phewas_code phewas_string sex MatchedCases MatchedControls groupnum group color N N_Q1 N_Q2 N_Q3 N_Q4 PRS_BETA PRS_SEBETA PRS_P PRS_LOG10P PRS_OR PRS_CI1 PRS_CI2 Q1Q2_BETA Q1Q2_SEBETA Q1Q2_P Q1Q2_LOG10P Q1Q2_OR Q1Q2_CI1 Q1Q2_CI2 Q1Q3_BETA Q1Q3_SEBETA Q1Q3_P Q1Q3_LOG10P Q1Q3_OR Q1Q3_CI1 Q1Q3_CI2 Q1Q4_BETA Q1Q4_SEBETA Q1Q4_P Q1Q4_LOG10P Q1Q4_OR Q1Q4_CI1 Q1Q4_CI2 predictor 008 Intestinal infection Both 7 45 1 infectious diseases blue 45, 7 11, 6 11, 0 11, 0 11, 1 -0.0665 0.411 0.871 0.06 0.936 0.409 2.05 -1.42 1.35 0.294 0.531 0.242 0.00523 2.6 -1.27 1.23 0.304 0.517 0.282 0.00637 2.3 -0.547 1.19 0.645 0.19 0.579 0.0427 6.04 PRS_PLINK_5e.04 008.5 Bacterial enteritis Both 2 16 1 infectious diseases blue 16, 2 4, 2 4, 0 4, 0 4, 0 -0.619 1.02 0.545 0.263 0.538 0.0705 16.3 4.63 1300 0.997 0.001 103 9.17e-25 1.64e+16 -2.06 29.4 0.944 0.025 0.127 0.00507 0.307 2.23 735 0.998 0.001 9.28 0.012 152 PRS_PLINK_5e.04 008.52 Intestinal infection due to C. difficile Both 1 11 1 infectious diseases blue 11, 1 3, 1 3, 0 2, 0 3, 0 0.401 2.2 0.856 0.068 1.49 0.0433 43.1 -0.0739 11100000 1 0 0.929 0.0103 2.52 0.0903 1140 1 0 1.09 0.8 1.22 0.0511 270 1 0 1.05 0.83 1.51 PRS_PLINK_5e.04 008.6 Viral Enteritis Both 1 13 1 infectious diseases blue 13, 1 4, 1 3, 0 3, 0 3, 0 0.0555 0.843 0.947 0.023 1.06 0.19 6.57 -0.0234 55.6 1 0 0.977 0.763 1.31 0.683 92.7 0.994 0.003 1.98 1.83 2.32 0.15 187 0.999 0 1.16 0.726 2.27 PRS_PLINK_5e.04 010 Tuberculosis Both 2 3 1 infectious diseases blue 3, 2 1, 2 1, 0 1, 0 1, 2 0.0181 1300 1 0 1.02 0.171 27.6 -1.25e-06 6010 1 0 1 0.328 3.59 1.71e-05 2930 1 0 1 0.421 1.55 PRS_PLINK_5e.04 031 Diseases due to other mycobacteria Both 1 2 1 infectious diseases blue 2, 1 1, 1 1, 0 1, 1 1, 0 -0.177 6160 1 0 0.838 0.0317 15.5 1.21 6800 1 0 3.35 0.271 134 PRS_PLINK_5e.04 038 Septicemia Both 1 34 1 infectious diseases blue 34, 1 9, 0 8, 0 8, 1 9, 0 -0.0828 0.776 0.915 0.039 0.921 0.00391 5.82 0.659 1.62 0.684 0.165 1.93 0.0345 3260 PRS_PLINK_5e.04 038.1 Gram negative septicemia Both 1 9 1 infectious diseases blue 9, 1 3, 0 2, 0 2, 1 2, 0 0.437 5.95 0.941 0.026 1.55 0.00422 568 0.0179 867 1 0 1.02 0.844 1.26 PRS_PLINK_5e.04 038.2 Gram positive septicemia Both 0 3 1 infectious diseases blue 3, 0 1 1 1 1 PRS_PLINK_5e.04 038.3 Bacteremia Both 0 18 1 infectious diseases blue 18, 0 5 4 4 5 PRS_PLINK_5e.04 041 Bacterial infection NOS Both 4 52 1 infectious diseases blue 52, 4 13, 3 13, 0 13, 1 13, 0 -0.329 0.506 0.515 0.288 0.719 0.165 2.05 -2.19 1.8 0.223 0.651 0.112 3.44e-08 3.3 -0.638 1.17 0.585 0.233 0.529 0.0213 5.33 0.0414 1.72 0.981 0.008 1.04 6.82e-05 324000 PRS_PLINK_5e.04 041.1 Staphylococcus infections Both 2 26 1 infectious diseases blue 26, 2 7, 2 6, 0 6, 0 7, 0 0.427 0.813 0.6 0.222 1.53 0.167 27.8 -0.835 1.7 0.624 0.205 0.434 0.000987 337 1.07 3.07 0.726 0.139 2.93 1.85e-05 1150 -0.401 2.64 0.879 0.056 0.67 0.00029 11800 PRS_PLINK_5e.04 041.11 Methicillin sensitive Staphylococcus aureus Both 2 16 1 infectious diseases blue 16, 2 4, 2 4, 0 4, 0 4, 0 0.228 1.05 0.829 0.082 1.26 0.0396 13.5 0.0512 3.2 0.987 0.006 1.05 1.82e-06 10300 -0.0734 2.77 0.979 0.009 0.929 0.0141 52 1.09 11.3 0.923 0.035 2.98 2.62 3.29 PRS_PLINK_5e.04 041.12 Methicillin resistant Staphylococcus aureus Both 2 14 1 infectious diseases blue 14, 2 4, 2 3, 0 3, 0 4, 0 0.271 2.02 0.893 0.049 1.31 0.0188 99.6 0.213 4 0.958 0.019 1.24 1.22 2.41 -0.279 16.4 0.986 0.006 0.757 0.111 5.13 -2.54 139 0.985 0.006 0.079 0.0676 0.0923 PRS_PLINK_5e.04 041.2 Streptococcus infection Both 2 17 1 infectious diseases blue 17, 2 5, 1 4, 0 4, 1 4, 0 -0.277 1.06 0.794 0.1 0.758 0.0322 6.05 -0.0268 529 1 0 0.974 0.484 1.26 2.16 5.48 0.693 0.16 8.71 0.00331 1150000 0.0296 911 1 0 1.03 0.73 3.4 PRS_PLINK_5e.04 041.21 Rheumatic fever / chorea Both 0 1 1 infectious diseases blue 1, 0 PRS_PLINK_5e.04 041.4 E. coli Both 2 12 1 infectious diseases blue 12, 2 3, 0 3, 1 3, 1 3, 0 -0.375 1.76 0.831 0.08 0.687 0.00524 10.5 0.125 2050000 1 0 1.13 0.805 2.3 0.29 571 1 0 1.34 0.0121 56.9 PRS_PLINK_5e.04 041.8 H. pylori Both 0 2 1 infectious diseases blue 2, 0 1 1 1 1 PRS_PLINK_5e.04 041.9 Infection with drug-resistant microorganisms Both 0 5 1 infectious diseases blue 5, 0 2 1 1 1 PRS_PLINK_5e.04 053 Herpes zoster Both 3 22 1 infectious diseases blue 22, 3 6, 2 5, 1 5, 0 6, 0 -0.705 0.979 0.472 0.326 0.494 0.012 3.48 -1.12 5.33 0.834 0.079 0.327 0.000895 70.6 0.0434 1.89 0.982 0.008 1.04 0.00625 51.8 -0.511 11.1 0.963 0.016 0.6 0.000264 1170 PRS_PLINK_5e.04 053.1 Herpes zoster with nervous system complications Both 1 3 1 infectious diseases blue 3, 1 1, 1 1, 0 1, 0 1, 1 0.000724 69.1 1 0 1 0.336 2.12 -0.00469 56.1 1 0 0.995 0.934 1.12 -0.0176 225 1 0 0.983 0.332 1.08 PRS_PLINK_5e.04 054 Herpes simplex Both 3 22 1 infectious diseases blue 22, 3 6, 1 5, 0 5, 1 6, 1 0.954 0.722 0.187 0.729 2.6 0.685 22.3 0.649 2.94 0.825 0.083 1.91 0.00281 129000 0.391 1.97 0.842 0.074 1.48 0.00937 59.7 3.57 4.66 0.444 0.352 35.4 0.00612 43800000 PRS_PLINK_5e.04 070 Viral hepatitis Both 1 8 1 infectious diseases blue 8, 1 2, 1 2, 0 2, 0 2, 0 0.105 293000 1 0 1.11 1.05 1.21 -0.838 4900 1 0 0.433 0.00303 113 0.0572 1400 1 0 1.06 0.419 1.18 -1.22 1.16e+09 1 0 0.294 9.19e-06 58200 PRS_PLINK_5e.04 070.2 Viral hepatitis B Both 1 1 1 infectious diseases blue 1, 1 -0.0413 82.5 1 0 0.96 0.941 1.08 PRS_PLINK_5e.04 070.3 Viral hepatitis C Both 0 7 1 infectious diseases blue 7, 0 2 2 1 2 PRS_PLINK_5e.04 070.4 Chronic hepatitis Both 0 1 1 infectious diseases blue 1, 0 PRS_PLINK_5e.04 070.9 Hepatitis NOS Both 3 9 1 infectious diseases blue 9, 3 3, 2 2, 0 2, 0 2, 1 -0.704 3.11 0.821 0.086 0.495 0.43 0.56 -0.118 1010 1 0 0.889 0.0802 2.84 1.66 2560 0.999 0 5.26 5.38e-05 33400 -0.00636 5590000 1 0 0.994 0.00924 17.1 PRS_PLINK_5e.04 071 Human immunodeficiency virus [HIV] disease Both 0 2 1 infectious diseases blue 2, 0 1 1 1 1 PRS_PLINK_5e.04 071.1 HIV infection, symptomatic Both 0 2 1 infectious diseases blue 2, 0 1 1 1 1 PRS_PLINK_5e.04 078 Viral warts & HPV Both 10 34 1 infectious diseases blue 34, 10 9, 3 8, 4 8, 1 9, 2 -0.762 0.574 0.184 0.735 0.467 0.0937 1.25 0.174 1.18 0.883 0.054 1.19 0.0577 11.8 -0.201 1.41 0.887 0.052 0.818 0.0955 11.8 -0.748 1.4 0.594 0.226 0.473 0.00893 4.24 PRS_PLINK_5e.04 079 Viral infection Both 13 38 1 infectious diseases blue 38, 13 10, 4 9, 3 9, 2 10, 3 -0.0251 0.358 0.944 0.025 0.975 0.48 1.88 -0.767 1.28 0.549 0.26 0.464 0.015 4.38 -0.207 1.51 0.891 0.05 0.813 0.037 12 0.526 1.11 0.634 0.198 1.69 0.25 12.4 PRS_PLINK_5e.04 079.1 Varicella infection Both 8 32 1 infectious diseases blue 32, 8 8, 3 8, 1 8, 2 8, 1 -0.195 0.58 0.737 0.133 0.823 0.175 2.54 -0.624 1.5 0.677 0.17 0.536 0.0122 7.12 -0.863 1.82 0.636 0.197 0.422 0.000139 26.5 -0.118 2.02 0.953 0.021 0.888 0.00371 33.9 PRS_PLINK_5e.04 079.2 Infectious mononucleosis Both 0 4 1 infectious diseases blue 4, 0 1 1 1 1 PRS_PLINK_5e.04 079.9 Viremia, NOS Both 2 12 1 infectious diseases blue 12, 2 3, 0 3, 2 3, 0 3, 0 0.692 2.12 0.745 0.128 2 0.0302 213 3.22 16.6 0.846 0.072 25 24.3 170 PRS_PLINK_5e.04 080 Postoperative infection Both 0 29 1 infectious diseases blue 29, 0 8 7 7 7 PRS_PLINK_5e.04 081 Infection/inflammation of internal prosthetic device; implant; and graft Both 3 15 1 infectious diseases blue 15, 3 4, 2 4, 0 3, 1 4, 0 -0.256 1.33 0.848 0.072 0.774 0.0632 547 0.181 2.4 0.94 0.027 1.2 0.0283 47.3 -0.326 18300000 1 0 0.722 2.52e-06 4010000 -0.000951 846 1 0 0.999 0.212 6.36 PRS_PLINK_5e.04 090 Sexually transmitted infections (not HIV or hepatitis) Both 2 19 1 infectious diseases blue 19, 2 5, 0 5, 0 4, 0 5, 2 0.813 0.971 0.402 0.396 2.26 0.496 113 0.325 1.87 0.862 0.064 1.38 0.0968 46.2 PRS_PLINK_5e.04 110 Dermatophytosis / Dermatomycosis Both 13 33 1 infectious diseases blue 33, 13 9, 1 8, 4 8, 4 8, 4 0.605 0.457 0.186 0.73 1.83 0.801 5.07 0.773 1.32 0.558 0.253 2.17 0.185 34.3 1.2 1.32 0.362 0.441 3.32 0.356 1980 0.0943 1.28 0.941 0.026 1.1 0.0238 11.2 PRS_PLINK_5e.04 110.1 Dermatophytosis Both 13 31 1 infectious diseases blue 31, 13 8, 1 8, 4 7, 4 8, 4 0.567 0.47 0.228 0.643 1.76 0.752 5.12 0.763 1.31 0.56 0.252 2.14 0.198 33.3 1.14 1.28 0.375 0.426 3.12 0.37 39.5 0.0611 1.28 0.962 0.017 1.06 0.00722 11.4 PRS_PLINK_5e.04 110.11 Dermatophytosis of nail Both 9 18 1 infectious diseases blue 18, 9 5, 3 4, 1 4, 2 5, 3 0.16 0.677 0.813 0.09 1.17 0.304 8.33 0.537 2.63 0.838 0.077 1.71 0.0167 85.5 0.0729 2.93 0.98 0.009 1.08 0.983 1.95 -1.46 2.14 0.493 0.307 0.231 0.00161 7.44 PRS_PLINK_5e.04 110.12 Althete's foot Both 4 15 1 infectious diseases blue 15, 4 4, 1 4, 2 3, 0 4, 1 -0.133 0.767 0.862 0.064 0.876 0.107 3.47 0.111 433 1 0 1.12 0.783 1.49 0.0749 602 1 0 1.08 0.716 2.59 0.934 178 0.996 0.002 2.55 5.82 30.7 PRS_PLINK_5e.04 110.13 Dermatophytosis of the body Both 2 16 1 infectious diseases blue 16, 2 4, 0 4, 0 4, 2 4, 0 -0.0691 0.726 0.924 0.034 0.933 0.19 3.7 0.811 2.17 0.709 0.149 2.25 0.091 65.6 PRS_PLINK_5e.04 110.2 Dermatomycoses Both 2 7 1 infectious diseases blue 7, 2 2, 0 2, 1 1, 1 2, 0 0.775 15.7 0.961 0.017 2.17 0.108 44.5 -0.0956 12900 1 0 0.909 0.112 3.77 0.0885 2460 1 0 1.09 0.823 1.28 PRS_PLINK_5e.04 112 Candidiasis Both 7 35 1 infectious diseases blue 35, 7 9, 2 9, 2 8, 2 9, 1 -0.152 0.65 0.815 0.089 0.859 0.19 3.54 0.074 1.55 0.962 0.017 1.08 0.0274 93.8 -0.0944 1.66 0.955 0.02 0.91 0.000421 5670 1.72 2.33 0.46 0.337 5.6 0.00804 1860000 PRS_PLINK_5e.04 112.3 Candidiasis of skin and nails Both 0 4 1 infectious diseases blue 4, 0 1 1 1 1 PRS_PLINK_5e.04 117 Mycoses Both 2 4 1 infectious diseases blue 4, 2 1, 0 1, 2 1, 0 1, 0 0.0446 798 1 0 1.05 0.853 1.38 1.87 8760 1 0 6.52 0.00043 1.44e+08 PRS_PLINK_5e.04 117.4 Aspergillosis Both 2 1 1 infectious diseases blue 1, 2 0.0186 4990 1 0 1.02 0.668 1.27 PRS_PLINK_5e.04 130 Spirochetal infection Both 1 3 1 infectious diseases blue 3, 1 1, 1 1, 0 1, 0 1, 1 -3.13 1.96e+08 1 0 0.0436 2.4e-06 0.127 -0.0524 1870 1 0 0.949 0.518 1.62 -0.29 11200 1 0 0.748 0.00516 3.85 PRS_PLINK_5e.04 130.1 Lyme disease Both 0 2 1 infectious diseases blue 2, 0 1 1 1 1 PRS_PLINK_5e.04 131 Protozoan infection Both 0 2 1 infectious diseases blue 2, 0 1 1 1 1 PRS_PLINK_5e.04 134 Helminthiases Both 1 1 1 infectious diseases blue 1, 1 -0.375 82.2 0.996 0.002 0.687 0.66 2.04 PRS_PLINK_5e.04 134.1 Intestinal helminthiases Both 1 0 1 infectious diseases blue 0, 1 PRS_PLINK_5e.04 136 Other infectious and parasitic diseases Both 6 41 1 infectious diseases blue 41, 6 11, 1 10, 2 10, 2 10, 1 0.371 0.563 0.51 0.292 1.45 0.381 6.31 0.491 1.56 0.753 0.123 1.63 0.0707 352 -0.174 1.39 0.901 0.045 0.84 0.00994 56.3 -0.153 1.59 0.923 0.035 0.858 0.00313 135 PRS_PLINK_5e.04 145 Cancer of mouth Both 1 10 2 neoplasms darkcyan 10, 1 3, 1 2, 0 2, 0 3, 0 0.0796 2.26 0.972 0.012 1.08 0.02 70.8 0.15 125 0.999 0 1.16 0.00355 225 0.356 232 0.999 0.001 1.43 0.453 4 0.506 1490 1 0 1.66 0.279 1.74 PRS_PLINK_5e.04 145.1 Cancer of lip Both 0 1 2 neoplasms darkcyan 1, 0 PRS_PLINK_5e.04 145.2 Cancer of tongue Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_5e.04 145.3 Cancer of major salivary glands Both 1 2 2 neoplasms darkcyan 2, 1 1, 1 1, 0 1, 1 1, 0 0.00354 259 1 0 1 0.942 1.13 -0.556 3660 1 0 0.574 0.5 1.04 PRS_PLINK_5e.04 145.4 Cancer of the gums Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_5e.04 149 Cancer of larynx, pharynx, nasal cavities Both 1 10 2 neoplasms darkcyan 10, 1 3, 1 2, 0 2, 0 3, 0 -0.135 2.68 0.96 0.018 0.874 0.0125 56.8 0.00654 86.8 1 0 1.01 0.628 1.51 0.0521 367 1 0 1.05 0.783 1.57 0.115 11100 1 0 1.12 0.123 83.9 PRS_PLINK_5e.04 149.1 Cancer of oropharynx Both 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_5e.04 149.2 Cancer of nasopharynx Both 0 1 2 neoplasms darkcyan 1, 0 PRS_PLINK_5e.04 149.4 Cancer of larynx Both 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_5e.04 149.5 Hx of malignant neoplasm of oral cavity and pharynx Both 1 3 2 neoplasms darkcyan 3, 1 1, 1 1, 0 1, 0 1, 1 0.113 3520 1 0 1.12 0.449 3.03 0.000749 9.66 1 0 1 0.982 1.02 0.00766 37.3 1 0 1.01 0.961 1.18 PRS_PLINK_5e.04 149.9 Cancer of of nasal cavities Both 0 1 2 neoplasms darkcyan 1, 0 PRS_PLINK_5e.04 150 Cancer of esophagus Both 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_5e.04 151 Cancer of stomach Both 1 1 2 neoplasms darkcyan 1, 1 -0.00166 49.5 1 0 0.998 0.972 1.02 PRS_PLINK_5e.04 153 Colorectal cancer Both 0 9 2 neoplasms darkcyan 9, 0 3 2 2 2 PRS_PLINK_5e.04 153.2 Colon cancer Both 0 6 2 neoplasms darkcyan 6, 0 2 1 1 2 PRS_PLINK_5e.04 153.3 Malignant neoplasm of rectum, rectosigmoid junction, and anus Both 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_5e.04 155 Cancer of liver and intrahepatic bile duct Both 0 4 2 neoplasms darkcyan 4, 0 1 1 1 1 PRS_PLINK_5e.04 155.1 Malignant neoplasm of liver, primary Both 0 4 2 neoplasms darkcyan 4, 0 1 1 1 1 PRS_PLINK_5e.04 157 Pancreatic cancer Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_5e.04 158 Neoplasm of unspecified nature of digestive system Both 2 10 2 neoplasms darkcyan 10, 2 3, 0 2, 2 2, 0 3, 0 -0.345 1.26 0.784 0.106 0.708 0.00603 5.09 0.168 1530 1 0 1.18 0.866 3.17 PRS_PLINK_5e.04 159 Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum Both 1 9 2 neoplasms darkcyan 9, 1 3, 1 2, 0 2, 0 2, 0 1.3 6.9 0.851 0.07 3.67 3.31 4.02 0.00551 115 1 0 1.01 0.663 1.8 0.33 5730 1 0 1.39 0.343 1.67 0.184 5530 1 0 1.2 0.287 2.04 PRS_PLINK_5e.04 159.2 Malignant neoplasm of small intestine, including duodenum Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_5e.04 159.3 Malignant neoplasm of gallbladder and extrahepatic bile ducts Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_5e.04 159.4 Malignant neoplasm of retroperitoneum and peritoneum Both 0 1 2 neoplasms darkcyan 1, 0 PRS_PLINK_5e.04 165 Cancer within the respiratory system Both 0 12 2 neoplasms darkcyan 12, 0 3 3 3 3 PRS_PLINK_5e.04 165.1 Cancer of bronchus; lung Both 0 10 2 neoplasms darkcyan 10, 0 3 2 2 3 PRS_PLINK_5e.04 170 Cancer of bone and connective tissue Both 0 15 2 neoplasms darkcyan 15, 0 4 4 3 4 PRS_PLINK_5e.04 170.1 Bone cancer Both 0 12 2 neoplasms darkcyan 12, 0 3 3 3 3 PRS_PLINK_5e.04 170.2 Cancer of connective tissue Both 0 5 2 neoplasms darkcyan 5, 0 2 1 1 1 PRS_PLINK_5e.04 172 Skin cancer Both 5 43 2 neoplasms darkcyan 43, 5 11, 0 11, 4 10, 0 11, 1 -0.166 0.521 0.749 0.125 0.847 0.261 2.57 2.61 1.77 0.14 0.854 13.6 0.129 1710 0.646 1.55 0.678 0.169 1.91 0.00865 133 PRS_PLINK_5e.04 172.1 Melanomas of skin, dx or hx Both 4 33 2 neoplasms darkcyan 33, 4 9, 0 8, 4 8, 0 8, 0 -1.01 0.717 0.16 0.795 0.366 0.0345 1.42 2.18 1.73 0.207 0.684 8.83 0.0422 961 PRS_PLINK_5e.04 172.11 Melanomas of skin Both 1 19 2 neoplasms darkcyan 19, 1 5, 0 5, 0 4, 1 5, 0 0.22 0.968 0.821 0.086 1.25 0.137 25 -3.79 33.5 0.91 0.041 0.0226 0.0177 0.029 PRS_PLINK_5e.04 172.2 Other non-epithelial cancer of skin Both 4 37 2 neoplasms darkcyan 37, 4 10, 2 9, 1 9, 0 9, 1 -0.15 0.539 0.781 0.108 0.861 0.259 2.57 1.81 2.12 0.392 0.407 6.11 0.135 4e+05 0.128 1.75 0.941 0.026 1.14 0.00422 481 0.319 1.62 0.844 0.074 1.38 0.0259 1120 PRS_PLINK_5e.04 172.21 Basal cell carcinoma Both 4 22 2 neoplasms darkcyan 22, 4 6, 2 5, 1 5, 0 6, 1 -0.38 0.696 0.585 0.233 0.684 0.169 2.38 1.35 2.4 0.573 0.242 3.87 0.00989 9390 -2.21 5.3 0.678 0.169 0.11 1.03e-08 296 2.2 3.86 0.568 0.246 9.04 0.00234 339 PRS_PLINK_5e.04 172.22 Squamous cell carcinoma Both 0 12 2 neoplasms darkcyan 12, 0 3 3 3 3 PRS_PLINK_5e.04 172.3 Carcinoma in situ of skin Both 0 11 2 neoplasms darkcyan 11, 0 3 3 2 3 PRS_PLINK_5e.04 173 Neoplasm of uncertain behavior of skin Both 1 26 2 neoplasms darkcyan 26, 1 7, 1 6, 0 6, 0 7, 0 -0.132 1 0.895 0.048 0.877 0.046 17.2 0.0616 2.38 0.979 0.009 1.06 0.00579 624 0.288 2.67 0.914 0.039 1.33 0.00337 1570 0.23 3.28 0.944 0.025 1.26 6.41e-06 1210 PRS_PLINK_5e.04 174 Breast cancer Both 3 18 2 neoplasms darkcyan 18, 3 5, 0 4, 0 4, 0 5, 3 0.984 0.894 0.271 0.566 2.67 0.578 28.9 0.669 2.62 0.799 0.098 1.95 0.00867 8410 PRS_PLINK_5e.04 174.1 Breast cancer [female] Female 3 19 2 neoplasms darkcyan 19, 3 5, 0 5, 0 4, 0 5, 3 0.897 0.857 0.296 0.529 2.45 0.556 18.3 0.561 2.6 0.829 0.081 1.75 0.00798 1310 PRS_PLINK_5e.04 174.11 Malignant neoplasm of female breast Female 3 18 2 neoplasms darkcyan 18, 3 5, 0 4, 0 4, 0 5, 3 0.984 0.894 0.271 0.566 2.67 0.578 28.9 0.669 2.62 0.799 0.098 1.95 0.00867 8410 PRS_PLINK_5e.04 174.3 Neoplasm of uncertain behavior of breast Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_5e.04 175 Acquired absence of breast Female 1 5 2 neoplasms darkcyan 5, 1 2, 0 1, 0 1, 0 1, 1 -3e-04 656 1 0 1 0.363 2.16 -1.16 109000 1 0 0.315 0.149 213000 PRS_PLINK_5e.04 180 Cervical cancer and dysplasia Female 2 11 2 neoplasms darkcyan 11, 2 3, 0 3, 0 2, 0 3, 2 0.995 1.49 0.505 0.297 2.7 0.213 153 0.0135 189 1 0 1.01 0.622 1.3 PRS_PLINK_5e.04 180.1 Cervical cancer Female 1 4 2 neoplasms darkcyan 4, 1 1, 0 1, 0 1, 0 1, 1 -0.859 16500 1 0 0.423 0.00957 70.1 6.95 1.8e+09 1 0 1040 2e-21 1.71e+24 PRS_PLINK_5e.04 180.3 Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia] Female 1 11 2 neoplasms darkcyan 11, 1 3, 0 3, 0 2, 0 3, 1 0.431 1.8 0.811 0.091 1.54 0.0381 96 -5.35 1910 0.998 0.001 0.00475 1.13e-10 114000 PRS_PLINK_5e.04 182 Malignant neoplasm of uterus Female 0 5 2 neoplasms darkcyan 5, 0 2 1 1 1 PRS_PLINK_5e.04 184 Cancer of other female genital organs Female 0 6 2 neoplasms darkcyan 6, 0 2 1 1 2 PRS_PLINK_5e.04 184.1 Malignant neoplasm of ovary and other uterine adnexa Female 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_5e.04 184.11 Malignant neoplasm of ovary Female 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_5e.04 184.2 Cancer of other female genital organs (excluding uterus and ovary) Female 0 5 2 neoplasms darkcyan 5, 0 2 1 1 1 PRS_PLINK_5e.04 185 Cancer of prostate Male 0 9 2 neoplasms darkcyan 9, 0 3 2 2 2 PRS_PLINK_5e.04 187 Cancer of other male genital organs Male 1 2 2 neoplasms darkcyan 2, 1 1, 1 1, 0 1, 1 1, 0 1.38 4560 1 0 3.99 0.842 34.4 9.41 422000 1 0 12200 2.47e-09 1.21e+15 PRS_PLINK_5e.04 187.2 Malignant neoplasm of testis Male 1 3 2 neoplasms darkcyan 3, 1 1, 1 1, 0 1, 0 1, 1 -0.121 1550 1 0 0.886 0.34 1.4 -0.189 2620 1 0 0.828 0.204 1.6 -0.344 6750 1 0 0.709 0.552 2.45 PRS_PLINK_5e.04 187.8 Neoplasm of uncertain behavior of male genital organs Male 0 1 2 neoplasms darkcyan 1, 0 PRS_PLINK_5e.04 189 Cancer of urinary organs (incl. kidney and bladder) Both 0 19 2 neoplasms darkcyan 19, 0 5 5 4 5 PRS_PLINK_5e.04 189.1 Cancer of kidney and renal pelvis Both 0 10 2 neoplasms darkcyan 10, 0 3 2 2 3 PRS_PLINK_5e.04 189.11 Malignant neoplasm of kidney, except pelvis Both 0 9 2 neoplasms darkcyan 9, 0 3 2 2 2 PRS_PLINK_5e.04 189.12 Malignant neoplasm of renal pelvis Both 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_5e.04 189.2 Cancer of bladder Both 0 10 2 neoplasms darkcyan 10, 0 3 2 2 3 PRS_PLINK_5e.04 189.21 Malignant neoplasm of bladder Both 0 8 2 neoplasms darkcyan 8, 0 2 2 2 2 PRS_PLINK_5e.04 189.4 Malignant neoplasm of other urinary organs Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_5e.04 190 Cancer of eye Both 0 1 2 neoplasms darkcyan 1, 0 PRS_PLINK_5e.04 191 Manlignant and unknown neoplasms of brain and nervous system Both 0 10 2 neoplasms darkcyan 10, 0 3 2 2 3 PRS_PLINK_5e.04 191.1 Cancer of brain and nervous system Both 0 7 2 neoplasms darkcyan 7, 0 2 2 1 2 PRS_PLINK_5e.04 191.11 Cancer of brain Both 0 8 2 neoplasms darkcyan 8, 0 2 2 2 2 PRS_PLINK_5e.04 193 Thyroid cancer Both 0 16 2 neoplasms darkcyan 16, 0 4 4 4 4 PRS_PLINK_5e.04 194 Cancer of other endocrine glands Both 0 11 2 neoplasms darkcyan 11, 0 3 3 2 3 PRS_PLINK_5e.04 195 Cancer, suspected or other Both 9 48 2 neoplasms darkcyan 48, 9 12, 1 12, 5 12, 0 12, 3 -0.351 0.46 0.445 0.352 0.704 0.261 1.69 0.581 1.08 0.589 0.23 1.79 0.116 17.9 -1.08 1.44 0.455 0.342 0.341 0.00569 5.54 -1.11 1.56 0.477 0.321 0.33 0.000284 6.88 PRS_PLINK_5e.04 195.1 Malignant neoplasm, other Both 8 49 2 neoplasms darkcyan 49, 8 13, 1 12, 4 12, 0 12, 3 -0.295 0.452 0.514 0.289 0.745 0.281 1.77 0.506 1.06 0.634 0.198 1.66 0.0686 15.6 -0.891 1.38 0.517 0.286 0.41 0.00808 6.6 -1.01 1.57 0.519 0.285 0.365 0.000723 8.2 PRS_PLINK_5e.04 195.3 Malignant neoplasm of head, face, and neck Both 0 8 2 neoplasms darkcyan 8, 0 2 2 2 2 PRS_PLINK_5e.04 196 Radiotherapy Both 0 14 2 neoplasms darkcyan 14, 0 4 3 3 4 PRS_PLINK_5e.04 197 Chemotherapy Both 1 33 2 neoplasms darkcyan 33, 1 9, 0 8, 1 8, 0 8, 0 -0.138 0.81 0.864 0.063 0.871 0.00705 10.3 1.5 2.06 0.467 0.331 4.46 0.0459 5270 PRS_PLINK_5e.04 198 Secondary malignant neoplasm Both 0 31 2 neoplasms darkcyan 31, 0 8 8 7 8 PRS_PLINK_5e.04 198.1 Secondary malignancy of lymph nodes Both 0 25 2 neoplasms darkcyan 25, 0 7 6 6 6 PRS_PLINK_5e.04 198.2 Secondary malignancy of respiratory organs Both 0 6 2 neoplasms darkcyan 6, 0 2 1 1 2 PRS_PLINK_5e.04 198.3 Secondary malignant neoplasm of digestive systems Both 0 5 2 neoplasms darkcyan 5, 0 2 1 1 1 PRS_PLINK_5e.04 198.4 Secondary malignant neoplasm of liver Both 0 6 2 neoplasms darkcyan 6, 0 2 1 1 2 PRS_PLINK_5e.04 198.5 Secondary malignancy of brain/spine Both 0 7 2 neoplasms darkcyan 7, 0 2 2 1 2 PRS_PLINK_5e.04 198.6 Secondary malignancy of bone Both 0 9 2 neoplasms darkcyan 9, 0 3 2 2 2 PRS_PLINK_5e.04 199 Neoplasm of uncertain behavior Both 4 48 2 neoplasms darkcyan 48, 4 12, 1 12, 2 12, 0 12, 1 0.287 0.567 0.612 0.213 1.33 0.068 8.2 -1.06 1.4 0.449 0.348 0.346 0.00602 5.29 -0.769 1.27 0.545 0.263 0.464 0.0304 4.51 -0.448 1.24 0.718 0.144 0.639 0.0348 6.99 PRS_PLINK_5e.04 199.4 Neurofibromatosis Both 0 1 2 neoplasms darkcyan 1, 0 PRS_PLINK_5e.04 200 Myeloproliferative disease Both 0 13 2 neoplasms darkcyan 13, 0 4 3 3 3 PRS_PLINK_5e.04 200.1 Polycythemia vera Both 0 5 2 neoplasms darkcyan 5, 0 2 1 1 1 PRS_PLINK_5e.04 201 Hodgkin's disease Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_5e.04 202 Cancer of other lymphoid, histiocytic tissue Both 1 15 2 neoplasms darkcyan 15, 1 4, 0 4, 0 3, 0 4, 1 0.488 1.3 0.707 0.151 1.63 0.173 1970 -0.00306 239 1 0 0.997 0.643 1.99 PRS_PLINK_5e.04 202.2 Non-Hodgkins lymphoma Both 1 14 2 neoplasms darkcyan 14, 1 4, 0 3, 0 3, 0 4, 1 0.388 1.2 0.746 0.127 1.47 0.211 21.8 0.000473 246 1 0 1 0.671 1.35 PRS_PLINK_5e.04 202.21 Nodular lymphoma Both 1 8 2 neoplasms darkcyan 8, 1 2, 0 2, 0 2, 0 2, 1 -1.2 28.8 0.967 0.015 0.302 0.00261 0.325 -5.78e-05 2050 1 0 1 0.482 2.07 PRS_PLINK_5e.04 202.22 Reticulosarcoma Both 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_5e.04 202.24 Large cell lymphoma Both 0 1 2 neoplasms darkcyan 1, 0 PRS_PLINK_5e.04 204 Leukemia Both 1 10 2 neoplasms darkcyan 10, 1 3, 0 2, 1 2, 0 3, 0 0.109 3.24 0.973 0.012 1.12 1.09 1.13 -0.21 2520 1 0 0.811 0.22 1.45 PRS_PLINK_5e.04 204.1 Lymphoid leukemia Both 0 5 2 neoplasms darkcyan 5, 0 2 1 1 1 PRS_PLINK_5e.04 204.11 Lymphoid leukemia, acute Both 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_5e.04 204.12 Lymphoid leukemia, chronic Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_5e.04 204.2 Myeloid leukemia Both 0 7 2 neoplasms darkcyan 7, 0 2 2 1 2 PRS_PLINK_5e.04 204.21 Myeloid leukemia, acute Both 0 4 2 neoplasms darkcyan 4, 0 1 1 1 1 PRS_PLINK_5e.04 204.4 Multiple myeloma Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_5e.04 208 Benign neoplasm of colon Both 24 38 2 neoplasms darkcyan 38, 24 9, 9 9, 6 9, 6 10, 3 -0.48 0.33 0.145 0.838 0.619 0.322 1.1 -1.83 1.17 0.118 0.928 0.161 0.00847 1.15 -0.375 0.838 0.654 0.184 0.687 0.148 2.87 -1.4 1.33 0.295 0.53 0.247 0.006 3.2 PRS_PLINK_5e.04 209 Neuroendocrine tumors Both 1 3 2 neoplasms darkcyan 3, 1 1, 0 1, 0 1, 1 1, 0 0.989 495000 1 0 2.69 8.43e-40 1.05e+31 -0.00433 84.7 1 0 0.996 0.96 1.16 PRS_PLINK_5e.04 210 Benign neoplasm of lip, oral cavity, and pharynx Both 2 17 2 neoplasms darkcyan 17, 2 5, 1 4, 0 4, 0 4, 1 0.0602 1.41 0.966 0.015 1.06 0.0198 387 -0.477 68 0.994 0.002 0.621 0.0159 0.548 -0.83 2.51 0.741 0.13 0.436 0.0105 20.2 -1.06 7.5 0.887 0.052 0.345 7.58e-06 47900 PRS_PLINK_5e.04 211 Benign neoplasm of other parts of digestive system Both 19 43 2 neoplasms darkcyan 43, 19 11, 8 11, 5 10, 1 11, 5 -0.365 0.344 0.29 0.538 0.695 0.347 1.28 -1.18 1.01 0.245 0.612 0.308 0.0355 1.74 -1.42 1.24 0.253 0.597 0.242 0.0169 1.96 -0.893 0.989 0.367 0.436 0.409 0.0551 2.27 PRS_PLINK_5e.04 212 Benign neoplasm of respiratory and intrathoracic organs Both 4 14 2 neoplasms darkcyan 14, 4 4, 2 3, 0 3, 1 4, 1 -0.211 0.753 0.779 0.108 0.809 0.194 9.24 -4.53 8.47 0.593 0.227 0.0108 0.00855 1.49 -1.02 5.48 0.853 0.069 0.362 0.335 0.399 -1.24 2.4 0.605 0.219 0.288 0.00142 9.82 PRS_PLINK_5e.04 213 Benign neoplasm of bone and articular cartilage Both 0 14 2 neoplasms darkcyan 14, 0 4 3 3 4 PRS_PLINK_5e.04 214 Lipoma Both 3 12 2 neoplasms darkcyan 12, 3 3, 1 3, 0 3, 0 3, 2 0.321 0.733 0.661 0.18 1.38 0.434 45.2 0.0115 1680 1 0 1.01 0.657 1.58 0.263 274 0.999 0 1.3 0.453 3.82 -0.181 15.5 0.991 0.004 0.835 0.812 16.3 PRS_PLINK_5e.04 214.1 Lipoma of skin and subcutaneous tissue Both 1 6 2 neoplasms darkcyan 6, 1 2, 1 1, 0 1, 0 2, 0 0.00539 1190 1 0 1.01 0.794 2.79 0.213 10700 1 0 1.24 0.102 5.93 0.0364 14300 1 0 1.04 0.511 2.03 -4.3e-05 2890 1 0 1 0.6 3.6 PRS_PLINK_5e.04 215 Other benign neoplasm of connective and other soft tissue Both 9 45 2 neoplasms darkcyan 45, 9 12, 2 11, 1 11, 4 11, 2 0.513 0.542 0.344 0.463 1.67 0.59 5.32 -0.314 1.67 0.851 0.07 0.731 0.00315 18.5 3.4 2.31 0.14 0.853 30 0.491 2.39e+08 1.25 1.42 0.378 0.422 3.49 0.263 154 PRS_PLINK_5e.04 216 Benign neoplasm of skin Both 20 44 2 neoplasms darkcyan 44, 20 10, 3 11, 8 11, 6 11, 3 -0.0701 0.344 0.838 0.077 0.932 0.475 1.79 0.285 0.998 0.776 0.11 1.33 0.199 9.26 0.493 0.969 0.611 0.214 1.64 0.315 10 -1.04 1.51 0.49 0.309 0.354 0.00121 63 PRS_PLINK_5e.04 216.1 Screening for malignant neoplasms of the skin Both 0 5 2 neoplasms darkcyan 5, 0 2 1 1 1 PRS_PLINK_5e.04 217 Vascular hamartomas and non-neoplastic nevi Both 1 16 2 neoplasms darkcyan 16, 1 4, 1 4, 0 4, 0 4, 0 -0.503 1.2 0.675 0.171 0.605 0.0124 12.1 0.127 1290 1 0 1.14 0.715 1.49 -1.44 51 0.978 0.01 0.238 0.0151 1.98 0.0145 25.5 1 0 1.01 0.52 0.162 PRS_PLINK_5e.04 217.1 Nevus, non-neoplastic Both 1 15 2 neoplasms darkcyan 15, 1 4, 1 4, 0 3, 0 4, 0 -0.39 1.16 0.737 0.132 0.677 0.0869 10.7 0.196 860 1 0 1.22 0.000197 3.11 -1.45 52.7 0.978 0.01 0.234 0.0105 3.91 0.0145 25.5 1 0 1.01 0.52 0.162 PRS_PLINK_5e.04 218 Benign neoplasm of uterus Female 10 18 2 neoplasms darkcyan 18, 10 5, 2 4, 4 4, 2 5, 2 0.112 0.577 0.847 0.072 1.12 0.406 3.62 -1.23 2.02 0.542 0.266 0.292 0.239 6.77 2.59 3.77 0.492 0.308 13.3 0.0368 17.8 1.34 3.09 0.664 0.178 3.84 0.00744 1460 PRS_PLINK_5e.04 218.1 Uterine leiomyoma Female 3 16 2 neoplasms darkcyan 16, 3 4, 1 4, 1 4, 1 4, 0 -0.621 0.823 0.451 0.346 0.538 0.0338 2.14 -0.551 4.77 0.908 0.042 0.576 0.553 0.608 -1.16 2.7 0.666 0.176 0.312 0.00265 11.6 -3.58 360 0.992 0.003 0.0279 3.69e-05 0.0486 PRS_PLINK_5e.04 218.2 Other benign neoplasm of uterus Female 10 17 2 neoplasms darkcyan 17, 10 5, 2 4, 4 4, 3 4, 1 0.185 0.619 0.765 0.116 1.2 0.41 3.89 -1.22 2.83 0.668 0.175 0.297 0.214 28.5 0.342 1.93 0.859 0.066 1.41 0.0202 180 0.266 1020 1 0 1.3 0.157 3.65e+12 PRS_PLINK_5e.04 220 Benign neoplasm of ovary Female 1 8 2 neoplasms darkcyan 8, 1 2, 1 2, 0 2, 0 2, 0 -0.928 2.46 0.706 0.151 0.395 0.375 0.416 -0.0795 3740 1 0 0.924 0.751 2.58 -0.146 564 1 0 0.864 0.302 2.08 -0.409 5210 1 0 0.664 0.604 3.42 PRS_PLINK_5e.04 221 Benign neoplasm of other female genital organs Female 5 13 2 neoplasms darkcyan 13, 5 4, 1 3, 2 3, 1 3, 1 -0.231 1.11 0.834 0.079 0.793 0.00858 5.1 -0.389 4.14 0.925 0.034 0.678 0.593 0.849 -0.0781 55.1 0.999 0 0.925 1.9e-09 1.27 1.79 6.76 0.791 0.102 5.99 4.62 7.63 PRS_PLINK_5e.04 222 Benign neoplasm of male genital organs Male 1 8 2 neoplasms darkcyan 8, 1 2, 0 2, 0 2, 1 2, 0 -0.851 1700000 1 0 0.427 0.297 0.754 -0.206 4740 1 0 0.814 0.337 2.64 PRS_PLINK_5e.04 223 Benign neoplasm of kidney and other urinary organs Both 2 7 2 neoplasms darkcyan 7, 2 2, 0 2, 0 1, 1 2, 1 -0.223 28.3 0.994 0.003 0.8 1.48 1.79 0.265 5260 1 0 1.3 0.617 5.01 -0.147 706 1 0 0.864 0.357 1.18 PRS_PLINK_5e.04 224 Benign neoplasm of eye Both 2 8 2 neoplasms darkcyan 8, 2 2, 0 2, 1 2, 0 2, 1 -0.38 25.9 0.988 0.005 0.684 0.225 0.876 -0.0463 4350 1 0 0.955 0.737 1.2 -0.386 5230 1 0 0.68 0.0484 73 PRS_PLINK_5e.04 224.1 Benign neoplasm of eye, uveal Both 2 10 2 neoplasms darkcyan 10, 2 3, 1 2, 0 2, 0 3, 1 0.213 1.76 0.904 0.044 1.24 0.064 44.2 0.139 4400 1 0 1.15 0.329 3.21 0.804 12300 1 0 2.23 0.317 76.4 -0.104 3110 1 0 0.901 0.0987 14.1 PRS_PLINK_5e.04 225 Benign neoplasm of brain and other parts of nervous system Both 0 13 2 neoplasms darkcyan 13, 0 4 3 3 3 PRS_PLINK_5e.04 225.1 Benign neoplasm of brain, cranial nerves, meninges Both 0 11 2 neoplasms darkcyan 11, 0 3 3 2 3 PRS_PLINK_5e.04 225.2 Benign neoplasm of spinal cord, meninges Both 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_5e.04 226 Benign neoplasm of thyroid glands Both 0 14 2 neoplasms darkcyan 14, 0 4 3 3 4 PRS_PLINK_5e.04 227 Benign neoplasm of other endocrine glands and related structures Both 0 16 2 neoplasms darkcyan 16, 0 4 4 4 4 PRS_PLINK_5e.04 227.1 Benign neoplasm of adrenal gland Both 0 5 2 neoplasms darkcyan 5, 0 2 1 1 1 PRS_PLINK_5e.04 227.2 Benign neoplasm of parathyroid gland Both 0 7 2 neoplasms darkcyan 7, 0 2 2 1 2 PRS_PLINK_5e.04 227.3 Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch) Both 0 4 2 neoplasms darkcyan 4, 0 1 1 1 1 PRS_PLINK_5e.04 228 Hemangioma and lymphangioma, any site Both 1 28 2 neoplasms darkcyan 28, 1 6, 0 7, 1 7, 0 7, 0 -0.173 0.683 0.8 0.097 0.841 0.076 10.4 0.625 2.35 0.791 0.102 1.87 0.0145 2110 PRS_PLINK_5e.04 228.1 Hemangioma of skin and subcutaneous tissue Both 1 16 2 neoplasms darkcyan 16, 1 3, 0 4, 1 4, 0 4, 0 -0.205 1 0.838 0.077 0.815 0.0101 4.62 0.0338 8.89 0.997 0.001 1.03 1.03 1.05 PRS_PLINK_5e.04 229 Benign neoplasm of unspecified sites Both 4 45 2 neoplasms darkcyan 45, 4 12, 1 11, 1 11, 1 11, 1 -0.0802 0.599 0.894 0.049 0.923 0.185 4.78 0.426 1.38 0.757 0.121 1.53 0.0237 54.8 0.182 1.33 0.891 0.05 1.2 0.0788 37.7 -0.348 1.48 0.814 0.089 0.706 0.00284 38.2 PRS_PLINK_5e.04 229.1 Benign neoplasm of lymph nodes Both 1 30 2 neoplasms darkcyan 30, 1 8, 0 7, 0 7, 0 8, 1 0.232 0.715 0.746 0.127 1.26 0.2 9.42 -0.12 2.33 0.959 0.018 0.887 0.0136 143 PRS_PLINK_5e.04 240 Simple and unspecified goiter Both 2 15 3 endocrine/metabolic brown 15, 2 4, 0 4, 0 3, 1 4, 1 0.298 1.15 0.796 0.099 1.35 0.101 24.7 0.00281 77600 1 0 1 0.00765 2.83 -0.103 66.1 0.999 0.001 0.902 0.209 3.36 PRS_PLINK_5e.04 241 Nontoxic nodular goiter Both 1 31 3 endocrine/metabolic brown 31, 1 8, 0 8, 0 7, 1 8, 0 -0.251 0.876 0.775 0.111 0.778 0.013 5.18 0.564 1.79 0.753 0.123 1.76 0.0525 357 PRS_PLINK_5e.04 241.1 Nontoxic uninodular goiter Both 0 30 3 endocrine/metabolic brown 30, 0 8 7 7 8 PRS_PLINK_5e.04 241.2 Nontoxic multinodular goiter Both 0 16 3 endocrine/metabolic brown 16, 0 4 4 4 4 PRS_PLINK_5e.04 242 Thyrotoxicosis with or without goiter Both 2 20 3 endocrine/metabolic brown 20, 2 5, 0 5, 0 5, 1 5, 1 0.552 1.32 0.675 0.17 1.74 0.104 893 0.344 2.88 0.905 0.043 1.41 0.000847 1190 0.329 3.59 0.927 0.033 1.39 0.00541 492 PRS_PLINK_5e.04 242.1 Graves' disease Both 1 9 3 endocrine/metabolic brown 9, 1 3, 0 2, 0 2, 1 2, 0 -0.0223 1030 1 0 0.978 0.646 1.45 0.0655 3190 1 0 1.07 0.587 1.13 PRS_PLINK_5e.04 242.2 Toxic multinodular goiter Both 0 2 3 endocrine/metabolic brown 2, 0 1 1 1 1 PRS_PLINK_5e.04 242.3 Exophthalmos Both 2 5 3 endocrine/metabolic brown 5, 2 2, 0 1, 1 1, 0 1, 1 0.142 3910 1 0 1.15 0.322 3.01 -0.000577 36.8 1 0 0.999 0.905 1.08 -0.0049 40.3 1 0 0.995 0.969 1.03 PRS_PLINK_5e.04 242.31 Thyrotoxic exophthalmos Both 1 2 3 endocrine/metabolic brown 2, 1 1, 0 1, 1 1, 0 1, 1 0.0674 7950 1 0 1.07 0.402 5.63 -9.52 45500000 1 0 7.34e-05 3.6e-38 1.57e+27 PRS_PLINK_5e.04 244 Hypothyroidism Both 11 44 3 endocrine/metabolic brown 44, 11 10, 0 11, 2 11, 4 11, 5 0.712 0.43 0.0977 1.01 2.04 0.965 4.82 1.51 1.45 0.297 0.527 4.52 0.359 416 1.47 1.35 0.274 0.563 4.36 0.434 3740 1.3 1.49 0.384 0.415 3.67 0.309 2850 PRS_PLINK_5e.04 244.1 Secondary hypothyroidism Both 2 28 3 endocrine/metabolic brown 28, 2 7, 0 7, 1 7, 0 7, 1 0.213 0.714 0.765 0.116 1.24 0.23 6.7 0.382 1.77 0.83 0.081 1.47 0.015 134 -0.196 1.89 0.917 0.038 0.822 0.0032 20.3 PRS_PLINK_5e.04 244.2 Acquired hypothyroidism Both 5 21 3 endocrine/metabolic brown 21, 5 6, 0 5, 0 5, 3 5, 2 1.76 1.1 0.107 0.969 5.83 1.02 1850 2.3 2.01 0.252 0.598 10 0.529 1420 2.37 2.62 0.366 0.437 10.7 0.199 3440 PRS_PLINK_5e.04 244.4 Hypothyroidism NOS Both 10 44 3 endocrine/metabolic brown 44, 10 10, 0 11, 2 11, 3 11, 5 0.872 0.469 0.0627 1.203 2.39 1.07 6.96 1.51 1.45 0.297 0.527 4.52 0.359 416 1.11 1.35 0.41 0.387 3.04 0.252 115 1.3 1.49 0.384 0.415 3.67 0.309 2850 PRS_PLINK_5e.04 245 Thyroiditis Both 1 16 3 endocrine/metabolic brown 16, 1 3, 0 4, 0 4, 1 4, 0 0.785 1.19 0.51 0.293 2.19 0.291 81 2.83 100 0.978 0.01 16.9 25.7 15100 PRS_PLINK_5e.04 245.2 Chronic thyroiditis Both 1 14 3 endocrine/metabolic brown 14, 1 3, 0 3, 0 3, 1 4, 0 1.22 1.55 0.431 0.365 3.39 0.348 316 1.1 6770000 1 0 3.01 1.9 9.17 PRS_PLINK_5e.04 245.21 Chronic lymphocytic thyroiditis Both 1 13 3 endocrine/metabolic brown 13, 1 3, 0 3, 0 3, 0 3, 1 1.33 1.68 0.429 0.367 3.78 0.358 1120 0.169 840 1 0 1.18 0.623 4.12 PRS_PLINK_5e.04 246 Other disorders of thyroid Both 8 40 3 endocrine/metabolic brown 40, 8 10, 1 10, 1 10, 3 10, 3 0.44 0.541 0.416 0.381 1.55 0.532 5.11 -0.0581 1.56 0.97 0.013 0.944 0.000261 16.4 0.619 1.21 0.61 0.215 1.86 0.114 58.1 0.471 1.3 0.717 0.145 1.6 0.127 27.1 PRS_PLINK_5e.04 246.2 Thyroid cyst Both 0 2 3 endocrine/metabolic brown 2, 0 1 1 1 1 PRS_PLINK_5e.04 246.7 Abnormal results of function study of thyroid Both 1 16 3 endocrine/metabolic brown 16, 1 4, 0 4, 0 4, 1 4, 0 0.0476 1.05 0.964 0.016 1.05 0.0431 7.44 3.46 180 0.985 0.007 31.7 25.3 45.5 PRS_PLINK_5e.04 249 Secondary diabetes mellitus Both 7 5 3 endocrine/metabolic brown 5, 7 2, 2 1, 3 1, 1 1, 1 -0.142 1.57 0.928 0.033 0.868 0.0331 17 -0.0754 4500 1 0 0.927 0.0435 10.6 -0.384 3690 1 0 0.681 0.00845 109 0.351 4250 1 0 1.42 0.433 1.56 PRS_PLINK_5e.04 250 Diabetes mellitus Both 32 29 3 endocrine/metabolic brown 29, 32 8, 4 7, 5 7, 10 7, 12 1.07 0.517 0.0385 1.415 2.91 1.21 11.5 1.87 1.72 0.275 0.56 6.51 0.251 1520 -0.000805 1.39 1 0 0.999 0.00421 42.7 2.04 1.31 0.118 0.927 7.71 0.885 418 PRS_PLINK_5e.04 250.1 Type 1 diabetes Both 29 8 3 endocrine/metabolic brown 8, 29 2, 4 2, 11 2, 2 2, 11 0.654 0.724 0.366 0.436 1.92 0.382 11 1.08 1.6 0.5 0.301 2.94 0.128 2410 -1.18e-12 109 1 0 1 2.33e-06 1.22 0.215 1.59 0.892 0.05 1.24 0.0265 135 PRS_PLINK_5e.04 250.11 Type 1 diabetes with ketoacidosis Both 6 1 3 endocrine/metabolic brown 1, 6 0.0961 7210000 1 0 1.1 0.383 4.15 PRS_PLINK_5e.04 250.12 Type 1 diabetes with renal manifestations Both 17 3 3 endocrine/metabolic brown 3, 17 1, 2 1, 0 0, 8 1, 6 0.5 0.796 0.529 0.276 1.65 0.0826 9.85 -0.536 6950 1 0 0.585 0.39 1.48 -0.124 3.34 0.97 0.013 0.883 0.000173 241 0.729 57.4 0.99 0.004 2.07 0.0274 124 PRS_PLINK_5e.04 250.13 Type 1 diabetes with ophthalmic manifestations Both 21 4 3 endocrine/metabolic brown 4, 21 1, 4 1, 0 1, 2 1, 15 0.391 0.866 0.652 0.186 1.48 0.18 207 -0.413 7160 1 0 0.662 0.57 4.47 0.338 188 0.999 0.001 1.4 0.394 6.79 0.557 1.58 0.724 0.14 1.75 0.00307 38.4 PRS_PLINK_5e.04 250.14 Type 1 diabetes with neurological manifestations Both 22 4 3 endocrine/metabolic brown 4, 22 1, 4 1, 5 1, 4 1, 9 0.372 0.783 0.635 0.197 1.45 0.196 12.3 -0.443 2.06 0.83 0.081 0.642 0.00892 23.9 -0.0095 14.9 0.999 0 0.991 0.111 8.63 0.214 1.69 0.899 0.046 1.24 0.0278 38.7 PRS_PLINK_5e.04 250.15 Diabetes type 1 with peripheral circulatory disorders Both 4 1 3 endocrine/metabolic brown 1, 4 2.59 71300 1 0 13.3 3.71e-05 8800000 PRS_PLINK_5e.04 250.2 Type 2 diabetes Both 30 26 3 endocrine/metabolic brown 26, 30 7, 5 6, 10 6, 3 7, 11 0.831 0.497 0.0944 1.025 2.29 0.952 8.27 0.341 1.49 0.819 0.087 1.41 0.0169 112 -0.604 1.86 0.745 0.128 0.547 0.00421 414 1.24 1.34 0.356 0.448 3.46 0.291 395 PRS_PLINK_5e.04 250.21 Type 2 diabetes with ketoacidosis Both 6 0 3 endocrine/metabolic brown 0, 6 PRS_PLINK_5e.04 250.22 Type 2 diabetes with renal manifestations Both 4 6 3 endocrine/metabolic brown 6, 4 2, 1 1, 2 1, 0 2, 1 -9.65e-13 5.47 1 0 1 0.0156 62.6 0.00906 633 1 0 1.01 0.66 5.35 3.33 5860 1 0 27.8 3.24e-07 4.29e+08 17.9 44300000 1 0 58400000 1.03e-20 9.18e+35 PRS_PLINK_5e.04 250.23 Type 2 diabetes with ophthalmic manifestations Both 19 7 3 endocrine/metabolic brown 7, 19 2, 4 2, 2 1, 9 2, 4 0.224 0.795 0.778 0.109 1.25 0.135 11.1 0.66 17.2 0.969 0.013 1.93 0.00318 1270 0.173 1.74 0.921 0.036 1.19 0.00349 209 0.861 14.5 0.953 0.021 2.37 7.07e-11 4.81e+11 PRS_PLINK_5e.04 250.24 Type 2 diabetes with neurological manifestations Both 18 10 3 endocrine/metabolic brown 10, 18 3, 3 2, 6 2, 2 3, 7 0.0113 0.737 0.988 0.005 1.01 0.173 8.61 -0.0341 2.1 0.987 0.006 0.966 0.00738 1120 2.05e-13 3.79 1 0 1 0.00336 320 0.276 1.61 0.864 0.064 1.32 0.0604 81.8 PRS_PLINK_5e.04 250.25 Diabetes type 2 with peripheral circulatory disorders Both 2 3 3 endocrine/metabolic brown 3, 2 1, 2 1, 0 1, 0 1, 2 -0.0136 1280 1 0 0.987 0.912 1.26 -0.0654 14000 1 0 0.937 0.0918 8.72 0.00867 1140 1 0 1.01 0.728 1.44 PRS_PLINK_5e.04 250.3 Insulin pump user Both 21 13 3 endocrine/metabolic brown 13, 21 4, 3 3, 10 3, 2 3, 5 0.449 0.502 0.371 0.431 1.57 0.659 4.86 0.918 1.76 0.602 0.22 2.5 0.0256 2280 0.734 5.05 0.884 0.053 2.08 1.87 2.29 1.64 1.9 0.388 0.411 5.17 0.274 462 PRS_PLINK_5e.04 250.4 Abnormal glucose Both 29 27 3 endocrine/metabolic brown 27, 29 7, 4 7, 5 6, 9 7, 10 0.69 0.602 0.252 0.598 1.99 0.55 8.44 0.506 1.22 0.678 0.169 1.66 0.134 257 0.195 1.42 0.891 0.05 1.22 0.0153 53.8 1.1 1.33 0.409 0.388 3.01 0.227 150 PRS_PLINK_5e.04 250.41 Impaired fasting glucose Both 8 15 3 endocrine/metabolic brown 15, 8 4, 2 4, 3 3, 1 4, 2 0.632 0.778 0.417 0.38 1.88 0.268 15.7 -0.417 6.18 0.946 0.024 0.659 3.3e-06 254000 -1.01e-11 48 1 0 1 0.0206 1.06 1.11 4.04 0.784 0.106 3.02 0.00568 4040 PRS_PLINK_5e.04 250.42 Other abnormal glucose Both 29 27 3 endocrine/metabolic brown 27, 29 7, 4 7, 5 6, 9 7, 10 0.69 0.602 0.252 0.598 1.99 0.55 8.44 0.506 1.22 0.678 0.169 1.66 0.134 257 0.195 1.42 0.891 0.05 1.22 0.0153 53.8 1.1 1.33 0.409 0.388 3.01 0.227 150 PRS_PLINK_5e.04 250.6 Polyneuropathy in diabetes Both 22 7 3 endocrine/metabolic brown 7, 22 2, 4 2, 9 1, 2 2, 7 0.283 0.746 0.704 0.152 1.33 0.213 21.3 -0.0563 1.65 0.973 0.012 0.945 0.00321 41.2 -0.000535 3.04 1 0 0.999 0.345 2.71 0.352 1.49 0.813 0.09 1.42 0.0737 46.7 PRS_PLINK_5e.04 250.7 Diabetic retinopathy Both 21 10 3 endocrine/metabolic brown 10, 21 2, 4 2, 11 2, 1 3, 5 -0.0443 0.506 0.93 0.031 0.957 0.381 2.4 -0.377 1.52 0.804 0.095 0.686 0.00601 31.8 0.0206 5.66 0.997 0.001 1.02 0.0419 21.8 -0.154 1.73 0.929 0.032 0.857 0.0178 27 PRS_PLINK_5e.04 251 Other disorders of pancreatic internal secretion Both 10 16 3 endocrine/metabolic brown 16, 10 3, 1 4, 3 4, 1 4, 5 0.967 0.724 0.182 0.74 2.63 0.784 17.1 2.06 2.41 0.392 0.407 7.86 0.256 53300 0.0456 412 1 0 1.05 0.785 1.31 -0.406 2.27 0.858 0.066 0.667 0.615 0.739 PRS_PLINK_5e.04 251.1 Hypoglycemia Both 11 5 3 endocrine/metabolic brown 5, 11 2, 5 1, 0 1, 0 1, 6 0.832 1.18 0.482 0.317 2.3 0.287 21.8 -0.0318 2630 1 0 0.969 0.195 2.25 -0.0334 1140 1 0 0.967 0.283 1.61 0.791 1.66 0.634 0.198 2.2 0.0139 