phewas_code phewas_string sex MatchedCases MatchedControls groupnum group color N N_Q1 N_Q2 N_Q3 N_Q4 PRS_BETA PRS_SEBETA PRS_P PRS_LOG10P PRS_OR PRS_CI1 PRS_CI2 Q1Q2_BETA Q1Q2_SEBETA Q1Q2_P Q1Q2_LOG10P Q1Q2_OR Q1Q2_CI1 Q1Q2_CI2 Q1Q3_BETA Q1Q3_SEBETA Q1Q3_P Q1Q3_LOG10P Q1Q3_OR Q1Q3_CI1 Q1Q3_CI2 Q1Q4_BETA Q1Q4_SEBETA Q1Q4_P Q1Q4_LOG10P Q1Q4_OR Q1Q4_CI1 Q1Q4_CI2 predictor 008 Intestinal infection Both 5538 63928 1 infectious diseases blue 63928, 5538 15965, 1372 16091, 1348 16109, 1439 15744, 1378 0.0217 0.0139 0.119 0.9238 1.02 0.994 1.05 -0.0254 0.0399 0.526 0.2794 0.975 0.902 1.05 0.0411 0.0393 0.296 0.5288 1.04 0.965 1.13 0.021 0.0398 0.597 0.2237 1.02 0.945 1.1 PRS_PLINK_1.99526231496888e.06 008.5 Bacterial enteritis Both 1663 19453 1 infectious diseases blue 19453, 1663 4859, 398 4885, 396 4930, 451 4774, 417 0.0419 0.0251 0.0954 1.02 1.04 0.993 1.1 -0.00972 0.0737 0.895 0.04813 0.99 0.857 1.14 0.117 0.0716 0.103 0.9858 1.12 0.977 1.29 0.0715 0.073 0.327 0.4859 1.07 0.931 1.24 PRS_PLINK_1.99526231496888e.06 008.52 Intestinal infection due to C. difficile Both 316 4512 1 infectious diseases blue 4512, 316 1140, 78 1125, 67 1119, 88 1128, 83 0.0809 0.0568 0.154 0.8114 1.08 0.97 1.21 -0.117 0.17 0.49 0.3096 0.889 0.637 1.24 0.141 0.16 0.379 0.4214 1.15 0.841 1.57 0.0868 0.162 0.592 0.2279 1.09 0.794 1.5 PRS_PLINK_1.99526231496888e.06 008.6 Viral Enteritis Both 514 6251 1 infectious diseases blue 6251, 514 1587, 124 1546, 125 1554, 125 1561, 140 0.0276 0.0454 0.542 0.2657 1.03 0.941 1.12 0.0357 0.131 0.785 0.1049 1.04 0.802 1.34 0.0265 0.131 0.84 0.07592 1.03 0.794 1.33 0.144 0.128 0.26 0.5853 1.16 0.899 1.48 PRS_PLINK_1.99526231496888e.06 008.7 Intestinal infection due to protozoa Both 32 412 1 infectious diseases blue 412, 32 103, 7 104, 11 102, 6 103, 8 0.038 0.167 0.82 0.08632 1.04 0.749 1.44 0.459 0.473 0.332 0.4787 1.58 0.626 4 0.0142 0.525 0.978 0.00947 1.01 0.363 2.84 0.221 0.511 0.666 0.1766 1.25 0.458 3.39 PRS_PLINK_1.99526231496888e.06 010 Tuberculosis Both 100 1154 1 infectious diseases blue 1154, 100 288, 23 288, 28 290, 21 287, 28 0.0125 0.102 0.903 0.04446 1.01 0.829 1.24 0.191 0.287 0.507 0.2952 1.21 0.689 2.13 -0.111 0.304 0.714 0.1462 0.895 0.493 1.62 0.187 0.287 0.515 0.2884 1.21 0.686 2.12 PRS_PLINK_1.99526231496888e.06 038 Septicemia Both 2126 29197 1 infectious diseases blue 29197, 2126 7293, 521 7337, 514 7260, 529 7296, 562 0.0349 0.0222 0.116 0.937 1.04 0.991 1.08 -0.0186 0.0643 0.773 0.112 0.982 0.865 1.11 0.0228 0.0638 0.721 0.142 1.02 0.903 1.16 0.0801 0.063 0.204 0.6904 1.08 0.957 1.23 PRS_PLINK_1.99526231496888e.06 038.1 Gram negative septicemia Both 415 5900 1 infectious diseases blue 5900, 415 1479, 102 1475, 100 1473, 103 1471, 110 0.0434 0.05 0.385 0.4147 1.04 0.947 1.15 -0.0192 0.144 0.894 0.04858 0.981 0.739 1.3 0.0205 0.143 0.886 0.05238 1.02 0.771 1.35 0.093 0.142 0.511 0.2915 1.1 0.832 1.45 PRS_PLINK_1.99526231496888e.06 038.2 Gram positive septicemia Both 227 3457 1 infectious diseases blue 3457, 227 873, 48 856, 53 875, 68 852, 58 0.0931 0.0662 0.16 0.7969 1.1 0.964 1.25 0.113 0.202 0.576 0.2394 1.12 0.754 1.66 0.351 0.192 0.0676 1.17 1.42 0.975 2.07 0.204 0.198 0.303 0.5182 1.23 0.831 1.81 PRS_PLINK_1.99526231496888e.06 041 Bacterial infection NOS Both 6955 85937 1 infectious diseases blue 85937, 6955 21455, 1623 21527, 1706 21521, 1874 21404, 1750 0.0406 0.0123 0.000975 3.011 1.04 1.02 1.07 0.0473 0.036 0.189 0.7244 1.05 0.977 1.13 0.143 0.0353 4.84e-05 4.316 1.15 1.08 1.24 0.0834 0.0358 0.02 1.698 1.09 1.01 1.17 PRS_PLINK_1.99526231496888e.06 041.1 Staphylococcus infections Both 1679 22196 1 infectious diseases blue 22196, 1679 5547, 358 5581, 402 5517, 452 5548, 467 0.107 0.0248 1.43e-05 4.843 1.11 1.06 1.17 0.109 0.075 0.145 0.8397 1.12 0.963 1.29 0.241 0.0731 0.000981 3.008 1.27 1.1 1.47 0.277 0.0728 0.000144 3.84 1.32 1.14 1.52 PRS_PLINK_1.99526231496888e.06 041.2 Streptococcus infection Both 976 11987 1 infectious diseases blue 11987, 976 2996, 217 3016, 236 3021, 275 2953, 248 0.044 0.0328 0.18 0.7445 1.04 0.98 1.11 0.0773 0.0972 0.426 0.3702 1.08 0.893 1.31 0.228 0.0942 0.0154 1.812 1.26 1.04 1.51 0.159 0.0964 0.0994 1.003 1.17 0.97 1.42 PRS_PLINK_1.99526231496888e.06 041.4 E. coli Both 1520 19569 1 infectious diseases blue 19569, 1520 4925, 329 4864, 392 4935, 424 4835, 375 0.057 0.026 0.0284 1.547 1.06 1.01 1.11 0.186 0.0773 0.016 1.797 1.2 1.04 1.4 0.254 0.0761 0.000836 3.078 1.29 1.11 1.5 0.153 0.0781 0.0502 1.299 1.17 1 1.36 PRS_PLINK_1.99526231496888e.06 053 Herpes zoster Both 225 2821 1 infectious diseases blue 2821, 225 707, 52 707, 59 705, 57 702, 57 0.0123 0.0684 0.857 0.06697 1.01 0.885 1.16 0.12 0.195 0.539 0.2682 1.13 0.769 1.65 0.0924 0.197 0.639 0.1946 1.1 0.746 1.61 0.0833 0.198 0.674 0.1717 1.09 0.738 1.6 PRS_PLINK_1.99526231496888e.06 053.1 Herpes zoster with nervous system complications Both 57 644 1 infectious diseases blue 644, 57 161, 20 163, 14 159, 11 161, 12 -0.35 0.15 0.0199 1.701 0.705 0.525 0.946 -0.389 0.357 0.275 0.5599 0.678 0.337 1.36 -0.667 0.381 0.0805 1.094 0.513 0.243 1.08 -0.564 0.373 0.131 0.8818 0.569 0.274 1.18 PRS_PLINK_1.99526231496888e.06 054 Herpes simplex Both 141 1606 1 infectious diseases blue 1606, 141 404, 38 400, 31 402, 31 399, 41 -0.0145 0.0864 0.867 0.06195 0.986 0.832 1.17 -0.197 0.247 0.426 0.3708 0.821 0.506 1.33 -0.179 0.247 0.468 0.3294 0.836 0.515 1.36 0.0862 0.233 0.711 0.1479 1.09 0.69 1.72 PRS_PLINK_1.99526231496888e.06 070 Viral hepatitis Both 323 4477 1 infectious diseases blue 4477, 323 1119, 74 1126, 80 1117, 82 1113, 87 0.0436 0.0565 0.44 0.3563 1.04 0.935 1.17 0.0705 0.165 0.669 0.1743 1.07 0.776 1.48 0.109 0.165 0.51 0.2924 1.11 0.807 1.54 0.188 0.163 0.247 0.6066 1.21 0.877 1.66 PRS_PLINK_1.99526231496888e.06 070.1 Viral hepatitis A Both 48 549 1 infectious diseases blue 549, 48 138, 14 137, 8 137, 11 137, 15 0.0956 0.143 0.504 0.2975 1.1 0.831 1.46 -0.484 0.434 0.264 0.5777 0.616 0.263 1.44 -0.232 0.403 0.565 0.248 0.793 0.36 1.75 0.0795 0.377 0.833 0.07942 1.08 0.517 2.27 PRS_PLINK_1.99526231496888e.06 070.2 Viral hepatitis B Both 73 968 1 infectious diseases blue 968, 73 242, 13 243, 19 241, 21 242, 20 0.101 0.111 0.366 0.4362 1.11 0.889 1.38 0.379 0.355 0.287 0.5427 1.46 0.728 2.93 0.465 0.353 0.188 0.7263 1.59 0.797 3.18 0.457 0.357 0.201 0.6963 1.58 0.784 3.18 PRS_PLINK_1.99526231496888e.06 070.3 Viral hepatitis C Both 132 2012 1 infectious diseases blue 2012, 132 503, 30 507, 29 499, 33 503, 40 0.0861 0.0884 0.33 0.4809 1.09 0.916 1.3 -0.085 0.262 0.746 0.1273 0.919 0.549 1.54 0.134 0.255 0.598 0.2232 1.14 0.694 1.88 0.266 0.245 0.278 0.5564 1.31 0.807 2.11 PRS_PLINK_1.99526231496888e.06 070.4 Chronic hepatitis Both 140 2057 1 infectious diseases blue 2057, 140 515, 45 516, 29 515, 28 511, 38 -0.111 0.0901 0.217 0.6632 0.895 0.75 1.07 -0.417 0.242 0.0851 1.07 0.659 0.41 1.06 -0.428 0.244 0.0798 1.098 0.652 0.404 1.05 -0.0965 0.228 0.671 0.173 0.908 0.581 1.42 PRS_PLINK_1.99526231496888e.06 070.9 Hepatitis NOS Both 224 3107 1 infectious diseases blue 3107, 224 788, 59 770, 45 790, 66 757, 54 0.0239 0.0671 0.722 0.1414 1.02 0.898 1.17 -0.236 0.202 0.241 0.6181 0.789 0.532 1.17 0.0839 0.185 0.65 0.1872 1.09 0.757 1.56 -0.0654 0.193 0.735 0.1336 0.937 0.641 1.37 PRS_PLINK_1.99526231496888e.06 071 Human immunodeficiency virus [HIV] disease Both 73 1099 1 infectious diseases blue 1099, 73 280, 19 271, 17 274, 19 274, 18 0.0622 0.113 0.581 0.2355 1.06 0.853 1.33 -0.129 0.334 0.7 0.155 0.879 0.457 1.69 0.0414 0.328 0.9 0.04597 1.04 0.548 1.98 -0.035 0.328 0.915 0.0386 0.966 0.508 1.84 PRS_PLINK_1.99526231496888e.06 071.1 HIV infection, symptomatic Both 59 878 1 infectious diseases blue 878, 59 228, 17 211, 13 220, 14 219, 15 0.0776 0.124 0.53 0.2755 1.08 0.848 1.38 -0.228 0.367 0.534 0.2726 0.796 0.387 1.63 -0.145 0.359 0.688 0.1627 0.865 0.428 1.75 -0.0597 0.35 0.865 0.06314 0.942 0.474 1.87 PRS_PLINK_1.99526231496888e.06 078 Viral warts & HPV Both 706 7578 1 infectious diseases blue 7578, 706 1902, 174 1884, 179 1897, 175 1892, 178 0.00776 0.0393 0.843 0.07404 1.01 0.933 1.09 0.0427 0.111 0.7 0.1547 1.04 0.84 1.3 0.014 0.112 0.9 0.04574 1.01 0.815 1.26 0.0296 0.111 0.79 0.1024 1.03 0.828 1.28 PRS_PLINK_1.99526231496888e.06 079 Viral infection Both 1923 21181 1 infectious diseases blue 21181, 1923 5294, 486 5354, 474 5231, 508 5293, 455 -0.0125 0.0241 0.605 0.218 0.988 0.942 1.04 -0.0331 0.0673 0.623 0.2054 0.967 0.848 1.1 0.0606 0.0663 0.361 0.4422 1.06 0.933 1.21 -0.0608 0.0681 0.372 0.4299 0.941 0.823 1.08 PRS_PLINK_1.99526231496888e.06 079.1 Varicella infection Both 46 518 1 infectious diseases blue 518, 46 132, 16 129, 10 127, 9 130, 11 -0.0824 0.151 0.586 0.2325 0.921 0.685 1.24 -0.418 0.406 0.304 0.5176 0.659 0.297 1.46 -0.445 0.419 0.288 0.541 0.641 0.282 1.46 -0.43 0.406 0.29 0.5383 0.651 0.294 1.44 PRS_PLINK_1.99526231496888e.06 080 Postoperative infection Both 2675 32311 1 infectious diseases blue 32311, 2675 8126, 664 8098, 637 8100, 695 7979, 679 0.0329 0.02 0.1 1 1.03 0.994 1.07 -0.0366 0.0576 0.525 0.2801 0.964 0.861 1.08 0.0471 0.0565 0.404 0.3935 1.05 0.938 1.17 0.0488 0.0569 0.391 0.408 1.05 0.939 1.17 PRS_PLINK_1.99526231496888e.06 081 Infection/inflammation of internal prosthetic device; implant; and graft Both 1363 17494 1 infectious diseases blue 17494, 1363 4437, 327 4323, 315 4358, 369 4373, 352 0.0622 0.0278 0.0251 1.6 1.06 1.01 1.12 -0.00986 0.0816 0.904 0.04391 0.99 0.844 1.16 0.144 0.0788 0.0679 1.168 1.15 0.989 1.35 0.09 0.0796 0.258 0.5881 1.09 0.936 1.28 PRS_PLINK_1.99526231496888e.06 090 Sexually transmitted infections (not HIV or hepatitis) Both 45 535 1 infectious diseases blue 535, 45 133, 9 134, 12 133, 15 134, 9 -0.0533 0.158 0.736 0.1331 0.948 0.696 1.29 0.331 0.438 0.45 0.3463 1.39 0.59 3.28 0.517 0.417 0.215 0.6675 1.68 0.741 3.8 0.0789 0.461 0.864 0.06339 1.08 0.438 2.67 PRS_PLINK_1.99526231496888e.06 110 Dermatophytosis / Dermatomycosis Both 161 1992 1 infectious diseases blue 1992, 161 498, 35 499, 37 502, 37 493, 52 0.109 0.0796 0.172 0.7633 1.11 0.954 1.3 0.0466 0.239 0.846 0.07274 1.05 0.655 1.68 0.0464 0.24 0.847 0.07223 1.05 0.654 1.68 0.397 0.224 0.0766 1.116 1.49 0.958 2.31 PRS_PLINK_1.99526231496888e.06 110.1 Dermatophytosis Both 157 1957 1 infectious diseases blue 1957, 157 493, 33 487, 36 492, 36 485, 52 0.125 0.0804 0.121 0.9169 1.13 0.968 1.33 0.0985 0.244 0.687 0.1632 1.1 0.684 1.78 0.0808 0.245 0.742 0.1297 1.08 0.67 1.75 0.455 0.229 0.0465 1.333 1.58 1.01 2.47 PRS_PLINK_1.99526231496888e.06 110.11 Dermatophytosis of nail Both 47 532 1 infectious diseases blue 532, 47 138, 12 128, 11 133, 11 133, 13 -0.0194 0.151 0.898 0.0468 0.981 0.729 1.32 0.0096 0.414 0.981 0.008114 1.01 0.449 2.27 0.0134 0.417 0.974 0.01125 1.01 0.447 2.3 0.171 0.404 0.671 0.1731 1.19 0.538 2.62 PRS_PLINK_1.99526231496888e.06 110.12 Althete's foot Both 77 994 1 infectious diseases blue 994, 77 250, 15 247, 20 248, 16 249, 26 0.136 0.113 0.227 0.6444 1.15 0.919 1.43 0.283 0.341 0.406 0.391 1.33 0.68 2.59 0.026 0.358 0.942 0.0259 1.03 0.509 2.07 0.495 0.326 0.13 0.8875 1.64 0.865 3.11 PRS_PLINK_1.99526231496888e.06 112 Candidiasis Both 1280 15203 1 infectious diseases blue 15203, 1280 3827, 297 3797, 318 3796, 330 3780, 333 0.0476 0.0288 0.0982 1.008 1.05 0.991 1.11 0.0713 0.0837 0.394 0.4042 1.07 0.911 1.27 0.118 0.0831 0.157 0.8052 1.12 0.956 1.32 0.13 0.0829 0.118 0.9271 1.14 0.968 1.34 PRS_PLINK_1.99526231496888e.06 117 Mycoses Both 142 1917 1 infectious diseases blue 1917, 142 479, 30 485, 30 474, 50 478, 32 0.0724 0.0845 0.392 0.4071 1.08 0.911 1.27 0.0236 0.262 0.928 0.03235 1.02 0.613 1.71 0.524 0.236 0.0263 1.58 1.69 1.06 2.68 0.0654 0.256 0.799 0.09767 1.07 0.646 1.76 PRS_PLINK_1.99526231496888e.06 117.4 Aspergillosis Both 85 1129 1 infectious diseases blue 1129, 85 284, 18 284, 18 279, 34 282, 15 0.0527 0.109 0.631 0.2003 1.05 0.85 1.31 0.00774 0.333 0.981 0.008138 1.01 0.525 1.93 0.621 0.294 0.0348 1.458 1.86 1.05 3.31 -0.172 0.344 0.617 0.2098 0.842 0.429 1.65 PRS_PLINK_1.99526231496888e.06 130 Spirochetal infection Both 54 603 1 infectious diseases blue 603, 54 153, 14 151, 16 148, 10 151, 14 0.0207 0.137 0.88 0.05543 1.02 0.78 1.34 0.114 0.369 0.757 0.1206 1.12 0.544 2.31 -0.215 0.408 0.599 0.2229 0.807 0.363 1.79 0.0707 0.383 0.854 0.06876 1.07 0.507 2.27 PRS_PLINK_1.99526231496888e.06 133 Arthropod-borne diseases Both 44 522 1 infectious diseases blue 522, 44 134, 8 127, 18 129, 5 131, 13 0.0539 0.151 0.721 0.1418 1.06 0.785 1.42 0.887 0.435 0.0414 1.383 2.43 1.04 5.7 -0.348 0.527 0.51 0.2928 0.706 0.252 1.98 0.422 0.447 0.345 0.4622 1.53 0.635 3.66 PRS_PLINK_1.99526231496888e.06 134 Helminthiases Both 85 996 1 infectious diseases blue 996, 85 250, 26 252, 16 245, 20 249, 23 0.0223 0.108 0.836 0.07798 1.02 0.828 1.26 -0.538 0.32 0.0928 1.032 0.584 0.312 1.09 -0.221 0.303 0.467 0.3309 0.802 0.442 1.45 -0.0749 0.297 0.801 0.09643 0.928 0.519 1.66 PRS_PLINK_1.99526231496888e.06 134.1 Intestinal helminthiases Both 70 838 1 infectious diseases blue 838, 70 211, 21 209, 15 211, 15 207, 19 -0.0105 0.122 0.932 0.03066 0.99 0.779 1.26 -0.344 0.34 0.312 0.506 0.709 0.364 1.38 -0.358 0.344 0.298 0.5259 0.699 0.356 1.37 0.0343 0.328 0.917 0.03773 1.03 0.544 1.97 PRS_PLINK_1.99526231496888e.06 136 Other infectious and parasitic diseases Both 124 1464 1 infectious diseases blue 1464, 124 366, 34 367, 27 365, 26 365, 37 0.0852 0.0902 0.345 0.4625 1.09 0.913 1.3 -0.236 0.263 0.369 0.4335 0.79 0.472 1.32 -0.266 0.264 0.314 0.5026 0.767 0.457 1.29 0.0762 0.245 0.756 0.1214 1.08 0.667 1.75 PRS_PLINK_1.99526231496888e.06 145 Cancer of mouth Both 440 4516 2 neoplasms darkcyan 4516, 440 1149, 110 1113, 118 1120, 105 1129, 106 -0.0385 0.05 0.441 0.3553 0.962 0.872 1.06 0.0983 0.139 0.478 0.3206 1.1 0.841 1.45 -0.0173 0.142 0.903 0.04438 0.983 0.744 1.3 -0.0163 0.142 0.908 0.04169 0.984 0.745 1.3 PRS_PLINK_1.99526231496888e.06 145.2 Cancer of tongue Both 217 2145 2 neoplasms darkcyan 2145, 217 546, 62 525, 62 537, 45 533, 48 -0.113 0.071 0.112 0.9501 0.893 0.777 1.03 0.00428 0.189 0.982 0.007926 1 0.694 1.45 -0.302 0.203 0.137 0.8648 0.739 0.497 1.1 -0.229 0.2 0.252 0.598 0.796 0.538 1.18 PRS_PLINK_1.99526231496888e.06 145.3 Cancer of major salivary glands Both 68 791 2 neoplasms darkcyan 791, 68 197, 12 198, 18 200, 19 195, 18 0.0983 0.123 0.422 0.3743 1.1 0.868 1.4 0.392 0.368 0.287 0.5419 1.48 0.719 3.05 0.465 0.368 0.206 0.6869 1.59 0.775 3.27 0.468 0.373 0.21 0.6773 1.6 0.768 3.32 PRS_PLINK_1.99526231496888e.06 145.5 Cancer of the mouth floor Both 37 369 2 neoplasms darkcyan 369, 37 94, 10 91, 10 92, 9 92, 8 -0.0162 0.174 0.926 0.03347 0.984 0.7 1.38 0.0423 0.452 0.925 0.03362 1.04 0.43 2.53 -0.152 0.466 0.745 0.1281 0.859 0.345 2.14 -0.121 0.469 0.796 0.0989 0.886 0.354 2.22 PRS_PLINK_1.99526231496888e.06 149 Cancer of larynx, pharynx, nasal cavities Both 392 4321 2 neoplasms darkcyan 4321, 392 1088, 107 1072, 102 1103, 93 1057, 89 -0.0834 0.0527 0.114 0.9443 0.92 0.83 1.02 -0.0307 0.144 0.832 0.08004 0.97 0.731 1.29 -0.138 0.147 0.348 0.4581 0.871 0.652 1.16 -0.14 0.149 0.35 0.456 0.87 0.649 1.17 PRS_PLINK_1.99526231496888e.06 149.1 Cancer of oropharynx Both 170 1800 2 neoplasms darkcyan 1800, 170 452, 51 452, 44 447, 43 449, 31 -0.155 0.082 0.0582 1.235 0.856 0.729 1.01 -0.195 0.215 0.366 0.4362 0.823 0.54 1.26 -0.149 0.215 0.488 0.3112 0.862 0.566 1.31 -0.508 0.235 0.0309 1.51 0.602 0.379 0.954 PRS_PLINK_1.99526231496888e.06 149.4 Cancer of larynx Both 140 1718 2 neoplasms darkcyan 1718, 140 438, 39 422, 29 428, 40 430, 32 -0.0419 0.0848 0.621 0.2066 0.959 0.812 1.13 -0.241 0.25 0.336 0.4742 0.786 0.481 1.28 0.0649 0.234 0.781 0.1072 1.07 0.675 1.69 -0.164 0.245 0.504 0.2976 0.849 0.525 1.37 PRS_PLINK_1.99526231496888e.06 149.9 Cancer of of nasal cavities Both 40 382 2 neoplasms darkcyan 382, 40 96, 9 96, 10 94, 8 96, 13 0.0219 0.16 0.891 0.05005 1.02 0.747 1.4 0.166 0.461 0.718 0.1437 1.18 0.478 2.92 -0.102 0.489 0.835 0.0781 0.903 0.347 2.36 0.327 0.433 0.451 0.3462 1.39 0.593 3.24 PRS_PLINK_1.99526231496888e.06 150 Cancer of esophagus Both 441 4965 2 neoplasms darkcyan 4965, 441 1252, 114 1238, 126 1256, 104 1218, 97 -0.0811 0.0503 0.107 0.9721 0.922 0.836 1.02 0.102 0.135 0.449 0.3474 1.11 0.85 1.44 -0.103 0.141 0.465 0.3324 0.902 0.685 1.19 -0.143 0.144 0.318 0.498 0.866 0.654 1.15 PRS_PLINK_1.99526231496888e.06 151 Cancer of stomach Both 331 3675 2 neoplasms darkcyan 3675, 331 925, 82 916, 86 917, 79 916, 83 0.0192 0.0565 0.734 0.1341 1.02 0.912 1.14 0.0395 0.16 0.805 0.09405 1.04 0.76 1.42 -0.0226 0.163 0.89 0.05075 0.978 0.71 1.35 0.0222 0.161 0.891 0.05033 1.02 0.745 1.4 PRS_PLINK_1.99526231496888e.06 153 Colorectal cancer Both 2982 31087 2 neoplasms darkcyan 31087, 2982 7774, 730 7759, 740 7780, 753 7762, 759 0.023 0.0189 0.223 0.6515 1.02 0.986 1.06 0.0166 0.0546 0.761 0.1184 1.02 0.914 1.13 0.0315 0.0543 0.562 0.2501 1.03 0.928 1.15 0.0418 0.0543 0.442 0.3547 1.04 0.937 1.16 PRS_PLINK_1.99526231496888e.06 153.2 Colon cancer Both 2015 20964 2 neoplasms darkcyan 20964, 2015 5247, 497 5233, 478 5239, 510 5235, 530 0.0447 0.0228 0.0501 1.3 1.05 1 1.09 -0.0362 0.0669 0.589 0.23 0.964 0.846 1.1 0.0278 0.0659 0.673 0.172 1.03 0.904 1.17 0.0681 0.0655 0.298 0.5259 1.07 0.942 1.22 PRS_PLINK_1.99526231496888e.06 153.3 Malignant neoplasm of rectum, rectosigmoid junction, and anus Both 1419 14778 2 neoplasms darkcyan 14778, 1419 3693, 343 3726, 378 3740, 368 3613, 330 -0.0195 0.0275 0.479 0.3195 0.981 0.929 1.04 0.0869 0.078 0.265 0.5766 1.09 0.936 1.27 0.0576 0.0784 0.462 0.335 1.06 0.908 1.24 -0.0187 0.0806 0.816 0.08817 0.981 0.838 1.15 PRS_PLINK_1.99526231496888e.06 155 Cancer of liver and intrahepatic bile duct Both 220 2702 2 neoplasms darkcyan 2702, 220 675, 46 679, 57 671, 56 676, 61 0.0585 0.0677 0.388 0.4112 1.06 0.928 1.21 0.186 0.203 0.361 0.4429 1.2 0.808 1.79 0.189 0.204 0.354 0.4504 1.21 0.81 1.8 0.299 0.201 0.136 0.8657 1.35 0.91 2 PRS_PLINK_1.99526231496888e.06 155.1 Malignant neoplasm of liver, primary Both 69 1024 2 neoplasms darkcyan 1024, 69 257, 15 255, 14 256, 23 255, 17 0.0606 0.118 0.609 0.2156 1.06 0.843 1.34 -0.00187 0.368 0.996 0.00177 0.998 0.486 2.05 0.419 0.334 0.21 0.6785 1.52 0.79 2.93 0.134 0.35 0.702 0.1539 1.14 0.576 2.27 PRS_PLINK_1.99526231496888e.06 157 Pancreatic cancer Both 398 4402 2 neoplasms darkcyan 4402, 398 1102, 111 1106, 91 1109, 98 1084, 97 -0.0348 0.0524 0.506 0.2959 0.966 0.872 1.07 -0.201 0.147 0.171 0.7671 0.818 0.613 1.09 -0.136 0.144 0.346 0.4604 0.873 0.658 1.16 -0.134 0.145 0.355 0.4499 0.874 0.658 1.16 PRS_PLINK_1.99526231496888e.06 158 Neoplasm of unspecified nature of digestive system Both 686 7382 2 neoplasms darkcyan 7382, 686 1841, 174 1865, 171 1825, 169 1846, 172 0.009 0.0398 0.821 0.08554 1.01 0.933 1.09 -0.0309 0.112 0.783 0.1063 0.97 0.778 1.21 -0.0207 0.113 0.854 0.06839 0.98 0.786 1.22 -0.00534 0.112 0.962 0.0168 0.995 0.798 1.24 PRS_PLINK_1.99526231496888e.06 159 Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum Both 3553 37731 2 neoplasms darkcyan 37731, 3553 9441, 866 9421, 898 9462, 909 9396, 880 0.00329 0.0174 0.85 0.07053 1 0.97 1.04 0.0377 0.0498 0.449 0.3473 1.04 0.942 1.14 0.0478 0.0497 0.336 0.474 1.05 0.952 1.16 0.024 0.0501 0.631 0.1998 1.02 0.929 1.13 PRS_PLINK_1.99526231496888e.06 159.2 Malignant neoplasm of small intestine, including duodenum Both 130 1326 2 neoplasms darkcyan 1326, 130 334, 27 330, 25 330, 45 332, 33 0.0965 0.0874 0.27 0.5693 1.1 0.928 1.31 -0.011 0.285 0.969 0.0136 0.989 0.566 1.73 0.516 0.251 0.0403 1.395 1.68 1.02 2.74 0.234 0.267 0.38 0.4197 1.26 0.749 2.14 PRS_PLINK_1.99526231496888e.06 159.3 Malignant neoplasm of gallbladder and extrahepatic bile ducts Both 131 1394 2 neoplasms darkcyan 1394, 131 348, 30 347, 39 353, 28 344, 34 -0.0604 0.0907 0.505 0.2965 0.941 0.788 1.12 0.291 0.251 0.247 0.6071 1.34 0.817 2.19 -0.106 0.269 0.695 0.158 0.9 0.531 1.53 0.152 0.258 0.555 0.256 1.16 0.703 1.93 PRS_PLINK_1.99526231496888e.06 159.4 Malignant neoplasm of retroperitoneum and peritoneum Both 122 1346 2 neoplasms darkcyan 1346, 122 340, 34 336, 30 333, 27 337, 31 -0.013 0.0914 0.887 0.05192 0.987 0.825 1.18 -0.118 0.257 0.647 0.1888 0.889 0.537 1.47 -0.192 0.264 0.466 0.3312 0.825 0.492 1.38 -0.101 0.255 0.694 0.1587 0.904 0.548 1.49 PRS_PLINK_1.99526231496888e.06 164 Cancer of intrathoracic organs Both 41 409 2 neoplasms darkcyan 409, 41 103, 11 102, 7 103, 10 101, 13 0.176 0.158 0.264 0.5786 1.19 0.876 1.62 -0.498 0.498 0.318 0.4978 0.608 0.229 1.61 0.0197 0.446 0.965 0.01555 1.02 0.425 2.45 0.27 0.425 0.526 0.279 1.31 0.569 3.01 PRS_PLINK_1.99526231496888e.06 165 Cancer within the respiratory system Both 1593 18688 2 neoplasms darkcyan 18688, 1593 4763, 403 4598, 391 4653, 387 4669, 412 0.00535 0.0256 0.835 0.07849 1.01 0.956 1.06 0.00658 0.0738 0.929 0.03202 1.01 0.871 1.16 -0.0141 0.074 0.849 0.07117 0.986 0.853 1.14 0.0459 0.073 0.529 0.2762 1.05 0.907 1.21 PRS_PLINK_1.99526231496888e.06 165.1 Cancer of bronchus; lung Both 1233 14797 2 neoplasms darkcyan 14797, 1233 3707, 293 3691, 297 3707, 303 3687, 340 0.0575 0.0288 0.0461 1.337 1.06 1 1.12 0.021 0.0854 0.806 0.09375 1.02 0.864 1.21 0.0368 0.085 0.665 0.1769 1.04 0.878 1.23 0.158 0.083 0.0568 1.246 1.17 0.995 1.38 PRS_PLINK_1.99526231496888e.06 170 Cancer of bone and connective tissue Both 295 3027 2 neoplasms darkcyan 3027, 295 765, 67 751, 79 756, 69 753, 80 0.0896 0.0602 0.137 0.8649 1.09 0.972 1.23 0.165 0.172 0.339 0.4696 1.18 0.841 1.65 0.0318 0.178 0.858 0.06642 1.03 0.729 1.46 0.177 0.172 0.303 0.5188 1.19 0.852 1.67 PRS_PLINK_1.99526231496888e.06 170.1 Bone cancer Both 84 899 2 neoplasms darkcyan 899, 84 227, 18 223, 16 225, 21 224, 29 0.262 0.109 0.0166 1.781 1.3 1.05 1.61 -0.111 0.344 0.747 0.1269 0.895 0.456 1.76 0.126 0.325 0.697 0.1566 1.13 0.6 2.14 0.49 0.306 0.11 0.9604 1.63 0.896 2.98 PRS_PLINK_1.99526231496888e.06 170.2 Cancer of connective tissue Both 225 2294 2 neoplasms darkcyan 2294, 225 576, 51 571, 69 579, 53 566, 52 0.028 0.07 0.689 0.1615 1.03 0.896 1.18 0.292 0.192 0.129 0.89 1.34 0.919 1.95 0.0237 0.202 0.907 0.04247 1.02 0.689 1.52 0.0333 0.204 0.87 0.06045 1.03 0.694 1.54 PRS_PLINK_1.99526231496888e.06 172 Skin cancer Both 9327 92779 2 neoplasms darkcyan 92779, 9327 23167, 2334 23212, 2428 23177, 2260 23194, 2303 -0.00898 0.0108 0.408 0.3897 0.991 0.97 1.01 0.0377 0.0304 0.216 0.6658 1.04 0.978 1.1 -0.0335 0.0309 0.279 0.5543 0.967 0.91 1.03 -0.0166 0.0308 0.591 0.2287 0.984 0.926 1.04 PRS_PLINK_1.99526231496888e.06 172.1 Melanomas of skin, dx or hx Both 1928 19087 2 neoplasms darkcyan 19087, 1928 4780, 482 4763, 521 4775, 481 4764, 443 -0.0403 0.0242 0.0964 1.016 0.961 0.916 1.01 0.0831 0.0664 0.211 0.6764 1.09 0.954 1.24 0.00544 0.0677 0.936 0.02875 1.01 0.881 1.15 -0.076 0.069 0.271 0.5677 0.927 0.81 1.06 PRS_PLINK_1.99526231496888e.06 172.11 Melanomas of skin Both 1951 19315 2 neoplasms darkcyan 19315, 1951 4846, 484 4813, 531 4837, 486 4814, 449 -0.0363 0.024 0.131 0.8816 0.964 0.92 1.01 0.101 0.066 0.124 0.9048 1.11 0.972 1.26 0.012 0.0674 0.858 0.06631 1.01 0.887 1.16 -0.0637 0.0687 0.354 0.4512 0.938 0.82 1.07 PRS_PLINK_1.99526231496888e.06 172.2 Other non-epithelial cancer of skin Both 7542 74823 2 neoplasms darkcyan 74823, 7542 18788, 1893 18630, 1966 18695, 1821 18686, 1861 -0.00824 0.012 0.493 0.3071 0.992 0.969 1.02 0.0464 0.0338 0.17 0.7685 1.05 0.98 1.12 -0.0354 0.0344 0.303 0.5179 0.965 0.902 1.03 -0.0149 0.0343 0.665 0.1774 0.985 0.921 1.05 PRS_PLINK_1.99526231496888e.06 172.3 Carcinoma in situ of skin Both 406 4415 2 neoplasms darkcyan 4415, 406 1106, 82 1104, 93 1109, 114 1096, 117 0.138 0.0504 0.00613 2.213 1.15 1.04 1.27 0.127 0.156 0.416 0.3808 1.14 0.836 1.54 0.325 0.15 0.0308 1.511 1.38 1.03 1.86 0.371 0.15 0.0131 1.883 1.45 1.08 1.94 PRS_PLINK_1.99526231496888e.06 173 Neoplasm of uncertain behavior of skin Both 128 1321 2 neoplasms darkcyan 1321, 128 329, 31 330, 33 340, 33 320, 31 -0.0239 0.0913 0.793 0.1006 0.976 0.816 1.17 0.0572 0.257 0.824 0.08407 1.06 0.64 1.75 0.0303 0.257 0.906 0.04284 1.03 0.623 1.71 0.0145 0.262 0.956 0.01968 1.01 0.607 1.69 PRS_PLINK_1.99526231496888e.06 174 Breast cancer Both 9487 97258 2 neoplasms darkcyan 97258, 9487 24514, 2347 24234, 2379 24412, 2402 24068, 2355 0.00916 0.0108 0.395 0.4031 1.01 0.988 1.03 0.024 0.0305 0.43 0.3663 1.02 0.965 1.09 0.0263 0.0304 0.386 0.413 1.03 0.967 1.09 0.0213 0.0306 0.486 0.3136 1.02 0.962 1.08 PRS_PLINK_1.99526231496888e.06 174.1 Breast cancer [female] Female 9353 95789 2 neoplasms darkcyan 95789, 9353 24131, 2321 23736, 2327 24229, 2383 23663, 2318 0.00807 0.0109 0.458 0.3395 1.01 0.987 1.03 0.0183 0.0307 0.552 0.2584 1.02 0.959 1.08 0.0216 0.0306 0.479 0.3197 1.02 0.962 1.08 0.0179 0.0308 0.561 0.2512 1.02 0.958 1.08 PRS_PLINK_1.99526231496888e.06 174.11 Malignant neoplasm of female breast Female 8789 90219 2 neoplasms darkcyan 90219, 8789 22742, 2156 22440, 2233 22645, 2225 22363, 2171 0.00601 0.0112 0.592 0.2279 1.01 0.984 1.03 0.048 0.0316 0.129 0.8898 1.05 0.986 1.12 0.0353 0.0316 0.265 0.5765 1.04 0.974 1.1 0.0233 0.0319 0.464 0.3338 1.02 0.962 1.09 PRS_PLINK_1.99526231496888e.06 174.3 Neoplasm of uncertain behavior of breast Both 93 905 2 neoplasms darkcyan 905, 93 227, 24 226, 22 226, 28 226, 19 0.0181 0.107 0.865 0.06302 1.02 0.826 1.26 -0.0481 0.305 0.875 0.05816 0.953 0.524 1.73 0.156 0.292 0.594 0.2261 1.17 0.659 2.07 -0.214 0.316 0.497 0.3036 0.807 0.435 1.5 PRS_PLINK_1.99526231496888e.06 175 Acquired absence of breast Female 1768 18613 2 neoplasms darkcyan 18613, 1768 4674, 416 4670, 464 4639, 459 4628, 429 -0.00375 0.0251 0.881 0.05488 0.996 0.948 1.05 0.111 0.0706 0.116 0.9361 1.12 0.973 1.28 0.115 0.0708 0.105 0.9775 1.12 0.976 1.29 0.0454 0.0719 0.528 0.2771 1.05 0.909 1.2 PRS_PLINK_1.99526231496888e.06 180 Cervical cancer and dysplasia Female 1779 18031 2 neoplasms darkcyan 18031, 1779 4521, 447 4537, 455 4481, 430 4487, 447 -0.000811 0.0251 0.974 0.01133 0.999 0.951 1.05 0.0122 0.0698 0.861 0.06485 1.01 0.883 1.16 -0.0298 0.0707 0.673 0.1718 0.971 0.845 1.11 0.00608 0.0701 0.931 0.03112 1.01 0.877 1.15 PRS_PLINK_1.99526231496888e.06 180.1 Cervical cancer Female 214 2176 2 neoplasms darkcyan 2176, 214 544, 62 544, 53 547, 43 540, 56 0.029 0.0716 0.686 0.1639 1.03 0.895 1.18 -0.159 0.195 0.413 0.3838 0.853 0.582 1.25 -0.352 0.205 0.0864 1.063 0.703 0.47 1.05 -0.0866 0.192 0.653 0.1854 0.917 0.629 1.34 PRS_PLINK_1.99526231496888e.06 180.3 Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia] Female 1703 17213 2 neoplasms darkcyan 17213, 1703 4342, 430 4283, 439 4300, 416 4284, 418 -0.0171 0.0258 0.507 0.2949 0.983 0.935 1.03 0.0333 0.0711 0.64 0.1942 1.03 0.899 1.19 -0.0229 0.072 0.751 0.1245 0.977 0.849 1.13 -0.015 0.072 0.835 0.07822 0.985 0.856 1.13 PRS_PLINK_1.99526231496888e.06 182 Malignant neoplasm of uterus Female 847 9520 2 neoplasms darkcyan 9520, 847 2432, 213 2340, 230 2367, 205 2377, 199 -0.0161 0.0361 0.655 0.184 0.984 0.917 1.06 0.116 0.0991 0.241 0.6178 1.12 0.925 1.36 -0.0102 0.102 0.92 0.03627 0.99 0.811 1.21 -0.0484 0.103 0.637 0.1957 0.953 0.779 1.16 PRS_PLINK_1.99526231496888e.06 184 Cancer of other female genital organs Female 1010 10505 2 neoplasms darkcyan 10505, 1010 2630, 240 2635, 287 2655, 244 2582, 239 -0.0141 0.033 0.669 0.1744 0.986 0.924 1.05 0.175 0.0915 0.0559 1.252 1.19 0.996 1.43 0.00528 0.0948 0.956 0.01974 1.01 0.835 1.21 0.0243 0.0955 0.799 0.09761 1.02 0.85 1.24 PRS_PLINK_1.99526231496888e.06 184.1 Malignant neoplasm of ovary and other uterine adnexa Female 715 7284 2 neoplasms darkcyan 7284, 715 1821, 171 1833, 196 1827, 185 1801, 163 -0.0294 0.0397 0.459 0.3381 0.971 0.898 1.05 0.131 0.109 0.231 0.636 1.14 0.92 1.41 0.0726 0.111 0.513 0.29 1.08 0.865 1.34 -0.0306 0.114 0.789 0.1031 0.97 0.775 1.21 PRS_PLINK_1.99526231496888e.06 184.11 Malignant neoplasm of ovary Female 693 7046 2 neoplasms darkcyan 7046, 693 1774, 173 1769, 182 1739, 175 1762, 163 -0.0371 0.0405 0.359 0.445 0.964 0.89 1.04 0.0556 0.111 0.617 0.2099 1.06 0.85 1.31 0.0295 0.112 0.793 0.1009 1.03 0.827 1.28 -0.0503 0.114 0.659 0.1812 0.951 0.76 1.19 PRS_PLINK_1.99526231496888e.06 184.2 Cancer of other female genital organs (excluding uterus and ovary) Female 219 2371 2 neoplasms darkcyan 2371, 219 595, 54 591, 69 594, 35 591, 61 -0.04 0.0712 0.574 0.2412 0.961 0.836 1.1 0.233 0.19 0.221 0.6554 1.26 0.869 1.83 -0.417 0.221 0.0595 1.225 0.659 0.427 1.02 0.157 0.195 0.42 0.3768 1.17 0.799 1.72 PRS_PLINK_1.99526231496888e.06 185 Cancer of prostate Male 3690 35865 2 neoplasms darkcyan 35865, 3690 9013, 912 8932, 883 9055, 962 8851, 932 0.0235 0.0169 0.164 0.7846 1.02 0.99 1.06 -0.0233 0.0495 0.638 0.1952 0.977 0.887 1.08 0.0463 0.0485 0.34 0.4687 1.05 0.952 1.15 0.0343 0.049 0.484 0.3151 1.03 0.94 1.14 PRS_PLINK_1.99526231496888e.06 187 Cancer of other male genital organs Male 304 3153 2 neoplasms darkcyan 3153, 304 788, 76 789, 70 788, 76 787, 82 0.0562 0.0577 0.331 0.4806 1.06 0.945 1.18 -0.0838 0.172 0.626 0.2032 0.92 0.656 1.29 9.55e-05 0.169 1 0.0001964 1 0.719 1.39 0.0753 0.167 0.652 0.1861 1.08 0.778 1.49 PRS_PLINK_1.99526231496888e.06 187.1 Malignant neoplasm of unspecified male genital organ Male 40 438 2 neoplasms darkcyan 438, 40 113, 10 106, 5 109, 9 110, 16 0.305 0.153 0.0466 1.332 1.36 1 1.83 -0.551 0.519 0.288 0.5404 0.576 0.209 1.59 -0.0394 0.461 0.932 0.03065 0.961 0.389 2.37 0.465 0.414 0.262 0.5814 1.59 0.706 3.59 PRS_PLINK_1.99526231496888e.06 187.2 Malignant neoplasm of testis Male 199 2112 2 neoplasms darkcyan 2112, 199 529, 46 532, 46 522, 57 528, 50 0.0323 0.0712 0.65 0.1869 1.03 0.898 1.19 0.00974 0.215 0.964 0.01594 1.01 0.662 1.54 0.233 0.206 0.258 0.5876 1.26 0.843 1.89 0.119 0.213 0.577 0.2385 1.13 0.742 1.71 PRS_PLINK_1.99526231496888e.06 187.8 Neoplasm of uncertain behavior of male genital organs Male 75 735 2 neoplasms darkcyan 735, 75 184, 24 184, 20 183, 11 184, 20 -0.096 0.118 0.417 0.3804 0.908 0.721 1.15 -0.166 0.315 0.598 0.2232 0.847 0.457 1.57 -0.7 0.365 0.0554 1.257 0.496 0.243 1.02 -0.179 0.316 0.573 0.2421 0.837 0.45 1.56 PRS_PLINK_1.99526231496888e.06 189 Cancer of urinary organs (incl. kidney and bladder) Both 2136 27012 2 neoplasms darkcyan 27012, 2136 6782, 502 6717, 535 6885, 551 6617, 547 0.0387 0.022 0.0789 1.103 1.04 0.996 1.09 0.0749 0.0644 0.245 0.6115 1.08 0.95 1.22 0.0764 0.0639 0.232 0.634 1.08 0.952 1.22 0.107 0.0641 0.0943 1.026 1.11 0.982 1.26 PRS_PLINK_1.99526231496888e.06 189.1 Cancer of kidney and renal pelvis Both 403 7221 2 neoplasms darkcyan 7221, 403 1815, 92 1793, 91 1806, 105 1804, 115 0.0907 0.049 0.0644 1.191 1.09 0.995 1.21 0.000743 0.15 0.996 0.001716 1 0.745 1.34 0.131 0.146 0.369 0.4335 1.14 0.857 1.52 0.224 0.143 0.116 0.9345 1.25 0.946 1.66 PRS_PLINK_1.99526231496888e.06 189.11 Malignant neoplasm of kidney, except pelvis Both 383 6951 2 neoplasms darkcyan 6951, 383 1762, 87 1716, 88 1735, 96 1735, 112 0.0929 0.0502 0.0643 1.191 1.1 0.994 1.21 0.0365 0.154 0.812 0.09029 1.04 0.767 1.4 0.106 0.151 0.482 0.317 1.11 0.828 1.49 0.264 0.146 0.0698 1.156 1.3 0.979 1.73 PRS_PLINK_1.99526231496888e.06 189.12 Malignant neoplasm of renal pelvis Both 31 434 2 neoplasms darkcyan 434, 31 111, 6 106, 9 108, 9 109, 7 0.0742 0.178 0.677 0.1696 1.08 0.76 1.53 0.356 0.504 0.479 0.3193 1.43 0.532 3.83 0.301 0.504 0.55 0.2594 1.35 0.503 3.63 0.0572 0.513 0.911 0.04038 1.06 0.387 2.9 PRS_PLINK_1.99526231496888e.06 189.2 Cancer of bladder Both 1356 15398 2 neoplasms darkcyan 15398, 1356 3861, 338 3838, 341 3865, 338 3828, 338 0.0117 0.028 0.676 0.1698 1.01 0.958 1.07 0.0127 0.0799 0.874 0.05873 1.01 0.866 1.18 -0.0043 0.0801 0.957 0.01901 0.996 0.851 1.16 0.00702 0.0801 0.93 0.03144 1.01 0.861 1.18 PRS_PLINK_1.99526231496888e.06 189.21 Malignant neoplasm of bladder Both 1195 13676 2 neoplasms darkcyan 13676, 1195 3422, 303 3414, 306 3490, 300 3345, 286 0.00286 0.0299 0.924 0.03454 1 0.946 1.06 0.00881 0.0844 0.917 0.03767 1.01 0.855 1.19 -0.0351 0.0848 0.679 0.168 0.966 0.818 1.14 -0.035 0.0858 0.683 0.1655 0.966 0.816 1.14 PRS_PLINK_1.99526231496888e.06 189.4 Malignant neoplasm of other urinary organs Both 58 938 2 neoplasms darkcyan 938, 58 237, 16 233, 10 236, 14 232, 18 0.0566 0.13 0.662 0.1788 1.06 0.821 1.36 -0.351 0.393 0.372 0.4291 0.704 0.326 1.52 -0.179 0.363 0.622 0.206 0.836 0.41 1.7 0.0804 0.346 0.816 0.0882 1.08 0.55 2.14 PRS_PLINK_1.99526231496888e.06 190 Cancer of eye Both 122 1233 2 neoplasms darkcyan 1233, 122 309, 38 308, 33 308, 22 308, 29 -0.094 0.0966 0.33 0.4809 0.91 0.753 1.1 -0.133 0.248 0.591 0.2284 0.875 0.539 1.42 -0.565 0.276 0.0408 1.39 0.568 0.331 0.977 -0.248 0.257 0.335 0.4749 0.781 0.472 1.29 PRS_PLINK_1.99526231496888e.06 191 Manlignant and unknown neoplasms of brain and nervous system Both 471 4848 2 neoplasms darkcyan 4848, 471 1209, 130 1216, 117 1208, 126 1212, 98 -0.0739 0.0492 0.133 0.8759 0.929 0.843 1.02 -0.107 0.133 0.422 0.3748 0.899 0.692 1.17 -0.0271 0.131 0.836 0.07775 0.973 0.753 1.26 -0.28 0.139 0.0438 1.358 0.755 0.575 0.992 PRS_PLINK_1.99526231496888e.06 191.1 Cancer of brain and nervous system Both 389 3944 2 neoplasms darkcyan 3944, 389 983, 107 992, 92 980, 108 986, 82 -0.054 0.054 0.317 0.4985 0.947 0.852 1.05 -0.162 0.148 0.273 0.5638 0.85 0.636 1.14 0.0153 0.143 0.915 0.03866 1.02 0.767 1.34 -0.273 0.153 0.0736 1.133 0.761 0.564 1.03 PRS_PLINK_1.99526231496888e.06 191.11 Cancer of brain Both 362 3669 2 neoplasms darkcyan 3669, 362 920, 97 912, 88 917, 102 917, 75 -0.0463 0.0558 0.407 0.3907 0.955 0.856 1.07 -0.0875 0.154 0.569 0.2449 0.916 0.678 1.24 0.0574 0.148 0.699 0.1556 1.06 0.792 1.42 -0.257 0.16 0.107 0.9694 0.773 0.565 1.06 PRS_PLINK_1.99526231496888e.06 193 Thyroid cancer Both 234 2652 2 neoplasms darkcyan 2652, 234 667, 53 663, 49 662, 59 660, 73 0.161 0.0648 0.013 1.887 1.17 1.03 1.33 -0.0755 0.203 0.71 0.1486 0.927 0.623 1.38 0.118 0.195 0.544 0.2646 1.13 0.768 1.65 0.352 0.188 0.0604 1.219 1.42 0.985 2.05 PRS_PLINK_1.99526231496888e.06 194 Cancer of other endocrine glands Both 58 701 2 neoplasms darkcyan 701, 58 177, 12 174, 20 175, 12 175, 14 -0.0589 0.138 0.67 0.1737 0.943 0.719 1.24 0.531 0.368 0.15 0.8248 1.7 0.826 3.5 0.133 0.412 0.746 0.1271 1.14 0.509 2.56 0.192 0.396 0.628 0.2023 1.21 0.558 2.63 PRS_PLINK_1.99526231496888e.06 195 Cancer, suspected or other Both 11114 116438 2 neoplasms darkcyan 116438, 11114 29236, 2768 29006, 2792 29140, 2793 29015, 2757 -0.000753 0.00988 0.939 0.02723 0.999 0.98 1.02 0.0151 0.0281 0.591 0.2284 1.02 0.961 1.07 0.00978 0.0281 0.728 0.1381 1.01 0.956 1.07 -0.000712 0.0282 0.98 0.008843 0.999 0.946 1.06 PRS_PLINK_1.99526231496888e.06 195.1 Malignant neoplasm, other Both 10621 111911 2 neoplasms darkcyan 111911, 10621 28070, 2650 27850, 2673 28010, 2662 27940, 2632 -0.00282 0.0101 0.78 0.1078 0.997 0.978 1.02 0.0153 0.0287 0.593 0.2271 1.02 0.96 1.07 0.00456 0.0287 0.874 0.05851 1 0.95 1.06 -0.00544 0.0288 0.85 0.07044 0.995 0.94 1.05 PRS_PLINK_1.99526231496888e.06 197 Chemotherapy Both 14014 156042 2 neoplasms darkcyan 156042, 14014 38972, 3444 39193, 3498 39115, 3540 38712, 3527 0.0127 0.00878 0.148 0.8292 1.01 0.995 1.03 0.00967 0.025 0.699 0.1553 1.01 0.961 1.06 0.0239 0.025 0.338 0.4713 1.02 0.975 1.08 0.031 0.025 0.216 0.6663 1.03 0.982 1.08 PRS_PLINK_1.99526231496888e.06 198 Secondary malignant neoplasm Both 6170 67750 2 neoplasms darkcyan 67750, 6170 17052, 1528 16900, 1519 16837, 1506 16938, 1613 0.0242 0.0132 0.0661 1.18 1.02 0.998 1.05 0.00419 0.0378 0.912 0.04014 1 0.932 1.08 -0.000123 0.0379 0.997 0.001128 1 0.928 1.08 0.0609 0.0374 0.103 0.9877 1.06 0.988 1.14 PRS_PLINK_1.99526231496888e.06 198.1 Secondary malignancy of lymph nodes Both 3642 38998 2 neoplasms darkcyan 38998, 3642 9746, 895 9794, 911 9741, 876 9708, 957 0.0318 0.0172 0.0642 1.193 1.03 0.998 1.07 0.0133 0.0492 0.787 0.1043 1.01 0.92 1.12 -0.0184 0.0496 0.711 0.1481 0.982 0.891 1.08 0.069 0.0487 0.156 0.8059 1.07 0.974 1.18 PRS_PLINK_1.99526231496888e.06 198.2 Secondary malignancy of respiratory organs Both 1380 15988 2 neoplasms darkcyan 15988, 1380 4011, 360 3980, 320 4001, 333 3992, 366 -0.00738 0.028 0.792 0.1012 0.993 0.94 1.05 -0.109 0.0799 0.172 0.7646 0.897 0.767 1.05 -0.0704 0.0792 0.374 0.4276 0.932 0.798 1.09 0.0186 0.0775 0.81 0.0914 1.02 0.875 1.19 PRS_PLINK_1.99526231496888e.06 198.3 Secondary malignant neoplasm of digestive systems Both 1009 11039 2 neoplasms darkcyan 11039, 1009 2759, 260 2756, 243 2761, 251 2758, 255 0.0138 0.0325 0.67 0.1738 1.01 0.951 1.08 -0.0693 0.093 0.456 0.3406 0.933 0.778 1.12 -0.0349 0.0923 0.705 0.1517 0.966 0.806 1.16 -0.0247 0.092 0.788 0.1034 0.976 0.815 1.17 PRS_PLINK_1.99526231496888e.06 198.4 Secondary malignant neoplasm of liver Both 1657 18449 2 neoplasms darkcyan 18449, 1657 4626, 408 4600, 381 4625, 431 4592, 436 0.03 0.0253 0.236 0.6273 1.03 0.981 1.08 -0.0621 0.0741 0.402 0.3958 0.94 0.813 1.09 0.0607 0.0721 0.4 0.3985 1.06 0.923 1.22 0.0738 0.072 0.305 0.5155 1.08 0.935 1.24 PRS_PLINK_1.99526231496888e.06 198.5 Secondary malignancy of brain/spine Both 527 6027 2 neoplasms darkcyan 6027, 527 1508, 131 1509, 136 1520, 135 1487, 125 -0.0117 0.0454 0.796 0.09891 0.988 0.904 1.08 0.0299 0.127 0.814 0.08947 1.03 0.803 1.32 0.031 0.128 0.808 0.09254 1.03 0.803 1.32 -0.0195 0.13 0.881 0.05515 0.981 0.761 1.26 PRS_PLINK_1.99526231496888e.06 198.6 Secondary malignancy of bone Both 1291 14889 2 neoplasms darkcyan 14889, 1291 3781, 321 3667, 302 3722, 305 3715, 363 0.0476 0.0285 0.0953 1.021 1.05 0.992 1.11 -0.0318 0.0833 0.703 0.1531 0.969 0.823 1.14 -0.0319 0.0831 0.701 0.1543 0.969 0.823 1.14 0.143 0.08 0.0747 1.127 1.15 0.986 1.35 PRS_PLINK_1.99526231496888e.06 198.7 Secondary malignant neoplasm of skin Both 119 1353 2 neoplasms darkcyan 1353, 119 341, 32 336, 37 337, 25 338, 25 -0.191 0.0994 0.0552 1.258 0.827 0.68 1 0.147 0.25 0.556 0.2549 1.16 0.71 1.89 -0.219 0.272 0.421 0.3761 0.803 0.472 1.37 -0.276 0.272 0.31 0.5092 0.759 0.445 1.29 PRS_PLINK_1.99526231496888e.06 199 Neoplasm of uncertain behavior Both 841 10306 2 neoplasms darkcyan 10306, 841 2597, 198 2571, 212 2574, 218 2561, 213 0.0447 0.0353 0.205 0.6881 1.05 0.976 1.12 0.0731 0.102 0.475 0.3233 1.08 0.88 1.31 0.11 0.102 0.281 0.5506 1.12 0.914 1.36 0.0908 0.102 0.375 0.4258 1.1 0.896 1.34 PRS_PLINK_1.99526231496888e.06 199.4 Neurofibromatosis Both 39 706 2 neoplasms darkcyan 706, 39 179, 7 175, 10 175, 12 177, 10 0.132 0.153 0.389 0.4103 1.14 0.845 1.54 0.387 0.46 0.4 0.3983 1.47 0.598 3.63 0.603 0.459 0.189 0.7233 1.83 0.743 4.49 0.345 0.469 0.461 0.3361 1.41 0.564 3.54 PRS_PLINK_1.99526231496888e.06 200 Myeloproliferative disease Both 480 6747 2 neoplasms darkcyan 6747, 480 1684, 104 1687, 117 1687, 126 1686, 133 0.0896 0.046 0.0512 1.291 1.09 1 1.2 0.124 0.138 0.368 0.4343 1.13 0.864 1.49 0.206 0.136 0.131 0.8812 1.23 0.94 1.61 0.269 0.135 0.0469 1.328 1.31 1 1.7 PRS_PLINK_1.99526231496888e.06 200.1 Polycythemia vera Both 162 2584 2 neoplasms darkcyan 2584, 162 651, 34 640, 33 646, 49 645, 46 0.158 0.0771 0.0405 1.392 1.17 1.01 1.36 -0.00519 0.245 0.983 0.007394 0.995 0.615 1.61 0.388 0.227 0.0872 1.059 1.47 0.945 2.3 0.327 0.23 0.155 0.8096 1.39 0.884 2.17 PRS_PLINK_1.99526231496888e.06 201 Hodgkin's disease Both 160 1976 2 neoplasms darkcyan 1976, 160 494, 43 496, 40 494, 46 492, 31 -0.053 0.0828 0.522 0.2825 0.948 0.806 1.12 -0.0707 0.225 0.754 0.1229 0.932 0.599 1.45 0.0903 0.219 0.68 0.1677 1.09 0.713 1.68 -0.317 0.24 0.186 0.7307 0.728 0.455 1.17 PRS_PLINK_1.99526231496888e.06 202 Cancer of other lymphoid, histiocytic tissue Both 1288 15846 2 neoplasms darkcyan 15846, 1288 3958, 302 3958, 320 3965, 313 3958, 353 0.0444 0.0282 0.115 0.9397 1.05 0.989 1.1 0.0582 0.0832 0.484 0.3151 1.06 0.901 1.25 0.0376 0.0836 0.653 0.1851 1.04 0.881 1.22 0.164 0.0816 0.044 1.356 1.18 1 1.38 PRS_PLINK_1.99526231496888e.06 202.2 Non-Hodgkins lymphoma Both 1012 12512 2 neoplasms darkcyan 12512, 1012 3121, 236 3158, 260 3109, 240 3117, 276 0.0484 0.0316 0.125 0.9024 1.05 0.987 1.12 0.086 0.0932 0.356 0.4485 1.09 0.908 1.31 0.0208 0.095 0.826 0.08276 1.02 0.848 1.23 0.168 0.0923 0.0683 1.165 1.18 0.987 1.42 PRS_PLINK_1.99526231496888e.06 202.21 Nodular lymphoma Both 220 2507 2 neoplasms darkcyan 2507, 220 633, 46 627, 51 620, 56 627, 67 0.154 0.0666 0.0205 1.689 1.17 1.02 1.33 0.0981 0.208 0.637 0.1957 1.1 0.734 1.66 0.218 0.205 0.288 0.5406 1.24 0.832 1.86 0.378 0.199 0.057 1.244 1.46 0.989 2.15 PRS_PLINK_1.99526231496888e.06 202.24 Large cell lymphoma Both 328 4022 2 neoplasms darkcyan 4022, 328 1008, 75 1003, 75 1005, 80 1005, 98 0.0998 0.0549 0.0693 1.16 1.1 0.992 1.23 0.0188 0.168 0.911 0.0406 1.02 0.733 1.42 0.05 0.166 0.763 0.1174 1.05 0.759 1.46 0.272 0.159 0.0868 1.062 1.31 0.962 1.79 PRS_PLINK_1.99526231496888e.06 204 Leukemia Both 926 11320 2 neoplasms darkcyan 11320, 926 2841, 213 2821, 207 2826, 265 2828, 241 0.046 0.0337 0.173 0.763 1.05 0.98 1.12 -0.0236 0.101 0.815 0.08899 0.977 0.801 1.19 0.22 0.0955 0.0215 1.667 1.25 1.03 1.5 0.122 0.0976 0.21 0.6776 1.13 0.933 1.37 PRS_PLINK_1.99526231496888e.06 204.1 Lymphoid leukemia Both 317 3872 2 neoplasms darkcyan 3872, 317 967, 73 968, 67 990, 91 946, 86 0.0838 0.0564 0.138 0.8608 1.09 0.973 1.21 -0.088 0.174 0.612 0.213 0.916 0.652 1.29 0.189 0.162 0.244 0.6123 1.21 0.879 1.66 0.176 0.164 0.285 0.5455 1.19 0.864 1.65 PRS_PLINK_1.99526231496888e.06 204.11 Lymphoid leukemia, acute Both 34 413 2 neoplasms darkcyan 413, 34 103, 10 103, 7 103, 8 103, 9 0.0483 0.182 0.79 0.1022 1.05 0.735 1.5 -0.286 0.474 0.547 0.2621 0.752 0.297 1.9 -0.209 0.465 0.653 0.185 0.811 0.326 2.02 -0.0515 0.457 0.91 0.04081 0.95 0.388 2.33 PRS_PLINK_1.99526231496888e.06 204.12 Lymphoid leukemia, chronic Both 270 3393 2 neoplasms darkcyan 3393, 270 857, 59 841, 57 855, 81 840, 73 0.0929 0.0607 0.126 0.8999 1.1 0.974 1.24 -0.018 0.19 0.925 0.03405 0.982 0.677 1.43 0.304 0.176 0.0848 1.072 1.36 0.959 1.92 0.217 0.18 0.228 0.6421 1.24 0.873 1.77 PRS_PLINK_1.99526231496888e.06 204.2 Myeloid leukemia Both 271 3228 2 neoplasms darkcyan 3228, 271 812, 60 802, 54 812, 92 802, 65 0.073 0.0615 0.235 0.629 1.08 0.954 1.21 -0.105 0.192 0.585 0.2332 0.9 0.618 1.31 0.441 0.172 0.0104 1.983 1.55 1.11 2.18 0.0751 0.184 0.684 0.1649 1.08 0.751 1.55 PRS_PLINK_1.99526231496888e.06 204.21 Myeloid leukemia, acute Both 182 2296 2 neoplasms darkcyan 2296, 182 574, 45 575, 30 581, 60 565, 47 0.0936 0.074 0.206 0.6858 1.1 0.95 1.27 -0.393 0.238 0.0987 1.006 0.675 0.423 1.08 0.294 0.204 0.151 0.8217 1.34 0.899 2 0.0426 0.214 0.842 0.07444 1.04 0.686 1.59 PRS_PLINK_1.99526231496888e.06 204.22 Myeloid leukemia, chronic Both 103 1010 2 neoplasms darkcyan 1010, 103 253, 16 252, 23 255, 38 250, 26 0.128 0.0995 0.198 0.7044 1.14 0.935 1.38 0.31 0.329 0.345 0.4621 1.36 0.716 2.6 0.835 0.303 0.00585 2.233 2.31 1.27 4.18 0.491 0.322 0.128 0.8937 1.63 0.869 3.07 PRS_PLINK_1.99526231496888e.06 204.4 Multiple myeloma Both 287 3744 2 neoplasms darkcyan 3744, 287 941, 71 930, 69 936, 85 936, 62 -0.0482 0.062 0.437 0.3592 0.953 0.844 1.08 -0.0241 0.174 0.89 0.05073 0.976 0.694 1.37 0.161 0.166 0.334 0.4761 1.17 0.848 1.63 -0.148 0.179 0.407 0.3905 0.862 0.608 1.22 PRS_PLINK_1.99526231496888e.06 208 Benign neoplasm of colon Both 12795 134394 2 neoplasms darkcyan 134394, 12795 33722, 3183 33560, 3151 33593, 3254 33474, 3201 0.00549 0.00919 0.55 0.2596 1.01 0.988 1.02 -0.00601 0.0263 0.819 0.08657 0.994 0.944 1.05 0.0245 0.0261 0.348 0.4587 1.02 0.974 1.08 0.00942 0.0262 0.719 0.1431 1.01 0.959 1.06 PRS_PLINK_1.99526231496888e.06 210 Benign neoplasm of lip, oral cavity, and pharynx Both 681 7213 2 neoplasms darkcyan 7213, 681 1804, 170 1807, 182 1816, 150 1784, 178 -0.0212 0.0397 0.594 0.226 0.979 0.906 1.06 0.0636 0.111 0.568 0.2456 1.07 0.857 1.33 -0.129 0.116 0.266 0.5744 0.879 0.699 1.1 0.0579 0.112 0.606 0.2178 1.06 0.851 1.32 PRS_PLINK_1.99526231496888e.06 211 Benign neoplasm of other parts of digestive system Both 3571 37441 2 neoplasms darkcyan 37441, 3571 9423, 888 9293, 805 9467, 909 9246, 966 0.0499 0.0172 0.00374 2.427 1.05 1.02 1.09 -0.0849 0.0508 0.0945 1.025 0.919 0.832 1.01 0.0176 0.0494 0.722 0.1414 1.02 0.924 1.12 0.106 0.0488 0.0299 1.524 1.11 1.01 1.22 PRS_PLINK_1.99526231496888e.06 212 Benign neoplasm of respiratory and intrathoracic organs Both 234 2505 2 neoplasms darkcyan 2505, 234 626, 50 631, 60 622, 70 625, 54 0.00852 0.0679 0.9 0.0457 1.01 0.883 1.15 0.179 0.197 0.364 0.4393 1.2 0.813 1.76 0.341 0.191 0.0747 1.127 1.41 0.967 2.05 0.0666 0.202 0.742 0.1299 1.07 0.72 1.59 PRS_PLINK_1.99526231496888e.06 213 Benign neoplasm of bone and articular cartilage Both 244 2393 2 neoplasms darkcyan 2393, 244 609, 63 591, 62 597, 61 596, 58 -0.00852 0.0681 0.9 0.04559 0.992 0.868 1.13 0.0215 0.186 0.908 0.04187 1.02 0.709 1.47 -0.0259 0.188 0.89 0.0504 0.974 0.674 1.41 -0.0636 0.19 0.738 0.1322 0.938 0.647 1.36 PRS_PLINK_1.99526231496888e.06 214 Lipoma Both 4392 45251 2 neoplasms darkcyan 45251, 4392 11324, 1123 11313, 1080 11415, 1074 11185, 1115 0.0106 0.0156 0.497 0.304 1.01 0.98 1.04 -0.0382 0.0446 0.391 0.4074 0.962 0.882 1.05 -0.0527 0.0447 0.239 0.6225 0.949 0.869 1.04 0.00778 0.0444 0.861 0.06513 1.01 0.924 1.1 PRS_PLINK_1.99526231496888e.06 214.1 Lipoma of skin and subcutaneous tissue Both 3277 33835 2 neoplasms darkcyan 33835, 3277 8463, 825 8507, 816 8399, 791 8459, 845 0.0165 0.0181 0.363 0.4407 1.02 0.981 1.05 -0.0176 0.0517 0.734 0.1344 0.983 0.888 1.09 -0.0329 0.0521 0.528 0.2776 0.968 0.874 1.07 0.0256 0.0513 0.618 0.2088 1.03 0.928 1.13 PRS_PLINK_1.99526231496888e.06 215 Other benign neoplasm of connective and other soft tissue Both 820 8233 2 neoplasms darkcyan 8233, 820 2057, 172 2064, 209 2077, 217 2032, 222 0.104 0.036 0.00389 2.41 1.11 1.03 1.19 0.186 0.107 0.0829 1.081 1.2 0.976 1.49 0.221 0.106 0.0375 1.426 1.25 1.01 1.54 0.269 0.106 0.0111 1.954 1.31 1.06 1.61 PRS_PLINK_1.99526231496888e.06 216 Benign neoplasm of skin Both 5724 57581 2 neoplasms darkcyan 57581, 5724 14473, 1464 14471, 1433 14290, 1374 14326, 1450 0.00163 0.0139 0.906 0.04266 1 0.975 1.03 -0.0214 0.039 0.583 0.2347 0.979 0.907 1.06 -0.051 0.0394 0.195 0.7098 0.95 0.88 1.03 0.00428 0.0389 0.912 0.03982 1 0.931 1.08 PRS_PLINK_1.99526231496888e.06 217 Vascular hamartomas and non-neoplastic nevi Both 435 4529 2 neoplasms darkcyan 4529, 435 1133, 116 1132, 95 1137, 116 1125, 108 0.0159 0.0496 0.749 0.1256 1.02 0.922 1.12 -0.197 0.144 0.17 0.7691 0.821 0.62 1.09 -0.00046 0.137 0.997 0.001165 1 0.764 1.31 -0.0703 0.14 0.615 0.2114 0.932 0.709 1.23 PRS_PLINK_1.99526231496888e.06 217.1 Nevus, non-neoplastic Both 409 4246 2 neoplasms darkcyan 4246, 409 1076, 107 1051, 97 1055, 103 1062, 102 0.0128 0.0509 0.802 0.09581 1.01 0.917 1.12 -0.0773 0.146 0.596 0.2249 0.926 0.696 1.23 -0.0101 0.144 0.944 0.02511 0.99 0.747 1.31 -0.0334 0.144 0.817 0.08786 0.967 0.729 1.28 PRS_PLINK_1.99526231496888e.06 218 Benign neoplasm of uterus Female 8074 81251 2 neoplasms darkcyan 81251, 8074 20623, 2034 19988, 2083 20310, 1973 20309, 1981 -0.00909 0.0118 0.441 0.3554 0.991 0.968 1.01 0.0562 0.0327 0.0857 1.067 1.06 0.992 1.13 -0.0163 0.0331 0.622 0.2059 0.984 0.922 1.05 -0.00792 0.0331 0.811 0.091 0.992 0.93 1.06 PRS_PLINK_1.99526231496888e.06 218.1 Uterine leiomyoma Female 8240 82633 2 neoplasms darkcyan 82633, 8240 20925, 2055 20385, 2161 20675, 1999 20628, 2022 -0.00953 0.0117 0.415 0.3823 0.991 0.968 1.01 0.0778 0.0323 0.0161 1.793 1.08 1.01 1.15 -0.0171 0.0329 0.602 0.2201 0.983 0.922 1.05 0.000341 0.0329 0.992 0.00361 1 0.938 1.07 PRS_PLINK_1.99526231496888e.06 218.2 Other benign neoplasm of uterus Female 269 2832 2 neoplasms darkcyan 2832, 269 709, 83 709, 56 714, 69 700, 61 -0.0974 0.0647 0.132 0.878 0.907 0.799 1.03 -0.386 0.179 0.0316 1.5 0.68 0.478 0.967 -0.192 0.17 0.261 0.584 0.826 0.591 1.15 -0.285 0.176 0.106 0.9751 0.752 0.533 1.06 PRS_PLINK_1.99526231496888e.06 220 Benign neoplasm of ovary Female 1120 11458 2 neoplasms darkcyan 11458, 1120 2879, 294 2848, 257 2864, 283 2865, 286 -0.0118 0.0318 0.71 0.1489 0.988 0.928 1.05 -0.12 0.0892 0.179 0.7482 0.887 0.745 1.06 -0.0306 0.0872 0.725 0.1395 0.97 0.817 1.15 -0.0189 0.0871 0.829 0.08168 0.981 0.827 1.16 PRS_PLINK_1.99526231496888e.06 221 Benign neoplasm of other female genital organs Female 173 1750 2 neoplasms darkcyan 1750, 173 442, 49 435, 44 436, 42 437, 38 -0.123 0.081 0.128 0.892 0.884 0.754 1.04 -0.0963 0.216 0.656 0.183 0.908 0.595 1.39 -0.133 0.218 0.541 0.2668 0.875 0.571 1.34 -0.241 0.224 0.281 0.5506 0.786 0.507 1.22 PRS_PLINK_1.99526231496888e.06 222 Benign neoplasm of male genital organs Male 94 1038 2 neoplasms darkcyan 1038, 94 262, 13 261, 20 255, 26 260, 35 0.297 0.102 0.00345 2.463 1.35 1.1 1.64 0.453 0.353 0.2 0.6997 1.57 0.787 3.14 0.719 0.34 0.0345 1.462 2.05 1.05 4 0.978 0.326 0.0027 2.569 2.66 1.4 5.04 PRS_PLINK_1.99526231496888e.06 223 Benign neoplasm of kidney and other urinary organs Both 100 1152 2 neoplasms darkcyan 1152, 100 288, 19 289, 25 288, 24 286, 32 0.198 0.0957 0.0383 1.417 1.22 1.01 1.47 0.324 0.309 0.293 0.5327 1.38 0.755 2.53 0.286 0.311 0.359 0.445 1.33 0.723 2.45 0.507 0.295 0.0861 1.065 1.66 0.931 2.96 PRS_PLINK_1.99526231496888e.06 224 Benign neoplasm of eye Both 78 954 2 neoplasms darkcyan 954, 78 240, 13 237, 19 243, 20 234, 25 0.236 0.11 0.0317 1.498 1.27 1.02 1.57 0.408 0.359 0.256 0.5924 1.5 0.744 3.04 0.376 0.353 0.287 0.5422 1.46 0.729 2.91 0.701 0.346 0.0427 1.369 2.02 1.02 3.97 PRS_PLINK_1.99526231496888e.06 224.1 Benign neoplasm of eye, uveal Both 37 458 2 neoplasms darkcyan 458, 37 115, 6 114, 7 114, 11 115, 13 0.366 0.16 0.0219 1.659 1.44 1.05 1.97 0.197 0.525 0.707 0.1507 1.22 0.436 3.41 0.603 0.484 0.212 0.6733 1.83 0.709 4.72 0.629 0.481 0.191 0.7192 1.88 0.731 4.82 PRS_PLINK_1.99526231496888e.06 225 Benign neoplasm of brain and other parts of nervous system Both 563 5999 2 neoplasms darkcyan 5999, 563 1506, 148 1496, 153 1510, 138 1486, 124 -0.0598 0.0449 0.183 0.7377 0.942 0.863 1.03 0.0382 0.12 0.751 0.1241 1.04 0.82 1.32 -0.066 0.123 0.592 0.2273 0.936 0.735 1.19 -0.168 0.127 0.186 0.7309 0.846 0.66 1.08 PRS_PLINK_1.99526231496888e.06 225.1 Benign neoplasm of brain, cranial nerves, meninges Both 528 5694 2 neoplasms darkcyan 5694, 528 1429, 140 1428, 144 1436, 127 1400, 117 -0.0462 0.0459 0.314 0.5028 0.955 0.873 1.04 0.0257 0.124 0.836 0.07786 1.03 0.805 1.31 -0.1 0.128 0.433 0.3639 0.905 0.705 1.16 -0.161 0.13 0.218 0.6621 0.851 0.659 1.1 PRS_PLINK_1.99526231496888e.06 225.2 Benign neoplasm of spinal cord, meninges Both 43 455 2 neoplasms darkcyan 455, 43 115, 9 113, 13 114, 14 113, 7 -0.07 0.165 0.671 0.1735 0.932 0.675 1.29 0.259 0.444 0.559 0.2524 1.3 0.543 3.09 0.354 0.423 0.403 0.3951 1.42 0.622 3.26 -0.271 0.5 0.587 0.2311 0.762 0.286 2.03 PRS_PLINK_1.99526231496888e.06 226 Benign neoplasm of thyroid glands Both 196 2039 2 neoplasms darkcyan 2039, 196 511, 70 508, 40 507, 39 510, 47 -0.139 0.0781 0.0744 1.129 0.87 0.747 1.01 -0.566 0.206 0.00603 2.22 0.568 0.379 0.851 -0.598 0.209 0.00419 2.377 0.55 0.365 0.828 -0.376 0.197 0.0564 1.248 0.686 0.466 1.01 PRS_PLINK_1.99526231496888e.06 227 Benign neoplasm of other endocrine glands and related structures Both 548 6287 2 neoplasms darkcyan 6287, 548 1583, 124 1567, 153 1577, 135 1557, 136 0.0388 0.0437 0.374 0.4268 1.04 0.954 1.13 0.227 0.125 0.0705 1.152 1.25 0.981 1.6 0.0867 0.129 0.501 0.3004 1.09 0.847 1.4 0.114 0.129 0.375 0.426 1.12 0.871 1.44 PRS_PLINK_1.99526231496888e.06 227.1 Benign neoplasm of adrenal gland Both 106 1354 2 neoplasms darkcyan 1354, 106 341, 18 337, 29 341, 31 335, 28 0.107 0.0958 0.264 0.5787 1.11 0.922 1.34 0.565 0.304 0.0625 1.204 1.76 0.971 3.19 0.538 0.3 0.0729 1.137 1.71 0.951 3.08 0.471 0.302 0.119 0.9233 1.6 0.885 2.9 PRS_PLINK_1.99526231496888e.06 227.2 Benign neoplasm of parathyroid gland Both 237 2662 2 neoplasms darkcyan 2662, 237 665, 55 672, 64 670, 57 654, 61 0.0535 0.0656 0.414 0.3826 1.05 0.928 1.2 0.146 0.19 0.441 0.3554 1.16 0.798 1.68 0.026 0.195 0.894 0.0488 1.03 0.701 1.5 0.107 0.192 0.576 0.2396 1.11 0.764 1.62 PRS_PLINK_1.99526231496888e.06 227.3 Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch) Both 204 2262 2 neoplasms darkcyan 2262, 204 571, 51 565, 53 561, 49 565, 51 0.0151 0.0739 0.838 0.07678 1.02 0.878 1.17 0.046 0.202 0.82 0.08604 1.05 0.704 1.56 -0.0531 0.207 0.797 0.09845 0.948 0.632 1.42 -0.00375 0.205 0.985 0.00638 0.996 0.667 1.49 PRS_PLINK_1.99526231496888e.06 228 Hemangioma and lymphangioma, any site Both 1141 11659 2 neoplasms darkcyan 11659, 1141 2915, 305 2930, 294 2899, 292 2912, 246 -0.0641 0.0314 0.0413 1.384 0.938 0.882 0.997 -0.0416 0.0857 0.627 0.2026 0.959 0.811 1.13 -0.0378 0.0858 0.659 0.1809 0.963 0.814 1.14 -0.222 0.0895 0.013 1.887 0.801 0.672 0.954 PRS_PLINK_1.99526231496888e.06 229 Benign neoplasm of unspecified sites Both 1842 18187 2 neoplasms darkcyan 18187, 1842 4586, 474 4548, 434 4546, 455 4496, 479 0.0206 0.0244 0.399 0.3995 1.02 0.973 1.07 -0.0771 0.0696 0.268 0.5719 0.926 0.808 1.06 -0.0316 0.0688 0.646 0.1899 0.969 0.847 1.11 0.0303 0.0681 0.656 0.1829 1.03 0.902 1.18 PRS_PLINK_1.99526231496888e.06 240 Simple and unspecified goiter Both 414 4535 3 endocrine/metabolic brown 4535, 414 1149, 90 1118, 97 1139, 120 1128, 107 0.0938 0.0501 0.0611 1.214 1.1 0.996 1.21 0.0985 0.151 0.514 0.2887 1.1 0.821 1.48 0.296 0.145 0.0407 1.39 1.34 1.01 1.79 0.193 0.148 0.192 0.7163 1.21 0.907 1.62 PRS_PLINK_1.99526231496888e.06 241 Nontoxic nodular goiter Both 779 8411 3 endocrine/metabolic brown 8411, 779 2131, 218 2078, 200 2119, 161 2082, 200 -0.0185 0.0377 0.623 0.2052 0.982 0.912 1.06 -0.0614 0.102 0.548 0.261 0.94 0.77 1.15 -0.298 0.108 0.00579 2.238 0.742 0.601 0.917 -0.0541 0.103 0.598 0.2233 0.947 0.775 1.16 PRS_PLINK_1.99526231496888e.06 241.1 Nontoxic uninodular goiter Both 357 3598 3 endocrine/metabolic brown 3598, 357 903, 89 896, 81 900, 83 898, 104 0.0949 0.0552 0.0856 1.067 1.1 0.987 1.23 -0.0816 0.159 0.609 0.2157 0.922 0.674 1.26 -0.0655 0.159 0.68 0.1676 0.937 0.686 1.28 0.176 0.151 0.245 0.6109 1.19 0.886 1.6 PRS_PLINK_1.99526231496888e.06 241.2 Nontoxic multinodular goiter Both 451 5090 3 endocrine/metabolic brown 5090, 451 1301, 133 1245, 128 1279, 88 1265, 102 -0.0994 0.0499 0.0464 1.333 0.905 0.821 0.998 0.00877 0.129 0.946 0.02412 1.01 0.783 1.3 -0.399 0.142 0.00497 2.304 0.671 0.508 0.886 -0.233 0.137 0.0888 1.052 0.792 0.606 1.04 PRS_PLINK_1.99526231496888e.06 242 Thyrotoxicosis with or without goiter Both 1162 13999 3 endocrine/metabolic brown 13999, 1162 3515, 282 3482, 292 3559, 297 3440, 291 0.0363 0.0303 0.231 0.6363 1.04 0.977 1.1 0.044 0.0867 0.611 0.2137 1.05 0.882 1.24 0.0422 0.0863 0.625 0.2045 1.04 0.881 1.24 0.054 0.0868 0.534 0.2727 1.06 0.89 1.25 PRS_PLINK_1.99526231496888e.06 242.1 Graves' disease Both 327 3632 3 endocrine/metabolic brown 3632, 327 909, 73 910, 96 911, 79 899, 79 0.00266 0.0577 0.963 0.01628 1 0.895 1.12 0.267 0.161 0.0971 1.013 1.31 0.953 1.79 0.0788 0.168 0.638 0.195 1.08 0.779 1.5 0.103 0.168 0.541 0.2664 1.11 0.797 1.54 PRS_PLINK_1.99526231496888e.06 242.2 Toxic multinodular goiter Both 57 715 3 endocrine/metabolic brown 715, 57 180, 11 179, 14 177, 18 179, 14 0.118 0.126 0.35 0.4558 1.13 0.879 1.44 0.17 0.401 0.672 0.1725 1.18 0.54 2.6 0.504 0.383 0.188 0.7262 1.66 0.782 3.51 0.265 0.399 0.506 0.2959 1.3 0.597 2.85 PRS_PLINK_1.99526231496888e.06 242.3 Exophthalmos Both 95 1059 3 endocrine/metabolic brown 1059, 95 274, 21 258, 30 267, 21 260, 23 -0.00761 0.108 0.944 0.02502 0.992 0.803 1.23 0.395 0.291 0.175 0.7563 1.48 0.839 2.63 0.0198 0.309 0.949 0.02273 1.02 0.557 1.87 0.17 0.308 0.581 0.2357 1.19 0.648 2.17 PRS_PLINK_1.99526231496888e.06 244 Hypothyroidism Both 9219 108660 3 endocrine/metabolic brown 108660, 9219 27215, 2339 27163, 2087 27227, 2453 27023, 2335 0.0249 0.0108 0.0213 1.671 1.03 1 1.05 -0.112 0.0313 0.000366 3.437 0.894 0.841 0.951 0.0497 0.0302 0.0991 1.004 1.05 0.991 1.11 0.00859 0.0305 0.778 0.1088 1.01 0.95 1.07 PRS_PLINK_1.99526231496888e.06 244.1 Secondary hypothyroidism Both 700 8273 3 endocrine/metabolic brown 8273, 700 2108, 154 2048, 168 2047, 191 2068, 187 0.0669 0.0386 0.083 1.081 1.07 0.991 1.15 0.114 0.115 0.325 0.4885 1.12 0.894 1.4 0.241 0.112 0.0314 1.503 1.27 1.02 1.59 0.217 0.113 0.0546 1.263 1.24 0.996 1.55 PRS_PLINK_1.99526231496888e.06 244.2 Acquired hypothyroidism Both 60 769 3 endocrine/metabolic brown 769, 60 195, 17 194, 15 188, 14 192, 14 -0.0663 0.137 0.628 0.2017 0.936 0.715 1.22 -0.142 0.354 0.688 0.1622 0.868 0.433 1.74 -0.118 0.36 0.742 0.1295 0.888 0.439 1.8 -0.19 0.359 0.596 0.2249 0.827 0.409 1.67 PRS_PLINK_1.99526231496888e.06 244.4 Hypothyroidism NOS Both 8765 103937 3 endocrine/metabolic brown 103937, 8765 26029, 2235 25914, 1973 26083, 2341 25879, 2211 0.0228 0.0111 0.04 1.398 1.02 1 1.05 -0.119 0.0321 0.000207 3.685 0.888 0.834 0.945 0.0476 0.0309 0.123 0.9113 1.05 0.987 1.11 -0.000918 0.0313 0.977 0.01028 0.999 0.94 1.06 PRS_PLINK_1.99526231496888e.06 245 Thyroiditis Both 201 2279 3 endocrine/metabolic brown 2279, 201 584, 58 556, 53 575, 50 561, 40 -0.118 0.0745 0.114 0.943 0.889 0.768 1.03 -0.0406 0.197 0.837 0.07733 0.96 0.652 1.41 -0.126 0.2 0.528 0.2772 0.881 0.596 1.3 -0.321 0.211 0.128 0.8926 0.726 0.48 1.1 PRS_PLINK_1.99526231496888e.06 245.2 Chronic thyroiditis Both 153 1716 3 endocrine/metabolic brown 1716, 153 437, 46 422, 41 431, 32 426, 34 -0.11 0.085 0.197 0.7047 0.896 0.759 1.06 -0.0854 0.223 0.702 0.1536 0.918 0.593 1.42 -0.328 0.238 0.167 0.7762 0.72 0.452 1.15 -0.255 0.233 0.273 0.5633 0.775 0.491 1.22 PRS_PLINK_1.99526231496888e.06 245.21 Chronic lymphocytic thyroiditis Both 145 1639 3 endocrine/metabolic brown 1639, 145 420, 41 400, 43 411, 30 408, 31 -0.109 0.0868 0.209 0.6798 0.897 0.756 1.06 0.0778 0.227 0.732 0.1354 1.08 0.692 1.69 -0.267 0.248 0.28 0.5526 0.765 0.471 1.24 -0.23 0.244 0.347 0.4596 0.795 