phewas_code phewas_string sex MatchedCases MatchedControls groupnum group color N N_Q1 N_Q2 N_Q3 N_Q4 PRS_BETA PRS_SEBETA PRS_P PRS_LOG10P PRS_OR PRS_CI1 PRS_CI2 Q1Q2_BETA Q1Q2_SEBETA Q1Q2_P Q1Q2_LOG10P Q1Q2_OR Q1Q2_CI1 Q1Q2_CI2 Q1Q3_BETA Q1Q3_SEBETA Q1Q3_P Q1Q3_LOG10P Q1Q3_OR Q1Q3_CI1 Q1Q3_CI2 Q1Q4_BETA Q1Q4_SEBETA Q1Q4_P Q1Q4_LOG10P Q1Q4_OR Q1Q4_CI1 Q1Q4_CI2 predictor 008 Intestinal infection Both 7 45 1 infectious diseases blue 45, 7 12, 3 11, 1 11, 2 11, 1 -0.415 0.466 0.373 0.429 0.66 0.191 1.5 -2.08 2.03 0.306 0.514 0.125 1.4e-07 8.12 0.52 1.58 0.742 0.13 1.68 0.0594 43.6 0.0121 1.24 0.992 0.003 1.01 0.0844 153 PRS_PLINK_0.000251188643150958 008.5 Bacterial enteritis Both 2 16 1 infectious diseases blue 16, 2 4, 1 4, 0 4, 1 4, 0 -0.45 1.41 0.75 0.125 0.638 0.0132 23.9 0.0221 17.6 0.999 0 1.02 0.362 3.65 -2.34 15.8 0.882 0.054 0.0961 0.00913 0.375 0.427 165 0.998 0.001 1.53 0.127 8.26 PRS_PLINK_0.000251188643150958 008.52 Intestinal infection due to C. difficile Both 1 11 1 infectious diseases blue 11, 1 3, 0 3, 0 2, 0 3, 1 0.444 1.81 0.807 0.093 1.56 0.0858 31.2 0.00402 16.3 1 0 1 0.928 1.1 PRS_PLINK_0.000251188643150958 008.6 Viral Enteritis Both 1 13 1 infectious diseases blue 13, 1 4, 1 3, 0 3, 0 3, 0 0.0468 1.96 0.981 0.008 1.05 0.0153 243 0.456 787 1 0 1.58 0.141 6.33 0.0212 244 1 0 1.02 0.621 1.33 0.201 508 1 0 1.22 0.856 1.46 PRS_PLINK_0.000251188643150958 010 Tuberculosis Both 2 3 1 infectious diseases blue 3, 2 1, 1 1, 0 0, 1 1, 0 2.85 9770 1 0 17.2 7.05e-25 8.28e+28 0.0035 56.2 1 0 1 0.953 1.03 0.0226 4900 1 0 1.02 0.474 1.42 0.00841 58.6 1 0 1.01 0.932 1.07 PRS_PLINK_0.000251188643150958 031 Diseases due to other mycobacteria Both 1 2 1 infectious diseases blue 2, 1 1, 1 1, 0 1, 1 1, 0 0.0522 3400 1 0 1.05 0.374 1.09 0.0352 158 1 0 1.04 0.944 1.18 PRS_PLINK_0.000251188643150958 038 Septicemia Both 1 34 1 infectious diseases blue 34, 1 9, 0 8, 1 8, 0 9, 0 -0.255 0.764 0.738 0.132 0.775 0.0266 4.37 0.513 1.49 0.731 0.136 1.67 0.0262 170 PRS_PLINK_0.000251188643150958 038.1 Gram negative septicemia Both 1 9 1 infectious diseases blue 9, 1 3, 0 2, 1 2, 0 2, 0 -0.171 2.33 0.941 0.026 0.843 0.0258 41.5 0.0722 3880 1 0 1.07 0.304 3.21 PRS_PLINK_0.000251188643150958 038.2 Gram positive septicemia Both 0 3 1 infectious diseases blue 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 038.3 Bacteremia Both 0 18 1 infectious diseases blue 18, 0 5 4 4 5 PRS_PLINK_0.000251188643150958 041 Bacterial infection NOS Both 4 52 1 infectious diseases blue 52, 4 12, 3 13, 1 13, 0 13, 0 -0.499 0.5 0.318 0.497 0.607 0.156 1.65 -0.0921 1.06 0.931 0.031 0.912 0.0982 8.31 -0.87 1.36 0.521 0.283 0.419 0.00279 4.71 -0.241 1.71 0.888 0.052 0.786 0.00812 25100 PRS_PLINK_0.000251188643150958 041.1 Staphylococcus infections Both 2 26 1 infectious diseases blue 26, 2 7, 2 6, 0 6, 0 7, 0 -0.255 0.645 0.692 0.16 0.775 0.0585 3.96 -0.361 2.08 0.862 0.064 0.697 0.000261 30.4 0.246 1.77 0.89 0.051 1.28 0.012 396 -1.17 2.57 0.648 0.188 0.311 0.000123 289 PRS_PLINK_0.000251188643150958 041.11 Methicillin sensitive Staphylococcus aureus Both 2 16 1 infectious diseases blue 16, 2 4, 2 4, 0 4, 0 4, 0 -0.342 0.702 0.626 0.204 0.71 0.147 3.16 1.02 3.63 0.778 0.109 2.79 0.00886 942 -0.0823 2.48 0.974 0.012 0.921 0.0245 43.8 -1.41 9.76 0.885 0.053 0.245 0.228 0.261 PRS_PLINK_0.000251188643150958 041.12 Methicillin resistant Staphylococcus aureus Both 2 14 1 infectious diseases blue 14, 2 4, 2 3, 0 3, 0 4, 0 -0.0566 1 0.955 0.02 0.945 0.131 13.1 -0.285 33.5 0.993 0.003 0.752 0.00354 154 0.616 41.7 0.988 0.005 1.85 1.74 108 1.37 9.96 0.891 0.05 3.93 0.00178 4.43 PRS_PLINK_0.000251188643150958 041.2 Streptococcus infection Both 2 17 1 infectious diseases blue 17, 2 5, 0 4, 2 4, 0 4, 0 -0.0746 0.792 0.925 0.034 0.928 0.0728 4.23 0.904 2.33 0.698 0.156 2.47 0.0182 231 PRS_PLINK_0.000251188643150958 041.21 Rheumatic fever / chorea Both 0 1 1 infectious diseases blue 1, 0 PRS_PLINK_0.000251188643150958 041.4 E. coli Both 2 12 1 infectious diseases blue 12, 2 3, 0 3, 1 3, 1 3, 0 0.53 1.56 0.735 0.134 1.7 0.138 32.3 0.232 3840 1 0 1.26 0.559 1.68 0.174 2180 1 0 1.19 0.216 5.57 