51.2 PRS_PLINK_5e.04 252 Disorders of parathyroid gland Both 2 21 3 endocrine/metabolic brown 21, 2 6, 0 5, 1 5, 0 5, 1 0.233 1.07 0.827 0.082 1.26 0.0381 92.8 -0.0221 2.9 0.994 0.003 0.978 0.00084 165000 -0.0676 3.53 0.985 0.007 0.935 0.00236 212 PRS_PLINK_5e.04 252.1 Hyperparathyroidism Both 2 21 3 endocrine/metabolic brown 21, 2 6, 0 5, 1 5, 0 5, 1 0.233 1.07 0.827 0.082 1.26 0.0381 92.8 -0.0221 2.9 0.994 0.003 0.978 0.00084 165000 -0.0676 3.53 0.985 0.007 0.935 0.00236 212 PRS_PLINK_5e.04 252.2 Hypoparathyroidism Both 0 5 3 endocrine/metabolic brown 5, 0 2 1 1 1 PRS_PLINK_5e.04 253 Disorders of the pituitary gland and its hypothalamic control Both 2 14 3 endocrine/metabolic brown 14, 2 4, 1 3, 0 3, 0 4, 1 -0.593 1.5 0.693 0.159 0.553 0.0132 14.2 -0.0315 6.67 0.996 0.002 0.969 0.408 1.76 5.9e-14 8.52 1 0 1 0.945 24.8 1.81 224 0.994 0.003 6.12 5.44 6.87 PRS_PLINK_5e.04 253.1 Pituitary hyperfunction Both 0 6 3 endocrine/metabolic brown 6, 0 2 1 1 2 PRS_PLINK_5e.04 253.11 Acromegaly and gigantism Both 0 1 3 endocrine/metabolic brown 1, 0 PRS_PLINK_5e.04 253.2 Pituitary hypofunction Both 1 7 3 endocrine/metabolic brown 7, 1 2, 0 2, 0 1, 0 2, 1 0.0389 313 1 0 1.04 0.901 1.39 0.541 7060 1 0 1.72 0.338 3.44 PRS_PLINK_5e.04 253.3 Diabetes insipidus Both 0 3 3 endocrine/metabolic brown 3, 0 1 1 1 1 PRS_PLINK_5e.04 253.4 Anterior pituitary disorders Both 0 4 3 endocrine/metabolic brown 4, 0 1 1 1 1 PRS_PLINK_5e.04 253.7 Other disorders of neurohypophysis Both 0 2 3 endocrine/metabolic brown 2, 0 1 1 1 1 PRS_PLINK_5e.04 255 Disorders of adrenal glands Both 0 20 3 endocrine/metabolic brown 20, 0 5 5 5 5 PRS_PLINK_5e.04 255.1 Adrenal hyperfunction Both 0 3 3 endocrine/metabolic brown 3, 0 1 1 1 1 PRS_PLINK_5e.04 255.11 Cushing's syndrome Both 0 1 3 endocrine/metabolic brown 1, 0 PRS_PLINK_5e.04 255.12 Hyperaldosteronism Both 0 1 3 endocrine/metabolic brown 1, 0 PRS_PLINK_5e.04 255.2 Adrenal hypofunction Both 0 7 3 endocrine/metabolic brown 7, 0 2 2 1 2 PRS_PLINK_5e.04 255.21 Glucocorticoid deficiency Both 0 7 3 endocrine/metabolic brown 7, 0 2 2 1 2 PRS_PLINK_5e.04 256 Ovarian dysfunction Female 2 11 3 endocrine/metabolic brown 11, 2 3, 1 3, 1 2, 0 3, 0 -0.652 1.21 0.591 0.228 0.521 0.04 3.49 0.0198 114 1 0 1.02 0.000396 5.75 -0.119 238 1 0 0.888 0.215 1.75 0.13 598 1 0 1.14 0.641 2.15 PRS_PLINK_5e.04 256.4 Polycystic ovaries Female 1 6 3 endocrine/metabolic brown 6, 1 2, 1 1, 0 1, 0 2, 0 -0.437 739 1 0 0.646 0.181 0.422 -0.413 8370000 1 0 0.661 0.0453 8.01 0.261 2390 1 0 1.3 0.481 6.12 0.47 4590 1 0 1.6 0.015 151 PRS_PLINK_5e.04 257 Testicular dysfunction Male 5 10 3 endocrine/metabolic brown 10, 5 3, 0 2, 1 2, 0 3, 4 2.26 1.86 0.225 0.647 9.55 0.39 677 0.00356 322 1 0 1 0.97 1.07 0.114 7.96 0.989 0.005 1.12 1.02 1.26 PRS_PLINK_5e.04 257.1 Testicular hypofunction Male 5 11 3 endocrine/metabolic brown 11, 5 3, 0 3, 1 2, 2 3, 2 1.95 1.63 0.232 0.635 7 0.649 194 -0.00339 828 1 0 0.997 0.858 1.08 -0.62 6460 1 0 0.538 0.263 2.23 2.19 82.6 0.979 0.009 8.95 3.49 51 PRS_PLINK_5e.04 258 Iatrogenic endocrine disorders Both 0 1 3 endocrine/metabolic brown 1, 0 PRS_PLINK_5e.04 259 Other endocrine disorders Both 2 15 3 endocrine/metabolic brown 15, 2 4, 0 4, 0 3, 1 4, 1 1.05 1.3 0.422 0.375 2.84 0.399 219 -0.11 4110 1 0 0.896 0.275 2.02 0.0282 1120 1 0 1.03 0.924 1.73 PRS_PLINK_5e.04 260 Protein-calorie malnutrition Both 2 22 3 endocrine/metabolic brown 22, 2 6, 2 5, 0 5, 0 6, 0 -0.386 0.843 0.648 0.189 0.68 0.0694 4.03 0.122 2.08 0.953 0.021 1.13 0.000133 159 -0.927 2.34 0.691 0.16 0.396 0.000747 53.9 -1.04 2.78 0.709 0.149 0.355 5.31e-05 95.2 PRS_PLINK_5e.04 260.2 severe protein-calorie malnutrition Both 1 12 3 endocrine/metabolic brown 12, 1 3, 1 3, 0 3, 0 3, 0 -0.726 1.56 0.642 0.193 0.484 0.0179 6.72 0.0265 233 1 0 1.03 0.356 4.15 0.25 137 0.999 0.001 1.28 0.0362 72.2 0.281 863 1 0 1.32 0.552 3.08 PRS_PLINK_5e.04 260.22 Nutritional marasmus Both 1 4 3 endocrine/metabolic brown 4, 1 1, 1 1, 0 1, 0 1, 0 0.128 3690 1 0 1.14 0.341 1.35 0.00166 260 1 0 1 0.976 1.03 0.0212 83.2 1 0 1.02 0.975 1.03 -0.00104 52 1 0 0.999 0.989 1.01 PRS_PLINK_5e.04 260.3 Adult failure to thrive Both 1 3 3 endocrine/metabolic brown 3, 1 1, 1 1, 0 1, 0 1, 1 -0.00172 4130 1 0 0.998 0.252 4.73 -1.25 7630000 1 0 0.287 6.15e-09 13300000 -1.25 7220000 1 0 0.287 6.15e-09 13300000 PRS_PLINK_5e.04 260.6 Anorexia Both 1 4 3 endocrine/metabolic brown 4, 1 1, 0 1, 1 1, 0 1, 0 -0.789 8800 1 0 0.454 4.89e-06 10800 -0.00652 58 1 0 0.993 0.925 1.06 PRS_PLINK_5e.04 260.7 Polyphagia Both 0 2 3 endocrine/metabolic brown 2, 0 1 1 1 1 PRS_PLINK_5e.04 261 Vitamin deficiency Both 20 37 3 endocrine/metabolic brown 37, 20 9, 6 9, 5 9, 3 9, 6 0.253 0.307 0.41 0.387 1.29 0.738 2.27 -0.353 1 0.725 0.14 0.702 0.105 4.21 -1.03 1.22 0.4 0.398 0.358 0.0212 3.07 0.082 0.864 0.924 0.034 1.09 0.241 4.91 PRS_PLINK_5e.04 261.1 Vitamin A deficiency Both 2 0 3 endocrine/metabolic brown 0, 2 PRS_PLINK_5e.04 261.2 Vitamin B-complex deficiencies Both 1 7 3 endocrine/metabolic brown 7, 1 2, 1 2, 0 1, 0 2, 0 -1.24 182 0.995 0.002 0.291 0.00588 7.73 -0.103 2780 1 0 0.902 0.361 1.84 0.912 24500 1 0 2.49 0.0467 163 0.0456 2710 1 0 1.05 0.504 2.04 PRS_PLINK_5e.04 261.4 Vitamin D deficiency Both 20 36 3 endocrine/metabolic brown 36, 20 8, 6 9, 6 9, 2 9, 6 0.229 0.308 0.457 0.341 1.26 0.719 2.23 -0.428 1 0.669 0.175 0.652 0.0978 3.97 -1.31 1.29 0.307 0.513 0.269 0.0121 2.48 -0.0184 0.897 0.984 0.007 0.982 0.205 4.58 PRS_PLINK_5e.04 262 Mineral deficiency NEC Both 7 13 3 endocrine/metabolic brown 13, 7 4, 5 3, 0 3, 0 3, 2 -2.75 2.54 0.279 0.554 0.0637 0.0426 3.48 -1.48 2.03 0.464 0.333 0.227 0.00371 6.53 1.93 6.24 0.757 0.121 6.91 5.02e-07 289000 -0.569 4.34 0.896 0.048 0.566 2.12e-06 911 PRS_PLINK_5e.04 263 Other nutritional deficiency Both 4 19 3 endocrine/metabolic brown 19, 4 4, 0 5, 1 4, 1 5, 2 0.471 0.675 0.486 0.314 1.6 0.548 7.67 0.136 2.85 0.962 0.017 1.15 0.00731 100 0.193 76.9 0.998 0.001 1.21 0.95 5.21 0.367 2.2 0.867 0.062 1.44 0.00184 1270 PRS_PLINK_5e.04 264 Lack of normal physiological development Both 1 2 3 endocrine/metabolic brown 2, 1 1, 0 0, 1 1, 0 1, 0 -0.00136 204 1 0 0.999 0.989 1.01 -0.000538 430 1 0 0.999 0.99 1.02 PRS_PLINK_5e.04 264.2 Failure to thrive (childhood) Both 1 4 3 endocrine/metabolic brown 4, 1 1, 1 1, 0 1, 0 1, 1 0.26 3850 1 0 1.3 0.522 5.13 PRS_PLINK_5e.04 264.9 Lack of normal physiological development, unspecified Both 1 1 3 endocrine/metabolic brown 1, 1 -0.00423 93.2 1 0 0.996 0.869 2.9 PRS_PLINK_5e.04 269 Proteinuria Both 9 30 3 endocrine/metabolic brown 30, 9 8, 0 7, 4 7, 2 8, 2 -0.153 0.452 0.735 0.134 0.858 0.35 1.86 1.58 1.57 0.314 0.504 4.86 0.371 1440 1.35 1.91 0.477 0.321 3.88 0.0408 15100 0.261 2.25 0.907 0.042 1.3 2.92e-05 7420 PRS_PLINK_5e.04 270 Disorders of protein plasma/amino-acid transport and metabolism Both 4 10 3 endocrine/metabolic brown 10, 4 3, 1 2, 1 2, 0 3, 2 0.668 2.58 0.796 0.099 1.95 0.0182 324 0.427 2310 1 0 1.53 0.488 4.71 -0.905 4220 1 0 0.405 0.0179 8.44 -0.839 99.8 0.993 0.003 0.432 3.36e-08 5570000 PRS_PLINK_5e.04 270.1 Disturbances of amino-acid transport Both 1 1 3 endocrine/metabolic brown 1, 1 0.00181 181 1 0 1 0.952 1.03 PRS_PLINK_5e.04 270.11 Disturbances of sulphur-bearing amino-acid metabolism Both 1 0 3 endocrine/metabolic brown 0, 1 PRS_PLINK_5e.04 270.2 Disorders of amino-acid metabolism Both 0 4 3 endocrine/metabolic brown 4, 0 1 1 1 1 PRS_PLINK_5e.04 270.3 Disorders of plasma protein metabolism Both 3 10 3 endocrine/metabolic brown 10, 3 3, 0 2, 0 2, 1 3, 2 -0.0869 2.79 0.975 0.011 0.917 0.00861 1300 -0.256 6580 1 0 0.774 0.126 1.63 0.559 3450 1 0 1.75 0.861 2.14 PRS_PLINK_5e.04 270.32 Paraproteinemia Both 2 6 3 endocrine/metabolic brown 6, 2 2, 0 1, 0 1, 0 2, 2 0.091 462 1 0 1.1 0.848 1.29 0.395 15200 1 0 1.49 0.0581 1.61 PRS_PLINK_5e.04 270.34 Alpha-1-antitrypsin deficiency Both 0 3 3 endocrine/metabolic brown 3, 0 1 1 1 1 PRS_PLINK_5e.04 270.38 Other specified disorders of plasma protein metabolism Both 1 5 3 endocrine/metabolic brown 5, 1 2, 1 1, 0 1, 0 1, 0 1.38 45200000 1 0 3.97 0.000193 9070 0.00188 28.2 1 0 1 0.93 1.62 0.00316 43.5 1 0 1 0.913 1.09 -0.0193 53.2 1 0 0.981 0.753 3.97 PRS_PLINK_5e.04 271 Disorders of carbohydrate transport and metabolism Both 2 36 3 endocrine/metabolic brown 36, 2 9, 0 9, 1 9, 0 9, 1 0.422 0.522 0.419 0.378 1.53 0.432 5.03 0.101 1.66 0.951 0.022 1.11 0.0231 109 0.527 1.38 0.703 0.153 1.69 0.0908 37.8 PRS_PLINK_5e.04 271.3 Intestinal disaccharidase deficiencies and disaccharide malabsorption Both 1 33 3 endocrine/metabolic brown 33, 1 9, 0 8, 0 8, 1 8, 0 0.211 0.622 0.735 0.134 1.23 0.183 8.46 0.566 1.45 0.696 0.157 1.76 0.0989 55.1 PRS_PLINK_5e.04 271.9 Other disorders of carbohydrate transport and metabolism Both 1 3 3 endocrine/metabolic brown 3, 1 1, 0 1, 0 1, 1 1, 0 -0.142 1950 1 0 0.867 0.384 2.46 -0.0139 61.7 1 0 0.986 0.86 1.19 PRS_PLINK_5e.04 272 Disorders of lipoid metabolism Both 33 28 3 endocrine/metabolic brown 28, 33 7, 6 7, 6 7, 8 7, 12 0.364 0.334 0.276 0.56 1.44 0.781 2.72 -1.27 1.26 0.315 0.502 0.281 0.0135 2.29 -4.22 2.53 0.0954 1.02 0.0147 3.21e-05 0.991 1.03 1.13 0.361 0.443 2.8 0.377 44.5 PRS_PLINK_5e.04 272.1 Hyperlipidemia Both 33 28 3 endocrine/metabolic brown 28, 33 7, 6 7, 6 7, 8 7, 12 0.364 0.334 0.276 0.56 1.44 0.781 2.72 -1.27 1.26 0.315 0.502 0.281 0.0135 2.29 -4.22 2.53 0.0954 1.02 0.0147 3.21e-05 0.991 1.03 1.13 0.361 0.443 2.8 0.377 44.5 PRS_PLINK_5e.04 272.11 Hypercholesterolemia Both 16 19 3 endocrine/metabolic brown 19, 16 5, 4 5, 5 4, 2 5, 5 0.00191 0.545 0.997 0.001 1 0.378 2.65 -2.29 1.8 0.205 0.688 0.102 0.00313 1.9 -1.7 2.44 0.485 0.314 0.182 0.0123 8.77 -1.07 2.31 0.645 0.191 0.345 0.000522 20.1 PRS_PLINK_5e.04 272.12 Hyperglyceridemia Both 5 7 3 endocrine/metabolic brown 7, 5 2, 1 2, 1 1, 1 2, 1 -0.943 1.58 0.551 0.259 0.389 0.00356 4.18 0.375 2080 1 0 1.46 0.00381 121 -0.0297 418 1 0 0.971 0.501 1.18 -1.55 310 0.996 0.002 0.213 2.53e-07 1350000 PRS_PLINK_5e.04 272.13 Mixed hyperlipidemia Both 14 17 3 endocrine/metabolic brown 17, 14 5, 2 4, 7 4, 1 4, 4 -0.0306 0.635 0.962 0.017 0.97 0.263 3.04 -0.516 1.97 0.793 0.101 0.597 0.0068 16.8 -1.02 3.15 0.745 0.128 0.359 0.000473 31.4 0.805 2.17 0.71 0.148 2.24 0.0319 2780 PRS_PLINK_5e.04 272.9 Unspecified disorder of lipoid metabolism Both 0 3 3 endocrine/metabolic brown 3, 0 1 1 1 1 PRS_PLINK_5e.04 274 Gout and other crystal arthropathies Both 2 27 3 endocrine/metabolic brown 27, 2 7, 1 7, 0 6, 0 7, 1 0.265 0.75 0.724 0.14 1.3 0.181 25.3 0.242 1.88 0.898 0.047 1.27 0.0135 1060 -0.79 1.94 0.683 0.165 0.454 0.00317 86.5 -0.894 2.04 0.661 0.18 0.409 0.00155 2390 PRS_PLINK_5e.04 274.1 Gout Both 2 27 3 endocrine/metabolic brown 27, 2 7, 1 7, 0 6, 0 7, 1 0.265 0.75 0.724 0.14 1.3 0.181 25.3 0.242 1.88 0.898 0.047 1.27 0.0135 1060 -0.79 1.94 0.683 0.165 0.454 0.00317 86.5 -0.894 2.04 0.661 0.18 0.409 0.00155 2390 PRS_PLINK_5e.04 274.11 Gouty arthropathy Both 1 21 3 endocrine/metabolic brown 21, 1 6, 0 5, 0 5, 0 5, 1 -0.192 1.06 0.856 0.067 0.825 0.00876 12.8 0.385 6.94 0.956 0.02 1.47 0.00101 3400 PRS_PLINK_5e.04 274.2 Crystal arthropathies Both 0 2 3 endocrine/metabolic brown 2, 0 1 1 1 1 PRS_PLINK_5e.04 274.21 Chondrocalcinosis Both 0 2 3 endocrine/metabolic brown 2, 0 1 1 1 1 PRS_PLINK_5e.04 275 Disorders of mineral metabolism Both 7 47 3 endocrine/metabolic brown 47, 7 12, 1 12, 2 11, 0 12, 3 -0.773 0.521 0.138 0.861 0.462 0.101 1.21 1.09 1.39 0.433 0.363 2.97 0.133 65.6 -0.368 1.33 0.782 0.107 0.692 0.0188 16.6 -0.103 1.26 0.935 0.029 0.902 0.0157 11.8 PRS_PLINK_5e.04 275.1 Disorders of iron metabolism Both 0 4 4 hematopoietic darkorange1 4, 0 1 1 1 1 PRS_PLINK_5e.04 275.11 Hereditary hemochromatosis Both 0 3 4 hematopoietic darkorange1 3, 0 1 1 1 1 PRS_PLINK_5e.04 275.2 Disorders of copper metabolism Both 0 2 3 endocrine/metabolic brown 2, 0 1 1 1 1 PRS_PLINK_5e.04 275.3 Disorders of magnesium metabolism Both 2 19 3 endocrine/metabolic brown 19, 2 5, 1 5, 0 4, 0 5, 1 0.154 0.937 0.87 0.061 1.17 0.084 61.9 1.3 6.87 0.85 0.071 3.67 5.21e-05 36100 0.0916 3 0.976 0.011 1.1 0.00833 723 -1.88 4.71 0.689 0.162 0.152 6.27e-05 138 PRS_PLINK_5e.04 275.5 Disorders of calcium/phosphorus metabolism Both 4 40 3 endocrine/metabolic brown 40, 4 10, 1 10, 1 10, 0 10, 1 -1.24 0.737 0.0932 1.031 0.29 0.00478 1.08 0.719 1.9 0.705 0.152 2.05 0.0434 192 -0.262 1.57 0.868 0.062 0.77 0.00522 17.7 -0.656 1.8 0.715 0.145 0.519 0.00036 13.5 PRS_PLINK_5e.04 275.51 Hypocalcemia Both 0 9 3 endocrine/metabolic brown 9, 0 3 2 2 2 PRS_PLINK_5e.04 275.53 Disorders of phosphorus metabolism Both 1 14 3 endocrine/metabolic brown 14, 1 4, 1 3, 0 3, 0 4, 0 -0.392 0.942 0.677 0.169 0.676 0.0171 3.24 -4.93 66.7 0.941 0.026 0.00724 0.00668 1.15 -2.29 372 0.995 0.002 0.102 0.0114 0.196 -2.72 159 0.986 0.006 0.066 0.0024 0.319 PRS_PLINK_5e.04 275.6 Hypercalcemia Both 4 27 3 endocrine/metabolic brown 27, 4 7, 1 7, 0 6, 0 7, 2 -0.474 0.637 0.456 0.341 0.622 0.0265 2.03 -0.133 2.03 0.948 0.023 0.875 0.000101 486 -0.0725 2.02 0.971 0.013 0.93 0.0111 44.8 0.307 1.96 0.876 0.058 1.36 0.000972 10400 PRS_PLINK_5e.04 276 Disorders of fluid, electrolyte, and acid-base balance Both 15 47 3 endocrine/metabolic brown 47, 15 11, 5 12, 7 11, 0 12, 3 -0.394 0.362 0.277 0.558 0.674 0.321 1.28 -0.0199 0.845 0.981 0.008 0.98 0.205 4.47 -2.28 1.59 0.151 0.82 0.102 0.000884 1.38 -0.711 1 0.479 0.32 0.491 0.0701 2.59 PRS_PLINK_5e.04 276.1 Electrolyte imbalance Both 11 40 3 endocrine/metabolic brown 40, 11 9, 5 10, 4 10, 0 10, 2 -0.541 0.448 0.227 0.644 0.582 0.223 1.28 -0.995 1.08 0.358 0.447 0.37 0.0437 2.32 -1.79 1.4 0.203 0.693 0.168 5.8e-06 1.64 -0.698 1.14 0.541 0.267 0.497 0.0569 3.25 PRS_PLINK_5e.04 276.11 Hyperosmolality and/or hypernatremia Both 0 7 3 endocrine/metabolic brown 7, 0 2 2 1 2 PRS_PLINK_5e.04 276.12 Hyposmolality and/or hyponatremia Both 4 25 3 endocrine/metabolic brown 25, 4 6, 2 6, 2 6, 0 6, 0 -1.24 0.841 0.142 0.849 0.29 0.00212 1.26 -0.355 2.73 0.896 0.048 0.701 0.000162 48.1 -0.15 2.16 0.945 0.025 0.861 0.00139 71.7 -0.0832 2.93 0.977 0.01 0.92 0.000121 165 PRS_PLINK_5e.04 276.13 Hyperpotassemia Both 3 27 3 endocrine/metabolic brown 27, 3 6, 1 7, 1 6, 0 7, 1 -0.0696 0.685 0.919 0.037 0.933 0.125 4.01 -0.585 1.86 0.754 0.123 0.557 0.000441 36.9 -0.451 1.53 0.768 0.114 0.637 0.0412 8.89 -0.276 1.73 0.873 0.059 0.759 0.00437 115 PRS_PLINK_5e.04 276.14 Hypopotassemia Both 2 29 3 endocrine/metabolic brown 29, 2 7, 1 7, 1 7, 0 7, 0 -0.462 0.746 0.535 0.271 0.63 0.0456 2.78 3.8 3.67 0.301 0.522 44.7 0.0957 588000 -0.662 1.74 0.704 0.152 0.516 0.00875 11.4 0.52 2.31 0.822 0.085 1.68 0.0186 291 PRS_PLINK_5e.04 276.4 Acid-base balance disorder Both 2 22 3 endocrine/metabolic brown 22, 2 5, 2 5, 0 5, 0 6, 0 -0.72 1.05 0.494 0.306 0.487 0.000337 4.98 -2.18 2.63 0.408 0.39 0.113 1.19e-05 5.06 -0.785 2.04 0.7 0.155 0.456 0.0125 11.7 1.08 3.08 0.727 0.139 2.93 0.00612 5270 PRS_PLINK_5e.04 276.41 Acidosis Both 2 20 3 endocrine/metabolic brown 20, 2 4, 2 5, 0 5, 0 5, 0 -1.01 0.984 0.305 0.515 0.364 0.000983 2.05 -1.4 2.69 0.602 0.22 0.246 0.000708 14 -0.718 1.63 0.66 0.181 0.488 0.0304 9.79 -0.925 1.57 0.556 0.255 0.396 0.0386 3.82 PRS_PLINK_5e.04 276.42 Alkalosis Both 0 6 3 endocrine/metabolic brown 6, 0 2 1 1 2 PRS_PLINK_5e.04 276.5 Hypovolemia Both 6 39 3 endocrine/metabolic brown 39, 6 9, 5 10, 0 9, 0 10, 1 -0.152 0.501 0.762 0.118 0.859 0.269 2.25 -2.89 1.79 0.106 0.974 0.0556 3.92e-09 1.11 -2.06 2.06 0.318 0.498 0.128 0.0837 6.34 -0.77 1.24 0.533 0.273 0.463 0.0451 3.61 PRS_PLINK_5e.04 276.6 Fluid overload Both 0 16 3 endocrine/metabolic brown 16, 0 4 4 4 4 PRS_PLINK_5e.04 276.8 Polydipsia Both 0 3 3 endocrine/metabolic brown 3, 0 1 1 1 1 PRS_PLINK_5e.04 277 Other disorders of metabolism Both 9 43 3 endocrine/metabolic brown 43, 9 10, 1 11, 1 10, 3 11, 4 0.524 0.44 0.233 0.632 1.69 0.765 4.09 0.502 1.71 0.769 0.114 1.65 0.0228 52.3 2.2 2.26 0.33 0.481 9.02 0.236 6.54e+10 1.38 1.43 0.332 0.479 3.99 0.372 201 PRS_PLINK_5e.04 277.2 Other disorders of purine and pyrimidine metabolism Both 0 18 3 endocrine/metabolic brown 18, 0 5 4 4 5 PRS_PLINK_5e.04 277.4 Disorders of bilirubin excretion Both 1 13 3 endocrine/metabolic brown 13, 1 4, 1 3, 0 3, 0 3, 0 -0.189 1.33 0.887 0.052 0.828 0.0239 76.5 -0.176 1450 1 0 0.838 0.606 2.65 -0.336 1350000 1 0 0.715 0.443 1.23 -0.0113 429 1 0 0.989 0.674 1.48 PRS_PLINK_5e.04 277.5 Other disorders of lipoid metabolism Both 2 21 3 endocrine/metabolic brown 21, 2 5, 1 5, 0 5, 0 5, 1 0.436 0.844 0.605 0.218 1.55 0.0938 11.6 0.296 2.2 0.893 0.049 1.34 0.045 275 3.91 11.6 0.735 0.134 50 39.3 63.6 0.489 1.76 0.781 0.107 1.63 0.044 38.7 PRS_PLINK_5e.04 277.51 Lipoprotein disorders Both 0 16 3 endocrine/metabolic brown 16, 0 4 4 4 4 PRS_PLINK_5e.04 277.7 Dysmetabolic syndrome X Both 4 24 3 endocrine/metabolic brown 24, 4 6, 0 6, 0 6, 1 6, 3 0.12 0.879 0.891 0.05 1.13 0.0562 7.51 0.1 1.74 0.954 0.02 1.11 0.0295 109 0.238 2.32 0.918 0.037 1.27 0.00939 784 PRS_PLINK_5e.04 278 Overweight, obesity and other hyperalimentation Both 22 42 3 endocrine/metabolic brown 42, 22 10, 4 10, 4 10, 8 11, 6 0.305 0.317 0.335 0.475 1.36 0.765 2.49 0.036 1.23 0.977 0.01 1.04 0.00763 9.5 1.3 1.04 0.213 0.672 3.67 0.652 50.7 1.61 1.23 0.192 0.717 5 0.541 152 PRS_PLINK_5e.04 278.1 Obesity Both 20 42 3 endocrine/metabolic brown 42, 20 10, 4 10, 4 10, 6 11, 6 0.293 0.317 0.355 0.45 1.34 0.753 2.45 0.036 1.23 0.977 0.01 1.04 0.00763 9.5 1.13 1.09 0.301 0.522 3.09 0.495 45.2 1.61 1.23 0.192 0.717 5 0.541 152 PRS_PLINK_5e.04 278.11 Morbid obesity Both 6 38 3 endocrine/metabolic brown 38, 6 9, 2 9, 2 9, 0 10, 2 -0.806 0.753 0.285 0.546 0.447 0.00764 1.91 0.167 1.33 0.9 0.046 1.18 0.00731 21 -0.371 1.37 0.787 0.104 0.69 0.000621 21.6 -0.246 1.32 0.852 0.07 0.782 1.07e-05 12 PRS_PLINK_5e.04 278.3 Localized adiposity Both 0 8 3 endocrine/metabolic brown 8, 0 2 2 2 2 PRS_PLINK_5e.04 278.4 Abnormal weight gain Both 2 36 3 endocrine/metabolic brown 36, 2 8, 0 9, 0 9, 0 9, 2 1.46 0.963 0.129 0.889 4.31 0.654 449 1.24 1.69 0.461 0.336 3.47 0.191 2190 PRS_PLINK_5e.04 279 Disorders involving the immune mechanism Both 7 37 3 endocrine/metabolic brown 37, 7 9, 1 9, 3 9, 1 9, 2 0.02 0.429 0.963 0.016 1.02 0.436 2.35 0.151 2 0.94 0.027 1.16 0.00242 275000 -0.709 1.92 0.712 0.148 0.492 2.07e-05 39.3 1.33 1.49 0.372 0.429 3.78 0.333 1000 PRS_PLINK_5e.04 279.1 Immunity deficiency Both 3 15 3 endocrine/metabolic brown 15, 3 3, 0 4, 0 3, 1 4, 2 0.263 0.73 0.719 0.143 1.3 0.308 136 0.196 803 1 0 1.22 0.394 4.96 0.0791 1170 1 0 1.08 0.425 4.65 PRS_PLINK_5e.04 279.11 Deficiency of humoral immunity Both 2 6 3 endocrine/metabolic brown 6, 2 2, 0 1, 0 1, 0 2, 2 0.806 301 0.998 0.001 2.24 1.7 3.95 0.362 1860 1 0 1.44 0.434 5 PRS_PLINK_5e.04 279.2 Autoimmune disease NEC Both 3 12 3 endocrine/metabolic brown 12, 3 3, 1 3, 1 3, 0 3, 1 0.576 1.26 0.648 0.189 1.78 0.0308 70 -0.0503 64 0.999 0 0.951 0.643 1.01 -0.0203 658 1 0 0.98 0.483 3.87 -0.0914 571 1 0 0.913 0.479 1.19 PRS_PLINK_5e.04 279.7 Other immunological findings Both 12 42 3 endocrine/metabolic brown 42, 12 11, 3 10, 2 10, 4 11, 3 -0.084 0.382 0.826 0.083 0.919 0.426 1.85 -0.277 1.36 0.839 0.076 0.758 0.0436 15.1 0.289 1.04 0.78 0.108 1.34 0.221 9.17 0.0444 1.09 0.968 0.014 1.05 0.133 7.57 PRS_PLINK_5e.04 279.8 Other specified disorders involving the immune mechanism Both 3 9 3 endocrine/metabolic brown 9, 3 3, 1 2, 1 2, 0 2, 1 0.093 1.6 0.954 0.021 1.1 0.0651 100 0.0353 167 1 0 1.04 0.545 1.22 -0.0394 2230 1 0 0.961 0.791 1.46 -0.0229 664 1 0 0.977 0.51 1.22 PRS_PLINK_5e.04 280 Iron deficiency anemias Both 11 40 4 hematopoietic darkorange1 40, 11 10, 4 10, 2 10, 0 10, 5 0.211 0.394 0.592 0.228 1.23 0.599 2.66 -1.05 1.49 0.482 0.317 0.351 0.00226 6.16 -2.13 1.6 0.183 0.737 0.119 0.00018 1.98 0.192 1.11 0.863 0.064 1.21 0.168 13.2 PRS_PLINK_5e.04 280.1 Iron deficiency anemias, unspecified or not due to blood loss Both 11 39 4 hematopoietic darkorange1 39, 11 10, 4 10, 2 9, 1 10, 4 0.21 0.393 0.593 0.227 1.23 0.6 2.65 -0.85 1.35 0.528 0.277 0.427 0.00403 6.57 -1.05 1.5 0.483 0.316 0.349 0.0031 6.16 0.117 1.11 0.916 0.038 1.12 0.155 13.3 PRS_PLINK_5e.04 280.2 Iron deficiency anemia secondary to blood loss (chronic) Both 3 16 4 hematopoietic darkorange1 16, 3 4, 1 4, 0 4, 1 4, 1 0.524 1.03 0.61 0.215 1.69 0.246 50.1 -0.794 689 0.999 0 0.452 0.117 3.42 -1.16 31.3 0.971 0.013 0.314 0.301 82.6 -2 4.66 0.667 0.176 0.135 0.000124 117 PRS_PLINK_5e.04 281 Other deficiency anemia Both 1 6 4 hematopoietic darkorange1 6, 1 2, 0 1, 0 1, 0 2, 1 1.1 87 0.99 0.004 3 0.000226 40000 1.62 1490 0.999 0 5.07 0.131 88.2 PRS_PLINK_5e.04 281.1 Megaloblastic anemia Both 0 4 4 hematopoietic darkorange1 4, 0 1 1 1 1 PRS_PLINK_5e.04 281.11 Pernicious anemia Both 0 3 4 hematopoietic darkorange1 3, 0 1 1 1 1 PRS_PLINK_5e.04 281.12 Other vitamin B12 deficiency anemia Both 0 3 4 hematopoietic darkorange1 3, 0 1 1 1 1 PRS_PLINK_5e.04 281.9 Deficiency anemias Both 1 1 4 hematopoietic darkorange1 1, 1 -0.0277 150 1 0 0.973 0.133 8.43 PRS_PLINK_5e.04 282 Hereditary hemolytic anemias Both 1 5 4 hematopoietic darkorange1 5, 1 2, 0 1, 1 1, 0 1, 0 -0.571 1360 1 0 0.565 0.179 4.41 -0.0307 2150 1 0 0.97 0.315 2.85 PRS_PLINK_5e.04 282.8 Other hemoglobinopathies Both 1 3 4 hematopoietic darkorange1 3, 1 1, 1 1, 0 1, 0 1, 1 0.505 105000 1 0 1.66 2.06e-15 13400000 0.0136 32.9 1 0 1.01 0.863 2.65 -0.00813 28.3 1 0 0.992 0.224 14.2 PRS_PLINK_5e.04 282.9 Other hereditary hemolytic anemias Both 1 2 4 hematopoietic darkorange1 2, 1 1, 0 1, 1 1, 0 1, 1 -0.0183 739 1 0 0.982 0.666 1.64 0.000289 62.5 1 0 1 0.961 1.03 PRS_PLINK_5e.04 284 Aplastic anemia Both 1 7 4 hematopoietic darkorange1 7, 1 2, 0 2, 0 1, 0 2, 1 -0.169 262 0.999 0 0.844 0.797 1.11 -0.622 5700 1 0 0.537 0.488 2.3 PRS_PLINK_5e.04 284.1 Pancytopenia Both 1 6 4 hematopoietic darkorange1 6, 1 2, 0 1, 0 1, 0 2, 1 -0.187 473 1 0 0.829 0.748 2.65 -1.66 24600 1 0 0.19 0.0313 38.3 PRS_PLINK_5e.04 285 Other anemias Both 13 43 4 hematopoietic darkorange1 43, 13 11, 7 11, 0 10, 1 11, 5 0.0528 0.418 0.9 0.046 1.05 0.473 2.3 -5.87 2.89 0.0427 1.37 0.00284 2.58e-09 0.31 -3.97 2.12 0.0618 1.209 0.0189 1.07e-06 0.834 -1.59 1.12 0.154 0.813 0.203 0.017 1.34 PRS_PLINK_5e.04 285.1 Acute posthemorrhagic anemia Both 0 29 4 hematopoietic darkorange1 29, 0 8 7 7 7 PRS_PLINK_5e.04 285.2 Anemia of chronic disease Both 1 23 4 hematopoietic darkorange1 23, 1 6, 0 6, 0 5, 0 6, 1 0.568 1.06 0.592 0.227 1.76 0.0808 121 2.15 3.43 0.531 0.275 8.61 0.0626 10.4 PRS_PLINK_5e.04 285.21 Anemia in chronic kidney disease Both 0 16 4 hematopoietic darkorange1 16, 0 4 4 4 4 PRS_PLINK_5e.04 285.22 Anemia in neoplastic disease Both 0 5 4 hematopoietic darkorange1 5, 0 2 1 1 1 PRS_PLINK_5e.04 286 Coagulation defects Both 7 40 4 hematopoietic darkorange1 40, 7 10, 5 10, 1 10, 0 10, 1 -0.482 0.487 0.323 0.491 0.618 0.17 1.48 -2.09 1.98 0.291 0.537 0.123 5.99e-06 4.86 -1.45 1.59 0.363 0.441 0.235 7.9e-07 5.74 -1.28 1.89 0.498 0.302 0.278 3.02e-06 6.83 PRS_PLINK_5e.04 286.1 Congenital coagulation defects Both 0 8 4 hematopoietic darkorange1 8, 0 2 2 2 2 PRS_PLINK_5e.04 286.11 Von willebrand's disease Both 0 3 4 hematopoietic darkorange1 3, 0 1 1 1 1 PRS_PLINK_5e.04 286.12 Congenital deficiency of other clotting factors (including factor VII) Both 0 4 4 hematopoietic darkorange1 4, 0 1 1 1 1 PRS_PLINK_5e.04 286.2 Encounter for long-term (current) use of anticoagulants Both 3 32 4 hematopoietic darkorange1 32, 3 8, 1 8, 0 8, 1 8, 1 0.319 0.69 0.643 0.191 1.38 0.22 7.58 0.74 2.01 0.713 0.147 2.1 0.0342 1280 0.508 1.4 0.717 0.145 1.66 0.153 812 0.526 1.69 0.756 0.121 1.69 6.93e-05 281 PRS_PLINK_5e.04 286.3 Coagulation defects complicating pregnancy or postpartum Female 1 2 4 hematopoietic darkorange1 2, 1 1, 0 1, 1 1, 0 1, 1 0.213 5420 1 0 1.24 0.222 1.55 0.517 5330 1 0 1.68 0.358 2.33 PRS_PLINK_5e.04 286.4 Acquired coagulation factor deficiency Both 0 3 4 hematopoietic darkorange1 3, 0 1 1 1 1 PRS_PLINK_5e.04 286.5 Hemorrhagic disorder due to intrinsic circulating anticoagulants Both 0 4 4 hematopoietic darkorange1 4, 0 1 1 1 1 PRS_PLINK_5e.04 286.6 Defibrination syndrome Both 5 37 4 hematopoietic darkorange1 37, 5 10, 4 9, 1 9, 0 9, 0 -0.56 0.575 0.331 0.481 0.571 0.0561 1.54 -1.39 1.71 0.418 0.379 0.249 0.00022 5.33 -1.23 1.58 0.436 0.36 0.292 0.00037 5.98 -1.08 1.67 0.516 0.288 0.338 5.11e-05 8.66 PRS_PLINK_5e.04 286.7 Other and unspecified coagulation defects Both 6 40 4 hematopoietic darkorange1 40, 6 10, 4 10, 1 10, 0 10, 1 -0.408 0.506 0.42 0.377 0.665 0.185 1.64 -0.907 1.56 0.561 0.251 0.404 2.21e-05 7.46 -1.14 1.69 0.499 0.302 0.32 0.00024 13.8 -2.9 2.72 0.287 0.543 0.0552 2.03e-06 5.98 PRS_PLINK_5e.04 286.8 Hypercoagulable state Both 1 13 4 hematopoietic darkorange1 13, 1 4, 1 3, 0 3, 0 3, 0 0.0807 1.12 0.943 0.026 1.08 0.0863 10.7 0.122 290 1 0 1.13 0.303 4.6 0.317 410 0.999 0 1.37 0.0986 30.6 -3.93 1240 0.997 0.001 0.0196 1.71e-07 1270 PRS_PLINK_5e.04 286.81 Primary hypercoagulable state Both 1 11 4 hematopoietic darkorange1 11, 1 3, 1 3, 0 2, 0 3, 0 -0.0898 1.51 0.953 0.021 0.914 0.0617 11.4 0.00935 363 1 0 1.01 0.728 1.92 -1.02 96300000 1 0 0.36 8.78e-09 53800000 -0.00208 199 1 0 0.998 4.27e-07 2260000 PRS_PLINK_5e.04 286.9 Abnormal coagulation profile Both 2 14 4 hematopoietic darkorange1 14, 2 4, 2 3, 0 3, 0 4, 0 0.265 1.55 0.864 0.063 1.3 0.00482 1470 0.108 3500 1 0 1.11 0.593 4.03 -0.0396 1130 1 0 0.961 0.462 1.18 -1.14 88.3 0.99 0.004 0.32 0.298 0.344 PRS_PLINK_5e.04 287 Purpura and other hemorrhagic conditions Both 3 36 4 hematopoietic darkorange1 36, 3 8, 1 9, 1 9, 0 9, 1 0.797 0.747 0.286 0.544 2.22 0.505 982 1.01 1.64 0.539 0.268 2.73 0.091 2400 -0.419 1.76 0.811 0.091 0.657 0.00149 69.3 -0.0328 1.76 0.985 0.007 0.968 0.000156 278 PRS_PLINK_5e.04 287.1 Spontaneous ecchymoses Both 0 3 4 hematopoietic darkorange1 3, 0 1 1 1 1 PRS_PLINK_5e.04 287.3 Thrombocytopenia Both 3 33 4 hematopoietic darkorange1 33, 3 8, 1 8, 1 8, 0 8, 1 0.534 0.685 0.435 0.361 1.71 0.404 40.6 0.925 1.68 0.582 0.235 2.52 0.0803 3150 -0.0748 1.87 0.968 0.014 0.928 0.00105 206 -0.122 1.73 0.944 0.025 0.885 8.88e-05 143 PRS_PLINK_5e.04 287.31 Primary thrombocytopenia Both 1 5 4 hematopoietic darkorange1 5, 1 2, 1 1, 0 1, 0 1, 0 0.0147 356 1 0 1.01 0.85 1.22 1.25 18200 1 0 3.49 0.236 4.25 1.01 4770 1 0 2.74 0.289 3.03 -0.0167 281 1 0 0.983 0.841 1.12 PRS_PLINK_5e.04 287.32 Secondary thrombocytopenia Both 1 10 4 hematopoietic darkorange1 10, 1 3, 1 2, 0 2, 0 3, 0 -3.46 10.5 0.741 0.13 0.0316 0.0251 0.0394 3.09 1.37e+08 1 0 22 1.07e-13 5.24e+16 -0.0851 1250 1 0 0.918 0.0577 5.93 -0.303 12600000 1 0 0.739 0.144 1.78 PRS_PLINK_5e.04 287.4 Qualitative platelet defects Both 0 2 4 hematopoietic darkorange1 2, 0 1 1 1 1 PRS_PLINK_5e.04 288 Diseases of white blood cells Both 7 51 4 hematopoietic darkorange1 51, 7 12, 1 13, 3 12, 2 13, 1 -0.182 0.442 0.681 0.167 0.834 0.319 1.91 0.468 1.27 0.713 0.147 1.6 0.125 34.6 0.0385 1.39 0.978 0.01 1.04 0.00197 34.1 -0.4 1.34 0.764 0.117 0.67 0.00275 8.46 PRS_PLINK_5e.04 288.1 Decreased white blood cell count Both 2 19 4 hematopoietic darkorange1 19, 2 5, 0 5, 1 4, 0 5, 1 0.345 0.954 0.718 0.144 1.41 0.00841 67.2 -0.239 2.78 0.931 0.031 0.787 0.0117 158 -0.0016 16.2 1 0 0.998 0.00163 590 PRS_PLINK_5e.04 288.11 Neutropenia Both 2 17 4 hematopoietic darkorange1 17, 2 5, 0 4, 0 4, 1 4, 1 0.0665 0.948 0.944 0.025 1.07 0.0459 22.9 -4.54e-14 14.4 1 0 1 2.24e-05 45600 -0.442 11.1 0.968 0.014 0.643 0.00457 73 PRS_PLINK_5e.04 288.2 Elevated white blood cell count Both 5 47 4 hematopoietic darkorange1 47, 5 12, 1 12, 1 11, 2 12, 1 -0.123 0.539 0.819 0.087 0.884 0.237 2.49 -1.17 1.55 0.452 0.345 0.311 0.00215 7.04 -0.909 1.55 0.557 0.254 0.403 0.00272 7.53 -0.371 1.35 0.784 0.106 0.69 0.00273 8.78 PRS_PLINK_5e.04 288.3 Eosinophilia Both 2 0 4 hematopoietic darkorange1 0, 2 PRS_PLINK_5e.04 289 Other diseases of blood and blood-forming organs Both 2 26 4 hematopoietic darkorange1 26, 2 7, 2 6, 0 6, 0 7, 0 -0.517 0.701 0.462 0.336 0.597 0.00377 2.56 -0.231 2.29 0.919 0.036 0.793 0.00487 157 0.246 1.93 0.898 0.047 1.28 0.0118 83.5 -1.26 2.28 0.581 0.236 0.285 0.00171 42.8 PRS_PLINK_5e.04 289.3 Personal history of diseases of blood and blood-forming organs Both 1 15 4 hematopoietic darkorange1 15, 1 4, 1 4, 0 3, 0 4, 0 -0.507 0.934 0.587 0.231 0.602 0.0367 2.83 0.633 30.9 0.984 0.007 1.88 0.321 26.9 -0.556 28100000 1 0 0.574 0.00347 28.7 -0.494 3700000 1 0 0.61 2.4e-05 727 PRS_PLINK_5e.04 289.4 Lymphadenitis Both 5 45 4 hematopoietic darkorange1 45, 5 12, 1 11, 1 11, 1 11, 2 0.216 0.432 0.617 0.21 1.24 0.496 3.26 -0.115 1.52 0.94 0.027 0.891 0.0158 88.8 -0.147 1.34 0.912 0.04 0.863 0.000213 17.6 0.645 1.27 0.61 0.215 1.91 0.121 96.3 PRS_PLINK_5e.04 289.5 Diseases of spleen Both 0 5 4 hematopoietic darkorange1 5, 0 2 1 1 1 PRS_PLINK_5e.04 289.8 Polycythemia, secondary Both 1 9 4 hematopoietic darkorange1 9, 1 3, 0 2, 0 2, 1 2, 0 0.0345 34.1 0.999 0 1.04 0.0582 15.3 -0.174 9590 1 0 0.84 0.106 2.32 PRS_PLINK_5e.04 289.9 Abnormality of red blood cells Both 0 8 4 hematopoietic darkorange1 8, 0 2 2 2 2 PRS_PLINK_5e.04 290 Delirium dementia and amnestic and other cognitive disorders Both 1 9 5 mental disorders magenta 9, 1 3, 1 2, 0 2, 0 2, 0 -0.467 2.82 0.869 0.061 0.627 0.00697 48.3 0.0539 4490 1 0 1.06 0.606 6.67 0.419 453 0.999 0 1.52 0.689 1.59 -0.394 1400 1 0 0.674 0.553 2.07 PRS_PLINK_5e.04 290.1 Dementias Both 1 2 5 mental disorders magenta 2, 1 1, 1 1, 0 1, 1 1, 0 0.0431 1390 1 0 1.04 0.794 1.82 0.0941 1700 1 0 1.1 0.764 2.39 PRS_PLINK_5e.04 290.11 Alzheimer's disease Both 0 1 5 mental disorders magenta 1, 0 PRS_PLINK_5e.04 290.13 Senile dementia Both 1 3 5 mental disorders magenta 3, 1 1, 1 1, 0 1, 0 1, 1 0.208 729 1 0 1.23 0.716 2.5 0.0941 1700 1 0 1.1 0.764 2.39 -0.00282 32.5 1 0 0.997 0.947 1.02 PRS_PLINK_5e.04 290.2 Delirium due to conditions classified elsewhere Both 0 5 5 mental disorders magenta 5, 0 2 1 1 1 PRS_PLINK_5e.04 290.3 Other persistent mental disorders due to conditions classified elsewhere Both 0 10 5 mental disorders magenta 10, 0 3 2 2 3 PRS_PLINK_5e.04 291 Other specified nonpsychotic and/or transient mental disorders Both 2 36 5 mental disorders magenta 36, 2 9, 1 9, 1 9, 0 9, 0 -0.669 0.694 0.335 0.475 0.512 0.0156 2.15 -0.685 1.91 0.72 0.143 0.504 0.00829 87.6 -0.545 1.62 0.737 0.133 0.58 0.0171 10.8 -0.623 2.02 0.758 0.121 0.536 0.00576 95.3 PRS_PLINK_5e.04 291.1 Transient mental disorders due to conditions classified elsewhere Both 0 4 5 mental disorders magenta 4, 0 1 1 1 1 PRS_PLINK_5e.04 291.4 Specific nonpsychotic mental disorders due to brain damage Both 0 9 5 mental disorders magenta 9, 0 3 2 2 2 PRS_PLINK_5e.04 291.8 Alteration of consciousness Both 2 27 5 mental disorders magenta 27, 2 7, 0 7, 1 6, 1 7, 0 -0.415 0.66 0.529 0.277 0.66 0.000602 3.95 1.41 2.23 0.527 0.278 4.1 0.0471 2050 0.0427 2.09 0.984 0.007 1.04 0.00976 95.7 PRS_PLINK_5e.04 292 Neurological disorders Both 8 51 5 mental disorders magenta 51, 8 12, 4 13, 3 12, 0 13, 1 -0.774 0.528 0.143 0.845 0.461 0.116 1.24 -0.316 0.915 0.73 0.137 0.729 0.124 3.73 -1.24 1.24 0.32 0.495 0.291 0.000676 2.71 -1.81 1.46 0.215 0.667 0.164 0.000191 2.02 PRS_PLINK_5e.04 292.1 Aphasia/speech disturbance Both 3 20 5 mental disorders magenta 20, 3 5, 2 5, 0 5, 0 5, 1 0.637 1.08 0.557 0.254 1.89 0.167 39.1 4.92 9.24 0.594 0.226 137 9.87e-05 9.03e+09 -1.14 4.27 0.789 0.103 0.319 6e-05 207000 0.758 2.49 0.761 0.119 2.13 6.94e-05 23600 PRS_PLINK_5e.04 292.11 Aphasia Both 2 0 5 mental disorders magenta 0, 2 PRS_PLINK_5e.04 292.12 Symbolic dysfunction Both 1 4 5 mental disorders magenta 4, 1 1, 0 1, 0 1, 0 1, 1 -0.28 18600 1 0 0.756 1.18e-05 756000 -0.017 35.2 1 0 0.983 0.768 1.11 PRS_PLINK_5e.04 292.2 Mild cognitive impairment Both 1 3 5 mental disorders magenta 3, 1 1, 0 1, 1 1, 0 1, 1 0.0977 1320 1 0 1.1 0.796 2.3 PRS_PLINK_5e.04 292.3 Memory loss Both 2 24 5 mental disorders magenta 24, 2 6, 1 6, 0 6, 0 6, 1 0.0218 0.785 0.978 0.01 1.02 0.0838 7.03 -2.27 5.5 0.68 0.168 0.103 2.03e-05 380 -3.48 5.34 0.515 0.288 0.0309 1.24e-06 87.9 -0.495 3.38 0.884 0.054 0.61 0.000124 724 PRS_PLINK_5e.04 292.4 Altered mental status Both 3 28 5 mental disorders magenta 28, 3 7, 2 7, 0 7, 0 7, 1 -0.546 0.764 0.475 0.323 0.579 0.018 2.26 -2.78 2.54 0.275 0.561 0.0621 9.21e-06 2.92 -0.858 1.94 0.658 0.182 0.424 0.00339 11.4 -0.596 1.67 0.721 0.142 0.551 0.00515 7.95 PRS_PLINK_5e.04 292.5 Transient alteration of awareness Both 0 7 5 mental disorders magenta 7, 0 2 2 1 2 PRS_PLINK_5e.04 292.6 Hallucinations Both 0 2 5 mental disorders magenta 2, 0 1 1 1 1 PRS_PLINK_5e.04 293 Symptoms involving head and neck Both 2 9 5 mental disorders magenta 9, 2 3, 0 2, 0 2, 2 2, 0 1.28 6.33 0.839 0.076 3.6 3.35 3.94 0.0581 213 1 0 1.06 0.477 1.45 PRS_PLINK_5e.04 293.1 Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS] Both 4 47 5 mental disorders magenta 47, 4 12, 0 12, 3 11, 0 12, 1 -0.0654 0.749 0.93 0.031 0.937 0.0231 9.8 1.4 1.42 0.322 0.492 4.07 0.205 782 0.436 1.36 0.748 0.126 1.55 0.0921 108 PRS_PLINK_5e.04 295 Schizophrenia and other psychotic disorders Both 0 7 5 mental disorders magenta 7, 0 2 2 1 2 PRS_PLINK_5e.04 295.1 Schizophrenia Both 0 1 5 mental disorders magenta 1, 0 PRS_PLINK_5e.04 295.2 Paranoid disorders Both 0 3 5 mental disorders magenta 3, 0 1 1 1 1 PRS_PLINK_5e.04 295.3 Psychosis Both 0 7 5 mental disorders magenta 7, 0 2 2 1 2 PRS_PLINK_5e.04 296 Mood disorders Both 29 19 5 mental disorders magenta 19, 29 5, 6 5, 10 4, 3 5, 9 0.0766 0.334 0.819 0.087 1.08 0.582 2 -0.112 1.16 0.923 0.035 0.894 0.103 7.04 0.352 1.26 0.779 0.108 1.42 0.216 13.2 0.42 1.15 0.715 0.146 1.52 0.214 15.8 PRS_PLINK_5e.04 296.1 Bipolar Both 2 13 5 mental disorders magenta 13, 2 4, 0 3, 0 3, 0 3, 2 0.528 0.892 0.554 0.257 1.7 0.108 7.72 -0.031 292000 1 0 0.969 0.577 1.99 PRS_PLINK_5e.04 296.2 Depression Both 28 19 5 mental disorders magenta 19, 28 5, 6 5, 9 4, 3 5, 9 0.0853 0.335 0.799 0.097 1.09 0.588 2.01 -0.491 1.25 0.695 0.158 0.612 0.0489 6.08 0.352 1.26 0.779 0.108 1.42 0.216 13.2 0.42 1.15 0.715 0.146 1.52 0.214 15.8 PRS_PLINK_5e.04 296.22 Major depressive disorder Both 28 19 5 mental disorders magenta 19, 28 5, 6 5, 9 4, 3 5, 9 0.0853 0.335 0.799 0.097 1.09 0.588 2.01 -0.491 1.25 0.695 0.158 0.612 0.0489 6.08 0.352 1.26 0.779 0.108 1.42 0.216 13.2 0.42 1.15 0.715 0.146 1.52 0.214 15.8 PRS_PLINK_5e.04 297 Suicidal ideation or attempt Both 1 14 5 mental disorders magenta 14, 1 4, 1 3, 0 3, 0 4, 0 -0.784 1.29 0.544 0.265 0.456 0.0244 3.71 -1.3 15500000 1 0 0.274 0.000215 101 -0.013 71.9 1 0 0.987 0.726 1.55 -1.17 979 0.999 0 0.309 0.147 0.151 PRS_PLINK_5e.04 297.1 Suicidal ideation Both 1 10 5 mental disorders magenta 10, 1 3, 1 2, 0 2, 0 3, 0 -0.269 1.8 0.881 0.055 0.764 0.747 0.792 0.0764 18800 1 0 1.08 0.289 4.51 -0.0169 1480 1 0 0.983 0.82 1.16 -0.098 1300 1 0 0.907 0.428 1.31 PRS_PLINK_5e.04 297.2 Suicide or self-inflicted injury Both 0 7 5 mental disorders magenta 7, 0 2 2 1 2 PRS_PLINK_5e.04 300 Anxiety disorders Both 25 19 5 mental disorders magenta 19, 25 5, 6 5, 8 4, 2 5, 8 -0.163 0.394 0.679 0.168 0.85 0.38 1.72 -0.517 1.11 0.641 0.193 0.596 0.062 4.04 1.73 2.34 0.46 0.337 5.63 0.206 6.69 -0.382 1.18 0.746 0.127 0.683 0.0132 7.83 PRS_PLINK_5e.04 300.1 Anxiety disorder Both 24 19 5 mental disorders magenta 19, 24 5, 6 5, 8 4, 2 5, 7 -0.201 0.405 0.62 0.208 0.818 0.356 1.68 -0.517 1.11 0.641 0.193 0.596 0.062 4.04 1.73 2.34 0.46 0.337 5.63 0.206 6.69 -0.518 1.2 0.665 0.177 0.596 0.000111 6.67 PRS_PLINK_5e.04 300.11 Generalized anxiety disorder Both 12 18 5 mental disorders magenta 18, 12 5, 3 4, 3 4, 3 5, 3 -0.0152 0.584 0.979 0.009 0.985 0.337 2.9 1.15 1.99 0.565 0.248 3.15 0.173 8.91e+08 1.71 1.78 0.336 0.474 5.55 0.527 243 -0.113 1.86 0.952 0.021 0.893 0.0206 485 PRS_PLINK_5e.04 300.12 Agorophobia, social phobia, and panic disorder Both 2 15 5 mental disorders magenta 15, 2 4, 1 4, 1 3, 0 4, 0 -0.795 1.16 0.492 0.308 0.451 0.0144 15.2 2.1 3.78 0.579 0.237 8.15 0.0695 9.48 -0.0634 62.2 0.999 0 0.939 0.792 1.12 0.644 3.24 0.842 0.074 1.9 1.72 2.05 PRS_PLINK_5e.04 300.13 Phobia Both 3 12 5 mental disorders magenta 12, 3 3, 2 3, 1 3, 0 3, 0 -0.612 1.03 0.55 0.259 0.542 0.0312 3.61 0.47 4.52 0.917 0.038 1.6 1.52 1.66 -0.00479 51.4 1 0 0.995 0.803 1.33 -0.869 619 0.999 0 0.419 0.732 0.778 PRS_PLINK_5e.04 300.3 Obsessive-compulsive disorders Both 0 6 5 mental disorders magenta 6, 0 2 1 1 2 PRS_PLINK_5e.04 300.4 Dysthymic disorder Both 8 17 5 mental disorders magenta 17, 8 5, 2 4, 2 4, 1 4, 3 -0.308 0.821 0.707 0.15 0.735 0.083 2.99 0.128 1.69 0.939 0.027 1.14 3.09e-08 15.5 0.115 4.01 0.977 0.01 1.12 0.00286 2830 0.0614 1.86 0.974 0.012 1.06 0.0407 82.6 PRS_PLINK_5e.04 300.8 Acute reaction to stress Both 0 2 5 mental disorders magenta 2, 0 1 1 1 1 PRS_PLINK_5e.04 300.9 Posttraumatic stress disorder Both 1 7 5 mental disorders magenta 7, 1 2, 1 2, 0 1, 0 2, 0 1.14 555 0.998 0.001 3.13 25 73.8 0.403 2.6e+07 1 0 1.5 3.79e-13 1.34e+13 0.00946 35.6 1 0 1.01 0.946 1.12 0.0613 47 0.999 0 1.06 0.826 4.24 PRS_PLINK_5e.04 301 Personality disorders Both 0 6 5 mental disorders magenta 6, 0 2 1 1 2 PRS_PLINK_5e.04 301.2 Antisocial/borderline personality disorder Both 0 3 5 mental disorders magenta 3, 0 1 1 1 1 PRS_PLINK_5e.04 302 Sexual and gender identity disorders Both 9 13 5 mental disorders magenta 13, 9 4, 3 3, 4 3, 0 3, 2 -0.976 0.873 0.264 0.579 0.377 0.000519 1.59 0.2 1.36 0.884 0.054 1.22 0.0339 18.3 1.22 44.2 0.978 0.01 3.4 8.12 15.4 -0.794 2.06 0.699 0.155 0.452 0.418 0.551 PRS_PLINK_5e.04 302.1 Decreased libido Both 1 4 5 mental disorders magenta 4, 1 1, 0 1, 0 1, 0 1, 1 0.141 708 1 0 1.15 0.421 4.31 -0.00668 47.3 1 0 0.993 0.927 1.04 PRS_PLINK_5e.04 303 Psychogenic and somatoform disorders Both 8 16 5 mental disorders magenta 16, 8 4, 1 4, 3 4, 1 4, 3 -0.0703 1.01 0.945 0.025 0.932 0.0167 6.58 0.272 4.81 0.955 0.02 1.31 1.03 1.44 -0.235 48.7 0.996 0.002 0.79 1.61e-06 0.938 -0.282 2.06 0.891 0.05 0.754 0.00628 22.2 PRS_PLINK_5e.04 303.1 Dissociative disorder Both 0 5 5 mental disorders magenta 5, 0 2 1 1 1 PRS_PLINK_5e.04 303.3 Psychogenic disorder Both 8 16 5 mental disorders magenta 16, 8 4, 1 4, 3 4, 1 4, 3 -0.0703 1.01 0.945 0.025 0.932 0.0167 6.58 0.272 4.81 0.955 0.02 1.31 1.03 1.44 -0.235 48.7 0.996 0.002 0.79 1.61e-06 0.938 -0.282 2.06 0.891 0.05 0.754 0.00628 22.2 PRS_PLINK_5e.04 303.31 Gastrointestinal malfunction arising from mental factors Both 1 5 5 mental disorders magenta 5, 1 2, 0 1, 0 1, 1 1, 0 0.00346 249 1 0 1 0.835 1.42 7.28 19900 1 0 1450 3.77e-12 1.32e+18 PRS_PLINK_5e.04 303.4 Somatoform disorder Both 0 13 5 mental disorders magenta 13, 0 4 3 3 3 PRS_PLINK_5e.04 304 Adjustment reaction Both 10 18 5 mental disorders magenta 18, 10 5, 1 4, 2 4, 3 5, 4 0.429 0.652 0.511 0.292 1.54 0.472 5.13 0.482 1.64 0.768 0.115 1.62 0.0864 30.9 1.4 1.69 0.408 0.389 4.07 0.352 64.9 0.338 1.93 0.861 0.065 1.4 0.0527 96.3 PRS_PLINK_5e.04 305.2 Eating disorder Both 1 10 5 mental disorders magenta 10, 1 3, 1 2, 0 2, 0 3, 0 -0.878 4.54 0.847 0.072 0.416 0.0232 6.68 0.0228 4290 1 0 1.02 0.092 54.6 0.0764 18800 1 0 1.08 0.289 4.51 -0.00634 731 1 0 0.994 0.778 1.13 PRS_PLINK_5e.04 306 Other mental disorder Both 6 14 5 mental disorders magenta 14, 6 4, 3 3, 2 3, 0 4, 1 0.106 1.08 0.922 0.035 1.11 0.0649 57 1.88 13.7 0.892 0.05 6.52 4.82 8.98 -2.64 350 0.994 0.003 0.0717 0.0045 0.0119 -0.303 2.11 0.886 0.053 0.738 0.0105 17.5 