0.492 1.28 PRS_PLINK_1.99526231496888e.06 246 Other disorders of thyroid Both 260 3014 3 endocrine/metabolic brown 3014, 260 758, 66 748, 65 754, 64 753, 65 0.0162 0.0646 0.802 0.09583 1.02 0.896 1.15 0.00273 0.181 0.988 0.005257 1 0.703 1.43 -0.0299 0.181 0.869 0.06096 0.971 0.681 1.38 0.0114 0.181 0.95 0.02246 1.01 0.71 1.44 PRS_PLINK_1.99526231496888e.06 250 Diabetes mellitus Both 10925 131077 3 endocrine/metabolic brown 131077, 10925 32836, 2708 32840, 2701 32677, 2705 32678, 2808 0.0175 0.00986 0.0758 1.12 1.02 0.998 1.04 -0.00462 0.0283 0.87 0.06038 0.995 0.942 1.05 -0.000776 0.0283 0.978 0.009609 0.999 0.945 1.06 0.0347 0.0281 0.217 0.663 1.04 0.98 1.09 PRS_PLINK_1.99526231496888e.06 250.1 Type 1 diabetes Both 1489 19737 3 endocrine/metabolic brown 19737, 1489 4957, 387 4921, 371 4949, 400 4906, 331 -0.0365 0.0269 0.175 0.7561 0.964 0.915 1.02 -0.0319 0.0753 0.672 0.1725 0.969 0.836 1.12 0.0394 0.0741 0.594 0.2259 1.04 0.9 1.2 -0.137 0.0776 0.0766 1.116 0.872 0.749 1.01 PRS_PLINK_1.99526231496888e.06 250.11 Type 1 diabetes with ketoacidosis Both 140 1800 3 endocrine/metabolic brown 1800, 140 452, 37 453, 41 447, 40 447, 22 -0.173 0.0921 0.0599 1.223 0.841 0.702 1.01 0.125 0.233 0.591 0.2287 1.13 0.718 1.79 0.1 0.234 0.669 0.1746 1.11 0.699 1.75 -0.531 0.272 0.051 1.292 0.588 0.345 1 PRS_PLINK_1.99526231496888e.06 250.12 Type 1 diabetes with renal manifestations Both 8 556 3 endocrine/metabolic brown 556, 8 142, 2 136, 2 139, 2 139, 2 -0.0302 0.288 0.916 0.03796 0.97 0.552 1.7 -0.0497 0.737 0.946 0.024 0.951 0.224 4.04 -0.381 0.766 0.619 0.2084 0.683 0.152 3.07 -0.093 0.748 0.901 0.04527 0.911 0.21 3.95 PRS_PLINK_1.99526231496888e.06 250.13 Type 1 diabetes with ophthalmic manifestations Both 222 3357 3 endocrine/metabolic brown 3357, 222 841, 62 840, 49 850, 66 826, 45 -0.0658 0.0692 0.342 0.4666 0.936 0.818 1.07 -0.238 0.195 0.221 0.6553 0.788 0.538 1.15 0.0641 0.182 0.724 0.14 1.07 0.746 1.52 -0.292 0.199 0.142 0.8466 0.746 0.505 1.1 PRS_PLINK_1.99526231496888e.06 250.14 Type 1 diabetes with neurological manifestations Both 51 1141 3 endocrine/metabolic brown 1141, 51 287, 13 284, 15 286, 14 284, 9 -0.152 0.143 0.286 0.5435 0.859 0.649 1.14 0.192 0.371 0.605 0.2184 1.21 0.586 2.51 0.0802 0.375 0.831 0.08052 1.08 0.519 2.26 -0.318 0.412 0.44 0.3563 0.728 0.325 1.63 PRS_PLINK_1.99526231496888e.06 250.2 Type 2 diabetes Both 9579 118577 3 endocrine/metabolic brown 118577, 9579 29752, 2389 29517, 2338 29704, 2382 29567, 2468 0.0182 0.0105 0.0836 1.078 1.02 0.998 1.04 -0.0157 0.0302 0.605 0.2184 0.984 0.928 1.04 -0.00517 0.0301 0.864 0.06365 0.995 0.938 1.06 0.0334 0.0299 0.264 0.578 1.03 0.975 1.1 PRS_PLINK_1.99526231496888e.06 250.21 Type 2 diabetes with ketoacidosis Both 61 768 3 endocrine/metabolic brown 768, 61 195, 20 191, 10 190, 12 192, 19 -0.0423 0.132 0.749 0.1258 0.959 0.74 1.24 -0.714 0.386 0.0641 1.193 0.49 0.23 1.04 -0.458 0.364 0.209 0.6802 0.633 0.31 1.29 -0.07 0.327 0.831 0.08061 0.932 0.491 1.77 PRS_PLINK_1.99526231496888e.06 250.22 Type 2 diabetes with renal manifestations Both 25 1338 3 endocrine/metabolic brown 1338, 25 338, 5 332, 5 336, 5 332, 10 0.187 0.18 0.301 0.5219 1.21 0.846 1.72 0.0407 0.538 0.94 0.02701 1.04 0.363 2.99 -0.104 0.547 0.85 0.07078 0.902 0.309 2.63 0.661 0.498 0.184 0.7349 1.94 0.73 5.14 PRS_PLINK_1.99526231496888e.06 250.23 Type 2 diabetes with ophthalmic manifestations Both 397 6711 3 endocrine/metabolic brown 6711, 397 1677, 99 1684, 101 1673, 94 1676, 103 0.0136 0.0509 0.789 0.1028 1.01 0.917 1.12 0.00329 0.145 0.982 0.007957 1 0.755 1.33 -0.0531 0.147 0.718 0.144 0.948 0.711 1.26 0.0256 0.144 0.859 0.06587 1.03 0.773 1.36 PRS_PLINK_1.99526231496888e.06 250.24 Type 2 diabetes with neurological manifestations Both 164 3447 3 endocrine/metabolic brown 3447, 164 862, 39 862, 44 863, 39 860, 42 0.0099 0.0783 0.899 0.04603 1.01 0.866 1.18 0.119 0.221 0.589 0.2297 1.13 0.731 1.74 -0.00578 0.227 0.98 0.008898 0.994 0.637 1.55 0.0621 0.223 0.781 0.1073 1.06 0.687 1.65 PRS_PLINK_1.99526231496888e.06 250.4 Abnormal glucose Both 400 4888 3 endocrine/metabolic brown 4888, 400 1226, 113 1213, 88 1227, 102 1216, 96 -0.0226 0.0523 0.666 0.1767 0.978 0.882 1.08 -0.238 0.147 0.105 0.9768 0.788 0.591 1.05 -0.101 0.142 0.475 0.323 0.904 0.685 1.19 -0.148 0.144 0.305 0.5157 0.863 0.651 1.14 PRS_PLINK_1.99526231496888e.06 250.41 Impaired fasting glucose Both 172 1858 3 endocrine/metabolic brown 1858, 172 470, 52 461, 29 462, 45 463, 46 -0.00446 0.0796 0.955 0.01988 0.996 0.852 1.16 -0.554 0.237 0.0196 1.709 0.574 0.361 0.915 -0.144 0.212 0.498 0.3028 0.866 0.572 1.31 -0.081 0.211 0.701 0.1544 0.922 0.61 1.39 PRS_PLINK_1.99526231496888e.06 250.42 Other abnormal glucose Both 228 3014 3 endocrine/metabolic brown 3014, 228 767, 62 736, 56 757, 57 750, 52 -0.0227 0.0693 0.743 0.1288 0.978 0.853 1.12 -0.0578 0.19 0.76 0.119 0.944 0.651 1.37 -0.0636 0.188 0.735 0.1335 0.938 0.649 1.36 -0.138 0.193 0.474 0.3242 0.871 0.597 1.27 PRS_PLINK_1.99526231496888e.06 250.5 Glycosuria or Acetonuria Both 104 1107 3 endocrine/metabolic brown 1107, 104 277, 25 279, 33 274, 21 277, 25 -0.0676 0.108 0.532 0.2738 0.935 0.756 1.16 0.263 0.273 0.336 0.4738 1.3 0.761 2.22 -0.157 0.299 0.6 0.2221 0.855 0.475 1.54 -0.028 0.288 0.923 0.03492 0.972 0.553 1.71 PRS_PLINK_1.99526231496888e.06 250.6 Polyneuropathy in diabetes Both 124 2404 3 endocrine/metabolic brown 2404, 124 601, 33 604, 35 600, 29 599, 27 -0.0936 0.0924 0.311 0.5072 0.911 0.76 1.09 0.0488 0.245 0.842 0.07469 1.05 0.65 1.7 -0.133 0.257 0.605 0.2181 0.876 0.529 1.45 -0.194 0.26 0.456 0.3409 0.824 0.495 1.37 PRS_PLINK_1.99526231496888e.06 250.7 Diabetic retinopathy Both 596 9087 3 endocrine/metabolic brown 9087, 596 2277, 152 2266, 147 2273, 152 2270, 145 -0.0185 0.0419 0.659 0.1814 0.982 0.904 1.07 -0.0326 0.119 0.784 0.1058 0.968 0.767 1.22 0.00932 0.118 0.937 0.02827 1.01 0.801 1.27 -0.0405 0.119 0.735 0.1339 0.96 0.76 1.21 PRS_PLINK_1.99526231496888e.06 251.1 Hypoglycemia Both 451 6676 3 endocrine/metabolic brown 6676, 451 1688, 121 1663, 123 1659, 117 1666, 90 -0.109 0.0495 0.0272 1.565 0.897 0.814 0.988 0.0366 0.132 0.782 0.107 1.04 0.801 1.34 -0.0086 0.134 0.949 0.02289 0.991 0.763 1.29 -0.27 0.143 0.0582 1.235 0.763 0.577 1.01 PRS_PLINK_1.99526231496888e.06 252 Disorders of parathyroid gland Both 461 6281 3 endocrine/metabolic brown 6281, 461 1591, 108 1552, 107 1573, 120 1564, 126 0.087 0.0473 0.0659 1.181 1.09 0.994 1.2 0.00363 0.14 0.979 0.009075 1 0.763 1.32 0.122 0.137 0.372 0.43 1.13 0.865 1.48 0.157 0.135 0.245 0.6113 1.17 0.898 1.53 PRS_PLINK_1.99526231496888e.06 252.1 Hyperparathyroidism Both 417 5639 3 endocrine/metabolic brown 5639, 417 1411, 95 1408, 106 1417, 106 1402, 110 0.0583 0.0503 0.246 0.6096 1.06 0.961 1.17 0.104 0.145 0.475 0.3231 1.11 0.834 1.47 0.108 0.145 0.456 0.3413 1.11 0.838 1.48 0.132 0.144 0.36 0.4441 1.14 0.86 1.51 PRS_PLINK_1.99526231496888e.06 252.2 Hypoparathyroidism Both 59 1003 3 endocrine/metabolic brown 1003, 59 255, 14 247, 11 251, 16 250, 18 0.228 0.124 0.0656 1.183 1.26 0.985 1.6 -0.26 0.391 0.506 0.296 0.771 0.358 1.66 0.162 0.362 0.655 0.1839 1.18 0.578 2.39 0.272 0.352 0.439 0.3571 1.31 0.659 2.62 PRS_PLINK_1.99526231496888e.06 253 Disorders of the pituitary gland and its hypothalamic control Both 413 4880 3 endocrine/metabolic brown 4880, 413 1225, 105 1217, 96 1239, 109 1197, 102 0.0166 0.0504 0.742 0.1297 1.02 0.921 1.12 -0.0868 0.146 0.553 0.2574 0.917 0.689 1.22 0.0168 0.142 0.905 0.04314 1.02 0.77 1.34 -0.00904 0.144 0.95 0.02228 0.991 0.747 1.31 PRS_PLINK_1.99526231496888e.06 253.1 Pituitary hyperfunction Both 122 1392 3 endocrine/metabolic brown 1392, 122 362, 32 335, 30 349, 25 346, 35 0.0432 0.0925 0.64 0.1936 1.04 0.871 1.25 0.0408 0.26 0.875 0.05779 1.04 0.626 1.73 -0.193 0.27 0.475 0.3233 0.825 0.486 1.4 0.139 0.252 0.581 0.2357 1.15 0.701 1.88 PRS_PLINK_1.99526231496888e.06 253.11 Acromegaly and gigantism Both 61 699 3 endocrine/metabolic brown 699, 61 175, 9 175, 14 174, 17 175, 21 0.264 0.124 0.0333 1.477 1.3 1.02 1.66 0.334 0.417 0.424 0.3731 1.4 0.616 3.16 0.66 0.404 0.102 0.9901 1.93 0.877 4.27 0.778 0.392 0.0474 1.324 2.18 1.01 4.7 PRS_PLINK_1.99526231496888e.06 253.2 Pituitary hypofunction Both 143 1869 3 endocrine/metabolic brown 1869, 143 475, 32 460, 37 466, 43 467, 31 -0.0128 0.0847 0.88 0.05553 0.987 0.836 1.17 0.153 0.245 0.533 0.2736 1.17 0.72 1.89 0.275 0.239 0.25 0.602 1.32 0.824 2.1 -0.0153 0.255 0.952 0.02123 0.985 0.597 1.62 PRS_PLINK_1.99526231496888e.06 253.3 Diabetes insipidus Both 47 715 3 endocrine/metabolic brown 715, 47 178, 16 179, 13 180, 16 177, 2 -0.457 0.17 0.00724 2.14 0.633 0.454 0.884 -0.258 0.376 0.493 0.3074 0.773 0.37 1.61 -0.0271 0.356 0.939 0.02719 0.973 0.485 1.95 -1.93 0.639 0.00256 2.591 0.145 0.0415 0.509 PRS_PLINK_1.99526231496888e.06 253.7 Other disorders of neurohypophysis Both 107 1033 3 endocrine/metabolic brown 1033, 107 263, 26 255, 23 257, 23 258, 34 0.0968 0.0953 0.31 0.5084 1.1 0.914 1.33 -0.0383 0.294 0.896 0.04759 0.962 0.541 1.71 -0.117 0.293 0.689 0.1618 0.889 0.501 1.58 0.304 0.274 0.267 0.5737 1.35 0.793 2.32 PRS_PLINK_1.99526231496888e.06 255 Disorders of adrenal glands Both 337 4714 3 endocrine/metabolic brown 4714, 337 1179, 87 1178, 95 1186, 74 1171, 81 -0.0402 0.0577 0.486 0.3129 0.961 0.858 1.08 0.0912 0.153 0.551 0.2587 1.1 0.812 1.48 -0.16 0.162 0.323 0.4906 0.852 0.621 1.17 -0.0596 0.159 0.707 0.1503 0.942 0.69 1.29 PRS_PLINK_1.99526231496888e.06 255.1 Adrenal hyperfunction Both 90 1352 3 endocrine/metabolic brown 1352, 90 338, 23 338, 21 339, 17 337, 29 0.117 0.107 0.275 0.5612 1.12 0.911 1.39 -0.12 0.303 0.692 0.1598 0.887 0.49 1.61 -0.306 0.319 0.336 0.4733 0.736 0.394 1.37 0.221 0.284 0.437 0.3591 1.25 0.715 2.18 PRS_PLINK_1.99526231496888e.06 255.11 Cushing's syndrome Both 52 805 3 endocrine/metabolic brown 805, 52 204, 14 200, 15 202, 6 199, 17 0.0791 0.139 0.57 0.2442 1.08 0.824 1.42 0.0891 0.367 0.808 0.09258 1.09 0.533 2.24 -0.837 0.461 0.0691 1.16 0.433 0.175 1.07 0.165 0.362 0.649 0.1877 1.18 0.58 2.4 PRS_PLINK_1.99526231496888e.06 255.12 Hyperaldosteronism Both 38 549 3 endocrine/metabolic brown 549, 38 140, 9 135, 7 137, 10 137, 12 0.164 0.167 0.326 0.4871 1.18 0.85 1.63 -0.428 0.492 0.384 0.4152 0.652 0.249 1.71 0.0276 0.448 0.951 0.02188 1.03 0.427 2.47 0.314 0.43 0.465 0.3329 1.37 0.59 3.18 PRS_PLINK_1.99526231496888e.06 255.2 Adrenal hypofunction Both 185 2651 3 endocrine/metabolic brown 2651, 185 672, 51 658, 47 663, 51 658, 36 -0.0614 0.0783 0.433 0.3638 0.94 0.807 1.1 -0.0527 0.207 0.799 0.09762 0.949 0.633 1.42 0.0479 0.203 0.814 0.0896 1.05 0.704 1.56 -0.333 0.221 0.132 0.8802 0.717 0.465 1.11 PRS_PLINK_1.99526231496888e.06 255.21 Glucocorticoid deficiency Both 185 2645 3 endocrine/metabolic brown 2645, 185 672, 51 655, 47 662, 51 656, 36 -0.06 0.0782 0.443 0.3538 0.942 0.808 1.1 -0.048 0.207 0.816 0.08815 0.953 0.636 1.43 0.0502 0.203 0.805 0.09427 1.05 0.706 1.57 -0.33 0.221 0.135 0.8687 0.719 0.466 1.11 PRS_PLINK_1.99526231496888e.06 256 Ovarian dysfunction Female 204 2141 3 endocrine/metabolic brown 2141, 204 554, 55 524, 44 530, 51 533, 53 0.0272 0.0752 0.718 0.144 1.03 0.887 1.19 -0.158 0.209 0.452 0.3451 0.854 0.567 1.29 -0.042 0.202 0.835 0.07821 0.959 0.646 1.42 -0.00742 0.2 0.97 0.01306 0.993 0.671 1.47 PRS_PLINK_1.99526231496888e.06 256.4 Polycystic ovaries Female 174 1876 3 endocrine/metabolic brown 1876, 174 469, 46 469, 44 472, 38 466, 45 -0.00384 0.0812 0.962 0.01668 0.996 0.85 1.17 -0.0397 0.218 0.856 0.06769 0.961 0.627 1.47 -0.2 0.225 0.374 0.4268 0.819 0.527 1.27 -0.0186 0.217 0.931 0.03083 0.982 0.642 1.5 PRS_PLINK_1.99526231496888e.06 257 Testicular dysfunction Male 87 1131 3 endocrine/metabolic brown 1131, 87 283, 28 283, 19 287, 14 278, 26 0.0057 0.108 0.958 0.01867 1.01 0.814 1.24 -0.378 0.3 0.207 0.6833 0.685 0.38 1.23 -0.694 0.327 0.034 1.468 0.5 0.263 0.949 -0.0357 0.279 0.898 0.0466 0.965 0.558 1.67 PRS_PLINK_1.99526231496888e.06 257.1 Testicular hypofunction Male 80 1064 3 endocrine/metabolic brown 1064, 80 267, 26 266, 18 267, 12 264, 24 0.0106 0.113 0.926 0.03349 1.01 0.809 1.26 -0.363 0.31 0.241 0.6185 0.695 0.379 1.28 -0.738 0.347 0.0334 1.476 0.478 0.242 0.944 -0.0543 0.29 0.852 0.0698 0.947 0.537 1.67 PRS_PLINK_1.99526231496888e.06 258 Iatrogenic endocrine disorders Both 55 752 3 endocrine/metabolic brown 752, 55 188, 14 188, 16 188, 11 188, 14 -0.0573 0.134 0.67 0.1741 0.944 0.726 1.23 0.0696 0.369 0.85 0.07048 1.07 0.52 2.21 -0.24 0.397 0.544 0.2641 0.786 0.361 1.71 0.0235 0.375 0.95 0.02226 1.02 0.491 2.14 PRS_PLINK_1.99526231496888e.06 259 Other endocrine disorders Both 102 1134 3 endocrine/metabolic brown 1134, 102 289, 30 281, 25 283, 24 281, 23 -0.0989 0.107 0.355 0.4502 0.906 0.735 1.12 -0.172 0.278 0.537 0.27 0.842 0.489 1.45 -0.255 0.281 0.364 0.4385 0.775 0.446 1.34 -0.256 0.282 0.365 0.4376 0.774 0.445 1.35 PRS_PLINK_1.99526231496888e.06 260 Protein-calorie malnutrition Both 117 1414 3 endocrine/metabolic brown 1414, 117 357, 36 352, 28 353, 28 351, 25 -0.137 0.0958 0.153 0.8157 0.872 0.723 1.05 -0.225 0.26 0.387 0.4128 0.798 0.48 1.33 -0.225 0.257 0.383 0.4172 0.799 0.482 1.32 -0.34 0.266 0.202 0.695 0.712 0.423 1.2 PRS_PLINK_1.99526231496888e.06 260.1 Cachexia Both 27 340 3 endocrine/metabolic brown 340, 27 85, 8 85, 6 85, 8 85, 5 -0.0154 0.192 0.936 0.02873 0.985 0.676 1.44 -0.357 0.52 0.492 0.3076 0.7 0.252 1.94 -0.135 0.497 0.787 0.1042 0.874 0.33 2.32 -0.32 0.543 0.555 0.2555 0.726 0.251 2.1 PRS_PLINK_1.99526231496888e.06 260.6 Anorexia Both 494 5856 3 endocrine/metabolic brown 5856, 494 1462, 126 1464, 141 1483, 112 1445, 114 -0.0428 0.0463 0.355 0.4495 0.958 0.875 1.05 0.122 0.128 0.34 0.4683 1.13 0.88 1.45 -0.119 0.134 0.376 0.4248 0.888 0.682 1.16 -0.0897 0.134 0.504 0.298 0.914 0.703 1.19 PRS_PLINK_1.99526231496888e.06 261 Vitamin deficiency Both 692 8706 3 endocrine/metabolic brown 8706, 692 2184, 177 2166, 161 2201, 181 2152, 173 0.011 0.0392 0.778 0.1088 1.01 0.936 1.09 -0.0827 0.113 0.462 0.3349 0.921 0.738 1.15 0.0347 0.11 0.752 0.1237 1.04 0.835 1.28 -0.000847 0.111 0.994 0.002654 0.999 0.804 1.24 PRS_PLINK_1.99526231496888e.06 261.2 Vitamin B-complex deficiencies Both 440 5454 3 endocrine/metabolic brown 5454, 440 1361, 116 1364, 95 1367, 119 1359, 110 0.0184 0.0492 0.709 0.1494 1.02 0.925 1.12 -0.205 0.143 0.151 0.8208 0.815 0.616 1.08 0.0353 0.135 0.794 0.09991 1.04 0.795 1.35 -0.0553 0.138 0.689 0.162 0.946 0.722 1.24 PRS_PLINK_1.99526231496888e.06 261.4 Vitamin D deficiency Both 258 3312 3 endocrine/metabolic brown 3312, 258 831, 59 831, 64 821, 68 828, 67 0.0304 0.0635 0.632 0.1991 1.03 0.91 1.17 0.0863 0.185 0.64 0.1936 1.09 0.759 1.57 0.173 0.183 0.345 0.4625 1.19 0.831 1.7 0.139 0.183 0.45 0.347 1.15 0.802 1.65 PRS_PLINK_1.99526231496888e.06 261.41 Rickets or osteomalacia Both 36 575 3 endocrine/metabolic brown 575, 36 145, 8 143, 9 144, 10 143, 9 0.00371 0.164 0.982 0.007915 1 0.728 1.38 0.113 0.463 0.807 0.09328 1.12 0.452 2.78 0.337 0.466 0.469 0.3289 1.4 0.562 3.49 0.138 0.463 0.766 0.1159 1.15 0.463 2.85 PRS_PLINK_1.99526231496888e.06 262 Mineral deficiency NEC Both 152 1775 3 endocrine/metabolic brown 1775, 152 461, 55 427, 27 447, 30 439, 40 -0.114 0.0867 0.19 0.7204 0.893 0.753 1.06 -0.598 0.24 0.0128 1.893 0.55 0.343 0.881 -0.563 0.233 0.0157 1.803 0.569 0.36 0.899 -0.258 0.217 0.235 0.6285 0.773 0.505 1.18 PRS_PLINK_1.99526231496888e.06 269 Proteinuria Both 158 2372 3 endocrine/metabolic brown 2372, 158 593, 32 593, 43 605, 47 581, 36 0.053 0.0824 0.52 0.2838 1.05 0.897 1.24 0.272 0.237 0.249 0.603 1.31 0.826 2.09 0.361 0.233 0.122 0.9153 1.43 0.909 2.26 0.15 0.247 0.543 0.265 1.16 0.716 1.89 PRS_PLINK_1.99526231496888e.06 270 Disorders of protein plasma/amino-acid transport and metabolism Both 160 2051 3 endocrine/metabolic brown 2051, 160 519, 32 507, 44 516, 42 509, 42 0.0867 0.0761 0.255 0.5939 1.09 0.939 1.27 0.327 0.236 0.166 0.7795 1.39 0.873 2.2 0.274 0.239 0.252 0.5995 1.32 0.823 2.1 0.293 0.238 0.218 0.6617 1.34 0.841 2.14 PRS_PLINK_1.99526231496888e.06 270.3 Disorders of plasma protein metabolism Both 134 1749 3 endocrine/metabolic brown 1749, 134 450, 29 425, 34 437, 34 437, 37 0.112 0.0833 0.18 0.744 1.12 0.95 1.32 0.21 0.256 0.412 0.385 1.23 0.747 2.04 0.167 0.258 0.517 0.2862 1.18 0.713 1.96 0.287 0.252 0.256 0.5923 1.33 0.812 2.18 PRS_PLINK_1.99526231496888e.06 270.32 Paraproteinemia Both 94 1263 3 endocrine/metabolic brown 1263, 94 322, 20 312, 20 318, 29 311, 25 0.136 0.0961 0.156 0.8073 1.15 0.949 1.38 0.0328 0.314 0.917 0.03772 1.03 0.558 1.91 0.355 0.294 0.227 0.6445 1.43 0.802 2.54 0.275 0.302 0.362 0.4414 1.32 0.729 2.38 PRS_PLINK_1.99526231496888e.06 270.33 Amyloidosis Both 55 764 3 endocrine/metabolic brown 764, 55 190, 11 191, 18 191, 8 191, 18 0.00373 0.134 0.978 0.009758 1 0.772 1.3 0.46 0.382 0.228 0.6412 1.58 0.749 3.35 -0.414 0.444 0.351 0.4542 0.661 0.277 1.58 0.472 0.379 0.212 0.673 1.6 0.764 3.37 PRS_PLINK_1.99526231496888e.06 270.35 Macroglobulinemia Both 36 475 3 endocrine/metabolic brown 475, 36 119, 8 120, 10 117, 9 119, 9 -0.013 0.168 0.938 0.02769 0.987 0.711 1.37 0.135 0.472 0.775 0.1106 1.14 0.454 2.89 -0.0115 0.474 0.981 0.008525 0.989 0.391 2.5 0.0899 0.473 0.849 0.07097 1.09 0.433 2.77 PRS_PLINK_1.99526231496888e.06 271 Disorders of carbohydrate transport and metabolism Both 109 1184 3 endocrine/metabolic brown 1184, 109 296, 23 297, 18 299, 41 292, 27 0.106 0.0985 0.281 0.5518 1.11 0.917 1.35 -0.231 0.317 0.467 0.3311 0.794 0.426 1.48 0.58 0.268 0.0305 1.516 1.79 1.06 3.02 0.156 0.288 0.589 0.2301 1.17 0.665 2.05 PRS_PLINK_1.99526231496888e.06 271.3 Intestinal disaccharidase deficiencies and disaccharide malabsorption Both 99 1039 3 endocrine/metabolic brown 1039, 99 263, 21 256, 18 261, 36 258, 24 0.0775 0.105 0.459 0.3385 1.08 0.88 1.33 -0.126 0.325 0.699 0.1558 0.882 0.466 1.67 0.532 0.281 0.0585 1.233 1.7 0.981 2.95 0.132 0.303 0.663 0.1786 1.14 0.63 2.07 PRS_PLINK_1.99526231496888e.06 272 Disorders of lipoid metabolism Both 20417 170572 3 endocrine/metabolic brown 170572, 20417 42795, 5078 42440, 4934 42688, 5074 42598, 5321 0.00864 0.00738 0.242 0.616 1.01 0.994 1.02 -0.026 0.0213 0.222 0.6532 0.974 0.935 1.02 -0.0199 0.0211 0.346 0.4607 0.98 0.94 1.02 0.0152 0.0209 0.468 0.3297 1.02 0.974 1.06 PRS_PLINK_1.99526231496888e.06 272.1 Hyperlipidemia Both 20374 170389 3 endocrine/metabolic brown 170389, 20374 42757, 5069 42387, 4920 42638, 5065 42556, 5310 0.0084 0.00739 0.256 0.592 1.01 0.994 1.02 -0.0266 0.0213 0.211 0.6752 0.974 0.934 1.02 -0.0198 0.0212 0.35 0.4562 0.98 0.941 1.02 0.0151 0.021 0.472 0.3259 1.02 0.974 1.06 PRS_PLINK_1.99526231496888e.06 272.11 Hypercholesterolemia Both 18889 164486 3 endocrine/metabolic brown 164486, 18889 41242, 4692 41288, 4609 40965, 4660 40941, 4919 0.011 0.00764 0.151 0.8202 1.01 0.996 1.03 -0.0244 0.022 0.267 0.5743 0.976 0.935 1.02 -0.02 0.022 0.362 0.4413 0.98 0.939 1.02 0.0217 0.0217 0.318 0.4975 1.02 0.979 1.07 PRS_PLINK_1.99526231496888e.06 272.12 Hyperglyceridemia Both 38 411 3 endocrine/metabolic brown 411, 38 103, 10 103, 10 102, 8 103, 10 -0.0294 0.165 0.859 0.0661 0.971 0.702 1.34 -0.0627 0.46 0.891 0.0499 0.939 0.381 2.31 -0.143 0.472 0.761 0.1185 0.866 0.344 2.18 PRS_PLINK_1.99526231496888e.06 272.13 Mixed hyperlipidemia Both 84 1154 3 endocrine/metabolic brown 1154, 84 290, 18 287, 26 289, 19 288, 21 0.0504 0.11 0.647 0.1893 1.05 0.848 1.3 0.373 0.31 0.229 0.641 1.45 0.791 2.67 0.11 0.329 0.738 0.1321 1.12 0.586 2.13 0.155 0.325 0.632 0.1993 1.17 0.618 2.21 PRS_PLINK_1.99526231496888e.06 272.9 Unspecified disorder of lipoid metabolism Both 118 1442 3 endocrine/metabolic brown 1442, 118 364, 28 356, 28 359, 25 361, 37 0.167 0.0901 0.064 1.194 1.18 0.99 1.41 0.0361 0.271 0.894 0.0486 1.04 0.61 1.76 -0.109 0.277 0.695 0.1578 0.897 0.521 1.54 0.312 0.257 0.225 0.6484 1.37 0.825 2.26 PRS_PLINK_1.99526231496888e.06 274 Gout and other crystal arthropathies Both 1596 24798 3 endocrine/metabolic brown 24798, 1596 6190, 378 6242, 374 6163, 405 6189, 437 0.0576 0.0253 0.023 1.639 1.06 1.01 1.11 -0.0213 0.075 0.777 0.1096 0.979 0.845 1.13 0.076 0.0737 0.302 0.5197 1.08 0.934 1.25 0.155 0.0725 0.0326 1.487 1.17 1.01 1.35 PRS_PLINK_1.99526231496888e.06 274.1 Gout Both 1237 20817 3 endocrine/metabolic brown 20817, 1237 5238, 294 5174, 286 5197, 326 5202, 329 0.0484 0.0287 0.0914 1.039 1.05 0.992 1.11 -0.0142 0.0852 0.867 0.06182 0.986 0.834 1.17 0.113 0.0827 0.171 0.7679 1.12 0.952 1.32 0.128 0.0826 0.122 0.9136 1.14 0.966 1.34 PRS_PLINK_1.99526231496888e.06 274.11 Gouty arthropathy Both 51 735 3 endocrine/metabolic brown 735, 51 188, 12 182, 11 182, 14 183, 14 0.071 0.139 0.609 0.215 1.07 0.818 1.41 -0.119 0.413 0.773 0.112 0.887 0.395 2 0.188 0.39 0.63 0.2006 1.21 0.562 2.59 0.158 0.389 0.685 0.1644 1.17 0.546 2.51 PRS_PLINK_1.99526231496888e.06 274.2 Crystal arthropathies Both 384 4360 3 endocrine/metabolic brown 4360, 384 1082, 91 1091, 84 1090, 88 1089, 121 0.107 0.0523 0.0414 1.383 1.11 1 1.23 -0.0865 0.156 0.58 0.2367 0.917 0.675 1.25 -0.0529 0.154 0.732 0.1356 0.948 0.701 1.28 0.267 0.145 0.0648 1.188 1.31 0.984 1.73 PRS_PLINK_1.99526231496888e.06 274.21 Chondrocalcinosis Both 356 3988 3 endocrine/metabolic brown 3988, 356 992, 83 997, 80 1000, 80 992, 113 0.114 0.054 0.0344 1.463 1.12 1.01 1.25 -0.0431 0.162 0.79 0.1025 0.958 0.698 1.31 -0.0574 0.162 0.723 0.1411 0.944 0.688 1.3 0.294 0.151 0.0508 1.294 1.34 0.999 1.8 PRS_PLINK_1.99526231496888e.06 275 Disorders of mineral metabolism Both 1172 14742 3 endocrine/metabolic brown 14742, 1172 3690, 250 3687, 311 3680, 299 3679, 312 0.09 0.0297 0.00241 2.617 1.09 1.03 1.16 0.221 0.0879 0.0118 1.927 1.25 1.05 1.48 0.185 0.0886 0.0368 1.434 1.2 1.01 1.43 0.233 0.0879 0.00812 2.091 1.26 1.06 1.5 PRS_PLINK_1.99526231496888e.06 275.1 Disorders of iron metabolism Both 423 4588 4 hematopoietic darkorange1 4588, 423 1153, 89 1142, 121 1148, 105 1144, 108 0.0722 0.0497 0.146 0.8353 1.07 0.975 1.18 0.316 0.145 0.0291 1.537 1.37 1.03 1.82 0.177 0.149 0.236 0.6271 1.19 0.891 1.6 0.205 0.148 0.166 0.7787 1.23 0.918 1.64 PRS_PLINK_1.99526231496888e.06 275.3 Disorders of magnesium metabolism Both 200 2573 3 endocrine/metabolic brown 2573, 200 656, 38 630, 49 645, 59 641, 54 0.148 0.0706 0.0359 1.444 1.16 1.01 1.33 0.283 0.22 0.198 0.7025 1.33 0.862 2.04 0.455 0.212 0.0321 1.494 1.58 1.04 2.39 0.384 0.216 0.0753 1.123 1.47 0.962 2.24 PRS_PLINK_1.99526231496888e.06 275.5 Disorders of calcium/phosphorus metabolism Both 610 8470 3 endocrine/metabolic brown 8470, 610 2114, 135 2122, 148 2139, 160 2091, 167 0.0993 0.0408 0.0149 1.828 1.1 1.02 1.2 0.0858 0.122 0.483 0.3161 1.09 0.857 1.38 0.158 0.12 0.189 0.7238 1.17 0.925 1.48 0.233 0.119 0.0513 1.29 1.26 0.999 1.59 PRS_PLINK_1.99526231496888e.06 275.53 Disorders of phosphorus metabolism Both 100 1209 3 endocrine/metabolic brown 1209, 100 303, 28 304, 20 304, 24 298, 28 0.0461 0.103 0.656 0.1832 1.05 0.855 1.28 -0.337 0.294 0.252 0.5981 0.714 0.401 1.27 -0.137 0.284 0.628 0.2018 0.872 0.5 1.52 -0.0397 0.275 0.885 0.05299 0.961 0.561 1.65 PRS_PLINK_1.99526231496888e.06 276 Disorders of fluid, electrolyte, and acid-base balance Both 3665 50343 3 endocrine/metabolic brown 50343, 3665 12657, 911 12532, 860 12590, 940 12547, 952 0.0311 0.0168 0.0646 1.19 1.03 0.998 1.07 -0.0468 0.0492 0.341 0.4674 0.954 0.867 1.05 0.0371 0.0482 0.441 0.3558 1.04 0.944 1.14 0.0567 0.0481 0.239 0.6222 1.06 0.963 1.16 PRS_PLINK_1.99526231496888e.06 276.1 Electrolyte imbalance Both 2110 28095 3 endocrine/metabolic brown 28095, 2110 7020, 504 7068, 495 6984, 538 7013, 571 0.0539 0.0222 0.0151 1.822 1.06 1.01 1.1 -0.0249 0.0654 0.704 0.1525 0.975 0.858 1.11 0.0689 0.0642 0.283 0.5478 1.07 0.945 1.21 0.128 0.0634 0.044 1.357 1.14 1 1.29 PRS_PLINK_1.99526231496888e.06 276.11 Hyperosmolality and/or hypernatremia Both 121 1585 3 endocrine/metabolic brown 1585, 121 399, 26 396, 29 394, 28 396, 38 0.143 0.0888 0.106 0.9728 1.15 0.97 1.37 0.103 0.272 0.705 0.1518 1.11 0.651 1.89 0.0957 0.274 0.726 0.1389 1.1 0.644 1.88 0.405 0.26 0.119 0.9243 1.5 0.901 2.5 PRS_PLINK_1.99526231496888e.06 276.12 Hyposmolality and/or hyponatremia Both 1071 12445 3 endocrine/metabolic brown 12445, 1071 3119, 263 3107, 255 3106, 273 3107, 278 0.0243 0.0315 0.44 0.3569 1.02 0.963 1.09 -0.0293 0.0913 0.748 0.1259 0.971 0.812 1.16 0.0376 0.0899 0.676 0.1699 1.04 0.871 1.24 0.0548 0.0896 0.541 0.267 1.06 0.886 1.26 PRS_PLINK_1.99526231496888e.06 276.13 Hyperpotassemia Both 311 6533 3 endocrine/metabolic brown 6533, 311 1639, 71 1626, 71 1656, 80 1608, 89 0.107 0.0568 0.0583 1.234 1.11 0.996 1.24 0.0123 0.17 0.942 0.02592 1.01 0.726 1.41 0.113 0.165 0.494 0.3063 1.12 0.81 1.55 0.242 0.162 0.135 0.8682 1.27 0.927 1.75 PRS_PLINK_1.99526231496888e.06 276.14 Hypopotassemia Both 773 10104 3 endocrine/metabolic brown 10104, 773 2526, 172 2534, 179 2526, 215 2516, 207 0.0744 0.0365 0.0415 1.382 1.08 1 1.16 0.0377 0.11 0.732 0.1356 1.04 0.837 1.29 0.224 0.106 0.0343 1.464 1.25 1.02 1.54 0.198 0.107 0.0632 1.199 1.22 0.989 1.5 PRS_PLINK_1.99526231496888e.06 276.4 Acid-base balance disorder Both 470 7952 3 endocrine/metabolic brown 7952, 470 1987, 123 1987, 125 1988, 101 1987, 121 -0.0199 0.0472 0.674 0.1715 0.98 0.894 1.08 0.0235 0.13 0.857 0.06724 1.02 0.793 1.32 -0.194 0.137 0.157 0.8043 0.824 0.63 1.08 -0.016 0.131 0.903 0.04431 0.984 0.761 1.27 PRS_PLINK_1.99526231496888e.06 276.41 Acidosis Both 420 7243 3 endocrine/metabolic brown 7243, 420 1813, 103 1811, 109 1809, 95 1807, 113 0.0206 0.0492 0.675 0.1704 1.02 0.927 1.12 0.0675 0.14 0.631 0.2 1.07 0.812 1.41 -0.0766 0.145 0.597 0.2239 0.926 0.697 1.23 0.101 0.139 0.467 0.3307 1.11 0.842 1.45 PRS_PLINK_1.99526231496888e.06 276.42 Alkalosis Both 52 746 3 endocrine/metabolic brown 746, 52 190, 22 181, 13 188, 7 185, 10 -0.316 0.154 0.0404 1.394 0.729 0.539 0.986 -0.405 0.355 0.254 0.5953 0.667 0.333 1.34 -1.07 0.422 0.0109 1.962 0.342 0.15 0.781 -0.705 0.378 0.0621 1.207 0.494 0.236 1.04 PRS_PLINK_1.99526231496888e.06 276.5 Hypovolemia Both 1409 19646 3 endocrine/metabolic brown 19646, 1409 4923, 360 4920, 341 4899, 351 4897, 357 0.00854 0.0272 0.754 0.1229 1.01 0.956 1.06 -0.0503 0.0781 0.52 0.2844 0.951 0.816 1.11 -0.0149 0.0776 0.848 0.0716 0.985 0.846 1.15 0.00432 0.0774 0.955 0.01979 1 0.863 1.17 PRS_PLINK_1.99526231496888e.06 276.6 Fluid overload Both 151 3022 3 endocrine/metabolic brown 3022, 151 761, 28 758, 35 749, 41 754, 47 0.214 0.0775 0.00572 2.243 1.24 1.06 1.44 0.238 0.252 0.345 0.4622 1.27 0.775 2.08 0.4 0.244 0.102 0.9911 1.49 0.924 2.41 0.51 0.239 0.0327 1.486 1.67 1.04 2.66 PRS_PLINK_1.99526231496888e.06 276.8 Polydipsia Both 88 971 3 endocrine/metabolic brown 971, 88 250, 23 236, 24 242, 26 243, 15 -0.088 0.112 0.43 0.366 0.916 0.736 1.14 0.12 0.299 0.689 0.1615 1.13 0.627 2.03 0.165 0.293 0.574 0.2411 1.18 0.664 2.09 -0.365 0.332 0.272 0.5659 0.694 0.362 1.33 PRS_PLINK_1.99526231496888e.06 277 Other disorders of metabolism Both 517 6497 3 endocrine/metabolic brown 6497, 517 1626, 115 1618, 136 1624, 131 1623, 135 0.053 0.0446 0.235 0.6291 1.05 0.966 1.15 0.171 0.131 0.191 0.7189 1.19 0.918 1.53 0.139 0.132 0.294 0.5323 1.15 0.887 1.49 0.175 0.131 0.181 0.7413 1.19 0.921 1.54 PRS_PLINK_1.99526231496888e.06 277.4 Disorders of bilirubin excretion Both 238 2573 3 endocrine/metabolic brown 2573, 238 647, 61 642, 57 660, 67 623, 52 -0.0316 0.0663 0.634 0.1982 0.969 0.851 1.1 -0.0855 0.191 0.655 0.1841 0.918 0.631 1.33 0.064 0.184 0.728 0.1378 1.07 0.743 1.53 -0.101 0.196 0.604 0.2187 0.904 0.616 1.33 PRS_PLINK_1.99526231496888e.06 277.5 Other disorders of lipoid metabolism Both 132 1611 3 endocrine/metabolic brown 1611, 132 416, 40 392, 28 408, 30 395, 34 0.0088 0.0902 0.922 0.03514 1.01 0.845 1.2 -0.268 0.253 0.289 0.5389 0.765 0.466 1.26 -0.277 0.248 0.264 0.5788 0.758 0.466 1.23 -0.106 0.241 0.66 0.1806 0.899 0.561 1.44 PRS_PLINK_1.99526231496888e.06 277.51 Lipoprotein disorders Both 26 367 3 endocrine/metabolic brown 367, 26 92, 8 92, 5 91, 5 92, 8 0.149 0.195 0.444 0.3522 1.16 0.792 1.7 -0.306 0.549 0.577 0.2385 0.737 0.251 2.16 -0.453 0.533 0.396 0.4026 0.636 0.224 1.81 -0.0696 0.492 0.887 0.05185 0.933 0.356 2.45 PRS_PLINK_1.99526231496888e.06 278 Overweight, obesity and other hyperalimentation Both 5600 79880 3 endocrine/metabolic brown 79880, 5600 19996, 1308 19946, 1295 20137, 1416 19779, 1580 0.087 0.0135 1.2e-10 9.922 1.09 1.06 1.12 -0.00527 0.0405 0.896 0.04748 0.995 0.919 1.08 0.0747 0.0396 0.0594 1.226 1.08 0.997 1.16 0.209 0.0388 6.92e-08 7.16 1.23 1.14 1.33 PRS_PLINK_1.99526231496888e.06 278.1 Obesity Both 5501 78655 3 endocrine/metabolic brown 78655, 5501 19712, 1282 19622, 1271 19843, 1393 19455, 1554 0.0886 0.0136 7.92e-11 10.1 1.09 1.06 1.12 -0.00179 0.0408 0.965 0.01547 0.998 0.921 1.08 0.0784 0.04 0.0499 1.302 1.08 1 1.17 0.215 0.0391 4.13e-08 7.384 1.24 1.15 1.34 PRS_PLINK_1.99526231496888e.06 278.3 Localized adiposity Both 61 686 3 endocrine/metabolic brown 686, 61 179, 18 164, 14 171, 15 172, 14 -0.00494 0.127 0.969 0.01372 0.995 0.776 1.28 -0.0731 0.362 0.84 0.07562 0.93 0.457 1.89 -0.159 0.355 0.655 0.1839 0.853 0.425 1.71 -0.177 0.358 0.621 0.2067 0.838 0.416 1.69 PRS_PLINK_1.99526231496888e.06 278.4 Abnormal weight gain Both 32 510 3 endocrine/metabolic brown 510, 32 135, 6 120, 8 129, 7 126, 11 0.159 0.166 0.34 0.468 1.17 0.846 1.62 0.482 0.514 0.349 0.4569 1.62 0.591 4.44 0.242 0.547 0.658 0.1818 1.27 0.436 3.73 0.701 0.481 0.145 0.8401 2.02 0.786 5.17 PRS_PLINK_1.99526231496888e.06 279 Disorders involving the immune mechanism Both 144 1853 3 endocrine/metabolic brown 1853, 144 469, 30 466, 39 456, 36 462, 39 0.0633 0.0843 0.453 0.3442 1.07 0.903 1.26 0.243 0.246 0.323 0.4904 1.28 0.787 2.07 0.206 0.251 0.411 0.3863 1.23 0.752 2.01 0.307 0.248 0.216 0.6663 1.36 0.836 2.21 PRS_PLINK_1.99526231496888e.06 279.1 Immunity deficiency Both 121 1545 3 endocrine/metabolic brown 1545, 121 388, 28 386, 29 390, 32 381, 32 0.0427 0.0913 0.64 0.194 1.04 0.873 1.25 0.00987 0.269 0.971 0.0129 1.01 0.596 1.71 0.0989 0.264 0.707 0.1503 1.1 0.659 1.85 0.179 0.265 0.499 0.3022 1.2 0.712 2.01 PRS_PLINK_1.99526231496888e.06 279.11 Deficiency of humoral immunity Both 77 1012 3 endocrine/metabolic brown 1012, 77 253, 21 253, 15 255, 20 251, 21 0.0622 0.117 0.594 0.2264 1.06 0.847 1.34 -0.324 0.34 0.341 0.4669 0.723 0.371 1.41 -0.0691 0.316 0.827 0.08241 0.933 0.502 1.73 0.122 0.318 0.702 0.1538 1.13 0.605 2.11 PRS_PLINK_1.99526231496888e.06 279.7 Other immunological findings Both 164 1594 3 endocrine/metabolic brown 1594, 164 401, 41 395, 31 398, 60 399, 32 0.0219 0.0811 0.787 0.1038 1.02 0.872 1.2 -0.278 0.245 0.256 0.5912 0.757 0.468 1.22 0.38 0.212 0.0735 1.133 1.46 0.964 2.22 -0.229 0.242 0.345 0.4625 0.795 0.495 1.28 PRS_PLINK_1.99526231496888e.06 280 Iron deficiency anemias Both 4717 56023 4 hematopoietic darkorange1 56023, 4717 14000, 1210 14094, 1124 14044, 1148 13869, 1234 0.0201 0.0151 0.183 0.7377 1.02 0.991 1.05 -0.0766 0.0431 0.0758 1.12 0.926 0.851 1.01 -0.0507 0.0429 0.237 0.6247 0.951 0.874 1.03 0.0388 0.0423 0.359 0.445 1.04 0.957 1.13 PRS_PLINK_1.99526231496888e.06 280.1 Iron deficiency anemias, unspecified or not due to blood loss Both 4497 53665 4 hematopoietic darkorange1 53665, 4497 13430, 1164 13444, 1061 13411, 1091 13365, 1180 0.0182 0.0154 0.239 0.6211 1.02 0.988 1.05 -0.0908 0.0442 0.0397 1.401 0.913 0.837 0.996 -0.059 0.0439 0.178 0.7485 0.943 0.865 1.03 0.0276 0.0432 0.523 0.2816 1.03 0.945 1.12 PRS_PLINK_1.99526231496888e.06 280.2 Iron deficiency anemia secondary to blood loss (chronic) Both 322 3555 4 hematopoietic darkorange1 3555, 322 888, 79 888, 83 889, 82 888, 78 -0.01 0.0586 0.864 0.06343 0.99 0.883 1.11 0.095 0.164 0.562 0.2505 1.1 0.798 1.52 0.0623 0.164 0.704 0.1525 1.06 0.772 1.47 0.000152 0.166 0.999 0.0003176 1 0.723 1.38 PRS_PLINK_1.99526231496888e.06 281 Other deficiency anemia Both 613 8034 4 hematopoietic darkorange1 8034, 613 2013, 137 2016, 160 2019, 151 1985, 164 0.0555 0.0414 0.18 0.7451 1.06 0.975 1.15 0.152 0.12 0.207 0.6848 1.16 0.92 1.47 0.101 0.122 0.406 0.3912 1.11 0.872 1.4 0.196 0.12 0.101 0.9945 1.22 0.962 1.54 PRS_PLINK_1.99526231496888e.06 281.1 Megaloblastic anemia Both 593 7703 4 hematopoietic darkorange1 7703, 593 1932, 132 1938, 157 1938, 147 1894, 156 0.0536 0.0421 0.203 0.6922 1.06 0.971 1.15 0.168 0.122 0.169 0.7724 1.18 0.931 1.5 0.112 0.124 0.366 0.4359 1.12 0.878 1.42 0.191 0.122 0.118 0.9275 1.21 0.953 1.54 PRS_PLINK_1.99526231496888e.06 281.11 Pernicious anemia Both 430 5434 4 hematopoietic darkorange1 5434, 430 1358, 106 1360, 111 1386, 98 1329, 115 0.0422 0.0496 0.395 0.4035 1.04 0.947 1.15 0.0388 0.14 0.782 0.1067 1.04 0.79 1.37 -0.094 0.144 0.515 0.2883 0.91 0.686 1.21 0.111 0.14 0.428 0.3683 1.12 0.85 1.47 PRS_PLINK_1.99526231496888e.06 281.12 Other vitamin B12 deficiency anemia Both 103 1327 4 hematopoietic darkorange1 1327, 103 339, 18 327, 24 329, 29 331, 31 0.161 0.0995 0.107 0.9726 1.17 0.966 1.43 0.3 0.31 0.333 0.477 1.35 0.735 2.48 0.523 0.303 0.0841 1.075 1.69 0.932 3.05 0.591 0.299 0.048 1.319 1.81 1.01 3.24 PRS_PLINK_1.99526231496888e.06 281.13 Folate-deficiency anemia Both 80 1277 4 hematopoietic darkorange1 1277, 80 329, 13 311, 23 321, 24 316, 20 0.0262 0.112 0.815 0.08888 1.03 0.824 1.28 0.625 0.34 0.0661 1.18 1.87 0.959 3.64 0.631 0.339 0.0622 1.206 1.88 0.968 3.65 0.457 0.348 0.189 0.7231 1.58 0.798 3.12 PRS_PLINK_1.99526231496888e.06 281.9 Deficiency anemias Both 23 369 4 hematopoietic darkorange1 369, 23 94, 6 91, 3 92, 6 92, 8 0.23 0.203 0.258 0.5882 1.26 0.845 1.88 -0.557 0.635 0.381 0.4193 0.573 0.165 1.99 0.0921 0.561 0.87 0.06068 1.1 0.365 3.29 0.472 0.543 0.385 0.4146 1.6 0.553 4.65 PRS_PLINK_1.99526231496888e.06 282 Hereditary hemolytic anemias Both 77 1087 4 hematopoietic darkorange1 1087, 77 270, 23 272, 24 272, 13 271, 17 -0.0378 0.114 0.741 0.1302 0.963 0.77 1.2 0.0573 0.297 0.847 0.07225 1.06 0.592 1.89 -0.585 0.344 0.0888 1.051 0.557 0.284 1.09 -0.267 0.322 0.407 0.3904 0.766 0.408 1.44 PRS_PLINK_1.99526231496888e.06 282.8 Other hemoglobinopathies Both 33 406 4 hematopoietic darkorange1 406, 33 102, 11 101, 12 101, 3 102, 7 -0.0999 0.173 0.563 0.2496 0.905 0.645 1.27 0.118 0.418 0.778 0.1091 1.13 0.496 2.55 -1.17 0.599 0.0518 1.286 0.312 0.0963 1.01 -0.366 0.474 0.44 0.3567 0.694 0.274 1.75 PRS_PLINK_1.99526231496888e.06 282.9 Other hereditary hemolytic anemias Both 42 618 4 hematopoietic darkorange1 618, 42 156, 12 153, 14 154, 5 155, 11 0.0191 0.157 0.903 0.04419 1.02 0.749 1.39 0.122 0.396 0.758 0.1205 1.13 0.52 2.46 -0.805 0.493 0.102 0.9894 0.447 0.17 1.17 -0.0424 0.412 0.918 0.03712 0.959 0.428 2.15 PRS_PLINK_1.99526231496888e.06 283 Acquired hemolytic anemias Both 59 972 4 hematopoietic darkorange1 972, 59 244, 11 243, 16 242, 18 243, 14 0.0211 0.129 0.87 0.0603 1.02 0.793 1.32 0.35 0.381 0.359 0.4448 1.42 0.672 3 0.466 0.373 0.211 0.675 1.59 0.767 3.31 0.389 0.398 0.327 0.4849 1.48 0.677 3.22 PRS_PLINK_1.99526231496888e.06 283.1 Autoimmune hemolytic anemias Both 45 730 4 hematopoietic darkorange1 730, 45 183, 10 184, 13 182, 13 181, 9 -0.0746 0.152 0.624 0.2051 0.928 0.689 1.25 0.199 0.411 0.628 0.2021 1.22 0.545 2.73 0.251 0.414 0.544 0.2642 1.29 0.571 2.9 -0.0412 0.438 0.925 0.03387 0.96 0.407 2.26 PRS_PLINK_1.99526231496888e.06 284 Aplastic anemia Both 200 3051 4 hematopoietic darkorange1 3051, 200 773, 44 756, 43 758, 47 763, 66 0.161 0.069 0.0197 1.705 1.17 1.03 1.34 -0.000758 0.216 0.997 0.001217 0.999 0.654 1.53 0.0905 0.212 0.67 0.1739 1.09 0.722 1.66 0.428 0.199 0.031 1.508 1.53 1.04 2.27 PRS_PLINK_1.99526231496888e.06 285 Other anemias Both 7059 87513 4 hematopoietic darkorange1 87513, 7059 22006, 1815 21747, 1665 21978, 1748 21754, 1826 0.0236 0.0123 0.0551 1.259 1.02 0.999 1.05 -0.0731 0.0353 0.038 1.42 0.929 0.867 0.996 -0.0296 0.0349 0.396 0.4018 0.971 0.907 1.04 0.0315 0.0346 0.362 0.4411 1.03 0.964 1.1 PRS_PLINK_1.99526231496888e.06 285.1 Acute posthemorrhagic anemia Both 185 2064 4 hematopoietic darkorange1 2064, 185 522, 56 513, 51 512, 31 516, 47 -0.0404 0.0759 0.595 0.2255 0.96 0.828 1.11 -0.0417 0.202 0.837 0.07747 0.959 0.645 1.43 -0.548 0.229 0.0165 1.782 0.578 0.369 0.905 -0.141 0.206 0.495 0.3055 0.869 0.58 1.3 PRS_PLINK_1.99526231496888e.06 285.2 Anemia of chronic disease Both 268 4887 4 hematopoietic darkorange1 4887, 268 1223, 61 1237, 58 1207, 69 1220, 80 0.127 0.0593 0.0317 1.498 1.14 1.01 1.28 -0.0548 0.185 0.767 0.1149 0.947 0.658 1.36 0.144 0.178 0.42 0.377 1.15 0.814 1.64 0.273 0.173 0.114 0.9414 1.31 0.936 1.84 PRS_PLINK_1.99526231496888e.06 285.22 Anemia in neoplastic disease Both 235 2923 4 hematopoietic darkorange1 2923, 235 732, 50 735, 51 725, 60 731, 74 0.134 0.064 0.0357 1.448 1.14 1.01 1.3 0.00205 0.203 0.992 0.003515 1 0.673 1.49 0.194 0.196 0.324 0.4898 1.21 0.826 1.78 0.393 0.188 0.0368 1.434 1.48 1.02 2.14 PRS_PLINK_1.99526231496888e.06 286 Coagulation defects Both 557 6766 4 hematopoietic darkorange1 6766, 557 1716, 139 1684, 143 1674, 158 1691, 117 -0.0385 0.0448 0.39 0.4086 0.962 0.881 1.05 0.0478 0.124 0.699 0.1555 1.05 0.823 1.34 0.153 0.121 0.205 0.6888 1.17 0.92 1.48 -0.163 0.13 0.207 0.6834 0.849 0.659 1.09 PRS_PLINK_1.99526231496888e.06 286.1 Congenital coagulation defects Both 317 3459 4 hematopoietic darkorange1 3459, 317 864, 82 868, 92 872, 83 853, 60 -0.0938 0.061 0.124 0.9063 0.91 0.808 1.03 0.123 0.159 0.437 0.3594 1.13 0.829 1.54 -0.00437 0.162 0.978 0.00947 0.996 0.725 1.37 -0.309 0.175 0.0787 1.104 0.735 0.521 1.04 PRS_PLINK_1.99526231496888e.06 286.11 Von willebrand's disease Both 74 734 4 hematopoietic darkorange1 734, 74 183, 21 183, 23 183, 17 184, 13 -0.176 0.133 0.188 0.7264 0.839 0.646 1.09 0.0417 0.315 0.894 0.04844 1.04 0.563 1.93 -0.2 0.335 0.551 0.259 0.819 0.425 1.58 -0.521 0.355 0.142 0.8476 0.594 0.296 1.19 PRS_PLINK_1.99526231496888e.06 286.12 Congenital deficiency of other clotting factors (including factor VII) Both 201 2233 4 hematopoietic darkorange1 2233, 201 565, 55 551, 54 559, 53 557, 39 -0.0868 0.0752 0.249 0.6047 0.917 0.791 1.06 0.0368 0.2 0.854 0.06847 1.04 0.701 1.54 -0.033 0.199 0.868 0.06129 0.968 0.655 1.43 -0.307 0.215 0.154 0.8133 0.735 0.482 1.12 PRS_PLINK_1.99526231496888e.06 286.13 Congenital factor VIII disorder Both 38 460 4 hematopoietic darkorange1 460, 38 115, 10 115, 12 115, 8 115, 8 -0.0297 0.163 0.856 0.06776 0.971 0.705 1.34 0.186 0.428 0.663 0.1783 1.21 0.52 2.79 -0.206 0.459 0.653 0.1849 0.814 0.331 2 -0.167 0.468 0.721 0.1424 0.846 0.338 2.12 PRS_PLINK_1.99526231496888e.06 286.5 Hemorrhagic disorder due to intrinsic circulating anticoagulants Both 29 569 4 hematopoietic darkorange1 569, 29 144, 4 144, 5 139, 9 142, 11 0.335 0.174 0.0545 1.263 1.4 0.994 1.97 0.157 0.595 0.792 0.1015 1.17 0.365 3.75 0.729 0.558 0.191 0.7183 2.07 0.695 6.18 0.788 0.537 0.142 0.8472 2.2 0.768 6.3 PRS_PLINK_1.99526231496888e.06 286.7 Other and unspecified coagulation defects Both 218 2823 4 hematopoietic darkorange1 2823, 218 706, 52 711, 53 704, 64 702, 49 -0.0254 0.0708 0.719 0.143 0.975 0.849 1.12 -0.0159 0.2 0.937 0.02848 0.984 0.665 1.46 0.191 0.192 0.319 0.4957 1.21 0.831 1.76 -0.0814 0.204 0.69 0.1612 0.922 0.618 1.38 PRS_PLINK_1.99526231496888e.06 287 Purpura and other hemorrhagic conditions Both 868 11543 4 hematopoietic darkorange1 11543, 868 2914, 211 2861, 197 2896, 218 2869, 242 0.0729 0.0346 0.0351 1.454 1.08 1.01 1.15 -0.0512 0.102 0.616 0.2104 0.95 0.778 1.16 0.0424 0.0998 0.671 0.1736 1.04 0.858 1.27 0.152 0.0976 0.12 0.9196 1.16 0.961 1.41 PRS_PLINK_1.99526231496888e.06 287.1 Spontaneous ecchymoses Both 80 916 4 hematopoietic darkorange1 916, 80 230, 22 228, 20 230, 18 228, 20 0.0282 0.114 0.804 0.09465 1.03 0.823 1.29 -0.103 0.315 0.744 0.1285 0.902 0.487 1.67 -0.275 0.329 0.403 0.3943 0.76 0.399 1.45 -0.13 0.316 0.681 0.167 0.878 0.473 1.63 PRS_PLINK_1.99526231496888e.06 287.2 Allergic purpura Both 30 395 4 hematopoietic darkorange1 395, 30 99, 7 99, 6 100, 9 97, 8 0.0566 0.166 0.732 0.1352 1.06 0.765 1.46 -0.11 0.542 0.839 0.07638 0.896 0.309 2.59 0.214 0.485 0.66 0.1807 1.24 0.479 3.2 0.0668 0.501 0.894 0.04873 1.07 0.401 2.85 PRS_PLINK_1.99526231496888e.06 287.3 Thrombocytopenia Both 812 10830 4 hematopoietic darkorange1 10830, 812 2717, 195 2702, 189 2707, 208 2702, 220 0.0539 0.036 0.135 0.8693 1.06 0.983 1.13 -0.0247 0.105 0.814 0.08923 0.976 0.794 1.2 0.0707 0.103 0.493 0.3075 1.07 0.877 1.31 0.123 0.102 0.228 0.6414 1.13 0.926 1.38 PRS_PLINK_1.99526231496888e.06 287.31 Primary thrombocytopenia Both 214 2939 4 hematopoietic darkorange1 2939, 214 738, 57 732, 47 734, 57 734, 53 -0.0554 0.0717 0.44 0.3565 0.946 0.822 1.09 -0.184 0.201 0.359 0.4453 0.832 0.561 1.23 -0.000532 0.192 0.998 0.0009606 0.999 0.686 1.46 -0.0731 0.196 0.709 0.1494 0.93 0.633 1.36 PRS_PLINK_1.99526231496888e.06 287.32 Secondary thrombocytopenia Both 32 507 4 hematopoietic darkorange1 507, 32 127, 8 129, 7 125, 11 126, 6 -0.0319 0.178 0.858 0.06664 0.969 0.683 1.37 -0.147 0.498 0.768 0.1149 0.863 0.325 2.29 0.401 0.462 0.385 0.4149 1.49 0.604 3.69 -0.326 0.512 0.525 0.2802 0.722 0.265 1.97 PRS_PLINK_1.99526231496888e.06 288 Diseases of white blood cells Both 2279 27246 4 hematopoietic darkorange1 27246, 2279 6866, 517 6768, 589 6815, 560 6785, 613 0.0472 0.0215 0.0278 1.556 1.05 1.01 1.09 0.145 0.0626 0.0206 1.687 1.16 1.02 1.31 0.0903 0.0633 0.154 0.8137 1.09 0.967 1.24 0.184 0.0622 0.00312 2.506 1.2 1.06 1.36 PRS_PLINK_1.99526231496888e.06 288.1 Decreased white blood cell count Both 1930 22983 4 hematopoietic darkorange1 22983, 1930 5755, 442 5741, 501 5732, 465 5745, 522 0.043 0.0234 0.0654 1.185 1.04 0.997 1.09 0.128 0.0678 0.0598 1.223 1.14 0.995 1.3 0.0603 0.069 0.382 0.418 1.06 0.928 1.22 0.167 0.0673 0.0131 1.883 1.18 1.04 1.35 PRS_PLINK_1.99526231496888e.06 288.11 Neutropenia Both 1937 23042 4 hematopoietic darkorange1 23042, 1937 5775, 443 5744, 504 5780, 467 5733, 523 0.0415 0.0233 0.0753 1.123 1.04 0.996 1.09 0.134 0.0677 0.0475 1.323 1.14 1 1.31 0.0569 0.0688 0.409 0.3887 1.06 0.925 1.21 0.172 0.0672 0.0104 1.982 1.19 1.04 1.36 PRS_PLINK_1.99526231496888e.06 288.3 Eosinophilia Both 40 499 4 hematopoietic darkorange1 499, 40 126, 7 125, 6 122, 16 125, 11 0.258 0.153 0.0917 1.038 1.29 0.959 1.75 -0.309 0.521 0.554 0.2566 0.734 0.264 2.04 0.805 0.444 0.0702 1.154 2.24 0.936 5.34 0.456 0.467 0.329 0.4824 1.58 0.631 3.94 PRS_PLINK_1.99526231496888e.06 289 Other diseases of blood and blood-forming organs Both 474 6221 4 hematopoietic darkorange1 6221, 474 1568, 108 1541, 118 1572, 117 1536, 131 0.0715 0.0472 0.13 0.8873 1.07 0.979 1.18 0.0954 0.137 0.487 0.3126 1.1 0.841 1.44 0.0819 0.137 0.551 0.2592 1.09 0.829 1.42 0.214 0.134 0.11 0.9587 1.24 0.953 1.61 PRS_PLINK_1.99526231496888e.06 289.3 Personal history of diseases of blood and blood-forming organs Both 164 2167 4 hematopoietic darkorange1 2167, 164 543, 36 542, 51 544, 40 535, 37 -0.0109 0.0807 0.893 0.04918 0.989 0.845 1.16 0.318 0.223 0.155 0.8102 1.37 0.887 2.13 0.0967 0.233 0.678 0.1687 1.1 0.698 1.74 0.0664 0.239 0.781 0.1073 1.07 0.669 1.71 PRS_PLINK_1.99526231496888e.06 289.4 Lymphadenitis Both 1575 18736 4 hematopoietic darkorange1 18736, 1575 4700, 380 4666, 392 4714, 394 4650, 408 0.0341 0.0259 0.188 0.7249 1.03 0.983 1.09 0.037 0.0748 0.621 0.2072 1.04 0.896 1.2 0.038 0.0747 0.611 0.2137 1.04 0.897 1.2 0.0871 0.0743 0.241 0.6178 1.09 0.943 1.26 PRS_PLINK_1.99526231496888e.06 289.5 Diseases of spleen Both 291 3627 4 hematopoietic darkorange1 3627, 291 912, 81 905, 63 901, 82 906, 65 -0.038 0.0607 0.532 0.2743 0.963 0.855 1.08 -0.259 0.173 0.134 0.8738 0.771 0.55 1.08 0.0263 0.162 0.871 0.05993 1.03 0.747 1.41 -0.208 0.171 0.225 0.6481 0.812 0.58 1.14 PRS_PLINK_1.99526231496888e.06 289.8 Polycythemia, secondary Both 133 2006 4 hematopoietic darkorange1 2006, 133 504, 26 500, 36 500, 34 502, 37 0.0619 0.0845 0.464 0.3339 1.06 0.902 1.26 0.298 0.261 0.254 0.5952 1.35 0.808 2.25 0.263 0.263 0.317 0.4994 1.3 0.777 2.18 0.389 0.26 0.134 0.8728 1.48 0.887 2.45 PRS_PLINK_1.99526231496888e.06 289.9 Abnormality of red blood cells Both 38 649 4 hematopoietic darkorange1 649, 38 165, 2 160, 13 163, 10 161, 13 0.256 0.158 0.106 0.9756 1.29 0.947 1.76 1.58 0.651 0.0153 1.817 4.85 1.35 17.4 1.37 0.646 0.0335 1.475 3.95 1.11 14 1.62 0.644 0.0117 1.933 5.07 1.44 17.9 PRS_PLINK_1.99526231496888e.06 290 Delirium dementia and amnestic and other cognitive disorders Both 1010 12458 5 mental disorders magenta 12458, 1010 3111, 229 3137, 287 3141, 273 3065, 221 -0.0288 0.0327 0.379 0.4213 0.972 0.911 1.04 0.22 0.0919 0.0165 1.781 1.25 1.04 1.49 0.165 0.0929 0.0759 1.12 1.18 0.983 1.41 -0.0167 0.0975 0.864 0.06353 0.983 0.812 1.19 PRS_PLINK_1.99526231496888e.06 290.1 Dementias Both 540 6269 5 mental disorders magenta 6269, 540 1582, 126 1557, 145 1562, 158 1567, 111 -0.0191 0.0447 0.669 0.1748 0.981 0.899 1.07 0.157 0.126 0.213 0.6716 1.17 0.914 1.5 0.251 0.124 0.0432 1.364 1.29 1.01 1.64 -0.0932 0.135 0.489 0.3108 0.911 0.7 1.19 PRS_PLINK_1.99526231496888e.06 290.11 Alzheimer's disease Both 252 2750 5 mental disorders magenta 2750, 252 688, 51 694, 69 688, 85 680, 47 0.00124 0.0656 0.985 0.006579 1 0.88 1.14 0.298 0.191 0.118 0.9273 1.35 0.927 1.96 0.503 0.183 0.00612 2.214 1.65 1.15 2.37 -0.0331 0.207 0.873 0.05896 0.967 0.644 1.45 PRS_PLINK_1.99526231496888e.06 290.16 Vascular dementia Both 99 1219 5 mental disorders magenta 1219, 99 307, 27 305, 28 302, 23 305, 21 -0.0505 0.101 0.617 0.2095 0.951 0.78 1.16 0.0745 0.275 0.787 0.1042 1.08 0.628 1.85 -0.14 0.287 0.626 0.2031 0.87 0.496 1.53 -0.221 0.294 0.452 0.3448 0.801 0.45 1.43 PRS_PLINK_1.99526231496888e.06 290.2 Delirium due to conditions classified elsewhere Both 328 4252 5 mental disorders magenta 4252, 328 1077, 85 1049, 95 1062, 73 1063, 75 -0.0988 0.0587 0.0924 1.035 0.906 0.807 1.02 0.13 0.154 0.401 0.3968 1.14 0.841 1.54 -0.127 0.164 0.439 0.3577 0.881 0.639 1.21 -0.112 0.163 0.493 0.3072 0.894 0.65 1.23 PRS_PLINK_1.99526231496888e.06 290.3 Other persistent mental disorders due to conditions classified elsewhere Both 42 558 5 mental disorders magenta 558, 42 140, 11 140, 13 139, 5 139, 13 0.0503 0.149 0.736 0.1333 1.05 0.785 1.41 0.183 0.414 0.659 0.1811 1.2 0.533 2.7 -0.732 0.512 0.153 0.8152 0.481 0.176 1.31 0.222 0.418 0.596 0.2248 1.25 0.55 2.83 PRS_PLINK_1.99526231496888e.06 291 Other specified nonpsychotic and/or transient mental disorders Both 499 6087 5 mental disorders magenta 6087, 499 1520, 136 1536, 131 1524, 120 1505, 112 -0.0407 0.0472 0.389 0.4102 0.96 0.875 1.05 -0.0481 0.127 0.705 0.1518 0.953 0.743 1.22 -0.12 0.13 0.354 0.4506 0.887 0.688 1.14 -0.176 0.132 0.184 0.736 0.839 0.648 1.09 PRS_PLINK_1.99526231496888e.06 291.1 Transient mental disorders due to conditions classified elsewhere Both 95 1045 5 mental disorders magenta 1045, 95 273, 38 250, 14 262, 14 260, 29 0.0429 0.108 0.691 0.1607 1.04 0.845 1.29 -0.842 0.317 0.00789 2.103 0.431 0.232 0.802 -0.883 0.315 0.0051 2.293 0.413 0.223 0.767 -0.2 0.259 0.44 0.3563 0.819 0.493 1.36 PRS_PLINK_1.99526231496888e.06 291.4 Specific nonpsychotic mental disorders due to brain damage Both 163 1978 5 mental disorders magenta 1978, 163 494, 46 496, 43 493, 44 494, 30 -0.12 0.0837 0.152 0.8179 0.887 0.753 1.05 -0.0613 0.219 0.78 0.108 0.941 0.612 1.45 -0.0548 0.218 0.801 0.09631 0.947 0.618 1.45 -0.398 0.239 0.0955 1.02 0.672 0.421 1.07 PRS_PLINK_1.99526231496888e.06 291.8 Alteration of consciousness Both 255 3192 5 mental disorders magenta 3192, 255 799, 55 802, 70 796, 73 794, 57 0.0103 0.0652 0.874 0.05845 1.01 0.889 1.15 0.248 0.185 0.181 0.7411 1.28 0.891 1.84 0.284 0.183 0.121 0.9161 1.33 0.927 1.9 0.0444 0.194 0.819 0.0867 1.05 0.715 1.53 PRS_PLINK_1.99526231496888e.06 292 Neurological disorders Both 2712 31905 5 mental disorders magenta 31905, 2712 8009, 655 7941, 650 7980, 701 7965, 706 0.0379 0.0195 0.0523 1.281 1.04 1 1.08 0.000651 0.0575 0.991 0.003937 1 0.894 1.12 0.0728 0.0565 0.198 0.703 1.08 0.963 1.2 0.0826 0.0565 0.144 0.8425 1.09 0.972 1.21 PRS_PLINK_1.99526231496888e.06 292.1 Aphasia/speech disturbance Both 906 10596 5 mental disorders magenta 10596, 906 2653, 219 2654, 226 2651, 234 2636, 227 0.0232 0.0337 0.491 0.3087 1.02 0.958 1.09 0.0294 0.0984 0.765 0.1163 1.03 0.849 1.25 0.069 0.0977 0.48 0.3188 1.07 0.885 1.3 0.0487 0.0984 0.621 0.2072 1.05 0.866 1.27 PRS_PLINK_1.99526231496888e.06 292.2 Mild cognitive impairment Both 99 1299 5 mental disorders magenta 1299, 99 328, 22 322, 31 323, 28 325, 18 -0.0769 0.104 0.462 0.3355 0.926 0.755 1.14 0.306 0.285 0.282 0.5494 1.36 0.777 2.38 0.266 0.288 0.356 0.4488 1.3 0.742 2.29 -0.173 0.316 0.584 0.2333 0.841 0.452 1.56 PRS_PLINK_1.99526231496888e.06 292.3 Memory loss Both 469 4916 5 mental disorders magenta 4916, 469 1239, 122 1236, 111 1213, 112 1226, 124 0.0147 0.0473 0.756 0.1216 1.01 0.925 1.11 -0.0935 0.136 0.493 0.3069 0.911 0.697 1.19 -0.0668 0.136 0.624 0.2048 0.935 0.716 1.22 0.0313 0.133 0.814 0.08929 1.03 0.795 1.34 PRS_PLINK_1.99526231496888e.06 292.4 Altered mental status Both 1211 14671 5 mental disorders magenta 14671, 1211 3664, 288 3681, 294 3656, 323 3666, 306 0.0381 0.0291 0.191 0.719 1.04 0.981 1.1 0.0146 0.0859 0.865 0.06289 1.01 0.857 1.2 0.119 0.0842 0.158 0.8018 1.13 0.955 1.33 0.0617 0.0852 0.469 0.3286 1.06 0.9 1.26 PRS_PLINK_1.99526231496888e.06 292.6 Hallucinations Both 171 2166 5 mental disorders magenta 2166, 171 542, 39 543, 37 540, 47 540, 48 0.126 0.0765 0.0984 1.007 1.13 0.977 1.32 -0.0775 0.233 0.74 0.1309 0.925 0.586 1.46 0.208 0.222 0.349 0.4574 1.23 0.797 1.9 0.223 0.221 0.312 0.5055 1.25 0.811 1.93 PRS_PLINK_1.99526231496888e.06 293 Symptoms involving head and neck Both 1419 15198 5 mental disorders magenta 15198, 1419 3815, 336 3780, 354 3807, 358 3790, 370 0.0261 0.0273 0.339 0.47 1.03 0.973 1.08 0.0619 0.0794 0.435 0.3612 1.06 0.911 1.24 0.0622 0.0792 0.432 0.3642 1.06 0.911 1.24 0.106 0.0787 0.176 0.7537 1.11 0.953 1.3 PRS_PLINK_1.99526231496888e.06 293.1 Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS] Both 605 6623 5 mental disorders magenta 6623, 605 1658, 137 1668, 178 1659, 139 1636, 150 -0.00632 0.0424 0.881 0.05481 0.994 0.914 1.08 0.253 0.118 0.0325 1.488 1.29 1.02 1.62 0.0149 0.125 0.905 0.04348 1.02 0.795 1.3 0.107 0.123 0.385 0.4145 1.11 0.875 1.42 PRS_PLINK_1.99526231496888e.06 295 Schizophrenia and other psychotic disorders Both 493 6382 5 mental disorders magenta 6382, 493 1594, 132 1604, 125 1606, 96 1576, 140 -0.0292 0.0475 0.539 0.2686 0.971 0.885 1.07 -0.0621 0.129 0.63 0.2007 0.94 0.73 1.21 -0.324 0.138 0.0187 1.729 0.723 0.552 0.947 0.0808 0.126 0.521 0.2831 1.08 0.847 1.39 PRS_PLINK_1.99526231496888e.06 295.1 Schizophrenia Both 326 4364 5 mental disorders magenta 4364, 326 1091, 85 1091, 85 1096, 53 1085, 103 0.00287 0.0573 0.96 0.01767 1 0.896 1.12 6.33e-05 0.158 1 0.0001389 1 0.734 1.36 -0.474 0.178 0.00777 2.109 0.622 0.439 0.882 0.206 0.152 0.175 0.7581 1.23 0.913 1.65 PRS_PLINK_1.99526231496888e.06 295.2 Paranoid disorders Both 111 1363 5 mental disorders magenta 1363, 111 345, 30 337, 27 339, 25 341, 29 0.0122 0.0977 0.901 0.04529 1.01 0.836 1.23 -0.103 0.27 0.704 0.1525 0.902 0.531 1.53 -0.142 0.275 0.607 0.2167 0.868 0.506 1.49 0.00343 0.266 0.99 0.004487 1 0.595 1.69 PRS_PLINK_1.99526231496888e.06 295.3 Psychosis Both 101 1317 5 mental disorders magenta 1317, 101 330, 26 328, 30 329, 23 329, 22 -0.144 0.107 0.179 0.7468 0.866 0.702 1.07 0.114 0.275 0.678 0.169 1.12 0.654 1.92 -0.101 0.288 0.727 0.1385 0.904 0.514 1.59 -0.175 0.293 0.549 0.2601 0.839 0.473 1.49 PRS_PLINK_1.99526231496888e.06 296 Mood disorders Both 8082 94942 5 mental disorders magenta 94942, 8082 23923, 1963 23653, 1925 23705, 2038 23632, 2155 0.0412 0.0115 0.000358 3.446 1.04 1.02 1.07 -0.0063 0.0334 0.85 0.07045 0.994 0.931 1.06 0.0498 0.0329 0.131 0.8842 1.05 0.985 1.12 0.115 0.0326 0.000413 3.384 1.12 1.05 1.2 PRS_PLINK_1.99526231496888e.06 296.1 Bipolar Both 632 8089 5 mental disorders magenta 8089, 632 2022, 159 2040, 145 2043, 154 1979, 174 0.0435 0.0408 0.287 0.5421 1.04 0.964 1.13 -0.0921 0.119 0.437 0.3591 0.912 0.723 1.15 -0.0373 0.117 0.75 0.1251 0.963 0.766 1.21 0.13 0.114 0.254 0.5959 1.14 0.911 1.42 PRS_PLINK_1.99526231496888e.06 296.2 Depression Both 7697 90087 5 mental disorders magenta 90087, 7697 22663, 1861 22433, 1824 22488, 1964 22475, 2047 0.0415 0.0118 0.000457 3.34 1.04 1.02 1.07 -0.00812 0.0343 0.813 0.09011 0.992 0.927 1.06 0.0643 0.0337 0.0563 1.249 1.07 0.998 1.14 0.112 0.0334 0.000817 3.088 1.12 1.05 1.19 PRS_PLINK_1.99526231496888e.06 296.22 Major depressive disorder Both 228 2742 5 mental disorders magenta 2742, 228 693, 51 680, 57 683, 58 686, 62 0.0083 0.0688 0.904 0.04387 1.01 0.881 1.15 0.125 0.198 0.527 0.278 1.13 0.769 1.67 0.152 0.197 0.44 0.3566 1.16 0.792 1.71 0.207 0.194 0.286 0.5438 1.23 0.841 1.8 PRS_PLINK_1.99526231496888e.06 297.2 Suicide or self-inflicted injury Both 208 2413 5 mental disorders magenta 2413, 208 604, 67 602, 49 607, 42 599, 50 -0.09 0.0733 0.22 0.6576 0.914 0.792 1.06 -0.303 0.195 0.119 0.924 0.738 0.504 1.08 -0.48 0.203 0.0181 1.742 0.619 0.415 0.921 -0.285 0.194 0.141 0.8493 0.752 0.514 1.1 PRS_PLINK_1.99526231496888e.06 300 Anxiety disorders Both 4624 51851 5 mental disorders magenta 51851, 4624 12968, 1152 13048, 1115 13058, 1207 12758, 1150 0.00885 0.0153 0.563 0.2491 1.01 0.979 1.04 -0.0382 0.0438 0.383 0.4163 0.963 0.883 1.05 0.043 0.043 0.318 0.4977 1.04 0.959 1.14 0.0165 0.0435 0.704 0.1524 1.02 0.934 1.11 PRS_PLINK_1.99526231496888e.06 300.1 Anxiety disorder Both 4282 47836 5 mental disorders magenta 47836, 4282 11948, 1075 12005, 1028 12084, 1104 11779, 1075 0.00939 0.0159 0.556 0.2552 1.01 0.978 1.04 -0.0485 0.0455 0.286 0.5439 0.953 0.871 1.04 0.0176 0.0447 0.694 0.1587 1.02 0.932 1.11 0.0163 0.0451 0.717 0.1444 1.02 0.93 1.11 PRS_PLINK_1.99526231496888e.06 300.11 Generalized anxiety disorder Both 109 1153 5 mental disorders magenta 1153, 109 293, 27 284, 29 291, 31 284, 22 -0.0655 0.1 0.513 0.2903 0.937 0.77 1.14 0.0863 0.275 0.754 0.1229 1.09 0.636 1.87 0.135 0.272 0.62 0.2076 1.14 0.672 1.95 -0.161 0.293 0.583 0.2347 0.851 0.48 1.51 PRS_PLINK_1.99526231496888e.06 300.12 Agorophobia, social phobia, and panic disorder Both 474 5403 5 mental disorders magenta 5403, 474 1361, 108 1341, 118 1359, 133 1340, 115 0.0437 0.0479 0.361 0.4419 1.04 0.951 1.15 0.103 0.138 0.455 0.3416 1.11 0.846 1.45 0.217 0.134 0.107 0.971 1.24 0.954 1.62 0.0829 0.139 0.549 0.2601 1.09 0.828 1.43 PRS_PLINK_1.99526231496888e.06 300.13 Phobia Both 326 3766 5 mental disorders magenta 3766, 326 942, 71 943, 79 938, 95 942, 81 0.033 0.0576 0.566 0.2468 1.03 0.923 1.16 0.112 0.168 0.505 0.2964 1.12 0.804 1.56 0.314 0.163 0.0535 1.272 1.37 0.995 1.88 0.131 0.168 0.434 0.3629 1.14 0.821 1.58 PRS_PLINK_1.99526231496888e.06 300.3 Obsessive-compulsive disorders Both 97 1080 5 mental disorders magenta 1080, 97 272, 26 268, 32 273, 20 267, 19 -0.198 0.113 0.0797 1.099 0.821 0.658 1.02 0.187 0.273 0.494 0.3064 1.21 0.706 2.06 -0.22 0.301 0.465 0.3328 0.803 0.445 1.45 -0.31 0.306 0.311 0.5072 0.733 0.402 1.34 PRS_PLINK_1.99526231496888e.06 300.4 Dysthymic disorder Both 37 419 5 mental disorders magenta 419, 37 104, 6 106, 5 103, 16 105, 10 0.234 0.159 0.14 0.8524 1.26 0.926 1.72 -0.194 0.554 0.727 0.1386 0.824 0.278 2.44 0.917 0.467 0.0499 1.302 2.5 1 6.25 0.401 0.491 0.415 0.3822 1.49 0.57 3.91 PRS_PLINK_1.99526231496888e.06 300.8 Acute reaction to stress Both 86 965 5 mental disorders magenta 965, 86 244, 25 239, 17 241, 20 241, 24 0.0481 0.109 0.66 0.1806 1.05 0.847 1.3 -0.326 0.318 0.307 0.5135 0.722 0.387 1.35 -0.229 0.306 0.454 0.3428 0.795 0.436 1.45 -0.0635 0.296 0.83 0.08098 0.938 0.526 1.68 PRS_PLINK_1.99526231496888e.06 300.9 Posttraumatic stress disorder Both 80 891 5 mental disorders magenta 891, 80 227, 17 220, 19 223, 22 221, 22 0.125 0.116 0.28 0.5524 1.13 0.903 1.42 0.137 0.334 0.683 0.1659 1.15 0.596 2.21 0.26 0.324 0.423 0.3741 1.3 0.687 2.45 0.247 0.325 0.447 0.3493 1.28 0.677 2.42 PRS_PLINK_1.99526231496888e.06 301 Personality disorders Both 203 2700 5 mental disorders magenta 2700, 203 683, 56 668, 33 681, 57 668, 57 0.131 0.0709 0.0639 1.195 1.14 0.992 1.31 -0.513 0.223 0.0213 1.671 0.599 0.387 0.927 -0.00256 0.194 0.989 0.0046 0.997 0.682 1.46 0.0402 0.194 0.835 0.07815 1.04 0.712 1.52 PRS_PLINK_1.99526231496888e.06 301.2 Antisocial/borderline personality disorder Both 74 1010 5 mental disorders magenta 1010, 74 256, 17 249, 11 254, 24 251, 22 0.208 0.115 0.0721 1.142 1.23 0.982 1.54 -0.419 0.379 0.27 0.5693 0.658 0.313 1.38 0.351 0.317 0.269 0.5705 1.42 0.763 2.65 0.261 0.323 0.42 0.3767 1.3 0.689 2.45 PRS_PLINK_1.99526231496888e.06 302 Sexual and gender identity disorders Both 162 1890 5 mental disorders magenta 1890, 162 477, 35 468, 36 472, 52 473, 39 0.0434 0.0806 0.59 0.2288 1.04 0.892 1.22 0.0369 0.241 0.879 0.05622 1.04 0.646 1.67 0.41 0.226 0.0693 1.159 1.51 0.968 2.34 0.0914 0.238 0.701 0.1543 1.1 0.687 1.75 PRS_PLINK_1.99526231496888e.06 303 Psychogenic and somatoform disorders Both 327 3543 5 mental disorders magenta 3543, 327 895, 65 878, 90 903, 94 867, 78 0.0762 0.0572 0.183 0.7375 1.08 0.965 1.21 0.337 0.168 0.0452 1.345 1.4 1.01 1.95 0.366 0.167 0.0288 1.54 1.44 1.04 2 0.182 0.174 0.294 0.5315 1.2 0.854 1.69 PRS_PLINK_1.99526231496888e.06 303.3 Psychogenic disorder Both 252 2625 5 mental disorders magenta 2625, 252 672, 52 643, 70 654, 67 656, 63 0.0488 0.0656 0.456 0.3407 1.05 0.923 1.19 0.332 0.189 0.0792 1.101 1.39 0.962 2.02 0.289 0.192 0.131 0.8813 1.34 0.917 1.94 0.168 0.194 0.387 0.4124 1.18 0.809 1.73 PRS_PLINK_1.99526231496888e.06 303.4 Somatoform disorder Both 82 960 5 mental disorders magenta 960, 82 242, 18 240, 22 238, 24 240, 18 0.0635 0.111 0.567 0.2466 1.07 0.857 1.32 0.221 0.32 0.49 0.3099 1.25 0.666 2.34 0.349 