PRS_PLINK_0.000251188643150958 041.8 H. pylori Both 0 2 1 infectious diseases blue 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 041.9 Infection with drug-resistant microorganisms Both 0 5 1 infectious diseases blue 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 053 Herpes zoster Both 3 22 1 infectious diseases blue 22, 3 6, 1 5, 0 5, 0 6, 2 0.181 0.777 0.816 0.088 1.2 0.261 7.05 0.942 5.36 0.86 0.065 2.57 0.000901 3.09 -1.88 8.61 0.827 0.082 0.153 0.134 0.176 1.3 2.71 0.63 0.2 3.68 3.27 4.06 PRS_PLINK_0.000251188643150958 053.1 Herpes zoster with nervous system complications Both 1 3 1 infectious diseases blue 3, 1 1, 1 1, 0 1, 0 1, 1 -21.3 116000 1 0 5.73e-10 2.56e-40 2.53e+20 0.603 18100 1 0 1.83 0.237 2.87 -0.00851 56.1 1 0 0.992 0.793 9.95 PRS_PLINK_0.000251188643150958 054 Herpes simplex Both 3 22 1 infectious diseases blue 22, 3 5, 1 5, 0 5, 0 6, 2 0.808 0.732 0.269 0.57 2.24 0.46 35.9 0.829 7.86 0.916 0.038 2.29 0.00498 743 7.26 139 0.958 0.018 1430 596 3200 0.863 2.37 0.716 0.145 2.37 0.0721 6730 PRS_PLINK_0.000251188643150958 070 Viral hepatitis Both 1 8 1 infectious diseases blue 8, 1 2, 0 2, 0 2, 0 2, 1 0.264 282 0.999 0 1.3 1.08 1.96 0.219 4140 1 0 1.25 0.649 2.32 PRS_PLINK_0.000251188643150958 070.2 Viral hepatitis B Both 1 1 1 infectious diseases blue 1, 1 -0.00489 133 1 0 0.995 0.779 1.13 PRS_PLINK_0.000251188643150958 070.3 Viral hepatitis C Both 0 7 1 infectious diseases blue 7, 0 2 2 1 2 PRS_PLINK_0.000251188643150958 070.4 Chronic hepatitis Both 0 1 1 infectious diseases blue 1, 0 PRS_PLINK_0.000251188643150958 070.9 Hepatitis NOS Both 3 9 1 infectious diseases blue 9, 3 3, 1 2, 0 2, 1 2, 1 -0.507 2.42 0.834 0.079 0.602 0.566 0.691 -0.389 1900 1 0 0.678 0.666 1.6 0.233 460 1 0 1.26 0.107 13.5 0.0479 970 1 0 1.05 0.000612 1240 PRS_PLINK_0.000251188643150958 071 Human immunodeficiency virus [HIV] disease Both 0 2 1 infectious diseases blue 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 071.1 HIV infection, symptomatic Both 0 2 1 infectious diseases blue 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 078 Viral warts & HPV Both 10 34 1 infectious diseases blue 34, 10 8, 2 8, 3 8, 4 9, 1 0.113 0.441 0.798 0.098 1.12 0.495 2.63 0.211 2.3 0.927 0.033 1.23 0.00508 169 0.629 1.47 0.669 0.175 1.88 0.0552 37.5 0.0515 1.29 0.968 0.014 1.05 0.0828 10.2 PRS_PLINK_0.000251188643150958 079 Viral infection Both 13 38 1 infectious diseases blue 38, 13 9, 4 9, 4 9, 1 10, 4 0.0996 0.348 0.775 0.111 1.1 0.589 2.15 0.159 1.14 0.889 0.051 1.17 0.141 10.1 -0.0765 1.41 0.957 0.019 0.926 0.0476 23.6 -0.279 1.13 0.804 0.095 0.757 0.092 5.98 PRS_PLINK_0.000251188643150958 079.1 Varicella infection Both 8 32 1 infectious diseases blue 32, 8 7, 3 8, 2 8, 0 8, 3 0.243 0.533 0.648 0.189 1.28 0.496 4.05 -0.521 1.51 0.729 0.137 0.594 0.0154 7.13 -1.63 1.96 0.404 0.393 0.196 0.000256 5.37 -0.8 1.51 0.596 0.225 0.449 0.0234 6.6 PRS_PLINK_0.000251188643150958 079.2 Infectious mononucleosis Both 0 4 1 infectious diseases blue 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 079.9 Viremia, NOS Both 2 12 1 infectious diseases blue 12, 2 2, 1 3, 1 3, 0 3, 0 -0.0855 0.654 0.896 0.048 0.918 0.257 2.77 -1.62 9800 1 0 0.197 2.83e-07 14600 0.696 1900 1 0 2.01 0.0588 2.32 0.784 1940 1 0 2.19 8.84e-10 1.92e+09 PRS_PLINK_0.000251188643150958 080 Postoperative infection Both 0 29 1 infectious diseases blue 29, 0 8 7 7 7 PRS_PLINK_0.000251188643150958 081 Infection/inflammation of internal prosthetic device; implant; and graft Both 3 15 1 infectious diseases blue 15, 3 4, 1 4, 0 3, 2 4, 0 0.699 1.6 0.662 0.179 2.01 0.0428 40.8 0.572 26.6 0.983 0.008 1.77 0.0338 1.89 0.293 2.43 0.904 0.044 1.34 1.23 1.42 0.284 221 0.999 0 1.33 0.347 2.47 PRS_PLINK_0.000251188643150958 090 Sexually transmitted infections (not HIV or hepatitis) Both 2 19 1 infectious diseases blue 19, 2 4, 0 5, 1 4, 0 5, 1 -0.0254 0.801 0.975 0.011 0.975 0.0631 18.5 3.11 9.26 0.737 0.133 22.5 17.9 28.2 1.53e-11 45.5 1 0 1 0.0015 667 PRS_PLINK_0.000251188643150958 110 Dermatophytosis / Dermatomycosis Both 13 33 1 infectious diseases blue 33, 13 9, 2 8, 5 8, 2 8, 4 -0.0463 0.46 0.92 0.036 0.955 0.373 