0.0505 10.3 6.19 2.88e+08 1 0 490 0.169 2.78e+12 PRS_PLINK_1e.06 TRUE 530.6 Diverticulum of esophagus, acquired Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 530.7 Gastroesophageal laceration-hemorrhage syndrome Both 2 1 10 digestive chartreuse4 1, 2 -0.015 131 1 0 0.985 0.915 1.05 PRS_PLINK_1e.06 TRUE 530.9 Heartburn Both 2 21 10 digestive chartreuse4 21, 2 6, 1 5, 0 5, 0 5, 1 0.213 0.745 0.774 0.111 1.24 0.328 8.9 0.77 2.42 0.75 0.125 2.16 0.0274 130 0.886 3.23 0.784 0.106 2.43 0.00176 1140 0.718 1.76 0.684 0.165 2.05 0.159 30.9 PRS_PLINK_1e.06 TRUE 531 Peptic ulcer (excl. esophageal) Both 3 17 10 digestive chartreuse4 17, 3 5, 0 4, 0 4, 1 4, 2 0.266 1.16 0.819 0.087 1.3 0.115 32.8 3.08 72.1 0.966 0.015 21.9 0.302 84.4 -2.97 21.4 0.89 0.051 0.0515 0.0441 0.0596 PRS_PLINK_1e.06 TRUE 531.1 Hemorrhage from gastrointestinal ulcer Both 1 1 10 digestive chartreuse4 1, 1 0.207 2350 1 0 1.23 0.0816 16.8 PRS_PLINK_1e.06 TRUE 531.2 Gastric ulcer Both 3 10 10 digestive chartreuse4 10, 3 3, 0 2, 0 2, 1 3, 2 1.78 3.76 0.637 0.196 5.91 5.39 6.54 -0.272 928 1 0 0.762 0.141 6.94 0.198 2000 1 0 1.22 0.0017 233 PRS_PLINK_1e.06 TRUE 531.3 Duodenal ulcer Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 531.4 Peptic ulcer, site unspecified Both 1 7 10 digestive chartreuse4 7, 1 2, 0 2, 0 1, 0 2, 1 0.318 239 0.999 0 1.37 2.72 8.26 -2.49 6130 1 0 0.0827 1.29e-11 18100000 PRS_PLINK_1e.06 TRUE 531.5 Gastrojejunal ulcer Both 0 1 10 digestive chartreuse4 1, 0 PRS_PLINK_1e.06 TRUE 532 Dysphagia Both 7 34 10 digestive chartreuse4 34, 7 8, 1 8, 3 8, 2 9, 1 0.172 0.457 0.706 0.151 1.19 0.523 3.36 -0.0525 1.48 0.972 0.012 0.949 0.0366 13.1 1.18 1.53 0.44 0.357 3.26 0.308 235 0.0914 1.52 0.952 0.021 1.1 0.0645 1760 PRS_PLINK_1e.06 TRUE 535 Gastritis and duodenitis Both 10 31 10 digestive chartreuse4 31, 10 7, 0 8, 3 7, 3 8, 4 0.749 0.539 0.165 0.783 2.12 0.854 8.2 1.26 1.91 0.509 0.293 3.54 0.101 667 2.38 2.16 0.269 0.57 10.8 0.499 76800 1.2 1.57 0.444 0.353 3.32 0.152 18900 PRS_PLINK_1e.06 TRUE 535.1 Acute gastritis Both 2 11 10 digestive chartreuse4 11, 2 3, 0 3, 0 2, 1 3, 1 -0.345 1.63 0.833 0.079 0.709 0.0151 19 -0.739 4160 1 0 0.478 0.00639 14.3 -0.505 674 0.999 0 0.604 0.0457 5.38 PRS_PLINK_1e.06 TRUE 535.2 Atrophic gastritis Both 3 1 10 digestive chartreuse4 1, 3 -9.55 51300 1 0 7.12e-05 9.75e-16 2.33e+08 PRS_PLINK_1e.06 TRUE 535.6 Duodenitis Both 1 3 10 digestive chartreuse4 3, 1 1, 0 1, 0 0, 1 1, 0 0.36 2260 1 0 1.43 0.748 1.67 -0.0077 57 1 0 0.992 0.885 6.45 PRS_PLINK_1e.06 TRUE 535.8 Other specified gastritis Both 2 7 10 digestive chartreuse4 7, 2 2, 0 2, 0 1, 0 2, 2 -1.01 5.8 0.861 0.065 0.363 0.349 0.377 -0.158 1030 1 0 0.854 0.431 1.43 PRS_PLINK_1e.06 TRUE 535.9 Gastritis and duodenitis, NOS Both 2 15 10 digestive chartreuse4 15, 2 3, 0 4, 1 3, 1 4, 0 0.659 2.31 0.775 0.11 1.93 0.0142 985 -0.198 4680 1 0 0.82 0.539 2.82 -0.0103 2300 1 0 0.99 0.486 1.92 PRS_PLINK_1e.06 TRUE 536 Disorders of function of stomach Both 15 30 10 digestive chartreuse4 30, 15 7, 0 7, 7 7, 4 8, 4 0.252 0.378 0.505 0.296 1.29 0.669 2.75 3.6 2.94 0.22 0.657 36.7 0.259 35300000 0.959 1.71 0.574 0.241 2.61 0.0859 270 1.75 1.52 0.251 0.601 5.74 0.608 3100 PRS_PLINK_1e.06 TRUE 536.3 Gastroparesis Both 6 16 10 digestive chartreuse4 16, 6 4, 0 4, 3 4, 2 4, 1 0.607 0.737 0.41 0.387 1.83 0.551 7.45 2.26 4.6 0.624 0.205 9.54 0.0111 39400 -1.21 6.17 0.845 0.073 0.299 2.58e-05 2960 1.15e-11 39.7 1 0 1 0.000673 1.12 PRS_PLINK_1e.06 TRUE 536.7 Complications of gastrostomy, colostomy and enterostomy Both 2 2 10 digestive chartreuse4 2, 2 1, 0 1, 2 1, 0 1, 2 -0.508 1330 1 0 0.602 0.596 1.7 -0.1 274 1 0 0.904 0.898 1.12 PRS_PLINK_1e.06 TRUE 536.8 Dyspepsia and other specified disorders of function of stomach Both 9 25 10 digestive chartreuse4 25, 9 7, 1 6, 2 6, 4 6, 2 0.333 0.564 0.555 0.256 1.4 0.544 4.6 2.39 3.97 0.548 0.261 10.9 0.0326 18400 1.28 2.75 0.642 0.193 3.59 0.0257 1340 -0.0416 2.04 0.984 0.007 0.959 0.00301 1230 PRS_PLINK_1e.06 TRUE 537 Other disorders of stomach and duodenum Both 12 33 10 digestive chartreuse4 33, 12 8, 1 8, 5 8, 2 8, 4 -0.00749 0.343 0.983 0.008 0.993 0.539 1.87 2.49 2.25 0.269 0.57 12 0.314 96800 1.24 1.72 0.472 0.326 3.46 0.0951 1200 0.561 1.39 0.686 0.164 1.75 0.144 44.4 PRS_PLINK_1e.06 TRUE 537.1 Lesions of stomach and duodenum Both 0 1 10 digestive chartreuse4 1, 0 PRS_PLINK_1e.06 TRUE 539 Bariatric surgery Both 1 27 10 digestive chartreuse4 27, 1 6, 1 7, 0 6, 0 7, 0 -0.106 0.748 0.887 0.052 0.899 0.19 11.6 -1.61 3.82 0.673 0.172 0.2 3.89e-05 60.4 -0.00358 6.65 1 0 0.996 1.1e-06 312000 0.173 3.14 0.956 0.019 1.19 0.00598 602 PRS_PLINK_1e.06 TRUE 540 Appendiceal conditions Both 0 6 10 digestive chartreuse4 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 540.1 Appendicitis Both 0 3 10 digestive chartreuse4 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 540.11 Acute appendicitis Both 0 3 10 digestive chartreuse4 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 550 Abdominal hernia Both 9 49 10 digestive chartreuse4 49, 9 12, 1 12, 5 12, 3 12, 0 -0.174 0.374 0.643 0.192 0.841 0.4 1.89 0.028 1.28 0.983 0.008 1.03 0.0644 13 1.14 1.18 0.333 0.477 3.13 0.432 1580 0.107 1.37 0.938 0.028 1.11 0.0121 96.1 PRS_PLINK_1e.06 TRUE 550.1 Inguinal hernia Both 3 20 10 digestive chartreuse4 20, 3 5, 2 5, 0 5, 1 5, 0 -0.107 0.561 0.849 0.071 0.899 0.274 2.78 -1.24 1.52 0.416 0.38 0.29 0.00511 2.55 -1.92 3.45 0.579 0.237 0.147 0.124 11.8 -1.49 2.49 0.551 0.259 0.226 0.000405 7.32 PRS_PLINK_1e.06 TRUE 550.2 Diaphragmatic hernia Both 5 28 10 digestive chartreuse4 28, 5 6, 3 7, 0 7, 2 7, 0 -0.143 0.516 0.782 0.107 0.867 0.331 2.55 -1.26 1.78 0.481 0.318 0.285 0.00126 5.35 0.024 1.75 0.989 0.005 1.02 0.049 119 -0.947 1.69 0.575 0.24 0.388 0.00841 24.8 PRS_PLINK_1e.06 TRUE 550.3 Femoral hernia Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 550.4 Umbilical hernia Both 1 13 10 digestive chartreuse4 13, 1 4, 0 3, 0 3, 1 3, 0 -0.321 1.13 0.776 0.11 0.725 0.12 7.98 -0.533 12100000 1 0 0.587 6.88e-06 3110 PRS_PLINK_1e.06 TRUE 550.5 Ventral hernia Both 3 22 10 digestive chartreuse4 22, 3 5, 1 5, 1 5, 1 6, 0 -0.12 0.65 0.853 0.069 0.887 0.23 4.37 5.75 11.4 0.613 0.212 314 7.61e-06 466 0.463 2.04 0.82 0.086 1.59 1.4 1.67 -0.55 3.38 0.871 0.06 0.577 4.47e-06 138 PRS_PLINK_1e.06 TRUE 550.6 Incisional hernia Both 0 13 10 digestive chartreuse4 13, 0 3 3 3 3 PRS_PLINK_1e.06 TRUE 555 Inflammatory bowel disease and other gastroenteritis and colitis Both 5 11 10 digestive chartreuse4 11, 5 2, 1 3, 3 2, 0 3, 1 -1.34 1.36 0.325 0.488 0.263 0.205 1.91 -0.144 2350 1 0 0.866 0.00724 6.56 -5.28 2390 0.998 0.001 0.00508 0.00411 5870000 0.467 580 0.999 0 1.59 1.36 2.13 PRS_PLINK_1e.06 TRUE 555.1 Regional enteritis Both 1 9 10 digestive chartreuse4 9, 1 3, 0 2, 1 2, 0 2, 0 0.0968 4.07 0.981 0.008 1.1 0.0295 44.9 -0.0488 584 1 0 0.952 0.616 1.2 PRS_PLINK_1e.06 TRUE 555.2 Ulcerative colitis Both 4 6 10 digestive chartreuse4 6, 4 2, 2 1, 1 1, 0 2, 1 -0.745 35.6 0.983 0.007 0.475 0.00776 933000 0.036 550 1 0 1.04 0.481 2.46 0.0963 8630 1 0 1.1 0.0372 19.1 -0.00243 52.4 1 0 0.998 0.593 4.13 PRS_PLINK_1e.06 TRUE 555.21 Ulcerative colitis (chronic) Both 4 5 10 digestive chartreuse4 5, 4 2, 1 1, 2 1, 0 1, 1 -0.0255 93.3 1 0 0.975 0.694 1.1 0.0557 668 1 0 1.06 0.706 2.3 1.69 7520 1 0 5.42 0.179 12.9 -0.364 3310 1 0 0.695 0.122 2.73 PRS_PLINK_1e.06 TRUE 556 Ulceration of the lower GI tract Both 0 7 10 digestive chartreuse4 7, 0 2 2 1 2 PRS_PLINK_1e.06 TRUE 556.1 Ulceration of intestine Both 0 5 10 digestive chartreuse4 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 556.11 Angiodysplasia of intestine (without mention of hemorrhage) Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 557 Intestinal malabsorption (non-celiac) Both 7 19 10 digestive chartreuse4 19, 7 4, 2 5, 2 4, 2 5, 1 0.112 0.532 0.833 0.079 1.12 0.474 3.09 -1.09 2.88 0.706 0.151 0.338 0.00344 50.6 1.9 2.95 0.519 0.285 6.71 0.0892 796 -0.308 2.27 0.892 0.05 0.735 0.0342 29 PRS_PLINK_1e.06 TRUE 557.1 Celiac disease Both 4 8 10 digestive chartreuse4 8, 4 1, 1 2, 0 2, 1 2, 2 0.389 0.891 0.662 0.179 1.48 0.387 1.65 -0.000185 71.3 1 0 1 0.306 3.24 -0.16 687 1 0 0.853 0.828 1.22 -0.017 282 1 0 0.983 0.891 1.06 PRS_PLINK_1e.06 TRUE 558 Noninfectious gastroenteritis Both 11 23 10 digestive chartreuse4 23, 11 5, 4 6, 5 5, 0 6, 2 -0.131 0.478 0.784 0.106 0.877 0.383 2.19 -1.71 1.5 0.257 0.59 0.182 0.00391 1.97 -2.67 2.69 0.322 0.493 0.0693 0.000269 3.34 0.0609 1.53 0.968 0.014 1.06 0.059 17600 PRS_PLINK_1e.06 TRUE 559 Ileostomy status Both 0 7 10 digestive chartreuse4 7, 0 2 2 1 2 PRS_PLINK_1e.06 TRUE 560 Intestinal obstruction without mention of hernia Both 5 20 10 digestive chartreuse4 20, 5 4, 1 5, 1 5, 2 5, 1 0.403 0.619 0.515 0.288 1.5 0.558 10.1 2.13 11.5 0.853 0.069 8.41 7.17 9.69 2.22 6.72 0.741 0.13 9.23 0.000235 228000 3.33 4.02 0.407 0.391 28 0.0991 26700 PRS_PLINK_1e.06 TRUE 560.1 Paralytic ileus Both 3 9 10 digestive chartreuse4 9, 3 3, 1 2, 1 2, 1 2, 0 -0.682 1.74 0.695 0.158 0.506 0.472 6.16 -0.807 6200 1 0 0.446 0.246 2.89 0.0615 13300 1 0 1.06 0.129 9.58 0.0232 7530 1 0 1.02 0.379 1.2 PRS_PLINK_1e.06 TRUE 560.2 Impaction of intestine Both 2 1 10 digestive chartreuse4 1, 2 -0.0364 1230 1 0 0.964 0.161 2.21 PRS_PLINK_1e.06 TRUE 560.3 Peritoneal or intestinal adhesions Both 0 1 10 digestive chartreuse4 1, 0 PRS_PLINK_1e.06 TRUE 560.4 Other intestinal obstruction Both 2 13 10 digestive chartreuse4 13, 2 3, 0 3, 0 3, 1 3, 1 0.516 1.66 0.756 0.121 1.68 0.00656 56.7 -0.141 9730 1 0 0.869 0.0554 25 -0.321 4570000 1 0 0.725 0.0257 20.8 PRS_PLINK_1e.06 TRUE 561 Symptoms involving digestive system Both 7 21 10 digestive chartreuse4 21, 7 5, 2 5, 3 5, 0 5, 2 -0.187 0.51 0.714 0.146 0.83 0.274 2.02 -0.991 1.59 0.534 0.272 0.371 0.0294 3.86 -1.35 3.69 0.715 0.146 0.26 3e-04 45.9 -0.245 1.5 0.87 0.06 0.783 0.0624 8.1 PRS_PLINK_1e.06 TRUE 562 Diverticulosis and diverticulitis Both 6 21 10 digestive chartreuse4 21, 6 5, 2 5, 2 5, 1 5, 1 -0.0575 0.656 0.93 0.031 0.944 0.0548 10.4 -1.88 4.18 0.652 0.186 0.152 4.46e-05 106 -0.769 2.16 0.721 0.142 0.463 0.0144 179 -2.14 6.39 0.738 0.132 0.118 1.03e-07 4910 PRS_PLINK_1e.06 TRUE 562.1 Diverticulosis Both 6 21 10 digestive chartreuse4 21, 6 5, 2 5, 2 5, 1 5, 1 -0.0575 0.656 0.93 0.031 0.944 0.0548 10.4 -1.88 4.18 0.652 0.186 0.152 4.46e-05 106 -0.769 2.16 0.721 0.142 0.463 0.0144 179 -2.14 6.39 0.738 0.132 0.118 1.03e-07 4910 PRS_PLINK_1e.06 TRUE 562.2 Diverticulitis Both 1 14 10 digestive chartreuse4 14, 1 4, 1 3, 0 3, 0 4, 0 0.762 1.67 0.649 0.188 2.14 0.142 219 0.192 6070 1 0 1.21 0.311 5.8 0.717 373 0.998 0.001 2.05 0.047 8.76 0.32 22.9 0.989 0.005 1.38 0.148 1.43 PRS_PLINK_1e.06 TRUE 564 Functional digestive disorders Both 27 27 10 digestive chartreuse4 27, 27 6, 3 7, 12 6, 6 7, 6 -0.0151 0.304 0.96 0.018 0.985 0.566 1.7 -0.317 1.42 0.824 0.084 0.728 0.0443 9.74 0.816 1.16 0.482 0.317 2.26 0.332 20.5 0.936 1.22 0.442 0.354 2.55 0.363 26 PRS_PLINK_1e.06 TRUE 564.1 Irritable Bowel Syndrome Both 5 23 10 digestive chartreuse4 23, 5 5, 0 6, 1 5, 2 6, 2 0.371 0.515 0.472 0.326 1.45 0.616 5.98 -0.0956 2.6 0.971 0.013 0.909 0.0086 34.7 2.1 3.28 0.523 0.282 8.13 0.0103 70100 1.09 1.77 0.538 0.269 2.97 0.229 172 PRS_PLINK_1e.06 TRUE 564.9 Personal history of diseases of digestive system Both 5 20 10 digestive chartreuse4 20, 5 4, 1 5, 2 5, 1 5, 1 -0.152 0.69 0.826 0.083 0.859 0.0854 2.93 0.828 2.75 0.764 0.117 2.29 0.0305 3930 0.0236 2.38 0.992 0.003 1.02 0.0338 41.1 -0.0851 4.42 0.985 0.007 0.918 9.95e-06 1840 PRS_PLINK_1e.06 TRUE 565 Anal and rectal conditions Both 11 31 10 digestive chartreuse4 31, 11 7, 1 8, 2 7, 3 8, 5 0.515 0.433 0.235 0.629 1.67 0.807 4.7 -0.394 1.68 0.814 0.089 0.675 0.00322 11.5 0.732 1.83 0.69 0.161 2.08 0.0593 97.2 1.8 1.38 0.192 0.717 6.08 0.736 14300 PRS_PLINK_1e.06 TRUE 565.1 Anal and rectal polyp Both 3 9 10 digestive chartreuse4 9, 3 3, 0 2, 1 2, 0 2, 2 0.857 1.29 0.507 0.295 2.36 0.419 24.8 -0.0848 5.03e+08 1 0 0.919 0.0228 29.8 -0.111 3950 1 0 0.895 0.272 3.04 PRS_PLINK_1e.06 TRUE 567 Peritonitis and retroperitoneal infections Both 1 7 10 digestive chartreuse4 7, 1 2, 0 2, 0 1, 0 2, 1 0.675 474 0.999 0 1.96 4.61 2.85 0.423 1240 1 0 1.53 0.772 2.03 PRS_PLINK_1e.06 TRUE 568 Other disorders of peritoneum Both 1 12 10 digestive chartreuse4 12, 1 2, 0 3, 0 3, 1 3, 0 0.0919 1.2 0.939 0.027 1.1 0.0327 17.5 -0.521 2440 1 0 0.594 0.321 3.42 PRS_PLINK_1e.06 TRUE 568.1 Peritoneal adhesions (postoperative) (postinfection) Both 1 9 10 digestive chartreuse4 9, 1 2, 0 2, 0 2, 1 2, 0 -0.98 2.98 0.742 0.129 0.375 0.00197 21.9 -0.0293 36.7 0.999 0 0.971 0.886 1.43 PRS_PLINK_1e.06 TRUE 569 Other disorders of intestine Both 18 39 10 digestive chartreuse4 39, 18 9, 1 10, 9 9, 4 10, 4 0.274 0.324 0.399 0.399 1.31 0.743 2.51 3.8 2.26 0.092 1.036 44.8 1.35 56100 1.03 1.32 0.437 0.36 2.8 0.347 73.7 1.48 1.22 0.226 0.645 4.39 0.591 113 PRS_PLINK_1e.06 TRUE 569.1 Toxic gastroenteritis and colitis Both 0 3 10 digestive chartreuse4 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 569.2 Gastrointestinal complications Both 2 17 10 digestive chartreuse4 17, 2 4, 1 4, 1 4, 0 4, 0 -0.214 0.808 0.791 0.102 0.808 0.16 11.2 -0.0542 10.9 0.996 0.002 0.947 0.318 0.964 -0.0419 2990000 1 0 0.959 0.0798 10.1 -0.0445 13.8 0.997 0.001 0.956 0.871 1.03 PRS_PLINK_1e.06 TRUE 571 Chronic liver disease and cirrhosis Both 9 33 10 digestive chartreuse4 33, 9 8, 3 8, 0 8, 3 8, 3 0.0467 0.388 0.904 0.044 1.05 0.521 2.23 -2.77 2.64 0.295 0.531 0.0626 5.44e-05 3.95 -0.249 1.36 0.855 0.068 0.78 0.0757 6.23 0.259 1.24 0.834 0.079 1.3 0.137 15 PRS_PLINK_1e.06 TRUE 571.5 Other chronic nonalcoholic liver disease Both 9 34 10 digestive chartreuse4 34, 9 8, 3 8, 0 8, 3 9, 3 0.0178 0.388 0.963 0.016 1.02 0.502 2.16 -2.77 2.64 0.295 0.531 0.0626 5.44e-05 3.95 -0.249 1.36 0.855 0.068 0.78 0.0757 6.23 0.175 1.25 0.888 0.051 1.19 0.0968 13.1 PRS_PLINK_1e.06 TRUE 571.51 Cirrhosis of liver without mention of alcohol Both 0 14 10 digestive chartreuse4 14, 0 4 3 3 4 PRS_PLINK_1e.06 TRUE 571.6 Primary biliary cirrhosis Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 571.8 Liver abscess and sequelae of chronic liver disease Both 1 12 10 digestive chartreuse4 12, 1 3, 0 3, 0 3, 1 3, 0 -0.63 2.71 0.816 0.088 0.533 0.000933 1140 -0.45 803 1 0 0.638 0.178 2.47 PRS_PLINK_1e.06 TRUE 571.81 Portal hypertension Both 1 8 10 digestive chartreuse4 8, 1 2, 0 2, 0 2, 1 2, 0 0.00182 21 1 0 1 0.116 1.03 -0.128 1580 1 0 0.879 0.245 1.59 PRS_PLINK_1e.06 TRUE 572 Ascites (non malignant) Both 1 23 10 digestive chartreuse4 23, 1 6, 0 6, 0 5, 0 6, 1 0.311 0.581 0.593 0.227 1.36 0.511 33.4 0.765 1.69 0.651 0.186 2.15 0.196 709 PRS_PLINK_1e.06 TRUE 573 Other disorders of liver Both 7 38 10 digestive chartreuse4 38, 7 9, 3 9, 0 9, 4 10, 0 -0.199 0.416 0.632 0.199 0.819 0.348 1.78 -2.83 2.59 0.273 0.563 0.0588 9.92e-07 3.63 -0.393 1.23 0.75 0.125 0.675 0.0636 5.1 -1.77 1.69 0.297 0.527 0.171 2.19e-07 3.18 PRS_PLINK_1e.06 TRUE 573.1 Chronic passive congestion of liver Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 573.2 Liver replaced by transplant Both 0 6 10 digestive chartreuse4 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 573.3 Hepatomegaly Both 1 5 10 digestive chartreuse4 5, 1 2, 1 1, 0 1, 0 1, 0 -0.211 716 1 0 0.81 0.106 3.7 0.156 3480 1 0 1.17 0.806 5.03 4.41e-05 66.5 1 0 1 0.631 1.12 0.014 49.8 1 0 1.01 0.668 1.34 PRS_PLINK_1e.06 TRUE 573.4 Acute and subacute necrosis of liver Both 0 3 10 digestive chartreuse4 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 573.5 Jaundice (not of newborn) Both 2 13 10 digestive chartreuse4 13, 2 4, 0 3, 1 3, 1 3, 0 -0.46 1.38 0.74 0.131 0.631 0.0327 7.32 -0.0968 321 1 0 0.908 0.892 1.04 0.214 581 1 0 1.24 2.77e-05 1280 PRS_PLINK_1e.06 TRUE 573.6 Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH] Both 7 31 10 digestive chartreuse4 31, 7 7, 0 8, 1 7, 5 8, 1 0.196 0.446 0.66 0.181 1.22 0.524 3.08 0.506 2.65 0.848 0.071 1.66 0.0324 31100 2.61 2.05 0.203 0.693 13.6 0.734 1.29e+09 0.135 1.94 0.945 0.025 1.14 0.00649 55.5 PRS_PLINK_1e.06 TRUE 573.7 Abnormal results of function study of liver Both 7 30 10 digestive chartreuse4 30, 7 7, 2 7, 0 7, 5 8, 0 -0.0914 0.436 0.834 0.079 0.913 0.394 2.05 -3.2 3.52 0.363 0.44 0.0409 3.65e-05 12.1 -0.254 1.77 0.886 0.053 0.775 0.0446 17.8 -2.08 1.97 0.289 0.538 0.125 2.18e-05 2.53 PRS_PLINK_1e.06 TRUE 573.9 Abnormal serum enzyme levels Both 13 39 10 digestive chartreuse4 39, 13 9, 0 10, 4 9, 6 10, 3 0.525 0.393 0.181 0.743 1.69 0.861 3.78 1.82 1.9 0.339 0.469 6.15 0.274 4.06e+08 2.43 1.48 0.101 0.995 11.4 1.02 344 1.03 1.59 0.514 0.289 2.81 0.156 145 PRS_PLINK_1e.06 TRUE 574 Cholelithiasis and cholecystitis Both 1 45 10 digestive chartreuse4 45, 1 11, 0 11, 1 11, 0 11, 0 -0.164 0.576 0.776 0.11 0.849 0.247 5.48 0.197 1.36 0.885 0.053 1.22 0.0628 31.4 PRS_PLINK_1e.06 TRUE 574.1 Cholelithiasis Both 1 43 10 digestive chartreuse4 43, 1 10, 0 11, 1 10, 0 11, 0 -0.124 0.57 0.828 0.082 0.884 0.262 4.94 0.299 1.43 0.834 0.079 1.35 0.0852 38.4 PRS_PLINK_1e.06 TRUE 574.11 Cholelithiasis with acute cholecystitis Both 0 6 10 digestive chartreuse4 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 574.12 Cholelithiasis with other cholecystitis Both 0 14 10 digestive chartreuse4 14, 0 4 3 3 4 PRS_PLINK_1e.06 TRUE 574.2 Calculus of bile duct Both 0 11 10 digestive chartreuse4 11, 0 3 3 2 3 PRS_PLINK_1e.06 TRUE 574.3 Cholecystitis without cholelithiasis Both 0 14 10 digestive chartreuse4 14, 0 4 3 3 4 PRS_PLINK_1e.06 TRUE 575 Other biliary tract disease Both 0 33 10 digestive chartreuse4 33, 0 8 8 8 8 PRS_PLINK_1e.06 TRUE 575.1 Cholangitis Both 0 1 10 digestive chartreuse4 1, 0 PRS_PLINK_1e.06 TRUE 575.2 Obstruction of bile duct Both 0 5 10 digestive chartreuse4 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 575.6 Cholesterolosis of gallbladder Both 0 5 10 digestive chartreuse4 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 575.7 Other disorders of gallbladder Both 0 12 10 digestive chartreuse4 12, 0 2 3 3 3 PRS_PLINK_1e.06 TRUE 575.8 Other disorders of biliary tract Both 0 12 10 digestive chartreuse4 12, 0 3 3 3 3 PRS_PLINK_1e.06 