PRS_PLINK_5e.04 306.1 Mental disorders durring/after pregnancy Female 1 6 5 mental disorders magenta 6, 1 2, 1 1, 0 1, 0 2, 0 -0.00369 4480 1 0 0.996 0.0455 15.4 -0.291 3240 1 0 0.748 0.715 2.3 -0.0615 6070 1 0 0.94 0.136 6.2 -0.333 6250 1 0 0.717 0.0574 8.54 PRS_PLINK_5e.04 306.9 Tension headache Both 4 10 5 mental disorders magenta 10, 4 3, 2 2, 1 2, 0 3, 1 0.107 0.948 0.911 0.041 1.11 0.0747 21 -0.521 634 0.999 0 0.594 0.0597 0.1 0.0441 551 1 0 1.05 0.815 1.13 -0.0767 98.2 0.999 0 0.926 1.23 1.49 PRS_PLINK_5e.04 312 Conduct disorders Both 2 1 5 mental disorders magenta 1, 2 -0.000716 355 1 0 0.999 0.991 1.18 PRS_PLINK_5e.04 312.3 Impulse control disorder Both 1 0 5 mental disorders magenta 0, 1 PRS_PLINK_5e.04 313 Pervasive developmental disorders Both 3 28 5 mental disorders magenta 28, 3 7, 0 7, 1 7, 0 7, 1 0.126 0.621 0.839 0.076 1.13 0.186 3.73 -0.276 2.24 0.902 0.045 0.759 0.000214 1630 0.323 4.7 0.945 0.024 1.38 1.29e-06 27600 PRS_PLINK_5e.04 313.1 Attention deficit hyperactivity disorder Both 3 25 5 mental disorders magenta 25, 3 7, 0 6, 1 6, 0 6, 1 0.0365 0.624 0.953 0.021 1.04 0.0751 3.26 -0.0328 1.94 0.986 0.006 0.968 0.00827 72.5 0.0506 4.79 0.992 0.004 1.05 2.81e-05 14400 PRS_PLINK_5e.04 313.2 Tics and stuttering Both 0 1 5 mental disorders magenta 1, 0 PRS_PLINK_5e.04 313.3 Autism Both 0 2 5 mental disorders magenta 2, 0 1 1 1 1 PRS_PLINK_5e.04 315 Develomental delays and disorders Both 2 13 5 mental disorders magenta 13, 2 4, 1 3, 1 3, 0 3, 0 -0.303 2.31 0.895 0.048 0.738 0.0121 28.2 -0.0691 80 0.999 0 0.933 0.709 1.16 -0.0856 202 1 0 0.918 0.536 1.38 -0.262 66 0.997 0.001 0.769 0.418 0.752 PRS_PLINK_5e.04 315.1 Learning disorder Both 0 2 5 mental disorders magenta 2, 0 1 1 1 1 PRS_PLINK_5e.04 315.2 Speech and language disorder Both 2 5 5 mental disorders magenta 5, 2 2, 2 1, 0 1, 0 1, 0 0.343 79 0.997 0.002 1.41 0.14 21.9 -0.36 3550 1 0 0.698 0.654 3.46 -0.459 6900 1 0 0.632 0.604 2.9 0.199 2590 1 0 1.22 0.757 1.41 PRS_PLINK_5e.04 316 Substance addiction and disorders Both 3 49 5 mental disorders magenta 49, 3 12, 1 12, 0 12, 0 12, 2 0.0822 0.521 0.875 0.058 1.09 0.196 3.48 -1.05 1.36 0.441 0.356 0.35 0.000565 4.57 -0.433 1.34 0.746 0.127 0.648 0.00704 11.4 -0.412 1.5 0.783 0.106 0.662 3.15e-06 8.72 PRS_PLINK_5e.04 316.1 Polyneuropathy due to drugs Both 0 4 5 mental disorders magenta 4, 0 1 1 1 1 PRS_PLINK_5e.04 317 Alcohol-related disorders Both 0 36 5 mental disorders magenta 36, 0 8 9 9 9 PRS_PLINK_5e.04 317.1 Alcoholism Both 0 29 5 mental disorders magenta 29, 0 8 7 7 7 PRS_PLINK_5e.04 317.11 Alcoholic liver damage Both 0 7 5 mental disorders magenta 7, 0 2 2 1 2 PRS_PLINK_5e.04 318 Tobacco use disorder Both 9 51 5 mental disorders magenta 51, 9 12, 2 13, 3 12, 1 13, 3 -0.227 0.452 0.615 0.211 0.797 0.285 1.88 -0.0587 1.16 0.96 0.018 0.943 0.0934 10.7 -0.695 1.3 0.593 0.227 0.499 0.00655 6.22 -0.169 1.1 0.878 0.057 0.845 0.0649 6.88 PRS_PLINK_5e.04 320 Meningitis Both 1 3 6 neurological darkblue 3, 1 1, 0 1, 0 1, 1 1, 0 0.0389 1120 1 0 1.04 0.884 1.45 0.0289 2500 1 0 1.03 0.837 1.08 PRS_PLINK_5e.04 323 Encephalitis Both 1 1 6 neurological darkblue 1, 1 -0.0777 84.5 0.999 0 0.925 0.75 1.21 PRS_PLINK_5e.04 323.8 Encephalitis, non-infectious Both 1 1 6 neurological darkblue 1, 1 -0.0777 84.5 0.999 0 0.925 0.75 1.21 PRS_PLINK_5e.04 324 Other CNS infection and poliomyelitis Both 0 5 6 neurological darkblue 5, 0 2 1 1 1 PRS_PLINK_5e.04 327 Sleep disorders Both 24 38 6 neurological darkblue 38, 24 9, 5 9, 5 9, 9 10, 5 0.0156 0.307 0.96 0.018 1.02 0.567 1.79 0.127 1.01 0.899 0.046 1.14 0.195 7.03 0.388 0.887 0.662 0.179 1.47 0.3 7.38 -0.595 0.997 0.551 0.259 0.552 0.065 3.01 PRS_PLINK_5e.04 327.1 Hypersomnia Both 5 21 6 neurological darkblue 21, 5 6, 0 5, 3 5, 1 5, 1 -0.616 0.962 0.522 0.282 0.54 0.0538 3.36 1.5 1.65 0.362 0.441 4.5 0.154 24100 0.323 3.93 0.934 0.029 1.38 1.12e-05 7770 0.0637 2.08 0.976 0.011 1.07 0.002 35.1 PRS_PLINK_5e.04 327.3 Sleep apnea Both 21 37 6 neurological darkblue 37, 21 9, 4 9, 3 9, 8 9, 6 0.0652 0.319 0.838 0.077 1.07 0.587 1.93 -0.444 1.15 0.7 0.155 0.642 0.0805 4.37 0.664 0.982 0.499 0.302 1.94 0.36 13.1 -0.393 1.06 0.71 0.149 0.675 0.061 4.19 PRS_PLINK_5e.04 327.31 Central/nonobstroctive sleep apnea Both 2 5 6 neurological darkblue 5, 2 2, 0 1, 1 1, 0 1, 1 0.0277 7380 1 0 1.03 0.35 1.33 0.0151 1730 1 0 1.02 0.933 1.14 0.0555 23600 1 0 1.06 0.0683 9.3 PRS_PLINK_5e.04 327.32 Obstructive sleep apnea Both 18 35 6 neurological darkblue 35, 18 8, 4 9, 3 8, 6 9, 5 0.0381 0.363 0.916 0.038 1.04 0.537 2.01 -0.458 1.07 0.667 0.176 0.632 0.095 3.57 0.869 1.22 0.477 0.321 2.38 0.309 58.8 -0.506 1.15 0.66 0.181 0.603 0.0303 4.43 PRS_PLINK_5e.04 327.4 Insomnia Both 10 35 6 neurological darkblue 35, 10 9, 2 9, 1 8, 4 9, 3 -0.126 0.536 0.815 0.089 0.882 0.3 2.37 0.83 1.61 0.606 0.218 2.29 0.137 95.5 2.86 2.43 0.24 0.62 17.5 0.287 140000 -1.16 1.79 0.517 0.287 0.314 0.00143 6.74 PRS_PLINK_5e.04 327.41 Organic or persistent insomnia Both 3 11 6 neurological darkblue 11, 3 3, 1 3, 0 2, 2 3, 0 -0.682 1.58 0.666 0.176 0.505 0.0239 5.31 0.146 2860000 1 0 1.16 0.359 3.17 0.0504 405 1 0 1.05 0.9 1.47 -0.0697 9590000 1 0 0.933 0.687 1.38 PRS_PLINK_5e.04 327.5 Parasomnia Both 3 9 6 neurological darkblue 9, 3 3, 0 2, 0 2, 3 2, 0 1.89 2.84 0.507 0.295 6.6 0.204 7.73 -0.0423 760 1 0 0.959 0.546 1.63 PRS_PLINK_5e.04 327.6 Circadian rhythm sleep disorder Both 0 6 6 neurological darkblue 6, 0 2 1 1 2 PRS_PLINK_5e.04 327.7 Sleep related movement disorders Both 3 21 6 neurological darkblue 21, 3 6, 2 5, 1 5, 0 5, 0 -0.383 0.72 0.595 0.226 0.682 0.0572 2.35 0.196 2.63 0.941 0.027 1.22 0.000908 873 -0.629 2.09 0.764 0.117 0.533 0.0143 10.4 0.554 2.55 0.828 0.082 1.74 1.57 1.88 PRS_PLINK_5e.04 327.71 Restless legs syndrome Both 2 17 6 neurological darkblue 17, 2 5, 2 4, 0 4, 0 4, 0 -0.381 0.999 0.703 0.153 0.683 0.037 5.25 -0.0913 400 1 0 0.913 0.367 1.42 3.02 49.8 0.952 0.022 20.5 17.1 24.6 -0.0086 58.7 1 0 0.991 0.758 1.13 PRS_PLINK_5e.04 327.72 Sleep related leg cramps Both 0 1 6 neurological darkblue 1, 0 PRS_PLINK_5e.04 331 Other cerebral degenerations Both 2 7 6 neurological darkblue 7, 2 2, 1 2, 1 1, 0 2, 0 0.457 29.5 0.988 0.005 1.58 0.689 1.76 -0.569 8570 1 0 0.566 0.0589 41.4 -7.31 20500 1 0 0.000667 9.48e-19 4.14e+21 0.208 1430 1 0 1.23 0.0991 4.81 PRS_PLINK_5e.04 331.1 Hydrocephalus Both 0 1 6 neurological darkblue 1, 0 PRS_PLINK_5e.04 331.9 Cerebral degeneration, unspecified Both 2 3 6 neurological darkblue 3, 2 1, 2 1, 0 1, 0 1, 2 0.133 2410 1 0 1.14 0.473 3.24 0.00903 10400 1 0 1.01 0.0642 16.9 0.0878 4010 1 0 1.09 0.0363 37.2 PRS_PLINK_5e.04 332 Parkinson's disease Both 0 1 6 neurological darkblue 1, 0 PRS_PLINK_5e.04 333 Extrapyramidal disease and abnormal movement disorders Both 6 27 6 neurological darkblue 27, 6 7, 5 7, 0 6, 1 7, 0 -0.748 0.505 0.139 0.858 0.473 0.128 1.1 -6.92 4.24 0.103 0.987 0.000989 2.63e-20 0.756 -0.094 1.33 0.944 0.025 0.91 0.0649 9.38 -2.15 1.83 0.24 0.619 0.116 1.58e-05 13 PRS_PLINK_5e.04 333.1 Essential tremor Both 1 6 6 neurological darkblue 6, 1 2, 1 1, 0 1, 0 2, 0 -0.0652 348 1 0 0.937 0.782 0.727 0.00284 34.8 1 0 1 0.948 1.05 0.0584 537 1 0 1.06 0.5 2.5 0.178 906 1 0 1.19 0.279 3.99 PRS_PLINK_5e.04 333.2 Myoclonus Both 0 2 6 neurological darkblue 2, 0 1 1 1 1 PRS_PLINK_5e.04 333.4 Torsion dystonia Both 0 4 6 neurological darkblue 4, 0 1 1 1 1 PRS_PLINK_5e.04 333.8 Other degenerative diseases of the basal ganglia Both 1 1 6 neurological darkblue 1, 1 0.00199 44.8 1 0 1 0.951 1.15 PRS_PLINK_5e.04 334 Degenerative disease of the spinal cord Both 0 11 6 neurological darkblue 11, 0 3 3 2 3 PRS_PLINK_5e.04 335 Multiple sclerosis Both 1 3 6 neurological darkblue 3, 1 1, 1 1, 0 1, 0 1, 1 -0.156 8410 1 0 0.855 0.786 11.3 0.00172 53 1 0 1 0.967 1.04 0.00181 28.9 1 0 1 0.951 1.02 PRS_PLINK_5e.04 337 Disorders of the autonomic nervous system Both 8 14 6 neurological darkblue 14, 8 4, 1 3, 4 3, 2 4, 1 -0.713 0.823 0.386 0.413 0.49 0.0681 2 0.148 1.69 0.93 0.032 1.16 0.891 1.27 2.29 3.01 0.445 0.351 9.91 0.118 1080 -0.0901 1.59 0.955 0.02 0.914 0.865 1.02 PRS_PLINK_5e.04 337.1 Peripheral autonomic neuropathy Both 6 11 6 neurological darkblue 11, 6 3, 0 3, 4 2, 0 3, 2 0.0339 1.22 0.978 0.01 1.03 0.038 13.2 0.699 3.01 0.816 0.088 2.01 0.0199 680 1.79 1270 0.999 0 5.96 0.039 446 PRS_PLINK_5e.04 338 Pain Both 36 27 6 neurological darkblue 27, 36 7, 4 7, 17 6, 6 7, 9 -0.0333 0.295 0.91 0.041 0.967 0.564 1.66 1.37 0.846 0.104 0.982 3.95 0.933 21.9 0.481 1.09 0.659 0.181 1.62 0.244 10.9 -0.00381 0.953 0.997 0.001 0.996 0.161 4.85 PRS_PLINK_5e.04 338.1 Acute pain Both 23 27 6 neurological darkblue 27, 23 7, 2 7, 11 6, 2 7, 8 0.0536 0.307 0.862 0.065 1.06 0.606 1.84 2.08 1.27 0.103 0.989 7.97 1.02 472 0.817 1.81 0.652 0.186 2.26 0.0156 1020 0.853 1.14 0.453 0.344 2.35 0.331 24 PRS_PLINK_5e.04 338.2 Chronic pain Both 21 27 6 neurological darkblue 27, 21 7, 4 7, 11 6, 4 7, 2 -0.468 0.396 0.238 0.624 0.626 0.297 1.25 0.768 0.913 0.4 0.398 2.16 0.438 12.7 0.333 1.16 0.775 0.111 1.4 0.183 11 -1.61 1.34 0.231 0.637 0.2 0.00967 1.57 PRS_PLINK_5e.04 339 Other headache syndromes Both 23 36 6 neurological darkblue 36, 23 8, 10 9, 2 9, 4 9, 7 -0.131 0.309 0.671 0.173 0.877 0.486 1.52 -1.37 1.17 0.243 0.614 0.254 0.021 1.8 -0.835 1.01 0.408 0.389 0.434 0.0669 2.43 -0.597 0.864 0.49 0.31 0.55 0.114 2.4 PRS_PLINK_5e.04 340 Migraine Both 19 35 6 neurological darkblue 35, 19 8, 9 9, 3 8, 2 9, 5 -0.37 0.374 0.322 0.492 0.691 0.321 1.32 -1.39 1.08 0.199 0.7 0.249 0.0303 1.49 -2.19 1.73 0.206 0.686 0.112 0.000897 1.75 -1.3 1.43 0.363 0.44 0.273 0.00894 3 PRS_PLINK_5e.04 340.1 Migrain with aura Both 8 25 6 neurological darkblue 25, 8 7, 4 6, 0 6, 1 6, 3 -0.107 0.56 0.849 0.071 0.899 0.271 2.5 -1.66 1.62 0.305 0.515 0.19 4.09e-05 2.1 1.21 1.89 0.522 0.282 3.35 0.162 130 -1.47 2.07 0.477 0.322 0.23 0.00121 8.59 PRS_PLINK_5e.04 342 Hemiplegia Both 0 5 6 neurological darkblue 5, 0 2 1 1 1 PRS_PLINK_5e.04 343 Infantile cerebral palsy Both 0 1 6 neurological darkblue 1, 0 PRS_PLINK_5e.04 344 Other paralytic syndromes Both 1 6 6 neurological darkblue 6, 1 2, 0 1, 0 1, 0 2, 1 0.163 10800000 1 0 1.18 0.00346 372 9.16 3590 0.998 0.001 9460 2.8e-08 7.65e+14 PRS_PLINK_5e.04 345 Epilepsy, recurrent seizures, convulsions Both 5 34 6 neurological darkblue 34, 5 9, 2 8, 1 8, 1 9, 0 -0.699 0.583 0.23 0.638 0.497 0.0917 1.37 -0.00627 1.57 0.997 0.001 0.994 0.0552 25.2 -0.607 1.4 0.665 0.177 0.545 3.73e-05 5.87 -0.87 1.44 0.546 0.263 0.419 0.00299 9.12 PRS_PLINK_5e.04 345.1 Epilepsy Both 1 13 6 neurological darkblue 13, 1 4, 0 3, 1 3, 0 3, 0 -0.534 1.27 0.674 0.171 0.586 0.000124 3.6 -0.322 65.4 0.996 0.002 0.725 0.331 0.642 PRS_PLINK_5e.04 345.11 Generalized convulsive epilepsy Both 1 3 6 neurological darkblue 3, 1 1, 0 1, 0 0, 1 1, 0 0.437 2940 1 0 1.55 0.504 29.4 -0.00113 29.3 1 0 0.999 0.98 1.02 PRS_PLINK_5e.04 345.12 Partial epilepsy Both 1 6 6 neurological darkblue 6, 1 2, 1 1, 0 1, 0 2, 0 0.22 1920 1 0 1.25 0.25 1.55 0.676 19100 1 0 1.97 0.249 168 1.01 9540 1 0 2.74 0.136 7.07 -7.34 11800 1 0 0.000647 6.43e-30 3.25e+14 PRS_PLINK_5e.04 345.3 Convulsions Both 5 32 6 neurological darkblue 32, 5 8, 2 8, 1 8, 1 8, 0 -0.625 0.567 0.271 0.568 0.535 0.103 1.44 0.0425 1.58 0.978 0.009 1.04 0.0762 24.8 -1.29 1.65 0.434 0.362 0.275 0.000344 4.02 -0.705 1.47 0.63 0.2 0.494 0.0347 7.79 PRS_PLINK_5e.04 346 Abnormal findings on study of brain and/or nervous system Both 0 5 6 neurological darkblue 5, 0 2 1 1 1 PRS_PLINK_5e.04 346.1 Nonspecific abnormal findings on radiological and other examination of skull and head Both 3 12 6 neurological darkblue 12, 3 3, 3 3, 0 3, 0 3, 0 -1.1 1.18 0.352 0.454 0.334 0.000387 1.89 -0.293 11.3 0.979 0.009 0.746 0.163 0.172 -2.16 20.5 0.916 0.038 0.115 0.00591 0.0727 -2.9 138 0.983 0.007 0.0549 3.2e-06 0.956 PRS_PLINK_5e.04 346.2 Nonspecific abnormal results of function study of brain and central nervous system Both 0 2 6 neurological darkblue 2, 0 1 1 1 1 PRS_PLINK_5e.04 347 Cataplexy and narcolepsy Both 0 1 6 neurological darkblue 1, 0 PRS_PLINK_5e.04 348 Other conditions of brain Both 2 17 6 neurological darkblue 17, 2 5, 2 4, 0 4, 0 4, 0 -0.407 0.972 0.675 0.171 0.666 0.0482 71.1 -0.904 2.78 0.745 0.128 0.405 0.329 49.4 -0.473 3.07 0.878 0.057 0.623 0.604 0.644 -1.66 4.76 0.727 0.138 0.19 0.000157 330 PRS_PLINK_5e.04 348.2 Cerebral edema and compression of brain Both 1 10 6 neurological darkblue 10, 1 3, 1 2, 0 2, 0 3, 0 -0.197 1.99 0.921 0.036 0.821 0.0267 105 -0.309 1840 1 0 0.734 0.13 3.06 0.0652 442 1 0 1.07 0.838 1.75 12.8 1230 0.992 0.004 373000 1.73e-07 1.39e+18 PRS_PLINK_5e.04 348.4 Cerebral cysts Both 0 4 6 neurological darkblue 4, 0 1 1 1 1 PRS_PLINK_5e.04 348.7 Coma Both 0 2 6 neurological darkblue 2, 0 1 1 1 1 PRS_PLINK_5e.04 348.8 Encephalopathy, not elsewhere classified Both 0 6 6 neurological darkblue 6, 0 2 1 1 2 PRS_PLINK_5e.04 348.9 Other conditions of brain, NOS Both 3 20 6 neurological darkblue 20, 3 5, 0 5, 2 5, 0 5, 1 0.557 0.778 0.474 0.324 1.75 0.417 18.6 0.463 2.85 0.871 0.06 1.59 0.00197 1490 -2.37 19.4 0.903 0.044 0.0935 0.0803 0.109 PRS_PLINK_5e.04 349 Other and unspecified disorders of the nervous system Both 1 10 6 neurological darkblue 10, 1 3, 0 2, 0 2, 1 3, 0 1.49 3.45 0.665 0.177 4.44 0.0205 1310 -0.0609 3110 1 0 0.941 0.00118 28.2 PRS_PLINK_5e.04 350 Abnormal movement Both 12 46 6 neurological darkblue 46, 12 12, 1 11, 3 11, 4 12, 4 0.265 0.438 0.544 0.264 1.3 0.562 3.05 0.605 1.49 0.684 0.165 1.83 0.0608 49.1 1.13 1.14 0.321 0.494 3.1 0.442 52.2 2.3 1.58 0.146 0.835 9.99 0.579 182 PRS_PLINK_5e.04 350.1 Abnormal involuntary movements Both 5 33 6 neurological darkblue 33, 5 9, 0 8, 1 8, 1 8, 3 0.671 0.573 0.242 0.617 1.96 0.699 6.44 -0.028 1.5 0.985 0.007 0.972 0.0291 87 0.843 1.47 0.566 0.247 2.32 0.0387 245 3.44 2.19 0.116 0.937 31.2 0.97 147000 PRS_PLINK_5e.04 350.2 Abnormality of gait Both 8 28 6 neurological darkblue 28, 8 7, 3 7, 1 7, 2 7, 2 0.184 0.649 0.777 0.11 1.2 0.37 4.18 -0.89 1.96 0.65 0.187 0.411 0.00165 16.6 1.68 1.79 0.349 0.457 5.37 0.344 1.24e+08 -1.15 2.51 0.645 0.19 0.315 9.82e-06 22.4 PRS_PLINK_5e.04 350.3 Lack of coordination Both 3 12 6 neurological darkblue 12, 3 3, 1 3, 1 3, 0 3, 1 0.655 0.925 0.479 0.32 1.93 0.459 157 0.671 66.4 0.992 0.004 1.96 2.76 2.58 0.00933 71.4 1 0 1.01 0.638 1.26 1.32 6490000 1 0 3.74 0.612 20 PRS_PLINK_5e.04 350.5 Abnormal reflex Both 0 3 6 neurological darkblue 3, 0 1 1 1 1 PRS_PLINK_5e.04 350.6 Disturbances of sensation of smell and taste Both 0 9 6 neurological darkblue 9, 0 3 2 2 2 PRS_PLINK_5e.04 351 Other peripheral nerve disorders Both 18 39 6 neurological darkblue 39, 18 9, 4 10, 4 9, 4 10, 6 0.226 0.394 0.566 0.247 1.25 0.61 2.67 -0.972 1.1 0.378 0.423 0.378 0.0374 2.43 0.0262 0.961 0.978 0.01 1.03 0.194 6.38 0.351 1.05 0.738 0.132 1.42 0.213 11.4 PRS_PLINK_5e.04 352 Disorders of other cranial nerves Both 2 13 6 neurological darkblue 13, 2 4, 0 3, 0 3, 0 3, 2 0.196 2.12 0.926 0.033 1.22 0.0102 672 1.3 17.6 0.941 0.027 3.69 0.499 3.96 PRS_PLINK_5e.04 352.1 Trigeminal nerve disorders [CN5] Both 1 7 6 neurological darkblue 7, 1 2, 0 2, 0 1, 1 2, 0 0.0183 808 1 0 1.02 0.317 3.6 -5.63 39800 1 0 0.00359 7.63e-10 149000 PRS_PLINK_5e.04 352.2 Facial nerve disorders [CN7] Both 1 5 6 neurological darkblue 5, 1 2, 0 1, 0 1, 0 1, 1 0.168 2680 1 0 1.18 0.561 2.76 -0.00748 35.6 1 0 0.993 0.836 1.05 PRS_PLINK_5e.04 353 Nerve root and plexus disorders Both 3 33 6 neurological darkblue 33, 3 9, 1 8, 1 8, 0 8, 1 0.182 0.603 0.763 0.117 1.2 0.316 4.83 0.189 1.46 0.897 0.047 1.21 0.0607 19 -0.334 1.5 0.824 0.084 0.716 0.0127 11.7 -0.126 1.49 0.933 0.03 0.881 0.0163 46.6 PRS_PLINK_5e.04 353.1 Nerve plexus lesions Both 0 2 6 neurological darkblue 2, 0 1 1 1 1 PRS_PLINK_5e.04 355 Complex regional/central pain syndrome Both 0 6 6 neurological darkblue 6, 0 2 1 1 2 PRS_PLINK_5e.04 355.1 Chronic pain syndrome Both 0 11 6 neurological darkblue 11, 0 3 3 2 3 PRS_PLINK_5e.04 356 Hereditary and idiopathic peripheral neuropathy Both 13 19 6 neurological darkblue 19, 13 5, 2 5, 5 4, 4 5, 2 0.229 0.64 0.72 0.143 1.26 0.376 4.52 -0.677 1.55 0.662 0.179 0.508 0.0288 6.76 0.889 1.79 0.619 0.208 2.43 0.032 159 0.294 2.15 0.892 0.05 1.34 0.00263 179 PRS_PLINK_5e.04 357 Inflammatory and toxic neuropathy Both 14 23 6 neurological darkblue 23, 14 6, 2 6, 3 5, 4 6, 5 0.466 0.533 0.382 0.418 1.59 0.626 5.43 -0.15 1.37 0.912 0.04 0.86 0.0428 9.12 0.984 1.81 0.587 0.231 2.67 0.138 928 0.802 1.69 0.635 0.197 2.23 0.00602 270 PRS_PLINK_5e.04 358 Myoneural disorders Both 3 5 6 neurological darkblue 5, 3 2, 1 1, 1 1, 0 1, 1 -0.00169 51.8 1 0 0.998 0.569 1.1 0.019 666 1 0 1.02 0.922 1.25 -0.143 2870 1 0 0.867 0.286 1.45 -0.129 1600 1 0 0.879 0.319 1.12 PRS_PLINK_5e.04 359 Muscular dystrophies and other myopathies Both 5 12 6 neurological darkblue 12, 5 3, 0 3, 3 3, 0 3, 2 0.895 1.37 0.513 0.29 2.45 0.2 66.5 -0.281 101 0.998 0.001 0.755 0.205 3.43 0.361 1840 1 0 1.44 0.543 6.1 PRS_PLINK_5e.04 359.2 Myopathy Both 5 10 6 neurological darkblue 10, 5 3, 0 2, 3 2, 1 3, 1 1.13 1.43 0.429 0.367 3.09 0.125 51.9 0.0178 1070 1 0 1.02 0.899 2.2 -5.32 2.87e+08 1 0 0.00487 1.47e-10 205000 0.129 2280 1 0 1.14 0.538 1.34 PRS_PLINK_5e.04 360.2 Progressive myopia Both 0 1 7 sense organs darkseagreen4 1, 0 PRS_PLINK_5e.04 361 Retinal detachments and defects Both 0 10 7 sense organs darkseagreen4 10, 0 3 2 2 3 PRS_PLINK_5e.04 361.1 Retinal detachment with retinal defect Both 0 6 7 sense organs darkseagreen4 6, 0 2 1 1 2 PRS_PLINK_5e.04 362 Other retinal disorders Both 11 16 7 sense organs darkseagreen4 16, 11 3, 3 4, 3 4, 1 4, 4 0.175 0.515 0.734 0.134 1.19 0.484 2.95 -1.08 3.26 0.741 0.13 0.34 0.000126 107 -0.978 2.29 0.669 0.174 0.376 0.00478 329 0.326 2.26 0.885 0.053 1.39 0.00122 44.4 PRS_PLINK_5e.04 362.2 Degeneration of macula and posterior pole of retina Both 3 10 7 sense organs darkseagreen4 10, 3 3, 1 2, 0 2, 1 3, 1 -1.1 1.98 0.578 0.238 0.333 0.00838 7.31 -0.36 3750 1 0 0.698 0.00412 1.05e+09 0.283 900 1 0 1.33 0.943 3.01 1.07 496 0.998 0.001 2.92 0.0622 778 PRS_PLINK_5e.04 362.21 Macular degeneration, dry Both 0 2 7 sense organs darkseagreen4 2, 0 1 1 1 1 PRS_PLINK_5e.04 362.22 Macular degeneration, wet Both 0 1 7 sense organs darkseagreen4 1, 0 PRS_PLINK_5e.04 362.23 Cystoid macular degeneration of retina Both 0 4 7 sense organs darkseagreen4 4, 0 1 1 1 1 PRS_PLINK_5e.04 362.26 Macular puckering of retina Both 2 7 7 sense organs darkseagreen4 7, 2 2, 0 2, 0 1, 1 2, 1 -0.087 63.5 0.999 0 0.917 0.277 1.84 0.683 1220 1 0 1.98 0.504 10.1 4.7 5280 0.999 0 110 0.000234 5030000 PRS_PLINK_5e.04 362.27 Drusen (degenerative) of retina Both 1 3 7 sense organs darkseagreen4 3, 1 1, 1 1, 0 1, 0 1, 1 0.234 2820 1 0 1.26 0.522 1.55 0.0397 841 1 0 1.04 0.905 1.41 0.214 4380 1 0 1.24 0.622 1.3 PRS_PLINK_5e.04 362.29 Macular degeneration (senile) of retina NOS Both 3 10 7 sense organs darkseagreen4 10, 3 3, 1 2, 0 2, 1 3, 1 -1.1 1.98 0.578 0.238 0.333 0.00838 7.31 -0.36 3750 1 0 0.698 0.00412 1.05e+09 0.283 900 1 0 1.33 0.943 3.01 1.07 496 0.998 0.001 2.92 0.0622 778 PRS_PLINK_5e.04 362.3 Other nondiabetic retinopathy Both 3 9 7 sense organs darkseagreen4 9, 3 2, 2 2, 0 2, 0 2, 1 0.528 1.31 0.686 0.164 1.69 0.254 13.6 -0.509 3800 1 0 0.601 0.446 3.18 0.152 1080 1 0 1.16 0.726 5.06 0.0653 260 1 0 1.07 0.844 1.85 PRS_PLINK_5e.04 362.31 Separation of retinal layers Both 0 4 7 sense organs darkseagreen4 4, 0 1 1 1 1 PRS_PLINK_5e.04 362.4 Retinal vascular changes and abnomalities Both 4 3 7 sense organs darkseagreen4 3, 4 1, 2 1, 0 1, 2 1, 2 0.00418 155 1 0 1 0.577 3.69 -0.104 2630 1 0 0.901 0.699 1.5 0.00458 301 1 0 1 0.88 1.4 PRS_PLINK_5e.04 362.6 Peripheral retinal degenerations Both 2 4 7 sense organs darkseagreen4 4, 2 1, 2 1, 0 1, 0 1, 0 -0.0899 187 1 0 0.914 0.589 1.22 -0.0016 170 1 0 0.998 0.222 7.95 -0.0999 732 1 0 0.905 0.89 1.14 -0.0232 1030 1 0 0.977 0.753 1.13 PRS_PLINK_5e.04 362.7 Hereditary retinal dystrophies Both 1 0 7 sense organs darkseagreen4 0, 1 PRS_PLINK_5e.04 362.8 Retinal hemorrhage/ischemia Both 0 2 7 sense organs darkseagreen4 2, 0 1 1 1 1 PRS_PLINK_5e.04 362.9 Retinal edema Both 1 4 7 sense organs darkseagreen4 4, 1 1, 1 1, 0 1, 0 1, 0 -0.141 2860 1 0 0.868 0.769 1.37 -0.00029 40 1 0 1 0.961 1.04 0.0108 38.1 1 0 1.01 0.903 1.23 0.00632 4640 1 0 1.01 0.847 1.72 PRS_PLINK_5e.04 363 Chorioretinal inflammations, scars, and other disorders of choroid Both 0 7 7 sense organs darkseagreen4 7, 0 2 2 1 2 PRS_PLINK_5e.04 363.3 Chorioretinal scars Both 0 5 7 sense organs darkseagreen4 5, 0 2 1 1 1 PRS_PLINK_5e.04 364 Corneal opacity and other disorders of cornea Both 4 15 7 sense organs darkseagreen4 15, 4 4, 0 4, 0 3, 2 4, 2 0.865 1.08 0.424 0.372 2.37 0.353 1250 -0.0291 613 1 0 0.971 0.278 3.03 1.19 11.2 0.915 0.039 3.3 3.03 3.59 PRS_PLINK_5e.04 364.1 Corneal opacity Both 2 8 7 sense organs darkseagreen4 8, 2 2, 0 2, 0 2, 1 2, 1 -0.42 2 0.834 0.079 0.657 0.0266 12.1 -0.00151 92.8 1 0 0.998 0.114 71.7 0.32 1530 1 0 1.38 0.0156 56.5 PRS_PLINK_5e.04 364.2 Corneal edema Both 1 2 7 sense organs darkseagreen4 2, 1 1, 0 0, 1 1, 0 1, 0 -4.97 8750 1 0 0.00695 1.49e-10 16700 0.0311 34.9 0.999 0 1.03 0.966 1.31 PRS_PLINK_5e.04 364.4 Corneal degenerations Both 3 5 7 sense organs darkseagreen4 5, 3 2, 0 1, 0 1, 0 1, 3 -0.608 2.3e+07 1 0 0.545 0.0343 39400 -0.781 4880 1 0 0.458 0.197 7.41 PRS_PLINK_5e.04 364.5 Corneal dystrophy Both 1 4 7 sense organs darkseagreen4 4, 1 1, 0 1, 0 1, 0 1, 1 -0.122 21200 1 0 0.885 0.425 2.02 -0.0202 45.8 1 0 0.98 0.862 1.06 PRS_PLINK_5e.04 365 Glaucoma Both 10 23 7 sense organs darkseagreen4 23, 10 5, 3 6, 3 5, 2 6, 2 -0.573 0.563 0.309 0.51 0.564 0.158 1.48 0.328 1.51 0.828 0.082 1.39 0.109 17.4 0.135 1.51 0.929 0.032 1.14 0.0315 24.1 -0.482 1.36 0.724 0.14 0.618 0.00555 5.44 PRS_PLINK_5e.04 365.1 Open-angle glaucoma Both 3 6 7 sense organs darkseagreen4 6, 3 2, 1 1, 1 1, 0 2, 1 -2.7 26.4 0.918 0.037 0.0669 0.0082 0.0104 -0.396 4850 1 0 0.673 0.0152 28.7 0.276 14300 1 0 1.32 0.273 23 -0.288 7030 1 0 0.75 0.369 1.86 PRS_PLINK_5e.04 365.11 Primary open angle glaucoma Both 1 3 7 sense organs darkseagreen4 3, 1 1, 1 1, 0 1, 0 1, 1 -0.017 307 1 0 0.983 0.911 1.06 -0.0189 2840 1 0 0.981 0.964 1.07 -0.0389 2340 1 0 0.962 0.709 1.4 PRS_PLINK_5e.04 365.2 Primary angle-closure glaucoma Both 0 2 7 sense organs darkseagreen4 2, 0 1 1 1 1 PRS_PLINK_5e.04 366 Cataract Both 22 22 7 sense organs darkseagreen4 22, 22 5, 4 5, 6 5, 2 6, 10 0.685 0.539 0.204 0.69 1.98 0.717 9.53 -1.16 1.66 0.486 0.314 0.315 0.000549 4.62 -0.692 1.53 0.651 0.186 0.501 0.038 5.61 0.603 1.23 0.624 0.204 1.83 0.2 60 PRS_PLINK_5e.04 366.1 Nonsenile Cataract Both 2 0 7 sense organs darkseagreen4 0, 2 PRS_PLINK_5e.04 366.2 Senile cataract Both 19 18 7 sense organs darkseagreen4 18, 19 4, 4 4, 6 4, 2 5, 7 0.534 0.635 0.4 0.398 1.71 0.426 11.4 -1.08 1.67 0.516 0.287 0.339 0.000238 5.95 0.222 2.01 0.912 0.04 1.25 0.0599 2080 -0.639 1.63 0.695 0.158 0.528 0.00387 17.8 PRS_PLINK_5e.04 367 Disorders of refraction and accommodation; blindness and low vision Both 25 39 7 sense organs darkseagreen4 39, 25 9, 6 10, 8 9, 5 10, 6 -0.102 0.327 0.755 0.122 0.903 0.484 1.64 -0.818 1.02 0.421 0.375 0.441 0.0448 2.56 -0.402 0.993 0.686 0.164 0.669 0.0966 4.21 -1.01 1.13 0.369 0.433 0.364 0.0232 2.55 PRS_PLINK_5e.04 367.1 Myopia Both 22 36 7 sense organs darkseagreen4 36, 22 8, 6 9, 7 9, 4 9, 5 -0.102 0.333 0.759 0.119 0.903 0.477 1.66 -1.1 1.12 0.323 0.491 0.332 0.0262 2.21 -0.504 0.996 0.613 0.212 0.604 0.0967 3.53 -2.67 1.71 0.118 0.928 0.0691 0.000219 1.23 PRS_PLINK_5e.04 367.2 Astigmatism Both 12 32 7 sense organs darkseagreen4 32, 12 7, 2 8, 3 8, 3 8, 4 0.143 0.423 0.735 0.134 1.15 0.508 2.58 -1.01 1.47 0.492 0.308 0.364 0.00709 4.11 -0.76 1.51 0.616 0.211 0.468 0.00482 5.24 -1.27 1.54 0.409 0.388 0.281 0.0112 3.43 PRS_PLINK_5e.04 367.8 Hypermetropia Both 0 17 7 sense organs darkseagreen4 17, 0 4 4 4 4 PRS_PLINK_5e.04 367.9 Blindness and low vision Both 3 14 7 sense organs darkseagreen4 14, 3 4, 2 3, 0 3, 0 4, 1 -1.98 1.76 0.262 0.582 0.138 0.114 3.05 -2.81 35.1 0.936 0.029 0.0601 0.05 0.0726 -0.697 58.3 0.99 0.004 0.498 4.12e-05 0.22 6.41 19.2 0.738 0.132 610 366 951 PRS_PLINK_5e.04 368 Visual disturbances Both 15 46 7 sense organs darkseagreen4 46, 15 11, 7 11, 5 11, 1 12, 2 -0.287 0.372 0.44 0.356 0.75 0.358 1.47 -0.425 0.874 0.627 0.203 0.654 0.109 3.1 -0.917 1.19 0.441 0.356 0.4 0.0174 3.15 -1.49 1.2 0.213 0.671 0.226 0.0101 1.61 PRS_PLINK_5e.04 368.1 Amblyopia Both 2 11 7 sense organs darkseagreen4 11, 2 3, 0 3, 0 2, 0 3, 2 0.805 1.32 0.543 0.265 2.24 0.0848 29.4 0.0832 114 0.999 0 1.09 1.47 0.993 PRS_PLINK_5e.04 368.2 Diplopia and disorders of binocular vision Both 7 13 7 sense organs darkseagreen4 13, 7 4, 1 3, 2 3, 2 3, 2 1.02 1 0.308 0.512 2.78 0.539 27.2 -0.877 2.12 0.679 0.168 0.416 0.0269 9.54 0.839 3.05 0.784 0.106 2.31 2.12 2.69 -2.82 5.34 0.597 0.224 0.0596 0.0476 272 PRS_PLINK_5e.04 368.3 Anisometropia Both 0 3 7 sense organs darkseagreen4 3, 0 1 1 1 1 PRS_PLINK_5e.04 368.4 Visual field defects Both 3 12 7 sense organs darkseagreen4 12, 3 3, 0 3, 1 3, 0 3, 2 0.606 1.12 0.588 0.231 1.83 0.297 158 -0.132 227 1 0 0.876 0.409 1.07 0.366 488 0.999 0 1.44 3.57 33.8 PRS_PLINK_5e.04 368.9 Subjective visual disturbances Both 3 11 7 sense organs darkseagreen4 11, 3 3, 2 3, 0 2, 0 3, 1 0.267 1.24 0.83 0.081 1.31 0.0318 38.9 -0.0962 7990 1 0 0.908 0.471 1.85 -0.742 395 0.999 0.001 0.476 0.0729 0.159 2.09 93.3 0.982 0.008 8.08 0.00744 4500 PRS_PLINK_5e.04 368.91 Psychophysical visual disturbances Both 0 1 7 sense organs darkseagreen4 1, 0 PRS_PLINK_5e.04 369 Infection of the eye Both 8 38 7 sense organs darkseagreen4 38, 8 9, 0 9, 1 9, 3 10, 4 0.743 0.559 0.184 0.736 2.1 0.732 14.4 0.422 2.02 0.835 0.079 1.52 0.00512 213 1.25 2 0.533 0.273 3.48 0.0674 311000 0.253 1.76 0.886 0.053 1.29 0.0377 329 PRS_PLINK_5e.04 369.2 Eye infection, viral Both 1 11 7 sense organs darkseagreen4 11, 1 3, 0 3, 1 2, 0 3, 0 -0.632 3 0.833 0.079 0.532 0.00374 120 -0.177 681 1 0 0.838 0.298 2.58 PRS_PLINK_5e.04 369.5 Conjunctivitis, infectious Both 6 32 7 sense organs darkseagreen4 32, 6 7, 0 8, 0 8, 2 8, 4 0.825 0.588 0.16 0.796 2.28 0.776 87.9 0.336 2 0.867 0.062 1.4 0.00978 16400 0.586 2.19 0.789 0.103 1.8 0.0409 1020 PRS_PLINK_5e.04 370 Keratitis Both 4 18 7 sense organs darkseagreen4 18, 4 5, 1 4, 2 4, 0 5, 1 0.659 1.08 0.54 0.267 1.93 0.00239 22.6 -1.31 2.43 0.59 0.229 0.271 2.41e-05 8.16 -13.3 1690 0.994 0.003 1.63e-06 4.15e-30 1.75e-06 0.0504 1.8 0.978 0.01 1.05 0.0276 15.7 PRS_PLINK_5e.04 370.1 Corneal ulcer Both 0 6 7 sense organs darkseagreen4 6, 0 2 1 1 2 PRS_PLINK_5e.04 370.2 Superficial keratitis Both 2 7 7 sense organs darkseagreen4 7, 2 2, 2 2, 0 1, 0 2, 0 0.313 320 0.999 0 1.37 0.648 1.39 0.818 2030 1 0 2.27 0.337 167 0.00131 154 1 0 1 0.982 1.02 0.355 5450 1 0 1.43 0.396 2.09 PRS_PLINK_5e.04 370.3 Keratoconjunctivitis Both 2 8 7 sense organs darkseagreen4 8, 2 2, 1 2, 0 2, 0 2, 1 -0.0161 635 1 0 0.984 0.618 1.28 0.0159 4850 1 0 1.02 0.323 7.13 0.0145 702 1 0 1.01 0.746 1.45 0.00129 40.6 1 0 1 0.842 1.11 PRS_PLINK_5e.04 370.31 Keratoconjunctivitis sicca Both 0 4 7 sense organs darkseagreen4 4, 0 1 1 1 1 PRS_PLINK_5e.04 371 Inflammation of the eye Both 11 35 7 sense organs darkseagreen4 35, 11 8, 3 9, 1 8, 4 9, 3 -0.153 0.465 0.742 0.13 0.858 0.346 1.99 -1.92 1.69 0.256 0.591 0.146 0.00325 2.51 -0.823 1.4 0.556 0.255 0.439 0.0181 6.43 -1.13 1.38 0.413 0.384 0.322 0.00672 4.25 PRS_PLINK_5e.04 371.1 Uveitis, noninfectious or NOS Both 2 9 7 sense organs darkseagreen4 9, 2 3, 1 2, 1 2, 0 2, 0 -0.0188 427 1 0 0.981 0.693 1.03 -0.161 2250 1 0 0.851 0.694 2.68 0.207 2720 1 0 1.23 0.491 4.3 -0.181 5600 1 0 0.834 0.227 2.74 PRS_PLINK_5e.04 371.2 Conjunctivitis, noninfectious Both 1 16 7 sense organs darkseagreen4 16, 1 4, 1 4, 0 4, 0 4, 0 -0.444 1.27 0.726 0.139 0.642 9.34e-05 4.81 0.465 4.66 0.921 0.036 1.59 1.27 1.85 -1.86 4.95 0.706 0.151 0.155 0.152 0.157 0.12 1670 1 0 1.13 1.3 3.41 PRS_PLINK_5e.04 371.21 Allergic conjunctivitis Both 1 15 7 sense organs darkseagreen4 15, 1 4, 1 4, 0 3, 0 4, 0 -1.22 1.98 0.539 0.269 0.296 1.59e-05 6.57 -0.474 27.7 0.986 0.006 0.622 0.139 3.93 -0.0993 815 1 0 0.906 0.103 0.198 -0.922 1.6e+07 1 0 0.398 0.00186 135 PRS_PLINK_5e.04 371.3 Inflammation of eyelids Both 8 25 7 sense organs darkseagreen4 25, 8 6, 1 6, 1 6, 3 6, 3 0.366 0.601 0.542 0.266 1.44 0.502 4.58 0.15 2.73 0.956 0.019 1.16 0.000334 196 0.725 2.01 0.718 0.144 2.06 0.0319 2810 -0.226 1.91 0.906 0.043 0.798 0.0143 59.1 PRS_PLINK_5e.04 372 Disorders of conjunctiva Both 4 13 7 sense organs darkseagreen4 13, 4 4, 0 3, 0 3, 1 3, 3 1.86 1.22 0.126 0.898 6.41 1.15 187 -0.172 610 1 0 0.842 0.0132 9.46 0.634 152 0.997 0.001 1.88 0.00593 412 PRS_PLINK_5e.04 374 Other disorders of eyelids Both 9 22 7 sense organs darkseagreen4 22, 9 6, 2 5, 4 5, 2 6, 1 -0.161 0.558 0.773 0.112 0.852 0.291 2.23 4.81 3.92 0.22 0.658 123 0.412 3.76e+09 0.745 2 0.709 0.149 2.11 0.0243 887 -0.787 2.45 0.748 0.126 0.455 0.00139 230 PRS_PLINK_5e.04 374.1 Ectropion or entropion Both 1 5 7 sense organs darkseagreen4 5, 1 2, 1 1, 0 1, 0 1, 0 -0.287 4030 1 0 0.75 0.574 2.51 -0.00863 858 1 0 0.991 0.839 1.15 -0.0178 1560 1 0 0.982 0.696 1.35 -0.0741 8010 1 0 0.929 0.237 11 PRS_PLINK_5e.04 374.2 Lagophthalmos Both 1 3 7 sense organs darkseagreen4 3, 1 1, 0 1, 0 1, 1 1, 0 -5.48 11400 1 0 0.00417 5.51e-13 157000 0.273 15100 1 0 1.31 0.182 7.58 PRS_PLINK_5e.04 374.3 Ptosis of eyelid Both 2 7 7 sense organs darkseagreen4 7, 2 2, 0 2, 1 1, 0 2, 1 -0.0799 3.13 0.98 0.009 0.923 0.886 0.947 0.114 16300 1 0 1.12 0.243 5.53 -0.0234 184 1 0 0.977 0.961 1.13 PRS_PLINK_5e.04 374.6 Dermatochalasis Both 1 9 7 sense organs darkseagreen4 9, 1 3, 0 2, 0 2, 1 2, 0 0.17 27.4 0.995 0.002 1.19 0.866 1270 -0.19 6910 1 0 0.827 0.748 5.22 PRS_PLINK_5e.04 375 Disorders of lacrimal system Both 12 25 7 sense organs darkseagreen4 25, 12 6, 5 6, 2 6, 2 6, 3 -0.137 0.474 0.773 0.112 0.872 0.345 2.08 0.505 1.6 0.753 0.123 1.66 0.0855 36.4 0.291 1.84 0.874 0.058 1.34 0.0262 81.4 -0.83 1.83 0.651 0.187 0.436 0.000215 6.02 PRS_PLINK_5e.04 375.1 Dry eyes Both 14 24 7 sense organs darkseagreen4 24, 14 5, 6 6, 3 6, 2 6, 3 -0.272 0.433 0.53 0.276 0.762 0.342 1.63 -1.21 1.41 0.391 0.407 0.298 0.0127 2.69 0.396 1.73 0.819 0.087 1.49 0.00802 128 -0.83 1.83 0.651 0.187 0.436 0.000215 6.02 PRS_PLINK_5e.04 375.2 Epiphora Both 1 7 7 sense organs darkseagreen4 7, 1 2, 0 2, 1 1, 0 2, 0 -0.31 378 0.999 0 0.734 1.31 1.15 0.0776 1340 1 0 1.08 0.00325 5320 PRS_PLINK_5e.04 376 Disorders of the orbit Both 1 4 7 sense organs darkseagreen4 4, 1 1, 1 1, 0 1, 0 1, 0 0.969 1.48e+08 1 0 2.64 0.000241 33.7 -0.00427 324 1 0 0.996 0.928 1.06 -0.000618 25.2 1 0 0.999 0.989 1.02 -0.00841 33.4 1 0 0.992 0.891 1.22 PRS_PLINK_5e.04 377 Disorders of optic nerve and visual pathways Both 3 10 7 sense organs darkseagreen4 10, 3 3, 0 2, 2 2, 0 3, 1 0.709 2.76 0.797 0.098 2.03 0.0337 2.24 -0.115 4990 1 0 0.891 0.861 1.83 0.0924 783 1 0 1.1 0.275 2.18 PRS_PLINK_5e.04 377.1 Optic atrophy Both 2 3 7 sense organs darkseagreen4 3, 2 1, 0 1, 1 1, 1 1, 0 0.625 2690 1 0 1.87 0.63 145 0.0483 318 1 0 1.05 0.775 1.09 10.5 24500 1 0 34800 2.07e-14 5.08e+22 PRS_PLINK_5e.04 377.3 Optic neuritis/neuropathy Both 2 5 7 sense organs darkseagreen4 5, 2 2, 0 1, 1 1, 1 1, 0 0.0894 43.2 0.998 0.001 1.09 0.286 2.88 0.0288 3.9e+08 1 0 1.03 1.18e-05 9.4 0.123 3180 1 0 1.13 0.486 2.89 PRS_PLINK_5e.04 378 Strabismus and other disorders of binocular eye movements Both 6 13 7 sense organs darkseagreen4 13, 6 3, 1 3, 2 3, 2 3, 1 0.323 0.72 0.654 0.185 1.38 0.423 5.4 0.0774 4.49 0.986 0.006 1.08 1.24 1.25 1.18 12.7 0.926 0.033 3.27 5.17 7.02 -0.319 523 1 0 0.727 0.124 0.609 PRS_PLINK_5e.04 378.1 Strabismus (not specified as paralytic) Both 5 11 7 sense organs darkseagreen4 11, 5 2, 2 3, 1 2, 1 3, 1 0.105 0.787 0.894 0.049 1.11 0.204 4.72 -0.379 1860 1 0 0.685 0.138 1.62 0.106 97.8 0.999 0 1.11 1.08 1.36 0.0464 1750 1 0 1.05 0.384 4.78 PRS_PLINK_5e.04 378.2 Nystagmus and other irregular eye movements Both 1 3 7 sense organs darkseagreen4 3, 1 1, 0 1, 0 1, 1 1, 0 0.311 14700 1 0 1.36 0.365 7.13 -0.432 19000 1 0 0.649 0.0203 11.6 PRS_PLINK_5e.04 378.5 Paralytic strabismus Both 1 3 7 sense organs darkseagreen4 3, 1 1, 1 1, 0 1, 0 1, 1 0.0635 1140 1 0 1.07 0.852 1.16 0.000653 85.7 1 0 1 0.987 1.01 5.09e-06 8.82 1 0 1 0.996 1 PRS_PLINK_5e.04 379 Other disorders of eye Both 19 26 7 sense organs darkseagreen4 26, 19 6, 6 6, 9 6, 0 7, 4 -0.0872 0.416 0.834 0.079 0.916 0.425 1.93 0.0651 1.13 0.954 0.02 1.07 0.127 8.03 -1.35 2.18 0.535 0.272 0.259 4.22e-05 6.69 -1.37 1.31 0.294 0.531 0.254 0.016 1.83 PRS_PLINK_5e.04 379.1 Scleritis and episcleritis Both 0 3 7 sense organs darkseagreen4 3, 0 1 1 1 1 PRS_PLINK_5e.04 379.2 Disorders of vitreous body Both 16 16 7 sense organs darkseagreen4 16, 16 3, 5 4, 7 4, 0 4, 4 0.098 0.516 0.849 0.071 1.1 0.451 2.76 0.337 1.5 0.822 0.085 1.4 0.0724 18.3 -0.477 3.51 0.892 0.05 0.621 0.00249 1680 -1.33 1.54 0.388 0.411 0.265 0.00603 2.44 PRS_PLINK_5e.04 379.3 Aphakia and other disorders of lens Both 0 5 7 sense organs darkseagreen4 5, 0 2 1 1 1 PRS_PLINK_5e.04 379.4 Anomalies of pupillary function Both 1 2 7 sense organs darkseagreen4 2, 1 1, 0 0, 1 1, 0 1, 0 -0.00148 440 1 0 0.999 0.752 1.22 -0.000149 48.5 1 0 1 0.969 1 PRS_PLINK_5e.04 379.5 Disorders of iris and ciliary body Both 0 3 7 sense organs darkseagreen4 3, 0 1 1 1 1 PRS_PLINK_5e.04 379.9 Pain, swelling or discharge of eye Both 6 18 7 sense organs darkseagreen4 18, 6 5, 1 4, 4 4, 1 5, 0 -0.388 0.688 0.572 0.242 0.678 0.192 2.07 5.25 4.6 0.254 0.594 190 0.409 4.14e+10 1.06 4.08 0.796 0.099 2.87 3.32e-05 13500 -3.13 5.34 0.558 0.253 0.0438 9.49e-06 128 PRS_PLINK_5e.04 380 Disorders of external ear Both 6 22 7 sense organs darkseagreen4 22, 6 6, 1 5, 2 5, 2 6, 1 -0.142 0.866 0.87 0.061 0.867 0.151 4.16 -0.408 2.12 0.848 0.072 0.665 0.00842 75.9 3.2 6.05 0.597 0.224 24.5 0.00233 2.5e+07 0.256 2.56 0.92 0.036 1.29 0.000359 1950 PRS_PLINK_5e.04 380.1 Otitis externa Both 2 26 7 sense organs darkseagreen4 26, 2 6, 0 6, 0 6, 2 7, 0 -0.0545 0.647 0.933 0.03 0.947 0.0363 3.91 0.0388 67.2 1 0 1.04 0.921 2.25 PRS_PLINK_5e.04 380.4 Impacted cerumen Both 6 28 7 sense organs darkseagreen4 28, 6 7, 2 7, 1 7, 3 7, 0 -0.219 0.641 0.733 0.135 0.804 0.181 2.56 0.53 1.75 0.762 0.118 1.7 0.0874 18000 1.59 2.5 0.525 0.28 4.89 0.0169 994000 -0.208 1.6 0.896 0.047 0.812 0.0315 59 PRS_PLINK_5e.04 381 Otitis media and Eustachian tube disorders Both 7 50 7 sense organs darkseagreen4 50, 7 12, 3 12, 1 12, 1 13, 2 0.169 0.405 0.676 0.17 1.18 0.515 2.65 -0.508 1.4 0.717 0.144 0.602 0.0116 16.7 -1.31 1.28 0.307 0.512 0.271 0.00451 2.39 -1.12 1.42 0.429 0.368 0.326 2.5e-05 7.13 PRS_PLINK_5e.04 381.1 Otitis media Both 5 45 7 sense organs darkseagreen4 45, 5 11, 1 11, 1 11, 1 11, 2 0.482 0.464 0.3 0.524 1.62 0.648 4.77 -0.0802 1.74 0.963 0.016 0.923 0.00606 34.1 -0.599 1.49 0.687 0.163 0.549 0.002 9.95 0.787 1.57 0.615 0.211 2.2 0.00117 17100 PRS_PLINK_5e.04 381.11 Suppurative and unspecified otitis media Both 4 37 7 sense organs darkseagreen4 37, 4 9, 0 9, 1 9, 1 9, 2 0.461 0.48 0.337 0.473 1.59 0.614 4.76 0.8 2.12 0.707 0.151 2.22 0.00462 487 0.0438 2.35 0.985 0.007 1.04 0.00187 1380 1.13 1.96 0.565 0.248 3.1 0.00588 3400 PRS_PLINK_5e.04 381.2 Eustachian tube disorders Both 4 31 7 sense organs darkseagreen4 31, 4 8, 3 8, 1 7, 0 8, 0 -1.24 0.958 0.194 0.712 0.288 0.000256 1.84 -0.64 1.69 0.705 0.152 0.527 0.0107 66.7 -0.175 1.59 0.913 0.04 0.84 0.0224 43.2 -1.16 2.01 0.566 0.247 0.315 2.57e-05 23.3 PRS_PLINK_5e.04 381.3 Mastoiditis & related conditions Both 0 5 7 sense organs darkseagreen4 5, 0 2 1 1 1 PRS_PLINK_5e.04 381.9 Otorrhea Both 0 5 7 sense organs darkseagreen4 5, 0 2 1 1 1 PRS_PLINK_5e.04 382 Otalgia Both 4 29 7 sense organs darkseagreen4 29, 4 8, 0 7, 2 7, 1 7, 1 0.323 0.898 0.719 0.143 1.38 0.139 148 0.504 1.93 0.794 0.1 1.65 0.0112 242 0.996 2.92 0.733 0.135 2.71 1.62e-05 309 0.0543 2.17 0.98 0.009 1.06 0.00301 259 PRS_PLINK_5e.04 383 Otosclerosis Both 0 4 7 sense organs darkseagreen4 4, 0 1 1 1 1 PRS_PLINK_5e.04 384 Other disorders of tympanic membrane Both 1 5 7 sense organs darkseagreen4 5, 1 2, 1 1, 0 1, 0 1, 0 0.213 3040 1 0 1.24 0.0797 4.54 5.14 20600 1 0 171 7.49e-18 1.39e+26 -0.125 8560 1 0 0.883 0.369 7.37 -0.13 11000 1 0 0.878 0.0405 112 PRS_PLINK_5e.04 384.1 Myringitis Both 0 2 7 sense organs darkseagreen4 2, 0 1 1 1 1 PRS_PLINK_5e.04 384.4 Perforation of tympanic membrane Both 1 1 7 sense organs darkseagreen4 1, 1 -0.106 1.86e+10 1 0 0.9 1.4e-21 1.18e+27 PRS_PLINK_5e.04 385 Other disorders of middle ear and mastoid Both 0 6 7 sense organs darkseagreen4 6, 0 2 1 1 2 PRS_PLINK_5e.04 385.3 Cholesteatoma Both 0 4 7 sense organs darkseagreen4 4, 0 1 1 1 1 PRS_PLINK_5e.04 385.5 Tympanosclerosis and middle ear disease related to otitis media Both 0 3 7 sense organs darkseagreen4 3, 0 1 1 1 1 PRS_PLINK_5e.04 386 Vertiginous syndromes and other disorders of vestibular system Both 4 23 7 sense organs darkseagreen4 23, 4 6, 0 6, 1 5, 1 6, 2 0.297 0.661 0.653 0.185 1.35 0.384 7.38 -0.0064 2.61 0.998 0.001 0.994 0.00358 394 1.64 2.35 0.486 0.314 5.16 0.204 308 0.879 2.81 0.754 0.122 2.41 0.0391 362 PRS_PLINK_5e.04 386.1 Meniere's disease Both 0 2 7 sense organs darkseagreen4 2, 0 1 1 1 1 PRS_PLINK_5e.04 386.2 Peripheral or central vertigo Both 4 17 7 sense organs darkseagreen4 17, 4 5, 0 4, 1 4, 1 4, 2 0.363 0.858 0.673 0.172 1.44 0.322 6.85 0.0446 1810000 1 0 1.05 0.256 1.52 2.46 82.7 0.976 0.01 11.6 0.0343 3570 3.29 6.59 0.618 0.209 26.8 0.000837 2510000 PRS_PLINK_5e.04 386.21 Central origin vertigo Both 3 14 7 sense organs darkseagreen4 14, 3 4, 0 3, 1 3, 0 4, 2 0.425 0.835 0.61 0.215 1.53 0.197 6.82 -0.0532 1190000 1 0 0.948 0.314 1.72 0.0708 7.74 0.993 0.003 1.07 0.000119 45400 PRS_PLINK_5e.04 386.3 Labyrinthitis Both 3 19 7 sense organs darkseagreen4 19, 3 5, 0 5, 1 4, 0 5, 2 0.34 0.778 0.662 0.179 1.4 0.205 8.81 0.0721 6.37 0.991 0.004 1.07 1.07 1.08 1.03 2.8 0.713 0.147 2.8 0.0489 1250 PRS_PLINK_5e.04 386.9 Dizziness and giddiness (Light-headedness and vertigo) Both 12 46 7 sense organs darkseagreen4 46, 12 11, 3 11, 5 11, 1 12, 3 -0.118 0.425 0.781 0.107 0.889 0.366 1.95 1.03 1.21 0.396 0.402 2.8 0.341 39.7 -0.854 1.23 0.489 0.311 0.426 0.0207 4.68 -0.427 1.06 0.688 0.163 0.652 0.0592 4.27 PRS_PLINK_5e.04 388 Other disorders of ear Both 0 7 7 sense organs darkseagreen4 7, 0 2 2 1 2 PRS_PLINK_5e.04 389 Hearing loss Both 13 49 7 sense organs darkseagreen4 49, 13 13, 4 12, 4 12, 2 12, 3 -0.23 0.417 0.58 0.236 0.794 0.334 1.74 -0.506 0.972 0.603 0.22 0.603 0.0854 3.43 -0.63 1.21 0.604 0.219 0.533 0.00339 6.9 -0.701 1.01 0.49 0.31 0.496 0.0614 3.01 PRS_PLINK_5e.04 389.1 Sensorineural hearing loss Both 7 26 7 sense organs darkseagreen4 26, 7 7, 3 6, 1 6, 1 7, 2 0.0325 0.645 0.96 0.018 1.03 0.27 3.33 -0.973 1.93 0.614 0.212 0.378 0.0104 8.3 0.919 1.94 0.637 0.196 2.51 0.0679 13500 0.936 1.95 0.632 0.2 2.55 0.0583 197 PRS_PLINK_5e.04 389.2 Conductive hearing loss Both 1 11 7 sense organs darkseagreen4 11, 1 3, 1 3, 0 2, 0 3, 0 -0.265 1.28 0.836 0.078 0.768 0.111 8.63 0.272 1400 1 0 1.31 0.31 25.7 0.301 1110 1 0 1.35 0.78 1.39 0.058 12200000 1 0 1.06 0.304 6.77 PRS_PLINK_5e.04 389.3 Degenerative and vascular disorders of ear Both 0 2 7 sense organs darkseagreen4 2, 0 1 1 1 1 PRS_PLINK_5e.04 389.4 