2.38 0.8 1.64 0.626 0.204 2.22 0.0969 1170 -0.4 2.32 0.863 0.064 0.67 0.000477 127 1.86 1.81 0.304 0.518 6.45 0.215 10500 PRS_PLINK_0.000251188643150958 110.1 Dermatophytosis Both 13 31 1 infectious diseases blue 31, 13 8, 2 8, 5 7, 1 8, 5 0.0555 0.473 0.907 0.043 1.06 0.418 2.79 0.633 1.66 0.703 0.153 1.88 0.0997 251 -0.352 2.41 0.884 0.054 0.703 0.00138 707 0.689 1.29 0.593 0.227 1.99 0.141 95.2 PRS_PLINK_0.000251188643150958 110.11 Dermatophytosis of nail Both 9 18 1 infectious diseases blue 18, 9 5, 2 4, 2 4, 1 5, 4 -0.165 0.867 0.849 0.071 0.848 0.0892 4.14 1.57 4.4 0.722 0.141 4.79 0.00752 4220 0.0818 1860 1 0 1.09 0.7 1.38 -0.974 2.89 0.736 0.133 0.378 0.00165 918000 PRS_PLINK_0.000251188643150958 110.12 Althete's foot Both 4 15 1 infectious diseases blue 15, 4 4, 0 4, 1 3, 1 4, 2 1.04 0.973 0.284 0.546 2.83 0.551 26.2 0.225 2210 1 0 1.25 0.514 2.08 0.5 50.7 0.992 0.003 1.65 0.000502 6180 0.0827 465 1 0 1.09 0.684 1.82 PRS_PLINK_0.000251188643150958 110.13 Dermatophytosis of the body Both 2 16 1 infectious diseases blue 16, 2 4, 1 4, 0 4, 1 4, 0 -0.599 1.31 0.647 0.189 0.549 0.00545 5.02 0.962 96.4 0.992 0.003 2.62 1.35e-09 4.05e+09 0.728 340 0.998 0.001 2.07 1.04 1.66 0.627 383 0.999 0.001 1.87 1.59 2.21 PRS_PLINK_0.000251188643150958 110.2 Dermatomycoses Both 2 7 1 infectious diseases blue 7, 2 2, 0 2, 1 1, 0 2, 1 1.48 30.3 0.961 0.017 4.38 0.0125 1610 0.0338 7460 1 0 1.03 0.226 3.62 -0.464 16200 1 0 0.629 0.505 2890 PRS_PLINK_0.000251188643150958 112 Candidiasis Both 7 35 1 infectious diseases blue 35, 7 8, 2 9, 2 8, 2 9, 1 -0.103 0.657 0.876 0.058 0.902 0.226 4.96 -1.69 1.67 0.31 0.509 0.184 7.54e-07 3.04 0.843 1.42 0.553 0.257 2.32 0.185 45.1 -0.0382 1.67 0.982 0.008 0.962 0.00477 22.7 PRS_PLINK_0.000251188643150958 112.3 Candidiasis of skin and nails Both 0 4 1 infectious diseases blue 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 117 Mycoses Both 2 4 1 infectious diseases blue 4, 2 1, 2 1, 0 1, 0 1, 0 0.091 1940 1 0 1.1 0.686 1.28 -0.0337 8550 1 0 0.967 0.397 24200000 1.13 26000 1 0 3.09 0.0191 10700 -4.75e-06 3280 1 0 1 0.194 6.24 PRS_PLINK_0.000251188643150958 117.4 Aspergillosis Both 2 1 1 infectious diseases blue 1, 2 0.0212 1120 1 0 1.02 0.968 1.04 PRS_PLINK_0.000251188643150958 130 Spirochetal infection Both 1 3 1 infectious diseases blue 3, 1 1, 0 1, 0 0, 1 1, 0 0.0324 3150 1 0 1.03 0.598 2.37 -0.0183 4.93 0.997 0.001 0.982 0.928 1.06 PRS_PLINK_0.000251188643150958 130.1 Lyme disease Both 0 2 1 infectious diseases blue 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 131 Protozoan infection Both 0 2 1 infectious diseases blue 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 134 Helminthiases Both 1 1 1 infectious diseases blue 1, 1 0.00659 16.6 1 0 1.01 0.967 1.05 PRS_PLINK_0.000251188643150958 134.1 Intestinal helminthiases Both 1 0 1 infectious diseases blue 0, 1 PRS_PLINK_0.000251188643150958 136 Other infectious and parasitic diseases Both 6 41 1 infectious diseases blue 41, 6 10, 1 10, 2 10, 3 10, 0 0.337 0.497 0.497 0.303 1.4 0.376 3.86 1.59 1.77 0.37 0.432 4.91 0.247 3730000 2.95 2.22 0.184 0.736 19.2 0.474 155000 -0.515 1.69 0.761 0.118 0.598 0.000276 10.5 PRS_PLINK_0.000251188643150958 145 Cancer of mouth Both 1 10 2 neoplasms darkcyan 10, 1 3, 1 2, 0 2, 0 3, 0 0.0723 1.88 0.969 0.014 1.08 0.0226 29.4 -0.204 1170 1 0 0.815 0.359 1.25 0.00104 11.1 1 0 1 0.975 1.02 -0.251 3200 1 0 0.778 0.768 1.67 PRS_PLINK_0.000251188643150958 145.1 Cancer of lip Both 0 1 2 neoplasms darkcyan 1, 0 PRS_PLINK_0.000251188643150958 145.2 Cancer of tongue Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 145.3 Cancer of major salivary glands Both 1 2 2 neoplasms darkcyan 2, 1 1, 1 1, 0 1, 1 1, 0 -0.129 3640 1 0 0.879 0.808 1.53 -0.556 3660 1 0 0.574 0.5 1.04 PRS_PLINK_0.000251188643150958 145.4 Cancer of the gums Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 149 Cancer of larynx, pharynx, nasal cavities Both 1 10 2 neoplasms darkcyan 10, 1 3, 1 2, 0 2, 0 3, 0 -0.036 3.39 0.992 0.004 0.965 0.000581 708 0.0821 157 1 0 1.09 0.858 1.22 -0.154 1450 1 0 0.857 0.75 2.07 0.0063 832 1 0 1.01 0.72 1.6 PRS_PLINK_0.000251188643150958 