TRUE 577 Diseases of pancreas Both 3 31 10 digestive chartreuse4 31, 3 8, 0 8, 0 7, 1 8, 2 0.782 0.94 0.406 0.392 2.19 0.157 53.8 0.356 2.38 0.881 0.055 1.43 0.00882 1920 1.21 1.93 0.531 0.275 3.35 0.162 326000 PRS_PLINK_1e.06 TRUE 577.1 Acute pancreatitis Both 1 19 10 digestive chartreuse4 19, 1 5, 0 5, 0 4, 0 5, 1 0.626 0.884 0.478 0.32 1.87 0.436 19.3 1.15 87.9 0.99 0.005 3.17 2.95 3.4 PRS_PLINK_1e.06 TRUE 577.2 Chronic pancreatitis Both 0 3 10 digestive chartreuse4 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 577.3 Cyst and pseudocyst of pancreas Both 0 4 10 digestive chartreuse4 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 578 Gastrointestinal hemorrhage Both 13 46 10 digestive chartreuse4 46, 13 11, 1 11, 6 11, 4 12, 2 0.193 0.339 0.57 0.244 1.21 0.658 2.44 3.2 2.26 0.156 0.806 24.5 0.656 37200 1.81 1.48 0.222 0.653 6.11 0.542 373 0.158 1.29 0.903 0.044 1.17 0.0028 27.5 PRS_PLINK_1e.06 TRUE 578.1 Hematemesis Both 4 5 10 digestive chartreuse4 5, 4 2, 1 1, 0 1, 3 1, 0 -0.123 96.5 0.999 0 0.884 0.205 0.977 0.000182 35.9 1 0 1 0.923 1.05 0.0183 241 1 0 1.02 0.743 1.79 0.0467 54.2 0.999 0 1.05 0.851 1.14 PRS_PLINK_1e.06 TRUE 578.2 Blood in stool Both 7 33 10 digestive chartreuse4 33, 7 8, 1 8, 1 8, 2 8, 3 0.693 0.598 0.246 0.608 2 0.714 9.74 -0.546 2.19 0.803 0.095 0.579 0.00715 258000 1.38 1.92 0.473 0.325 3.97 0.171 2620 1.46 1.6 0.36 0.444 4.31 0.391 4330 PRS_PLINK_1e.06 TRUE 578.8 Hemorrhage of rectum and anus Both 7 31 10 digestive chartreuse4 31, 7 7, 0 8, 2 7, 3 8, 2 0.518 0.567 0.361 0.443 1.68 0.62 7.82 0.0644 1.95 0.974 0.012 1.07 0.036 174 0.399 2.36 0.865 0.063 1.49 0.0346 3820 1.33 1.61 0.409 0.388 3.78 0.216 715 PRS_PLINK_1e.06 TRUE 578.9 Hemorrhage of gastrointestinal tract Both 3 16 10 digestive chartreuse4 16, 3 4, 0 4, 1 4, 2 4, 0 -0.0395 1.15 0.973 0.012 0.961 0.000163 14.3 0.062 1020 1 0 1.06 0.673 1.77 3.5 11600000 1 0 33.1 2.65e-05 2590 PRS_PLINK_1e.06 TRUE 579 Other symptoms involving abdomen and pelvis Both 6 41 10 digestive chartreuse4 41, 6 10, 1 10, 0 10, 1 10, 4 0.634 0.482 0.188 0.725 1.89 0.805 8.83 -0.481 1.81 0.79 0.102 0.618 0.000123 77.3 0.536 1.36 0.694 0.159 1.71 0.163 21800 1.64 1.29 0.205 0.689 5.14 0.565 38600 PRS_PLINK_1e.06 TRUE 579.2 Splenomegaly Both 1 9 10 digestive chartreuse4 9, 1 3, 0 2, 1 2, 0 2, 0 -0.0138 1.61 0.993 0.003 0.986 0.0833 11.2 0.0109 531 1 0 1.01 0.776 2.8 PRS_PLINK_1e.06 TRUE 579.8 Nonspecific abnormal findings in stool contents Both 2 19 10 digestive chartreuse4 19, 2 5, 0 5, 2 4, 0 5, 0 -0.00857 0.938 0.993 0.003 0.991 0.032 9.78 0.112 3.56 0.975 0.011 1.12 0.000362 16700 PRS_PLINK_1e.06 TRUE 580 Nephritis; nephrosis; renal sclerosis Both 15 11 11 genitourinary black 11, 15 3, 6 3, 1 2, 1 3, 7 0.268 0.717 0.709 0.15 1.31 0.359 5.3 -0.787 1.98 0.691 0.16 0.455 0.00234 25.5 -4.85 18.7 0.795 0.1 0.00781 0.00585 0.0102 0.305 1.67 0.855 0.068 1.36 0.0817 28.7 PRS_PLINK_1e.06 TRUE 580.1 Glomerulonephritis Both 2 4 11 genitourinary black 4, 2 1, 0 1, 0 1, 1 1, 1 -0.0523 566 1 0 0.949 0.591 1.41 -0.00976 25.4 1 0 0.99 0.93 1.05 -0.182 3660 1 0 0.833 0.184 1.64 PRS_PLINK_1e.06 TRUE 580.11 Proliferative glomerulonephritis Both 1 1 11 genitourinary black 1, 1 -0.000525 52.7 1 0 0.999 0.988 1.01 PRS_PLINK_1e.06 TRUE 580.12 Non-proliferative glomerulonephritis Both 0 1 11 genitourinary black 1, 0 PRS_PLINK_1e.06 TRUE 580.13 Acute glomerulonephritis, NOS Both 1 1 11 genitourinary black 1, 1 12.5 4.91e+11 1 0 268000 4.23e-94 2.67e+77 PRS_PLINK_1e.06 TRUE 580.14 Chronic glomerulonephritis, NOS Both 0 2 11 genitourinary black 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 580.2 Nephrotic syndrome without mention of glomerulonephritis Both 0 3 11 genitourinary black 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 580.3 Nephritis and nephropathy without mention of glomerulonephritis Both 13 11 11 genitourinary black 11, 13 3, 6 3, 1 2, 1 3, 5 0.0631 0.781 0.936 0.029 1.07 0.216 4.7 -0.787 1.98 0.691 0.16 0.455 0.00234 25.5 -4.85 18.7 0.795 0.1 0.00781 0.00585 0.0102 0.463 1.71 0.786 0.105 1.59 0.0908 37 PRS_PLINK_1e.06 TRUE 580.31 Nephritis and nephropathy in diseases classified elsewhere Both 11 9 11 genitourinary black 9, 11 3, 5 2, 1 2, 1 2, 4 -0.115 0.892 0.898 0.047 0.891 0.0759 4.4 -6.97 411 0.986 0.006 0.000936 0.000605 0.00145 2.3 96.4 0.981 0.008 9.96 8.58 11.5 -0.59 4.21 0.889 0.051 0.555 0.531 0.59 PRS_PLINK_1e.06 TRUE 580.32 Nephritis and nephropathy with pathological lesion Both 3 7 11 genitourinary black 7, 3 2, 1 2, 0 1, 1 2, 1 -1.85 6.71 0.783 0.106 0.157 5.87e-05 120 -2.72 1530 0.999 0.001 0.0657 1.91e-05 1140 1.14 1.2e+08 1 0 3.14 0.000838 24500 0.104 2300 1 0 1.11 0.4 3.42 PRS_PLINK_1e.06 TRUE 580.4 Renal sclerosis, NOS Both 1 3 11 genitourinary black 3, 1 1, 0 1, 0 0, 1 1, 0 0.885 3880 1 0 2.42 0.182 7.6 -0.011 280 1 0 0.989 0.843 1.15 PRS_PLINK_1e.06 TRUE 585 Renal failure Both 24 16 11 genitourinary black 16, 24 4, 9 4, 3 4, 4 4, 7 0.173 0.472 0.715 0.146 1.19 0.472 3.02 -1.26 1.59 0.428 0.369 0.284 1.65e-05 3.79 -0.372 1.43 0.795 0.1 0.69 0.0504 9.57 0.176 1.25 0.888 0.052 1.19 0.12 14.3 PRS_PLINK_1e.06 TRUE 585.1 Acute renal failure Both 8 14 11 genitourinary black 14, 8 4, 2 3, 1 3, 1 4, 4 0.0528 0.72 0.942 0.026 1.05 0.297 4.46 -0.59 3.69 0.873 0.059 0.554 0.542 0.562 5.52 28.9 0.848 0.071 250 3.54e-13 434 1.07 1.97 0.586 0.232 2.92 0.117 68.4 PRS_PLINK_1e.06 TRUE 585.2 Renal failure NOS Both 4 6 11 genitourinary black 6, 4 2, 2 1, 0 1, 1 2, 1 -0.757 24.1 0.975 0.011 0.469 0.446 0.494 0.741 11900 1 0 2.1 4.95e-12 3.8e+08 0.133 1520 1 0 1.14 0.803 1.26 -0.487 3190 1 0 0.614 0.014 9.83 PRS_PLINK_1e.06 TRUE 585.3 Chronic renal failure [CKD] Both 17 15 11 genitourinary black 15, 17 4, 6 4, 5 3, 0 4, 5 -0.064 0.654 0.922 0.035 0.938 0.246 3.77 -0.836 3.26 0.798 0.098 0.433 9.47e-06 922 -0.00127 404 1 0 0.999 0.846 1.53 -0.119 1.67 0.943 0.025 0.888 0.0341 346 PRS_PLINK_1e.06 TRUE 585.31 Renal dialysis Both 0 5 11 genitourinary black 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 585.32 End stage renal disease Both 1 9 11 genitourinary black 9, 1 3, 0 2, 0 2, 0 2, 1 -0.269 2.01 0.894 0.049 0.764 0.0166 32.8 -0.312 44900000 1 0 0.732 0.00644 71.9 PRS_PLINK_1e.06 TRUE 585.33 Chronic Kidney Disease, Stage III Both 7 11 11 genitourinary black 11, 7 3, 2 3, 3 2, 2 3, 0 0.207 0.897 0.817 0.088 1.23 0.262 14.1 -1.92 6.07 0.752 0.124 0.147 1.24e-05 929 -0.147 57 0.998 0.001 0.863 0.0437 19.7 -0.0252 358 1 0 0.975 0.626 2.38 PRS_PLINK_1e.06 TRUE 585.34 Chronic Kidney Disease, Stage IV Both 0 10 11 genitourinary black 10, 0 3 2 2 3 PRS_PLINK_1e.06 TRUE 585.4 Chronic kidney disease, Stage I or II Both 10 10 11 genitourinary black 10, 10 3, 5 2, 3 2, 0 3, 2 0.532 1.18 0.651 0.186 1.7 0.17 32.5 -0.755 3.18 0.812 0.09 0.47 0.00241 96.2 0.396 2190000 1 0 1.49 0.0522 12.6 -0.852 4.94 0.863 0.064 0.427 0.0024 98.5 PRS_PLINK_1e.06 TRUE 586 Other disorders of the kidney and ureters Both 37 17 11 genitourinary black 17, 37 5, 12 4, 4 4, 5 4, 16 0.554 0.405 0.171 0.766 1.74 0.846 4.03 -0.619 1.34 0.643 0.192 0.539 0.0295 5.98 -0.0415 1.22 0.973 0.012 0.959 0.109 8.5 0.53 0.922 0.566 0.247 1.7 0.302 10.9 PRS_PLINK_1e.06 TRUE 586.1 Anatomical abnormatilies of kidney and ureters Both 2 2 11 genitourinary black 2, 2 1, 1 1, 1 1, 1 1, 1 0.234 5500 1 0 1.26 0.0151 2580 -0.698 1530 1 0 0.497 0.00523 35.7 PRS_PLINK_1e.06 TRUE 586.11 Small kidney Both 1 0 11 genitourinary black 0, 1 PRS_PLINK_1e.06 TRUE 586.12 Vesicoureteral reflux Both 2 1 11 genitourinary black 1, 2 0.156 14600 1 0 1.17 0.079 241 PRS_PLINK_1e.06 TRUE 586.2 Cyst of kidney, acquired Both 2 6 11 genitourinary black 6, 2 2, 1 1, 1 1, 0 2, 0 -1.02 277 0.997 0.001 0.359 0.0308 2.29 -0.0264 1480 1 0 0.974 0.57 1.29 -1.63 15400 1 0 0.197 0.178 5.94 -0.126 2510 1 0 0.882 0.277 1.49 PRS_PLINK_1e.06 TRUE 586.3 Vascular disorders of kidney/hypertrophy Both 0 1 11 genitourinary black 1, 0 PRS_PLINK_1e.06 TRUE 586.4 Stricture/obstruction of ureter Both 3 6 11 genitourinary black 6, 3 2, 2 1, 0 1, 0 2, 1 -0.739 11.9 0.95 0.022 0.478 0.15 1.5 0.533 27900 1 0 1.7 0.169 157 0.328 12900 1 0 1.39 0.367 10.4 0.337 4760 1 0 1.4 0.121 16.9 PRS_PLINK_1e.06 TRUE 587 Kidney replaced by transpant Both 1 8 11 genitourinary black 8, 1 2, 0 2, 0 2, 0 2, 1 -0.0949 41.4 0.998 0.001 0.909 0.231 3.53 -0.0283 3790 1 0 0.972 0.374 2.96 PRS_PLINK_1e.06 TRUE 588 Disorders resulting from impaired renal function Both 2 10 11 genitourinary black 10, 2 3, 1 2, 0 2, 0 3, 1 0.363 2.6 0.889 0.051 1.44 1.39 1.48 -0.0139 37.6 1 0 0.986 0.855 1.05 0.0697 1130 1 0 1.07 0.364 1.82 -0.0436 54.6 0.999 0 0.957 0.437 1.33 PRS_PLINK_1e.06 TRUE 588.1 Renal osteodystrophy Both 0 5 11 genitourinary black 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 588.2 Secondary hyperparathyroidism (of renal origin) Both 2 8 11 genitourinary black 8, 2 2, 1 2, 0 2, 0 2, 1 0.126 3.99 0.975 0.011 1.13 1.12 1.15 0.0142 15.8 0.999 0 1.01 0.868 1.18 0.158 3470 1 0 1.17 0.58 1.3 0.101 1730 1 0 1.11 0.217 1.85 PRS_PLINK_1e.06 TRUE 589 Abnormal results of function study of kidney Both 5 8 11 genitourinary black 8, 5 2, 2 2, 2 2, 1 2, 0 0.841 2.02 0.678 0.169 2.32 0.187 19 0.0112 420 1 0 1.01 0.843 1.17 0.0913 4890 1 0 1.1 0.593 1.31 0.236 6790 1 0 1.27 0.896 1.44 PRS_PLINK_1e.06 TRUE 590 Pyelonephritis Both 4 8 11 genitourinary black 8, 4 2, 1 2, 0 2, 2 2, 1 1.49 5.43 0.784 0.105 4.42 0.00163 215000 0.153 25600 1 0 1.16 0.337 10.3 0.207 6160 1 0 1.23 0.112 1.77 13.1 23200 1 0 469000 1.99e-15 8.06e+25 PRS_PLINK_1e.06 TRUE 591 Urinary tract infection Both 25 31 11 genitourinary black 31, 25 8, 9 8, 2 7, 8 8, 5 -0.365 0.352 0.3 0.523 0.694 0.347 1.32 -2.33 1.6 0.145 0.837 0.0978 0.000315 2.09 -1.31 1.31 0.319 0.496 0.271 0.00821 2.58 -0.175 0.849 0.837 0.077 0.84 0.183 3.74 PRS_PLINK_1e.06 TRUE 592 Cystitis and urethritis Both 9 15 11 genitourinary black 15, 9 4, 4 4, 1 3, 2 4, 2 0.0317 0.843 0.97 0.013 1.03 0.216 4.86 -1.34 2.1 0.522 0.282 0.261 0.00548 7.96 2.28 4.55 0.617 0.21 9.74 8.26 11.4 2.37 2.51 0.343 0.465 10.7 0.252 4210 PRS_PLINK_1e.06 TRUE 592.1 Cystitis Both 9 14 11 genitourinary black 14, 9 4, 4 3, 1 3, 1 4, 3 0.202 0.901 0.823 0.085 1.22 0.236 6.49 -1.43 2.34 0.542 0.266 0.24 0.00476 6.6 -0.0565 3.4 0.987 0.006 0.945 0.00541 541 3.43 2.93 0.241 0.617 30.9 0.257 150000 PRS_PLINK_1e.06 TRUE 592.11 Acute cystitis Both 6 10 11 genitourinary black 10, 6 3, 3 2, 0 2, 0 3, 3 2.14 1.7 0.208 0.682 8.53 0.794 440 -0.82 4600000 1 0 0.44 0.00165 38.2 -0.00531 683 1 0 0.995 0.667 1.99 2.24 2.95 0.447 0.35 9.43 0.175 4410 PRS_PLINK_1e.06 TRUE 592.12 Chronic cystitis Both 2 3 11 genitourinary black 3, 2 1, 0 1, 0 1, 2 1, 0 -0.334 11200000 1 0 0.716 0.0205 13.9 -0.31 33200 1 0 0.733 0.0461 3.84 PRS_PLINK_1e.06 TRUE 592.13 Chronic interstitial cystitis Both 1 7 11 genitourinary black 7, 1 2, 0 2, 0 1, 0 2, 1 0.0179 457 1 0 1.02 0.868 1.27 0.159 3300 1 0 1.17 0.686 1.46 PRS_PLINK_1e.06 TRUE 592.2 Urethritis and urethral syndrome Both 2 1 11 genitourinary black 1, 2 0.148 15.1 0.992 0.003 1.16 0.507 1.31 PRS_PLINK_1e.06 TRUE 593 Hematuria Both 17 29 11 genitourinary black 29, 17 8, 8 7, 1 7, 3 7, 5 -0.597 0.389 0.125 0.903 0.551 0.243 1.07 -2.35 1.63 0.151 0.822 0.0955 0.00066 1.82 -1.95 1.39 0.163 0.789 0.143 0.00368 4.82 -0.709 1.01 0.483 0.316 0.492 0.0687 2.93 PRS_PLINK_1e.06 TRUE 593.1 Gross hematuria Both 6 16 11 genitourinary black 16, 6 4, 3 4, 0 4, 3 4, 0 -0.435 0.64 0.497 0.304 0.647 0.145 3.67 -0.107 1980 1 0 0.898 0.266 1.53 -0.628 1.74 0.718 0.144 0.534 0.00122 9.71 -1.37 3.38 0.686 0.164 0.255 0.000694 25.5 PRS_PLINK_1e.06 TRUE 593.2 Microscopic hematuria Both 6 9 11 genitourinary black 9, 6 3, 2 2, 0 2, 2 2, 2 0.778 1.63 0.634 0.198 2.18 0.0892 8420 0.023 1490 1 0 1.02 0.648 1.65 -0.0793 6190 1 0 0.924 0.195 3.91 0.164 7110000 1 0 1.18 0.0288 30.3 PRS_PLINK_1e.06 TRUE 594 Urinary calculus Both 13 43 11 genitourinary black 43, 13 10, 2 11, 2 10, 2 11, 7 0.551 0.45 0.221 0.656 1.74 0.787 5.16 -0.7 2.04 0.732 0.136 0.497 0.00186 23200 -1.02 1.6 0.522 0.282 0.36 4.16e-05 12.5 0.678 1.4 0.629 0.202 1.97 0.065 59.4 PRS_PLINK_1e.06 TRUE 594.1 Calculus of kidney Both 13 43 11 genitourinary black 43, 13 10, 2 11, 2 10, 2 11, 7 0.551 0.45 0.221 0.656 1.74 0.787 5.16 -0.7 2.04 0.732 0.136 0.497 0.00186 23200 -1.02 1.6 0.522 0.282 0.36 4.16e-05 12.5 0.678 1.4 0.629 0.202 1.97 0.065 59.4 PRS_PLINK_1e.06 TRUE 594.2 Calculus of lower urinary tract Both 1 4 11 genitourinary black 4, 1 1, 0 1, 1 1, 0 1, 0 0.0981 5220 1 0 1.1 0.00195 47200 -4.66 3.81e+08 1 0 0.00946 1e-09 4720000 PRS_PLINK_1e.06 TRUE 594.3 Calculus of ureter Both 2 17 11 genitourinary black 17, 2 5, 1 4, 0 4, 1 4, 0 -0.405 0.882 0.646 0.19 0.667 0.00709 4.63 3.27 8.54 0.702 0.154 26.2 21.1 32.5 -0.133 1.75 0.939 0.027 0.875 0.852 0.919 1.39 7.39 0.851 0.07 4 3.6 4.39 PRS_PLINK_1e.06 TRUE 594.8 Renal colic Both 1 5 11 genitourinary black 5, 1 2, 0 1, 0 1, 0 1, 1 -0.00539 85.2 1 0 0.995 0.568 2.07 7.56e-05 468 1 0 1 0.522 1.39 PRS_PLINK_1e.06 TRUE 595 Hydronephrosis Both 4 15 11 genitourinary black 15, 4 4, 0 4, 1 3, 1 4, 2 0.506 0.779 0.516 0.288 1.66 0.467 98.6 1.33 1.2e+07 1 0 3.78 4.29e-05 116000 0.404 311000 1 0 1.5 1.51 2.18 -1.4 3.62 0.698 0.156 0.246 0.218 66.8 PRS_PLINK_1e.06 TRUE 596 Other disorders of bladder Both 5 25 11 genitourinary black 25, 5 6, 0 6, 1 6, 3 6, 1 0.251 0.727 0.73 0.137 1.29 0.303 7.31 1.38 4.07 0.735 0.134 3.97 6.19e-05 22700 -3.79 7.31 0.604 0.219 0.0225 4.89e-15 3380 0.648 5.53 0.907 0.043 1.91 1.36e-07 6.8e+07 PRS_PLINK_1e.06 TRUE 596.1 Bladder neck obstruction Both 1 2 11 genitourinary black 2, 1 1, 0 1, 1 1, 0 1, 1 -0.636 12400 1 0 0.529 0.00167 5.48 -0.97 18100 1 0 0.379 8.04e-05 9.74 PRS_PLINK_1e.06 TRUE 596.5 Functional disorders of bladder Both 5 16 11 genitourinary black 16, 5 3, 0 4, 0 4, 2 4, 3 0.752 0.791 0.341 0.467 2.12 0.363 87.2 -0.184 827 1 0 0.832 0.808 1.63 -0.939 28 0.973 0.012 0.391 0.354 0.433 PRS_PLINK_1e.06 TRUE 597 Other disorders of urethra and urinary tract Both 3 7 11 genitourinary black 7, 3 2, 1 2, 0 1, 2 2, 0 -0.0496 1.78 0.978 0.01 0.952 0.073 14.5 -3.88 2.66e+08 1 0 0.0206 1.55e-11 7.69e+09 0.284 3730 1 0 1.33 0.293 1.75 0.397 4340 1 0 1.49 0.378 2.04 PRS_PLINK_1e.06 TRUE 597.1 Urethral stricture (not specified as infectious) Both 2 2 11 genitourinary black 2, 2 1, 2 1, 0 1, 2 1, 0 0.0762 2440 1 0 1.08 0.684 2.8 3.34 2810 0.999 0 28.1 0.00702 1510000 PRS_PLINK_1e.06 TRUE 597.2 Urinary complications NEC Both 1 8 11 genitourinary black 8, 1 1, 1 2, 0 2, 0 2, 0 -0.307 21.1 0.988 0.005 0.736 0.0191 21.3 0.0124 38.6 1 0 1.01 0.928 1.12 1.12 1190 0.999 0 3.05 0.0912 280 -0.0532 703 1 0 0.948 0.597 1.61 PRS_PLINK_1e.06 TRUE 597.8 Urethral hypermobility/ISD Both 0 2 11 genitourinary black 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 598 Abnormal findings on examination of urine Both 0 2 11 genitourinary black 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 598.4 Other cells and casts in urine Both 0 2 11 genitourinary black 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 599 Other symptoms/disorders or the urinary system Both 25 35 11 genitourinary black 35, 25 8, 11 9, 5 8, 5 9, 4 -0.313 0.318 0.325 0.488 0.731 0.402 1.31 -1.94 1.2 0.107 0.969 0.144 0.00507 1.23 -1.53 1.47 0.298 0.526 0.216 0.00524 4.07 -0.769 0.942 0.414 0.383 0.463 0.08 2.48 PRS_PLINK_1e.06 TRUE 599.1 Urinary obstruction Both 3 6 11 genitourinary black 6, 3 2, 1 1, 0 1, 1 2, 1 -0.292 10.2 0.977 0.01 0.747 0.475 0.97 -0.263 5710 1 0 0.769 0.12 2.15 0.00857 16.7 1 0 1.01 0.728 1.04 -0.418 4010 1 0 0.658 0.169 1.71 PRS_PLINK_1e.06 TRUE 599.2 Retention of urine Both 11 27 11 genitourinary black 27, 11 6, 5 7, 2 6, 2 7, 2 -0.234 0.408 0.566 0.247 0.791 0.349 1.62 -0.737 1.84 0.688 0.162 0.479 0.000284 140 -0.111 1.61 0.945 0.025 0.895 0.0443 217 -0.443 1.41 0.753 0.123 0.642 0.0361 14.3 PRS_PLINK_1e.06 TRUE 599.3 Dysuria Both 13 27 11 genitourinary black 27, 13 6, 6 7, 2 6, 3 7, 2 -0.452 0.391 0.247 0.607 0.636 0.304 1.25 -1.67 1.28 0.19 0.721 0.188 0.016 1.31 0.902 2.03 0.656 0.183 2.46 0.0589 25.6 -1.09 1.38 0.43 0.366 0.337 0.011 2.95 PRS_PLINK_1e.06 TRUE 599.4 Urinary incontinence Both 6 24 11 genitourinary black 24, 6 5, 2 6, 1 6, 2 6, 1 0.552 1.09 0.611 0.214 1.74 0.173 981 -0.017 44.1 1 0 0.983 0.805 1.74 -0.439 2.11 0.835 0.078 0.645 0.0147 75.8 1.29 2.19 0.556 0.255 3.63 0.12 297000 PRS_PLINK_1e.06 TRUE 599.5 Frequency of urination and polyuria Both 10 31 11 genitourinary black 31, 10 7, 4 8, 2 7, 3 8, 1 -0.486 0.469 0.3 0.524 0.615 0.246 1.54 -1.34 1.93 0.489 0.311 0.263 1.98e-05 960 -0.0236 1.4 0.987 0.006 0.977 0.015 31.9 -0.483 1.92 0.802 0.096 0.617 3.57e-07 1740 PRS_PLINK_1e.06 TRUE 599.6 Oliguria and anuria Both 1 10 11 genitourinary black 10, 1 3, 0 2, 0 2, 0 3, 1 1.9 6 0.752 0.124 6.66 5.55 7.79 0.0817 1210 1 0 1.09 0.529 2.43 PRS_PLINK_1e.06 TRUE 599.7 Urethral discharge Both 0 6 11 genitourinary black 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 599.8 Other symptoms involving urinary system Both 12 28 11 genitourinary black 28, 12 6, 5 7, 3 7, 2 7, 2 0.239 0.601 0.691 0.16 1.27 0.45 4.48 -0.324 1.73 0.851 0.07 0.723 0.0046 56.2 0.256 1.68 0.879 0.056 1.29 0.0628 74.6 0.277 1.93 0.886 0.053 1.32 0.0274 239 PRS_PLINK_1e.06 TRUE 599.9 Other abnormality of urination Both 5 21 11 genitourinary black 21, 5 5, 2 5, 1 5, 0 5, 2 -0.21 0.532 0.693 0.159 0.81 0.269 2.03 -0.28 2.95 0.924 0.034 0.756 0.000476 736 1.23 4.48 0.784 0.106 3.42 0.016 3.71 -0.032 2.05 0.988 0.005 0.968 0.0519 41.7 PRS_PLINK_1e.06 TRUE 600 Hyperplasia of prostate Male 3 16 11 genitourinary black 16, 3 4, 2 4, 0 4, 1 4, 0 -0.0632 1.03 0.951 0.022 0.939 0.00898 13.5 -2.01 3.63 0.581 0.236 0.135 0.000189 19.4 -0.897 2.41 0.71 0.149 0.408 0.00299 11.9 1.02 4.23 0.809 0.092 2.77 0.00358 53700 PRS_PLINK_1e.06 TRUE 601 Inflammatory diseases of prostate Male 3 13 11 genitourinary black 13, 3 4, 2 3, 0 3, 1 3, 0 -0.284 0.883 0.748 0.126 0.753 0.101 8.29 -0.836 106 0.994 0.003 0.433 6.82e-06 27400 -0.199 2.74 0.942 0.026 0.82 0.0154 57.7 0.798 7.18 0.912 0.04 2.22 0.281 2.3 PRS_PLINK_1e.06 TRUE 601.1 Prostatitis Male 3 5 11 genitourinary black 5, 3 2, 2 1, 1 1, 0 1, 0 