0.317 0.27 0.5679 1.42 0.762 2.64 0.0246 0.333 0.941 0.02634 1.02 0.534 1.97 PRS_PLINK_1.99526231496888e.06 304 Adjustment reaction Both 202 2288 5 mental disorders magenta 2288, 202 577, 64 569, 42 574, 47 567, 49 -0.0593 0.0763 0.437 0.3593 0.942 0.812 1.09 -0.407 0.205 0.0463 1.334 0.665 0.446 0.993 -0.307 0.198 0.122 0.9136 0.736 0.499 1.09 -0.243 0.197 0.218 0.6613 0.785 0.533 1.15 PRS_PLINK_1.99526231496888e.06 305.2 Eating disorder Both 73 763 5 mental disorders magenta 763, 73 192, 9 190, 32 196, 15 185, 17 -0.0025 0.124 0.984 0.007051 0.997 0.782 1.27 1.25 0.381 0.000977 3.01 3.51 1.66 7.39 0.511 0.412 0.214 0.6687 1.67 0.744 3.74 0.642 0.403 0.111 0.9561 1.9 0.863 4.18 PRS_PLINK_1.99526231496888e.06 306 Other mental disorder Both 17030 167354 5 mental disorders magenta 167354, 17030 41797, 4098 41847, 4123 41960, 4394 41692, 4407 0.0205 0.00797 0.01 2 1.02 1 1.04 0.00146 0.0231 0.95 0.02247 1 0.957 1.05 0.0568 0.0228 0.0128 1.892 1.06 1.01 1.11 0.0557 0.0228 0.0148 1.83 1.06 1.01 1.11 PRS_PLINK_1.99526231496888e.06 306.9 Tension headache Both 218 2489 5 mental disorders magenta 2489, 218 630, 55 615, 48 622, 63 622, 52 0.0205 0.0714 0.774 0.1112 1.02 0.887 1.17 -0.108 0.203 0.594 0.2263 0.897 0.603 1.34 0.151 0.191 0.429 0.3675 1.16 0.8 1.69 -0.0524 0.199 0.793 0.1008 0.949 0.642 1.4 PRS_PLINK_1.99526231496888e.06 313 Pervasive developmental disorders Both 54 593 5 mental disorders magenta 593, 54 149, 11 149, 14 148, 18 147, 11 0.0176 0.136 0.897 0.04717 1.02 0.78 1.33 0.359 0.408 0.378 0.422 1.43 0.644 3.19 0.48 0.384 0.212 0.6745 1.62 0.761 3.43 0.177 0.423 0.676 0.1698 1.19 0.52 2.74 PRS_PLINK_1.99526231496888e.06 313.3 Autism Both 39 409 5 mental disorders magenta 409, 39 103, 7 106, 7 98, 14 102, 11 0.184 0.153 0.229 0.6403 1.2 0.891 1.62 0.0543 0.521 0.917 0.03763 1.06 0.38 2.93 0.673 0.465 0.148 0.8287 1.96 0.787 4.88 0.624 0.48 0.194 0.7118 1.87 0.728 4.79 PRS_PLINK_1.99526231496888e.06 315 Develomental delays and disorders Both 200 2513 5 mental disorders magenta 2513, 200 631, 57 629, 46 632, 41 620, 56 0.0259 0.0726 0.722 0.1416 1.03 0.89 1.18 -0.214 0.204 0.293 0.5326 0.807 0.542 1.2 -0.313 0.21 0.136 0.8669 0.732 0.485 1.1 0.00421 0.195 0.983 0.007529 1 0.685 1.47 PRS_PLINK_1.99526231496888e.06 315.1 Learning disorder Both 83 1248 5 mental disorders magenta 1248, 83 312, 17 313, 27 321, 19 302, 20 -0.0174 0.113 0.877 0.05699 0.983 0.788 1.23 0.484 0.31 0.118 0.9267 1.62 0.884 2.98 0.107 0.33 0.746 0.1271 1.11 0.582 2.13 0.203 0.327 0.536 0.271 1.22 0.645 2.33 PRS_PLINK_1.99526231496888e.06 315.2 Speech and language disorder Both 50 615 5 mental disorders magenta 615, 50 156, 16 151, 15 153, 5 154, 14 -0.0289 0.149 0.846 0.07254 0.972 0.726 1.3 -0.0246 0.362 0.946 0.02422 0.976 0.48 1.98 -1.02 0.483 0.035 1.456 0.361 0.14 0.931 -0.148 0.373 0.691 0.1607 0.862 0.415 1.79 PRS_PLINK_1.99526231496888e.06 316 Substance addiction and disorders Both 3375 39026 5 mental disorders magenta 39026, 3375 9800, 831 9700, 841 9763, 842 9750, 861 0.0119 0.0178 0.502 0.2989 1.01 0.977 1.05 0.0217 0.0509 0.671 0.1735 1.02 0.925 1.13 0.0189 0.0509 0.711 0.1483 1.02 0.922 1.13 0.0456 0.0507 0.368 0.4336 1.05 0.948 1.16 PRS_PLINK_1.99526231496888e.06 316.1 Polyneuropathy due to drugs Both 31 449 5 mental disorders magenta 449, 31 114, 9 111, 5 115, 7 109, 10 0.0114 0.177 0.949 0.0229 1.01 0.715 1.43 -0.413 0.529 0.435 0.3618 0.662 0.235 1.86 -0.0515 0.5 0.918 0.03724 0.95 0.357 2.53 0.174 0.457 0.704 0.1525 1.19 0.486 2.92 PRS_PLINK_1.99526231496888e.06 317 Alcohol-related disorders Both 8591 92459 5 mental disorders magenta 92459, 8591 23110, 2165 23131, 2140 23259, 2132 22931, 2152 0.00604 0.0112 0.591 0.2282 1.01 0.984 1.03 -0.0128 0.0319 0.688 0.1622 0.987 0.928 1.05 -0.0208 0.0319 0.515 0.2885 0.979 0.92 1.04 0.00575 0.0319 0.857 0.06709 1.01 0.945 1.07 PRS_PLINK_1.99526231496888e.06 317.1 Alcoholism Both 6050 64215 5 mental disorders magenta 64215, 6050 16033, 1542 16160, 1508 16013, 1494 15988, 1504 0.00075 0.0134 0.955 0.01983 1 0.975 1.03 -0.0303 0.0379 0.424 0.3729 0.97 0.901 1.04 -0.0296 0.038 0.435 0.3611 0.971 0.901 1.05 -0.018 0.038 0.635 0.1974 0.982 0.912 1.06 PRS_PLINK_1.99526231496888e.06 317.11 Alcoholic liver damage Both 450 6050 5 mental disorders magenta 6050, 450 1514, 107 1511, 119 1542, 112 1482, 112 0.0021 0.0479 0.965 0.01545 1 0.912 1.1 0.115 0.137 0.401 0.397 1.12 0.857 1.47 0.0196 0.139 0.888 0.05172 1.02 0.776 1.34 0.0658 0.139 0.637 0.1962 1.07 0.813 1.4 PRS_PLINK_1.99526231496888e.06 318 Tobacco use disorder Both 11090 136722 5 mental disorders magenta 136722, 11090 34405, 2752 34013, 2620 34405, 2799 33858, 2915 0.0406 0.00977 3.24e-05 4.489 1.04 1.02 1.06 -0.0367 0.0284 0.196 0.7085 0.964 0.912 1.02 0.0207 0.0279 0.46 0.3374 1.02 0.966 1.08 0.086 0.0277 0.00191 2.718 1.09 1.03 1.15 PRS_PLINK_1.99526231496888e.06 320 Meningitis Both 314 3432 6 neurological darkblue 3432, 314 858, 78 860, 81 857, 76 857, 79 0.00964 0.0588 0.87 0.06057 1.01 0.9 1.13 0.0284 0.165 0.863 0.064 1.03 0.745 1.42 -0.0419 0.167 0.802 0.09563 0.959 0.691 1.33 0.0226 0.166 0.892 0.04983 1.02 0.739 1.42 PRS_PLINK_1.99526231496888e.06 323 Encephalitis Both 242 2561 6 neurological darkblue 2561, 242 641, 54 639, 68 642, 55 637, 65 0.0794 0.0654 0.224 0.6488 1.08 0.952 1.23 0.253 0.189 0.181 0.7426 1.29 0.889 1.87 0.0498 0.198 0.801 0.09649 1.05 0.714 1.55 0.206 0.191 0.28 0.5522 1.23 0.845 1.79 PRS_PLINK_1.99526231496888e.06 323.2 Acute (transverse) myelitis Both 62 590 6 neurological darkblue 590, 62 148, 16 147, 14 147, 15 148, 17 0.162 0.124 0.191 0.7198 1.18 0.923 1.5 -0.165 0.374 0.659 0.1811 0.848 0.407 1.77 -0.028 0.372 0.94 0.02684 0.972 0.469 2.02 0.0823 0.359 0.819 0.08677 1.09 0.537 2.2 PRS_PLINK_1.99526231496888e.06 324 Other CNS infection and poliomyelitis Both 186 2017 6 neurological darkblue 2017, 186 509, 41 501, 47 515, 42 490, 56 0.162 0.0748 0.03 1.523 1.18 1.02 1.36 0.141 0.22 0.521 0.2834 1.15 0.749 1.77 0.0188 0.225 0.934 0.02988 1.02 0.655 1.58 0.348 0.212 0.1 0.998 1.42 0.935 2.15 PRS_PLINK_1.99526231496888e.06 327 Sleep disorders Both 753 8299 6 neurological darkblue 8299, 753 2088, 173 2064, 173 2083, 196 2063, 211 0.0938 0.0368 0.0107 1.971 1.1 1.02 1.18 0.00953 0.111 0.932 0.03066 1.01 0.811 1.26 0.124 0.109 0.252 0.5981 1.13 0.915 1.4 0.205 0.107 0.0556 1.255 1.23 0.995 1.51 PRS_PLINK_1.99526231496888e.06 327.3 Sleep apnea Both 2509 31613 6 neurological darkblue 31613, 2509 7893, 630 7904, 597 7905, 630 7898, 652 0.0331 0.0205 0.105 0.977 1.03 0.993 1.08 -0.0535 0.0592 0.366 0.4362 0.948 0.844 1.06 6.12e-05 0.0585 0.999 0.0003625 1 0.892 1.12 0.0376 0.0581 0.517 0.2865 1.04 0.927 1.16 PRS_PLINK_1.99526231496888e.06 327.4 Insomnia Both 106 1206 6 neurological darkblue 1206, 106 302, 27 302, 23 304, 25 298, 31 0.0815 0.0977 0.405 0.393 1.08 0.896 1.31 -0.13 0.29 0.654 0.1842 0.878 0.498 1.55 -0.0862 0.284 0.761 0.1185 0.917 0.526 1.6 0.159 0.27 0.557 0.2544 1.17 0.69 1.99 PRS_PLINK_1.99526231496888e.06 327.41 Organic or persistent insomnia Both 89 1012 6 neurological darkblue 1012, 89 253, 18 254, 20 252, 23 253, 28 0.161 0.105 0.125 0.903 1.17 0.956 1.44 0.07 0.326 0.83 0.0809 1.07 0.566 2.03 0.201 0.318 0.528 0.2777 1.22 0.655 2.28 0.429 0.307 0.162 0.7902 1.54 0.842 2.8 PRS_PLINK_1.99526231496888e.06 331 Other cerebral degenerations Both 688 7941 6 neurological darkblue 7941, 688 2011, 176 1956, 159 1990, 182 1980, 171 0.0162 0.0399 0.684 0.165 1.02 0.94 1.1 -0.074 0.113 0.514 0.2887 0.929 0.744 1.16 0.0482 0.11 0.662 0.1794 1.05 0.846 1.3 0.00503 0.112 0.964 0.01587 1.01 0.807 1.25 PRS_PLINK_1.99526231496888e.06 331.1 Hydrocephalus Both 320 3620 6 neurological darkblue 3620, 320 905, 96 905, 67 907, 79 901, 78 -0.0654 0.06 0.276 0.5585 0.937 0.833 1.05 -0.357 0.165 0.0303 1.519 0.7 0.507 0.967 -0.193 0.158 0.221 0.6553 0.825 0.605 1.12 -0.173 0.159 0.277 0.5578 0.841 0.616 1.15 PRS_PLINK_1.99526231496888e.06 331.9 Cerebral degeneration, unspecified Both 245 2859 6 neurological darkblue 2859, 245 714, 48 725, 63 709, 70 710, 64 0.112 0.0652 0.0869 1.061 1.12 0.984 1.27 0.264 0.196 0.179 0.7477 1.3 0.886 1.91 0.39 0.193 0.0439 1.357 1.48 1.01 2.16 0.308 0.196 0.117 0.9302 1.36 0.925 2 PRS_PLINK_1.99526231496888e.06 332 Parkinson's disease Both 696 7283 6 neurological darkblue 7283, 696 1819, 170 1823, 158 1819, 188 1820, 180 0.0401 0.0387 0.3 0.5228 1.04 0.965 1.12 -0.0739 0.115 0.52 0.284 0.929 0.741 1.16 0.109 0.111 0.327 0.486 1.11 0.897 1.38 0.0539 0.112 0.629 0.2011 1.06 0.848 1.31 PRS_PLINK_1.99526231496888e.06 333 Extrapyramidal disease and abnormal movement disorders Both 563 6369 6 neurological darkblue 6369, 563 1591, 157 1600, 127 1604, 125 1572, 154 0.0642 0.0432 0.137 0.8636 1.07 0.98 1.16 -0.226 0.124 0.0678 1.169 0.797 0.625 1.02 -0.235 0.124 0.0584 1.233 0.79 0.619 1.01 -5.47e-05 0.118 1 0.0001599 1 0.793 1.26 PRS_PLINK_1.99526231496888e.06 333.1 Essential tremor Both 119 1443 6 neurological darkblue 1443, 119 361, 25 362, 31 359, 28 361, 35 0.157 0.0909 0.0845 1.073 1.17 0.979 1.4 0.219 0.272 0.421 0.3753 1.24 0.73 2.12 0.084 0.279 0.763 0.1174 1.09 0.63 1.88 0.329 0.267 0.218 0.6614 1.39 0.823 2.35 PRS_PLINK_1.99526231496888e.06 333.2 Myoclonus Both 65 700 6 neurological darkblue 700, 65 175, 19 175, 12 177, 17 173, 17 0.0855 0.129 0.506 0.2959 1.09 0.847 1.4 -0.599 0.376 0.112 0.9513 0.55 0.263 1.15 -0.0722 0.343 0.833 0.07926 0.93 0.475 1.82 -0.105 0.34 0.758 0.1203 0.901 0.463 1.75 PRS_PLINK_1.99526231496888e.06 333.4 Torsion dystonia Both 169 1872 6 neurological darkblue 1872, 169 471, 49 466, 50 470, 33 464, 37 -0.0904 0.0827 0.274 0.5617 0.914 0.777 1.07 0.0262 0.209 0.9 0.04581 1.03 0.682 1.54 -0.377 0.23 0.101 0.9942 0.686 0.436 1.08 -0.274 0.224 0.223 0.6526 0.761 0.49 1.18 PRS_PLINK_1.99526231496888e.06 334 Degenerative disease of the spinal cord Both 1142 12828 6 neurological darkblue 12828, 1142 3262, 306 3153, 265 3212, 283 3195, 287 0.00809 0.0312 0.795 0.09952 1.01 0.948 1.07 -0.106 0.0874 0.224 0.6504 0.899 0.758 1.07 -0.0619 0.086 0.472 0.3263 0.94 0.794 1.11 -0.0348 0.0859 0.685 0.1642 0.966 0.816 1.14 PRS_PLINK_1.99526231496888e.06 334.1 Spinocerebellar disease Both 65 836 6 neurological darkblue 836, 65 212, 15 206, 14 209, 16 209, 20 0.14 0.125 0.264 0.578 1.15 0.9 1.47 0.0465 0.369 0.9 0.04587 1.05 0.508 2.16 0.0648 0.358 0.856 0.06734 1.07 0.529 2.15 0.347 0.344 0.313 0.5044 1.42 0.721 2.78 PRS_PLINK_1.99526231496888e.06 334.2 Anterior horn cell disease Both 159 1626 6 neurological darkblue 1626, 159 408, 36 405, 34 405, 40 407, 49 0.134 0.0817 0.102 0.9923 1.14 0.974 1.34 -0.0678 0.245 0.782 0.1066 0.934 0.578 1.51 0.132 0.238 0.58 0.2369 1.14 0.715 1.82 0.336 0.23 0.144 0.8414 1.4 0.892 2.2 PRS_PLINK_1.99526231496888e.06 335 Multiple sclerosis Both 1001 10396 6 neurological darkblue 10396, 1001 2599, 267 2607, 251 2604, 243 2584, 240 -0.00548 0.0335 0.87 0.06041 0.995 0.931 1.06 -0.0641 0.0919 0.485 0.3138 0.938 0.783 1.12 -0.0986 0.0927 0.288 0.5411 0.906 0.756 1.09 -0.102 0.0931 0.274 0.5625 0.903 0.752 1.08 PRS_PLINK_1.99526231496888e.06 337 Disorders of the autonomic nervous system Both 157 1874 6 neurological darkblue 1874, 157 471, 40 465, 36 477, 38 460, 43 0.0565 0.0807 0.483 0.3157 1.06 0.903 1.24 -0.0973 0.235 0.679 0.1681 0.907 0.572 1.44 -0.0786 0.232 0.735 0.1339 0.924 0.587 1.46 0.103 0.228 0.65 0.1873 1.11 0.71 1.73 PRS_PLINK_1.99526231496888e.06 337.1 Peripheral autonomic neuropathy Both 36 467 6 neurological darkblue 467, 36 117, 9 117, 11 116, 9 117, 7 -0.0828 0.17 0.626 0.2032 0.921 0.66 1.28 0.19 0.442 0.668 0.1754 1.21 0.508 2.88 -0.0898 0.462 0.846 0.07269 0.914 0.37 2.26 -0.197 0.488 0.687 0.1633 0.821 0.315 2.14 PRS_PLINK_1.99526231496888e.06 338 Pain Both 465 5734 6 neurological darkblue 5734, 465 1438, 104 1429, 106 1445, 127 1421, 128 0.0978 0.0475 0.0394 1.404 1.1 1 1.21 0.0267 0.142 0.851 0.07019 1.03 0.778 1.36 0.194 0.136 0.154 0.8111 1.21 0.929 1.59 0.218 0.136 0.11 0.9581 1.24 0.952 1.62 PRS_PLINK_1.99526231496888e.06 338.1 Acute pain Both 226 2898 6 neurological darkblue 2898, 226 736, 47 712, 54 726, 65 723, 60 0.113 0.0672 0.0925 1.034 1.12 0.982 1.28 0.193 0.204 0.344 0.4639 1.21 0.813 1.81 0.36 0.196 0.0671 1.173 1.43 0.975 2.11 0.264 0.199 0.184 0.7361 1.3 0.882 1.92 PRS_PLINK_1.99526231496888e.06 338.2 Chronic pain Both 242 2934 6 neurological darkblue 2934, 242 740, 57 727, 55 741, 61 726, 69 0.0658 0.0658 0.317 0.4992 1.07 0.939 1.21 -0.0257 0.194 0.895 0.04837 0.975 0.667 1.42 0.0506 0.19 0.79 0.1025 1.05 0.725 1.53 0.205 0.185 0.267 0.5741 1.23 0.855 1.76 PRS_PLINK_1.99526231496888e.06 339 Other headache syndromes Both 5457 59083 6 neurological darkblue 59083, 5457 14880, 1347 14766, 1362 14666, 1368 14755, 1380 0.0187 0.0141 0.185 0.7324 1.02 0.991 1.05 0.019 0.0401 0.637 0.1961 1.02 0.942 1.1 0.031 0.0401 0.439 0.3571 1.03 0.954 1.12 0.0344 0.0401 0.39 0.4089 1.04 0.957 1.12 PRS_PLINK_1.99526231496888e.06 340 Migraine Both 2104 22427 6 neurological darkblue 22427, 2104 5655, 544 5566, 525 5628, 519 5573, 516 -0.0178 0.0233 0.443 0.3535 0.982 0.939 1.03 -0.0164 0.064 0.798 0.0979 0.984 0.868 1.12 -0.0369 0.0642 0.565 0.2479 0.964 0.85 1.09 -0.0396 0.0643 0.537 0.2697 0.961 0.847 1.09 PRS_PLINK_1.99526231496888e.06 340.1 Migrain with aura Both 154 1692 6 neurological darkblue 1692, 154 425, 42 421, 43 427, 37 419, 32 -0.0812 0.0858 0.344 0.4639 0.922 0.779 1.09 0.0903 0.226 0.689 0.1616 1.09 0.703 1.7 -0.136 0.232 0.557 0.2542 0.872 0.553 1.38 -0.245 0.242 0.311 0.5067 0.783 0.488 1.26 PRS_PLINK_1.99526231496888e.06 341 Other demyelinating diseases of central nervous system Both 196 1993 6 neurological darkblue 1993, 196 514, 46 485, 53 499, 53 494, 44 -0.0212 0.0762 0.781 0.1072 0.979 0.843 1.14 0.201 0.208 0.335 0.4756 1.22 0.813 1.84 0.171 0.209 0.411 0.386 1.19 0.789 1.79 -0.0109 0.217 0.96 0.01774 0.989 0.647 1.51 PRS_PLINK_1.99526231496888e.06 342 Hemiplegia Both 811 10529 6 neurological darkblue 10529, 811 2638, 209 2626, 183 2632, 195 2630, 224 0.0534 0.0358 0.136 0.8651 1.05 0.983 1.13 -0.129 0.105 0.216 0.6658 0.879 0.716 1.08 -0.0702 0.103 0.496 0.3048 0.932 0.762 1.14 0.0857 0.0999 0.391 0.4075 1.09 0.896 1.33 PRS_PLINK_1.99526231496888e.06 343 Infantile cerebral palsy Both 101 1092 6 neurological darkblue 1092, 101 281, 28 265, 31 274, 19 272, 23 -0.189 0.107 0.0782 1.107 0.828 0.671 1.02 0.135 0.269 0.617 0.2095 1.14 0.675 1.94 -0.348 0.301 0.246 0.6084 0.706 0.392 1.27 -0.152 0.289 0.598 0.2231 0.859 0.487 1.51 PRS_PLINK_1.99526231496888e.06 344 Other paralytic syndromes Both 415 4841 6 neurological darkblue 4841, 415 1222, 94 1205, 100 1205, 116 1207, 105 0.0651 0.0502 0.194 0.7111 1.07 0.967 1.18 0.0765 0.148 0.606 0.2175 1.08 0.807 1.44 0.222 0.144 0.123 0.9107 1.25 0.942 1.65 0.131 0.147 0.372 0.4295 1.14 0.855 1.52 PRS_PLINK_1.99526231496888e.06 345 Epilepsy, recurrent seizures, convulsions Both 3449 36984 6 neurological darkblue 36984, 3449 9301, 899 9215, 848 9336, 871 9127, 831 0.000828 0.0178 0.963 0.01643 1 0.967 1.04 -0.0501 0.05 0.317 0.4992 0.951 0.862 1.05 -0.036 0.0497 0.469 0.3289 0.965 0.875 1.06 -0.0623 0.0504 0.216 0.6655 0.94 0.851 1.04 PRS_PLINK_1.99526231496888e.06 345.1 Epilepsy Both 600 6422 6 neurological darkblue 6422, 600 1613, 152 1605, 142 1620, 168 1583, 138 -0.0169 0.0432 0.696 0.1573 0.983 0.903 1.07 -0.068 0.121 0.576 0.2399 0.934 0.736 1.19 0.0889 0.117 0.447 0.3495 1.09 0.869 1.37 -0.0758 0.122 0.536 0.2709 0.927 0.729 1.18 PRS_PLINK_1.99526231496888e.06 345.11 Generalized convulsive epilepsy Both 313 3237 6 neurological darkblue 3237, 313 810, 69 807, 76 813, 94 805, 74 0.0412 0.0582 0.479 0.3199 1.04 0.93 1.17 0.0961 0.172 0.576 0.2392 1.1 0.786 1.54 0.287 0.165 0.0829 1.081 1.33 0.963 1.84 0.0647 0.173 0.709 0.1496 1.07 0.76 1.5 PRS_PLINK_1.99526231496888e.06 345.12 Partial epilepsy Both 200 2113 6 neurological darkblue 2113, 200 529, 55 535, 42 530, 52 519, 51 -0.0123 0.0742 0.869 0.06115 0.988 0.854 1.14 -0.29 0.211 0.169 0.7713 0.748 0.495 1.13 -0.0668 0.201 0.739 0.1311 0.935 0.631 1.39 -0.0447 0.203 0.825 0.08343 0.956 0.643 1.42 PRS_PLINK_1.99526231496888e.06 345.3 Convulsions Both 1513 16471 6 neurological darkblue 16471, 1513 4123, 403 4119, 365 4118, 390 4111, 355 -0.0136 0.0268 0.612 0.2135 0.987 0.936 1.04 -0.103 0.0755 0.173 0.7617 0.902 0.778 1.05 -0.0318 0.0743 0.668 0.1751 0.969 0.837 1.12 -0.126 0.0761 0.097 1.013 0.881 0.759 1.02 PRS_PLINK_1.99526231496888e.06 346.1 Nonspecific abnormal findings on radiological and other examination of skull and head Both 91 1064 6 neurological darkblue 1064, 91 272, 28 260, 15 267, 23 265, 25 0.05 0.105 0.633 0.1985 1.05 0.856 1.29 -0.573 0.32 0.0734 1.134 0.564 0.301 1.06 -0.145 0.289 0.616 0.2108 0.865 0.491 1.52 -0.0755 0.281 0.788 0.1033 0.927 0.534 1.61 PRS_PLINK_1.99526231496888e.06 348 Other conditions of brain Both 469 5731 6 neurological darkblue 5731, 469 1443, 110 1431, 114 1433, 112 1421, 133 0.0425 0.0475 0.371 0.4306 1.04 0.951 1.15 0.0414 0.138 0.764 0.117 1.04 0.795 1.37 0.017 0.138 0.902 0.04476 1.02 0.775 1.33 0.2 0.133 0.133 0.8755 1.22 0.941 1.59 PRS_PLINK_1.99526231496888e.06 348.2 Cerebral edema and compression of brain Both 159 2021 6 neurological darkblue 2021, 159 510, 30 501, 46 507, 37 502, 46 0.0569 0.0804 0.479 0.3198 1.06 0.904 1.24 0.442 0.238 0.0632 1.199 1.56 0.976 2.48 0.237 0.249 0.342 0.4665 1.27 0.778 2.06 0.429 0.238 0.0714 1.146 1.54 0.963 2.45 PRS_PLINK_1.99526231496888e.06 348.4 Cerebral cysts Both 97 1023 6 neurological darkblue 1023, 97 259, 25 253, 20 255, 21 256, 31 0.117 0.105 0.262 0.5813 1.12 0.916 1.38 -0.205 0.306 0.502 0.2989 0.814 0.447 1.48 -0.129 0.303 0.669 0.1747 0.879 0.485 1.59 0.195 0.279 0.485 0.3146 1.22 0.704 2.1 PRS_PLINK_1.99526231496888e.06 348.7 Coma Both 244 2540 6 neurological darkblue 2540, 244 634, 49 635, 67 637, 64 633, 64 0.0473 0.0645 0.463 0.3343 1.05 0.924 1.19 0.306 0.194 0.115 0.9411 1.36 0.929 1.99 0.272 0.196 0.165 0.7836 1.31 0.894 1.93 0.271 0.196 0.166 0.7793 1.31 0.894 1.92 PRS_PLINK_1.99526231496888e.06 348.8 Encephalopathy, not elsewhere classified Both 147 1803 6 neurological darkblue 1803, 147 451, 37 455, 33 446, 36 450, 41 0.0236 0.0855 0.782 0.1067 1.02 0.866 1.21 -0.131 0.244 0.592 0.2274 0.877 0.544 1.42 -0.0509 0.241 0.833 0.07954 0.95 0.593 1.52 0.0875 0.232 0.706 0.1509 1.09 0.692 1.72 PRS_PLINK_1.99526231496888e.06 348.9 Other conditions of brain, NOS Both 266 2780 6 neurological darkblue 2780, 266 692, 78 695, 64 695, 64 695, 60 -0.069 0.0644 0.284 0.5468 0.933 0.823 1.06 -0.212 0.175 0.228 0.6421 0.809 0.574 1.14 -0.193 0.176 0.273 0.5644 0.825 0.585 1.16 -0.259 0.178 0.146 0.8368 0.772 0.544 1.09 PRS_PLINK_1.99526231496888e.06 349 Other and unspecified disorders of the nervous system Both 221 2482 6 neurological darkblue 2482, 221 621, 50 625, 56 620, 55 616, 60 0.0514 0.0676 0.447 0.3498 1.05 0.922 1.2 0.104 0.2 0.602 0.2203 1.11 0.75 1.64 0.0845 0.201 0.674 0.1711 1.09 0.734 1.61 0.196 0.197 0.321 0.4938 1.22 0.826 1.79 PRS_PLINK_1.99526231496888e.06 350 Abnormal movement Both 1558 18808 6 neurological darkblue 18808, 1558 4709, 365 4713, 383 4720, 402 4662, 408 0.0589 0.0258 0.0227 1.644 1.06 1.01 1.12 0.05 0.0759 0.51 0.2921 1.05 0.906 1.22 0.0982 0.0751 0.191 0.7192 1.1 0.952 1.28 0.131 0.075 0.0799 1.098 1.14 0.984 1.32 PRS_PLINK_1.99526231496888e.06 350.1 Abnormal involuntary movements Both 540 6480 6 neurological darkblue 6480, 540 1620, 125 1617, 147 1634, 130 1606, 138 0.0485 0.0441 0.271 0.5664 1.05 0.963 1.14 0.167 0.126 0.186 0.7303 1.18 0.923 1.51 0.0437 0.129 0.736 0.1334 1.04 0.811 1.35 0.132 0.128 0.304 0.5165 1.14 0.887 1.47 PRS_PLINK_1.99526231496888e.06 350.2 Abnormality of gait Both 884 10945 6 neurological darkblue 10945, 884 2749, 203 2732, 214 2733, 242 2731, 225 0.0499 0.0342 0.145 0.8393 1.05 0.983 1.12 0.0606 0.101 0.55 0.2596 1.06 0.871 1.3 0.182 0.0987 0.0657 1.182 1.2 0.988 1.45 0.112 0.1 0.262 0.5812 1.12 0.919 1.36 PRS_PLINK_1.99526231496888e.06 350.3 Lack of coordination Both 223 2634 6 neurological darkblue 2634, 223 667, 61 650, 44 658, 47 659, 71 0.0923 0.0672 0.17 0.7697 1.1 0.961 1.25 -0.295 0.203 0.146 0.8346 0.744 0.5 1.11 -0.218 0.2 0.277 0.5576 0.804 0.544 1.19 0.169 0.182 0.351 0.4545 1.18 0.83 1.69 PRS_PLINK_1.99526231496888e.06 350.6 Disturbances of sensation of smell and taste Both 39 397 6 neurological darkblue 397, 39 100, 9 100, 8 98, 14 99, 8 -0.0272 0.163 0.868 0.06171 0.973 0.707 1.34 -0.0222 0.478 0.963 0.01637 0.978 0.383 2.49 0.527 0.438 0.229 0.641 1.69 0.718 3.99 -0.11 0.478 0.817 0.08769 0.895 0.351 2.28 PRS_PLINK_1.99526231496888e.06 351 Other peripheral nerve disorders Both 8509 92624 6 neurological darkblue 92624, 8509 23161, 2111 23301, 2147 22994, 2105 23143, 2143 0.00236 0.0114 0.835 0.0782 1 0.98 1.02 0.0106 0.032 0.741 0.1301 1.01 0.949 1.08 0.00271 0.0322 0.933 0.03016 1 0.941 1.07 0.0175 0.0321 0.586 0.2323 1.02 0.956 1.08 PRS_PLINK_1.99526231496888e.06 352 Disorders of other cranial nerves Both 903 9985 6 neurological darkblue 9985, 903 2499, 208 2495, 238 2494, 227 2495, 230 0.0441 0.0344 0.2 0.6991 1.05 0.977 1.12 0.131 0.0988 0.184 0.7359 1.14 0.94 1.38 0.0876 0.0997 0.38 0.4204 1.09 0.898 1.33 0.107 0.0995 0.282 0.5497 1.11 0.916 1.35 PRS_PLINK_1.99526231496888e.06 352.1 Trigeminal nerve disorders [CN5] Both 319 3438 6 neurological darkblue 3438, 319 873, 86 846, 81 862, 78 857, 74 -0.000151 0.0584 0.998 0.0008979 1 0.892 1.12 -0.0428 0.161 0.791 0.1019 0.958 0.698 1.31 -0.086 0.162 0.596 0.2246 0.918 0.667 1.26 -0.152 0.165 0.357 0.4468 0.859 0.621 1.19 PRS_PLINK_1.99526231496888e.06 352.2 Facial nerve disorders [CN7] Both 565 6376 6 neurological darkblue 6376, 565 1593, 123 1599, 156 1599, 141 1583, 145 0.0242 0.0438 0.58 0.2362 1.02 0.94 1.12 0.231 0.125 0.0646 1.19 1.26 0.986 1.61 0.131 0.128 0.303 0.5182 1.14 0.888 1.46 0.172 0.127 0.175 0.7576 1.19 0.926 1.52 PRS_PLINK_1.99526231496888e.06 353 Nerve root and plexus disorders Both 692 8200 6 neurological darkblue 8200, 692 2073, 158 2028, 189 2080, 172 2013, 173 0.0372 0.0393 0.344 0.4631 1.04 0.961 1.12 0.197 0.112 0.0777 1.11 1.22 0.978 1.52 0.0828 0.114 0.468 0.3301 1.09 0.869 1.36 0.12 0.114 0.291 0.5366 1.13 0.902 1.41 PRS_PLINK_1.99526231496888e.06 353.1 Nerve plexus lesions Both 79 883 6 neurological darkblue 883, 79 232, 22 208, 20 220, 21 221, 16 -0.0791 0.119 0.505 0.297 0.924 0.732 1.17 0.0157 0.316 0.96 0.01758 1.02 0.547 1.89 0.0228 0.311 0.942 0.02616 1.02 0.557 1.88 -0.271 0.331 0.413 0.3835 0.763 0.399 1.46 PRS_PLINK_1.99526231496888e.06 353.2 Nerve root lesions Both 36 413 6 neurological darkblue 413, 36 103, 7 104, 10 102, 10 103, 9 0.134 0.161 0.405 0.3929 1.14 0.834 1.57 0.21 0.485 0.665 0.1769 1.23 0.476 3.19 0.382 0.482 0.428 0.369 1.47 0.57 3.77 0.453 0.513 0.377 0.4235 1.57 0.576 4.3 PRS_PLINK_1.99526231496888e.06 356 Hereditary and idiopathic peripheral neuropathy Both 93 1075 6 neurological darkblue 1075, 93 274, 22 267, 21 266, 18 268, 32 0.192 0.0995 0.0539 1.269 1.21 0.997 1.47 0.012 0.308 0.969 0.01375 1.01 0.553 1.85 -0.181 0.321 0.573 0.2422 0.834 0.444 1.57 0.386 0.284 0.174 0.7594 1.47 0.843 2.57 PRS_PLINK_1.99526231496888e.06 357 Inflammatory and toxic neuropathy Both 759 9463 6 neurological darkblue 9463, 759 2366, 158 2388, 163 2340, 198 2366, 239 0.159 0.0363 1.19e-05 4.926 1.17 1.09 1.26 0.0213 0.115 0.853 0.06904 1.02 0.816 1.28 0.239 0.11 0.0303 1.519 1.27 1.02 1.58 0.41 0.106 0.000112 3.951 1.51 1.22 1.86 PRS_PLINK_1.99526231496888e.06 358 Myoneural disorders Both 113 1447 6 neurological darkblue 1447, 113 363, 33 365, 18 358, 31 361, 31 0.0284 0.0948 0.765 0.1166 1.03 0.854 1.24 -0.586 0.294 0.0463 1.335 0.556 0.313 0.99 -0.0432 0.256 0.866 0.06238 0.958 0.58 1.58 -0.032 0.255 0.9 0.04564 0.968 0.587 1.6 PRS_PLINK_1.99526231496888e.06 358.1 Myasthenia gravis Both 105 1336 6 neurological darkblue 1336, 105 336, 31 332, 15 334, 31 334, 28 0.0538 0.0984 0.585 0.2331 1.06 0.87 1.28 -0.683 0.313 0.0291 1.536 0.505 0.273 0.933 -0.000218 0.26 0.999 0.0002897 1 0.6 1.66 -0.0792 0.265 0.765 0.1162 0.924 0.549 1.55 PRS_PLINK_1.99526231496888e.06 359 Muscular dystrophies and other myopathies Both 245 3358 6 neurological darkblue 3358, 245 852, 50 830, 43 846, 88 830, 63 0.124 0.0638 0.0516 1.288 1.13 0.999 1.28 -0.0974 0.211 0.644 0.1911 0.907 0.6 1.37 0.549 0.182 0.00257 2.59 1.73 1.21 2.48 0.253 0.194 0.191 0.7179 1.29 0.881 1.88 PRS_PLINK_1.99526231496888e.06 359.1 Muscular dystrophies Both 61 888 6 neurological darkblue 888, 61 223, 12 222, 13 224, 26 219, 10 0.00831 0.128 0.948 0.02314 1.01 0.785 1.29 0.103 0.389 0.791 0.1019 1.11 0.517 2.37 0.74 0.35 0.0346 1.461 2.1 1.06 4.16 -0.171 0.415 0.679 0.1679 0.843 0.374 1.9 PRS_PLINK_1.99526231496888e.06 359.2 Myopathy Both 190 2586 6 neurological darkblue 2586, 190 649, 40 649, 32 641, 62 647, 55 0.166 0.0718 0.0209 1.679 1.18 1.03 1.36 -0.198 0.238 0.407 0.3904 0.821 0.514 1.31 0.423 0.207 0.0416 1.38 1.53 1.02 2.29 0.309 0.212 0.146 0.8366 1.36 0.898 2.06 PRS_PLINK_1.99526231496888e.06 360 Disorders of the globe Both 226 2287 7 sense organs darkseagreen4 2287, 226 573, 65 571, 55 575, 55 568, 51 -0.0609 0.071 0.391 0.4076 0.941 0.819 1.08 -0.168 0.192 0.382 0.4181 0.846 0.581 1.23 -0.188 0.191 0.326 0.4864 0.829 0.57 1.21 -0.247 0.195 0.205 0.6891 0.781 0.533 1.14 PRS_PLINK_1.99526231496888e.06 360.2 Progressive myopia Both 167 1721 7 sense organs darkseagreen4 1721, 167 431, 42 435, 46 431, 38 424, 41 -0.00819 0.0809 0.919 0.03651 0.992 0.846 1.16 0.0623 0.221 0.778 0.1088 1.06 0.69 1.64 -0.114 0.231 0.62 0.2073 0.892 0.567 1.4 -0.00606 0.227 0.979 0.009364 0.994 0.637 1.55 PRS_PLINK_1.99526231496888e.06 361 Retinal detachments and defects Both 2307 22703 7 sense organs darkseagreen4 22703, 2307 5688, 549 5697, 593 5640, 585 5667, 579 0.0224 0.0217 0.303 0.5185 1.02 0.98 1.07 0.0764 0.0621 0.219 0.6604 1.08 0.956 1.22 0.0686 0.0623 0.27 0.5681 1.07 0.948 1.21 0.0528 0.0625 0.398 0.3999 1.05 0.933 1.19 PRS_PLINK_1.99526231496888e.06 361.1 Retinal detachment with retinal defect Both 980 9779 7 sense organs darkseagreen4 9779, 980 2454, 228 2446, 261 2445, 245 2428, 246 0.0174 0.0335 0.604 0.2189 1.02 0.953 1.09 0.138 0.0949 0.146 0.837 1.15 0.953 1.38 0.069 0.0961 0.473 0.3251 1.07 0.887 1.29 0.0848 0.0961 0.378 0.4227 1.09 0.902 1.31 PRS_PLINK_1.99526231496888e.06 361.2 Retinoschisis and retinal cysts Both 40 490 7 sense organs darkseagreen4 490, 40 123, 11 124, 10 121, 14 121, 5 -0.13 0.166 0.436 0.3609 0.878 0.634 1.22 -0.102 0.43 0.811 0.09072 0.903 0.389 2.09 0.294 0.405 0.469 0.3292 1.34 0.606 2.97 -0.786 0.51 0.123 0.9094 0.456 0.168 1.24 PRS_PLINK_1.99526231496888e.06 362 Other retinal disorders Both 2379 25973 7 sense organs darkseagreen4 25973, 2379 6507, 576 6520, 575 6447, 576 6489, 651 0.0404 0.021 0.0545 1.263 1.04 0.999 1.08 -0.00449 0.0614 0.942 0.02609 0.996 0.883 1.12 0.00765 0.0614 0.901 0.0453 1.01 0.893 1.14 0.122 0.0598 0.0416 1.381 1.13 1 1.27 PRS_PLINK_1.99526231496888e.06 362.2 Degeneration of macula and posterior pole of retina Both 1374 14566 7 sense organs darkseagreen4 14566, 1374 3645, 323 3633, 339 3649, 326 3632, 385 0.0525 0.0274 0.0552 1.258 1.05 0.999 1.11 0.0515 0.081 0.525 0.2796 1.05 0.898 1.23 0.00606 0.0818 0.941 0.02646 1.01 0.857 1.18 0.178 0.0789 0.0238 1.623 1.2 1.02 1.4 PRS_PLINK_1.99526231496888e.06 362.29 Macular degeneration (senile) of retina NOS Both 1372 14540 7 sense organs darkseagreen4 14540, 1372 3643, 323 3632, 339 3635, 326 3623, 383 0.0519 0.0274 0.0582 1.235 1.05 0.998 1.11 0.0513 0.081 0.526 0.2787 1.05 0.898 1.23 0.00933 0.0818 0.909 0.04135 1.01 0.86 1.18 0.175 0.079 0.0264 1.578 1.19 1.02 1.39 PRS_PLINK_1.99526231496888e.06 362.3 Other nondiabetic retinopathy Both 106 1132 7 sense organs darkseagreen4 1132, 106 285, 25 288, 19 277, 30 282, 32 0.114 0.0976 0.245 0.6114 1.12 0.925 1.36 -0.307 0.306 0.316 0.5006 0.735 0.404 1.34 0.179 0.279 0.52 0.2839 1.2 0.693 2.07 0.269 0.276 0.33 0.4819 1.31 0.762 2.24 PRS_PLINK_1.99526231496888e.06 362.31 Separation of retinal layers Both 76 683 7 sense organs darkseagreen4 683, 76 171, 19 172, 15 169, 20 171, 22 0.0855 0.118 0.47 0.3277 1.09 0.864 1.37 -0.25 0.35 0.474 0.3241 0.779 0.392 1.55 0.0518 0.33 0.875 0.05789 1.05 0.551 2.01 0.101 0.324 0.755 0.122 1.11 0.586 2.09 PRS_PLINK_1.99526231496888e.06 362.4 Retinal vascular changes and abnomalities Both 475 5694 7 sense organs darkseagreen4 5694, 475 1440, 106 1409, 116 1429, 118 1414, 135 0.097 0.0466 0.0373 1.428 1.1 1.01 1.21 0.114 0.139 0.412 0.3852 1.12 0.854 1.47 0.112 0.138 0.417 0.3796 1.12 0.853 1.47 0.248 0.134 0.0649 1.188 1.28 0.985 1.67 PRS_PLINK_1.99526231496888e.06 362.6 Peripheral retinal degenerations Both 126 1302 7 sense organs darkseagreen4 1302, 126 331, 31 319, 36 325, 30 326, 29 -0.0661 0.0928 0.476 0.3222 0.936 0.78 1.12 0.197 0.254 0.438 0.3589 1.22 0.741 2 -0.0153 0.263 0.954 0.02063 0.985 0.588 1.65 -0.0598 0.264 0.821 0.08589 0.942 0.562 1.58 PRS_PLINK_1.99526231496888e.06 362.7 Hereditary retinal dystrophies Both 61 584 7 sense organs darkseagreen4 584, 61 147, 21 145, 19 146, 10 146, 11 -0.297 0.145 0.0406 1.392 0.743 0.559 0.987 -0.0858 0.332 0.796 0.09897 0.918 0.479 1.76 -0.798 0.395 0.0435 1.362 0.45 0.208 0.977 -0.726 0.383 0.0581 1.236 0.484 0.228 1.03 PRS_PLINK_1.99526231496888e.06 362.8 Retinal hemorrhage/ischemia Both 79 801 7 sense organs darkseagreen4 801, 79 202, 21 198, 20 200, 19 200, 19 -0.0631 0.115 0.582 0.2352 0.939 0.75 1.18 0.00252 0.322 0.994 0.002725 1 0.534 1.88 -0.0864 0.322 0.788 0.1033 0.917 0.488 1.72 -0.145 0.325 0.655 0.1839 0.865 0.457 1.64 PRS_PLINK_1.99526231496888e.06 363 Chorioretinal inflammations, scars, and other disorders of choroid Both 104 1221 7 sense organs darkseagreen4 1221, 104 309, 26 302, 27 306, 29 304, 22 0.0099 0.102 0.923 0.03496 1.01 0.827 1.23 0.087 0.28 0.756 0.1213 1.09 0.63 1.89 0.154 0.276 0.578 0.2383 1.17 0.679 2 -0.121 0.292 0.679 0.1679 0.886 0.5 1.57 PRS_PLINK_1.99526231496888e.06 363.3 Chorioretinal scars Both 34 506 7 sense organs darkseagreen4 506, 34 127, 7 127, 8 127, 10 125, 9 0.137 0.165 0.406 0.3917 1.15 0.83 1.58 0.202 0.502 0.687 0.1628 1.22 0.457 3.27 0.368 0.471 0.435 0.3617 1.44 0.574 3.64 0.325 0.487 0.504 0.2974 1.38 0.533 3.6 PRS_PLINK_1.99526231496888e.06 364 Corneal opacity and other disorders of cornea Both 440 4556 7 sense organs darkseagreen4 4556, 440 1151, 105 1133, 124 1145, 110 1127, 101 -0.00931 0.0499 0.852 0.06954 0.991 0.898 1.09 0.176 0.139 0.205 0.6882 1.19 0.909 1.56 0.0513 0.142 0.718 0.144 1.05 0.797 1.39 -0.0259 0.145 0.859 0.06621 0.974 0.733 1.3 PRS_PLINK_1.99526231496888e.06 364.1 Corneal opacity Both 58 650 7 sense organs darkseagreen4 650, 58 163, 11 159, 17 162, 12 163, 18 0.0633 0.133 0.633 0.1984 1.07 0.821 1.38 0.509 0.391 0.194 0.713 1.66 0.772 3.58 0.0437 0.414 0.916 0.03818 1.04 0.464 2.35 0.465 0.383 0.224 0.6491 1.59 0.752 3.37 PRS_PLINK_1.99526231496888e.06 364.2 Corneal edema Both 43 547 7 sense organs darkseagreen4 547, 43 137, 9 137, 11 138, 14 135, 9 0.0351 0.158 0.824 0.08388 1.04 0.759 1.41 0.0825 0.443 0.852 0.06941 1.09 0.456 2.59 0.343 0.43 0.425 0.372 1.41 0.607 3.27 -0.0252 0.479 0.958 0.01862 0.975 0.382 2.49 PRS_PLINK_1.99526231496888e.06 364.4 Corneal degenerations Both 149 1459 7 sense organs darkseagreen4 1459, 149 366, 27 367, 44 361, 37 365, 41 0.128 0.0843 0.13 0.8865 1.14 0.963 1.34 0.493 0.251 0.0496 1.304 1.64 1 2.68 0.324 0.259 0.21 0.6774 1.38 0.833 2.3 0.415 0.254 0.102 0.99 1.52 0.92 2.49 PRS_PLINK_1.99526231496888e.06 364.41 Keratoconus Both 66 667 7 sense organs darkseagreen4 667, 66 167, 14 169, 19 164, 15 167, 18 0.0613 0.124 0.62 0.2079 1.06 0.835 1.35 0.345 0.356 0.333 0.4781 1.41 0.702 2.84 0.141 0.376 0.708 0.1501 1.15 0.551 2.4 0.198 0.361 0.583 0.2343 1.22 0.601 2.47 PRS_PLINK_1.99526231496888e.06 364.5 Corneal dystrophy Both 136 1407 7 sense organs darkseagreen4 1407, 136 353, 34 351, 42 353, 35 350, 25 -0.0983 0.0923 0.287 0.5421 0.906 0.756 1.09 0.209 0.239 0.382 0.4181 1.23 0.771 1.97 0.0667 0.249 0.788 0.1032 1.07 0.657 1.74 -0.293 0.267 0.273 0.5635 0.746 0.442 1.26 PRS_PLINK_1.99526231496888e.06 364.9 Cornea replaced by transplant Both 69 706 7 sense organs darkseagreen4 706, 69 179, 17 175, 20 175, 15 177, 17 -0.0475 0.128 0.71 0.1484 0.954 0.742 1.23 0.149 0.336 0.657 0.1823 1.16 0.601 2.24 -0.111 0.358 0.757 0.1211 0.895 0.444 1.81 -0.028 0.348 0.936 0.02877 0.972 0.492 1.92 PRS_PLINK_1.99526231496888e.06 365 Glaucoma Both 2838 29671 7 sense organs darkseagreen4 29671, 2838 7404, 720 7421, 693 7418, 711 7414, 714 0.0129 0.0194 0.506 0.2962 1.01 0.975 1.05 -0.0407 0.0556 0.465 0.3327 0.96 0.861 1.07 -0.0144 0.0553 0.795 0.09973 0.986 0.884 1.1 -0.0104 0.0553 0.852 0.06978 0.99 0.888 1.1 PRS_PLINK_1.99526231496888e.06 365.1 Open-angle glaucoma Both 674 6777 7 sense organs darkseagreen4 6777, 674 1707, 176 1677, 152 1698, 176 1690, 170 0.00506 0.0396 0.898 0.04659 1.01 0.93 1.09 -0.128 0.116 0.267 0.573 0.88 0.701 1.1 -0.000887 0.112 0.994 0.002761 0.999 0.803 1.24 -0.0303 0.113 0.788 0.1033 0.97 0.778 1.21 PRS_PLINK_1.99526231496888e.06 365.11 Primary open angle glaucoma Both 670 6746 7 sense organs darkseagreen4 6746, 670 1695, 175 1671, 151 1693, 174 1680, 170 0.00988 0.0398 0.804 0.09486 1.01 0.934 1.09 -0.133 0.116 0.253 0.5976 0.876 0.698 1.1 -0.0114 0.112 0.919 0.03661 0.989 0.794 1.23 -0.0279 0.113 0.805 0.09445 0.972 0.779 1.21 PRS_PLINK_1.99526231496888e.06 365.2 Primary angle-closure glaucoma Both 477 4805 7 sense organs darkseagreen4 4805, 477 1203, 121 1210, 132 1195, 103 1196, 121 -0.0151 0.0476 0.752 0.1239 0.985 0.897 1.08 0.0846 0.132 0.521 0.2833 1.09 0.841 1.41 -0.154 0.139 0.269 0.57 0.857 0.652 1.13 0.00708 0.134 0.958 0.01867 1.01 0.774 1.31 PRS_PLINK_1.99526231496888e.06 366 Cataract Both 12277 115766 7 sense organs darkseagreen4 115766, 12277 28930, 2995 28931, 3101 29042, 3022 28822, 3153 0.00999 0.00942 0.289 0.5396 1.01 0.992 1.03 0.0305 0.027 0.259 0.5873 1.03 0.978 1.09 -0.00191 0.0271 0.944 0.02513 0.998 0.946 1.05 0.0403 0.0269 0.134 0.8716 1.04 0.988 1.1 PRS_PLINK_1.99526231496888e.06 366.1 Nonsenile Cataract Both 42 517 7 sense organs darkseagreen4 517, 42 131, 13 128, 11 129, 10 129, 8 -0.0994 0.158 0.528 0.2772 0.905 0.665 1.23 -0.109 0.415 0.792 0.101 0.897 0.398 2.02 -0.251 0.419 0.549 0.2608 0.778 0.342 1.77 -0.429 0.439 0.328 0.4843 0.651 0.276 1.54 PRS_PLINK_1.99526231496888e.06 366.2 Senile cataract Both 5021 54573 7 sense organs darkseagreen4 54573, 5021 13792, 1283 13569, 1212 13546, 1196 13643, 1328 0.0145 0.0145 0.318 0.4975 1.01 0.986 1.04 -0.0411 0.0418 0.326 0.4868 0.96 0.884 1.04 -0.0521 0.042 0.214 0.6697 0.949 0.874 1.03 0.0457 0.041 0.265 0.5761 1.05 0.966 1.13 PRS_PLINK_1.99526231496888e.06 366.3 Traumatic cataract Both 69 681 7 sense organs darkseagreen4 681, 69 172, 12 171, 22 167, 15 170, 20 0.174 0.115 0.132 0.8792 1.19 0.949 1.49 0.646 0.362 0.0745 1.128 1.91 0.938 3.88 0.27 0.389 0.488 0.3119 1.31 0.611 2.81 0.434 0.369 0.239 0.6207 1.54 0.749 3.18 PRS_PLINK_1.99526231496888e.06 367 Disorders of refraction and accommodation; blindness and low vision Both 1610 16847 7 sense organs darkseagreen4 16847, 1610 4213, 392 4228, 438 4194, 373 4206, 407 -0.000551 0.0261 0.983 0.007382 0.999 0.95 1.05 0.106 0.0727 0.147 0.8338 1.11 0.964 1.28 -0.0478 0.0755 0.527 0.2784 0.953 0.822 1.11 0.0321 0.074 0.664 0.1779 1.03 0.893 1.19 PRS_PLINK_1.99526231496888e.06 367.1 Myopia Both 880 8778 7 sense organs darkseagreen4 8778, 880 2193, 212 2203, 236 2196, 206 2184, 226 0.0129 0.0351 0.714 0.1462 1.01 0.946 1.09 0.1 0.0991 0.311 0.5076 1.11 0.911 1.34 -0.0343 0.102 0.737 0.1326 0.966 0.791 1.18 0.0615 0.1 0.539 0.2684 1.06 0.874 1.29 PRS_PLINK_1.99526231496888e.06 367.2 Astigmatism Both 124 1340 7 sense organs darkseagreen4 1340, 124 338, 32 330, 36 339, 26 331, 30 -0.0395 0.094 0.675 0.1709 0.961 0.8 1.16 0.187 0.252 0.459 0.3378 1.21 0.735 1.98 -0.214 0.27 0.427 0.3693 0.807 0.476 1.37 -0.0806 0.262 0.758 0.1204 0.923 0.553 1.54 PRS_PLINK_1.99526231496888e.06 367.8 Hypermetropia Both 162 1737 7 sense organs darkseagreen4 1737, 162 434, 35 434, 46 437, 43 431, 38 0.00911 0.0818 0.911 0.04033 1.01 0.86 1.18 0.276 0.23 0.231 0.6373 1.32 0.839 2.07 0.19 0.234 0.417 0.3804 1.21 0.765 1.91 0.105 0.24 0.661 0.18 1.11 0.694 1.78 PRS_PLINK_1.99526231496888e.06 367.9 Blindness and low vision Both 439 4993 7 sense organs darkseagreen4 4993, 439 1248, 110 1255, 118 1246, 98 1242, 113 -0.00576 0.0501 0.908 0.04169 0.994 0.901 1.1 0.0562 0.138 0.683 0.1658 1.06 0.808 1.39 -0.124 0.144 0.388 0.4108 0.883 0.666 1.17 0.018 0.139 0.897 0.04706 1.02 0.775 1.34 PRS_PLINK_1.99526231496888e.06 368 Visual disturbances Both 1896 21389 7 sense organs darkseagreen4 21389, 1896 5373, 436 5331, 495 5353, 476 5327, 489 0.0493 0.0236 0.0362 1.442 1.05 1 1.1 0.137 0.0684 0.0455 1.342 1.15 1 1.31 0.0936 0.069 0.175 0.7571 1.1 0.959 1.26 0.126 0.0687 0.0661 1.18 1.13 0.992 1.3 PRS_PLINK_1.99526231496888e.06 368.1 Amblyopia Both 320 3683 7 sense organs darkseagreen4 3683, 320 928, 71 915, 93 920, 79 920, 77 0.0047 0.0581 0.936 0.02894 1 0.896 1.13 0.286 0.163 0.0794 1.1 1.33 0.967 1.83 0.124 0.169 0.463 0.3347 1.13 0.813 1.58 0.0952 0.169 0.574 0.241 1.1 0.789 1.53 PRS_PLINK_1.99526231496888e.06 368.2 Diplopia and disorders of binocular vision Both 454 5275 7 sense organs darkseagreen4 5275, 454 1319, 116 1328, 119 1311, 114 1317, 105 -0.00511 0.0487 0.916 0.03794 0.995 0.904 1.09 0.0216 0.135 0.873 0.05887 1.02 0.784 1.33 -0.00908 0.137 0.947 0.02358 0.991 0.758 1.3 -0.103 0.14 0.46 0.3375 0.902 0.685 1.19 PRS_PLINK_1.99526231496888e.06 368.3 Anisometropia Both 103 1123 7 sense organs darkseagreen4 1123, 103 287, 27 277, 23 281, 20 277, 33 0.0929 0.0978 0.342 0.4658 1.1 0.906 1.33 -0.139 0.29 0.631 0.1998 0.87 0.492 1.54 -0.345 0.301 0.251 0.601 0.708 0.393 1.28 0.182 0.268 0.496 0.3041 1.2 0.709 2.03 PRS_PLINK_1.99526231496888e.06 368.4 Visual field defects Both 209 2315 7 sense organs darkseagreen4 2315, 209 578, 45 582, 46 577, 55 577, 63 0.0922 0.0692 0.183 0.7377 1.1 0.957 1.26 0.0376 0.215 0.861 0.06476 1.04 0.681 1.58 0.21 0.207 0.309 0.5098 1.23 0.823 1.85 0.337 0.202 0.0943 1.025 1.4 0.944 2.08 PRS_PLINK_1.99526231496888e.06 368.9 Subjective visual disturbances Both 395 4538 7 sense organs darkseagreen4 4538, 395 1141, 74 1133, 108 1128, 101 1135, 112 0.138 0.0504 0.00627 2.203 1.15 1.04 1.27 0.38 0.155 0.0144 1.842 1.46 1.08 1.98 0.317 0.157 0.0444 1.353 1.37 1.01 1.87 0.432 0.155 0.00521 2.283 1.54 1.14 2.09 PRS_PLINK_1.99526231496888e.06 369 Infection of the eye Both 353 4013 7 sense organs darkseagreen4 4013, 353 1005, 89 1004, 77 1002, 82 1002, 105 0.0716 0.0554 0.196 0.7074 1.07 0.964 1.2 -0.144 0.161 0.371 0.4311 0.866 0.632 1.19 -0.0697 0.158 0.66 0.1807 0.933 0.684 1.27 0.169 0.15 0.26 0.5858 1.18 0.883 1.59 PRS_PLINK_1.99526231496888e.06 369.2 Eye infection, viral Both 72 887 7 sense organs darkseagreen4 887, 72 223, 20 221, 17 221, 18 222, 17 -0.0333 0.122 0.785 0.1053 0.967 0.762 1.23 -0.163 0.332 0.622 0.2061 0.849 0.443 1.63 -0.0933 0.328 0.776 0.1102 0.911 0.479 1.73 -0.167 0.333 0.616 0.2103 0.846 0.44 1.63 PRS_PLINK_1.99526231496888e.06 369.5 Conjunctivitis, infectious Both 131 1554 7 sense organs darkseagreen4 1554, 131 389, 33 388, 30 392, 30 385, 38 0.0345 0.0898 0.701 0.1545 1.04 0.868 1.23 -0.0751 0.258 0.772 0.1126 0.928 0.559 1.54 -0.0438 0.258 0.865 0.06285 0.957 0.577 1.59 0.144 0.245 0.556 0.2549 1.16 0.714 1.87 PRS_PLINK_1.99526231496888e.06 370 Keratitis Both 190 2088 7 sense organs darkseagreen4 2088, 190 524, 45 525, 55 517, 47 522, 43 0.022 0.0748 0.768 0.1146 1.02 0.883 1.18 0.211 0.208 0.311 0.5075 1.24 0.821 1.86 0.0644 0.216 0.766 0.1158 1.07 0.698 1.63 -0.0453 0.22 0.837 0.07747 0.956 0.621 1.47 PRS_PLINK_1.99526231496888e.06 370.1 Corneal ulcer Both 97 1021 7 sense organs darkseagreen4 1021, 97 257, 25 256, 30 256, 21 252, 21 -0.0779 0.106 0.464 0.3332 0.925 0.751 1.14 0.243 0.286 0.394 0.4043 1.28 0.729 2.23 -0.195 0.302 0.518 0.2854 0.823 0.455 1.49 -0.148 0.303 0.625 0.204 0.862 0.476 1.56 PRS_PLINK_1.99526231496888e.06 371 Inflammation of the eye Both 2192 22200 7 sense organs darkseagreen4 22200, 2192 5586, 530 5536, 550 5525, 529 5545, 582 0.0313 0.0222 0.159 0.799 1.03 0.988 1.08 0.0462 0.0637 0.468 0.3293 1.05 0.924 1.19 0.0104 0.0642 0.872 0.05955 1.01 0.891 1.15 0.105 0.063 0.0966 1.015 1.11 0.981 1.26 PRS_PLINK_1.99526231496888e.06 371.1 Uveitis, noninfectious or NOS Both 307 3471 7 sense organs darkseagreen4 3471, 307 874, 66 865, 77 864, 81 868, 83 0.0997 0.0567 0.0789 1.103 1.1 0.989 1.23 0.146 0.173 0.4 0.3985 1.16 0.824 1.62 0.194 0.171 0.258 0.5884 1.21 0.868 1.7 0.235 0.17 0.167 0.7766 1.27 0.906 1.77 PRS_PLINK_1.99526231496888e.06 371.3 Inflammation of eyelids Both 1752 17237 7 sense organs darkseagreen4 17237, 1752 4371, 443 4258, 425 4295, 419 4307, 464 0.00939 0.0251 0.708 0.1498 1.01 0.961 1.06 -0.0151 0.0711 0.832 0.07988 0.985 0.857 1.13 -0.0361 0.0714 0.613 0.2128 0.965 0.839 1.11 0.062 0.0698 0.375 0.426 1.06 0.928 1.22 PRS_PLINK_1.99526231496888e.06 372 Disorders of conjunctiva Both 529 5408 7 sense organs darkseagreen4 5408, 529 1365, 126 1348, 128 1353, 136 1341, 139 0.0469 0.0443 0.29 0.5377 1.05 0.961 1.14 0.0253 0.131 0.847 0.07232 1.03 0.794 1.32 0.0919 0.129 0.476 0.3226 1.1 0.852 1.41 0.112 0.128 0.383 0.4167 1.12 0.87 1.44 PRS_PLINK_1.99526231496888e.06 374 Other disorders of eyelids Both 3803 40161 7 sense organs darkseagreen4 40161, 3803 10055, 890 10016, 1011 10109, 949 9969, 952 0.00951 0.0168 0.572 0.2428 1.01 0.977 1.04 0.132 0.0481 0.00613 2.213 1.14 1.04 1.25 0.0595 0.0487 0.222 0.6539 1.06 0.965 1.17 0.0782 0.0488 0.109 0.9641 1.08 0.983 1.19 PRS_PLINK_1.99526231496888e.06 374.1 Ectropion or entropion Both 641 6965 7 sense organs darkseagreen4 6965, 641 1741, 145 1750, 194 1734, 151 1739, 151 -0.0136 0.0409 0.74 0.1308 0.987 0.911 1.07 0.287 0.114 0.0122 1.913 1.33 1.06 1.67 0.0402 0.121 0.739 0.1314 1.04 0.822 1.32 0.0269 0.121 0.824 0.08407 1.03 0.811 1.3 PRS_PLINK_1.99526231496888e.06 374.3 Ptosis of eyelid Both 1222 12800 7 sense organs darkseagreen4 12800, 1222 3196, 282 3206, 320 3228, 337 3164, 283 -0.016 0.0299 0.592 0.228 0.984 0.928 1.04 0.124 0.0853 0.145 0.8391 1.13 0.958 1.34 0.168 0.0843 0.0467 1.33 1.18 1 1.4 0.0176 0.0877 0.841 0.07524 1.02 0.857 1.21 PRS_PLINK_1.99526231496888e.06 375 Disorders of lacrimal system Both 1523 15626 7 sense organs darkseagreen4 15626, 1523 3912, 371 3920, 385 3886, 379 3903, 388 0.0139 0.0266 0.601 0.2208 1.01 0.962 1.07 0.0358 0.0761 0.638 0.1953 1.04 0.893 1.2 0.027 0.0764 0.723 0.1406 1.03 0.885 1.19 0.0499 0.076 0.511 0.2912 1.05 0.906 1.22 PRS_PLINK_1.99526231496888e.06 375.2 Epiphora Both 636 6274 7 sense organs darkseagreen4 6274, 636 1572, 154 1568, 164 1568, 150 1564, 168 0.032 0.041 0.435 0.3614 1.03 0.953 1.12 0.0668 0.117 0.569 0.2447 1.07 0.849 1.35 -0.0227 0.12 0.849 0.07093 0.978 0.773 1.24 0.105 0.117 0.369 0.4333 1.11 0.883 1.4 PRS_PLINK_1.99526231496888e.06 376 Disorders of the orbit Both 52 610 7 sense organs darkseagreen4 610, 52 157, 12 148, 16 152, 14 153, 10 -0.108 0.144 0.452 0.3452 0.898 0.677 1.19 0.344 0.385 0.371 0.4303 1.41 0.663 3 0.164 0.396 0.68 0.1677 1.18 0.542 2.56 -0.111 0.418 0.79 0.1023 0.895 0.394 2.03 PRS_PLINK_1.99526231496888e.06 377 Disorders of optic nerve and visual pathways Both 228 2651 7 sense organs darkseagreen4 2651, 228 674, 64 651, 64 663, 45 662, 55 -0.0718 0.0706 0.309 0.5095 0.931 0.81 1.07 0.0234 0.184 0.898 0.04648 1.02 0.714 1.47 -0.354 0.2 0.0773 1.112 0.702 0.474 1.04 -0.131 0.19 0.49 0.3097 0.877 0.605 1.27 PRS_PLINK_1.99526231496888e.06 377.1 Optic atrophy Both 34 417 7 sense organs darkseagreen4 417, 34 107, 9 102, 7 104, 9 104, 9 -0.0181 0.167 0.914 0.03911 0.982 0.708 1.36 -0.163 0.482 0.736 0.1332 0.85 0.33 2.19 0.13 0.471 0.782 0.1068 1.14 0.453 2.87 0.132 0.465 0.776 0.1101 1.14 0.459 2.84 PRS_PLINK_1.99526231496888e.06 377.3 Optic neuritis/neuropathy Both 87 959 7 sense organs darkseagreen4 959, 87 240, 18 240, 27 238, 20 240, 22 0.0347 0.111 0.754 0.1226 1.04 0.833 1.29 0.386 0.31 0.214 0.6693 1.47 0.8 2.7 0.0815 0.327 0.803 0.09507 1.08 0.571 2.06 0.152 0.321 0.636 0.1963 1.16 0.62 2.19 PRS_PLINK_1.99526231496888e.06 378 Strabismus and other disorders of binocular eye movements Both 958 10370 7 sense organs darkseagreen4 10370, 958 2594, 243 2589, 259 2594, 226 2591, 228 -0.0423 0.0343 0.218 0.6618 0.959 0.896 1.03 0.0667 0.0934 0.475 0.3231 1.07 0.89 1.28 -0.0716 0.0964 0.458 0.3393 0.931 0.771 1.12 -0.0555 0.0962 0.564 0.2489 0.946 0.783 1.14 PRS_PLINK_1.99526231496888e.06 378.1 Strabismus (not specified as paralytic) Both 651 6823 7 sense organs darkseagreen4 6823, 651 1717, 167 1709, 182 1689, 154 1705, 146 -0.0658 0.0417 0.115 0.9393 0.936 0.863 1.02 0.089 0.112 0.428 0.369 1.09 0.877 1.36 -0.0688 0.117 0.555 0.256 0.933 0.743 1.17 -0.122 0.118 0.3 0.5225 0.885 0.702 1.12 PRS_PLINK_1.99526231496888e.06 378.2 Nystagmus and other irregular eye movements Both 125 1501 7 sense organs darkseagreen4 1501, 125 386, 36 364, 27 377, 27 373, 35 0.0205 0.0916 0.823 0.08476 1.02 0.853 1.22 -0.226 0.258 0.382 0.418 0.798 0.481 1.32 -0.248 0.259 0.339 0.4703 0.78 0.469 1.3 0.0129 0.244 0.958 0.01872 1.01 0.628 1.63 PRS_PLINK_1.99526231496888e.06 378.5 Paralytic strabismus Both 171 1962 7 sense organs darkseagreen4 1962, 171 495, 46 490, 36 489, 41 488, 48 0.0455 0.0804 0.572 0.2426 1.05 0.894 1.23 -0.216 0.228 0.344 0.4638 0.806 0.515 1.26 -0.0742 0.222 0.738 0.1319 0.928 0.601 1.43 0.0543 0.216 0.801 0.09621 1.06 0.692 1.61 PRS_PLINK_1.99526231496888e.06 379 Other disorders of eye Both 2311 25287 7 sense organs darkseagreen4 25287, 2311 6392, 594 6267, 566 6301, 583 6314, 566 -0.00345 0.0214 0.872 0.05946 0.997 0.956 1.04 -0.029 0.0613 0.637 0.1961 0.971 0.861 1.1 -0.00489 0.0609 0.936 0.02869 0.995 0.883 1.12 -0.0361 0.0614 0.557 0.2543 0.965 0.855 1.09 PRS_PLINK_1.99526231496888e.06 379.2 Disorders of vitreous body Both 875 9435 7 sense organs darkseagreen4 9435, 875 2372, 229 2353, 193 2349, 229 2357, 223 0.0109 0.035 0.754 0.1224 1.01 0.944 1.08 -0.166 0.102 0.102 0.9922 0.847 0.694 1.03 0.0128 0.0977 0.896 0.04768 1.01 0.836 1.23 -0.0154 0.0982 0.875 0.05791 0.985 0.812 1.19 PRS_PLINK_1.99526231496888e.06 379.3 Aphakia and other disorders of lens Both 1086 12029 7 sense organs darkseagreen4 12029, 1086 3041, 268 2981, 279 3017, 291 2984, 247 -0.0109 0.0312 0.727 0.1382 0.989 0.93 1.05 0.0578 0.0891 0.517 0.2866 1.06 0.89 1.26 0.0874 0.0883 0.322 0.492 1.09 0.918 1.3 -0.0642 0.0917 0.484 0.3151 0.938 0.784 1.12 PRS_PLINK_1.99526231496888e.06 379.4 Anomalies of pupillary function Both 49 522 7 sense organs darkseagreen4 522, 49 132, 18 129, 8 133, 7 128, 16 0.00383 0.145 0.979 0.009215 1 0.755 1.33 -0.786 0.423 0.0634 1.198 0.456 0.199 1.04 -0.917 0.435 0.0348 1.459 0.4 0.17 0.936 -0.0366 0.357 0.918 0.03705 0.964 0.479 1.94 PRS_PLINK_1.99526231496888e.06 379.5 Disorders of iris and ciliary body Both 262 2833 7 sense organs darkseagreen4 2833, 262 712, 61 705, 66 708, 64 707, 71 0.0641 0.0617 0.299 0.5242 1.07 0.945 1.2 0.0904 0.183 0.622 0.2064 1.09 0.764 1.57 0.0453 0.185 0.806 0.09355 1.05 0.728 1.5 0.172 0.181 0.343 0.4652 1.19 0.833 1.69 PRS_PLINK_1.99526231496888e.06 379.9 Pain, swelling or discharge of eye Both 102 1236 7 sense organs darkseagreen4 1236, 102 313, 27 309, 33 306, 18 308, 24 -0.0183 0.101 0.857 0.06708 0.982 0.805 1.2 0.19 0.267 0.478 0.3205 1.21 0.716 2.04 -0.369 0.305 0.227 0.6436 0.691 0.38 1.26 -0.0919 0.286 0.748 0.1259 0.912 0.52 1.6 PRS_PLINK_1.99526231496888e.06 380 Disorders of external ear Both 448 4445 7 sense organs darkseagreen4 4445, 448 1122, 102 1102, 115 1122, 125 1099, 106 0.00914 0.0488 0.852 0.0698 1.01 0.917 1.11 0.137 0.142 0.333 0.4774 1.15 0.869 1.51 0.191 0.139 0.17 0.7695 1.21 0.921 1.59 0.0723 0.145 0.618 0.2093 1.08 0.809 1.43 PRS_PLINK_1.99526231496888e.06 380.1 Otitis externa Both 342 3761 7 sense organs darkseagreen4 3761, 342 943, 71 940, 93 949, 95 928, 83 0.0505 0.0572 0.377 0.4237 1.05 0.94 1.18 0.276 0.163 0.0906 1.043 1.32 0.957 1.81 0.289 0.163 0.0752 1.124 1.34 0.971 1.84 0.173 0.167 0.299 0.5245 1.19 0.857 1.65 PRS_PLINK_1.99526231496888e.06 380.4 Impacted cerumen Both 250 2575 7 sense organs darkseagreen4 2575, 250 645, 59 642, 65 643, 63 644, 63 0.02 0.0643 0.756 0.1217 1.02 0.899 1.16 0.101 0.187 0.59 0.2293 1.11 0.767 1.59 0.077 0.188 0.681 0.1666 1.08 0.748 1.56 0.0815 0.189 0.667 0.1761 1.08 0.749 1.57 PRS_PLINK_1.99526231496888e.06 381 Otitis media and Eustachian tube disorders Both 1414 15684 7 sense organs darkseagreen4 15684, 1414 3923, 354 3936, 358 3911, 366 3910, 334 -0.0283 0.028 0.312 0.506 0.972 0.92 1.03 0.00895 0.0782 0.909 0.04153 1.01 0.866 1.18 0.0392 0.0778 0.615 0.2114 1.04 0.893 1.21 -0.0477 0.0796 0.549 0.2604 0.953 0.816 1.11 PRS_PLINK_1.99526231496888e.06 381.1 Otitis media Both 1156 12856 7 sense organs darkseagreen4 12856, 1156 3212, 291 3228, 293 3202, 292 3210, 279 -0.0321 0.0309 0.3 0.5231 0.968 0.911 1.03 0.00178 0.0863 0.984 0.007222 1 0.846 1.19 0.0114 0.0864 0.895 0.0483 1.01 0.854 1.2 -0.034 0.0874 0.697 0.1566 0.967 0.814 1.15 PRS_PLINK_1.99526231496888e.06 381.11 Suppurative and unspecified otitis media Both 553 6278 7 sense organs darkseagreen4 6278, 553 1603, 134 1535, 140 1569, 144 1570, 135 -0.00869 0.0443 0.844 0.07345 0.991 0.909 1.08 0.0855 0.125 0.495 0.305 1.09 0.852 1.39 0.0933 0.125 0.455 0.3423 1.1 0.86 1.4 0.036 0.127 0.777 0.1098 1.04 0.808 1.33 PRS_PLINK_1.99526231496888e.06 381.2 Eustachian tube disorders Both 135 1457 7 sense organs darkseagreen4 1457, 135 369, 36 361, 32 370, 36 357, 30 -0.0734 0.0905 0.417 0.3795 0.929 0.778 1.11 -0.0994 0.25 0.691 0.1602 0.905 0.554 1.48 0.0112 0.243 0.963 0.01625 1.01 0.628 1.63 -0.197 0.255 0.439 0.3574 0.821 0.498 1.35 PRS_PLINK_1.99526231496888e.06 381.3 Mastoiditis & related conditions Both 113 1243 7 sense organs darkseagreen4 1243, 113 312, 25 311, 28 310, 25 310, 35 0.132 0.0959 0.17 0.7704 1.14 0.945 1.38 0.168 0.282 0.55 0.2594 1.18 0.681 2.06 -0.0134 0.285 0.962 0.0166 0.987 0.564 1.73 0.318 0.269 0.238 0.6225 1.37 0.81 2.33 PRS_PLINK_1.99526231496888e.06 381.9 Otorrhea Both 185 2030 7 sense organs darkseagreen4 2030, 185 508, 51 508, 45 518, 60 496, 29 -0.114 0.0791 0.151 0.8202 0.893 0.764 1.04 -0.114 0.211 0.59 0.2295 0.892 0.59 1.35 0.144 0.198 0.467 0.3305 1.16 0.783 1.7 -0.524 0.238 0.0274 1.562 0.592 0.371 0.943 PRS_PLINK_1.99526231496888e.06 382 Otalgia Both 219 2306 7 sense organs darkseagreen4 2306, 219 577, 50 579, 55 572, 56 577, 58 0.0443 0.07 0.527 0.2783 1.05 0.911 1.2 0.0826 0.202 0.682 0.1661 1.09 0.732 1.61 0.138 0.202 0.494 0.306 1.15 0.773 1.71 0.183 0.201 0.362 0.4414 1.2 0.81 1.78 PRS_PLINK_1.99526231496888e.06 383 Otosclerosis Both 232 2353 7 sense organs darkseagreen4 2353, 232 588, 59 592, 63 587, 48 585, 62 0.0055 0.0682 0.936 0.02885 1.01 0.88 1.15 0.0574 0.188 0.76 0.1189 1.06 0.732 1.53 -0.21 0.2 0.294 0.5321 0.81 0.547 1.2 0.0559 0.189 0.768 0.1148 1.06 0.73 1.53 PRS_PLINK_1.99526231496888e.06 384 Other disorders of tympanic membrane Both 919 9595 7 sense organs darkseagreen4 9595, 919 2432, 235 2376, 240 2394, 219 2390, 225 -0.018 0.0347 0.605 0.2183 0.982 0.918 1.05 0.0486 0.0961 0.613 0.2129 1.05 0.87 1.27 -0.0461 0.0981 0.638 0.1949 0.955 0.788 1.16 -0.0205 0.0975 0.834 0.07894 0.98 0.809 1.19 PRS_PLINK_1.99526231496888e.06 384.4 Perforation of tympanic membrane Both 732 7653 7 sense organs darkseagreen4 7653, 732 1922, 187 1903, 187 1915, 177 1911, 181 -0.0158 0.039 0.685 0.1645 0.984 0.912 1.06 0.0194 0.108 0.857 0.06684 1.02 0.825 1.26 -0.0502 0.109 0.646 0.1896 0.951 0.767 1.18 -0.0247 0.109 0.821 0.08572 0.976 0.788 1.21 PRS_PLINK_1.99526231496888e.06 385 Other disorders of middle ear and mastoid Both 527 5736 7 sense organs darkseagreen4 5736, 527 1463, 126 1408, 127 1431, 130 1432, 144 0.0273 0.0449 0.543 0.2649 1.03 0.941 1.12 0.0297 0.131 0.821 0.0859 1.03 0.797 1.33 0.0671 0.13 0.606 0.2178 1.07 0.829 1.38 0.158 0.127 0.213 0.6721 1.17 0.913 1.5 PRS_PLINK_1.99526231496888e.06 385.3 Cholesteatoma Both 400 4423 7 sense organs darkseagreen4 4423, 400 1122, 97 1090, 99 1117, 97 1092, 107 0.00871 0.0522 0.867 0.06175 1.01 0.911 1.12 0.037 0.148 0.803 0.09534 1.04 0.776 1.39 0.0072 0.149 0.961 0.01709 1.01 0.753 1.35 0.132 0.146 0.365 0.4379 1.14 0.857 1.52 PRS_PLINK_1.99526231496888e.06 385.5 Tympanosclerosis and middle ear disease related to otitis media Both 170 1806 7 sense organs darkseagreen4 1806, 170 458, 49 445, 36 452, 36 451, 49 0.0386 0.0783 0.622 0.2065 1.04 0.892 1.21 -0.278 0.226 0.218 0.6617 0.757 0.486 1.18 -0.298 0.226 0.188 0.7265 0.742 0.477 1.16 0.0201 0.211 0.924 0.03425 1.02 0.675 1.54 PRS_PLINK_1.99526231496888e.06 386 Vertiginous syndromes and other disorders of vestibular system Both 1156 12518 7 sense organs darkseagreen4 12518, 1156 3134, 285 3127, 278 3139, 273 3116, 320 0.0692 0.0301 0.0214 1.67 1.07 1.01 1.14 -0.0231 0.0878 0.792 0.1011 0.977 0.823 1.16 -0.0446 0.0882 0.613 0.2126 0.956 0.805 1.14 0.125 0.0853 0.143 0.8452 1.13 0.959 1.34 PRS_PLINK_1.99526231496888e.06 386.1 Meniere's disease Both 369 4126 7 sense organs darkseagreen4 4126, 369 1042, 84 1021, 92 1050, 82 1011, 111 0.148 0.0522 0.00458 2.339 1.16 1.05 1.28 0.113 0.156 0.468 0.3294 1.12 0.825 1.52 -0.0268 0.16 0.867 0.06207 0.974 0.711 1.33 0.305 0.151 0.0428 1.368 1.36 1.01 1.82 PRS_PLINK_1.99526231496888e.06 386.2 Peripheral or central vertigo Both 250 2655 7 sense organs darkseagreen4 2655, 250 667, 68 665, 53 661, 62 662, 67 0.0424 0.0653 0.516 0.287 1.04 0.918 1.19 -0.232 0.19 0.221 0.6553 0.793 0.547 1.15 -0.0737 0.182 0.686 0.1636 0.929 0.65 1.33 0.00719 0.18 0.968 0.01402 1.01 0.707 1.43 PRS_PLINK_1.99526231496888e.06 386.3 Labyrinthitis Both 515 5560 7 sense organs darkseagreen4 5560, 515 1399, 123 1396, 128 1374, 126 1390, 138 0.0446 0.0449 0.321 0.4939 1.05 0.958 1.14 0.0448 0.131 0.733 0.135 1.05 0.809 1.35 0.0376 0.132 0.775 0.1105 1.04 0.802 1.34 0.126 0.129 0.331 0.48 1.13 0.88 1.46 PRS_PLINK_1.99526231496888e.06 386.9 Dizziness and giddiness (Light-headedness and vertigo) Both 2850 32587 7 sense organs darkseagreen4 32587, 2850 8140, 707 8185, 689 8117, 749 8136, 705 0.0299 0.0193 0.122 0.9148 1.03 0.992 1.07 -0.0313 0.0557 0.575 0.2404 0.969 0.869 1.08 0.0623 0.0547 0.255 0.5934 1.06 0.956 1.18 0.00236 0.0555 0.966 0.01497 1 0.899 1.12 PRS_PLINK_1.99526231496888e.06 388 Other disorders of ear Both 141 1463 7 sense organs darkseagreen4 1463, 141 371, 32 362, 34 364, 32 366, 43 0.124 0.0853 0.145 0.8399 1.13 0.958 1.34 0.0805 0.253 0.751 0.1244 1.08 0.659 1.78 0.0181 0.255 0.943 0.02528 1.02 0.618 1.68 0.309 0.243 0.203 0.6917 1.36 0.846 2.19 PRS_PLINK_1.99526231496888e.06 389 Hearing loss Both 2628 29264 7 sense organs darkseagreen4 29264, 2628 7309, 644 7353, 639 7299, 703 7296, 642 0.0112 0.0202 0.58 0.2364 1.01 0.972 1.05 -0.0129 0.0582 0.825 0.08358 0.987 0.881 1.11 0.0885 0.057 0.12 0.9192 1.09 0.977 1.22 0.00299 0.0583 0.959 0.01815 1 0.895 1.12 PRS_PLINK_1.99526231496888e.06 389.1 Sensorineural hearing loss Both 296 3179 7 sense organs darkseagreen4 3179, 296 800, 84 792, 68 792, 69 795, 75 -0.0136 0.0613 0.824 0.08395 0.986 0.875 1.11 -0.185 0.169 0.274 0.5619 0.831 0.596 1.16 -0.191 0.169 0.256 0.5915 0.826 0.593 1.15 -0.107 0.166 0.519 0.2852 0.898 0.649 1.24 PRS_PLINK_1.99526231496888e.06 389.2 Conductive hearing loss Both 296 3354 7 sense organs darkseagreen4 3354, 296 838, 75 843, 80 848, 72 824, 69 -0.0439 0.0614 0.475 0.3236 0.957 0.849 1.08 0.0648 0.167 0.698 0.1564 1.07 0.769 1.48 -0.0446 0.171 0.794 0.1003 0.956 0.685 1.34 -0.0478 0.173 0.782 0.1069 0.953 0.68 1.34 PRS_PLINK_1.99526231496888e.06 389.4 Tinnitus Both 336 3644 7 sense organs darkseagreen4 3644, 336 914, 86 913, 80 907, 103 909, 67 -0.0414 0.0573 0.471 0.3274 0.959 0.857 1.07 -0.0792 0.161 0.623 0.2054 0.924 0.674 1.27 0.186 0.153 0.222 0.6543 1.2 0.894 1.62 -0.242 0.168 0.15 0.8229 0.785 0.564 1.09 PRS_PLINK_1.99526231496888e.06 394 Rheumatic disease of the heart valves Both 2638 32790 8 circulatory system red 32790, 2638 8267, 627 8126, 616 8234, 699 8153, 696 0.0527 0.0198 0.00789 2.103 1.05 1.01 1.1 -0.000981 0.0588 0.987 0.005821 0.999 0.89 1.12 0.114 0.0571 0.0465 1.332 1.12 1 1.25 0.12 0.0572 0.0355 1.45 1.13 1.01 1.26 PRS_PLINK_1.99526231496888e.06 394.2 Mitral valve disease Both 1639 20116 8 circulatory system red 20116, 1639 5104, 376 4963, 385 5021, 424 5019, 454 0.0823 0.025 0.000995 3.002 1.09 1.03 1.14 0.0498 0.0751 0.507 0.295 1.05 0.907 1.22 0.138 0.0735 0.0605 1.218 1.15 0.994 1.33 0.204 0.0724 0.00477 2.321 1.23 1.06 1.41 PRS_PLINK_1.99526231496888e.06 394.3 Aortic valve disease Both 661 8535 8 circulatory system red 8535, 661 2153, 163 2122, 142 2127, 190 2132, 166 0.0284 0.04 0.479 0.3198 1.03 0.951 1.11 -0.126 0.118 0.286 0.5439 0.881 0.699 1.11 0.169 0.111 0.128 0.8933 1.18 0.953 1.47 0.0371 0.114 0.745 0.1278 1.04 0.83 1.3 PRS_PLINK_1.99526231496888e.06 394.7 Disease of tricuspid valve Both 555 7030 8 circulatory system red 7030, 555 1758, 132 1764, 129 1764, 152 1743, 142 0.0661 0.0434 0.128 0.8921 1.07 0.981 1.16 -0.0271 0.128 0.832 0.07977 0.973 0.758 1.25 0.141 0.123 0.254 0.5955 1.15 0.904 1.47 0.08 0.125 0.523 0.2816 1.08 0.848 1.38 PRS_PLINK_1.99526231496888e.06 395 Heart valve disorders Both 2254 28234 8 circulatory system red 28234, 2254 7138, 540 6971, 514 7066, 586 7050, 614 0.0687 0.0213 0.00128 2.893 1.07 1.03 1.12 -0.0275 0.0638 0.666 0.1765 0.973 0.858 1.1 0.0933 0.0619 0.132 0.8795 1.1 0.972 1.24 0.143 0.0613 0.0199 1.7 1.15 1.02 1.3 PRS_PLINK_1.99526231496888e.06 395.1 Nonrheumatic mitral valve disorders Both 1586 19409 8 circulatory system red 19409, 1586 