Tinnitus Both 5 27 7 sense organs darkseagreen4 27, 5 7, 3 7, 1 6, 1 7, 0 -0.775 0.639 0.225 0.648 0.46 0.0726 1.45 -1.59 1.66 0.338 0.471 0.204 0.000625 2.59 -0.315 1.49 0.832 0.08 0.73 0.021 8.3 -1.47 1.66 0.377 0.423 0.23 0.000288 2.65 PRS_PLINK_5e.04 389.5 Disorders of acoustic nerve Both 0 1 7 sense organs darkseagreen4 1, 0 PRS_PLINK_5e.04 394 Rheumatic disease of the heart valves Both 1 8 8 circulatory system red 8, 1 2, 0 2, 0 2, 0 2, 1 -0.0619 12.6 0.996 0.002 0.94 0.23 12.7 -0.324 3830 1 0 0.723 0.51 2.18 PRS_PLINK_5e.04 394.1 Mitral valve stenosis and aortic valve stenosis Both 1 1 8 circulatory system red 1, 1 -1.03 69.7 0.988 0.005 0.358 0.336 25.2 PRS_PLINK_5e.04 394.2 Mitral valve disease Both 0 3 8 circulatory system red 3, 0 1 1 1 1 PRS_PLINK_5e.04 394.7 Disease of tricuspid valve Both 0 2 8 circulatory system red 2, 0 1 1 1 1 PRS_PLINK_5e.04 395 Heart valve disorders Both 4 31 8 circulatory system red 31, 4 8, 0 8, 2 7, 1 8, 1 0.339 0.536 0.527 0.278 1.4 0.489 4.06 1.66 1.69 0.327 0.485 5.25 0.0436 21000 0.353 2.18 0.871 0.06 1.42 0.00425 17100 0.349 1.51 0.817 0.088 1.42 0.0244 74.6 PRS_PLINK_5e.04 395.1 Nonrheumatic mitral valve disorders Both 2 18 8 circulatory system red 18, 2 5, 0 4, 0 4, 0 5, 2 0.794 0.83 0.339 0.47 2.21 0.427 21.9 0.471 1.82 0.796 0.099 1.6 0.00172 36.4 PRS_PLINK_5e.04 395.2 Nonrheumatic aortic valve disorders Both 2 14 8 circulatory system red 14, 2 4, 0 3, 2 3, 0 4, 0 -0.198 1.37 0.885 0.053 0.82 0.0426 43 0.118 219 1 0 1.13 1.68 2.67 PRS_PLINK_5e.04 395.3 Nonrheumatic tricuspid valve disorders Both 0 4 8 circulatory system red 4, 0 1 1 1 1 PRS_PLINK_5e.04 395.4 Nonrheumatic pulmonary valve disorders Both 0 2 8 circulatory system red 2, 0 1 1 1 1 PRS_PLINK_5e.04 395.6 Heart valve replaced Both 0 9 8 circulatory system red 9, 0 3 2 2 2 PRS_PLINK_5e.04 396 Abnormal heart sounds Both 4 45 8 circulatory system red 45, 4 12, 0 11, 1 11, 2 11, 1 0.159 0.481 0.74 0.13 1.17 0.421 3.59 0.192 1.45 0.895 0.048 1.21 0.0172 160 1.68 1.49 0.258 0.588 5.38 0.424 1010 0.155 1.65 0.925 0.034 1.17 0.0165 111 PRS_PLINK_5e.04 401 Hypertension Both 29 35 8 circulatory system red 35, 29 8, 4 9, 4 8, 10 9, 11 0.383 0.325 0.24 0.62 1.47 0.801 2.75 -0.514 1.15 0.654 0.184 0.598 0.0424 9.19 0.0719 1.01 0.943 0.025 1.07 0.159 8.01 0.63 1.03 0.541 0.266 1.88 0.27 18.3 PRS_PLINK_5e.04 401.1 Essential hypertension Both 29 35 8 circulatory system red 35, 29 8, 4 9, 4 8, 10 9, 11 0.383 0.325 0.24 0.62 1.47 0.801 2.75 -0.514 1.15 0.654 0.184 0.598 0.0424 9.19 0.0719 1.01 0.943 0.025 1.07 0.159 8.01 0.63 1.03 0.541 0.266 1.88 0.27 18.3 PRS_PLINK_5e.04 401.2 Hypertensive heart and/or renal disease Both 1 19 8 circulatory system red 19, 1 4, 0 5, 0 4, 0 5, 1 -0.207 0.99 0.835 0.079 0.813 0.0254 6.79 -1.54 3 0.608 0.216 0.214 0.00165 11.3 PRS_PLINK_5e.04 401.21 Hypertensive heart disease Both 0 7 8 circulatory system red 7, 0 2 2 1 2 PRS_PLINK_5e.04 401.22 Hypertensive chronic kidney disease Both 1 18 8 circulatory system red 18, 1 4, 0 4, 0 4, 0 5, 1 -0.381 0.988 0.7 0.155 0.683 0.0383 5.26 -1.54 3 0.608 0.216 0.214 0.00165 11.3 PRS_PLINK_5e.04 401.3 Other hypertensive complications Both 5 23 8 circulatory system red 23, 5 5, 1 6, 2 5, 0 6, 2 -0.581 0.807 0.472 0.326 0.559 0.0203 2.37 -0.778 1.78 0.663 0.179 0.459 0.00625 8.48 -4.6 13.8 0.739 0.131 0.0101 1.38e-12 1460000 -1.82 2.49 0.465 0.333 0.163 0.000566 5.58 PRS_PLINK_5e.04 411 Ischemic Heart Disease Both 13 34 8 circulatory system red 34, 13 9, 3 8, 2 8, 6 9, 2 0.102 0.409 0.804 0.095 1.11 0.5 2.34 -0.612 1.19 0.606 0.217 0.542 0.0512 4.52 0.123 0.982 0.9 0.046 1.13 0.201 7.17 -0.981 1.37 0.475 0.323 0.375 0.00534 3.21 PRS_PLINK_5e.04 411.1 Unstable angina (intermediate coronary syndrome) Both 0 12 8 circulatory system red 12, 0 3 3 3 3 PRS_PLINK_5e.04 411.2 Myocardial infarction Both 5 25 8 circulatory system red 25, 5 7, 1 6, 1 6, 2 6, 1 -0.268 0.713 0.707 0.15 0.765 0.0154 2.95 -0.93 1.69 0.582 0.235 0.395 0.000255 5.75 -0.348 1.79 0.846 0.073 0.706 0.0116 31.4 -0.62 2.78 0.824 0.084 0.538 0.00534 770 PRS_PLINK_5e.04 411.3 Angina pectoris Both 3 22 8 circulatory system red 22, 3 6, 1 5, 1 5, 0 6, 1 -0.0382 0.812 0.962 0.017 0.963 0.191 7.28 0.613 1.95 0.754 0.123 1.85 0.0611 2.07 -0.22 2.47 0.929 0.032 0.803 0.00241 109 -0.493 2.09 0.813 0.09 0.611 0.000275 23.6 PRS_PLINK_5e.04 411.4 Coronary atherosclerosis Both 7 31 8 circulatory system red 31, 7 8, 0 8, 2 7, 3 8, 2 0.649 0.551 0.239 0.622 1.91 0.721 10.2 0.00213 1.62 0.999 0 1 0.0467 37.2 1.35 1.6 0.397 0.402 3.87 0.28 1900 1.25 1.9 0.51 0.293 3.5 0.0223 461 PRS_PLINK_5e.04 411.41 Aneurysm and dissection of heart Both 0 3 8 circulatory system red 3, 0 1 1 1 1 PRS_PLINK_5e.04 411.8 Other chronic ischemic heart disease, unspecified Both 7 30 8 circulatory system red 30, 7 8, 1 7, 2 7, 2 8, 2 -0.178 0.517 0.73 0.136 0.837 0.3 2.13 0.0437 1.54 0.977 0.01 1.04 0.0526 33.3 -0.612 1.76 0.728 0.138 0.542 0.00174 96.4 0.632 1.45 0.664 0.178 1.88 0.104 236 PRS_PLINK_5e.04 411.9 Other acute and subacute forms of ischemic heart disease Both 0 4 8 circulatory system red 4, 0 1 1 1 1 PRS_PLINK_5e.04 414 Other forms of chronic heart disease Both 4 26 8 circulatory system red 26, 4 7, 0 6, 1 6, 1 7, 2 -0.195 0.657 0.767 0.115 0.823 0.161 2.88 -0.244 1.96 0.901 0.045 0.783 0.0132 39.5 -0.111 1.86 0.953 0.021 0.895 0.0197 51.1 -0.201 2 0.92 0.036 0.818 0.00341 349 PRS_PLINK_5e.04 414.2 ASCVD Both 1 10 8 circulatory system red 10, 1 3, 0 2, 0 2, 1 3, 0 0.0794 2.68 0.976 0.01 1.08 0.0212 136 -3.45 7910 1 0 0.0318 2.97e-09 14100 PRS_PLINK_5e.04 415 Pulmonary heart disease Both 4 33 8 circulatory system red 33, 4 9, 2 8, 1 8, 0 8, 1 -0.313 0.67 0.64 0.194 0.731 0.116 3.19 0.28 1.46 0.848 0.072 1.32 0.0856 42 -0.363 1.49 0.808 0.093 0.695 0.00201 17 -0.0352 1.49 0.981 0.008 0.965 0.00606 471 PRS_PLINK_5e.04 415.1 Acute pulmonary heart disease Both 1 19 8 circulatory system red 19, 1 5, 0 5, 1 4, 0 5, 0 0.445 1.32 0.737 0.133 1.56 0.0695 39.6 0.457 1.79 0.798 0.098 1.58 0.0935 55.1 PRS_PLINK_5e.04 415.11 Pulmonary embolism and infarction, acute Both 1 19 8 circulatory system red 19, 1 5, 0 5, 1 4, 0 5, 0 0.445 1.32 0.737 0.133 1.56 0.0695 39.6 0.457 1.79 0.798 0.098 1.58 0.0935 55.1 PRS_PLINK_5e.04 415.2 Chronic pulmonary heart disease Both 4 20 8 circulatory system red 20, 4 5, 1 5, 2 5, 0 5, 1 -0.362 0.727 0.619 0.208 0.697 0.0734 2.43 1.59 2.21 0.47 0.328 4.93 0.216 4130 0.0645 3.17 0.984 0.007 1.07 0.00163 161 0.07 2.18 0.974 0.011 1.07 0.00996 251 PRS_PLINK_5e.04 415.21 Primary pulmonary hypertension Both 3 9 8 circulatory system red 9, 3 3, 1 2, 1 2, 0 2, 1 1.07 2.29 0.639 0.194 2.93 0.117 3.11 0.339 1330 1 0 1.4 2.3 4.1 -0.000742 7010 1 0 0.999 0.191 5 -0.332 1720 1 0 0.718 0.138 4.76 PRS_PLINK_5e.04 416 Cardiomegaly Both 1 15 8 circulatory system red 15, 1 4, 0 4, 0 3, 0 4, 1 0.755 1.06 0.477 0.321 2.13 0.227 65.3 1.27 11.6 0.913 0.04 3.57 3.83 5.58 PRS_PLINK_5e.04 418 Nonspecific chest pain Both 28 35 8 circulatory system red 35, 28 8, 6 9, 11 8, 3 9, 8 0.0935 0.33 0.777 0.11 1.1 0.588 2.02 -0.0946 0.887 0.915 0.039 0.91 0.153 4.41 -1.18 1.41 0.404 0.394 0.308 0.00016 18.6 -0.08 0.922 0.931 0.031 0.923 0.178 4.7 PRS_PLINK_5e.04 418.1 Precordial pain Both 4 12 8 circulatory system red 12, 4 3, 1 3, 0 3, 0 3, 3 -0.0547 1.01 0.957 0.019 0.947 0.101 4.69 -0.141 95.1 0.999 0.001 0.868 0.18 1.26 -0.638 216 0.998 0.001 0.528 0.0214 5.48 1.08 23.8 0.964 0.016 2.94 0.894 5.34 PRS_PLINK_5e.04 420 Carditis Both 1 16 8 circulatory system red 16, 1 4, 0 4, 0 4, 0 4, 1 0.274 1.1 0.804 0.095 1.32 0.0256 23.7 0.465 3090000 1 0 1.59 0.702 8.43 PRS_PLINK_5e.04 420.2 Pericarditis Both 1 7 8 circulatory system red 7, 1 2, 0 2, 0 1, 0 2, 1 0.0294 690 1 0 1.03 1.04 1.47 -0.039 5160 1 0 0.962 0.679 1.18 PRS_PLINK_5e.04 420.21 Acute pericarditis Both 1 3 8 circulatory system red 3, 1 1, 0 1, 0 0, 1 1, 0 0.738 8920 1 0 2.09 0.113 489 -0.0127 71.8 1 0 0.987 0.848 1.17 PRS_PLINK_5e.04 420.22 Chronic pericarditis Both 1 0 8 circulatory system red 0, 1 PRS_PLINK_5e.04 420.3 Endocarditis Both 0 9 8 circulatory system red 9, 0 3 2 2 2 PRS_PLINK_5e.04 425 Cardiomyopathy Both 3 19 8 circulatory system red 19, 3 5, 0 5, 0 4, 1 5, 2 0.288 0.842 0.732 0.135 1.33 0.134 10.8 1.76e-12 19.5 1 0 1 0.121 1.05 0.756 2.76 0.784 0.106 2.13 0.0146 1740 PRS_PLINK_5e.04 425.1 Primary/intrinsic cardiomyopathies Both 3 19 8 circulatory system red 19, 3 5, 0 5, 0 4, 1 5, 2 0.288 0.842 0.732 0.135 1.33 0.134 10.8 1.76e-12 19.5 1 0 1 0.121 1.05 0.756 2.76 0.784 0.106 2.13 0.0146 1740 PRS_PLINK_5e.04 425.11 Hypertrophic obstructive cardiomyopathy Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_5e.04 425.12 Other hypertrophic cardiomyopathy Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_5e.04 425.2 Secondary/extrinsic cardiomyopathies Both 0 2 8 circulatory system red 2, 0 1 1 1 1 PRS_PLINK_5e.04 425.8 Other cardiomyopathy Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_5e.04 426 Cardiac conduction disorders Both 17 33 8 circulatory system red 33, 17 8, 5 8, 6 8, 2 8, 4 -0.118 0.364 0.745 0.128 0.889 0.435 1.71 -0.537 1.19 0.652 0.186 0.585 0.047 4.25 0.693 1.47 0.636 0.196 2 0.129 273 -1.38 1.39 0.321 0.493 0.252 0.00537 2.45 PRS_PLINK_5e.04 426.2 Atrioventricular [AV] block Both 0 12 8 circulatory system red 12, 0 3 3 3 3 PRS_PLINK_5e.04 426.21 First degree AV block Both 0 10 8 circulatory system red 10, 0 3 2 2 3 PRS_PLINK_5e.04 426.23 Second degree AV block Both 0 2 8 circulatory system red 2, 0 1 1 1 1 PRS_PLINK_5e.04 426.24 Atrioventricular block, complete Both 0 3 8 circulatory system red 3, 0 1 1 1 1 PRS_PLINK_5e.04 426.25 Other heart block Both 0 2 8 circulatory system red 2, 0 1 1 1 1 PRS_PLINK_5e.04 426.3 Bundle branch block Both 2 16 8 circulatory system red 16, 2 4, 0 4, 0 4, 0 4, 2 0.912 0.843 0.279 0.554 2.49 0.586 40 0.0829 5.87 0.989 0.005 1.09 0.000158 8320 PRS_PLINK_5e.04 426.31 Right bundle branch block Both 2 7 8 circulatory system red 7, 2 2, 0 2, 0 1, 0 2, 2 0.0442 587 1 0 1.05 0.838 1.37 0.0114 2840 1 0 1.01 0.665 1.67 PRS_PLINK_5e.04 426.32 Left bundle branch block Both 0 11 8 circulatory system red 11, 0 3 3 2 3 PRS_PLINK_5e.04 426.4 Anomalous atrioventricular excitation Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_5e.04 426.7 Abnormal electrocardiogram [ECG] [EKG] Both 16 31 8 circulatory system red 31, 16 7, 7 8, 4 7, 2 8, 3 -0.145 0.409 0.722 0.142 0.865 0.393 1.79 -1.36 1.28 0.29 0.537 0.257 0.0141 2.17 -0.962 1.67 0.564 0.249 0.382 0.00011 7.65 -1.33 1.37 0.331 0.48 0.265 0.0105 2.54 PRS_PLINK_5e.04 426.8 Other cardiac conduction disorders Both 0 5 8 circulatory system red 5, 0 2 1 1 1 PRS_PLINK_5e.04 426.9 Cardiac pacemaker/device in situ Both 1 11 8 circulatory system red 11, 1 3, 0 3, 0 2, 0 3, 1 0.741 1.74 0.67 0.174 2.1 0.159 65.1 -0.141 3180 1 0 0.868 0.854 2.15 PRS_PLINK_5e.04 426.91 Cardiac pacemaker in situ Both 0 4 8 circulatory system red 4, 0 1 1 1 1 PRS_PLINK_5e.04 426.92 Cardiac defibrillator in situ Both 0 6 8 circulatory system red 6, 0 2 1 1 2 PRS_PLINK_5e.04 427 Cardiac dysrhythmias Both 25 33 8 circulatory system red 33, 25 8, 7 8, 6 8, 2 8, 10 0.0145 0.308 0.963 0.017 1.01 0.577 1.78 -0.46 0.97 0.635 0.197 0.631 0.0923 3.46 -0.544 1.18 0.646 0.19 0.58 0.0578 5.64 -0.621 0.915 0.497 0.303 0.537 0.0747 2.53 PRS_PLINK_5e.04 427.1 Paroxysmal tachycardia, unspecified Both 4 22 8 circulatory system red 22, 4 6, 0 5, 1 5, 1 6, 2 0.866 0.778 0.266 0.575 2.38 0.599 151 0.21 3.38 0.951 0.022 1.23 0.000255 1630 1.3 2.68 0.627 0.203 3.68 0.0449 9420 -0.836 2.22 0.706 0.151 0.433 0.00119 18.7 PRS_PLINK_5e.04 427.11 Paroxysmal supraventricular tachycardia Both 2 14 8 circulatory system red 14, 2 4, 0 3, 0 3, 1 4, 1 0.578 0.881 0.512 0.291 1.78 0.434 13.3 0.235 1750 1 0 1.27 4.04 22.6 0.142 35.4 0.997 0.001 1.15 0.0158 1.24 PRS_PLINK_5e.04 427.12 Paroxysmal ventricular tachycardia Both 2 10 8 circulatory system red 10, 2 3, 0 2, 0 2, 1 3, 1 0.541 1.63 0.739 0.131 1.72 0.186 305 -2.34 14500 1 0 0.0966 1.86e-08 531000 0.0906 989 1 0 1.09 0.174 7.66 PRS_PLINK_5e.04 427.2 Atrial fibrillation and flutter Both 4 22 8 circulatory system red 22, 4 6, 2 5, 0 5, 1 6, 1 0.262 0.658 0.691 0.161 1.3 0.367 5.31 -0.475 2.3 0.837 0.077 0.622 0.00207 21.8 0.953 1.92 0.619 0.208 2.59 0.0925 429 0.0975 1.71 0.954 0.02 1.1 0.0148 29.7 PRS_PLINK_5e.04 427.21 Atrial fibrillation Both 4 20 8 circulatory system red 20, 4 5, 2 5, 0 5, 1 5, 1 0.241 0.707 0.733 0.135 1.27 0.371 5.11 -0.587 3.12 0.851 0.07 0.556 0.000565 48.2 0.865 2.14 0.686 0.164 2.37 0.0185 1660 0.334 2.58 0.897 0.047 1.4 0.000915 81.1 PRS_PLINK_5e.04 427.22 Atrial flutter Both 1 11 8 circulatory system red 11, 1 3, 1 3, 0 2, 0 3, 0 -0.415 1.42 0.77 0.113 0.661 0.071 5.39 -0.124 724 1 0 0.884 0.691 1.08 0.266 6930 1 0 1.31 0.401 1.46 0.0967 755 1 0 1.1 0.358 3.73 PRS_PLINK_5e.04 427.3 Other specified cardiac dysrhythmias Both 12 33 8 circulatory system red 33, 12 8, 3 8, 3 8, 1 8, 5 -0.0428 0.423 0.919 0.037 0.958 0.41 2.08 -2.76 2.52 0.274 0.563 0.0631 3.65e-09 3.14 0.648 1.62 0.689 0.162 1.91 0.1 23300 -0.893 1.23 0.466 0.331 0.409 0.00526 3.04 PRS_PLINK_5e.04 427.4 Cardiac arrest and ventricular fibrillation Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_5e.04 427.41 Ventricular fibrillation and flutter Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_5e.04 427.42 Cardiac arrest Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_5e.04 427.5 Arrhythmia (cardiac) NOS Both 5 32 8 circulatory system red 32, 5 7, 1 8, 2 8, 0 8, 2 0.0826 0.52 0.874 0.059 1.09 0.294 3.55 -2.14 2.15 0.32 0.494 0.118 3.78e-07 3.02 -0.917 1.63 0.573 0.242 0.4 0.000861 6.58 -1.38 1.8 0.443 0.353 0.252 0.0058 4.82 PRS_PLINK_5e.04 427.6 Premature beats Both 4 19 8 circulatory system red 19, 4 5, 2 5, 1 4, 0 5, 1 0.12 0.9 0.894 0.049 1.13 0.192 9.27 0.586 2.7 0.828 0.082 1.8 0.00426 3860 9.05 180 0.96 0.018 8530 4.65e-09 2.3e+12 -0.0509 1.6 0.975 0.011 0.95 0.853 6.18 PRS_PLINK_5e.04 427.61 Supraventricular premature beats Both 1 8 8 circulatory system red 8, 1 2, 1 2, 0 2, 0 2, 0 0.00118 34.4 1 0 1 0.361 3.24 0.044 2480 1 0 1.05 0.803 1.22 0.573 12600 1 0 1.77 0.413 4.04 0.141 672 1 0 1.15 0.775 1.6 PRS_PLINK_5e.04 427.7 Tachycardia NOS Both 5 33 8 circulatory system red 33, 5 8, 2 8, 2 8, 1 8, 0 -0.349 0.519 0.501 0.3 0.705 0.172 1.76 0.291 1.76 0.869 0.061 1.34 0.0397 23.3 0.578 1.67 0.73 0.137 1.78 0.0219 137000 -0.199 1.74 0.909 0.042 0.819 0.0329 49600 PRS_PLINK_5e.04 427.8 Sinoatrial node dysfunction (Bradycardia) Both 0 6 8 circulatory system red 6, 0 2 1 1 2 PRS_PLINK_5e.04 427.9 Palpitations Both 9 31 8 circulatory system red 31, 9 7, 3 8, 1 7, 1 8, 4 0.25 0.486 0.606 0.217 1.28 0.514 3.67 -1.85 1.7 0.276 0.559 0.158 0.00118 2.08 -0.53 1.27 0.676 0.17 0.588 0.00604 4.29 -0.00593 1.22 0.996 0.002 0.994 0.116 8.28 PRS_PLINK_5e.04 428 Congestive heart failure; nonhypertensive Both 3 20 8 circulatory system red 20, 3 4, 0 5, 1 5, 1 5, 1 0.286 0.745 0.701 0.154 1.33 0.266 43.3 0.197 190 0.999 0 1.22 0.00158 1580000 1.95 6.45 0.762 0.118 7.06 0.000833 226000 -2.26 4.7 0.63 0.201 0.104 0.0903 88.3 PRS_PLINK_5e.04 428.1 Congestive heart failure (CHF) NOS Both 2 18 8 circulatory system red 18, 2 5, 0 4, 0 4, 1 5, 1 -0.202 0.83 0.807 0.093 0.817 0.0301 12.1 2.56 6.9 0.711 0.148 12.9 0.000562 401000 -0.908 3.32 0.784 0.106 0.403 0.000163 386 PRS_PLINK_5e.04 428.2 Heart failure NOS Both 3 18 8 circulatory system red 18, 3 5, 0 4, 1 4, 1 5, 1 -0.0883 0.857 0.918 0.037 0.915 0.0553 9.88 0.00691 29 1 0 1.01 0.975 16.2 3.09 8.86 0.727 0.138 22 6.86e-05 9.16e+11 -0.361 3.04 0.905 0.043 0.697 0.00667 35200 PRS_PLINK_5e.04 428.3 Heart failure with reduced EF [Systolic or combined heart failure] Both 2 9 8 circulatory system red 9, 2 2, 0 2, 0 2, 1 2, 1 0.303 0.833 0.716 0.145 1.35 0.247 5.32 4.69 9020 1 0 108 9.84e-09 2.05e+11 -0.261 786 1 0 0.77 0.622 2.15 PRS_PLINK_5e.04 428.4 Heart failure with preserved EF [Diastolic heart failure] Both 1 11 8 circulatory system red 11, 1 3, 0 3, 0 2, 0 3, 1 -0.491 4.39 0.911 0.041 0.612 0.00133 589 -0.167 1350 1 0 0.846 0.301 2.19 PRS_PLINK_5e.04 429 Ill-defined descriptions and complications of heart disease Both 28 35 8 circulatory system red 35, 28 8, 8 9, 9 8, 2 9, 9 -0.0735 0.31 0.813 0.09 0.929 0.513 1.64 -0.662 0.844 0.433 0.364 0.516 0.0999 2.14 -0.781 1.27 0.54 0.268 0.458 0.0308 22.8 -1.27 1.02 0.215 0.667 0.282 0.0288 1.56 PRS_PLINK_5e.04 429.1 Heart transplant/surgery Both 2 5 8 circulatory system red 5, 2 2, 0 1, 0 1, 1 1, 1 0.403 5010 1 0 1.5 0.237 142 -0.138 25100 1 0 0.871 0.778 82.3 -0.00477 33.1 1 0 0.995 0.746 1.09 PRS_PLINK_5e.04 429.2 Abnormal function study of cardiovascular system Both 15 30 8 circulatory system red 30, 15 7, 6 7, 4 7, 1 8, 4 -0.267 0.47 0.569 0.245 0.766 0.304 1.77 -1.47 1.37 0.284 0.547 0.231 0.00841 1.97 -2.56 2.1 0.223 0.652 0.0773 4.75e-06 1.72 -2.05 1.55 0.184 0.734 0.128 0.000451 1.4 PRS_PLINK_5e.04 429.3 Symptoms involving cardiovascular system Both 18 35 8 circulatory system red 35, 18 8, 4 9, 6 8, 2 9, 6 0.0253 0.381 0.947 0.024 1.03 0.497 2.15 -1.01 1.13 0.372 0.429 0.365 0.0194 2.38 -0.685 1.29 0.596 0.225 0.504 0.0293 24.4 -0.705 1.22 0.562 0.25 0.494 0.0478 4.03 PRS_PLINK_5e.04 429.9 Cardiac complications, not elsewhere classified Both 1 2 8 circulatory system red 2, 1 1, 0 0, 1 1, 0 1, 0 0.00211 21.6 1 0 1 0.937 1.03 -0.00123 123 1 0 0.999 0.978 4.12 PRS_PLINK_5e.04 430 Intracranial hemorrhage Both 1 11 8 circulatory system red 11, 1 3, 1 3, 0 2, 0 3, 0 0.372 2.53 0.883 0.054 1.45 0.012 1160 0.0417 94.8 1 0 1.04 0.958 1.14 0.967 559 0.999 0.001 2.63 1.37 10.4 -0.108 645 1 0 0.898 0.449 1.36 PRS_PLINK_5e.04 430.1 Subarachnoid hemorrhage Both 0 4 8 circulatory system red 4, 0 1 1 1 1 PRS_PLINK_5e.04 430.2 Intracerebral hemorrhage Both 0 3 8 circulatory system red 3, 0 1 1 1 1 PRS_PLINK_5e.04 430.3 Subdural hemorrhage Both 0 3 8 circulatory system red 3, 0 1 1 1 1 PRS_PLINK_5e.04 433 Cerebrovascular disease Both 8 35 8 circulatory system red 35, 8 9, 4 9, 2 8, 0 9, 2 -0.724 0.557 0.194 0.712 0.485 0.129 1.33 -0.87 1.2 0.47 0.328 0.419 0.0412 3.44 -1.85 1.65 0.262 0.582 0.158 0.000694 2.04 -2.24 1.93 0.246 0.609 0.107 8.91e-07 2.61 PRS_PLINK_5e.04 433.1 Occlusion and stenosis of precerebral arteries Both 3 15 8 circulatory system red 15, 3 4, 2 4, 0 3, 0 4, 1 -0.301 1.3 0.817 0.088 0.74 5.01e-05 7.31 0.0312 396 1 0 1.03 0.922 1.55 1.54 264 0.995 0.002 4.67 20.8 23.1 1.41 5.26 0.789 0.103 4.1 3.66 4.54 PRS_PLINK_5e.04 433.11 Occlusion of cerebral arteries, with cerebral infarction Both 1 2 8 circulatory system red 2, 1 1, 0 1, 1 1, 0 1, 1 0.0891 227 1 0 1.09 0.00861 1.78 0.0051 33.1 1 0 1.01 0.936 1.06 PRS_PLINK_5e.04 433.12 Cerebral atherosclerosis Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_5e.04 433.2 Occlusion of cerebral arteries Both 2 24 8 circulatory system red 24, 2 6, 0 6, 0 6, 1 6, 1 0.16 0.76 0.833 0.079 1.17 0.108 16.8 0.108 1.92 0.955 0.02 1.11 0.021 80.2 0.305 2.2 0.89 0.051 1.36 0.0487 164 PRS_PLINK_5e.04 433.21 Cerebral artery occlusion, with cerebral infarction Both 2 23 8 circulatory system red 23, 2 6, 0 6, 1 5, 0 6, 1 0.153 0.76 0.84 0.076 1.17 0.119 17.5 -0.0716 2.13 0.973 0.012 0.931 0.0141 331 0.306 2.24 0.892 0.05 1.36 0.0462 95.7 PRS_PLINK_5e.04 433.3 Cerebral ischemia Both 5 25 8 circulatory system red 25, 5 7, 2 6, 0 6, 1 6, 2 -0.418 0.736 0.571 0.244 0.659 0.0171 2.86 -0.347 1.85 0.851 0.07 0.707 0.000618 359 -0.53 1.69 0.754 0.123 0.589 0.0225 10.8 -0.672 1.58 0.671 0.173 0.511 0.000304 6.62 PRS_PLINK_5e.04 433.31 Transient cerebral ischemia Both 4 21 8 circulatory system red 21, 4 6, 1 5, 0 5, 1 5, 2 -0.352 0.902 0.696 0.157 0.703 0.00751 3.95 -0.621 2.15 0.773 0.112 0.537 0.0102 30 -0.574 1.94 0.767 0.115 0.563 0.000367 10.7 0.364 2.29 0.874 0.059 1.44 0.000206 945 PRS_PLINK_5e.04 433.5 Cerebral aneurysm Both 1 8 8 circulatory system red 8, 1 2, 0 2, 1 2, 0 2, 0 -0.0338 48.7 0.999 0 0.967 0.0129 0.94 0.0282 1040 1 0 1.03 0.652 2.47 PRS_PLINK_5e.04 433.6 Acute, but ill-defined cerebrovascular disease Both 0 6 8 circulatory system red 6, 0 2 1 1 2 PRS_PLINK_5e.04 433.8 Late effects of cerebrovascular disease Both 1 7 8 circulatory system red 7, 1 2, 0 2, 0 1, 0 2, 1 0.536 3080000 1 0 1.71 0.261 6.42 0.136 3990 1 0 1.15 0.644 3.71 PRS_PLINK_5e.04 440 Atherosclerosis Both 2 19 8 circulatory system red 19, 2 5, 0 5, 2 4, 0 5, 0 -0.319 1 0.751 0.125 0.727 0.057 1310 2.13 2.49 0.393 0.406 8.4 0.279 3410000 PRS_PLINK_5e.04 440.1 Atherosclerosis of renal artery Both 0 2 8 circulatory system red 2, 0 1 1 1 1 PRS_PLINK_5e.04 440.2 Atherosclerosis of the extremities Both 2 16 8 circulatory system red 16, 2 4, 1 4, 1 4, 0 4, 0 -0.332 1.26 0.792 0.101 0.717 0.0486 259 1.59 3.03 0.6 0.222 4.89 0.105 2030 2.88 304 0.992 0.003 17.7 10.8 108000 -0.374 36.7 0.992 0.004 0.688 1.24e-05 24300 PRS_PLINK_5e.04 440.21 Atherosclerosis of native arteries of the extremities with ulceration or gangrene Both 0 9 8 circulatory system red 9, 0 3 2 2 2 PRS_PLINK_5e.04 440.22 Atherosclerosis of native arteries of the extremities with intermittent claudication Both 2 11 8 circulatory system red 11, 2 3, 0 3, 2 2, 0 3, 0 0.0451 1.69 0.979 0.009 1.05 0.0639 1.18 0.702 16 0.965 0.015 2.02 3.84 3.73 PRS_PLINK_5e.04 440.9 Atherosclerosis of aorta Both 1 3 8 circulatory system red 3, 1 1, 0 1, 0 0, 1 1, 0 0.391 2650 1 0 1.48 0.465 1.68 -0.00191 675 1 0 0.998 0.973 1.03 PRS_PLINK_5e.04 441 Vascular insufficiency of intestine Both 0 8 8 circulatory system red 8, 0 2 2 2 2 PRS_PLINK_5e.04 441.1 Acute vascular insufficiency of intestine Both 0 3 8 circulatory system red 3, 0 1 1 1 1 PRS_PLINK_5e.04 442 Other aneurysm Both 4 21 8 circulatory system red 21, 4 6, 1 5, 2 5, 1 5, 0 0.328 0.953 0.731 0.136 1.39 0.132 1.55 0.654 2.01 0.745 0.128 1.92 0.0764 721 0.391 2.1 0.852 0.069 1.48 0.011 59 1.36 10.8 0.9 0.046 3.91 3.38 4.44 PRS_PLINK_5e.04 442.1 Aortic aneurysm Both 3 13 8 circulatory system red 13, 3 4, 1 3, 1 3, 1 3, 0 0.313 1.42 0.826 0.083 1.37 0.0701 26.2 -1.53 17.2 0.929 0.032 0.217 3.01e-06 6690 -7.14 79.6 0.929 0.032 0.000789 0.000536 0.00114 -2.32 2510 0.999 0 0.0988 0.0345 0.208 PRS_PLINK_5e.04 442.11 Abdominal aortic aneurysm Both 1 4 8 circulatory system red 4, 1 1, 0 1, 1 1, 0 1, 0 0.193 3360 1 0 1.21 0.27 1.33 0.00496 38.7 1 0 1 0.663 1.3 PRS_PLINK_5e.04 442.3 Aneurysm of artery of lower extremity Both 0 2 8 circulatory system red 2, 0 1 1 1 1 PRS_PLINK_5e.04 442.4 Arterial dissection Both 1 0 8 circulatory system red 0, 1 PRS_PLINK_5e.04 442.8 Aneurysm of other specified artery Both 0 3 8 circulatory system red 3, 0 1 1 1 1 PRS_PLINK_5e.04 443 Peripheral vascular disease Both 3 28 8 circulatory system red 28, 3 7, 0 7, 1 7, 0 7, 2 0.878 0.885 0.321 0.494 2.41 0.459 552 0.959 1.99 0.629 0.201 2.61 0.00656 2410 2.61 2.86 0.361 0.442 13.6 0.18 1480000 PRS_PLINK_5e.04 443.1 Raynaud's syndrome Both 1 7 8 circulatory system red 7, 1 2, 0 2, 0 1, 0 2, 1 0.0284 313 1 0 1.03 0.418 3.28 -0.0251 2270 1 0 0.975 0.335 1.71 PRS_PLINK_5e.04 443.7 Peripheral angiopathy in diseases classified elsewhere Both 1 5 8 circulatory system red 5, 1 2, 0 1, 0 1, 1 1, 0 0.155 3290 1 0 1.17 0.276 6.05 -0.172 28400 1 0 0.842 0.0727 5.81 PRS_PLINK_5e.04 443.8 Other specified peripheral vascular diseases Both 3 27 8 circulatory system red 27, 3 7, 0 7, 1 6, 0 7, 2 0.886 0.892 0.32 0.494 2.43 0.461 587 1.19 1.98 0.548 0.261 3.29 0.0349 537 3.06 2.85 0.283 0.548 21.3 0.263 656000 PRS_PLINK_5e.04 443.9 Peripheral vascular disease, unspecified Both 3 23 8 circulatory system red 23, 3 6, 0 6, 1 5, 0 6, 2 0.645 0.784 0.411 0.387 1.91 0.381 24.1 1.09 2 0.587 0.232 2.96 0.0407 3250 1.56 2.48 0.527 0.278 4.78 0.0882 355 PRS_PLINK_5e.04 444 Arterial embolism and thrombosis Both 1 13 8 circulatory system red 13, 1 4, 0 3, 1 3, 0 3, 0 0.111 2.36 0.962 0.017 1.12 0.00258 81.1 0.208 6810 1 0 1.23 1.11 6.81 PRS_PLINK_5e.04 444.1 Arterial embolism and thrombosis of lower extremity artery Both 0 4 8 circulatory system red 4, 0 1 1 1 1 PRS_PLINK_5e.04 444.2 Embolism and thrombosis of abdominal aorta Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_5e.04 446 Polyarteritis nodosa and allied conditions Both 1 10 8 circulatory system red 10, 1 3, 0 2, 1 2, 0 3, 0 -0.373 4.13 0.928 0.032 0.688 0.000814 804 -0.0956 579 1 0 0.909 0.0872 5.85 PRS_PLINK_5e.04 446.4 Wegener's granulomatosis Both 0 3 8 circulatory system red 3, 0 1 1 1 1 PRS_PLINK_5e.04 446.5 Giant cell arteritis Both 1 1 8 circulatory system red 1, 1 0.0397 43.2 0.999 0 1.04 0.941 1.06 PRS_PLINK_5e.04 446.9 Arteritis NOS Both 1 4 8 circulatory system red 4, 1 1, 0 1, 1 1, 0 1, 0 0.397 3910 1 0 1.49 0.491 3.67 2.23 3060 0.999 0 9.34 1.92e-07 219000 PRS_PLINK_5e.04 447 Other disorders of arteries and arterioles Both 3 23 8 circulatory system red 23, 3 5, 1 6, 2 5, 0 6, 0 0.0144 0.685 0.983 0.007 1.01 0.207 5.57 1.51 2.05 0.462 0.336 4.53 0.204 35300 -1.65 10.8 0.878 0.056 0.192 0.00087 48.9 -0.563 2.77 0.839 0.076 0.569 0.00462 47.3 PRS_PLINK_5e.04 447.1 Stricture of artery Both 1 5 8 circulatory system red 5, 1 2, 0 1, 0 1, 0 1, 1 -0.284 7590 1 0 0.752 0.959 1.68 -0.172 28400 1 0 0.842 0.0727 5.81 PRS_PLINK_5e.04 447.7 Aortic ectasia Both 0 11 8 circulatory system red 11, 0 2 3 2 3 PRS_PLINK_5e.04 448 Disease of capillaries Both 1 13 8 circulatory system red 13, 1 4, 0 3, 1 3, 0 3, 0 -0.122 1.17 0.917 0.038 0.886 0.0521 5.55 1.17 132 0.993 0.003 3.22 0.00642 2300 PRS_PLINK_5e.04 450 Noninfectious disorders of lymphatic channels Both 1 22 8 circulatory system red 22, 1 6, 0 5, 0 5, 1 6, 0 0.00251 0.784 0.997 0.001 1 0.0963 5.84 1.66 22.1 0.94 0.027 5.27 1.89e-09 1.59e+11 PRS_PLINK_5e.04 451 Phlebitis and thrombophlebitis Both 3 6 8 circulatory system red 6, 3 2, 3 1, 0 1, 0 2, 0 0.0799 1690 1 0 1.08 0.782 1.93 -0.0699 1570 1 0 0.932 0.222 2.98 -0.283 11900000 1 0 0.753 0.398 2.85 0.0588 6550 1 0 1.06 0.033 283 PRS_PLINK_5e.04 451.2 Phlebitis and thrombophlebitis of lower extremities Both 2 2 8 circulatory system red 2, 2 1, 2 1, 0 1, 2 1, 0 0.106 2890 1 0 1.11 0.634 3.68 0.517 6770 1 0 1.68 0.375 55.8 PRS_PLINK_5e.04 452 Other venous embolism and thrombosis Both 5 30 8 circulatory system red 30, 5 8, 1 7, 2 7, 0 8, 2 -0.0463 0.534 0.931 0.031 0.955 0.295 2.8 -0.975 1.59 0.54 0.267 0.377 0.00907 19.4 -0.929 1.92 0.628 0.202 0.395 0.000257 13.4 -0.177 1.45 0.902 0.045 0.838 0.00101 14.2 PRS_PLINK_5e.04 452.1 Iatrogenic pulmonary embolism and infarction Both 0 6 8 circulatory system red 6, 0 2 1 1 2 PRS_PLINK_5e.04 452.2 Deep vein thrombosis [DVT] Both 4 23 8 circulatory system red 23, 4 6, 1 6, 2 5, 0 6, 1 -0.145 0.71 0.838 0.077 0.865 0.0757 3.39 -0.639 1.97 0.746 0.127 0.528 0.00733 22.7 -0.486 2.39 0.839 0.076 0.615 0.00192 54.6 -0.651 2.78 0.815 0.089 0.522 0.000245 106 PRS_PLINK_5e.04 452.8 Postphlebitic syndrome Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_5e.04 453 Chronic venous hypertension Both 0 3 8 circulatory system red 3, 0 1 1 1 1 PRS_PLINK_5e.04 454 Varicose veins Both 5 23 8 circulatory system red 23, 5 5, 0 6, 3 5, 1 6, 1 0.233 0.945 0.805 0.094 1.26 0.0529 69.1 0.907 3.32 0.785 0.105 2.48 0.00204 92000 1.48 3.19 0.643 0.192 4.38 0.0462 1880 1.54 3.85 0.69 0.161 4.64 0.0197 1950 PRS_PLINK_5e.04 454.1 Varicose veins of lower extremity Both 4 19 8 circulatory system red 19, 4 5, 1 5, 1 4, 1 5, 1 -0.307 1.02 0.763 0.118 0.736 0.0129 9.55 1.06 3.08 0.731 0.136 2.88 0.0146 919 6.4 16.8 0.703 0.153 602 3.59e-10 7.74e+17 2.07 14.1 0.883 0.054 7.91 6.96e-11 3.98e+13 PRS_PLINK_5e.04 454.11 Varicose veins of lower extremity, symptomtic Both 4 15 8 circulatory system red 15, 4 4, 1 4, 1 3, 1 4, 1 -0.292 1.02 0.774 0.111 0.746 0.0154 5.57 0.126 1160 1 0 1.13 0.836 1.2 7.31 20.5 0.721 0.142 1490 3.23e-09 2290 0.0348 107 1 0 1.04 0.853 0.99 PRS_PLINK_5e.04 455 Hemorrhoids Both 16 28 8 circulatory system red 28, 16 7, 3 7, 5 7, 4 7, 4 0.0567 0.452 0.9 0.046 1.06 0.458 2.76 -0.127 1.23 0.918 0.037 0.881 0.0723 10.1 0.288 1.33 0.829 0.082 1.33 0.117 47.6 -0.0529 1.29 0.967 0.014 0.948 0.0835 9.54 PRS_PLINK_5e.04 456 Chronic venous insufficiency [CVI] Both 8 24 8 circulatory system red 24, 8 6, 0 6, 3 6, 3 6, 2 0.466 1.11 0.676 0.17 1.59 0.0181 2630 0.847 1.97 0.667 0.176 2.33 0.0785 137 1.55 2.01 0.441 0.356 4.69 0.0273 2020 -1.35 3.43 0.694 0.159 0.259 4.72e-05 4430 PRS_PLINK_5e.04 457 Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin Both 1 12 8 circulatory system red 12, 1 3, 0 3, 0 3, 0 3, 1 0.293 0.946 0.757 0.121 1.34 0.195 18.6 0.103 665 1 0 1.11 0.317 2.87 PRS_PLINK_5e.04 457.2 Encounter for long-term (current) use of antiplatelets/antithrombotics Both 0 2 8 circulatory system red 2, 0 1 1 1 1 PRS_PLINK_5e.04 457.3 Encounter for long-term (current) use of aspirin Both 1 11 8 circulatory system red 11, 1 3, 0 3, 0 2, 0 3, 1 0.0693 1.19 0.953 0.021 1.07 0.0636 17.4 -0.14 5730000 1 0 0.869 0.383 3.94 PRS_PLINK_5e.04 458 Hypotension Both 3 38 8 circulatory system red 38, 3 10, 1 9, 0 9, 1 10, 1 0.404 0.631 0.522 0.283 1.5 0.294 6.94 -0.92 1.77 0.602 0.22 0.399 1.98e-05 14.3 0.496 1.45 0.733 0.135 1.64 0.0423 172 0.402 1.35 0.765 0.116 1.49 0.0627 26.2 PRS_PLINK_5e.04 458.1 Orthostatic hypotension Both 0 19 8 circulatory system red 19, 0 5 5 4 5 PRS_PLINK_5e.04 458.2 Iatrogenic hypotension Both 0 12 8 circulatory system red 12, 0 3 3 3 3 PRS_PLINK_5e.04 458.9 Hypotension NOS Both 3 35 8 circulatory system red 35, 3 9, 1 9, 0 8, 2 9, 0 0.334 0.643 0.604 0.219 1.4 0.248 6.59 -1.25 1.85 0.498 0.303 0.286 9.37e-05 10.6 0.278 1.42 0.845 0.073 1.32 0.00367 81.1 -0.578 1.55 0.709 0.149 0.561 0.000967 14 PRS_PLINK_5e.04 459 Other disorders of circulatory system Both 9 49 8 circulatory system red 49, 9 13, 2 12, 0 12, 3 12, 4 -0.0968 0.441 0.826 0.083 0.908 0.347 2.16 -0.862 1.23 0.484 0.315 0.422 0.0049 4.17 0.129 1.2 0.914 0.039 1.14 0.0932 14 -0.0711 1.06 0.946 0.024 0.931 0.0788 6.89 PRS_PLINK_5e.04 459.1 Hemorrhage NOS Both 0 11 8 circulatory system red 11, 0 3 3 2 3 PRS_PLINK_5e.04 459.7 Blood vessel replaced Both 1 12 8 circulatory system red 12, 1 3, 1 3, 0 3, 0 3, 0 0.478 1.92 0.804 0.095 1.61 0.00229 91.1 0.81 1330 1 0 2.25 0.436 2.41 0.00791 169 1 0 1.01 0.00992 60.6 -2.05 2950 0.999 0 0.129 1.48e-08 992000 PRS_PLINK_5e.04 459.9 Circulatory disease NEC Both 9 46 8 circulatory system red 46, 9 12, 2 11, 0 11, 3 12, 4 -0.0589 0.461 0.898 0.047 0.943 0.35 2.31 -0.85 1.4 0.543 0.266 0.428 0.00799 7.5 -0.261 1.16 0.822 0.085 0.77 0.0678 8.57 -1.02 1.35 0.447 0.35 0.359 0.00567 4.62 PRS_PLINK_5e.04 464 Acute sinusitis Both 11 34 9 respiratory coral4 34, 11 8, 2 8, 2 8, 3 9, 4 0.487 0.424 0.25 0.602 1.63 0.749 3.86 0.298 1.56 0.848 0.071 1.35 0.00081 40 0.624 1.69 0.711 0.148 1.87 0.109 57.8 0.708 1.37 0.606 0.218 2.03 0.159 57.1 PRS_PLINK_5e.04 465 Acute upper respiratory infections of multiple or unspecified sites Both 24 36 9 respiratory coral4 36, 24 8, 1 9, 5 9, 12 9, 6 0.411 0.309 0.183 0.737 1.51 0.87 2.69 1.05 1.11 0.342 0.466 2.86 0.453 32.7 1.82 1.12 0.104 0.984 6.19 1.01 76.5 1.2 1.48 0.42 0.377 3.31 0.2 3830 PRS_PLINK_5e.04 465.2 Acute pharyngitis Both 17 37 9 respiratory coral4 37, 17 9, 0 9, 4 9, 9 9, 4 0.5 0.326 0.125 0.903 1.65 0.93 3.06 1.49 1.27 0.24 0.619 4.45 0.588 1180 3.61 1.71 0.0354 1.451 36.8 2.56 9880 1.82 1.46 0.214 0.67 6.16 0.583 242 PRS_PLINK_5e.04 465.4 Acute laryngitis and tracheitis Both 0 3 9 respiratory coral4 3, 0 1 1 1 1 PRS_PLINK_5e.04 470 Septal Deviations/Turbinate Hypertrophy Both 2 22 9 respiratory coral4 22, 2 5, 0 5, 2 5, 0 6, 0 -0.603 0.713 0.398 0.4 0.547 0.00885 2.13 1.8 2.43 0.458 0.339 6.06 0.103 439 PRS_PLINK_5e.04 471 Nasal polyps Both 2 5 9 respiratory coral4 5, 2 2, 2 1, 0 1, 0 1, 0 0.0372 45.7 0.999 0 1.04 0.905 1.25 -1.54e-05 16200 1 0 1 0.0262 34.7 1.94e-05 11400 1 0 1 0.68 39.5 4.82e-05 5250 1 0 1 0.154 7.02 PRS_PLINK_5e.04 472 Chronic pharyngitis and nasopharyngitis Both 5 23 9 respiratory coral4 23, 5 5, 2 6, 2 5, 0 6, 1 -0.145 0.693 0.834 0.079 0.865 0.126 3.49 2.71 2.92 0.354 0.45 15 0.224 6630 1.28 6.57 0.845 0.073 3.61 3.27 3.96 -0.135 2.07 0.948 0.023 0.874 0.0322 25.7 PRS_PLINK_5e.04 473 Diseases of the larynx and vocal cords Both 5 26 9 respiratory coral4 26, 5 7, 0 6, 1 6, 1 7, 3 -0.0249 0.727 0.973 0.012 0.975 0.157 40.7 0.93 1.83 0.612 0.213 2.54 0.13 104 -0.0416 2.41 0.986 0.006 0.959 0.00679 269 0.113 1.73 0.948 0.023 1.12 0.0103 66.7 PRS_PLINK_5e.04 473.1 Chronic laryngitis Both 0 1 9 respiratory coral4 1, 0 PRS_PLINK_5e.04 473.3 Paralysis/spasm of vocal cords or larynx Both 1 4 9 respiratory coral4 4, 1 1, 0 1, 0 1, 0 1, 1 -1.33 3.87e+08 1 0 0.265 2.13e-12 7.31e+12 -0.0167 41 1 0 0.983 0.934 1.02 PRS_PLINK_5e.04 473.4 Voice disturbance Both 3 19 9 respiratory coral4 19, 3 5, 0 5, 1 4, 0 5, 2 0.271 0.928 0.771 0.113 1.31 0.139 21.6 1.45 2.13 0.498 0.302 4.24 0.221 426 0.448 6.3 0.943 0.025 1.57 4.92e-07 495000 PRS_PLINK_5e.04 474 Acute and chronic tonsillitis Both 3 13 9 respiratory coral4 13, 3 4, 0 3, 0 3, 0 3, 3 -0.207 1.22 0.865 0.063 0.813 0.0276 6.2 5.42 14 0.698 0.156 226 2.31e-06 362 PRS_PLINK_5e.04 474.1 Acute tonsillitis Both 1 8 9 respiratory coral4 8, 1 2, 0 2, 0 2, 1 2, 0 0.0991 74.9 0.999 0 1.1 0.197 1.12 0.0255 884 1 0 1.03 0.16 8.04 PRS_PLINK_5e.04 474.2 Chronic tonsillitis and adenoiditis Both 3 8 9 respiratory coral4 8, 3 2, 0 2, 0 2, 1 2, 2 -1.01 3.2 0.752 0.124 0.364 0.0193 26.4 2.26 1.5e+08 1 0 9.56 8.4e-14 1.05e+18 0.392 1350 1 0 1.48 0.635 1.66 PRS_PLINK_5e.04 475 Chronic sinusitis Both 11 31 9 respiratory coral4 31, 11 8, 4 8, 2 7, 2 8, 3 -0.0891 0.451 0.843 0.074 0.915 0.375 2.05 -1.57 1.56 0.313 0.504 0.207 0.00559 2.55 0.216 1.99 0.914 0.039 1.24 0.00369 19900 -1.91 1.83 0.296 0.528 0.148 0.000334 20.2 PRS_PLINK_5e.04 475.9 Postnasal drip Both 4 7 9 respiratory coral4 7, 4 2, 1 2, 0 1, 0 2, 3 0.881 2.42 0.716 0.145 2.41 0.0804 2.86 -1.59 6600 1 0 0.205 0.000752 24.3 -6.03 13000 1 0 0.0024 3.73e-05 7270 -0.303 8120000 1 0 0.738 0.0104 48.3 PRS_PLINK_5e.04 476 Allergic rhinitis Both 24 32 9 respiratory coral4 32, 24 7, 6 8, 8 8, 3 8, 7 0.0392 0.322 0.903 0.044 1.04 0.565 1.88 0.185 0.952 0.846 0.073 1.2 0.219 6.6 0.0275 1.11 0.98 0.009 1.03 0.148 9.55 -1.42 1.39 0.309 0.51 0.242 0.00711 2.73 PRS_PLINK_5e.04 477 Epistaxis or throat hemorrhage Both 1 11 9 respiratory coral4 11, 1 3, 1 3, 0 2, 0 3, 0 -0.87 2.22 0.695 0.158 0.419 0.372 9 -0.277 3050 1 0 0.758 0.75 1.33 0.16 1860 1 0 1.17 3.62e-05 2.03 -0.304 96.3 0.997 0.001 0.738 0.183 0.596 PRS_PLINK_5e.04 478 Throat pain Both 1 5 9 respiratory coral4 5, 1 2, 0 1, 1 1, 0 1, 0 1.74 940 0.999 0.001 5.71 0.000317 9940000 -0.0188 18.8 0.999 0 0.981 0.959 1.06 PRS_PLINK_5e.04 479 Other upper respiratory disease Both 11 32 9 respiratory coral4 32, 11 7, 3 8, 6 8, 0 8, 2 -0.267 0.428 0.534 0.273 0.766 0.328 1.64 0.46 1.37 0.738 0.132 1.58 0.148 37.6 -0.0877 2.1 0.967 0.015 0.916 0.00517 2180 -0.549 1.67 0.743 0.129 0.578 0.00947 22.6 PRS_PLINK_5e.04 480 Pneumonia Both 13 43 9 respiratory coral4 43, 13 11, 4 11, 2 10, 1 11, 5 -0.348 0.405 0.39 0.409 0.706 0.296 1.47 -0.605 1.34 0.652 0.186 0.546 0.00744 6.97 -0.187 1.19 0.874 0.058 0.829 0.075 10.4 -0.731 1.22 0.549 0.261 0.481 0.00266 6.46 PRS_PLINK_5e.04 480.1 Bacterial pneumonia Both 5 13 9 respiratory coral4 13, 5 4, 3 3, 0 3, 1 3, 1 -0.867 1.11 0.433 0.363 0.42 0.368 2.22 -0.121 8.15 0.988 0.005 0.886 3.43e-08 36700000 1.35 5.5 0.805 0.094 3.87 3.35 4.39 -0.897 8.57 0.917 0.038 0.408 1.88e-08 36500000 PRS_PLINK_5e.04 480.11 Pneumococcal pneumonia Both 3 5 9 respiratory coral4 5, 3 2, 1 1, 0 1, 1 1, 1 0.985 1140000 1 0 2.68 0.872 6.88 0.599 17600 1 0 1.82 0.237 3.85 0.0599 3600 1 0 1.06 0.775 1.81 0.285 955 1 0 1.33 0.527 1.74 PRS_PLINK_5e.04 480.12 Pseudomonal pneumonia Both 1 2 9 respiratory coral4 2, 1 1, 0 0, 1 1, 0 1, 0 -0.0381 254 1 0 0.963 0.644 1.24 -0.00495 35.7 1 0 0.995 0.903 6.6 PRS_PLINK_5e.04 480.2 Viral pneumonia Both 1 7 9 respiratory coral4 7, 1 2, 0 2, 0 1, 0 2, 1 -0.00799 60.7 1 0 0.992 0.846 1.34 -0.00149 439 1 0 0.999 0.0519 10.4 PRS_PLINK_5e.04 480.3 Pneumonia due to fungus (mycoses) Both 2 3 9 respiratory coral4 3, 2 1, 0 1, 2 1, 0 1, 0 0.298 10700000 1 0 1.35 0.121 16.2 0.417 2510 1 0 1.52 0.404 2.36 PRS_PLINK_5e.04 480.5 Bronchopneumonia and lung abscess Both 0 1 9 respiratory coral4 1, 0 PRS_PLINK_5e.04 481 Influenza Both 4 22 9 respiratory coral4 22, 4 6, 1 5, 1 5, 1 6, 1 -0.157 0.785 0.842 0.075 0.855 0.128 4.28 0.0155 2.35 0.995 0.002 1.02 0.00364 667 -0.662 1.74 0.704 0.152 0.516 0.0133 9.5 0.271 1.83 0.883 0.054 1.31 0.0508 115 PRS_PLINK_5e.04 483 Acute bronchitis and bronchiolitis Both 9 35 9 respiratory coral4 35, 9 9, 2 9, 2 8, 2 9, 3 0.134 0.406 0.742 0.13 1.14 0.512 2.41 -0.425 1.23 0.729 0.137 0.654 0.0706 5.76 0.555 1.24 0.655 0.184 1.74 0.191 18.8 -0.0634 1.54 0.967 0.014 0.939 0.00344 25.2 PRS_PLINK_5e.04 495 Asthma Both 15 45 9 respiratory coral4 45, 15 11, 3 11, 5 11, 2 11, 5 0.22 0.365 0.546 0.263 1.25 0.61 2.53 -0.87 1.24 0.484 0.315 0.419 0.0309 3.77 -0.162 1.02 0.874 0.059 0.85 0.131 7.52 -0.144 1.08 0.894 0.049 0.866 0.0996 6.19 PRS_PLINK_5e.04 495.1 Chronic obstructive asthma Both 1 3 9 respiratory coral4 3, 1 1, 1 1, 0 1, 0 1, 1 -0.116 6760 1 0 0.891 0.277 1.73 0.0148 71 1 0 1.01 0.882 1.22 -0.0155 70.1 1 0 0.985 0.898 1.88 PRS_PLINK_5e.04 495.11 Chronic obstructive asthma with exacerbation Both 1 3 9 respiratory coral4 3, 1 1, 1 1, 0 1, 0 1, 1 -0.0317 7790 1 0 0.969 0.0638 3.02 -0.187 5750 1 0 0.829 0.103 1.71 0.00503 33.1 1 0 1.01 0.973 1.04 PRS_PLINK_5e.04 495.2 Asthma with exacerbation Both 7 26 9 respiratory coral4 26, 7 6, 0 6, 4 6, 1 7, 2 0.152 0.474 0.749 0.125 1.16 0.428 2.91 3.32 3.45 0.336 0.474 27.6 0.209 3.45e+10 0.718 2.39 0.764 0.117 2.05 0.00757 553 -0.543 4.64 0.907 0.042 0.581 6.3e-05 382000 PRS_PLINK_5e.04 496 Chronic airway obstruction Both 7 31 9 respiratory coral4 31, 7 8, 3 8, 2 7, 1 8, 1 0.113 0.588 0.848 0.072 1.12 0.33 4.05 -1.69 1.58 0.284 0.546 0.184 0.00599 2.34 0.224 1.67 0.893 0.049 1.25 0.0081 21500 -1.1 1.68 0.514 0.289 0.334 0.0024 17.6 PRS_PLINK_5e.04 496.1 Emphysema Both 1 12 9 respiratory coral4 12, 1 3, 0 3, 0 3, 0 3, 1 0.649 1.57 0.679 0.168 1.91 0.045 48.6 0.319 722 1 0 1.38 0.113 12.9 PRS_PLINK_5e.04 496.2 Chronic bronchitis Both 3 22 9 respiratory coral4 22, 3 6, 1 5, 1 5, 1 6, 0 -0.11 0.834 0.895 0.048 0.896 0.0216 8.15 0.407 4.28 0.924 0.034 1.5 0.000546 1690 0.287 2.06 0.889 0.051 1.33 0.0171 975 0.0558 1.86 0.976 0.011 1.06 0.0257 30.9 PRS_PLINK_5e.04 496.21 Obstructive chronic bronchitis Both 2 20 9 respiratory coral4 20, 2 5, 1 5, 0 5, 1 5, 0 -0.135 0.825 0.87 0.06 0.874 0.0993 5.83 1.57 5.71 0.783 0.106 4.83 0.000752 20500 -0.243 1.77 0.891 0.05 0.784 0.0211 14.9 0.526 5.11 0.918 0.037 1.69 2.76e-05 12200 PRS_PLINK_5e.04 496.3 Bronchiectasis Both 4 2 9 respiratory coral4 2, 4 1, 0 0, 1 1, 3 1, 0 0.37 708 1 0 1.45 0.497 4.44 -0.00624 21 1 0 0.994 0.908 1.27 0.0722 225 1 0 1.07 0.653 2.79 PRS_PLINK_5e.04 497 Bronchitis Both 5 28 9 respiratory coral4 28, 5 7, 4 7, 1 7, 0 7, 0 -1.12 0.832 0.178 0.75 0.326 0.032 1.78 -1.46 1.82 0.422 0.375 0.232 0.000189 4.14 -2.45 1.98 0.216 0.665 0.0864 8.11e-10 1.55 -1.64 1.64 0.316 0.501 0.193 2.44e-05 2.81 PRS_PLINK_5e.04 498 Acute bronchospasm Both 2 7 9 respiratory coral4 7, 2 2, 1 2, 0 1, 0 2, 1 -0.0171 247 1 0 0.983 0.657 1.22 2.04 136 0.988 0.005 7.69 0.000661 591000 0.00088 38.4 1 0 1 0.955 1.05 2.6 1500 0.999 0.001 13.5 3.2e-05 4610 PRS_PLINK_5e.04 499 Cystic