0.113 73.1 0.999 0.001 1.12 0.299 3.85 -0.126 428 1 0 0.881 0.594 1.29 -0.0225 472 1 0 0.978 0.318 1.37 0.154 1880 1 0 1.17 0.358 1.38 PRS_PLINK_1e.06 TRUE 601.11 Acute prostatitis Male 1 1 11 genitourinary black 1, 1 -0.113 29.4 0.997 0.001 0.893 0.887 1.35 PRS_PLINK_1e.06 TRUE 601.12 Chronic prostatitis Male 0 1 11 genitourinary black 1, 0 PRS_PLINK_1e.06 TRUE 601.3 Orchitis and epididymitis Male 0 4 11 genitourinary black 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 601.4 Balanoposthitis Male 0 3 11 genitourinary black 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 602 Other disorders of prostate Male 1 3 11 genitourinary black 3, 1 1, 0 1, 1 1, 0 1, 0 0.166 6920 1 0 1.18 0.451 17.2 -0.459 6860 1 0 0.632 0.000705 5280 PRS_PLINK_1e.06 TRUE 602.3 Dysplasia of prostate Male 0 1 11 genitourinary black 1, 0 PRS_PLINK_1e.06 TRUE 603 Other disorders of testis Male 0 7 11 genitourinary black 7, 0 2 2 1 2 PRS_PLINK_1e.06 TRUE 603.1 Hydrocele Male 0 4 11 genitourinary black 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 603.2 Spermatocele Male 0 5 11 genitourinary black 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 604 Disorders of penis Male 2 6 11 genitourinary black 6, 2 2, 0 1, 0 1, 0 2, 2 0.143 26.7 0.996 0.002 1.15 3.83 3 1.94 5750 1 0 6.96 0.619 8.04 PRS_PLINK_1e.06 TRUE 604.3 Peyronie's disease Male 1 1 11 genitourinary black 1, 1 0.207 2350 1 0 1.23 0.0816 16.8 PRS_PLINK_1e.06 TRUE 605 Erectile dysfunction [ED] Male 12 11 11 genitourinary black 11, 12 3, 7 3, 2 2, 3 3, 0 -0.27 0.557 0.628 0.202 0.763 0.265 2.6 -0.00113 2.82 1 0 0.999 0.00407 107 -0.415 1.81 0.819 0.087 0.66 0.0102 13.5 -0.481 2.6 0.853 0.069 0.618 1.89e-05 177 PRS_PLINK_1e.06 TRUE 608 Other disorders of male genital organs Male 3 14 11 genitourinary black 14, 3 4, 2 3, 0 3, 1 4, 0 -0.403 0.57 0.479 0.319 0.668 0.159 1.74 -2.52 2.74 0.357 0.448 0.0801 0.000796 2.97 0.446 3.53 0.9 0.046 1.56 0.00839 583 -0.53 6.65 0.936 0.029 0.588 0.00387 74.9 PRS_PLINK_1e.06 TRUE 609 Male infertility and abnormal spermatozoa Male 2 5 11 genitourinary black 5, 2 2, 0 1, 0 1, 0 1, 2 -0.431 13600 1 0 0.65 0.00258 1860000 4.17 20300 1 0 64.4 0.000924 3.21e+08 PRS_PLINK_1e.06 TRUE 609.1 Infertility, male Male 2 5 11 genitourinary black 5, 2 2, 0 1, 0 1, 0 1, 2 -0.297 9780 1 0 0.743 0.721 6.84 16 68200000 1 0 8920000 9.2e-23 7.01e+39 PRS_PLINK_1e.06 TRUE 609.11 Azoospermia and oligospermia Male 1 1 11 genitourinary black 1, 1 -0.00603 88.8 1 0 0.994 0.809 2.7 PRS_PLINK_1e.06 TRUE 609.2 Abnormal spermatozoa Male 0 2 11 genitourinary black 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 610 Benign mammary dysplasias Female 4 14 11 genitourinary black 14, 4 3, 3 3, 0 3, 0 4, 1 -0.0531 1.12 0.962 0.017 0.948 0.146 8.86 2.47 10.7 0.817 0.088 11.9 4.15e-08 28500000 0.0626 76.6 0.999 0 1.06 2e-04 4340 -1.26 3.55 0.723 0.141 0.284 0.000311 58.4 PRS_PLINK_1e.06 TRUE 610.1 Cystic mastopathy Female 3 8 11 genitourinary black 8, 3 1, 0 2, 2 2, 0 2, 1 -0.42 2.33 0.857 0.067 0.657 0.003 38 0.0439 5410 1 0 1.04 0.218 5.57 0.094 528 1 0 1.1 0.665 3.53 PRS_PLINK_1e.06 TRUE 610.2 Fibroadenosis of breast Female 0 1 11 genitourinary black 1, 0 PRS_PLINK_1e.06 TRUE 610.4 Benign neoplasm of breast Female 2 14 11 genitourinary black 14, 2 3, 1 3, 0 3, 0 4, 1 0.708 1.09 0.516 0.288 2.03 0.367 23.5 3.66 231 0.987 0.006 38.7 0.000718 4400000 0.376 5210 1 0 1.46 0.492 6.98 6.87 10.6 0.515 0.288 964 0.00069 1450 PRS_PLINK_1e.06 TRUE 610.8 Other specified benign mammary dysplasias Female 2 7 11 genitourinary black 7, 2 1, 0 2, 1 1, 0 2, 1 -2.69 13.6 0.842 0.074 0.0676 0.0566 0.0812 0.332 6400 1 0 1.39 0.000234 919 -3.62 5270 0.999 0 0.0267 1.47e-14 3.71e+10 PRS_PLINK_1e.06 TRUE 611 Abnormal findings on mammogram or breast exam Both 10 17 11 genitourinary black 17, 10 4, 5 4, 3 4, 1 4, 1 -0.312 0.773 0.686 0.164 0.732 0.136 4.43 0.00659 1.89 0.997 0.001 1.01 0.00323 1620 -2.77 3.34 0.407 0.391 0.0627 0.000126 16.1 1.99 4.03 0.622 0.206 7.29 0.00672 88600 PRS_PLINK_1e.06 TRUE 611.1 Abnormal mammogram Both 8 14 11 genitourinary black 14, 8 3, 5 3, 2 3, 1 4, 0 -0.23 0.846 0.786 0.105 0.795 0.146 5.84 -0.00917 2.07 0.996 0.002 0.991 0.0255 54 -2.91 3.46 0.401 0.397 0.0547 0.000111 12.2 -1.16 3.91 0.768 0.115 0.315 0.000459 34300 PRS_PLINK_1e.06 TRUE 611.11 Mammographic microcalcification Both 2 6 11 genitourinary black 6, 2 1, 0 1, 1 1, 1 2, 0 0.816 97.3 0.993 0.003 2.26 1.98 3.09 0.0611 1570 1 0 1.06 0.934 1.44 0.119 7730 1 0 1.13 5.66e-07 7060000 PRS_PLINK_1e.06 TRUE 611.3 Lump or mass in breast Both 5 16 11 genitourinary black 16, 5 3, 3 4, 1 4, 0 4, 1 1.12 1.1 0.309 0.51 3.07 0.165 41.6 0.773 2730 1 0 2.17 0.343 2.28 1.12 8.12 0.89 0.05 3.06 0.00233 2640 0.319 12.9 0.98 0.009 1.38 2.58e-10 2.04e+09 PRS_PLINK_1e.06 TRUE 612 Breast conditions, congenital or relating to hormones Both 2 11 11 genitourinary black 11, 2 2, 0 3, 1 2, 0 3, 1 -0.524 2.41 0.828 0.082 0.592 3.09e-05 17.2 -5.5e-05 3130 1 0 1 0.416 2.37 0.0067 1580 1 0 1.01 0.799 1.35 PRS_PLINK_1e.06 TRUE 612.1 Galactorrhea Both 0 1 11 genitourinary black 1, 0 PRS_PLINK_1e.06 TRUE 612.2 Hypertrophy of breast (Gynecomastia) Both 2 6 11 genitourinary black 6, 2 1, 0 1, 0 1, 1 2, 1 -0.0586 225 1 0 0.943 0.563 1.3 -0.0253 280 1 0 0.975 0.879 1.06 -0.000261 11600 1 0 1 0.124 5.74 PRS_PLINK_1e.06 TRUE 613 Other nonmalignant breast conditions Both 9 25 11 genitourinary black 25, 9 6, 3 6, 2 6, 2 6, 2 -0.0322 0.562 0.954 0.02 0.968 0.342 3.05 -0.284 1.4 0.84 0.076 0.753 0.0641 7.63 -0.062 1.49 0.967 0.015 0.94 0.0751 83 2.74 2.54 0.281 0.551 15.5 0.429 116000 PRS_PLINK_1e.06 TRUE 613.1 Inflammatory disease of breast Both 1 4 11 genitourinary black 4, 1 1, 0 1, 0 1, 0 1, 1 0.0497 7910 1 0 1.05 0.0727 22 -10.9 11800 0.999 0 1.94e-05 1.03e-14 7.74e+09 PRS_PLINK_1e.06 TRUE 613.5 Mastodynia Both 3 14 11 genitourinary black 14, 3 4, 0 3, 0 3, 1 4, 2 1.2 2.23 0.592 0.228 3.31 0.0751 578 0.476 5070 1 0 1.61 0.000979 137 0.97 16 0.952 0.021 2.64 3.65 19.2 PRS_PLINK_1e.06 TRUE 613.7 Other signs and symptoms in breast Both 4 7 11 genitourinary black 7, 4 2, 0 2, 2 1, 1 2, 1 -0.421 1.43 0.769 0.114 0.657 0.614 0.733 0.536 9640 1 0 1.71 0.0433 2.46 -0.168 1090 1 0 0.846 0.379 1.15 -0.0345 970 1 0 0.966 1.33e-06 29700 PRS_PLINK_1e.06 TRUE 613.8 Other specified disorders of breast Both 0 7 11 genitourinary black 7, 0 2 2 1 2 PRS_PLINK_1e.06 TRUE 613.9 Breast disorder NOS Both 2 10 11 genitourinary black 10, 2 3, 1 2, 1 2, 0 3, 0 -0.393 2.25 0.862 0.065 0.675 0.0201 18.2 -2.62 1780 0.999 0.001 0.0728 1.07e-06 30200 0.184 3140 1 0 1.2 0.594 1.27 -1.16 782 0.999 0.001 0.314 0.0113 0.235 PRS_PLINK_1e.06 TRUE 614 Inflammatory diseases of female pelvic organs Female 7 23 11 genitourinary black 23, 7 5, 1 6, 2 5, 3 6, 1 0.173 0.637 0.786 0.104 1.19 0.415 4.52 0.827 2.13 0.697 0.157 2.29 0.0889 1290 1.54 4.8 0.748 0.126 4.67 0.000348 326000 -1.03 3.85 0.789 0.103 0.357 6.6e-07 282 PRS_PLINK_1e.06 TRUE 614.1 Pelvic peritoneal adhesions, female (postoperative) (postinfection) Female 1 4 11 genitourinary black 4, 1 1, 0 1, 1 1, 0 1, 0 0.0132 376000 1 0 1.01 0.506 2.71 PRS_PLINK_1e.06 TRUE 614.3 Pelvic inflammatory disease (PID) Female 2 4 11 genitourinary black 4, 2 1, 1 1, 0 1, 1 1, 0 3.07 50100000 1 0 21.5 1.22e-27 2.25e+26 -0.0472 558 1 0 0.954 0.686 1.11 8.23 8420 0.999 0 3750 1.06e-14 1.24e+15 -0.296 3920 1 0 0.744 0.0752 1.92 PRS_PLINK_1e.06 TRUE 614.31 Acute inflammatory pelvic disease Female 0 1 11 genitourinary black 1, 0 PRS_PLINK_1e.06 TRUE 614.32 Chronic inflammatory pelvic disease Female 1 2 11 genitourinary black 2, 1 1, 1 1, 1 1, 1 1, 1 0.0223 200 1 0 1.02 0.745 1.79 PRS_PLINK_1e.06 TRUE 614.33 Pelvic inflammatory disease, NOS Female 1 4 11 genitourinary black 4, 1 1, 1 1, 0 1, 0 1, 1 3.31 3.56e+08 1 0 27.5 7.23e-13 3.14e+14 PRS_PLINK_1e.06 TRUE 614.4 Inflammatory diseases of uterus, except cervix Female 0 3 11 genitourinary black 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 614.5 Inflammatory disease of cervix, vagina, and vulva Female 5 23 11 genitourinary black 23, 5 5, 1 6, 1 5, 2 6, 1 -0.00535 0.687 0.994 0.003 0.995 0.316 3.71 0.416 2.45 0.865 0.063 1.52 0.028 1040 0.501 5.59 0.929 0.032 1.65 1.09e-06 335000 -1.03 3.85 0.789 0.103 0.357 6.6e-07 282 PRS_PLINK_1e.06 TRUE 614.51 Cervicitis and endocervicitis Female 0 4 11 genitourinary black 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 614.52 Vaginitis and vulvovaginitis Female 2 23 11 genitourinary black 23, 2 5, 1 6, 0 5, 1 6, 0 -0.803 0.885 0.364 0.439 0.448 0.0359 11.7 -0.77 2.65 0.771 0.113 0.463 0.00141 147 0.496 5.38 0.927 0.033 1.64 2.82e-06 66700 0.929 5.55 0.867 0.062 2.53 5.5e-05 36700 PRS_PLINK_1e.06 TRUE 614.53 Cyst or abscess of Bartholin's gland Female 2 2 11 genitourinary black 2, 2 1, 0 0, 2 1, 0 1, 0 0.136 26400000 1 0 1.15 0.133 27.3 -0.0355 2770 1 0 0.965 0.513 1.76 PRS_PLINK_1e.06 TRUE 614.54 Abscess or ulceration of vulva Female 1 1 11 genitourinary black 1, 1 0.004 2100 1 0 1 0.932 1.08 PRS_PLINK_1e.06 TRUE 615 Endometriosis Female 2 18 11 genitourinary black 18, 2 4, 0 4, 0 4, 2 5, 0 0.658 0.919 0.474 0.324 1.93 0.16 391 -2.89 10.6 0.785 0.105 0.0554 4.3e-10 1420000 PRS_PLINK_1e.06 TRUE 618 Genital prolapse Female 3 19 11 genitourinary black 19, 3 4, 1 5, 0 4, 0 5, 2 0.142 0.749 0.849 0.071 1.15 0.0783 9.55 -2.66 5.3 0.615 0.211 0.0697 6.24e-06 69.5 6.47 33.5 0.847 0.072 645 456 927 -1.83 5.5 0.74 0.131 0.161 0.113 0.267 PRS_PLINK_1e.06 TRUE 618.1 Prolapse of vaginal walls Female 1 11 11 genitourinary black 11, 1 2, 0 3, 0 2, 0 3, 1 0.00432 1.47 0.998 0.001 1 0.0645 85.4 -0.191 1500 1 0 0.826 0.285 1.96 PRS_PLINK_1e.06 TRUE 618.2 Uterine/Uterovaginal prolapse Female 0 6 11 genitourinary black 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 618.5 Prolapse of vaginal vault after hysterectomy Female 0 3 11 genitourinary black 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 618.6 Vaginal enterocele, congenital or acquired Female 2 7 11 genitourinary black 7, 2 1, 1 2, 0 1, 0 2, 1 -2.21 26.9 0.934 0.029 0.109 0.0957 0.125 -0.0129 794 1 0 0.987 0.55 1.22 -0.183 11700 1 0 0.832 0.0331 7.02 0.363 9610 1 0 1.44 0.144 3650 PRS_PLINK_1e.06 TRUE 619 Noninflammatory female genital disorders Female 12 19 11 genitourinary black 19, 12 4, 4 5, 2 4, 1 5, 5 -0.356 0.573 0.535 0.272 0.701 0.215 1.94 -1.5 1.73 0.385 0.414 0.223 0.00578 2.72 -2.3 3.05 0.45 0.347 0.1 7.14e-05 9.02 -0.00873 1.55 0.996 0.002 0.991 0.0729 12.2 PRS_PLINK_1e.06 TRUE 619.1 Noninflammatory disorders of ovary, fallopian tube, and broad ligament Female 2 12 11 genitourinary black 12, 2 3, 0 3, 0 3, 1 3, 1 -0.422 1.92 0.826 0.083 0.656 0.0168 2520 0.339 17.1 0.984 0.007 1.4 0.599 3.3 0.271 318 0.999 0 1.31 0.278 6.81 PRS_PLINK_1e.06 TRUE 619.2 Disorders of uterus, NEC Female 1 6 11 genitourinary black 6, 1 2, 0 1, 0 1, 0 2, 1 -0.0469 1410 1 0 0.954 0.186 3.15 -0.971 5490 1 0 0.379 0.00265 41.8 PRS_PLINK_1e.06 TRUE 619.3 Noninflammatory disorders of cervix Female 0 5 11 genitourinary black 5, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 619.4 Noninflammatory disorders of vagina Female 9 18 11 genitourinary black 18, 9 4, 4 4, 1 4, 1 5, 3 -0.935 0.729 0.2 0.699 0.393 0.0964 1.48 -2.09 2.21 0.344 0.463 0.123 0.000293 4.54 -1.67 2.87 0.56 0.252 0.188 0.00171 13.3 -0.985 1.86 0.596 0.225 0.373 0.0174 6.91 PRS_PLINK_1e.06 TRUE 619.5 Noninflammatory disorders of vulva and perineum Female 2 12 11 genitourinary black 12, 2 3, 0 3, 1 3, 0 3, 1 -0.393 2.87 0.891 0.05 0.675 0.00025 42.4 0.821 11800000 1 0 2.27 0.744 8.41 -0.419 699 1 0 0.658 0.00229 6.28 PRS_PLINK_1e.06 TRUE 620 Dysplasia of female genital organs Female 0 6 11 genitourinary black 6, 0 1 1 1 2 PRS_PLINK_1e.06 TRUE 620.1 Dysplasia of cervix Female 0 3 11 genitourinary black 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 621 Endometrial hyperplasia Female 0 6 11 genitourinary black 6, 0 1 1 1 2 PRS_PLINK_1e.06 TRUE 622 Polyp of female genital organs Female 3 20 11 genitourinary black 20, 3 4, 0 5, 1 5, 0 5, 2 -0.405 0.958 0.673 0.172 0.667 0.0136 9.88 2.17e-13 5.86 1 0 1 8.54e-05 10500 -5.61 16.2 0.73 0.137 0.00365 1.28e-20 2.45e+09 PRS_PLINK_1e.06 TRUE 622.1 Polyp of corpus uteri Female 2 14 11 genitourinary black 14, 2 3, 0 3, 1 3, 0 4, 1 -0.218 0.9 0.808 0.092 0.804 0.127 5.26 -1.47 5740 1 0 0.229 0.000537 61.9 -1.96 12100000 1 0 0.141 4.43e-11 4.83e+10 PRS_PLINK_1e.06 TRUE 622.2 Mucous polyp of cervix Female 1 7 11 genitourinary black 7, 1 2, 0 2, 0 1, 0 2, 1 -0.149 244 1 0 0.862 0.132 0.649 -0.113 3650 1 0 0.894 0.211 1.76 PRS_PLINK_1e.06 TRUE 623 Hypertrophy of female genital organs Female 0 13 11 genitourinary black 13, 0 4 3 3 3 PRS_PLINK_1e.06 TRUE 624 Symptoms involving female genital tract Female 4 17 11 genitourinary black 17, 4 4, 1 4, 0 4, 0 4, 3 0.752 1.23 0.54 0.268 2.12 0.249 140 -1.95 5.12 0.704 0.153 0.142 0.123 0.167 -2.44 6.27 0.697 0.157 0.0874 6.94e-07 917 -0.534 2.99 0.858 0.066 0.586 0.00371 66.6 PRS_PLINK_1e.06 TRUE 624.1 Dystrophy of female genital tract Female 1 1 11 genitourinary black 1, 1 0.0041 118 1 0 1 0.777 1.09 PRS_PLINK_1e.06 TRUE 624.2 Atrophy of female genital tract Female 0 1 11 genitourinary black 1, 0 PRS_PLINK_1e.06 TRUE 624.9 stress incontinence, female Female 5 16 11 genitourinary black 16, 5 3, 2 4, 1 4, 0 4, 2 0.26 0.741 0.726 0.139 1.3 0.386 7.08 -0.0698 3.97 0.986 0.006 0.933 0.675 0.991 0.0252 11.4 0.998 0.001 1.03 0.995 1.05 -2.01 3.31 0.544 0.264 0.134 0.00105 156 PRS_PLINK_1e.06 TRUE 625 Pain and other symptoms associated with female genital organs Female 11 20 11 genitourinary black 20, 11 4, 4 5, 2 5, 2 5, 3 0.672 0.774 0.385 0.414 1.96 0.494 12.2 -0.353 1.79 0.843 0.074 0.702 0.0178 131 -2.21 3.08 0.475 0.324 0.11 3.98e-06 63.6 1.15 2.35 0.624 0.205 3.16 0.0869 637 PRS_PLINK_1e.06 TRUE 625.1 Dyspareunia Female 4 14 11 genitourinary black 14, 4 3, 1 3, 1 3, 1 4, 1 1.31 1.24 0.29 0.537 3.7 0.462 12000 0.168 11.3 0.988 0.005 1.18 1.11 1.55 -1.93 20.5 0.925 0.034 0.145 0.125 0.167 -1.68 5.17 0.745 0.128 0.186 0.162 0.222 PRS_PLINK_1e.06 TRUE 626 Disorders of menstruation and other abnormal bleeding from female genital tract Female 15 15 11 genitourinary black 15, 15 3, 3 4, 4 3, 8 4, 0 -0.259 0.53 0.625 0.204 0.772 0.274 1.85 0.299 1.64 0.856 0.068 1.35 0.00973 575 -0.774 2.93 0.792 0.102 0.461 5.98e-06 123 -4.98 4.03 0.216 0.665 0.00686 7.87e-06 1.22 PRS_PLINK_1e.06 TRUE 626.1 Irregular menstrual cycle/bleeding Female 13 15 11 genitourinary black 15, 13 3, 3 4, 4 3, 6 4, 0 -0.229 0.525 0.662 0.179 0.795 0.3 1.87 0.299 1.64 0.856 0.068 1.35 0.00973 575 -0.986 2.84 0.729 0.137 0.373 4.48e-06 116 -4.98 4.03 0.216 0.665 0.00686 7.87e-06 1.22 PRS_PLINK_1e.06 TRUE 626.11 Absent or infrequent menstruation Female 7 10 11 genitourinary black 10, 7 2, 4 2, 2 2, 1 3, 0 0.149 0.83 0.858 0.067 1.16 0.286 5.55 0.243 4.38 0.956 0.02 1.28 0.00166 2670 -7.65 5450 0.999 0 0.000474 2.83e-14 7.82e-05 -2.18 9.17 0.812 0.091 0.112 0.0361 0.105 PRS_PLINK_1e.06 TRUE 626.12 Excessive or frequent menstruation Female 9 13 11 genitourinary black 13, 9 3, 3 3, 3 3, 3 3, 0 -0.616 0.743 0.408 0.39 0.54 0.145 1.69 1.85 5.77 0.749 0.126 6.36 0.00108 18600 -2.46 2.55 0.334 0.476 0.0851 0.000105 3.28 -5.43 8100 0.999 0 0.0044 0.00061 23.4 PRS_PLINK_1e.06 TRUE 626.13 Irregular menstrual cycle Female 6 13 11 genitourinary black 13, 6 3, 1 3, 2 3, 3 3, 0 -0.439 0.742 0.555 0.256 0.645 0.106 2.05 2.92 105 0.978 0.01 18.5 0.0118 29600 -1.81 3.72 0.627 0.202 0.164 0.000536 34.2 0.0623 3750 1 0 1.06 0.125 10.8 PRS_PLINK_1e.06 TRUE 626.14 Irregular menstrual bleeding Female 3 11 11 genitourinary black 11, 3 2, 0 3, 1 2, 2 3, 0 -0.236 1.9 0.902 0.045 0.79 0.0205 20.7 -1.11 3320 1 0 0.329 0.00108 67.1 -0.14 3510 1 0 0.869 0.0885 1.96 PRS_PLINK_1e.06 TRUE 626.15 Infertility, female, associated with anovulation Female 2 6 11 genitourinary black 6, 2 1, 0 1, 0 1, 2 2, 0 -0.432 187 0.998 0.001 0.649 0.119 0.764 -5.23 3.59e+08 1 0 0.00534 1.46e-07 40300 PRS_PLINK_1e.06 TRUE 626.2 Dysmenorrhea Female 5 12 11 genitourinary black 12, 5 2, 1 3, 2 3, 2 3, 0 2.1 1.64 0.199 0.7 8.16 0.505 4000 -0.603 242 0.998 0.001 0.547 0.193 157 2.08 53100000 1 0 8.02 0.000676 214000 1.35 2680 1 0 3.85 1.92e-15 4.54e+13 PRS_PLINK_1e.06 TRUE 626.4 Premenstrual tension syndromes Female 1 2 11 genitourinary black 2, 1 1, 0 1, 1 1, 0 1, 1 -0.335 5910 1 0 0.715 0.64 2.63 -0.127 1880 1 0 0.881 0.736 1.54 PRS_PLINK_1e.06 TRUE 626.8 Infertility, female Female 3 8 11 genitourinary black 8, 3 1, 0 2, 0 2, 3 2, 0 2.79 5.92 0.638 0.195 16.3 0.000347 19 0.015 1380 1 0 1.02 0.426 1.28 PRS_PLINK_1e.06 TRUE 627 Menopausal and postmenopausal disorders Female 7 14 11 genitourinary black 14, 7 3, 2 3, 3 3, 2 4, 0 -0.109 0.644 0.866 0.063 0.897 0.303 2.56 2.62 9.37 0.779 0.108 13.8 12.1 15.9 -0.562 9.84 0.954 0.02 0.57 2.35e-07 1500000 2.53 831 0.998 0.001 12.5 17.3 59.9 PRS_PLINK_1e.06 TRUE 627.1 Postmenopausal bleeding Female 3 8 11 genitourinary black 8, 3 2, 2 2, 0 2, 1 2, 0 -3.88 11.3 0.731 0.136 0.0206 0.0159 0.0273 -0.0908 2530 1 0 0.913 0.576 1.36 0.506 1120 1 0 1.66 0.158 17.7 -0.176 3190 1 0 0.838 0.108 2.75 PRS_PLINK_1e.06 TRUE 627.2 Symptomatic menopause Female 2 14 11 genitourinary black 14, 2 3, 0 3, 1 3, 1 4, 0 -0.73 0.871 0.402 0.396 0.482 0.0289 2.25 -0.457 695 0.999 0 0.633 0.119 4.1 0.0144 293 1 0 1.01 0.103 18.9 PRS_PLINK_1e.06 TRUE 627.21 Symptomatic artificial menopause Female 0 3 11 genitourinary black 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 627.22 Need for Hormone replacement therapy (postmenopausal) Female 0 2 11 genitourinary black 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 627.3 Postmenopausal atrophic vaginitis Female 2 8 11 genitourinary black 8, 2 2, 2 2, 0 2, 0 2, 0 -5.6 34.9 0.872 0.059 0.0037 0.00246 0.00568 -0.0579 1140 1 0 0.944 0.43 1.36 -0.0542 1330 1 0 0.947 0.19 1.7 -0.0945 4780 1 0 0.91 0.276 2.72 PRS_PLINK_1e.06 TRUE 627.4 Premenopausal menorrhagia Female 4 3 11 genitourinary black 3, 4 1, 4 1, 0 1, 0 1, 4 0.214 172 0.999 0 1.24 0.279 8.71 0.0157 406 1 0 1.02 0.747 2.84 -0.109 1500 1 0 0.896 0.135 4.62 PRS_PLINK_1e.06 TRUE 627.5 Premature menopause and other ovarian failure Female 1 3 