4928, 366 4769, 364 4851, 415 4852, 441 0.0853 0.0253 0.00076 3.119 1.09 1.04 1.14 0.0249 0.0766 0.745 0.1279 1.03 0.882 1.19 0.144 0.0744 0.0531 1.275 1.15 0.998 1.34 0.202 0.0735 0.00602 2.22 1.22 1.06 1.41 PRS_PLINK_1.99526231496888e.06 395.2 Nonrheumatic aortic valve disorders Both 132 1822 8 circulatory system red 1822, 132 456, 29 461, 35 449, 34 456, 34 0.0917 0.0916 0.317 0.4989 1.1 0.916 1.31 0.164 0.256 0.523 0.2817 1.18 0.713 1.94 0.165 0.256 0.521 0.2834 1.18 0.714 1.95 0.169 0.256 0.508 0.2941 1.18 0.717 1.96 PRS_PLINK_1.99526231496888e.06 395.3 Nonrheumatic tricuspid valve disorders Both 57 709 8 circulatory system red 709, 57 182, 14 174, 12 177, 18 176, 13 -0.0137 0.135 0.919 0.03669 0.986 0.757 1.28 -0.149 0.395 0.706 0.1509 0.862 0.398 1.87 0.245 0.363 0.499 0.3022 1.28 0.628 2.6 -0.0673 0.393 0.864 0.06343 0.935 0.432 2.02 PRS_PLINK_1.99526231496888e.06 395.4 Nonrheumatic pulmonary valve disorders Both 51 657 8 circulatory system red 657, 51 168, 12 161, 12 164, 16 164, 11 -0.011 0.136 0.936 0.02883 0.989 0.758 1.29 0.248 0.412 0.547 0.2619 1.28 0.572 2.87 0.425 0.387 0.272 0.5655 1.53 0.716 3.27 -0.128 0.411 0.756 0.1214 0.88 0.393 1.97 PRS_PLINK_1.99526231496888e.06 395.6 Heart valve replaced Both 743 9813 8 circulatory system red 9813, 743 2457, 187 2462, 179 2439, 179 2453, 198 0.0453 0.0374 0.225 0.6472 1.05 0.972 1.13 -0.0427 0.108 0.693 0.1595 0.958 0.775 1.18 -0.0379 0.108 0.726 0.1391 0.963 0.779 1.19 0.0631 0.106 0.55 0.2593 1.07 0.866 1.31 PRS_PLINK_1.99526231496888e.06 396 Abnormal heart sounds Both 700 7655 8 circulatory system red 7655, 700 1924, 169 1904, 161 1923, 182 1900, 188 0.0454 0.0395 0.25 0.6013 1.05 0.968 1.13 -0.042 0.114 0.714 0.1465 0.959 0.766 1.2 0.0746 0.111 0.502 0.2991 1.08 0.866 1.34 0.12 0.111 0.28 0.5534 1.13 0.907 1.4 PRS_PLINK_1.99526231496888e.06 401 Hypertension Both 43185 207901 8 circulatory system red 207901, 43185 51949, 10646 51983, 10042 52229, 11010 51682, 11468 0.0192 0.00539 0.000367 3.436 1.02 1.01 1.03 -0.0763 0.0156 1.07e-06 5.969 0.927 0.899 0.955 -0.00543 0.0154 0.724 0.1403 0.995 0.965 1.03 0.0177 0.0153 0.247 0.6071 1.02 0.988 1.05 PRS_PLINK_1.99526231496888e.06 401.1 Essential hypertension Both 43131 207712 8 circulatory system red 207712, 43131 51907, 10631 51940, 10028 52171, 11002 51637, 11451 0.0193 0.00539 0.00034 3.468 1.02 1.01 1.03 -0.0762 0.0157 1.12e-06 5.95 0.927 0.899 0.955 -0.00487 0.0154 0.751 0.1242 0.995 0.966 1.03 0.0176 0.0153 0.249 0.6037 1.02 0.988 1.05 PRS_PLINK_1.99526231496888e.06 401.2 Hypertensive heart and/or renal disease Both 349 13252 8 circulatory system red 13252, 349 3328, 81 3308, 77 3307, 92 3306, 99 0.0746 0.0522 0.153 0.8148 1.08 0.973 1.19 -0.0378 0.159 0.812 0.09025 0.963 0.705 1.32 0.136 0.153 0.372 0.4296 1.15 0.85 1.55 0.212 0.151 0.159 0.7975 1.24 0.92 1.66 PRS_PLINK_1.99526231496888e.06 401.21 Hypertensive heart disease Both 157 2564 8 circulatory system red 2564, 157 644, 36 640, 37 638, 30 641, 54 0.0953 0.0776 0.219 0.6591 1.1 0.945 1.28 0.00295 0.236 0.99 0.004356 1 0.632 1.59 -0.197 0.248 0.427 0.37 0.821 0.505 1.33 0.418 0.219 0.0562 1.25 1.52 0.989 2.33 PRS_PLINK_1.99526231496888e.06 401.22 Hypertensive chronic kidney disease Both 192 10832 8 circulatory system red 10832, 192 2716, 42 2712, 38 2708, 66 2695, 46 0.0867 0.07 0.216 0.6664 1.09 0.951 1.25 -0.0917 0.22 0.677 0.1693 0.912 0.593 1.4 0.472 0.196 0.016 1.796 1.6 1.09 2.35 0.119 0.211 0.572 0.2427 1.13 0.745 1.7 PRS_PLINK_1.99526231496888e.06 401.3 Other hypertensive complications Both 29 1048 8 circulatory system red 1048, 29 263, 5 261, 7 262, 7 262, 10 0.145 0.177 0.415 0.3823 1.16 0.816 1.64 0.277 0.52 0.594 0.2261 1.32 0.476 3.66 0.287 0.516 0.578 0.238 1.33 0.485 3.66 0.63 0.491 0.2 0.6993 1.88 0.717 4.91 PRS_PLINK_1.99526231496888e.06 402 Elevated blood pressure reading without diagnosis of hypertension Both 908 10889 8 circulatory system red 10889, 908 2723, 241 2724, 185 2754, 251 2685, 230 0.0274 0.0346 0.428 0.3683 1.03 0.96 1.1 -0.265 0.101 0.00884 2.054 0.767 0.629 0.936 0.0284 0.0939 0.763 0.1176 1.03 0.856 1.24 -0.0306 0.0959 0.749 0.1253 0.97 0.804 1.17 PRS_PLINK_1.99526231496888e.06 411 Ischemic Heart Disease Both 17437 150784 8 circulatory system red 150784, 17437 37758, 4292 37611, 4172 37672, 4449 37696, 4514 0.0128 0.00795 0.108 0.9668 1.01 0.997 1.03 -0.0273 0.0231 0.237 0.6249 0.973 0.93 1.02 0.0227 0.0228 0.32 0.4955 1.02 0.978 1.07 0.0195 0.0227 0.391 0.4083 1.02 0.975 1.07 PRS_PLINK_1.99526231496888e.06 411.1 Unstable angina (intermediate coronary syndrome) Both 2818 35061 8 circulatory system red 35061, 2818 8757, 676 8776, 704 8757, 717 8762, 721 0.0267 0.0193 0.166 0.7804 1.03 0.989 1.07 0.038 0.0559 0.497 0.3039 1.04 0.931 1.16 0.0612 0.0557 0.271 0.5666 1.06 0.953 1.19 0.0685 0.0556 0.218 0.6616 1.07 0.96 1.19 PRS_PLINK_1.99526231496888e.06 411.2 Myocardial infarction Both 6320 76419 8 circulatory system red 76419, 6320 19153, 1592 19098, 1514 19088, 1581 19053, 1630 0.0151 0.0129 0.242 0.6163 1.02 0.99 1.04 -0.0469 0.0373 0.209 0.6792 0.954 0.887 1.03 -0.0057 0.0369 0.877 0.05677 0.994 0.925 1.07 0.0273 0.0367 0.457 0.3398 1.03 0.956 1.1 PRS_PLINK_1.99526231496888e.06 411.3 Angina pectoris Both 8723 98965 8 circulatory system red 98965, 8723 25035, 2230 24426, 2105 24733, 2195 24741, 2190 -0.00125 0.0111 0.91 0.04094 0.999 0.977 1.02 -0.0333 0.0317 0.293 0.5332 0.967 0.909 1.03 -0.00854 0.0314 0.786 0.1048 0.991 0.932 1.05 -0.0148 0.0314 0.638 0.195 0.985 0.926 1.05 PRS_PLINK_1.99526231496888e.06 411.4 Coronary atherosclerosis Both 11218 107549 8 circulatory system red 107549, 11218 27261, 2850 26499, 2641 26954, 2823 26803, 2895 0.0101 0.00982 0.305 0.5154 1.01 0.991 1.03 -0.0496 0.0284 0.081 1.092 0.952 0.9 1.01 -0.00924 0.028 0.741 0.1299 0.991 0.938 1.05 0.00972 0.0279 0.727 0.1383 1.01 0.956 1.07 PRS_PLINK_1.99526231496888e.06 411.41 Aneurysm and dissection of heart Both 424 4851 8 circulatory system red 4851, 424 1217, 104 1217, 115 1209, 94 1207, 111 0.00224 0.0501 0.964 0.01579 1 0.909 1.11 0.0958 0.14 0.495 0.3053 1.1 0.836 1.45 -0.0931 0.147 0.527 0.2785 0.911 0.683 1.22 0.0796 0.142 0.574 0.2408 1.08 0.82 1.43 PRS_PLINK_1.99526231496888e.06 411.8 Other chronic ischemic heart disease, unspecified Both 7773 89870 8 circulatory system red 89870, 7773 22704, 1914 22276, 1921 22399, 1963 22460, 1971 0.0127 0.0117 0.275 0.5613 1.01 0.99 1.04 0.0223 0.0337 0.508 0.2945 1.02 0.957 1.09 0.0302 0.0335 0.368 0.4345 1.03 0.965 1.1 0.0284 0.0335 0.396 0.4027 1.03 0.963 1.1 PRS_PLINK_1.99526231496888e.06 411.9 Other acute and subacute forms of ischemic heart disease Both 695 8291 8 circulatory system red 8291, 695 2075, 168 2069, 189 2075, 165 2070, 173 -0.00451 0.0388 0.908 0.04214 0.996 0.923 1.07 0.123 0.11 0.266 0.5756 1.13 0.911 1.4 -0.0222 0.113 0.845 0.07313 0.978 0.783 1.22 0.0384 0.112 0.733 0.135 1.04 0.834 1.3 PRS_PLINK_1.99526231496888e.06 414 Other forms of chronic heart disease Both 879 12319 8 circulatory system red 12319, 879 3083, 233 3074, 207 3083, 227 3076, 211 -0.00455 0.0346 0.895 0.04811 0.995 0.93 1.07 -0.11 0.0986 0.265 0.5767 0.896 0.738 1.09 -0.02 0.0964 0.835 0.07814 0.98 0.811 1.18 -0.0918 0.0982 0.35 0.456 0.912 0.753 1.11 PRS_PLINK_1.99526231496888e.06 414.2 ASCVD Both 38 477 8 circulatory system red 477, 38 120, 9 119, 9 119, 14 119, 6 0.0475 0.16 0.767 0.1153 1.05 0.766 1.44 0.0356 0.455 0.938 0.028 1.04 0.425 2.53 0.391 0.422 0.353 0.4522 1.48 0.647 3.38 -0.36 0.497 0.469 0.3292 0.698 0.264 1.85 PRS_PLINK_1.99526231496888e.06 415 Pulmonary heart disease Both 2401 31183 8 circulatory system red 31183, 2401 7785, 578 7805, 587 7795, 606 7783, 630 0.0394 0.0208 0.0578 1.238 1.04 0.999 1.08 0.0154 0.0607 0.8 0.09677 1.02 0.902 1.14 0.0519 0.0603 0.39 0.4094 1.05 0.936 1.19 0.091 0.0598 0.128 0.8916 1.1 0.974 1.23 PRS_PLINK_1.99526231496888e.06 415.11 Pulmonary embolism and infarction, acute Both 44 513 8 circulatory system red 513, 44 132, 10 125, 14 133, 8 123, 12 -0.0447 0.151 0.767 0.1154 0.956 0.712 1.29 0.305 0.418 0.466 0.3319 1.36 0.598 3.07 -0.131 0.457 0.774 0.1113 0.877 0.358 2.15 0.189 0.427 0.658 0.1821 1.21 0.523 2.79 PRS_PLINK_1.99526231496888e.06 415.2 Chronic pulmonary heart disease Both 266 4029 8 circulatory system red 4029, 266 1005, 68 1015, 60 1001, 65 1005, 73 0.0922 0.0623 0.139 0.8566 1.1 0.97 1.24 -0.138 0.181 0.446 0.3503 0.871 0.611 1.24 -0.0371 0.177 0.834 0.07885 0.964 0.681 1.36 0.0565 0.173 0.744 0.1284 1.06 0.754 1.49 PRS_PLINK_1.99526231496888e.06 415.21 Primary pulmonary hypertension Both 197 3027 8 circulatory system red 3027, 197 757, 58 760, 43 756, 44 752, 52 0.0489 0.0728 0.502 0.2991 1.05 0.91 1.21 -0.306 0.205 0.136 0.8669 0.737 0.493 1.1 -0.273 0.203 0.179 0.7462 0.761 0.511 1.13 -0.102 0.196 0.6 0.2215 0.903 0.615 1.32 PRS_PLINK_1.99526231496888e.06 416 Cardiomegaly Both 1300 17990 8 circulatory system red 17990, 1300 4495, 332 4496, 309 4511, 331 4482, 328 0.0299 0.0281 0.288 0.541 1.03 0.975 1.09 -0.0693 0.0817 0.396 0.4023 0.933 0.795 1.09 -0.00453 0.0803 0.955 0.01997 0.995 0.85 1.17 -0.0041 0.0806 0.959 0.01797 0.996 0.85 1.17 PRS_PLINK_1.99526231496888e.06 418 Nonspecific chest pain Both 18523 198416 8 circulatory system red 198416, 18523 49625, 4482 49695, 4519 49776, 4834 49260, 4682 0.026 0.00763 0.000652 3.186 1.03 1.01 1.04 0.00608 0.022 0.782 0.1066 1.01 0.964 1.05 0.0698 0.0217 0.0013 2.885 1.07 1.03 1.12 0.0473 0.0219 0.0304 1.517 1.05 1 1.09 PRS_PLINK_1.99526231496888e.06 418.1 Precordial pain Both 2284 25880 8 circulatory system red 25880, 2284 6465, 525 6489, 616 6530, 548 6389, 593 0.0446 0.0216 0.0391 1.408 1.05 1 1.09 0.159 0.0619 0.0104 1.983 1.17 1.04 1.32 0.0382 0.0635 0.548 0.2616 1.04 0.917 1.18 0.139 0.0626 0.0263 1.58 1.15 1.02 1.3 PRS_PLINK_1.99526231496888e.06 420 Carditis Both 1212 14499 8 circulatory system red 14499, 1212 3633, 290 3616, 287 3627, 313 3619, 322 0.0662 0.0292 0.0235 1.629 1.07 1.01 1.13 -0.0123 0.0864 0.887 0.05202 0.988 0.834 1.17 0.0763 0.0847 0.367 0.4351 1.08 0.914 1.27 0.108 0.0842 0.2 0.6987 1.11 0.944 1.31 PRS_PLINK_1.99526231496888e.06 420.1 Myocarditis Both 74 906 8 circulatory system red 906, 74 227, 15 226, 16 226, 25 227, 18 0.0423 0.121 0.727 0.1384 1.04 0.822 1.32 0.104 0.358 0.771 0.113 1.11 0.55 2.24 0.461 0.331 0.164 0.786 1.59 0.829 3.03 0.19 0.352 0.59 0.2293 1.21 0.607 2.41 PRS_PLINK_1.99526231496888e.06 420.2 Pericarditis Both 783 9266 8 circulatory system red 9266, 783 2338, 186 2294, 177 2321, 199 2311, 221 0.107 0.036 0.00288 2.541 1.11 1.04 1.19 -0.0373 0.109 0.732 0.1358 0.963 0.779 1.19 0.0737 0.106 0.486 0.3133 1.08 0.875 1.32 0.184 0.103 0.0757 1.121 1.2 0.981 1.47 PRS_PLINK_1.99526231496888e.06 420.21 Acute pericarditis Both 152 1553 8 circulatory system red 1553, 152 391, 35 386, 43 395, 42 381, 32 -0.011 0.0829 0.894 0.04849 0.989 0.841 1.16 0.196 0.235 0.405 0.3931 1.22 0.767 1.93 0.182 0.236 0.441 0.3559 1.2 0.755 1.91 -0.0785 0.252 0.755 0.122 0.924 0.564 1.51 PRS_PLINK_1.99526231496888e.06 420.22 Chronic pericarditis Both 62 736 8 circulatory system red 736, 62 185, 16 183, 15 186, 14 182, 17 0.096 0.125 0.443 0.3536 1.1 0.861 1.41 -0.0279 0.366 0.939 0.02719 0.973 0.474 1.99 -0.162 0.369 0.66 0.1806 0.85 0.413 1.75 0.0583 0.351 0.868 0.06132 1.06 0.532 2.11 PRS_PLINK_1.99526231496888e.06 420.3 Endocarditis Both 400 4851 8 circulatory system red 4851, 400 1210, 98 1221, 107 1204, 98 1213, 97 -0.00628 0.0519 0.904 0.04398 0.994 0.898 1.1 0.0692 0.145 0.633 0.1988 1.07 0.807 1.42 -0.00238 0.148 0.987 0.005616 0.998 0.747 1.33 -0.0151 0.148 0.919 0.03686 0.985 0.737 1.32 PRS_PLINK_1.99526231496888e.06 425 Cardiomyopathy Both 608 8768 8 circulatory system red 8768, 608 2192, 143 2191, 146 2195, 162 2188, 157 0.0527 0.0411 0.199 0.7006 1.05 0.973 1.14 0.0282 0.121 0.815 0.0886 1.03 0.811 1.3 0.122 0.118 0.301 0.5221 1.13 0.897 1.42 0.106 0.119 0.372 0.429 1.11 0.88 1.4 PRS_PLINK_1.99526231496888e.06 425.1 Primary/intrinsic cardiomyopathies Both 596 8515 8 circulatory system red 8515, 596 2143, 143 2114, 145 2141, 156 2116, 152 0.0424 0.0416 0.308 0.5117 1.04 0.962 1.13 0.0344 0.121 0.777 0.1097 1.03 0.816 1.31 0.088 0.119 0.46 0.3369 1.09 0.864 1.38 0.0854 0.12 0.477 0.3212 1.09 0.861 1.38 PRS_PLINK_1.99526231496888e.06 425.11 Hypertrophic obstructive cardiomyopathy Both 68 931 8 circulatory system red 931, 68 233, 21 233, 16 235, 15 230, 16 -0.0277 0.124 0.823 0.08455 0.973 0.763 1.24 -0.212 0.335 0.526 0.2788 0.809 0.419 1.56 -0.329 0.337 0.329 0.4824 0.72 0.372 1.39 -0.228 0.337 0.497 0.3033 0.796 0.411 1.54 PRS_PLINK_1.99526231496888e.06 425.12 Other hypertrophic cardiomyopathy Both 89 1171 8 circulatory system red 1171, 89 294, 27 294, 16 290, 20 293, 26 0.00599 0.109 0.956 0.01941 1.01 0.812 1.25 -0.513 0.318 0.106 0.9739 0.599 0.321 1.12 -0.288 0.299 0.336 0.4741 0.75 0.418 1.35 -0.0488 0.282 0.863 0.06418 0.952 0.548 1.65 PRS_PLINK_1.99526231496888e.06 425.8 Other cardiomyopathy Both 28 403 8 circulatory system red 403, 28 101, 4 103, 3 98, 13 101, 8 0.346 0.173 0.0462 1.335 1.41 1.01 1.98 -0.207 0.705 0.769 0.1141 0.813 0.204 3.24 0.92 0.534 0.0852 1.069 2.51 0.88 7.15 0.442 0.564 0.433 0.3636 1.56 0.515 4.7 PRS_PLINK_1.99526231496888e.06 426 Cardiac conduction disorders Both 3814 46144 8 circulatory system red 46144, 3814 11599, 981 11529, 967 11476, 951 11521, 913 -0.0245 0.0167 0.144 0.8422 0.976 0.944 1.01 -0.00722 0.0472 0.878 0.05633 0.993 0.905 1.09 -0.0171 0.0474 0.719 0.1435 0.983 0.896 1.08 -0.058 0.0479 0.226 0.6455 0.944 0.859 1.04 PRS_PLINK_1.99526231496888e.06 426.2 Atrioventricular [AV] block Both 1125 13826 8 circulatory system red 13826, 1125 3463, 315 3454, 274 3447, 272 3457, 264 -0.0488 0.0311 0.117 0.9325 0.952 0.896 1.01 -0.137 0.0858 0.11 0.959 0.872 0.737 1.03 -0.139 0.086 0.106 0.9744 0.87 0.735 1.03 -0.163 0.0868 0.06 1.222 0.849 0.716 1.01 PRS_PLINK_1.99526231496888e.06 426.21 First degree AV block Both 527 6397 8 circulatory system red 6397, 527 1604, 145 1604, 130 1589, 125 1598, 127 -0.0379 0.0454 0.404 0.3931 0.963 0.881 1.05 -0.108 0.125 0.386 0.4132 0.897 0.702 1.15 -0.13 0.127 0.303 0.5187 0.878 0.685 1.12 -0.114 0.126 0.367 0.4356 0.892 0.697 1.14 PRS_PLINK_1.99526231496888e.06 426.23 Second degree AV block Both 268 2957 8 circulatory system red 2957, 268 739, 74 739, 59 748, 74 730, 61 -0.0161 0.064 0.802 0.09595 0.984 0.868 1.12 -0.228 0.181 0.207 0.6839 0.796 0.559 1.13 -0.0177 0.171 0.918 0.03727 0.982 0.702 1.37 -0.184 0.179 0.304 0.5169 0.832 0.585 1.18 PRS_PLINK_1.99526231496888e.06 426.24 Atrioventricular block, complete Both 289 3853 8 circulatory system red 3853, 289 966, 76 965, 74 963, 74 958, 65 -0.0684 0.0606 0.259 0.5867 0.934 0.829 1.05 -0.0307 0.168 0.855 0.06809 0.97 0.698 1.35 -0.0233 0.168 0.89 0.05066 0.977 0.703 1.36 -0.134 0.174 0.441 0.3558 0.875 0.622 1.23 PRS_PLINK_1.99526231496888e.06 426.25 Other heart block Both 75 868 8 circulatory system red 868, 75 219, 18 214, 19 217, 17 217, 21 0.106 0.118 0.367 0.435 1.11 0.883 1.4 0.0216 0.332 0.948 0.02311 1.02 0.533 1.96 -0.0531 0.339 0.875 0.05777 0.948 0.488 1.84 0.149 0.326 0.647 0.1888 1.16 0.613 2.2 PRS_PLINK_1.99526231496888e.06 426.3 Bundle branch block Both 1850 22379 8 circulatory system red 22379, 1850 5616, 451 5596, 450 5672, 498 5484, 450 0.00745 0.0237 0.754 0.1228 1.01 0.962 1.06 0.00266 0.0692 0.969 0.01352 1 0.876 1.15 0.0912 0.0676 0.178 0.7507 1.1 0.959 1.25 0.0281 0.0693 0.685 0.1642 1.03 0.898 1.18 PRS_PLINK_1.99526231496888e.06 426.31 Right bundle branch block Both 840 10047 8 circulatory system red 10047, 840 2532, 194 2489, 200 2565, 241 2455, 205 0.0256 0.0352 0.467 0.3306 1.03 0.958 1.1 0.0563 0.104 0.59 0.2294 1.06 0.862 1.3 0.206 0.1 0.0403 1.395 1.23 1.01 1.49 0.0993 0.104 0.34 0.4691 1.1 0.901 1.35 PRS_PLINK_1.99526231496888e.06 426.32 Left bundle branch block Both 947 11678 8 circulatory system red 11678, 947 2947, 241 2918, 236 2947, 249 2862, 220 -0.00859 0.0332 0.796 0.09909 0.991 0.929 1.06 -0.00886 0.095 0.926 0.03354 0.991 0.823 1.19 0.0363 0.0939 0.699 0.1554 1.04 0.863 1.25 -0.057 0.0968 0.556 0.2551 0.945 0.781 1.14 PRS_PLINK_1.99526231496888e.06 426.4 Anomalous atrioventricular excitation Both 163 1747 8 circulatory system red 1747, 163 438, 43 436, 43 438, 38 435, 39 -0.0752 0.082 0.359 0.4449 0.928 0.79 1.09 -0.00514 0.223 0.982 0.00807 0.995 0.643 1.54 -0.13 0.23 0.572 0.2425 0.878 0.56 1.38 -0.0648 0.229 0.778 0.1092 0.937 0.598 1.47 PRS_PLINK_1.99526231496888e.06 426.8 Other cardiac conduction disorders Both 38 404 8 circulatory system red 404, 38 104, 5 98, 6 101, 13 101, 14 0.34 0.167 0.0423 1.374 1.4 1.01 1.95 0.212 0.569 0.71 0.1489 1.24 0.405 3.77 0.87 0.497 0.08 1.097 2.39 0.901 6.32 1.01 0.501 0.0431 1.366 2.76 1.03 7.36 PRS_PLINK_1.99526231496888e.06 426.9 Cardiac pacemaker/device in situ Both 1258 16287 8 circulatory system red 16287, 1258 4087, 312 4052, 332 4074, 322 4068, 291 -0.0352 0.0292 0.228 0.6429 0.965 0.912 1.02 0.0695 0.0817 0.395 0.4034 1.07 0.913 1.26 0.0396 0.0823 0.63 0.2004 1.04 0.885 1.22 -0.0606 0.0844 0.473 0.3252 0.941 0.798 1.11 PRS_PLINK_1.99526231496888e.06 426.91 Cardiac pacemaker in situ Both 1155 14951 8 circulatory system red 14951, 1155 3736, 285 3745, 313 3730, 294 3734, 262 -0.0443 0.0305 0.146 0.8354 0.957 0.901 1.02 0.0907 0.0849 0.285 0.5446 1.09 0.927 1.29 0.0387 0.0861 0.653 0.1852 1.04 0.878 1.23 -0.0793 0.0886 0.371 0.4309 0.924 0.777 1.1 PRS_PLINK_1.99526231496888e.06 427 Cardiac dysrhythmias Both 14168 146668 8 circulatory system red 146668, 14168 36617, 3484 36823, 3553 36521, 3567 36657, 3559 0.00384 0.00875 0.66 0.1801 1 0.987 1.02 0.0127 0.025 0.61 0.2146 1.01 0.964 1.06 0.0201 0.025 0.421 0.3759 1.02 0.972 1.07 0.00546 0.025 0.827 0.08239 1.01 0.957 1.06 PRS_PLINK_1.99526231496888e.06 427.1 Paroxysmal tachycardia, unspecified Both 1998 22708 8 circulatory system red 22708, 1998 5678, 496 5669, 496 5692, 507 5661, 498 0.01 0.0232 0.665 0.177 1.01 0.965 1.06 0.00159 0.0661 0.981 0.008435 1 0.88 1.14 0.024 0.0659 0.716 0.1452 1.02 0.9 1.17 0.0132 0.0662 0.842 0.07485 1.01 0.89 1.15 PRS_PLINK_1.99526231496888e.06 427.11 Paroxysmal supraventricular tachycardia Both 1538 16947 8 circulatory system red 16947, 1538 4237, 380 4233, 391 4269, 389 4204, 377 0.00462 0.0266 0.862 0.06442 1 0.954 1.06 0.0278 0.0751 0.711 0.1482 1.03 0.887 1.19 0.02 0.0752 0.79 0.1022 1.02 0.88 1.18 0.0024 0.0759 0.975 0.01108 1 0.864 1.16 PRS_PLINK_1.99526231496888e.06 427.12 Paroxysmal ventricular tachycardia Both 501 6314 8 circulatory system red 6314, 501 1623, 130 1536, 118 1596, 128 1555, 124 -0.01 0.046 0.828 0.08212 0.99 0.905 1.08 -0.0213 0.132 0.872 0.0597 0.979 0.756 1.27 0.0133 0.129 0.918 0.03706 1.01 0.787 1.3 0.018 0.13 0.89 0.05065 1.02 0.789 1.31 PRS_PLINK_1.99526231496888e.06 427.2 Atrial fibrillation and flutter Both 7861 90141 8 circulatory system red 90141, 7861 22823, 1937 22408, 1990 22384, 1957 22493, 1974 0.00834 0.0116 0.472 0.326 1.01 0.986 1.03 0.0458 0.0333 0.168 0.7739 1.05 0.981 1.12 0.0259 0.0334 0.439 0.3576 1.03 0.961 1.1 0.0248 0.0334 0.458 0.3394 1.03 0.96 1.09 PRS_PLINK_1.99526231496888e.06 427.3 Other specified cardiac dysrhythmias Both 1921 22082 8 circulatory system red 22082, 1921 5553, 481 5494, 496 5515, 447 5511, 495 -0.00215 0.0237 0.928 0.0326 0.998 0.953 1.05 0.044 0.0667 0.509 0.2929 1.04 0.917 1.19 -0.063 0.0683 0.356 0.4482 0.939 0.821 1.07 0.0423 0.0668 0.527 0.278 1.04 0.915 1.19 PRS_PLINK_1.99526231496888e.06 427.4 Cardiac arrest and ventricular fibrillation Both 591 8043 8 circulatory system red 8043, 591 2020, 168 2000, 133 2011, 151 2009, 139 -0.0265 0.0421 0.528 0.2774 0.974 0.897 1.06 -0.234 0.12 0.0514 1.289 0.792 0.626 1 -0.101 0.116 0.385 0.415 0.904 0.72 1.13 -0.173 0.119 0.145 0.8376 0.841 0.667 1.06 PRS_PLINK_1.99526231496888e.06 427.41 Ventricular fibrillation and flutter Both 190 2342 8 circulatory system red 2342, 190 592, 56 583, 44 586, 49 581, 41 -0.0727 0.0754 0.335 0.4753 0.93 0.802 1.08 -0.179 0.208 0.391 0.4078 0.836 0.556 1.26 -0.121 0.202 0.548 0.2612 0.886 0.597 1.32 -0.257 0.212 0.225 0.6477 0.773 0.511 1.17 PRS_PLINK_1.99526231496888e.06 427.42 Cardiac arrest Both 476 6663 8 circulatory system red 6663, 476 1666, 131 1665, 109 1667, 119 1662, 117 -0.00407 0.0465 0.93 0.03136 0.996 0.909 1.09 -0.192 0.134 0.15 0.8246 0.825 0.635 1.07 -0.0837 0.131 0.522 0.2822 0.92 0.712 1.19 -0.0936 0.131 0.476 0.3221 0.911 0.704 1.18 PRS_PLINK_1.99526231496888e.06 427.5 Arrhythmia (cardiac) NOS Both 554 6551 8 circulatory system red 6551, 554 1641, 139 1635, 133 1638, 146 1637, 136 0.00974 0.0434 0.823 0.08478 1.01 0.927 1.1 -0.0439 0.126 0.727 0.1385 0.957 0.748 1.22 0.0556 0.123 0.651 0.1862 1.06 0.831 1.35 -0.00202 0.125 0.987 0.005617 0.998 0.781 1.28 PRS_PLINK_1.99526231496888e.06 427.6 Premature beats Both 333 3786 8 circulatory system red 3786, 333 948, 85 942, 71 952, 95 941, 82 0.05 0.0557 0.369 0.4333 1.05 0.943 1.17 -0.173 0.166 0.298 0.526 0.841 0.608 1.16 0.118 0.155 0.447 0.3499 1.13 0.83 1.53 -0.0309 0.161 0.847 0.07191 0.97 0.708 1.33 PRS_PLINK_1.99526231496888e.06 427.61 Supraventricular premature beats Both 73 831 8 circulatory system red 831, 73 209, 27 206, 18 208, 12 207, 16 -0.175 0.124 0.16 0.7966 0.84 0.658 1.07 -0.398 0.311 0.2 0.6994 0.671 0.365 1.23 -0.726 0.348 0.0368 1.434 0.484 0.245 0.957 -0.499 0.327 0.128 0.8944 0.607 0.32 1.15 PRS_PLINK_1.99526231496888e.06 427.7 Tachycardia NOS Both 1309 15806 8 circulatory system red 15806, 1309 3950, 312 3952, 319 3970, 353 3932, 325 0.02 0.0285 0.483 0.3163 1.02 0.965 1.08 0.0217 0.0826 0.793 0.1009 1.02 0.869 1.2 0.123 0.0808 0.129 0.8885 1.13 0.965 1.32 0.0432 0.0823 0.599 0.2223 1.04 0.889 1.23 PRS_PLINK_1.99526231496888e.06 427.8 Sinoatrial node dysfunction (Bradycardia) Both 247 2726 8 circulatory system red 2726, 247 682, 51 683, 62 678, 65 681, 69 0.0909 0.0628 0.148 0.8291 1.1 0.968 1.24 0.181 0.195 0.352 0.4531 1.2 0.818 1.75 0.254 0.192 0.186 0.7298 1.29 0.884 1.88 0.313 0.191 0.101 0.9942 1.37 0.94 1.99 PRS_PLINK_1.99526231496888e.06 427.9 Palpitations Both 2672 28419 8 circulatory system red 28419, 2672 7143, 670 7079, 706 7182, 647 7009, 649 -0.00307 0.0204 0.881 0.05519 0.997 0.958 1.04 0.0607 0.0564 0.282 0.5495 1.06 0.951 1.19 -0.0378 0.0576 0.511 0.2917 0.963 0.86 1.08 -0.01 0.0576 0.862 0.06438 0.99 0.884 1.11 PRS_PLINK_1.99526231496888e.06 428 Congestive heart failure; nonhypertensive Both 2359 36584 8 circulatory system red 36584, 2359 9182, 527 9102, 579 9143, 589 9143, 664 0.0963 0.0205 2.6e-06 5.585 1.1 1.06 1.15 0.109 0.0619 0.0788 1.104 1.12 0.988 1.26 0.118 0.0617 0.0559 1.253 1.13 0.997 1.27 0.241 0.0602 6.1e-05 4.215 1.27 1.13 1.43 PRS_PLINK_1.99526231496888e.06 428.1 Congestive heart failure (CHF) NOS Both 713 13567 8 circulatory system red 13567, 713 3390, 138 3393, 197 3389, 181 3386, 197 0.132 0.0367 0.000336 3.474 1.14 1.06 1.23 0.358 0.113 0.00156 2.806 1.43 1.15 1.78 0.279 0.115 0.0155 1.811 1.32 1.05 1.66 0.36 0.113 0.0015 2.825 1.43 1.15 1.79 PRS_PLINK_1.99526231496888e.06 428.2 Heart failure NOS Both 1894 29081 8 circulatory system red 29081, 1894 7264, 431 7280, 463 7273, 467 7254, 533 0.0846 0.0229 0.000216 3.666 1.09 1.04 1.14 0.077 0.0689 0.263 0.5793 1.08 0.944 1.24 0.0814 0.0688 0.236 0.6266 1.08 0.948 1.24 0.22 0.0669 0.000988 3.005 1.25 1.09 1.42 PRS_PLINK_1.99526231496888e.06 429 Ill-defined descriptions and complications of heart disease Both 462 5073 8 circulatory system red 5073, 462 1276, 108 1266, 110 1262, 119 1268, 125 0.036 0.0482 0.454 0.3428 1.04 0.943 1.14 0.0278 0.141 0.843 0.07408 1.03 0.781 1.35 0.115 0.138 0.406 0.3919 1.12 0.856 1.47 0.163 0.137 0.232 0.6337 1.18 0.901 1.54 PRS_PLINK_1.99526231496888e.06 429.1 Heart transplant/surgery Both 19 447 8 circulatory system red 447, 19 112, 4 112, 7 112, 4 111, 4 -0.138 0.227 0.543 0.2654 0.871 0.558 1.36 0.595 0.575 0.301 0.5215 1.81 0.587 5.6 0.0663 0.625 0.915 0.03839 1.07 0.314 3.63 0.00936 0.686 0.989 0.00475 1.01 0.263 3.87 PRS_PLINK_1.99526231496888e.06 429.2 Abnormal function study of cardiovascular system Both 336 3689 8 circulatory system red 3689, 336 925, 80 921, 86 926, 85 916, 85 -0.0163 0.0579 0.778 0.1091 0.984 0.878 1.1 0.0712 0.161 0.659 0.1812 1.07 0.783 1.47 0.0593 0.161 0.713 0.147 1.06 0.774 1.46 0.0734 0.161 0.649 0.1875 1.08 0.784 1.48 PRS_PLINK_1.99526231496888e.06 429.3 Symptoms involving cardiovascular system Both 126 1424 8 circulatory system red 1424, 126 356, 28 357, 23 355, 35 356, 40 0.194 0.0861 0.0239 1.622 1.21 1.03 1.44 -0.191 0.283 0.499 0.3017 0.826 0.475 1.44 0.249 0.26 0.338 0.4712 1.28 0.771 2.13 0.393 0.254 0.121 0.9159 1.48 0.901 2.44 PRS_PLINK_1.99526231496888e.06 430 Intracranial hemorrhage Both 1172 13327 8 circulatory system red 13327, 1172 3337, 270 3344, 279 3311, 314 3332, 308 0.0642 0.03 0.0322 1.492 1.07 1.01 1.13 0.0327 0.0886 0.712 0.1476 1.03 0.869 1.23 0.16 0.0864 0.0643 1.192 1.17 0.991 1.39 0.136 0.0868 0.118 0.929 1.15 0.966 1.36 PRS_PLINK_1.99526231496888e.06 430.1 Subarachnoid hemorrhage Both 569 6142 8 circulatory system red 6142, 569 1563, 134 1518, 126 1556, 160 1505, 148 0.0902 0.0437 0.0388 1.411 1.09 1 1.19 -0.0367 0.129 0.775 0.1104 0.964 0.749 1.24 0.183 0.122 0.134 0.8729 1.2 0.945 1.52 0.138 0.124 0.267 0.5741 1.15 0.9 1.46 PRS_PLINK_1.99526231496888e.06 430.2 Intracerebral hemorrhage Both 439 5232 8 circulatory system red 5232, 439 1306, 102 1318, 117 1301, 102 1305, 117 0.0238 0.0489 0.627 0.2028 1.02 0.93 1.13 0.128 0.14 0.362 0.4418 1.14 0.864 1.5 0.0174 0.145 0.904 0.04366 1.02 0.766 1.35 0.138 0.14 0.326 0.487 1.15 0.872 1.51 PRS_PLINK_1.99526231496888e.06 430.3 Subdural hemorrhage Both 150 1749 8 circulatory system red 1749, 150 444, 35 434, 36 434, 44 437, 35 0.0426 0.0813 0.6 0.2216 1.04 0.89 1.22 0.0546 0.242 0.821 0.0856 1.06 0.658 1.7 0.226 0.233 0.333 0.4772 1.25 0.793 1.98 0.00621 0.244 0.98 0.008894 1.01 0.623 1.62 PRS_PLINK_1.99526231496888e.06 433 Cerebrovascular disease Both 4755 58932 8 circulatory system red 58932, 4755 14722, 1174 14798, 1192 14675, 1186 14717, 1199 0.0116 0.0149 0.439 0.3573 1.01 0.982 1.04 0.00895 0.0427 0.834 0.07884 1.01 0.928 1.1 0.0141 0.0428 0.741 0.13 1.01 0.933 1.1 0.0243 0.0427 0.569 0.2451 1.02 0.942 1.11 PRS_PLINK_1.99526231496888e.06 433.1 Occlusion and stenosis of precerebral arteries Both 603 7600 8 circulatory system red 7600, 603 1901, 147 1901, 138 1898, 171 1899, 147 0.00645 0.0417 0.877 0.05695 1.01 0.927 1.09 -0.0703 0.122 0.566 0.2473 0.932 0.733 1.18 0.153 0.117 0.19 0.7215 1.17 0.927 1.46 0.00545 0.121 0.964 0.01594 1.01 0.794 1.27 PRS_PLINK_1.99526231496888e.06 433.12 Cerebral atherosclerosis Both 123 1453 8 circulatory system red 1453, 123 365, 29 361, 25 367, 36 359, 33 0.0723 0.0915 0.429 0.3672 1.07 0.899 1.29 -0.134 0.275 0.625 0.2042 0.874 0.51 1.5 0.237 0.257 0.356 0.4491 1.27 0.766 2.1 0.142 0.26 0.585 0.233 1.15 0.693 1.92 PRS_PLINK_1.99526231496888e.06 433.2 Occlusion of cerebral arteries Both 2213 28187 8 circulatory system red 28187, 2213 7083, 535 7029, 574 7030, 549 7034, 552 0.000966 0.0218 0.965 0.01562 1 0.959 1.04 0.0778 0.0623 0.212 0.6737 1.08 0.957 1.22 0.0342 0.063 0.587 0.2313 1.03 0.915 1.17 0.0415 0.063 0.51 0.2925 1.04 0.921 1.18 PRS_PLINK_1.99526231496888e.06 433.21 Cerebral artery occlusion, with cerebral infarction Both 850 11261 8 circulatory system red 11261, 850 2825, 200 2814, 231 2802, 210 2814, 208 -0.00901 0.0351 0.797 0.09831 0.991 0.925 1.06 0.149 0.0998 0.136 0.8656 1.16 0.954 1.41 0.0587 0.102 0.565 0.2479 1.06 0.868 1.3 0.0492 0.102 0.63 0.2004 1.05 0.86 1.28 PRS_PLINK_1.99526231496888e.06 433.3 Cerebral ischemia Both 1585 19448 8 circulatory system red 19448, 1585 4926, 393 4800, 383 4857, 375 4862, 432 0.0345 0.0258 0.181 0.7413 1.04 0.984 1.09 -0.000965 0.0745 0.99 0.004511 0.999 0.863 1.16 -0.0349 0.0749 0.641 0.1932 0.966 0.834 1.12 0.112 0.0726 0.122 0.9145 1.12 0.97 1.29 PRS_PLINK_1.99526231496888e.06 433.31 Transient cerebral ischemia Both 1181 14450 8 circulatory system red 14450, 1181 3676, 291 3558, 287 3605, 279 3610, 323 0.0363 0.0298 0.223 0.6512 1.04 0.978 1.1 0.0149 0.0863 0.863 0.06413 1.02 0.857 1.2 -0.022 0.0869 0.8 0.09704 0.978 0.825 1.16 0.128 0.0842 0.128 0.8912 1.14 0.964 1.34 PRS_PLINK_1.99526231496888e.06 433.5 Cerebral aneurysm Both 260 2923 8 circulatory system red 2923, 260 736, 64 729, 71 728, 63 730, 62 0.0324 0.0661 0.624 0.2045 1.03 0.907 1.18 0.109 0.179 0.544 0.2646 1.11 0.785 1.58 -0.0096 0.183 0.958 0.01855 0.99 0.692 1.42 -0.023 0.184 0.901 0.04548 0.977 0.681 1.4 PRS_PLINK_1.99526231496888e.06 433.8 Late effects of cerebrovascular disease Both 632 8793 8 circulatory system red 8793, 632 2225, 152 2177, 154 2195, 157 2194, 169 0.0571 0.0403 0.156 0.8058 1.06 0.978 1.15 0.0277 0.118 0.814 0.08946 1.03 0.816 1.29 0.0425 0.117 0.717 0.1447 1.04 0.829 1.31 0.125 0.115 0.28 0.5533 1.13 0.904 1.42 PRS_PLINK_1.99526231496888e.06 440 Atherosclerosis Both 602 8853 8 circulatory system red 8853, 602 2230, 145 2198, 144 2214, 166 2208, 147 -0.00347 0.0417 0.934 0.02979 0.997 0.918 1.08 0.00638 0.121 0.958 0.01868 1.01 0.794 1.28 0.152 0.117 0.196 0.7087 1.16 0.925 1.46 0.00925 0.121 0.939 0.02742 1.01 0.797 1.28 PRS_PLINK_1.99526231496888e.06 440.1 Atherosclerosis of renal artery Both 23 734 8 circulatory system red 734, 23 186, 4 182, 2 182, 11 184, 6 0.206 0.192 0.282 0.5495 1.23 0.844 1.79 -0.696 0.698 0.318 0.4973 0.498 0.127 1.96 1.03 0.527 0.0498 1.303 2.81 1 7.9 0.447 0.563 0.428 0.369 1.56 0.518 4.71 PRS_PLINK_1.99526231496888e.06 440.2 Atherosclerosis of the extremities Both 365 5154 8 circulatory system red 5154, 365 1289, 95 1289, 83 1285, 92 1289, 95 -0.00865 0.0528 0.87 0.06054 0.991 0.894 1.1 -0.122 0.154 0.431 0.3657 0.886 0.654 1.2 -0.0269 0.15 0.858 0.06652 0.973 0.725 1.31 -0.0167 0.15 0.911 0.04036 0.983 0.734 1.32 PRS_PLINK_1.99526231496888e.06 440.9 Atherosclerosis of aorta Both 137 1851 8 circulatory system red 1851, 137 462, 32 464, 32 468, 41 456, 32 0.0218 0.0874 0.803 0.09504 1.02 0.861 1.21 -0.00512 0.253 0.984 0.007067 0.995 0.606 1.63 0.219 0.24 0.362 0.4407 1.24 0.777 1.99 0.0257 0.255 0.92 0.03633 1.03 0.623 1.69 PRS_PLINK_1.99526231496888e.06 441 Vascular insufficiency of intestine Both 315 4192 8 circulatory system red 4192, 315 1065, 85 1032, 83 1046, 68 1048, 79 -0.0423 0.0585 0.469 0.3289 0.959 0.855 1.07 0.0101 0.159 0.949 0.02257 1.01 0.739 1.38 -0.195 0.167 0.243 0.6148 0.823 0.593 1.14 -0.033 0.162 0.838 0.07668 0.968 0.705 1.33 PRS_PLINK_1.99526231496888e.06 441.1 Acute vascular insufficiency of intestine Both 140 1944 8 circulatory system red 1944, 140 485, 32 487, 48 486, 28 485, 32 -0.108 0.0898 0.229 0.641 0.897 0.753 1.07 0.399 0.233 0.087 1.061 1.49 0.944 2.35 -0.137 0.261 0.599 0.2226 0.872 0.523 1.45 0.0124 0.253 0.961 0.01724 1.01 0.616 1.66 PRS_PLINK_1.99526231496888e.06 442 Other aneurysm Both 871 12071 8 circulatory system red 12071, 871 3055, 232 2997, 193 3001, 215 3013, 231 0.0314 0.0342 0.358 0.4466 1.03 0.965 1.1 -0.162 0.101 0.107 0.9687 0.851 0.699 1.04 -0.0425 0.0979 0.664 0.1778 0.958 0.791 1.16 0.0282 0.0965 0.77 0.1134 1.03 0.851 1.24 PRS_PLINK_1.99526231496888e.06 442.1 Aortic aneurysm Both 611 9043 8 circulatory system red 9043, 611 2326, 169 2196, 134 2294, 145 2224, 163 0.00552 0.0412 0.893 0.04898 1.01 0.928 1.09 -0.17 0.119 0.153 0.815 0.844 0.668 1.07 -0.134 0.116 0.249 0.6042 0.874 0.696 1.1 0.0375 0.114 0.742 0.1297 1.04 0.831 1.3 PRS_PLINK_1.99526231496888e.06 442.11 Abdominal aortic aneurysm Both 317 5469 8 circulatory system red 5469, 317 1382, 84 1354, 70 1364, 75 1367, 88 0.0211 0.0562 0.707 0.1506 1.02 0.915 1.14 -0.158 0.165 0.338 0.4709 0.854 0.618 1.18 -0.09 0.162 0.579 0.2376 0.914 0.665 1.26 0.0829 0.157 0.597 0.2242 1.09 0.799 1.48 PRS_PLINK_1.99526231496888e.06 442.2 Aneurysm of iliac artery Both 33 605 8 circulatory system red 605, 33 154, 8 149, 5 151, 5 151, 15 0.314 0.16 0.0499 1.301 1.37 1 1.87 -0.341 0.529 0.519 0.2848 0.711 0.252 2.01 -0.413 0.515 0.422 0.3746 0.661 0.241 1.81 0.657 0.432 0.128 0.8911 1.93 0.827 4.5 PRS_PLINK_1.99526231496888e.06 442.3 Aneurysm of artery of lower extremity Both 87 1106 8 circulatory system red 1106, 87 281, 24 272, 16 278, 26 275, 21 0.0206 0.106 0.846 0.07245 1.02 0.829 1.26 -0.328 0.325 0.312 0.5054 0.72 0.381 1.36 0.157 0.291 0.589 0.2298 1.17 0.662 2.07 -0.0663 0.303 0.826 0.08278 0.936 0.517 1.69 PRS_PLINK_1.99526231496888e.06 442.4 Arterial dissection Both 40 411 8 circulatory system red 411, 40 103, 8 103, 6 101, 11 103, 15 0.346 0.145 0.0175 1.758 1.41 1.06 1.88 -0.203 0.514 0.693 0.1594 0.816 0.298 2.23 0.398 0.466 0.393 0.4059 1.49 0.598 3.71 0.523 0.438 0.232 0.6336 1.69 0.715 3.98 PRS_PLINK_1.99526231496888e.06 442.8 Aneurysm of other specified artery Both 121 1440 8 circulatory system red 1440, 121 362, 27 358, 32 370, 40 350, 22 0.0418 0.0903 0.643 0.1915 1.04 0.874 1.24 0.12 0.266 0.653 0.1852 1.13 0.669 1.9 0.373 0.255 0.143 0.8433 1.45 0.881 2.39 -0.17 0.289 0.556 0.255 0.844 0.479 1.49 PRS_PLINK_1.99526231496888e.06 443 Peripheral vascular disease Both 1934 26801 8 circulatory system red 26801, 1934 6713, 478 6685, 473 6701, 495 6694, 488 0.0176 0.0232 0.448 0.3485 1.02 0.972 1.07 -0.00461 0.067 0.945 0.02451 0.995 0.873 1.14 0.0383 0.0663 0.563 0.2493 1.04 0.912 1.18 0.0311 0.0667 0.641 0.1934 1.03 0.905 1.18 PRS_PLINK_1.99526231496888e.06 443.1 Raynaud's syndrome Both 753 8551 8 circulatory system red 8551, 753 2155, 178 2149, 180 2109, 199 2138, 196 0.0498 0.0377 0.186 0.7301 1.05 0.976 1.13 0.0224 0.11 0.838 0.07662 1.02 0.825 1.27 0.129 0.107 0.23 0.6382 1.14 0.922 1.4 0.102 0.108 0.345 0.4618 1.11 0.896 1.37 PRS_PLINK_1.99526231496888e.06 443.7 Peripheral angiopathy in diseases classified elsewhere Both 111 2583 8 circulatory system red 2583, 111 644, 26 647, 24 649, 32 641, 29 0.0593 0.0936 0.526 0.2786 1.06 0.883 1.27 -0.0588 0.281 0.834 0.0787 0.943 0.544 1.64 0.19 0.262 0.468 0.3299 1.21 0.723 2.02 0.099 0.268 0.712 0.1478 1.1 0.653 1.87 PRS_PLINK_1.99526231496888e.06 443.8 Other specified peripheral vascular diseases Both 1857 25181 8 circulatory system red 25181, 1857 6300, 459 6288, 456 6299, 474 6289, 468 0.014 0.0237 0.555 0.256 1.01 0.968 1.06 -0.0028 0.0684 0.967 0.0144 0.997 0.872 1.14 0.0344 0.0678 0.612 0.2135 1.04 0.906 1.18 0.0303 0.0681 0.657 0.1824 1.03 0.902 1.18 PRS_PLINK_1.99526231496888e.06 443.9 Peripheral vascular disease, unspecified Both 1122 16871 8 circulatory system red 16871, 1122 4225, 288 4216, 281 4272, 275 4153, 278 -0.00533 0.0302 0.86 0.06546 0.995 0.937 1.06 -0.0223 0.0864 0.796 0.09913 0.978 0.826 1.16 -0.0582 0.0869 0.503 0.2984 0.943 0.796 1.12 -0.0133 0.0868 0.878 0.05654 0.987 0.832 1.17 PRS_PLINK_1.99526231496888e.06 444 Arterial embolism and thrombosis Both 423 6204 8 circulatory system red 6204, 423 1549, 109 1557, 98 1549, 110 1547, 106 -0.00787 0.0498 0.875 0.05822 0.992 0.9 1.09 -0.11 0.143 0.441 0.3556 0.896 0.677 1.19 0.0152 0.139 0.913 0.03954 1.02 0.773 1.33 -0.0164 0.141 0.907 0.04231 0.984 0.747 1.3 PRS_PLINK_1.99526231496888e.06 444.1 Arterial embolism and thrombosis of lower extremity artery Both 236 3651 8 circulatory system red 3651, 236 916, 54 914, 60 917, 62 902, 60 0.0132 0.0652 0.839 0.07612 1.01 0.892 1.15 0.107 0.191 0.574 0.2408 1.11 0.766 1.62 0.14 0.19 0.461 0.3361 1.15 0.793 1.67 0.119 0.191 0.533 0.2735 1.13 0.775 1.64 PRS_PLINK_1.99526231496888e.06 446 Polyarteritis nodosa and allied conditions Both 395 5738 8 circulatory system red 5738, 395 1434, 78 1434, 102 1434, 103 1435, 112 0.122 0.05 0.0149 1.828 1.13 1.02 1.25 0.26 0.154 0.0912 1.04 1.3 0.959 1.75 0.278 0.153 0.0701 1.154 1.32 0.977 1.78 0.354 0.151 0.019 1.722 1.43 1.06 1.92 PRS_PLINK_1.99526231496888e.06 446.4 Wegener's granulomatosis Both 81 1295 8 circulatory system red 1295, 81 324, 14 324, 20 323, 23 324, 24 0.167 0.103 0.103 0.9865 1.18 0.967 1.45 0.324 0.344 0.346 0.4609 1.38 0.705 2.71 0.504 0.333 0.13 0.8856 1.66 0.862 3.18 0.516 0.33 0.118 0.9276 1.68 0.877 3.2 PRS_PLINK_1.99526231496888e.06 446.5 Giant cell arteritis Both 206 2622 8 circulatory system red 2622, 206 671, 42 645, 55 649, 48 656, 61 0.136 0.0694 0.0493 1.307 1.15 1 1.31 0.318 0.209 0.128 0.8936 1.37 0.913 2.07 0.184 0.215 0.393 0.4061 1.2 0.789 1.83 0.392 0.205 0.0558 1.254 1.48 0.99 2.21 PRS_PLINK_1.99526231496888e.06 446.9 Arteritis NOS Both 106 1715 8 circulatory system red 1715, 106 432, 19 428, 25 433, 29 422, 33 0.128 0.0975 0.189 0.7235 1.14 0.939 1.38 0.257 0.302 0.395 0.4032 1.29 0.715 2.34 0.395 0.293 0.178 0.749 1.48 0.835 2.64 0.578 0.287 0.0445 1.352 1.78 1.01 3.13 PRS_PLINK_1.99526231496888e.06 447 Other disorders of arteries and arterioles Both 621 8868 8 circulatory system red 8868, 621 2216, 170 2214, 151 2239, 150 2194, 150 -0.0441 0.0414 0.286 0.5431 0.957 0.882 1.04 -0.119 0.115 0.301 0.5215 0.888 0.708 1.11 -0.139 0.115 0.227 0.6438 0.87 0.694 1.09 -0.114 0.116 0.325 0.4877 0.893 0.712 1.12 PRS_PLINK_1.99526231496888e.06 447.1 Stricture of artery Both 397 5654 8 circulatory system red 5654, 397 1421, 97 1407, 98 1412, 100 1410, 102 -0.00681 0.0508 0.893 0.04891 0.993 0.899 1.1 0.0316 0.147 0.83 0.08099 1.03 0.774 1.38 0.0309 0.146 0.833 0.07938 1.03 0.774 1.37 0.0554 0.146 0.705 0.152 1.06 0.794 1.41 PRS_PLINK_1.99526231496888e.06 448 Disease of capillaries Both 86 1027 8 circulatory system red 1027, 86 257, 27 258, 17 254, 23 257, 19 0.00776 0.11 0.944 0.02505 1.01 0.812 1.25 -0.479 0.315 0.127 0.8947 0.619 0.334 1.15 -0.147 0.291 0.613 0.2124 0.863 0.488 1.53 -0.339 0.305 0.265 0.5762 0.712 0.392 1.29 PRS_PLINK_1.99526231496888e.06 450 Noninfectious disorders of lymphatic channels Both 381 5156 8 circulatory system red 5156, 381 1291, 89 1291, 84 1287, 107 1287, 101 0.0538 0.0529 0.309 0.5099 1.06 0.951 1.17 -0.0647 0.156 0.678 0.1687 0.937 0.69 1.27 0.199 0.148 0.179 0.7481 1.22 0.913 1.63 0.132 0.15 0.376 0.425 1.14 0.852 1.53 PRS_PLINK_1.99526231496888e.06 451 Phlebitis and thrombophlebitis Both 2252 27957 8 circulatory system red 27957, 2252 7032, 540 6950, 560 6986, 575 6979, 577 0.0346 0.0216 0.11 0.96 1.04 0.992 1.08 0.0493 0.0626 0.431 0.3658 1.05 0.929 1.19 0.0729 0.0622 0.241 0.6171 1.08 0.952 1.22 0.0786 0.0623 0.207 0.684 1.08 0.957 1.22 PRS_PLINK_1.99526231496888e.06 451.2 Phlebitis and thrombophlebitis of lower extremities Both 2088 25960 8 circulatory system red 25960, 2088 6493, 490 6496, 521 6471, 537 6489, 540 0.0443 0.0224 0.0477 1.322 1.05 1 1.09 0.0621 0.0653 0.341 0.4673 1.06 0.936 1.21 0.0977 0.0649 0.132 0.8799 1.1 0.971 1.25 0.102 0.0649 0.115 0.9405 1.11 0.976 1.26 PRS_PLINK_1.99526231496888e.06 452 Other venous embolism and thrombosis Both 305 4118 8 circulatory system red 4118, 305 1035, 79 1027, 82 1023, 70 1029, 74 -0.0197 0.0592 0.74 0.1311 0.98 0.873 1.1 0.0455 0.163 0.78 0.1081 1.05 0.761 1.44 -0.0972 0.169 0.565 0.2483 0.907 0.652 1.26 -0.0638 0.167 0.702 0.1539 0.938 0.677 1.3 PRS_PLINK_1.99526231496888e.06 454 Varicose veins Both 8006 83774 8 circulatory system red 83774, 8006 21073, 1992 20910, 1994 20875, 2006 20888, 2014 0.00696 0.0117 0.551 0.2589 1.01 0.984 1.03 0.00893 0.0331 0.788 0.1036 1.01 0.946 1.08 0.0173 0.0331 0.601 0.2213 1.02 0.954 1.09 0.023 0.0331 0.487 0.3129 1.02 0.959 1.09 PRS_PLINK_1.99526231496888e.06 454.1 Varicose veins of lower extremity Both 8287 85950 8 circulatory system red 85950, 8287 21612, 2082 21480, 2064 21761, 2102 21071, 2038 0.00239 0.0115 0.835 0.07818 1 0.98 1.03 -0.0024 0.0325 0.941 0.02631 0.998 0.936 1.06 0.00373 0.0324 0.908 0.0418 1 0.942 1.07 0.00703 0.0327 0.83 0.08114 1.01 0.945 1.07 PRS_PLINK_1.99526231496888e.06 454.11 Varicose veins of lower extremity, symptomtic Both 338 4442 8 circulatory system red 4442, 338 1121, 92 1103, 91 1106, 87 1111, 68 -0.118 0.0582 0.043 1.366 0.889 0.793 0.996 0.00137 0.153 0.993 0.003129 1 0.742 1.35 -0.0366 0.154 0.812 0.09023 0.964 0.713 1.3 -0.288 0.165 0.0804 1.095 0.75 0.543 1.04 PRS_PLINK_1.99526231496888e.06 455 Hemorrhoids Both 16487 171594 8 circulatory system red 171594, 16487 42947, 4114 42928, 4115 43200, 4046 42465, 4207 0.0102 0.00812 0.21 0.6777 1.01 0.994 1.03 0.00053 0.0231 0.982 0.008034 1 0.956 1.05 -0.0231 0.0232 0.32 0.4951 0.977 0.934 1.02 0.0361 0.023 0.117 0.9326 1.04 0.991 1.08 PRS_PLINK_1.99526231496888e.06 456 Chronic venous insufficiency [CVI] Both 85 1265 8 circulatory system red 1265, 85 322, 18 311, 21 319, 21 313, 25 0.0981 0.106 0.357 0.4478 1.1 0.895 1.36 0.169 0.32 0.599 0.2228 1.18 0.632 2.22 0.131 0.32 0.682 0.166 1.14 0.609 2.13 0.347 0.313 0.267 0.5732 1.41 0.767 2.61 PRS_PLINK_1.99526231496888e.06 457 Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin Both 69 663 8 circulatory system red 663, 69 165, 11 167, 21 164, 19 166, 18 0.0323 0.126 0.798 0.09813 1.03 0.807 1.32 0.598 0.378 0.113 0.946 1.82 0.868 3.81 0.499 0.38 0.188 0.725 1.65 0.783 3.47 0.384 0.386 0.32 0.4953 1.47 0.689 3.13 PRS_PLINK_1.99526231496888e.06 458 Hypotension Both 3122 40224 8 circulatory system red 40224, 3122 10087, 763 10038, 765 10069, 782 10017, 811 0.0352 0.0184 0.0553 1.257 1.04 0.999 1.07 0.00822 0.053 0.877 0.05706 1.01 0.909 1.12 0.0305 0.0528 0.563 0.2494 1.03 0.93 1.14 0.0775 0.0525 0.139 0.8561 1.08 0.975 1.2 PRS_PLINK_1.99526231496888e.06 458.1 Orthostatic hypotension Both 676 8957 8 circulatory system red 8957, 676 2285, 177 2193, 160 2264, 177 2210, 162 0.00581 0.0392 0.882 0.05453 1.01 0.932 1.09 -0.054 0.113 0.632 0.1992 0.947 0.76 1.18 0.0133 0.11 0.904 0.04379 1.01 0.817 1.26 -0.0525 0.113 0.641 0.1932 0.949 0.761 1.18 PRS_PLINK_1.99526231496888e.06 458.2 Iatrogenic hypotension Both 118 1585 8 circulatory system red 1585, 118 396, 30 396, 26 399, 28 393, 34 0.11 0.093 0.237 0.6261 1.12 0.93 1.34 -0.0986 0.272 0.717 0.1446 0.906 0.532 1.54 -0.0695 0.265 0.793 0.1005 0.933 0.555 1.57 0.153 0.258 0.552 0.2577 1.17 0.703 1.93 PRS_PLINK_1.99526231496888e.06 458.9 Hypotension NOS Both 1883 24554 8 circulatory system red 24554, 1883 6150, 449 6158, 475 6105, 462 6134, 497 0.0302 0.0238 0.203 0.6919 1.03 0.984 1.08 0.0555 0.0682 0.416 0.3811 1.06 0.925 1.21 0.0392 0.0687 0.568 0.2457 1.04 0.909 1.19 0.119 0.0676 0.0787 1.104 1.13 0.986 1.29 PRS_PLINK_1.99526231496888e.06 459 Other disorders of circulatory system Both 8927 112673 8 circulatory system red 112673, 8927 28218, 2172 28182, 2249 28111, 2229 28128, 2274 0.0234 0.0109 0.0316 1.501 1.02 1 1.05 0.0376 0.0312 0.229 0.6407 1.04 0.977 1.1 0.0329 0.0313 0.293 0.5325 1.03 0.972 1.1 0.0528 0.0312 0.0906 1.043 1.05 0.992 1.12 PRS_PLINK_1.99526231496888e.06 459.1 Hemorrhage NOS Both 74 993 8 circulatory system red 993, 74 251, 13 247, 29 249, 14 246, 18 -0.0228 0.116 0.844 0.07352 0.977 0.778 1.23 0.811 0.335 0.0154 1.814 2.25 1.17 4.34 0.0518 0.378 0.891 0.05013 1.05 0.502 2.21 0.327 0.358 0.36 0.4437 1.39 0.688 2.8 PRS_PLINK_1.99526231496888e.06 459.9 Circulatory disease NEC Both 8849 111669 8 circulatory system red 111669, 8849 27966, 2147 27937, 2231 27880, 2212 27852, 2256 0.0248 0.0109 0.0228 1.641 1.03 1 1.05 0.0409 0.0314 0.193 0.7152 1.04 0.98 1.11 0.036 0.0315 0.252 0.598 1.04 0.975 1.1 0.0574 0.0314 0.0671 1.173 1.06 0.996 1.13 PRS_PLINK_1.99526231496888e.06 464 Acute sinusitis Both 131 1476 9 respiratory coral4 1476, 131 370, 26 372, 34 366, 31 368, 40 0.103 0.0893 0.25 0.6013 1.11 0.93 1.32 0.253 0.265 0.34 0.469 1.29 0.766 2.17 0.168 0.27 0.532 0.2737 1.18 0.698 2.01 0.452 0.259 0.0807 1.093 1.57 0.946 2.61 PRS_PLINK_1.99526231496888e.06 465 Acute upper respiratory infections of multiple or unspecified sites Both 1510 16828 9 respiratory coral4 16828, 1510 4219, 375 4209, 381 4275, 379 4122, 375 0.0107 0.0268 0.689 0.1616 1.01 0.959 1.07 0.018 0.0758 0.813 0.09011 1.02 0.878 1.18 -0.00336 0.076 0.965 0.01558 0.997 0.859 1.16 0.0287 0.0762 0.706 0.1513 1.03 0.886 1.19 PRS_PLINK_1.99526231496888e.06 465.2 Acute pharyngitis Both 553 6196 9 respiratory coral4 6196, 553 1550, 139 1547, 127 1558, 134 1539, 153 0.0508 0.0441 0.25 0.6024 1.05 0.965 1.15 -0.0822 0.127 0.518 0.2853 0.921 0.718 1.18 -0.0522 0.126 0.679 0.1684 0.949 0.742 1.21 0.102 0.122 0.404 0.3941 1.11 0.872 1.41 PRS_PLINK_1.99526231496888e.06 465.4 Acute laryngitis and tracheitis Both 110 1204 9 respiratory coral4 1204, 110 306, 34 300, 17 303, 33 295, 26 0.0181 0.0965 0.851 0.06995 1.02 0.843 1.23 -0.687 0.3 0.0221 1.655 0.503 0.28 0.906 -0.0155 0.254 0.951 0.02165 0.985 0.598 1.62 -0.237 0.268 0.375 0.4254 0.789 0.467 1.33 PRS_PLINK_1.99526231496888e.06 470 Septal Deviations/Turbinate Hypertrophy Both 3440 34890 9 respiratory coral4 34890, 3440 8779, 795 8707, 870 8790, 843 8609, 929 0.046 0.0175 0.00872 2.059 1.05 1.01 1.08 0.0982 0.0513 0.0556 1.255 1.1 0.998 1.22 0.058 0.0517 0.262 0.5822 1.06 0.958 1.17 0.179 0.0507 0.000424 3.373 1.2 1.08 1.32 PRS_PLINK_1.99526231496888e.06 471 Nasal polyps Both 2359 23487 9 respiratory coral4 23487, 2359 5885, 562 5857, 597 5867, 587 5872, 610 0.0275 0.0213 0.196 0.7071 1.03 0.986 1.07 0.0676 0.0615 0.272 0.5653 1.07 0.948 1.21 0.0468 0.0618 0.449 0.3476 1.05 0.928 1.18 0.0872 0.0613 0.155 0.8099 1.09 0.968 1.23 PRS_PLINK_1.99526231496888e.06 472 Chronic pharyngitis and nasopharyngitis Both 694 7120 9 respiratory coral4 7120, 694 1788, 168 1772, 171 1779, 167 1779, 188 0.0609 0.0389 0.118 0.9281 1.06 0.985 1.15 0.0212 0.113 0.851 0.06983 1.02 0.818 1.28 -0.00149 0.114 0.99 0.004566 0.999 0.799 1.25 0.128 0.111 0.249 0.6043 1.14 0.914 1.41 PRS_PLINK_1.99526231496888e.06 473 Diseases of the larynx and vocal cords Both 1688 18166 9 respiratory coral4 18166, 1688 4548, 409 4544, 407 4543, 444 4526, 428 0.0173 0.0252 0.491 0.3085 1.02 0.968 1.07 -0.00268 0.073 0.971 0.01293 0.997 0.864 1.15 0.0822 0.0716 0.251 0.6005 1.09 0.944 1.25 0.0539 0.0723 0.456 0.3411 1.06 0.916 1.22 PRS_PLINK_1.99526231496888e.06 473.1 Chronic laryngitis Both 64 747 9 respiratory coral4 747, 64 192, 15 182, 12 188, 27 185, 10 -0.0252 0.129 0.845 0.07299 0.975 0.757 1.26 -0.134 0.38 0.724 0.1404 0.874 0.415 1.84 0.583 0.327 0.0751 1.125 1.79 0.943 3.4 -0.388 0.408 0.341 0.4672 0.678 0.305 1.51 PRS_PLINK_1.99526231496888e.06 473.3 Paralysis/spasm of vocal cords or larynx Both 172 1889 9 respiratory coral4 1889, 172 474, 40 471, 38 473, 46 471, 48 0.0644 0.0778 0.408 0.3895 1.07 0.916 1.24 -0.0796 0.234 0.733 0.1347 0.923 0.584 1.46 0.173 0.224 0.438 0.3582 1.19 0.767 1.84 0.222 0.222 0.318 0.4977 1.25 0.807 1.93 PRS_PLINK_1.99526231496888e.06 473.4 Voice disturbance Both 706 7600 9 respiratory coral4 7600, 706 1906, 174 1893, 187 1928, 171 1871, 174 -0.004 0.0393 0.919 0.03673 0.996 0.922 1.08 0.086 0.11 0.434 0.3629 1.09 0.879 1.35 -0.035 0.112 0.755 0.122 0.966 0.775 1.2 0.0258 0.112 0.817 0.08756 1.03 0.824 1.28 PRS_PLINK_1.99526231496888e.06 474 Acute and chronic tonsillitis Both 1361 14138 9 respiratory coral4 14138, 1361 3550, 328 3538, 340 3525, 358 3521, 335 0.0241 0.0283 0.396 0.4027 1.02 0.969 1.08 0.0376 0.0808 0.641 0.1929 1.04 0.886 1.22 0.0946 0.0799 0.237 0.6261 1.1 0.94 1.29 0.0303 0.0811 0.709 0.1493 1.03 0.879 1.21 PRS_PLINK_1.99526231496888e.06 474.1 Acute tonsillitis Both 426 4455 9 respiratory coral4 4455, 426 1127, 96 1115, 110 1101, 104 1110, 116 0.0846 0.05 0.0904 1.044 1.09 0.987 1.2 0.149 0.145 0.304 0.5166 1.16 0.873 1.54 0.104 0.147 0.477 0.3217 1.11 0.833 1.48 0.2 0.144 0.163 0.7878 1.22 0.922 1.62 PRS_PLINK_1.99526231496888e.06 474.2 Chronic tonsillitis and adenoiditis Both 868 8975 9 respiratory coral4 8975, 868 2266, 221 2227, 220 2234, 230 2244, 196 -0.023 0.036 0.523 0.2815 0.977 0.911 1.05 0.015 0.0995 0.88 0.05539 1.02 0.835 1.23 0.0494 0.0986 0.616 0.2103 1.05 0.866 1.27 -0.107 0.102 0.295 0.5307 0.898 0.735 1.1 PRS_PLINK_1.99526231496888e.06 475 Chronic sinusitis Both 1842 19122 9 respiratory coral4 19122, 1842 4797, 475 4768, 453 4851, 460 4702, 454 -0.00274 0.0245 0.911 0.04042 0.997 0.95 1.05 -0.0416 0.0687 0.545 0.2635 0.959 0.838 1.1 -0.0406 0.0684 0.553 0.2575 0.96 0.84 1.1 -0.0221 0.0688 0.747 0.1264 0.978 0.855 1.12 PRS_PLINK_1.99526231496888e.06 476 Allergic rhinitis Both 804 7930 9 respiratory coral4 7930, 804 1982, 223 1999, 199 1985, 186 1962, 196 -0.0486 0.038 0.201 0.6974 0.953 0.884 1.03 -0.122 0.102 0.231 0.6361 0.885 0.724 1.08 -0.183 0.104 0.0791 1.102 0.833 0.68 1.02 -0.114 0.103 0.267 0.5731 0.892 0.729 1.09 PRS_PLINK_1.99526231496888e.06 477 Epistaxis or throat hemorrhage Both 1468 16711 9 respiratory coral4 16711, 1468 4178, 377 4193, 382 4161, 355 4175, 354 -0.0066 0.027 0.807 0.09324 0.993 0.942 1.05 0.00942 0.0757 0.901 0.04529 1.01 0.87 1.17 -0.0496 0.0771 0.52 0.2843 0.952 0.818 1.11 -0.0525 0.0772 0.496 0.3043 0.949 0.816 1.1 PRS_PLINK_1.99526231496888e.06 478 Throat pain Both 269 2775 9 respiratory coral4 2775, 269 696, 62 692, 65 698, 60 689, 82 0.0987 0.0619 0.111 0.9544 1.1 0.978 1.25 0.0453 0.184 0.805 0.09406 1.05 0.73 1.5 -0.0367 0.187 0.844 0.07366 0.964 0.669 1.39 0.277 0.176 0.115 0.9409 1.32 0.935 1.86 PRS_PLINK_1.99526231496888e.06 479 Other upper respiratory disease Both 2863 29922 9 respiratory coral4 29922, 2863 7549, 703 7446, 709 7586, 717 7335, 732 0.0235 0.0194 0.227 0.6447 1.02 0.986 1.06 0.0225 0.0556 0.686 0.1638 1.02 0.917 1.14 0.0164 0.0555 0.768 0.1147 1.02 0.912 1.13 0.0695 0.0553 0.209 0.68 1.07 0.962 1.19 PRS_PLINK_1.99526231496888e.06 480 Pneumonia Both 5640 71497 9 respiratory coral4 71497, 5640 17863, 1315 17944, 1405 17814, 1478 17849, 1441 0.0371 0.0136 0.00634 2.198 1.04 1.01 1.07 0.0625 0.0398 0.116 0.9349 1.06 0.985 1.15 0.121 0.0393 0.00212 2.673 1.13 1.04 1.22 0.0963 0.0396 0.0151 1.822 1.1 1.02 1.19 PRS_PLINK_1.99526231496888e.06 480.1 Bacterial pneumonia Both 3627 46061 9 respiratory coral4 46061, 3627 11550, 842 11472, 881 11534, 961 11487, 943 0.0495 0.0169 0.00329 2.482 1.05 1.02 1.09 0.054 0.0499 0.279 0.5536 1.06 0.957 1.16 0.136 0.049 0.00546 2.263 1.15 1.04 1.26 0.124 0.0492 0.0115 1.94 1.13 1.03 1.25 PRS_PLINK_1.99526231496888e.06 480.11 Pneumococcal pneumonia Both 3210 40833 9 respiratory coral4 40833, 3210 10245, 742 10192, 786 10211, 849 10170, 833 0.0491 0.0179 0.00621 2.207 1.05 1.01 1.09 0.0653 0.053 0.218 0.6617 1.07 0.962 1.18 0.142 0.0521 0.00657 2.183 1.15 1.04 1.28 0.129 0.0524 0.0142 1.847 1.14 1.03 1.26 PRS_PLINK_1.99526231496888e.06 480.12 Pseudomonal pneumonia Both 46 634 9 respiratory coral4 634, 46 159, 16 158, 3 158, 16 159, 11 0.0137 0.145 0.924 0.03413 1.01 0.763 1.35 -1.4 0.563 0.0128 1.894 0.246 0.0815 0.742 0.0088 0.356 0.98 0.00865 1.01 0.502 2.03 -0.387 0.39 0.321 0.4928 0.679 0.316 1.46 PRS_PLINK_1.99526231496888e.06 480.2 Viral pneumonia Both 39 522 9 respiratory coral4 522, 39 134, 11 127, 11 130, 10 131, 7 -0.254 0.175 0.148 0.8299 0.776 0.55 1.09 0.128 0.424 0.763 0.1173 1.14 0.495 2.61 -0.0129 0.432 0.976 0.01046 0.987 0.423 2.3 -0.345 0.462 0.455 0.3424 0.708 0.286 1.75 PRS_PLINK_1.99526231496888e.06 480.3 Pneumonia due to fungus (mycoses) Both 42 678 9 respiratory coral4 678, 42 173, 11 166, 6 172, 12 167, 13 0.187 0.145 0.197 0.7062 1.21 0.908 1.6 -0.562 0.471 0.233 0.6322 0.57 0.227 1.44 0.0153 0.411 0.97 0.01306 1.02 0.454 2.27 0.35 0.411 0.395 0.4035 1.42 0.634 3.18 PRS_PLINK_1.99526231496888e.06 480.5 Bronchopneumonia and lung abscess Both 423 5257 9 respiratory coral4 5257, 423 1330, 100 1298, 115 1314, 103 1314, 105 0.00389 0.0502 0.938 0.02772 1 0.91 1.11 0.163 0.141 0.25 0.6012 1.18 0.892 1.55 0.0432 0.145 0.765 0.1161 1.04 0.786 1.39 0.0557 0.145 0.7 0.1546 1.06 0.796 1.4 PRS_PLINK_1.99526231496888e.06 481 Influenza Both 191 2422 9 respiratory coral4 2422, 191 610, 53 611, 38 601, 49 600, 50 0.00883 0.0747 0.906 0.04294 1.01 0.871 1.17 -0.327 0.217 0.132 0.88 0.721 0.471 1.1 -0.0716 0.204 0.725 0.1396 0.931 0.624 1.39 -0.0431 0.203 0.832 0.07988 0.958 0.643 1.43 PRS_PLINK_1.99526231496888e.06 483 Acute bronchitis and bronchiolitis Both 116 1405 9 respiratory coral4 1405, 116 350, 28 354, 25 351, 29 348, 34 0.0388 0.0963 0.687 0.163 1.04 0.861 1.26 -0.132 0.277 0.635 0.1975 0.877 0.509 1.51 0.0277 0.269 0.918 0.03709 1.03 0.606 1.74 0.192 0.26 0.46 0.3368 1.21 0.728 2.02 PRS_PLINK_1.99526231496888e.06 495 Asthma Both 17338 187928 9 respiratory coral4 187928, 17338 47192, 4221 47197, 4341 46511, 4304 46972, 4465 0.0217 0.00791 0.00602 2.22 1.02 1.01 1.04 0.0278 0.0226 0.219 0.6595 1.03 0.984 1.07 0.0322 0.0226 0.155 0.809 1.03 0.988 1.08 0.0618 0.0225 0.00598 2.224 1.06 1.02 1.11 PRS_PLINK_1.99526231496888e.06 495.2 Asthma with exacerbation Both 164 1912 9 respiratory coral4 1912, 164 481, 36 474, 52 478, 36 478, 40 0.00203 0.0812 0.98 0.008736 1 0.855 1.17 0.378 0.223 0.0895 1.048 1.46 0.943 2.26 0.0128 0.241 0.958 0.01882 1.01 0.632 1.62 0.103 0.236 0.661 0.1795 1.11 0.699 1.76 PRS_PLINK_1.99526231496888e.06 496 Chronic airway obstruction Both 5308 69214 9 respiratory coral4 69214, 5308 17585, 1275 17130, 1253 17173, 1426 17304, 1351 0.035 0.014 0.0125 1.904 1.04 1.01 1.06 0.00873 0.0412 0.832 0.07978 1.01 0.931 1.09 0.134 0.04 0.000817 3.088 1.14 1.06 1.24 0.0707 0.0405 0.0811 1.091 1.07 0.991 1.16 PRS_PLINK_1.99526231496888e.06 496.1 Emphysema Both 851 11564 9 respiratory coral4 11564, 851 2916, 207 2885, 193 2876, 225 2883, 226 0.0451 0.0348 0.196 0.7088 1.05 0.977 1.12 -0.0576 0.103 0.576 0.2392 0.944 0.771 1.16 0.0965 0.0996 0.333 0.4781 1.1 0.906 1.34 0.0949 0.0995 0.341 0.4678 1.1 0.905 1.34 PRS_PLINK_1.99526231496888e.06 496.2 Chronic bronchitis Both 1317 19655 9 respiratory coral4 19655, 1317 4927, 320 4920, 301 4893, 389 4909, 307 0.0301 0.0279 0.281 0.551 1.03 0.976 1.09 -0.0569 0.0826 0.491 0.3088 0.945 0.803 1.11 0.205 0.078 0.00861 2.065 1.23 1.05 1.43 -0.0439 0.0824 0.594 0.2261 0.957 0.814 1.12 PRS_PLINK_1.99526231496888e.06 496.21 Obstructive chronic bronchitis Both 1184 17996 9 respiratory coral4 17996, 1184 4502, 285 4520, 271 4477, 351 4492, 277 0.03 0.0294 0.308 0.5117 1.03 0.973 1.09 -0.0523 0.0872 0.549 0.2603 0.949 0.8 1.13 0.219 0.0824 0.00798 2.098 1.24 1.06 1.46 -0.0342 0.0869 0.694 0.1588 0.966 0.815 1.15 PRS_PLINK_1.99526231496888e.06 496.3 Bronchiectasis Both 1112 13006 9 respiratory coral4 13006, 1112 3289, 275 3222, 283 3318, 299 3173, 255 -0.015 0.031 0.628 0.2023 0.985 0.927 1.05 0.0563 0.0881 0.523 0.2817 1.06 0.89 1.26 0.0764 0.0871 0.38 0.42 1.08 0.91 1.28 -0.0304 0.0905 0.737 0.1326 0.97 0.812 1.16 PRS_PLINK_1.99526231496888e.06 497 Bronchitis Both 345 4518 9 respiratory coral4 4518, 345 1138, 79 1127, 94 1144, 95 1108, 77 0.00675 0.0569 0.906 0.04309 1.01 0.901 1.13 0.191 0.157 0.226 0.6468 1.21 0.889 1.65 0.184 0.157 0.241 0.6183 1.2 0.884 1.64 0.0178 0.165 0.914 0.03902 1.02 0.737 1.41 PRS_PLINK_1.99526231496888e.06 500 Lung disease due to external agents Both 190 2563 9 respiratory coral4 2563, 190 655, 46 628, 57 639, 42 641, 45 0.00508 0.0722 0.944 0.02511 1.01 0.873 1.16 0.254 0.203 0.211 0.6764 1.29 0.866 1.92 -0.0748 0.217 0.73 0.1366 0.928 0.607 1.42 -0.00654 0.214 0.976 0.0107 0.993 0.653 1.51 PRS_PLINK_1.99526231496888e.06 500.1 Extrinsic allergic alveolitis Both 37 557 9 respiratory coral4 557, 37 141, 5 138, 12 139, 8 139, 12 0.111 0.16 0.488 0.3117 1.12 0.817 1.53 0.837 0.495 0.0905 1.043 2.31 0.876 6.09 0.474 0.528 0.369 0.4327 1.61 0.571 4.52 0.853 0.501 0.0882 1.054 2.35 0.88 6.26 PRS_PLINK_1.99526231496888e.06 500.2 Pneumoconiosis Both 105 1418 9 respiratory coral4 1418, 105 359, 31 350, 31 357, 19 352, 24 -0.0793 0.0989 0.423 0.374 0.924 0.761 1.12 0.0215 0.26 0.934 0.02953 1.02 0.613 1.7 -0.467 0.291 0.109 0.9627 0.627 0.354 1.11 -0.208 0.275 0.45 0.3468 0.812 0.473 1.39 PRS_PLINK_1.99526231496888e.06 501 Pneumonitis due to inhalation of food or vomitus Both 319 4401 9 respiratory coral4 4401, 319 1118, 88 1082, 71 1108, 84 1092, 76 -0.00773 0.058 0.894 0.04868 0.992 0.886 1.11 -0.177 0.164 0.279 0.5539 0.838 0.608 1.15 -0.0323 0.157 0.837 0.07702 0.968 0.711 1.32 -0.11 0.162 0.496 0.3049 0.896 0.652 1.23 PRS_PLINK_1.99526231496888e.06 502 Postinflammatory pulmonary fibrosis Both 411 6032 9 respiratory coral4 6032, 411 1513, 94 1497, 98 1529, 112 1487, 107 0.0782 0.0494 0.114 0.9447 1.08 0.981 1.19 0.0474 0.148 0.749 0.1257 1.05 0.785 1.4 0.163 0.144 0.255 0.5932 1.18 0.889 1.56 0.141 0.145 0.332 0.4793 1.15 0.866 1.53 PRS_PLINK_1.99526231496888e.06 503 Pulmonary congestion and hypostasis Both 188 3519 9 respiratory coral4 3519, 188 879, 49 886, 46 873, 54 880, 39 -0.051 0.0748 0.495 0.3053 0.95 0.821 1.1 -0.069 0.207 0.739 0.1313 0.933 0.622 1.4 0.11 0.2 0.582 0.2351 1.12 0.755 1.65 -0.235 0.216 0.276 0.5583 0.791 0.518 1.21 PRS_PLINK_1.99526231496888e.06 504 Other alveolar and parietoalveolar pneumonopathy Both 142 2260 9 respiratory coral4 2260, 142 563, 30 572, 26 560, 42 562, 44 0.212 0.0826 0.0103 1.986 1.24 1.05 1.45 -0.135 0.266 0.611 0.2136 0.873 0.518 1.47 0.359 0.241 0.137 0.8641 1.43 0.892 2.3 0.375 0.239 0.116 0.9361 1.46 0.912 2.32 PRS_PLINK_1.99526231496888e.06 505 Other pulmonary inflamation or edema Both 34 435 9 respiratory coral4 435, 34 111, 8 107, 2 108, 17 109, 7 0.0809 0.174 0.642 0.1927 1.08 0.771 1.52 -1.11 0.659 0.0912 1.04 0.329 0.0903 1.2 0.748 0.424 0.0779 1.109 2.11 0.92 4.85 -0.133 0.492 0.786 0.1044 0.875 0.334 2.29 PRS_PLINK_1.99526231496888e.06 506 Empyema and pneumothorax Both 651 8026 9 respiratory coral4 8026, 651 2004, 154 2010, 156 2009, 160 2000, 181 0.0658 0.0397 0.0977 1.01 1.07 0.988 1.15 0.00888 0.117 0.94 0.02703 1.01 0.802 1.27 0.0376 0.117 0.748 0.1263 1.04 0.826 1.31 0.162 0.114 0.154 0.8127 1.18 0.941 1.47 PRS_PLINK_1.99526231496888e.06 507 Pleurisy; pleural effusion Both 3569 43880 9 respiratory coral4 43880, 3569 10991, 873 10954, 879 10968, 917 10954, 899 0.0172 0.0172 0.316 0.5002 1.02 0.984 1.05 0.0104 0.0496 0.833 0.07923 1.01 0.917 1.11 0.0551 0.0492 0.262 0.5812 1.06 0.96 1.16 0.0343 0.0495 0.488 0.3117 1.03 0.939 1.14 PRS_PLINK_1.99526231496888e.06 508 Pulmonary