149.1 Cancer of oropharynx Both 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 149.2 Cancer of nasopharynx Both 0 1 2 neoplasms darkcyan 1, 0 PRS_PLINK_0.000251188643150958 149.4 Cancer of larynx Both 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 149.5 Hx of malignant neoplasm of oral cavity and pharynx Both 1 3 2 neoplasms darkcyan 3, 1 1, 1 1, 0 1, 0 1, 1 0.115 5730 1 0 1.12 0.659 3.89 0.0104 71.9 1 0 1.01 0.91 1.53 -0.0157 59.7 1 0 0.984 0.934 1.16 PRS_PLINK_0.000251188643150958 149.9 Cancer of of nasal cavities Both 0 1 2 neoplasms darkcyan 1, 0 PRS_PLINK_0.000251188643150958 150 Cancer of esophagus Both 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 151 Cancer of stomach Both 1 1 2 neoplasms darkcyan 1, 1 0.00205 60.6 1 0 1 0.962 1.04 PRS_PLINK_0.000251188643150958 153 Colorectal cancer Both 0 9 2 neoplasms darkcyan 9, 0 3 2 2 2 PRS_PLINK_0.000251188643150958 153.2 Colon cancer Both 0 6 2 neoplasms darkcyan 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 153.3 Malignant neoplasm of rectum, rectosigmoid junction, and anus Both 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 155 Cancer of liver and intrahepatic bile duct Both 0 4 2 neoplasms darkcyan 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 155.1 Malignant neoplasm of liver, primary Both 0 4 2 neoplasms darkcyan 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 157 Pancreatic cancer Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 158 Neoplasm of unspecified nature of digestive system Both 2 10 2 neoplasms darkcyan 10, 2 3, 0 2, 1 2, 0 3, 1 1.47 1.64 0.37 0.432 4.37 0.45 147 -0.227 1970 1 0 0.797 0.744 3.1 -0.0395 912 1 0 0.961 0.857 1.52 PRS_PLINK_0.000251188643150958 159 Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum Both 1 9 2 neoplasms darkcyan 9, 1 3, 1 2, 0 2, 0 2, 0 0.985 3 0.743 0.129 2.68 2.53 2.84 -2.44 363 0.995 0.002 0.0869 9.71e-06 61.9 0.92 10200 1 0 2.51 0.000428 8800 -0.973 4390000 1 0 0.378 0.00139 87.7 PRS_PLINK_0.000251188643150958 159.2 Malignant neoplasm of small intestine, including duodenum Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 159.3 Malignant neoplasm of gallbladder and extrahepatic bile ducts Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 159.4 Malignant neoplasm of retroperitoneum and peritoneum Both 0 1 2 neoplasms darkcyan 1, 0 PRS_PLINK_0.000251188643150958 165 Cancer within the respiratory system Both 0 12 2 neoplasms darkcyan 12, 0 3 3 3 3 PRS_PLINK_0.000251188643150958 165.1 Cancer of bronchus; lung Both 0 10 2 neoplasms darkcyan 10, 0 3 2 2 3 PRS_PLINK_0.000251188643150958 170 Cancer of bone and connective tissue Both 0 15 2 neoplasms darkcyan 15, 0 4 4 3 4 PRS_PLINK_0.000251188643150958 170.1 Bone cancer Both 0 12 2 neoplasms darkcyan 12, 0 3 3 3 3 PRS_PLINK_0.000251188643150958 170.2 Cancer of connective tissue Both 0 5 2 neoplasms darkcyan 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 172 Skin cancer Both 5 43 2 neoplasms darkcyan 43, 5 10, 1 11, 1 10, 1 11, 2 -0.585 0.637 0.359 0.445 0.557 0.133 2.38 -0.17 1.25 0.892 0.049 0.844 0.076 7.94 -1.64 1.85 0.375 0.426 0.193 0.000112 4.74 -0.865 2.11 0.682 0.166 0.421 0.00108 20.1 PRS_PLINK_0.000251188643150958 172.1 Melanomas of skin, dx or hx Both 4 33 2 neoplasms darkcyan 33, 4 9, 1 8, 0 8, 3 8, 0 -0.511 0.686 0.456 0.341 0.6 0.0876 2.29 -0.0354 1.57 0.982 0.008 0.965 0.0327 158 0.343 1.32 0.795 0.1 1.41 0.0709 15.2 0.0638 2.36 0.978 0.009 1.07 1.62e-05 498 PRS_PLINK_0.000251188643150958 172.11 Melanomas of skin Both 1 19 2 neoplasms darkcyan 19, 1 5, 0 5, 0 4, 0 5, 1 0.802 1.24 0.519 0.285 2.23 0.143 52.6 0.983 2.76 0.721 0.142 2.67 0.057 197 PRS_PLINK_0.000251188643150958 172.2 Other non-epithelial cancer of skin Both 4 37 2 neoplasms darkcyan 37, 4 10, 1 9, 1 9, 2 9, 0 -1.07 0.789 0.177 0.753 0.344 0.0359 1.63 0.281 1.62 0.862 0.064 1.32 0.0642 79.4 -1.34 1.93 0.486 0.313 0.261 0.00119 7.04 -0.747 2.57 0.772 0.113 0.474 8e-05 420 PRS_PLINK_0.000251188643150958 172.21 Basal cell carcinoma Both 4 22 2 neoplasms darkcyan 22, 4 6, 1 5, 2 5, 0 6, 1 -0.942 0.818 0.25 0.603 0.39 0.0343 1.69 2.27 3.39 0.502 0.299 9.71 0.0414 12.1 -0.762 1.88 0.686 0.164 0.467 0.0138 9.67 -1.65 4.35 0.705 0.152 0.193 0.000123 49100 PRS_PLINK_0.000251188643150958 172.22 Squamous cell carcinoma Both 0 12 2 neoplasms darkcyan 12, 0 3 3 3 3 PRS_PLINK_0.000251188643150958 172.3 Carcinoma in situ of skin Both 0 11 2 neoplasms darkcyan 11, 0 3 3 2 3 PRS_PLINK_0.000251188643150958 173 Neoplasm of uncertain behavior of skin Both 1 26 2 neoplasms darkcyan 26, 1 7, 0 6, 1 6, 0 7, 0 0.14 0.98 0.886 0.052 1.15 0.07 22.3 0.471 3.84 0.902 0.045 1.6 7.96e-06 167000 PRS_PLINK_0.000251188643150958 174 Breast cancer Both 3 18 2 neoplasms darkcyan 18, 3 4, 0 4, 2 4, 0 5, 1 -0.618 0.903 0.494 0.307 0.539 0.00135 3.55 4.69 9.43 0.619 0.208 108 3.02e-06 9.87e+10 -1.01 20.8 0.961 0.017 0.363 1.15e-10 7.06e+08 PRS_PLINK_0.000251188643150958 174.1 Breast cancer [female] Female 3 19 2 neoplasms darkcyan 19, 3 4, 0 5, 2 4, 0 5, 1 -0.538 0.842 0.523 0.282 0.584 0.00583 3.02 0.469 4.72 0.921 0.036 1.6 0.000657 470000 -1.63 30 0.957 0.019 0.195 1.66e-10 2.5e+08 PRS_PLINK_0.000251188643150958 174.11 Malignant neoplasm of female breast Female 3 18 2 neoplasms darkcyan 18, 3 4, 0 4, 2 4, 0 5, 1 -0.618 0.903 0.494 0.307 0.539 0.00135 3.55 4.69 9.43 0.619 0.208 108 3.02e-06 9.87e+10 -1.01 20.8 0.961 0.017 0.363 1.15e-10 7.06e+08 PRS_PLINK_0.000251188643150958 174.3 Neoplasm of uncertain behavior of breast Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 175 Acquired absence of breast Female 1 5 2 neoplasms darkcyan 5, 1 2, 0 1, 0 1, 1 1, 0 -0.0825 100 0.999 0 0.921 0.652 1.08 -0.33 6430 1 0 0.719 0.0528 2.38 PRS_PLINK_0.000251188643150958 180 Cervical cancer and dysplasia Female 2 11 2 neoplasms darkcyan 11, 2 2, 0 3, 0 2, 2 3, 0 -0.851 1.41 0.547 0.262 0.427 0.00665 5.01 0.0182 522 1 0 1.02 0.481 1.5 PRS_PLINK_0.000251188643150958 180.1 Cervical cancer Female 1 4 2 neoplasms darkcyan 4, 1 1, 0 1, 1 1, 0 1, 0 -0.0309 9170 1 0 0.97 0.192 3.39 -0.242 9170 1 0 0.785 0.476 1.68 PRS_PLINK_0.000251188643150958 180.3 Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia] Female 1 11 2 neoplasms darkcyan 11, 1 2, 0 3, 0 2, 1 3, 0 0.28 2.49 0.911 0.041 1.32 0.00325 432 -0.112 1580 1 0 0.894 1.85e-22 8.53e+16 PRS_PLINK_0.000251188643150958 182 Malignant neoplasm of uterus Female 0 5 2 neoplasms darkcyan 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 184 Cancer of other female genital organs Female 0 6 2 neoplasms darkcyan 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 184.1 Malignant neoplasm of ovary and other uterine adnexa Female 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 184.11 Malignant neoplasm of ovary Female 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 184.2 Cancer of other female genital organs (excluding uterus and ovary) Female 0 5 2 neoplasms darkcyan 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 185 Cancer of prostate Male 0 9 2 neoplasms darkcyan 9, 0 3 2 2 2 PRS_PLINK_0.000251188643150958 187 Cancer of other male genital organs Male 1 2 2 neoplasms darkcyan 2, 1 1, 1 1, 0 1, 1 1, 0 0.737 4390 1 0 2.09 0.129 276 9.41 422000 1 0 12200 2.47e-09 1.21e+15 PRS_PLINK_0.000251188643150958 187.2 Malignant neoplasm of testis Male 1 3 2 neoplasms darkcyan 3, 1 1, 1 1, 0 1, 0 1, 1 -0.149 1070 1 0 0.862 0.418 1.21 -0.189 2620 1 0 0.828 0.204 1.6 -0.344 6750 1 0 0.709 0.552 2.45 PRS_PLINK_0.000251188643150958 187.8 Neoplasm of uncertain behavior of male genital organs Male 0 1 2 neoplasms darkcyan 1, 0 PRS_PLINK_0.000251188643150958 189 Cancer of urinary organs (incl. kidney and bladder) Both 0 19 2 neoplasms darkcyan 19, 0 5 5 4 5 PRS_PLINK_0.000251188643150958 189.1 Cancer of kidney and renal pelvis Both 0 10 2 neoplasms darkcyan 10, 0 3 2 2 3 PRS_PLINK_0.000251188643150958 189.11 Malignant neoplasm of kidney, except pelvis Both 0 9 2 neoplasms darkcyan 9, 0 3 2 2 2 PRS_PLINK_0.000251188643150958 189.12 Malignant neoplasm of renal pelvis Both 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 189.2 Cancer of bladder Both 0 10 2 neoplasms darkcyan 10, 0 3 2 2 3 PRS_PLINK_0.000251188643150958 189.21 Malignant neoplasm of bladder Both 0 8 2 neoplasms darkcyan 8, 0 2 2 2 2 PRS_PLINK_0.000251188643150958 