11 genitourinary black 3, 1 1, 1 1, 0 1, 1 1, 0 0.00215 143 1 0 1 0.541 1.57 PRS_PLINK_1e.06 TRUE 628 Ovarian cyst Female 3 14 11 genitourinary black 14, 3 3, 1 3, 0 3, 2 4, 0 1.16 1.28 0.362 0.441 3.2 0.444 22900 0.501 480 0.999 0 1.65 0.171 19.2 3.28 122 0.979 0.009 26.5 16.2 27.7 -0.0426 136 1 0 0.958 0.558 1.19 PRS_PLINK_1e.06 TRUE 634 Miscarriage; stillbirth Female 4 12 12 pregnancy complications royalblue4 12, 4 2, 2 3, 0 3, 2 3, 0 -0.575 0.988 0.561 0.251 0.563 0.0484 2.73 -0.708 5130 1 0 0.492 0.0496 1.09 -0.733 132 0.996 0.002 0.481 0.00011 2100 -0.161 867 1 0 0.851 0.136 1.78 PRS_PLINK_1e.06 TRUE 634.1 Missed abortion/Hydatidiform mole Female 0 5 12 pregnancy complications royalblue4 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 635 Hemorrhage during pregnancy; childbirth and postpartum Female 2 8 12 pregnancy complications royalblue4 8, 2 2, 0 2, 0 2, 2 2, 0 -0.483 6.15 0.937 0.028 0.617 0.512 0.742 0.0112 189 1 0 1.01 0.707 2.15 PRS_PLINK_1e.06 TRUE 635.2 Antepartum hemorrhage, abruptio placentae, and placenta previa Female 1 6 12 pregnancy complications royalblue4 6, 1 2, 0 1, 1 1, 0 2, 0 -0.692 6590000 1 0 0.501 0.00318 27.3 0.144 12400 1 0 1.16 0.000647 1900 PRS_PLINK_1e.06 TRUE 635.3 Placenta previa and abruptio placenta Female 2 3 12 pregnancy complications royalblue4 3, 2 1, 0 1, 0 0, 2 1, 0 -0.0351 211 1 0 0.965 0.152 2.24 5.66 6.28e+08 1 0 286 2.48e-37 3.29e+28 PRS_PLINK_1e.06 TRUE 636 Early or threatened labor; hemorrhage in early pregnancy Female 4 11 12 pregnancy complications royalblue4 11, 4 2, 2 3, 0 2, 2 3, 0 -1.87 1.48 0.206 0.685 0.154 0.0273 1.09 -0.00384 3460 1 0 0.996 0.421 3.14 -2.73 21.9 0.901 0.045 0.065 0.0137 0.148 -0.0336 988 1 0 0.967 0.0268 3.42 PRS_PLINK_1e.06 TRUE 636.1 Threatened premature labor Female 0 7 12 pregnancy complications royalblue4 7, 0 2 2 1 2 PRS_PLINK_1e.06 TRUE 636.2 Early onset of delivery Female 1 8 12 pregnancy complications royalblue4 8, 1 1, 0 2, 0 2, 1 2, 0 -0.609 177 0.997 0.001 0.544 0.0707 0.678 -0.444 9250 1 0 0.641 0.613 3.27 PRS_PLINK_1e.06 TRUE 636.3 Hemorrhage in early pregnancy Female 3 5 12 pregnancy complications royalblue4 5, 3 2, 2 1, 0 1, 0 1, 1 -0.389 20700 1 0 0.678 0.533 0.911 -0.148 8020 1 0 0.862 0.75 2.45 -0.0209 347 1 0 0.979 0.822 1.13 -0.252 2180 1 0 0.777 0.581 1.64 PRS_PLINK_1e.06 TRUE 636.8 Cervical incompetence Female 0 2 12 pregnancy complications royalblue4 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 637 Short gestation; low birth weight; and fetal growth retardation Both 0 1 12 pregnancy complications royalblue4 1, 0 PRS_PLINK_1e.06 TRUE 642 Hypertension complicating pregnancy, childbirth, and the puerperium Female 2 11 12 pregnancy complications royalblue4 11, 2 2, 1 3, 0 2, 1 3, 0 -0.00892 1.45 0.995 0.002 0.991 0.0808 30.2 0.234 7710 1 0 1.26 0.509 9.48 -0.27 3e+05 1 0 0.763 0.698 1.78 -0.184 2430 1 0 0.832 0.0419 10.7 PRS_PLINK_1e.06 TRUE 642.1 Preeclampsia and eclampsia Female 2 5 12 pregnancy complications royalblue4 5, 2 2, 1 1, 0 1, 1 1, 0 -0.62 8920000 1 0 0.538 0.158 2.64 0.245 4640 1 0 1.28 0.552 1.37 -0.122 2650 1 0 0.886 0.845 2.49 0.454 8780 1 0 1.57 0.352 2.89 PRS_PLINK_1e.06 TRUE 643 Excessive vomiting in pregnancy Female 1 7 12 pregnancy complications royalblue4 7, 1 2, 0 2, 0 1, 1 2, 0 -0.00202 139 1 0 0.998 0.757 2.53 1.91 4170 1 0 6.74 4.13e-13 6.79e+13 PRS_PLINK_1e.06 TRUE 643.1 Hyperemesis gravidarum Female 0 3 12 pregnancy complications royalblue4 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 644 Anemia during pregnancy Female 1 3 12 pregnancy complications royalblue4 3, 1 1, 0 1, 1 1, 0 1, 0 -0.0366 4390 1 0 0.964 0.0264 13.3 -0.48 48100000 1 0 0.619 0.0401 11.3 PRS_PLINK_1e.06 TRUE 646 Other complications of pregnancy NEC Female 2 11 12 pregnancy complications royalblue4 11, 2 3, 0 3, 0 2, 2 3, 0 -0.621 1.36 0.648 0.189 0.537 0.00556 2.95 0.0185 500 1 0 1.02 0.759 1.78 PRS_PLINK_1e.06 TRUE 647 Infectious and parasitic complications affecting pregnancy Female 0 3 12 pregnancy complications royalblue4 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 647.1 Infections of genitourinary tract during pregnancy Female 1 5 12 pregnancy complications royalblue4 5, 1 2, 0 1, 0 1, 1 1, 0 0.165 1370 1 0 1.18 0.104 4.69 -0.00844 609 1 0 0.992 0.988 1.14 PRS_PLINK_1e.06 TRUE 647.3 Major puerperal infection Female 0 1 12 pregnancy complications royalblue4 1, 0 PRS_PLINK_1e.06 TRUE 649 Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium Female 3 12 12 pregnancy complications royalblue4 12, 3 2, 1 3, 0 3, 2 3, 0 -0.635 1.19 0.595 0.226 0.53 0.0708 8.69 -0.0438 6440 1 0 0.957 0.206 4.13 0.0232 77.8 1 0 1.02 0.778 1.1 0.166 1590 1 0 1.18 0.209 2.53 PRS_PLINK_1e.06 TRUE 649.1 Diabetes or abnormal glucose tolerance complicating pregnancy Female 3 13 12 pregnancy complications royalblue4 13, 3 3, 1 3, 0 3, 0 3, 2 -0.46 0.895 0.608 0.216 0.631 0.13 3.48 -0.2 6170 1 0 0.818 0.116 4.64 0.553 167 0.997 0.001 1.74 0.0151 110 11 479 0.982 0.008 62900 30600 129000 PRS_PLINK_1e.06 TRUE 653 Problems associated with amniotic cavity and membranes Female 1 9 12 pregnancy complications royalblue4 9, 1 2, 0 2, 0 2, 1 2, 0 1.42 3.13 0.651 0.187 4.13 0.0775 4.83 0.124 1610 1 0 1.13 0.737 1.15 PRS_PLINK_1e.06 TRUE 654.1 Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium Female 0 4 12 pregnancy complications royalblue4 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 654.2 Rhesus isoimmunization in pregnancy Female 0 3 12 pregnancy complications royalblue4 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 655 Known or suspected fetal abnormality affecting management of mother Female 3 15 12 pregnancy complications royalblue4 15, 3 3, 1 4, 0 3, 2 4, 0 -0.651 0.875 0.457 0.34 0.522 0.1 2.11 1.42 226 0.995 0.002 4.16 3.15 5.46 -2.32 9.19 0.801 0.097 0.0982 0.00768 1.17 -1.53 142 0.991 0.004 0.217 2.91e-09 15500000 PRS_PLINK_1e.06 TRUE 655.1 Abnormality in fetal heart rate or rhythm Female 2 12 12 pregnancy complications royalblue4 12, 2 2, 0 3, 0 3, 2 3, 0 -1.13 1.91 0.553 0.257 0.322 0.000526 9.47 0.0921 127 0.999 0 1.1 1.03 1.28 PRS_PLINK_1e.06 TRUE 656 Other perinatal conditions of fetus or newborn Both 2 13 12 pregnancy complications royalblue4 13, 2 4, 0 3, 0 3, 2 3, 0 -0.286 1.93 0.882 0.054 0.751 0.00241 31.9 0.689 68.5 0.992 0.003 1.99 1.12 7.08 PRS_PLINK_1e.06 TRUE 656.2 Respiratory conditions of fetus and newborn Both 0 3 12 pregnancy complications royalblue4 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 669 Complications of labor and delivery NEC Female 1 15 12 pregnancy complications royalblue4 15, 1 3, 0 4, 0 3, 1 4, 0 -0.185 1.09 0.865 0.063 0.831 0.0048 1730 -0.898 2650 1 0 0.407 0.239 0.167 PRS_PLINK_1e.06 TRUE 671 Venous/cerebrovascular complications embolism in pregnancy and the puerperium Female 0 6 12 pregnancy complications royalblue4 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 674 Other complications of the puerperium NEC Female 0 4 12 pregnancy complications royalblue4 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 676 Other disorders of the breast associated with childbirth and disorders of lactation Female 0 5 12 pregnancy complications royalblue4 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 681 Superficial cellulitis and abscess Both 13 50 13 dermatologic firebrick 50, 13 13, 4 12, 3 12, 2 13, 3 -0.215 0.348 0.538 0.27 0.807 0.407 1.57 -0.748 1.21 0.535 0.271 0.473 0.0422 4.65 -1 1.29 0.438 0.359 0.366 0.00413 3.83 -0.187 0.901 0.836 0.078 0.829 0.14 4.29 PRS_PLINK_1e.06 TRUE 681.1 Cellulitis and abscess of fingers/toes Both 4 24 13 dermatologic firebrick 24, 4 6, 2 6, 0 6, 1 6, 0 -0.734 0.711 0.302 0.52 0.48 0.013 1.71 -1.09 2.98 0.714 0.147 0.335 0.000137 187 -0.934 2.41 0.699 0.156 0.393 0.00165 14.4 -0.641 2.25 0.776 0.11 0.527 3.88e-05 16.9 PRS_PLINK_1e.06 TRUE 681.2 Cellulitis and abscess of face/neck Both 2 21 13 dermatologic firebrick 21, 2 6, 1 5, 1 5, 0 5, 0 -0.193 0.812 0.812 0.09 0.824 0.0879 6.9 0.688 2.45 0.779 0.109 1.99 0.0405 115 -0.153 4.08 0.97 0.013 0.858 0.0013 387 -0.0831 3.88 0.983 0.007 0.92 0.00218 1420 PRS_PLINK_1e.06 TRUE 681.3 Cellulitis and abscess of arm/hand Both 5 30 13 dermatologic firebrick 30, 5 8, 0 7, 4 7, 0 8, 1 -0.0523 0.541 0.923 0.035 0.949 0.306 2.74 1.38 2.34 0.556 0.255 3.96 0.0497 2e+05 0.59 1.57 0.706 0.151 1.8 0.019 84 PRS_PLINK_1e.06 TRUE 681.5 Cellulitis and abscess of leg, except foot Both 5 31 13 dermatologic firebrick 31, 5 8, 0 8, 4 7, 0 8, 1 0.25 0.497 0.614 0.212 1.28 0.463 4.23 0.898 1.8 0.619 0.209 2.46 0.141 259000 0.619 1.91 0.746 0.127 1.86 0.0185 222 PRS_PLINK_1e.06 TRUE 681.6 Cellulitis and abscess of foot, toe Both 5 26 13 dermatologic firebrick 26, 5 7, 0 6, 4 6, 0 7, 1 0.267 0.674 0.692 0.16 1.31 0.0843 5.13 2.36 3.04 0.437 0.359 10.6 0.152 1730000 0.636 1.9 0.738 0.132 1.89 0.0842 412 PRS_PLINK_1e.06 TRUE 681.7 Cellulitis and abscess of trunk Both 2 27 13 dermatologic firebrick 27, 2 7, 0 7, 0 6, 1 7, 1 0.115 0.654 0.86 0.065 1.12 0.16 34.7 0.711 2.73 0.795 0.1 2.04 0.0178 448 0.513 1.49 0.731 0.136 1.67 0.137 133 PRS_PLINK_1e.06 TRUE 686 Other local infections of skin and subcutaneous tissue Both 2 26 13 dermatologic firebrick 26, 2 7, 0 6, 1 6, 0 7, 1 0.0296 0.658 0.964 0.016 1.03 0.134 4.31 1.19 2.73 0.663 0.179 3.3 0.0601 60100 0.718 1.76 0.682 0.166 2.05 0.0942 194 PRS_PLINK_1e.06 TRUE 686.1 Carbuncle and furuncle Both 1 14 13 dermatologic firebrick 14, 1 4, 0 3, 0 3, 0 4, 1 0.244 1.14 0.831 0.08 1.28 0.114 37.7 -0.418 69.3 0.995 0.002 0.658 0.000272 8.52 PRS_PLINK_1e.06 TRUE 686.2 Impetigo Both 0 5 13 dermatologic firebrick 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 686.3 Pilonidal cyst Both 1 6 13 dermatologic firebrick 6, 1 2, 0 1, 1 1, 0 2, 0 1.09 5240000 1 0 2.98 1.81e-05 16.7 -0.0161 1200 1 0 0.984 0.969 1.4 PRS_PLINK_1e.06 TRUE 686.4 Pyogenic granuloma Both 0 3 13 dermatologic firebrick 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 686.5 Pyoderma Both 1 2 13 dermatologic firebrick 2, 1 1, 0 1, 1 1, 0 1, 1 -0.00158 592 1 0 0.998 0.508 1.71 -0.00655 92.6 1 0 0.993 0.898 1.1 PRS_PLINK_1e.06 TRUE 687 Symptoms affecting skin Both 4 18 13 dermatologic firebrick 18, 4 5, 1 4, 1 4, 1 5, 0 -0.189 0.708 0.789 0.103 0.827 0.0778 3.33 1.09 11.5 0.925 0.034 2.97 2.65 3.29 -1.63 5.12 0.751 0.124 0.197 0.175 0.227 -0.337 2.75 0.903 0.044 0.714 0.00275 52 PRS_PLINK_1e.06 TRUE 687.1 Rash and other nonspecific skin eruption Both 22 36 13 dermatologic firebrick 36, 22 9, 5 9, 6 9, 6 9, 5 -0.0815 0.331 0.806 0.094 0.922 0.499 1.71 0.0357 1.09 0.974 0.012 1.04 0.158 6.86 -0.325 1.04 0.754 0.123 0.722 0.073 4.81 -0.661 1.19 0.578 0.238 0.516 0.42 3.63 PRS_PLINK_1e.06 TRUE 687.3 Changes in skin texture Both 2 8 13 dermatologic firebrick 8, 2 2, 0 2, 1 2, 0 2, 0 -0.0686 47.2 0.999 0.001 0.934 0.17 0.975 0.11 46300 1 0 1.12 0.0109 434 PRS_PLINK_1e.06 TRUE 687.4 Disturbance of skin sensation Both 9 36 13 dermatologic firebrick 36, 9 9, 1 9, 5 9, 1 9, 2 0.459 0.483 0.342 0.466 1.58 0.666 4.88 2.71 1.82 0.137 0.865 15.1 0.935 55000 -0.214 1.87 0.909 0.042 0.807 1.8e-05 28.1 1.05 1.28 0.412 0.385 2.85 0.325 62.9 PRS_PLINK_1e.06 TRUE 689 Disorder of skin and subcutaneous tissue NOS Both 16 48 13 dermatologic firebrick 48, 16 12, 3 12, 8 12, 2 12, 2 -0.467 0.384 0.224 0.65 0.627 0.285 1.29 0.785 1.02 0.44 0.357 2.19 0.389 16 -1.45 1.68 0.387 0.413 0.234 4.91e-05 7.35 1.07 1.53 0.483 0.316 2.92 0.122 27300000 PRS_PLINK_1e.06 TRUE 690 Erythematosquamous dermatosis Both 9 32 13 dermatologic firebrick 32, 9 7, 1 8, 4 8, 2 8, 2 0.0207 0.456 0.964 0.016 1.02 0.415 2.8 1.18 1.75 0.499 0.302 3.26 0.22 234 -0.0924 1.76 0.958 0.019 0.912 0.00077 235 0.49 1.71 0.775 0.111 1.63 0.0573 3510 PRS_PLINK_1e.06 TRUE 690.1 Seborrheic dermatitis Both 9 32 13 dermatologic firebrick 32, 9 7, 1 8, 4 8, 2 8, 2 0.0207 0.456 0.964 0.016 1.02 0.415 2.8 1.18 1.75 0.499 0.302 3.26 0.22 234 -0.0924 1.76 0.958 0.019 0.912 0.00077 235 0.49 1.71 0.775 0.111 1.63 0.0573 3510 PRS_PLINK_1e.06 TRUE 691 Congenital anomalies of skin Both 1 10 13 dermatologic firebrick 10, 1 3, 0 2, 0 2, 0 3, 1 3.53 22.5 0.875 0.058 34.2 29.4 40 0.251 2700 1 0 1.29 0.517 15.7 PRS_PLINK_1e.06 TRUE 691.3 Congenital pigmentary anomalies of skin Both 0 2 13 dermatologic firebrick 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 694 Dyschromia and Vitiligo Both 4 22 13 dermatologic firebrick 22, 4 6, 1 5, 2 5, 1 6, 0 1.01 1.07 0.344 0.463 2.74 0.368 99.5 -0.459 1.54 0.765 0.116 0.632 0.0459 6.86 0.372 3.61 0.918 0.037 1.45 1.36 1.53 -1.57 5.07 0.757 0.121 0.209 3.14e-06 430 PRS_PLINK_1e.06 TRUE 694.1 Vitiligo Both 1 3 13 dermatologic firebrick 3, 1 1, 1 1, 0 1, 0 1, 1 0.638 11900 1 0 1.89 0.25 4.43 0.0163 32.1 1 0 1.02 0.946 1.11 0.00902 57.9 1 0 1.01 0.946 1.1 PRS_PLINK_1e.06 TRUE 694.2 Other dyschromia Both 3 19 13 dermatologic firebrick 19, 3 5, 1 5, 2 4, 0 5, 0 0.962 0.983 0.328 0.484 2.62 0.415 30.5 -0.144 1.43 0.92 0.036 0.866 0.0903 7.84 -0.204 24.7 0.993 0.003 0.815 0.074 9.29 -1.67 6.45 0.796 0.099 0.189 7.5e-06 1490 PRS_PLINK_1e.06 TRUE 694.3 Vascular disorders of skin Both 0 1 13 dermatologic firebrick 1, 0 PRS_PLINK_1e.06 TRUE 695 Erythematous conditions Both 13 33 13 dermatologic firebrick 33, 13 8, 1 8, 6 8, 3 8, 3 0.346 0.402 0.389 0.41 1.41 0.693 3.37 1.28 1.68 0.446 0.35 3.59 0.259 155 0.393 1.4 0.779 0.108 1.48 0.000338 32.1 1.58 1.99 0.426 0.37 4.86 0.118 2200 PRS_PLINK_1e.06 TRUE 695.2 Bullous dermatoses Both 0 1 13 dermatologic firebrick 1, 0 PRS_PLINK_1e.06 TRUE 695.3 Rosacea Both 3 18 13 dermatologic firebrick 18, 3 4, 0 4, 1 4, 2 5, 0 -0.582 0.855 0.496 0.304 0.559 0.0619 2.97 0.549 2820000 1 0 1.73 0.0304 116 2.74 476 0.995 0.002 15.5 3.88e-05 341000 PRS_PLINK_1e.06 TRUE 695.4 Lupus (localized and systemic) Both 3 10 13 dermatologic firebrick 10, 3 2, 1 2, 0 2, 0 3, 2 0.556 0.844 0.51 0.292 1.74 0.52 14.1 0.0121 1250 1 0 1.01 0.765 1.39 -0.167 885 1 0 0.847 0.828 1.24 0.21 2510 1 0 1.23 0.43 19.4 PRS_PLINK_1e.06 TRUE 695.41 Cutaneous lupus erythematosus Both 1 3 13 dermatologic firebrick 3, 1 0, 1 1, 0 1, 0 0, 1 -0.198 2720 1 0 0.82 0.163 1.67 0.0174 77.3 1 0 1.02 0.826 1.19 0.0111 64.5 1 0 1.01 0.262 1.35 PRS_PLINK_1e.06 TRUE 695.42 Systemic lupus erythematosus Both 3 9 13 dermatologic firebrick 9, 3 2, 1 2, 0 2, 1 2, 1 0.558 0.837 0.505 0.297 1.75 0.552 7.14 -3.39 8040000 1 0 0.0338 0.000227 28.3 -0.0355 7780 1 0 0.965 7.27e-05 1210 0.0743 1730 1 0 1.08 0.0473 20.9 PRS_PLINK_1e.06 TRUE 695.7 Prurigo and Lichen Both 3 3 13 dermatologic firebrick 3, 3 1, 0 1, 2 1, 1 1, 0 0.0927 1670 1 0 1.1 0.73 2.65 0.145 7330 1 0 1.16 0.348 1.16 -0.00125 74 1 0 0.999 0.921 1.08 PRS_PLINK_1e.06 TRUE 695.8 Other specified erythematous conditions Both 4 7 13 dermatologic firebrick 7, 4 1, 0 2, 1 1, 1 2, 2 1.03 1.43 0.472 0.326 2.79 0.412 30.5 -0.00419 25 1 0 0.996 0.925 1.02 0.00121 129 1 0 1 0.972 1.02 -3.39 7840 1 0 0.0336 3.89e-12 3720000 PRS_PLINK_1e.06 TRUE 695.9 Unspecified erythematous condition Both 0 8 13 dermatologic firebrick 8, 0 2 2 2 2 PRS_PLINK_1e.06 TRUE 696 Psoriasis and related disorders Both 4 9 13 dermatologic firebrick 9, 4 3, 1 2, 0 2, 0 2, 3 -0.365 2.08 0.861 0.065 0.694 0.02 171 0.0447 9440000 1 0 1.05 0.352 2.97 -0.017 13500 1 0 0.983 0.00885 487 0.647 40.2 0.987 0.006 1.91 1.04 1.46e+11 PRS_PLINK_1e.06 TRUE 696.3 Pityriasis Both 1 3 13 dermatologic firebrick 3, 1 1, 0 1, 0 1, 1 1, 0 1.31 1.09e+08 1 0 3.71 0.00815 1920 2.43 17000 1 0 11.4 0.0831 1760 PRS_PLINK_1e.06 TRUE 696.4 Psoriasis Both 3 10 13 dermatologic firebrick 10, 3 3, 1 2, 0 2, 1 3, 1 -0.603 2.13 0.777 0.11 0.547 0.0134 14.5 0.0447 9440000 1 0 1.05 0.352 2.97 0.192 249 0.999 0 1.21 2.92e-05 2430 -0.998 9930000 1 0 0.368 2.57e-08 2040000 PRS_PLINK_1e.06 TRUE 696.41 Psoriasis vulgaris Both 3 8 13 dermatologic firebrick 8, 3 2, 1 2, 0 2, 0 2, 2 -0.0287 2.35 0.99 0.004 0.972 0.0292 562 -0.37 3010 1 0 0.691 0.129 4.66 0.436 6990 1 0 1.55 0.377 4.29 0.417 2440 1 0 1.52 0.0338 511 PRS_PLINK_1e.06 TRUE 696.42 Psoriatic arthropathy Both 1 2 13 dermatologic firebrick 2, 1 1, 0 1, 1 1, 0 1, 1 -0.00548 33.1 1 0 0.995 0.852 1.08 -0.000377 44.8 1 0 1 0.925 1.09 PRS_PLINK_1e.06 TRUE 697 Sarcoidosis Both 0 4 13 dermatologic firebrick 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 698 Pruritus and related conditions Both 3 33 13 dermatologic firebrick 33, 3 9, 2 8, 1 8, 0 8, 0 -0.178 0.791 0.822 0.085 0.837 0.15 5.56 -0.491 1.4 0.726 0.139 0.612 0.0345 8.17 -1.32 2.02 0.512 0.29 0.267 0.00119 19.9 -0.848 1.83 0.643 0.192 0.428 0.00405 18.2 PRS_PLINK_1e.06 TRUE 700 Corns and callosities Both 10 20 13 dermatologic firebrick 20, 10 5, 3 5, 3 5, 1 5, 2 -0.423 0.653 0.517 0.286 0.655 0.173 1.9 0.517 1.72 0.763 0.117 1.68 0.0984 22.6 -3.88 4.08 0.342 0.466 0.0207 8.26e-06 7.91 -2.71 2.6 0.299 0.525 0.0667 2.87e-05 2.5 PRS_PLINK_1e.06 TRUE 701 Other hypertrophic and atrophic conditions of skin Both 9 47 13 dermatologic firebrick 47, 9 12, 3 12, 3 11, 2 12, 1 -0.274 0.402 0.496 0.304 0.761 0.33 1.67 0.771 1.29 0.55 0.26 2.16 0.217 64.4 -1.03 1.38 0.456 0.341 0.358 0.00491 3.29 -1.38 1.41 0.328 0.485 0.252 0.00395 3.6 PRS_PLINK_1e.06 TRUE 701.1 Keratoderma, acquired Both 2 8 13 dermatologic firebrick 8, 2 2, 0 2, 2 2, 0 2, 0 0.869 4.78 0.856 0.068 2.39 0.0633 2.52 -0.0124 87 1 0 0.988 0.717 1.56 PRS_PLINK_1e.06 TRUE 701.2 Scar conditions and fibrosis of skin Both 1 24 13 dermatologic firebrick 24, 1 6, 0 6, 0 6, 1 6, 0 0.276 0.8 0.73 0.137 1.32 0.11 16.6 -0.512 4.72 0.914 0.039 0.599 6.77e-05 362000 PRS_PLINK_1e.06 TRUE 701.3 Circumscribed scleroderma Both 1 8 13 dermatologic firebrick 8, 1 2, 1 2, 0 2, 0 2, 0 0.0468 2150 1 0 1.05 0.8 1.79 -0.0708 50700 1 0 0.932 0.391 12 -0.33 12200 1 0 0.719 0.0345 10.5 -0.18 23700 1 0 0.836 0.259 1.95 PRS_PLINK_1e.06 TRUE 701.4 Keloid scar Both 0 5 13 dermatologic firebrick 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 701.5 Abnormal granulation tissue Both 0 4 13 dermatologic firebrick 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 702 Degenerative skin conditions and other dermatoses Both 11 31 13 dermatologic firebrick 31, 11 8, 5 8, 1 7, 2 8, 3 0.733 0.73 0.316 0.5 2.08 0.517 87.5 0.888 1.81 0.623 0.205 