collapse; interstitial and compensatory emphysema Both 1123 13891 9 respiratory coral4 13891, 1123 3469, 279 3470, 265 3490, 297 3455, 282 0.0111 0.0309 0.72 0.1428 1.01 0.952 1.07 -0.0477 0.0889 0.592 0.228 0.953 0.801 1.13 0.0574 0.0866 0.507 0.2947 1.06 0.894 1.26 0.0183 0.0877 0.835 0.07821 1.02 0.858 1.21 PRS_PLINK_1.99526231496888e.06 509 Respiratory failure, insufficiency, arrest Both 1185 17527 9 respiratory coral4 17527, 1185 4393, 276 4373, 279 4381, 317 4372, 313 0.0558 0.0292 0.0563 1.25 1.06 0.999 1.12 0.0161 0.0873 0.854 0.06868 1.02 0.856 1.21 0.142 0.0849 0.0951 1.022 1.15 0.976 1.36 0.136 0.0854 0.11 0.9587 1.15 0.97 1.36 PRS_PLINK_1.99526231496888e.06 509.1 Respiratory failure Both 923 13859 9 respiratory coral4 13859, 923 3464, 199 3477, 219 3451, 256 3460, 249 0.0927 0.0329 0.00484 2.315 1.1 1.03 1.17 0.0918 0.1 0.361 0.4428 1.1 0.9 1.33 0.258 0.0972 0.00795 2.099 1.29 1.07 1.57 0.225 0.0981 0.022 1.657 1.25 1.03 1.52 PRS_PLINK_1.99526231496888e.06 509.2 Respiratory insufficiency Both 807 12198 9 respiratory coral4 12198, 807 3075, 178 3024, 181 3051, 226 3042, 222 0.1 0.0351 0.00422 2.375 1.11 1.03 1.18 0.0282 0.108 0.794 0.09999 1.03 0.832 1.27 0.247 0.103 0.0167 1.776 1.28 1.05 1.57 0.233 0.104 0.0246 1.61 1.26 1.03 1.55 PRS_PLINK_1.99526231496888e.06 509.5 Respiratory arrest Both 74 1008 9 respiratory coral4 1008, 74 260, 19 244, 14 252, 19 252, 22 0.0593 0.115 0.607 0.217 1.06 0.847 1.33 -0.226 0.349 0.516 0.2869 0.797 0.403 1.58 0.0267 0.324 0.934 0.02953 1.03 0.544 1.94 0.18 0.318 0.571 0.2435 1.2 0.642 2.24 PRS_PLINK_1.99526231496888e.06 509.8 Dependence on respirator [Ventilator] or supplemental oxygen Both 184 2579 9 respiratory coral4 2579, 184 656, 54 638, 45 640, 43 645, 42 -0.0669 0.0761 0.379 0.4212 0.935 0.806 1.09 -0.16 0.207 0.439 0.3578 0.852 0.569 1.28 -0.215 0.209 0.304 0.5168 0.806 0.535 1.22 -0.223 0.21 0.29 0.5371 0.8 0.53 1.21 PRS_PLINK_1.99526231496888e.06 510 Other diseases of lung Both 432 5174 9 respiratory coral4 5174, 432 1296, 97 1288, 94 1294, 118 1293, 123 0.108 0.049 0.0271 1.567 1.11 1.01 1.23 -0.026 0.149 0.861 0.06475 0.974 0.728 1.3 0.179 0.142 0.208 0.6812 1.2 0.905 1.58 0.257 0.141 0.0677 1.169 1.29 0.981 1.71 PRS_PLINK_1.99526231496888e.06 512 Other symptoms of respiratory system Both 5300 64335 9 respiratory coral4 64335, 5300 16135, 1249 16014, 1262 16123, 1381 16042, 1407 0.0618 0.014 1.04e-05 4.984 1.06 1.03 1.09 0.0162 0.0414 0.695 0.1578 1.02 0.937 1.1 0.103 0.0406 0.0111 1.955 1.11 1.02 1.2 0.131 0.0405 0.00126 2.898 1.14 1.05 1.23 PRS_PLINK_1.99526231496888e.06 512.1 Wheezing Both 126 1550 9 respiratory coral4 1550, 126 388, 31 387, 33 390, 31 385, 31 -0.0152 0.0935 0.871 0.06013 0.985 0.82 1.18 0.0615 0.254 0.809 0.09209 1.06 0.646 1.75 0.00233 0.258 0.993 0.003148 1 0.605 1.66 -0.0031 0.258 0.99 0.004181 0.997 0.601 1.65 PRS_PLINK_1.99526231496888e.06 512.2 Painful respiration Both 140 1523 9 respiratory coral4 1523, 140 381, 23 387, 36 374, 42 381, 39 0.17 0.0876 0.0519 1.285 1.19 0.999 1.41 0.42 0.269 0.119 0.9245 1.52 0.898 2.58 0.604 0.263 0.0215 1.668 1.83 1.09 3.06 0.522 0.267 0.0504 1.298 1.69 0.999 2.85 PRS_PLINK_1.99526231496888e.06 512.7 Shortness of breath Both 3323 41531 9 respiratory coral4 41531, 3323 10400, 791 10354, 800 10413, 850 10352, 882 0.055 0.0177 0.0019 2.72 1.06 1.02 1.09 0.0132 0.052 0.799 0.09728 1.01 0.915 1.12 0.0744 0.0513 0.147 0.8327 1.08 0.974 1.19 0.12 0.0509 0.018 1.744 1.13 1.02 1.25 PRS_PLINK_1.99526231496888e.06 512.8 Cough Both 1711 20522 9 respiratory coral4 20522, 1711 5125, 398 5147, 401 5116, 448 5128, 463 0.0735 0.0246 0.00288 2.541 1.08 1.03 1.13 0.000646 0.0734 0.993 0.003061 1 0.867 1.16 0.121 0.0716 0.0912 1.04 1.13 0.981 1.3 0.159 0.0712 0.0253 1.597 1.17 1.02 1.35 PRS_PLINK_1.99526231496888e.06 512.9 Other dyspnea Both 532 6453 9 respiratory coral4 6453, 532 1612, 119 1622, 132 1623, 144 1593, 137 0.0844 0.0441 0.0554 1.256 1.09 0.998 1.19 0.105 0.131 0.421 0.3755 1.11 0.86 1.43 0.183 0.128 0.154 0.8138 1.2 0.934 1.54 0.15 0.13 0.247 0.6065 1.16 0.901 1.5 PRS_PLINK_1.99526231496888e.06 513 Respiratory abnormalities Both 344 4276 9 respiratory coral4 4276, 344 1086, 76 1053, 84 1068, 103 1067, 81 0.0429 0.0561 0.445 0.3519 1.04 0.935 1.17 0.13 0.163 0.427 0.3698 1.14 0.827 1.57 0.338 0.156 0.0306 1.515 1.4 1.03 1.91 0.067 0.165 0.684 0.1647 1.07 0.774 1.48 PRS_PLINK_1.99526231496888e.06 513.3 Hypoventilation Both 31 572 9 respiratory coral4 572, 31 143, 8 143, 6 144, 8 142, 9 0.11 0.188 0.559 0.2523 1.12 0.772 1.61 -0.265 0.503 0.598 0.2234 0.767 0.286 2.05 0.0629 0.474 0.894 0.04848 1.06 0.421 2.69 -0.0303 0.472 0.949 0.02286 0.97 0.385 2.45 PRS_PLINK_1.99526231496888e.06 513.4 Hyperventilation Both 173 2037 9 respiratory coral4 2037, 173 517, 34 503, 48 509, 54 508, 37 0.0233 0.0791 0.768 0.1147 1.02 0.877 1.2 0.374 0.229 0.103 0.9892 1.45 0.928 2.28 0.494 0.225 0.0284 1.547 1.64 1.05 2.55 0.097 0.242 0.689 0.1621 1.1 0.686 1.77 PRS_PLINK_1.99526231496888e.06 513.8 Disorders of diaphragm Both 94 1002 9 respiratory coral4 1002, 94 256, 23 245, 15 250, 34 250, 22 0.0969 0.105 0.358 0.4459 1.1 0.896 1.35 -0.388 0.336 0.248 0.605 0.678 0.351 1.31 0.404 0.281 0.151 0.8215 1.5 0.863 2.6 -0.117 0.311 0.707 0.1504 0.89 0.483 1.64 PRS_PLINK_1.99526231496888e.06 514 Abnormal findings examination of lungs Both 1360 16815 9 respiratory coral4 16815, 1360 4200, 310 4203, 317 4201, 343 4200, 390 0.0916 0.0273 0.000799 3.098 1.1 1.04 1.16 0.0294 0.0827 0.722 0.1413 1.03 0.876 1.21 0.109 0.0813 0.18 0.7436 1.11 0.951 1.31 0.237 0.0791 0.0027 2.568 1.27 1.09 1.48 PRS_PLINK_1.99526231496888e.06 516 Abnormal sputum Both 1221 14739 9 respiratory coral4 14739, 1221 3715, 279 3655, 294 3691, 333 3674, 315 0.0467 0.0293 0.111 0.9548 1.05 0.989 1.11 0.0702 0.0866 0.417 0.3796 1.07 0.905 1.27 0.185 0.0843 0.0282 1.55 1.2 1.02 1.42 0.135 0.0853 0.112 0.9491 1.15 0.969 1.35 PRS_PLINK_1.99526231496888e.06 516.1 Hemoptysis Both 1196 14347 9 respiratory coral4 14347, 1196 3609, 278 3575, 284 3583, 328 3577, 306 0.0451 0.0296 0.127 0.8955 1.05 0.987 1.11 0.0311 0.0874 0.722 0.1417 1.03 0.869 1.22 0.174 0.0847 0.0397 1.401 1.19 1.01 1.41 0.107 0.086 0.213 0.6714 1.11 0.94 1.32 PRS_PLINK_1.99526231496888e.06 519 Other diseases of respiratory system, not elsewhere classified Both 5349 66112 9 respiratory coral4 66112, 5349 16591, 1259 16511, 1349 16492, 1376 16495, 1363 0.0322 0.014 0.0215 1.667 1.03 1 1.06 0.0735 0.0407 0.0707 1.151 1.08 0.994 1.17 0.0981 0.0405 0.0155 1.811 1.1 1.02 1.19 0.0909 0.0407 0.0253 1.597 1.1 1.01 1.19 PRS_PLINK_1.99526231496888e.06 519.2 Respiratory complications Both 149 2197 9 respiratory coral4 2197, 149 551, 27 547, 41 566, 37 532, 44 0.144 0.0812 0.0767 1.115 1.15 0.985 1.35 0.448 0.25 0.073 1.136 1.56 0.959 2.55 0.294 0.253 0.245 0.6104 1.34 0.817 2.2 0.57 0.248 0.0215 1.669 1.77 1.09 2.87 PRS_PLINK_1.99526231496888e.06 519.8 Other diseases of respiratory system, NEC Both 5049 62577 9 respiratory coral4 62577, 5049 15702, 1200 15649, 1267 15584, 1306 15619, 1274 0.0266 0.0144 0.0647 1.189 1.03 0.998 1.06 0.0568 0.0418 0.174 0.7591 1.06 0.975 1.15 0.0951 0.0416 0.0221 1.656 1.1 1.01 1.19 0.0704 0.0418 0.0927 1.033 1.07 0.988 1.16 PRS_PLINK_1.99526231496888e.06 519.9 Symptoms involving respiratory system and other chest symptoms Both 216 2189 9 respiratory coral4 2189, 216 549, 47 551, 61 543, 43 546, 65 0.0703 0.0705 0.319 0.4963 1.07 0.934 1.23 0.238 0.201 0.236 0.6265 1.27 0.856 1.88 -0.0602 0.216 0.781 0.1074 0.942 0.616 1.44 0.33 0.199 0.097 1.013 1.39 0.942 2.05 PRS_PLINK_1.99526231496888e.06 520 Disorders of tooth development Both 1587 16220 10 digestive chartreuse4 16220, 1587 4159, 402 3990, 400 4046, 360 4023, 425 0.0199 0.026 0.444 0.3527 1.02 0.969 1.07 0.037 0.0739 0.616 0.2102 1.04 0.898 1.2 -0.0835 0.0758 0.271 0.5677 0.92 0.793 1.07 0.0913 0.073 0.211 0.6755 1.1 0.95 1.26 PRS_PLINK_1.99526231496888e.06 520.1 Hereditary disturbances in tooth structure Both 33 402 10 digestive chartreuse4 402, 33 101, 9 100, 11 100, 5 101, 8 -0.0783 0.185 0.672 0.1724 0.925 0.643 1.33 0.146 0.447 0.743 0.1288 1.16 0.482 2.78 -0.537 0.529 0.31 0.5085 0.584 0.207 1.65 -0.0289 0.477 0.952 0.02152 0.971 0.381 2.48 PRS_PLINK_1.99526231496888e.06 520.2 Disturbances in tooth eruption Both 1872 18920 10 digestive chartreuse4 18920, 1872 4820, 483 4640, 478 4784, 434 4674, 477 -0.00444 0.0242 0.854 0.06837 0.996 0.95 1.04 0.0272 0.0676 0.687 0.163 1.03 0.9 1.17 -0.098 0.0691 0.156 0.8059 0.907 0.792 1.04 0.0183 0.0677 0.787 0.1042 1.02 0.892 1.16 PRS_PLINK_1.99526231496888e.06 521 Diseases of hard tissues of teeth Both 1978 22781 10 digestive chartreuse4 22781, 1978 5697, 468 5682, 509 5695, 504 5695, 497 0.0321 0.0234 0.17 0.7689 1.03 0.986 1.08 0.0865 0.0666 0.194 0.7115 1.09 0.957 1.24 0.0772 0.0668 0.248 0.6058 1.08 0.948 1.23 0.0645 0.0671 0.336 0.4737 1.07 0.935 1.22 PRS_PLINK_1.99526231496888e.06 521.1 Dental caries Both 1980 22849 10 digestive chartreuse4 22849, 1980 5707, 466 5706, 510 5721, 511 5703, 493 0.0304 0.0235 0.196 0.7087 1.03 0.985 1.08 0.0891 0.0667 0.181 0.7414 1.09 0.959 1.25 0.0922 0.0667 0.166 0.7787 1.1 0.962 1.25 0.0608 0.0673 0.366 0.4361 1.06 0.931 1.21 PRS_PLINK_1.99526231496888e.06 522 Diseases of pulp and periapical tissues Both 1276 13546 10 digestive chartreuse4 13546, 1276 3399, 310 3390, 300 3375, 348 3380, 318 0.0251 0.029 0.386 0.4132 1.03 0.969 1.09 -0.0292 0.0844 0.729 0.1373 0.971 0.823 1.15 0.129 0.0817 0.115 0.9406 1.14 0.969 1.34 0.0338 0.0834 0.685 0.1641 1.03 0.878 1.22 PRS_PLINK_1.99526231496888e.06 522.5 Periapical abscess Both 834 8939 10 digestive chartreuse4 8939, 834 2248, 211 2229, 193 2262, 223 2199, 207 0.0409 0.0358 0.253 0.5967 1.04 0.971 1.12 -0.0809 0.104 0.435 0.361 0.922 0.753 1.13 0.058 0.1 0.563 0.2493 1.06 0.871 1.29 0.011 0.102 0.915 0.03881 1.01 0.828 1.24 PRS_PLINK_1.99526231496888e.06 523 Gingival and periodontal diseases Both 1208 12891 10 digestive chartreuse4 12891, 1208 3258, 296 3196, 278 3269, 321 3164, 312 0.0408 0.0298 0.17 0.7684 1.04 0.983 1.1 -0.0428 0.087 0.623 0.2058 0.958 0.808 1.14 0.0773 0.0842 0.359 0.4452 1.08 0.916 1.27 0.0858 0.0849 0.312 0.5057 1.09 0.923 1.29 PRS_PLINK_1.99526231496888e.06 523.1 Gingivitis Both 73 795 10 digestive chartreuse4 795, 73 205, 19 194, 18 197, 14 199, 22 0.0499 0.114 0.66 0.1802 1.05 0.841 1.31 -0.0245 0.333 0.941 0.02623 0.976 0.508 1.88 -0.275 0.351 0.433 0.3631 0.76 0.382 1.51 0.159 0.319 0.617 0.21 1.17 0.628 2.19 PRS_PLINK_1.99526231496888e.06 523.3 Periodontitis (acute or chronic) Both 859 9141 10 digestive chartreuse4 9141, 859 2285, 202 2284, 200 2307, 230 2262, 226 0.0511 0.0352 0.147 0.8327 1.05 0.982 1.13 -0.0102 0.104 0.922 0.0355 0.99 0.808 1.21 0.117 0.101 0.246 0.6096 1.12 0.923 1.37 0.125 0.101 0.217 0.6632 1.13 0.929 1.38 PRS_PLINK_1.99526231496888e.06 523.31 Acute periodontitis Both 499 5333 10 digestive chartreuse4 5333, 499 1332, 125 1333, 114 1334, 133 1332, 126 0.0273 0.0468 0.559 0.2527 1.03 0.938 1.13 -0.0952 0.134 0.479 0.3196 0.909 0.699 1.18 0.0582 0.13 0.654 0.1846 1.06 0.822 1.37 0.0107 0.131 0.935 0.02904 1.01 0.781 1.31 PRS_PLINK_1.99526231496888e.06 523.32 Chronic periodontitis Both 405 4296 10 digestive chartreuse4 4296, 405 1093, 97 1063, 87 1068, 111 1071, 110 0.0711 0.0506 0.16 0.7951 1.07 0.972 1.19 -0.0797 0.153 0.602 0.2205 0.923 0.685 1.25 0.164 0.145 0.258 0.5882 1.18 0.887 1.56 0.146 0.145 0.316 0.5005 1.16 0.87 1.54 PRS_PLINK_1.99526231496888e.06 524 Dentofacial anomalies, including malocclusion Both 250 2629 10 digestive chartreuse4 2629, 250 660, 60 652, 59 659, 58 655, 73 0.0999 0.065 0.125 0.9047 1.11 0.973 1.26 -0.00221 0.191 0.991 0.004028 0.998 0.687 1.45 -0.0166 0.191 0.931 0.03121 0.983 0.676 1.43 0.193 0.182 0.291 0.5367 1.21 0.848 1.73 PRS_PLINK_1.99526231496888e.06 524.3 Anomalies of tooth position/malocclusion Both 230 2442 10 digestive chartreuse4 2442, 230 613, 51 606, 57 609, 53 611, 69 0.103 0.0681 0.131 0.8837 1.11 0.97 1.27 0.114 0.2 0.568 0.2456 1.12 0.757 1.66 0.0603 0.203 0.766 0.1157 1.06 0.714 1.58 0.294 0.192 0.127 0.8957 1.34 0.92 1.96 PRS_PLINK_1.99526231496888e.06 525 Other diseases of the teeth and supporting structures Both 1776 19685 10 digestive chartreuse4 19685, 1776 4931, 448 4926, 454 4936, 443 4889, 431 -0.0196 0.0249 0.432 0.3643 0.981 0.934 1.03 0.017 0.0695 0.807 0.09331 1.02 0.888 1.17 -0.0112 0.0699 0.873 0.05907 0.989 0.862 1.13 -0.0277 0.0704 0.694 0.1587 0.973 0.847 1.12 PRS_PLINK_1.99526231496888e.06 525.2 Atrophy of edentulous alveolar ridge Both 55 521 10 digestive chartreuse4 521, 55 134, 13 127, 7 131, 17 129, 18 0.236 0.13 0.0687 1.163 1.27 0.982 1.63 -0.461 0.453 0.308 0.5108 0.631 0.26 1.53 0.314 0.374 0.401 0.3964 1.37 0.657 2.85 0.381 0.374 0.309 0.5099 1.46 0.703 3.05 PRS_PLINK_1.99526231496888e.06 526 Diseases of the jaws Both 657 7001 10 digestive chartreuse4 7001, 657 1769, 159 1734, 164 1771, 167 1727, 167 0.0109 0.0407 0.789 0.1027 1.01 0.933 1.09 0.0471 0.116 0.684 0.1647 1.05 0.835 1.32 0.0463 0.115 0.689 0.162 1.05 0.835 1.31 0.0781 0.115 0.499 0.302 1.08 0.862 1.36 PRS_PLINK_1.99526231496888e.06 526.1 Cysts of the jaws Both 234 2404 10 digestive chartreuse4 2404, 234 608, 65 598, 61 600, 48 597, 60 -0.082 0.0689 0.234 0.6313 0.921 0.805 1.05 -0.031 0.186 0.868 0.06156 0.97 0.673 1.4 -0.295 0.197 0.135 0.8694 0.745 0.506 1.1 -0.063 0.187 0.736 0.1333 0.939 0.651 1.35 PRS_PLINK_1.99526231496888e.06 526.3 Anomalies of jaw size/symmetry Both 49 473 10 digestive chartreuse4 473, 49 119, 9 119, 12 117, 14 118, 14 0.0919 0.138 0.504 0.2975 1.1 0.837 1.44 0.327 0.44 0.456 0.3407 1.39 0.586 3.28 0.509 0.427 0.233 0.6323 1.66 0.72 3.84 0.428 0.432 0.322 0.4923 1.53 0.658 3.58 PRS_PLINK_1.99526231496888e.06 526.4 Temporomandibular joint disorders Both 168 1904 10 digestive chartreuse4 1904, 168 478, 32 474, 50 478, 42 474, 44 0.082 0.0786 0.297 0.5272 1.09 0.93 1.27 0.464 0.232 0.0458 1.339 1.59 1.01 2.51 0.257 0.241 0.287 0.5423 1.29 0.806 2.07 0.348 0.238 0.143 0.8437 1.42 0.889 2.26 PRS_PLINK_1.99526231496888e.06 526.41 Temporomandibular joint disorder, unspecified Both 164 1846 10 digestive chartreuse4 1846, 164 462, 31 470, 49 452, 40 462, 44 0.096 0.0796 0.228 0.6425 1.1 0.942 1.29 0.452 0.235 0.0548 1.261 1.57 0.991 2.49 0.251 0.245 0.305 0.5154 1.29 0.795 2.08 0.372 0.24 0.121 0.9165 1.45 0.906 2.32 PRS_PLINK_1.99526231496888e.06 526.5 Inflammatory conditions of jaw Both 75 816 10 digestive chartreuse4 816, 75 204, 20 204, 16 204, 22 204, 17 0.0631 0.123 0.609 0.2154 1.07 0.836 1.36 -0.245 0.339 0.471 0.3267 0.783 0.403 1.52 0.0948 0.318 0.765 0.1161 1.1 0.59 2.05 -0.149 0.334 0.655 0.1835 0.862 0.448 1.66 PRS_PLINK_1.99526231496888e.06 526.9 Jaw disease NOS Both 158 1726 10 digestive chartreuse4 1726, 158 439, 38 428, 40 429, 40 430, 40 -0.0277 0.0861 0.748 0.1263 0.973 0.822 1.15 0.0627 0.235 0.789 0.1028 1.06 0.672 1.69 0.0702 0.234 0.764 0.1169 1.07 0.678 1.7 0.0889 0.233 0.703 0.1532 1.09 0.692 1.73 PRS_PLINK_1.99526231496888e.06 527 Diseases of the salivary glands Both 455 5107 10 digestive chartreuse4 5107, 455 1279, 112 1284, 114 1268, 108 1275, 121 0.0427 0.0491 0.384 0.4158 1.04 0.948 1.15 0.0169 0.138 0.902 0.04465 1.02 0.776 1.33 -0.0198 0.14 0.887 0.05192 0.98 0.745 1.29 0.0866 0.137 0.526 0.279 1.09 0.834 1.43 PRS_PLINK_1.99526231496888e.06 527.1 Hypertrophy of salivary gland Both 54 601 10 digestive chartreuse4 601, 54 153, 14 150, 13 148, 10 150, 17 0.185 0.137 0.177 0.7527 1.2 0.92 1.57 -0.0584 0.386 0.88 0.05564 0.943 0.442 2.01 -0.38 0.412 0.356 0.4482 0.684 0.305 1.53 0.223 0.367 0.544 0.2648 1.25 0.609 2.57 PRS_PLINK_1.99526231496888e.06 527.2 Sialoadenitis Both 240 2739 10 digestive chartreuse4 2739, 240 703, 70 667, 55 695, 52 673, 63 0.0151 0.0678 0.823 0.08435 1.02 0.889 1.16 -0.195 0.186 0.295 0.5297 0.823 0.572 1.19 -0.286 0.189 0.13 0.8853 0.751 0.519 1.09 -0.05 0.181 0.782 0.1065 0.951 0.667 1.36 PRS_PLINK_1.99526231496888e.06 527.7 Disturbance of salivary secretion Both 42 460 10 digestive chartreuse4 460, 42 115, 10 115, 16 115, 5 115, 11 -0.0542 0.164 0.742 0.1298 0.947 0.686 1.31 0.512 0.415 0.217 0.6637 1.67 0.74 3.76 -0.633 0.528 0.23 0.6378 0.531 0.189 1.49 0.154 0.438 0.726 0.1391 1.17 0.494 2.75 PRS_PLINK_1.99526231496888e.06 527.8 Other specified diseases of the salivary glands Both 84 875 10 digestive chartreuse4 875, 84 219, 19 220, 24 218, 24 218, 17 -0.0491 0.114 0.667 0.176 0.952 0.761 1.19 0.254 0.313 0.418 0.3785 1.29 0.697 2.38 0.227 0.312 0.468 0.3301 1.25 0.68 2.31 -0.118 0.335 0.726 0.1392 0.889 0.461 1.72 PRS_PLINK_1.99526231496888e.06 528 Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue Both 2634 28527 10 digestive chartreuse4 28527, 2634 7123, 676 7125, 654 7220, 650 7043, 654 -0.0108 0.0204 0.598 0.2236 0.989 0.95 1.03 -0.0327 0.0573 0.568 0.2458 0.968 0.865 1.08 -0.0495 0.0574 0.389 0.4105 0.952 0.85 1.07 -0.0218 0.0574 0.704 0.1522 0.978 0.874 1.09 PRS_PLINK_1.99526231496888e.06 528.1 Stomatitis and mucositis Both 301 3440 10 digestive chartreuse4 3440, 301 860, 78 860, 65 858, 69 860, 89 0.0762 0.0591 0.198 0.7037 1.08 0.961 1.21 -0.193 0.173 0.266 0.5756 0.825 0.587 1.16 -0.125 0.171 0.465 0.3322 0.883 0.632 1.23 0.132 0.161 0.414 0.3832 1.14 0.832 1.57 PRS_PLINK_1.99526231496888e.06 528.11 Stomatitis and mucositis (ulcerative) Both 248 2842 10 digestive chartreuse4 2842, 248 711, 63 710, 56 714, 59 706, 70 0.0531 0.0649 0.414 0.3833 1.05 0.928 1.2 -0.126 0.189 0.504 0.2972 0.881 0.608 1.28 -0.0712 0.187 0.703 0.1529 0.931 0.646 1.34 0.108 0.18 0.549 0.2603 1.11 0.783 1.59 PRS_PLINK_1.99526231496888e.06 528.12 Oral aphthae Both 56 628 10 digestive chartreuse4 628, 56 158, 16 155, 8 157, 11 157, 21 0.181 0.135 0.18 0.7442 1.2 0.92 1.56 -0.605 0.421 0.15 0.8231 0.546 0.239 1.25 -0.288 0.391 0.461 0.3359 0.75 0.349 1.61 0.21 0.342 0.539 0.2683 1.23 0.631 2.41 PRS_PLINK_1.99526231496888e.06 528.3 Cellulitis and abscess of oral soft tissues Both 114 1341 10 digestive chartreuse4 1341, 114 338, 35 332, 22 341, 34 329, 23 -0.0526 0.0988 0.595 0.2257 0.949 0.782 1.15 -0.433 0.277 0.118 0.9298 0.649 0.377 1.12 -0.0355 0.249 0.887 0.05216 0.965 0.592 1.57 -0.379 0.273 0.165 0.7822 0.684 0.401 1.17 PRS_PLINK_1.99526231496888e.06 528.4 Cysts of oral soft tissues Both 90 909 10 digestive chartreuse4 909, 90 238, 24 217, 27 228, 23 226, 16 -0.126 0.113 0.265 0.5764 0.881 0.706 1.1 0.177 0.29 0.542 0.2664 1.19 0.676 2.11 -0.00977 0.3 0.974 0.01142 0.99 0.55 1.78 -0.408 0.329 0.215 0.6672 0.665 0.349 1.27 PRS_PLINK_1.99526231496888e.06 528.41 Cyst of the salivary gland Both 65 703 10 digestive chartreuse4 703, 65 178, 20 174, 16 179, 17 172, 12 -0.154 0.134 0.25 0.6015 0.857 0.66 1.11 -0.163 0.34 0.631 0.2001 0.849 0.436 1.65 -0.145 0.337 0.667 0.176 0.865 0.447 1.67 -0.458 0.369 0.215 0.6685 0.633 0.307 1.3 PRS_PLINK_1.99526231496888e.06 528.5 Diseases of lips Both 474 5001 10 digestive chartreuse4 5001, 474 1261, 125 1240, 106 1269, 122 1228, 121 0.0162 0.048 0.736 0.1333 1.02 0.925 1.12 -0.149 0.137 0.278 0.5561 0.862 0.659 1.13 -0.0322 0.133 0.808 0.09257 0.968 0.747 1.26 -0.005 0.133 0.97 0.01321 0.995 0.767 1.29 PRS_PLINK_1.99526231496888e.06 528.6 Leukoplakia of oral mucosa Both 194 2174 10 digestive chartreuse4 2174, 194 544, 62 544, 57 544, 35 542, 40 -0.186 0.0787 0.0177 1.751 0.83 0.711 0.968 -0.089 0.191 0.642 0.1927 0.915 0.629 1.33 -0.551 0.217 0.0111 1.953 0.576 0.376 0.882 -0.424 0.21 0.0431 1.365 0.655 0.434 0.987 PRS_PLINK_1.99526231496888e.06 528.7 Sialolithiasis Both 219 2313 10 digestive chartreuse4 2313, 219 581, 62 581, 52 571, 59 577, 46 -0.087 0.0714 0.223 0.6522 0.917 0.797 1.05 -0.212 0.196 0.279 0.5541 0.809 0.551 1.19 -0.0292 0.189 0.877 0.05681 0.971 0.67 1.41 -0.267 0.201 0.185 0.7339 0.765 0.516 1.14 PRS_PLINK_1.99526231496888e.06 529 Diseases and other conditions of the tongue Both 829 9018 10 digestive chartreuse4 9018, 829 2284, 204 2225, 200 2279, 201 2227, 224 0.0416 0.0358 0.245 0.6104 1.04 0.972 1.12 0.00458 0.104 0.965 0.01559 1 0.82 1.23 -0.0118 0.103 0.909 0.04122 0.988 0.807 1.21 0.119 0.101 0.237 0.6249 1.13 0.924 1.37 PRS_PLINK_1.99526231496888e.06 529.1 Glossitis Both 186 2166 10 digestive chartreuse4 2166, 186 553, 44 535, 38 538, 46 539, 58 0.165 0.0735 0.0252 1.599 1.18 1.02 1.36 -0.118 0.226 0.602 0.2203 0.889 0.571 1.38 0.0667 0.216 0.758 0.1205 1.07 0.7 1.63 0.285 0.206 0.166 0.7797 1.33 0.888 1.99 PRS_PLINK_1.99526231496888e.06 530 Diseases of esophagus Both 21728 206908 10 digestive chartreuse4 206908, 21728 51676, 5264 51767, 5310 52431, 5549 50967, 5598 0.024 0.00708 0.000704 3.153 1.02 1.01 1.04 0.00396 0.0204 0.846 0.07253 1 0.965 1.05 0.0303 0.0202 0.134 0.8722 1.03 0.991 1.07 0.0614 0.0202 0.00243 2.615 1.06 1.02 1.11 PRS_PLINK_1.99526231496888e.06 530.1 Esophagitis, GERD and related diseases Both 20403 201209 10 digestive chartreuse4 201209, 20403 50237, 4915 50699, 5011 50571, 5202 49635, 5268 0.0283 0.00728 1e-04 3.999 1.03 1.01 1.04 0.00769 0.021 0.715 0.1459 1.01 0.967 1.05 0.0435 0.0209 0.037 1.431 1.04 1 1.09 0.0705 0.0209 0.000722 3.142 1.07 1.03 1.12 PRS_PLINK_1.99526231496888e.06 530.11 GERD Both 14956 164974 10 digestive chartreuse4 164974, 14956 41562, 3697 40926, 3625 41526, 3751 40909, 3879 0.027 0.00847 0.00144 2.84 1.03 1.01 1.04 -0.0044 0.0244 0.857 0.06709 0.996 0.949 1.04 0.0154 0.0242 0.525 0.2798 1.02 0.968 1.06 0.0646 0.024 0.00722 2.141 1.07 1.02 1.12 PRS_PLINK_1.99526231496888e.06 530.12 Ulcer of esophagus Both 3155 35906 10 digestive chartreuse4 35906, 3155 8977, 761 8998, 759 8960, 803 8957, 832 0.0524 0.0183 0.00422 2.375 1.05 1.02 1.09 -0.0043 0.0534 0.936 0.02883 0.996 0.897 1.11 0.0565 0.0527 0.284 0.5466 1.06 0.954 1.17 0.0966 0.0524 0.0652 1.186 1.1 0.994 1.22 PRS_PLINK_1.99526231496888e.06 530.14 Reflux esophagitis Both 6827 75648 10 digestive chartreuse4 75648, 6827 18959, 1665 18979, 1653 18792, 1708 18897, 1800 0.035 0.0125 0.00506 2.295 1.04 1.01 1.06 -0.00839 0.0362 0.817 0.08789 0.992 0.924 1.06 0.0359 0.0359 0.317 0.4985 1.04 0.966 1.11 0.0817 0.0356 0.0216 1.665 1.09 1.01 1.16 PRS_PLINK_1.99526231496888e.06 530.2 Esophageal bleeding (varices/hemorrhage) Both 943 11936 10 digestive chartreuse4 11936, 943 2983, 238 2982, 231 2993, 242 2975, 232 -0.0104 0.0337 0.759 0.1198 0.99 0.926 1.06 -0.0301 0.0957 0.753 0.123 0.97 0.804 1.17 0.0108 0.0947 0.91 0.04116 1.01 0.84 1.22 -0.0179 0.0956 0.851 0.06989 0.982 0.814 1.18 PRS_PLINK_1.99526231496888e.06 530.3 Stricture and stenosis of esophagus Both 1178 12933 10 digestive chartreuse4 12933, 1178 3237, 279 3226, 307 3233, 293 3230, 298 -0.00175 0.0301 0.954 0.02055 0.998 0.941 1.06 0.0994 0.0862 0.249 0.6041 1.1 0.933 1.31 0.0505 0.0871 0.562 0.2503 1.05 0.887 1.25 0.0626 0.0871 0.472 0.326 1.06 0.898 1.26 PRS_PLINK_1.99526231496888e.06 530.5 Disorders of esophageal motility Both 399 4577 10 digestive chartreuse4 4577, 399 1156, 105 1138, 96 1138, 109 1144, 89 -0.0241 0.0518 0.641 0.1929 0.976 0.882 1.08 -0.0732 0.146 0.617 0.2099 0.929 0.698 1.24 0.047 0.142 0.741 0.1301 1.05 0.793 1.39 -0.129 0.149 0.389 0.4102 0.879 0.656 1.18 PRS_PLINK_1.99526231496888e.06 530.6 Diverticulum of esophagus, acquired Both 101 1024 10 digestive chartreuse4 1024, 101 257, 29 254, 21 259, 31 253, 20 0.0213 0.0984 0.829 0.08152 1.02 0.842 1.24 -0.331 0.295 0.261 0.583 0.718 0.403 1.28 0.0612 0.27 0.821 0.08591 1.06 0.626 1.8 -0.391 0.302 0.196 0.7081 0.677 0.374 1.22 PRS_PLINK_1.99526231496888e.06 530.7 Gastroesophageal laceration-hemorrhage syndrome Both 215 2522 10 digestive chartreuse4 2522, 215 638, 51 625, 46 628, 76 631, 42 -0.0457 0.0724 0.528 0.2776 0.955 0.829 1.1 -0.0744 0.208 0.721 0.1422 0.928 0.618 1.4 0.44 0.188 0.0196 1.707 1.55 1.07 2.25 -0.13 0.213 0.54 0.2673 0.878 0.578 1.33 PRS_PLINK_1.99526231496888e.06 530.9 Heartburn Both 1495 15580 10 digestive chartreuse4 15580, 1495 3925, 373 3881, 391 3925, 384 3845, 347 -0.0124 0.0274 0.65 0.1869 0.988 0.936 1.04 0.0589 0.0757 0.437 0.3594 1.06 0.914 1.23 0.0292 0.076 0.701 0.1542 1.03 0.887 1.2 -0.0583 0.078 0.455 0.3424 0.943 0.81 1.1 PRS_PLINK_1.99526231496888e.06 531 Peptic ulcer (excl. esophageal) Both 4226 49668 10 digestive chartreuse4 49668, 4226 12445, 1032 12439, 1068 12379, 1025 12387, 1100 0.0181 0.0158 0.252 0.598 1.02 0.987 1.05 0.0348 0.0454 0.444 0.3524 1.04 0.947 1.13 -0.000139 0.0459 0.998 0.001051 1 0.914 1.09 0.072 0.0452 0.111 0.9546 1.07 0.984 1.17 PRS_PLINK_1.99526231496888e.06 531.1 Hemorrhage from gastrointestinal ulcer Both 352 4319 10 digestive chartreuse4 4319, 352 1083, 81 1077, 81 1079, 90 1080, 100 0.092 0.054 0.0881 1.055 1.1 0.986 1.22 0.00768 0.162 0.962 0.01675 1.01 0.734 1.38 0.106 0.158 0.501 0.2999 1.11 0.816 1.51 0.203 0.155 0.19 0.7205 1.22 0.904 1.66 PRS_PLINK_1.99526231496888e.06 531.2 Gastric ulcer Both 2423 28820 10 digestive chartreuse4 28820, 2423 7211, 608 7245, 622 7192, 576 7161, 616 0.00441 0.021 0.834 0.079 1 0.964 1.05 0.0175 0.0594 0.768 0.1149 1.02 0.906 1.14 -0.0505 0.0604 0.403 0.3945 0.951 0.845 1.07 0.0241 0.0596 0.686 0.1639 1.02 0.912 1.15 PRS_PLINK_1.99526231496888e.06 531.3 Duodenal ulcer Both 1799 20881 10 digestive chartreuse4 20881, 1799 5232, 427 5203, 454 5220, 431 5220, 486 0.0211 0.0243 0.386 0.413 1.02 0.974 1.07 0.066 0.0701 0.346 0.4603 1.07 0.931 1.23 0.0132 0.0709 0.853 0.06923 1.01 0.882 1.16 0.137 0.0691 0.0474 1.324 1.15 1 1.31 PRS_PLINK_1.99526231496888e.06 531.4 Peptic ulcer, site unspecified Both 239 2939 10 digestive chartreuse4 2939, 239 734, 61 735, 63 734, 62 735, 53 -0.0154 0.0667 0.817 0.08752 0.985 0.864 1.12 0.0397 0.185 0.831 0.08066 1.04 0.724 1.5 0.0187 0.186 0.92 0.03627 1.02 0.708 1.47 -0.128 0.193 0.506 0.2955 0.88 0.603 1.28 PRS_PLINK_1.99526231496888e.06 532 Dysphagia Both 4228 46637 10 digestive chartreuse4 46637, 4228 11676, 1050 11660, 1058 11666, 1064 11619, 1054 0.0137 0.0159 0.39 0.409 1.01 0.983 1.05 0.01 0.0455 0.826 0.08318 1.01 0.924 1.1 0.0145 0.0454 0.75 0.125 1.01 0.928 1.11 0.0131 0.0456 0.774 0.1112 1.01 0.927 1.11 PRS_PLINK_1.99526231496888e.06 535 Gastritis and duodenitis Both 18173 191285 10 digestive chartreuse4 191285, 18173 47888, 4503 47775, 4452 48088, 4591 47471, 4622 0.00879 0.00773 0.256 0.5925 1.01 0.994 1.02 -0.0108 0.0221 0.627 0.203 0.989 0.947 1.03 0.0123 0.022 0.574 0.2409 1.01 0.97 1.06 0.0304 0.022 0.166 0.7799 1.03 0.987 1.08 PRS_PLINK_1.99526231496888e.06 535.1 Acute gastritis Both 717 8385 10 digestive chartreuse4 8385, 717 2098, 180 2099, 181 2093, 174 2094, 182 0.00753 0.0383 0.844 0.07353 1.01 0.935 1.09 -0.00149 0.109 0.989 0.004758 0.999 0.806 1.24 -0.0259 0.11 0.815 0.08906 0.974 0.785 1.21 0.0101 0.109 0.926 0.03334 1.01 0.815 1.25 PRS_PLINK_1.99526231496888e.06 535.2 Atrophic gastritis Both 234 2533 10 digestive chartreuse4 2533, 234 638, 62 628, 60 635, 53 631, 59 -0.00796 0.0673 0.906 0.04296 0.992 0.87 1.13 -0.0208 0.188 0.912 0.04013 0.979 0.678 1.42 -0.13 0.194 0.503 0.298 0.878 0.601 1.28 -0.0381 0.19 0.841 0.07535 0.963 0.664 1.4 PRS_PLINK_1.99526231496888e.06 535.6 Duodenitis Both 4682 54128 10 digestive chartreuse4 54128, 4682 13635, 1190 13409, 1132 13565, 1151 13499, 1207 0.00653 0.0152 0.667 0.1757 1.01 0.977 1.04 -0.0327 0.0432 0.449 0.3476 0.968 0.889 1.05 -0.0256 0.0431 0.553 0.2576 0.975 0.896 1.06 0.0313 0.0427 0.463 0.3345 1.03 0.949 1.12 PRS_PLINK_1.99526231496888e.06 535.8 Other specified gastritis Both 5239 57860 10 digestive chartreuse4 57860, 5239 14487, 1280 14429, 1268 14461, 1363 14465, 1327 0.01 0.0144 0.485 0.3143 1.01 0.982 1.04 -0.00417 0.0413 0.92 0.03643 0.996 0.918 1.08 0.0662 0.0407 0.103 0.9856 1.07 0.987 1.16 0.0425 0.041 0.299 0.5241 1.04 0.963 1.13 PRS_PLINK_1.99526231496888e.06 535.9 Gastritis and duodenitis, NOS Both 83 858 10 digestive chartreuse4 858, 83 214, 22 216, 21 214, 19 213, 21 0.0299 0.114 0.794 0.1004 1.03 0.824 1.29 -0.0475 0.313 0.879 0.05585 0.954 0.516 1.76 -0.103 0.322 0.749 0.1257 0.902 0.48 1.69 -0.0313 0.314 0.921 0.03585 0.969 0.524 1.79 PRS_PLINK_1.99526231496888e.06 536.8 Dyspepsia and other specified disorders of function of stomach Both 175 1868 10 digestive chartreuse4 1868, 175 468, 39 469, 44 464, 44 467, 48 0.0932 0.0766 0.224 0.6505 1.1 0.945 1.28 0.112 0.226 0.621 0.2069 1.12 0.718 1.74 0.109 0.226 0.629 0.2012 1.12 0.716 1.74 0.212 0.222 0.34 0.469 1.24 0.8 1.91 PRS_PLINK_1.99526231496888e.06 537 Other disorders of stomach and duodenum Both 2045 24138 10 digestive chartreuse4 24138, 2045 6074, 520 6008, 444 6075, 550 5975, 530 0.0303 0.0229 0.184 0.7341 1.03 0.986 1.08 -0.147 0.067 0.0288 1.541 0.864 0.757 0.985 0.0577 0.0637 0.365 0.4372 1.06 0.935 1.2 0.0395 0.0644 0.54 0.2678 1.04 0.917 1.18 PRS_PLINK_1.99526231496888e.06 540 Appendiceal conditions Both 2266 23459 10 digestive chartreuse4 23459, 2266 5859, 552 5871, 585 5877, 581 5846, 547 0.000387 0.0218 0.986 0.006211 1 0.959 1.04 0.0561 0.0621 0.366 0.4361 1.06 0.937 1.19 0.0477 0.0622 0.444 0.3531 1.05 0.928 1.18 -0.00241 0.0631 0.97 0.01345 0.998 0.881 1.13 PRS_PLINK_1.99526231496888e.06 540.1 Appendicitis Both 2134 21972 10 digestive chartreuse4 21972, 2134 5493, 526 5531, 554 5461, 539 5481, 514 -0.00164 0.0224 0.942 0.02608 0.998 0.955 1.04 0.0441 0.0637 0.489 0.3108 1.05 0.922 1.18 0.0304 0.0642 0.636 0.1969 1.03 0.909 1.17 -0.016 0.0649 0.805 0.09427 0.984 0.867 1.12 PRS_PLINK_1.99526231496888e.06 540.11 Acute appendicitis Both 1944 19778 10 digestive chartreuse4 19778, 1944 4966, 488 4921, 501 4952, 490 4934, 464 -0.0133 0.0236 0.572 0.2426 0.987 0.942 1.03 0.0333 0.0666 0.618 0.2094 1.03 0.907 1.18 0.00707 0.067 0.916 0.03815 1.01 0.883 1.15 -0.041 0.0679 0.546 0.2626 0.96 0.84 1.1 PRS_PLINK_1.99526231496888e.06 550 Abdominal hernia Both 29510 211276 10 digestive chartreuse4 211276, 29510 52877, 7306 52819, 7128 53555, 7479 51961, 7584 0.0123 0.00623 0.0484 1.315 1.01 1 1.02 -0.0322 0.0179 0.0721 1.142 0.968 0.935 1 -0.0111 0.0177 0.53 0.2755 0.989 0.955 1.02 0.0118 0.0177 0.504 0.2972 1.01 0.977 1.05 PRS_PLINK_1.99526231496888e.06 550.1 Inguinal hernia Both 10584 84628 10 digestive chartreuse4 84628, 10584 21483, 2795 20825, 2504 21188, 2621 21104, 2659 -0.00821 0.0102 0.422 0.3744 0.992 0.972 1.01 -0.0821 0.0293 0.00504 2.297 0.921 0.87 0.976 -0.0638 0.0289 0.0275 1.561 0.938 0.886 0.993 -0.0532 0.0289 0.0653 1.185 0.948 0.896 1 PRS_PLINK_1.99526231496888e.06 550.2 Diaphragmatic hernia Both 16946 174899 10 digestive chartreuse4 174899, 16946 43786, 4150 43810, 4113 43890, 4288 43360, 4388 0.0252 0.00797 0.00156 2.806 1.03 1.01 1.04 -0.0122 0.023 0.598 0.2236 0.988 0.944 1.03 0.0242 0.0228 0.289 0.5394 1.02 0.98 1.07 0.055 0.0227 0.0155 1.809 1.06 1.01 1.1 PRS_PLINK_1.99526231496888e.06 550.3 Femoral hernia Both 492 4835 10 digestive chartreuse4 4835, 492 1239, 138 1180, 123 1212, 119 1203, 112 -0.0595 0.0473 0.208 0.6811 0.942 0.859 1.03 -0.069 0.13 0.596 0.2248 0.933 0.723 1.2 -0.124 0.131 0.343 0.4652 0.883 0.684 1.14 -0.175 0.133 0.188 0.7269 0.839 0.647 1.09 PRS_PLINK_1.99526231496888e.06 550.4 Umbilical hernia Both 2206 26237 10 digestive chartreuse4 26237, 2206 6575, 491 6534, 530 6591, 579 6525, 606 0.0822 0.0216 0.000138 3.86 1.09 1.04 1.13 0.0836 0.065 0.198 0.7033 1.09 0.957 1.23 0.163 0.0637 0.0106 1.976 1.18 1.04 1.33 0.219 0.0632 0.000537 3.27 1.24 1.1 1.41 PRS_PLINK_1.99526231496888e.06 550.5 Ventral hernia Both 2061 24752 10 digestive chartreuse4 24752, 2061 6196, 512 6240, 511 6171, 535 6140, 502 0.00717 0.0229 0.754 0.1224 1.01 0.963 1.05 -0.00669 0.065 0.918 0.03713 0.993 0.875 1.13 0.0492 0.0643 0.445 0.3521 1.05 0.926 1.19 -0.00737 0.0653 0.91 0.04088 0.993 0.873 1.13 PRS_PLINK_1.99526231496888e.06 555 Inflammatory bowel disease and other gastroenteritis and colitis Both 2931 33097 10 digestive chartreuse4 33097, 2931 8269, 751 8271, 692 8316, 733 8227, 753 0.0136 0.0192 0.478 0.3204 1.01 0.976 1.05 -0.0812 0.0549 0.139 0.8561 0.922 0.828 1.03 -0.0277 0.0542 0.609 0.2151 0.973 0.875 1.08 0.0125 0.0539 0.816 0.0882 1.01 0.911 1.13 PRS_PLINK_1.99526231496888e.06 555.1 Regional enteritis Both 1107 13156 10 digestive chartreuse4 13156, 1107 3289, 282 3281, 267 3299, 277 3278, 280 0.0138 0.0311 0.658 0.1819 1.01 0.954 1.08 -0.0557 0.0887 0.53 0.2758 0.946 0.795 1.13 -0.0224 0.088 0.799 0.0974 0.978 0.823 1.16 0.0016 0.0879 0.985 0.006358 1 0.843 1.19 PRS_PLINK_1.99526231496888e.06 555.2 Ulcerative colitis Both 2119 23491 10 digestive chartreuse4 23491, 2119 5915, 561 5875, 494 5877, 519 5817, 544 0.00519 0.0226 0.818 0.08719 1.01 0.962 1.05 -0.117 0.0643 0.0687 1.163 0.89 0.784 1.01 -0.0684 0.0636 0.283 0.5489 0.934 0.824 1.06 -0.00867 0.063 0.891 0.05034 0.991 0.876 1.12 PRS_PLINK_1.99526231496888e.06 555.21 Ulcerative colitis (chronic) Both 381 4097 10 digestive chartreuse4 4097, 381 1026, 104 1030, 76 1025, 98 1015, 103 0.0169 0.0529 0.75 0.1251 1.02 0.917 1.13 -0.311 0.156 0.046 1.337 0.732 0.539 0.995 -0.0657 0.147 0.655 0.1838 0.936 0.702 1.25 0.029 0.146 0.842 0.07472 1.03 0.774 1.37 PRS_PLINK_1.99526231496888e.06 556 Ulceration of the lower GI tract Both 693 7778 10 digestive chartreuse4 7778, 693 1943, 157 1966, 154 1948, 193 1919, 189 0.0894 0.0385 0.0203 1.692 1.09 1.01 1.18 -0.0338 0.117 0.773 0.1119 0.967 0.768 1.22 0.205 0.112 0.0662 1.179 1.23 0.986 1.53 0.201 0.112 0.0737 1.133 1.22 0.981 1.52 PRS_PLINK_1.99526231496888e.06 556.1 Ulceration of intestine Both 429 4916 10 digestive chartreuse4 4916, 429 1233, 99 1229, 105 1232, 120 1220, 105 0.037 0.0494 0.454 0.3433 1.04 0.942 1.14 0.0674 0.145 0.641 0.1929 1.07 0.806 1.42 0.194 0.141 0.168 0.774 1.21 0.921 1.6 0.0688 0.145 0.636 0.1967 1.07 0.806 1.42 PRS_PLINK_1.99526231496888e.06 557 Intestinal malabsorption (non-celiac) Both 198 2289 10 digestive chartreuse4 2289, 198 573, 51 572, 47 572, 54 572, 46 -0.0029 0.0754 0.969 0.01353 0.997 0.86 1.16 -0.0773 0.208 0.711 0.1482 0.926 0.615 1.39 0.0667 0.202 0.741 0.13 1.07 0.719 1.59 -0.0375 0.211 0.859 0.066 0.963 0.637 1.46 PRS_PLINK_1.99526231496888e.06 557.1 Celiac disease Both 1289 13848 10 digestive chartreuse4 13848, 1289 3459, 343 3470, 312 3491, 337 3423, 296 -0.0334 0.0295 0.258 0.5885 0.967 0.913 1.02 -0.0989 0.0817 0.226 0.6456 0.906 0.772 1.06 -0.023 0.0803 0.775 0.111 0.977 0.835 1.14 -0.131 0.0829 0.115 0.9403 0.877 0.746 1.03 PRS_PLINK_1.99526231496888e.06 558 Noninfectious gastroenteritis Both 10139 116051 10 digestive chartreuse4 116051, 10139 28967, 2455 29156, 2499 29210, 2635 28671, 2545 0.0277 0.0103 0.00709 2.149 1.03 1.01 1.05 0.0114 0.0296 0.701 0.1542 1.01 0.954 1.07 0.0643 0.0293 0.028 1.552 1.07 1.01 1.13 0.0508 0.0295 0.0856 1.068 1.05 0.993 1.11 PRS_PLINK_1.99526231496888e.06 559 Ileostomy status Both 998 11716 10 digestive chartreuse4 11716, 998 2935, 263 2927, 230 2924, 275 2927, 230 -0.0136 0.033 0.681 0.1668 0.987 0.925 1.05 -0.126 0.0937 0.177 0.7513 0.881 0.733 1.06 0.0556 0.09 0.537 0.2703 1.06 0.886 1.26 -0.126 0.0939 0.179 0.7465 0.881 0.733 1.06 PRS_PLINK_1.99526231496888e.06 560 Intestinal obstruction without mention of hernia Both 2534 28294 10 digestive chartreuse4 28294, 2534 7124, 632 7020, 593 7101, 643 7040, 666 0.0278 0.0206 0.179 0.7475 1.03 0.987 1.07 -0.0488 0.0595 0.413 0.3845 0.952 0.847 1.07 0.0246 0.0584 0.673 0.1719 1.02 0.914 1.15 0.0649 0.0581 0.264 0.5787 1.07 0.952 1.2 PRS_PLINK_1.99526231496888e.06 560.1 Paralytic ileus Both 318 3637 10 digestive chartreuse4 3637, 318 921, 77 902, 76 904, 70 909, 95 0.0421 0.0574 0.463 0.3344 1.04 0.932 1.17 0.0106 0.167 0.949 0.02259 1.01 0.729 1.4 -0.0765 0.17 0.653 0.1852 0.926 0.664 1.29 0.212 0.159 0.184 0.735 1.24 0.904 1.69 PRS_PLINK_1.99526231496888e.06 560.2 Impaction of intestine Both 165 1951 10 digestive chartreuse4 1951, 165 487, 44 488, 38 487, 34 488, 49 0.0983 0.0776 0.205 0.6876 1.1 0.948 1.28 -0.171 0.227 0.453 0.3442 0.843 0.54 1.32 -0.225 0.234 0.336 0.4742 0.798 0.504 1.26 0.106 0.217 0.624 0.205 1.11 0.727 1.7 PRS_PLINK_1.99526231496888e.06 560.3 Peritoneal or intestinal adhesions Both 547 6023 10 digestive chartreuse4 6023, 547 1508, 133 1515, 140 1494, 152 1505, 122 -0.0487 0.0451 0.281 0.5514 0.952 0.872 1.04 0.0329 0.126 0.794 0.1002 1.03 0.807 1.32 0.144 0.124 0.245 0.6106 1.15 0.906 1.47 -0.0752 0.13 0.563 0.2496 0.928 0.719 1.2 PRS_PLINK_1.99526231496888e.06 560.4 Other intestinal obstruction Both 2181 24215 10 digestive chartreuse4 24215, 2181 6092, 556 6008, 505 6078, 564 6029, 556 0.00811 0.0224 0.717 0.1445 1.01 0.965 1.05 -0.0829 0.064 0.195 0.7093 0.92 0.812 1.04 0.02 0.0624 0.749 0.1256 1.02 0.903 1.15 0.0132 0.0627 0.833 0.07914 1.01 0.896 1.15 PRS_PLINK_1.99526231496888e.06 561 Symptoms involving digestive system Both 11071 118093 10 digestive chartreuse4 118093, 11071 29518, 2789 29531, 2752 29994, 2837 29016, 2691 0.00011 0.00994 0.991 0.00384 1 0.981 1.02 -0.0141 0.0281 0.617 0.21 0.986 0.933 1.04 0.00087 0.0279 0.975 0.01094 1 0.948 1.06 -0.0187 0.0283 0.509 0.2935 0.981 0.929 1.04 PRS_PLINK_1.99526231496888e.06 561.1 Diarrhea Both 307 3348 10 digestive chartreuse4 3348, 307 853, 85 826, 62 843, 89 825, 71 -0.0491 0.0604 0.416 0.381 0.952 0.846 1.07 -0.272 0.173 0.116 0.9373 0.762 0.543 1.07 0.0603 0.158 0.703 0.153 1.06 0.779 1.45 -0.147 0.167 0.378 0.4225 0.863 0.622 1.2 PRS_PLINK_1.99526231496888e.06 561.2 Flatulence Both 1188 12682 10 digestive chartreuse4 12682, 1188 3186, 298 3188, 296 3139, 285 3166, 309 0.0142 0.0302 0.637 0.1958 1.01 0.956 1.08 -0.00715 0.0856 0.933 0.0299 0.993 0.84 1.17 -0.0283 0.0864 0.744 0.1287 0.972 0.821 1.15 0.0434 0.085 0.61 0.2149 1.04 0.884 1.23 PRS_PLINK_1.99526231496888e.06 562 Diverticulosis and diverticulitis Both 17018 154122 10 digestive chartreuse4 154122, 17018 38624, 4161 38423, 4187 38739, 4318 38290, 4347 0.0136 0.00804 0.0903 1.044 1.01 0.998 1.03 0.00605 0.0231 0.793 0.1005 1.01 0.962 1.05 0.0217 0.0229 0.345 0.4616 1.02 0.977 1.07 0.0297 0.0229 0.195 0.7091 1.03 0.985 1.08 PRS_PLINK_1.99526231496888e.06 562.1 Diverticulosis Both 16988 154070 10 digestive chartreuse4 154070, 16988 38607, 4153 38415, 4184 38716, 4311 38286, 4335 0.0132 0.00804 0.102 0.9934 1.01 0.997 1.03 0.00707 0.0231 0.759 0.1195 1.01 0.963 1.05 0.0222 0.023 0.334 0.4758 1.02 0.977 1.07 0.0288 0.023 0.21 0.6779 1.03 0.984 1.08 PRS_PLINK_1.99526231496888e.06 563 Constipation Both 6720 75745 10 digestive chartreuse4 75745, 6720 18952, 1690 18902, 1636 18964, 1699 18903, 1694 0.0104 0.0127 0.412 0.3855 1.01 0.986 1.04 -0.0296 0.0362 0.413 0.3838 0.971 0.904 1.04 0.0075 0.0359 0.834 0.07862 1.01 0.939 1.08 0.0111 0.0359 0.757 0.121 1.01 0.942 1.08 PRS_PLINK_1.99526231496888e.06 564 Functional digestive disorders Both 14222 154657 10 digestive chartreuse4 154657, 14222 38819, 3507 38600, 3470 38806, 3634 38391, 3606 0.015 0.00872 0.086 1.065 1.02 0.998 1.03 -0.00554 0.025 0.825 0.08381 0.994 0.947 1.04 0.0352 0.0247 0.154 0.8114 1.04 0.987 1.09 0.039 0.0248 0.116 0.9359 1.04 0.99 1.09 PRS_PLINK_1.99526231496888e.06 564.1 Irritable Bowel Syndrome Both 4007 42741 10 digestive chartreuse4 42741, 4007 10694, 977 10672, 959 10886, 1048 10483, 1022 0.0294 0.0165 0.0742 1.13 1.03 0.997 1.06 -0.0172 0.0474 0.718 0.1441 0.983 0.896 1.08 0.0526 0.0465 0.258 0.5886 1.05 0.962 1.15 0.0681 0.0468 0.146 0.8358 1.07 0.977 1.17 PRS_PLINK_1.99526231496888e.06 564.8 Abnormal findings on exam of gastrointestinal tract/ abdominal area Both 1036 11923 10 digestive chartreuse4 11923, 1036 2978, 233 3010, 280 2951, 251 2981, 271 0.028 0.0326 0.39 0.4091 1.03 0.965 1.1 0.171 0.0922 0.0635 1.197 1.19 0.99 1.42 0.0832 0.0943 0.378 0.4228 1.09 0.903 1.31 0.159 0.0929 0.0876 1.058 1.17 0.977 1.41 PRS_PLINK_1.99526231496888e.06 564.9 Personal history of diseases of digestive system Both 9638 108537 10 digestive chartreuse4 108537, 9638 27330, 2413 27101, 2350 26938, 2436 27134, 2434 0.00837 0.0106 0.427 0.3692 1.01 0.988 1.03 -0.0183 0.0302 0.544 0.2642 0.982 0.925 1.04 0.0253 0.03 0.399 0.3989 1.03 0.967 1.09 0.0187 0.03 0.534 0.2721 1.02 0.961 1.08 PRS_PLINK_1.99526231496888e.06 565 Anal and rectal conditions Both 10014 106323 10 digestive chartreuse4 106323, 10014 26668, 2557 26740, 2478 26369, 2466 26511, 2508 -0.0081 0.0105 0.438 0.358 0.992 0.972 1.01 -0.0343 0.0295 0.245 0.6108 0.966 0.912 1.02 -0.0242 0.0295 0.412 0.3851 0.976 0.921 1.03 -0.0114 0.0294 0.7 0.1552 0.989 0.933 1.05 PRS_PLINK_1.99526231496888e.06 565.1 Anal and rectal polyp Both 4897 51529 10 digestive chartreuse4 51529, 4897 12874, 1260 12875, 1181 12890, 1218 12869, 1233 -0.00891 0.0149 0.551 0.2591 0.991 0.963 1.02 -0.0648 0.0424 0.126 0.8992 0.937 0.863 1.02 -0.0346 0.0421 0.411 0.3866 0.966 0.89 1.05 -0.0205 0.042 0.626 0.2036 0.98 0.902 1.06 PRS_PLINK_1.99526231496888e.06 567 Peritonitis and retroperitoneal infections Both 519 6610 10 digestive chartreuse4 6610, 519 1657, 131 1653, 110 1647, 147 1650, 131 0.0452 0.0446 0.311 0.507 1.05 0.959 1.14 -0.167 0.133 0.209 0.6799 0.846 0.652 1.1 0.128 0.124 0.305 0.5157 1.14 0.89 1.45 0.0117 0.128 0.927 0.03293 1.01 0.787 1.3 PRS_PLINK_1.99526231496888e.06 568 Other disorders of peritoneum Both 2143 24137 10 digestive chartreuse4 24137, 2143 6036, 518 6030, 497 6128, 573 5938, 554 0.0575 0.0222 0.00953 2.021 1.06 1.01 1.11 -0.0373 0.0653 0.568 0.2454 0.963 0.848 1.09 0.0866 0.0633 0.171 0.7674 1.09 0.963 1.23 0.0896 0.0638 0.161 0.7944 1.09 0.965 1.24 PRS_PLINK_1.99526231496888e.06 568.1 Peritoneal adhesions (postoperative) (postinfection) Both 2045 22970 10 digestive chartreuse4 22970, 2045 5738, 499 5753, 475 5824, 534 5650, 536 0.0582 0.0227 0.0102 1.99 1.06 1.01 1.11 -0.0491 0.0667 0.461 0.3359 0.952 0.835 1.08 0.0536 0.065 0.41 0.3875 1.06 0.929 1.2 0.0931 0.065 0.152 0.8178 1.1 0.966 1.25 PRS_PLINK_1.99526231496888e.06 569 Other disorders of intestine Both 2686 29901 10 digestive chartreuse4 29901, 2686 7466, 656 7540, 638 7453, 693 7429, 699 0.031 0.0199 0.119 0.9249 1.03 0.992 1.07 -0.0386 0.0579 0.505 0.297 0.962 0.859 1.08 0.0575 0.0568 0.312 0.5059 1.06 0.947 1.18 0.0716 0.0568 0.207 0.6832 1.07 0.961 1.2 PRS_PLINK_1.99526231496888e.06 569.1 Toxic gastroenteritis and colitis Both 94 1003 10 digestive chartreuse4 1003, 94 253, 24 254, 29 245, 17 250, 24 0.0121 0.107 0.91 0.04086 1.01 0.82 1.25 0.149 0.284 0.599 0.2223 1.16 0.665 2.03 -0.303 0.319 0.343 0.4651 0.739 0.395 1.38 0.0461 0.297 0.877 0.05711 1.05 0.585 1.88 PRS_PLINK_1.99526231496888e.06 569.2 Gastrointestinal complications Both 318 3425 10 digestive chartreuse4 3425, 318 859, 81 853, 66 865, 84 847, 87 0.0714 0.0571 0.211 0.6759 1.07 0.96 1.2 -0.187 0.171 0.276 0.5592 0.83 0.593 1.16 0.0188 0.162 0.908 0.0421 1.02 0.742 1.4 0.0801 0.161 0.619 0.2083 1.08 0.79 1.49 PRS_PLINK_1.99526231496888e.06 571 Chronic liver disease and cirrhosis Both 1504 21458 10 digestive chartreuse4 21458, 1504 5377, 353 5387, 352 5360, 383 5331, 416 0.067 0.0261 0.0104 1.984 1.07 1.02 1.13 -0.00407 0.0776 0.958 0.01855 0.996 0.855 1.16 0.0887 0.0761 0.244 0.6126 1.09 0.941 1.27 0.176 0.0749 0.0184 1.736 1.19 1.03 1.38 PRS_PLINK_1.99526231496888e.06 571.5 Other chronic nonalcoholic liver disease Both 944 12403 10 digestive chartreuse4 12403, 944 3120, 221 3103, 224 3119, 241 3058, 258 0.06 0.0331 0.0701 1.154 1.06 0.995 1.13 0.0179 0.0978 0.855 0.06822 1.02 0.84 1.23 0.0893 0.0963 0.354 0.4513 1.09 0.905 1.32 0.175 0.095 0.065 1.187 1.19 0.989 1.44 PRS_PLINK_1.99526231496888e.06 571.51 Cirrhosis of liver without mention of alcohol Both 55 810 10 digestive chartreuse4 810, 55 205, 15 200, 13 202, 13 203, 14 0.0131 0.134 0.922 0.03519 1.01 0.779 1.32 -0.135 0.373 0.717 0.1445 0.873 0.42 1.82 -0.0631 0.374 0.866 0.06251 0.939 0.451 1.95 0.0173 0.379 0.963 0.01615 1.02 0.484 2.14 PRS_PLINK_1.99526231496888e.06 571.6 Primary biliary cirrhosis Both 105 1910 10 digestive chartreuse4 1910, 105 485, 24 477, 21 471, 26 477, 34 0.133 0.0945 0.161 0.7938 1.14 0.949 1.37 -0.0586 0.297 0.844 0.07382 0.943 0.527 1.69 0.126 0.282 0.654 0.1845 1.13 0.653 1.97 0.349 0.267 0.191 0.7194 1.42 0.84 2.39 PRS_PLINK_1.99526231496888e.06 571.8 Liver abscess and sequelae of chronic liver disease Both 430 6942 10 digestive chartreuse4 6942, 430 1736, 101 1752, 103 1725, 102 1728, 124 0.0651 0.0486 0.18 0.7449 1.07 0.97 1.17 -0.00144 0.143 0.992 0.003514 0.999 0.754 1.32 0.0201 0.143 0.889 0.05125 1.02 0.77 1.35 0.218 0.137 0.112 0.9513 1.24 0.95 1.63 PRS_PLINK_1.99526231496888e.06 571.81 Portal hypertension Both 214 3717 10 digestive chartreuse4 3717, 214 932, 46 931, 50 923, 45 929, 73 0.129 0.067 0.0551 1.259 1.14 0.997 1.3 0.0751 0.206 0.716 0.1451 1.08 0.719 1.62 -0.0148 0.211 0.944 0.02499 0.985 0.652 1.49 0.478 0.191 0.0125 1.902 1.61 1.11 2.35 PRS_PLINK_1.99526231496888e.06 572 Ascites (non malignant) Both 870 11009 10 digestive chartreuse4 11009, 870 2759, 196 2766, 214 2768, 239 2709, 221 0.087 0.0342 0.011 1.961 1.09 1.02 1.17 0.081 0.102 0.428 0.3689 1.08 0.888 1.32 0.197 0.0998 0.0488 1.311 1.22 1 1.48 0.142 0.102 0.163 0.7876 1.15 0.944 1.41 PRS_PLINK_1.99526231496888e.06 573 Other disorders of liver Both 842 10720 10 digestive chartreuse4 10720, 842 2684, 176 2674, 220 2680, 211 2678, 234 0.0782 0.0349 0.025 1.602 1.08 1.01 1.16 0.22 0.104 0.0352 1.453 1.25 1.02 1.53 0.183 0.105 0.0816 1.088 1.2 0.977 1.48 0.291 0.103 0.00475 2.323 1.34 1.09 1.64 PRS_PLINK_1.99526231496888e.06 573.2 Liver replaced by transplant Both 15 719 10 digestive chartreuse4 719, 15 180, 6 181, 2 178, 3 180, 4 -0.183 0.257 0.477 0.3212 0.833 0.503 1.38 -0.922 0.657 0.16 0.7954 0.398 0.11 1.44 -0.533 0.596 0.371 0.4303 0.587 0.183 1.89 -0.351 0.561 0.531 0.2746 0.704 0.234 2.11 PRS_PLINK_1.99526231496888e.06 573.3 Hepatomegaly Both 145 2103 10 digestive chartreuse4 2103, 145 525, 31 527, 29 529, 48 521, 37 0.0753 0.0818 0.357 0.4473 1.08 0.919 1.27 -0.0558 0.258 0.829 0.08143 0.946 0.57 1.57 0.422 0.234 0.0717 1.144 1.52 0.963 2.41 0.197 0.248 0.425 0.3716 1.22 0.75 1.98 PRS_PLINK_1.99526231496888e.06 573.5 Jaundice (not of newborn) Both 498 6264 10 digestive chartreuse4 6264, 498 1574, 124 1559, 126 1566, 119 1564, 129 0.000884 0.046 0.985 0.006711 1 0.915 1.1 0.0249 0.131 0.849 0.07102 1.03 0.793 1.32 -0.038 0.132 0.774 0.1111 0.963 0.743 1.25 0.0566 0.13 0.664 0.1777 1.06 0.82 1.37 PRS_PLINK_1.99526231496888e.06 573.7 Abnormal results of function study of liver Both 2045 24822 10 digestive chartreuse4 24822, 2045 6217, 503 6209, 479 6206, 528 6184, 534 0.0306 0.0227 0.177 0.752 1.03 0.986 1.08 -0.0477 0.0662 0.472 0.3264 0.953 0.837 1.09 0.0562 0.0648 0.386 0.4137 1.06 0.932 1.2 0.0759 0.0647 0.241 0.6188 1.08 0.95 1.22 PRS_PLINK_1.99526231496888e.06 573.9 Abnormal serum enzyme levels Both 118 1416 10 digestive chartreuse4 1416, 118 355, 31 354, 29 353, 22 354, 36 0.0502 0.0909 0.581 0.2359 1.05 0.88 1.26 -0.0749 0.264 0.776 0.1099 0.928 0.553 1.56 -0.316 0.281 0.261 0.5836 0.729 0.421 1.26 0.197 0.253 0.435 0.3613 1.22 0.742 2 PRS_PLINK_1.99526231496888e.06 574 Cholelithiasis and cholecystitis Both 9995 116039 10 digestive chartreuse4 116039, 9995 29035, 2456 29217, 2489 28748, 2441 29008, 2607 0.0247 0.0104 0.0174 1.761 1.03 1 1.05 0.0088 0.0296 0.767 0.1155 1.01 0.952 1.07 0.0065 0.0298 0.827 0.08243 1.01 0.949 1.07 0.0674 0.0294 0.0218 1.662 1.07 1.01 1.13 PRS_PLINK_1.99526231496888e.06 574.1 Cholelithiasis Both 8674 100916 10 digestive chartreuse4 100916, 8674 25228, 2139 25341, 2171 25103, 2119 25215, 2244 0.0197 0.0112 0.0781 1.108 1.02 0.998 1.04 0.0117 0.0317 0.712 0.1477 1.01 0.951 1.08 -0.00199 0.0319 0.95 0.02211 0.998 0.937 1.06 0.0537 0.0315 0.0887 1.052 1.06 0.992 1.12 PRS_PLINK_1.99526231496888e.06 574.11 Cholelithiasis with acute cholecystitis Both 915 10927 10 digestive chartreuse4 10927, 915 2730, 231 2735, 241 2727, 223 2732, 220 -0.0271 0.0345 0.432 0.3645 0.973 0.91 1.04 0.0419 0.0957 0.662 0.1793 1.04 0.864 1.26 -0.0306 0.0974 0.753 0.1231 0.97 0.801 1.17 -0.0381 0.0978 0.697 0.1566 0.963 0.795 1.17 PRS_PLINK_1.99526231496888e.06 574.12 Cholelithiasis with other cholecystitis Both 3535 40608 10 digestive chartreuse4 40608, 3535 10223, 874 10086, 849 10177, 861 10113, 951 0.0379 0.0174 0.0295 1.53 1.04 1 1.07 -0.0131 0.0502 0.794 0.1001 0.987 0.895 1.09 -0.00643 0.05 0.898 0.04688 0.994 0.901 1.1 0.0976 0.0489 0.0462 1.336 1.1 1 1.21 PRS_PLINK_1.99526231496888e.06 574.2 Calculus of bile duct Both 1591 19218 10 digestive chartreuse4 19218, 1591 4818, 390 4824, 381 4786, 373 4789, 447 0.0751 0.0257 0.00353 2.452 1.08 1.02 1.13 -0.0234 0.0748 0.755 0.1222 0.977 0.844 1.13 -0.0348 0.0751 0.643 0.1917 0.966 0.834 1.12 0.156 0.0723 0.0308 1.511 1.17 1.01 1.35 PRS_PLINK_1.99526231496888e.06 574.3 Cholecystitis without cholelithiasis Both 1684 20184 10 digestive chartreuse4 20184, 1684 5044, 389 5072, 446 5020, 410 5044, 438 0.0352 0.0252 0.162 0.7913 1.04 0.986 1.09 0.131 0.0721 0.0684 1.165 1.14 0.99 1.31 0.0615 0.0734 0.402 0.3958 1.06 0.921 1.23 0.129 0.0725 0.0754 1.123 1.14 0.987 1.31 PRS_PLINK_1.99526231496888e.06 575 Other biliary tract disease Both 2417 28197 10 digestive chartreuse4 28197, 2417 7043, 586 7090, 587 7088, 629 6969, 615 0.0376 0.0211 0.075 1.125 1.04 0.996 1.08 -0.00245 0.0607 0.968 0.01418 0.998 0.886 1.12 0.0696 0.0598 0.245 0.611 1.07 0.953 1.21 0.0651 0.0602 0.279 0.5542 1.07 0.949 1.2 PRS_PLINK_1.99526231496888e.06 575.1 Cholangitis Both 246 3359 10 digestive chartreuse4 3359, 246 844, 55 834, 64 838, 70 840, 57 -0.00356 0.0655 0.957 0.01924 0.996 0.876 1.13 0.177 0.188 0.345 0.4616 1.19 0.826 1.73 0.247 0.185 0.181 0.7415 1.28 0.891 1.84 0.0536 0.193 0.781 0.1073 1.06 0.723 1.54 PRS_PLINK_1.99526231496888e.06 575.2 Obstruction of bile duct Both 469 5513 10 digestive chartreuse4 5513, 469 1380, 129 1375, 103 1378, 123 1378, 114 -0.0203 0.0486 0.676 0.1703 0.98 0.891 1.08 -0.218 0.137 0.111 0.9544 0.804 0.615 1.05 -0.0468 0.131 0.721 0.1422 0.954 0.738 1.23 -0.111 0.134 0.407 0.3903 0.895 0.688 1.16 PRS_PLINK_1.99526231496888e.06 575.6 Cholesterolosis of gallbladder Both 329 3555 10 digestive chartreuse4 3555, 329 907, 81 875, 83 886, 92 887, 73 -0.0155 0.0579 0.788 0.1032 0.985 0.879 1.1 0.056 0.162 0.729 0.1371 1.06 0.77 1.45 0.149 0.158 0.348 0.458 1.16 0.85 1.58 -0.0733 0.167 0.661 0.1799 0.929 0.67 1.29 PRS_PLINK_1.99526231496888e.06 575.7 Other disorders of gallbladder Both 903 10419 10 digestive chartreuse4 10419, 903 2611, 227 2612, 217 2623, 226 2571, 233 0.043 0.0345 0.212 0.6728 1.04 0.976 1.12 -0.0442 0.0986 0.654 0.1843 0.957 0.789 1.16 -0.00246 0.0978 0.98 0.008804 0.998 0.824 1.21 0.0454 0.0972 0.641 0.1933 1.05 0.865 1.27 PRS_PLINK_1.99526231496888e.06 575.8 Other disorders of biliary tract Both 629 7533 10 digestive chartreuse4 7533, 629 1882, 155 1885, 143 1883, 158 1881, 173 0.0656 0.0409 0.109 0.9644 1.07 0.986 1.16 -0.0818 0.12 0.495 0.3053 0.921 0.729 1.17 0.0199 0.117 0.865 0.06297 1.02 0.811 1.28 0.108 0.115 0.346 0.4603 1.11 0.889 1.4 PRS_PLINK_1.99526231496888e.06 575.9 Nonspecific abnormal findings on radiological and other examination of biliary tract Both 201 2448 10 digestive chartreuse4 2448, 201 618, 37 609, 48 609, 62 612, 54 0.123 0.071 0.0822 1.085 1.13 0.984 1.3 0.269 0.222 0.226 0.645 1.31 0.846 2.02 0.53 0.213 0.0127 1.897 1.7 1.12 2.58 0.388 0.219 0.0759 1.12 1.47 0.96 2.26 PRS_PLINK_1.99526231496888e.06 577 Diseases of pancreas Both 1539 18975 10 digestive chartreuse4 18975, 1539 4784, 367 4709, 363 4760, 381 4722, 428 0.0765 0.0258 0.00299 2.525 1.08 1.03 1.14 0.00732 0.0767 0.924 0.03435 1.01 0.867 1.17 0.0451 0.0758 0.552 0.2579 1.05 0.902 1.21 0.169 0.074 0.0223 1.651 1.18 1.02 1.37 PRS_PLINK_1.99526231496888e.06 577.1 Acute pancreatitis Both 1156 14294 10 digestive chartreuse4 14294, 1156 3584, 261 3566, 282 3616, 292 3528, 321 0.0967 0.0295 0.00105 2.977 1.1 1.04 1.17 0.0854 0.0889 0.337 0.4727 1.09 0.915 1.3 0.105 0.0882 0.233 0.6321 1.11 0.935 1.32 0.224 0.0865 0.0097 2.013 1.25 1.06 1.48 PRS_PLINK_1.99526231496888e.06 577.2 Chronic pancreatitis Both 289 3652 10 digestive chartreuse4 3652, 289 916, 82 909, 62 913, 75 913, 70 -0.0343 0.0608 0.573 0.2419 0.966 0.858 1.09 -0.271 0.173 0.118 0.9294 0.763 0.543 1.07 -0.086 0.165 0.603 0.2197 0.918 0.664 1.27 -0.136 0.168 0.42 0.3771 0.873 0.628 1.21 PRS_PLINK_1.99526231496888e.06 577.3 Cyst and pseudocyst of pancreas Both 214 2618 10 digestive chartreuse4 2618, 214 660, 57 651, 52 662, 50 645, 55 0.0157 0.0701 0.823 0.08469 1.02 0.885 1.17 -0.0652 0.197 0.741 0.1302 0.937 0.636 1.38 -0.124 0.199 0.532 0.2741 0.883 0.598 1.3 0.00821 0.195 0.966 0.01484 1.01 0.688 1.48 PRS_PLINK_1.99526231496888e.06 578 Gastrointestinal hemorrhage Both 14019 150844 10 digestive chartreuse4 150844, 14019 37976, 3527 37396, 3437 38021, 3538 37400, 3511 0.00965 0.0088 0.273 0.5641 1.01 0.992 1.03 -0.0102 0.025 0.685 0.1645 0.99 0.942 1.04 0.00354 0.0249 0.887 0.05219 1 0.956 1.05 0.0132 0.025 0.598 0.2232 1.01 0.965 1.06 PRS_PLINK_1.99526231496888e.06 578.1 Hematemesis Both 1103 13997 10 digestive chartreuse4 13997, 1103 3537, 295 3460, 258 3499, 276 3498, 274 -0.0235 0.0312 0.451 0.3457 0.977 0.919 1.04 -0.11 0.0884 0.214 0.67 0.896 0.753 1.07 -0.0525 0.0869 0.546 0.263 0.949 0.8 1.13 -0.0528 0.0872 0.545 0.2635 0.949 0.8 1.13 PRS_PLINK_1.99526231496888e.06 578.2 Blood in stool Both 1574 18437 10 digestive chartreuse4 18437, 1574 4607, 407 4609, 370 4605, 410 4608, 384 -0.00565 0.0263 0.83 0.08115 0.994 0.944 1.05 -0.0963 0.0747 0.197 0.7054 0.908 0.785 1.05 0.00965 0.0729 0.895 0.04832 1.01 0.875 1.16 -0.0543 0.0741 0.463 0.3341 0.947 0.819 1.1 PRS_PLINK_1.99526231496888e.06 578.8 Hemorrhage of rectum and anus Both 9164 96331 10 digestive chartreuse4 96331, 9164 24051, 2275 24088, 2271 24464, 2291 23696, 2325 0.0184 0.0109 0.0907 1.042 1.02 0.997 1.04 -0.00293 0.031 0.925 0.034 0.997 0.938 1.06 -0.00863 0.031 0.78 0.1077 0.991 0.933 1.05 0.0379 0.0309 0.22 0.6571 1.04 0.978 1.1 PRS_PLINK_1.99526231496888e.06 578.9 Hemorrhage of gastrointestinal tract Both 3559 38564 10 digestive chartreuse4 38564, 3559 9632, 899 9671, 892 9607, 900 9636, 866 -0.00731 0.0175 0.677 0.1696 0.993 0.959 1.03 -0.0105 0.0494 0.832 0.07982 0.99 0.898 1.09 0.00597 0.0493 0.904 0.04403 1.01 0.913 1.11 -0.0372 0.0498 0.455 0.3423 0.963 0.874 1.06 PRS_PLINK_1.99526231496888e.06 579 Other symptoms involving abdomen and pelvis Both 915 11399 10 digestive chartreuse4 11399, 915 2853, 235 2854, 198 2836, 222 2847, 260 0.055 0.0337 0.102 0.9901 1.06 0.989 1.13 -0.16 0.0998 0.108 0.9646 0.852 0.701 1.04 -0.0437 0.0971 0.652 0.1854 0.957 0.791 1.16 0.13 0.0939 0.168 0.7754 1.14 0.947 1.37 PRS_PLINK_1.99526231496888e.06 579.2 Splenomegaly Both 164 2991 10 digestive chartreuse4 2991, 164 750, 47 748, 25 747, 38 743, 54 0.133 0.0754 0.0775 1.11 1.14 0.985 1.32 -0.628 0.248 0.0112 1.952 0.534 0.328 0.867 -0.209 0.22 0.342 0.4661 0.811 0.527 1.25 0.174 0.204 0.393 0.406 1.19 0.798 1.78 PRS_PLINK_1.99526231496888e.06 579.8 Nonspecific abnormal findings in stool contents Both 1127 11968 10 digestive chartreuse4 11968, 1127 3012, 309 2985, 252 2978, 282 2992, 284 -0.00194 0.0315 0.951 0.02183 0.998 0.938 1.06 -0.192 0.0886 0.0299 1.525 0.825 0.693 0.981 -0.081 0.0863 0.348 0.4585 0.922 0.779 1.09 -0.076 0.0861 0.378 0.4227 0.927 0.783 1.1 PRS_PLINK_1.99526231496888e.06 580 Nephritis; nephrosis; renal sclerosis Both 320 10528 11 genitourinary black 10528, 320 2664, 64 2616, 81 2622, 89 2624, 86 0.11 0.0551 0.0454 1.343 1.12 1 1.24 0.238 0.167 0.155 0.8105 1.27 0.914 1.76 0.358 0.164 0.0295 1.53 1.43 1.04 1.97 0.329 0.166 0.0469 1.329 1.39 1 1.92 PRS_PLINK_1.99526231496888e.06 580.1 Glomerulonephritis Both 189 7088 11 genitourinary black 7088, 189 1776, 34 1779, 48 1760, 56 1772, 51 0.14 0.0709 0.048 1.318 1.15 1 1.32 0.331 0.222 0.135 0.8681 1.39 0.902 2.15 0.516 0.215 0.0166 1.78 1.68 1.1 2.56 0.43 0.219 0.0501 1.3 1.54 1 2.36 PRS_PLINK_1.99526231496888e.06 580.11 Proliferative glomerulonephritis Both 18 560 11 genitourinary black 560, 18 142, 2 139, 4 140, 8 139, 4 0.0987 0.215 0.647 0.1893 1.1 0.724 1.68 0.549 0.693 0.429 0.368 1.73 0.445 6.74 1.04 0.659 0.115 0.9392 2.82 0.776 10.3 0.497 0.682 0.466 0.3312 1.64 0.432 6.26 PRS_PLINK_1.99526231496888e.06 580.12 Non-proliferative glomerulonephritis Both 37 957 11 genitourinary black 957, 37 240, 5 240, 12 241, 13 236, 7 -0.0252 0.16 0.875 0.05805 0.975 0.713 1.33 0.85 0.484 0.079 1.103 2.34 0.906 6.04 0.893 0.482 0.0638 1.195 2.44 0.95 6.27 0.282 0.521 0.588 0.2306 1.33 0.478 3.68 PRS_PLINK_1.99526231496888e.06 580.14 Chronic glomerulonephritis, NOS Both 140 5813 11 genitourinary black 5813, 140 1472, 27 1439, 34 1450, 41 1451, 38 0.178 0.0813 0.0283 1.549 1.2 1.02 1.4 0.242 0.253 0.338 0.4705 1.27 0.776 2.09 0.429 0.244 0.0789 1.103 1.54 0.952 2.48 0.372 0.247 0.133 0.8776 1.45 0.893 2.36 PRS_PLINK_1.99526231496888e.06 580.2 Nephrotic syndrome without mention of glomerulonephritis Both 113 3276 11 genitourinary black 3276, 113 821, 23 821, 23 815, 33 819, 34 0.122 0.091 0.181 0.7414 1.13 0.945 1.35 -0.012 0.287 0.967 0.01472 0.988 0.563 1.74 0.353 0.267 0.186 0.7295 1.42 0.843 2.4 0.388 0.266 0.145 0.8387 1.47 0.875 2.48 PRS_PLINK_1.99526231496888e.06 580.3 Nephritis and nephropathy without mention of glomerulonephritis Both 66 1741 11 genitourinary black 1741, 66 437, 14 434, 22 443, 15 426, 15 -0.0178 0.123 0.885 0.05288 0.982 0.772 1.25 0.455 0.333 0.173 0.7623 1.58 0.82 3.03 0.0656 0.356 0.853 0.0688 1.07 0.532 2.14 0.117 0.357 0.742 0.1294 1.12 0.559 2.26 PRS_PLINK_1.99526231496888e.06 580.32 Nephritis and nephropathy with pathological lesion Both 67 1798 11 genitourinary black 1798, 67 454, 15 450, 21 444, 16 450, 15 -0.0342 0.122 0.78 0.108 0.966 0.76 1.23 0.337 0.329 0.306 0.5144 1.4 0.735 2.67 0.123 0.347 0.723 0.1407 1.13 0.573 2.23 0.0457 0.351 0.896 0.04751 1.05 0.526 2.08 PRS_PLINK_1.99526231496888e.06 585 Renal failure Both 2224 47440 11 genitourinary black 47440, 2224 11909, 527 11823, 524 11876, 560 11816, 613 0.0719 0.0212 