fibrosis Both 2 5 9 respiratory coral4 5, 2 2, 2 1, 0 1, 0 1, 0 2.43 15400 1 0 11.4 5.01e-08 6.94e+08 0.0994 6520000 1 0 1.1 0.22 5.67 -0.303 16700 1 0 0.739 0.0048 70.4 -0.269 6540 1 0 0.764 0.00207 16 PRS_PLINK_5e.04 500 Lung disease due to external agents Both 1 2 9 respiratory coral4 2, 1 1, 0 0, 1 1, 0 1, 0 11.9 748 0.987 0.006 144000 6.18e-08 1170 -0.011 29 1 0 0.989 0.951 1.05 PRS_PLINK_5e.04 500.1 Extrinsic allergic alveolitis Both 1 1 9 respiratory coral4 1, 1 2.23 1.27e+11 1 0 9.33 2.98e-42 7.88e+28 PRS_PLINK_5e.04 501 Pneumonitis due to inhalation of food or vomitus Both 0 10 9 respiratory coral4 10, 0 3 2 2 3 PRS_PLINK_5e.04 502 Postinflammatory pulmonary fibrosis Both 2 7 9 respiratory coral4 7, 2 2, 1 2, 0 1, 0 2, 1 -0.0298 6710000 1 0 0.971 0.0333 4.84 0.284 3270 1 0 1.33 0.453 1.38 -12.1 29500 1 0 5.75e-06 2.99e-20 6.49e+11 0.195 3130000 1 0 1.21 0.032 60.5 PRS_PLINK_5e.04 503 Pulmonary congestion and hypostasis Both 0 11 9 respiratory coral4 11, 0 3 3 2 3 PRS_PLINK_5e.04 504 Other alveolar and parietoalveolar pneumonopathy Both 2 3 9 respiratory coral4 3, 2 1, 1 1, 0 1, 1 1, 1 0.264 3200 1 0 1.3 0.407 15.7 -0.0211 156 1 0 0.979 0.788 1.2 0.724 10000 1 0 2.06 0.15 519 PRS_PLINK_5e.04 504.1 Idiopathic fibrosing alveolitis Both 2 1 9 respiratory coral4 1, 2 0.00726 4.04e+10 1 0 1.01 1.89e-14 2.67e+09 PRS_PLINK_5e.04 505 Other pulmonary inflamation or edema Both 4 19 9 respiratory coral4 19, 4 5, 2 5, 1 4, 0 5, 1 -0.0468 0.913 0.959 0.018 0.954 0.0258 8.96 0.67 2.15 0.756 0.122 1.95 0.0121 1750 3.51 5.73 0.54 0.268 33.6 0.017 2580000 2.32 4.68 0.62 0.207 10.2 0.011 399000 PRS_PLINK_5e.04 506 Empyema and pneumothorax Both 2 23 9 respiratory coral4 23, 2 6, 1 6, 0 5, 0 6, 1 -0.693 0.801 0.387 0.412 0.5 0.0494 2.65 -0.198 2.33 0.932 0.03 0.82 0.00195 120 1.26 2.99 0.674 0.171 3.51 0.0226 1160 -1.38 2.12 0.515 0.288 0.252 0.00315 7.06 PRS_PLINK_5e.04 507 Pleurisy; pleural effusion Both 1 28 9 respiratory coral4 28, 1 6, 1 7, 0 7, 0 7, 0 -0.235 0.704 0.739 0.132 0.791 0.0629 8.1 0.446 2.4 0.853 0.069 1.56 0.00704 180 -0.701 1.9 0.713 0.147 0.496 0.00238 197 0.515 3.05 0.866 0.063 1.67 0.002 816 PRS_PLINK_5e.04 508 Pulmonary collapse; interstitial and compensatory emphysema Both 1 25 9 respiratory coral4 25, 1 7, 0 6, 0 6, 0 6, 1 0.124 0.906 0.891 0.05 1.13 0.0732 24.1 1.16 2.12 0.584 0.234 3.19 0.00933 392 PRS_PLINK_5e.04 509 Respiratory failure, insufficiency, arrest Both 5 37 9 respiratory coral4 37, 5 10, 2 9, 0 9, 1 9, 2 0.0624 0.531 0.906 0.043 1.06 0.337 3.04 0.338 1.75 0.846 0.072 1.4 0.0095 25300 -0.41 1.56 0.793 0.101 0.663 0.0058 65.2 -0.75 1.55 0.628 0.202 0.472 5.59e-05 6.8 PRS_PLINK_5e.04 509.1 Respiratory failure Both 1 24 9 respiratory coral4 24, 1 6, 0 6, 0 6, 1 6, 0 -0.445 0.852 0.602 0.221 0.641 0.0579 4.75 0.933 2.18 0.668 0.175 2.54 0.00781 284 PRS_PLINK_5e.04 509.2 Respiratory insufficiency Both 0 14 9 respiratory coral4 14, 0 4 3 3 4 PRS_PLINK_5e.04 509.3 Pulmonary insufficiency or respiratory failure following trauma and surgery Both 1 13 9 respiratory coral4 13, 1 4, 0 3, 1 3, 0 3, 0 0.696 1.47 0.636 0.197 2.01 0.0816 81.3 -0.0321 2.84 0.991 0.004 0.968 0.49 1.88 PRS_PLINK_5e.04 509.8 Dependence on respirator [Ventilator] or supplemental oxygen Both 3 19 9 respiratory coral4 19, 3 5, 1 5, 0 4, 0 5, 2 0.201 0.763 0.792 0.101 1.22 0.122 5.64 -0.0534 3.41 0.988 0.005 0.948 0.00197 856 -1.51e-14 7.67 1 0 1 1.74e-06 23900 0.927 1.97 0.639 0.195 2.53 0.00219 69.8 PRS_PLINK_5e.04 510 Other diseases of lung Both 9 40 9 respiratory coral4 40, 9 10, 6 10, 0 10, 1 10, 2 -0.568 0.47 0.226 0.645 0.566 0.204 1.32 -2.5 1.54 0.103 0.986 0.082 0.000161 0.905 -1.33 1.29 0.299 0.524 0.263 0.00247 2.28 -1.8 1.53 0.24 0.619 0.165 0.00467 1.92 PRS_PLINK_5e.04 510.2 Lung transplant Both 0 2 9 respiratory coral4 2, 0 1 1 1 1 PRS_PLINK_5e.04 512 Other symptoms of respiratory system Both 31 33 9 respiratory coral4 33, 31 8, 6 8, 6 8, 12 8, 7 0.133 0.302 0.661 0.18 1.14 0.652 2.03 -0.13 0.969 0.894 0.049 0.878 0.161 4.98 1.8 1.08 0.0962 1.017 6.03 0.967 70 0.458 1.05 0.662 0.179 1.58 0.252 15 PRS_PLINK_5e.04 512.1 Wheezing Both 5 16 9 respiratory coral4 16, 5 4, 0 4, 2 4, 2 4, 1 -0.234 0.963 0.808 0.092 0.792 0.0802 33.1 -0.199 28.9 0.995 0.002 0.819 0.118 7.4 -0.00625 15.7 1 0 0.994 0.536 2.03 0.0277 1890 1 0 1.03 0.388 2.9 PRS_PLINK_5e.04 512.2 Painful respiration Both 5 25 9 respiratory coral4 25, 5 6, 1 6, 3 6, 0 6, 1 -0.0131 0.594 0.982 0.008 0.987 0.31 2.92 1.05 1.51 0.487 0.312 2.85 0.0408 97.6 0.709 2.67 0.791 0.102 2.03 0.00444 141 0.638 2.5 0.799 0.098 1.89 9.32e-05 663 PRS_PLINK_5e.04 512.3 Abnormal chest sounds Both 0 3 9 respiratory coral4 3, 0 1 1 1 1 PRS_PLINK_5e.04 512.7 Shortness of breath Both 14 33 9 respiratory coral4 33, 14 8, 2 8, 5 8, 4 8, 3 0.0435 0.379 0.908 0.042 1.04 0.499 2.12 0.955 1.47 0.517 0.287 2.6 0.238 49.6 1.18 1.51 0.436 0.36 3.25 0.248 250 1.9 1.78 0.285 0.546 6.69 0.409 188000 PRS_PLINK_5e.04 512.8 Cough Both 22 33 9 respiratory coral4 33, 22 8, 4 8, 5 8, 7 8, 6 0.2 0.333 0.547 0.262 1.22 0.654 2.29 0.216 1.03 0.833 0.079 1.24 0.214 7.32 1.91 1.48 0.197 0.706 6.75 0.568 843 0.341 1.26 0.787 0.104 1.41 0.152 18.2 PRS_PLINK_5e.04 512.9 Other dyspnea Both 18 33 9 respiratory coral4 33, 18 8, 2 8, 5 8, 7 8, 4 0.322 0.363 0.375 0.426 1.38 0.71 2.77 1.78 1.61 0.271 0.567 5.91 0.505 1650 2.31 1.69 0.171 0.767 10.1 0.593 52900 1.82 1.54 0.24 0.62 6.15 0.54 6040 PRS_PLINK_5e.04 513 Respiratory abnormalities Both 21 43 9 respiratory coral4 43, 21 10, 3 11, 4 10, 9 11, 5 0.126 0.308 0.683 0.165 1.13 0.636 2.02 0.903 1.23 0.463 0.334 2.47 0.258 101 2.97 1.58 0.0603 1.219 19.5 1.01 4060 0.779 1.33 0.557 0.254 2.18 0.108 103 PRS_PLINK_5e.04 513.3 Hypoventilation Both 1 10 9 respiratory coral4 10, 1 3, 0 2, 1 2, 0 3, 0 -0.0676 1.89 0.971 0.013 0.935 0.00778 62.2 -0.11 130000 1 0 0.896 0.691 1.59 PRS_PLINK_5e.04 513.31 Apnea Both 1 5 9 respiratory coral4 5, 1 2, 0 1, 1 1, 0 1, 0 -0.0186 899 1 0 0.982 0.697 1.86 0.0166 5170 1 0 1.02 0.339 5.5 PRS_PLINK_5e.04 513.32 Orthopnea Both 0 2 9 respiratory coral4 2, 0 1 1 1 1 PRS_PLINK_5e.04 513.4 Hyperventilation Both 1 2 9 respiratory coral4 2, 1 1, 1 1, 0 1, 1 1, 0 0.0292 302 1 0 1.03 0.698 1.52 -0.0364 63.6 1 0 0.964 0.935 1.15 PRS_PLINK_5e.04 513.8 Disorders of diaphragm Both 0 3 9 respiratory coral4 3, 0 1 1 1 1 PRS_PLINK_5e.04 514 Abnormal findings examination of lungs Both 6 41 9 respiratory coral4 41, 6 11, 3 10, 1 10, 1 10, 1 -0.14 0.544 0.797 0.099 0.869 0.283 2.77 0.377 1.68 0.822 0.085 1.46 0.0494 1080 -0.19 1.44 0.895 0.048 0.827 0.0106 644 -1.57 2.01 0.433 0.363 0.208 5.88e-05 105 PRS_PLINK_5e.04 514.1 Abnormal results of function study of pulmonary system Both 0 2 9 respiratory coral4 2, 0 1 1 1 1 PRS_PLINK_5e.04 514.2 Solitary pulmonary nodule Both 3 25 9 respiratory coral4 25, 3 7, 2 6, 0 6, 1 6, 0 -0.0858 0.744 0.908 0.042 0.918 0.0816 10 0.313 2.34 0.893 0.049 1.37 0.00762 125 0.244 1.91 0.899 0.046 1.28 0.0324 104 -0.175 2.55 0.945 0.024 0.839 0.00149 51.5 PRS_PLINK_5e.04 516 Abnormal sputum Both 3 10 9 respiratory coral4 10, 3 3, 2 2, 1 2, 0 3, 0 -1.19 1.67 0.475 0.324 0.304 0.0105 5.69 -0.157 796 1 0 0.854 0.381 0.554 0.00479 314 1 0 1 0.837 1.48 -0.873 459 0.998 0.001 0.418 0.165 0.71 PRS_PLINK_5e.04 516.1 Hemoptysis Both 3 11 9 respiratory coral4 11, 3 3, 2 3, 1 2, 0 3, 0 -0.925 1.32 0.483 0.316 0.396 0.0159 7.29 -0.387 48.6 0.994 0.003 0.679 0.653 167 -0.00189 627 1 0 0.998 0.66 4.11 -1.08 439 0.998 0.001 0.34 0.208 2.2 PRS_PLINK_5e.04 519 Other diseases of respiratory system, not elsewhere classified Both 8 54 9 respiratory coral4 54, 8 14, 1 13, 2 13, 2 14, 3 0.321 0.427 0.452 0.345 1.38 0.574 3.51 0.955 1.4 0.494 0.306 2.6 0.0725 577 0.448 1.2 0.709 0.15 1.57 0.0641 41.1 0.0973 1.27 0.939 0.027 1.1 6.95e-06 112 PRS_PLINK_5e.04 519.1 Tracheostomy complications Both 0 1 9 respiratory coral4 1, 0 PRS_PLINK_5e.04 519.2 Respiratory complications Both 0 4 9 respiratory coral4 4, 0 1 1 1 1 PRS_PLINK_5e.04 519.8 Other diseases of respiratory system, NEC Both 4 23 9 respiratory coral4 23, 4 6, 1 6, 1 5, 1 6, 1 0.933 1.22 0.443 0.354 2.54 0.129 175000 0.183 2.71 0.946 0.024 1.2 0.0059 946 0.35 4.01 0.93 0.031 1.42 0.00355 1.55e+09 2.72 6.59 0.68 0.168 15.2 0.00123 17.7 PRS_PLINK_5e.04 519.9 Symptoms involving respiratory system and other chest symptoms Both 6 43 9 respiratory coral4 43, 6 11, 1 11, 2 10, 2 11, 1 -0.0307 0.47 0.948 0.023 0.97 0.311 2.59 1.61 1.98 0.417 0.38 4.99 0.104 92000 0.37 1.41 0.793 0.1 1.45 0.0138 87.6 -0.552 1.4 0.692 0.16 0.576 0.00282 13.7 PRS_PLINK_5e.04 520 Disorders of tooth development Both 0 8 10 digestive chartreuse4 8, 0 2 2 2 2 PRS_PLINK_5e.04 520.1 Hereditary disturbances in tooth structure Both 0 5 10 digestive chartreuse4 5, 0 2 1 1 1 PRS_PLINK_5e.04 520.2 Disturbances in tooth eruption Both 0 9 10 digestive chartreuse4 9, 0 3 2 2 2 PRS_PLINK_5e.04 521 Diseases of hard tissues of teeth Both 0 13 10 digestive chartreuse4 13, 0 4 3 3 3 PRS_PLINK_5e.04 521.1 Dental caries Both 0 12 10 digestive chartreuse4 12, 0 3 3 3 3 PRS_PLINK_5e.04 522 Diseases of pulp and periapical tissues Both 1 7 10 digestive chartreuse4 7, 1 2, 1 2, 0 1, 0 2, 0 3.78e-06 63.1 1 0 1 0.0128 89 -0.35 5840 1 0 0.704 0.346 1.6 -0.645 6470 1 0 0.525 0.0142 3.95 0.599 3350 1 0 1.82 0.314 2.8 PRS_PLINK_5e.04 522.5 Periapical abscess Both 1 5 10 digestive chartreuse4 5, 1 2, 0 1, 0 1, 1 1, 0 0.0653 1480 1 0 1.07 0.772 2.41 -0.235 34000 1 0 0.791 0.165 2.51 PRS_PLINK_5e.04 523 Gingival and periodontal diseases Both 0 10 10 digestive chartreuse4 10, 0 3 2 2 3 PRS_PLINK_5e.04 523.1 Gingivitis Both 0 3 10 digestive chartreuse4 3, 0 1 1 1 1 PRS_PLINK_5e.04 523.3 Periodontitis (acute or chronic) Both 0 4 10 digestive chartreuse4 4, 0 1 1 1 1 PRS_PLINK_5e.04 523.31 Acute periodontitis Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_5e.04 523.32 Chronic periodontitis Both 0 1 10 digestive chartreuse4 1, 0 PRS_PLINK_5e.04 524 Dentofacial anomalies, including malocclusion Both 2 6 10 digestive chartreuse4 6, 2 1, 0 1, 2 1, 0 2, 0 -0.0491 104 1 0 0.952 0.762 1.13 -0.0099 1420 1 0 0.99 0.899 1.43 PRS_PLINK_5e.04 524.3 Anomalies of tooth position/malocclusion Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_5e.04 525 Other diseases of the teeth and supporting structures Both 1 17 10 digestive chartreuse4 17, 1 4, 0 4, 1 4, 0 4, 0 0.203 0.943 0.829 0.081 1.23 0.202 10.1 0.574 23200000 1 0 1.78 0.0938 952 PRS_PLINK_5e.04 525.1 Loss of teeth or edentulism Both 0 7 10 digestive chartreuse4 7, 0 2 2 1 2 PRS_PLINK_5e.04 526 Diseases of the jaws Both 4 37 10 digestive chartreuse4 37, 4 9, 0 9, 3 9, 1 9, 0 0.0192 0.582 0.974 0.012 1.02 0.208 4.19 2.16 1.97 0.274 0.562 8.65 0.357 1720 0.54 2.11 0.798 0.098 1.72 0.0256 1530 PRS_PLINK_5e.04 526.1 Cysts of the jaws Both 1 6 10 digestive chartreuse4 6, 1 2, 1 1, 0 1, 0 2, 0 -0.000393 643 1 0 1 0.964 1.25 -0.00109 9.14 1 0 0.999 0.981 1.01 0.0208 153 1 0 1.02 0.902 1.09 -0.00388 96 1 0 0.996 0.923 1.1 PRS_PLINK_5e.04 526.3 Anomalies of jaw size/symmetry Both 1 2 10 digestive chartreuse4 2, 1 1, 0 1, 1 1, 0 1, 1 0.0127 81.3 1 0 1.01 0.956 1.14 0.0267 143 1 0 1.03 0.889 1.28 PRS_PLINK_5e.04 526.4 Temporomandibular joint disorders Both 2 20 10 digestive chartreuse4 20, 2 5, 0 5, 2 5, 0 5, 0 0.124 0.962 0.897 0.047 1.13 0.179 8.47 2.22 2.9 0.444 0.353 9.22 0.0218 47800 PRS_PLINK_5e.04 526.41 Temporomandibular joint disorder, unspecified Both 2 17 10 digestive chartreuse4 17, 2 5, 0 4, 2 4, 0 4, 0 0.179 1.05 0.865 0.063 1.2 0.178 8.33 1.81 2.16 0.404 0.394 6.09 0.16 1280 PRS_PLINK_5e.04 526.42 Arthralgia/ankylosis of temporomandibular joint Both 1 9 10 digestive chartreuse4 9, 1 3, 0 2, 1 2, 0 2, 0 5.08e-12 34.2 1 0 1 6.95e-05 14100 0.103 1680 1 0 1.11 0.617 1.53 PRS_PLINK_5e.04 526.5 Inflammatory conditions of jaw Both 0 3 10 digestive chartreuse4 3, 0 1 1 1 1 PRS_PLINK_5e.04 526.9 Jaw disease NOS Both 0 8 10 digestive chartreuse4 8, 0 2 2 2 2 PRS_PLINK_5e.04 527 Diseases of the salivary glands Both 3 18 10 digestive chartreuse4 18, 3 5, 1 4, 0 4, 1 5, 1 -0.278 0.867 0.748 0.126 0.757 0.0197 5.33 0.291 3.13 0.926 0.033 1.34 0.0108 190 0.797 3.43 0.816 0.088 2.22 0.0172 5630 -0.594 3.01 0.844 0.074 0.552 0.00383 52.1 PRS_PLINK_5e.04 527.1 Hypertrophy of salivary gland Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_5e.04 527.2 Sialoadenitis Both 1 5 10 digestive chartreuse4 5, 1 1, 1 1, 0 1, 0 1, 0 -0.301 6810 1 0 0.74 0.607 1.89 0.146 95900 1 0 1.16 0.147 9.14 0.00312 114 1 0 1 0.965 1.08 0.00111 42 1 0 1 0.983 1.02 PRS_PLINK_5e.04 527.7 Disturbance of salivary secretion Both 2 7 10 digestive chartreuse4 7, 2 2, 0 2, 0 1, 1 2, 1 -1.02 57.7 0.986 0.006 0.362 0.000939 108 0.101 5490 1 0 1.11 0.572 4.21 6.44 1780 0.997 0.001 626 3.84e-13 172000 PRS_PLINK_5e.04 527.8 Other specified diseases of the salivary glands Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_5e.04 528 Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue Both 6 34 10 digestive chartreuse4 34, 6 9, 3 8, 2 8, 0 9, 1 -0.864 0.604 0.153 0.816 0.421 0.0551 1.22 -1.08 1.41 0.445 0.352 0.34 0.000346 3.8 -2.07 1.8 0.251 0.601 0.126 0.000193 3.99 -0.757 1.91 0.693 0.16 0.469 2.62e-06 94.7 PRS_PLINK_5e.04 528.1 Stomatitis and mucositis Both 1 9 10 digestive chartreuse4 9, 1 3, 0 2, 0 2, 0 2, 1 -0.149 18.4 0.994 0.003 0.861 0.133 5.68 0.555 3920 1 0 1.74 0.00514 2.11 PRS_PLINK_5e.04 528.11 Stomatitis and mucositis (ulcerative) Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_5e.04 528.12 Oral aphthae Both 1 3 10 digestive chartreuse4 3, 1 1, 0 1, 0 1, 1 1, 0 -0.0318 815 1 0 0.969 0.945 1.28 -0.0299 39.1 0.999 0 0.971 0.833 1.05 PRS_PLINK_5e.04 528.3 Cellulitis and abscess of oral soft tissues Both 0 7 10 digestive chartreuse4 7, 0 2 2 1 2 PRS_PLINK_5e.04 528.4 Cysts of oral soft tissues Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_5e.04 528.5 Diseases of lips Both 1 5 10 digestive chartreuse4 5, 1 2, 1 1, 0 1, 0 1, 0 0.151 4210 1 0 1.16 0.0156 37.6 0.0173 2660 1 0 1.02 0.473 1.39 0.0133 1650 1 0 1.01 0.648 1.8 0.0765 10500 1 0 1.08 0.284 4.3 PRS_PLINK_5e.04 528.6 Leukoplakia of oral mucosa Both 2 2 10 digestive chartreuse4 2, 2 1, 1 1, 1 1, 1 1, 1 -0.0501 649 1 0 0.951 0.879 1.85 -0.0414 1080 1 0 0.959 0.689 3.15 PRS_PLINK_5e.04 528.7 Sialolithiasis Both 0 1 10 digestive chartreuse4 1, 0 PRS_PLINK_5e.04 529 Diseases and other conditions of the tongue Both 1 5 10 digestive chartreuse4 5, 1 2, 1 1, 0 1, 0 1, 0 -0.504 942 1 0 0.604 0.0761 2.64 2.43e-05 5850 1 0 1 0.346 29.4 -0.0066 1260 1 0 0.993 0.231 1.35 -2.84e-07 6640 1 0 1 0.34 37.3 PRS_PLINK_5e.04 529.1 Glossitis Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_5e.04 529.6 Glossodynia Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_5e.04 530 Diseases of esophagus Both 26 36 10 digestive chartreuse4 36, 26 8, 11 9, 5 9, 2 9, 8 0.0746 0.285 0.794 0.1 1.08 0.642 1.82 -1.42 0.939 0.13 0.887 0.241 0.0318 1.13 -0.729 0.938 0.437 0.359 0.482 0.0881 2.4 -0.264 0.798 0.741 0.13 0.768 0.183 3.13 PRS_PLINK_5e.04 530.1 Esophagitis, GERD and related diseases Both 25 36 10 digestive chartreuse4 36, 25 8, 11 9, 4 9, 2 9, 8 0.0888 0.286 0.756 0.122 1.09 0.651 1.85 -1.46 0.932 0.117 0.931 0.232 0.0327 1.08 -0.729 0.938 0.437 0.359 0.482 0.0881 2.4 -0.264 0.798 0.741 0.13 0.768 0.183 3.13 PRS_PLINK_5e.04 530.11 GERD Both 24 36 10 digestive chartreuse4 36, 24 8, 11 9, 3 9, 2 9, 8 0.0925 0.286 0.747 0.127 1.1 0.653 1.85 -1.67 0.986 0.0896 1.048 0.187 0.0225 0.935 -0.729 0.938 0.437 0.359 0.482 0.0881 2.4 -0.264 0.798 0.741 0.13 0.768 0.183 3.13 PRS_PLINK_5e.04 530.13 Barrett's esophagus Both 0 10 10 digestive chartreuse4 10, 0 3 2 2 3 PRS_PLINK_5e.04 530.14 Reflux esophagitis Both 6 21 10 digestive chartreuse4 21, 6 6, 3 5, 1 5, 0 5, 2 -0.53 0.635 0.404 0.394 0.588 0.0707 1.77 0.0935 2.42 0.969 0.014 1.1 0.0174 59.7 -1.29 1.97 0.513 0.29 0.275 0.00642 4.06 0.156 1.5 0.917 0.038 1.17 0.00149 39.5 PRS_PLINK_5e.04 530.15 Eosinophilic esophagitis Both 1 5 10 digestive chartreuse4 5, 1 2, 1 1, 0 1, 0 1, 0 -0.0638 2970 1 0 0.938 0.766 2.76 1.28 4.88e+08 1 0 3.61 0.153 182 -0.976 15000 1 0 0.377 8.36e-06 15100 -11.5 44500 1 0 9.91e-06 5.2e-20 11500000 PRS_PLINK_5e.04 530.2 Esophageal bleeding (varices/hemorrhage) Both 0 6 10 digestive chartreuse4 6, 0 2 1 1 2 PRS_PLINK_5e.04 530.3 Stricture and stenosis of esophagus Both 1 9 10 digestive chartreuse4 9, 1 3, 1 2, 0 2, 0 2, 0 -0.531 1.85 0.775 0.111 0.588 0.571 0.604 0.117 1310 1 0 1.12 0.708 1.28 -0.263 5890 1 0 0.769 0.406 1.71 0.0428 2940 1 0 1.04 0.566 2.74 PRS_PLINK_5e.04 530.5 Disorders of esophageal motility Both 1 6 10 digestive chartreuse4 6, 1 2, 1 1, 0 1, 0 2, 0 -0.139 600 1 0 0.87 0.515 1.26 0.102 5400 1 0 1.11 0.631 3.68 0.000284 49.5 1 0 1 0.873 1.09 -0.0961 419 1 0 0.908 0.592 0.963 PRS_PLINK_5e.04 530.6 Diverticulum of esophagus, acquired Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_5e.04 530.7 Gastroesophageal laceration-hemorrhage syndrome Both 2 1 10 digestive chartreuse4 1, 2 -0.0788 592 1 0 0.924 0.0979 1.26 PRS_PLINK_5e.04 530.9 Heartburn Both 2 21 10 digestive chartreuse4 21, 2 6, 1 5, 0 5, 0 5, 1 0.125 0.764 0.87 0.061 1.13 0.257 7.71 -0.0795 3.05 0.979 0.009 0.924 0.00757 56.4 -1.15 3.94 0.77 0.114 0.315 2.87e-10 73.8 -0.419 1.77 0.813 0.09 0.658 0.0293 11.4 PRS_PLINK_5e.04 531 Peptic ulcer (excl. esophageal) Both 3 17 10 digestive chartreuse4 17, 3 5, 2 4, 0 4, 0 4, 1 0.1 0.61 0.869 0.061 1.11 0.354 3.32 -0.671 7.37 0.927 0.033 0.511 0.488 0.537 5.01 85.1 0.953 0.021 149 108 205 0.381 3.06 0.901 0.045 1.46 0.0166 150 PRS_PLINK_5e.04 531.1 Hemorrhage from gastrointestinal ulcer Both 1 1 10 digestive chartreuse4 1, 1 -0.00717 93 1 0 0.993 0.862 1.12 PRS_PLINK_5e.04 531.2 Gastric ulcer Both 3 10 10 digestive chartreuse4 10, 3 3, 2 2, 0 2, 0 3, 1 -0.836 8.24 0.919 0.037 0.434 0.412 0.455 0.549 24800 1 0 1.73 0.157 2.91 0.143 928 1 0 1.15 0.575 4.32 -0.33 5640000 1 0 0.719 0.000142 38200 PRS_PLINK_5e.04 531.3 Duodenal ulcer Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_5e.04 531.4 Peptic ulcer, site unspecified Both 1 7 10 digestive chartreuse4 7, 1 2, 0 2, 0 1, 0 2, 1 1.03 76.1 0.989 0.005 2.81 2.67 6.57 -0.238 3870 1 0 0.788 0.0792 5.98 PRS_PLINK_5e.04 531.5 Gastrojejunal ulcer Both 0 1 10 digestive chartreuse4 1, 0 PRS_PLINK_5e.04 532 Dysphagia Both 7 34 10 digestive chartreuse4 34, 7 9, 2 8, 3 8, 0 9, 2 -0.177 0.494 0.721 0.142 0.838 0.307 2.08 0.319 1.24 0.797 0.099 1.38 0.137 13.9 -1.41 1.81 0.437 0.359 0.244 0.00087 6.34 -0.951 1.35 0.483 0.316 0.386 0.000765 4.04 PRS_PLINK_5e.04 535 Gastritis and duodenitis Both 10 31 10 digestive chartreuse4 31, 10 8, 5 8, 3 7, 0 8, 2 -0.94 0.557 0.0916 1.038 0.39 0.112 1.02 -1.37 1.35 0.311 0.507 0.255 0.00901 3.14 -3.55 2.54 0.162 0.791 0.0287 3.63e-05 1.57 -1.31 1.55 0.397 0.402 0.27 0.00194 3.78 PRS_PLINK_5e.04 535.1 Acute gastritis Both 2 11 10 digestive chartreuse4 11, 2 3, 2 3, 0 2, 0 3, 0 0.089 1.41 0.95 0.022 1.09 0.157 14.5 -0.173 1020000 1 0 0.841 0.348 1.13 -0.193 167 0.999 0 0.824 0.176 3.5 -0.0695 7580000 1 0 0.933 0.00235 239 PRS_PLINK_5e.04 535.2 Atrophic gastritis Both 3 1 10 digestive chartreuse4 1, 3 1.85 13500 1 0 6.33 0.00491 5660 PRS_PLINK_5e.04 535.6 Duodenitis Both 1 3 10 digestive chartreuse4 3, 1 1, 1 1, 0 1, 0 1, 1 -0.223 3090 1 0 0.8 0.154 1.61 0.011 37.4 1 0 1.01 0.861 1.26 0.0113 41.2 1 0 1.01 0.505 1.43 PRS_PLINK_5e.04 535.8 Other specified gastritis Both 2 7 10 digestive chartreuse4 7, 2 2, 1 2, 0 1, 0 2, 1 1.08 7.72 0.889 0.051 2.93 2.81 3.08 0.203 1490 1 0 1.22 0.59 1.84 -6.2 47900 1 0 0.00202 1.91e-13 2.38e+09 0.041 205 1 0 1.04 0.82 1.37 PRS_PLINK_5e.04 535.9 Gastritis and duodenitis, NOS Both 2 15 10 digestive chartreuse4 15, 2 4, 1 4, 1 3, 0 4, 0 -0.146 1.19 0.902 0.045 0.864 0.0309 6.32 0.42 3.56 0.906 0.043 1.52 0.00432 623 0.0718 732 1 0 1.07 0.835 1.23 1.51 4.6 0.744 0.129 4.51 0.879 40.8 PRS_PLINK_5e.04 536 Disorders of function of stomach Both 15 30 10 digestive chartreuse4 30, 15 7, 7 7, 4 7, 2 8, 2 -0.451 0.45 0.317 0.499 0.637 0.264 1.4 -1 1.13 0.374 0.427 0.368 0.0413 2.48 -0.326 1.25 0.795 0.1 0.722 0.072 8.37 0.34 2.11 0.872 0.059 1.41 0.000934 16200 PRS_PLINK_5e.04 536.3 Gastroparesis Both 6 16 10 digestive chartreuse4 16, 6 3, 2 4, 1 4, 2 4, 1 -0.527 0.675 0.435 0.362 0.59 0.137 1.74 -0.253 3.64 0.945 0.025 0.777 1.75e-05 7000 0.269 2.89 0.926 0.034 1.31 1.27 1.34 -1.18 2.15 0.585 0.233 0.308 0.00918 5.8 PRS_PLINK_5e.04 536.7 Complications of gastrostomy, colostomy and enterostomy Both 2 2 10 digestive chartreuse4 2, 2 1, 2 1, 0 1, 2 1, 0 0.188 257 0.999 0 1.21 0.803 1.22 -0.00279 274 1 0 0.997 0.782 1.38 PRS_PLINK_5e.04 536.8 Dyspepsia and other specified disorders of function of stomach Both 9 25 10 digestive chartreuse4 25, 9 6, 3 6, 3 6, 2 6, 1 -0.0547 0.523 0.917 0.038 0.947 0.347 2.41 0.655 1.9 0.73 0.137 1.92 0.0109 514 -0.684 1.72 0.69 0.161 0.505 0.0176 7.6 0.119 1.82 0.948 0.023 1.13 0.0162 235 PRS_PLINK_5e.04 537 Other disorders of stomach and duodenum Both 12 33 10 digestive chartreuse4 33, 12 8, 5 8, 3 8, 1 8, 3 -0.135 0.376 0.72 0.142 0.874 0.422 1.68 -1.28 1.35 0.341 0.467 0.278 0.0118 2.59 -0.257 1.65 0.876 0.057 0.773 0.00186 51.2 -0.659 1.25 0.599 0.222 0.517 0.024 4.41 PRS_PLINK_5e.04 537.1 Lesions of stomach and duodenum Both 0 1 10 digestive chartreuse4 1, 0 PRS_PLINK_5e.04 539 Bariatric surgery Both 1 27 10 digestive chartreuse4 27, 1 7, 0 7, 0 6, 0 7, 1 0.215 0.829 0.796 0.099 1.24 0.0799 39.8 0.0753 2.36 0.975 0.011 1.08 0.00303 87.5 PRS_PLINK_5e.04 540 Appendiceal conditions Both 0 6 10 digestive chartreuse4 6, 0 2 1 1 2 PRS_PLINK_5e.04 540.1 Appendicitis Both 0 3 10 digestive chartreuse4 3, 0 1 1 1 1 PRS_PLINK_5e.04 540.11 Acute appendicitis Both 0 3 10 digestive chartreuse4 3, 0 1 1 1 1 PRS_PLINK_5e.04 550 Abdominal hernia Both 9 49 10 digestive chartreuse4 49, 9 12, 3 12, 2 12, 0 12, 4 0.00775 0.392 0.984 0.007 1.01 0.437 2.17 -1.69 1.22 0.163 0.787 0.184 0.00866 1.46 -1.34 1.34 0.318 0.498 0.262 0.00294 2.68 0.0317 1.05 0.976 0.011 1.03 0.138 7.51 PRS_PLINK_5e.04 550.1 Inguinal hernia Both 3 20 10 digestive chartreuse4 20, 3 4, 1 5, 1 5, 0 5, 1 0.196 0.601 0.744 0.129 1.22 0.355 4.07 -0.137 2.21 0.951 0.022 0.872 0.709 0.972 -1.14 24.9 0.963 0.016 0.321 0.0584 0.131 -1.46 14.5 0.92 0.036 0.233 0.211 0.259 PRS_PLINK_5e.04 550.2 Diaphragmatic hernia Both 5 28 10 digestive chartreuse4 28, 5 7, 2 7, 1 7, 0 7, 2 -0.549 0.655 0.402 0.396 0.578 0.124 1.87 -1.01 1.88 0.589 0.23 0.363 1.27e-06 9.02 -0.631 1.69 0.709 0.149 0.532 0.0125 191 -1.17 2.21 0.597 0.224 0.31 7.18e-05 178 PRS_PLINK_5e.04 550.3 Femoral hernia Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_5e.04 550.4 Umbilical hernia Both 1 13 10 digestive chartreuse4 13, 1 4, 1 3, 0 3, 0 3, 0 -0.751 2.46 0.76 0.119 0.472 0.00247 34 -0.0121 2.81 0.997 0.001 0.988 0.184 8.15 -0.437 2970 1 0 0.646 0.0497 0.38 0.122 1750000 1 0 1.13 0.583 2.38 PRS_PLINK_5e.04 550.5 Ventral hernia Both 3 22 10 digestive chartreuse4 22, 3 6, 1 5, 1 5, 0 6, 1 0.000158 0.79 1 0 1 0.231 4.68 -0.609 2.73 0.823 0.084 0.544 0.457 711 -0.337 2.18 0.878 0.057 0.714 0.00662 27.8 0.769 7.9 0.923 0.035 2.16 1e-05 1.18e+08 PRS_PLINK_5e.04 550.6 Incisional hernia Both 0 13 10 digestive chartreuse4 13, 0 4 3 3 3 PRS_PLINK_5e.04 555 Inflammatory bowel disease and other gastroenteritis and colitis Both 5 11 10 digestive chartreuse4 11, 5 3, 1 3, 1 2, 1 3, 2 0.301 1.05 0.773 0.112 1.35 0.237 9.52 0.224 3350000 1 0 1.25 0.0203 34.2 -0.934 15100000 1 0 0.393 0.00162 68.3 -0.565 24.2 0.981 0.008 0.569 0.458 0.695 PRS_PLINK_5e.04 555.1 Regional enteritis Both 1 9 10 digestive chartreuse4 9, 1 3, 0 2, 0 2, 0 2, 1 0.253 10.6 0.981 0.008 1.29 1.16e-07 3690000 0.0227 5970 1 0 1.02 0.35 2.31 PRS_PLINK_5e.04 555.2 Ulcerative colitis Both 4 6 10 digestive chartreuse4 6, 4 2, 1 1, 1 1, 1 2, 1 0.586 28 0.983 0.007 1.8 1.33e-05 2.16 -0.0134 277 1 0 0.987 0.975 1.24 0.114 1820 1 0 1.12 0.574 2.35 -0.734 151 0.996 0.002 0.48 0.000212 9120 PRS_PLINK_5e.04 555.21 Ulcerative colitis (chronic) Both 4 5 10 digestive chartreuse4 5, 4 1, 1 1, 0 1, 1 1, 2 0.0723 70.2 0.999 0 1.08 0.825 2.25 0.036 120 1 0 1.04 0.716 1.49 -0.388 4660 1 0 0.679 0.596 6.71 -0.471 1970 1 0 0.624 0.504 2.06 PRS_PLINK_5e.04 556 Ulceration of the lower GI tract Both 0 7 10 digestive chartreuse4 7, 0 2 2 1 2 PRS_PLINK_5e.04 556.1 Ulceration of intestine Both 0 5 10 digestive chartreuse4 5, 0 2 1 1 1 PRS_PLINK_5e.04 556.11 Angiodysplasia of intestine (without mention of hemorrhage) Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_5e.04 557 Intestinal malabsorption (non-celiac) Both 7 19 10 digestive chartreuse4 19, 7 4, 3 5, 1 4, 1 5, 2 -0.306 0.616 0.619 0.208 0.736 0.233 2.08 -0.555 1.61 0.73 0.137 0.574 0.0268 5.14 2.86 15.6 0.855 0.068 17.5 13.6 22.3 -1.11 2.73 0.684 0.165 0.329 0.00219 19.1 PRS_PLINK_5e.04 557.1 Celiac disease Both 4 8 10 digestive chartreuse4 8, 4 1, 2 2, 1 2, 0 2, 1 -0.305 1.09 0.779 0.108 0.737 0.673 3.98 0.0115 17.4 0.999 0 1.01 0.8 1.05 0.302 7040 1 0 1.35 0.378 2.04 -0.134 772 1 0 0.875 0.823 1.35 PRS_PLINK_5e.04 558 Noninfectious gastroenteritis Both 11 23 10 digestive chartreuse4 23, 11 5, 3 6, 1 5, 4 6, 3 -0.147 0.559 0.793 0.101 0.863 0.285 2.31 -1.43 1.54 0.352 0.453 0.24 0.00502 4.31 1.36 1.81 0.453 0.344 3.88 0.26 1240 -1.11 1.94 0.567 0.247 0.33 0.00547 6.47 PRS_PLINK_5e.04 559 Ileostomy status Both 0 7 10 digestive chartreuse4 7, 0 2 2 1 2 PRS_PLINK_5e.04 560 Intestinal obstruction without mention of hernia Both 5 20 10 digestive chartreuse4 20, 5 5, 1 5, 1 5, 1 5, 2 0.194 0.938 0.837 0.078 1.21 0.222 7.8 -0.498 1.81 0.784 0.106 0.608 0.0195 27.4 0.61 2.07 0.768 0.115 1.84 0.0783 70.7 -2.71 4.73 0.567 0.246 0.0667 1.71e-06 73.2 PRS_PLINK_5e.04 560.1 Paralytic ileus Both 3 9 10 digestive chartreuse4 9, 3 3, 0 2, 1 2, 0 2, 2 1.12 2.56 0.66 0.18 3.08 0.101 3.5 0.0271 787 1 0 1.03 0.873 1.19 0.426 1720 1 0 1.53 4.73e-05 3830 PRS_PLINK_5e.04 560.2 Impaction of intestine Both 2 1 10 digestive chartreuse4 1, 2 -0.0287 811 1 0 0.972 0.267 1.75 PRS_PLINK_5e.04 560.3 Peritoneal or intestinal adhesions Both 0 1 10 digestive chartreuse4 1, 0 PRS_PLINK_5e.04 560.4 Other intestinal obstruction Both 2 13 10 digestive chartreuse4 13, 2 4, 0 3, 1 3, 0 3, 1 0.11 1.65 0.947 0.024 1.12 0.0189 17.4 -0.376 5010 1 0 0.687 0.598 1.62 0.366 21600000 1 0 1.44 0.0126 206 PRS_PLINK_5e.04 561 Symptoms involving digestive system Both 7 21 10 digestive chartreuse4 21, 7 6, 2 5, 1 5, 2 5, 2 0.161 0.746 0.829 0.082 1.18 0.321 4.95 -0.545 1.63 0.738 0.132 0.58 0.487 0.762 1.5 1.97 0.446 0.351 4.5 0.219 293 0.164 2.7 0.952 0.022 1.18 0.00437 78.4 PRS_PLINK_5e.04 562 Diverticulosis and diverticulitis Both 6 21 10 digestive chartreuse4 21, 6 6, 1 5, 3 5, 1 5, 1 -0.39 0.897 0.663 0.178 0.677 0.0397 4.4 0.457 1.48 0.757 0.121 1.58 0.132 158 -0.244 2.7 0.928 0.032 0.784 0.00366 64.3 1.09 3.5 0.756 0.121 2.96 0.00187 257 PRS_PLINK_5e.04 562.1 Diverticulosis Both 6 21 10 digestive chartreuse4 21, 6 6, 1 5, 3 5, 1 5, 1 -0.39 0.897 0.663 0.178 0.677 0.0397 4.4 0.457 1.48 0.757 0.121 1.58 0.132 158 -0.244 2.7 0.928 0.032 0.784 0.00366 64.3 1.09 3.5 0.756 0.121 2.96 0.00187 257 PRS_PLINK_5e.04 562.2 Diverticulitis Both 1 14 10 digestive chartreuse4 14, 1 4, 0 3, 0 3, 0 4, 1 0.237 1.44 0.869 0.061 1.27 0.000913 16.7 2.19 19.5 0.911 0.041 8.96 0.0428 10 PRS_PLINK_5e.04 564 Functional digestive disorders Both 27 27 10 digestive chartreuse4 27, 27 6, 7 7, 6 6, 7 7, 7 0.146 0.325 0.653 0.185 1.16 0.645 2.11 0.245 0.994 0.805 0.094 1.28 0.233 8.24 -0.596 1.39 0.667 0.176 0.551 0.00311 9.58 -0.043 0.962 0.964 0.016 0.958 0.185 5.15 PRS_PLINK_5e.04 564.1 Irritable Bowel Syndrome Both 5 23 10 digestive chartreuse4 23, 5 6, 2 6, 1 5, 2 6, 0 -0.78 0.761 0.306 0.515 0.459 0.0773 1.65 -0.665 1.58 0.673 0.172 0.514 0.00726 6.89 -0.65 1.87 0.728 0.138 0.522 0.00366 11.8 -1.96 2.48 0.429 0.367 0.141 0.000104 6 PRS_PLINK_5e.04 564.9 Personal history of diseases of digestive system Both 5 20 10 digestive chartreuse4 20, 5 5, 2 5, 0 5, 2 5, 1 1.37 1.29 0.289 0.539 3.93 0.423 45 -2.17 3.29 0.509 0.294 0.114 0.000106 17.4 0.187 3.07 0.951 0.022 1.21 0.00466 238 -1.12 3.21 0.726 0.139 0.325 4.62e-05 43.6 PRS_PLINK_5e.04 565 Anal and rectal conditions Both 11 31 10 digestive chartreuse4 31, 11 8, 5 8, 0 7, 3 8, 3 -0.179 0.426 0.675 0.171 0.836 0.382 1.8 -1.61 1.44 0.262 0.582 0.2 0.00416 2.1 0.291 1.09 0.789 0.103 1.34 0.223 13.4 -0.582 1.2 0.629 0.202 0.559 0.0405 4.51 PRS_PLINK_5e.04 565.1 Anal and rectal polyp Both 3 9 10 digestive chartreuse4 9, 3 3, 1 2, 0 2, 2 2, 0 -2.66 3.39 0.432 0.364 0.0697 3.78e-07 5.46 -0.154 4500 1 0 0.857 4.76e-06 379 0.649 8820000 1 0 1.91 0.00251 533 -0.0965 2360 1 0 0.908 0.746 2.1 PRS_PLINK_5e.04 567 Peritonitis and retroperitoneal infections Both 1 7 10 digestive chartreuse4 7, 1 2, 0 2, 0 1, 0 2, 1 -0.103 379 1 0 0.902 0.274 3.73 5.55 1570 0.997 0.001 257 6.28e-14 3.46e+16 PRS_PLINK_5e.04 568 Other disorders of peritoneum Both 1 12 10 digestive chartreuse4 12, 1 3, 1 3, 0 3, 0 3, 0 -0.704 1.14 0.538 0.27 0.494 0.0402 7.89 -0.0886 827 1 0 0.915 0.163 1.56 -0.0682 747 1 0 0.934 0.7 1.17 0.371 1320 1 0 1.45 0.148 20.6 PRS_PLINK_5e.04 568.1 Peritoneal adhesions (postoperative) (postinfection) Both 1 9 10 digestive chartreuse4 9, 1 3, 1 2, 0 2, 0 2, 0 -1.11 3.82 0.771 0.113 0.329 0.316 4.1 0.0218 2190 1 0 1.02 0.471 8.4 0.186 4960 1 0 1.2 0.154 11.9 -0.0879 941 1 0 0.916 0.343 1.56 PRS_PLINK_5e.04 569 Other disorders of intestine Both 18 39 10 digestive chartreuse4 39, 18 10, 7 10, 6 9, 3 10, 2 -0.629 0.404 0.12 0.921 0.533 0.237 1.09 -0.676 0.91 0.457 0.34 0.508 0.0833 2.44 0.257 1 0.797 0.098 1.29 0.229 8.12 -0.78 1.21 0.519 0.285 0.459 0.0294 3.35 PRS_PLINK_5e.04 569.1 Toxic gastroenteritis and colitis Both 0 3 10 digestive chartreuse4 3, 0 1 1 1 1 PRS_PLINK_5e.04 569.2 Gastrointestinal complications Both 2 17 10 digestive chartreuse4 17, 2 5, 1 4, 0 4, 0 4, 1 -0.138 1.35 0.919 0.037 0.871 0.0265 20.8 1.08 5.45 0.843 0.074 2.94 2.74 3.16 0.672 3.34 0.841 0.075 1.96 0.0149 801 -4.6 94.1 0.961 0.017 0.01 0.00753 0.0134 PRS_PLINK_5e.04 571 Chronic liver disease and cirrhosis Both 9 33 10 digestive chartreuse4 33, 9 9, 3 8, 2 8, 2 8, 2 0.301 0.48 0.531 0.275 1.35 0.539 3.6 0.396 1.44 0.784 0.106 1.49 0.0618 28.6 0.407 1.44 0.778 0.109 1.5 0.0875 33.6 1.27 2.29 0.578 0.238 3.57 0.0655 592 PRS_PLINK_5e.04 571.5 Other chronic nonalcoholic liver disease Both 9 34 10 digestive chartreuse4 34, 9 9, 3 8, 2 8, 2 9, 2 0.328 0.481 0.495 0.305 1.39 0.553 3.74 0.197 1.26 0.876 0.058 1.22 0.0783 15.8 0.333 1.38 0.809 0.092 1.4 0.0875 27.5 0.891 1.79 0.619 0.208 2.44 0.0961 519 PRS_PLINK_5e.04 571.51 Cirrhosis of liver without mention of alcohol Both 0 14 10 digestive chartreuse4 14, 0 4 3 3 4 PRS_PLINK_5e.04 571.6 Primary biliary cirrhosis Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_5e.04 571.8 Liver abscess and sequelae of chronic liver disease Both 1 12 10 digestive chartreuse4 12, 1 3, 0 3, 0 3, 1 3, 0 0.0268 1.42 0.985 0.007 1.03 0.0353 53.4 -0.333 164 0.998 0.001 0.717 0.0869 1.16 PRS_PLINK_5e.04 571.81 Portal hypertension Both 1 8 10 digestive chartreuse4 8, 1 2, 0 2, 0 2, 1 2, 0 1.27e-13 11.1 1 0 1 0.979 3.86 -0.505 2220 1 0 0.603 0.0284 4.35 PRS_PLINK_5e.04 572 Ascites (non malignant) Both 1 23 10 digestive chartreuse4 23, 1 6, 0 6, 0 5, 1 6, 0 -0.0167 0.609 0.978 0.01 0.983 0.0795 3.05 0.787 2.56 0.759 0.12 2.2 0.00415 1270 PRS_PLINK_5e.04 573 Other disorders of liver Both 7 38 10 digestive chartreuse4 38, 7 10, 3 9, 1 9, 1 10, 2 0.413 0.494 0.403 0.394 1.51 0.569 4.46 -0.33 1.19 0.781 0.107 0.719 0.078 5.77 -0.255 1.63 0.876 0.058 0.775 0.000468 44.7 -0.427 1.45 0.767 0.115 0.652 0.0275 9.24 PRS_PLINK_5e.04 573.1 Chronic passive congestion of liver Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_5e.04 573.2 Liver replaced by transplant Both 0 6 10 digestive chartreuse4 6, 0 2 1 1 2 PRS_PLINK_5e.04 573.3 Hepatomegaly Both 1 5 10 digestive chartreuse4 5, 1 2, 0 1, 0 1, 0 1, 1 0.0827 8460000 1 0 1.09 0.179 1.54 -0.176 4740 1 0 0.838 0.215 1.61 PRS_PLINK_5e.04 573.4 Acute and subacute necrosis of liver Both 0 3 10 digestive chartreuse4 3, 0 1 1 1 1 PRS_PLINK_5e.04 573.5 Jaundice (not of newborn) Both 2 13 10 digestive chartreuse4 13, 2 4, 2 3, 0 3, 0 3, 0 -0.927 1.77 0.6 0.222 0.396 0.000525 6.85 0.394 21.3 0.985 0.006 1.48 1.44 1.52 2.64 74.1 0.972 0.013 14.1 47.2 85.1 -1.44 181 0.994 0.003 0.238 0.00628 0.0264 PRS_PLINK_5e.04 573.6 Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH] Both 7 31 10 digestive chartreuse4 31, 7 7, 2 8, 4 7, 1 8, 0 -0.47 0.519 0.365 0.438 0.625 0.191 1.53 0.0391 1.34 0.977 0.01 1.04 0.0772 12.3 -0.731 2.33 0.754 0.123 0.482 0.00387 30 -1.36 1.78 0.446 0.35 0.258 0.000192 3.49 PRS_PLINK_5e.04 573.7 Abnormal results of function study of liver Both 7 30 10 digestive chartreuse4 30, 7 7, 1 7, 4 7, 1 8, 1 0.224 0.491 0.648 0.188 1.25 0.498 3.22 2.34 1.92 0.221 0.655 10.4 0.521 27800 1.01 2.22 0.647 0.189 2.76 0.00272 14000 -0.212 2.02 0.916 0.038 0.809 0.0265 27.7 PRS_PLINK_5e.04 573.9 Abnormal serum enzyme levels Both 13 39 10 digestive chartreuse4 39, 13 9, 3 10, 3 9, 5 10, 2 -0.341 0.42 0.416 0.38 0.711 0.297 1.48 0.464 1.26 0.712 0.148 1.59 0.16 17.5 -0.181 1.09 0.867 0.062 0.834 0.0359 5.47 -1.4 1.39 0.315 0.502 0.248 0.00217 2.4 PRS_PLINK_5e.04 574 Cholelithiasis and cholecystitis Both 1 45 10 digestive chartreuse4 45, 1 12, 0 11, 0 11, 0 11, 1 0.629 0.598 0.294 0.532 1.87 0.498 17.4 0.789 1.4 0.573 0.241 2.2 0.171 88.9 PRS_PLINK_5e.04 574.1 Cholelithiasis Both 1 43 10 digestive chartreuse4 43, 1 11, 0 11, 0 10, 0 11, 1 0.659 0.616 0.285 0.545 1.93 0.513 60 0.876 1.49 0.557 0.254 2.4 0.176 210 PRS_PLINK_5e.04 574.11 Cholelithiasis with acute cholecystitis Both 0 6 10 digestive chartreuse4 6, 0 2 1 1 2 PRS_PLINK_5e.04 574.12 Cholelithiasis with other cholecystitis Both 0 14 10 digestive chartreuse4 14, 0 3 3 3 4 PRS_PLINK_5e.04 574.2 Calculus of bile duct Both 0 11 10 digestive chartreuse4 11, 0 3 3 2 3 PRS_PLINK_5e.04 574.3 Cholecystitis without cholelithiasis Both 0 14 10 digestive chartreuse4 14, 0 4 3 3 4 PRS_PLINK_5e.04 575 Other biliary tract disease Both 0 33 10 digestive chartreuse4 33, 0 9 8 8 8 PRS_PLINK_5e.04 575.1 Cholangitis Both 0 1 10 digestive chartreuse4 1, 0 PRS_PLINK_5e.04 575.2 Obstruction of bile duct Both 0 5 10 digestive chartreuse4 5, 0 2 1 1 1 PRS_PLINK_5e.04 575.6 Cholesterolosis of gallbladder Both 0 5 10 digestive chartreuse4 5, 0 2 1 1 1 PRS_PLINK_5e.04 575.7 Other disorders of gallbladder Both 0 12 10 digestive chartreuse4 12, 0 3 3 3 3 PRS_PLINK_5e.04 575.8 Other disorders of biliary tract Both 0 12 10 digestive chartreuse4 12, 0 3 3 3 3 PRS_PLINK_5e.04 577 Diseases of pancreas Both 3 31 10 digestive chartreuse4 31, 3 8, 3 8, 0 7, 0 8, 0 -0.826 0.901 0.36 0.444 0.438 0.0106 4.15 -0.769 1.72 0.654 0.184 0.463 0.000444 13.2 -1.15 2.68 0.667 0.176 0.315 0.000352 92.4 -1.2 2.27 0.597 0.224 0.301 6.29e-05 35.1 PRS_PLINK_5e.04 577.1 Acute pancreatitis Both 1 19 10 digestive chartreuse4 19, 1 5, 1 5, 0 4, 0 5, 0 -0.616 0.871 0.48 0.319 0.54 0.0367 2.34 0.0265 108 1 0 1.03 0.906 1.79 -1.27 21.4 0.953 0.021 0.281 3.71e-07 0.348 -0.941 6.46 0.884 0.053 0.39 4.92e-05 12300 PRS_PLINK_5e.04 577.2 Chronic pancreatitis Both 0 3 10 digestive chartreuse4 3, 0 1 1 1 1 PRS_PLINK_5e.04 577.3 Cyst and pseudocyst of pancreas Both 0 4 10 digestive chartreuse4 4, 0 1 1 1 1 PRS_PLINK_5e.04 578 Gastrointestinal hemorrhage Both 13 46 10 digestive chartreuse4 46, 13 11, 2 11, 3 11, 6 12, 2 -0.0513 0.333 0.878 0.057 0.95 0.493 1.73 0.659 1.14 0.563 0.25 1.93 0.286 22.7 0.549 1.07 0.607 0.217 1.73 0.173 13.5 -0.339 1.1 0.757 0.121 0.712 0.0265 5.19 PRS_PLINK_5e.04 578.1 Hematemesis Both 4 5 10 digestive chartreuse4 5, 4 2, 1 1, 3 1, 0 1, 0 0.188 102 0.999 0.001 1.21 0.324 7.39 0.106 60.2 0.999 0.001 1.11 0.789 1.41 0.469 3720 1 0 1.6 0.395 3.12 0.969 6620 1 0 2.64 0.143 92.7 PRS_PLINK_5e.04 578.2 Blood in stool Both 7 33 10 digestive chartreuse4 33, 7 8, 1 8, 3 8, 2 8, 1 -0.116 0.461 0.802 0.096 0.891 0.346 2.05 -0.459 1.49 0.758 0.12 0.632 0.0372 10.3 -0.967 1.93 0.617 0.21 0.38 0.00218 35.1 -0.0285 1.5 0.985 0.007 0.972 7.02e-05 65.6 PRS_PLINK_5e.04 578.8 Hemorrhage of rectum and anus Both 7 31 10 digestive chartreuse4 31, 7 8, 1 8, 2 7, 3 8, 1 0.103 0.547 0.851 0.07 1.11 0.37 3.26 -0.113 1.8 0.95 0.022 0.893 0.000861 69.5 0.331 1.5 0.826 0.083 1.39 0.0767 59.6 -0.524 2.4 0.827 0.083 0.592 4.04e-07 48.9 PRS_PLINK_5e.04 578.9 Hemorrhage of gastrointestinal tract Both 3 16 10 digestive chartreuse4 16, 3 4, 2 4, 1 4, 0 4, 0 -1.02 1.22 0.403 0.395 0.361 0.0175 4.94 -0.702 3.57 0.844 0.074 0.495 0.478 0.511 -1.33 3.62 0.713 0.147 0.263 0.000779 35.7 2.42 63.5 0.97 0.013 11.2 0.129 16.8 PRS_PLINK_5e.04 579 Other symptoms involving abdomen and pelvis Both 6 41 10 digestive chartreuse4 41, 6 11, 1 10, 2 10, 2 10, 1 -0.168 0.442 0.704 0.152 0.845 0.311 2.01 0.118 1.28 0.927 0.033 1.13 0.114 15.4 0.263 1.25 0.834 0.079 1.3 0.101 18.7 0.0584 1.38 0.966 0.015 1.06 0.0405 104 PRS_PLINK_5e.04 579.2 Splenomegaly Both 1 9 10 digestive chartreuse4 9, 1 3, 0 2, 0 2, 0 2, 1 0.0336 3.9 0.993 0.003 1.03 0.0166 49.6 0.0184 8170000 1 0 1.02 1.07e-06 306000 PRS_PLINK_5e.04 579.8 Nonspecific abnormal findings in stool contents Both 2 19 10 digestive chartreuse4 19, 2 5, 0 5, 0 4, 2 5, 0 -0.18 1.18 0.879 0.056 0.835 0.048 17.8 -0.00742 2.45 0.998 0.001 0.993 0.0033 86.9 PRS_PLINK_5e.04 580 Nephritis; nephrosis; renal sclerosis Both 15 11 11 genitourinary black 11, 15 3, 9 3, 1 2, 0 3, 4 -0.496 0.707 0.482 0.317 0.609 0.0948 2.12 -1.12 1.56 0.473 0.325 0.326 1.28e-06 3.33 -3.43 3.54 0.333 0.477 0.0325 5.6e-05 4.85 -0.898 2.19 0.681 0.167 0.407 0.00052 173 PRS_PLINK_5e.04 580.1 Glomerulonephritis Both 2 4 11 genitourinary black 4, 2 1, 1 1, 1 1, 0 1, 0 -0.127 869 1 0 0.881 0.366 1.51 0.0241 3540 1 0 1.02 0.477 1.49 -0.00712 65 1 0 0.993 0.902 1.21 0.0144 121 1 0 1.01 0.889 1.19 PRS_PLINK_5e.04 580.11 Proliferative glomerulonephritis Both 1 1 11 genitourinary black 1, 1 0.00115 115 1 0 1 0.977 1.02 PRS_PLINK_5e.04 580.12 Non-proliferative glomerulonephritis Both 0 1 11 genitourinary black 1, 0 PRS_PLINK_5e.04 580.13 Acute glomerulonephritis, NOS Both 1 1 11 genitourinary black 1, 1 -0.0047 31 1 0 0.995 0.91 1.1 PRS_PLINK_5e.04 580.14 Chronic glomerulonephritis, NOS Both 0 2 11 genitourinary black 2, 0 1 1 1 1 PRS_PLINK_5e.04 580.2 Nephrotic syndrome without mention of glomerulonephritis Both 0 3 11 genitourinary black 3, 0 1 1 1 1 PRS_PLINK_5e.04 580.3 Nephritis and nephropathy without mention of glomerulonephritis Both 13 11 11 genitourinary black 11, 13 3, 8 3, 0 2, 0 3, 4 -0.497 0.722 0.491 0.309 0.608 0.102 2.4 -1.8 2.29 0.433 0.363 0.166 0.00358 4.02 -2.12 3.33 0.524 0.281 0.12 0.0968 7.5 0.134 2.41 0.956 0.02 1.14 0.000835 387 PRS_PLINK_5e.04 580.31 Nephritis and nephropathy in diseases classified elsewhere Both 11 9 11 genitourinary black 9, 11 3, 7 2, 0 2, 0 2, 3 -0.405 0.75 0.589 0.23 0.667 0.112 2.55 -3.05 5.03 0.544 0.264 0.0471 0.000222 11.7 -2.12 4.85 0.662 0.179 0.12 5.15e-05 93.4 -0.0406 2.39 0.986 0.006 0.96 0.0207 53.1 PRS_PLINK_5e.04 580.32 Nephritis and nephropathy with pathological lesion Both 3 7 11 genitourinary black 7, 3 2, 2 2, 0 1, 0 2, 1 -1.5 7.5 0.842 0.075 0.223 0.211 0.235 -0.0536 539 1 0 0.948 0.583 1.18 -0.083 14300 1 0 0.92 0.645 13.2 -0.333 1030000 1 0 0.717 0.109 4.91 