189.4 Malignant neoplasm of other urinary organs Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 190 Cancer of eye Both 0 1 2 neoplasms darkcyan 1, 0 PRS_PLINK_0.000251188643150958 191 Manlignant and unknown neoplasms of brain and nervous system Both 0 10 2 neoplasms darkcyan 10, 0 3 2 2 3 PRS_PLINK_0.000251188643150958 191.1 Cancer of brain and nervous system Both 0 7 2 neoplasms darkcyan 7, 0 2 2 1 2 PRS_PLINK_0.000251188643150958 191.11 Cancer of brain Both 0 8 2 neoplasms darkcyan 8, 0 2 2 2 2 PRS_PLINK_0.000251188643150958 193 Thyroid cancer Both 0 16 2 neoplasms darkcyan 16, 0 4 4 4 4 PRS_PLINK_0.000251188643150958 194 Cancer of other endocrine glands Both 0 11 2 neoplasms darkcyan 11, 0 3 3 2 3 PRS_PLINK_0.000251188643150958 195 Cancer, suspected or other Both 9 48 2 neoplasms darkcyan 48, 9 11, 5 12, 1 12, 2 12, 1 -0.676 0.495 0.173 0.763 0.509 0.172 1.35 -2 1.35 0.139 0.857 0.136 0.000339 1.41 -2.18 1.6 0.172 0.765 0.113 0.000285 2.46 -0.3 1.57 0.849 0.071 0.741 0.00456 21.4 PRS_PLINK_0.000251188643150958 195.1 Malignant neoplasm, other Both 8 49 2 neoplasms darkcyan 49, 8 12, 4 12, 1 12, 2 12, 1 -0.682 0.49 0.164 0.785 0.506 0.174 1.33 -1.85 1.46 0.205 0.689 0.157 3.3e-07 2.08 -1.97 1.58 0.213 0.672 0.14 0.000588 2.77 -0.351 1.5 0.815 0.089 0.704 0.00586 23.5 PRS_PLINK_0.000251188643150958 195.3 Malignant neoplasm of head, face, and neck Both 0 8 2 neoplasms darkcyan 8, 0 2 2 2 2 PRS_PLINK_0.000251188643150958 196 Radiotherapy Both 0 14 2 neoplasms darkcyan 14, 0 4 3 3 4 PRS_PLINK_0.000251188643150958 197 Chemotherapy Both 1 33 2 neoplasms darkcyan 33, 1 8, 1 8, 0 8, 0 8, 0 -0.197 0.596 0.741 0.13 0.822 0.117 6.19 -0.087 2.21 0.969 0.014 0.917 0.00423 1470 0.319 1.58 0.84 0.076 1.38 0.0428 282 -1.88 2.19 0.391 0.408 0.153 0.000333 9.85 PRS_PLINK_0.000251188643150958 198 Secondary malignant neoplasm Both 0 31 2 neoplasms darkcyan 31, 0 7 8 7 8 PRS_PLINK_0.000251188643150958 198.1 Secondary malignancy of lymph nodes Both 0 25 2 neoplasms darkcyan 25, 0 7 6 6 6 PRS_PLINK_0.000251188643150958 198.2 Secondary malignancy of respiratory organs Both 0 6 2 neoplasms darkcyan 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 198.3 Secondary malignant neoplasm of digestive systems Both 0 5 2 neoplasms darkcyan 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 198.4 Secondary malignant neoplasm of liver Both 0 6 2 neoplasms darkcyan 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 198.5 Secondary malignancy of brain/spine Both 0 7 2 neoplasms darkcyan 7, 0 2 2 1 2 PRS_PLINK_0.000251188643150958 198.6 Secondary malignancy of bone Both 0 9 2 neoplasms darkcyan 9, 0 3 2 2 2 PRS_PLINK_0.000251188643150958 199 Neoplasm of uncertain behavior Both 4 48 2 neoplasms darkcyan 48, 4 11, 1 12, 1 12, 1 12, 1 0.491 0.656 0.454 0.343 1.63 0.292 11.5 -0.27 1.16 0.816 0.089 0.763 0.0498 8.4 0.262 1.47 0.859 0.066 1.3 0.00138 302 -0.237 1.3 0.856 0.068 0.789 0.0046 15.1 PRS_PLINK_0.000251188643150958 199.4 Neurofibromatosis Both 0 1 2 neoplasms darkcyan 1, 0 PRS_PLINK_0.000251188643150958 200 Myeloproliferative disease Both 0 13 2 neoplasms darkcyan 13, 0 4 3 3 3 PRS_PLINK_0.000251188643150958 200.1 Polycythemia vera Both 0 5 2 neoplasms darkcyan 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 201 Hodgkin's disease Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 202 Cancer of other lymphoid, histiocytic tissue Both 1 15 2 neoplasms darkcyan 15, 1 4, 1 4, 0 3, 0 4, 0 -0.36 1.2 0.763 0.117 0.698 0.000161 5.88 -3.07 102 0.976 0.011 0.0466 0.000732 0.365 -0.00687 2060000 1 0 0.993 0.863 2.24 -1.68 59.9 0.978 0.01 0.186 4.2e-06 0.643 PRS_PLINK_0.000251188643150958 202.2 Non-Hodgkins lymphoma Both 1 14 2 neoplasms darkcyan 14, 1 4, 1 3, 0 3, 0 4, 0 -0.354 1.18 0.764 0.117 0.702 0.0379 7.43 -0.00536 100 1 0 0.995 0.703 1.31 0.244 1090 1 0 1.28 0.00421 1590 -0.0321 6.37 0.996 0.002 0.968 0.905 5.19 PRS_PLINK_0.000251188643150958 202.21 Nodular lymphoma Both 1 8 2 neoplasms darkcyan 8, 1 2, 1 2, 0 2, 0 2, 0 -1.5 34.9 0.966 0.015 0.224 0.000862 56.7 -0.467 2630 1 0 0.627 0.145 2.53 -0.0616 890 1 0 0.94 0.716 1.26 -0.262 10600 1 0 0.77 0.509 8.64 