2.43 0.103 4130 1.08 2.13 0.613 0.213 2.94 0.00278 45700 1.59 1.56 0.307 0.512 4.89 0.0752 983 PRS_PLINK_1e.06 TRUE 702.1 Actinic keratosis Both 3 28 13 dermatologic firebrick 28, 3 6, 0 7, 2 7, 1 7, 0 -0.168 0.678 0.804 0.095 0.845 0.0903 7.81 -0.348 2.08 0.867 0.062 0.706 0.00273 49.5 0.0174 4.5 0.997 0.001 1.02 6.36e-06 18700 PRS_PLINK_1e.06 TRUE 702.2 Seborrheic keratosis Both 9 32 13 dermatologic firebrick 32, 9 7, 1 8, 2 8, 3 8, 3 0.4 0.599 0.504 0.298 1.49 0.372 22.1 -0.42 1.81 0.817 0.088 0.657 0.0137 13.7 -0.775 2.29 0.736 0.133 0.461 0.000545 22800 1.14 1.43 0.427 0.369 3.12 0.218 1400 PRS_PLINK_1e.06 TRUE 702.4 Degenerative skin disorders Both 0 1 13 dermatologic firebrick 1, 0 PRS_PLINK_1e.06 TRUE 703 Diseases of nail, NOS Both 8 20 13 dermatologic firebrick 20, 8 5, 5 5, 1 5, 1 5, 1 0.000652 0.583 0.999 0 1 0.423 2.68 -0.262 1.57 0.867 0.062 0.769 0.0657 11.7 -0.438 1.87 0.815 0.089 0.645 0.024 15.1 -2.84 2.67 0.288 0.541 0.0586 5.43e-14 3.25 PRS_PLINK_1e.06 TRUE 703.1 Ingrowing nail Both 5 18 13 dermatologic firebrick 18, 5 5, 4 4, 0 4, 0 5, 1 -1.02 0.94 0.277 0.558 0.36 0.000135 1.69 1.16 4.57 0.8 0.097 3.19 0.00186 22100 0.0158 2.48 0.995 0.002 1.02 0.00178 224 -3.87 4.01 0.334 0.476 0.0209 3.2e-05 5.31 PRS_PLINK_1e.06 TRUE 704 Diseases of hair and hair follicles Both 9 40 13 dermatologic firebrick 40, 9 9, 1 10, 3 10, 0 10, 5 0.255 0.425 0.549 0.261 1.29 0.596 3.53 0.68 1.98 0.731 0.136 1.97 0.0932 159000 -0.978 1.93 0.612 0.213 0.376 0.00188 44.8 1.68 1.28 0.188 0.726 5.37 0.72 72.5 PRS_PLINK_1e.06 TRUE 704.1 Alopecia Both 2 17 13 dermatologic firebrick 17, 2 5, 1 4, 0 4, 0 4, 1 -0.205 1.17 0.861 0.065 0.815 0.094 93.4 -0.777 96.2 0.994 0.003 0.46 7.2e-11 2.45e+09 1.83 192 0.992 0.003 6.22 0.000781 1680 0.749 3.89 0.847 0.072 2.12 1.95 2.24 PRS_PLINK_1e.06 TRUE 704.11 Alopecia Areata Both 1 2 13 dermatologic firebrick 2, 1 1, 0 0, 1 1, 0 1, 0 -0.00984 88.7 1 0 0.99 0.908 1.08 -0.00315 37.8 1 0 0.997 0.951 1.17 PRS_PLINK_1e.06 TRUE 704.2 Hirsutism Both 3 3 13 dermatologic firebrick 3, 3 1, 1 1, 1 1, 1 1, 1 4.98 1240 0.997 0.001 145 3.72e-23 5.85e+14 0.492 2700 1 0 1.64 0.604 1.68 -0.539 34700 1 0 0.584 5.68e-23 3.12 PRS_PLINK_1e.06 TRUE 704.8 Other specified diseases of hair and hair follicles Both 7 24 13 dermatologic firebrick 24, 7 5, 3 6, 0 6, 1 6, 3 0.321 0.494 0.516 0.288 1.38 0.607 3.84 -2.6 2.92 0.373 0.429 0.0741 0.000158 5.83 -1.45 1.89 0.443 0.353 0.235 0.00428 10.3 -0.118 1.38 0.932 0.031 0.888 0.0993 7.83 PRS_PLINK_1e.06 TRUE 705 Disorders of sweat glands Both 1 7 13 dermatologic firebrick 7, 1 2, 0 2, 0 1, 1 2, 0 -0.245 377 0.999 0 0.783 0.354 1.1 0.515 9070 1 0 1.67 0.417 2.46 PRS_PLINK_1e.06 TRUE 705.1 Dyshidrosis Both 0 1 13 dermatologic firebrick 1, 0 PRS_PLINK_1e.06 TRUE 705.3 Hidradenitis Both 0 5 13 dermatologic firebrick 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 705.8 Hyperhidrosis Both 3 15 13 dermatologic firebrick 15, 3 4, 1 4, 0 3, 1 4, 1 0.371 1.18 0.753 0.123 1.45 0.0033 350 -3.06 26.7 0.909 0.041 0.0469 0.00204 0.0809 -0.122 418 1 0 0.885 0.511 1.1 0.764 7.12 0.915 0.039 2.15 1.95 2.33 PRS_PLINK_1e.06 TRUE 706 Diseases of sebaceous glands Both 19 43 13 dermatologic firebrick 43, 19 11, 4 11, 2 10, 6 11, 6 0.0311 0.312 0.921 0.036 1.03 0.58 1.85 1.65 1.84 0.369 0.433 5.22 0.191 1960 0.312 0.907 0.731 0.136 1.37 0.294 6.91 0.564 0.984 0.567 0.247 1.76 0.299 13.7 PRS_PLINK_1e.06 TRUE 706.1 Acne Both 6 32 13 dermatologic firebrick 32, 6 8, 2 8, 0 8, 3 8, 1 0.105 0.467 0.822 0.085 1.11 0.49 2.84 -1.65 1.92 0.389 0.41 0.192 0.000486 4.62 0.743 1.46 0.61 0.214 2.1 0.198 853 -0.378 1.35 0.779 0.109 0.685 0.00269 6.94 PRS_PLINK_1e.06 TRUE 706.2 Sebaceous cyst Both 9 29 13 dermatologic firebrick 29, 9 8, 0 7, 1 7, 3 7, 5 0.557 0.549 0.311 0.508 1.75 0.691 5.64 0.346 3.98 0.931 0.031 1.41 0.000202 13900000 1.65 1.58 0.298 0.525 5.18 0.285 345 2.71 1.85 0.143 0.843 15 1 6060 PRS_PLINK_1e.06 TRUE 706.3 Seborrhea Both 0 1 13 dermatologic firebrick 1, 0 PRS_PLINK_1e.06 TRUE 706.8 Other specified diseases of sebaceous glands Both 9 18 13 dermatologic firebrick 18, 9 5, 2 4, 1 4, 2 5, 3 0.851 0.824 0.301 0.521 2.34 0.524 14.3 1.82 4.6 0.692 0.16 6.2 0.00138 7930 0.596 2.29 0.794 0.1 1.81 0.0646 30300 1.3 3.98 0.743 0.129 3.69 1.3e-05 10200 PRS_PLINK_1e.06 TRUE 707 Chronic ulcer of skin Both 7 35 13 dermatologic firebrick 35, 7 8, 1 9, 2 8, 1 9, 3 0.524 0.471 0.266 0.576 1.69 0.747 5.06 1.72 2.33 0.462 0.336 5.56 0.122 2600 2.05 2.41 0.395 0.404 7.79 0.0183 4840 1.06 1.32 0.421 0.375 2.89 0.222 867 PRS_PLINK_1e.06 TRUE 707.1 Decubitus ulcer Both 2 14 13 dermatologic firebrick 14, 2 4, 1 3, 0 3, 0 4, 1 0.236 1.14 0.836 0.078 1.27 0.12 65.2 -0.0279 49.6 1 0 0.972 0.0522 1.43 -0.137 2200 1 0 0.872 0.333 0.803 0.855 5.63 0.879 0.056 2.35 7.14e-05 5910 PRS_PLINK_1e.06 TRUE 707.2 Chronic ulcer of leg or foot Both 4 21 13 dermatologic firebrick 21, 4 6, 0 5, 1 5, 0 5, 3 0.524 0.587 0.372 0.429 1.69 0.578 5.91 0.354 2.55 0.89 0.051 1.42 0.0323 89.9 0.476 1.63 0.77 0.113 1.61 0.0913 29.1 PRS_PLINK_1e.06 TRUE 707.3 Chronic ulcer of unspecified site Both 2 21 13 dermatologic firebrick 21, 2 6, 0 5, 1 5, 1 5, 0 0.206 0.778 0.791 0.102 1.23 0.116 64.5 -0.253 3.63 0.944 0.025 0.776 0.000161 432 1.27 2.7 0.638 0.195 3.56 0.0472 205 PRS_PLINK_1e.06 TRUE 709 Diffuse diseases of connective tissue Both 5 18 13 dermatologic firebrick 18, 5 4, 2 4, 2 4, 0 5, 1 0.165 0.863 0.848 0.071 1.18 0.154 9.44 0.379 2.1 0.857 0.067 1.46 0.0472 108 -1.43 5.79 0.805 0.094 0.24 0.195 3.71 -2.34 4.48 0.601 0.221 0.0962 1.38e-05 56.3 PRS_PLINK_1e.06 TRUE 709.2 Sicca syndrome Both 3 7 13 dermatologic firebrick 7, 3 1, 2 2, 0 1, 0 2, 1 -0.263 4.33 0.952 0.022 0.769 0.601 0.945 0.986 17900000 1 0 2.68 6.25e-10 119000 -0.238 14800000 1 0 0.789 0.113 4.12 -0.391 3270 1 0 0.677 0.527 2.28 PRS_PLINK_1e.06 TRUE 709.7 Unspecified diffuse connective tissue disease Both 3 14 13 dermatologic firebrick 14, 3 4, 1 3, 2 3, 0 4, 0 -0.597 1.59 0.707 0.15 0.551 0.00623 22.8 -0.168 4.64 0.971 0.013 0.845 0.000614 1150 -1.83 9340 1 0 0.161 0.00429 46.9 -3.5 6860000 1 0 0.0301 8.46e-05 44.9 PRS_PLINK_1e.06 TRUE 710 Osteomyelitis, periostitis, and other infections involving bone Both 2 17 14 musculoskeletal darkolivegreen 17, 2 5, 0 4, 0 4, 0 4, 1 -0.0519 1.01 0.959 0.018 0.949 0.00592 15 -4.65e-15 4.08 1 0 1 0.00202 622 PRS_PLINK_1e.06 TRUE 710.1 Osteomyelitis Both 2 18 14 musculoskeletal darkolivegreen 18, 2 5, 0 4, 0 4, 0 5, 1 -0.31 1.06 0.77 0.113 0.734 0.00606 19.1 -0.0462 3.68 0.99 0.004 0.955 0.00399 2240 PRS_PLINK_1e.06 TRUE 710.11 Acute osteomyelitis Both 0 8 14 musculoskeletal darkolivegreen 8, 0 2 2 2 2 PRS_PLINK_1e.06 TRUE 710.12 Chronic osteomyelitis Both 0 10 14 musculoskeletal darkolivegreen 10, 0 3 2 2 3 PRS_PLINK_1e.06 TRUE 710.19 Unspecified osteomyelitis Both 2 18 14 musculoskeletal darkolivegreen 18, 2 5, 0 4, 0 4, 0 5, 1 -0.215 1.05 0.837 0.077 0.807 0.00608 16.1 0.0587 2.98 0.984 0.007 1.06 0.000631 111 PRS_PLINK_1e.06 TRUE 711 Arthropathy associated with infections Both 0 6 14 musculoskeletal darkolivegreen 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 711.1 Pyogenic arthritis Both 0 2 14 musculoskeletal darkolivegreen 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 712 Infective connective tissue disorders Both 0 1 14 musculoskeletal darkolivegreen 1, 0 PRS_PLINK_1e.06 TRUE 713 Arthropathy associated with other disorders classified elsewhere Both 3 9 14 musculoskeletal darkolivegreen 9, 3 3, 0 2, 1 2, 1 2, 0 0.107 134 0.999 0 1.11 0.915 2.27 0.2 371 1 0 1.22 0.579 1.28 0.041 1830 1 0 1.04 0.262 4.32 PRS_PLINK_1e.06 TRUE 713.5 Arthropathy associated with neurological disorders Both 3 6 14 musculoskeletal darkolivegreen 6, 3 2, 0 1, 0 1, 1 2, 1 0.359 530 0.999 0 1.43 1.5 2.4 0.0137 33.5 1 0 1.01 0.897 1.23 0.909 99800000 1 0 2.48 0.000341 8040 PRS_PLINK_1e.06 TRUE 714 Rheumatoid arthritis and other inflammatory polyarthropathies Both 4 19 14 musculoskeletal darkolivegreen 19, 4 5, 1 5, 0 4, 1 5, 2 0.229 0.808 0.777 0.11 1.26 0.291 8.4 7.74 33 0.814 0.089 2300 1300 4000 -7.21 14.7 0.624 0.205 0.000738 1.15e-14 194000 0.234 1.78 0.896 0.048 1.26 0.104 6000 PRS_PLINK_1e.06 TRUE 714.1 Rheumatoid arthritis Both 1 13 14 musculoskeletal darkolivegreen 13, 1 4, 1 3, 0 3, 0 3, 0 -1.52 2.36 0.521 0.283 0.219 7.22e-05 9.92 2.3 3510000 1 0 9.98 0.284 350 -1.19 9770 1 0 0.305 0.000122 1.39 0.031 1020 1 0 1.03 0.808 1.41 PRS_PLINK_1e.06 TRUE 714.2 Juvenile rheumatoid arthritis Both 0 2 14 musculoskeletal darkolivegreen 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 715 Other inflammatory spondylopathies Both 4 8 14 musculoskeletal darkolivegreen 8, 4 2, 1 2, 1 2, 0 2, 2 1.53 1.63 0.348 0.458 4.62 0.553 189 5.05 1650 0.998 0.001 156 0.0195 6230000 0.307 3010 1 0 1.36 0.425 1.4 0.0548 502 1 0 1.06 0.743 1.5 PRS_PLINK_1e.06 TRUE 715.1 Sacroiliitis NEC Both 2 1 14 musculoskeletal darkolivegreen 1, 2 0.277 523000 1 0 1.32 0.301 4.88 PRS_PLINK_1e.06 TRUE 715.2 Ankylosing spondylitis Both 1 3 14 musculoskeletal darkolivegreen 3, 1 1, 0 1, 0 0, 1 1, 0 0.0458 908 1 0 1.05 0.881 1.52 -0.00144 77.7 1 0 0.999 0.951 1.06 PRS_PLINK_1e.06 TRUE 716 Other arthropathies Both 18 42 14 musculoskeletal darkolivegreen 42, 18 11, 4 10, 5 10, 1 11, 7 0.404 0.367 0.272 0.566 1.5 0.771 3.15 -1.1 1.37 0.42 0.377 0.332 0.0108 3.51 -0.0927 1.59 0.953 0.021 0.911 0.000172 52.5 3.77 1.99 0.0587 1.231 43.2 1.76 111000 PRS_PLINK_1e.06 TRUE 716.1 Unspecified polyarthropathy or polyarthritis Both 1 0 14 musculoskeletal darkolivegreen 0, 1 PRS_PLINK_1e.06 TRUE 716.9 Arthropathy NOS Both 18 42 14 musculoskeletal darkolivegreen 42, 18 11, 4 10, 5 10, 1 11, 7 0.404 0.367 0.272 0.566 1.5 0.771 3.15 -1.1 1.37 0.42 0.377 0.332 0.0108 3.51 -0.0927 1.59 0.953 0.021 0.911 0.000172 52.5 3.77 1.99 0.0587 1.231 43.2 1.76 111000 PRS_PLINK_1e.06 TRUE 717 Polymyalgia Rheumatica Both 1 3 14 musculoskeletal darkolivegreen 3, 1 1, 1 1, 0 1, 0 1, 1 -0.644 67700 1 0 0.525 0.00048 1.91e+08 -0.088 202 1 0 0.916 0.714 1.26 -0.0255 108 1 0 0.975 0.934 1.19 PRS_PLINK_1e.06 TRUE 720 Spinal stenosis Both 1 28 14 musculoskeletal darkolivegreen 28, 1 6, 0 7, 1 7, 0 7, 0 -0.0656 0.536 0.903 0.045 0.937 0.269 3.28 0.468 2.42 0.847 0.072 1.6 0.0148 285 PRS_PLINK_1e.06 TRUE 720.1 Spinal stenosis of lumbar region Both 0 24 14 musculoskeletal darkolivegreen 24, 0 5 6 6 6 PRS_PLINK_1e.06 TRUE 721 Spondylosis and allied disorders Both 8 42 14 musculoskeletal darkolivegreen 42, 8 10, 0 10, 4 10, 4 11, 0 0.283 0.528 0.593 0.227 1.33 0.463 4.89 -0.0725 1.72 0.966 0.015 0.93 0.00588 71.9 1.86 1.67 0.265 0.577 6.45 0.409 1170 PRS_PLINK_1e.06 TRUE 721.1 Spondylosis without myelopathy Both 7 41 14 musculoskeletal darkolivegreen 41, 7 10, 0 10, 4 10, 3 10, 0 0.186 0.54 0.731 0.136 1.2 0.388 4.71 -0.0725 1.72 0.966 0.015 0.93 0.00588 71.9 0.875 1.45 0.545 0.263 2.4 0.15 94.6 PRS_PLINK_1e.06 TRUE 721.2 Spondylosis with myelopathy Both 0 6 14 musculoskeletal darkolivegreen 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 721.8 Other allied disorders of spine Both 1 4 14 musculoskeletal darkolivegreen 4, 1 1, 0 1, 0 1, 0 1, 1 0.772 27100 1 0 2.16 3.16e-05 215000 0.152 72.3 0.998 0.001 1.16 0.734 1.48 PRS_PLINK_1e.06 TRUE 722 Intervertebral disc disorders Both 4 48 14 musculoskeletal darkolivegreen 48, 4 11, 0 12, 4 12, 0 12, 0 0.0083 0.654 0.99 0.004 1.01 0.0223 7.83 -0.0645 1.65 0.969 0.014 0.937 0.0181 434 PRS_PLINK_1e.06 TRUE 722.1 Displacement of intervertebral disc Both 1 39 14 musculoskeletal darkolivegreen 39, 1 9, 0 10, 1 9, 0 10, 0 0.0951 0.572 0.868 0.062 1.1 0.189 18.2 0.679 1.94 0.726 0.139 1.97 0.00311 863 PRS_PLINK_1e.06 TRUE 722.6 Degeneration of intervertebral disc Both 3 35 14 musculoskeletal darkolivegreen 35, 3 8, 0 9, 2 8, 1 9, 0 0.014 0.61 0.982 0.008 1.01 0.21 5.39 -0.529 1.89 0.78 0.108 0.589 4.74e-05 38.7 0.0761 1.92 0.968 0.014 1.08 0.000478 433 PRS_PLINK_1e.06 TRUE 722.7 Intervertebral disc disorder with myelopathy Both 0 6 14 musculoskeletal darkolivegreen 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 722.8 Postlaminectomy syndrome Both 1 9 14 musculoskeletal darkolivegreen 9, 1 2, 0 2, 1 2, 0 2, 0 -1.63 2.77 0.557 0.254 0.197 0.00117 6.54 -0.0155 38.4 1 0 0.985 0.834 1.06 PRS_PLINK_1e.06 TRUE 722.9 Other and unspecified disc disorder Both 1 27 14 musculoskeletal darkolivegreen 27, 1 6, 0 7, 1 6, 0 7, 0 -0.325 0.584 0.578 0.238 0.723 0.168 6.13 0.0801 2.23 0.971 0.013 1.08 0.0139 97.6 PRS_PLINK_1e.06 TRUE 723 Other disorders of cervical region Both 2 14 14 musculoskeletal darkolivegreen 14, 2 3, 0 3, 2 3, 0 4, 0 -0.329 1.2 0.785 0.105 0.72 0.0611 6.45 2.21 728 0.998 0.001 9.15 13.9 106 PRS_PLINK_1e.06 TRUE 723.1 Torticollis Both 0 6 14 musculoskeletal darkolivegreen 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 724 Other and unspecified disorders of back Both 4 40 14 musculoskeletal darkolivegreen 40, 4 9, 0 10, 3 10, 1 10, 0 0.137 0.578 0.813 0.09 1.15 0.376 7.24 1.02 1.46 0.485 0.314 2.77 0.238 296 0.123 1.35 0.927 0.033 1.13 0.0332 25.3 PRS_PLINK_1e.06 TRUE 724.1 Disorders of sacrum Both 3 31 14 musculoskeletal darkolivegreen 31, 3 7, 0 8, 2 7, 1 8, 0 -0.0385 0.687 0.955 0.02 0.962 0.18 23.2 0.00204 1.66 0.999 0 1 0.00333 329 0.503 1.88 0.789 0.103 1.65 0.0462 1370 PRS_PLINK_1e.06 TRUE 724.2 Disorders of coccyx Both 0 7 14 musculoskeletal darkolivegreen 7, 0 2 2 1 2 PRS_PLINK_1e.06 TRUE 724.8 Other symptoms referable to back Both 0 14 14 musculoskeletal darkolivegreen 14, 0 4 3 3 4 PRS_PLINK_1e.06 TRUE 724.9 Other unspecified back disorders Both 2 15 14 musculoskeletal darkolivegreen 15, 2 3, 0 4, 1 3, 1 4, 0 -0.383 1 0.703 0.153 0.682 0.077 5.06 0.478 5.4e+07 1 0 1.61 0.03 124 -10.6 161 0.948 0.023 2.48e-05 2.83e-17 2.57e-05 PRS_PLINK_1e.06 TRUE 726 Peripheral enthesopathies and allied syndromes Both 23 23 14 musculoskeletal darkolivegreen 23, 23 6, 0 6, 10 5, 6 6, 7 0.369 0.403 0.359 0.444 1.45 0.721 3.27 2.17 2.11 0.303 0.518 8.78 0.529 1.87e+13 2.47 1.97 0.209 0.679 11.8 0.64 629000 1.63 1.76 0.353 0.452 5.1 0.0621 325 PRS_PLINK_1e.06 TRUE 726.1 Enthesopathy Both 18 23 14 musculoskeletal darkolivegreen 23, 18 6, 0 6, 8 5, 3 6, 7 0.259 0.415 0.532 0.274 1.3 0.628 3 1.81 1.98 0.359 0.445 6.14 0.412 2.71e+11 1.35 2.51 0.589 0.23 3.86 0.0302 1160 1.63 1.76 0.353 0.452 5.1 0.0621 325 PRS_PLINK_1e.06 TRUE 726.2 Synoviopathy Both 2 6 14 musculoskeletal darkolivegreen 6, 2 2, 0 1, 1 1, 0 2, 1 -0.289 1820000 1 0 0.749 0.224 2.42 -0.472 7.17e+08 1 0 0.624 0.0368 17.1 -0.000347 169 1 0 1 0.936 1.06 PRS_PLINK_1e.06 TRUE 726.3 Bursitis Both 5 10 14 musculoskeletal darkolivegreen 10, 5 3, 2 2, 2 2, 0 3, 1 -0.0997 0.828 0.904 0.044 0.905 0.196 5.53 -0.0435 190 1 0 0.957 0.107 3.04 0.0188 1780 1 0 1.02 0.193 1.55 0.983 1010 0.999 0 2.67 0.388 5.1 PRS_PLINK_1e.06 TRUE 726.4 Calcaneal spur; Exostosis NOS Both 4 8 14 musculoskeletal darkolivegreen 8, 4 2, 0 2, 1 2, 2 2, 1 -0.973 2.9 0.737 0.132 0.378 0.000673 117 0.00295 18.4 1 0 1 0.867 1.03 -0.181 213 0.999 0 0.834 0.334 1.3 -0.00288 15.1 1 0 0.997 0.926 1.07 PRS_PLINK_1e.06 TRUE 727 Other disorders of synovium, tendon, and bursa Both 25 22 14 musculoskeletal darkolivegreen 22, 25 6, 2 5, 11 5, 6 6, 6 0.0762 0.349 0.827 0.082 1.08 0.573 2.07 9.67 5.79 0.0947 1.024 15800 1.18 29700 1.65 1.97 0.402 0.396 5.2 0.171 11300000 1.08 1.54 0.483 0.316 2.95 0.189 99.3 PRS_PLINK_1e.06 TRUE 727.1 Synovitis and tenosynovitis Both 11 17 14 musculoskeletal darkolivegreen 17, 11 5, 1 4, 7 4, 1 4, 2 -0.232 0.494 0.639 0.195 0.793 0.304 1.94 1.55 1.92 0.419 0.378 4.7 0.266 600 2.12 6.68 0.751 0.124 8.3 5.65e-05 238000 2.17 2.97 0.465 0.332 8.73 0.0481 10.7 PRS_PLINK_1e.06 TRUE 727.2 Bursitis disorders Both 0 2 14 musculoskeletal darkolivegreen 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 727.4 Ganglion and cyst of synovium, tendon, and bursa Both 2 8 14 musculoskeletal darkolivegreen 8, 2 2, 0 2, 1 2, 1 2, 0 0.334 1.79 0.852 0.069 1.4 1.36 1.43 0.0498 1970 1 0 1.05 0.46 2.56 -0.0363 5550 1 0 0.964 0.351 1.88 PRS_PLINK_1e.06 TRUE 727.5 Rupture of synovium Both 1 1 14 musculoskeletal darkolivegreen 1, 1 4.29 242 0.986 0.006 72.9 1.22e-10 27100000 PRS_PLINK_1e.06 TRUE 727.6 Rupture of tendon, nontraumatic Both 8 12 14 musculoskeletal darkolivegreen 12, 8 3, 0 3, 2 3, 4 3, 2 0.416 0.844 0.622 0.206 1.52 0.37 11.4 2.66 359 0.994 0.003 14.3 0.000355 30500 1.99 26.7 0.941 0.027 7.32 5.41 9.49 -0.0662 499 1 0 0.936 0.0978 12.5 PRS_PLINK_1e.06 TRUE 727.7 Contracture of tendon (sheath) Both 0 4 14 musculoskeletal darkolivegreen 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 727.8 Plica syndrome Both 3 0 14 musculoskeletal darkolivegreen 0, 3 PRS_PLINK_1e.06 TRUE 728 Disorders of muscle, ligament, and fascia Both 9 20 14 musculoskeletal darkolivegreen 20, 9 5, 2 5, 1 5, 4 5, 2 0.536 0.637 0.4 0.397 1.71 0.5 12.2 -0.11 1.95 0.955 0.02 0.895 0.0389 57.5 0.268 2.24 0.905 0.043 1.31 0.0353 121 0.89 3.8 0.815 0.089 2.43 0.0035 189000 PRS_PLINK_1e.06 TRUE 728.2 Laxity of ligament or hypermobility syndrome Both 1 1 14 musculoskeletal darkolivegreen 1, 1 -0.013 84.8 1 0 0.987 0.678 1.25 PRS_PLINK_1e.06 TRUE 728.7 Fasciitis Both 11 14 14 musculoskeletal darkolivegreen 14, 11 4, 1 3, 5 3, 3 4, 1 -0.0471 0.651 0.942 0.026 0.954 0.239 3.77 2.34 5.66 0.68 0.168 10.3 0.00169 78800000 -0.975 4.95 0.844 0.074 0.377 0.335 0.473 1.45 391 0.997 0.001 4.25 2.81 2740 PRS_PLINK_1e.06 TRUE 728.71 Contracture of palmar fascia [Dupuytren's disease] Both 1 2 14 musculoskeletal darkolivegreen 2, 1 1, 1 1, 0 1, 1 1, 0 -0.00533 54.1 1 0 0.995 0.97 1.07 -0.0115 59.5 1 0 0.989 0.966 1.19 PRS_PLINK_1e.06 TRUE 729 Other disorders of soft tissues Both 10 20 14 musculoskeletal darkolivegreen 20, 10 5, 0 5, 7 5, 1 5, 2 -0.202 0.488 0.679 0.168 0.817 0.331 1.93 3.69 3.66 0.312 0.505 40.2 0.126 3880000 -1.05 5.67 0.854 0.069 0.351 4.69e-06 688 1.2 2.33 0.607 0.217 3.31 0.0838 274 PRS_PLINK_1e.06 TRUE 729.7 Nontraumatic compartment syndrome Both 0 1 14 musculoskeletal darkolivegreen 1, 0 PRS_PLINK_1e.06 TRUE 731 Osteitis deformans and osteopathies associated with other disorders classified elsewhere Both 0 8 14 musculoskeletal darkolivegreen 8, 0 2 2 2 2 