0.000679 3.168 1.07 1.03 1.12 0.00437 0.063 0.945 0.02474 1 0.888 1.14 0.0705 0.062 0.256 0.5923 1.07 0.95 1.21 0.17 0.0608 0.00519 2.285 1.19 1.05 1.34 PRS_PLINK_1.99526231496888e.06 585.1 Acute renal failure Both 1647 30586 11 genitourinary black 30586, 1647 7636, 394 7651, 405 7672, 404 7616, 444 0.0526 0.0249 0.0348 1.458 1.05 1 1.11 0.0291 0.0725 0.688 0.1623 1.03 0.893 1.19 0.0281 0.0725 0.699 0.1558 1.03 0.892 1.19 0.137 0.0711 0.0535 1.271 1.15 0.998 1.32 PRS_PLINK_1.99526231496888e.06 585.2 Renal failure NOS Both 407 10013 11 genitourinary black 10013, 407 2535, 96 2476, 95 2540, 103 2462, 113 0.0816 0.0481 0.0901 1.045 1.08 0.987 1.19 0.0149 0.146 0.919 0.03683 1.02 0.762 1.35 0.0721 0.143 0.615 0.2109 1.07 0.811 1.42 0.196 0.141 0.164 0.7852 1.22 0.923 1.6 PRS_PLINK_1.99526231496888e.06 585.3 Chronic renal failure [CKD] Both 445 17878 11 genitourinary black 17878, 445 4466, 103 4471, 99 4489, 118 4447, 125 0.103 0.0463 0.0262 1.582 1.11 1.01 1.21 -0.0371 0.141 0.793 0.1009 0.964 0.731 1.27 0.139 0.135 0.305 0.5152 1.15 0.881 1.5 0.206 0.134 0.123 0.9092 1.23 0.946 1.6 PRS_PLINK_1.99526231496888e.06 585.31 Renal dialysis Both 67 3525 11 genitourinary black 3525, 67 882, 15 884, 11 889, 20 870, 21 0.166 0.114 0.146 0.8351 1.18 0.944 1.48 -0.3 0.371 0.419 0.3776 0.741 0.358 1.53 0.314 0.327 0.337 0.4728 1.37 0.721 2.6 0.314 0.324 0.332 0.4792 1.37 0.726 2.58 PRS_PLINK_1.99526231496888e.06 586 Other disorders of the kidney and ureters Both 1613 23513 11 genitourinary black 23513, 1613 5893, 397 5865, 392 5870, 411 5876, 413 0.0349 0.0253 0.169 0.7729 1.04 0.985 1.09 -0.00877 0.0734 0.905 0.04338 0.991 0.858 1.14 0.0445 0.0727 0.541 0.2671 1.05 0.907 1.21 0.0465 0.0726 0.522 0.2825 1.05 0.909 1.21 PRS_PLINK_1.99526231496888e.06 586.1 Anatomical abnormatilies of kidney and ureters Both 46 1460 11 genitourinary black 1460, 46 366, 11 365, 11 365, 12 364, 12 0.0827 0.137 0.547 0.262 1.09 0.83 1.42 0.0683 0.404 0.866 0.06263 1.07 0.485 2.36 0.135 0.398 0.734 0.1345 1.15 0.525 2.5 0.127 0.395 0.747 0.1266 1.14 0.524 2.46 PRS_PLINK_1.99526231496888e.06 586.11 Small kidney Both 38 1242 11 genitourinary black 1242, 38 314, 10 308, 7 310, 11 310, 10 0.159 0.149 0.286 0.543 1.17 0.875 1.57 -0.204 0.458 0.656 0.1831 0.815 0.332 2 0.137 0.417 0.742 0.1296 1.15 0.507 2.6 0.0566 0.419 0.893 0.04932 1.06 0.465 2.41 PRS_PLINK_1.99526231496888e.06 586.2 Cyst of kidney, acquired Both 653 8642 11 genitourinary black 8642, 653 2165, 161 2164, 149 2165, 168 2147, 175 0.0401 0.0398 0.314 0.5028 1.04 0.963 1.13 -0.0854 0.117 0.466 0.3316 0.918 0.73 1.16 0.0448 0.114 0.694 0.1586 1.05 0.837 1.31 0.0944 0.113 0.404 0.3935 1.1 0.88 1.37 PRS_PLINK_1.99526231496888e.06 586.3 Vascular disorders of kidney/hypertrophy Both 26 569 11 genitourinary black 569, 26 145, 4 140, 7 145, 9 139, 6 0.109 0.185 0.557 0.2539 1.11 0.775 1.6 0.541 0.551 0.326 0.4869 1.72 0.584 5.06 0.696 0.546 0.203 0.6929 2.01 0.687 5.85 0.386 0.567 0.496 0.3044 1.47 0.484 4.47 PRS_PLINK_1.99526231496888e.06 586.4 Stricture/obstruction of ureter Both 473 6532 11 genitourinary black 6532, 473 1640, 112 1627, 125 1649, 120 1614, 116 0.0288 0.0473 0.542 0.266 1.03 0.938 1.13 0.118 0.134 0.379 0.4215 1.13 0.865 1.46 0.0751 0.135 0.579 0.2374 1.08 0.827 1.41 0.0616 0.137 0.652 0.1856 1.06 0.814 1.39 PRS_PLINK_1.99526231496888e.06 587 Kidney replaced by transpant Both 24 2697 11 genitourinary black 2697, 24 676, 4 674, 4 678, 8 669, 8 0.221 0.179 0.218 0.6625 1.25 0.878 1.77 0.0426 0.578 0.941 0.02629 1.04 0.336 3.24 0.661 0.524 0.208 0.6829 1.94 0.693 5.41 0.613 0.525 0.242 0.6154 1.85 0.66 5.16 PRS_PLINK_1.99526231496888e.06 588 Disorders resulting from impaired renal function Both 21 735 11 genitourinary black 735, 21 184, 3 184, 6 183, 7 184, 5 -0.0129 0.218 0.953 0.02095 0.987 0.644 1.51 0.442 0.601 0.462 0.335 1.56 0.479 5.05 0.595 0.59 0.314 0.5036 1.81 0.57 5.76 0.432 0.627 0.491 0.3094 1.54 0.451 5.27 PRS_PLINK_1.99526231496888e.06 589 Abnormal results of function study of kidney Both 42 808 11 genitourinary black 808, 42 204, 12 201, 15 201, 7 202, 8 -0.129 0.156 0.409 0.3884 0.879 0.648 1.19 0.259 0.386 0.501 0.2999 1.3 0.609 2.76 -0.459 0.447 0.304 0.517 0.632 0.263 1.52 -0.389 0.434 0.37 0.4315 0.678 0.289 1.59 PRS_PLINK_1.99526231496888e.06 590 Pyelonephritis Both 801 10146 11 genitourinary black 10146, 801 2549, 205 2542, 184 2531, 203 2520, 209 0.0322 0.0365 0.378 0.4228 1.03 0.961 1.11 -0.105 0.105 0.317 0.4995 0.9 0.733 1.11 -0.00292 0.103 0.977 0.009959 0.997 0.815 1.22 0.0438 0.102 0.668 0.175 1.04 0.855 1.28 PRS_PLINK_1.99526231496888e.06 591 Urinary tract infection Both 7516 88690 11 genitourinary black 88690, 7516 22331, 1843 22092, 1932 22113, 1908 22124, 1830 -5.81e-05 0.012 0.996 0.001683 1 0.977 1.02 0.0589 0.0339 0.0826 1.083 1.06 0.992 1.13 0.0481 0.034 0.157 0.8036 1.05 0.982 1.12 0.00709 0.0344 0.837 0.0774 1.01 0.941 1.08 PRS_PLINK_1.99526231496888e.06 592 Cystitis and urethritis Both 1928 21171 11 genitourinary black 21171, 1928 5299, 471 5291, 475 5280, 481 5293, 501 0.0175 0.0234 0.455 0.3416 1.02 0.972 1.07 0.00951 0.0678 0.888 0.05137 1.01 0.884 1.15 0.024 0.0676 0.723 0.1408 1.02 0.897 1.17 0.0653 0.0671 0.331 0.4802 1.07 0.936 1.22 PRS_PLINK_1.99526231496888e.06 592.1 Cystitis Both 1886 20769 11 genitourinary black 20769, 1886 5198, 461 5189, 476 5185, 472 5190, 477 0.00794 0.0238 0.738 0.1317 1.01 0.962 1.06 0.0335 0.0681 0.623 0.2058 1.03 0.905 1.18 0.0261 0.0683 0.703 0.1533 1.03 0.898 1.17 0.0383 0.0683 0.575 0.2405 1.04 0.909 1.19 PRS_PLINK_1.99526231496888e.06 592.11 Acute cystitis Both 86 944 11 genitourinary black 944, 86 238, 29 234, 13 236, 21 236, 23 -0.0378 0.112 0.736 0.1334 0.963 0.773 1.2 -0.827 0.339 0.0146 1.835 0.437 0.225 0.85 -0.34 0.295 0.249 0.603 0.712 0.399 1.27 -0.235 0.29 0.417 0.3798 0.79 0.448 1.4 PRS_PLINK_1.99526231496888e.06 592.12 Chronic cystitis Both 577 6386 11 genitourinary black 6386, 577 1602, 145 1592, 146 1599, 145 1590, 141 -0.0228 0.0436 0.6 0.2215 0.977 0.897 1.06 0.0157 0.122 0.898 0.04688 1.02 0.8 1.29 0.00449 0.122 0.971 0.01293 1 0.791 1.28 -0.0101 0.123 0.935 0.02932 0.99 0.777 1.26 PRS_PLINK_1.99526231496888e.06 592.13 Chronic interstitial cystitis Both 173 1820 11 genitourinary black 1820, 173 456, 46 453, 45 461, 36 449, 46 0.0346 0.0789 0.661 0.18 1.04 0.887 1.21 -0.016 0.216 0.941 0.0264 0.984 0.644 1.5 -0.261 0.229 0.254 0.5951 0.77 0.492 1.21 0.03 0.216 0.889 0.05088 1.03 0.675 1.57 PRS_PLINK_1.99526231496888e.06 592.2 Urethritis and urethral syndrome Both 121 1186 11 genitourinary black 1186, 121 300, 30 291, 21 296, 33 297, 37 0.136 0.0893 0.129 0.8902 1.15 0.961 1.36 -0.334 0.291 0.251 0.6001 0.716 0.405 1.27 0.124 0.261 0.636 0.1968 1.13 0.679 1.89 0.236 0.256 0.357 0.4471 1.27 0.766 2.09 PRS_PLINK_1.99526231496888e.06 593 Hematuria Both 10355 112993 11 genitourinary black 112993, 10355 28231, 2533 28233, 2717 28332, 2628 28163, 2474 -0.0079 0.0103 0.441 0.3553 0.992 0.972 1.01 0.0705 0.0289 0.0147 1.834 1.07 1.01 1.14 0.0333 0.0291 0.252 0.598 1.03 0.977 1.09 -0.0187 0.0295 0.527 0.2783 0.981 0.926 1.04 PRS_PLINK_1.99526231496888e.06 594 Urinary calculus Both 3976 45158 11 genitourinary black 45158, 3976 11280, 971 11348, 1070 11269, 956 11251, 979 -0.00292 0.0165 0.859 0.0659 0.997 0.965 1.03 0.0915 0.0463 0.0478 1.32 1.1 1 1.2 -0.0118 0.0475 0.804 0.09487 0.988 0.9 1.08 0.0142 0.0472 0.763 0.1172 1.01 0.925 1.11 PRS_PLINK_1.99526231496888e.06 594.1 Calculus of kidney Both 1936 22297 11 genitourinary black 22297, 1936 5591, 428 5579, 536 5554, 464 5567, 508 0.0461 0.0231 0.0463 1.334 1.05 1 1.1 0.228 0.0675 0.000714 3.146 1.26 1.1 1.43 0.0933 0.0696 0.18 0.7454 1.1 0.958 1.26 0.178 0.0682 0.009 2.046 1.2 1.05 1.37 PRS_PLINK_1.99526231496888e.06 594.2 Calculus of lower urinary tract Both 430 5060 11 genitourinary black 5060, 430 1269, 112 1266, 122 1270, 99 1252, 97 -0.076 0.0504 0.131 0.8818 0.927 0.84 1.02 0.0857 0.136 0.529 0.2766 1.09 0.834 1.42 -0.119 0.143 0.404 0.3939 0.888 0.671 1.17 -0.126 0.143 0.381 0.4192 0.882 0.666 1.17 PRS_PLINK_1.99526231496888e.06 594.3 Calculus of ureter Both 1479 17012 11 genitourinary black 17012, 1479 4269, 370 4266, 389 4228, 335 4244, 385 0.00465 0.0269 0.863 0.06411 1 0.953 1.06 0.0526 0.0757 0.487 0.3122 1.05 0.909 1.22 -0.0863 0.0784 0.271 0.5671 0.917 0.787 1.07 0.0487 0.076 0.521 0.2828 1.05 0.905 1.22 PRS_PLINK_1.99526231496888e.06 594.8 Renal colic Both 1333 14789 11 genitourinary black 14789, 1333 3693, 355 3729, 325 3684, 351 3677, 302 -0.024 0.0286 0.402 0.3955 0.976 0.923 1.03 -0.101 0.0801 0.207 0.6848 0.904 0.772 1.06 -0.00344 0.0787 0.965 0.01539 0.997 0.854 1.16 -0.153 0.0816 0.0617 1.21 0.859 0.732 1.01 PRS_PLINK_1.99526231496888e.06 595 Hydronephrosis Both 1061 13692 11 genitourinary black 13692, 1061 3476, 270 3380, 258 3454, 254 3380, 279 0.0122 0.0318 0.7 0.155 1.01 0.951 1.08 -0.0128 0.0902 0.887 0.05205 0.987 0.827 1.18 -0.0416 0.0906 0.646 0.1899 0.959 0.803 1.15 0.0657 0.0887 0.459 0.3385 1.07 0.898 1.27 PRS_PLINK_1.99526231496888e.06 596 Other disorders of bladder Both 6147 66514 11 genitourinary black 66514, 6147 16637, 1520 16619, 1527 16597, 1515 16627, 1584 0.0177 0.0132 0.179 0.7462 1.02 0.992 1.04 0.00622 0.0378 0.869 0.06076 1.01 0.934 1.08 -0.00134 0.0379 0.972 0.01239 0.999 0.927 1.08 0.041 0.0376 0.276 0.5594 1.04 0.968 1.12 PRS_PLINK_1.99526231496888e.06 596.1 Bladder neck obstruction Both 1187 12461 11 genitourinary black 12461, 1187 3112, 300 3112, 302 3162, 310 3068, 275 -0.0252 0.0303 0.405 0.393 0.975 0.919 1.03 0.00889 0.0852 0.917 0.03768 1.01 0.854 1.19 0.0211 0.0847 0.803 0.09502 1.02 0.865 1.21 -0.0763 0.0872 0.382 0.418 0.927 0.781 1.1 PRS_PLINK_1.99526231496888e.06 596.5 Functional disorders of bladder Both 1093 12035 11 genitourinary black 12035, 1093 3064, 299 2969, 263 2997, 245 2999, 286 0.00323 0.0314 0.918 0.03718 1 0.943 1.07 -0.0936 0.0882 0.289 0.5397 0.911 0.766 1.08 -0.181 0.0898 0.0439 1.358 0.835 0.7 0.995 -0.0223 0.0866 0.797 0.09864 0.978 0.825 1.16 PRS_PLINK_1.99526231496888e.06 597 Other disorders of urethra and urinary tract Both 2569 27514 11 genitourinary black 27514, 2569 6918, 628 6824, 630 6928, 661 6829, 648 0.0186 0.0206 0.367 0.4359 1.02 0.978 1.06 0.0169 0.0589 0.774 0.1115 1.02 0.906 1.14 0.0503 0.0582 0.388 0.4113 1.05 0.938 1.18 0.0464 0.0586 0.428 0.3682 1.05 0.934 1.17 PRS_PLINK_1.99526231496888e.06 597.1 Urethral stricture (not specified as infectious) Both 2151 23144 11 genitourinary black 23144, 2151 5774, 521 5801, 544 5770, 539 5786, 545 0.013 0.0225 0.562 0.2505 1.01 0.969 1.06 0.0393 0.064 0.539 0.2681 1.04 0.917 1.18 0.0349 0.0641 0.586 0.2319 1.04 0.913 1.17 0.0451 0.0641 0.481 0.3175 1.05 0.923 1.19 PRS_PLINK_1.99526231496888e.06 597.2 Urinary complications NEC Both 38 544 11 genitourinary black 544, 38 141, 11 131, 8 136, 8 136, 11 0.136 0.158 0.389 0.4101 1.15 0.841 1.56 -0.22 0.459 0.632 0.1994 0.803 0.326 1.97 -0.243 0.456 0.595 0.2254 0.785 0.321 1.92 0.0999 0.421 0.813 0.09013 1.11 0.484 2.52 PRS_PLINK_1.99526231496888e.06 598 Abnormal findings on examination of urine Both 2262 24317 11 genitourinary black 24317, 2262 6085, 578 6087, 580 6067, 535 6070, 567 -0.013 0.022 0.554 0.2564 0.987 0.946 1.03 0.00426 0.0614 0.945 0.02472 1 0.89 1.13 -0.0731 0.0626 0.243 0.6148 0.929 0.822 1.05 -0.00969 0.0619 0.876 0.05772 0.99 0.877 1.12 PRS_PLINK_1.99526231496888e.06 598.9 Other nonspecific findings on examination of urine Both 158 2095 11 genitourinary black 2095, 158 526, 49 522, 41 522, 36 524, 32 -0.13 0.0841 0.122 0.9124 0.878 0.745 1.04 -0.129 0.219 0.554 0.2566 0.879 0.572 1.35 -0.283 0.225 0.208 0.6827 0.753 0.485 1.17 -0.406 0.232 0.08 1.097 0.666 0.423 1.05 PRS_PLINK_1.99526231496888e.06 599 Other symptoms/disorders or the urinary system Both 12379 133880 11 genitourinary black 133880, 12379 33711, 3071 33184, 3141 33706, 3048 33230, 3114 0.00597 0.00938 0.525 0.2801 1.01 0.988 1.02 0.0387 0.0265 0.145 0.8383 1.04 0.987 1.09 -0.0063 0.0267 0.814 0.08959 0.994 0.943 1.05 0.0318 0.0266 0.233 0.6327 1.03 0.98 1.09 PRS_PLINK_1.99526231496888e.06 599.1 Urinary obstruction Both 79 1139 11 genitourinary black 1139, 79 286, 16 284, 23 283, 22 285, 18 0.0602 0.113 0.596 0.2249 1.06 0.85 1.33 0.362 0.327 0.269 0.5702 1.44 0.756 2.73 0.303 0.327 0.355 0.4497 1.35 0.713 2.57 0.114 0.345 0.741 0.13 1.12 0.57 2.21 PRS_PLINK_1.99526231496888e.06 599.2 Retention of urine Both 3915 44012 11 genitourinary black 44012, 3915 10986, 930 11027, 975 10982, 986 10998, 1021 0.031 0.0164 0.0581 1.236 1.03 0.999 1.07 0.044 0.0477 0.357 0.4473 1.04 0.952 1.15 0.0596 0.0476 0.211 0.6758 1.06 0.967 1.17 0.0892 0.0473 0.0596 1.225 1.09 0.996 1.2 PRS_PLINK_1.99526231496888e.06 599.3 Dysuria Both 767 8611 11 genitourinary black 8611, 767 2152, 187 2162, 184 2148, 208 2148, 188 -0.00384 0.0383 0.92 0.03621 0.996 0.924 1.07 -0.0208 0.108 0.847 0.07195 0.979 0.793 1.21 0.111 0.105 0.292 0.5344 1.12 0.909 1.37 0.00854 0.108 0.937 0.02842 1.01 0.817 1.25 PRS_PLINK_1.99526231496888e.06 599.4 Urinary incontinence Both 6225 66676 11 genitourinary black 66676, 6225 16767, 1530 16591, 1621 16733, 1516 16562, 1556 0.00495 0.0133 0.709 0.1492 1 0.979 1.03 0.0692 0.0373 0.0636 1.197 1.07 0.996 1.15 -0.00554 0.0378 0.884 0.0537 0.994 0.923 1.07 0.0338 0.0377 0.369 0.4328 1.03 0.961 1.11 PRS_PLINK_1.99526231496888e.06 599.5 Frequency of urination and polyuria Both 2659 28363 11 genitourinary black 28363, 2659 7077, 662 7096, 661 7116, 656 7059, 679 0.0124 0.0201 0.537 0.2701 1.01 0.973 1.05 -0.0037 0.0575 0.949 0.02287 0.996 0.89 1.12 -0.0153 0.0576 0.791 0.102 0.985 0.88 1.1 0.0267 0.0573 0.641 0.1932 1.03 0.918 1.15 PRS_PLINK_1.99526231496888e.06 599.6 Oliguria and anuria Both 37 695 11 genitourinary black 695, 37 175, 10 172, 8 174, 11 173, 8 0.0993 0.156 0.524 0.2807 1.1 0.814 1.5 -0.342 0.458 0.455 0.3419 0.711 0.29 1.74 0.125 0.421 0.766 0.1157 1.13 0.497 2.58 -0.207 0.451 0.647 0.1894 0.813 0.336 1.97 PRS_PLINK_1.99526231496888e.06 599.8 Other symptoms involving urinary system Both 37 432 11 genitourinary black 432, 37 109, 11 107, 9 108, 9 108, 8 -0.072 0.169 0.67 0.1742 0.931 0.669 1.3 -0.144 0.444 0.745 0.1279 0.866 0.363 2.06 -0.0777 0.442 0.861 0.06524 0.925 0.389 2.2 -0.442 0.461 0.338 0.4716 0.643 0.261 1.59 PRS_PLINK_1.99526231496888e.06 599.9 Other abnormality of urination Both 1246 13115 11 genitourinary black 13115, 1246 3277, 308 3303, 300 3268, 294 3265, 342 0.038 0.0292 0.193 0.7149 1.04 0.981 1.1 -0.0329 0.0846 0.698 0.1563 0.968 0.82 1.14 -0.0408 0.085 0.631 0.1999 0.96 0.813 1.13 0.111 0.0823 0.177 0.7531 1.12 0.951 1.31 PRS_PLINK_1.99526231496888e.06 600 Hyperplasia of prostate Male 6386 55946 11 genitourinary black 55946, 6386 14028, 1560 14004, 1600 14085, 1639 13807, 1584 0.00467 0.013 0.719 0.1434 1 0.979 1.03 0.026 0.0376 0.49 0.3101 1.03 0.953 1.1 0.0353 0.0374 0.346 0.4611 1.04 0.963 1.11 0.0134 0.0377 0.723 0.1407 1.01 0.941 1.09 PRS_PLINK_1.99526231496888e.06 601 Inflammatory diseases of prostate Male 1239 13404 11 genitourinary black 13404, 1239 3355, 319 3365, 285 3374, 315 3303, 319 0.0201 0.0291 0.49 0.3102 1.02 0.964 1.08 -0.112 0.085 0.186 0.7296 0.894 0.757 1.06 -0.0121 0.083 0.884 0.05374 0.988 0.84 1.16 0.0137 0.0828 0.868 0.06139 1.01 0.862 1.19 PRS_PLINK_1.99526231496888e.06 601.1 Prostatitis Male 935 9926 11 genitourinary black 9926, 935 2493, 235 2465, 201 2487, 231 2476, 267 0.0621 0.0332 0.0612 1.213 1.06 0.997 1.14 -0.142 0.1 0.157 0.8051 0.868 0.714 1.06 -0.00951 0.0968 0.922 0.03539 0.991 0.819 1.2 0.138 0.0938 0.14 0.8527 1.15 0.955 1.38 PRS_PLINK_1.99526231496888e.06 601.11 Acute prostatitis Male 135 1527 11 genitourinary black 1527, 135 380, 30 381, 37 382, 34 381, 34 0.0182 0.0861 0.833 0.07957 1.02 0.86 1.21 0.222 0.252 0.379 0.4216 1.25 0.762 2.05 0.151 0.256 0.557 0.2544 1.16 0.703 1.92 0.108 0.255 0.671 0.1731 1.11 0.676 1.84 PRS_PLINK_1.99526231496888e.06 601.12 Chronic prostatitis Male 548 5689 11 genitourinary black 5689, 548 1425, 137 1416, 126 1433, 131 1411, 153 0.0437 0.0436 0.316 0.5002 1.04 0.959 1.14 -0.0759 0.129 0.555 0.2557 0.927 0.721 1.19 -0.0394 0.128 0.757 0.1207 0.961 0.749 1.23 0.123 0.123 0.318 0.4978 1.13 0.888 1.44 PRS_PLINK_1.99526231496888e.06 601.3 Orchitis and epididymitis Male 45 421 11 genitourinary black 421, 45 106, 11 105, 9 105, 9 105, 16 0.0876 0.149 0.556 0.255 1.09 0.815 1.46 -0.166 0.45 0.713 0.147 0.847 0.351 2.05 -0.131 0.45 0.771 0.1131 0.877 0.363 2.12 0.329 0.405 0.417 0.3804 1.39 0.628 3.08 PRS_PLINK_1.99526231496888e.06 601.4 Balanoposthitis Male 179 1907 11 genitourinary black 1907, 179 478, 41 476, 53 484, 40 469, 45 0.00908 0.0764 0.905 0.04314 1.01 0.869 1.17 0.239 0.216 0.269 0.5703 1.27 0.831 1.94 -0.0539 0.228 0.813 0.08975 0.947 0.606 1.48 0.144 0.224 0.521 0.2834 1.15 0.745 1.79 PRS_PLINK_1.99526231496888e.06 601.8 Other inflammatory disorders of male genital organs Male 168 2013 11 genitourinary black 2013, 168 503, 50 503, 42 503, 39 503, 37 -0.0873 0.0825 0.29 0.5377 0.916 0.78 1.08 -0.152 0.217 0.482 0.3172 0.859 0.562 1.31 -0.23 0.22 0.296 0.5287 0.795 0.516 1.22 -0.305 0.223 0.173 0.7623 0.737 0.476 1.14 PRS_PLINK_1.99526231496888e.06 602 Other disorders of prostate Male 787 8223 11 genitourinary black 8223, 787 2061, 181 2053, 203 2053, 193 2053, 209 0.0319 0.0361 0.377 0.4241 1.03 0.962 1.11 0.117 0.107 0.272 0.5658 1.12 0.912 1.39 0.0627 0.108 0.561 0.2512 1.06 0.862 1.32 0.145 0.106 0.171 0.766 1.16 0.939 1.42 PRS_PLINK_1.99526231496888e.06 603 Other disorders of testis Male 1349 14624 11 genitourinary black 14624, 1349 3653, 347 3672, 327 3645, 334 3650, 339 -0.0168 0.0284 0.555 0.2559 0.983 0.93 1.04 -0.0627 0.0804 0.435 0.3612 0.939 0.802 1.1 -0.0338 0.0801 0.673 0.1722 0.967 0.826 1.13 -0.0143 0.0798 0.858 0.06673 0.986 0.843 1.15 PRS_PLINK_1.99526231496888e.06 603.1 Hydrocele Male 832 8911 11 genitourinary black 8911, 832 2230, 216 2237, 215 2215, 195 2228, 204 -0.0334 0.0361 0.355 0.4493 0.967 0.901 1.04 -0.0071 0.101 0.944 0.02515 0.993 0.815 1.21 -0.0953 0.103 0.355 0.4498 0.909 0.743 1.11 -0.0446 0.102 0.662 0.1793 0.956 0.783 1.17 PRS_PLINK_1.99526231496888e.06 604 Disorders of penis Male 2065 22593 11 genitourinary black 22593, 2065 5692, 487 5604, 517 5642, 568 5648, 493 0.0211 0.0227 0.355 0.4503 1.02 0.977 1.07 0.0757 0.0658 0.25 0.6014 1.08 0.948 1.23 0.164 0.0645 0.011 1.961 1.18 1.04 1.34 0.0203 0.0666 0.76 0.1192 1.02 0.896 1.16 PRS_PLINK_1.99526231496888e.06 604.1 Redundant prepuce and phimosis/BXO Male 1692 18724 11 genitourinary black 18724, 1692 4677, 398 4703, 444 4662, 455 4678, 395 0.00154 0.0252 0.951 0.02168 1 0.953 1.05 0.103 0.072 0.152 0.8171 1.11 0.963 1.28 0.138 0.0716 0.0544 1.265 1.15 0.997 1.32 -0.00577 0.0739 0.938 0.0279 0.994 0.86 1.15 PRS_PLINK_1.99526231496888e.06 605 Erectile dysfunction [ED] Male 168 1816 11 genitourinary black 1816, 168 454, 42 454, 45 456, 36 452, 45 0.0306 0.0778 0.694 0.1586 1.03 0.885 1.2 0.0641 0.222 0.773 0.112 1.07 0.69 1.65 -0.19 0.234 0.418 0.3791 0.827 0.523 1.31 0.0529 0.222 0.812 0.09046 1.05 0.682 1.63 PRS_PLINK_1.99526231496888e.06 608 Other disorders of male genital organs Male 1823 19075 11 genitourinary black 19075, 1823 4846, 447 4709, 469 4748, 414 4767, 491 0.0317 0.0241 0.189 0.7236 1.03 0.985 1.08 0.0772 0.0691 0.264 0.578 1.08 0.943 1.24 -0.0566 0.0711 0.426 0.3708 0.945 0.822 1.09 0.109 0.0684 0.11 0.9577 1.12 0.975 1.28 PRS_PLINK_1.99526231496888e.06 609 Male infertility and abnormal spermatozoa Male 135 1361 11 genitourinary black 1361, 135 342, 33 339, 36 340, 36 340, 30 -0.0603 0.0878 0.492 0.3081 0.941 0.793 1.12 0.0969 0.248 0.696 0.1571 1.1 0.677 1.79 0.0971 0.249 0.696 0.1572 1.1 0.677 1.79 -0.0622 0.26 0.811 0.09094 0.94 0.564 1.56 PRS_PLINK_1.99526231496888e.06 609.1 Infertility, male Male 49 503 11 genitourinary black 503, 49 125, 13 127, 11 124, 12 126, 13 0.0341 0.144 0.813 0.08974 1.03 0.78 1.37 -0.157 0.408 0.701 0.1545 0.855 0.384 1.9 0.0692 0.413 0.867 0.062 1.07 0.477 2.41 -0.0526 0.4 0.895 0.04801 0.949 0.433 2.08 PRS_PLINK_1.99526231496888e.06 609.2 Abnormal spermatozoa Male 99 1002 11 genitourinary black 1002, 99 252, 22 249, 29 251, 26 250, 22 -0.079 0.102 0.439 0.3573 0.924 0.757 1.13 0.287 0.289 0.321 0.4936 1.33 0.756 2.35 0.173 0.298 0.562 0.2504 1.19 0.663 2.13 0.0354 0.309 0.909 0.04156 1.04 0.566 1.9 PRS_PLINK_1.99526231496888e.06 610 Benign mammary dysplasias Female 1972 19921 11 genitourinary black 19921, 1972 5103, 496 4864, 504 5003, 497 4948, 472 -0.0144 0.0238 0.545 0.2636 0.986 0.941 1.03 0.0612 0.0663 0.356 0.4485 1.06 0.934 1.21 0.024 0.0665 0.718 0.144 1.02 0.899 1.17 -0.0155 0.0673 0.818 0.0873 0.985 0.863 1.12 PRS_PLINK_1.99526231496888e.06 610.1 Cystic mastopathy Female 722 7285 11 genitourinary black 7285, 722 1854, 174 1798, 194 1816, 179 1813, 174 -0.00631 0.0392 0.872 0.05936 0.994 0.92 1.07 0.135 0.109 0.217 0.663 1.14 0.924 1.42 0.0462 0.111 0.678 0.1688 1.05 0.842 1.3 0.0273 0.112 0.807 0.09301 1.03 0.825 1.28 PRS_PLINK_1.99526231496888e.06 610.2 Fibroadenosis of breast Female 238 2420 11 genitourinary black 2420, 238 630, 59 585, 53 602, 70 603, 55 0.0286 0.0679 0.673 0.1718 1.03 0.901 1.18 -0.0403 0.196 0.837 0.07724 0.961 0.654 1.41 0.211 0.185 0.252 0.5988 1.24 0.86 1.77 -0.0294 0.195 0.88 0.05556 0.971 0.663 1.42 PRS_PLINK_1.99526231496888e.06 610.3 Fibrosclerosis of breast Female 235 2364 11 genitourinary black 2364, 235 594, 55 592, 68 588, 57 590, 55 -0.038 0.0701 0.587 0.2311 0.963 0.839 1.1 0.205 0.189 0.277 0.5573 1.23 0.848 1.78 0.0556 0.196 0.777 0.1097 1.06 0.72 1.55 -0.00736 0.198 0.97 0.01309 0.993 0.674 1.46 PRS_PLINK_1.99526231496888e.06 610.4 Benign neoplasm of breast Female 1121 11242 11 genitourinary black 11242, 1121 2856, 295 2786, 289 2803, 264 2793, 272 -0.0293 0.0317 0.354 0.4505 0.971 0.913 1.03 0.0016 0.0869 0.985 0.006434 1 0.845 1.19 -0.0864 0.0886 0.33 0.4819 0.917 0.771 1.09 -0.0596 0.0881 0.499 0.3022 0.942 0.793 1.12 PRS_PLINK_1.99526231496888e.06 610.8 Other specified benign mammary dysplasias Female 522 5394 11 genitourinary black 5394, 522 1360, 135 1339, 120 1356, 139 1338, 128 0.00889 0.0468 0.849 0.07099 1.01 0.921 1.11 -0.103 0.131 0.429 0.3675 0.902 0.698 1.17 0.0236 0.126 0.852 0.06951 1.02 0.799 1.31 -0.0426 0.129 0.741 0.1301 0.958 0.744 1.23 PRS_PLINK_1.99526231496888e.06 611 Abnormal findings on mammogram or breast exam Both 1239 12358 11 genitourinary black 12358, 1239 3090, 309 3102, 304 3106, 293 3058, 332 0.0245 0.0297 0.41 0.3876 1.02 0.967 1.09 -0.0204 0.0846 0.809 0.0921 0.98 0.83 1.16 -0.0621 0.0853 0.467 0.3309 0.94 0.795 1.11 0.083 0.0831 0.318 0.4982 1.09 0.923 1.28 PRS_PLINK_1.99526231496888e.06 611.1 Abnormal mammogram Both 48 428 11 genitourinary black 428, 48 109, 16 105, 11 107, 4 107, 17 0.0996 0.154 0.517 0.2861 1.1 0.817 1.49 0.0326 0.375 0.931 0.03115 1.03 0.495 2.15 PRS_PLINK_1.99526231496888e.06 611.3 Lump or mass in breast Both 1195 11952 11 genitourinary black 11952, 1195 2998, 294 2979, 294 3041, 288 2932, 318 0.0299 0.0304 0.324 0.4894 1.03 0.971 1.09 0.00489 0.0863 0.955 0.0201 1 0.849 1.19 -0.0378 0.0867 0.663 0.1786 0.963 0.812 1.14 0.102 0.085 0.229 0.6396 1.11 0.938 1.31 PRS_PLINK_1.99526231496888e.06 612 Breast conditions, congenital or relating to hormones Both 675 7059 11 genitourinary black 7059, 675 1764, 178 1772, 158 1757, 167 1765, 172 0.00635 0.0405 0.875 0.05779 1.01 0.93 1.09 -0.126 0.114 0.267 0.5734 0.881 0.705 1.1 -0.0515 0.113 0.647 0.1889 0.95 0.762 1.18 -0.0218 0.112 0.846 0.07266 0.978 0.785 1.22 PRS_PLINK_1.99526231496888e.06 612.2 Hypertrophy of breast (Gynecomastia) Both 644 6692 11 genitourinary black 6692, 644 1673, 176 1680, 153 1666, 151 1672, 164 -0.00668 0.0415 0.872 0.05931 0.993 0.916 1.08 -0.147 0.115 0.204 0.6907 0.864 0.689 1.08 -0.144 0.116 0.213 0.6713 0.866 0.69 1.09 -0.0512 0.114 0.653 0.1849 0.95 0.76 1.19 PRS_PLINK_1.99526231496888e.06 612.3 Congenital anomalies of breast Both 62 597 11 genitourinary black 597, 62 156, 12 146, 15 147, 16 148, 19 0.152 0.131 0.246 0.6085 1.16 0.9 1.5 0.473 0.373 0.205 0.6879 1.61 0.772 3.34 PRS_PLINK_1.99526231496888e.06 613 Other nonmalignant breast conditions Both 1213 13058 11 genitourinary black 13058, 1213 3268, 288 3276, 328 3250, 298 3260, 298 -0.0263 0.0305 0.389 0.4098 0.974 0.918 1.03 0.129 0.0843 0.126 0.8994 1.14 0.964 1.34 0.0416 0.0861 0.629 0.201 1.04 0.881 1.23 0.0387 0.0861 0.653 0.1849 1.04 0.878 1.23 PRS_PLINK_1.99526231496888e.06 613.1 Inflammatory disease of breast Both 519 5681 11 genitourinary black 5681, 519 1429, 119 1420, 148 1410, 125 1420, 127 -0.0362 0.0466 0.437 0.3598 0.964 0.88 1.06 0.223 0.128 0.0819 1.087 1.25 0.972 1.61 0.0619 0.133 0.642 0.1928 1.06 0.82 1.38 0.0766 0.132 0.563 0.2497 1.08 0.833 1.4 PRS_PLINK_1.99526231496888e.06 613.5 Mastodynia Both 52 617 11 genitourinary black 617, 52 155, 13 155, 18 153, 15 154, 6 -0.234 0.156 0.133 0.8751 0.792 0.584 1.07 0.328 0.367 0.372 0.4293 1.39 0.676 2.85 -0.758 0.476 0.111 0.9545 0.469 0.185 1.19 PRS_PLINK_1.99526231496888e.06 613.7 Other signs and symptoms in breast Both 543 5480 11 genitourinary black 5480, 543 1380, 139 1375, 141 1361, 123 1363, 139 0.00911 0.0456 0.842 0.07484 1.01 0.923 1.1 0.0115 0.125 0.927 0.03301 1.01 0.792 1.29 -0.11 0.129 0.395 0.403 0.896 0.696 1.15 0.00969 0.126 0.938 0.02759 1.01 0.79 1.29 PRS_PLINK_1.99526231496888e.06 613.8 Other specified disorders of breast Both 252 2598 11 genitourinary black 2598, 252 653, 61 653, 58 642, 65 649, 68 0.003 0.066 0.964 0.01602 1 0.881 1.14 0.0903 0.185 0.626 0.2037 1.09 0.762 1.57 PRS_PLINK_1.99526231496888e.06 613.9 Breast disorder NOS Both 154 1613 11 genitourinary black 1613, 154 407, 35 401, 42 403, 37 402, 39 PRS_PLINK_1.99526231496888e.06 614 Inflammatory diseases of female pelvic organs Female 4555 46930 11 genitourinary black 46930, 4555 12023, 1166 11513, 1160 11734, 1126 11650, 1102 -0.02 0.0158 0.204 0.6911 0.98 0.95 1.01 0.0386 0.0435 0.374 0.4268 1.04 0.954 1.13 -0.0115 0.0437 0.793 0.1005 0.989 0.907 1.08 -0.0242 0.044 0.583 0.2347 0.976 0.895 1.06 PRS_PLINK_1.99526231496888e.06 614.1 Pelvic peritoneal adhesions, female (postoperative) (postinfection) Female 2029 21054 11 genitourinary black 21054, 2029 5411, 522 5115, 516 5272, 494 5252, 497 -0.029 0.0236 0.22 0.658 0.971 0.927 1.02 0.0456 0.065 0.483 0.3159 1.05 0.921 1.19 -0.0294 0.0656 0.655 0.1839 0.971 0.854 1.1 -0.0183 0.0656 0.78 0.1079 0.982 0.863 1.12 PRS_PLINK_1.99526231496888e.06 614.3 Pelvic inflammatory disease (PID) Female 674 6917 11 genitourinary black 6917, 674 1729, 160 1729, 173 1737, 176 1721, 165 0.00978 0.0406 0.809 0.0918 1.01 0.933 1.09 0.0712 0.114 0.534 0.2727 1.07 0.858 1.34 0.0923 0.114 0.418 0.3791 1.1 0.877 1.37 0.0372 0.116 0.747 0.1264 1.04 0.827 1.3 PRS_PLINK_1.99526231496888e.06 614.31 Acute inflammatory pelvic disease Female 50 511 11 genitourinary black 511, 50 132, 12 124, 13 129, 13 126, 12 -2.14e-05 0.151 1 4.887e-05 1 0.743 1.35 0.232 0.403 0.565 0.2478 1.26 0.572 2.78 0.0572 0.41 0.889 0.05109 1.06 0.474 2.36 -0.012 0.414 0.977 0.01017 0.988 0.439 2.23 PRS_PLINK_1.99526231496888e.06 614.32 Chronic inflammatory pelvic disease Female 335 3472 11 genitourinary black 3472, 335 873, 80 862, 90 870, 88 866, 77 -0.00136 0.0569 0.981 0.008334 0.999 0.893 1.12 0.124 0.16 0.439 0.3572 1.13 0.827 1.55 0.0989 0.161 0.538 0.2691 1.1 0.806 1.51 -0.0269 0.166 0.871 0.06005 0.973 0.704 1.35 PRS_PLINK_1.99526231496888e.06 614.33 Pelvic inflammatory disease, NOS Female 284 2951 11 genitourinary black 2951, 284 749, 70 728, 69 737, 73 737, 72 0.0293 0.0634 0.644 0.1908 1.03 0.909 1.17 -0.000385 0.177 0.998 0.0007561 1 0.707 1.41 0.0531 0.174 0.76 0.1191 1.05 0.75 1.48 0.0343 0.174 0.844 0.07373 1.03 0.735 1.46 PRS_PLINK_1.99526231496888e.06 614.4 Inflammatory diseases of uterus, except cervix Female 219 2266 11 genitourinary black 2266, 219 569, 54 564, 60 566, 49 567, 56 -0.0208 0.072 0.773 0.1119 0.979 0.851 1.13 0.121 0.195 0.536 0.2712 1.13 0.77 1.65 -0.105 0.204 0.608 0.2163 0.9 0.603 1.34 0.0413 0.198 0.835 0.07843 1.04 0.707 1.54 PRS_PLINK_1.99526231496888e.06 614.5 Inflammatory disease of cervix, vagina, and vulva Female 2070 21159 11 genitourinary black 21159, 2070 5302, 508 5278, 540 5298, 527 5275, 494 -0.0147 0.0233 0.528 0.2771 0.985 0.941 1.03 0.0658 0.0648 0.309 0.5096 1.07 0.941 1.21 0.0355 0.0651 0.585 0.2328 1.04 0.912 1.18 -0.0252 0.0661 0.703 0.1528 0.975 0.857 1.11 PRS_PLINK_1.99526231496888e.06 614.51 Cervicitis and endocervicitis Female 1039 10678 11 genitourinary black 10678, 1039 2732, 242 2624, 279 2669, 266 2651, 252 0.00254 0.0325 0.938 0.0279 1 0.941 1.07 0.184 0.0918 0.0446 1.351 1.2 1 1.44 0.117 0.0927 0.207 0.683 1.12 0.937 1.35 0.0715 0.0938 0.446 0.3504 1.07 0.894 1.29 PRS_PLINK_1.99526231496888e.06 614.52 Vaginitis and vulvovaginitis Female 334 3428 11 genitourinary black 3428, 334 863, 81 863, 80 842, 86 856, 86 0.0194 0.0573 0.735 0.1337 1.02 0.911 1.14 -0.0181 0.164 0.912 0.03999 0.982 0.712 1.35 0.0998 0.161 0.536 0.2708 1.1 0.805 1.52 0.0797 0.162 0.622 0.2065 1.08 0.789 1.49 PRS_PLINK_1.99526231496888e.06 614.53 Cyst or abscess of Bartholin's gland Female 632 6251 11 genitourinary black 6251, 632 1610, 163 1534, 177 1557, 147 1550, 145 -0.0441 0.0427 0.302 0.5205 0.957 0.88 1.04 0.131 0.114 0.251 0.6012 1.14 0.912 1.43 -0.0716 0.119 0.546 0.2627 0.931 0.738 1.17 -0.0854 0.119 0.474 0.3239 0.918 0.727 1.16 PRS_PLINK_1.99526231496888e.06 614.54 Abscess or ulceration of vulva Female 205 2238 11 genitourinary black 2238, 205 579, 58 541, 45 560, 56 558, 46 -0.0065 0.0719 0.928 0.03248 0.994 0.863 1.14 -0.187 0.205 0.361 0.442 0.829 0.554 1.24 -0.0226 0.195 0.908 0.04204 0.978 0.667 1.43 -0.181 0.204 0.375 0.4256 0.834 0.559 1.25 PRS_PLINK_1.99526231496888e.06 615 Endometriosis Female 3310 33907 11 genitourinary black 33907, 3310 8680, 853 8311, 846 8533, 815 8378, 796 -0.0114 0.0185 0.539 0.2687 0.989 0.954 1.03 0.0347 0.0509 0.495 0.3052 1.04 0.937 1.14 -0.0282 0.0513 0.583 0.2347 0.972 0.879 1.08 -0.0264 0.0517 0.609 0.2156 0.974 0.88 1.08 PRS_PLINK_1.99526231496888e.06 617 Disorders secondary to childbirth, surgery, trauma Female 222 2413 11 genitourinary black 2413, 222 610, 54 603, 55 600, 49 600, 64 0.0981 0.0672 0.144 0.8407 1.1 0.967 1.26 0.0164 0.198 0.934 0.02958 1.02 0.689 1.5 -0.0778 0.203 0.701 0.1542 0.925 0.622 1.38 0.179 0.191 0.351 0.4552 1.2 0.822 1.74 PRS_PLINK_1.99526231496888e.06 618 Genital prolapse Female 8798 89103 11 genitourinary black 89103, 8798 22347, 2142 22234, 2217 22394, 2217 22105, 2220 0.0138 0.0112 0.218 0.6616 1.01 0.992 1.04 0.0389 0.0317 0.22 0.6574 1.04 0.977 1.11 0.0318 0.0317 0.317 0.4992 1.03 0.97 1.1 0.0449 0.0318 0.158 0.8023 1.05 0.983 1.11 PRS_PLINK_1.99526231496888e.06 618.1 Prolapse of vaginal walls Female 5502 56218 11 genitourinary black 56218, 5502 14078, 1334 14170, 1403 14047, 1363 13908, 1401 0.0214 0.0141 0.129 0.8902 1.02 0.994 1.05 0.0431 0.04 0.282 0.5504 1.04 0.965 1.13 0.0237 0.0403 0.557 0.2543 1.02 0.946 1.11 0.0618 0.0401 0.123 0.9085 1.06 0.983 1.15 PRS_PLINK_1.99526231496888e.06 618.2 Uterine/Uterovaginal prolapse Female 4144 40977 11 genitourinary black 40977, 4144 10265, 1000 10262, 1054 10383, 1073 10055, 1016 0.00556 0.0163 0.733 0.1347 1.01 0.974 1.04 0.0523 0.0463 0.258 0.5881 1.05 0.962 1.15 0.0578 0.0461 0.21 0.678 1.06 0.968 1.16 0.0341 0.0467 0.466 0.3316 1.03 0.944 1.13 PRS_PLINK_1.99526231496888e.06 618.5 Prolapse of vaginal vault after hysterectomy Female 373 3802 11 genitourinary black 3802, 373 958, 91 952, 100 945, 83 947, 98 0.0113 0.0543 0.835 0.07842 1.01 0.909 1.12 0.0975 0.151 0.518 0.2853 1.1 0.82 1.48 -0.077 0.158 0.625 0.204 0.926 0.68 1.26 0.0735 0.152 0.629 0.2017 1.08 0.799 1.45 PRS_PLINK_1.99526231496888e.06 618.6 Vaginal enterocele, congenital or acquired Female 475 5087 11 genitourinary black 5087, 475 1270, 114 1277, 131 1276, 102 1262, 128 0.0169 0.0486 0.729 0.1375 1.02 0.925 1.12 0.149 0.134 0.267 0.5737 1.16 0.893 1.51 -0.102 0.141 0.47 0.3278 0.903 0.684 1.19 0.122 0.134 0.364 0.439 1.13 0.868 1.47 PRS_PLINK_1.99526231496888e.06 619 Noninflammatory female genital disorders Female 6911 70025 11 genitourinary black 70025, 6911 17672, 1764 17469, 1741 17514, 1651 17351, 1755 0.00697 0.0127 0.583 0.2341 1.01 0.982 1.03 -0.00121 0.0354 0.973 0.012 0.999 0.932 1.07 -0.0558 0.0359 0.12 0.921 0.946 0.882 1.01 0.0147 0.0354 0.679 0.1684 1.01 0.947 1.09 PRS_PLINK_1.99526231496888e.06 619.1 Noninflammatory disorders of ovary, fallopian tube, and broad ligament Female 582 5971 11 genitourinary black 5971, 582 1507, 156 1478, 137 1495, 137 1489, 152 -0.0018 0.0435 0.967 0.01461 0.998 0.917 1.09 -0.107 0.122 0.383 0.4169 0.899 0.707 1.14 -0.12 0.122 0.328 0.4845 0.887 0.698 1.13 -0.0132 0.12 0.912 0.03991 0.987 0.781 1.25 PRS_PLINK_1.99526231496888e.06 619.2 Disorders of uterus, NEC Female 2576 26151 11 genitourinary black 26151, 2576 6540, 670 6532, 642 6569, 613 6505, 651 -0.00942 0.0209 0.652 0.1859 0.991 0.951 1.03 -0.0435 0.0579 0.452 0.3447 0.957 0.855 1.07 -0.0919 0.0585 0.117 0.9335 0.912 0.813 1.02 -0.0242 0.0578 0.676 0.1703 0.976 0.872 1.09 PRS_PLINK_1.99526231496888e.06 619.3 Noninflammatory disorders of cervix Female 2316 23245 11 genitourinary black 23245, 2316 5866, 577 5811, 573 5751, 534 5811, 632 0.0331 0.0219 0.13 0.8861 1.03 0.99 1.08 0.00368 0.0618 0.952 0.02117 1 0.889 1.13 -0.0563 0.0628 0.37 0.4321 0.945 0.836 1.07 0.101 0.0605 0.0961 1.017 1.11 0.982 1.25 PRS_PLINK_1.99526231496888e.06 619.4 Noninflammatory disorders of vagina Female 1403 14196 11 genitourinary black 14196, 1403 3551, 318 3564, 374 3555, 361 3523, 349 0.0499 0.0282 0.0769 1.114 1.05 0.995 1.11 0.157 0.0797 0.0487 1.312 1.17 1 1.37 0.127 0.0804 0.115 0.9388 1.14 0.97 1.33 0.103 0.0811 0.202 0.6941 1.11 0.946 1.3 PRS_PLINK_1.99526231496888e.06 619.5 Noninflammatory disorders of vulva and perineum Female 1065 10872 11 genitourinary black 10872, 1065 2713, 281 2720, 269 2725, 252 2709, 263 -0.0233 0.0325 0.474 0.3243 0.977 0.917 1.04 -0.0459 0.0894 0.608 0.2162 0.955 0.802 1.14 -0.112 0.0907 0.218 0.6619 0.894 0.749 1.07 -0.0646 0.0899 0.473 0.3254 0.937 0.786 1.12 PRS_PLINK_1.99526231496888e.06 620 Dysplasia of female genital organs Female 51 574 11 genitourinary black 574, 51 144, 14 144, 10 142, 12 144, 15 0.103 0.139 0.456 0.3412 1.11 0.845 1.46 -0.362 0.409 0.375 0.4257 0.696 0.312 1.55 -0.129 0.396 0.746 0.1275 0.879 0.405 1.91 0.09 0.377 0.811 0.09074 1.09 0.522 2.29 PRS_PLINK_1.99526231496888e.06 621 Endometrial hyperplasia Female 819 8975 11 genitourinary black 8975, 819 2279, 229 2210, 185 2273, 220 2212, 185 -0.0439 0.0372 0.239 0.6222 0.957 0.89 1.03 -0.184 0.103 0.0742 1.129 0.832 0.68 1.02 -0.0377 0.0987 0.703 0.1533 0.963 0.794 1.17 -0.183 0.103 0.0755 1.122 0.833 0.68 1.02 PRS_PLINK_1.99526231496888e.06 622 Polyp of female genital organs Female 8117 82727 11 genitourinary black 82727, 8117 20774, 1985 20670, 2091 20682, 2000 20577, 2038 0.00546 0.0117 0.64 0.1935 1.01 0.983 1.03 0.0565 0.0328 0.0854 1.069 1.06 0.992 1.13 0.0115 0.0332 0.729 0.1375 1.01 0.948 1.08 0.0367 0.0331 0.267 0.5743 1.04 0.972 1.11 PRS_PLINK_1.99526231496888e.06 622.1 Polyp of corpus uteri Female 5988 62113 11 genitourinary black 62113, 5988 15675, 1486 15377, 1528 15573, 1473 15471, 1499 0.00426 0.0136 0.754 0.1226 1 0.978 1.03 0.0469 0.0382 0.219 0.6599 1.05 0.973 1.13 -0.00218 0.0385 0.955 0.02005 0.998 0.925 1.08 0.0234 0.0383 0.541 0.2667 1.02 0.95 1.1 PRS_PLINK_1.99526231496888e.06 622.2 Mucous polyp of cervix Female 2767 26862 11 genitourinary black 26862, 2767 6728, 673 6745, 723 6676, 701 6704, 669 -0.000139 0.0201 0.995 0.002395 1 0.961 1.04 0.0678 0.0562 0.228 0.6419 1.07 0.958 1.19 0.0471 0.0566 0.406 0.3918 1.05 0.938 1.17 -0.00239 0.0572 0.967 0.01472 0.998 0.892 1.12 PRS_PLINK_1.99526231496888e.06 623 Hypertrophy of female genital organs Female 1009 10437 11 genitourinary black 10437, 1009 2622, 263 2622, 237 2619, 230 2574, 279 0.0153 0.0328 0.642 0.1927 1.02 0.952 1.08 -0.1 0.0935 0.284 0.5471 0.905 0.753 1.09 -0.131 0.0942 0.163 0.787 0.877 0.729 1.05 0.0749 0.0903 0.407 0.3904 1.08 0.903 1.29 PRS_PLINK_1.99526231496888e.06 624 Symptoms involving female genital tract Female 582 6032 11 genitourinary black 6032, 582 1514, 166 1509, 130 1517, 148 1492, 138 -0.0407 0.0438 0.353 0.4523 0.96 0.881 1.05 -0.241 0.122 0.0486 1.314 0.786 0.619 0.998 -0.114 0.118 0.336 0.4731 0.892 0.708 1.13 -0.161 0.121 0.183 0.7374 0.852 0.672 1.08 PRS_PLINK_1.99526231496888e.06 624.1 Dystrophy of female genital tract Female 171 1815 11 genitourinary black 1815, 171 461, 51 448, 39 458, 38 448, 43 -0.0168 0.0795 0.832 0.07972 0.983 0.842 1.15 -0.192 0.222 0.387 0.4122 0.825 0.534 1.27 -0.267 0.223 0.231 0.6373 0.766 0.495 1.18 -0.113 0.216 0.6 0.222 0.893 0.585 1.36 PRS_PLINK_1.99526231496888e.06 624.2 Atrophy of female genital tract Female 320 3333 11 genitourinary black 3333, 320 845, 95 826, 62 829, 88 833, 75 -0.0414 0.0602 0.491 0.3087 0.959 0.853 1.08 -0.408 0.169 0.0159 1.798 0.665 0.478 0.927 -0.0449 0.155 0.772 0.1122 0.956 0.706 1.3 -0.222 0.161 0.167 0.7773 0.801 0.584 1.1 PRS_PLINK_1.99526231496888e.06 624.9 stress incontinence, female Female 4407 45979 11 genitourinary black 45979, 4407 11591, 1108 11440, 1129 11483, 1022 11452, 1146 0.00659 0.0159 0.678 0.1688 1.01 0.976 1.04 0.0326 0.0443 0.462 0.3354 1.03 0.947 1.13 -0.0685 0.0453 0.131 0.8843 0.934 0.854 1.02 0.0499 0.0442 0.259 0.5866 1.05 0.964 1.15 PRS_PLINK_1.99526231496888e.06 625 Pain and other symptoms associated with female genital organs Female 2427 24139 11 genitourinary black 24139, 2427 6172, 604 5949, 599 5999, 605 6014, 619 0.0133 0.0216 0.539 0.2684 1.01 0.971 1.06 0.0291 0.0604 0.63 0.2008 1.03 0.915 1.16 0.0282 0.0603 0.64 0.1937 1.03 0.914 1.16 0.0521 0.06 0.385 0.4146 1.05 0.937 1.18 PRS_PLINK_1.99526231496888e.06 625.1 Dyspareunia Female 990 9975 11 genitourinary black 9975, 990 2504, 237 2502, 259 2502, 236 2467, 258 0.036 0.0339 0.288 0.5406 1.04 0.97 1.11 0.0886 0.0941 0.346 0.4604 1.09 0.909 1.31 -0.00375 0.096 0.969 0.01373 0.996 0.825 1.2 0.104 0.0941 0.271 0.5666 1.11 0.922 1.33 PRS_PLINK_1.99526231496888e.06 626 Disorders of menstruation and other abnormal bleeding from female genital tract Female 13511 95319 11 genitourinary black 95319, 13511 24473, 3410 23179, 3393 23951, 3312 23696, 3391 0.0101 0.00937 0.28 0.5529 1.01 0.992 1.03 0.0536 0.0261 0.04 1.398 1.06 1 1.11 0.00327 0.0262 0.901 0.04538 1 0.953 1.06 0.0512 0.0261 0.0497 1.304 1.05 1 1.11 PRS_PLINK_1.99526231496888e.06 626.1 Irregular menstrual cycle/bleeding Female 11804 91590 11 genitourinary black 91590, 11804 23564, 2990 22247, 2935 23122, 2879 22638, 2996 0.0137 0.00992 0.167 0.7762 1.01 0.994 1.03 0.0414 0.0277 0.135 0.8698 1.04 0.987 1.1 -0.0113 0.0278 0.684 0.165 0.989 0.936 1.04 0.0579 0.0276 0.0356 1.448 1.06 1 1.12 PRS_PLINK_1.99526231496888e.06 626.11 Absent or infrequent menstruation Female 86 937 11 genitourinary black 937, 86 236, 26 234, 19 234, 22 233, 19 -0.0778 0.117 0.505 0.2971 0.925 0.736 1.16 -0.316 0.308 0.305 0.5156 0.729 0.399 1.33 -0.153 0.298 0.608 0.2159 0.859 0.479 1.54 -0.287 0.307 0.351 0.4546 0.751 0.411 1.37 PRS_PLINK_1.99526231496888e.06 626.12 Excessive or frequent menstruation Female 8024 77074 11 genitourinary black 77074, 8024 19287, 1942 19308, 2078 19409, 1911 19052, 2090 0.0203 0.0118 0.0854 1.068 1.02 0.997 1.04 0.0668 0.0332 0.044 1.357 1.07 1 1.14 -0.0206 0.0338 0.541 0.2666 0.98 0.917 1.05 0.0925 0.0332 0.00528 2.277 1.1 1.03 1.17 PRS_PLINK_1.99526231496888e.06 626.13 Irregular menstrual cycle Female 1612 16218 11 genitourinary black 16218, 1612 4164, 411 3943, 398 4107, 406 4001, 397 0.000221 0.0264 0.993 0.002915 1 0.95 1.05 0.0224 0.0736 0.761 0.1188 1.02 0.885 1.18 0.000703 0.0733 0.992 0.003337 1 0.867 1.16 0.0055 0.0738 0.941 0.02659 1.01 0.87 1.16 PRS_PLINK_1.99526231496888e.06 626.14 Irregular menstrual bleeding Female 3186 32196 11 genitourinary black 32196, 3186 8224, 811 7884, 760 8089, 803 7993, 810 0.0118 0.0188 0.529 0.2766 1.01 0.975 1.05 -0.0225 0.0528 0.671 0.1735 0.978 0.882 1.08 0.00554 0.0522 0.915 0.03837 1.01 0.908 1.11 0.0255 0.0521 0.624 0.2048 1.03 0.926 1.14 PRS_PLINK_1.99526231496888e.06 626.2 Dysmenorrhea Female 1464 15245 11 genitourinary black 15245, 1464 3874, 372 3752, 396 3815, 338 3802, 358 -0.0258 0.0279 0.356 0.4487 0.975 0.923 1.03 0.0963 0.0757 0.203 0.6925 1.1 0.949 1.28 -0.0804 0.0784 0.306 0.5149 0.923 0.791 1.08 -0.0136 0.0775 0.86 0.0653 0.986 0.847 1.15 PRS_PLINK_1.99526231496888e.06 626.4 Premenstrual tension syndromes Female 119 1378 11 genitourinary black 1378, 119 361, 26 328, 22 347, 34 342, 37 0.183 0.0896 0.0413 1.384 1.2 1.01 1.43 -0.0939 0.294 0.75 0.1252 0.91 0.511 1.62 0.287 0.265 0.28 0.5535 1.33 0.792 2.24 0.402 0.262 0.124 0.9065 1.5 0.896 2.5 PRS_PLINK_1.99526231496888e.06 626.8 Infertility, female Female 1228 12044 11 genitourinary black 12044, 1228 3063, 313 3003, 327 2977, 281 3000, 305 -0.0161 0.0306 0.6 0.2216 0.984 0.927 1.04 0.0631 0.0831 0.447 0.3493 1.07 0.905 1.25 -0.0798 0.086 0.354 0.4515 0.923 0.78 1.09 -0.0043 0.0843 0.959 0.01804 0.996 0.844 1.17 PRS_PLINK_1.99526231496888e.06 627 Menopausal and postmenopausal disorders Female 7565 79145 11 genitourinary black 79145, 7565 19856, 1864 19722, 1869 19843, 1926 19701, 1906 0.0158 0.012 0.187 0.7282 1.02 0.992 1.04 0.00856 0.0342 0.803 0.09551 1.01 0.943 1.08 0.0333 0.034 0.328 0.4842 1.03 0.967 1.11 0.028 0.0341 0.411 0.3861 1.03 0.962 1.1 PRS_PLINK_1.99526231496888e.06 627.1 Postmenopausal bleeding Female 6532 68560 11 genitourinary black 68560, 6532 17142, 1619 17263, 1625 17278, 1680 16856, 1608 0.0105 0.0129 0.415 0.382 1.01 0.985 1.04 -0.00461 0.0367 0.9 0.04571 0.995 0.926 1.07 0.0294 0.0365 0.421 0.376 1.03 0.959 1.11 0.00824 0.0369 0.823 0.08449 1.01 0.938 1.08 PRS_PLINK_1.99526231496888e.06 627.2 Symptomatic menopause Female 136 1443 11 genitourinary black 1443, 136 361, 29 365, 29 361, 38 356, 40 0.151 0.0851 0.077 1.113 1.16 0.984 1.37 -0.00853 0.267 0.975 0.0112 0.992 0.587 1.67 0.259 0.253 0.305 0.5153 1.3 0.789 2.13 0.352 0.251 0.161 0.7939 1.42 0.869 2.33 PRS_PLINK_1.99526231496888e.06 627.3 Postmenopausal atrophic vaginitis Female 797 8226 11 genitourinary black 8226, 797 2084, 190 2041, 193 2053, 200 2046, 214 0.0232 0.0372 0.533 0.2734 1.02 0.952 1.1 0.0339 0.106 0.751 0.1246 1.03 0.84 1.27 0.0736 0.106 0.486 0.3131 1.08 0.875 1.32 0.137 0.104 0.188 0.7269 1.15 0.935 1.41 PRS_PLINK_1.99526231496888e.06 627.4 Premenopausal menorrhagia Female 241 2526 11 genitourinary black 2526, 241 648, 52 619, 58 627, 68 631, 63 0.081 0.0667 0.224 0.649 1.08 0.952 1.24 0.147 0.197 0.456 0.3411 1.16 0.787 1.7 0.283 0.191 0.138 0.8615 1.33 0.913 1.93 0.227 0.194 0.242 0.6168 1.25 0.858 1.83 PRS_PLINK_1.99526231496888e.06 628 Ovarian cyst Female 3823 39143 11 genitourinary black 39143, 3823 9998, 980 9690, 978 9678, 910 9771, 954 -0.00772 0.0171 0.653 0.1853 0.992 0.96 1.03 0.0295 0.0474 0.534 0.2729 1.03 0.939 1.13 -0.0412 0.0482 0.392 0.4062 0.96 0.873 1.05 -0.00246 0.0477 0.959 0.01829 0.998 0.909 1.1 PRS_PLINK_1.99526231496888e.06 634 Miscarriage; stillbirth Female 4734 32491 12 pregnancy complications royalblue4 32491, 4734 8225, 1278 8093, 1134 8050, 1165 8115, 1154 -0.0154 0.0161 0.34 0.468 0.985 0.954 1.02 -0.105 0.044 0.0177 1.753 0.901 0.826 0.982 -0.0684 0.0438 0.118 0.9265 0.934 0.857 1.02 -0.0769 0.0439 0.0796 1.099 0.926 0.85 1.01 PRS_PLINK_1.99526231496888e.06 634.1 Missed abortion/Hydatidiform mole Female 1022 10166 12 pregnancy complications royalblue4 10166, 1022 2540, 262 2540, 229 2541, 259 2541, 270 0.0192 0.0334 0.566 0.247 1.02 0.955 1.09 -0.133 0.0945 0.16 0.7961 0.876 0.728 1.05 -0.012 0.0918 0.896 0.0475 0.988 0.825 1.18 0.0272 0.091 0.765 0.1164 1.03 0.86 1.23 PRS_PLINK_1.99526231496888e.06 634.3 Ectopic pregnancy Female 301 2930 12 pregnancy complications royalblue4 2930, 301 741, 83 734, 67 730, 69 724, 81 0.00199 0.0613 0.974 0.01139 1 0.889 1.13 -0.209 0.171 0.223 0.6515 0.812 0.58 1.14 -0.168 0.17 0.322 0.4926 0.845 0.606 1.18 0.00485 0.164 0.976 0.01038 1 0.729 1.39 PRS_PLINK_1.99526231496888e.06 635 Hemorrhage during pregnancy; childbirth and postpartum Female 1817 15648 12 pregnancy complications royalblue4 15648, 1817 4001, 487 3849, 433 3886, 443 3905, 453 0.0038 0.0256 0.882 0.05453 1 0.955 1.06 -0.0776 0.0698 0.266 0.5746 0.925 0.807 1.06 -0.0616 0.0695 0.375 0.4258 0.94 0.82 1.08 -0.0404 0.0692 0.559 0.2527 0.96 0.839 1.1 PRS_PLINK_1.99526231496888e.06 635.2 Antepartum hemorrhage, abruptio placentae, and placenta previa Female 798 7773 12 pregnancy complications royalblue4 7773, 798 2003, 214 1910, 202 1920, 182 1935, 200 0.0032 0.0386 0.934 0.02966 1 0.93 1.08 -0.00139 0.103 0.989 0.004703 0.999 0.816 1.22 -0.122 0.106 0.249 0.6035 0.885 0.72 1.09 -0.0254 0.103 0.805 0.09394 0.975 0.796 1.19 PRS_PLINK_1.99526231496888e.06 635.3 Placenta previa and abruptio placenta Female 1167 11078 12 pregnancy complications royalblue4 11078, 1167 2786, 310 2755, 270 2774, 299 2761, 287 -0.00142 0.0316 0.964 0.01582 0.999 0.939 1.06 -0.127 0.0873 0.146 0.8358 0.881 0.742 1.05 -0.0305 0.0852 0.721 0.1423 0.97 0.821 1.15 -0.0587 0.0861 0.496 0.3046 0.943 0.797 1.12 PRS_PLINK_1.99526231496888e.06 636 Early or threatened labor; hemorrhage in early pregnancy Female 2145 17938 12 pregnancy complications royalblue4 17938, 2145 4564, 563 4409, 509 4477, 512 4485, 559 0.0132 0.0235 0.575 0.2405 1.01 0.968 1.06 -0.063 0.0648 0.331 0.4805 0.939 0.827 1.07 -0.0765 0.0646 0.237 0.6257 0.926 0.816 1.05 0.014 0.0634 0.825 0.0837 1.01 0.896 1.15 PRS_PLINK_1.99526231496888e.06 636.2 Early onset of delivery Female 563 5515 12 pregnancy complications royalblue4 5515, 563 1380, 155 1385, 128 1383, 130 1364, 149 -0.00355 0.0453 0.938 0.02802 0.996 0.912 1.09 -0.192 0.125 0.124 0.9067 0.825 0.646 1.05 -0.179 0.124 0.15 0.8233 0.836 0.655 1.07 -0.0313 0.121 0.795 0.09948 0.969 0.765 1.23 PRS_PLINK_1.99526231496888e.06 636.3 Hemorrhage in early pregnancy Female 985 9563 12 pregnancy complications royalblue4 9563, 985 2436, 257 2359, 234 2374, 239 2391, 255 0.0148 0.0342 0.665 0.1773 1.01 0.949 1.09 -0.0596 0.0946 0.528 0.277 0.942 0.783 1.13 -0.0485 0.0941 0.606 0.2175 0.953 0.792 1.15 0.0144 0.0928 0.877 0.05714 1.01 0.846 1.22 PRS_PLINK_1.99526231496888e.06 638 Other high-risk pregnancy Female 61 625 12 pregnancy complications royalblue4 625, 61 160, 15 156, 16 153, 17 156, 13 -0.0334 0.146 0.819 0.08677 0.967 0.726 1.29 0.0456 0.365 0.901 0.04548 1.05 0.512 2.14 0.138 0.363 0.704 0.1524 1.15 0.564 2.34 -0.114 0.382 0.765 0.1164 0.892 0.422 1.89 PRS_PLINK_1.99526231496888e.06 642 Hypertension complicating pregnancy, childbirth, and the puerperium Female 981 10029 12 pregnancy complications royalblue4 10029, 981 2522, 260 2520, 261 2476, 223 2507, 237 -0.0276 0.0348 0.427 0.3698 0.973 0.909 1.04 0.00365 0.0919 0.968 0.01399 1 0.838 1.2 -0.137 0.0953 0.149 0.8257 0.872 0.723 1.05 -0.0856 0.0939 0.362 0.441 0.918 0.764 1.1 PRS_PLINK_1.99526231496888e.06 642.1 Preeclampsia and eclampsia Female 271 2751 12 pregnancy complications royalblue4 2751, 271 711, 60 670, 71 685, 67 684, 73 0.0838 0.064 0.19 0.7206 1.09 0.959 1.23 0.227 0.182 0.212 0.6728 1.25 0.878 1.79 0.141 0.184 0.442 0.3543 1.15 0.803 1.65 0.241 0.181 0.183 0.7373 1.27 0.893 1.81 PRS_PLINK_1.99526231496888e.06 643 Excessive vomiting in pregnancy Female 185 1948 12 pregnancy complications royalblue4 1948, 185 496, 56 477, 52 489, 46 484, 31 -0.22 0.0838 0.00863 2.064 0.802 0.681 0.946 -0.0337 0.201 0.867 0.0621 0.967 0.652 1.43 -0.177 0.207 0.394 0.4048 0.838 0.558 1.26 -0.546 0.229 0.0172 1.766 0.579 0.37 0.908 PRS_PLINK_1.99526231496888e.06 643.1 Hyperemesis gravidarum Female 131 1363 12 pregnancy complications royalblue4 1363, 131 341, 38 341, 38 344, 29 337, 26 -0.155 0.0975 0.113 0.9486 0.857 0.708 1.04 -0.000686 0.239 0.998 0.000997 0.999 0.626 1.6 -0.27 0.254 0.288 0.5403 0.764 0.464 1.26 -0.347 0.261 0.183 0.7378 0.707 0.424 1.18 PRS_PLINK_1.99526231496888e.06 645 Late pregnancy and failed induction Female 1147 11281 12 pregnancy complications royalblue4 11281, 1147 2908, 300 2758, 283 2807, 282 2804, 282 0.000477 0.0317 0.988 0.005248 1 0.94 1.06 -0.00355 0.0869 0.967 0.01439 0.996 0.84 1.18 -0.0249 0.0869 0.774 0.111 0.975 0.823 1.16 -0.0266 0.0869 0.76 0.1192 0.974 0.821 1.15 PRS_PLINK_1.99526231496888e.06 646 Other complications of pregnancy NEC Female 2016 18854 12 pregnancy complications royalblue4 18854, 2016 4839, 531 4595, 489 4764, 486 4651, 508 -0.00423 0.0241 0.861 0.06522 0.996 0.95 1.04 -0.0315 0.0659 0.633 0.1988 0.969 0.851 1.1 -0.0736 0.066 0.264 0.5782 0.929 0.816 1.06 0.00019 0.0653 0.998 0.001009 1 0.88 1.14 PRS_PLINK_1.99526231496888e.06 647 Infectious and parasitic complications affecting pregnancy Female 59 600 12 pregnancy complications royalblue4 600, 59 150, 19 151, 18 150, 6 149, 16 0.00637 0.132 0.962 0.01699 1.01 0.776 1.3 -0.0632 0.339 0.852 0.06955 0.939 0.483 1.82 -1.1 0.459 0.0169 1.772 0.334 0.136 0.821 -0.182 0.355 0.608 0.2159 0.834 0.416 1.67 PRS_PLINK_1.99526231496888e.06 647.1 Infections of genitourinary tract during pregnancy Female 258 2476 12 pregnancy complications royalblue4 2476, 258 634, 57 607, 61 622, 68 613, 72 0.0997 0.0646 0.122 0.9125 1.1 0.974 1.25 0.122 0.191 0.522 0.2822 1.13 0.777 1.64 0.205 0.187 0.272 0.5653 1.23 0.851 1.77 0.25 0.185 0.176 0.7548 1.28 0.894 1.85 PRS_PLINK_1.99526231496888e.06 649 Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium Female 103 1010 12 pregnancy complications royalblue4 1010, 103 260, 32 245, 23 253, 26 252, 22 -0.0652 0.105 0.536 0.2712 0.937 0.762 1.15 -0.254 0.284 0.371 0.4301 0.776 0.445 1.35 -0.173 0.273 0.526 0.2791 0.841 0.492 1.44 -0.344 0.288 0.233 0.6331 0.709 0.403 1.25 PRS_PLINK_1.99526231496888e.06 649.1 Diabetes or abnormal glucose tolerance complicating pregnancy Female 176 1744 12 pregnancy complications royalblue4 1744, 176 452, 46 420, 45 442, 42 429, 43 -0.00871 0.0825 0.916 0.03815 0.991 0.843 1.17 0.0546 0.217 0.802 0.09605 1.06 0.69 1.62 -0.0546 0.221 0.805 0.09422 0.947 0.614 1.46 -0.00888 0.22 0.968 0.01418 0.991 0.643 1.53 PRS_PLINK_1.99526231496888e.06 650 Normal delivery Female 1772 17119 12 pregnancy complications royalblue4 17119, 1772 4411, 438 4195, 428 4293, 460 4215, 444 0.0174 0.0255 0.496 0.3042 1.02 0.968 1.07 0.0296 0.0713 0.678 0.1686 1.03 0.896 1.18 0.0764 0.07 0.275 0.5605 1.08 0.941 1.24 0.0627 0.0707 0.375 0.4257 1.06 0.927 1.22 PRS_PLINK_1.99526231496888e.06 651 Multiple gestation Female 310 3126 12 pregnancy complications royalblue4 3126, 310 785, 79 789, 86 770, 64 781, 81 -0.0293 0.0614 0.633 0.1983 0.971 0.861 1.1 0.0628 0.163 0.7 0.1551 1.06 0.774 1.47 -0.194 0.174 0.265 0.5763 0.823 0.585 1.16 0.0256 0.165 0.876 0.05728 1.03 0.743 1.42 PRS_PLINK_1.99526231496888e.06 652 Malposition and malpresentation of fetus or obstruction Female 1590 14954 12 pregnancy complications royalblue4 14954, 1590 3853, 422 3643, 392 3728, 389 3726, 386 -0.0244 0.0273 0.371 0.4301 0.976 0.925 1.03 -0.0158 0.0738 0.83 0.08095 0.984 0.852 1.14 -0.0485 0.0739 0.512 0.2909 0.953 0.824 1.1 -0.0518 0.074 0.484 0.3152 0.95 0.821 1.1 PRS_PLINK_1.99526231496888e.06 653 Problems associated with amniotic cavity and membranes Female 1281 12312 12 pregnancy complications royalblue4 12312, 1281 3161, 327 3001, 313 3078, 322 3067, 318 -0.00119 0.0303 0.969 0.01385 0.999 0.941 1.06 0.0094 0.083 0.91 0.04104 1.01 0.858 1.19 0.00861 0.0824 0.917 0.03771 1.01 0.858 1.19 0.00377 0.0826 0.964 0.0161 1 0.854 1.18 PRS_PLINK_1.99526231496888e.06 654 Other and unspecified complications of birth; puerperium affecting management of mother Female 66 656 12 pregnancy complications royalblue4 656, 66 170, 13 158, 17 168, 7 160, 29 0.328 0.128 0.0106 1.974 1.39 1.08 1.78 0.268 0.37 0.47 0.3283 1.31 0.633 2.7 -0.552 0.449 0.22 0.6585 0.576 0.239 1.39 0.838 0.343 0.0146 1.837 2.31 1.18 4.53 PRS_PLINK_1.99526231496888e.06 655 Known or suspected fetal abnormality affecting management of mother Female 3940 26537 12 pregnancy complications royalblue4 26537, 3940 6784, 1056 6502, 957 6618, 972 6624, 954 -0.0271 0.0178 0.128 0.8941 0.973 0.94 1.01 -0.0606 0.0484 0.21 0.6777 0.941 0.856 1.03 -0.0624 0.0482 0.195 0.7101 0.939 0.855 1.03 -0.0698 0.0484 0.149 0.8275 0.933 0.848 1.03 PRS_PLINK_1.99526231496888e.06 656 Other perinatal conditions of fetus or newborn Both 95 977 12 pregnancy complications royalblue4 977, 95 254, 25 234, 20 244, 25 244, 25 0.0598 0.105 0.569 0.2446 1.06 0.864 1.3 -0.125 0.306 0.683 0.1655 0.883 0.485 1.61 0.0543 0.289 0.851 0.07014 1.06 0.599 1.86 0.0413 0.289 0.886 0.05237 1.04 0.591 1.84 PRS_PLINK_1.99526231496888e.06 661 Fetal distress and abnormal forces of labor Female 2086 16594 12 pregnancy complications royalblue4 16594, 2086 4205, 551 4106, 544 4148, 517 4127, 473 -0.053 0.0244 0.0299 1.524 0.948 0.904 0.995 0.0194 0.0645 0.763 0.1172 1.02 0.898 1.16 -0.0485 0.0653 0.457 0.3396 0.953 0.838 1.08 -0.122 0.0666 0.0676 1.17 0.885 0.777 1.01 PRS_PLINK_1.99526231496888e.06 663 Umbilical cord complications during labor and delivery Female 492 4803 12 pregnancy complications royalblue4 4803, 492 1237, 126 1169, 122 1205, 128 1189, 116 -0.0343 0.0493 0.487 0.3125 0.966 0.877 1.06 0.0218 0.133 0.87 0.06066 1.02 0.788 1.33 0.0452 0.131 0.731 0.1364 1.05 0.809 1.35 -0.0425 0.134 0.752 0.124 0.958 0.737 1.25 PRS_PLINK_1.99526231496888e.06 665 Obstetrical/birth trauma Female 4864 26481 12 pregnancy complications royalblue4 26481, 4864 6744, 1286 6494, 1193 6652, 1206 6580, 1176 -0.0206 0.0164 0.209 0.6796 0.98 0.949 1.01 -0.0336 0.0446 0.452 0.3449 0.967 0.886 1.06 -0.048 0.0446 0.281 0.5507 0.953 0.873 1.04 -0.0514 0.0448 0.252 0.5989 0.95 0.87 1.04 PRS_PLINK_1.99526231496888e.06 669 Complications of labor and delivery NEC Female 2333 19087 12 pregnancy complications royalblue4 19087, 2333 4860, 609 4693, 556 4824, 574 4703, 593 0.000334 0.0226 0.988 0.005145 1 0.957 1.05 -0.0585 0.0623 0.348 0.4587 0.943 0.835 1.07 -0.0547 0.0618 0.376 0.425 0.947 0.839 1.07 0.00817 0.0614 0.894 0.0486 1.01 0.894 1.14 PRS_PLINK_1.99526231496888e.06 671 Venous/cerebrovascular complications embolism in pregnancy and the puerperium Female 146 1472 12 pregnancy complications royalblue4 1472, 146 378, 52 357, 31 370, 33 366, 30 -0.19 0.097 0.0496 1.304 0.827 0.684 1 -0.46 0.236 0.0508 1.294 0.631 0.398 1 -0.428 0.233 0.0656 1.183 0.652 0.413 1.03 -0.507 0.238 0.0333 1.478 0.603 0.378 0.961 PRS_PLINK_1.99526231496888e.06 674 Other complications of the puerperium NEC Female 241 2368 12 pregnancy complications royalblue4 2368, 241 602, 66 581, 53 593, 63 591, 59 -0.0144 0.0683 0.833 0.07927 0.986 0.862 1.13 -0.197 0.192 0.305 0.5154 0.821 0.564 1.2 -0.0445 0.184 0.809 0.09204 0.957 0.667 1.37 -0.0943 0.187 0.614 0.212 0.91 0.631 1.31 PRS_PLINK_1.99526231496888e.06 676 Other disorders of the breast associated with childbirth and disorders of lactation Female 58 565 12 pregnancy complications royalblue4 565, 58 147, 10 138, 19 139, 18 141, 11 -0.0111 0.143 0.938 0.02776 0.989 0.748 1.31 0.669 0.392 0.088 1.055 1.95 0.905 4.21 0.65 0.394 0.0991 1.004 1.92 0.885 4.15 0.136 0.429 0.751 0.1243 1.15 0.494 2.66 PRS_PLINK_1.99526231496888e.06 679 Complications of in utero procedures Female 48 490 13 dermatologic firebrick 490, 48 123, 10 122, 8 125, 17 120, 13 0.144 0.152 0.342 0.4654 1.16 0.858 1.56 -0.236 0.459 0.607 0.2169 0.79 0.321 1.94 0.489 0.398 0.219 0.6596 1.63 0.748 3.56 0.252 0.417 0.545 0.2632 1.29 0.568 2.91 PRS_PLINK_1.99526231496888e.06 681 Superficial cellulitis and abscess Both 4027 51507 13 dermatologic firebrick 51507, 4027 12892, 958 12962, 987 12771, 1001 12868, 1079 0.041 0.0161 0.011 1.96 1.04 1.01 1.08 0.0264 0.047 0.574 0.2409 1.03 0.936 1.13 0.0589 0.0469 0.209 0.679 1.06 0.967 1.16 0.129 0.0462 0.00532 2.274 1.14 1.04 1.24 PRS_PLINK_1.99526231496888e.06 681.1 Cellulitis and abscess of fingers/toes Both 353 4109 13 dermatologic firebrick 4109, 353 1029, 92 1029, 98 1022, 81 1027, 82 -0.0674 0.056 0.229 0.6402 0.935 0.838 1.04 0.062 0.151 0.681 0.1668 1.06 0.792 1.43 -0.107 0.158 0.496 0.3047 0.898 0.66 1.22 -0.0989 0.157 0.529 0.2762 0.906 0.666 1.23 PRS_PLINK_1.99526231496888e.06 681.2 Cellulitis and abscess of face/neck Both 346 3838 13 dermatologic firebrick 3838, 346 958, 86 960, 81 967, 101 951, 78 0.000522 0.0561 0.993 0.003232 1 0.896 1.12 -0.0651 0.16 0.685 0.1645 0.937 0.684 1.28 0.166 0.153 0.278 0.556 1.18 0.875 1.59 -0.0703 0.162 0.664 0.1776 0.932 0.679 1.28 PRS_PLINK_1.99526231496888e.06 681.3 Cellulitis and abscess of arm/hand Both 2928 38974 13 dermatologic firebrick 38974, 2928 9733, 696 9838, 719 9673, 719 9719, 792 0.0423 0.0189 0.0251 1.601 1.04 1.01 1.08 0.0241 0.055 0.661 0.1797 1.02 0.92 1.14 0.0444 0.0551 0.42 0.3771 1.05 0.938 1.16 0.138 0.0539 0.0106 1.974 1.15 1.03 1.28 PRS_PLINK_1.99526231496888e.06 681.5 Cellulitis and abscess of leg, except foot Both 2932 39017 13 dermatologic firebrick 39017, 2932 9766, 698 9781, 715 9714, 718 9745, 799 0.0455 0.0188 0.0156 1.806 1.05 1.01 1.09 0.0242 0.0551 0.66 0.1807 1.02 0.92 1.14 0.039 0.055 0.479 0.3201 1.04 0.933 1.16 0.144 0.0538 0.00733 2.135 1.16 1.04 1.28 PRS_PLINK_1.99526231496888e.06 681.6 Cellulitis and abscess of foot, toe Both 2904 38675 13 dermatologic firebrick 38675, 2904 9693, 691 9678, 709 9660, 723 9633, 779 0.0433 0.0189 0.022 1.657 1.04 1.01 1.08 0.0287 0.0553 0.603 0.2193 1.03 0.923 1.15 0.0541 0.0551 0.326 0.4871 1.06 0.948 1.18 0.133 0.0542 0.0141 1.852 1.14 1.03 1.27 PRS_PLINK_1.99526231496888e.06 681.7 Cellulitis and abscess of trunk Both 358 4375 13 dermatologic firebrick 4375, 358 1102, 66 1091, 96 1099, 85 1083, 111 0.172 0.0525 0.00105 