PRS_PLINK_5e.04 580.4 Renal sclerosis, NOS Both 1 3 11 genitourinary black 3, 1 1, 1 1, 0 1, 0 1, 1 0.158 3600 1 0 1.17 0.368 1.27 -0.039 1740 1 0 0.962 0.693 1.12 0.219 4930 1 0 1.24 0.431 4.72 PRS_PLINK_5e.04 585 Renal failure Both 24 16 11 genitourinary black 16, 24 4, 14 4, 5 4, 0 4, 5 -0.917 0.567 0.106 0.975 0.4 0.124 1.09 -0.965 1.15 0.401 0.396 0.381 0.0368 4.76 -3.91 2.25 0.0831 1.081 0.0201 1.24e-05 0.582 -1.32 1.56 0.397 0.401 0.268 0.00462 4.5 PRS_PLINK_5e.04 585.1 Acute renal failure Both 8 14 11 genitourinary black 14, 8 4, 6 3, 2 3, 0 4, 0 -2.02 1.25 0.107 0.97 0.133 0.119 0.766 -1.18 1.63 0.466 0.331 0.306 0.275 2.89 -2.08 4 0.603 0.219 0.125 0.113 10 -2.24 5.37 0.676 0.17 0.106 0.0926 0.12 PRS_PLINK_5e.04 585.2 Renal failure NOS Both 4 6 11 genitourinary black 6, 4 2, 0 1, 2 1, 1 2, 1 0.304 1.41 0.829 0.081 1.36 0.285 1.42 0.212 1110000 1 0 1.24 0.342 1.93 -1.28 20800 1 0 0.278 8.96e-07 12100 0.0629 823 1 0 1.06 0.904 1.52 PRS_PLINK_5e.04 585.3 Chronic renal failure [CKD] Both 17 15 11 genitourinary black 15, 17 4, 9 4, 3 3, 0 4, 5 -0.43 0.784 0.583 0.234 0.651 0.111 3.04 -1.79 2.16 0.409 0.389 0.168 0.00138 6.67 -2.01 3.44 0.559 0.253 0.134 5.54e-05 50.3 -0.0855 1.76 0.961 0.017 0.918 0.0286 40.6 PRS_PLINK_5e.04 585.31 Renal dialysis Both 0 5 11 genitourinary black 5, 0 2 1 1 1 PRS_PLINK_5e.04 585.32 End stage renal disease Both 1 9 11 genitourinary black 9, 1 3, 1 2, 0 2, 0 2, 0 0.115 1.88 0.951 0.022 1.12 0.0617 39.7 0.0281 1880 1 0 1.03 0.366 2.99 -0.0213 176 1 0 0.979 0.738 1.25 -0.0404 517 1 0 0.96 0.646 1.39 PRS_PLINK_5e.04 585.33 Chronic Kidney Disease, Stage III Both 7 11 11 genitourinary black 11, 7 3, 3 3, 2 2, 0 3, 2 -0.0561 1.23 0.963 0.016 0.945 0.0851 23.2 3.8 12.2 0.755 0.122 44.7 34 57.7 0.0283 40.1 0.999 0 1.03 17.5 7.1 2.67 20.4 0.896 0.048 14.5 11.9 17.4 PRS_PLINK_5e.04 585.34 Chronic Kidney Disease, Stage IV Both 0 10 11 genitourinary black 10, 0 3 2 2 3 PRS_PLINK_5e.04 585.4 Chronic kidney disease, Stage I or II Both 10 10 11 genitourinary black 10, 10 3, 6 2, 1 2, 0 3, 3 0.0686 1.16 0.953 0.021 1.07 0.15 63 0.619 4.09 0.88 0.056 1.86 0.0024 2.38 1.69 7.74 0.827 0.082 5.42 4.91 6.06 -0.626 3.93 0.873 0.059 0.534 5.71e-07 10700 PRS_PLINK_5e.04 586 Other disorders of the kidney and ureters Both 37 17 11 genitourinary black 17, 37 5, 19 4, 8 4, 1 4, 8 -0.694 0.38 0.0679 1.168 0.5 0.222 0.976 -1 0.933 0.283 0.549 0.367 0.0558 1.96 -2.89 1.67 0.0828 1.082 0.0554 0.000285 0.801 -0.167 0.919 0.856 0.068 0.846 0.164 4.64 PRS_PLINK_5e.04 586.1 Anatomical abnormatilies of kidney and ureters Both 2 2 11 genitourinary black 2, 2 1, 2 1, 0 1, 2 1, 0 -0.268 4620 1 0 0.765 0.062 7.15 0.607 3600 1 0 1.83 0.34 90.8 PRS_PLINK_5e.04 586.11 Small kidney Both 1 0 11 genitourinary black 0, 1 PRS_PLINK_5e.04 586.12 Vesicoureteral reflux Both 2 1 11 genitourinary black 1, 2 2.57e-05 10200 1 0 1 0.106 8.94 PRS_PLINK_5e.04 586.2 Cyst of kidney, acquired Both 2 6 11 genitourinary black 6, 2 2, 1 1, 1 1, 0 2, 0 0.874 22900000 1 0 2.4 0.0584 491000 0.123 1370 1 0 1.13 0.875 2.03 2.75 31500 1 0 15.6 5.84e-13 3.73e+13 0.778 16800000 1 0 2.18 0.000127 226000 PRS_PLINK_5e.04 586.3 Vascular disorders of kidney/hypertrophy Both 0 1 11 genitourinary black 1, 0 PRS_PLINK_5e.04 586.4 Stricture/obstruction of ureter Both 3 6 11 genitourinary black 6, 3 2, 1 1, 1 1, 0 2, 1 0.501 8.11 0.951 0.022 1.65 1.63 3.66 0.534 6050 1 0 1.71 0.768 2.17 0.683 15600 1 0 1.98 0.233 119 0.00128 678 1 0 1 0.739 1.17 PRS_PLINK_5e.04 587 Kidney replaced by transpant Both 1 8 11 genitourinary black 8, 1 2, 0 2, 0 2, 0 2, 1 -0.0471 20.8 0.998 0.001 0.954 0.018 51.8 -0.574 1.48e+08 1 0 0.563 1.61e-05 5 PRS_PLINK_5e.04 588 Disorders resulting from impaired renal function Both 2 10 11 genitourinary black 10, 2 3, 1 2, 0 2, 0 3, 1 0.279 1.68 0.868 0.061 1.32 0.115 62.4 0.0315 8610 1 0 1.03 0.294 1.05 0.0621 1160 1 0 1.06 0.509 3.42 0.763 492 0.999 0.001 2.15 7.29 13.5 PRS_PLINK_5e.04 588.1 Renal osteodystrophy Both 0 5 11 genitourinary black 5, 0 2 1 1 1 PRS_PLINK_5e.04 588.2 Secondary hyperparathyroidism (of renal origin) Both 2 8 11 genitourinary black 8, 2 2, 1 2, 0 2, 0 2, 1 -0.144 1.8 0.936 0.029 0.866 0.822 0.93 -1.9 18800000 1 0 0.149 3.23e-05 282 -0.332 2300 1 0 0.718 0.689 1.49 -0.0894 1780 1 0 0.915 0.668 3.1 PRS_PLINK_5e.04 589 Abnormal results of function study of kidney Both 5 8 11 genitourinary black 8, 5 2, 0 2, 3 2, 1 2, 1 1.02 2.03 0.616 0.21 2.77 0.127 3.03 -0.242 1610 1 0 0.785 0.229 1.35 0.00831 1300 1 0 1.01 0.751 1.38 -9.67 6850 0.999 0 6.32e-05 5.39e-16 11200000 PRS_PLINK_5e.04 590 Pyelonephritis Both 4 8 11 genitourinary black 8, 4 2, 0 2, 3 2, 1 2, 0 -0.76 3.17 0.81 0.091 0.468 0.44 0.503 0.0768 1450 1 0 1.08 0.623 1.13 0.0313 4170000 1 0 1.03 0.346 2.48 PRS_PLINK_5e.04 591 Urinary tract infection Both 25 31 11 genitourinary black 31, 25 8, 1 8, 8 7, 9 8, 7 0.389 0.375 0.299 0.524 1.48 0.744 3.1 2.75 1.6 0.0853 1.069 15.6 1.01 12600 2.62 1.55 0.0903 1.044 13.7 1.26 86300 1.13 1.32 0.392 0.407 3.09 0.353 67.5 PRS_PLINK_5e.04 592 Cystitis and urethritis Both 9 15 11 genitourinary black 15, 9 4, 0 4, 2 3, 0 4, 7 0.548 0.69 0.427 0.369 1.73 0.44 7.61 1.93 6.57 0.769 0.114 6.92 0.000241 220000 3.48 2.66 0.192 0.717 32.3 0.676 7120 PRS_PLINK_5e.04 592.1 Cystitis Both 9 14 11 genitourinary black 14, 9 4, 0 3, 2 3, 0 4, 7 0.534 0.692 0.441 0.356 1.71 0.469 8.85 1.36 26.9 0.96 0.018 3.88 12.9 11 3.48 2.66 0.192 0.717 32.3 0.676 7120 PRS_PLINK_5e.04 592.11 Acute cystitis Both 6 10 11 genitourinary black 10, 6 3, 0 2, 2 2, 0 3, 4 0.12 1.62 0.941 0.026 1.13 0.0661 17 -0.00269 651 1 0 0.997 0.322 2.98 0.509 430 0.999 0 1.66 0.117 0.658 PRS_PLINK_5e.04 592.12 Chronic cystitis Both 2 3 11 genitourinary black 3, 2 1, 0 1, 1 1, 1 1, 0 -0.311 1830 1 0 0.733 0.202 3.11 -0.00728 71.5 1 0 0.993 0.936 1.06 -0.0205 47.3 1 0 0.98 0.953 1.04 PRS_PLINK_5e.04 592.13 Chronic interstitial cystitis Both 1 7 11 genitourinary black 7, 1 2, 0 2, 0 1, 0 2, 1 -0.0611 2010 1 0 0.941 0.534 1.87 -0.265 13300 1 0 0.767 0.068 2.86 PRS_PLINK_5e.04 592.2 Urethritis and urethral syndrome Both 2 1 11 genitourinary black 1, 2 0.22 17.1 0.99 0.005 1.25 0.732 1.38 PRS_PLINK_5e.04 593 Hematuria Both 17 29 11 genitourinary black 29, 17 8, 3 7, 4 7, 4 7, 6 0.442 0.403 0.272 0.565 1.56 0.765 3.47 2.16 1.55 0.165 0.783 8.64 0.98 10.6 3.37 2.2 0.125 0.902 29.1 1.15 1.42e+08 0.985 1.22 0.418 0.379 2.68 0.369 184 PRS_PLINK_5e.04 593.1 Gross hematuria Both 6 16 11 genitourinary black 16, 6 4, 0 4, 1 4, 1 4, 4 0.305 0.701 0.663 0.178 1.36 0.278 8.74 -0.387 38.4 0.992 0.004 0.679 0.15 3.52 0.195 20.2 0.992 0.003 1.22 0.437 4.01 1.35 3.02 0.655 0.184 3.86 0.101 184 PRS_PLINK_5e.04 593.2 Microscopic hematuria Both 6 9 11 genitourinary black 9, 6 3, 3 2, 0 2, 1 2, 2 -0.934 1.17 0.427 0.37 0.393 0.00169 2.05 -0.47 2380 1 0 0.625 0.0793 0.16 0.0421 1250 1 0 1.04 0.00871 1.94 -1.47 4.51 0.745 0.128 0.23 0.217 0.239 PRS_PLINK_5e.04 594 Urinary calculus Both 13 43 11 genitourinary black 43, 13 11, 7 11, 0 10, 4 11, 2 -0.824 0.503 0.101 0.994 0.439 0.136 1.1 -5.31 3.21 0.0984 1.007 0.00496 0.00352 0.843 -0.694 1.12 0.536 0.271 0.499 0.043 3.81 -2.58 1.75 0.14 0.853 0.0759 6.7e-05 2.81 PRS_PLINK_5e.04 594.1 Calculus of kidney Both 13 43 11 genitourinary black 43, 13 11, 7 11, 0 10, 4 11, 2 -0.824 0.503 0.101 0.994 0.439 0.136 1.1 -5.31 3.21 0.0984 1.007 0.00496 0.00352 0.843 -0.694 1.12 0.536 0.271 0.499 0.043 3.81 -2.58 1.75 0.14 0.853 0.0759 6.7e-05 2.81 PRS_PLINK_5e.04 594.2 Calculus of lower urinary tract Both 1 4 11 genitourinary black 4, 1 1, 0 1, 0 1, 0 1, 1 -9.05 83600000 1 0 0.000118 3.08e-16 16800000 -0.188 4560 1 0 0.829 0.685 1.45 PRS_PLINK_5e.04 594.3 Calculus of ureter Both 2 17 11 genitourinary black 17, 2 5, 2 4, 0 4, 0 4, 0 -0.133 0.859 0.877 0.057 0.876 0.0335 5.15 -0.789 2.16 0.715 0.145 0.454 0.415 0.535 0.503 2.49 0.84 0.076 1.65 0.0373 77.2 1.36 5.32 0.798 0.098 3.9 0.00181 2.93e+10 PRS_PLINK_5e.04 594.8 Renal colic Both 1 5 11 genitourinary black 5, 1 2, 0 1, 0 1, 1 1, 0 -0.0163 511 1 0 0.984 0.522 1.38 -0.0493 1410 1 0 0.952 1.26e-06 53.6 PRS_PLINK_5e.04 595 Hydronephrosis Both 4 15 11 genitourinary black 15, 4 4, 1 4, 0 3, 2 4, 1 -0.969 0.989 0.327 0.485 0.379 0.00759 1.82 -1.03 1540 0.999 0 0.358 0.000127 8260 -2.21 255 0.993 0.003 0.109 0.011 0.00446 -0.529 37.4 0.989 0.005 0.589 0.549 1610 PRS_PLINK_5e.04 596 Other disorders of bladder Both 5 25 11 genitourinary black 25, 5 7, 2 6, 0 6, 2 6, 1 0.0114 0.695 0.987 0.006 1.01 0.242 4.28 -0.615 2.22 0.782 0.107 0.541 0.00264 21.4 0.245 1.72 0.887 0.052 1.28 0.0816 71 1.11 2.75 0.687 0.163 3.02 0.0164 2400000 PRS_PLINK_5e.04 596.1 Bladder neck obstruction Both 1 2 11 genitourinary black 2, 1 1, 0 0, 1 1, 0 1, 0 0.0923 2300 1 0 1.1 0.747 2.41 -0.0128 47.4 1 0 0.987 0.825 9.96 PRS_PLINK_5e.04 596.5 Functional disorders of bladder Both 5 16 11 genitourinary black 16, 5 4, 2 4, 1 4, 2 4, 0 -0.982 1.19 0.409 0.388 0.375 0.000123 2.79 -1.76 2.84 0.534 0.272 0.171 0.00103 6.5 -0.565 3.08 0.854 0.068 0.568 0.00256 86.5 0.313 388 0.999 0 1.37 0.663 1.42 PRS_PLINK_5e.04 597 Other disorders of urethra and urinary tract Both 3 7 11 genitourinary black 7, 3 2, 0 2, 1 1, 1 2, 1 0.0348 1.25 0.978 0.01 1.04 0.153 6.29 2.12 18900 1 0 8.32 0.959 4.02e+09 -3.94 343000 1 0 0.0194 2.43e-07 534 -0.293 8760 1 0 0.746 0.432 3.53 PRS_PLINK_5e.04 597.1 Urethral stricture (not specified as infectious) Both 2 2 11 genitourinary black 2, 2 1, 0 1, 2 1, 0 1, 2 -0.0801 2920 1 0 0.923 0.303 1.58 -0.204 9150 1 0 0.815 0.0643 2.67 PRS_PLINK_5e.04 597.2 Urinary complications NEC Both 1 8 11 genitourinary black 8, 1 2, 0 2, 0 2, 0 2, 1 -0.115 5.77 0.984 0.007 0.891 0.305 2.54 -2.17 6740000 1 0 0.114 1.42e-05 1110 PRS_PLINK_5e.04 597.8 Urethral hypermobility/ISD Both 0 2 11 genitourinary black 2, 0 1 1 1 1 PRS_PLINK_5e.04 598 Abnormal findings on examination of urine Both 0 2 11 genitourinary black 2, 0 1 1 1 1 PRS_PLINK_5e.04 598.4 Other cells and casts in urine Both 0 2 11 genitourinary black 2, 0 1 1 1 1 PRS_PLINK_5e.04 599 Other symptoms/disorders or the urinary system Both 25 35 11 genitourinary black 35, 25 8, 2 9, 5 8, 9 9, 9 0.547 0.341 0.108 0.967 1.73 0.942 3.43 0.278 1.26 0.824 0.084 1.32 0.108 14.6 2.43 1.33 0.0676 1.17 11.4 1.38 9250 1.57 1.14 0.167 0.776 4.79 0.782 53.2 PRS_PLINK_5e.04 599.1 Urinary obstruction Both 3 6 11 genitourinary black 6, 3 2, 1 1, 0 1, 0 2, 2 0.439 15.5 0.977 0.01 1.55 0.826 3.29 -0.0958 772 1 0 0.909 0.896 1.08 0.00497 1710 1 0 1 0.883 1.3 0.17 69.1 0.998 0.001 1.18 0.162 3.5 PRS_PLINK_5e.04 599.2 Retention of urine Both 11 27 11 genitourinary black 27, 11 7, 1 7, 4 6, 2 7, 4 0.272 0.477 0.569 0.245 1.31 0.581 3.17 2.15 2.09 0.304 0.517 8.55 0.28 4610 1.13 1.88 0.547 0.262 3.1 0.0191 139000 2.21 1.82 0.224 0.65 9.11 0.572 5140 PRS_PLINK_5e.04 599.3 Dysuria Both 13 27 11 genitourinary black 27, 13 7, 2 7, 2 6, 4 7, 5 0.568 0.452 0.209 0.679 1.76 0.811 4.16 0.371 1.56 0.812 0.09 1.45 0.0694 1.64 0.68 1.41 0.63 0.2 1.97 0.139 40.8 -0.108 1.35 0.936 0.029 0.898 0.00754 9.8 PRS_PLINK_5e.04 599.4 Urinary incontinence Both 6 24 11 genitourinary black 24, 6 6, 0 6, 1 6, 3 6, 2 -0.0873 0.733 0.905 0.043 0.916 0.00873 3.69 0.638 1.85 0.73 0.137 1.89 0.0656 249 1.08 2 0.588 0.231 2.95 0.0539 1390 0.319 1.55 0.837 0.077 1.38 0.0773 22.8 PRS_PLINK_5e.04 599.5 Frequency of urination and polyuria Both 10 31 11 genitourinary black 31, 10 8, 0 8, 2 7, 5 8, 3 0.656 0.548 0.231 0.636 1.93 0.689 6.17 1.01 1.96 0.607 0.217 2.74 0.0265 33600 2.64 1.73 0.127 0.897 14 1.18 1.1e+08 0.6 1.42 0.673 0.172 1.82 0.0663 61 PRS_PLINK_5e.04 599.6 Oliguria and anuria Both 1 10 11 genitourinary black 10, 1 3, 1 2, 0 2, 0 3, 0 0.528 2.13 0.804 0.095 1.7 1.62 1.77 0.505 3420 1 0 1.66 0.237 2.68 0.102 701 1 0 1.11 0.691 2.02 -0.0298 162 1 0 0.971 0.859 1.07 PRS_PLINK_5e.04 599.7 Urethral discharge Both 0 6 11 genitourinary black 6, 0 2 1 1 2 PRS_PLINK_5e.04 599.8 Other symptoms involving urinary system Both 12 28 11 genitourinary black 28, 12 7, 0 7, 2 7, 5 7, 5 0.262 0.509 0.607 0.217 1.3 0.515 3.41 1.35 2.14 0.527 0.278 3.86 0.0857 184 2.47 1.7 0.147 0.832 11.8 1 899 0.287 1.6 0.858 0.067 1.33 0.0439 52.9 PRS_PLINK_5e.04 599.9 Other abnormality of urination Both 5 21 11 genitourinary black 21, 5 6, 0 5, 0 5, 3 5, 2 0.767 0.708 0.279 0.555 2.15 0.699 14.2 1.88 2.22 0.398 0.401 6.54 0.0849 3980 0.0425 2.37 0.986 0.006 1.04 0.0201 179 PRS_PLINK_5e.04 600 Hyperplasia of prostate Male 3 16 11 genitourinary black 16, 3 4, 1 4, 0 4, 1 4, 1 0.455 0.81 0.575 0.241 1.58 0.00563 9.89 -0.201 2.37 0.932 0.03 0.818 0.799 0.925 4.97 19.1 0.795 0.1 144 2.12e-06 6.34e+09 1.53 8.4 0.855 0.068 4.62 4.21 5.08 PRS_PLINK_5e.04 601 Inflammatory diseases of prostate Male 3 13 11 genitourinary black 13, 3 4, 0 3, 2 3, 0 3, 1 0.391 0.81 0.629 0.201 1.48 0.365 7.37 0.288 13.8 0.983 0.007 1.33 1.28 4.32 -1.38 30.5 0.964 0.016 0.252 0.231 79.3 PRS_PLINK_5e.04 601.1 Prostatitis Male 3 5 11 genitourinary black 5, 3 2, 0 1, 2 1, 0 1, 1 -0.12 1450000 1 0 0.887 0.189 6.93 -0.113 10800 1 0 0.894 0.223 2.02 -0.00738 179 1 0 0.993 0.287 1.21 PRS_PLINK_5e.04 601.11 Acute prostatitis Male 1 1 11 genitourinary black 1, 1 -0.0345 76 1 0 0.966 0.905 1.08 PRS_PLINK_5e.04 601.12 Chronic prostatitis Male 0 1 11 genitourinary black 1, 0 PRS_PLINK_5e.04 601.3 Orchitis and epididymitis Male 0 4 11 genitourinary black 4, 0 1 1 1 1 PRS_PLINK_5e.04 601.4 Balanoposthitis Male 0 3 11 genitourinary black 3, 0 1 1 1 1 PRS_PLINK_5e.04 602 Other disorders of prostate Male 1 3 11 genitourinary black 3, 1 1, 1 1, 0 1, 0 1, 1 -0.0883 1360 1 0 0.916 0.377 1.42 0.0611 3550 1 0 1.06 0.797 2.22 -0.23 9740 1 0 0.794 0.0442 3 PRS_PLINK_5e.04 602.3 Dysplasia of prostate Male 0 1 11 genitourinary black 1, 0 PRS_PLINK_5e.04 603 Other disorders of testis Male 0 7 11 genitourinary black 7, 0 2 2 1 2 PRS_PLINK_5e.04 603.1 Hydrocele Male 0 4 11 genitourinary black 4, 0 1 1 1 1 PRS_PLINK_5e.04 603.2 Spermatocele Male 0 5 11 genitourinary black 5, 0 1 1 1 1 PRS_PLINK_5e.04 604 Disorders of penis Male 2 6 11 genitourinary black 6, 2 2, 1 1, 0 1, 0 2, 1 -0.912 100 0.993 0.003 0.402 0.151 0.105 0.0985 3130 1 0 1.1 0.654 3.24 -0.287 5040 1 0 0.751 0.0418 2.04 -0.00128 1920 1 0 0.999 0.405 2.6 PRS_PLINK_5e.04 604.3 Peyronie's disease Male 1 1 11 genitourinary black 1, 1 -0.00717 93 1 0 0.993 0.862 1.12 PRS_PLINK_5e.04 605 Erectile dysfunction [ED] Male 12 11 11 genitourinary black 11, 12 2, 3 3, 4 2, 2 3, 3 0.129 0.6 0.83 0.081 1.14 0.391 3.86 -1.03 2 0.607 0.216 0.357 1.32e-05 16.5 -0.144 2.7 0.957 0.019 0.866 0.011 97.4 -2.15 3.92 0.584 0.233 0.117 0.103 0.131 PRS_PLINK_5e.04 608 Other disorders of male genital organs Male 3 14 11 genitourinary black 14, 3 4, 0 3, 0 3, 1 4, 2 1.5 1.03 0.145 0.838 4.47 0.844 235 6.59 609 0.991 0.004 729 2.24e-07 57300000 1.72 2.55 0.5 0.301 5.57 0.162 2830 PRS_PLINK_5e.04 609 Male infertility and abnormal spermatozoa Male 2 5 11 genitourinary black 5, 2 2, 0 1, 0 1, 1 1, 1 0.495 5690 1 0 1.64 0.804 2.66 0.0235 7710 1 0 1.02 0.451 1.38 0.396 5120 1 0 1.49 0.413 8.26 PRS_PLINK_5e.04 609.1 Infertility, male Male 2 5 11 genitourinary black 5, 2 2, 0 1, 1 1, 1 1, 0 0.395 6350 1 0 1.48 0.617 1.77 -0.0116 349 1 0 0.988 0.534 1.76 0.158 1230 1 0 1.17 0.847 1.18 PRS_PLINK_5e.04 609.11 Azoospermia and oligospermia Male 1 1 11 genitourinary black 1, 1 -0.000218 15.5 1 0 1 0.982 1.01 PRS_PLINK_5e.04 609.2 Abnormal spermatozoa Male 0 2 11 genitourinary black 2, 0 1 1 1 1 PRS_PLINK_5e.04 610 Benign mammary dysplasias Female 4 14 11 genitourinary black 14, 4 4, 0 3, 1 3, 0 4, 3 0.592 0.995 0.552 0.258 1.81 0.0362 25 1.37 7.12 0.848 0.072 3.92 3.6 4.28 0.404 2.23 0.856 0.067 1.5 0.00274 245 PRS_PLINK_5e.04 610.1 Cystic mastopathy Female 3 8 11 genitourinary black 8, 3 2, 1 2, 0 2, 0 2, 2 0.0537 1.24 0.965 0.015 1.06 0.0183 31.9 -0.0662 2750 1 0 0.936 0.409 2.14 0.383 4430000 1 0 1.47 0.862 2.32 -0.41 745 1 0 0.663 0.138 0.964 PRS_PLINK_5e.04 610.2 Fibroadenosis of breast Female 0 1 11 genitourinary black 1, 0 PRS_PLINK_5e.04 610.4 Benign neoplasm of breast Female 2 14 11 genitourinary black 14, 2 4, 0 3, 1 3, 0 4, 1 0.225 1.18 0.849 0.071 1.25 0.126 20.6 1.37 7.12 0.848 0.072 3.92 3.6 4.28 0.166 3.43 0.961 0.017 1.18 0.0102 423 PRS_PLINK_5e.04 610.8 Other specified benign mammary dysplasias Female 2 7 11 genitourinary black 7, 2 2, 1 2, 0 1, 0 2, 1 1.71 5.3 0.747 0.127 5.53 4.68 6.38 -0.167 2140 1 0 0.846 0.312 1.33 -0.0405 39.2 0.999 0 0.96 0.639 2.64 0.157 996 1 0 1.17 0.627 4.44 PRS_PLINK_5e.04 611 Abnormal findings on mammogram or breast exam Both 10 17 11 genitourinary black 17, 10 5, 0 4, 1 4, 5 4, 4 -0.18 0.957 0.851 0.07 0.835 0.0207 9.45 0.52 6.76 0.939 0.027 1.68 0.0112 434 0.624 1.84 0.735 0.134 1.87 0.0915 280 1.21 2.65 0.649 0.187 3.34 0.0685 10600 PRS_PLINK_5e.04 611.1 Abnormal mammogram Both 8 14 11 genitourinary black 14, 8 4, 0 3, 2 3, 2 4, 4 -0.835 1.34 0.532 0.274 0.434 0.0175 7.57 0.144 2.59 0.956 0.02 1.15 0.0182 57 -0.0172 55.1 1 0 0.983 0.000711 1470 1.21 2.65 0.649 0.187 3.34 0.0685 10600 PRS_PLINK_5e.04 611.11 Mammographic microcalcification Both 2 6 11 genitourinary black 6, 2 2, 0 1, 1 1, 0 2, 1 -0.745 134 0.996 0.002 0.475 0.0943 0.125 -0.0355 1210 1 0 0.965 0.917 1.11 -0.0174 652 1 0 0.983 0.0561 1.37 PRS_PLINK_5e.04 611.3 Lump or mass in breast Both 5 16 11 genitourinary black 16, 5 4, 0 4, 0 4, 2 4, 3 -0.115 0.914 0.9 0.046 0.891 0.12 14.8 1.1 3.23 0.734 0.134 3 0.0388 578 -0.727 12.5 0.954 0.021 0.483 2.93e-05 10500 PRS_PLINK_5e.04 612 Breast conditions, congenital or relating to hormones Both 2 11 11 genitourinary black 11, 2 3, 0 3, 1 2, 1 3, 0 0.798 2.41 0.74 0.13 2.22 0.0691 961 0.19 1910 1 0 1.21 0.706 1.62 0.0528 769 1 0 1.05 0.868 1.66 PRS_PLINK_5e.04 612.1 Galactorrhea Both 0 1 11 genitourinary black 1, 0 PRS_PLINK_5e.04 612.2 Hypertrophy of breast (Gynecomastia) Both 2 6 11 genitourinary black 6, 2 2, 1 1, 0 1, 1 2, 0 0.174 712 1 0 1.19 0.53 5 -0.133 4450 1 0 0.875 0.812 1.64 -0.00836 644 1 0 0.992 0.747 1.31 -0.0343 13800 1 0 0.966 0.48 3.33 PRS_PLINK_5e.04 613 Other nonmalignant breast conditions Both 9 25 11 genitourinary black 25, 9 7, 2 6, 1 6, 1 6, 5 1 0.68 0.14 0.854 2.73 0.858 15 -1.23 2.32 0.596 0.225 0.293 0.000546 11.9 0.138 2.43 0.955 0.02 1.15 0.0102 22600000 0.421 1.85 0.82 0.086 1.52 0.0693 70.5 PRS_PLINK_5e.04 613.1 Inflammatory disease of breast Both 1 4 11 genitourinary black 4, 1 1, 1 1, 0 1, 0 1, 0 0.0992 9800 1 0 1.1 0.011 32.9 0.145 86800 1 0 1.16 0.517 1.86 0.486 239000 1 0 1.63 0.0526 552 0.227 138000 1 0 1.26 0.0894 25.3 PRS_PLINK_5e.04 613.5 Mastodynia Both 3 14 11 genitourinary black 14, 3 4, 1 3, 2 3, 0 4, 0 -0.132 1.33 0.921 0.036 0.876 0.0648 11 3.32 5.71 0.561 0.251 27.7 0.0698 34 0.283 56.8 0.996 0.002 1.33 0.66 0.627 1.27 200 0.995 0.002 3.55 9.45 15.3 PRS_PLINK_5e.04 613.7 Other signs and symptoms in breast Both 4 7 11 genitourinary black 7, 4 2, 0 2, 1 1, 0 2, 3 0.813 1.63 0.618 0.209 2.26 0.0822 2.62 0.0148 2330 1 0 1.01 0.0308 161 -1.61 18300000 1 0 0.199 0.000546 200 PRS_PLINK_5e.04 613.8 Other specified disorders of breast Both 0 7 11 genitourinary black 7, 0 2 2 1 2 PRS_PLINK_5e.04 613.9 Breast disorder NOS Both 2 10 11 genitourinary black 10, 2 3, 0 2, 0 2, 0 3, 2 1.22 1.47 0.407 0.39 3.39 0.465 66.6 0.799 1490 1 0 2.22 4.89 8.15 PRS_PLINK_5e.04 614 Inflammatory diseases of female pelvic organs Female 7 23 11 genitourinary black 23, 7 6, 1 6, 0 5, 2 6, 4 0.693 0.692 0.317 0.499 2 0.599 9.6 0.301 2.47 0.903 0.044 1.35 0.00962 537 0.578 1.85 0.754 0.123 1.78 0.0845 363 0.625 1.9 0.742 0.13 1.87 0.048 64.8 PRS_PLINK_5e.04 614.1 Pelvic peritoneal adhesions, female (postoperative) (postinfection) Female 1 4 11 genitourinary black 4, 1 1, 0 1, 0 1, 1 1, 0 -0.0588 914000 1 0 0.943 0.649 2.49 0.36 5920 1 0 1.43 0.139 2 PRS_PLINK_5e.04 614.3 Pelvic inflammatory disease (PID) Female 2 4 11 genitourinary black 4, 2 1, 0 1, 1 1, 0 1, 1 3.41 28400000 1 0 30.4 4.15e-20 8.21e+25 0.469 11900 1 0 1.6 0.13 1.81 0.828 18800 1 0 2.29 0.173 4.52 PRS_PLINK_5e.04 614.31 Acute inflammatory pelvic disease Female 0 1 11 genitourinary black 1, 0 PRS_PLINK_5e.04 614.32 Chronic inflammatory pelvic disease Female 1 2 11 genitourinary black 2, 1 1, 1 1, 0 1, 1 1, 0 0.139 2470 1 0 1.15 0.136 4.48 -0.176 1430 1 0 0.838 0.617 1.91 PRS_PLINK_5e.04 614.33 Pelvic inflammatory disease, NOS Female 1 4 11 genitourinary black 4, 1 1, 0 1, 0 1, 0 1, 1 0.0814 5170 1 0 1.08 0.554 1.18 -3.59 9.85e+09 1 0 0.0275 5.18e-46 8.94e+64 PRS_PLINK_5e.04 614.4 Inflammatory diseases of uterus, except cervix Female 0 3 11 genitourinary black 3, 0 1 1 1 1 PRS_PLINK_5e.04 614.5 Inflammatory disease of cervix, vagina, and vulva Female 5 23 11 genitourinary black 23, 5 6, 1 6, 0 5, 1 6, 3 0.682 0.768 0.374 0.427 1.98 0.497 10.8 0.301 2.47 0.903 0.044 1.35 0.00962 537 0.546 1.83 0.766 0.116 1.73 0.0431 185 0.495 1.92 0.797 0.099 1.64 0.0526 48.4 PRS_PLINK_5e.04 614.51 Cervicitis and endocervicitis Female 0 4 11 genitourinary black 4, 0 1 1 1 1 PRS_PLINK_5e.04 614.52 Vaginitis and vulvovaginitis Female 2 23 11 genitourinary black 23, 2 6, 0 6, 0 5, 0 6, 2 0.982 0.923 0.287 0.542 2.67 0.313 32.9 1.09 2.17 0.615 0.211 2.98 0.0725 5230 PRS_PLINK_5e.04 614.53 Cyst or abscess of Bartholin's gland Female 2 2 11 genitourinary black 2, 2 1, 0 0, 1 1, 1 1, 0 -0.847 24300000 1 0 0.429 0.0199 11 -0.0133 164 1 0 0.987 0.823 1.18 -0.398 2660 1 0 0.671 0.101 1.46 PRS_PLINK_5e.04 614.54 Abscess or ulceration of vulva Female 1 1 11 genitourinary black 1, 1 -0.00117 494 1 0 0.999 0.989 1.08 PRS_PLINK_5e.04 615 Endometriosis Female 2 18 11 genitourinary black 18, 2 5, 0 4, 2 4, 0 5, 0 -1.09 1.07 0.31 0.508 0.337 0.002 2.59 -0.122 3.06 0.968 0.014 0.886 0.00251 420 PRS_PLINK_5e.04 618 Genital prolapse Female 3 19 11 genitourinary black 19, 3 5, 1 5, 0 4, 0 5, 2 0.354 0.73 0.628 0.202 1.42 0.377 6.1 -2.05 4.32 0.635 0.197 0.128 0.112 1.95 0.401 4.02 0.921 0.036 1.49 1.39 1.56 0.034 2.58 0.989 0.005 1.03 0.00588 42.1 PRS_PLINK_5e.04 618.1 Prolapse of vaginal walls Female 1 11 11 genitourinary black 11, 1 3, 0 3, 0 2, 1 3, 0 1.4 3.31 0.671 0.173 4.07 0.000361 3530 0.0632 5070000 1 0 1.07 0.157 4.06 PRS_PLINK_5e.04 618.2 Uterine/Uterovaginal prolapse Female 0 6 11 genitourinary black 6, 0 2 1 1 2 PRS_PLINK_5e.04 618.5 Prolapse of vaginal vault after hysterectomy Female 0 3 11 genitourinary black 3, 0 1 1 1 1 PRS_PLINK_5e.04 618.6 Vaginal enterocele, congenital or acquired Female 2 7 11 genitourinary black 7, 2 2, 1 2, 0 1, 0 2, 1 1.89 6.46 0.77 0.114 6.61 6.01 7.36 0.00445 128 1 0 1 0.761 1.22 -0.0469 148 1 0 0.954 0.907 1.15 -0.00157 21.5 1 0 0.998 0.661 1.23 PRS_PLINK_5e.04 619 Noninflammatory female genital disorders Female 12 19 11 genitourinary black 19, 12 5, 2 5, 6 4, 2 5, 2 -0.339 0.546 0.535 0.272 0.712 0.259 1.82 0.878 1.39 0.528 0.278 2.41 0.261 154 1.9 2.92 0.517 0.287 6.65 0.0738 112 -0.764 2.61 0.77 0.113 0.466 7.21e-05 22.6 PRS_PLINK_5e.04 619.1 Noninflammatory disorders of ovary, fallopian tube, and broad ligament Female 2 12 11 genitourinary black 12, 2 3, 0 3, 2 3, 0 3, 0 0.353 1.67 0.833 0.08 1.42 0.0231 46.1 -0.469 69.8 0.995 0.002 0.625 0.574 0.681 PRS_PLINK_5e.04 619.2 Disorders of uterus, NEC Female 1 6 11 genitourinary black 6, 1 2, 1 1, 0 1, 0 2, 0 0.037 373 1 0 1.04 0.83 1.64 -0.177 1960 1 0 0.837 0.743 1.57 0.249 1750 1 0 1.28 0.696 1.51 0.0754 1750 1 0 1.08 0.803 2.01 PRS_PLINK_5e.04 619.3 Noninflammatory disorders of cervix Female 0 5 11 genitourinary black 5, 0 2 1 1 1 PRS_PLINK_5e.04 619.4 Noninflammatory disorders of vagina Female 9 18 11 genitourinary black 18, 9 5, 1 4, 6 4, 1 5, 1 0.127 0.623 0.839 0.076 1.14 0.383 3.53 1.78 1.98 0.369 0.433 5.95 0.288 303 1.9 2.92 0.517 0.287 6.65 0.0738 112 0.336 3.02 0.912 0.04 1.4 0.00451 1.83 PRS_PLINK_5e.04 619.5 Noninflammatory disorders of vulva and perineum Female 2 12 11 genitourinary black 12, 2 3, 1 3, 0 3, 0 3, 1 -0.0537 1.14 0.962 0.017 0.948 0.177 13.2 1.01 481 0.998 0.001 2.75 0.000111 14400 2.35 58.3 0.968 0.014 10.5 8.99 12.9 0.287 2390 1 0 1.33 0.184 1.65 PRS_PLINK_5e.04 620 Dysplasia of female genital organs Female 0 6 11 genitourinary black 6, 0 2 1 1 2 PRS_PLINK_5e.04 620.1 Dysplasia of cervix Female 0 3 11 genitourinary black 3, 0 1 1 1 1 PRS_PLINK_5e.04 621 Endometrial hyperplasia Female 0 6 11 genitourinary black 6, 0 2 1 1 2 PRS_PLINK_5e.04 622 Polyp of female genital organs Female 3 20 11 genitourinary black 20, 3 5, 3 5, 0 5, 0 5, 0 -0.628 0.795 0.429 0.368 0.533 0.000938 2.45 -2.12 2.2 0.335 0.475 0.12 3.95e-06 2.72 -1.71 2.66 0.521 0.283 0.181 0.159 7.94 1.31 7.87 0.868 0.062 3.71 2.2e-05 138000 PRS_PLINK_5e.04 622.1 Polyp of corpus uteri Female 2 14 11 genitourinary black 14, 2 4, 2 3, 0 3, 0 4, 0 -0.685 1.2 0.569 0.245 0.504 0.00462 2.9 -13.6 92.6 0.884 0.054 1.3e-06 2.49e-07 9.94e-07 0.374 27.5 0.989 0.005 1.45 1.34 1.57 2.97 10.1 0.769 0.114 19.5 12.4 26.3 PRS_PLINK_5e.04 622.2 Mucous polyp of cervix Female 1 7 11 genitourinary black 7, 1 2, 1 2, 0 1, 0 2, 0 -0.67 167 0.997 0.001 0.512 0.245 1.98 -10.2 4.88e+08 1 0 3.81e-05 3.36e-11 8200 -2.35 1930 0.999 0 0.0952 5.65e-06 105000 -5.03 2310 0.998 0.001 0.00654 6e-09 1590 PRS_PLINK_5e.04 623 Hypertrophy of female genital organs Female 0 13 11 genitourinary black 13, 0 4 3 3 3 PRS_PLINK_5e.04 624 Symptoms involving female genital tract Female 4 17 11 genitourinary black 17, 4 5, 0 4, 2 4, 1 4, 1 0.383 1.19 0.748 0.126 1.47 0.174 48.3 1.64 3.11 0.598 0.223 5.16 0.0683 6.03 -0.0406 3.8 0.991 0.004 0.96 0.000218 54300 0.733 3.32 0.825 0.084 2.08 0.00733 258 PRS_PLINK_5e.04 624.1 Dystrophy of female genital tract Female 1 1 11 genitourinary black 1, 1 -0.012 114 1 0 0.988 0.964 1.06 PRS_PLINK_5e.04 624.2 Atrophy of female genital tract Female 0 1 11 genitourinary black 1, 0 PRS_PLINK_5e.04 624.9 stress incontinence, female Female 5 16 11 genitourinary black 16, 5 4, 0 4, 3 4, 1 4, 1 -0.846 0.912 0.354 0.452 0.429 0.00873 1.9 -1.75 7.6 0.818 0.087 0.173 0.152 0.2 0.446 27200 1 0 1.56 0.0764 96.2 0.112 323000 1 0 1.12 0.949 1.54 PRS_PLINK_5e.04 625 Pain and other symptoms associated with female genital organs Female 11 20 11 genitourinary black 20, 11 5, 0 5, 5 5, 3 5, 3 -0.3 0.628 0.633 0.199 0.741 0.157 2.31 2.21 1.89 0.243 0.614 9.13 0.635 456 0.667 2.41 0.782 0.107 1.95 0.0658 663 0.571 3.29 0.862 0.064 1.77 1.23e-05 6.89e+08 PRS_PLINK_5e.04 625.1 Dyspareunia Female 4 14 11 genitourinary black 14, 4 4, 0 3, 3 3, 1 4, 0 -0.822 1.11 0.46 0.337 0.44 9.99e-09 2.78 1.63 4.02 0.685 0.164 5.1 0.00884 11800000 0.364 1240 1 0 1.44 3.34 1.66 PRS_PLINK_5e.04 626 Disorders of menstruation and other abnormal bleeding from female genital tract Female 15 15 11 genitourinary black 15, 15 4, 2 4, 7 3, 6 4, 0 0.0813 0.577 0.888 0.052 1.08 0.384 3.68 -0.0366 1.87 0.984 0.007 0.964 0.719 37.9 0.967 1.98 0.625 0.204 2.63 0.0686 639 -6.26 14 0.655 0.184 0.0019 1e-14 215000 PRS_PLINK_5e.04 626.1 Irregular menstrual cycle/bleeding Female 13 15 11 genitourinary black 15, 13 4, 2 4, 6 3, 5 4, 0 0.0542 0.593 0.927 0.033 1.06 0.359 3.49 -0.0452 1.87 0.981 0.008 0.956 0.713 37.7 1.03 2.05 0.614 0.212 2.81 0.105 518 -6.26 14 0.655 0.184 0.0019 1e-14 215000 PRS_PLINK_5e.04 626.11 Absent or infrequent menstruation Female 7 10 11 genitourinary black 10, 7 3, 0 2, 4 2, 2 3, 1 -1.76 1.63 0.28 0.552 0.172 0.00351 2.05 1.86 111 0.987 0.006 6.4 2.66 182 0.598 5640 1 0 1.82 0.00435 5830 -0.0407 1480 1 0 0.96 0.249 7.58 PRS_PLINK_5e.04 626.12 Excessive or frequent menstruation Female 9 13 11 genitourinary black 13, 9 4, 1 3, 4 3, 4 3, 0 -0.409 0.865 0.637 0.196 0.664 0.141 3.32 0.479 3.15 0.879 0.056 1.61 0.0108 342 -1.45 3.46 0.676 0.17 0.235 0.000419 61.7 -4.51 825 0.996 0.002 0.0111 0.000262 0.00212 PRS_PLINK_5e.04 626.13 Irregular menstrual cycle Female 6 13 11 genitourinary black 13, 6 4, 1 3, 4 3, 1 3, 0 -0.245 1.01 0.808 0.092 0.783 0.124 5.17 -0.461 3.6 0.898 0.047 0.631 0.00128 175 1.9 30300000 1 0 6.68 0.0402 1690 -4.51 825 0.996 0.002 0.0111 0.000262 0.00212 PRS_PLINK_5e.04 626.14 Irregular menstrual bleeding Female 3 11 11 genitourinary black 11, 3 3, 3 3, 0 2, 0 3, 0 -2.11 2.44 0.387 0.412 0.122 5.36e-05 6.64 0.772 31.7 0.981 0.009 2.16 1.36 3.42 -1.98 16.6 0.905 0.043 0.139 0.0014 0.00955 -0.356 3260 1 0 0.701 6.15e-10 38600000 PRS_PLINK_5e.04 626.15 Infertility, female, associated with anovulation Female 2 6 11 genitourinary black 6, 2 2, 1 1, 1 1, 0 2, 0 0.129 176 0.999 0 1.14 1.42 3.13 0.32 3740 1 0 1.38 0.26 10.5 0.0661 2670 1 0 1.07 0.0318 213 -0.31 3670 1 0 0.733 0.116 2.48 PRS_PLINK_5e.04 626.2 Dysmenorrhea Female 5 12 11 genitourinary black 12, 5 3, 0 3, 2 3, 2 3, 1 0.12 0.851 0.888 0.052 1.13 0.194 5.58 4.77 296 0.987 0.006 118 101 181 0.249 469 1 0 1.28 0.245 2.05 -0.244 8110000 1 0 0.783 0.123 5.41 PRS_PLINK_5e.04 626.4 Premenstrual tension syndromes Female 1 2 11 genitourinary black 2, 1 1, 1 1, 0 1, 1 1, 0 0.101 2590 1 0 1.11 0.539 2.55 0.115 1740 1 0 1.12 0.627 2.15 PRS_PLINK_5e.04 626.8 Infertility, female Female 3 8 11 genitourinary black 8, 3 2, 2 2, 1 2, 0 2, 0 -1.16 1.97 0.558 0.254 0.315 0.0123 6.39 -0.0297 766 1 0 0.971 0.0165 23.1 -0.0785 3240000 1 0 0.925 0.0762 9.66 -5.41 3950 0.999 0 0.00448 2.17e-05 0.181 PRS_PLINK_5e.04 627 Menopausal and postmenopausal disorders Female 7 14 11 genitourinary black 14, 7 4, 0 3, 3 3, 3 4, 1 -0.0423 0.678 0.95 0.022 0.959 0.282 3.24 0.0268 3.5 0.994 0.003 1.03 0.00363 239 0.711 2.56 0.781 0.107 2.04 0.0623 165 -4.11 794 0.996 0.002 0.0164 0.00258 0.011 PRS_PLINK_5e.04 627.1 Postmenopausal bleeding Female 3 8 11 genitourinary black 8, 3 2, 1 2, 1 2, 0 2, 1 0.448 3.33 0.893 0.049 1.57 0.0106 420 -0.142 1920 1 0 0.867 0.217 1.71 -0.124 985 1 0 0.884 0.87 1.36 -0.0417 1490 1 0 0.959 0.944 1.35 PRS_PLINK_5e.04 627.2 Symptomatic menopause Female 2 14 11 genitourinary black 14, 2 4, 0 3, 1 3, 1 4, 0 0.805 1.22 0.508 0.294 2.24 0.259 453 0.346 83.8 0.997 0.001 1.41 0.00189 1060 0.53 948 1 0 1.7 7.89 16.8 PRS_PLINK_5e.04 627.21 Symptomatic artificial menopause Female 0 3 11 genitourinary black 3, 0 1 1 1 1 PRS_PLINK_5e.04 627.22 Need for Hormone replacement therapy (postmenopausal) Female 0 2 11 genitourinary black 2, 0 1 1 1 1 PRS_PLINK_5e.04 627.3 Postmenopausal atrophic vaginitis Female 2 8 11 genitourinary black 8, 2 2, 0 2, 1 2, 0 2, 1 -1.31 35.6 0.971 0.013 0.271 0.249 0.294 0.0244 1450 1 0 1.02 0.68 1.59 -8.86e-06 3120 1 0 1 0.558 3.17 PRS_PLINK_5e.04 627.4 Premenopausal menorrhagia Female 4 3 11 genitourinary black 3, 4 1, 0 1, 3 1, 1 1, 0 -0.0191 67.8 1 0 0.981 0.665 1.05 0.102 2150 1 0 1.11 0.194 6.82 0.139 5850 1 0 1.15 0.254 6.04 PRS_PLINK_5e.04 627.5 Premature menopause and other ovarian failure Female 1 3 11 genitourinary black 3, 1 1, 0 1, 1 1, 0 1, 0 0.0821 1680 1 0 1.09 0.609 2.01 0.133 2840 1 0 1.14 0.495 6.25 PRS_PLINK_5e.04 628 Ovarian cyst Female 3 14 11 genitourinary black 14, 3 4, 1 3, 1 3, 1 4, 0 -1.95 1.44 0.175 0.756 0.143 0.00404 1.25 2.49 22.2 0.911 0.041 12 9.48 14.7 -0.637 58.7 0.991 0.004 0.529 0.013 38.7 0.164 638 1 0 1.18 0.00187 2e+10 PRS_PLINK_5e.04 634 Miscarriage; stillbirth Female 4 12 12 pregnancy complications royalblue4 12, 4 3, 2 3, 1 3, 0 3, 1 0.188 1 0.851 0.07 1.21 0.25 19.6 -0.215 3.57 0.952 0.021 0.807 0.668 0.842 -0.0966 118 0.999 0 0.908 0.529 1.11 1.23 12800000 1 0 3.42 0.0233 4080 PRS_PLINK_5e.04 634.1 Missed abortion/Hydatidiform mole Female 0 5 12 pregnancy complications royalblue4 5, 0 2 1 1 1 PRS_PLINK_5e.04 635 Hemorrhage during pregnancy; childbirth and postpartum Female 2 8 12 pregnancy complications royalblue4 8, 2 2, 0 2, 2 2, 0 2, 0 -2.08 51.2 0.968 0.014 0.124 0.104 0.15 0.428 1640 1 0 1.53 0.534 1.8 PRS_PLINK_5e.04 635.2 Antepartum hemorrhage, abruptio placentae, and placenta previa Female 1 6 12 pregnancy complications royalblue4 6, 1 2, 0 1, 1 1, 0 2, 0 0.339 457 0.999 0 1.4 0.0842 26.4 0.0175 5340 1 0 1.02 0.527 1.4 PRS_PLINK_5e.04 635.3 Placenta previa and abruptio placenta Female 2 3 12 pregnancy complications royalblue4 3, 2 1, 0 1, 0 0, 2 1, 0 5.67 5560 0.999 0 289 0.000168 2.64e+08 1.62 1.69e+08 1 0 5.04 1.23e-07 2.8e+07 PRS_PLINK_5e.04 636 Early or threatened labor; hemorrhage in early pregnancy Female 4 11 12 pregnancy complications royalblue4 11, 4 3, 0 3, 2 2, 0 3, 2 0.665 1.21 0.583 0.234 1.95 0.312 21.1 0.0987 31.8 0.998 0.001 1.1 0.823 2.26 0.155 3820 1 0 1.17 7.24e-07 204 PRS_PLINK_5e.04 636.1 Threatened premature labor Female 0 7 12 pregnancy complications royalblue4 7, 0 2 2 1 2 PRS_PLINK_5e.04 636.2 Early onset of delivery Female 1 8 12 pregnancy complications royalblue4 8, 1 2, 1 2, 0 2, 0 2, 0 0.508 147 0.997 0.001 1.66 6.01e-05 46700 -0.0491 268 1 0 0.952 0.703 1.25 0.0927 4530 1 0 1.1 0.00142 6.17 0.315 5090 1 0 1.37 0.219 8.18 PRS_PLINK_5e.04 636.3 Hemorrhage in early pregnancy Female 3 5 12 pregnancy complications royalblue4 5, 3 2, 1 1, 0 1, 0 1, 2 0.37 36500 1 0 1.45 0.963 1.75 0.149 4620 1 0 1.16 0.599 1.2 0.0512 20100 1 0 1.05 0.00104 915 2.62 7030000 1 0 13.7 0.000447 1490000 PRS_PLINK_5e.04 636.8 Cervical incompetence Female 0 2 12 pregnancy complications royalblue4 2, 0 1 1 1 1 PRS_PLINK_5e.04 637 Short gestation; low birth weight; and fetal growth retardation Both 0 1 12 pregnancy complications royalblue4 1, 0 PRS_PLINK_5e.04 642 Hypertension complicating pregnancy, childbirth, and the puerperium Female 2 11 12 pregnancy complications royalblue4 11, 2 3, 0 3, 1 2, 0 3, 1 1.9 5.94 0.749 0.126 6.72 9e-05 453000 -1.63 205 0.994 0.003 0.196 0.00292 31.1 -0.777 701 0.999 0 0.46 0.00537 77.1 PRS_PLINK_5e.04 642.1 Preeclampsia and eclampsia Female 2 5 12 pregnancy complications royalblue4 5, 2 2, 0 1, 0 1, 0 1, 2 0.164 1130 1 0 1.18 0.654 5.47 0.0314 1280 1 0 1.03 0.711 1.57 PRS_PLINK_5e.04 643 Excessive vomiting in pregnancy Female 1 7 12 pregnancy complications royalblue4 7, 1 2, 0 2, 1 1, 0 2, 0 0.224 969 1 0 1.25 0.94 4.68 0.271 3530 1 0 1.31 0.447 1.7 PRS_PLINK_5e.04 643.1 Hyperemesis gravidarum Female 0 3 12 pregnancy complications royalblue4 3, 0 1 1 1 1 PRS_PLINK_5e.04 644 Anemia during pregnancy Female 1 3 12 pregnancy complications royalblue4 3, 1 1, 0 1, 0 1, 1 1, 0 -0.723 9860 1 0 0.485 3.28e-05 8910 -0.11 45500 1 0 0.896 0.123 5.17 PRS_PLINK_5e.04 646 Other complications of pregnancy NEC Female 2 11 12 pregnancy complications royalblue4 11, 2 3, 0 3, 0 2, 2 3, 0 1.11 2.48 0.654 0.184 3.03 0.172 40 1.27 312 0.997 0.001 3.55 0.325 340 PRS_PLINK_5e.04 647 Infectious and parasitic complications affecting pregnancy Female 0 3 12 pregnancy complications royalblue4 3, 0 1 1 1 1 PRS_PLINK_5e.04 647.1 Infections of genitourinary tract during pregnancy Female 1 5 12 pregnancy complications royalblue4 5, 1 2, 0 1, 0 1, 1 1, 0 -0.024 500 1 0 0.976 0.32 2.75 0.172 8960 1 0 1.19 0.522 1.86 PRS_PLINK_5e.04 647.3 Major puerperal infection Female 0 1 12 pregnancy complications royalblue4 1, 0 PRS_PLINK_5e.04 649 Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium Female 3 12 12 pregnancy complications royalblue4 12, 3 3, 0 3, 2 3, 0 3, 1 0.493 1.38 0.721 0.142 1.64 0.0907 23.5 0.47 74.4 0.995 0.002 1.6 0.000618 4130 0.925 581 0.999 0.001 2.52 0.0525 65.1 PRS_PLINK_5e.04 649.1 Diabetes or abnormal glucose tolerance complicating pregnancy Female 3 13 12 pregnancy complications royalblue4 13, 3 4, 0 3, 2 3, 0 3, 1 0.761 1.12 0.497 0.303 2.14 0.137 42.5 1.96 95.3 0.984 0.007 7.11 0.00154 51900 0.796 1300 1 0 2.22 0.0389 22.5 PRS_PLINK_5e.04 653 Problems associated with amniotic cavity and membranes Female 1 9 12 pregnancy complications royalblue4 9, 1 3, 0 2, 0 2, 1 2, 0 -1.03 13.9 0.941 0.026 0.357 0.334 0.384 1.66 2550 0.999 0 5.25 0.0182 4430 PRS_PLINK_5e.04 654.1 Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium Female 0 4 12 pregnancy complications royalblue4 4, 0 1 1 1 1 PRS_PLINK_5e.04 654.2 Rhesus isoimmunization in pregnancy Female 0 3 12 pregnancy complications royalblue4 3, 0 1 1 1 1 PRS_PLINK_5e.04 655 Known or suspected fetal abnormality affecting management of mother Female 3 15 12 pregnancy complications royalblue4 15, 3 4, 0 4, 2 3, 0 4, 1 0.238 0.885 0.788 0.104 1.27 0.272 6.39 1 2.38 0.674 0.171 2.72 0.0732 353 1.35 13.4 0.92 0.036 3.84 0.424 63.5 PRS_PLINK_5e.04 655.1 Abnormality in fetal heart rate or rhythm Female 2 12 12 pregnancy complications royalblue4 12, 2 3, 0 3, 2 3, 0 3, 0 0.752 2.21 0.733 0.135 2.12 0.0709 13 0.47 74.4 0.995 0.002 1.6 0.000618 4130 PRS_PLINK_5e.04 656 Other perinatal conditions of fetus or newborn Both 2 13 12 pregnancy complications royalblue4 13, 2 4, 0 3, 0 3, 2 3, 0 0.873 2.78 0.754 0.123 2.39 0.0496 321000 4.51 43.8 0.918 0.037 90.6 81.7 101 PRS_PLINK_5e.04 656.2 Respiratory conditions of fetus and newborn Both 0 3 12 pregnancy complications royalblue4 3, 0 1 1 1 1 PRS_PLINK_5e.04 669 Complications of labor and delivery NEC Female 1 15 12 pregnancy complications royalblue4 15, 1 4, 0 4, 0 3, 1 4, 0 -0.119 1.26 0.925 0.034 0.888 0.00121 221 1.09 10700000 1 0 2.99 0.00078 4740 PRS_PLINK_5e.04 671 Venous/cerebrovascular complications embolism in pregnancy and the puerperium Female 0 6 12 pregnancy complications royalblue4 6, 0 2 1 1 2 PRS_PLINK_5e.04 674 Other complications of the puerperium NEC Female 0 4 12 pregnancy complications royalblue4 4, 0 1 1 1 1 PRS_PLINK_5e.04 676 Other disorders of the breast associated with childbirth and disorders of lactation Female 0 5 12 pregnancy complications royalblue4 5, 0 2 1 1 1 PRS_PLINK_5e.04 681 Superficial cellulitis and abscess Both 13 50 13 dermatologic firebrick 50, 13 12, 2 12, 4 12, 2 13, 5 0.314 0.346 0.364 0.438 1.37 0.716 2.66 -0.132 1.17 0.91 0.041 0.876 0.0385 8.88 -0.0501 1.04 0.962 0.017 0.951 0.0116 7.28 0.771 1.03 0.456 0.341 2.16 0.375 19.5 PRS_PLINK_5e.04 681.1 Cellulitis and abscess of fingers/toes Both 4 24 13 dermatologic firebrick 24, 4 5, 0 6, 0 6, 0 6, 4 0.972 0.654 0.137 0.863 2.64 0.879 9900 1.37 1.56 0.379 0.421 3.94 0.377 68.4 PRS_PLINK_5e.04 681.2 Cellulitis and abscess of face/neck Both 2 21 13 dermatologic firebrick 21, 2 6, 0 5, 1 5, 0 5, 1 0.141 0.905 0.876 0.058 1.15 0.0773 14 -0.066 2.71 0.981 0.009 0.936 0.00111 528 0.139 17.5 0.994 0.003 1.15 2.9e-06 510000 PRS_PLINK_5e.04 681.3 Cellulitis and abscess of arm/hand Both 5 30 13 dermatologic firebrick 30, 5 7, 1 7, 1 7, 1 8, 2 0.255 0.439 0.56 0.252 1.29 0.572 3.07 -0.427 1.52 0.779 0.109 0.653 0.00485 14.5 -0.345 2.11 0.87 0.06 0.708 0.00138 25.1 0.17 1.33 0.898 0.047 1.19 0.00455 18.9 PRS_PLINK_5e.04 681.5 Cellulitis and abscess of leg, except foot Both 5 31 13 dermatologic firebrick 31, 5 7, 1 8, 1 7, 1 8, 2 -0.0836 0.496 0.866 0.062 0.92 0.293 3.34 -1.29 1.73 0.457 0.34 0.276 2.01e-06 6.01 0.398 2.04 0.845 0.073 1.49 0.00334 127 -0.346 1.74 0.842 0.075 0.708 0.000128 10.7 PRS_PLINK_5e.04 681.6 Cellulitis and abscess of foot, toe Both 5 26 13 dermatologic firebrick 26, 5 6, 1 6, 1 6, 1 7, 2 0.0528 0.592 0.929 0.032 1.05 0.314 3.23 -1.3 1.85 0.482 0.317 0.272 0.00479 5.71 0.706 1.85 0.702 0.154 2.03 0.00879 77.1 -1.06 2.04 0.603 0.219 0.346 2.81e-06 10.2 PRS_PLINK_5e.04 681.7 Cellulitis and abscess of trunk Both 2 27 13 dermatologic firebrick 27, 2 7, 0 7, 1 6, 1 7, 0 -0.0999 0.704 0.887 0.052 0.905 0.0395 18.9 -0.00638 2.53 0.998 0.001 0.994 0.000755 228 0.863 1.91 0.652 0.186 2.37 0.0223 170 PRS_PLINK_5e.04 686 Other local infections of skin and subcutaneous tissue Both 2 26 13 dermatologic firebrick 26, 2 7, 1 6, 0 6, 1 7, 0 -0.56 0.725 0.44 0.356 0.571 5.48e-05 2.19 -1.68 1.89 0.373 