PRS_PLINK_1e.06 TRUE 732 Osteochondropathies Both 1 4 14 musculoskeletal darkolivegreen 4, 1 1, 0 1, 0 1, 0 1, 1 -0.028 1160 1 0 0.972 0.123 12.1 -0.0217 27.9 0.999 0 0.979 0.952 1.46 PRS_PLINK_1e.06 TRUE 732.1 Juvenile osteochondrosis Both 1 0 14 musculoskeletal darkolivegreen 0, 1 PRS_PLINK_1e.06 TRUE 732.7 Osteochondritis dissecans Both 0 2 14 musculoskeletal darkolivegreen 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 733 Other disorders of bone and cartilage Both 5 30 14 musculoskeletal darkolivegreen 30, 5 8, 3 7, 0 7, 0 8, 2 -0.414 0.631 0.512 0.291 0.661 0.162 2.29 -0.788 2.04 0.699 0.155 0.455 0.00329 424 -1.38 1.89 0.465 0.333 0.251 0.00222 12.4 0.323 1.26 0.798 0.098 1.38 0.126 21.2 PRS_PLINK_1e.06 TRUE 733.2 Cyst of bone Both 0 2 14 musculoskeletal darkolivegreen 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 733.4 Aseptic necrosis of bone Both 1 5 14 musculoskeletal darkolivegreen 5, 1 2, 0 1, 1 1, 0 1, 0 0.0139 1180 1 0 1.01 0.79 2.45 -0.131 2020 1 0 0.877 0.389 1.24 PRS_PLINK_1e.06 TRUE 733.6 Costochondritis Both 1 2 14 musculoskeletal darkolivegreen 2, 1 1, 0 1, 1 1, 0 1, 1 -0.000208 2510 1 0 1 0.529 1.83 0.479 6770 1 0 1.61 0.384 1.68 PRS_PLINK_1e.06 TRUE 733.8 Malunion and nonunion of fracture Both 0 12 14 musculoskeletal darkolivegreen 12, 0 3 3 3 3 PRS_PLINK_1e.06 TRUE 735 Acquired foot deformities Both 11 35 14 musculoskeletal darkolivegreen 35, 11 9, 4 9, 4 8, 0 9, 2 -0.823 0.485 0.0893 1.049 0.439 0.141 0.992 0.418 1.3 0.747 0.126 1.52 0.0736 20.7 -1.13 1.57 0.471 0.327 0.322 0.000509 11.1 -0.772 1.1 0.484 0.315 0.462 0.0497 3.09 PRS_PLINK_1e.06 TRUE 735.1 Flat foot Both 2 14 14 musculoskeletal darkolivegreen 14, 2 4, 1 3, 0 3, 0 4, 1 -0.404 1.39 0.771 0.113 0.668 0.0142 7.76 -0.128 49.6 0.998 0.001 0.879 0.0551 1.68 -0.0491 65.6 0.999 0 0.952 0.387 0.983 0.59 389 0.999 0.001 1.8 1.39 10.9 PRS_PLINK_1e.06 TRUE 735.2 Acquired toe deformities Both 3 25 14 musculoskeletal darkolivegreen 25, 3 7, 2 6, 0 6, 0 6, 0 -0.602 0.677 0.374 0.427 0.548 0.0945 1.78 -0.716 1.74 0.681 0.167 0.488 0.0103 15.2 -0.0873 1150 1 0 0.916 0.371 1.34 0.239 2.88 0.934 0.03 1.27 0.00441 1390 PRS_PLINK_1e.06 TRUE 735.21 Hammer toe (acquired) Both 3 21 14 musculoskeletal darkolivegreen 21, 3 6, 1 5, 1 5, 0 5, 0 -0.522 0.718 0.468 0.33 0.594 0.052 1.76 -0.868 2.42 0.72 0.143 0.42 0.00738 4040 0.0173 142 1 0 1.02 0.542 3.49 -0.2 6.61 0.976 0.011 0.819 1.47e-05 849000 PRS_PLINK_1e.06 TRUE 735.23 Hallux rigidus Both 0 8 14 musculoskeletal darkolivegreen 8, 0 2 2 2 2 PRS_PLINK_1e.06 TRUE 735.3 Hallux valgus (Bunion) Both 6 26 14 musculoskeletal darkolivegreen 26, 6 7, 2 6, 3 6, 0 7, 0 -1.85 1.04 0.0743 1.129 0.158 0.00225 1.05 1.26 2.02 0.533 0.274 3.52 0.0269 364 -1.04 3.12 0.739 0.132 0.353 0.000184 156 -0.83 1.61 0.606 0.218 0.436 0.009 9.37 PRS_PLINK_1e.06 TRUE 736 Other acquired deformities of limbs Both 7 34 14 musculoskeletal darkolivegreen 34, 7 9, 3 8, 3 8, 0 9, 1 -1.78 0.995 0.0732 1.135 0.168 0.00483 0.833 0.691 1.67 0.678 0.169 2 0.0147 610 -1.92 1.62 0.237 0.625 0.147 0.00107 3.08 -1.57 1.47 0.284 0.546 0.208 0.00376 2.04 PRS_PLINK_1e.06 TRUE 736.2 Acquired deformities of finger Both 1 5 14 musculoskeletal darkolivegreen 5, 1 2, 0 1, 1 1, 0 1, 0 3.1 3110 0.999 0 22.3 0.000144 1.1e+08 1.58 772 0.998 0.001 4.85 0.00198 26100 PRS_PLINK_1e.06 TRUE 736.4 Genu valgum or varum (acquired) Both 0 1 14 musculoskeletal darkolivegreen 1, 0 PRS_PLINK_1e.06 TRUE 736.6 Unequal leg length (acquired) Both 0 6 14 musculoskeletal darkolivegreen 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE 737 Curvature of spine Both 2 18 14 musculoskeletal darkolivegreen 18, 2 5, 2 4, 0 4, 0 5, 0 -0.95 0.852 0.265 0.577 0.387 0.0477 1.53 0.253 4.77 0.958 0.019 1.29 3.11e-05 17500 -2.15 26.6 0.936 0.029 0.116 0.107 0.127 -2.15 3.39 0.525 0.28 0.116 0.000243 18.6 PRS_PLINK_1e.06 TRUE 737.1 Kyphosis (acquired) Both 1 7 14 musculoskeletal darkolivegreen 7, 1 2, 1 2, 0 1, 0 2, 0 -0.684 528 0.999 0 0.505 0.0158 49 0.125 15300 1 0 1.13 0.0606 1.25 -0.193 2630 1 0 0.824 0.762 2.39 0.0113 88.4 1 0 1.01 0.826 1.1 PRS_PLINK_1e.06 TRUE 737.2 Lordosis (acquired) Both 0 1 14 musculoskeletal darkolivegreen 1, 0 PRS_PLINK_1e.06 TRUE 737.3 Kyphoscoliosis and scoliosis Both 1 13 14 musculoskeletal darkolivegreen 13, 1 4, 1 3, 0 3, 0 3, 0 -1.01 2.08 0.626 0.203 0.363 0.00214 47.6 4.6e-12 13.6 1 0 1 0.275 3.57 3.31e-12 38.3 1 0 1 0.00107 934 -0.0808 1.04e+08 1 0 0.922 6.94e-13 2.86e+13 PRS_PLINK_1e.06 TRUE 738 Other acquired musculoskeletal deformity Both 3 24 14 musculoskeletal darkolivegreen 24, 3 6, 2 6, 0 6, 1 6, 0 -1.09 0.814 0.181 0.742 0.337 0.00977 1.75 0.0399 4.4 0.993 0.003 1.04 0.000475 19600000 -1.62 1.72 0.345 0.462 0.197 0.00608 5.32 -1.16 1.99 0.561 0.251 0.314 0.00537 12.1 PRS_PLINK_1e.06 TRUE 738.4 Acquired spondylolisthesis Both 0 12 14 musculoskeletal darkolivegreen 12, 0 3 3 3 3 PRS_PLINK_1e.06 TRUE 739 Contracture of joint Both 2 10 14 musculoskeletal darkolivegreen 10, 2 3, 1 2, 0 2, 0 3, 1 -0.883 2.81 0.753 0.123 0.413 0.000344 124 -0.156 7060 1 0 0.855 0.719 11.7 -1.69 7540 1 0 0.184 2.03e-06 1160000 1.57 30200000 1 0 4.81 0.000834 260 PRS_PLINK_1e.06 TRUE 740 Osteoarthrosis Both 23 40 14 musculoskeletal darkolivegreen 40, 23 10, 5 10, 6 10, 6 10, 5 0.187 0.307 0.543 0.266 1.21 0.69 2.17 0.38 1.11 0.731 0.136 1.46 0.218 11.1 0.157 0.952 0.869 0.061 1.17 0.211 6.64 0.715 0.979 0.465 0.332 2.04 0.367 13.2 PRS_PLINK_1e.06 TRUE 740.1 Osteoarthritis; localized Both 12 30 14 musculoskeletal darkolivegreen 30, 12 8, 2 7, 2 7, 4 8, 4 0.245 0.399 0.54 0.268 1.28 0.629 2.89 0.354 2.24 0.874 0.058 1.43 0.00321 122 3.57 2.43 0.143 0.845 35.4 0.75 31300 0.877 1.15 0.448 0.349 2.4 0.36 22.1 PRS_PLINK_1e.06 TRUE 740.11 Osteoarthrosis, localized, primary Both 9 29 14 musculoskeletal darkolivegreen 29, 9 8, 0 7, 2 7, 3 7, 4 9.56 5.01 0.0563 1.25 14200 2.96 1.8e+14 -0.157 2.2 0.943 0.025 0.855 0.0013 80.2 0.78 1.75 0.656 0.183 2.18 0.00777 112 2.16 1.58 0.172 0.764 8.65 0.718 1960 PRS_PLINK_1e.06 TRUE 740.12 Osteoarthrosis, localized, secondary Both 1 3 14 musculoskeletal darkolivegreen 3, 1 1, 0 1, 0 0, 1 1, 0 0.0174 6680 1 0 1.02 0.587 1.3 -0.00356 90.6 1 0 0.996 0.936 1.16 PRS_PLINK_1e.06 TRUE 740.2 Osteoarthrosis, generalized Both 4 10 14 musculoskeletal darkolivegreen 10, 4 3, 1 2, 0 2, 1 3, 2 0.52 1.39 0.707 0.15 1.68 0.208 55.5 0.0629 490 1 0 1.06 0.762 2.01 -0.0161 1220 1 0 0.984 0.675 1.93 1.26 48.2 0.979 0.009 3.53 1.51e-10 9.55e+10 PRS_PLINK_1e.06 TRUE 740.3 Osteoarthrosis involving more than one site, but not specified as generalized Both 2 1 14 musculoskeletal darkolivegreen 1, 2 -0.205 9860 1 0 0.814 0.652 7.49 PRS_PLINK_1e.06 TRUE 740.9 Osteoarthrosis NOS Both 23 40 14 musculoskeletal darkolivegreen 40, 23 10, 5 10, 6 10, 6 10, 5 0.187 0.307 0.543 0.266 1.21 0.69 2.17 0.38 1.11 0.731 0.136 1.46 0.218 11.1 0.157 0.952 0.869 0.061 1.17 0.211 6.64 0.715 0.979 0.465 0.332 2.04 0.367 13.2 PRS_PLINK_1e.06 TRUE 741 Symptoms and disorders of the joints Both 15 46 14 musculoskeletal darkolivegreen 46, 15 11, 5 11, 5 11, 3 12, 2 -0.102 0.304 0.738 0.132 0.903 0.517 1.6 0.225 1.06 0.831 0.08 1.25 0.202 8.99 -0.392 0.947 0.679 0.168 0.676 0.111 3.67 -1.02 1.19 0.395 0.404 0.362 0.0172 3 PRS_PLINK_1e.06 TRUE 741.1 Ankylosis of joint Both 1 3 14 musculoskeletal darkolivegreen 3, 1 1, 1 1, 0 1, 0 1, 1 -0.014 1450 1 0 0.986 0.77 1.58 -0.0312 261 1 0 0.969 0.858 1.17 -0.0117 69.2 1 0 0.988 0.872 1.05 PRS_PLINK_1e.06 TRUE 741.2 Stiffness of joint Both 2 17 14 musculoskeletal darkolivegreen 17, 2 5, 1 4, 1 4, 0 4, 0 -0.512 0.978 0.601 0.221 0.599 0.0449 7.93 2.91 67.7 0.966 0.015 18.3 15.8 21.3 1.04 5.8 0.858 0.066 2.82 0.000468 15800 -0.367 11.6 0.975 0.011 0.693 7.6e-07 1300000 PRS_PLINK_1e.06 TRUE 741.3 Difficulty in walking Both 1 23 14 musculoskeletal darkolivegreen 23, 1 6, 1 6, 0 5, 0 6, 0 -0.342 0.873 0.695 0.158 0.71 0.0587 7.92 -0.788 2.85 0.782 0.107 0.455 0.00552 6300 -0.57 2.14 0.79 0.102 0.566 0.0225 69.9 -0.0349 2.56 0.989 0.005 0.966 0.0253 863 PRS_PLINK_1e.06 TRUE 741.4 Joint effusions Both 9 32 14 musculoskeletal darkolivegreen 32, 9 8, 4 8, 2 8, 2 8, 1 -0.0874 0.457 0.848 0.071 0.916 0.379 2.06 -0.344 1.86 0.854 0.069 0.709 0.00978 79.8 -0.27 1.64 0.869 0.061 0.763 2.82e-07 63.9 -0.485 1.43 0.735 0.133 0.616 0.036 7.45 PRS_PLINK_1e.06 TRUE 741.5 Hemarthrosis Both 1 2 14 musculoskeletal darkolivegreen 2, 1 1, 1 1, 0 1, 1 1, 0 -0.00897 36.4 1 0 0.991 0.946 1.05 0.0208 80.7 1 0 1.02 0.866 1.07 PRS_PLINK_1e.06 TRUE 741.6 Villonodular synovitis Both 1 1 14 musculoskeletal darkolivegreen 1, 1 0.000165 34.2 1 0 1 0.998 1 PRS_PLINK_1e.06 TRUE 742 Derangement of joint, non-traumatic Both 7 45 14 musculoskeletal darkolivegreen 45, 7 11, 1 11, 3 11, 2 11, 1 0.214 0.42 0.61 0.215 1.24 0.571 3.31 2.79 1.88 0.139 0.857 16.3 0.907 683 0.383 1.06 0.718 0.144 1.47 0.145 11.1 0.208 1.46 0.887 0.052 1.23 0.0244 699 PRS_PLINK_1e.06 TRUE 742.1 Loose body in joint Both 1 3 14 musculoskeletal darkolivegreen 3, 1 1, 0 1, 0 1, 1 1, 0 0.00113 1690 1 0 1 0.427 5.05 -0.00311 14.1 1 0 0.997 0.969 1.03 PRS_PLINK_1e.06 TRUE 742.2 Pathological, developmental or recurrent dislocation Both 0 3 14 musculoskeletal darkolivegreen 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 742.8 Articular cartilage disorder Both 1 5 14 musculoskeletal darkolivegreen 5, 1 2, 1 1, 0 1, 0 1, 0 -0.161 301 1 0 0.851 0.394 2.07 1.72 15000 1 0 5.58 0.0149 51.8 0.11 1250 1 0 1.12 0.769 1.96 0.282 15100 1 0 1.33 0.418 3.09 PRS_PLINK_1e.06 TRUE 742.9 Other derangement of joint Both 5 43 14 musculoskeletal darkolivegreen 43, 5 10, 0 11, 3 10, 2 11, 0 0.516 0.618 0.404 0.394 1.68 0.526 15.3 0.642 1.68 0.703 0.153 1.9 0.044 2320 1.15 1.28 0.368 0.434 3.16 0.369 109 PRS_PLINK_1e.06 TRUE 743 Osteoporosis, osteopenia and pathological fracture Both 12 51 14 musculoskeletal darkolivegreen 51, 12 12, 4 13, 3 12, 4 13, 1 -0.15 0.385 0.697 0.157 0.861 0.398 1.91 1.23 1.36 0.367 0.435 3.42 0.319 804 -0.454 1.14 0.689 0.162 0.635 0.00463 18.2 -0.0406 1.06 0.97 0.013 0.96 0.106 8.19 PRS_PLINK_1e.06 TRUE 743.1 Osteoporosis Both 6 22 14 musculoskeletal darkolivegreen 22, 6 6, 2 5, 2 5, 1 6, 1 0.269 0.676 0.691 0.16 1.31 0.469 19.6 -0.0269 2.88 0.993 0.003 0.973 7.14e-05 516 0.332 8.66 0.969 0.014 1.39 0.028 34300000 0.867 1.95 0.657 0.182 2.38 0.057 256000 PRS_PLINK_1e.06 TRUE 743.11 Osteoporosis NOS Both 6 21 14 musculoskeletal darkolivegreen 21, 6 6, 2 5, 2 5, 1 5, 1 0.269 0.676 0.691 0.16 1.31 0.469 19.6 0.353 2.63 0.893 0.049 1.42 0.00579 1060 0.814 3.02 0.787 0.104 2.26 6.13e-08 1710 1.08 2.03 0.593 0.227 2.96 0.0835 143000 PRS_PLINK_1e.06 TRUE 743.12 Senile osteoporosis Both 0 4 14 musculoskeletal darkolivegreen 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 743.13 Other specified osteoporosis Both 3 4 14 musculoskeletal darkolivegreen 4, 3 1, 1 1, 0 1, 1 1, 1 0.114 188 1 0 1.12 0.171 6.66 -0.0041 31.3 1 0 0.996 0.976 1.07 -0.186 5400 1 0 0.83 0.648 1.55 4.42 20600 1 0 82.8 6.88e-05 39400000 PRS_PLINK_1e.06 TRUE 743.2 Pathologic fracture Both 2 8 14 musculoskeletal darkolivegreen 8, 2 2, 1 2, 0 2, 0 2, 1 -13 151 0.932 0.031 2.33e-06 1.02e-06 5.36e-06 0.079 1040 1 0 1.08 1.51e-09 1.4e+13 0.123 7120 1 0 1.13 0.563 4.76 0.0588 1910 1 0 1.06 0.0318 4.35 PRS_PLINK_1e.06 TRUE 743.21 Pathologic fracture of vertebrae Both 1 4 14 musculoskeletal darkolivegreen 4, 1 1, 1 1, 0 1, 0 1, 0 0.000856 260 1 0 1 0.244 3.82 0.00212 10.9 1 0 1 0.92 1.04 0.000403 38.3 1 0 1 0.987 1.01 0.00743 8.96 0.999 0 1.01 0.563 1.04 PRS_PLINK_1e.06 TRUE 743.22 Pathologic fracture of femur Both 0 1 14 musculoskeletal darkolivegreen 1, 0 PRS_PLINK_1e.06 TRUE 743.4 Stress fracture Both 2 6 14 musculoskeletal darkolivegreen 6, 2 2, 0 1, 0 1, 1 2, 1 0.0536 374 1 0 1.06 0.811 1.79 -0.0117 55.3 1 0 0.988 0.928 1.06 0.254 2390 1 0 1.29 0.375 1.57 PRS_PLINK_1e.06 TRUE 743.9 Osteopenia or other disorder of bone and cartilage Both 9 46 14 musculoskeletal darkolivegreen 46, 9 11, 3 11, 3 11, 2 12, 1 -0.157 0.388 0.686 0.164 0.855 0.408 1.86 1.07 1.47 0.467 0.33 2.91 0.0859 485 0.00914 1.22 0.994 0.003 1.01 0.0993 29.9 -0.29 1.18 0.806 0.094 0.748 0.0096 7.04 PRS_PLINK_1e.06 TRUE 745 Pain in joint Both 42 22 14 musculoskeletal darkolivegreen 22, 42 5, 8 5, 14 5, 9 6, 11 -0.0505 0.309 0.87 0.06 0.951 0.531 1.7 0.0296 1.07 0.978 0.01 1.03 0.162 7.18 0.128 1.29 0.921 0.036 1.14 0.075 76.5 0.284 0.997 0.776 0.11 1.33 0.214 8.82 PRS_PLINK_1e.06 TRUE 747 Cardiac and circulatory congenital anomalies Both 3 23 15 congenital anomalies mediumspringgreen 23, 3 5, 1 6, 0 5, 0 6, 2 0.232 0.675 0.731 0.136 1.26 0.405 9.34 -1.35 8.48 0.874 0.059 0.26 7.4e-07 169000 1.22 67.9 0.986 0.006 3.4 3.16 3.66 1.32 2.24 0.556 0.255 3.75 0.177 55.1 PRS_PLINK_1e.06 TRUE 747.1 Cardiac congenital anomalies Both 3 17 15 congenital anomalies mediumspringgreen 17, 3 4, 1 4, 0 4, 0 4, 2 0.647 0.799 0.418 0.379 1.91 0.545 64.5 10.5 473 0.982 0.008 35000 380000 5.63e+18 -2.41 186 0.99 0.005 0.0897 8.55e-06 15.5 2.3 3.13 0.463 0.334 9.96 0.351 11.6 PRS_PLINK_1e.06 TRUE 747.11 Cardiac shunt/ heart septal defect Both 1 9 15 congenital anomalies mediumspringgreen 9, 1 3, 0 2, 0 2, 0 2, 1 -0.159 2.77 0.954 0.02 0.853 0.00617 71.3 -0.188 767 1 0 0.828 0.36 1.3 PRS_PLINK_1e.06 TRUE 747.12 Valvular heart disease/ heart chambers Both 2 4 15 congenital anomalies mediumspringgreen 4, 2 1, 0 1, 0 1, 0 1, 2 0.0178 12400000 1 0 1.02 0.469 1.79 -17.4 37300 1 0 2.86e-08 2.05e-30 9.4e+07 PRS_PLINK_1e.06 TRUE 747.13 Congenital anomalies of great vessels Both 0 3 15 congenital anomalies mediumspringgreen 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 747.2 Congenital anomalies of peripheral vascular system Both 0 7 15 congenital anomalies mediumspringgreen 7, 0 2 2 1 2 PRS_PLINK_1e.06 TRUE 748 Anomalies of respiratory system, congenital Both 0 3 15 congenital anomalies mediumspringgreen 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 749 Congenital anomalies of face and neck Both 2 12 15 congenital anomalies mediumspringgreen 12, 2 3, 1 3, 0 3, 1 3, 0 -0.0356 0.813 0.965 0.015 0.965 0.0813 3.82 -0.0388 203 1 0 0.962 0.547 1.49 -0.0263 445 1 0 0.974 0.4 5.02 0.464 1430 1 0 1.59 0.357 4.1 PRS_PLINK_1e.06 TRUE 749.1 Cleft palate Both 0 2 15 congenital anomalies mediumspringgreen 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 749.2 Congenital anomalies of skull and face bones Both 0 2 15 congenital anomalies mediumspringgreen 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 750 Digestive congenital anomalies Both 2 13 15 congenital anomalies mediumspringgreen 13, 2 4, 0 3, 0 3, 2 3, 0 2.38 3.89 0.54 0.267 10.8 0.0198 12600 0.257 3210 1 0 1.29 0.0769 32.8 PRS_PLINK_1e.06 TRUE 750.1 Upper gastrointestinal congenital anomalies Both 0 4 15 congenital anomalies mediumspringgreen 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 750.11 Esophageal atresia/tracheoesophageal fistula Both 0 2 15 congenital anomalies mediumspringgreen 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 750.13 Congenital anomalies of mouth/tongue Both 0 2 15 congenital anomalies mediumspringgreen 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 750.14 Congenital anomalies of esophagus Both 0 1 15 congenital anomalies mediumspringgreen 1, 0 PRS_PLINK_1e.06 TRUE 750.2 Lower gastrointestinal congenital anomalies Both 2 11 15 congenital anomalies mediumspringgreen 11, 2 2, 0 3, 0 2, 2 3, 0 2.57 5.41 0.634 0.198 13.1 11 15.6 -0.0072 48.7 1 0 0.993 0.929 1.04 PRS_PLINK_1e.06 TRUE 750.21 Congenital anomalies of intestine Both 1 6 15 congenital anomalies mediumspringgreen 6, 1 1, 0 1, 0 1, 1 2, 0 -1.44 2690 1 0 0.237 1.47e-16 6.34e+09 -0.00216 159 1 0 0.998 0.963 1.04 PRS_PLINK_1e.06 TRUE 750.22 Congenital anomaly of gallbladder, bile ducts, liver, pancreas Both 1 9 15 congenital anomalies mediumspringgreen 9, 1 2, 0 2, 0 2, 1 2, 0 0.579 10.2 0.955 0.02 1.78 0.000769 5590 -0.0128 1120 1 0 0.987 0.744 1.77 PRS_PLINK_1e.06 TRUE 751 Genitourinary congenital anomalies Both 8 28 15 congenital anomalies mediumspringgreen 28, 8 6, 0 7, 6 7, 1 7, 1 0.154 0.451 0.733 0.135 1.17 0.537 2.98 1.44 1.93 0.455 0.342 4.22 0.231 6830 0.556 1.93 0.774 0.111 1.74 0.027 17800 -0.508 2.14 0.812 0.09 0.601 0.00425 19.7 PRS_PLINK_1e.06 TRUE 751.1 Congenital anomalies of genital organs Both 3 5 15 congenital anomalies mediumspringgreen 5, 3 2, 2 1, 1 1, 0 1, 0 0.116 184 0.999 0 1.12 0.664 4.01 0.414 1000 1 0 1.51 0.666 1.93 -0.374 4790 1 0 0.688 0.00689 14.8 0.333 4410 1 0 1.39 0.065 307 PRS_PLINK_1e.06 TRUE 751.11 Congenital anomalies of female genital organs Female 2 3 15 congenital anomalies mediumspringgreen 3, 2 1, 1 1, 1 1, 0 1, 1 -0.00627 505 1 0 0.994 0.626 1.26 -0.0273 168 1 0 0.973 0.714 1.17 -0.489 2780 1 0 0.613 0.0434 2.43 PRS_PLINK_1e.06 TRUE 751.12 Congenital anomalies of male genital organs Male 0 4 15 congenital anomalies mediumspringgreen 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 751.2 Congenital anomalies of urinary system Both 6 7 15 congenital anomalies mediumspringgreen 7, 6 1, 0 2, 4 1, 0 2, 2 -0.537 1.68 0.749 0.126 0.584 0.0061 12.5 1.44 1590 0.999 0 4.23 2.77e-07 109 -0.387 50400 1 0 0.679 0.278 4.64 PRS_PLINK_1e.06 TRUE 751.21 Cystic kidney disease Both 2 4 15 congenital anomalies mediumspringgreen 4, 2 1, 2 1, 0 1, 0 1, 0 -0.0254 1170 1 0 0.975 0.604 1.52 -2.25 3.15e+08 1 0 0.105 0.000127 505 17.7 140000 1 0 51100000 2.59e-21 8.38e+35 -21 167000 1 0 7.49e-10 6.55e-48 5.71e+25 PRS_PLINK_1e.06 TRUE 751.22 Other specified congenital anomalies of kidney Both 5 3 15 congenital anomalies mediumspringgreen 3, 5 1, 1 1, 0 0, 2 1, 2 0.0352 213 1 0 1.04 0.923 1.68 0.00461 19.9 1 0 1 0.917 1.1 -0.00118 14.6 1 0 0.999 0.964 1.02 -0.03 1070 1 0 0.97 0.254 2.2 PRS_PLINK_1e.06 TRUE 751.3 Obstructive genitourinary defect Both 1 4 15 congenital anomalies mediumspringgreen 4, 1 1, 0 1, 0 1, 0 1, 1 0.000769 9390 1 0 1 0.0842 44.7 0.00552 55.7 1 0 1.01 0.944 1.09 PRS_PLINK_1e.06 TRUE 752 Nervous system congenital anomalies Both 1 15 15 congenital anomalies mediumspringgreen 15, 1 4, 0 4, 0 3, 1 4, 0 0.599 1.98 0.762 0.118 1.82 0.00327 170000 4.09 1250 0.997 0.001 59.8 1.18 7310000 PRS_PLINK_1e.06 TRUE 