2.98 1.19 1.07 1.32 0.385 0.164 0.0188 1.725 1.47 1.07 2.03 0.265 0.168 0.115 0.9403 1.3 0.938 1.81 0.545 0.16 0.000675 3.17 1.72 1.26 2.36 PRS_PLINK_1.99526231496888e.06 686 Other local infections of skin and subcutaneous tissue Both 807 9636 13 dermatologic firebrick 9636, 807 2425, 185 2403, 165 2395, 222 2408, 234 0.121 0.0355 0.000655 3.184 1.13 1.05 1.21 -0.11 0.111 0.32 0.4948 0.896 0.721 1.11 0.191 0.103 0.064 1.194 1.21 0.989 1.48 0.245 0.102 0.0169 1.773 1.28 1.04 1.56 PRS_PLINK_1.99526231496888e.06 686.1 Carbuncle and furuncle Both 1475 17138 13 dermatologic firebrick 17138, 1475 4293, 326 4281, 377 4274, 391 4282, 381 0.0553 0.0269 0.0398 1.4 1.06 1 1.11 0.149 0.0785 0.058 1.237 1.16 0.995 1.35 0.187 0.078 0.0164 1.785 1.21 1.03 1.4 0.174 0.0785 0.0268 1.572 1.19 1.02 1.39 PRS_PLINK_1.99526231496888e.06 686.3 Pilonidal cyst Both 404 4550 13 dermatologic firebrick 4550, 404 1136, 104 1145, 102 1130, 94 1136, 104 0.00184 0.0515 0.971 0.01258 1 0.906 1.11 -0.0167 0.145 0.908 0.04194 0.983 0.741 1.31 -0.102 0.147 0.488 0.312 0.903 0.676 1.21 0.00349 0.144 0.981 0.008459 1 0.756 1.33 PRS_PLINK_1.99526231496888e.06 686.4 Pyogenic granuloma Both 255 2627 13 dermatologic firebrick 2627, 255 661, 77 654, 67 657, 64 653, 47 -0.144 0.0677 0.0329 1.483 0.865 0.758 0.988 -0.142 0.175 0.417 0.38 0.868 0.616 1.22 -0.193 0.177 0.274 0.5615 0.824 0.583 1.17 -0.486 0.191 0.0111 1.954 0.615 0.423 0.895 PRS_PLINK_1.99526231496888e.06 687 Symptoms affecting skin Both 351 3979 13 dermatologic firebrick 3979, 351 1005, 73 997, 71 994, 98 981, 109 0.165 0.0541 0.00229 2.64 1.18 1.06 1.31 -0.0188 0.171 0.912 0.03979 0.981 0.702 1.37 0.3 0.16 0.0601 1.221 1.35 0.987 1.85 0.429 0.157 0.00619 2.208 1.54 1.13 2.09 PRS_PLINK_1.99526231496888e.06 687.1 Rash and other nonspecific skin eruption Both 1288 15623 13 dermatologic firebrick 15623, 1288 3918, 308 3893, 293 3918, 362 3893, 325 0.038 0.0286 0.184 0.7351 1.04 0.982 1.1 -0.0448 0.0845 0.596 0.2249 0.956 0.81 1.13 0.164 0.0806 0.0423 1.374 1.18 1.01 1.38 0.0599 0.0825 0.468 0.3301 1.06 0.903 1.25 PRS_PLINK_1.99526231496888e.06 687.2 Localized superficial swelling, mass, or lump Both 195 2039 13 dermatologic firebrick 2039, 195 530, 43 491, 43 508, 47 510, 62 0.186 0.0729 0.0109 1.962 1.2 1.04 1.39 0.0646 0.221 0.77 0.1133 1.07 0.692 1.65 0.142 0.217 0.511 0.2918 1.15 0.754 1.76 0.395 0.206 0.0545 1.264 1.48 0.992 2.22 PRS_PLINK_1.99526231496888e.06 687.3 Changes in skin texture Both 71 794 13 dermatologic firebrick 794, 71 203, 15 192, 14 201, 19 196, 23 0.147 0.121 0.225 0.6487 1.16 0.914 1.47 -0.0498 0.372 0.894 0.04888 0.951 0.459 1.97 0.307 0.351 0.382 0.4182 1.36 0.683 2.7 0.457 0.335 0.173 0.7621 1.58 0.819 3.05 PRS_PLINK_1.99526231496888e.06 687.4 Disturbance of skin sensation Both 1962 21730 13 dermatologic firebrick 21730, 1962 5470, 485 5444, 475 5380, 473 5426, 528 0.0356 0.0234 0.129 0.8884 1.04 0.99 1.08 -0.0142 0.0672 0.833 0.07959 0.986 0.864 1.12 -0.00602 0.0674 0.929 0.03211 0.994 0.871 1.13 0.0993 0.0657 0.131 0.8825 1.1 0.971 1.26 PRS_PLINK_1.99526231496888e.06 689 Disorder of skin and subcutaneous tissue NOS Both 3950 41432 13 dermatologic firebrick 41432, 3950 10420, 1043 10365, 1020 10386, 894 10250, 993 -0.0229 0.0167 0.17 0.769 0.977 0.946 1.01 -0.016 0.0462 0.728 0.1377 0.984 0.899 1.08 -0.151 0.0476 0.00151 2.821 0.86 0.783 0.944 -0.031 0.0465 0.505 0.2965 0.969 0.885 1.06 PRS_PLINK_1.99526231496888e.06 690 Erythematosquamous dermatosis Both 46 529 13 dermatologic firebrick 529, 46 134, 11 130, 15 132, 9 132, 11 -0.102 0.15 0.498 0.3031 0.903 0.673 1.21 0.327 0.396 0.408 0.3894 1.39 0.639 3.01 -0.221 0.439 0.615 0.2113 0.802 0.339 1.9 0.0107 0.422 0.98 0.008883 1.01 0.442 2.31 PRS_PLINK_1.99526231496888e.06 690.1 Seborrheic dermatitis Both 36 386 13 dermatologic firebrick 386, 36 96, 10 96, 11 96, 8 97, 7 -0.241 0.182 0.184 0.736 0.786 0.55 1.12 0.122 0.436 0.779 0.1083 1.13 0.48 2.66 -0.211 0.481 0.661 0.1795 0.81 0.316 2.08 -0.37 0.496 0.456 0.3413 0.691 0.261 1.83 PRS_PLINK_1.99526231496888e.06 691 Congenital anomalies of skin Both 80 876 13 dermatologic firebrick 876, 80 221, 30 215, 22 219, 17 219, 11 -0.313 0.127 0.0135 1.869 0.732 0.571 0.938 -0.249 0.292 0.393 0.4051 0.779 0.44 1.38 -0.582 0.311 0.0616 1.21 0.559 0.303 1.03 -0.958 0.354 0.00685 2.165 0.384 0.192 0.768 PRS_PLINK_1.99526231496888e.06 694 Dyschromia and Vitiligo Both 723 7202 13 dermatologic firebrick 7202, 723 1799, 200 1801, 170 1812, 191 1787, 160 -0.0601 0.0399 0.131 0.8819 0.942 0.871 1.02 -0.155 0.109 0.156 0.8063 0.857 0.691 1.06 -0.051 0.106 0.631 0.2002 0.95 0.772 1.17 -0.214 0.111 0.0539 1.269 0.807 0.65 1 PRS_PLINK_1.99526231496888e.06 694.1 Vitiligo Both 39 445 13 dermatologic firebrick 445, 39 113, 17 110, 6 110, 6 111, 10 -0.0949 0.181 0.6 0.222 0.91 0.638 1.3 -1.06 0.473 0.0247 1.608 0.346 0.137 0.873 -0.975 0.463 0.0351 1.454 0.377 0.152 0.934 -0.463 0.405 0.253 0.5975 0.629 0.284 1.39 PRS_PLINK_1.99526231496888e.06 694.2 Other dyschromia Both 597 5704 13 dermatologic firebrick 5704, 597 1444, 167 1411, 144 1434, 149 1413, 135 -0.0789 0.0441 0.0735 1.134 0.924 0.848 1.01 -0.11 0.119 0.357 0.4478 0.896 0.709 1.13 -0.106 0.118 0.369 0.4328 0.899 0.713 1.13 -0.191 0.121 0.115 0.9407 0.826 0.651 1.05 PRS_PLINK_1.99526231496888e.06 694.3 Vascular disorders of skin Both 68 847 13 dermatologic firebrick 847, 68 214, 11 211, 16 211, 27 211, 14 0.148 0.122 0.225 0.6477 1.16 0.913 1.47 0.385 0.381 0.312 0.5054 1.47 0.696 3.1 0.911 0.358 0.011 1.957 2.49 1.23 5.02 0.341 0.395 0.387 0.4123 1.41 0.649 3.05 PRS_PLINK_1.99526231496888e.06 695 Erythematous conditions Both 1513 17392 13 dermatologic firebrick 17392, 1513 4356, 376 4349, 383 4360, 378 4320, 376 0.00487 0.0268 0.856 0.06746 1 0.953 1.06 0.0206 0.0756 0.785 0.1053 1.02 0.88 1.18 0.00348 0.0758 0.963 0.01619 1 0.865 1.16 0.00954 0.076 0.9 0.04572 1.01 0.87 1.17 PRS_PLINK_1.99526231496888e.06 695.1 Toxic erythema Both 66 829 13 dermatologic firebrick 829, 66 216, 11 208, 16 198, 20 207, 19 0.22 0.119 0.0638 1.195 1.25 0.987 1.57 0.374 0.384 0.329 0.4827 1.45 0.686 3.08 0.624 0.371 0.0924 1.034 1.87 0.902 3.86 0.575 0.372 0.122 0.9143 1.78 0.858 3.68 PRS_PLINK_1.99526231496888e.06 695.2 Bullous dermatoses Both 87 966 13 dermatologic firebrick 966, 87 241, 20 242, 22 241, 20 241, 25 0.0339 0.108 0.753 0.123 1.03 0.837 1.28 0.0821 0.312 0.792 0.1012 1.09 0.59 2 0.0374 0.318 0.907 0.04262 1.04 0.556 1.94 0.282 0.309 0.362 0.4414 1.33 0.723 2.43 PRS_PLINK_1.99526231496888e.06 695.21 Dermatitis herpetiformis Both 36 395 13 dermatologic firebrick 395, 36 98, 8 99, 8 99, 11 98, 9 -0.0337 0.163 0.837 0.07747 0.967 0.702 1.33 -0.0267 0.49 0.957 0.01928 0.974 0.373 2.54 0.385 0.462 0.404 0.3936 1.47 0.595 3.64 0.273 0.489 0.577 0.2385 1.31 0.503 3.43 PRS_PLINK_1.99526231496888e.06 695.22 Pemphigus and pemphigoid Both 48 516 13 dermatologic firebrick 516, 48 130, 10 128, 14 129, 7 129, 17 0.15 0.141 0.286 0.5434 1.16 0.882 1.53 0.273 0.418 0.514 0.2891 1.31 0.579 2.98 -0.338 0.475 0.476 0.322 0.713 0.281 1.81 0.478 0.401 0.233 0.6326 1.61 0.735 3.54 PRS_PLINK_1.99526231496888e.06 695.3 Rosacea Both 224 2212 13 dermatologic firebrick 2212, 224 553, 49 552, 61 553, 60 553, 54 0.0532 0.0686 0.438 0.3589 1.05 0.922 1.21 0.229 0.199 0.249 0.604 1.26 0.852 1.86 0.201 0.2 0.314 0.5032 1.22 0.827 1.81 0.0912 0.205 0.656 0.1829 1.1 0.733 1.64 PRS_PLINK_1.99526231496888e.06 695.4 Lupus (localized and systemic) Both 219 3148 13 dermatologic firebrick 3148, 219 789, 54 788, 55 785, 62 786, 48 -0.00253 0.0712 0.972 0.01247 0.997 0.868 1.15 0.0103 0.196 0.958 0.01859 1.01 0.688 1.48 0.163 0.191 0.393 0.4052 1.18 0.81 1.71 -0.0937 0.202 0.643 0.1915 0.911 0.612 1.35 PRS_PLINK_1.99526231496888e.06 695.41 Cutaneous lupus erythematosus Both 71 955 13 dermatologic firebrick 955, 71 240, 14 238, 25 238, 19 239, 13 -0.173 0.127 0.174 0.7601 0.841 0.656 1.08 0.518 0.336 0.123 0.9086 1.68 0.869 3.24 0.252 0.35 0.471 0.3271 1.29 0.648 2.56 -0.154 0.383 0.688 0.1623 0.857 0.404 1.82 PRS_PLINK_1.99526231496888e.06 695.42 Systemic lupus erythematosus Both 179 2643 13 dermatologic firebrick 2643, 179 661, 50 665, 41 663, 47 654, 41 0.021 0.0778 0.788 0.1037 1.02 0.877 1.19 -0.206 0.215 0.337 0.4718 0.814 0.534 1.24 -0.0282 0.208 0.892 0.04963 0.972 0.647 1.46 -0.165 0.215 0.444 0.3527 0.848 0.556 1.29 PRS_PLINK_1.99526231496888e.06 695.7 Prurigo and Lichen Both 527 5652 13 dermatologic firebrick 5652, 527 1412, 135 1417, 138 1411, 118 1409, 136 -0.0161 0.0459 0.725 0.1396 0.984 0.899 1.08 0.0162 0.126 0.898 0.04664 1.02 0.793 1.3 -0.129 0.131 0.323 0.4913 0.879 0.68 1.14 0.00702 0.127 0.956 0.01959 1.01 0.785 1.29 PRS_PLINK_1.99526231496888e.06 695.8 Other specified erythematous conditions Both 146 1752 13 dermatologic firebrick 1752, 146 438, 34 438, 37 438, 35 438, 40 0.0147 0.0824 0.859 0.06608 1.01 0.863 1.19 0.0982 0.244 0.687 0.1629 1.1 0.684 1.78 0.025 0.246 0.919 0.0367 1.03 0.634 1.66 0.154 0.239 0.519 0.2851 1.17 0.731 1.86 PRS_PLINK_1.99526231496888e.06 695.81 Erythema nodosum Both 55 604 13 dermatologic firebrick 604, 55 151, 14 156, 19 146, 11 151, 11 -0.226 0.146 0.123 0.9117 0.798 0.599 1.06 0.233 0.363 0.52 0.2837 1.26 0.62 2.57 -0.2 0.406 0.622 0.2059 0.819 0.37 1.81 -0.284 0.403 0.48 0.3185 0.753 0.342 1.66 PRS_PLINK_1.99526231496888e.06 695.9 Unspecified erythematous condition Both 280 3288 13 dermatologic firebrick 3288, 280 821, 78 822, 65 825, 69 819, 68 -0.012 0.0632 0.849 0.07101 0.988 0.873 1.12 -0.18 0.173 0.3 0.5234 0.835 0.595 1.17 -0.125 0.171 0.466 0.3318 0.883 0.631 1.23 -0.13 0.172 0.45 0.3469 0.878 0.627 1.23 PRS_PLINK_1.99526231496888e.06 696 Psoriasis and related disorders Both 1320 16391 13 dermatologic firebrick 16391, 1320 4112, 367 4090, 300 4094, 346 4093, 307 -0.0301 0.0289 0.297 0.5271 0.97 0.917 1.03 -0.196 0.0808 0.0154 1.811 0.822 0.702 0.963 -0.0466 0.0781 0.551 0.259 0.954 0.819 1.11 -0.161 0.0804 0.0446 1.351 0.851 0.727 0.996 PRS_PLINK_1.99526231496888e.06 696.4 Psoriasis Both 1285 16044 13 dermatologic firebrick 16044, 1285 4016, 352 4037, 295 3989, 336 4000, 302 -0.0236 0.0292 0.419 0.3779 0.977 0.922 1.03 -0.181 0.0819 0.0271 1.567 0.835 0.711 0.98 -0.0314 0.0794 0.693 0.1596 0.969 0.829 1.13 -0.137 0.0815 0.0917 1.038 0.872 0.743 1.02 PRS_PLINK_1.99526231496888e.06 696.41 Psoriasis vulgaris Both 954 12132 13 dermatologic firebrick 12132, 954 3034, 255 3031, 224 3038, 253 3027, 222 -0.022 0.0337 0.515 0.2884 0.978 0.916 1.05 -0.127 0.0949 0.18 0.7458 0.88 0.731 1.06 -0.00549 0.0923 0.953 0.0211 0.995 0.83 1.19 -0.122 0.0952 0.202 0.695 0.886 0.735 1.07 PRS_PLINK_1.99526231496888e.06 696.42 Psoriatic arthropathy Both 450 5291 13 dermatologic firebrick 5291, 450 1324, 125 1322, 93 1349, 118 1296, 114 0.0137 0.0491 0.781 0.1075 1.01 0.921 1.12 -0.294 0.141 0.0376 1.425 0.745 0.565 0.983 -0.0727 0.134 0.586 0.2321 0.93 0.716 1.21 -0.067 0.135 0.618 0.2087 0.935 0.718 1.22 PRS_PLINK_1.99526231496888e.06 697 Sarcoidosis Both 268 4024 13 dermatologic firebrick 4024, 268 1008, 60 1005, 48 1004, 80 1006, 80 0.129 0.0611 0.0352 1.453 1.14 1.01 1.28 -0.235 0.196 0.231 0.6366 0.791 0.538 1.16 0.29 0.175 0.0979 1.009 1.34 0.948 1.88 0.29 0.175 0.0969 1.013 1.34 0.949 1.88 PRS_PLINK_1.99526231496888e.06 698 Pruritus and related conditions Both 550 5719 13 dermatologic firebrick 5719, 550 1454, 156 1405, 118 1458, 144 1401, 132 -0.0135 0.0443 0.761 0.1185 0.987 0.904 1.08 -0.258 0.127 0.043 1.367 0.773 0.602 0.992 -0.0957 0.121 0.43 0.3667 0.909 0.717 1.15 -0.139 0.124 0.262 0.582 0.87 0.682 1.11 PRS_PLINK_1.99526231496888e.06 700 Corns and callosities Both 185 2154 13 dermatologic firebrick 2154, 185 539, 41 539, 52 539, 50 536, 42 -0.0231 0.0774 0.765 0.1161 0.977 0.84 1.14 0.229 0.215 0.286 0.5437 1.26 0.826 1.91 0.211 0.216 0.329 0.4827 1.24 0.808 1.89 0.023 0.226 0.919 0.03679 1.02 0.658 1.59 PRS_PLINK_1.99526231496888e.06 701 Other hypertrophic and atrophic conditions of skin Both 3312 34327 13 dermatologic firebrick 34327, 3312 8616, 841 8594, 803 8676, 818 8430, 850 0.0155 0.0181 0.392 0.4071 1.02 0.98 1.05 -0.0415 0.0516 0.422 0.3747 0.959 0.867 1.06 -0.0321 0.0514 0.533 0.2736 0.968 0.876 1.07 0.0344 0.0511 0.501 0.2999 1.03 0.936 1.14 PRS_PLINK_1.99526231496888e.06 701.1 Keratoderma, acquired Both 54 590 13 dermatologic firebrick 590, 54 149, 24 145, 8 149, 10 146, 12 -0.227 0.15 0.129 0.8884 0.797 0.594 1.07 -1.04 0.404 0.0102 1.993 0.354 0.16 0.781 -0.877 0.383 0.0219 1.66 0.416 0.196 0.88 -0.654 0.36 0.0692 1.16 0.52 0.257 1.05 PRS_PLINK_1.99526231496888e.06 701.2 Scar conditions and fibrosis of skin Both 1716 17453 13 dermatologic firebrick 17453, 1716 4360, 421 4370, 411 4394, 440 4324, 444 0.018 0.0252 0.477 0.3219 1.02 0.969 1.07 -0.028 0.0725 0.699 0.1555 0.972 0.844 1.12 0.0436 0.0714 0.542 0.2663 1.04 0.908 1.2 0.0657 0.0714 0.357 0.4472 1.07 0.929 1.23 PRS_PLINK_1.99526231496888e.06 701.3 Circumscribed scleroderma Both 38 428 13 dermatologic firebrick 428, 38 107, 10 107, 6 107, 10 107, 12 0.235 0.159 0.139 0.8562 1.26 0.926 1.73 -0.562 0.507 0.268 0.5721 0.57 0.211 1.54 -0.0348 0.458 0.939 0.02713 0.966 0.393 2.37 0.199 0.439 0.65 0.1868 1.22 0.516 2.88 PRS_PLINK_1.99526231496888e.06 701.4 Keloid scar Both 162 1675 13 dermatologic firebrick 1675, 162 421, 35 421, 52 419, 36 414, 39 -0.0225 0.0812 0.781 0.1071 0.978 0.834 1.15 0.397 0.226 0.0795 1.1 1.49 0.954 2.32 0.0231 0.242 0.924 0.03439 1.02 0.637 1.64 0.134 0.239 0.576 0.2399 1.14 0.716 1.83 PRS_PLINK_1.99526231496888e.06 701.5 Abnormal granulation tissue Both 338 3396 13 dermatologic firebrick 3396, 338 850, 78 851, 89 848, 81 847, 90 0.0554 0.0563 0.326 0.4874 1.06 0.946 1.18 0.14 0.162 0.387 0.4119 1.15 0.838 1.58 0.0565 0.165 0.732 0.1358 1.06 0.766 1.46 0.149 0.161 0.356 0.4488 1.16 0.846 1.59 PRS_PLINK_1.99526231496888e.06 701.6 Acquired acanthosis nigricans Both 64 767 13 dermatologic firebrick 767, 64 193, 26 190, 9 193, 13 189, 16 -0.102 0.131 0.437 0.3593 0.903 0.699 1.17 -0.975 0.38 0.0103 1.986 0.377 0.179 0.795 -0.621 0.343 0.0708 1.15 0.538 0.274 1.05 -0.464 0.326 0.155 0.8102 0.629 0.332 1.19 PRS_PLINK_1.99526231496888e.06 702 Degenerative skin conditions and other dermatoses Both 3821 38063 13 dermatologic firebrick 38063, 3821 9576, 932 9469, 1012 9537, 942 9473, 934 0.000753 0.017 0.965 0.01566 1 0.968 1.03 0.0951 0.0476 0.0459 1.339 1.1 1 1.21 0.0143 0.0484 0.768 0.1148 1.01 0.923 1.12 0.0141 0.0486 0.771 0.1129 1.01 0.922 1.12 PRS_PLINK_1.99526231496888e.06 702.1 Actinic keratosis Both 1753 17669 13 dermatologic firebrick 17669, 1753 4438, 416 4393, 468 4422, 436 4412, 432 0.000922 0.025 0.971 0.01295 1 0.953 1.05 0.128 0.0706 0.0703 1.153 1.14 0.989 1.31 0.0548 0.0717 0.445 0.3521 1.06 0.918 1.22 0.0468 0.0719 0.515 0.288 1.05 0.91 1.21 PRS_PLINK_1.99526231496888e.06 702.2 Seborrheic keratosis Both 2208 21594 13 dermatologic firebrick 21594, 2208 5409, 550 5387, 577 5406, 539 5386, 542 -0.000681 0.0223 0.976 0.01069 0.999 0.957 1.04 0.0514 0.0626 0.411 0.3859 1.05 0.931 1.19 -0.0234 0.0636 0.713 0.1469 0.977 0.862 1.11 -0.0101 0.0636 0.874 0.05861 0.99 0.874 1.12 PRS_PLINK_1.99526231496888e.06 703 Diseases of nail, NOS Both 230 2525 13 dermatologic firebrick 2525, 230 631, 63 631, 57 638, 48 624, 62 -0.00524 0.0697 0.94 0.02685 0.995 0.868 1.14 -0.0927 0.189 0.624 0.205 0.911 0.629 1.32 -0.278 0.197 0.159 0.7979 0.758 0.515 1.12 -0.0111 0.186 0.952 0.02116 0.989 0.687 1.42 PRS_PLINK_1.99526231496888e.06 703.1 Ingrowing nail Both 620 7152 13 dermatologic firebrick 7152, 620 1821, 137 1760, 150 1805, 149 1763, 184 0.117 0.0403 0.00357 2.447 1.12 1.04 1.22 0.119 0.122 0.332 0.479 1.13 0.886 1.43 0.105 0.122 0.392 0.407 1.11 0.874 1.41 0.33 0.117 0.00489 2.31 1.39 1.11 1.75 PRS_PLINK_1.99526231496888e.06 704 Diseases of hair and hair follicles Both 3837 39206 13 dermatologic firebrick 39206, 3837 9802, 975 9850, 903 9779, 935 9762, 1022 0.0415 0.0167 0.0131 1.882 1.04 1.01 1.08 -0.0804 0.0483 0.0962 1.017 0.923 0.839 1.01 -0.0395 0.0479 0.41 0.387 0.961 0.875 1.06 0.0534 0.047 0.256 0.5921 1.05 0.962 1.16 PRS_PLINK_1.99526231496888e.06 704.1 Alopecia Both 83 992 13 dermatologic firebrick 992, 83 248, 16 247, 24 248, 23 248, 20 -0.000396 0.113 0.997 0.001213 1 0.801 1.25 0.346 0.325 0.286 0.543 1.41 0.748 2.67 0.374 0.328 0.255 0.593 1.45 0.763 2.77 0.179 0.339 0.598 0.2234 1.2 0.615 2.33 PRS_PLINK_1.99526231496888e.06 704.8 Other specified diseases of hair and hair follicles Both 58 561 13 dermatologic firebrick 561, 58 142, 16 139, 12 143, 13 137, 17 0.0848 0.128 0.506 0.2958 1.09 0.848 1.4 -0.273 0.391 0.485 0.314 0.761 0.353 1.64 -0.272 0.386 0.481 0.3183 0.762 0.358 1.62 0.089 0.367 0.808 0.09242 1.09 0.532 2.24 PRS_PLINK_1.99526231496888e.06 705 Disorders of sweat glands Both 139 1822 13 dermatologic firebrick 1822, 139 456, 36 457, 26 453, 35 456, 42 0.0488 0.087 0.575 0.2404 1.05 0.885 1.25 -0.324 0.259 0.211 0.6754 0.723 0.436 1.2 -0.0242 0.242 0.92 0.03602 0.976 0.608 1.57 0.16 0.232 0.491 0.3093 1.17 0.744 1.85 PRS_PLINK_1.99526231496888e.06 705.3 Hidradenitis Both 114 1494 13 dermatologic firebrick 1494, 114 376, 34 371, 21 380, 27 367, 32 -0.00648 0.0959 0.946 0.02404 0.994 0.823 1.2 -0.441 0.279 0.115 0.9407 0.644 0.372 1.11 -0.238 0.263 0.365 0.4378 0.788 0.471 1.32 -0.0309 0.253 0.903 0.04452 0.97 0.591 1.59 PRS_PLINK_1.99526231496888e.06 705.8 Hyperhidrosis Both 361 4228 13 dermatologic firebrick 4228, 361 1062, 78 1050, 81 1057, 91 1057, 110 0.129 0.052 0.0135 1.871 1.14 1.03 1.26 0.0511 0.163 0.754 0.1227 1.05 0.764 1.45 0.16 0.159 0.315 0.5011 1.17 0.859 1.6 0.358 0.153 0.0194 1.712 1.43 1.06 1.93 PRS_PLINK_1.99526231496888e.06 706 Diseases of sebaceous glands Both 6063 61421 13 dermatologic firebrick 61421, 6063 15338, 1510 15390, 1408 15590, 1584 15084, 1558 0.0363 0.0134 0.00654 2.185 1.04 1.01 1.06 -0.0723 0.0388 0.0622 1.206 0.93 0.862 1 0.0316 0.0377 0.402 0.3955 1.03 0.959 1.11 0.0532 0.0379 0.161 0.7928 1.05 0.979 1.14 PRS_PLINK_1.99526231496888e.06 706.1 Acne Both 57 622 13 dermatologic firebrick 622, 57 157, 10 154, 8 154, 21 156, 18 0.29 0.129 0.0244 1.613 1.34 1.04 1.72 -0.211 0.458 0.644 0.1912 0.809 0.33 1.98 0.837 0.39 0.0321 1.493 2.31 1.07 4.96 0.567 0.391 0.147 0.8317 1.76 0.819 3.79 PRS_PLINK_1.99526231496888e.06 706.2 Sebaceous cyst Both 6421 64821 13 dermatologic firebrick 64821, 6421 16201, 1607 16292, 1521 16352, 1653 15957, 1636 0.0264 0.013 0.042 1.376 1.03 1 1.05 -0.0602 0.0374 0.108 0.9657 0.942 0.875 1.01 0.0184 0.0368 0.617 0.21 1.02 0.948 1.09 0.0384 0.0369 0.298 0.5251 1.04 0.967 1.12 PRS_PLINK_1.99526231496888e.06 707 Chronic ulcer of skin Both 823 13259 13 dermatologic firebrick 13259, 823 3329, 201 3314, 191 3305, 206 3308, 225 0.0704 0.0348 0.0431 1.366 1.07 1 1.15 -0.0482 0.104 0.642 0.1928 0.953 0.778 1.17 0.0293 0.102 0.773 0.1117 1.03 0.843 1.26 0.123 0.0998 0.219 0.6605 1.13 0.93 1.38 PRS_PLINK_1.99526231496888e.06 707.1 Decubitus ulcer Both 426 6025 13 dermatologic firebrick 6025, 426 1515, 102 1498, 103 1513, 114 1497, 107 0.0418 0.0487 0.39 0.4089 1.04 0.948 1.15 0.0169 0.143 0.906 0.04288 1.02 0.768 1.35 0.114 0.14 0.418 0.379 1.12 0.851 1.48 0.0701 0.142 0.622 0.2061 1.07 0.812 1.42 PRS_PLINK_1.99526231496888e.06 709 Diffuse diseases of connective tissue Both 2182 24985 13 dermatologic firebrick 24985, 2182 6304, 549 6229, 523 6219, 581 6228, 528 0.0124 0.0222 0.575 0.2406 1.01 0.969 1.06 -0.0365 0.0636 0.566 0.2474 0.964 0.851 1.09 0.0716 0.0621 0.249 0.6042 1.07 0.951 1.21 -0.029 0.0635 0.647 0.1888 0.971 0.858 1.1 PRS_PLINK_1.99526231496888e.06 709.2 Sicca syndrome Both 260 3817 13 dermatologic firebrick 3817, 260 961, 61 953, 60 959, 70 944, 69 0.11 0.0618 0.0759 1.12 1.12 0.989 1.26 0.0261 0.186 0.888 0.05141 1.03 0.713 1.48 0.165 0.179 0.358 0.4466 1.18 0.83 1.68 0.164 0.18 0.362 0.4416 1.18 0.828 1.68 PRS_PLINK_1.99526231496888e.06 709.3 Systemic sclerosis Both 90 1293 13 dermatologic firebrick 1293, 90 326, 23 324, 19 322, 23 321, 25 0.0949 0.106 0.369 0.4329 1.1 0.894 1.35 -0.163 0.311 0.599 0.2224 0.849 0.462 1.56 -0.0458 0.296 0.877 0.05685 0.955 0.534 1.71 0.109 0.292 0.71 0.1489 1.12 0.629 1.98 PRS_PLINK_1.99526231496888e.06 709.6 Other specified diffuse diseases of connective tissue Both 32 505 13 dermatologic firebrick 505, 32 130, 6 123, 4 128, 8 124, 14 0.323 0.158 0.0409 1.388 1.38 1.01 1.88 -0.495 0.584 0.396 0.4022 0.609 0.194 1.91 0.245 0.516 0.635 0.1973 1.28 0.465 3.51 0.805 0.475 0.0898 1.047 2.24 0.883 5.67 PRS_PLINK_1.99526231496888e.06 709.7 Unspecified diffuse connective tissue disease Both 1812 19648 13 dermatologic firebrick 19648, 1812 4913, 462 4923, 445 4914, 482 4893, 422 -0.0146 0.0246 0.554 0.2568 0.986 0.939 1.03 -0.0411 0.0693 0.553 0.2571 0.96 0.838 1.1 0.0442 0.0681 0.517 0.2868 1.05 0.915 1.19 -0.0896 0.0703 0.202 0.6939 0.914 0.797 1.05 PRS_PLINK_1.99526231496888e.06 710 Osteomyelitis, periostitis, and other infections involving bone Both 290 4237 14 musculoskeletal darkolivegreen 4237, 290 1055, 77 1059, 61 1060, 66 1058, 86 0.0808 0.0594 0.174 0.7603 1.08 0.965 1.22 -0.217 0.176 0.216 0.6656 0.805 0.571 1.14 -0.146 0.172 0.393 0.4053 0.864 0.617 1.21 0.11 0.162 0.499 0.3021 1.12 0.812 1.53 PRS_PLINK_1.99526231496888e.06 710.1 Osteomyelitis Both 266 3944 14 musculoskeletal darkolivegreen 3944, 266 985, 74 988, 54 994, 62 973, 76 0.0609 0.0628 0.332 0.4784 1.06 0.94 1.2 -0.306 0.183 0.0941 1.026 0.736 0.515 1.05 -0.174 0.176 0.324 0.4897 0.841 0.595 1.19 0.0454 0.168 0.788 0.1037 1.05 0.752 1.46 PRS_PLINK_1.99526231496888e.06 710.12 Chronic osteomyelitis Both 99 1413 14 musculoskeletal darkolivegreen 1413, 99 358, 27 350, 16 353, 30 352, 26 0.0956 0.102 0.351 0.455 1.1 0.9 1.35 -0.495 0.318 0.119 0.923 0.61 0.327 1.14 0.128 0.271 0.638 0.195 1.14 0.668 1.93 0.0463 0.28 0.868 0.06132 1.05 0.606 1.81 PRS_PLINK_1.99526231496888e.06 710.19 Unspecified osteomyelitis Both 176 2796 14 musculoskeletal darkolivegreen 2796, 176 698, 49 698, 41 700, 32 696, 54 0.0483 0.0768 0.53 0.276 1.05 0.903 1.22 -0.158 0.215 0.463 0.3341 0.854 0.56 1.3 -0.419 0.229 0.0671 1.173 0.658 0.42 1.03 0.0863 0.202 0.669 0.1743 1.09 0.734 1.62 PRS_PLINK_1.99526231496888e.06 711 Arthropathy associated with infections Both 246 3048 14 musculoskeletal darkolivegreen 3048, 246 762, 48 769, 62 758, 69 759, 67 0.139 0.0634 0.0279 1.554 1.15 1.02 1.3 0.252 0.196 0.199 0.7016 1.29 0.876 1.89 0.381 0.193 0.0484 1.315 1.46 1 2.14 0.36 0.195 0.0651 1.187 1.43 0.978 2.1 PRS_PLINK_1.99526231496888e.06 711.1 Pyogenic arthritis Both 183 2351 14 musculoskeletal darkolivegreen 2351, 183 590, 32 589, 48 585, 53 587, 50 0.161 0.0731 0.0274 1.563 1.18 1.02 1.36 0.413 0.231 0.0742 1.13 1.51 0.96 2.38 0.528 0.228 0.0203 1.692 1.7 1.09 2.65 0.476 0.232 0.0401 1.397 1.61 1.02 2.54 PRS_PLINK_1.99526231496888e.06 712 Infective connective tissue disorders Both 46 569 14 musculoskeletal darkolivegreen 569, 46 144, 7 141, 11 142, 13 142, 15 0.283 0.142 0.046 1.337 1.33 1.01 1.75 0.378 0.466 0.418 0.3793 1.46 0.585 3.64 0.66 0.456 0.148 0.8304 1.93 0.792 4.73 0.724 0.445 0.104 0.9826 2.06 0.862 4.94 PRS_PLINK_1.99526231496888e.06 713 Arthropathy associated with other disorders classified elsewhere Both 65 1078 14 musculoskeletal darkolivegreen 1078, 65 271, 13 266, 14 268, 23 270, 15 0.114 0.122 0.352 0.453 1.12 0.882 1.42 0.0996 0.376 0.791 0.1019 1.1 0.529 2.31 0.646 0.345 0.0615 1.211 1.91 0.969 3.75 0.133 0.37 0.719 0.1431 1.14 0.553 2.36 PRS_PLINK_1.99526231496888e.06 713.5 Arthropathy associated with neurological disorders Both 15 445 14 musculoskeletal darkolivegreen 445, 15 111, 2 111, 2 114, 9 108, 2 0.162 0.231 0.482 0.3168 1.18 0.748 1.85 -0.524 0.856 0.54 0.2676 0.592 0.111 3.17 1.37 0.658 0.038 1.42 3.92 1.08 14.2 0.221 0.806 0.784 0.1058 1.25 0.257 6.05 PRS_PLINK_1.99526231496888e.06 714 Rheumatoid arthritis and other inflammatory polyarthropathies Both 2698 35492 14 musculoskeletal darkolivegreen 35492, 2698 8867, 678 8900, 627 8948, 665 8762, 728 0.0321 0.0197 0.104 0.982 1.03 0.993 1.07 -0.0793 0.0574 0.167 0.7773 0.924 0.826 1.03 -0.0223 0.0566 0.693 0.1592 0.978 0.875 1.09 0.0918 0.0555 0.098 1.009 1.1 0.983 1.22 PRS_PLINK_1.99526231496888e.06 714.1 Rheumatoid arthritis Both 2421 32196 14 musculoskeletal darkolivegreen 32196, 2421 8057, 618 8027, 567 8094, 581 8004, 655 0.0246 0.0209 0.238 0.6228 1.02 0.984 1.07 -0.0799 0.0602 0.184 0.7341 0.923 0.82 1.04 -0.0606 0.0599 0.312 0.5063 0.941 0.837 1.06 0.0729 0.0583 0.211 0.6766 1.08 0.96 1.21 PRS_PLINK_1.99526231496888e.06 715 Other inflammatory spondylopathies Both 1023 12060 14 musculoskeletal darkolivegreen 12060, 1023 3012, 277 3015, 244 3038, 248 2992, 254 -0.0142 0.0326 0.664 0.1776 0.986 0.925 1.05 -0.125 0.0913 0.17 0.7705 0.882 0.738 1.05 -0.111 0.091 0.221 0.6549 0.895 0.748 1.07 -0.0791 0.0906 0.383 0.4171 0.924 0.774 1.1 PRS_PLINK_1.99526231496888e.06 715.1 Sacroiliitis NEC Both 72 897 14 musculoskeletal darkolivegreen 897, 72 225, 23 227, 13 221, 18 224, 18 -0.046 0.123 0.709 0.1494 0.955 0.75 1.22 -0.576 0.35 0.0995 1.002 0.562 0.283 1.12 -0.176 0.32 0.582 0.2349 0.838 0.447 1.57 -0.25 0.321 0.436 0.3603 0.779 0.415 1.46 PRS_PLINK_1.99526231496888e.06 715.2 Ankylosing spondylitis Both 379 4404 14 musculoskeletal darkolivegreen 4404, 379 1121, 96 1080, 92 1109, 89 1093, 102 0.0447 0.0522 0.391 0.4076 1.05 0.944 1.16 0.000848 0.151 0.996 0.00195 1 0.744 1.35 -0.0443 0.153 0.772 0.1126 0.957 0.709 1.29 0.0978 0.148 0.508 0.2943 1.1 0.826 1.47 PRS_PLINK_1.99526231496888e.06 716 Other arthropathies Both 23477 196989 14 musculoskeletal darkolivegreen 196989, 23477 49273, 5603 49258, 5739 49807, 6031 48582, 6096 0.0332 0.00685 1.23e-06 5.909 1.03 1.02 1.05 0.0193 0.0199 0.333 0.4777 1.02 0.98 1.06 0.0492 0.0197 0.0124 1.907 1.05 1.01 1.09 0.0761 0.0197 0.00011 3.959 1.08 1.04 1.12 PRS_PLINK_1.99526231496888e.06 716.1 Unspecified polyarthropathy or polyarthritis Both 2074 25167 14 musculoskeletal darkolivegreen 25167, 2074 6321, 481 6314, 524 6264, 499 6260, 570 0.0502 0.0225 0.0258 1.588 1.05 1.01 1.1 0.088 0.0655 0.179 0.7464 1.09 0.96 1.24 0.0449 0.0663 0.498 0.3031 1.05 0.919 1.19 0.181 0.0644 0.00497 2.304 1.2 1.06 1.36 PRS_PLINK_1.99526231496888e.06 716.2 Unspecified monoarthritis Both 9596 111168 14 musculoskeletal darkolivegreen 111168, 9596 27962, 2354 27582, 2362 27912, 2385 27672, 2491 0.0308 0.0105 0.00345 2.462 1.03 1.01 1.05 0.0169 0.0303 0.578 0.2379 1.02 0.958 1.08 0.0159 0.0303 0.6 0.222 1.02 0.957 1.08 0.0668 0.03 0.026 1.585 1.07 1.01 1.13 PRS_PLINK_1.99526231496888e.06 716.9 Arthropathy NOS Both 22494 194363 14 musculoskeletal darkolivegreen 194363, 22494 48597, 5375 48565, 5494 49155, 5799 47977, 5818 0.032 0.00699 4.7e-06 5.328 1.03 1.02 1.05 0.0178 0.0203 0.38 0.4206 1.02 0.978 1.06 0.0519 0.0201 0.00969 2.014 1.05 1.01 1.1 0.0712 0.0201 0.000389 3.41 1.07 1.03 1.12 PRS_PLINK_1.99526231496888e.06 717 Polymyalgia Rheumatica Both 598 7700 14 musculoskeletal darkolivegreen 7700, 598 1936, 148 1915, 145 1930, 137 1918, 168 0.0471 0.0416 0.257 0.5895 1.05 0.966 1.14 -0.00767 0.121 0.949 0.02259 0.992 0.783 1.26 -0.0749 0.122 0.54 0.2678 0.928 0.73 1.18 0.145 0.117 0.215 0.6667 1.16 0.919 1.45 PRS_PLINK_1.99526231496888e.06 720 Spinal stenosis Both 2203 25800 14 musculoskeletal darkolivegreen 25800, 2203 6453, 528 6441, 522 6457, 576 6443, 574 0.0448 0.0219 0.0408 1.389 1.05 1 1.09 -0.0081 0.0641 0.9 0.04597 0.992 0.875 1.12 0.0869 0.0627 0.166 0.7806 1.09 0.965 1.23 0.0838 0.0628 0.182 0.7391 1.09 0.961 1.23 PRS_PLINK_1.99526231496888e.06 721 Spondylosis and allied disorders Both 4838 55921 14 musculoskeletal darkolivegreen 55921, 4838 13967, 1178 14014, 1205 13954, 1244 13972, 1208 0.0134 0.0149 0.368 0.4339 1.01 0.984 1.04 0.0211 0.0427 0.621 0.2072 1.02 0.939 1.11 0.0573 0.0424 0.177 0.7531 1.06 0.975 1.15 0.03 0.0427 0.482 0.3168 1.03 0.948 1.12 PRS_PLINK_1.99526231496888e.06 721.1 Spondylosis without myelopathy Both 3110 35929 14 musculoskeletal darkolivegreen 35929, 3110 9039, 760 8973, 772 8999, 795 8911, 782 0.0159 0.0186 0.393 0.4061 1.02 0.98 1.05 0.0239 0.0532 0.653 0.1849 1.02 0.923 1.14 0.0533 0.0529 0.313 0.504 1.05 0.951 1.17 0.0492 0.0531 0.354 0.451 1.05 0.947 1.17 PRS_PLINK_1.99526231496888e.06 721.2 Spondylosis with myelopathy Both 109 1333 14 musculoskeletal darkolivegreen 1333, 109 336, 30 332, 24 331, 34 333, 21 -0.0988 0.102 0.333 0.4778 0.906 0.742 1.11 -0.206 0.277 0.457 0.3402 0.814 0.472 1.4 0.106 0.261 0.683 0.1653 1.11 0.667 1.85 -0.38 0.288 0.187 0.7279 0.684 0.389 1.2 PRS_PLINK_1.99526231496888e.06 721.8 Other allied disorders of spine Both 211 2495 14 musculoskeletal darkolivegreen 2495, 211 630, 47 624, 55 619, 60 622, 48 0.0177 0.0712 0.804 0.09477 1.02 0.885 1.17 0.165 0.204 0.419 0.378 1.18 0.791 1.76 0.276 0.201 0.169 0.7716 1.32 0.889 1.96 0.0374 0.21 0.859 0.06615 1.04 0.688 1.57 PRS_PLINK_1.99526231496888e.06 722 Intervertebral disc disorders Both 6074 66959 14 musculoskeletal darkolivegreen 66959, 6074 16813, 1480 16834, 1468 16731, 1558 16565, 1561 0.034 0.0133 0.0107 1.969 1.03 1.01 1.06 -0.00799 0.0384 0.835 0.07825 0.992 0.92 1.07 0.0565 0.0379 0.136 0.8666 1.06 0.982 1.14 0.0722 0.0379 0.0569 1.245 1.07 0.998 1.16 PRS_PLINK_1.99526231496888e.06 722.1 Displacement of intervertebral disc Both 377 3878 14 musculoskeletal darkolivegreen 3878, 377 974, 98 976, 94 963, 96 965, 89 -0.0042 0.0545 0.939 0.02751 0.996 0.895 1.11 -0.0455 0.15 0.762 0.118 0.955 0.712 1.28 -0.0103 0.15 0.945 0.02451 0.99 0.738 1.33 -0.0715 0.153 0.64 0.1936 0.931 0.69 1.26 PRS_PLINK_1.99526231496888e.06 722.6 Degeneration of intervertebral disc Both 1811 21082 14 musculoskeletal darkolivegreen 21082, 1811 5273, 453 5277, 416 5267, 450 5260, 491 0.0567 0.0243 0.0195 1.711 1.06 1.01 1.11 -0.0851 0.0705 0.227 0.6432 0.918 0.8 1.05 -0.00328 0.0693 0.962 0.01673 0.997 0.87 1.14 0.0902 0.068 0.184 0.7342 1.09 0.958 1.25 PRS_PLINK_1.99526231496888e.06 722.8 Postlaminectomy syndrome Both 47 524 14 musculoskeletal darkolivegreen 524, 47 131, 11 131, 13 133, 12 128, 11 0.0025 0.151 0.987 0.005759 1 0.745 1.35 0.144 0.412 0.726 0.1389 1.16 0.515 2.59 0.0923 0.412 0.823 0.0847 1.1 0.489 2.46 -0.00768 0.422 0.985 0.006353 0.992 0.434 2.27 PRS_PLINK_1.99526231496888e.06 722.9 Other and unspecified disc disorder Both 2998 32921 14 musculoskeletal darkolivegreen 32921, 2998 8286, 736 8220, 698 8293, 782 8114, 778 0.0456 0.0189 0.016 1.796 1.05 1.01 1.09 -0.0424 0.055 0.441 0.3558 0.958 0.86 1.07 0.0604 0.0537 0.261 0.5839 1.06 0.956 1.18 0.0796 0.0538 0.139 0.8579 1.08 0.975 1.2 PRS_PLINK_1.99526231496888e.06 723 Other disorders of cervical region Both 335 3762 14 musculoskeletal darkolivegreen 3762, 335 947, 87 933, 75 943, 83 938, 90 0.0829 0.056 0.139 0.8568 1.09 0.973 1.21 -0.116 0.163 0.479 0.32 0.891 0.647 1.23 -0.0492 0.159 0.757 0.1208 0.952 0.697 1.3 0.0468 0.157 0.766 0.116 1.05 0.771 1.42 PRS_PLINK_1.99526231496888e.06 723.1 Torticollis Both 79 818 14 musculoskeletal darkolivegreen 818, 79 209, 19 201, 20 204, 15 204, 25 0.116 0.11 0.295 0.5308 1.12 0.904 1.39 0.0997 0.325 0.759 0.1198 1.1 0.585 2.09 -0.221 0.348 0.526 0.279 0.802 0.405 1.59 0.319 0.314 0.31 0.5092 1.38 0.744 2.55 PRS_PLINK_1.99526231496888e.06 724 Other and unspecified disorders of back Both 1386 15228 14 musculoskeletal darkolivegreen 15228, 1386 3805, 318 3828, 347 3803, 376 3790, 344 0.0339 0.0278 0.222 0.653 1.03 0.98 1.09 0.0844 0.0808 0.296 0.5284 1.09 0.929 1.27 0.166 0.0794 0.0363 1.441 1.18 1.01 1.38 0.0833 0.081 0.304 0.517 1.09 0.927 1.27 PRS_PLINK_1.99526231496888e.06 724.1 Disorders of sacrum Both 307 3198 14 musculoskeletal darkolivegreen 3198, 307 806, 84 796, 72 796, 80 799, 71 -0.0484 0.0599 0.419 0.3781 0.953 0.847 1.07 -0.132 0.167 0.43 0.3669 0.876 0.632 1.22 -0.0329 0.163 0.84 0.07562 0.968 0.703 1.33 -0.153 0.167 0.36 0.4435 0.858 0.618 1.19 PRS_PLINK_1.99526231496888e.06 724.2 Disorders of coccyx Both 311 3212 14 musculoskeletal darkolivegreen 3212, 311 818, 86 787, 73 807, 81 799, 71 -0.054 0.0597 0.366 0.4364 0.947 0.843 1.07 -0.116 0.166 0.486 0.3137 0.891 0.644 1.23 -0.0446 0.162 0.783 0.1063 0.956 0.697 1.31 -0.166 0.167 0.318 0.4977 0.847 0.611 1.17 PRS_PLINK_1.99526231496888e.06 724.8 Other symptoms referable to back Both 39 439 14 musculoskeletal darkolivegreen 439, 39 111, 7 109, 7 110, 16 109, 9 0.145 0.158 0.358 0.4458 1.16 0.849 1.57 -0.0565 0.517 0.913 0.03951 0.945 0.343 2.6 0.754 0.449 0.0931 1.031 2.13 0.882 5.13 0.252 0.486 0.604 0.2187 1.29 0.496 3.33 PRS_PLINK_1.99526231496888e.06 724.9 Other unspecified back disorders Both 1061 11786 14 musculoskeletal darkolivegreen 11786, 1061 2946, 227 2957, 275 2943, 286 2939, 272 0.0531 0.0317 0.0933 1.03 1.05 0.991 1.12 0.194 0.0932 0.0375 1.426 1.21 1.01 1.46 0.229 0.0924 0.0134 1.873 1.26 1.05 1.51 0.182 0.0934 0.0512 1.291 1.2 0.999 1.44 PRS_PLINK_1.99526231496888e.06 726 Peripheral enthesopathies and allied syndromes Both 10176 107805 14 musculoskeletal darkolivegreen 107805, 10176 26930, 2553 26999, 2533 27322, 2534 26525, 2553 0.00707 0.0104 0.494 0.306 1.01 0.987 1.03 -0.00954 0.0293 0.745 0.1279 0.991 0.935 1.05 -0.0213 0.0293 0.467 0.3305 0.979 0.924 1.04 0.0167 0.0293 0.57 0.2441 1.02 0.96 1.08 PRS_PLINK_1.99526231496888e.06 726.1 Enthesopathy Both 6550 69785 14 musculoskeletal darkolivegreen 69785, 6550 17460, 1641 17513, 1628 17525, 1636 17274, 1644 0.0121 0.0129 0.347 0.4591 1.01 0.987 1.04 -0.00923 0.0366 0.801 0.09643 0.991 0.922 1.06 -0.00569 0.0365 0.876 0.05733 0.994 0.926 1.07 0.015 0.0366 0.683 0.1659 1.02 0.945 1.09 PRS_PLINK_1.99526231496888e.06 726.2 Synoviopathy Both 266 2591 14 musculoskeletal darkolivegreen 2591, 266 653, 66 648, 83 644, 62 646, 55 -0.0898 0.0659 0.173 0.7621 0.914 0.803 1.04 0.225 0.173 0.194 0.7122 1.25 0.892 1.76 -0.0378 0.184 0.837 0.0772 0.963 0.671 1.38 -0.174 0.189 0.356 0.4482 0.84 0.58 1.22 PRS_PLINK_1.99526231496888e.06 726.3 Bursitis Both 564 6223 14 musculoskeletal darkolivegreen 6223, 564 1570, 128 1542, 155 1556, 146 1553, 135 -0.00447 0.0432 0.918 0.03737 0.996 0.915 1.08 0.201 0.124 0.105 0.9787 1.22 0.959 1.56 0.146 0.126 0.244 0.6121 1.16 0.905 1.48 0.0659 0.128 0.607 0.2171 1.07 0.831 1.37 PRS_PLINK_1.99526231496888e.06 727 Other disorders of synovium, tendon, and bursa Both 5229 54739 14 musculoskeletal darkolivegreen 54739, 5229 13685, 1330 13794, 1289 13651, 1299 13587, 1309 0.00747 0.0145 0.606 0.2175 1.01 0.979 1.04 -0.0384 0.0409 0.348 0.459 0.962 0.888 1.04 -0.0192 0.0408 0.639 0.1947 0.981 0.906 1.06 -0.00708 0.0408 0.862 0.06432 0.993 0.917 1.08 PRS_PLINK_1.99526231496888e.06 727.1 Synovitis and tenosynovitis Both 1873 20440 14 musculoskeletal darkolivegreen 20440, 1873 5103, 512 5185, 439 5098, 457 5047, 464 -0.015 0.0243 0.537 0.2701 0.985 0.939 1.03 -0.167 0.0679 0.0137 1.864 0.846 0.741 0.966 -0.111 0.0673 0.1 0.9982 0.895 0.785 1.02 -0.0828 0.0671 0.218 0.6625 0.921 0.807 1.05 PRS_PLINK_1.99526231496888e.06 727.2 Bursitis disorders Both 77 733 14 musculoskeletal darkolivegreen 733, 77 185, 16 182, 19 183, 26 183, 16 0.113 0.115 0.325 0.488 1.12 0.894 1.4 0.198 0.348 0.57 0.2439 1.22 0.616 2.41 0.501 0.325 0.123 0.9086 1.65 0.873 3.12 0.0976 0.359 0.786 0.1048 1.1 0.546 2.23 PRS_PLINK_1.99526231496888e.06 727.4 Ganglion and cyst of synovium, tendon, and bursa Both 2325 23560 14 musculoskeletal darkolivegreen 23560, 2325 5906, 596 5888, 578 5894, 581 5860, 569 -0.00294 0.0218 0.893 0.04916 0.997 0.955 1.04 -0.0281 0.0611 0.646 0.1895 0.972 0.863 1.1 -0.0221 0.0611 0.718 0.1438 0.978 0.868 1.1 -0.0367 0.0614 0.55 0.2594 0.964 0.855 1.09 PRS_PLINK_1.99526231496888e.06 727.5 Rupture of synovium Both 375 4137 14 musculoskeletal darkolivegreen 4137, 375 1042, 79 1029, 94 1049, 91 1017, 111 0.105 0.0518 0.0423 1.373 1.11 1 1.23 0.169 0.158 0.284 0.5466 1.18 0.869 1.61 0.13 0.159 0.411 0.3866 1.14 0.835 1.55 0.362 0.153 0.0179 1.747 1.44 1.06 1.94 PRS_PLINK_1.99526231496888e.06 727.6 Rupture of tendon, nontraumatic Both 242 2529 14 musculoskeletal darkolivegreen 2529, 242 634, 60 629, 57 637, 71 627, 54 -0.00433 0.0668 0.948 0.02305 0.996 0.873 1.14 -0.0454 0.191 0.812 0.0903 0.956 0.657 1.39 0.168 0.182 0.356 0.4483 1.18 0.828 1.69 -0.11 0.194 0.572 0.2426 0.896 0.613 1.31 PRS_PLINK_1.99526231496888e.06 727.7 Contracture of tendon (sheath) Both 99 1022 14 musculoskeletal darkolivegreen 1022, 99 261, 26 250, 22 257, 23 254, 28 -0.00288 0.106 0.978 0.009502 0.997 0.81 1.23 -0.13 0.295 0.66 0.1802 0.878 0.493 1.57 -0.0888 0.296 0.764 0.117 0.915 0.513 1.63 0.0894 0.28 0.75 0.1252 1.09 0.632 1.89 PRS_PLINK_1.99526231496888e.06 728 Disorders of muscle, ligament, and fascia Both 2465 24188 14 musculoskeletal darkolivegreen 24188, 2465 6068, 614 6029, 627 6038, 605 6044, 617 0.00205 0.0209 0.922 0.03536 1 0.962 1.04 0.0264 0.0596 0.658 0.1818 1.03 0.914 1.15 -0.0111 0.06 0.854 0.06868 0.989 0.879 1.11 0.00649 0.0598 0.914 0.03922 1.01 0.895 1.13 PRS_PLINK_1.99526231496888e.06 728.2 Laxity of ligament or hypermobility syndrome Both 308 3266 14 musculoskeletal darkolivegreen 3266, 308 820, 72 813, 66 818, 83 815, 87 0.101 0.0575 0.0781 1.108 1.11 0.989 1.24 -0.071 0.176 0.687 0.1628 0.932 0.659 1.32 0.131 0.168 0.436 0.3604 1.14 0.82 1.58 0.209 0.166 0.208 0.6813 1.23 0.89 1.71 PRS_PLINK_1.99526231496888e.06 728.7 Fasciitis Both 2559 25266 14 musculoskeletal darkolivegreen 25266, 2559 6316, 623 6320, 657 6315, 631 6307, 646 0.00804 0.0205 0.695 0.1582 1.01 0.968 1.05 0.0509 0.0587 0.385 0.4143 1.05 0.938 1.18 0.0101 0.0592 0.864 0.06352 1.01 0.9 1.13 0.0359 0.059 0.543 0.2651 1.04 0.923 1.16 PRS_PLINK_1.99526231496888e.06 728.71 Contracture of palmar fascia [Dupuytren's disease] Both 2348 22728 14 musculoskeletal darkolivegreen 22728, 2348 5681, 587 5713, 598 5660, 574 5666, 587 -0.00111 0.0214 0.959 0.01836 0.999 0.958 1.04 0.0126 0.061 0.837 0.07743 1.01 0.899 1.14 -0.0207 0.0616 0.736 0.133 0.979 0.868 1.11 0.000127 0.0613 0.998 0.0007165 1 0.887 1.13 PRS_PLINK_1.99526231496888e.06 729 Other disorders of soft tissues Both 3620 44027 14 musculoskeletal darkolivegreen 44027, 3620 11023, 871 11005, 866 11051, 930 10939, 952 0.037 0.0171 0.0307 1.513 1.04 1 1.07 -0.00276 0.0498 0.956 0.01962 0.997 0.904 1.1 0.0649 0.049 0.185 0.732 1.07 0.969 1.17 0.0986 0.0488 0.0436 1.361 1.1 1 1.21 PRS_PLINK_1.99526231496888e.06 729.1 Rheumatism, unspecified and fibrositis Both 655 7817 14 musculoskeletal darkolivegreen 7817, 655 1967, 170 1954, 157 1957, 159 1939, 169 0.0164 0.0409 0.689 0.1617 1.02 0.938 1.1 -0.0696 0.115 0.544 0.2642 0.933 0.745 1.17 -0.0592 0.114 0.605 0.218 0.943 0.753 1.18 0.00898 0.113 0.937 0.02846 1.01 0.809 1.26 PRS_PLINK_1.99526231496888e.06 729.3 Panniculitis Both 77 746 14 musculoskeletal darkolivegreen 746, 77 187, 13 187, 25 186, 23 186, 16 5.73e-06 0.119 1 1.665e-05 1 0.792 1.26 0.579 0.346 0.0936 1.029 1.78 0.907 3.51 0.541 0.35 0.122 0.9138 1.72 0.865 3.41 0.23 0.375 0.54 0.268 1.26 0.604 2.62 PRS_PLINK_1.99526231496888e.06 731 Osteitis deformans and osteopathies associated with other disorders classified elsewhere Both 196 2119 14 musculoskeletal darkolivegreen 2119, 196 532, 51 533, 48 526, 49 528, 48 -0.0108 0.076 0.887 0.05187 0.989 0.852 1.15 -0.0503 0.208 0.809 0.09221 0.951 0.633 1.43 -0.0345 0.207 0.868 0.06166 0.966 0.644 1.45 -0.0487 0.208 0.815 0.08911 0.952 0.634 1.43 PRS_PLINK_1.99526231496888e.06 731.1 Osteitis deformans [Paget's disease of bone] Both 186 2012 14 musculoskeletal darkolivegreen 2012, 186 520, 49 496, 43 495, 49 501, 45 -0.0145 0.0777 0.852 0.06942 0.986 0.846 1.15 -0.0773 0.215 0.72 0.1429 0.926 0.607 1.41 0.037 0.21 0.86 0.06557 1.04 0.688 1.56 -0.0367 0.213 0.863 0.06398 0.964 0.635 1.46 PRS_PLINK_1.99526231496888e.06 732 Osteochondropathies Both 344 3573 14 musculoskeletal darkolivegreen 3573, 344 893, 90 898, 89 900, 77 880, 88 -0.0354 0.0575 0.538 0.2689 0.965 0.862 1.08 -0.0198 0.156 0.899 0.04638 0.98 0.722 1.33 -0.167 0.161 0.299 0.5246 0.846 0.617 1.16 -0.0302 0.157 0.847 0.07224 0.97 0.714 1.32 PRS_PLINK_1.99526231496888e.06 732.1 Juvenile osteochondrosis Both 145 1541 14 musculoskeletal darkolivegreen 1541, 145 393, 40 377, 46 384, 27 385, 32 -0.132 0.0887 0.137 0.8644 0.876 0.736 1.04 0.167 0.225 0.457 0.3398 1.18 0.76 1.84 -0.354 0.255 0.166 0.7808 0.702 0.426 1.16 -0.24 0.244 0.326 0.4866 0.787 0.487 1.27 PRS_PLINK_1.99526231496888e.06 732.7 Osteochondritis dissecans Both 43 451 14 musculoskeletal darkolivegreen 451, 43 114, 11 112, 7 111, 12 113, 13 0.0577 0.153 0.707 0.1508 1.06 0.784 1.43 -0.385 0.467 0.41 0.3875 0.681 0.273 1.7 0.0836 0.415 0.84 0.07547 1.09 0.482 2.45 0.151 0.413 0.715 0.146 1.16 0.518 2.61 PRS_PLINK_1.99526231496888e.06 733 Other disorders of bone and cartilage Both 1196 13157 14 musculoskeletal darkolivegreen 13157, 1196 3288, 302 3289, 287 3320, 296 3258, 311 0.00917 0.0304 0.763 0.1176 1.01 0.951 1.07 -0.0506 0.0859 0.556 0.2551 0.951 0.803 1.12 -0.0253 0.0853 0.767 0.1153 0.975 0.825 1.15 0.0417 0.0844 0.622 0.2065 1.04 0.884 1.23 PRS_PLINK_1.99526231496888e.06 733.2 Cyst of bone Both 225 2302 14 musculoskeletal darkolivegreen 2302, 225 590, 55 561, 56 577, 54 574, 60 0.00475 0.0707 0.946 0.0239 1 0.875 1.15 0.078 0.197 0.692 0.1597 1.08 0.735 1.59 -0.0146 0.198 0.941 0.02632 0.985 0.668 1.45 0.113 0.194 0.56 0.2515 1.12 0.766 1.64 PRS_PLINK_1.99526231496888e.06 733.4 Aseptic necrosis of bone Both 316 3935 14 musculoskeletal darkolivegreen 3935, 316 997, 79 970, 64 984, 89 982, 84 0.0446 0.0578 0.441 0.356 1.05 0.934 1.17 -0.178 0.173 0.301 0.5209 0.837 0.597 1.17 0.134 0.16 0.401 0.3966 1.14 0.836 1.56 0.0623 0.162 0.701 0.1546 1.06 0.775 1.46 PRS_PLINK_1.99526231496888e.06 733.6 Costochondritis Both 85 939 14 musculoskeletal darkolivegreen 939, 85 237, 24 238, 12 234, 27 230, 22 0.0588 0.105 0.574 0.2412 1.06 0.864 1.3 -0.709 0.352 0.0439 1.358 0.492 0.247 0.981 0.113 0.289 0.696 0.1571 1.12 0.635 1.97 -0.0741 0.303 0.806 0.09345 0.929 0.513 1.68 PRS_PLINK_1.99526231496888e.06 733.8 Malunion and nonunion of fracture Both 820 9217 14 musculoskeletal darkolivegreen 9217, 820 2325, 203 2281, 195 2306, 217 2301, 205 -0.00798 0.0371 0.83 0.08103 0.992 0.922 1.07 -0.0154 0.104 0.882 0.05435 0.985 0.803 1.21 0.0761 0.102 0.454 0.3427 1.08 0.884 1.32 0.031 0.103 0.764 0.1168 1.03 0.843 1.26 PRS_PLINK_1.99526231496888e.06 733.9 Chondromalacia Both 93 930 14 musculoskeletal darkolivegreen 930, 93 234, 30 231, 29 233, 14 232, 20 -0.204 0.112 0.0695 1.158 0.815 0.654 1.02 0.0222 0.275 0.936 0.02887 1.02 0.596 1.75 -0.726 0.326 0.0259 1.587 0.484 0.256 0.916 -0.419 0.298 0.16 0.7971 0.658 0.367 1.18 PRS_PLINK_1.99526231496888e.06 735 Acquired foot deformities Both 6982 71984 14 musculoskeletal darkolivegreen 71984, 6982 17987, 1690 18039, 1766 18200, 1762 17743, 1763 0.00705 0.0125 0.574 0.2413 1.01 0.983 1.03 0.0416 0.0356 0.243 0.6143 1.04 0.972 1.12 0.0317 0.0356 0.373 0.4282 1.03 0.963 1.11 0.0572 0.0357 0.109 0.9631 1.06 0.987 1.14 PRS_PLINK_1.99526231496888e.06 735.1 Flat foot Both 122 1423 14 musculoskeletal darkolivegreen 1423, 122 358, 23 355, 28 354, 43 356, 28 0.0464 0.0913 0.611 0.2139 1.05 0.876 1.25 0.196 0.283 0.487 0.3123 1.22 0.699 2.12 0.661 0.264 0.0124 1.906 1.94 1.15 3.25 0.229 0.285 0.422 0.375 1.26 0.719 2.2 PRS_PLINK_1.99526231496888e.06 735.2 Acquired toe deformities Both 3551 37254 14 musculoskeletal darkolivegreen 37254, 3551 9366, 868 9272, 878 9327, 878 9282, 926 0.0171 0.0175 0.329 0.4833 1.02 0.983 1.05 0.022 0.05 0.661 0.18 1.02 0.927 1.13 0.018 0.05 0.719 0.1433 1.02 0.923 1.12 0.0758 0.0495 0.125 0.9019 1.08 0.979 1.19 PRS_PLINK_1.99526231496888e.06 735.21 Hammer toe (acquired) Both 1329 14089 14 musculoskeletal darkolivegreen 14089, 1329 3531, 325 3551, 309 3491, 329 3514, 365 0.0428 0.0284 0.132 0.8809 1.04 0.987 1.1 -0.0533 0.0828 0.52 0.284 0.948 0.806 1.12 0.0251 0.0817 0.759 0.1198 1.03 0.874 1.2 0.121 0.0798 0.129 0.89 1.13 0.965 1.32 PRS_PLINK_1.99526231496888e.06 735.23 Hallux rigidus Both 1142 11378 14 musculoskeletal darkolivegreen 11378, 1142 2860, 278 2828, 292 2853, 282 2834, 290 -0.00275 0.031 0.929 0.03181 0.997 0.938 1.06 0.0589 0.0877 0.502 0.2995 1.06 0.893 1.26 0.022 0.0885 0.804 0.09484 1.02 0.859 1.22 0.0512 0.0879 0.56 0.2516 1.05 0.886 1.25 PRS_PLINK_1.99526231496888e.06 735.3 Hallux valgus (Bunion) Both 4947 50311 14 musculoskeletal darkolivegreen 50311, 4947 12656, 1208 12585, 1262 12490, 1206 12567, 1270 0.008 0.0149 0.591 0.2281 1.01 0.979 1.04 0.0499 0.0422 0.237 0.6256 1.05 0.968 1.14 0.0141 0.0426 0.741 0.1301 1.01 0.933 1.1 0.0568 0.0422 0.178 0.7503 1.06 0.975 1.15 PRS_PLINK_1.99526231496888e.06 736 Other acquired deformities of limbs Both 1006 11671 14 musculoskeletal darkolivegreen 11671, 1006 2927, 236 2927, 271 2940, 238 2872, 261 0.021 0.0326 0.52 0.2838 1.02 0.958 1.09 0.141 0.0926 0.129 0.8909 1.15 0.96 1.38 0.0156 0.0954 0.87 0.06026 1.02 0.843 1.22 0.118 0.0935 0.209 0.6804 1.12 0.936 1.35 PRS_PLINK_1.99526231496888e.06 736.2 Acquired deformities of finger Both 171 1820 14 musculoskeletal darkolivegreen 1820, 171 466, 42 444, 43 455, 39 455, 47 0.0343 0.0804 0.67 0.174 1.03 0.884 1.21 0.0763 0.223 0.733 0.135 1.08 0.696 1.67 -0.04 0.229 0.861 0.06491 0.961 0.614 1.5 0.13 0.22 0.553 0.2572 1.14 0.74 1.75 PRS_PLINK_1.99526231496888e.06 737 Curvature of spine Both 691 8211 14 musculoskeletal darkolivegreen 8211, 691 2052, 190 2056, 153 2048, 180 2052, 168 -0.0208 0.0398 0.602 0.2204 0.979 0.906 1.06 -0.219 0.113 0.0522 1.282 0.804 0.644 1 -0.0463 0.108 0.669 0.1747 0.955 0.772 1.18 -0.111 0.11 0.316 0.5003 0.895 0.721 1.11 PRS_PLINK_1.99526231496888e.06 737.3 Kyphoscoliosis and scoliosis Both 649 7702 14 musculoskeletal darkolivegreen 7702, 649 1924, 178 1924, 144 1957, 172 1894, 155 -0.0212 0.0412 0.608 0.2163 0.979 0.903 1.06 -0.213 0.116 0.0665 1.177 0.808 0.643 1.01 -0.0461 0.111 0.678 0.1686 0.955 0.768 1.19 -0.11 0.114 0.337 0.4719 0.896 0.716 1.12 PRS_PLINK_1.99526231496888e.06 738 Other acquired musculoskeletal deformity Both 1249 13821 14 musculoskeletal darkolivegreen 13821, 1249 3477, 309 3439, 321 3449, 304 3454, 314 0.00169 0.0296 0.954 0.02024 1 0.945 1.06 0.0489 0.0831 0.556 0.2547 1.05 0.892 1.24 -0.00737 0.0841 0.93 0.03142 0.993 0.842 1.17 0.0274 0.0836 0.743 0.1289 1.03 0.872 1.21 PRS_PLINK_1.99526231496888e.06 738.4 Acquired spondylolisthesis Both 955 10770 14 musculoskeletal darkolivegreen 10770, 955 2701, 248 2689, 252 2693, 227 2685, 227 -0.0512 0.0343 0.135 0.8689 0.95 0.888 1.02 0.0191 0.0933 0.838 0.07668 1.02 0.849 1.22 -0.0867 0.0956 0.365 0.4379 0.917 0.76 1.11 -0.0788 0.0957 0.41 0.3868 0.924 0.766 1.11 PRS_PLINK_1.99526231496888e.06 739 Contracture of joint Both 306 3667 14 musculoskeletal darkolivegreen 3667, 306 921, 64 910, 85 916, 76 917, 81 0.0259 0.0583 0.658 0.1821 1.03 0.915 1.15 0.3 0.17 0.0782 1.107 1.35 0.967 1.88 0.186 0.175 0.288 0.5412 1.2 0.855 1.7 0.269 0.173 0.119 0.9259 1.31 0.933 1.84 PRS_PLINK_1.99526231496888e.06 740 Osteoarthrosis Both 17376 166682 14 musculoskeletal darkolivegreen 166682, 17376 41704, 4139 41679, 4251 41703, 4454 41547, 4524 0.033 0.00788 2.79e-05 4.555 1.03 1.02 1.05 0.0236 0.0229 0.303 0.5182 1.02 0.979 1.07 0.0661 0.0227 0.00359 2.445 1.07 1.02 1.12 0.0786 0.0227 0.000525 3.28 1.08 1.03 1.13 PRS_PLINK_1.99526231496888e.06 740.1 Osteoarthritis; localized Both 11040 119049 14 musculoskeletal darkolivegreen 119049, 11040 29895, 2675 29895, 2692 29565, 2824 29652, 2843 0.0294 0.00983 0.00276 2.559 1.03 1.01 1.05 0.00571 0.0285 0.841 0.07506 1.01 0.951 1.06 0.0647 0.0282 0.0217 1.663 1.07 1.01 1.13 0.0667 0.0282 0.0181 1.743 1.07 1.01 1.13 PRS_PLINK_1.99526231496888e.06 740.11 Osteoarthrosis, localized, primary Both 5522 62406 14 musculoskeletal darkolivegreen 62406, 5522 15658, 1367 15534, 1313 15597, 1430 15593, 1409 0.0283 0.0139 0.0419 1.378 1.03 1 1.06 -0.0312 0.0403 0.438 0.3588 0.969 0.896 1.05 0.0513 0.0395 0.194 0.7124 1.05 0.974 1.14 0.0368 0.0397 0.353 0.4516 1.04 0.96 1.12 PRS_PLINK_1.99526231496888e.06 740.12 Osteoarthrosis, localized, secondary Both 227 2490 14 musculoskeletal darkolivegreen 2490, 227 637, 62 613, 51 621, 64 619, 50 0.00304 0.0674 0.964 0.01593 1 0.879 1.14 -0.138 0.196 0.481 0.3179 0.871 0.594 1.28 0.0599 0.185 0.746 0.1271 1.06 0.739 1.53 -0.172 0.196 0.382 0.4175 0.842 0.573 1.24 PRS_PLINK_1.99526231496888e.06 740.2 Osteoarthrosis, generalized Both 343 4215 14 musculoskeletal darkolivegreen 4215, 343 1053, 83 1057, 93 1052, 77 1052, 90 0.0266 0.0558 0.634 0.1982 1.03 0.921 1.15 0.116 0.156 0.457 0.3397 1.12 0.827 1.52 -0.0884 0.163 0.588 0.2308 0.915 0.665 1.26 0.0737 0.157 0.639 0.1945 1.08 0.791 1.46 PRS_PLINK_1.99526231496888e.06 740.9 Osteoarthrosis NOS Both 7456 87250 14 musculoskeletal darkolivegreen 87250, 7456 21865, 1752 21736, 1833 21876, 1935 21749, 1934 0.0417 0.0119 0.000445 3.352 1.04 1.02 1.07 0.0517 0.0347 0.136 0.8651 1.05 0.984 1.13 0.0997 0.0343 0.00369 2.432 1.1 1.03 1.18 0.104 0.0344 0.00239 2.621 1.11 1.04 1.19 PRS_PLINK_1.99526231496888e.06 741 Symptoms and disorders of the joints Both 2324 25926 14 musculoskeletal darkolivegreen 25926, 2324 6492, 576 6506, 527 6519, 607 6402, 614 0.0496 0.0215 0.0209 1.68 1.05 1.01 1.1 -0.0905 0.0627 0.149 0.8268 0.913 0.808 1.03 0.0469 0.0607 0.44 0.3563 1.05 0.93 1.18 0.0823 0.0606 0.174 0.7584 1.09 0.964 1.22 PRS_PLINK_1.99526231496888e.06 741.1 Ankylosis of joint Both 68 725 14 musculoskeletal darkolivegreen 725, 68 182, 14 181, 17 181, 16 181, 21 0.2 0.125 0.109 0.962 1.22 0.956 1.56 0.171 0.363 0.638 0.1952 1.19 0.583 2.41 0.0572 0.367 0.876 0.05744 1.06 0.516 2.17 0.411 0.348 0.237 0.6253 1.51 0.763 2.98 PRS_PLINK_1.99526231496888e.06 741.2 Stiffness of joint Both 450 4582 14 musculoskeletal darkolivegreen 4582, 450 1156, 99 1134, 100 1157, 132 1132, 119 0.0794 0.0483 0.1 0.9998 1.08 0.985 1.19 0.0172 0.147 0.907 0.04243 1.02 0.763 1.36 0.28 0.139 0.0438 1.358 1.32 1.01 1.74 0.215 0.142 0.13 0.8866 1.24 0.939 1.64 PRS_PLINK_1.99526231496888e.06 741.3 Difficulty in walking Both 79 1092 14 musculoskeletal darkolivegreen 1092, 79 276, 22 271, 16 272, 14 273, 27 0.0965 0.111 0.383 0.4168 1.1 0.887 1.37 -0.308 0.329 0.35 0.4562 0.735 0.385 1.4 -0.429 0.339 0.205 0.6878 0.651 0.335 1.26 0.195 0.292 0.505 0.297 1.22 0.685 2.15 PRS_PLINK_1.99526231496888e.06 741.4 Joint effusions Both 843 10050 14 musculoskeletal darkolivegreen 10050, 843 2523, 220 2510, 172 2533, 224 2481, 227 0.055 0.0355 0.122 0.9154 1.06 0.985 1.13 -0.24 0.105 0.0229 1.641 0.787 0.64 0.967 0.0179 0.0989 0.857 0.06726 1.02 0.839 1.24 0.0556 0.0986 0.573 0.2419 1.06 0.871 1.28 PRS_PLINK_1.99526231496888e.06 741.5 Hemarthrosis Both 68 795 14 musculoskeletal darkolivegreen 795, 68 208, 11 190, 17 198, 18 199, 22 0.251 0.121 0.0385 1.415 1.29 1.01 1.63 0.554 0.382 0.147 0.8332 1.74 0.823 3.68 0.558 0.378 0.14 0.8549 1.75 0.833 3.66 0.765 0.369 0.0383 1.417 2.15 1.04 4.43 PRS_PLINK_1.99526231496888e.06 741.6 Villonodular synovitis Both 37 413 14 musculoskeletal darkolivegreen 413, 37 105, 12 103, 10 103, 9 102, 6 -0.143 0.169 0.396 0.4023 0.867 0.623 1.21 -0.207 0.43 0.63 0.2005 0.813 0.35 1.89 -0.243 0.437 0.578 0.238 0.784 0.333 1.85 -0.58 0.494 0.241 0.6184 0.56 0.213 1.48 PRS_PLINK_1.99526231496888e.06 742 Derangement of joint, non-traumatic Both 2079 21769 14 musculoskeletal darkolivegreen 21769, 2079 5470, 495 5418, 511 5477, 524 5396, 549 0.0386 0.0229 0.092 1.036 1.04 0.994 1.09 0.0397 0.0658 0.547 0.2621 1.04 0.915 1.18 0.0557 0.0655 0.395 0.4038 1.06 0.93 1.2 0.112 0.0649 0.0843 1.074 1.12 0.985 1.27 PRS_PLINK_1.99526231496888e.06 742.1 Loose body in joint Both 236 2417 14 musculoskeletal darkolivegreen 2417, 236 616, 46 594, 54 603, 67 603, 69 0.139 0.0663 0.0362 1.441 1.15 1.01 1.31 0.199 0.206 0.333 0.4775 1.22 0.815 1.83 0.38 0.198 0.055 1.26 1.46 0.992 2.15 0.426 0.198 0.0314 1.503 1.53 1.04 2.26 PRS_PLINK_1.99526231496888e.06 742.2 Pathological, developmental or recurrent dislocation Both 75 790 14 musculoskeletal darkolivegreen 790, 75 203, 21 193, 16 196, 22 198, 16 -0.0419 0.12 0.727 0.1385 0.959 0.758 1.21 -0.191 0.334 0.567 0.2466 0.826 0.43 1.59 0.0791 0.313 0.8 0.09671 1.08 0.586 2 -0.245 0.336 0.465 0.3326 0.783 0.405 1.51 PRS_PLINK_1.99526231496888e.06 742.8 Articular cartilage disorder Both 350 3839 14 musculoskeletal darkolivegreen 3839, 350 961, 73 961, 79 957, 90 958, 108 0.13 0.0555 0.0187 1.728 1.14 1.02 1.27 0.0725 0.167 0.665 0.1773 1.08 0.775 1.49 0.223 0.163 0.17 0.7687 1.25 0.909 1.72 0.384 0.158 0.0148 1.83 1.47 1.08 2 PRS_PLINK_1.99526231496888e.06 742.9 Other derangement of joint Both 1489 15364 14 musculoskeletal darkolivegreen 15364, 1489 3853, 374 3826, 376 3886, 364 3796, 375 0.0111 0.0273 0.685 0.1641 1.01 0.958 1.07 0.0117 0.0764 0.878 0.05626 1.01 0.871 1.18 -0.0335 0.077 0.663 0.1782 0.967 0.832 1.12 0.0118 0.0767 0.878 0.05667 1.01 0.871 1.18 PRS_PLINK_1.99526231496888e.06 743 Osteoporosis, osteopenia and pathological fracture Both 4923 54050 14 musculoskeletal darkolivegreen 54050, 4923 13554, 1198 13479, 1212 13497, 1279 13501, 1234 0.021 0.0148 0.156 0.807 1.02 0.992 1.05 0.0162 0.0425 0.703 0.153 1.02 0.935 1.1 0.0681 0.042 0.105 0.9787 1.07 0.986 1.16 0.0345 0.0424 0.415 0.3817 1.04 0.953 1.12 PRS_PLINK_1.99526231496888e.06 743.1 Osteoporosis Both 4147 45488 14 musculoskeletal darkolivegreen 45488, 4147 11390, 1000 11385, 1049 11351, 1066 11348, 1032 0.0138 0.0161 0.392 0.407 1.01 0.982 1.05 0.0474 0.0461 0.304 0.5178 1.05 0.958 1.15 0.0635 0.046 0.167 0.7767 1.07 0.974 1.17 0.0341 0.0463 0.461 0.3359 1.03 0.945 1.13 PRS_PLINK_1.99526231496888e.06 743.11 Osteoporosis NOS Both 3611 39824 14 musculoskeletal darkolivegreen 39824, 3611 9944, 872 9987, 911 9928, 925 9953, 903 0.0125 0.0173 0.471 0.3272 1.01 0.979 1.05 0.039 0.0494 0.43 0.3664 1.04 0.944 1.15 0.0577 0.0493 0.242 0.6171 1.06 0.962 1.17 0.0341 0.0496 0.491 0.309 1.03 0.939 1.14 PRS_PLINK_1.99526231496888e.06 743.13 Other specified osteoporosis Both 319 3471 14 musculoskeletal darkolivegreen 3471, 319 888, 73 853, 82 861, 91 868, 73 0.0281 0.0568 0.622 0.2066 1.03 0.92 1.15 0.159 0.167 0.341 0.4673 1.17 0.845 1.62 0.245 0.163 0.133 0.8777 1.28 0.928 1.76 0.0266 0.171 0.877 0.05717 1.03 0.734 1.44 PRS_PLINK_1.99526231496888e.06 743.2 Pathologic fracture Both 281 3692 14 musculoskeletal darkolivegreen 3692, 281 923, 69 920, 65 922, 80 923, 67 0.00416 0.0623 0.947 0.02374 1 0.889 1.13 -0.0621 0.177 0.726 0.1389 0.94 0.664 1.33 0.178 0.17 0.293 0.5338 1.2 0.857 1.67 -0.0125 0.177 0.944 0.02524 0.988 0.698 1.4 PRS_PLINK_1.99526231496888e.06 743.9 Osteopenia or other disorder of bone and cartilage Both 583 6068 14 musculoskeletal darkolivegreen 6068, 583 1524, 147 1515, 121 1514, 148 1512, 167 0.0857 0.0425 0.0438 1.358 1.09 1 1.18 -0.189 0.127 0.138 0.8597 0.828 0.645 1.06 0.0168 0.121 0.89 0.05058 1.02 0.801 1.29 0.139 0.118 0.241 0.6182 1.15 0.911 1.45 PRS_PLINK_1.99526231496888e.06 745 Pain in joint Both 5204 58798 14 musculoskeletal darkolivegreen 58798, 5204 14698, 1291 14709, 1280 14794, 1342 14578, 1291 0.00901 0.0145 0.533 0.2731 1.01 0.981 1.04 -0.00814 0.0411 0.843 0.07409 0.992 0.915 1.08 0.033 0.0407 0.417 0.3803 1.03 0.954 1.12 0.0112 0.0411 0.786 0.1047 1.01 0.933 1.1 PRS_PLINK_1.99526231496888e.06 747 Cardiac and circulatory congenital anomalies Both 1632 19231 15 congenital anomalies mediumspringgreen 19231, 1632 4818, 425 4829, 406 4782, 408 4796, 392 -0.0176 0.0258 0.495 0.3054 0.983 0.934 1.03 -0.046 0.0722 0.524 0.2803 0.955 0.829 1.1 -0.0307 0.0722 0.67 0.1737 0.97 0.842 1.12 -0.0661 0.073 0.365 0.4377 0.936 0.811 1.08 PRS_PLINK_1.99526231496888e.06 747.1 Cardiac congenital anomalies Both 1509 17983 15 congenital anomalies mediumspringgreen 17983, 1509 4496, 392 4505, 370 4480, 390 4496, 356 -0.0209 0.0269 0.436 0.3605 0.979 0.929 1.03 -0.0589 0.0754 0.435 0.3618 0.943 0.813 1.09 0.000972 0.0745 0.99 0.004547 1 0.865 1.16 -0.0875 0.0762 0.251 0.6004 0.916 0.789 1.06 PRS_PLINK_1.99526231496888e.06 747.11 Cardiac shunt/ heart septal defect Both 413 4430 15 congenital anomalies mediumspringgreen 4430, 413 1106, 105 1107, 115 1122, 106 1092, 86 -0.0515 0.0532 0.332 0.4786 0.95 0.856 1.05 0.0966 0.141 0.493 0.3075 1.1 0.836 1.45 -0.00335 0.143 0.981 0.008177 0.997 0.753 1.32 -0.164 0.151 0.277 0.5578 0.849 0.631 1.14 PRS_PLINK_1.99526231496888e.06 747.12 Valvular heart disease/ heart chambers Both 152 1731 15 congenital anomalies mediumspringgreen 1731, 152 435, 47 431, 35 433, 39 432, 31 -0.122 0.0875 0.162 0.7911 0.885 0.745 1.05 -0.276 0.23 0.23 0.6388 0.759 0.483 1.19 -0.174 0.224 0.438 0.3587 0.84 0.542 1.3 -0.379 0.238 0.111 0.9531 0.684 0.429 1.09 PRS_PLINK_1.99526231496888e.06 747.13 Congenital anomalies of great vessels Both 929 11802 15 congenital anomalies mediumspringgreen 11802, 929 2972, 239 2928, 215 2948, 241 2951, 234 -0.00759 0.0337 0.822 0.0852 0.992 0.929 1.06 -0.0942 0.0973 0.333 0.4775 0.91 0.752 1.1 0.014 0.0947 0.883 0.05415 1.01 0.842 1.22 -0.015 0.0955 0.875 0.0578 0.985 0.817 1.19 PRS_PLINK_1.99526231496888e.06 747.2 Congenital anomalies of peripheral vascular system Both 116 1230 15 congenital anomalies mediumspringgreen 1230, 116 311, 31 304, 32 308, 20 307, 33 0.0296 0.0921 0.748 0.1261 1.03 0.86 1.23 0.0338 0.262 0.897 0.0471 1.03 0.62 1.73 -0.412 0.291 0.156 0.8065 0.662 0.375 1.17 0.0909 0.258 0.724 0.1401 1.1 0.661 1.82 PRS_PLINK_1.99526231496888e.06 748 Anomalies of respiratory system, congenital Both 35 360 15 congenital anomalies mediumspringgreen 360, 35 90, 5 91, 7 90, 10 89, 13 0.283 0.165 0.087 1.061 1.33 0.96 1.83 0.441 0.553 0.425 0.3713 1.55 0.526 4.59 0.64 0.519 0.217 0.6628 1.9 0.686 5.24 0.916 0.514 0.0751 1.124 2.5 0.912 6.85 PRS_PLINK_1.99526231496888e.06 749 Congenital anomalies of face and neck Both 226 2300 15 congenital anomalies mediumspringgreen 2300, 226 579, 46 570, 51 575, 