PRS_PLINK_0.000251188643150958 202.22 Reticulosarcoma Both 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 202.24 Large cell lymphoma Both 0 1 2 neoplasms darkcyan 1, 0 PRS_PLINK_0.000251188643150958 204 Leukemia Both 1 10 2 neoplasms darkcyan 10, 1 3, 1 2, 0 2, 0 3, 0 -0.974 6.56 0.882 0.055 0.377 0.371 0.383 0.361 9440 1 0 1.43 0.506 1.8 0.04 1440 1 0 1.04 0.773 1.93 0.0338 2100 1 0 1.03 0.825 1.17 PRS_PLINK_0.000251188643150958 204.1 Lymphoid leukemia Both 0 5 2 neoplasms darkcyan 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 204.11 Lymphoid leukemia, acute Both 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 204.12 Lymphoid leukemia, chronic Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 204.2 Myeloid leukemia Both 0 7 2 neoplasms darkcyan 7, 0 2 2 1 2 PRS_PLINK_0.000251188643150958 204.21 Myeloid leukemia, acute Both 0 4 2 neoplasms darkcyan 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 204.4 Multiple myeloma Both 0 2 2 neoplasms darkcyan 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 208 Benign neoplasm of colon Both 24 38 2 neoplasms darkcyan 38, 24 9, 5 9, 8 9, 7 10, 4 -0.172 0.307 0.576 0.24 0.842 0.46 1.45 0.618 1.02 0.546 0.263 1.86 0.295 14.1 -0.583 1.18 0.62 0.208 0.558 0.0513 4.47 -1.18 1.19 0.321 0.493 0.307 0.0165 2.08 PRS_PLINK_0.000251188643150958 209 Neuroendocrine tumors Both 1 3 2 neoplasms darkcyan 3, 1 1, 1 1, 0 1, 0 1, 1 1.25 39700 1 0 3.49 0.0188 4.36 0.00176 37.4 1 0 1 0.974 1.03 0.00215 39 1 0 1 0.973 1.03 PRS_PLINK_0.000251188643150958 210 Benign neoplasm of lip, oral cavity, and pharynx Both 2 17 2 neoplasms darkcyan 17, 2 4, 1 4, 1 4, 0 4, 0 -0.404 0.998 0.686 0.164 0.668 0.0192 31.9 2.04e-11 10.9 1 0 1 0.00778 129 0.0753 3300000 1 0 1.08 0.325 3.48 -0.221 9310000 1 0 0.802 0.000164 313 PRS_PLINK_0.000251188643150958 211 Benign neoplasm of other parts of digestive system Both 19 43 2 neoplasms darkcyan 43, 19 10, 2 11, 8 10, 2 11, 7 0.199 0.313 0.526 0.279 1.22 0.681 2.2 3.57 1.73 0.0387 1.412 35.5 1.87 16200000 2.1 1.72 0.221 0.655 8.17 0.421 11100 1.46 1.21 0.229 0.639 4.29 0.56 69.2 PRS_PLINK_0.000251188643150958 212 Benign neoplasm of respiratory and intrathoracic organs Both 4 14 2 neoplasms darkcyan 14, 4 4, 2 3, 0 3, 1 4, 1 0.01 1.05 0.992 0.003 1.01 0.127 2.45 1.61 48.9 0.974 0.012 5.02 3.89 6.58 2.57 4.12 0.533 0.274 13.1 0.176 15.8 4.53 10.3 0.66 0.18 93.2 2.77e-05 2.2e+09 PRS_PLINK_0.000251188643150958 213 Benign neoplasm of bone and articular cartilage Both 0 14 2 neoplasms darkcyan 14, 0 3 3 3 4 PRS_PLINK_0.000251188643150958 214 Lipoma Both 3 12 2 neoplasms darkcyan 12, 3 3, 0 3, 1 3, 1 3, 1 -0.266 1.34 0.843 0.074 0.766 7.28e-05 13.5 -0.0272 3180 1 0 0.973 0.817 2.74 -0.143 4410 1 0 0.867 0.12 2.41 -0.0358 1780 1 0 0.965 0.915 1.13 PRS_PLINK_0.000251188643150958 214.1 Lipoma of skin and subcutaneous tissue Both 1 6 2 neoplasms darkcyan 6, 1 2, 0 1, 0 1, 1 2, 0 4.13e-05 1040 1 0 1 0.773 1.25 0.0422 7000 1 0 1.04 0.157 15.4 PRS_PLINK_0.000251188643150958 215 Other benign neoplasm of connective and other soft tissue Both 9 45 2 neoplasms darkcyan 45, 9 11, 1 11, 2 11, 3 11, 3 0.643 0.522 0.218 0.661 1.9 0.737 6.19 0.969 1.39 0.487 0.313 2.63 0.205 155 0.364 1.36 0.789 0.103 1.44 0.0273 134 0.26 1.6 0.871 0.06 1.3 0.0353 68 PRS_PLINK_0.000251188643150958 216 Benign neoplasm of skin Both 20 44 2 neoplasms darkcyan 44, 20 10, 5 11, 3 11, 2 11, 10 0.256 0.347 0.461 0.336 1.29 0.659 2.58 -0.262 1.14 0.818 0.087 0.77 0.0937 5.89 -0.831 1.6 0.604 0.219 0.436 0.00536 107 0.592 1.02 0.561 0.251 1.81 0.293 17.5 PRS_PLINK_0.000251188643150958 216.1 Screening for malignant neoplasms of the skin Both 0 5 2 neoplasms darkcyan 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 217 Vascular hamartomas and non-neoplastic nevi Both 1 16 2 neoplasms darkcyan 16, 1 3, 0 4, 0 4, 1 4, 0 -0.00999 1.12 0.993 0.003 0.99 0.0366 8.61 -0.00354 82 1 0 0.996 0.583 1.46 PRS_PLINK_0.000251188643150958 217.1 Nevus, non-neoplastic Both 1 15 2 neoplasms darkcyan 15, 1 3, 0 4, 0 3, 1 4, 0 -0.0244 1.13 0.983 0.008 0.976 0.0573 11.9 -0.0219 559 1 0 0.978 0.73 1.15 PRS_PLINK_0.000251188643150958 218 Benign