0.429 0.186 0.00176 3.58 1.13 1.8 0.528 0.277 3.11 0.136 8470 -0.593 1.78 0.738 0.132 0.552 5.2e-05 8.13 PRS_PLINK_5e.04 686.1 Carbuncle and furuncle Both 1 14 13 dermatologic firebrick 14, 1 3, 1 3, 0 3, 0 4, 0 -0.0987 1.63 0.952 0.021 0.906 0.0277 48.1 0.00107 139 1 0 1 0.856 1.45 -0.193 4870 1 0 0.824 0.781 2.99 -1.52 664 0.998 0.001 0.219 0.0237 0.0907 PRS_PLINK_5e.04 686.2 Impetigo Both 0 5 13 dermatologic firebrick 5, 0 2 1 1 1 PRS_PLINK_5e.04 686.3 Pilonidal cyst Both 1 6 13 dermatologic firebrick 6, 1 2, 0 1, 0 1, 1 2, 0 5.93 14100000 1 0 376 18.3 1.05e+10 -0.458 4290 1 0 0.632 0.616 1.62 PRS_PLINK_5e.04 686.4 Pyogenic granuloma Both 0 3 13 dermatologic firebrick 3, 0 1 1 1 1 PRS_PLINK_5e.04 686.5 Pyoderma Both 1 2 13 dermatologic firebrick 2, 1 1, 1 1, 0 1, 1 1, 0 -0.00899 73.2 1 0 0.991 0.848 1.06 0.00301 51.9 1 0 1 0.937 1.12 PRS_PLINK_5e.04 687 Symptoms affecting skin Both 4 18 13 dermatologic firebrick 18, 4 5, 1 4, 1 4, 1 5, 1 0.238 0.795 0.765 0.116 1.27 0.274 28.9 -0.683 16.7 0.967 0.014 0.505 0.00633 1.19 0.908 2.52 0.718 0.144 2.48 2.21 2.69 -0.68 5.99 0.91 0.041 0.507 5.95e-05 4710 PRS_PLINK_5e.04 687.1 Rash and other nonspecific skin eruption Both 22 36 13 dermatologic firebrick 36, 22 8, 8 9, 9 9, 2 9, 3 -0.393 0.332 0.236 0.628 0.675 0.35 1.21 -0.857 0.951 0.368 0.434 0.425 0.0563 2.15 -1.04 1.2 0.388 0.411 0.353 0.0324 2.75 -1.38 1.2 0.251 0.601 0.252 0.0168 1.78 PRS_PLINK_5e.04 687.3 Changes in skin texture Both 2 8 13 dermatologic firebrick 8, 2 2, 0 2, 1 2, 0 2, 1 0.131 3040000 1 0 1.14 0.38 3.9 -1.69 28600 1 0 0.184 2.92e-06 2180 -2.28 5960 1 0 0.102 1.74e-06 293 PRS_PLINK_5e.04 687.4 Disturbance of skin sensation Both 9 36 13 dermatologic firebrick 36, 9 8, 5 9, 2 9, 1 9, 1 -0.722 0.544 0.185 0.733 0.486 0.142 1.36 -1.94 1.4 0.165 0.782 0.144 0.00386 1.35 -0.609 1.24 0.623 0.205 0.544 0.0499 4.15 -0.772 1.95 0.692 0.16 0.462 0.00177 38 PRS_PLINK_5e.04 689 Disorder of skin and subcutaneous tissue NOS Both 16 48 13 dermatologic firebrick 48, 16 11, 3 12, 6 12, 3 12, 4 -0.104 0.375 0.783 0.106 0.902 0.433 1.81 -0.345 1 0.731 0.136 0.708 0.102 4.31 -0.0726 0.974 0.941 0.027 0.93 0.155 5.47 -0.774 1.11 0.487 0.313 0.461 0.034 3.17 PRS_PLINK_5e.04 690 Erythematosquamous dermatosis Both 9 32 13 dermatologic firebrick 32, 9 8, 2 8, 3 8, 1 8, 3 0.241 0.497 0.628 0.202 1.27 0.434 3.44 -1.24 1.78 0.486 0.313 0.289 2.66e-06 5.28 -1.58 1.91 0.407 0.39 0.205 1.8e-05 4.35 0.143 1.58 0.928 0.032 1.15 0.0322 2660 PRS_PLINK_5e.04 690.1 Seborrheic dermatitis Both 9 32 13 dermatologic firebrick 32, 9 8, 2 8, 3 8, 1 8, 3 0.241 0.497 0.628 0.202 1.27 0.434 3.44 -1.24 1.78 0.486 0.313 0.289 2.66e-06 5.28 -1.58 1.91 0.407 0.39 0.205 1.8e-05 4.35 0.143 1.58 0.928 0.032 1.15 0.0322 2660 PRS_PLINK_5e.04 691 Congenital anomalies of skin Both 1 10 13 dermatologic firebrick 10, 1 3, 0 2, 1 2, 0 3, 0 -0.407 1.8 0.822 0.085 0.666 0.0417 11.2 -0.241 1770 1 0 0.785 0.473 1.74 PRS_PLINK_5e.04 691.3 Congenital pigmentary anomalies of skin Both 0 2 13 dermatologic firebrick 2, 0 1 1 1 1 PRS_PLINK_5e.04 694 Dyschromia and Vitiligo Both 4 22 13 dermatologic firebrick 22, 4 5, 0 5, 2 5, 1 6, 1 -0.326 0.741 0.66 0.18 0.722 0.0815 3.26 0.189 4.64 0.968 0.014 1.21 0.00105 30700 -0.393 5.72 0.945 0.024 0.675 0.0152 27.2 -0.139 3.64 0.969 0.013 0.87 0.00014 1290 PRS_PLINK_5e.04 694.1 Vitiligo Both 1 3 13 dermatologic firebrick 3, 1 1, 0 1, 1 1, 0 1, 1 -0.495 8300 1 0 0.61 0.00238 37 PRS_PLINK_5e.04 694.2 Other dyschromia Both 3 19 13 dermatologic firebrick 19, 3 5, 0 5, 2 4, 0 5, 1 -0.235 0.921 0.798 0.098 0.79 0.0031 4.44 0.136 4.39 0.975 0.011 1.15 0.000635 1090 0.196 6.71 0.977 0.01 1.22 1.47e-05 64600 PRS_PLINK_5e.04 694.3 Vascular disorders of skin Both 0 1 13 dermatologic firebrick 1, 0 PRS_PLINK_5e.04 695 Erythematous conditions Both 13 33 13 dermatologic firebrick 33, 13 9, 6 8, 3 8, 2 8, 2 -0.524 0.447 0.241 0.618 0.592 0.238 1.29 -2.88 1.97 0.144 0.842 0.0561 0.000199 1.81 -0.914 1.71 0.594 0.227 0.401 0.00674 7.67 -1.67 1.54 0.277 0.557 0.188 0.00158 2.43 PRS_PLINK_5e.04 695.2 Bullous dermatoses Both 0 1 13 dermatologic firebrick 1, 0 PRS_PLINK_5e.04 695.3 Rosacea Both 3 18 13 dermatologic firebrick 18, 3 5, 0 4, 0 4, 2 5, 1 0.479 0.8 0.55 0.26 1.61 0.445 21.9 0.85 2.6 0.744 0.128 2.34 0.0296 98.2 1.3 4.49 0.773 0.112 3.66 0.00733 4070 PRS_PLINK_5e.04 695.4 Lupus (localized and systemic) Both 3 10 13 dermatologic firebrick 10, 3 3, 1 2, 1 2, 0 3, 1 -0.399 1.57 0.8 0.097 0.671 0.000195 18.5 -0.621 714 0.999 0 0.537 0.488 3.61 -0.306 4e+07 1 0 0.736 0.0775 5.09 0.025 488 1 0 1.03 0.596 2.87 PRS_PLINK_5e.04 695.41 Cutaneous lupus erythematosus Both 1 3 13 dermatologic firebrick 3, 1 1, 0 1, 0 1, 1 1, 0 -0.191 3340 1 0 0.826 0.215 3.15 -0.0206 66.6 1 0 0.98 0.802 1.21 PRS_PLINK_5e.04 695.42 Systemic lupus erythematosus Both 3 9 13 dermatologic firebrick 9, 3 3, 1 2, 1 2, 0 2, 1 -1.37 2.59 0.596 0.224 0.253 0.00368 9.6 -0.047 125 1 0 0.954 0.31 2.12 0.113 1430 1 0 1.12 0.189 7.65 -0.129 405 1 0 0.879 0.247 1.96 PRS_PLINK_5e.04 695.7 Prurigo and Lichen Both 3 3 13 dermatologic firebrick 3, 3 1, 1 1, 2 1, 0 1, 1 -0.204 2190 1 0 0.815 0.655 1.19 -0.625 10200 1 0 0.535 0.477 2.79 -0.0187 140 1 0 0.982 0.932 1.11 PRS_PLINK_5e.04 695.8 Other specified erythematous conditions Both 4 7 13 dermatologic firebrick 7, 4 2, 4 2, 0 1, 0 2, 0 -2.01 2.03 0.322 0.492 0.133 0.00423 2.05 -0.762 5050000 1 0 0.467 0.0241 6.41 -0.723 2930 1 0 0.485 0.00257 1110 -0.312 4e+07 1 0 0.732 1.43e-06 26500 PRS_PLINK_5e.04 695.9 Unspecified erythematous condition Both 0 8 13 dermatologic firebrick 8, 0 2 2 2 2 PRS_PLINK_5e.04 696 Psoriasis and related disorders Both 4 9 13 dermatologic firebrick 9, 4 3, 2 2, 0 2, 1 2, 1 -0.181 0.955 0.85 0.071 0.835 0.0367 4.1 -0.466 333 0.999 0 0.627 0.0616 13.8 0.012 390 1 0 1.01 0.582 1.83 0.0319 764 1 0 1.03 0.343 2.99 PRS_PLINK_5e.04 696.3 Pityriasis Both 1 3 13 dermatologic firebrick 3, 1 1, 1 1, 0 1, 0 1, 1 1.02 1090 0.999 0 2.77 0.0912 216 0.00504 15.1 1 0 1.01 0.941 1.08 1.39 5590 1 0 4 0.0345 782 PRS_PLINK_5e.04 696.4 Psoriasis Both 3 10 13 dermatologic firebrick 10, 3 3, 1 2, 0 2, 0 3, 2 -0.554 1.02 0.585 0.233 0.575 0.0734 2.6 -0.00604 4420 1 0 0.994 1.26e-08 6.59e+09 -0.0734 1670 1 0 0.929 0.288 5.43 -0.429 127 0.997 0.001 0.651 0.706 1.13 PRS_PLINK_5e.04 696.41 Psoriasis vulgaris Both 3 8 13 dermatologic firebrick 8, 3 2, 1 2, 0 2, 1 2, 1 -0.567 1.04 0.584 0.233 0.567 0.0289 2.66 0.114 2380 1 0 1.12 0.459 3.3 -0.0303 166 1 0 0.97 0.407 1.85 0.083 1920 1 0 1.09 0.00351 1660 PRS_PLINK_5e.04 696.42 Psoriatic arthropathy Both 1 2 13 dermatologic firebrick 2, 1 1, 1 1, 0 1, 1 1, 0 -0.173 55.5 0.998 0.001 0.841 0.796 1.29 0.00483 59.2 1 0 1 0.92 1.13 PRS_PLINK_5e.04 697 Sarcoidosis Both 0 4 13 dermatologic firebrick 4, 0 1 1 1 1 PRS_PLINK_5e.04 698 Pruritus and related conditions Both 3 33 13 dermatologic firebrick 33, 3 9, 1 8, 1 8, 0 8, 1 -1.08 0.936 0.247 0.608 0.338 0.00392 2.13 -0.521 1.58 0.742 0.13 0.594 0.000489 17.1 0.658 1.8 0.715 0.146 1.93 0.0228 100 0.605 2.62 0.817 0.088 1.83 0.000747 7010 PRS_PLINK_5e.04 700 Corns and callosities Both 10 20 13 dermatologic firebrick 20, 10 5, 4 5, 3 5, 1 5, 2 -0.806 0.74 0.276 0.559 0.446 0.0313 1.47 0.0586 338 1 0 1.06 0.498 1.28 -2.28 3.72 0.54 0.267 0.103 0.000117 47.8 -0.0692 390 1 0 0.933 0.119 2.04 PRS_PLINK_5e.04 701 Other hypertrophic and atrophic conditions of skin Both 9 47 13 dermatologic firebrick 47, 9 11, 3 12, 3 11, 1 12, 2 -0.397 0.463 0.391 0.407 0.672 0.247 1.6 -1.36 1.33 0.307 0.512 0.258 0.000109 3.31 -0.581 1.47 0.692 0.16 0.559 0.0128 23.8 -0.759 1.35 0.573 0.242 0.468 0.00427 5.2 PRS_PLINK_5e.04 701.1 Keratoderma, acquired Both 2 8 13 dermatologic firebrick 8, 2 2, 2 2, 0 2, 0 2, 0 -0.952 5.6 0.865 0.063 0.386 0.371 0.401 4.52 7060 0.999 0 92.1 1e-25 1.44e+25 -0.36 13900000 1 0 0.697 9.49e-15 4.59e+10 -0.261 190 0.999 0 0.77 0.0786 10.1 PRS_PLINK_5e.04 701.2 Scar conditions and fibrosis of skin Both 1 24 13 dermatologic firebrick 24, 1 6, 0 6, 0 6, 1 6, 0 -0.0716 0.961 0.941 0.027 0.931 0.0581 18 -0.261 5.76 0.964 0.016 0.77 2.22e-06 68500 PRS_PLINK_5e.04 701.3 Circumscribed scleroderma Both 1 8 13 dermatologic firebrick 8, 1 2, 0 2, 0 2, 0 2, 1 0.205 3590 1 0 1.23 0.611 5.86 0.291 9670 1 0 1.34 0.0578 1.68 PRS_PLINK_5e.04 701.4 Keloid scar Both 0 5 13 dermatologic firebrick 5, 0 2 1 1 1 PRS_PLINK_5e.04 701.5 Abnormal granulation tissue Both 0 4 13 dermatologic firebrick 4, 0 1 1 1 1 PRS_PLINK_5e.04 702 Degenerative skin conditions and other dermatoses Both 11 31 13 dermatologic firebrick 31, 11 8, 2 8, 4 7, 1 8, 4 -0.321 0.684 0.639 0.195 0.725 0.108 2.71 0.0821 1.35 0.951 0.022 1.09 0.0786 59.1 -0.646 1.41 0.646 0.19 0.524 0.0101 10.7 -1.78 1.69 0.294 0.532 0.169 0.000503 3.74 PRS_PLINK_5e.04 702.1 Actinic keratosis Both 3 28 13 dermatologic firebrick 28, 3 7, 2 7, 0 7, 0 7, 1 0.124 0.719 0.863 0.064 1.13 0.132 10.8 0.809 2.04 0.691 0.16 2.25 0.0729 155 0.557 1.94 0.773 0.112 1.75 0.0653 222 0.202 2.79 0.942 0.026 1.22 0.000499 219 PRS_PLINK_5e.04 702.2 Seborrheic keratosis Both 9 32 13 dermatologic firebrick 32, 9 8, 2 8, 4 8, 1 8, 2 -0.165 0.546 0.762 0.118 0.848 0.226 3.65 -1.31 1.53 0.395 0.404 0.271 0.00283 3.24 -0.423 1.55 0.785 0.105 0.655 0.0256 18.9 -0.66 1.72 0.702 0.154 0.517 0.00264 13.4 PRS_PLINK_5e.04 702.4 Degenerative skin disorders Both 0 1 13 dermatologic firebrick 1, 0 PRS_PLINK_5e.04 703 Diseases of nail, NOS Both 8 20 13 dermatologic firebrick 20, 8 5, 1 5, 2 5, 2 5, 3 0.0676 0.552 0.902 0.045 1.07 0.39 5.34 0.151 1.76 0.932 0.031 1.16 0.0222 1.48 0.612 2.24 0.785 0.105 1.84 0.0593 1230 -0.409 1.92 0.831 0.08 0.664 0.00364 22.2 PRS_PLINK_5e.04 703.1 Ingrowing nail Both 5 18 13 dermatologic firebrick 18, 5 4, 1 4, 1 4, 1 5, 2 0.17 0.558 0.761 0.119 1.19 0.447 4.11 -0.291 2.22 0.896 0.048 0.748 0.587 0.875 0.0449 1.64 0.978 0.01 1.05 0.0489 19.1 -0.398 2.26 0.86 0.065 0.672 0.000412 23.7 PRS_PLINK_5e.04 704 Diseases of hair and hair follicles Both 9 40 13 dermatologic firebrick 40, 9 9, 3 10, 3 10, 2 10, 1 -0.102 0.421 0.808 0.093 0.903 0.378 1.92 -0.336 1.22 0.782 0.107 0.715 0.074 6.37 -0.308 1.46 0.833 0.08 0.735 0.0165 12.3 -0.308 1.38 0.823 0.085 0.735 0.0449 9.16 PRS_PLINK_5e.04 704.1 Alopecia Both 2 17 13 dermatologic firebrick 17, 2 5, 0 4, 1 4, 0 4, 1 0.704 0.828 0.395 0.403 2.02 0.502 245 0.61 2.78 0.826 0.083 1.84 0.0221 675 0.904 2.21 0.683 0.166 2.47 0.104 87.6 PRS_PLINK_5e.04 704.11 Alopecia Areata Both 1 2 13 dermatologic firebrick 2, 1 1, 0 0, 1 1, 0 1, 0 0.0123 110 1 0 1.01 0.893 1.18 -0.00101 13.4 1 0 0.999 0.982 1.01 PRS_PLINK_5e.04 704.2 Hirsutism Both 3 3 13 dermatologic firebrick 3, 3 1, 2 1, 1 1, 0 1, 2 -3.14 1820 0.999 0.001 0.0432 7.6e-16 1.05e+14 -18.5 18100 0.999 0 9.47e-09 2.76e-11 6.7e+08 -0.972 21300 1 0 0.378 0.162 20.9 PRS_PLINK_5e.04 704.8 Other specified diseases of hair and hair follicles Both 7 24 13 dermatologic firebrick 24, 7 5, 3 6, 1 6, 3 6, 0 -0.525 0.629 0.404 0.394 0.591 0.139 1.73 -0.442 1.77 0.803 0.095 0.643 0.0347 12.3 -0.607 2.06 0.768 0.114 0.545 0.423 14 -0.733 2.19 0.738 0.132 0.481 0.00195 15.7 PRS_PLINK_5e.04 705 Disorders of sweat glands Both 1 7 13 dermatologic firebrick 7, 1 2, 0 2, 0 1, 0 2, 1 0.15 41.4 0.997 0.001 1.16 0.756 2.6 -0.0137 1730 1 0 0.986 0.545 1.64 PRS_PLINK_5e.04 705.1 Dyshidrosis Both 0 1 13 dermatologic firebrick 1, 0 PRS_PLINK_5e.04 705.3 Hidradenitis Both 0 5 13 dermatologic firebrick 5, 0 2 1 1 1 PRS_PLINK_5e.04 705.8 Hyperhidrosis Both 3 15 13 dermatologic firebrick 15, 3 4, 0 4, 2 3, 1 4, 0 -0.206 1.47 0.888 0.051 0.814 0.000406 31.1 0.112 9.43 0.991 0.004 1.12 0.244 5.19 -0.0736 5.26 0.989 0.005 0.929 0.00373 395 PRS_PLINK_5e.04 706 Diseases of sebaceous glands Both 19 43 13 dermatologic firebrick 43, 19 10, 4 11, 8 10, 4 11, 3 -0.234 0.34 0.491 0.309 0.791 0.398 1.46 0.376 0.818 0.646 0.19 1.46 0.33 6.67 0.779 1.22 0.522 0.282 2.18 0.242 40.3 -2.01 1.56 0.198 0.703 0.134 0.101 1.76 PRS_PLINK_5e.04 706.1 Acne Both 6 32 13 dermatologic firebrick 32, 6 7, 1 8, 3 8, 2 8, 0 -0.436 0.468 0.352 0.454 0.647 0.209 1.46 -0.0454 1.39 0.974 0.011 0.956 0.0575 10.4 -0.25 2.21 0.91 0.041 0.779 0.00126 209 -0.814 1.83 0.656 0.183 0.443 0.00362 7.94 PRS_PLINK_5e.04 706.2 Sebaceous cyst Both 9 29 13 dermatologic firebrick 29, 9 7, 2 7, 5 7, 0 7, 2 -0.116 0.454 0.798 0.098 0.89 0.377 2.03 0.424 1.13 0.707 0.151 1.53 0.226 12.6 -1.88 2.32 0.416 0.381 0.152 0.0011 4.11 0.751 1.74 0.667 0.176 2.12 0.0129 113 PRS_PLINK_5e.04 706.3 Seborrhea Both 0 1 13 dermatologic firebrick 1, 0 PRS_PLINK_5e.04 706.8 Other specified diseases of sebaceous glands Both 9 18 13 dermatologic firebrick 18, 9 5, 1 4, 4 4, 1 5, 3 -0.447 0.768 0.561 0.251 0.64 0.108 2.41 1.79 2.07 0.387 0.412 6 0.304 1610 -0.932 18.6 0.96 0.018 0.394 1.3e-05 13200 1.32 1.97 0.503 0.298 3.75 0.059 5380 PRS_PLINK_5e.04 707 Chronic ulcer of skin Both 7 35 13 dermatologic firebrick 35, 7 9, 1 9, 1 8, 3 9, 2 0.0486 0.575 0.933 0.03 1.05 0.309 3.24 -1.68 1.78 0.345 0.462 0.187 7.64e-06 3.92 0.919 1.46 0.531 0.275 2.51 0.123 2010 0.154 1.58 0.922 0.035 1.17 0.00413 995 PRS_PLINK_5e.04 707.1 Decubitus ulcer Both 2 14 13 dermatologic firebrick 14, 2 4, 0 3, 0 3, 1 4, 1 -0.496 1.11 0.656 0.183 0.609 0.0211 7.88 0.213 15100000 1 0 1.24 0.0934 35 -0.408 39.7 0.992 0.004 0.665 0.321 1.14 PRS_PLINK_5e.04 707.2 Chronic ulcer of leg or foot Both 4 21 13 dermatologic firebrick 21, 4 6, 1 5, 0 5, 2 5, 1 -0.414 0.866 0.633 0.199 0.661 0.00393 12.6 -1.11 2.13 0.602 0.22 0.329 0.00348 9.25 1.02 2.11 0.628 0.202 2.78 0.0483 525 -2.08 3.92 0.595 0.225 0.125 1.1e-05 26 PRS_PLINK_5e.04 707.3 Chronic ulcer of unspecified site Both 2 21 13 dermatologic firebrick 21, 2 6, 0 5, 1 5, 0 5, 1 -0.21 0.769 0.784 0.105 0.81 0.0338 3.92 -0.56 2.61 0.83 0.081 0.571 0.0097 631 0.158 5.09 0.975 0.011 1.17 0.000133 10600 PRS_PLINK_5e.04 709 Diffuse diseases of connective tissue Both 5 18 13 dermatologic firebrick 18, 5 5, 3 4, 1 4, 0 5, 1 -0.245 1 0.807 0.093 0.783 0.107 33.9 0.682 3.38 0.84 0.076 1.98 5.02e-05 1140000 0.876 2.91 0.763 0.117 2.4 0.000884 623 -0.826 2.32 0.722 0.142 0.438 0.00257 65.5 PRS_PLINK_5e.04 709.2 Sicca syndrome Both 3 7 13 dermatologic firebrick 7, 3 2, 2 2, 0 1, 0 2, 1 -0.281 8.69 0.974 0.011 0.755 0.296 0.817 -1.83 519 0.997 0.001 0.161 0.000852 200 10.7 9150 0.999 0 43600 3.47e-14 2.08e+23 0.133 931 1 0 1.14 0.441 2.96 PRS_PLINK_5e.04 709.7 Unspecified diffuse connective tissue disease Both 3 14 13 dermatologic firebrick 14, 3 4, 1 3, 1 3, 0 4, 1 -0.281 0.93 0.763 0.118 0.755 0.041 5.16 5.46 33300000 1 0 235 0.155 9710000 0.561 887 0.999 0 1.75 1.31 1.25 -0.445 2.69 0.869 0.061 0.641 0.000571 703 PRS_PLINK_5e.04 710 Osteomyelitis, periostitis, and other infections involving bone Both 2 17 14 musculoskeletal darkolivegreen 17, 2 5, 0 4, 0 4, 1 4, 1 -0.0909 1 0.928 0.033 0.913 0.00741 14.6 0.954 2.19 0.664 0.178 2.6 0.107 94.5 0.379 4.59 0.934 0.03 1.46 1.32 1.56 PRS_PLINK_5e.04 710.1 Osteomyelitis Both 2 18 14 musculoskeletal darkolivegreen 18, 2 5, 0 4, 0 4, 1 5, 1 0.00938 0.974 0.992 0.003 1.01 0.0113 15.5 1.02 1.95 0.6 0.222 2.78 0.128 89.8 0.417 3.35 0.901 0.045 1.52 0.00156 407 PRS_PLINK_5e.04 710.11 Acute osteomyelitis Both 0 8 14 musculoskeletal darkolivegreen 8, 0 2 2 2 2 PRS_PLINK_5e.04 710.12 Chronic osteomyelitis Both 0 10 14 musculoskeletal darkolivegreen 10, 0 3 2 2 3 PRS_PLINK_5e.04 710.19 Unspecified osteomyelitis Both 2 18 14 musculoskeletal darkolivegreen 18, 2 5, 0 4, 0 4, 1 5, 1 0.0891 0.865 0.918 0.037 1.09 0.0216 23.1 1.07 2.19 0.625 0.204 2.92 0.142 103 0.717 3.85 0.852 0.069 2.05 0.0026 1320 PRS_PLINK_5e.04 711 Arthropathy associated with infections Both 0 6 14 musculoskeletal darkolivegreen 6, 0 2 1 1 2 PRS_PLINK_5e.04 711.1 Pyogenic arthritis Both 0 2 14 musculoskeletal darkolivegreen 2, 0 1 1 1 1 PRS_PLINK_5e.04 712 Infective connective tissue disorders Both 0 1 14 musculoskeletal darkolivegreen 1, 0 PRS_PLINK_5e.04 713 Arthropathy associated with other disorders classified elsewhere Both 3 9 14 musculoskeletal darkolivegreen 9, 3 3, 1 2, 0 2, 1 2, 1 -0.211 165 0.999 0 0.81 0.476 0.888 0.164 982 1 0 1.18 0.24 13.7 -0.00403 475 1 0 0.996 0.812 1.2 0.105 1540 1 0 1.11 0.513 2.93 PRS_PLINK_5e.04 713.5 Arthropathy associated with neurological disorders Both 3 6 14 musculoskeletal darkolivegreen 6, 3 2, 0 1, 1 1, 0 2, 2 0.0304 450 1 0 1.03 0.667 1.66 0.26 2320 1 0 1.3 0.572 9.29 -0.0679 4390 1 0 0.934 0.358 3.33 PRS_PLINK_5e.04 714 Rheumatoid arthritis and other inflammatory polyarthropathies Both 4 19 14 musculoskeletal darkolivegreen 19, 4 5, 2 5, 1 4, 0 5, 1 -0.296 0.733 0.686 0.163 0.744 0.164 3.36 -1.85 2.51 0.46 0.337 0.156 0.000187 6.09 -0.0907 2.11 0.966 0.015 0.913 0.00811 69.3 -0.624 3.04 0.837 0.077 0.536 6.6e-05 498 PRS_PLINK_5e.04 714.1 Rheumatoid arthritis Both 1 13 14 musculoskeletal darkolivegreen 13, 1 4, 0 3, 0 3, 0 3, 1 -0.0645 0.967 0.947 0.024 0.938 0.0955 11.2 -1.04 775 0.999 0 0.354 0.163 0.169 PRS_PLINK_5e.04 714.2 Juvenile rheumatoid arthritis Both 0 2 14 musculoskeletal darkolivegreen 2, 0 1 1 1 1 PRS_PLINK_5e.04 715 Other inflammatory spondylopathies Both 4 8 14 musculoskeletal darkolivegreen 8, 4 2, 2 2, 2 2, 0 2, 0 -0.889 1.39 0.523 0.281 0.411 0.0431 2.85 0.512 332 0.999 0.001 1.67 2.27 5.03 -0.0927 4000 1 0 0.912 0.31 2.3 -0.0232 109 1 0 0.977 0.577 1.2 PRS_PLINK_5e.04 715.1 Sacroiliitis NEC Both 2 1 14 musculoskeletal darkolivegreen 1, 2 -0.919 2820000 1 0 0.399 0.0462 6.85 PRS_PLINK_5e.04 715.2 Ankylosing spondylitis Both 1 3 14 musculoskeletal darkolivegreen 3, 1 1, 1 1, 0 1, 0 1, 1 -0.0238 456 1 0 0.977 0.658 1.19 -0.000187 137 1 0 1 0.931 1.08 -0.388 4080 1 0 0.678 0.499 1.52 PRS_PLINK_5e.04 716 Other arthropathies Both 18 42 14 musculoskeletal darkolivegreen 42, 18 11, 5 10, 6 10, 2 11, 5 -0.557 0.403 0.167 0.778 0.573 0.248 1.17 -0.507 1 0.612 0.213 0.602 0.0773 5.51 -1.5 1.45 0.301 0.521 0.223 0.00964 2.29 -0.943 1.08 0.381 0.419 0.389 0.0412 2.38 PRS_PLINK_5e.04 716.1 Unspecified polyarthropathy or polyarthritis Both 1 0 14 musculoskeletal darkolivegreen 0, 1 PRS_PLINK_5e.04 716.9 Arthropathy NOS Both 18 42 14 musculoskeletal darkolivegreen 42, 18 11, 5 10, 6 10, 2 11, 5 -0.557 0.403 0.167 0.778 0.573 0.248 1.17 -0.507 1 0.612 0.213 0.602 0.0773 5.51 -1.5 1.45 0.301 0.521 0.223 0.00964 2.29 -0.943 1.08 0.381 0.419 0.389 0.0412 2.38 PRS_PLINK_5e.04 717 Polymyalgia Rheumatica Both 1 3 14 musculoskeletal darkolivegreen 3, 1 1, 1 1, 0 1, 0 1, 1 0.364 14400 1 0 1.44 0.108 12.6 -0.0255 108 1 0 0.975 0.934 1.19 -0.088 202 1 0 0.916 0.714 1.26 PRS_PLINK_5e.04 720 Spinal stenosis Both 1 28 14 musculoskeletal darkolivegreen 28, 1 7, 1 7, 0 7, 0 7, 0 -0.407 0.672 0.545 0.263 0.666 0.072 2.58 -0.959 2.26 0.671 0.173 0.383 0.0021 19.5 -0.205 2.22 0.926 0.033 0.814 0.00451 1520 -1.43 2.54 0.575 0.24 0.24 9.55e-05 16 PRS_PLINK_5e.04 720.1 Spinal stenosis of lumbar region Both 0 24 14 musculoskeletal darkolivegreen 24, 0 6 6 6 6 PRS_PLINK_5e.04 721 Spondylosis and allied disorders Both 8 42 14 musculoskeletal darkolivegreen 42, 8 11, 3 10, 4 10, 0 11, 1 -0.728 0.571 0.202 0.695 0.483 0.109 1.47 0.221 1.07 0.837 0.077 1.25 0.161 10.9 -0.348 1.4 0.803 0.095 0.706 7.86e-07 9.57 -2.41 1.98 0.223 0.653 0.0898 0.00178 2.47 PRS_PLINK_5e.04 721.1 Spondylosis without myelopathy Both 7 41 14 musculoskeletal darkolivegreen 41, 7 11, 3 10, 3 10, 0 10, 1 -0.797 0.595 0.181 0.743 0.451 0.092 1.47 -0.308 1.18 0.795 0.1 0.735 0.045 7.45 -0.731 1.33 0.582 0.235 0.481 0.0078 4.92 -1.85 1.82 0.31 0.509 0.157 1.36e-12 3.98 PRS_PLINK_5e.04 721.2 Spondylosis with myelopathy Both 0 6 14 musculoskeletal darkolivegreen 6, 0 2 1 1 2 PRS_PLINK_5e.04 721.8 Other allied disorders of spine Both 1 4 14 musculoskeletal darkolivegreen 4, 1 1, 1 1, 0 1, 0 1, 0 -0.0152 398 1 0 0.985 0.691 1.22 -0.0146 87.3 1 0 0.985 0.834 1.1 0.00217 5.84 1 0 1 0.976 1.01 -0.00389 10.7 1 0 0.996 0.917 1.08 PRS_PLINK_5e.04 722 Intervertebral disc disorders Both 4 48 14 musculoskeletal darkolivegreen 48, 4 12, 0 12, 3 12, 0 12, 1 -0.216 0.609 0.723 0.141 0.806 0.0585 6.19 0.841 1.4 0.547 0.262 2.32 0.143 195 -0.388 1.74 0.823 0.085 0.678 0.00493 445 PRS_PLINK_5e.04 722.1 Displacement of intervertebral disc Both 1 39 14 musculoskeletal darkolivegreen 39, 1 10, 0 10, 1 9, 0 10, 0 -0.212 0.589 0.719 0.143 0.809 0.139 3.94 0.655 1.55 0.672 0.172 1.93 0.0716 165 PRS_PLINK_5e.04 722.6 Degeneration of intervertebral disc Both 3 35 14 musculoskeletal darkolivegreen 35, 3 9, 1 9, 1 8, 0 9, 1 -0.471 0.658 0.475 0.324 0.625 0.07 4.35 0.89 1.82 0.625 0.204 2.44 0.101 592 0.221 1.61 0.891 0.05 1.25 0.0224 377 -1.38 1.94 0.476 0.322 0.25 0.00261 53.8 PRS_PLINK_5e.04 722.7 Intervertebral disc disorder with myelopathy Both 0 6 14 musculoskeletal darkolivegreen 6, 0 2 1 1 2 PRS_PLINK_5e.04 722.8 Postlaminectomy syndrome Both 1 9 14 musculoskeletal darkolivegreen 9, 1 3, 1 2, 0 2, 0 2, 0 2.53 4.49 0.573 0.242 12.5 0.0448 417 0.471 45100 1 0 1.6 0.176 2.26 0.0493 381 1 0 1.05 0.666 1.79 0.0183 4030 1 0 1.02 0.535 1.94 PRS_PLINK_5e.04 722.9 Other and unspecified disc disorder Both 1 27 14 musculoskeletal darkolivegreen 27, 1 7, 1 7, 0 6, 0 7, 0 -0.0677 0.763 0.929 0.032 0.935 0.0975 8.73 -0.0943 2.41 0.969 0.014 0.91 0.00487 210 0.619 1.75 0.724 0.14 1.86 0.0541 383 0.189 2.2 0.932 0.031 1.21 0.00634 804 PRS_PLINK_5e.04 723 Other disorders of cervical region Both 2 14 14 musculoskeletal darkolivegreen 14, 2 4, 1 3, 1 3, 0 4, 0 0.282 1.02 0.781 0.107 1.33 0.176 182 0.944 5.69 0.868 0.061 2.57 2.54 2.6 0.0183 149 1 0 1.02 0.0829 12.5 0.198 40.7 0.996 0.002 1.22 0.442 3.26 PRS_PLINK_5e.04 723.1 Torticollis Both 0 6 14 musculoskeletal darkolivegreen 6, 0 2 1 1 2 PRS_PLINK_5e.04 724 Other and unspecified disorders of back Both 4 40 14 musculoskeletal darkolivegreen 40, 4 10, 1 10, 2 10, 0 10, 1 -0.282 0.53 0.595 0.226 0.754 0.123 2.22 0.267 1.19 0.823 0.085 1.31 0.0744 17.5 -0.33 1.64 0.841 0.075 0.719 0.0107 260 -1.1 1.88 0.56 0.252 0.333 9.64e-05 94 PRS_PLINK_5e.04 724.1 Disorders of sacrum Both 3 31 14 musculoskeletal darkolivegreen 31, 3 8, 2 8, 0 7, 0 8, 1 -0.169 0.609 0.782 0.107 0.845 0.0875 3.21 -0.5 1.6 0.754 0.122 0.607 0.000137 12.2 -0.798 1.92 0.677 0.169 0.45 0.000119 24.3 -1.6 1.88 0.395 0.403 0.202 0.000925 4.47 PRS_PLINK_5e.04 724.2 Disorders of coccyx Both 0 7 14 musculoskeletal darkolivegreen 7, 0 2 2 1 2 PRS_PLINK_5e.04 724.8 Other symptoms referable to back Both 0 14 14 musculoskeletal darkolivegreen 14, 0 4 3 3 4 PRS_PLINK_5e.04 724.9 Other unspecified back disorders Both 2 15 14 musculoskeletal darkolivegreen 15, 2 4, 0 4, 2 3, 0 4, 0 -0.027 0.918 0.977 0.01 0.973 0.168 37.7 2.2 3.3 0.506 0.296 8.99 0.14 3710 PRS_PLINK_5e.04 726 Peripheral enthesopathies and allied syndromes Both 23 23 14 musculoskeletal darkolivegreen 23, 23 5, 3 6, 6 5, 7 6, 7 0.455 0.431 0.291 0.536 1.58 0.718 5.02 1.43 1.33 0.281 0.551 4.19 0.549 193 1.74 1.52 0.252 0.598 5.67 0.485 397 0.81 1.21 0.501 0.3 2.25 0.333 19.6 PRS_PLINK_5e.04 726.1 Enthesopathy Both 18 23 14 musculoskeletal darkolivegreen 23, 18 5, 2 6, 5 5, 5 6, 6 0.537 0.458 0.241 0.617 1.71 0.742 6.09 1.44 1.52 0.342 0.465 4.22 0.387 695 1.88 1.72 0.276 0.559 6.53 0.242 249 0.781 1.44 0.589 0.23 2.18 0.14 29.7 PRS_PLINK_5e.04 726.2 Synoviopathy Both 2 6 14 musculoskeletal darkolivegreen 6, 2 2, 0 1, 0 1, 1 2, 1 0.251 2690000 1 0 1.29 0.146 5.06 0.178 5160 1 0 1.19 0.623 2.03 0.249 4230 1 0 1.28 0.287 9.55 PRS_PLINK_5e.04 726.3 Bursitis Both 5 10 14 musculoskeletal darkolivegreen 10, 5 3, 1 2, 0 2, 2 3, 2 0.162 1.19 0.892 0.05 1.18 0.0559 8.04 -0.0417 1470 1 0 0.959 0.143 4.62 1.14 264000 1 0 3.11 2.09 3.44 0.012 25.6 1 0 1.01 0.963 1.08 PRS_PLINK_5e.04 726.4 Calcaneal spur; Exostosis NOS Both 4 8 14 musculoskeletal darkolivegreen 8, 4 2, 1 2, 0 2, 1 2, 2 0.211 1.27 0.868 0.061 1.23 0.144 97.9 -0.228 1800 1 0 0.796 0.772 2.28 0.107 2140 1 0 1.11 0.696 1.24 -0.645 1e+07 1 0 0.525 0.00109 877 PRS_PLINK_5e.04 727 Other disorders of synovium, tendon, and bursa Both 25 22 14 musculoskeletal darkolivegreen 22, 25 6, 3 5, 5 5, 10 6, 7 0.582 0.437 0.183 0.738 1.79 0.813 4.54 0.646 1.45 0.656 0.183 1.91 0.0249 236 1.58 1.3 0.223 0.651 4.86 0.556 677 0.471 1.15 0.683 0.166 1.6 0.235 12.4 PRS_PLINK_5e.04 727.1 Synovitis and tenosynovitis Both 11 17 14 musculoskeletal darkolivegreen 17, 11 5, 2 4, 2 4, 2 4, 5 1.15 0.687 0.0934 1.03 3.17 0.957 19.9 0.536 2.63 0.839 0.076 1.71 0.0142 273000 -4.7 13.7 0.732 0.136 0.00909 0.00579 0.0148 0.476 1.61 0.767 0.115 1.61 0.0539 149 PRS_PLINK_5e.04 727.2 Bursitis disorders Both 0 2 14 musculoskeletal darkolivegreen 2, 0 1 1 1 1 PRS_PLINK_5e.04 727.4 Ganglion and cyst of synovium, tendon, and bursa Both 2 8 14 musculoskeletal darkolivegreen 8, 2 2, 0 2, 0 2, 0 2, 2 -0.446 1.89 0.813 0.09 0.64 0.0292 8.36 0.556 1550 1 0 1.74 0.711 5.02 PRS_PLINK_5e.04 727.5 Rupture of synovium Both 1 1 14 musculoskeletal darkolivegreen 1, 1 0.296 56.6 0.996 0.002 1.34 0.636 752 PRS_PLINK_5e.04 727.6 Rupture of tendon, nontraumatic Both 8 12 14 musculoskeletal darkolivegreen 12, 8 3, 0 3, 2 3, 2 3, 4 0.147 1.12 0.895 0.048 1.16 0.0974 14.7 -0.0801 144 1 0 0.923 0.481 6.68 0.525 80.6 0.995 0.002 1.69 4.58 3.87 -3.78 851 0.996 0.002 0.0229 0.299 0.655 PRS_PLINK_5e.04 727.7 Contracture of tendon (sheath) Both 0 4 14 musculoskeletal darkolivegreen 4, 0 1 1 1 1 PRS_PLINK_5e.04 727.8 Plica syndrome Both 3 0 14 musculoskeletal darkolivegreen 0, 3 PRS_PLINK_5e.04 728 Disorders of muscle, ligament, and fascia Both 9 20 14 musculoskeletal darkolivegreen 20, 9 5, 0 5, 4 5, 2 5, 3 -0.101 0.826 0.902 0.045 0.904 0.133 5.17 2.26 2.81 0.421 0.376 9.57 0.164 77700 -1.15 3.95 0.771 0.113 0.316 9.75e-05 1000 -0.226 3.4 0.947 0.024 0.798 0.000309 2410 PRS_PLINK_5e.04 728.2 Laxity of ligament or hypermobility syndrome Both 1 1 14 musculoskeletal darkolivegreen 1, 1 -0.0116 75.5 1 0 0.988 0.738 5.03 PRS_PLINK_5e.04 728.7 Fasciitis Both 11 14 14 musculoskeletal darkolivegreen 14, 11 4, 0 3, 2 3, 3 4, 6 0.103 0.874 0.906 0.043 1.11 0.143 5.41 1.31 15.3 0.932 0.031 3.71 3.61 23.8 0.569 1050000 1 0 1.77 1.34 2.39 0.937 3.53 0.791 0.102 2.55 0.000823 5170 PRS_PLINK_5e.04 728.71 Contracture of palmar fascia [Dupuytren's disease] Both 1 2 14 musculoskeletal darkolivegreen 2, 1 1, 0 0, 1 1, 0 1, 0 -0.000289 66.6 1 0 1 0.946 1.06 -0.00718 73.1 1 0 0.993 0.892 1.23 PRS_PLINK_5e.04 729 Other disorders of soft tissues Both 10 20 14 musculoskeletal darkolivegreen 20, 10 5, 2 5, 2 5, 2 5, 4 0.168 0.488 0.731 0.136 1.18 0.521 2.78 0.415 2.82 0.883 0.054 1.51 0.0143 98.2 0.768 2.17 0.724 0.14 2.15 0.0612 327 -0.115 1.8 0.949 0.023 0.892 0.0295 97 PRS_PLINK_5e.04 729.7 Nontraumatic compartment syndrome Both 0 1 14 musculoskeletal darkolivegreen 1, 0 PRS_PLINK_5e.04 731 Osteitis deformans and osteopathies associated with other disorders classified elsewhere Both 0 8 14 musculoskeletal darkolivegreen 8, 0 2 2 2 2 PRS_PLINK_5e.04 732 Osteochondropathies Both 1 4 14 musculoskeletal darkolivegreen 4, 1 1, 1 1, 0 1, 0 1, 0 0.0063 42 1 0 1.01 0.148 4.22 0.00313 12.4 1 0 1 0.946 1.08 -0.00175 11.1 1 0 0.998 0.947 1.03 0.00554 21.5 1 0 1.01 0.947 1.09 PRS_PLINK_5e.04 732.1 Juvenile osteochondrosis Both 1 0 14 musculoskeletal darkolivegreen 0, 1 PRS_PLINK_5e.04 732.7 Osteochondritis dissecans Both 0 2 14 musculoskeletal darkolivegreen 2, 0 1 1 1 1 PRS_PLINK_5e.04 733 Other disorders of bone and cartilage Both 5 30 14 musculoskeletal darkolivegreen 30, 5 8, 1 7, 0 7, 1 8, 3 0.304 0.654 0.642 0.192 1.36 0.116 5.36 -1.24 1.92 0.519 0.285 0.29 4.08e-07 6.68 0.436 1.77 0.806 0.094 1.55 0.0333 104 0.0181 1.58 0.991 0.004 1.02 0.0191 15.8 PRS_PLINK_5e.04 733.2 Cyst of bone Both 0 2 14 musculoskeletal darkolivegreen 2, 0 1 1 1 1 PRS_PLINK_5e.04 733.4 Aseptic necrosis of bone Both 1 5 14 musculoskeletal darkolivegreen 5, 1 2, 1 1, 0 1, 0 1, 0 0.0154 3140 1 0 1.02 0.501 2.24 0.0709 86300 1 0 1.07 3.75e-07 21.6 0.0297 35300 1 0 1.03 0.00342 3.8 0.272 1e+05 1 0 1.31 0.00118 365 PRS_PLINK_5e.04 733.6 Costochondritis Both 1 2 14 musculoskeletal darkolivegreen 2, 1 1, 0 0, 1 1, 0 1, 0 -0.49 9610 1 0 0.613 0.324 2.65 -0.00391 37.7 1 0 0.996 0.935 1.07 PRS_PLINK_5e.04 733.8 Malunion and nonunion of fracture Both 0 12 14 musculoskeletal darkolivegreen 12, 0 3 3 3 3 PRS_PLINK_5e.04 735 Acquired foot deformities Both 11 35 14 musculoskeletal darkolivegreen 35, 11 9, 2 9, 0 8, 4 9, 5 0.537 0.503 0.286 0.544 1.71 0.685 5.03 -0.272 1.56 0.862 0.065 0.762 0.00137 38.9 2.37 1.73 0.171 0.767 10.7 0.697 7990 2.25 1.98 0.256 0.592 9.47 0.111 1.45e+10 PRS_PLINK_5e.04 735.1 Flat foot Both 2 14 14 musculoskeletal darkolivegreen 14, 2 4, 1 3, 0 3, 0 4, 1 0.365 1.32 0.783 0.106 1.44 0.0591 70 -0.327 43.7 0.994 0.003 0.721 0.289 0.791 -0.39 6230000 1 0 0.677 0.000356 1200 -0.668 13400000 1 0 0.513 1.82e-06 2520 PRS_PLINK_5e.04 735.2 Acquired toe deformities Both 3 25 14 musculoskeletal darkolivegreen 25, 3 7, 0 6, 0 6, 0 6, 3 0.934 0.833 0.262 0.582 2.54 0.512 161 0.56 1.49 0.707 0.151 1.75 0.0627 48.1 PRS_PLINK_5e.04 735.21 Hammer toe (acquired) Both 3 21 14 musculoskeletal darkolivegreen 21, 3 6, 0 5, 0 5, 0 5, 3 0.809 0.818 0.323 0.491 2.25 0.535 27.7 0.207 1.85 0.911 0.041 1.23 0.0177 46.6 PRS_PLINK_5e.04 735.23 Hallux rigidus Both 0 8 14 musculoskeletal darkolivegreen 8, 0 2 2 2 2 PRS_PLINK_5e.04 735.3 Hallux valgus (Bunion) Both 6 26 14 musculoskeletal darkolivegreen 26, 6 7, 0 6, 0 6, 3 7, 3 0.557 1.01 0.581 0.236 1.75 0.178 16 0.883 1.75 0.614 0.212 2.42 0.122 747 0.907 2.23 0.684 0.165 2.48 0.00805 22900 PRS_PLINK_5e.04 736 Other acquired deformities of limbs Both 7 34 14 musculoskeletal darkolivegreen 34, 7 8, 1 8, 0 8, 2 9, 4 0.687 0.78 0.378 0.422 1.99 0.299 19.4 -0.0203 2 0.992 0.004 0.98 0.00216 107 0.592 2.04 0.772 0.112 1.81 0.0245 1660 1.47 1.69 0.384 0.415 4.36 0.0358 55900 PRS_PLINK_5e.04 736.2 Acquired deformities of finger Both 1 5 14 musculoskeletal darkolivegreen 5, 1 2, 0 1, 0 1, 0 1, 1 -0.498 1660 1 0 0.608 8.27e-05 557 3.22 9.55e+08 1 0 25.1 1.03e-17 1.51e+21 PRS_PLINK_5e.04 736.4 Genu valgum or varum (acquired) Both 0 1 14 musculoskeletal darkolivegreen 1, 0 PRS_PLINK_5e.04 736.6 Unequal leg length (acquired) Both 0 6 14 musculoskeletal darkolivegreen 6, 0 2 1 1 2 PRS_PLINK_5e.04 737 Curvature of spine Both 2 18 14 musculoskeletal darkolivegreen 18, 2 4, 0 4, 0 4, 0 5, 2 0.673 0.675 0.318 0.497 1.96 0.647 8.32 -1.91 5.91 0.747 0.127 0.149 9.56e-06 1110 PRS_PLINK_5e.04 737.1 Kyphosis (acquired) Both 1 7 14 musculoskeletal darkolivegreen 7, 1 1, 0 2, 0 1, 0 2, 1 -0.256 387 0.999 0 0.774 0.179 0.955 0.0119 390 1 0 1.01 0.859 1.19 PRS_PLINK_5e.04 737.2 Lordosis (acquired) Both 0 1 14 musculoskeletal darkolivegreen 1, 0 PRS_PLINK_5e.04 737.3 Kyphoscoliosis and scoliosis Both 1 13 14 musculoskeletal darkolivegreen 13, 1 3, 0 3, 0 3, 0 3, 1 0.553 1.17 0.635 0.197 1.74 0.0443 16 0.0522 2990 1 0 1.05 0.24 2.72 PRS_PLINK_5e.04 738 Other acquired musculoskeletal deformity Both 3 24 14 musculoskeletal darkolivegreen 24, 3 6, 0 6, 1 6, 0 6, 2 0.795 0.895 0.375 0.427 2.21 0.0235 196 -0.307 1.81 0.865 0.063 0.736 0.0321 113 -0.581 1.88 0.757 0.121 0.56 0.49 20.8 PRS_PLINK_5e.04 738.4 Acquired spondylolisthesis Both 0 12 14 musculoskeletal darkolivegreen 12, 0 3 3 3 3 PRS_PLINK_5e.04 739 Contracture of joint Both 2 10 14 musculoskeletal darkolivegreen 10, 2 3, 0 2, 0 2, 0 3, 2 0.106 1.3 0.935 0.029 1.11 0.0932 140 0.0525 359 1 0 1.05 0.847 1.41 PRS_PLINK_5e.04 740 Osteoarthrosis Both 23 40 14 musculoskeletal darkolivegreen 40, 23 10, 6 10, 7 10, 5 10, 5 -0.301 0.339 0.375 0.426 0.74 0.379 1.35 -0.486 0.999 0.627 0.203 0.615 0.0717 4.21 0.215 0.919 0.815 0.089 1.24 0.241 6.78 -0.909 1.04 0.384 0.415 0.403 0.0398 2.29 PRS_PLINK_5e.04 740.1 Osteoarthritis; localized Both 12 30 14 musculoskeletal darkolivegreen 30, 12 8, 4 7, 3 7, 2 8, 3 -0.64 0.467 0.171 0.768 0.527 0.201 1.18 -0.226 1.11 0.839 0.076 0.798 0.0667 5.74 -0.503 1.48 0.734 0.134 0.604 0.00393 6.86 -1.01 1.34 0.45 0.347 0.364 0.0313 3.21 PRS_PLINK_5e.04 740.11 Osteoarthrosis, localized, primary Both 9 29 14 musculoskeletal darkolivegreen 29, 9 8, 4 7, 2 7, 2 7, 1 -1.39 0.679 0.041 1.387 0.25 0.0394 0.77 -0.908 1.2 0.45 0.346 0.403 0.0172 2.79 -0.274 1.57 0.862 0.065 0.76 0.0256 14 -1.76 1.81 0.333 0.478 0.173 2.74e-05 3.15 PRS_PLINK_5e.04 740.12 Osteoarthrosis, localized, secondary Both 1 3 14 musculoskeletal darkolivegreen 3, 1 1, 1 1, 0 1, 0 1, 1 -1.55e-05 864 1 0 1 0.645 1.48 -0.0134 112 1 0 0.987 0.8 1.19 -0.00393 105 1 0 0.996 0.851 1.14 PRS_PLINK_5e.04 740.2 Osteoarthrosis, generalized Both 4 10 14 musculoskeletal darkolivegreen 10, 4 3, 0 2, 3 2, 0 3, 1 0.107 1.28 0.933 0.03 1.11 0.0638 8.88 1.85 5110000 1 0 6.35 1.19 19.1 -0.0648 1190 1 0 0.937 0.347 1.87 PRS_PLINK_5e.04 740.3 Osteoarthrosis involving more than one site, but not specified as generalized Both 2 1 14 musculoskeletal darkolivegreen 1, 2 0.106 2470 1 0 1.11 0.789 1.23 PRS_PLINK_5e.04 740.9 Osteoarthrosis NOS Both 23 40 14 musculoskeletal darkolivegreen 40, 23 10, 6 10, 7 10, 5 10, 5 -0.301 0.339 0.375 0.426 0.74 0.379 1.35 -0.486 0.999 0.627 0.203 0.615 0.0717 4.21 0.215 0.919 0.815 0.089 1.24 0.241 6.78 -0.909 1.04 0.384 0.415 0.403 0.0398 2.29 PRS_PLINK_5e.04 741 Symptoms and disorders of the joints Both 15 46 14 musculoskeletal darkolivegreen 46, 15 11, 2 11, 3 11, 5 12, 5 0.178 0.32 0.578 0.238 1.19 0.658 2.18 0.337 1.02 0.742 0.129 1.4 0.23 9.14 0.621 1.04 0.55 0.26 1.86 0.297 16 0.326 1.02 0.749 0.126 1.39 0.219 10.5 PRS_PLINK_5e.04 741.1 Ankylosis of joint Both 1 3 14 musculoskeletal darkolivegreen 3, 1 1, 0 1, 0 1, 1 1, 0 0.0483 1950 1 0 1.05 0.811 1.1 0.00546 98.8 1 0 1.01 0.976 1.06 PRS_PLINK_5e.04 741.2 Stiffness of joint Both 2 17 14 musculoskeletal darkolivegreen 17, 2 5, 1 4, 0 4, 0 4, 1 -0.201 1.14 0.86 0.065 0.818 0.0141 143 -1.57 46.8 0.973 0.012 0.207 0.182 0.242 -1.05 2.6 0.687 0.163 0.35 0.0063 13.4 -0.242 19 0.99 0.004 0.785 3.03e-07 1940000 PRS_PLINK_5e.04 741.3 Difficulty in walking Both 1 23 14 musculoskeletal darkolivegreen 23, 1 5, 0 6, 0 5, 0 6, 1 0.0848 0.801 0.916 0.038 1.09 0.112 30.8 0.0591 2.21 0.979 0.009 1.06 0.0409 1030 PRS_PLINK_5e.04 741.4 Joint effusions Both 9 32 14 musculoskeletal darkolivegreen 32, 9 7, 1 8, 1 8, 4 8, 3 -0.0927 0.417 0.824 0.084 0.912 0.414 1.94 -0.111 1.77 0.95 0.022 0.895 0.00821 23.2 0.888 1.46 0.542 0.266 2.43 0.178 42.7 2.03 2.26 0.369 0.433 7.62 0.136 12200 PRS_PLINK_5e.04 741.5 Hemarthrosis Both 1 2 14 musculoskeletal darkolivegreen 2, 1 1, 0 1, 1 1, 0 1, 1 7.8 21900 1 0 2450 8.24e-15 2.19e+32 -0.00895 46.6 1 0 0.991 0.935 1.05 PRS_PLINK_5e.04 741.6 Villonodular synovitis Both 1 1 14 musculoskeletal darkolivegreen 1, 1 0.00175 351 1 0 1 0.977 1.05 PRS_PLINK_5e.04 742 Derangement of joint, non-traumatic Both 7 45 14 musculoskeletal darkolivegreen 45, 7 11, 0 11, 5 11, 1 11, 1 -0.427 0.507 0.399 0.399 0.652 0.178 1.71 1.75 1.3 0.178 0.75 5.77 0.688 1210 0.271 1.41 0.848 0.072 1.31 0.0162 94.8 -0.235 1.49 0.875 0.058 0.79 0.00307 214 PRS_PLINK_5e.04 742.1 Loose body in joint Both 1 3 14 musculoskeletal darkolivegreen 3, 1 1, 0 1, 1 1, 0 1, 0 1.51 9870 1 0 4.54 0.02 240000 0.197 1950 1 0 1.22 0.576 7.85 PRS_PLINK_5e.04 742.2 Pathological, developmental or recurrent dislocation Both 0 3 14 musculoskeletal darkolivegreen 3, 0 1 1 1 1 PRS_PLINK_5e.04 742.8 Articular cartilage disorder Both 1 5 14 musculoskeletal darkolivegreen 5, 1 2, 0 1, 0 1, 1 1, 0 -0.0612 323 1 0 0.941 0.557 1.66 -0.00609 57.7 1 0 0.994 0.936 1.04 PRS_PLINK_5e.04 742.9 Other derangement of joint Both 5 43 14 musculoskeletal darkolivegreen 43, 5 10, 0 11, 4 10, 0 11, 1 -0.305 0.549 0.578 0.238 0.737 0.165 2.26 1.34 1.22 0.271 0.566 3.82 0.498 119 -0.47 1.58 0.766 0.116 0.625 0.00296 941 PRS_PLINK_5e.04 743 Osteoporosis, osteopenia and pathological fracture Both 12 51 14 musculoskeletal darkolivegreen 51, 12 12, 2 13, 4 12, 4 13, 2 -0.11 0.423 0.795 0.1 0.896 0.348 2.07 0.615 1.1 0.576 0.24 1.85 0.249 110 0.795 1.1 0.468 0.329 2.21 0.288 35.7 -0.706 1.35 0.602 0.221 0.494 1.61e-07 9.03 PRS_PLINK_5e.04 743.1 Osteoporosis Both 6 22 14 musculoskeletal darkolivegreen 22, 6 6, 3 5, 0 5, 1 6, 2 -0.219 0.554 0.692 0.16 0.803 0.269 2.26 -0.218 2.24 0.922 0.035 0.804 0.00421 66.4 -0.406 1.8 0.822 0.085 0.666 0.00456 9.36 -0.766 2.33 0.742 0.13 0.465 2.58e-05 256 PRS_PLINK_5e.04 743.11 Osteoporosis NOS Both 6 21 14 musculoskeletal darkolivegreen 21, 6 6, 3 5, 0 5, 1 5, 2 -0.219 0.554 0.692 0.16 0.803 0.269 2.26 -0.378 2.29 0.869 0.061 0.685 0.000497 18400 -0.419 1.73 0.809 0.092 0.657 0.00294 9.44 2 3.05 0.512 0.291 7.38 1.58e-05 1500000 PRS_PLINK_5e.04 743.12 Senile osteoporosis Both 0 4 14 musculoskeletal darkolivegreen 4, 0 1 1 1 1 PRS_PLINK_5e.04 743.13 Other specified osteoporosis Both 3 4 14 musculoskeletal darkolivegreen 4, 3 1, 1 1, 0 1, 1 1, 1 -0.125 218 1 0 0.882 0.224 3.97 0.00414 34.2 1 0 1 0.986 1.04 8.18 3.52e+08 1 0 3590 1.26e-11 9.73e+18 0.0526 25800 1 0 1.05 0.378 3.64 PRS_PLINK_5e.04 743.2 Pathologic fracture Both 2 8 14 musculoskeletal darkolivegreen 8, 2 2, 1 2, 0 2, 1 2, 0 0.354 2.43 0.884 0.053 1.43 0.0222 74.9 0.0513 34700 1 0 1.05 0.301 16200 0.265 2900 1 0 1.3 0.419 1.52 0.152 7190 1 0 1.16 0.246 2.46 PRS_PLINK_5e.04 743.21 Pathologic fracture of vertebrae Both 1 4 14 musculoskeletal darkolivegreen 4, 1 1, 1 1, 0 1, 0 1, 0 0.00306 797 1 0 1 0.858 1.39 -0.153 151 0.999 0 0.859 0.637 1.23 0.00232 310 1 0 1 0.844 1.14 0.00609 14.4 1 0 1.01 0.969 1.11 PRS_PLINK_5e.04 743.22 Pathologic fracture of femur Both 0 1 14 musculoskeletal darkolivegreen 1, 0 PRS_PLINK_5e.04 743.4 Stress fracture Both 2 6 14 musculoskeletal darkolivegreen 6, 2 2, 0 1, 0 1, 1 2, 1 0.0529 298 1 0 1.05 0.785 1.65 -0.00915 90.3 1 0 0.991 0.906 1.16 0.174 803 1 0 1.19 0.6 1.27 PRS_PLINK_5e.04 743.9 Osteopenia or other disorder of bone and cartilage Both 9 46 14 musculoskeletal darkolivegreen 46, 9 11, 1 11, 4 11, 3 12, 1 -0.118 0.433 0.785 0.105 0.889 0.343 2.09 0.981 1.25 0.432 0.364 2.67 0.316 59.7 0.656 1.26 0.602 0.22 1.93 0.0277 32.1 -0.47 1.33 0.723 0.141 0.625 0.00127 10 PRS_PLINK_5e.04 745 Pain in joint Both 42 22 14 musculoskeletal darkolivegreen 22, 42 5, 7 5, 10 5, 18 6, 7 0.148 0.32 0.643 0.192 1.16 0.637 2.13 0.426 1.11 0.702 0.154 1.53 0.163 85.7 0.441 0.89 0.62 0.208 1.55 0.292 7.78 -0.598 1.25 0.632 0.199 0.55 0.0334 4.57 PRS_PLINK_5e.04 747 Cardiac and circulatory congenital anomalies Both 3 23 15 congenital anomalies mediumspringgreen 23, 3 5, 1 6, 0 5, 0 6, 2 0.817 0.783 0.296 0.528 2.26 0.589 16.5 0.0157 2.28 0.994 0.002 1.02 0.00759 144 0.0145 12.4 0.999 0 1.01 5.18e-08 36300000 0.981 1.83 0.593 0.227 2.67 0.164 75.3 PRS_PLINK_5e.04 747.1 Cardiac congenital anomalies Both 3 17 15 congenital anomalies mediumspringgreen 17, 3 4, 0 4, 1 4, 0 4, 2 1.32 1.35 0.33 0.482 3.74 0.547 47600 0.209 4.09 0.959 0.018 1.23 0.928 1.83 -2.28 17.8 0.898 0.047 0.103 1.16e-07 185000 PRS_PLINK_5e.04 747.11 Cardiac shunt/ heart septal defect Both 1 9 15 congenital anomalies mediumspringgreen 9, 1 3, 0 2, 0 2, 1 2, 0 -2.45 54 0.964 0.016 0.0859 0.076 0.0969 -0.262 4150 1 0 0.769 0.537 2.21 PRS_PLINK_5e.04 747.12 Valvular heart disease/ heart chambers Both 2 4 15 congenital anomalies mediumspringgreen 4, 2 1, 0 1, 1 1, 1 1, 0 0.0409 246 1 0 1.04 0.312 3.15 PRS_PLINK_5e.04 747.13 Congenital anomalies of great vessels Both 0 3 15 congenital anomalies mediumspringgreen 3, 0 1 1 1 1 PRS_PLINK_5e.04 747.2 Congenital anomalies of peripheral