58 575, 71 0.165 0.0688 0.0164 1.784 1.18 1.03 1.35 0.11 0.209 0.598 0.2234 1.12 0.741 1.68 0.247 0.204 0.227 0.6435 1.28 0.857 1.91 0.452 0.198 0.0226 1.646 1.57 1.07 2.32 PRS_PLINK_1.99526231496888e.06 750 Digestive congenital anomalies Both 420 4857 15 congenital anomalies mediumspringgreen 4857, 420 1216, 107 1215, 105 1216, 113 1207, 95 -0.0121 0.0503 0.81 0.09155 0.988 0.895 1.09 -0.00632 0.143 0.965 0.01562 0.994 0.751 1.31 0.0631 0.14 0.653 0.1852 1.07 0.809 1.4 -0.116 0.146 0.426 0.3711 0.89 0.669 1.19 PRS_PLINK_1.99526231496888e.06 750.1 Upper gastrointestinal congenital anomalies Both 206 2222 15 congenital anomalies mediumspringgreen 2222, 206 557, 55 552, 46 561, 60 550, 45 -0.00252 0.0707 0.972 0.01253 0.997 0.868 1.15 -0.155 0.207 0.452 0.3444 0.856 0.571 1.28 0.102 0.195 0.602 0.2208 1.11 0.755 1.62 -0.181 0.208 0.385 0.415 0.835 0.555 1.25 PRS_PLINK_1.99526231496888e.06 750.13 Congenital anomalies of mouth/tongue Both 122 1296 15 congenital anomalies mediumspringgreen 1296, 122 322, 35 324, 29 331, 38 317, 20 -0.105 0.0954 0.269 0.5705 0.9 0.746 1.08 -0.194 0.259 0.454 0.3432 0.824 0.496 1.37 0.0697 0.244 0.775 0.1106 1.07 0.664 1.73 -0.507 0.283 0.0737 1.133 0.602 0.346 1.05 PRS_PLINK_1.99526231496888e.06 750.2 Lower gastrointestinal congenital anomalies Both 210 2597 15 congenital anomalies mediumspringgreen 2597, 210 662, 53 638, 51 652, 54 645, 52 0.0185 0.071 0.795 0.09986 1.02 0.886 1.17 0.0119 0.201 0.953 0.02103 1.01 0.682 1.5 0.0373 0.199 0.851 0.0699 1.04 0.703 1.53 0.0064 0.2 0.974 0.01122 1.01 0.68 1.49 PRS_PLINK_1.99526231496888e.06 750.21 Congenital anomalies of intestine Both 158 1622 15 congenital anomalies mediumspringgreen 1622, 158 407, 36 404, 43 408, 43 403, 36 -0.00333 0.0817 0.967 0.01435 0.997 0.849 1.17 0.218 0.233 0.35 0.4559 1.24 0.787 1.97 0.187 0.233 0.422 0.3746 1.21 0.763 1.91 0.00583 0.242 0.981 0.008438 1.01 0.626 1.62 PRS_PLINK_1.99526231496888e.06 750.22 Congenital anomaly of gallbladder, bile ducts, liver, pancreas Both 46 877 15 congenital anomalies mediumspringgreen 877, 46 224, 11 216, 11 223, 13 214, 11 -0.0715 0.148 0.629 0.2013 0.931 0.696 1.24 0.00972 0.408 0.981 0.008343 1.01 0.454 2.25 0.164 0.397 0.68 0.1675 1.18 0.541 2.56 0.0171 0.406 0.966 0.01487 1.02 0.459 2.26 PRS_PLINK_1.99526231496888e.06 751 Genitourinary congenital anomalies Both 905 11418 15 congenital anomalies mediumspringgreen 11418, 905 2852, 233 2858, 227 2878, 237 2827, 208 -0.0311 0.0353 0.378 0.4229 0.969 0.905 1.04 -0.0264 0.0966 0.785 0.1053 0.974 0.806 1.18 0.00974 0.0958 0.919 0.03671 1.01 0.837 1.22 -0.0985 0.0989 0.319 0.4962 0.906 0.746 1.1 PRS_PLINK_1.99526231496888e.06 751.1 Congenital anomalies of genital organs Both 537 5406 15 congenital anomalies mediumspringgreen 5406, 537 1352, 130 1350, 154 1351, 141 1352, 112 -0.0797 0.047 0.0899 1.046 0.923 0.842 1.01 0.173 0.125 0.165 0.7815 1.19 0.931 1.52 0.0763 0.127 0.548 0.261 1.08 0.841 1.38 -0.161 0.134 0.229 0.6399 0.851 0.654 1.11 PRS_PLINK_1.99526231496888e.06 751.11 Congenital anomalies of female genital organs Female 372 3782 15 congenital anomalies mediumspringgreen 3782, 372 950, 83 940, 104 947, 100 944, 85 -0.0248 0.056 0.657 0.1823 0.975 0.874 1.09 0.236 0.153 0.124 0.9052 1.27 0.937 1.71 0.19 0.155 0.219 0.6597 1.21 0.893 1.64 0.0182 0.161 0.91 0.04099 1.02 0.743 1.39 PRS_PLINK_1.99526231496888e.06 751.12 Congenital anomalies of male genital organs Male 155 1519 15 congenital anomalies mediumspringgreen 1519, 155 379, 43 380, 42 382, 46 377, 24 -0.154 0.0861 0.0733 1.135 0.857 0.724 1.01 -0.0236 0.227 0.917 0.03746 0.977 0.626 1.52 0.055 0.221 0.804 0.09498 1.06 0.685 1.63 -0.589 0.26 0.0236 1.627 0.555 0.333 0.924 PRS_PLINK_1.99526231496888e.06 751.2 Congenital anomalies of urinary system Both 370 6043 15 congenital anomalies mediumspringgreen 6043, 370 1509, 99 1510, 81 1534, 93 1487, 97 0.037 0.0528 0.483 0.3157 1.04 0.936 1.15 -0.197 0.153 0.196 0.7077 0.821 0.609 1.11 -0.0732 0.148 0.621 0.2072 0.929 0.696 1.24 0.000331 0.147 0.998 0.0007817 1 0.75 1.33 PRS_PLINK_1.99526231496888e.06 751.21 Cystic kidney disease Both 133 3003 15 congenital anomalies mediumspringgreen 3003, 133 752, 35 751, 24 754, 26 745, 48 0.207 0.0837 0.0133 1.878 1.23 1.04 1.45 -0.355 0.262 0.176 0.7554 0.701 0.42 1.17 -0.28 0.257 0.276 0.5589 0.756 0.457 1.25 0.319 0.224 0.155 0.8103 1.38 0.887 2.13 PRS_PLINK_1.99526231496888e.06 751.22 Other specified congenital anomalies of kidney Both 186 2457 15 congenital anomalies mediumspringgreen 2457, 186 620, 54 613, 41 614, 47 610, 44 -0.0178 0.0748 0.812 0.09049 0.982 0.848 1.14 -0.258 0.212 0.223 0.6524 0.773 0.51 1.17 -0.119 0.205 0.561 0.2513 0.888 0.594 1.33 -0.166 0.209 0.426 0.3705 0.847 0.563 1.27 PRS_PLINK_1.99526231496888e.06 752 Nervous system congenital anomalies Both 231 2580 15 congenital anomalies mediumspringgreen 2580, 231 660, 68 633, 60 647, 48 640, 55 -0.0746 0.0703 0.289 0.5394 0.928 0.809 1.07 -0.0886 0.184 0.631 0.2003 0.915 0.638 1.31 -0.332 0.194 0.0869 1.061 0.717 0.49 1.05 -0.181 0.188 0.336 0.4734 0.834 0.577 1.21 PRS_PLINK_1.99526231496888e.06 752.1 Neural tube defects Both 180 2025 15 congenital anomalies mediumspringgreen 2025, 180 516, 45 498, 44 505, 41 506, 50 0.0494 0.0783 0.528 0.2771 1.05 0.901 1.23 -0.00894 0.219 0.967 0.01435 0.991 0.645 1.52 -0.0743 0.221 0.737 0.1326 0.928 0.602 1.43 0.116 0.213 0.585 0.2327 1.12 0.74 1.7 PRS_PLINK_1.99526231496888e.06 752.11 Spina bifida Both 145 1665 15 congenital anomalies mediumspringgreen 1665, 145 421, 38 415, 41 413, 31 416, 35 -0.000734 0.0881 0.993 0.002899 0.999 0.841 1.19 0.0695 0.233 0.765 0.1161 1.07 0.679 1.69 -0.183 0.246 0.459 0.3386 0.833 0.514 1.35 -0.0793 0.24 0.741 0.13 0.924 0.577 1.48 PRS_PLINK_1.99526231496888e.06 752.2 Other specified congenital anomalies of nervous system Both 54 593 15 congenital anomalies mediumspringgreen 593, 54 149, 20 147, 16 148, 11 148, 7 -0.367 0.16 0.0217 1.664 0.693 0.506 0.948 -0.169 0.348 0.627 0.2029 0.844 0.427 1.67 -0.572 0.378 0.13 0.8864 0.564 0.269 1.18 -0.971 0.427 0.0231 1.636 0.379 0.164 0.875 PRS_PLINK_1.99526231496888e.06 753 Congenital anomalies of the eye Both 81 953 15 congenital anomalies mediumspringgreen 953, 81 244, 22 234, 20 237, 17 238, 22 0.0799 0.115 0.486 0.3136 1.08 0.865 1.36 -0.0518 0.314 0.869 0.06102 0.95 0.513 1.76 -0.166 0.328 0.613 0.2126 0.847 0.446 1.61 0.0393 0.308 0.899 0.04648 1.04 0.569 1.9 PRS_PLINK_1.99526231496888e.06 753.1 Congenital cataract and lens anomalies Both 47 581 15 congenital anomalies mediumspringgreen 581, 47 146, 13 146, 13 147, 9 142, 12 0.0246 0.148 0.868 0.06136 1.02 0.766 1.37 0.00108 0.391 0.998 0.0009562 1 0.465 2.15 -0.33 0.423 0.435 0.3616 0.719 0.314 1.65 -0.058 0.397 0.884 0.05364 0.944 0.433 2.05 PRS_PLINK_1.99526231496888e.06 754 Congenital musculoskeletal deformities of spine Both 72 859 15 congenital anomalies mediumspringgreen 859, 72 220, 16 210, 20 214, 21 215, 15 -0.058 0.121 0.63 0.2004 0.944 0.745 1.2 0.263 0.338 0.436 0.3609 1.3 0.671 2.52 0.287 0.334 0.391 0.4083 1.33 0.692 2.56 0.00317 0.36 0.993 0.003065 1 0.496 2.03 PRS_PLINK_1.99526231496888e.06 755 Congenital anomalies of limbs Both 306 3285 15 congenital anomalies mediumspringgreen 3285, 306 825, 75 823, 78 817, 70 820, 83 0.0374 0.0599 0.532 0.2741 1.04 0.923 1.17 0.0485 0.167 0.772 0.1124 1.05 0.756 1.46 -0.0609 0.172 0.723 0.1407 0.941 0.672 1.32 0.109 0.166 0.51 0.2921 1.12 0.806 1.54 PRS_PLINK_1.99526231496888e.06 755.1 Congenital deformities of feet Both 153 1554 15 congenital anomalies mediumspringgreen 1554, 153 393, 35 385, 38 391, 38 385, 42 0.0738 0.0842 0.381 0.4194 1.08 0.913 1.27 0.111 0.241 0.645 0.1902 1.12 0.697 1.79 0.119 0.243 0.623 0.2052 1.13 0.7 1.81 0.212 0.236 0.371 0.4309 1.24 0.778 1.96 PRS_PLINK_1.99526231496888e.06 755.6 Other congenital anomalies of lower limb, including pelvic girdle Both 114 1299 15 congenital anomalies mediumspringgreen 1299, 114 326, 33 326, 30 324, 21 323, 30 -0.0994 0.103 0.333 0.478 0.905 0.74 1.11 -0.0826 0.259 0.75 0.1249 0.921 0.554 1.53 -0.438 0.282 0.121 0.9184 0.645 0.371 1.12 -0.107 0.261 0.682 0.1661 0.899 0.539 1.5 PRS_PLINK_1.99526231496888e.06 755.61 Congenital hip dysplasia and deformity Both 76 870 15 congenital anomalies mediumspringgreen 870, 76 220, 24 215, 20 217, 15 218, 17 -0.176 0.128 0.171 0.7662 0.839 0.652 1.08 -0.178 0.31 0.566 0.2471 0.837 0.456 1.54 -0.495 0.333 0.137 0.8621 0.61 0.318 1.17 -0.41 0.326 0.208 0.6815 0.663 0.35 1.26 PRS_PLINK_1.99526231496888e.06 756 Other congenital musculoskeletal anomalies Both 414 4400 15 congenital anomalies mediumspringgreen 4400, 414 1098, 105 1101, 108 1121, 101 1078, 100 -0.0287 0.0508 0.573 0.2422 0.972 0.88 1.07 0.00871 0.143 0.951 0.02162 1.01 0.762 1.34 -0.0451 0.145 0.756 0.1215 0.956 0.719 1.27 -0.0374 0.146 0.797 0.09836 0.963 0.724 1.28 PRS_PLINK_1.99526231496888e.06 756.3 Congenital anomalies of muscle, tendon, fascia, and connective tissue Both 60 635 15 congenital anomalies mediumspringgreen 635, 60 158, 15 159, 15 158, 16 159, 14 -0.0158 0.138 0.909 0.04157 0.984 0.752 1.29 -0.0437 0.371 0.906 0.04282 0.957 0.463 1.98 0.101 0.366 0.783 0.106 1.11 0.539 2.27 -0.157 0.381 0.681 0.167 0.855 0.405 1.81 PRS_PLINK_1.99526231496888e.06 756.5 Congenital osteodystrophies Both 297 3254 15 congenital anomalies mediumspringgreen 3254, 297 813, 70 816, 81 820, 74 804, 72 0.00681 0.0595 0.909 0.04148 1.01 0.896 1.13 0.127 0.169 0.452 0.3445 1.14 0.815 1.58 0.0624 0.173 0.718 0.144 1.06 0.759 1.49 0.0549 0.174 0.753 0.1232 1.06 0.751 1.49 PRS_PLINK_1.99526231496888e.06 758 Chromosomal anomalies and genetic disorders Both 88 1308 15 congenital anomalies mediumspringgreen 1308, 88 330, 19 325, 18 328, 24 325, 27 0.195 0.105 0.063 1.201 1.21 0.989 1.49 -0.0421 0.325 0.897 0.04729 0.959 0.507 1.81 0.224 0.307 0.466 0.3316 1.25 0.685 2.28 0.357 0.303 0.238 0.6238 1.43 0.79 2.59 PRS_PLINK_1.99526231496888e.06 758.1 Chromosomal anomalies Both 36 648 15 congenital anomalies mediumspringgreen 648, 36 162, 10 162, 8 163, 8 161, 10 0.102 0.159 0.521 0.2831 1.11 0.811 1.51 -0.192 0.452 0.67 0.1736 0.825 0.34 2 -0.25 0.452 0.58 0.2367 0.778 0.321 1.89 -0.0857 0.432 0.843 0.07426 0.918 0.393 2.14 PRS_PLINK_1.99526231496888e.06 759 Other and unspecified congenital anomalies Both 133 1586 15 congenital anomalies mediumspringgreen 1586, 133 401, 30 391, 37 395, 40 397, 26 -0.0345 0.0885 0.697 0.157 0.966 0.812 1.15 0.246 0.25 0.327 0.4861 1.28 0.783 2.09 0.323 0.248 0.193 0.7152 1.38 0.85 2.24 -0.134 0.271 0.621 0.2067 0.875 0.515 1.49 PRS_PLINK_1.99526231496888e.06 759.1 Anomalies of endocrine glands, congenital Both 64 704 15 congenital anomalies mediumspringgreen 704, 64 176, 12 176, 19 175, 20 176, 13 0.0224 0.122 0.855 0.06816 1.02 0.805 1.3 0.485 0.372 0.193 0.7151 1.62 0.783 3.37 0.617 0.373 0.0979 1.009 1.85 0.893 3.85 0.213 0.404 0.598 0.2233 1.24 0.561 2.73 PRS_PLINK_1.99526231496888e.06 760 Back pain Both 7241 82599 17 symptoms purple 82599, 7241 20650, 1770 20785, 1777 20739, 1857 20400, 1836 0.0267 0.0122 0.028 1.553 1.03 1 1.05 -0.00187 0.035 0.957 0.01892 0.998 0.932 1.07 0.0448 0.0346 0.196 0.708 1.05 0.977 1.12 0.0546 0.0348 0.116 0.9348 1.06 0.987 1.13 PRS_PLINK_1.99526231496888e.06 761 Cervicalgia Both 1226 13386 17 symptoms purple 13386, 1226 3344, 332 3356, 276 3339, 315 3342, 301 -0.0169 0.0302 0.575 0.2404 0.983 0.927 1.04 -0.184 0.0849 0.0307 1.513 0.832 0.705 0.983 -0.05 0.0823 0.543 0.2652 0.951 0.81 1.12 -0.092 0.0833 0.269 0.5699 0.912 0.775 1.07 PRS_PLINK_1.99526231496888e.06 764 Sciatica Both 1561 17542 17 symptoms purple 17542, 1561 4405, 389 4402, 354 4349, 407 4379, 411 0.0419 0.026 0.107 0.9718 1.04 0.991 1.1 -0.0923 0.0764 0.227 0.6444 0.912 0.785 1.06 0.0638 0.074 0.389 0.4102 1.07 0.922 1.23 0.0716 0.0739 0.333 0.4779 1.07 0.929 1.24 PRS_PLINK_1.99526231496888e.06 766 Neuralgia, neuritis, and radiculitis NOS Both 749 8615 17 symptoms purple 8615, 749 2158, 171 2179, 175 2122, 193 2154, 209 0.0758 0.0375 0.0436 1.361 1.08 1 1.16 0.0206 0.111 0.853 0.06909 1.02 0.821 1.27 0.14 0.109 0.198 0.7023 1.15 0.929 1.42 0.208 0.107 0.0524 1.281 1.23 0.998 1.52 PRS_PLINK_1.99526231496888e.06 770 Myalgia and myositis unspecified Both 414 4712 17 symptoms purple 4712, 414 1184, 84 1178, 90 1187, 130 1163, 109 0.12 0.0491 0.0145 1.839 1.13 1.02 1.24 0.0823 0.156 0.598 0.2236 1.09 0.8 1.47 0.436 0.145 0.0026 2.585 1.55 1.16 2.06 0.301 0.15 0.0452 1.345 1.35 1.01 1.81 PRS_PLINK_1.99526231496888e.06 771 Musculoskeletal symptoms referable to limbs Both 563 6326 17 symptoms purple 6326, 563 1578, 145 1580, 136 1592, 147 1571, 135 -0.0399 0.044 0.365 0.4376 0.961 0.881 1.05 -0.0616 0.124 0.619 0.208 0.94 0.737 1.2 0.0196 0.122 0.873 0.05922 1.02 0.803 1.3 -0.0546 0.124 0.661 0.1797 0.947 0.742 1.21 PRS_PLINK_1.99526231496888e.06 771.1 Swelling of limb Both 2688 33176 17 symptoms purple 33176, 2688 8292, 646 8289, 634 8390, 701 8198, 707 0.0383 0.0199 0.054 1.268 1.04 0.999 1.08 -0.0156 0.058 0.788 0.1037 0.985 0.879 1.1 0.0723 0.0567 0.202 0.6949 1.07 0.962 1.2 0.104 0.0567 0.0673 1.172 1.11 0.993 1.24 PRS_PLINK_1.99526231496888e.06 772 Symptoms of the muscles Both 423 4807 17 symptoms purple 4807, 423 1210, 112 1195, 98 1200, 88 1201, 125 0.0389 0.0498 0.435 0.3619 1.04 0.943 1.15 -0.121 0.143 0.398 0.3999 0.886 0.669 1.17 -0.218 0.147 0.138 0.8603 0.804 0.602 1.07 0.12 0.136 0.379 0.4219 1.13 0.864 1.47 PRS_PLINK_1.99526231496888e.06 773 Pain in limb Both 3953 45671 17 symptoms purple 45671, 3953 11455, 938 11379, 1000 11422, 1011 11400, 1002 0.0121 0.0166 0.468 0.33 1.01 0.98 1.05 0.0712 0.0473 0.133 0.8775 1.07 0.979 1.18 0.0802 0.0472 0.0893 1.049 1.08 0.988 1.19 0.0773 0.0474 0.103 0.9884 1.08 0.985 1.19 PRS_PLINK_1.99526231496888e.06 780 Hypothermia/Chills Both 97 1231 17 symptoms purple 1231, 97 312, 19 304, 27 307, 28 308, 23 -0.0109 0.104 0.917 0.0376 0.989 0.806 1.21 0.33 0.302 0.274 0.5627 1.39 0.77 2.51 0.422 0.301 0.161 0.7924 1.53 0.845 2.75 0.15 0.31 0.628 0.2022 1.16 0.633 2.14 PRS_PLINK_1.99526231496888e.06 781 Symptoms involving nervous and musculoskeletal systems Both 1200 13658 17 symptoms purple 13658, 1200 3422, 285 3434, 288 3401, 300 3397, 327 0.072 0.0298 0.0159 1.799 1.07 1.01 1.14 0.01 0.0868 0.908 0.04188 1.01 0.852 1.2 0.057 0.086 0.508 0.2941 1.06 0.894 1.25 0.153 0.0846 0.0707 1.151 1.17 0.987 1.38 PRS_PLINK_1.99526231496888e.06 782.3 Edema Both 745 11377 17 symptoms purple 11377, 745 2861, 169 2829, 185 2853, 205 2829, 186 0.0481 0.0371 0.195 0.7093 1.05 0.976 1.13 0.101 0.109 0.356 0.4489 1.11 0.893 1.37 0.201 0.107 0.0601 1.221 1.22 0.992 1.51 0.116 0.109 0.29 0.5375 1.12 0.906 1.39 PRS_PLINK_1.99526231496888e.06 782.6 Pallor and flushing Both 119 1247 17 symptoms purple 1247, 119 312, 31 312, 25 319, 32 304, 31 0.106 0.0933 0.257 0.5897 1.11 0.926 1.33 -0.25 0.275 0.364 0.439 0.779 0.454 1.34 -0.015 0.26 0.954 0.02044 0.985 0.592 1.64 0.0343 0.263 0.896 0.04766 1.03 0.619 1.73 PRS_PLINK_1.99526231496888e.06 783 Fever of unknown origin Both 2439 28217 17 symptoms purple 28217, 2439 7112, 591 7048, 600 7037, 606 7010, 641 0.0388 0.0209 0.0629 1.201 1.04 0.998 1.08 0.0249 0.0603 0.68 0.1675 1.03 0.911 1.15 0.039 0.0602 0.517 0.2866 1.04 0.924 1.17 0.0993 0.0595 0.0952 1.021 1.1 0.983 1.24 PRS_PLINK_1.99526231496888e.06 785 Abdominal pain Both 28423 225671 17 symptoms purple 225671, 28423 56602, 7011 56581, 7094 56996, 7318 55421, 6988 0.014 0.0063 0.0259 1.587 1.01 1 1.03 0.0131 0.0179 0.466 0.332 1.01 0.978 1.05 0.0404 0.0178 0.0231 1.636 1.04 1.01 1.08 0.0284 0.018 0.114 0.9417 1.03 0.993 1.07 PRS_PLINK_1.99526231496888e.06 788 Syncope and collapse Both 5658 63507 17 symptoms purple 63507, 5658 15911, 1476 15868, 1360 15831, 1437 15877, 1382 -0.00388 0.0138 0.779 0.1086 0.996 0.969 1.02 -0.0799 0.0392 0.0415 1.382 0.923 0.855 0.997 -0.0215 0.0387 0.579 0.2371 0.979 0.907 1.06 -0.0594 0.0391 0.129 0.8907 0.942 0.873 1.02 PRS_PLINK_1.99526231496888e.06 789 Nausea and vomiting Both 7405 85578 17 symptoms purple 85578, 7405 21384, 1852 21428, 1780 21627, 1928 21112, 1845 0.0181 0.0121 0.134 0.8735 1.02 0.994 1.04 -0.0412 0.0346 0.234 0.6317 0.96 0.897 1.03 0.0309 0.0339 0.362 0.441 1.03 0.965 1.1 0.0142 0.0343 0.679 0.1682 1.01 0.948 1.08 PRS_PLINK_1.99526231496888e.06 790 Nonspecific findings on examination of blood Both 87 1038 17 symptoms purple 1038, 87 259, 17 260, 26 258, 27 260, 17 0.0338 0.107 0.752 0.1235 1.03 0.838 1.28 0.446 0.316 0.158 0.8006 1.56 0.841 2.9 0.45 0.312 0.148 0.8284 1.57 0.852 2.89 0.0351 0.341 0.918 0.0372 1.04 0.531 2.02 PRS_PLINK_1.99526231496888e.06 790.1 Elevated sedimentation rate Both 38 573 17 symptoms purple 573, 38 147, 10 141, 10 143, 13 142, 5 -0.182 0.176 0.302 0.5205 0.834 0.59 1.18 0.0289 0.441 0.948 0.02332 1.03 0.434 2.44 0.219 0.421 0.604 0.2193 1.24 0.545 2.84 -0.741 0.516 0.151 0.8215 0.477 0.173 1.31 PRS_PLINK_1.99526231496888e.06 790.6 Other abnormal blood chemistry Both 3644 41750 17 symptoms purple 41750, 3644 10421, 860 10456, 924 10424, 940 10431, 919 0.0225 0.017 0.186 0.7308 1.02 0.989 1.06 0.0689 0.0493 0.163 0.7885 1.07 0.973 1.18 0.0877 0.0492 0.0745 1.128 1.09 0.991 1.2 0.062 0.0495 0.21 0.6777 1.06 0.966 1.17 PRS_PLINK_1.99526231496888e.06 791 Gangrene Both 244 3880 17 symptoms purple 3880, 244 975, 55 973, 55 964, 71 966, 63 0.0898 0.0633 0.156 0.8068 1.09 0.966 1.24 -0.0011 0.193 0.995 0.00198 0.999 0.684 1.46 0.273 0.183 0.135 0.8681 1.31 0.918 1.88 0.145 0.188 0.44 0.3569 1.16 0.8 1.67 PRS_PLINK_1.99526231496888e.06 792 Abnormal Papanicolaou smear of cervix and cervical HPV Female 76 727 17 symptoms purple 727, 76 186, 15 182, 26 177, 17 182, 18 0.0144 0.124 0.908 0.04209 1.01 0.796 1.29 0.637 0.341 0.0616 1.21 1.89 0.97 3.69 0.234 0.364 0.521 0.2835 1.26 0.619 2.58 0.218 0.354 0.538 0.2695 1.24 0.622 2.49 PRS_PLINK_1.99526231496888e.06 793 Nonspecific abnormal findings on radiological and other examination of musculoskeletal system Both 85 945 17 symptoms purple 945, 85 237, 21 236, 21 239, 26 233, 17 -0.0417 0.113 0.711 0.1479 0.959 0.769 1.2 0.0478 0.317 0.88 0.05552 1.05 0.564 1.95 0.212 0.302 0.482 0.3172 1.24 0.685 2.23 -0.17 0.328 0.605 0.2184 0.844 0.444 1.61 PRS_PLINK_1.99526231496888e.06 793.2 Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc) Both 349 3993 17 symptoms purple 3993, 349 999, 85 1003, 93 996, 91 995, 79 -0.0275 0.0562 0.624 0.2047 0.973 0.871 1.09 0.0923 0.156 0.553 0.2574 1.1 0.808 1.49 0.0678 0.156 0.664 0.1778 1.07 0.788 1.45 -0.057 0.162 0.725 0.1399 0.945 0.688 1.3 PRS_PLINK_1.99526231496888e.06 794 Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc) Both 96 1018 17 symptoms purple 1018, 96 255, 28 256, 24 252, 22 255, 22 -0.0804 0.11 0.464 0.3334 0.923 0.744 1.14 -0.14 0.285 0.623 0.2056 0.869 0.497 1.52 -0.215 0.295 0.466 0.332 0.806 0.453 1.44 -0.154 0.293 0.599 0.2225 0.857 0.482 1.52 PRS_PLINK_1.99526231496888e.06 797 Shock Both 77 1011 17 symptoms purple 1011, 77 253, 13 254, 21 251, 20 253, 23 0.12 0.109 0.274 0.5615 1.13 0.909 1.4 0.457 0.347 0.188 0.727 1.58 0.8 3.12 0.431 0.351 0.219 0.6601 1.54 0.774 3.06 0.539 0.344 0.118 0.9293 1.71 0.873 3.36 PRS_PLINK_1.99526231496888e.06 797.1 Cardiogenic shock Both 46 639 17 symptoms purple 639, 46 161, 9 159, 12 159, 14 160, 11 0.0365 0.143 0.799 0.09744 1.04 0.783 1.37 0.236 0.426 0.58 0.2368 1.27 0.55 2.92 0.49 0.423 0.246 0.6083 1.63 0.713 3.74 0.117 0.441 0.791 0.1021 1.12 0.474 2.67 PRS_PLINK_1.99526231496888e.06 798 Malaise and fatigue Both 2176 24992 17 symptoms purple 24992, 2176 6250, 539 6242, 567 6307, 524 6187, 544 0.0119 0.0224 0.596 0.2248 1.01 0.968 1.06 0.0514 0.0627 0.412 0.3851 1.05 0.931 1.19 -0.0319 0.0638 0.618 0.2093 0.969 0.855 1.1 0.025 0.0634 0.693 0.159 1.03 0.906 1.16 PRS_PLINK_1.99526231496888e.06 798.1 Chronic fatigue syndrome Both 447 4590 17 symptoms purple 4590, 447 1187, 113 1117, 111 1146, 117 1139, 106 0.0137 0.05 0.785 0.1052 1.01 0.919 1.12 0.0449 0.139 0.747 0.1268 1.05 0.796 1.37 0.0716 0.137 0.602 0.2202 1.07 0.821 1.41 -0.0205 0.141 0.884 0.05347 0.98 0.744 1.29 PRS_PLINK_1.99526231496888e.06 800 Fracture of lower limb Both 4863 50960 18 injuries & poisonings gray50 50960, 4863 12811, 1199 12673, 1146 12755, 1327 12701, 1187 0.0164 0.0149 0.271 0.5667 1.02 0.987 1.05 -0.0335 0.0431 0.438 0.3584 0.967 0.889 1.05 0.106 0.0417 0.0115 1.941 1.11 1.02 1.21 -0.000593 0.0428 0.989 0.004828 0.999 0.919 1.09 PRS_PLINK_1.99526231496888e.06 800.1 Fracture of neck of femur Both 1178 12464 18 injuries & poisonings gray50 12464, 1178 3124, 294 3117, 286 3105, 318 3114, 277 0.00262 0.0305 0.931 0.03085 1 0.945 1.06 -0.0241 0.0866 0.781 0.1072 0.976 0.824 1.16 0.0812 0.0847 0.338 0.4714 1.08 0.919 1.28 -0.0603 0.0874 0.49 0.31 0.941 0.793 1.12 PRS_PLINK_1.99526231496888e.06 800.2 Fracture of unspecified part of femur Both 105 1222 18 injuries & poisonings gray50 1222, 105 304, 21 306, 23 309, 31 301, 30 0.147 0.096 0.125 0.9022 1.16 0.96 1.4 0.0973 0.303 0.748 0.1262 1.1 0.609 1.99 0.322 0.288 0.263 0.5806 1.38 0.785 2.43 0.378 0.288 0.189 0.7243 1.46 0.83 2.57 PRS_PLINK_1.99526231496888e.06 800.3 Fracture of tibia and fibula Both 1569 16175 18 injuries & poisonings gray50 16175, 1569 4044, 353 4046, 389 4037, 416 4039, 411 0.0661 0.026 0.011 1.959 1.07 1.02 1.12 0.096 0.0767 0.21 0.6774 1.1 0.947 1.28 0.168 0.0756 0.0258 1.588 1.18 1.02 1.37 0.151 0.0758 0.0466 1.332 1.16 1 1.35 PRS_PLINK_1.99526231496888e.06 800.4 Fracture of patella Both 532 5519 18 injuries & poisonings gray50 5519, 532 1383, 120 1381, 114 1372, 164 1380, 133 0.065 0.0447 0.146 0.8356 1.07 0.978 1.16 -0.0524 0.135 0.699 0.1557 0.949 0.728 1.24 0.321 0.126 0.0105 1.978 1.38 1.08 1.76 0.106 0.131 0.417 0.3798 1.11 0.86 1.44 PRS_PLINK_1.99526231496888e.06 801 Fracture of ankle and foot Both 1561 16475 18 injuries & poisonings gray50 16475, 1561 4130, 388 4103, 385 4158, 382 4078, 405 0.0195 0.0263 0.458 0.3392 1.02 0.969 1.07 -0.00115 0.0751 0.988 0.005356 0.999 0.862 1.16 -0.0223 0.0752 0.767 0.1153 0.978 0.844 1.13 0.0603 0.0744 0.417 0.3796 1.06 0.918 1.23 PRS_PLINK_1.99526231496888e.06 801.1 Fracture of foot Both 1313 13664 18 injuries & poisonings gray50 13664, 1313 3428, 321 3406, 323 3435, 316 3390, 353 0.0393 0.0288 0.172 0.7634 1.04 0.983 1.1 0.00969 0.0823 0.906 0.04271 1.01 0.859 1.19 -0.0188 0.0827 0.82 0.08619 0.981 0.835 1.15 0.106 0.0808 0.188 0.7248 1.11 0.949 1.3 PRS_PLINK_1.99526231496888e.06 802 Fracture of pelvis Both 488 5176 18 injuries & poisonings gray50 5176, 488 1294, 120 1301, 118 1288, 125 1292, 124 0.0236 0.0469 0.614 0.212 1.02 0.934 1.12 -0.0213 0.135 0.875 0.05816 0.979 0.752 1.27 0.0558 0.133 0.675 0.1707 1.06 0.815 1.37 0.0377 0.133 0.777 0.1094 1.04 0.8 1.35 PRS_PLINK_1.99526231496888e.06 803 Fracture of upper limb Both 6088 61074 18 injuries & poisonings gray50 61074, 6088 15430, 1531 15246, 1469 15395, 1575 14985, 1512 0.0134 0.0134 0.315 0.5012 1.01 0.987 1.04 -0.0287 0.0383 0.454 0.3432 0.972 0.902 1.05 0.0298 0.0377 0.429 0.368 1.03 0.957 1.11 0.0175 0.0381 0.647 0.1893 1.02 0.944 1.1 PRS_PLINK_1.99526231496888e.06 803.1 Fracture of humerus Both 1139 12241 18 injuries & poisonings gray50 12241, 1139 3067, 279 3055, 272 3094, 306 3019, 282 0.0309 0.0306 0.312 0.5055 1.03 0.971 1.1 -0.0149 0.0888 0.867 0.06212 0.985 0.828 1.17 0.0861 0.0865 0.32 0.4952 1.09 0.92 1.29 0.0358 0.0883 0.685 0.1643 1.04 0.872 1.23 PRS_PLINK_1.99526231496888e.06 803.2 Fracture of radius and ulna Both 3930 38861 18 injuries & poisonings gray50 38861, 3930 9783, 982 9714, 954 9644, 999 9708, 994 0.0213 0.0167 0.202 0.6941 1.02 0.989 1.06 -0.0213 0.0476 0.654 0.1842 0.979 0.892 1.07 0.0315 0.0472 0.504 0.2973 1.03 0.941 1.13 0.0197 0.0473 0.677 0.1693 1.02 0.93 1.12 PRS_PLINK_1.99526231496888e.06 803.3 Fracture of clavicle or scapula Both 1111 10928 18 injuries & poisonings gray50 10928, 1111 2734, 288 2744, 256 2721, 288 2728, 279 -0.00154 0.0314 0.961 0.0174 0.998 0.939 1.06 -0.118 0.0898 0.188 0.7267 0.888 0.745 1.06 0.00245 0.0874 0.978 0.009801 1 0.845 1.19 -0.0282 0.0882 0.749 0.1256 0.972 0.818 1.16 PRS_PLINK_1.99526231496888e.06 804 Fracture of hand or wrist Both 2464 24889 18 injuries & poisonings gray50 24889, 2464 6230, 656 6254, 579 6256, 612 6147, 617 -0.00459 0.0211 0.828 0.08219 0.995 0.955 1.04 -0.129 0.0597 0.031 1.509 0.879 0.782 0.988 -0.0736 0.0589 0.212 0.6744 0.929 0.828 1.04 -0.0517 0.0589 0.38 0.4202 0.95 0.846 1.07 PRS_PLINK_1.99526231496888e.06 805 Fracture of vertebral column without mention of spinal cord injury Both 927 9901 18 injuries & poisonings gray50 9901, 927 2489, 214 2464, 238 2478, 235 2468, 239 0.00595 0.0343 0.862 0.06448 1.01 0.941 1.08 0.12 0.0981 0.222 0.6536 1.13 0.93 1.37 0.0951 0.0984 0.334 0.4762 1.1 0.907 1.33 0.117 0.0981 0.233 0.6323 1.12 0.927 1.36 PRS_PLINK_1.99526231496888e.06 807 Fracture of ribs Both 526 5437 18 injuries & poisonings gray50 5437, 526 1380, 143 1339, 129 1359, 129 1357, 125 -0.0404 0.0459 0.379 0.4214 0.96 0.878 1.05 -0.0689 0.127 0.587 0.2313 0.933 0.728 1.2 -0.0896 0.127 0.48 0.3192 0.914 0.713 1.17 -0.115 0.128 0.369 0.4324 0.891 0.694 1.15 PRS_PLINK_1.99526231496888e.06 809 Fracture of unspecified bones Both 887 9451 18 injuries & poisonings gray50 9451, 887 2392, 199 2340, 234 2368, 223 2349, 230 0.0224 0.0348 0.521 0.2833 1.02 0.955 1.09 0.192 0.1 0.0564 1.248 1.21 0.995 1.47 0.122 0.101 0.228 0.6426 1.13 0.926 1.38 0.159 0.101 0.115 0.9386 1.17 0.962 1.43 PRS_PLINK_1.99526231496888e.06 817 Concussion Both 180 1822 18 injuries & poisonings gray50 1822, 180 463, 48 448, 39 456, 36 455, 57 0.0511 0.0773 0.508 0.2939 1.05 0.905 1.22 -0.158 0.223 0.479 0.3198 0.854 0.551 1.32 -0.284 0.228 0.213 0.672 0.753 0.482 1.18 0.18 0.205 0.381 0.4191 1.2 0.801 1.79 PRS_PLINK_1.99526231496888e.06 818 Intracranial hemorrhage (injury) Both 333 3559 18 injuries & poisonings gray50 3559, 333 890, 81 893, 79 896, 73 880, 99 0.0776 0.0563 0.168 0.7741 1.08 0.968 1.21 -0.019 0.164 0.908 0.04205 0.981 0.712 1.35 -0.114 0.167 0.495 0.3057 0.892 0.643 1.24 0.199 0.156 0.202 0.6947 1.22 0.899 1.66 PRS_PLINK_1.99526231496888e.06 819 Skull and face fracture and other intercranial injury Both 2173 22133 18 injuries & poisonings gray50 22133, 2173 5538, 533 5534, 521 5557, 532 5496, 586 0.0295 0.0223 0.185 0.7329 1.03 0.986 1.08 -0.0214 0.0644 0.74 0.1308 0.979 0.863 1.11 -0.0065 0.0641 0.919 0.03655 0.994 0.876 1.13 0.0977 0.0628 0.12 0.9213 1.1 0.975 1.25 PRS_PLINK_1.99526231496888e.06 823 Torus fracture Both 1226 12588 18 injuries & poisonings gray50 12588, 1226 3143, 284 3152, 290 3168, 330 3121, 322 0.069 0.0293 0.0186 1.729 1.07 1.01 1.13 0.0194 0.087 0.824 0.08427 1.02 0.86 1.21 0.144 0.0846 0.0878 1.056 1.16 0.979 1.36 0.132 0.0851 0.12 0.9198 1.14 0.966 1.35 PRS_PLINK_1.99526231496888e.06 830 Dislocation Both 1519 15494 18 injuries & poisonings gray50 15494, 1519 3906, 426 3840, 363 3872, 353 3872, 377 -0.0281 0.0268 0.295 0.5298 0.972 0.923 1.02 -0.143 0.0749 0.0554 1.257 0.866 0.748 1 -0.179 0.0754 0.0173 1.763 0.836 0.721 0.969 -0.112 0.0742 0.131 0.8814 0.894 0.773 1.03 PRS_PLINK_1.99526231496888e.06 835 Internal derangement of knee Both 10995 112652 18 injuries & poisonings gray50 112652, 10995 28202, 2696 28099, 2741 28470, 2803 27846, 2750 0.0188 0.00994 0.0592 1.228 1.02 0.999 1.04 0.0205 0.0284 0.471 0.3267 1.02 0.965 1.08 0.0303 0.0283 0.283 0.5479 1.03 0.975 1.09 0.0336 0.0284 0.237 0.6257 1.03 0.978 1.09 PRS_PLINK_1.99526231496888e.06 836 Traumatic arthropathy Both 366 3840 18 injuries & poisonings gray50 3840, 366 980, 93 941, 93 974, 83 944, 97 0.0117 0.0551 0.831 0.08019 1.01 0.908 1.13 0.0401 0.153 0.793 0.1008 1.04 0.772 1.4 -0.111 0.157 0.477 0.321 0.895 0.658 1.22 0.0858 0.151 0.571 0.2436 1.09 0.81 1.47 PRS_PLINK_1.99526231496888e.06 840 Sprains and strains Both 358 3560 18 injuries & poisonings gray50 3560, 358 906, 89 883, 103 883, 67 887, 99 0.0164 0.054 0.762 0.1182 1.02 0.914 1.13 0.164 0.151 0.277 0.5573 1.18 0.876 1.59 -0.262 0.167 0.118 0.9292 0.77 0.554 1.07 0.113 0.153 0.459 0.3385 1.12 0.83 1.51 PRS_PLINK_1.99526231496888e.06 850 Hemorrhage or hematoma complicating a procedure Both 3428 38344 18 injuries & poisonings gray50 38344, 3428 9583, 860 9604, 815 9623, 876 9531, 876 0.0163 0.0178 0.358 0.4459 1.02 0.982 1.05 -0.0547 0.0509 0.283 0.5488 0.947 0.857 1.05 0.0173 0.0501 0.73 0.1367 1.02 0.922 1.12 0.0237 0.0502 0.637 0.1957 1.02 0.928 1.13 PRS_PLINK_1.99526231496888e.06 851 Complications of transplants and reattached limbs Both 94 1115 18 injuries & poisonings gray50 1115, 94 283, 25 277, 22 277, 28 277, 19 -0.0505 0.109 0.644 0.1908 0.951 0.767 1.18 -0.122 0.297 0.681 0.1669 0.885 0.495 1.58 0.138 0.283 0.626 0.2031 1.15 0.659 2 -0.242 0.307 0.43 0.3665 0.785 0.43 1.43 PRS_PLINK_1.99526231496888e.06 853 Complication of colostomy or enterostomy Both 276 3525 18 injuries & poisonings gray50 3525, 276 883, 72 887, 63 880, 73 875, 68 -0.0154 0.0629 0.807 0.09308 0.985 0.871 1.11 -0.129 0.177 0.466 0.3314 0.879 0.621 1.24 0.0163 0.172 0.924 0.03423 1.02 0.726 1.42 -0.0382 0.174 0.827 0.08275 0.962 0.684 1.35 PRS_PLINK_1.99526231496888e.06 854 Complications of cardiac/vascular device, implant, and graft Both 866 12213 18 injuries & poisonings gray50 12213, 866 3106, 225 3001, 204 3049, 223 3052, 214 0.00286 0.035 0.935 0.02927 1 0.936 1.07 -0.0653 0.0997 0.513 0.29 0.937 0.77 1.14 0.00841 0.0976 0.931 0.03089 1.01 0.833 1.22 -0.038 0.0987 0.701 0.1546 0.963 0.793 1.17 PRS_PLINK_1.99526231496888e.06 857 Mechanical complication of unspecified genitourinary device, implant, and graft Both 734 8833 18 injuries & poisonings gray50 8833, 734 2213, 177 2208, 198 2223, 204 2185, 155 -0.024 0.0389 0.537 0.2699 0.976 0.905 1.05 0.118 0.107 0.274 0.5626 1.12 0.911 1.39 0.138 0.107 0.196 0.7078 1.15 0.931 1.41 -0.109 0.114 0.338 0.4705 0.897 0.717 1.12 PRS_PLINK_1.99526231496888e.06 858 Complication of internal orthopedic device Both 1936 22544 18 injuries & poisonings gray50 22544, 1936 5651, 527 5637, 466 5612, 483 5636, 460 -0.036 0.0238 0.131 0.8839 0.965 0.921 1.01 -0.118 0.0663 0.0749 1.125 0.889 0.78 1.01 -0.0754 0.0657 0.251 0.5995 0.927 0.815 1.05 -0.126 0.0666 0.059 1.229 0.882 0.774 1 PRS_PLINK_1.99526231496888e.06 859 Complication due to other implant and internal device Both 2013 23394 18 injuries & poisonings gray50 23394, 2013 5860, 478 5839, 520 5919, 490 5772, 524 0.0237 0.0232 0.307 0.5124 1.02 0.978 1.07 0.0904 0.0659 0.17 0.7688 1.09 0.962 1.25 0.0171 0.0668 0.798 0.0982 1.02 0.892 1.16 0.111 0.0659 0.0931 1.031 1.12 0.982 1.27 PRS_PLINK_1.99526231496888e.06 860 Bone marrow or stem cell transplant Both 40 530 2 neoplasms darkcyan 530, 40 133, 8 133, 7 131, 8 133, 17 0.296 0.155 0.0557 1.254 1.34 0.993 1.82 -0.297 0.503 0.555 0.2553 0.743 0.277 1.99 -0.0556 0.48 0.908 0.04194 0.946 0.369 2.43 0.599 0.425 0.159 0.7992 1.82 0.791 4.19 PRS_PLINK_1.99526231496888e.06 870 Open wounds of head; neck; and trunk Both 2338 25149 18 injuries & poisonings gray50 25149, 2338 6288, 576 6293, 585 6295, 593 6265, 584 0.0149 0.0215 0.487 0.3125 1.02 0.973 1.06 0.0143 0.0613 0.815 0.08869 1.01 0.9 1.14 0.0334 0.0611 0.585 0.2327 1.03 0.917 1.17 0.0198 0.0614 0.747 0.1265 1.02 0.904 1.15 PRS_PLINK_1.99526231496888e.06 870.1 Open wound or laceration of eye or eyelid Both 183 1967 18 injuries & poisonings gray50 1967, 183 491, 50 494, 48 492, 37 489, 48 -0.0374 0.0776 0.63 0.2006 0.963 0.827 1.12 -0.0425 0.21 0.839 0.07609 0.958 0.636 1.45 -0.29 0.223 0.192 0.7171 0.748 0.484 1.16 -0.0351 0.21 0.867 0.06179 0.966 0.639 1.46 PRS_PLINK_1.99526231496888e.06 870.2 Open wound of ear Both 125 1439 18 injuries & poisonings gray50 1439, 125 360, 30 360, 31 362, 30 357, 34 0.0541 0.092 0.556 0.2546 1.06 0.881 1.26 0.0391 0.261 0.881 0.05515 1.04 0.624 1.73 0.00672 0.263 0.98 0.008941 1.01 0.601 1.69 0.176 0.258 0.495 0.3054 1.19 0.719 1.98 PRS_PLINK_1.99526231496888e.06 870.3 Other open wound of head and face Both 1943 20767 18 injuries & poisonings gray50 20767, 1943 5195, 461 5215, 493 5172, 497 5179, 492 0.031 0.0234 0.187 0.7293 1.03 0.985 1.08 0.0621 0.0676 0.358 0.4462 1.06 0.932 1.21 0.085 0.0675 0.208 0.6817 1.09 0.954 1.24 0.0679 0.0678 0.316 0.4999 1.07 0.937 1.22 PRS_PLINK_1.99526231496888e.06 870.4 Open wound of nose and sinus Both 148 1535 18 injuries & poisonings gray50 1535, 148 385, 42 382, 31 385, 34 382, 41 -0.0011 0.0844 0.99 0.004526 0.999 0.847 1.18 -0.311 0.244 0.202 0.6942 0.732 0.454 1.18 -0.186 0.238 0.434 0.3622 0.83 0.521 1.32 -0.0496 0.23 0.829 0.0814 0.952 0.607 1.49 PRS_PLINK_1.99526231496888e.06 870.6 Open wound of neck Both 48 511 18 injuries & poisonings gray50 511, 48 129, 16 127, 14 127, 9 128, 9 -0.273 0.155 0.0774 1.111 0.761 0.562 1.03 -0.115 0.374 0.759 0.1196 0.892 0.428 1.86 -0.503 0.417 0.228 0.6418 0.605 0.267 1.37 -0.543 0.417 0.193 0.715 0.581 0.257 1.32 PRS_PLINK_1.99526231496888e.06 871 Open wounds of extremities Both 2888 29962 18 injuries & poisonings gray50 29962, 2888 7569, 712 7432, 682 7529, 762 7423, 730 0.0159 0.0194 0.411 0.386 1.02 0.978 1.06 -0.0252 0.056 0.652 0.1856 0.975 0.874 1.09 0.0762 0.0546 0.163 0.7884 1.08 0.97 1.2 0.0487 0.0552 0.378 0.423 1.05 0.942 1.17 PRS_PLINK_1.99526231496888e.06 871.1 Open wound of hand except finger(s) Both 41 369 18 injuries & poisonings gray50 369, 41 93, 6 93, 11 91, 15 92, 9 0.157 0.155 0.311 0.5072 1.17 0.864 1.58 0.768 0.508 0.13 0.8853 2.16 0.797 5.83 0.95 0.476 0.0459 1.338 2.59 1.02 6.58 0.264 0.507 0.602 0.2201 1.3 0.482 3.51 PRS_PLINK_1.99526231496888e.06 871.2 Open wound of finger(s) Both 62 656 18 injuries & poisonings gray50 656, 62 165, 17 164, 11 164, 15 163, 19 0.099 0.135 0.462 0.3352 1.1 0.848 1.44 -0.439 0.392 0.263 0.5801 0.645 0.299 1.39 -0.197 0.362 0.586 0.2318 0.821 0.403 1.67 0.0457 0.347 0.895 0.04814 1.05 0.531 2.06 PRS_PLINK_1.99526231496888e.06 871.3 Open wound of foot except toe(s) alone Both 118 1315 18 injuries & poisonings gray50 1315, 118 331, 31 327, 18 328, 31 329, 38 0.083 0.0928 0.371 0.4306 1.09 0.906 1.3 -0.476 0.298 0.11 0.9588 0.621 0.346 1.11 0.0527 0.261 0.84 0.07559 1.05 0.632 1.76 0.218 0.251 0.384 0.4155 1.24 0.761 2.03 PRS_PLINK_1.99526231496888e.06 872 Traumatic amputation Both 349 3368 18 injuries & poisonings gray50 3368, 349 847, 81 837, 98 841, 76 842, 94 0.0134 0.0556 0.81 0.09134 1.01 0.909 1.13 0.186 0.157 0.236 0.6278 1.2 0.886 1.64 -0.0624 0.166 0.706 0.1511 0.939 0.679 1.3 0.158 0.159 0.32 0.4949 1.17 0.858 1.6 PRS_PLINK_1.99526231496888e.06 873 Broken tooth Both 158 1673 18 injuries & poisonings gray50 1673, 158 420, 30 417, 40 419, 50 417, 38 0.108 0.0816 0.186 0.7312 1.11 0.949 1.31 0.304 0.247 0.217 0.663 1.36 0.836 2.2 0.496 0.237 0.0365 1.438 1.64 1.03 2.62 0.264 0.251 0.293 0.5338 1.3 0.796 2.13 PRS_PLINK_1.99526231496888e.06 874 Complication of amputation stump Both 87 1237 18 injuries & poisonings gray50 1237, 87 319, 21 300, 18 309, 22 309, 26 0.116 0.103 0.262 0.5823 1.12 0.917 1.38 -0.0922 0.322 0.774 0.111 0.912 0.485 1.71 0.15 0.308 0.627 0.2025 1.16 0.635 2.12 0.239 0.296 0.42 0.377 1.27 0.711 2.27 PRS_PLINK_1.99526231496888e.06 905 Late effects of musculoskeletal and connective tissue injuries Both 113 1185 18 injuries & poisonings gray50 1185, 113 305, 27 288, 22 301, 34 291, 30 0.0704 0.0973 0.47 0.3282 1.07 0.887 1.3 -0.18 0.292 0.538 0.2696 0.836 0.472 1.48 0.242 0.266 0.364 0.4395 1.27 0.756 2.15 0.157 0.273 0.564 0.2485 1.17 0.686 2 PRS_PLINK_1.99526231496888e.06 907 Injuries to the nervous system Both 910 9756 18 injuries & poisonings gray50 9756, 910 2464, 215 2434, 221 2457, 239 2397, 233 0.0293 0.0343 0.393 0.4056 1.03 0.963 1.1 0.0386 0.0997 0.699 0.1555 1.04 0.855 1.26 0.104 0.0981 0.289 0.5394 1.11 0.916 1.34 0.108 0.0988 0.274 0.5622 1.11 0.918 1.35 PRS_PLINK_1.99526231496888e.06 915 Superficial injury without mention of infection Both 2732 30875 18 injuries & poisonings gray50 30875, 2732 7724, 657 7725, 675 7707, 715 7711, 685 0.0247 0.0197 0.211 0.675 1.02 0.986 1.07 0.0271 0.0571 0.634 0.1976 1.03 0.919 1.15 0.0911 0.0564 0.106 0.9746 1.1 0.981 1.22 0.0453 0.057 0.426 0.3702 1.05 0.936 1.17 PRS_PLINK_1.99526231496888e.06 916 Contusion Both 958 10427 18 injuries & poisonings gray50 10427, 958 2621, 232 2591, 240 2618, 233 2594, 252 0.0401 0.0331 0.226 0.6456 1.04 0.975 1.11 0.0403 0.0959 0.674 0.1713 1.04 0.863 1.26 0.00717 0.0965 0.941 0.02653 1.01 0.834 1.22 0.0923 0.095 0.331 0.4796 1.1 0.91 1.32 PRS_PLINK_1.99526231496888e.06 930 Allergic reaction to food Both 134 1399 18 injuries & poisonings gray50 1399, 134 352, 32 348, 45 351, 29 348, 28 -0.0876 0.0927 0.345 0.4628 0.916 0.764 1.1 0.333 0.24 0.165 0.7835 1.4 0.872 2.23 -0.102 0.261 0.698 0.1564 0.903 0.541 1.51 -0.118 0.264 0.654 0.1843 0.889 0.53 1.49 PRS_PLINK_1.99526231496888e.06 938 Dermatitis due to solar radiation Both 250 2641 18 injuries & poisonings gray50 2641, 250 667, 46 655, 80 663, 64 656, 60 0.0374 0.0637 0.557 0.2539 1.04 0.916 1.18 0.555 0.192 0.00381 2.419 1.74 1.2 2.54 0.325 0.199 0.102 0.9909 1.38 0.937 2.04 0.282 0.201 0.16 0.7951 1.33 0.894 1.96 PRS_PLINK_1.99526231496888e.06 938.2 Chronic dermatitis due to solar radiation Both 168 1712 18 injuries & poisonings gray50 1712, 168 429, 32 433, 62 427, 40 423, 34 -0.0583 0.0799 0.466 0.3319 0.943 0.807 1.1 0.643 0.226 0.00448 2.349 1.9 1.22 2.96 0.226 0.243 0.351 0.4542 1.25 0.779 2.02 0.0689 0.25 0.783 0.1062 1.07 0.656 1.75 PRS_PLINK_1.99526231496888e.06 939 Atopic/contact dermatitis due to other or unspecified Both 1350 15276 13 dermatologic firebrick 15276, 1350 3835, 325 3806, 314 3833, 359 3797, 352 0.0478 0.0279 0.0861 1.065 1.05 0.993 1.11 -0.0283 0.0822 0.731 0.1363 0.972 0.827 1.14 0.101 0.0798 0.206 0.6871 1.11 0.946 1.29 0.0942 0.0802 0.24 0.6198 1.1 0.939 1.29 PRS_PLINK_1.99526231496888e.06 941 Adverse reaction to serum or vaccine Both 152 1568 18 injuries & poisonings gray50 1568, 152 394, 38 393, 32 389, 38 392, 44 0.107 0.0823 0.194 0.7128 1.11 0.947 1.31 -0.196 0.247 0.428 0.3683 0.822 0.507 1.33 0.0239 0.237 0.92 0.03633 1.02 0.643 1.63 0.139 0.231 0.549 0.2604 1.15 0.73 1.81 PRS_PLINK_1.99526231496888e.06 942 Infusion and transfusion reaction Both 62 732 18 injuries & poisonings gray50 732, 62 182, 14 183, 16 183, 12 183, 20 0.113 0.124 0.362 0.4419 1.12 0.878 1.43 0.0853 0.365 0.815 0.08885 1.09 0.533 2.22 -0.19 0.387 0.624 0.2049 0.827 0.387 1.77 0.302 0.353 0.392 0.4069 1.35 0.677 2.7 PRS_PLINK_1.99526231496888e.06 946 Anaphylactic shock NOS Both 333 4070 18 injuries & poisonings gray50 4070, 333 1018, 93 1024, 72 1012, 80 1015, 88 -0.00243 0.057 0.966 0.01503 0.998 0.892 1.12 -0.266 0.162 0.0997 1.001 0.766 0.558 1.05 -0.139 0.158 0.38 0.4208 0.871 0.639 1.19 -0.0442 0.155 0.775 0.1108 0.957 0.707 1.3 PRS_PLINK_1.99526231496888e.06 947 Urticaria Both 249 2770 18 injuries & poisonings gray50 2770, 249 693, 70 691, 44 693, 74 692, 61 0.0324 0.0657 0.622 0.2061 1.03 0.908 1.17 -0.457 0.197 0.0208 1.683 0.633 0.43 0.933 0.0638 0.174 0.714 0.1465 1.07 0.758 1.5 -0.124 0.182 0.495 0.3051 0.883 0.618 1.26 PRS_PLINK_1.99526231496888e.06 949 Allergies, other Both 280 3065 18 injuries & poisonings gray50 3065, 280 767, 85 766, 58 764, 68 766, 69 -0.0239 0.0633 0.705 0.1516 0.976 0.863 1.11 -0.379 0.176 0.0315 1.502 0.684 0.484 0.967 -0.22 0.17 0.194 0.7131 0.802 0.575 1.12 -0.195 0.169 0.25 0.6021 0.823 0.59 1.15 PRS_PLINK_1.99526231496888e.06 952 Spinal cord injury without evidence of spinal bone injury Both 296 3088 18 injuries & poisonings gray50 3088, 296 789, 71 761, 80 781, 84 756, 61 -0.0464 0.0611 0.448 0.3489 0.955 0.847 1.08 0.148 0.169 0.383 0.4168 1.16 0.832 1.62 0.174 0.167 0.3 0.5234 1.19 0.857 1.65 -0.108 0.181 0.55 0.2599 0.898 0.63 1.28 PRS_PLINK_1.99526231496888e.06 957 Injury to other and unspecified nerves Both 158 1935 18 injuries & poisonings gray50 1935, 158 492, 39 479, 43 480, 41 484, 35 0.00717 0.0825 0.931 0.03118 1.01 0.857 1.18 0.117 0.227 0.608 0.216 1.12 0.72 1.75 0.0791 0.229 0.73 0.1369 1.08 0.691 1.7 -0.0827 0.238 0.728 0.1378 0.921 0.578 1.47 PRS_PLINK_1.99526231496888e.06 958 Certain early complications of trauma or procedure Both 310 3587 18 injuries & poisonings gray50 3587, 310 902, 94 895, 61 893, 78 896, 77 -0.0282 0.0594 0.635 0.197 0.972 0.865 1.09 -0.426 0.17 0.0121 1.918 0.653 0.468 0.911 -0.156 0.159 0.327 0.4857 0.855 0.626 1.17 -0.186 0.16 0.244 0.6131 0.83 0.607 1.14 PRS_PLINK_1.99526231496888e.06 958.1 Postoperative shock Both 30 385 18 injuries & poisonings gray50 385, 30 98, 7 95, 6 97, 10 95, 7 0.0525 0.175 0.763 0.1173 1.05 0.749 1.48 -0.0836 0.531 0.875 0.05797 0.92 0.325 2.61 0.401 0.49 0.413 0.384 1.49 0.571 3.91 0.0231 0.521 0.965 0.01566 1.02 0.368 2.84 PRS_PLINK_1.99526231496888e.06 958.2 Traumatic and surgical subcutaneous emphysema Both 51 506 18 injuries & poisonings gray50 506, 51 129, 21 124, 10 126, 10 127, 10 -0.372 0.161 0.0214 1.67 0.69 0.503 0.946 -0.65 0.389 0.0951 1.022 0.522 0.243 1.12 -0.646 0.391 0.0981 1.008 0.524 0.244 1.13 -0.756 0.392 0.054 1.268 0.47 0.218 1.01 PRS_PLINK_1.99526231496888e.06 960 Poisoning by antibiotics Both 12268 135935 18 injuries & poisonings gray50 135935, 12268 33964, 2993 34353, 3031 33601, 3118 33978, 3124 0.0246 0.00939 0.00865 2.063 1.02 1.01 1.04 0.00167 0.0269 0.95 0.0221 1 0.95 1.06 0.0532 0.0267 0.0465 1.332 1.05 1 1.11 0.0452 0.0267 0.0906 1.043 1.05 0.993 1.1 PRS_PLINK_1.99526231496888e.06 960.2 Allergy/adverse effect of penicillin Both 10735 118729 18 injuries & poisonings gray50 118729, 10735 29735, 2605 29854, 2649 29437, 2741 29668, 2739 0.0284 0.01 0.00469 2.329 1.03 1.01 1.05 0.0132 0.0288 0.645 0.1902 1.01 0.958 1.07 0.0633 0.0286 0.0268 1.571 1.07 1.01 1.13 0.0556 0.0286 0.0521 1.283 1.06 1 1.12 PRS_PLINK_1.99526231496888e.06 961 Poisoning by other anti-infectives Both 253 3125 18 injuries & poisonings gray50 3125, 253 781, 66 784, 61 780, 57 779, 69 0.0215 0.0658 0.744 0.1283 1.02 0.898 1.16 -0.0778 0.183 0.671 0.1732 0.925 0.646 1.32 -0.145 0.186 0.436 0.3605 0.865 0.601 1.25 0.0682 0.178 0.702 0.1538 1.07 0.755 1.52 PRS_PLINK_1.99526231496888e.06 961.1 Poisoning/allergy of sulfonamides Both 575 6701 18 injuries & poisonings gray50 6701, 575 1688, 171 1661, 125 1676, 161 1674, 118 -0.065 0.0444 0.143 0.8439 0.937 0.859 1.02 -0.296 0.122 0.0152 1.818 0.743 0.585 0.945 -0.0515 0.115 0.654 0.1847 0.95 0.758 1.19 -0.356 0.124 0.00409 2.388 0.7 0.549 0.893 PRS_PLINK_1.99526231496888e.06 962 Poisoning by hormones and synthetic substitutes Both 192 2752 18 injuries & poisonings gray50 2752, 192 701, 50 680, 37 685, 49 685, 56 0.0974 0.0719 0.176 0.755 1.1 0.957 1.27 -0.258 0.219 0.239 0.6214 0.772 0.502 1.19 0.00362 0.205 0.986 0.006143 1 0.671 1.5 0.13 0.199 0.516 0.2877 1.14 0.77 1.68 PRS_PLINK_1.99526231496888e.06 962.3 Hormones and synthetic substitutes causing adverse effects in therapeutic use Both 188 2693 18 injuries & poisonings gray50 2693, 188 686, 46 663, 39 672, 47 672, 56 0.122 0.0726 0.0928 1.033 1.13 0.98 1.3 -0.116 0.22 0.597 0.2239 0.89 0.578 1.37 0.0302 0.211 0.886 0.0524 1.03 0.681 1.56 0.209 0.203 0.303 0.5184 1.23 0.828 1.84 PRS_PLINK_1.99526231496888e.06 963 Poisoning by primarily systemic agents Both 148 1787 18 injuries & poisonings gray50 1787, 148 446, 42 450, 34 444, 34 446, 38 -0.0407 0.0863 0.637 0.1958 0.96 0.811 1.14 -0.213 0.236 0.368 0.4342 0.808 0.508 1.28 -0.198 0.236 0.402 0.3955 0.82 0.516 1.3 -0.0733 0.231 0.751 0.1242 0.929 0.591 1.46 PRS_PLINK_1.99526231496888e.06 964 Poisoning by agents primarily affecting blood constituents Both 121 1978 18 injuries & poisonings gray50 1978, 121 501, 24 492, 33 490, 28 495, 36 0.152 0.0872 0.0811 1.091 1.16 0.981 1.38 0.343 0.271 0.205 0.689 1.41 0.829 2.4 0.189 0.278 0.496 0.3049 1.21 0.701 2.08 0.431 0.267 0.106 0.9747 1.54 0.912 2.6 PRS_PLINK_1.99526231496888e.06 964.1 Anticoagulants causing adverse effects Both 116 1929 18 injuries & poisonings gray50 1929, 116 483, 20 482, 33 482, 27 482, 36 0.198 0.0891 0.0265 1.577 1.22 1.02 1.45 0.503 0.284 0.0768 1.115 1.65 0.947 2.88 0.284 0.292 0.331 0.4796 1.33 0.749 2.35 0.603 0.281 0.0319 1.497 1.83 1.05 3.17 PRS_PLINK_1.99526231496888e.06 965 Poisoning by analgesics, antipyretics, and antirheumatics Both 3968 45867 18 injuries & poisonings gray50 45867, 3968 11458, 1015 11560, 981 11372, 1001 11467, 971 -0.00216 0.0165 0.896 0.04756 0.998 0.966 1.03 -0.0404 0.0467 0.386 0.413 0.96 0.876 1.05 -0.00484 0.0465 0.917 0.03759 0.995 0.909 1.09 -0.0377 0.0468 0.42 0.3763 0.963 0.879 1.06 PRS_PLINK_1.99526231496888e.06 965.1 Opiates and related narcotics causing adverse effects in therapeutic use Both 758 8661 18 injuries & poisonings gray50 8661, 758 2171, 192 2183, 172 2168, 190 2136, 204 0.0305 0.038 0.421 0.3753 1.03 0.957 1.11 -0.116 0.109 0.287 0.5425 0.891 0.719 1.1 -0.012 0.106 0.91 0.04103 0.988 0.802 1.22 0.0778 0.105 0.458 0.3391 1.08 0.88 1.33 PRS_PLINK_1.99526231496888e.06 965.2 Antirheumatics causing adverse effects in therapeutic use Both 334 3867 18 injuries & poisonings gray50 3867, 334 968, 73 969, 73 966, 91 964, 97 0.102 0.0561 0.068 1.168 1.11 0.992 1.24 -0.0109 0.17 0.949 0.02278 0.989 0.709 1.38 0.217 0.162 0.182 0.7396 1.24 0.903 1.71 0.293 0.16 0.067 1.174 1.34 0.98 1.84 PRS_PLINK_1.99526231496888e.06 965.3 Salicylates causing adverse effects in therapeutic use Both 253 2948 18 injuries & poisonings gray50 2948, 253 737, 67 741, 66 734, 66 735, 54 -0.0912 0.0671 0.174 0.7598 0.913 0.8 1.04 -0.0253 0.18 0.888 0.0515 0.975 0.685 1.39 0.00811 0.18 0.964 0.0159 1.01 0.708 1.43 -0.183 0.188 0.332 0.4784 0.833 0.576 1.21 PRS_PLINK_1.99526231496888e.06 966 Poisoning by anticonvulsants and anti-Parkinsonism drugs Both 347 4037 18 injuries & poisonings gray50 4037, 347 1015, 88 1019, 90 994, 74 1009, 95 0.0574 0.0555 0.301 0.522 1.06 0.95 1.18 0.0149 0.155 0.924 0.03449 1.01 0.749 1.38 -0.156 0.163 0.337 0.4721 0.855 0.621 1.18 0.0932 0.154 0.544 0.2646 1.1 0.812 1.48 PRS_PLINK_1.99526231496888e.06 967 Adverse effects of sedatives or other central nervous system depressants and anesthetics Both 404 4411 18 injuries & poisonings gray50 4411, 404 1101, 93 1113, 95 1093, 108 1102, 108 0.0719 0.0522 0.169 0.7733 1.07 0.97 1.19 0.00895 0.151 0.953 0.02101 1.01 0.75 1.36 0.171 0.147 0.245 0.6116 1.19 0.889 1.58 0.152 0.147 0.301 0.5217 1.16 0.873 1.55 PRS_PLINK_1.99526231496888e.06 969 Poisoning by psychotropic agents Both 1325 15609 18 injuries & poisonings gray50 15609, 1325 3907, 345 3905, 315 3910, 313 3879, 352 0.0232 0.0287 0.42 0.377 1.02 0.967 1.08 -0.0954 0.081 0.239 0.6211 0.909 0.776 1.07 -0.0974 0.0811 0.23 0.6379 0.907 0.774 1.06 0.0337 0.079 0.67 0.1742 1.03 0.886 1.21 PRS_PLINK_1.99526231496888e.06 971 Poisoning by drugs primarily affecting the autonomic nervous system Both 121 1510 18 injuries & poisonings gray50 1510, 121 379, 29 378, 30 375, 36 378, 26 -0.0666 0.0978 0.496 0.3048 0.936 0.772 1.13 0.0172 0.266 0.949 0.02296 1.02 0.604 1.71 0.229 0.256 0.371 0.4307 1.26 0.761 2.08 -0.124 0.274 0.65 0.1871 0.883 0.516 1.51 PRS_PLINK_1.99526231496888e.06 972 Poisoning by agents primarily affecting the cardiovascular system Both 157 2049 18 injuries & poisonings gray50 2049, 157 532, 39 493, 33 516, 41 508, 43 0.048 0.0816 0.556 0.255 1.05 0.894 1.23 -0.124 0.241 0.606 0.2174 0.883 0.551 1.42 0.0861 0.228 0.706 0.1512 1.09 0.697 1.71 0.187 0.227 0.41 0.3873 1.21 0.772 1.88 PRS_PLINK_1.99526231496888e.06 972.6 Antihypertensive agents causing adverse effects Both 51 670 18 injuries & poisonings gray50 670, 51 173, 12 163, 14 167, 12 167, 13 0.0575 0.142 0.686 0.164 1.06 0.802 1.4 0.121 0.393 0.757 0.1207 1.13 0.523 2.44 0.0715 0.406 0.86 0.06541 1.07 0.485 2.38 0.165 0.402 0.681 0.1671 1.18 0.537 2.59 PRS_PLINK_1.99526231496888e.06 973 Poisoning by agents primarily affecting the gastrointestinal system Both 66 835 18 injuries & poisonings gray50 835, 66 209, 12 209, 13 208, 17 209, 24 0.324 0.118 0.00605 2.219 1.38 1.1 1.74 -0.0148 0.393 0.97 0.01323 0.985 0.456 2.13 0.491 0.382 0.198 0.7027 1.63 0.773 3.46 0.635 0.354 0.0729 1.137 1.89 0.943 3.78 PRS_PLINK_1.99526231496888e.06 974 Poisoning by water, mineral, and uric acid metabolism drugs Both 35 711 18 injuries & poisonings gray50 711, 35 183, 11 173, 4 182, 6 173, 14 0.159 0.159 0.317 0.4984 1.17 0.858 1.6 -0.925 0.539 0.0859 1.066 0.397 0.138 1.14 -0.504 0.49 0.304 0.5172 0.604 0.231 1.58 0.349 0.409 0.394 0.4043 1.42 0.635 3.16 PRS_PLINK_1.99526231496888e.06 975 Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system Both 41 509 18 injuries & poisonings gray50 509, 41 128, 10 127, 14 128, 10 126, 7 -0.199 0.166 0.233 0.6327 0.82 0.592 1.14 0.269 0.417 0.52 0.2844 1.31 0.577 2.96 0.0274 0.446 0.951 0.02185 1.03 0.429 2.46 -0.328 0.488 0.501 0.3 0.72 0.277 1.87 PRS_PLINK_1.99526231496888e.06 976 Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs Both 39 449 18 injuries & poisonings gray50 449, 39 115, 11 111, 9 111, 9 112, 10 0.018 0.171 0.916 0.03789 1.02 0.728 1.42 -0.16 0.441 0.717 0.1446 0.852 0.359 2.02 0.0559 0.461 0.903 0.04412 1.06 0.428 2.61 -0.0243 0.447 0.957 0.01928 0.976 0.407 2.34 PRS_PLINK_1.99526231496888e.06 977 Personal history of allergy to medicinal agents Both 143 1740 18 injuries & poisonings gray50 1740, 143 438, 31 434, 37 437, 44 430, 31 -0.0216 0.0879 0.806 0.09347 0.979 0.824 1.16 0.22 0.249 0.376 0.4245 1.25 0.765 2.03 0.373 0.24 0.121 0.9167 1.45 0.906 2.32 0.0467 0.259 0.857 0.06716 1.05 0.631 1.74 PRS_PLINK_1.99526231496888e.06 979 Adverse drug events and drug allergies Both 458 5403 18 injuries & poisonings gray50 5403, 458 1363, 109 1341, 112 1349, 124 1350, 113 0.00314 0.049 0.949 0.0228 1 0.911 1.1 0.0465 0.139 0.739 0.1316 1.05 0.797 1.38 0.141 0.136 0.299 0.5247 1.15 0.882 1.5 0.0544 0.139 0.695 0.1577 1.06 0.804 1.39 PRS_PLINK_1.99526231496888e.06 981 Toxic effect of (non-ethyl) alcohol and petroleum and other solvents Both 136 1611 18 injuries & poisonings gray50 1611, 136 402, 35 403, 30 402, 40 403, 31 -0.0527 0.09 0.558 0.2532 0.949 0.795 1.13 -0.164 0.256 0.521 0.2832 0.849 0.514 1.4 0.126 0.239 0.597 0.2239 1.13 0.711 1.81 -0.121 0.253 0.632 0.1996 0.886 0.54 1.45 PRS_PLINK_1.99526231496888e.06 986 Toxic effect of carbon monoxide Both 45 460 18 injuries & poisonings gray50 460, 45 115, 9 115, 13 115, 12 115, 11 0.057 0.151 0.706 0.1513 1.06 0.788 1.42 0.288 0.448 0.52 0.2838 1.33 0.554 3.21 0.34 0.441 0.441 0.3555 1.4 0.592 3.33 0.324 0.458 0.479 0.32 1.38 0.564 3.39 PRS_PLINK_1.99526231496888e.06 987 Toxic effect of other gases, fumes, or vapors Both 61 764 18 injuries & poisonings gray50 764, 61 191, 15 191, 14 192, 14 190, 18 0.0721 0.129 0.577 0.2389 1.07 0.834 1.38 -0.136 0.376 0.718 0.144 0.873 0.418 1.82 -0.0623 0.369 0.866 0.06263 0.94 0.456 1.94 0.0894 0.355 0.801 0.09618 1.09 0.545 2.19 PRS_PLINK_1.99526231496888e.06 988 Toxic effect of noxious substances eaten as food Both 86 877 18 injuries & poisonings gray50 877, 86 226, 20 213, 29 219, 19 219, 18 -0.114 0.117 0.33 0.4816 0.892 0.71 1.12 0.384 0.3 0.201 0.6966 1.47 0.815 2.64 -0.0371 0.323 0.909 0.04164 0.964 0.512 1.81 -0.058 0.331 0.861 0.06514 0.944 0.494 1.8 PRS_PLINK_1.99526231496888e.06 989 Toxic effect of other substances, chiefly nonmedicinal as to source Both 53 617 18 injuries & poisonings gray50 617, 53 157, 10 153, 17 155, 11 152, 15 -0.0552 0.142 0.697 0.1569 0.946 0.717 1.25 0.54 0.399 0.176 0.7554 1.72 0.785 3.75 0.0797 0.425 0.851 0.06999 1.08 0.471 2.49 0.364 0.403 0.367 0.4353 1.44 0.653 3.17 PRS_PLINK_1.99526231496888e.06 990 Effects radiation NOS Both 2013 21824 18 injuries & poisonings gray50 21824, 2013 5480, 498 5436, 495 5461, 524 5437, 495 0.00176 0.0233 0.94 0.02706 1 0.957 1.05 0.00239 0.0662 0.971 0.0127 1 0.88 1.14 0.0575 0.0654 0.379 0.4208 1.06 0.932 1.2 0.00166 0.0663 0.98 0.008756 1 0.88 1.14 PRS_PLINK_1.99526231496888e.06 994 Sepsis and SIRS Both 1560 21063 18 injuries & poisonings gray50 21063, 1560 5272, 384 5278, 385 5255, 379 5249, 412 0.0275 0.0259 0.288 0.5401 1.03 0.977 1.08 0.00463 0.0746 0.951 0.02202 1 0.868 1.16 -0.0063 0.0749 0.933 0.03014 0.994 0.858 1.15 0.0779 0.0735 0.29 0.5381 1.08 0.936 1.25 PRS_PLINK_1.99526231496888e.06 994.2 Sepsis Both 1560 21063 18 injuries & poisonings gray50 21063, 1560 5272, 384 5278, 385 5255, 379 5249, 412 0.0275 0.0259 0.288 0.5401 1.03 0.977 1.08 0.00463 0.0746 0.951 0.02202 1 0.868 1.16 -0.0063 0.0749 0.933 0.03014 0.994 0.858 1.15 0.0779 0.0735 0.29 0.5381 1.08 0.936 1.25 PRS_PLINK_1.99526231496888e.06 1000 Burns Both 381 4263 18 injuries & poisonings gray50 4263, 381 1076, 96 1056, 99 1071, 87 1060, 99 -0.0305 0.0533 0.567 0.2465 0.97 0.874 1.08 0.06 0.149 0.687 0.1629 1.06 0.793 1.42 -0.0837 0.153 0.585 0.2328 0.92 0.681 1.24 0.0352 0.149 0.813 0.08987 1.04 0.773 1.39 PRS_PLINK_1.99526231496888e.06 1001 Foreign body injury Both 822 8739 18 injuries & poisonings gray50 8739, 822 2182, 167 2194, 214 2192, 222 2168, 219 0.0755 0.0356 0.0341 1.467 1.08 1.01 1.16 0.239 0.107 0.0256 1.591 1.27 1.03 1.57 0.278 0.106 0.00886 2.053 1.32 1.07 1.63 0.277 0.107 0.00964 2.016 1.32 1.07 1.63 PRS_PLINK_1.99526231496888e.06 1002 Symptoms concerning nutrition, metabolism, and development Both 3520 39155 18 injuries & poisonings gray50 39155, 3520 9813, 853 9824, 841 9722, 930 9784, 895 0.0377 0.0174 0.0306 1.514 1.04 1 1.07 -0.015 0.0506 0.767 0.1153 0.985 0.892 1.09 0.0979 0.0495 0.048 1.319 1.1 1 1.22 0.0551 0.05 0.27 0.5679 1.06 0.958 1.17 PRS_PLINK_1.99526231496888e.06 1004 Other signs and symptoms involving emotional state Both 191 2193 18 injuries & poisonings gray50 2193, 191 556, 51 542, 43 548, 42 547, 54 0.0256 0.0738 0.729 0.1374 1.03 0.888 1.19 -0.151 0.213 0.479 0.3201 0.86 0.566 1.31 -0.184 0.215 0.391 0.4074 0.832 0.546 1.27 0.0783 0.202 0.698 0.1564 1.08 0.729 1.61 PRS_PLINK_1.99526231496888e.06 1005 Other symptoms Both 863 10313 18 injuries & poisonings gray50 10313, 863 2596, 218 2561, 223 2588, 211 2563, 211 0.0181 0.035 0.604 0.2187 1.02 0.951 1.09 0.0423 0.099 0.67 0.1742 1.04 0.859 1.27 -0.0305 0.1 0.761 0.1186 0.97 0.797 1.18 -0.0234 0.1 0.816 0.0885 0.977 0.802 1.19 PRS_PLINK_1.99526231496888e.06 1006 Crushing injury Both 176 1821 18 injuries & poisonings gray50 1821, 176 456, 46 455, 47 459, 49 451, 34 -0.068 0.0795 0.393 0.4057 0.934 0.799 1.09 4.15e-05 0.216 1 6.667e-05 1 0.655 1.53 0.0901 0.214 0.673 0.172 1.09 0.72 1.66 -0.279 0.232 0.228 0.6413 0.756 0.48 1.19 PRS_PLINK_1.99526231496888e.06 1007 Injury to blood vessels Both 178 1913 18 injuries & poisonings gray50 1913, 178 479, 47 480, 44 478, 38 476, 48 -0.0576 0.0766 0.452 0.3448 0.944 0.812 1.1 -0.0625 0.217 0.773 0.1117 0.939 0.614 1.44 -0.203 0.224 0.364 0.4388 0.816 0.527 1.27 0.0135 0.212 0.949 0.02262 1.01 0.669 1.54 PRS_PLINK_1.99526231496888e.06 1008 Crushing or internal injury to organs Both 707 7313 18 injuries & poisonings gray50 7313, 707 1828, 181 1834, 170 1824, 201 1825, 155 -0.0464 0.0393 0.237 0.6244 0.955 0.884 1.03 -0.0656 0.111 0.556 0.255 0.936 0.753 1.17 0.118 0.107 0.271 0.5663 1.13 0.912 1.39 -0.15 0.114 0.188 0.7248 0.861 0.688 1.08 PRS_PLINK_1.99526231496888e.06 1009 Injury, NOS Both 5883 62296 18 injuries & poisonings gray50 62296, 5883 15577, 1312 15639, 1541 15743, 1558 15318, 1471 0.0343 0.0135 0.0114 1.944 1.03 1.01 1.06 0.157 0.0392 6.25e-05 4.204 1.17 1.08 1.26 0.162 0.0391 3.66e-05 4.437 1.18 1.09 1.27 0.134 0.0397 0.000724 3.141 1.14 1.06 1.24 PRS_PLINK_1.99526231496888e.06 1010 Other tests Both 3788 42750 18 injuries & poisonings gray50 42750, 3788 10757, 996 10616, 910 10713, 969 10654, 912 -0.0131 0.0169 0.44 0.3565 0.987 0.955 1.02 -0.0773 0.0478 0.106 0.9745 0.926 0.843 1.02 -0.0215 0.0471 0.649 0.1879 0.979 0.892 1.07 -0.0789 0.0479 0.0993 1.003 0.924 0.841 1.02 PRS_PLINK_1.99526231496888e.06 1011 Complications of surgical and medical procedures Both 5585 64404 18 injuries & poisonings gray50 64404, 5585 16093, 1410 16113, 1379 16090, 1380 16085, 1414 0.0124 0.0138 0.369 0.4327 1.01 0.985 1.04 -0.0212 0.0395 0.591 0.2286 0.979 0.906 1.06 -0.018 0.0395 0.648 0.1884 0.982 0.909 1.06 0.00729 0.0393 0.853 0.06909 1.01 0.933 1.09 PRS_PLINK_1.99526231496888e.06 1012 Late effect Both 76 764 18 injuries & poisonings gray50 764, 76 191, 13 191, 21 193, 24 188, 18 0.0898 0.118 0.446 0.3509 1.09 0.868 1.38 0.479 0.36 0.184 0.7358 1.61 0.797 3.27 0.601 0.347 0.0831 1.081 1.82 0.924 3.6 0.294 0.364 0.419 0.3777 1.34 0.658 2.74 PRS_PLINK_1.99526231496888e.06 1013 Asphyxia and hypoxemia Both 199 2244 18 injuries & poisonings gray50 2244, 199 564, 40 555, 59 570, 47 552, 53 0.0617 0.0718 0.39 0.4088 1.06 0.924 1.22 0.397 0.211 0.0599 1.223 1.49 0.984 2.25 0.134 0.22 0.543 0.2653 1.14 0.743 1.76 0.313 0.215 0.146 0.8361 1.37 0.897 2.09 PRS_PLINK_1.99526231496888e.06 1014 Effects of heat, cold and air pressure Both 53 489 18 injuries & poisonings gray50 489, 53 126, 14 119, 9 124, 12 120, 18 0.11 0.137 0.42 0.3772 1.12 0.854 1.46 -0.377 0.426 0.376 0.4243 0.686 0.297 1.58 -0.0441 0.406 0.913 0.03932 0.957 0.432 2.12 0.365 0.374 0.329 0.4829 1.44 0.693 2.99 PRS_PLINK_1.99526231496888e.06 1015 Effects of other external causes Both 2671 31277 18 injuries & poisonings gray50 31277, 2671 7857, 699 7796, 690 7934, 651 7681, 630 -0.0223 0.0205 0.276 0.5596 0.978 0.94 1.02 -0.00161 0.056 0.977 0.01008 0.998 0.895 1.11 -0.0773 0.0567 0.173 0.7625 0.926 0.828 1.03 -0.0744 0.0573 0.194 0.7115 0.928 0.83 1.04 PRS_PLINK_1.99526231496888e.06 1019 Other ill-defined and unknown causes of morbidity and mortality Both 10738 116961 18 injuries & poisonings gray50 116961, 10738 29274, 2676 29290, 2628 29121, 2720 29238, 2711 0.00977 0.0101 0.333 0.4777 1.01 0.99 1.03 -0.0178 0.0287 0.535 0.2715 0.982 0.929 1.04 0.0241 0.0285 0.397 0.4013 1.02 0.969 1.08 0.0196 0.0285 0.492 0.308 1.02 0.964 1.08 PRS_PLINK_1.99526231496888e.06