752.1 Neural tube defects Both 0 13 15 congenital anomalies mediumspringgreen 13, 0 4 3 3 3 PRS_PLINK_1e.06 TRUE 752.11 Spina bifida Both 0 2 15 congenital anomalies mediumspringgreen 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 752.2 Other specified congenital anomalies of nervous system Both 0 4 15 congenital anomalies mediumspringgreen 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 753 Congenital anomalies of the eye Both 1 8 15 congenital anomalies mediumspringgreen 8, 1 2, 0 2, 0 2, 1 2, 0 3.57 72.3 0.961 0.017 35.4 0.0937 12600 0.0229 7650 1 0 1.02 0.205 1.81 PRS_PLINK_1e.06 TRUE 753.1 Congenital cataract and lens anomalies Both 0 1 15 congenital anomalies mediumspringgreen 1, 0 PRS_PLINK_1e.06 TRUE 753.2 Congenital anomalies of posterior segment of eye Both 0 3 15 congenital anomalies mediumspringgreen 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 754 Congenital musculoskeletal deformities of spine Both 1 11 15 congenital anomalies mediumspringgreen 11, 1 3, 0 3, 1 2, 0 3, 0 -2.09 2.82 0.457 0.34 0.123 2.06e-05 5.46 -0.744 334 0.998 0.001 0.475 0.0177 11 PRS_PLINK_1e.06 TRUE 754.1 Lumbosacral spondylolysis, congenital Both 1 2 15 congenital anomalies mediumspringgreen 2, 1 1, 1 1, 0 1, 1 1, 0 0.0122 34.8 1 0 1.01 0.898 1.07 0.00967 66.7 1 0 1.01 0.978 1.05 PRS_PLINK_1e.06 TRUE 754.2 Spondylolisthesis, congenital Both 0 5 15 congenital anomalies mediumspringgreen 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 755 Congenital anomalies of limbs Both 1 14 15 congenital anomalies mediumspringgreen 14, 1 4, 0 3, 1 3, 0 4, 0 -0.404 0.955 0.672 0.172 0.668 0.0774 4.33 -0.0208 27.1 0.999 0 0.979 0.854 2.78 PRS_PLINK_1e.06 TRUE 755.1 Congenital deformities of feet Both 1 9 15 congenital anomalies mediumspringgreen 9, 1 3, 0 2, 0 2, 1 2, 0 2.18e-13 6.47 1 0 1 0.00418 205 0.128 1250 1 0 1.14 0.183 4.25 PRS_PLINK_1e.06 TRUE 755.6 Other congenital anomalies of lower limb, including pelvic girdle Both 0 4 15 congenital anomalies mediumspringgreen 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 755.61 Congenital hip dysplasia and deformity Both 0 2 15 congenital anomalies mediumspringgreen 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 756 Other congenital musculoskeletal anomalies Both 2 17 15 congenital anomalies mediumspringgreen 17, 2 4, 1 4, 1 4, 0 4, 0 0.105 0.698 0.881 0.055 1.11 0.176 4.52 -0.228 3.64 0.95 0.022 0.796 0.000955 108 0.0392 723 1 0 1.04 0.764 1.31 -0.232 43.9 0.996 0.002 0.793 0.00213 279 PRS_PLINK_1e.06 TRUE 756.2 Pectus and other congenital anomalies of ribs/sternum Both 0 1 15 congenital anomalies mediumspringgreen 1, 0 PRS_PLINK_1e.06 TRUE 756.3 Congenital anomalies of muscle, tendon, fascia, and connective tissue Both 0 2 15 congenital anomalies mediumspringgreen 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 756.5 Congenital osteodystrophies Both 1 11 15 congenital anomalies mediumspringgreen 11, 1 2, 1 3, 0 2, 0 3, 0 -0.269 2.36 0.909 0.041 0.764 0.0173 120 -0.249 12600 1 0 0.78 0.693 3.45 -21.1 12700 0.999 0.001 7.17e-10 3.09e-46 3.38e+29 -0.0655 1640 1 0 0.937 0.722 2.88 PRS_PLINK_1e.06 TRUE 757 Congenital anomalies of the integument Both 1 4 15 congenital anomalies mediumspringgreen 4, 1 1, 0 1, 0 1, 0 1, 0 -2 2340 0.999 0 0.135 3.4e-05 4530 PRS_PLINK_1e.06 TRUE 758 Chromosomal anomalies and genetic disorders Both 1 2 15 congenital anomalies mediumspringgreen 2, 1 1, 0 1, 1 1, 0 1, 1 -0.423 37500 1 0 0.655 0.316 27.2 -0.204 14000 1 0 0.815 0.515 2 PRS_PLINK_1e.06 TRUE 758.1 Chromosomal anomalies Both 1 0 15 congenital anomalies mediumspringgreen 0, 1 PRS_PLINK_1e.06 TRUE 759 Other and unspecified congenital anomalies Both 0 3 15 congenital anomalies mediumspringgreen 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 760 Back pain Both 25 39 17 symptoms purple 39, 25 9, 3 10, 7 9, 11 10, 4 0.218 0.286 0.445 0.352 1.24 0.75 2.16 1.84 2.02 0.362 0.441 6.31 0.256 553 1.15 0.937 0.218 0.661 3.17 0.672 18.3 0.389 1.03 0.707 0.151 1.48 0.236 10.3 PRS_PLINK_1e.06 TRUE 761 Cervicalgia Both 15 48 17 symptoms purple 48, 15 11, 4 12, 5 12, 4 12, 2 -0.12 0.32 0.708 0.15 0.887 0.487 1.65 -0.945 1.64 0.565 0.248 0.389 2.1e-07 11.4 0.00378 0.905 0.997 0.001 1 0.19 5.15 -0.588 1.09 0.59 0.229 0.555 0.062 4.02 PRS_PLINK_1e.06 TRUE 763 Thoracic or lumbosacral neuritis or radiculitis, unspecified Both 2 39 17 symptoms purple 39, 2 9, 0 10, 1 9, 1 10, 0 0.252 0.583 0.666 0.177 1.29 0.402 10.9 0.299 1.56 0.848 0.072 1.35 0.0662 41 0.632 1.67 0.705 0.152 1.88 0.0406 63.5 PRS_PLINK_1e.06 TRUE 764 Sciatica Both 2 38 17 symptoms purple 38, 2 9, 0 9, 0 9, 2 10, 0 0.0126 0.569 0.982 0.008 1.01 0.151 7.07 0.221 1.55 0.886 0.052 1.25 0.0148 31.2 PRS_PLINK_1e.06 TRUE 765 Cervical radiculitis Both 3 25 17 symptoms purple 25, 3 6, 0 6, 1 6, 2 6, 0 -0.108 0.562 0.848 0.071 0.898 0.256 3.42 0.0651 2.29 0.977 0.01 1.07 0.0143 106 0.537 2.42 0.824 0.084 1.71 0.00053 1330 PRS_PLINK_1e.06 TRUE 766 Neuralgia, neuritis, and radiculitis NOS Both 6 48 17 symptoms purple 48, 6 11, 0 12, 3 12, 2 12, 1 0.0618 0.402 0.878 0.057 1.06 0.474 2.53 0.775 1.87 0.678 0.169 2.17 0.0389 1620 0.179 1.76 0.919 0.037 1.2 0.00126 65.3 0.964 1.46 0.508 0.294 2.62 0.113 620 PRS_PLINK_1e.06 TRUE 767 Cervicocranial/Cervicobrachial syndrome Both 0 1 17 symptoms purple 1, 0 PRS_PLINK_1e.06 TRUE 769 Nonallopathic lesions NEC Both 2 20 17 symptoms purple 20, 2 5, 2 5, 0 5, 0 5, 0 -0.689 1.1 0.53 0.275 0.502 0.00936 3.44 0.0434 1380 1 0 1.04 0.667 2.31 0.157 12.7 0.99 0.004 1.17 2.53e-05 17700 -1.2 5.72 0.834 0.079 0.301 0.285 0.317 PRS_PLINK_1e.06 TRUE 770 Myalgia and myositis unspecified Both 11 47 17 symptoms purple 47, 11 11, 4 12, 2 11, 3 12, 2 0.162 0.407 0.691 0.16 1.18 0.552 2.86 -0.107 1.32 0.935 0.029 0.898 0.0199 29.6 -0.45 1.11 0.686 0.164 0.637 0.0528 5.37 -0.0334 1.02 0.974 0.011 0.967 0.144 7.68 PRS_PLINK_1e.06 TRUE 771 Musculoskeletal symptoms referable to limbs Both 6 44 17 symptoms purple 44, 6 10, 1 11, 2 11, 3 11, 0 -0.179 0.596 0.765 0.117 0.836 0.137 3.37 -0.43 2.37 0.856 0.067 0.651 0.00481 2490 0.294 1.43 0.836 0.078 1.34 0.0655 19.8 0.0779 1.46 0.958 0.019 1.08 0.0348 39.4 PRS_PLINK_1e.06 TRUE 771.1 Swelling of limb Both 11 43 17 symptoms purple 43, 11 10, 2 11, 5 10, 2 11, 2 -0.161 0.362 0.657 0.182 0.851 0.43 1.71 -0.302 1.24 0.807 0.093 0.739 0.0639 8.03 -1.17 1.81 0.518 0.286 0.31 0.000219 13.3 0.348 1.32 0.792 0.101 1.42 0.0446 25.1 PRS_PLINK_1e.06 TRUE 771.2 Cramp of limb Both 1 18 17 symptoms purple 18, 1 5, 0 4, 0 4, 1 5, 0 0.0693 1.1 0.95 0.022 1.07 0.0996 51.8 -0.774 8.74 0.929 0.032 0.461 1.75e-06 667000 PRS_PLINK_1e.06 TRUE 772 Symptoms of the muscles Both 6 23 17 symptoms purple 23, 6 5, 2 6, 2 5, 2 6, 0 -0.289 0.685 0.673 0.172 0.749 0.0744 2.89 0.213 1.72 0.901 0.045 1.24 0.0292 1.42 0.242 1.68 0.885 0.053 1.27 1.15 1.85 -2.29 6.14 0.709 0.149 0.102 2.7e-06 1720 PRS_PLINK_1e.06 TRUE 772.1 Muscular wasting and disuse atrophy Both 1 9 17 symptoms purple 9, 1 3, 0 2, 0 2, 1 2, 0 0.365 2.69 0.892 0.05 1.44 0.0352 101 -0.164 1620000 1 0 0.848 0.0921 7.83 PRS_PLINK_1e.06 TRUE 772.2 Spasm of muscle Both 3 31 17 symptoms purple 31, 3 7, 1 8, 1 7, 1 8, 0 -0.149 0.579 0.797 0.099 0.861 0.16 4.45 0.57 2.17 0.793 0.101 1.77 0.0246 313 -0.213 1.51 0.888 0.052 0.808 0.0018 18.5 -0.481 1.57 0.759 0.12 0.618 0.00108 19.9 PRS_PLINK_1e.06 TRUE 772.3 Muscle weakness Both 4 27 17 symptoms purple 27, 4 7, 1 7, 0 6, 3 7, 0 0.00725 0.784 0.993 0.003 1.01 0.14 18.4 0.0297 2.46 0.99 0.004 1.03 0.0184 720000 1.21 1.95 0.536 0.271 3.34 0.169 2160 -0.453 2.67 0.865 0.063 0.635 4.48e-05 669 PRS_PLINK_1e.06 TRUE 772.4 Rhabdomyolysis Both 2 0 17 symptoms purple 0, 2 PRS_PLINK_1e.06 TRUE 772.6 Facial weakness Both 0 3 17 symptoms purple 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 780 Hypothermia/Chills Both 1 8 17 symptoms purple 8, 1 2, 1 2, 0 2, 0 2, 0 9.89 104 0.925 0.034 19700 14700 54500 0.0449 2570 1 0 1.05 0.445 2.56 0.0846 6130 1 0 1.09 0.226 26.1 0.156 9290 1 0 1.17 0.0882 1.27 PRS_PLINK_1e.06 TRUE 781 Symptoms involving nervous and musculoskeletal systems Both 4 31 17 symptoms purple 31, 4 8, 1 8, 2 7, 1 8, 0 -0.167 0.864 0.847 0.072 0.846 0.0777 61.4 0.336 1.61 0.834 0.079 1.4 0.0429 224 0.0692 1.95 0.972 0.012 1.07 0.00388 550 0.438 1.71 0.798 0.098 1.55 0.0142 86.6 PRS_PLINK_1e.06 TRUE 782.3 Edema Both 12 40 17 symptoms purple 40, 12 9, 1 10, 4 10, 5 10, 2 -0.043 0.361 0.905 0.043 0.958 0.487 1.94 -0.767 1.87 0.681 0.167 0.464 0.0117 65.3 0.0722 1.22 0.953 0.021 1.07 0.128 10.2 0.0333 1.46 0.982 0.008 1.03 0.0424 22.2 PRS_PLINK_1e.06 TRUE 782.6 Pallor and flushing Both 2 10 17 symptoms purple 10, 2 3, 0 2, 0 2, 1 3, 1 -0.652 3.37 0.847 0.072 0.521 3.24e-05 739 0.399 2610 1 0 1.49 0.388 2.56 -0.319 3490 1 0 0.727 0.104 3.69 PRS_PLINK_1e.06 TRUE 783 Fever of unknown origin Both 10 52 17 symptoms purple 52, 10 12, 3 13, 1 13, 5 13, 1 0.174 0.349 0.617 0.21 1.19 0.633 2.53 0.212 1.55 0.891 0.05 1.24 0.067 4550 0.331 0.877 0.706 0.151 1.39 0.306 7.02 0.277 1.23 0.822 0.085 1.32 0.0531 22.4 PRS_PLINK_1e.06 TRUE 785 Abdominal pain Both 30 34 17 symptoms purple 34, 30 8, 6 8, 12 8, 8 9, 4 -0.0259 0.277 0.925 0.034 0.974 0.582 1.61 0.949 1 0.342 0.466 2.58 0.478 16.5 0.0616 0.9 0.945 0.024 1.06 0.199 5.36 -0.343 0.973 0.724 0.14 0.71 0.112 3.75 PRS_PLINK_1e.06 TRUE 788 Syncope and collapse Both 5 49 17 symptoms purple 49, 5 12, 0 12, 2 12, 1 12, 2 0.262 0.479 0.584 0.234 1.3 0.53 4.14 0.922 1.89 0.626 0.203 2.51 0.048 65800000 0.633 1.65 0.701 0.154 1.88 0.0295 662 1.08 1.42 0.447 0.349 2.93 0.198 49500 PRS_PLINK_1e.06 TRUE 789 Nausea and vomiting Both 18 46 17 symptoms purple 46, 18 11, 2 11, 6 11, 7 12, 3 0.0179 0.292 0.951 0.022 1.02 0.597 1.77 2.55 1.89 0.177 0.751 12.8 0.261 16.6 0.774 1.03 0.451 0.346 2.17 0.368 20.4 0.556 1.09 0.611 0.214 1.74 0.255 17.1 PRS_PLINK_1e.06 TRUE 789.1 Persistent vomiting Both 2 10 17 symptoms purple 10, 2 2, 1 2, 1 2, 0 3, 0 -0.206 2.12 0.923 0.035 0.814 0.0204 36.8 -0.819 3910 1 0 0.441 0.284 2.19 10.9 11500 0.999 0 56300 3.85e-41 2.12e+51 -0.0229 679 1 0 0.977 0.694 1.34 PRS_PLINK_1e.06 TRUE 790 Nonspecific findings on examination of blood Both 16 27 17 symptoms purple 27, 16 6, 2 7, 2 6, 8 7, 4 0.0915 0.519 0.86 0.066 1.1 0.237 3.13 0.465 3.71 0.9 0.046 1.59 0.000342 52300 1.24 1.3 0.341 0.468 3.46 0.3 110 -0.184 1.43 0.898 0.047 0.832 0.0141 15.9 PRS_PLINK_1e.06 TRUE 790.1 Elevated sedimentation rate Both 1 4 17 symptoms purple 4, 1 1, 0 1, 1 1, 0 1, 0 1.24 2570 1 0 3.45 0.0449 564 -0.00324 35 1 0 0.997 0.95 1.05 PRS_PLINK_1e.06 TRUE 790.6 Other abnormal blood chemistry Both 22 40 17 symptoms purple 40, 22 9, 4 10, 6 10, 8 10, 4 0.337 0.353 0.339 0.469 1.4 0.744 2.91 0.799 1.31 0.541 0.267 2.22 0.253 41.3 0.927 1.07 0.387 0.412 2.53 0.388 27.9 0.0764 1.22 0.95 0.022 1.08 0.0573 22.9 PRS_PLINK_1e.06 TRUE 790.8 Elevated C-reactive protein (CRP) Both 0 5 17 symptoms purple 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 790.9 Abnormal arterial blood gases Both 0 2 17 symptoms purple 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 791 Gangrene Both 0 13 17 symptoms purple 13, 0 4 3 3 3 PRS_PLINK_1e.06 TRUE 792 Abnormal Papanicolaou smear of cervix and cervical HPV Female 6 15 11 genitourinary black 15, 6 3, 3 4, 1 3, 1 4, 1 -0.625 0.721 0.386 0.413 0.535 0.136 1.68 0.166 4.37 0.97 0.013 1.18 0.00076 2250 6.1 24.1 0.801 0.097 444 192 889 -2 4.89 0.683 0.165 0.136 3.88e-06 1560 PRS_PLINK_1e.06 TRUE 792.1 Papanicolaou smear of cervix or vagina with atypical squamous cells Female 4 7 11 genitourinary black 7, 4 1, 1 2, 1 1, 1 2, 1 1.43 1.93 0.458 0.34 4.2 0.262 2240 0.0111 1020 1 0 1.01 0.798 1.33 0.151 2750 1 0 1.16 0.696 4.07 0.0573 4280 1 0 1.06 0.106 7.69 PRS_PLINK_1e.06 TRUE 794 Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc) Both 0 5 17 symptoms purple 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 795 Other and nonspecific abnormal cytological, histological and immunological findings Both 3 27 17 symptoms purple 27, 3 6, 1 7, 0 6, 1 7, 1 -0.198 0.69 0.775 0.111 0.821 0.185 4.67 -0.887 2.25 0.693 0.159 0.412 0.000211 16.8 0.402 2.37 0.865 0.063 1.49 0.341 1.79 -0.576 3.65 0.875 0.058 0.562 0.000165 125000 PRS_PLINK_1e.06 TRUE 795.8 Abnormal tumor markers Both 1 13 17 symptoms purple 13, 1 4, 0 3, 0 3, 1 3, 0 -0.371 0.825 0.653 0.185 0.69 0.117 2.8 -0.354 6180000 1 0 0.702 0.0312 29.5 PRS_PLINK_1e.06 TRUE 795.81 Elevated carcinoembryonic antigen [CEA] Both 0 1 17 symptoms purple 1, 0 PRS_PLINK_1e.06 TRUE 795.82 Elevated cancer antigen 125 [CA 125] Both 0 2 17 symptoms purple 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 796 Elevated prostate specific antigen [PSA] Male 2 10 11 genitourinary black 10, 2 3, 0 2, 1 2, 1 3, 0 -0.243 0.822 0.767 0.115 0.784 0.081 4.03 0.0191 197 1 0 1.02 0.901 1.31 -5.68 606 0.993 0.003 0.00341 1.57e-10 114000 PRS_PLINK_1e.06 TRUE 797 Shock Both 0 10 17 symptoms purple 10, 0 3 2 2 3 PRS_PLINK_1e.06 TRUE 797.1 Cardiogenic shock Both 0 4 17 symptoms purple 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 798 Malaise and fatigue Both 25 39 17 symptoms purple 39, 25 9, 6 10, 7 9, 6 10, 6 0.048 0.31 0.877 0.057 1.05 0.597 1.92 -0.0319 1.19 0.979 0.009 0.969 0.095 9.93 0.26 1.01 0.798 0.098 1.3 0.193 9.71 -0.0334 1.1 0.976 0.011 0.967 0.0844 7.49 PRS_PLINK_1e.06 TRUE 798.1 Chronic fatigue syndrome Both 4 20 17 symptoms purple 20, 4 4, 1 5, 1 5, 1 5, 1 0.0987 0.92 0.915 0.039 1.1 0.141 6.47 0.932 2.39 0.697 0.157 2.54 0.00975 366 0.795 4.07 0.845 0.073 2.21 1.29 2.51 -0.651 3.49 0.852 0.07 0.521 0.00141 169 PRS_PLINK_1e.06 TRUE 800 Fracture of lower limb Both 6 28 18 injuries & poisonings gray50 28, 6 7, 1 7, 0 7, 2 7, 3 0.157 0.482 0.744 0.128 1.17 0.496 3.43 -0.28 3.12 0.929 0.032 0.756 0.00359 2300 0.0215 1.71 0.99 0.004 1.02 0.0887 31.5 0.725 1.36 0.593 0.227 2.06 0.21 262 PRS_PLINK_1e.06 TRUE 800.1 Fracture of neck of femur Both 0 7 18 injuries & poisonings gray50 7, 0 2 2 1 2 PRS_PLINK_1e.06 TRUE 800.2 Fracture of unspecified part of femur Both 2 3 18 injuries & poisonings gray50 3, 2 1, 2 1, 0 1, 0 1, 2 -0.147 1.3e+07 1 0 0.863 0.000106 45700 -0.983 4830 1 0 0.374 0.356 1.1 -0.563 5660 1 0 0.57 0.0464 1.85 PRS_PLINK_1e.06 TRUE 800.3 Fracture of tibia and fibula Both 4 15 18 injuries & poisonings gray50 15, 4 4, 0 4, 0 3, 0 4, 4 0.58 0.795 0.465 0.332 1.79 0.515 91.6 0.418 1.91 0.826 0.083 1.52 0.0143 48.2 PRS_PLINK_1e.06 TRUE 800.4 Fracture of patella Both 2 3 18 injuries & poisonings gray50 3, 2 1, 1 1, 0 1, 1 1, 1 0.139 121 0.999 0 1.15 1.04 1.9 0.00847 28.1 1 0 1.01 0.924 1.08 -0.183 1550 1 0 0.833 0.822 1.49 PRS_PLINK_1e.06 TRUE 801 Fracture of ankle and foot Both 7 36 18 injuries & poisonings gray50 36, 7 9, 1 9, 0 9, 1 9, 4 0.26 0.414 0.529 0.276 1.3 0.631 3.24 -0.518 1.84 0.778 0.109 0.596 0.0121 55 0.636 1.72 0.711 0.148 1.89 0.0184 144000 2.05 1.52 0.178 0.751 7.79 0.677 1240000 PRS_PLINK_1e.06 TRUE 801.1 Fracture of foot Both 2 14 18 injuries & poisonings gray50 14, 2 4, 0 3, 0 3, 1 4, 1 0.951 1.08 0.376 0.424 2.59 0.523 30 -3.66 24100000 1 0 0.0258 1.55e-10 501000 3.81 21800000 1 0 45.1 0.021 3450 PRS_PLINK_1e.06 TRUE 802 Fracture of pelvis Both 0 5 18 injuries & poisonings gray50 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 803 Fracture of upper limb Both 6 23 18 injuries & poisonings gray50 23, 6 6, 0 6, 3 5, 2 6, 1 0.108 0.475 0.82 0.086 1.11 0.407 2.88 2.2 3.06 0.473 0.325 8.98 0.0478 6800 0.684 2.29 0.765 0.116 1.98 0.0106 826 0.646 1.63 0.691 0.16 1.91 0.156 260 PRS_PLINK_1e.06 TRUE 803.1 Fracture of humerus Both 2 6 18 injuries & poisonings gray50 6, 2 2, 0 1, 0 1, 0 2, 2 0.00438 253 1 0 1 0.896 1.25 0.0761 904 1 0 1.08 0.708 1.77 PRS_PLINK_1e.06 TRUE 803.2 Fracture of radius and ulna Both 4 14 18 injuries & poisonings gray50 14, 4 4, 1 3, 1 3, 2 4, 0 -0.258 0.858 0.763 0.117 0.772 0.0383 4.17 -0.171 2170 1 0 0.843 0.0855 9.45 -0.433 195 0.998 0.001 0.648 3.89e-05 149000 0.0223 124 1 0 1.02 0.721 1.55 PRS_PLINK_1e.06 TRUE 803.21 Colles' fracture Both 0 4 18 injuries & poisonings gray50 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 803.3 Fracture of clavicle or scapula Both 0 2 18 injuries & poisonings gray50 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 804 Fracture of hand or wrist Both 8 26 18 injuries & poisonings gray50 26, 8 7, 2 6, 2 6, 3 7, 1 -0.106 0.54 0.844 0.074 0.899 0.345 2.54 -1.3 2.14 0.541 0.267 0.271 7.08e-06 10.4 4.63 3.41 0.175 0.757 102 0.608 1350000 -0.9 1.86 0.629 0.202 0.407 0.00101 11.6 PRS_PLINK_1e.06 TRUE 805 Fracture of vertebral column without mention of spinal cord injury Both 2 8 18 injuries & poisonings gray50 8, 2 2, 0 2, 0 2, 0 2, 2 -2.11 9.36 0.822 0.085 0.121 0.106 0.138 -0.549 1340 1 0 0.577 0.238 2.56 PRS_PLINK_1e.06 TRUE 807 Fracture of ribs Both 2 8 18 injuries & poisonings gray50 8, 2 2, 1 2, 0 2, 0 2, 1 -0.198 1.13 0.861 0.065 0.82 0.137 4.37 0.0132 951 1 0 1.01 0.602 2.09 -0.51 5090 1 0 0.6 0.43 3.38 0.162 335 1 0 1.18 0.0222 18.8 PRS_PLINK_1e.06 TRUE 809 Fracture of unspecified bones Both 6 37 18 injuries & poisonings gray50 37, 6 10, 1 9, 0 9, 2 9, 2 -0.551 0.683 0.42 0.377 0.577 0.118 2.53 -0.296 2.02 0.883 0.054 0.743 0.00463 907 -0.504 1.36 0.71 0.149 0.604 0.0242 1630 1.68 1.64 0.306 0.514 5.35 0.136 364 PRS_PLINK_1e.06 TRUE 816 Cerebral laceration and contusion Both 0 3 18 injuries & poisonings gray50 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 817 Concussion Both 2 22 18 injuries & poisonings gray50 22, 2 6, 1 5, 0 5, 1 6, 0 -0.157 0.741 0.833 0.08 0.855 0.0374 7.54 -0.706 3.35 0.833 0.079 0.494 0.00201 2090 0.784 3.82 0.837 0.077 2.19 0.00569 1390 -0.287 2.11 0.892 0.05 0.751 0.00165 131 PRS_PLINK_1e.06 TRUE 818 Intracranial hemorrhage (injury) Both 0 5 18 injuries & poisonings gray50 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 818.1 Subdural hemorrhage (injury) Both 0 1 18 injuries & poisonings gray50 1, 0 PRS_PLINK_1e.06 TRUE 818.2 Subarachnoid hemorrhage (injury) Both 0 4 18 injuries & poisonings gray50 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 819 Skull and face fracture and other intercranial injury Both 4 37 18 injuries & poisonings gray50 37, 4 10, 1 9, 1 9, 