vascular system Both 0 7 15 congenital anomalies mediumspringgreen 7, 0 2 2 1 2 PRS_PLINK_5e.04 748 Anomalies of respiratory system, congenital Both 0 3 15 congenital anomalies mediumspringgreen 3, 0 1 1 1 1 PRS_PLINK_5e.04 749 Congenital anomalies of face and neck Both 2 12 15 congenital anomalies mediumspringgreen 12, 2 3, 0 3, 1 3, 0 3, 1 0.0884 1.26 0.944 0.025 1.09 0.0473 25.7 4.94 36200000 1 0 140 2.31e-09 148000 -0.632 2830 1 0 0.532 0.00645 4.39 PRS_PLINK_5e.04 749.1 Cleft palate Both 0 2 15 congenital anomalies mediumspringgreen 2, 0 1 1 1 1 PRS_PLINK_5e.04 749.2 Congenital anomalies of skull and face bones Both 0 2 15 congenital anomalies mediumspringgreen 2, 0 1 1 1 1 PRS_PLINK_5e.04 750 Digestive congenital anomalies Both 2 13 15 congenital anomalies mediumspringgreen 13, 2 4, 2 3, 0 3, 0 3, 0 -1.05 1.86 0.571 0.243 0.349 0.0105 6.3 0.695 75.1 0.993 0.003 2 0.424 2.36 0.536 279 0.998 0.001 1.71 6.07 120 4.89 341 0.989 0.005 132 1.63 156000 PRS_PLINK_5e.04 750.1 Upper gastrointestinal congenital anomalies Both 0 4 15 congenital anomalies mediumspringgreen 4, 0 1 1 1 1 PRS_PLINK_5e.04 750.11 Esophageal atresia/tracheoesophageal fistula Both 0 2 15 congenital anomalies mediumspringgreen 2, 0 1 1 1 1 PRS_PLINK_5e.04 750.13 Congenital anomalies of mouth/tongue Both 0 2 15 congenital anomalies mediumspringgreen 2, 0 1 1 1 1 PRS_PLINK_5e.04 750.14 Congenital anomalies of esophagus Both 0 1 15 congenital anomalies mediumspringgreen 1, 0 PRS_PLINK_5e.04 750.2 Lower gastrointestinal congenital anomalies Both 2 11 15 congenital anomalies mediumspringgreen 11, 2 3, 2 3, 0 2, 0 3, 0 0.211 3.12 0.946 0.024 1.24 0.00244 307 -0.107 102 0.999 0 0.899 0.883 1.05 -2.42 1880 0.999 0 0.0892 0.00128 435 0.397 9710 1 0 1.49 0.409 2.53 PRS_PLINK_5e.04 750.21 Congenital anomalies of intestine Both 1 6 15 congenital anomalies mediumspringgreen 6, 1 2, 1 1, 0 1, 0 2, 0 -0.634 605 0.999 0 0.531 0.000135 392 -0.0714 5630 1 0 0.931 0.408 1.31 0.336 8450 1 0 1.4 0.335 2 3.7 232 0.987 0.006 40.5 1.6e-05 5.43e+09 PRS_PLINK_5e.04 750.22 Congenital anomaly of gallbladder, bile ducts, liver, pancreas Both 1 9 15 congenital anomalies mediumspringgreen 9, 1 3, 0 2, 1 2, 0 2, 0 -0.193 3.38 0.955 0.02 0.824 0.00202 123 -0.0684 2470 1 0 0.934 0.923 1.27 PRS_PLINK_5e.04 751 Genitourinary congenital anomalies Both 8 28 15 congenital anomalies mediumspringgreen 28, 8 6, 3 7, 2 7, 0 7, 3 0.116 0.438 0.792 0.102 1.12 0.497 2.7 -0.0864 1.87 0.963 0.016 0.917 0.0101 3650 -0.0921 1.63 0.955 0.02 0.912 0.0175 260 0.307 1.55 0.843 0.074 1.36 0.0938 20.7 PRS_PLINK_5e.04 751.1 Congenital anomalies of genital organs Both 3 5 15 congenital anomalies mediumspringgreen 5, 3 2, 0 1, 0 1, 1 1, 2 -0.0368 56.4 0.999 0 0.964 0.519 1.15 -0.0208 42.2 1 0 0.979 0.88 1.1 -0.277 6420 1 0 0.758 0.00169 139 PRS_PLINK_5e.04 751.11 Congenital anomalies of female genital organs Female 2 3 15 congenital anomalies mediumspringgreen 3, 2 1, 1 1, 0 1, 1 1, 1 0.178 2310 1 0 1.19 0.575 5.96 -1.26 23600 1 0 0.284 0.0294 16.4 -6.24 1.88e+08 1 0 0.00194 1.35e-20 1.37e+14 PRS_PLINK_5e.04 751.12 Congenital anomalies of male genital organs Male 0 4 15 congenital anomalies mediumspringgreen 4, 0 1 1 1 1 PRS_PLINK_5e.04 751.2 Congenital anomalies of urinary system Both 6 7 15 congenital anomalies mediumspringgreen 7, 6 2, 4 2, 0 1, 0 2, 2 0.223 1.56 0.886 0.052 1.25 0.00542 181 0.0102 3.92 0.998 0.001 1.01 0.00228 449 -0.142 1210 1 0 0.867 0.754 1.61 0.47 10 0.963 0.017 1.6 2.58e-06 298000 PRS_PLINK_5e.04 751.21 Cystic kidney disease Both 2 4 15 congenital anomalies mediumspringgreen 4, 2 1, 1 1, 0 1, 0 1, 1 -0.0151 1720000 1 0 0.985 0.327 2.67 -0.00515 90.5 1 0 0.995 0.935 1.09 0.0074 74.1 1 0 1.01 0.984 1.05 -0.481 7450 1 0 0.618 0.213 3.18 PRS_PLINK_5e.04 751.22 Other specified congenital anomalies of kidney Both 5 3 15 congenital anomalies mediumspringgreen 3, 5 1, 3 1, 0 1, 2 1, 3 0.0281 225 1 0 1.03 1 1.55 -0.0244 948 1 0 0.976 0.848 1.23 0.0227 135000 1 0 1.02 0.436 1.55 PRS_PLINK_5e.04 751.3 Obstructive genitourinary defect Both 1 4 15 congenital anomalies mediumspringgreen 4, 1 1, 1 1, 0 1, 0 1, 0 0.0456 2660 1 0 1.05 0.462 2.44 0.0209 348 1 0 1.02 0.809 1.49 -0.00813 239 1 0 0.992 0.812 1.2 0.00245 28.2 1 0 1 0.966 1.05 PRS_PLINK_5e.04 752 Nervous system congenital anomalies Both 1 15 15 congenital anomalies mediumspringgreen 15, 1 4, 1 4, 0 3, 0 4, 0 -0.36 0.947 0.703 0.153 0.697 8.54e-05 3.63 -0.211 8.71 0.981 0.008 0.81 0.769 0.817 -0.0615 780 1 0 0.94 0.103 8.13 -2.86 43.4 0.947 0.023 0.0571 0.0582 402 PRS_PLINK_5e.04 752.1 Neural tube defects Both 0 13 15 congenital anomalies mediumspringgreen 13, 0 4 3 3 3 PRS_PLINK_5e.04 752.11 Spina bifida Both 0 2 15 congenital anomalies mediumspringgreen 2, 0 1 1 1 1 PRS_PLINK_5e.04 752.2 Other specified congenital anomalies of nervous system Both 0 4 15 congenital anomalies mediumspringgreen 4, 0 1 1 1 1 PRS_PLINK_5e.04 753 Congenital anomalies of the eye Both 1 8 15 congenital anomalies mediumspringgreen 8, 1 2, 1 2, 0 2, 0 2, 0 -0.888 46.4 0.985 0.007 0.411 0.229 0.272 -0.00694 373 1 0 0.993 0.917 1.08 -0.469 12900 1 0 0.626 0.435 8.38 0.00963 43.7 1 0 1.01 0.94 1.05 PRS_PLINK_5e.04 753.1 Congenital cataract and lens anomalies Both 0 1 15 congenital anomalies mediumspringgreen 1, 0 PRS_PLINK_5e.04 753.2 Congenital anomalies of posterior segment of eye Both 0 3 15 congenital anomalies mediumspringgreen 3, 0 1 1 1 1 PRS_PLINK_5e.04 754 Congenital musculoskeletal deformities of spine Both 1 11 15 congenital anomalies mediumspringgreen 11, 1 3, 0 3, 0 2, 1 3, 0 0.95 1.87 0.611 0.214 2.59 0.181 4100 0.097 3940 1 0 1.1 0.541 1.22 PRS_PLINK_5e.04 754.1 Lumbosacral spondylolysis, congenital Both 1 2 15 congenital anomalies mediumspringgreen 2, 1 1, 0 0, 1 1, 0 1, 0 -0.0248 115 1 0 0.976 0.905 1.05 0.00316 221 1 0 1 0.979 1.04 PRS_PLINK_5e.04 754.2 Spondylolisthesis, congenital Both 0 5 15 congenital anomalies mediumspringgreen 5, 0 2 1 1 1 PRS_PLINK_5e.04 755 Congenital anomalies of limbs Both 1 14 15 congenital anomalies mediumspringgreen 14, 1 4, 0 3, 0 3, 0 4, 1 0.384 1.16 0.74 0.131 1.47 0.161 20.4 0.431 217 0.998 0.001 1.54 2.05e-09 7.28e+10 PRS_PLINK_5e.04 755.1 Congenital deformities of feet Both 1 9 15 congenital anomalies mediumspringgreen 9, 1 3, 0 2, 0 2, 0 2, 1 -3.15e-13 1.63 1 0 1 0.0822 10.6 0.0535 1500 1 0 1.05 0.38 3.17 PRS_PLINK_5e.04 755.6 Other congenital anomalies of lower limb, including pelvic girdle Both 0 4 15 congenital anomalies mediumspringgreen 4, 0 1 1 1 1 PRS_PLINK_5e.04 755.61 Congenital hip dysplasia and deformity Both 0 2 15 congenital anomalies mediumspringgreen 2, 0 1 1 1 1 PRS_PLINK_5e.04 756 Other congenital musculoskeletal anomalies Both 2 17 15 congenital anomalies mediumspringgreen 17, 2 4, 0 4, 2 4, 0 4, 0 -0.123 0.737 0.867 0.062 0.884 0.109 15.9 0.0883 168 1 0 1.09 0.000168 8220 PRS_PLINK_5e.04 756.2 Pectus and other congenital anomalies of ribs/sternum Both 0 1 15 congenital anomalies mediumspringgreen 1, 0 PRS_PLINK_5e.04 756.3 Congenital anomalies of muscle, tendon, fascia, and connective tissue Both 0 2 15 congenital anomalies mediumspringgreen 2, 0 1 1 1 1 PRS_PLINK_5e.04 756.5 Congenital osteodystrophies Both 1 11 15 congenital anomalies mediumspringgreen 11, 1 2, 0 3, 1 2, 0 3, 0 0.171 1.41 0.903 0.044 1.19 0.0642 12.5 0.702 6460 1 0 2.02 0.363 35.2 PRS_PLINK_5e.04 757 Congenital anomalies of the integument Both 1 4 15 congenital anomalies mediumspringgreen 4, 1 1, 0 1, 0 1, 0 1, 1 -0.249 7140 1 0 0.78 0.0468 3.88 -0.0142 50.1 1 0 0.986 0.91 1.07 PRS_PLINK_5e.04 758 Chromosomal anomalies and genetic disorders Both 1 2 15 congenital anomalies mediumspringgreen 2, 1 1, 1 1, 0 1, 1 1, 0 0.341 21500 1 0 1.41 0.326 2.31 0.241 13800 1 0 1.27 0.45 1.89 PRS_PLINK_5e.04 758.1 Chromosomal anomalies Both 1 0 15 congenital anomalies mediumspringgreen 0, 1 PRS_PLINK_5e.04 759 Other and unspecified congenital anomalies Both 0 3 15 congenital anomalies mediumspringgreen 3, 0 1 1 1 1 PRS_PLINK_5e.04 760 Back pain Both 25 39 17 symptoms purple 39, 25 9, 4 10, 8 9, 10 10, 3 -0.228 0.299 0.446 0.35 0.796 0.445 1.36 1.18 1.14 0.299 0.524 3.26 0.443 54 0.925 0.901 0.304 0.517 2.52 0.516 14 -1.38 1.39 0.321 0.494 0.252 1.66e-07 2.44 PRS_PLINK_5e.04 761 Cervicalgia Both 15 48 17 symptoms purple 48, 15 11, 1 12, 8 12, 3 12, 3 -0.0683 0.348 0.845 0.073 0.934 0.461 1.8 2.26 1.39 0.103 0.985 9.54 0.979 1950 0.593 1.39 0.668 0.175 1.81 0.0491 31.6 0.105 1.31 0.936 0.029 1.11 0.0239 37.2 PRS_PLINK_5e.04 763 Thoracic or lumbosacral neuritis or radiculitis, unspecified Both 2 39 17 symptoms purple 39, 2 10, 1 10, 1 9, 0 10, 0 -0.326 0.621 0.6 0.222 0.722 0.118 2.64 -0.205 1.28 0.872 0.059 0.815 0.0607 9.34 -0.245 1.45 0.866 0.062 0.783 0.00781 96.7 -1.08 1.93 0.575 0.24 0.34 3.32e-05 16.8 PRS_PLINK_5e.04 764 Sciatica Both 2 38 17 symptoms purple 38, 2 10, 2 9, 0 9, 0 10, 0 -0.428 0.704 0.543 0.265 0.652 0.0713 4.3 -2.08 1.9 0.274 0.562 0.125 3.67e-05 2.67 -1.67 1.97 0.395 0.403 0.188 6.78e-06 6.44 -1.35 1.96 0.492 0.308 0.26 1.53e-05 56.6 PRS_PLINK_5e.04 765 Cervical radiculitis Both 3 25 17 symptoms purple 25, 3 7, 1 6, 1 6, 0 6, 1 -0.589 0.896 0.511 0.292 0.555 0.0138 2.79 -0.574 1.69 0.733 0.135 0.563 8.49e-08 11.5 -2.31 3.4 0.498 0.303 0.0996 2.94e-05 20.9 -0.425 1.77 0.811 0.091 0.654 1.03e-06 13.7 PRS_PLINK_5e.04 766 Neuralgia, neuritis, and radiculitis NOS Both 6 48 17 symptoms purple 48, 6 12, 2 12, 2 12, 1 12, 1 -0.037 0.454 0.935 0.029 0.964 0.36 2.43 0.15 1.09 0.891 0.05 1.16 0.153 9.95 0.0444 1.16 0.969 0.013 1.05 0.108 11.8 -0.263 1.23 0.831 0.08 0.768 0.0179 7.89 PRS_PLINK_5e.04 767 Cervicocranial/Cervicobrachial syndrome Both 0 1 17 symptoms purple 1, 0 PRS_PLINK_5e.04 769 Nonallopathic lesions NEC Both 2 20 17 symptoms purple 20, 2 5, 0 5, 1 5, 0 5, 1 0.125 0.801 0.876 0.058 1.13 0.205 10.3 -0.0413 1400 1 0 0.96 0.437 1.43 0.208 22.7 0.993 0.003 1.23 2.51e-07 2840000 PRS_PLINK_5e.04 770 Myalgia and myositis unspecified Both 11 47 17 symptoms purple 47, 11 11, 6 12, 1 11, 2 12, 2 -0.339 0.449 0.451 0.346 0.713 0.271 1.67 -1.78 1.2 0.137 0.864 0.169 0.0124 1.43 -0.689 1.16 0.553 0.258 0.502 6e-05 4.38 -1.6 1.56 0.307 0.513 0.203 8.74e-09 2.68 PRS_PLINK_5e.04 771 Musculoskeletal symptoms referable to limbs Both 6 44 17 symptoms purple 44, 6 11, 3 11, 2 11, 0 11, 1 -0.582 0.63 0.356 0.449 0.559 0.0321 1.73 -1.4 1.34 0.295 0.53 0.247 0.00946 2.34 -0.484 1.63 0.766 0.116 0.616 0.00614 180 -0.707 1.58 0.655 0.184 0.493 0.00593 31.9 PRS_PLINK_5e.04 771.1 Swelling of limb Both 11 43 17 symptoms purple 43, 11 11, 3 11, 2 10, 1 11, 5 0.189 0.44 0.667 0.176 1.21 0.533 2.81 -0.628 1.11 0.57 0.244 0.534 0.0366 3.71 -0.284 1.21 0.814 0.089 0.753 0.0547 6.15 0.519 1.16 0.654 0.185 1.68 0.209 18.3 PRS_PLINK_5e.04 771.2 Cramp of limb Both 1 18 17 symptoms purple 18, 1 5, 0 4, 1 4, 0 5, 0 -0.0652 0.951 0.945 0.024 0.937 0.0406 27.5 0.0403 2.22 0.986 0.006 1.04 0.0441 1.55 PRS_PLINK_5e.04 772 Symptoms of the muscles Both 6 23 17 symptoms purple 23, 6 5, 0 6, 4 5, 0 6, 2 -0.256 0.717 0.721 0.142 0.774 0.111 3.57 -0.0437 1.74 0.98 0.009 0.957 0.891 1.17 2.37 3.82 0.535 0.272 10.7 0.0382 49000 PRS_PLINK_5e.04 772.1 Muscular wasting and disuse atrophy Both 1 9 17 symptoms purple 9, 1 3, 0 2, 0 2, 1 2, 0 -0.299 2.2 0.892 0.05 0.741 0.0227 15.5 -0.129 99.2 0.999 0 0.879 0.479 1.47 PRS_PLINK_5e.04 772.2 Spasm of muscle Both 3 31 17 symptoms purple 31, 3 8, 0 8, 1 7, 1 8, 1 -0.142 0.668 0.831 0.08 0.867 0.0878 3.31 0.774 1.45 0.592 0.227 2.17 0.188 2580 0.129 2.2 0.953 0.021 1.14 0.00543 679 0.899 1.77 0.612 0.214 2.46 0.0631 208 PRS_PLINK_5e.04 772.3 Muscle weakness Both 4 27 17 symptoms purple 27, 4 7, 1 7, 1 6, 1 7, 1 0.45 0.77 0.559 0.253 1.57 0.043 12.4 1.27 2.35 0.588 0.23 3.56 0.0183 11900 -0.559 1.91 0.77 0.114 0.572 0.00773 21.8 -0.118 1.66 0.943 0.025 0.888 0.00503 24.5 PRS_PLINK_5e.04 772.4 Rhabdomyolysis Both 2 0 17 symptoms purple 0, 2 PRS_PLINK_5e.04 772.6 Facial weakness Both 0 3 17 symptoms purple 3, 0 1 1 1 1 PRS_PLINK_5e.04 780 Hypothermia/Chills Both 1 8 17 symptoms purple 8, 1 2, 1 2, 0 2, 0 2, 0 -1.88 8.79 0.831 0.08 0.153 0.0296 0.797 -0.0512 460 1 0 0.95 0.944 1.03 0.117 783 1 0 1.12 0.871 1.57 -0.319 2760 1 0 0.727 0.664 1.51 PRS_PLINK_5e.04 781 Symptoms involving nervous and musculoskeletal systems Both 4 31 17 symptoms purple 31, 4 8, 0 8, 2 7, 2 8, 0 0.472 0.937 0.614 0.212 1.6 0.0298 1130 1.26 1.73 0.467 0.33 3.52 0.0934 477 0.82 1.65 0.62 0.207 2.27 0.0502 244000 PRS_PLINK_5e.04 782.3 Edema Both 12 40 17 symptoms purple 40, 12 10, 2 10, 3 10, 2 10, 5 0.546 0.417 0.191 0.72 1.73 0.82 3.92 -0.34 1.35 0.802 0.096 0.712 0.0291 8.99 1.71 1.69 0.313 0.505 5.54 0.32 4740000 0.252 1.16 0.828 0.082 1.29 0.097 13.1 PRS_PLINK_5e.04 782.6 Pallor and flushing Both 2 10 17 symptoms purple 10, 2 3, 1 2, 0 2, 1 3, 0 0.456 2.08 0.826 0.083 1.58 0.0371 277 -0.0319 1230 1 0 0.969 0.419 1.54 0.0867 621 1 0 1.09 0.573 3.7 0.0565 3330 1 0 1.06 0.305 5.61 PRS_PLINK_5e.04 783 Fever of unknown origin Both 10 52 17 symptoms purple 52, 10 12, 1 13, 3 13, 3 13, 3 0.264 0.351 0.452 0.345 1.3 0.652 2.59 1.38 1.59 0.386 0.414 3.98 0.221 5280 0.106 1.19 0.929 0.032 1.11 0.0736 20.9 1 1.27 0.431 0.366 2.73 0.218 119 PRS_PLINK_5e.04 785 Abdominal pain Both 30 34 17 symptoms purple 34, 30 8, 10 8, 7 8, 8 9, 5 -0.132 0.293 0.653 0.185 0.876 0.504 1.49 -1.29 1.09 0.237 0.626 0.274 0.0285 1.77 0.368 0.908 0.686 0.164 1.44 0.289 8.13 -0.698 1.1 0.527 0.278 0.498 0.0267 3.7 PRS_PLINK_5e.04 788 Syncope and collapse Both 5 49 17 symptoms purple 49, 5 13, 2 12, 2 12, 1 12, 0 -1.34 0.829 0.106 0.977 0.261 0.00545 1.31 -0.872 1.24 0.481 0.318 0.418 0.0181 4.86 -0.518 1.26 0.68 0.168 0.596 0.0262 7.64 -0.755 1.43 0.597 0.224 0.47 0.00675 6.13 PRS_PLINK_5e.04 789 Nausea and vomiting Both 18 46 17 symptoms purple 46, 18 11, 7 11, 4 11, 4 12, 3 -0.181 0.312 0.562 0.25 0.835 0.447 1.46 -1.69 1.29 0.188 0.725 0.184 0.00575 1.67 0.29 1.04 0.781 0.107 1.34 0.198 19.4 -0.939 1.04 0.367 0.436 0.391 0.0404 2.38 PRS_PLINK_5e.04 789.1 Persistent vomiting Both 2 10 17 symptoms purple 10, 2 3, 2 2, 0 2, 0 3, 0 -0.611 1.45 0.673 0.172 0.543 0.0181 4.65 0.142 1590 1 0 1.15 0.504 6.3 0.165 988 1 0 1.18 0.602 1.28 0.0601 916 1 0 1.06 0.519 4.27 PRS_PLINK_5e.04 790 Nonspecific findings on examination of blood Both 16 27 17 symptoms purple 27, 16 7, 6 7, 2 6, 5 7, 3 0.573 0.761 0.452 0.345 1.77 0.329 198 0.34 1.62 0.834 0.079 1.4 0.043 77.1 1.02 1.49 0.494 0.307 2.77 0.192 10500 1.01 1.54 0.511 0.292 2.75 0.157 6580 PRS_PLINK_5e.04 790.1 Elevated sedimentation rate Both 1 4 17 symptoms purple 4, 1 1, 0 1, 0 1, 1 1, 0 -0.0307 1260 1 0 0.97 0.28 3.68 -0.109 1850 1 0 0.897 0.433 1.26 PRS_PLINK_5e.04 790.6 Other abnormal blood chemistry Both 22 40 17 symptoms purple 40, 22 9, 5 10, 3 10, 8 10, 6 -0.00839 0.347 0.981 0.008 0.992 0.519 1.93 0.646 1.22 0.595 0.226 1.91 0.0923 66.3 0.437 0.939 0.641 0.193 1.55 0.291 9.03 -0.00219 1.04 0.998 0.001 0.998 0.138 7.05 PRS_PLINK_5e.04 790.8 Elevated C-reactive protein (CRP) Both 0 5 17 symptoms purple 5, 0 2 1 1 1 PRS_PLINK_5e.04 790.9 Abnormal arterial blood gases Both 0 2 17 symptoms purple 2, 0 1 1 1 1 PRS_PLINK_5e.04 791 Gangrene Both 0 13 17 symptoms purple 13, 0 4 3 3 3 PRS_PLINK_5e.04 792 Abnormal Papanicolaou smear of cervix and cervical HPV Female 6 15 11 genitourinary black 15, 6 4, 0 4, 2 3, 0 4, 4 2.75 1.6 0.0856 1.068 15.7 1.47 4490 1.09 10.9 0.921 0.036 2.96 2.68 3.27 3.35 2.99 0.262 0.582 28.6 0.518 10100 PRS_PLINK_5e.04 792.1 Papanicolaou smear of cervix or vagina with atypical squamous cells Female 4 7 11 genitourinary black 7, 4 2, 0 2, 0 1, 1 2, 3 1.44 1.66 0.388 0.411 4.21 0.403 94.8 -6.99 1.71e+08 1 0 0.000925 2.37e-17 3.83e+10 -0.0148 59.6 1 0 0.985 0.435 1.88 PRS_PLINK_5e.04 794 Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc) Both 0 5 17 symptoms purple 5, 0 2 1 1 1 PRS_PLINK_5e.04 795 Other and nonspecific abnormal cytological, histological and immunological findings Both 3 27 17 symptoms purple 27, 3 7, 0 7, 2 6, 0 7, 1 0.236 0.624 0.705 0.152 1.27 0.375 7.82 0.628 1.71 0.714 0.146 1.87 0.11 178 0.779 2.82 0.782 0.107 2.18 0.00226 1880 PRS_PLINK_5e.04 795.8 Abnormal tumor markers Both 1 13 17 symptoms purple 13, 1 4, 0 3, 0 3, 1 3, 0 0.374 0.935 0.689 0.162 1.45 0.221 11.8 0.377 639 1 0 1.46 0.349 5.54 PRS_PLINK_5e.04 795.81 Elevated carcinoembryonic antigen [CEA] Both 0 1 17 symptoms purple 1, 0 PRS_PLINK_5e.04 795.82 Elevated cancer antigen 125 [CA 125] Both 0 2 17 symptoms purple 2, 0 1 1 1 1 PRS_PLINK_5e.04 796 Elevated prostate specific antigen [PSA] Male 2 10 11 genitourinary black 10, 2 3, 0 2, 0 2, 2 3, 0 0.348 1.17 0.766 0.116 1.42 0.0417 24.1 0.389 1960 1 0 1.48 0.432 3.09 PRS_PLINK_5e.04 797 Shock Both 0 10 17 symptoms purple 10, 0 3 2 2 3 PRS_PLINK_5e.04 797.1 Cardiogenic shock Both 0 4 17 symptoms purple 4, 0 1 1 1 1 PRS_PLINK_5e.04 798 Malaise and fatigue Both 25 39 17 symptoms purple 39, 25 9, 7 10, 10 9, 3 10, 5 -0.184 0.326 0.572 0.243 0.832 0.438 1.51 -0.312 0.833 0.708 0.15 0.732 0.14 3.16 -0.169 1.04 0.871 0.06 0.845 0.129 5.01 -0.943 0.963 0.327 0.485 0.389 0.059 1.97 PRS_PLINK_5e.04 798.1 Chronic fatigue syndrome Both 4 20 17 symptoms purple 20, 4 5, 2 5, 0 5, 1 5, 1 -0.0515 0.774 0.947 0.024 0.95 0.185 5.35 -0.496 2.33 0.832 0.08 0.609 0.491 39.9 -0.95 1.91 0.62 0.208 0.387 0.000466 49.8 0.913 2.74 0.739 0.132 2.49 0.0108 763 PRS_PLINK_5e.04 800 Fracture of lower limb Both 6 28 18 injuries & poisonings gray50 28, 6 7, 1 7, 0 7, 4 7, 1 0.371 0.548 0.498 0.303 1.45 0.509 4.35 1.24 2.46 0.615 0.211 3.46 0.0489 28900 1.63 1.51 0.28 0.552 5.13 0.512 2180 -3.32 2.9 0.251 0.6 0.036 6.44e-07 3.52 PRS_PLINK_5e.04 800.1 Fracture of neck of femur Both 0 7 18 injuries & poisonings gray50 7, 0 2 2 1 2 PRS_PLINK_5e.04 800.2 Fracture of unspecified part of femur Both 2 3 18 injuries & poisonings gray50 3, 2 1, 0 1, 0 1, 2 1, 0 0.138 2440 1 0 1.15 0.716 2.96 0.253 5550 1 0 1.29 0.556 8.72 PRS_PLINK_5e.04 800.3 Fracture of tibia and fibula Both 4 15 18 injuries & poisonings gray50 15, 4 4, 1 4, 3 3, 0 4, 0 -0.6 0.811 0.459 0.338 0.549 0.0865 1.91 1.99 4.18 0.634 0.198 7.33 0.0207 7110 -1.38 5.3 0.794 0.1 0.251 0.139 0.254 -0.455 82.6 0.996 0.002 0.635 0.00783 101 PRS_PLINK_5e.04 800.4 Fracture of patella Both 2 3 18 injuries & poisonings gray50 3, 2 1, 1 1, 0 1, 1 1, 1 -0.212 1470 1 0 0.809 0.779 1.8 0.00365 63.6 1 0 1 0.936 1.07 -4.65 36800 1 0 0.00954 1.12e-13 54600000 PRS_PLINK_5e.04 801 Fracture of ankle and foot Both 7 36 18 injuries & poisonings gray50 36, 7 8, 1 9, 0 9, 3 9, 3 0.365 0.419 0.384 0.416 1.44 0.668 3.2 0.102 1.65 0.951 0.022 1.11 0.0301 150 3.35 2.39 0.161 0.794 28.6 0.505 155000 0.0256 1.4 0.985 0.006 1.03 0.0125 43.4 PRS_PLINK_5e.04 801.1 Fracture of foot Both 2 14 18 injuries & poisonings gray50 14, 2 4, 1 3, 0 3, 1 4, 0 -1.57 1.48 0.287 0.542 0.208 0.00051 1.47 2.65 5330 1 0 14.1 2.72e-07 21900 -2.24 28.9 0.938 0.028 0.106 0.00343 0.00317 1.04 3420000 1 0 2.82 0.006 1880 PRS_PLINK_5e.04 802 Fracture of pelvis Both 0 5 18 injuries & poisonings gray50 5, 0 2 1 1 1 PRS_PLINK_5e.04 803 Fracture of upper limb Both 6 23 18 injuries & poisonings gray50 23, 6 5, 1 6, 0 5, 2 6, 3 0.664 0.559 0.236 0.628 1.94 0.749 12.5 0.582 2.58 0.822 0.085 1.79 0.0198 447 -2.87 4.94 0.562 0.251 0.057 6.27e-09 570000 -4.91 4.35 0.259 0.586 0.00736 4.49e-08 3.69 PRS_PLINK_5e.04 803.1 Fracture of humerus Both 2 6 18 injuries & poisonings gray50 6, 2 2, 1 1, 1 1, 0 2, 0 -0.0545 1100 1 0 0.947 0.0751 2.23 -0.132 1320 1 0 0.877 0.248 4.92 -0.305 4140 1 0 0.737 0.079 1.98 -5.87 4990 0.999 0 0.00283 8.46e-05 5560000 PRS_PLINK_5e.04 803.2 Fracture of radius and ulna Both 4 14 18 injuries & poisonings gray50 14, 4 4, 1 3, 0 3, 0 4, 3 0.249 0.79 0.753 0.123 1.28 0.342 4.87 2.23 1500 0.999 0.001 9.31 0.0438 16400 -0.129 321 1 0 0.879 8.94 23.2 -3.74 4.66 0.423 0.373 0.0239 1.49e-08 11.2 PRS_PLINK_5e.04 803.21 Colles' fracture Both 0 4 18 injuries & poisonings gray50 4, 0 1 1 1 1 PRS_PLINK_5e.04 803.3 Fracture of clavicle or scapula Both 0 2 18 injuries & poisonings gray50 2, 0 1 1 1 1 PRS_PLINK_5e.04 804 Fracture of hand or wrist Both 8 26 18 injuries & poisonings gray50 26, 8 6, 3 6, 1 6, 2 7, 2 -0.472 0.544 0.386 0.414 0.624 0.154 1.51 -0.62 2.34 0.791 0.102 0.538 0.000107 36.3 -1.46 1.86 0.433 0.364 0.232 0.19 4.38 -1.78 1.61 0.27 0.569 0.169 0.00015 1.95 PRS_PLINK_5e.04 805 Fracture of vertebral column without mention of spinal cord injury Both 2 8 18 injuries & poisonings gray50 8, 2 2, 0 2, 0 2, 2 2, 0 -0.715 1.9 0.707 0.15 0.489 0.016 5.71 -0.00895 2960 1 0 0.991 0.78 2.24 PRS_PLINK_5e.04 807 Fracture of ribs Both 2 8 18 injuries & poisonings gray50 8, 2 2, 0 2, 0 2, 1 2, 1 0.439 2.5 0.861 0.065 1.55 0.0353 106 -0.405 5930 1 0 0.667 0.000159 463 -0.0469 5810 1 0 0.954 0.183 2.33 PRS_PLINK_5e.04 809 Fracture of unspecified bones Both 6 37 18 injuries & poisonings gray50 37, 6 10, 1 9, 0 9, 1 9, 4 1.06 0.706 0.135 0.871 2.87 0.768 33.6 -0.0345 1.35 0.98 0.009 0.966 0.0276 65.4 -0.0289 1.64 0.986 0.006 0.972 0.000463 166 0.501 1.63 0.759 0.12 1.65 0.01 122 PRS_PLINK_5e.04 816 Cerebral laceration and contusion Both 0 3 18 injuries & poisonings gray50 3, 0 1 1 1 1 PRS_PLINK_5e.04 817 Concussion Both 2 22 18 injuries & poisonings gray50 22, 2 5, 1 5, 1 5, 0 6, 0 0.0773 0.662 0.907 0.042 1.08 0.143 7.17 -0.103 2 0.959 0.018 0.902 0.669 1.11 1.92 3.67 0.6 0.222 6.83 0.0354 3640 1.17 4.8 0.807 0.093 3.23 0.000839 3350000 PRS_PLINK_5e.04 818 Intracranial hemorrhage (injury) Both 0 5 18 injuries & poisonings gray50 5, 0 2 1 1 1 PRS_PLINK_5e.04 818.1 Subdural hemorrhage (injury) Both 0 1 18 injuries & poisonings gray50 1, 0 PRS_PLINK_5e.04 818.2 Subarachnoid hemorrhage (injury) Both 0 4 18 injuries & poisonings gray50 4, 0 1 1 1 1 PRS_PLINK_5e.04 819 Skull and face fracture and other intercranial injury Both 4 37 18 injuries & poisonings gray50 37, 4 10, 3 9, 0 9, 0 9, 1 0.391 0.664 0.557 0.254 1.48 0.226 9.74 -0.0244 1.51 0.987 0.006 0.976 0.021 238 0.32 1.57 0.839 0.076 1.38 0.012 21900 0.261 1.56 0.867 0.062 1.3 0.00567 180 PRS_PLINK_5e.04 830 Dislocation Both 12 42 18 injuries & poisonings gray50 42, 12 10, 2 10, 2 10, 4 11, 4 -0.0368 0.355 0.918 0.037 0.964 0.476 1.84 0.868 1.94 0.654 0.184 2.38 0.00613 90100 0.821 1.23 0.506 0.296 2.27 0.172 102 -0.361 1.14 0.751 0.124 0.697 0.0853 5.74 PRS_PLINK_5e.04 835 Internal derangement of knee Both 5 27 18 injuries & poisonings gray50 27, 5 6, 0 7, 2 6, 2 7, 1 -0.0569 0.444 0.898 0.047 0.945 0.376 2.08 -1.15 2.16 0.594 0.226 0.316 0.000305 52.9 0.911 2.04 0.655 0.184 2.49 0.0702 157 -0.018 2.09 0.993 0.003 0.982 0.00409 43.1 PRS_PLINK_5e.04 836 Traumatic arthropathy Both 2 6 18 injuries & poisonings gray50 6, 2 2, 0 1, 0 1, 0 2, 2 4.31e-05 37.1 1 0 1 0.699 1.18 0.00752 252 1 0 1.01 0.851 1.49 PRS_PLINK_5e.04 840 Sprains and strains Both 19 43 18 injuries & poisonings gray50 43, 19 10, 1 11, 6 10, 8 11, 4 0.244 0.312 0.434 0.363 1.28 0.72 2.29 2.39 1.57 0.127 0.895 10.9 0.756 13600 1.48 1.1 0.179 0.748 4.38 0.724 48.2 0.919 1.13 0.415 0.382 2.51 0.376 36.5 PRS_PLINK_5e.04 840.1 Muscle/tendon sprain Both 2 3 18 injuries & poisonings gray50 3, 2 1, 1 1, 0 1, 1 1, 1 0.0435 4430 1 0 1.04 0.452 3.82 -0.0353 96.6 1 0 0.965 0.761 1.36 0.24 9690 1 0 1.27 0.428 4.11 PRS_PLINK_5e.04 840.2 Rotator cuff (capsule) sprain Both 7 16 18 injuries & poisonings gray50 16, 7 4, 1 4, 2 4, 2 4, 2 -0.297 0.725 0.682 0.166 0.743 0.199 2.49 1.31 2.6 0.615 0.211 3.69 0.039 940 -0.471 2.42 0.846 0.073 0.624 0.0123 18.4 -0.177 2.7 0.948 0.023 0.838 0.0157 103 PRS_PLINK_5e.04 840.3 Joint/ligament sprain Both 6 40 18 injuries & poisonings gray50 40, 6 9, 1 10, 1 10, 2 10, 2 0.194 0.415 0.641 0.193 1.21 0.551 3.13 0.126 1.44 0.93 0.031 1.13 0.0247 53.5 -0.0816 1.39 0.953 0.021 0.922 0.0389 17.2 0.567 1.4 0.686 0.164 1.76 0.0777 420 PRS_PLINK_5e.04 841 Sprains and strains of back and neck Both 1 26 18 injuries & poisonings gray50 26, 1 7, 0 6, 1 6, 0 7, 0 -0.189 0.689 0.784 0.106 0.828 0.0435 3.27 0.139 1.84 0.94 0.027 1.15 0.00273 151 PRS_PLINK_5e.04 842 Other sprains and strains Both 4 23 18 injuries & poisonings gray50 23, 4 5, 0 6, 1 5, 2 6, 1 0.109 0.568 0.848 0.071 1.11 0.352 3.71 1.31 2.98 0.661 0.18 3.69 0.0169 2000 0.81 2.08 0.697 0.157 2.25 0.01 136 -0.0167 2.24 0.994 0.003 0.983 0.00399 35.2 PRS_PLINK_5e.04 850 Hemorrhage or hematoma complicating a procedure Both 2 24 18 injuries & poisonings gray50 24, 2 6, 0 6, 1 6, 1 6, 0 0.354 0.779 0.649 0.188 1.42 0.178 42.2 -1.08 2.42 0.657 0.182 0.341 0.00469 61.6 0.321 2.13 0.881 0.055 1.38 0.015 50.9 PRS_PLINK_5e.04 851 Complications of transplants and reattached limbs Both 2 34 18 injuries & poisonings gray50 34, 2 9, 0 8, 1 8, 1 9, 0 0.17 0.543 0.755 0.122 1.18 0.278 4.11 0.581 1.4 0.678 0.169 1.79 0.119 94.1 0.892 1.67 0.593 0.227 2.44 0.12 2920 PRS_PLINK_5e.04 853 Complication of colostomy or enterostomy Both 0 3 18 injuries & poisonings gray50 3, 0 1 1 1 1 PRS_PLINK_5e.04 854 Complications of cardiac/vascular device, implant, and graft Both 4 25 18 injuries & poisonings gray50 25, 4 7, 2 6, 1 6, 1 6, 0 -0.107 0.642 0.868 0.061 0.899 0.207 3.22 0.36 1.53 0.814 0.09 1.43 0.0843 150 -1.09 1.99 0.582 0.235 0.335 2.69e-07 11.5 1.23 3.46 0.722 0.141 3.42 0.0102 15400000 PRS_PLINK_5e.04 855 Complication of nervous system device, implant, and graft Both 1 2 18 injuries & poisonings gray50 2, 1 1, 1 1, 0 1, 1 1, 0 0.0811 79.8 0.999 0 1.08 0.965 1.19 -0.000836 25.9 1 0 0.999 0.984 1.02 PRS_PLINK_5e.04 856 Vascular complications of surgery and medical procedures Both 0 2 18 injuries & poisonings gray50 2, 0 1 1 1 1 PRS_PLINK_5e.04 857 Mechanical complication of unspecified genitourinary device, implant, and graft Both 4 20 18 injuries & poisonings gray50 20, 4 5, 0 5, 2 5, 2 5, 0 -0.693 0.917 0.45 0.347 0.5 0.0536 2.46 5.48 5.59 0.326 0.486 241 0.0898 7160000 1.72 8.16 0.833 0.079 5.58 1.79e-06 34300000 PRS_PLINK_5e.04 858 Complication of internal orthopedic device Both 2 23 18 injuries & poisonings gray50 23, 2 6, 0 6, 0 5, 1 6, 1 0.336 0.663 0.613 0.213 1.4 0.257 273 1.51 5.98 0.801 0.096 4.52 1.81e-05 2940000 -0.621 3.77 0.869 0.061 0.537 7.06e-05 5260 PRS_PLINK_5e.04 859 Complication due to other implant and internal device Both 1 21 18 injuries & poisonings gray50 21, 1 6, 1 5, 0 5, 0 5, 0 -0.0157 0.892 0.986 0.006 0.984 0.119 14.8 1.14 2.74 0.678 0.169 3.11 0.0374 2120 0.221 2.5 0.929 0.032 1.25 1.13 1.33 1.51 5.33 0.777 0.11 4.53 0.000384 3050000 PRS_PLINK_5e.04 860 Bone marrow or stem cell transplant Both 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_5e.04 870 Open wounds of head; neck; and trunk Both 5 48 18 injuries & poisonings gray50 48, 5 12, 1 12, 0 12, 1 12, 3 0.631 0.452 0.162 0.79 1.88 0.781 5.41 -0.0375 1.38 0.978 0.01 0.963 0.0134 39.1 0.516 1.39 0.711 0.148 1.68 0.102 582 0.946 1.22 0.437 0.359 2.58 0.268 40.6 PRS_PLINK_5e.04 870.1 Open wound or laceration of eye or eyelid Both 0 2 18 injuries & poisonings gray50 2, 0 1 1 1 1 PRS_PLINK_5e.04 870.2 Open wound of ear Both 0 3 18 injuries & poisonings gray50 3, 0 1 1 1 1 PRS_PLINK_5e.04 870.3 Other open wound of head and face Both 1 13 18 injuries & poisonings gray50 13, 1 4, 0 3, 0 3, 0 3, 1 0.67 1.07 0.531 0.275 1.95 0.235 21.1 0.0306 118 1 0 1.03 0.932 1.6 PRS_PLINK_5e.04 870.4 Open wound of nose and sinus Both 1 2 18 injuries & poisonings gray50 2, 1 1, 0 1, 1 1, 0 1, 1 -0.0258 45.2 1 0 0.975 0.925 1.02 -0.00375 22.6 1 0 0.996 0.975 1.02 PRS_PLINK_5e.04 870.5 Open wound of lip and mouth Both 0 7 18 injuries & poisonings gray50 7, 0 2 2 1 2 PRS_PLINK_5e.04 870.6 Open wound of neck Both 0 1 18 injuries & poisonings gray50 1, 0 PRS_PLINK_5e.04 870.8 Open wound of genital organs Both 1 1 18 injuries & poisonings gray50 1, 1 0.00669 1290 1 0 1.01 0.869 1.17 PRS_PLINK_5e.04 871 Open wounds of extremities Both 7 49 18 injuries & poisonings gray50 49, 7 13, 0 12, 3 12, 2 12, 2 0.394 0.535 0.462 0.335 1.48 0.4 4.94 1.5 1.61 0.352 0.453 4.48 0.0823 15100 0.471 1.26 0.708 0.15 1.6 0.0244 123 1.06 1.27 0.403 0.394 2.88 0.151 1750 PRS_PLINK_5e.04 871.1 Open wound of hand except finger(s) Both 1 13 18 injuries & poisonings gray50 13, 1 4, 0 3, 0 3, 0 3, 1 -0.212 1.12 0.85 0.071 0.809 0.0464 30.9 -0.096 249 1 0 0.909 0.439 0.476 PRS_PLINK_5e.04 871.2 Open wound of finger(s) Both 4 25 18 injuries & poisonings gray50 25, 4 7, 0 6, 3 6, 0 6, 1 -0.0376 0.681 0.956 0.02 0.963 0.17 3.57 0.439 2.1 0.834 0.079 1.55 0.0107 598 -0.237 2.51 0.925 0.034 0.789 0.00022 637 PRS_PLINK_5e.04 871.3 Open wound of foot except toe(s) alone Both 1 12 18 injuries & poisonings gray50 12, 1 3, 0 3, 0 3, 1 3, 0 0.17 2.47 0.945 0.025 1.19 0.000434 428 0.194 20000 1 0 1.21 0.503 1.56 PRS_PLINK_5e.04 871.4 Open wound of toe(s) Both 2 9 18 injuries & poisonings gray50 9, 2 3, 0 2, 0 2, 1 2, 1 0.0519 3.05 0.986 0.006 1.05 0.0103 130 -0.0282 1030 1 0 0.972 0.764 1.16 1.44 2640 1 0 4.23 0.0153 1160 PRS_PLINK_5e.04 872 Traumatic amputation Both 1 15 18 injuries & poisonings gray50 15, 1 4, 0 4, 1 3, 0 4, 0 0.575 1.42 0.686 0.164 1.78 0.0524 29.8 0.00803 46.3 1 0 1.01 0.941 1.41 PRS_PLINK_5e.04 874 Complication of amputation stump Both 0 3 18 injuries & poisonings gray50 3, 0 1 1 1 1 PRS_PLINK_5e.04 875 Non-healing surgical wound Both 0 4 18 injuries & poisonings gray50 4, 0 1 1 1 1 PRS_PLINK_5e.04 876 Posttraumatic wound infection not elsewhere classified Both 0 9 18 injuries & poisonings gray50 9, 0 3 2 2 2 PRS_PLINK_5e.04 907 Injuries to the nervous system Both 2 16 18 injuries & poisonings gray50 16, 2 4, 1 4, 0 4, 1 4, 0 -0.47 0.862 0.586 0.232 0.625 0.0136 2.78 1.12 24.4 0.963 0.016 3.07 2.91 3.25 1.18 2.91 0.686 0.163 3.24 0.0393 229 -0.481 122 0.997 0.001 0.618 0.000653 499 PRS_PLINK_5e.04 910 Superficial injury, infected Both 0 3 18 injuries & poisonings gray50 3, 0 1 1 1 1 PRS_PLINK_5e.04 911 Blister Both 5 8 18 injuries & poisonings gray50 8, 5 2, 0 2, 0 2, 0 2, 5 0.103 1.29 0.936 0.029 1.11 0.0555 8.28 -0.0364 25.9 0.999 0 0.964 0.768 1.41 PRS_PLINK_5e.04 912 Insect bite Both 0 9 18 injuries & poisonings gray50 9, 0 3 2 2 2 PRS_PLINK_5e.04 913 Toxic effect of venom Both 2 6 18 injuries & poisonings gray50 6, 2 2, 0 1, 2 1, 0 2, 0 -0.0214 107 1 0 0.979 0.0811 9.26 0.114 893 1 0 1.12 0.655 1.13 PRS_PLINK_5e.04 916 Contusion Both 8 48 18 injuries & poisonings gray50 48, 8 12, 1 12, 1 12, 3 12, 3 0.295 0.43 0.493 0.307 1.34 0.556 3.2 0.822 1.6 0.607 0.217 2.27 0.0116 240 2.21 1.7 0.194 0.713 9.13 0.383 3150 0.954 1.38 0.491 0.309 2.6 0.245 153000 PRS_PLINK_5e.04 930 Allergic reaction to food Both 0 10 18 injuries & poisonings gray50 10, 0 3 2 2 3 PRS_PLINK_5e.04 931 Contact dermatitis and other eczema due to plants [except food] Both 1 11 13 dermatologic firebrick 11, 1 3, 0 3, 0 2, 0 3, 1 0.375 1.14 0.741 0.13 1.46 0.131 8.12 -0.0205 262 1 0 0.98 0.812 1.38 PRS_PLINK_5e.04 938 Dermatitis due to solar radiation Both 8 32 13 dermatologic firebrick 32, 8 8, 1 8, 3 8, 0 8, 4 0.0809 0.476 0.865 0.063 1.08 0.445 2.61 0.535 1.19 0.652 0.186 1.71 0.153 14.4 -0.515 1.94 0.79 0.102 0.597 0.00977 82.2 1.09 1.4 0.437 0.36 2.98 0.275 91.7 PRS_PLINK_5e.04 938.1 Acute dermatitis due to solar radiation Both 0 4 13 dermatologic firebrick 4, 0 1 1 1 1 PRS_PLINK_5e.04 938.2 Chronic dermatitis due to solar radiation Both 8 31 13 dermatologic firebrick 31, 8 8, 1 8, 3 7, 0 8, 4 0.0804 0.475 0.866 0.063 1.08 0.447 2.61 0.413 1.25 0.741 0.13 1.51 0.0714 14.6 -0.307 2.01 0.878 0.056 0.735 0.0201 70.1 1.09 1.4 0.437 0.36 2.98 0.275 91.7 PRS_PLINK_5e.04 939 Atopic/contact dermatitis due to other or unspecified Both 12 40 13 dermatologic firebrick 40, 12 9, 1 10, 4 10, 4 10, 3 0.00447 0.42 0.992 0.004 1 0.469 2.15 0.754 1.13 0.505 0.297 2.12 0.3 19.8 1.27 1.5 0.396 0.403 3.57 0.277 929 1.07 1.33 0.422 0.374 2.91 0.321 42.1 PRS_PLINK_5e.04 939.1 Contact and allergic dermatitis of eyelid Both 0 1 13 dermatologic firebrick 1, 0 PRS_PLINK_5e.04 941 Adverse reaction to serum or vaccine Both 0 5 18 injuries & poisonings gray50 5, 0 2 1 1 1 PRS_PLINK_5e.04 942 Infusion and transfusion reaction Both 0 4 18 injuries & poisonings gray50 4, 0 1 1 1 1 PRS_PLINK_5e.04 946 Anaphylactic shock NOS Both 3 5 18 injuries & poisonings gray50 5, 3 2, 0 1, 1 1, 0 1, 2 -0.306 684 1 0 0.737 0.388 2.83 -0.534 5790 1 0 0.586 0.0495 3.65 0.942 24200 1 0 2.57 0.13 11.4 PRS_PLINK_5e.04 947 Urticaria Both 5 15 13 dermatologic firebrick 15, 5 4, 0 4, 1 3, 0 4, 4 0.858 1.1 0.437 0.36 2.36 0.377 43 -0.0241 2.43 0.992 0.003 0.976 0.0306 60.1 2.02 3.64 0.579 0.237 7.5 0.000626 86.1 PRS_PLINK_5e.04 949 Allergies, other Both 13 40 18 injuries & poisonings gray50 40, 13 9, 2 10, 5 10, 1 10, 5 -0.0615 0.447 0.891 0.05 0.94 0.363 2.15 0.607 0.977 0.534 0.272 1.83 0.341 12 0.238 1.26 0.85 0.07 1.27 0.137 26.4 -1.07 1.64 0.514 0.289 0.343 2.54e-06 6.2 PRS_PLINK_5e.04 952 Spinal cord injury without evidence of spinal bone injury Both 1 8 18 injuries & poisonings gray50 8, 1 2, 0 2, 0 2, 0 2, 1 -0.204 94.7 0.998 0.001 0.815 0.239 2.21 0.0494 2530 1 0 1.05 0.62 1.09 PRS_PLINK_5e.04 957 Injury to other and unspecified nerves Both 1 1 18 injuries & poisonings gray50 1, 1 0.000445 582 1 0 1 0.994 1.01 PRS_PLINK_5e.04 958 Certain early complications of trauma or procedure Both 0 10 18 injuries & poisonings gray50 10, 0 3 2 2 3 PRS_PLINK_5e.04 958.1 Postoperative shock Both 0 2 18 injuries & poisonings gray50 2, 0 1 1 1 1 PRS_PLINK_5e.04 960 Poisoning by antibiotics Both 5 26 18 injuries & poisonings gray50 26, 5 7, 0 6, 2 6, 1 7, 2 0.928 0.591 0.116 0.935 2.53 0.946 8.54 0.233 2.01 0.908 0.042 1.26 0.000147 8560 1.25 2.15 0.561 0.251 3.48 0.103 314 2.31 3.04 0.448 0.349 10 0.0514 2000 PRS_PLINK_5e.04 960.1 Adverse effects of antibacterials (not penicillins) Both 0 3 18 injuries & poisonings gray50 3, 0 1 1 1 1 PRS_PLINK_5e.04 960.2 Allergy/adverse effect of penicillin Both 3 19 18 injuries & poisonings gray50 19, 3 5, 1 5, 0 4, 1 5, 1 0.366 0.965 0.705 0.152 1.44 0.118 70.8 -0.485 6.6 0.941 0.026 0.616 7e-05 4600 1.04 6.47 0.872 0.06 2.84 0.000154 1.54e+08 0.563 6.19 0.928 0.033 1.76 0.000196 29800 PRS_PLINK_5e.04 961 Poisoning by other anti-infectives Both 0 9 18 injuries & poisonings gray50 9, 0 3 2 2 2 PRS_PLINK_5e.04 961.1 Poisoning/allergy of sulfonamides Both 2 6 18 injuries & poisonings gray50 6, 2 2, 1 1, 0 1, 0 2, 1 0.304 5730000 1 0 1.35 0.0265 17.3 0.0033 29.4 1 0 1 0.98 1.05 -0.193 1.6e+07 1 0 0.825 5.89e-08 41600 0.617 2680 1 0 1.85 2e-08 3.03e+10 PRS_PLINK_5e.04 962 Poisoning by hormones and synthetic substitutes Both 3 16 18 injuries & poisonings gray50 16, 3 4, 0 4, 2 4, 0 4, 1 0.522 0.837 0.533 0.274 1.69 0.123 7.47 -0.174 2720 1 0 0.84 0.724 1.52 -2.03 81.4 0.98 0.009 0.131 5.13e-07 0.159 PRS_PLINK_5e.04 962.1 Adrenal cortical steroids causing adverse effects in therapeutic use Both 1 8 18 injuries & poisonings gray50 8, 1 2, 1 2, 0 2, 0 2, 0 -0.0223 16.7 0.999 0 0.978 0.116 22.1 -0.0838 393 1 0 0.92 0.525 1.46 0.0944 7620 1 0 1.1 0.154 1.17 -0.00286 875 1 0 0.997 0.761 1.33 PRS_PLINK_5e.04 962.2 Insulins and antidiabetic agents causing adverse effects in therapeutic use Both 1 1 18 injuries & poisonings gray50 1, 1 -0.000217 821 1 0 1 0.948 1.06 PRS_PLINK_5e.04 962.3 Hormones and synthetic substitutes causing adverse effects in therapeutic use Both 2 9 18 injuries & poisonings gray50 9, 2 3, 1 2, 0 2, 0 2, 1 0.722 1.47 0.624 0.205 2.06 0.075 43.2 0.18 894 1 0 1.2 0.286 1.56 0.0216 3430 1 0 1.02 0.48 2.2 0.118 3860 1 0 1.12 0.526 1.34 PRS_PLINK_5e.04 963 Poisoning by primarily systemic agents Both 0 25 18 injuries & poisonings gray50 25, 0 7 6 6 6 PRS_PLINK_5e.04 963.1 Antineoplastic and immunosuppressive drugs causing adverse effects Both 0 23 18 injuries & poisonings gray50 23, 0 6 6 5 6 PRS_PLINK_5e.04 964 Poisoning by agents primarily affecting blood constituents Both 0 13 18 injuries & poisonings gray50 13, 0 4 3 3 3 PRS_PLINK_5e.04 964.1 Anticoagulants causing adverse effects Both 0 12 18 injuries & poisonings gray50 12, 0 3 3 3 3 PRS_PLINK_5e.04 965 Poisoning by analgesics, antipyretics, and antirheumatics Both 1 5 18 injuries & poisonings gray50 5, 1 2, 1 1, 0 1, 0 1, 0 0.0786 2690 1 0 1.08 0.558 1.36 1.25e-05 16800 1 0 1 0.205 2.77 -0.0141 6720 1 0 0.986 0.11 1.67 -0.0688 14700 1 0 0.933 0.16 3.01 PRS_PLINK_5e.04 965.1 Opiates and related narcotics causing adverse effects in therapeutic use Both 1 16 18 injuries & poisonings gray50 16, 1 4, 1 4, 0 4, 0 4, 0 -1.09 1.71 0.526 0.279 0.337 0.00527 7.23 2.56 328 0.994 0.003 13 2.98e-06 1250000 -0.695 385 0.999 0.001 0.499 0.00126 131 0.726 240 0.998 0.001 2.07 0.0785 1950 PRS_PLINK_5e.04 965.3 Salicylates causing adverse effects in therapeutic use Both 0 1 18 injuries & poisonings gray50 1, 0 PRS_PLINK_5e.04 966 Poisoning by anticonvulsants and anti-Parkinsonism drugs Both 0 2 18 injuries & poisonings gray50 2, 0 1 1 1 1 PRS_PLINK_5e.04 967 Adverse effects of sedatives or other central nervous system depressants and anesthetics Both 0 12 18 injuries & poisonings gray50 12, 0 3 3 3 3 PRS_PLINK_5e.04 969 Poisoning by psychotropic agents Both 0 1 18 injuries & poisonings gray50 1, 0 PRS_PLINK_5e.04 972 Poisoning by agents primarily affecting the cardiovascular system Both 0 4 18 injuries & poisonings gray50 4, 0 1 1 1 1 PRS_PLINK_5e.04 972.6 Antihypertensive agents causing adverse effects Both 0 1 18 injuries & poisonings gray50 1, 0 PRS_PLINK_5e.04 974 Poisoning by water, mineral, and uric acid metabolism drugs Both 0 1 18 injuries & poisonings gray50 1, 0 PRS_PLINK_5e.04 975 Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system Both 0 1 18 injuries & poisonings gray50 1, 0 PRS_PLINK_5e.04 976 Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs Both 1 0 18 injuries & poisonings gray50 0, 1 PRS_PLINK_5e.04 977 Personal history of allergy to medicinal agents Both 0 21 18 injuries & poisonings gray50 21, 0 6 5 5 5 PRS_PLINK_5e.04 979 Adverse drug events and drug allergies Both 5 38 18 injuries & poisonings gray50 38, 5 10, 0 9, 4 9, 1 10, 0 -0.0106 0.672 0.987 0.006 0.989 0.211 3.79 0.812 1.59 0.61 0.215 2.25 0.112 306 1.05 1.62 0.516 0.287 2.87 0.0101 121 PRS_PLINK_5e.04 980 Encounter for long-term (current) use of antibiotics Both 3 13 1 infectious diseases blue 13, 3 3, 2 3, 0 3, 1 3, 0 0.172 0.79 0.827 0.082 1.19 0.139 7.95 -0.367 1790000 1 0 0.693 0.204 1.16 -0.528 30.7 0.986 0.006 0.59 0.547 70.4 0.177 5920000 1 0 1.19 0.0184 82.4 PRS_PLINK_5e.04 985 Toxic effect of other metals Both 1 0 18 injuries & poisonings gray50 0, 1 PRS_PLINK_5e.04 989 Toxic effect of other substances, chiefly nonmedicinal as to source Both 1 2 18 injuries & poisonings gray50 2, 1 1, 0 1, 1 1, 0 1, 1 -0.00237 71.3 1 0 0.998 0.886 1.1 -0.0255 66.1 1 0 0.975 0.912 1.05 PRS_PLINK_5e.04 990 Effects radiation NOS Both 0 21 18 injuries & poisonings gray50 21, 0 6 5 5 5 PRS_PLINK_5e.04 994 Sepsis and SIRS Both 1 27 18 injuries & poisonings gray50 27, 1 7, 0 7, 0 6, 1 7, 0 -0.135 0.875 0.878 0.057 0.874 0.00171 6.47 1.2 1.86 0.519 0.285 3.31 0.183 1880 PRS_PLINK_5e.04 994.1 Systemic inflammatory response syndrome (SIRS) Both 0 2 18 injuries & poisonings gray50 2, 0 1 1 1 1 PRS_PLINK_5e.04 994.2 Sepsis Both 1 27 18 injuries & poisonings gray50 27, 1 7, 0 7, 0 6, 1 7, 0 -0.118 0.905 0.897 0.047 0.889 0.00196 7.06 1.06 1.87 0.57 0.244 2.89 0.177 4980 PRS_PLINK_5e.04 994.21 Septic shock Both 0 6 18 injuries & poisonings gray50 6, 0 2 1 1 2 PRS_PLINK_5e.04