1 9, 0 -0.761 0.567 0.18 0.746 0.467 0.058 1.37 -0.249 1.43 0.862 0.065 0.78 0.00368 18.2 -0.613 1.95 0.753 0.123 0.542 8.05e-05 76.8 -0.307 1.54 0.842 0.075 0.736 0.0139 21.3 PRS_PLINK_1e.06 TRUE 830 Dislocation Both 12 42 18 injuries & poisonings gray50 42, 12 11, 1 10, 3 10, 4 11, 3 -0.117 0.358 0.744 0.128 0.89 0.456 1.8 0.0487 1.54 0.975 0.011 1.05 0.0168 36.9 1.12 1.52 0.461 0.337 3.06 0.131 30100 -0.037 1.3 0.977 0.01 0.964 0.011 30.1 PRS_PLINK_1e.06 TRUE 835 Internal derangement of knee Both 5 27 18 injuries & poisonings gray50 27, 5 7, 1 7, 0 6, 2 7, 2 0.0909 0.486 0.852 0.07 1.1 0.436 3.21 0.422 4.54 0.926 0.033 1.53 2.06e-05 303000 1.54 2.47 0.534 0.273 4.64 0.000358 12400 -0.771 1.65 0.641 0.193 0.462 0.0026 8.32 PRS_PLINK_1e.06 TRUE 836 Traumatic arthropathy Both 2 6 18 injuries & poisonings gray50 6, 2 2, 1 1, 1 1, 0 2, 0 -0.6 234 0.998 0.001 0.549 0.00439 575 -0.0459 2940 1 0 0.955 0.451 1.61 0.0636 3060 1 0 1.07 0.484 4.29 0.108 3080 1 0 1.11 0.531 1.16 PRS_PLINK_1e.06 TRUE 840 Sprains and strains Both 19 43 18 injuries & poisonings gray50 43, 19 10, 4 11, 5 10, 3 11, 7 0.0912 0.292 0.755 0.122 1.1 0.649 1.91 -0.502 1.09 0.645 0.19 0.605 0.0841 4.06 -1.07 1.23 0.383 0.417 0.342 0.0105 2.46 0.471 0.873 0.589 0.23 1.6 0.341 8.05 PRS_PLINK_1e.06 TRUE 840.1 Muscle/tendon sprain Both 2 3 18 injuries & poisonings gray50 3, 2 1, 1 1, 0 1, 1 1, 1 -28 1.43e+09 1 0 6.97e-13 4.11e-41 1.78e+25 0.00409 37.8 1 0 1 0.942 2.91 -0.00619 39.1 1 0 0.994 0.872 1.09 PRS_PLINK_1e.06 TRUE 840.2 Rotator cuff (capsule) sprain Both 7 16 18 injuries & poisonings gray50 16, 7 4, 0 4, 1 4, 2 4, 4 0.593 0.711 0.404 0.394 1.81 0.598 8.98 -0.0383 1060 1 0 0.962 1.24 2.47 3.75 39.6 0.925 0.034 42.4 1.22e-10 1.95e+13 1.4 2.42 0.564 0.248 4.04 0.0734 257 PRS_PLINK_1e.06 TRUE 840.3 Joint/ligament sprain Both 6 40 18 injuries & poisonings gray50 40, 6 9, 2 10, 1 10, 1 10, 2 -0.301 0.412 0.464 0.333 0.74 0.272 1.64 0.176 2.11 0.933 0.03 1.19 0.0143 64.6 -0.407 1.38 0.767 0.115 0.666 0.0145 19.4 0.000757 1.11 0.999 0 1 0.0957 9.11 PRS_PLINK_1e.06 TRUE 841 Sprains and strains of back and neck Both 1 26 18 injuries & poisonings gray50 26, 1 6, 0 6, 0 6, 1 7, 0 -0.0106 0.613 0.986 0.006 0.989 0.146 7.32 1.04 2.45 0.67 0.174 2.83 0.0561 600 PRS_PLINK_1e.06 TRUE 842 Other sprains and strains Both 4 23 18 injuries & poisonings gray50 23, 4 5, 2 6, 1 5, 1 6, 0 -0.685 0.668 0.305 0.516 0.504 0.0325 1.81 -2.17 2.06 0.291 0.536 0.114 0.000436 1.96 -0.851 2.22 0.702 0.154 0.427 0.00123 8.46 -1.92 2.84 0.499 0.302 0.146 0.000244 24.8 PRS_PLINK_1e.06 TRUE 850 Hemorrhage or hematoma complicating a procedure Both 2 24 18 injuries & poisonings gray50 24, 2 5, 0 6, 0 6, 0 6, 2 0.709 0.793 0.371 0.43 2.03 0.251 59.3 0.559 1.64 0.733 0.135 1.75 0.0603 143 PRS_PLINK_1e.06 TRUE 851 Complications of transplants and reattached limbs Both 2 34 18 injuries & poisonings gray50 34, 2 8, 0 8, 0 8, 2 9, 0 0.0913 0.644 0.887 0.052 1.1 0.277 137 0.465 1.5 0.757 0.121 1.59 0.0777 36.2 PRS_PLINK_1e.06 TRUE 853 Complication of colostomy or enterostomy Both 0 3 18 injuries & poisonings gray50 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 854 Complications of cardiac/vascular device, implant, and graft Both 4 25 18 injuries & poisonings gray50 25, 4 6, 0 6, 1 6, 2 6, 1 0.3 0.556 0.589 0.23 1.35 0.504 6.53 0.452 3.04 0.882 0.055 1.57 0.0173 51500 0.72 1.83 0.694 0.159 2.05 0.125 150 0.6 1.97 0.761 0.119 1.82 0.0931 52.9 PRS_PLINK_1e.06 TRUE 855 Complication of nervous system device, implant, and graft Both 1 2 18 injuries & poisonings gray50 2, 1 0, 1 1, 0 0, 1 1, 0 0.0032 72.2 1 0 1 0.967 1.04 PRS_PLINK_1e.06 TRUE 856 Vascular complications of surgery and medical procedures Both 0 2 18 injuries & poisonings gray50 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 857 Mechanical complication of unspecified genitourinary device, implant, and graft Both 4 20 18 injuries & poisonings gray50 20, 4 4, 1 5, 0 5, 3 5, 0 0.334 0.994 0.737 0.133 1.4 0.227 29.8 -0.463 3.93 0.906 0.043 0.629 0.00279 1.3e+11 -0.00901 3.34 0.998 0.001 0.991 0.000289 746 1.19 6.1 0.846 0.073 3.28 0.000383 40500 PRS_PLINK_1e.06 TRUE 858 Complication of internal orthopedic device Both 2 23 18 injuries & poisonings gray50 23, 2 6, 1 6, 0 5, 1 6, 0 -0.0478 0.752 0.949 0.023 0.953 0.205 6.85 0.791 3.35 0.814 0.09 2.2 0.00332 146000 1.63 2.73 0.55 0.259 5.12 0.0688 49600 0.381 3 0.899 0.046 1.46 0.000598 858 PRS_PLINK_1e.06 TRUE 859 Complication due to other implant and internal device Both 1 21 18 injuries & poisonings gray50 21, 1 5, 0 5, 0 5, 1 5, 0 0.211 0.941 0.822 0.085 1.24 0.1 72.4 -0.257 3000 1 0 0.773 0.159 1.53 PRS_PLINK_1e.06 TRUE 860 Bone marrow or stem cell transplant Both 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 870 Open wounds of head; neck; and trunk Both 5 48 18 injuries & poisonings gray50 48, 5 11, 2 12, 0 12, 1 12, 2 -0.0566 0.387 0.884 0.054 0.945 0.451 2.14 -0.00278 2.12 0.999 0 0.997 0.00287 353000 -0.424 1.37 0.757 0.121 0.655 0.028 9.39 -0.0859 1.01 0.932 0.031 0.918 0.127 6.54 PRS_PLINK_1e.06 TRUE 870.1 Open wound or laceration of eye or eyelid Both 0 2 18 injuries & poisonings gray50 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 870.2 Open wound of ear Both 0 3 18 injuries & poisonings gray50 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 870.3 Other open wound of head and face Both 1 13 18 injuries & poisonings gray50 13, 1 3, 0 3, 0 3, 0 3, 1 1.08 1.83 0.556 0.255 2.93 0.0423 153 -0.295 8820 1 0 0.745 0.575 1.91 PRS_PLINK_1e.06 TRUE 870.4 Open wound of nose and sinus Both 1 2 18 injuries & poisonings gray50 2, 1 1, 0 1, 1 1, 0 1, 1 0.0229 67.3 1 0 1.02 0.8 1.1 0.00867 63.7 1 0 1.01 0.952 2.29 PRS_PLINK_1e.06 TRUE 870.5 Open wound of lip and mouth Both 0 7 18 injuries & poisonings gray50 7, 0 2 2 1 2 PRS_PLINK_1e.06 TRUE 870.6 Open wound of neck Both 0 1 18 injuries & poisonings gray50 1, 0 PRS_PLINK_1e.06 TRUE 870.8 Open wound of genital organs Both 1 1 18 injuries & poisonings gray50 1, 1 0.00148 1140 1 0 1 0.868 1.17 PRS_PLINK_1e.06 TRUE 871 Open wounds of extremities Both 7 49 18 injuries & poisonings gray50 49, 7 12, 1 12, 1 12, 1 12, 4 1.34 0.724 0.0653 1.185 3.8 0.99 1900 0.236 1.72 0.891 0.05 1.27 0.0158 187 -0.217 1.34 0.872 0.06 0.805 0.000359 1400 1.39 1.4 0.322 0.492 4.01 0.0955 4910 PRS_PLINK_1e.06 TRUE 871.1 Open wound of hand except finger(s) Both 1 13 18 injuries & poisonings gray50 13, 1 4, 0 3, 0 3, 0 3, 1 -0.0337 0.934 0.971 0.013 0.967 0.0801 6.07 2.42 32.9 0.941 0.026 11.3 0.133 1000 PRS_PLINK_1e.06 TRUE 871.2 Open wound of finger(s) Both 4 25 18 injuries & poisonings gray50 25, 4 7, 0 6, 1 6, 1 6, 2 1.55 1.19 0.192 0.716 4.71 0.595 8060 -0.708 4.23 0.867 0.062 0.493 0.000285 8740 0.348 1.89 0.854 0.069 1.42 0.0542 1460 0.383 2.76 0.89 0.051 1.47 0.00662 1810000 PRS_PLINK_1e.06 TRUE 871.3 Open wound of foot except toe(s) alone Both 1 12 18 injuries & poisonings gray50 12, 1 3, 0 3, 0 3, 0 3, 1 -0.0903 1.67 0.957 0.019 0.914 0.00268 19.3 -1.26 11600 1 0 0.283 0.0172 16.4 PRS_PLINK_1e.06 TRUE 871.4 Open wound of toe(s) Both 2 9 18 injuries & poisonings gray50 9, 2 3, 1 2, 0 2, 0 2, 1 0.841 85 0.992 0.003 2.32 2.22 2.42 -0.224 2850 1 0 0.799 0.0782 2.74 0.0717 23200 1 0 1.07 0.0691 1.52 -6.69e-06 4950 1 0 1 0.441 2.76 PRS_PLINK_1e.06 TRUE 872 Traumatic amputation Both 1 15 18 injuries & poisonings gray50 15, 1 4, 0 4, 0 3, 1 4, 0 -0.349 0.833 0.675 0.171 0.705 0.149 5.19 1.96 18.6 0.916 0.038 7.08 11.6 8.93 PRS_PLINK_1e.06 TRUE 874 Complication of amputation stump Both 0 3 18 injuries & poisonings gray50 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 875 Non-healing surgical wound Both 0 4 18 injuries & poisonings gray50 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 876 Posttraumatic wound infection not elsewhere classified Both 0 9 18 injuries & poisonings gray50 9, 0 3 2 2 2 PRS_PLINK_1e.06 TRUE 907 Injuries to the nervous system Both 2 16 18 injuries & poisonings gray50 16, 2 4, 0 4, 0 4, 1 4, 1 0.624 0.937 0.505 0.296 1.87 0.444 2e+08 -0.476 11200 1 0 0.621 0.28 2.04 -2.81 274 0.992 0.004 0.0599 2.67e-10 11800000 PRS_PLINK_1e.06 TRUE 910 Superficial injury, infected Both 0 3 18 injuries & poisonings gray50 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 911 Blister Both 5 8 18 injuries & poisonings gray50 8, 5 2, 3 2, 0 2, 1 2, 0 -0.236 2.6 0.928 0.033 0.79 0.0135 122 0.00658 520 1 0 1.01 0.807 1.26 0.0161 353 1 0 1.02 0.861 1.23 0.00934 762 1 0 1.01 0.676 1.62 PRS_PLINK_1e.06 TRUE 912 Insect bite Both 0 9 18 injuries & poisonings gray50 9, 0 3 2 2 2 PRS_PLINK_1e.06 TRUE 913 Toxic effect of venom Both 2 6 18 injuries & poisonings gray50 6, 2 2, 1 1, 0 1, 1 2, 0 0.157 1290 1 0 1.17 0.00666 283 0.156 23700 1 0 1.17 0.502 46.8 0.384 18000 1 0 1.47 0.231 10.3 8.91 10800 0.999 0 7410 3.7e-16 3.01e+23 PRS_PLINK_1e.06 TRUE 916 Contusion Both 8 48 18 injuries & poisonings gray50 48, 8 12, 3 12, 1 12, 1 12, 2 -0.376 0.382 0.326 0.487 0.687 0.326 1.44 -0.558 1.2 0.641 0.193 0.572 0.0322 4.93 -2.4 1.56 0.123 0.909 0.0911 0.00139 1.36 0.116 1.09 0.915 0.038 1.12 0.125 10.7 PRS_PLINK_1e.06 TRUE 930 Allergic reaction to food Both 0 10 18 injuries & poisonings gray50 10, 0 3 2 2 3 PRS_PLINK_1e.06 TRUE 931 Contact dermatitis and other eczema due to plants [except food] Both 1 11 13 dermatologic firebrick 11, 1 2, 0 3, 1 2, 0 3, 0 -0.233 1 0.817 0.088 0.792 0.111 4.63 -0.156 11500 1 0 0.855 0.0261 12.3 PRS_PLINK_1e.06 TRUE 938 Dermatitis due to solar radiation Both 8 32 13 dermatologic firebrick 32, 8 7, 2 8, 1 8, 4 8, 1 0.139 0.49 0.776 0.11 1.15 0.462 3.37 -0.757 2.91 0.795 0.1 0.469 1e-05 239 0.616 1.46 0.673 0.172 1.85 0.17 142 1.24 2.52 0.623 0.206 3.45 0.0101 17700 PRS_PLINK_1e.06 TRUE 938.1 Acute dermatitis due to solar radiation Both 0 4 13 dermatologic firebrick 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 938.2 Chronic dermatitis due to solar radiation Both 8 31 13 dermatologic firebrick 31, 8 7, 2 8, 1 7, 3 8, 2 0.138 0.489 0.777 0.11 1.15 0.463 3.35 -0.757 2.91 0.795 0.1 0.469 1e-05 239 0.145 2.32 0.95 0.022 1.16 0.000197 643 1.41 1.53 0.355 0.449 4.11 0.401 3710 PRS_PLINK_1e.06 TRUE 939 Atopic/contact dermatitis due to other or unspecified Both 12 40 13 dermatologic firebrick 40, 12 9, 3 10, 1 10, 4 10, 4 0.789 0.473 0.0953 1.021 2.2 0.974 6.4 -0.277 1.63 0.865 0.063 0.758 0.0198 430 0.766 1.22 0.531 0.275 2.15 0.288 41.5 2.75 1.75 0.115 0.938 15.6 0.917 585000 PRS_PLINK_1e.06 TRUE 939.1 Contact and allergic dermatitis of eyelid Both 0 1 13 dermatologic firebrick 1, 0 PRS_PLINK_1e.06 TRUE 941 Adverse reaction to serum or vaccine Both 0 5 18 injuries & poisonings gray50 5, 0 2 1 1 1 PRS_PLINK_1e.06 TRUE 942 Infusion and transfusion reaction Both 0 4 18 injuries & poisonings gray50 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 946 Anaphylactic shock NOS Both 3 5 18 injuries & poisonings gray50 5, 3 2, 0 1, 0 1, 1 1, 2 0.671 972 0.999 0 1.96 0.643 3.04 -0.00368 46.2 1 0 0.996 0.912 1.17 0.00696 1700 1 0 1.01 0.754 1.41 PRS_PLINK_1e.06 TRUE 947 Urticaria Both 5 15 13 dermatologic firebrick 15, 5 3, 2 4, 1 3, 2 4, 0 -1.07 1.04 0.305 0.515 0.343 0.00103 2.1 -0.18 12.4 0.988 0.005 0.835 0.823 0.847 -0.772 2.59 0.766 0.116 0.462 0.425 9.84 0.602 24300000 1 0 1.83 1.26e-06 1050000 PRS_PLINK_1e.06 TRUE 949 Allergies, other Both 13 40 18 injuries & poisonings gray50 40, 13 9, 6 10, 3 10, 3 10, 1 -0.152 0.376 0.687 0.163 0.859 0.421 1.8 -0.0633 1.66 0.97 0.013 0.939 0.012 109 -1.22 1.15 0.288 0.541 0.295 0.0311 1.88 -0.822 1.29 0.525 0.28 0.439 0.0341 4.3 PRS_PLINK_1e.06 TRUE 952 Spinal cord injury without evidence of spinal bone injury Both 1 8 18 injuries & poisonings gray50 8, 1 2, 0 2, 0 2, 1 2, 0 0.142 53.4 0.998 0.001 1.15 0.0186 46.6 -11.4 45300 1 0 1.12e-05 1.15e-38 4.54e+42 PRS_PLINK_1e.06 TRUE 957 Injury to other and unspecified nerves Both 1 1 18 injuries & poisonings gray50 1, 1 0.000201 229 1 0 1 0.998 1 PRS_PLINK_1e.06 TRUE 958 Certain early complications of trauma or procedure Both 0 10 18 injuries & poisonings gray50 10, 0 3 2 2 3 PRS_PLINK_1e.06 TRUE 958.1 Postoperative shock Both 0 2 18 injuries & poisonings gray50 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 960 Poisoning by antibiotics Both 5 26 18 injuries & poisonings gray50 26, 5 6, 3 6, 0 6, 1 7, 1 -0.501 0.463 0.28 0.553 0.606 0.248 1.28 -1.62 3.41 0.636 0.196 0.199 0.00022 49.5 -0.691 1.74 0.691 0.16 0.501 0.00293 8.35 -1.27 1.58 0.423 0.374 0.281 6.33e-05 2.55 PRS_PLINK_1e.06 TRUE 960.1 Adverse effects of antibacterials (not penicillins) Both 0 3 18 injuries & poisonings gray50 3, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 960.2 Allergy/adverse effect of penicillin Both 3 19 18 injuries & poisonings gray50 19, 3 4, 1 5, 1 4, 0 5, 1 0.144 0.9 0.873 0.059 1.15 0.112 22.6 -1.1 23.1 0.962 0.017 0.332 0.279 0.404 -0.546 18900000 1 0 0.579 0.243 217 0.0659 98.4 0.999 0 1.07 3.44e-05 15.6 PRS_PLINK_1e.06 TRUE 961 Poisoning by other anti-infectives Both 0 9 18 injuries & poisonings gray50 9, 0 3 2 2 2 PRS_PLINK_1e.06 TRUE 961.1 Poisoning/allergy of sulfonamides Both 2 6 18 injuries & poisonings gray50 6, 2 2, 0 1, 0 1, 0 2, 2 2.47 362 0.995 0.002 11.8 2.21e-05 254000 0.118 482 1 0 1.13 0.54 3.8 PRS_PLINK_1e.06 TRUE 962 Poisoning by hormones and synthetic substitutes Both 3 16 18 injuries & poisonings gray50 16, 3 4, 1 4, 1 4, 1 4, 0 -0.334 0.805 0.678 0.169 0.716 0.0834 10.2 3.6 7.94 0.65 0.187 36.6 0.000277 13900000 -3.79 8.37 0.65 0.187 0.0225 5.08e-08 4330 -0.227 2290 1 0 0.797 0.232 1.58 PRS_PLINK_1e.06 TRUE 962.1 Adrenal cortical steroids causing adverse effects in therapeutic use Both 1 8 18 injuries & poisonings gray50 8, 1 2, 0 2, 0 2, 1 2, 0 -5.72e-12 18.7 1 0 1 0.0187 52.5 -0.123 6010 1 0 0.885 0.795 4.61 PRS_PLINK_1e.06 TRUE 962.2 Insulins and antidiabetic agents causing adverse effects in therapeutic use Both 1 1 18 injuries & poisonings gray50 1, 1 0.000539 991 1 0 1 0.936 1.07 PRS_PLINK_1e.06 TRUE 962.3 Hormones and synthetic substitutes causing adverse effects in therapeutic use Both 2 9 18 injuries & poisonings gray50 9, 2 3, 1 2, 1 2, 0 2, 0 -0.716 1.37 0.6 0.222 0.489 0.0339 4.04 0.1 1210 1 0 1.11 0.792 2.21 0.0579 3190 1 0 1.06 0.648 1.19 -0.0304 901 1 0 0.97 0.734 1.15 PRS_PLINK_1e.06 TRUE 963 Poisoning by primarily systemic agents Both 0 25 18 injuries & poisonings gray50 25, 0 6 6 6 6 PRS_PLINK_1e.06 TRUE 963.1 Antineoplastic and immunosuppressive drugs causing adverse effects Both 0 23 18 injuries & poisonings gray50 23, 0 5 6 5 6 PRS_PLINK_1e.06 TRUE 964 Poisoning by agents primarily affecting blood constituents Both 0 13 18 injuries & poisonings gray50 13, 0 3 3 3 3 PRS_PLINK_1e.06 TRUE 964.1 Anticoagulants causing adverse effects Both 0 12 18 injuries & poisonings gray50 12, 0 2 3 3 3 PRS_PLINK_1e.06 TRUE 965 Poisoning by analgesics, antipyretics, and antirheumatics Both 1 5 18 injuries & poisonings gray50 5, 1 2, 0 1, 0 1, 0 1, 1 -2.16 17700 1 0 0.115 0.000208 35.3 0.154 91500 1 0 1.17 1.69e-11 4.58 PRS_PLINK_1e.06 TRUE 965.1 Opiates and related narcotics causing adverse effects in therapeutic use Both 1 16 18 injuries & poisonings gray50 16, 1 3, 0 4, 0 4, 1 4, 0 0.0624 0.861 0.942 0.026 1.06 0.17 23.9 0.253 22500000 1 0 1.29 0.0277 65 PRS_PLINK_1e.06 TRUE 965.3 Salicylates causing adverse effects in therapeutic use Both 0 1 18 injuries & poisonings gray50 1, 0 PRS_PLINK_1e.06 TRUE 966 Poisoning by anticonvulsants and anti-Parkinsonism drugs Both 0 2 18 injuries & poisonings gray50 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 967 Adverse effects of sedatives or other central nervous system depressants and anesthetics Both 0 12 18 injuries & poisonings gray50 12, 0 3 3 3 3 PRS_PLINK_1e.06 TRUE 969 Poisoning by psychotropic agents Both 0 1 18 injuries & poisonings gray50 1, 0 PRS_PLINK_1e.06 TRUE 972 Poisoning by agents primarily affecting the cardiovascular system Both 0 4 18 injuries & poisonings gray50 4, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 972.6 Antihypertensive agents causing adverse effects Both 0 1 18 injuries & poisonings gray50 1, 0 PRS_PLINK_1e.06 TRUE 974 Poisoning by water, mineral, and uric acid metabolism drugs Both 0 1 18 injuries & poisonings gray50 1, 0 PRS_PLINK_1e.06 TRUE 975 Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system Both 0 1 18 injuries & poisonings gray50 1, 0 PRS_PLINK_1e.06 TRUE 976 Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs Both 1 0 18 injuries & poisonings gray50 0, 1 PRS_PLINK_1e.06 TRUE 977 Personal history of allergy to medicinal agents Both 0 21 18 injuries & poisonings gray50 21, 0 5 5 5 5 PRS_PLINK_1e.06 TRUE 979 Adverse drug events and drug allergies Both 5 38 18 injuries & poisonings gray50 38, 5 9, 0 9, 2 9, 1 10, 2 0.477 0.593 0.421 0.376 1.61 0.5 7.87 0.55 2.08 0.792 0.102 1.73 0.0578 31000 1.23 2.04 0.547 0.262 3.4 0.105 1080 0.988 1.45 0.496 0.305 2.69 0.0674 79.2 PRS_PLINK_1e.06 TRUE 980 Encounter for long-term (current) use of antibiotics Both 3 13 1 infectious diseases blue 13, 3 3, 0 3, 0 3, 3 3, 0 0.143 0.726 0.844 0.074 1.15 0.242 73.7 -2.22 16.8 0.895 0.048 0.109 0.0159 0.705 PRS_PLINK_1e.06 TRUE 985 Toxic effect of other metals Both 1 0 18 injuries & poisonings gray50 0, 1 PRS_PLINK_1e.06 TRUE 989 Toxic effect of other substances, chiefly nonmedicinal as to source Both 1 2 18 injuries & poisonings gray50 2, 1 1, 1 1, 0 1, 1 1, 0 0.00638 72.7 1 0 1.01 0.917 1.25 -0.0444 192 1 0 0.957 0.748 1.17 PRS_PLINK_1e.06 TRUE 990 Effects radiation NOS Both 0 21 18 injuries & poisonings gray50 21, 0 6 5 5 5 PRS_PLINK_1e.06 TRUE 994 Sepsis and SIRS Both 1 27 18 injuries & poisonings gray50 27, 1 7, 0 7, 0 6, 0 7, 1 0.397 0.628 0.528 0.278 1.49 0.488 9.45 0.332 1.43 0.816 0.088 1.39 0.0441 25.8 PRS_PLINK_1e.06 TRUE 994.1 Systemic inflammatory response syndrome (SIRS) Both 0 2 18 injuries & poisonings gray50 2, 0 1 1 1 1 PRS_PLINK_1e.06 TRUE 994.2 Sepsis Both 1 27 18 injuries & poisonings gray50 27, 1 7, 0 7, 0 6, 0 7, 1 0.408 0.658 0.535 0.271 1.5 0.476 12.9 0.647 1.54 0.674 0.171 1.91 0.107 38.5 PRS_PLINK_1e.06 TRUE 994.21 Septic shock Both 0 6 18 injuries & poisonings gray50 6, 0 2 1 1 2 PRS_PLINK_1e.06 TRUE