neoplasm of uterus Female 10 18 2 neoplasms darkcyan 18, 10 4, 2 4, 3 4, 4 5, 1 0.237 0.556 0.67 0.174 1.27 0.498 4.65 -0.136 2.03 0.947 0.024 0.873 0.0299 22.3 -0.184 1.65 0.911 0.04 0.832 0.0344 15.5 -1.1 1.8 0.542 0.266 0.333 0.0135 4.67 PRS_PLINK_0.000251188643150958 218.1 Uterine leiomyoma Female 3 16 2 neoplasms darkcyan 16, 3 3, 1 4, 0 4, 2 4, 0 0.0824 0.676 0.903 0.044 1.09 0.325 5.22 2.18 391 0.996 0.002 8.84 5.04 99800 -3.6 4.37 0.41 0.388 0.0272 6.06e-06 7.23 3.8 121 0.975 0.011 44.6 0.159 5840000 PRS_PLINK_0.000251188643150958 218.2 Other benign neoplasm of uterus Female 10 17 2 neoplasms darkcyan 17, 10 4, 3 4, 4 4, 2 4, 1 0.332 0.612 0.587 0.231 1.39 0.512 5.02 0.239 1.45 0.869 0.061 1.27 0.0102 18.5 -0.738 4.34 0.865 0.063 0.478 4.49e-05 23800 -3.09 4.71 0.511 0.291 0.0455 4.15e-14 35 PRS_PLINK_0.000251188643150958 220 Benign neoplasm of ovary Female 1 8 2 neoplasms darkcyan 8, 1 2, 0 2, 0 2, 1 2, 0 1.11 3.5 0.751 0.124 3.04 2.8 3.27 0.482 11500 1 0 1.62 0.136 2.93 PRS_PLINK_0.000251188643150958 221 Benign neoplasm of other female genital organs Female 5 13 2 neoplasms darkcyan 13, 5 3, 3 3, 1 3, 0 3, 1 0.223 0.985 0.821 0.086 1.25 0.237 34.2 0.328 2.07 0.874 0.058 1.39 1 1.55 0.252 5.22 0.962 0.017 1.29 1.3 1.33 -2.61 5.26 0.619 0.208 0.0732 0.0599 35.3 PRS_PLINK_0.000251188643150958 222 Benign neoplasm of male genital organs Male 1 8 2 neoplasms darkcyan 8, 1 2, 1 2, 0 2, 0 2, 0 -0.592 23.1 0.98 0.009 0.553 0.216 1.37 0.307 370 0.999 0 1.36 0.496 3.28 -0.0682 2730 1 0 0.934 0.889 1.18 -0.0221 3600 1 0 0.978 0.267 1.84 PRS_PLINK_0.000251188643150958 223 Benign neoplasm of kidney and other urinary organs Both 2 7 2 neoplasms darkcyan 7, 2 2, 0 2, 1 1, 0 2, 1 -0.164 19.6 0.993 0.003 0.849 1.36 1.35 3.75 7130 1 0 42.5 1.23e-11 1.36e+09 -0.0684 219 1 0 0.934 0.763 1.39 PRS_PLINK_0.000251188643150958 224 Benign neoplasm of eye Both 2 8 2 neoplasms darkcyan 8, 2 2, 0 2, 1 2, 0 2, 1 0.307 10.2 0.976 0.011 1.36 1.54 2.68 -0.378 35400 1 0 0.685 0.00349 10.2 -0.231 26300 1 0 0.794 0.264 2.69 PRS_PLINK_0.000251188643150958 224.1 Benign neoplasm of eye, uveal Both 2 10 2 neoplasms darkcyan 10, 2 3, 0 2, 1 2, 0 3, 1 -0.118 2.13 0.956 0.02 0.889 0.0122 73.9 -0.0317 1820 1 0 0.969 0.316 3.39 -0.0483 3590 1 0 0.953 0.838 4.43 PRS_PLINK_0.000251188643150958 225 Benign neoplasm of brain and other parts of nervous system Both 0 13 2 neoplasms darkcyan 13, 0 4 3 3 3 PRS_PLINK_0.000251188643150958 225.1 Benign neoplasm of brain, cranial nerves, meninges Both 0 11 2 neoplasms darkcyan 11, 0 3 3 2 3 PRS_PLINK_0.000251188643150958 225.2 Benign neoplasm of spinal cord, meninges Both 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 226 Benign neoplasm of thyroid glands Both 0 14 2 neoplasms darkcyan 14, 0 4 3 3 4 PRS_PLINK_0.000251188643150958 227 Benign neoplasm of other endocrine glands and related structures Both 0 16 2 neoplasms darkcyan 16, 0 4 4 4 4 PRS_PLINK_0.000251188643150958 227.1 Benign neoplasm of adrenal gland Both 0 5 2 neoplasms darkcyan 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 227.2 Benign neoplasm of parathyroid gland Both 0 7 2 neoplasms darkcyan 7, 0 2 2 1 2 PRS_PLINK_0.000251188643150958 227.3 Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch) Both 0 4 2 neoplasms darkcyan 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 228 Hemangioma and lymphangioma, any site Both 1 28 2 neoplasms darkcyan 28, 1 7, 0 7, 0 7, 1 7, 0 -0.0536 0.805 0.947 0.024 0.948 0.0511 13.6 0.234 3.93 0.953 0.021 1.26 6.15e-06 89300 PRS_PLINK_0.000251188643150958 228.1 Hemangioma of skin and subcutaneous tissue Both 1 16 2 neoplasms darkcyan 16, 1 4, 0 4, 0 4, 1 4, 0 -0.322 1.1 0.769 0.114 0.725 0.0219 5.26 -0.21 2410 1 0 0.81 0.168 1.51 PRS_PLINK_0.000251188643150958 229 Benign neoplasm of unspecified sites Both 4 45 2 neoplasms darkcyan 45, 4 11, 1 11, 2 11, 1 11, 0 -0.598 0.692 0.388 0.411 0.55 0.0125 2.62 1.19 1.41 0.398 0.4 3.29 0.174 434 0.24 1.47 0.87 0.06 1.27 0.0305 91.7 -0.723 1.52 0.634 0.198 0.485 0.021 7.69 PRS_PLINK_0.000251188643150958 229.1 Benign neoplasm of lymph nodes Both 1 30 2 neoplasms darkcyan 30, 1 7, 0 7, 1 7, 0 8, 0 -0.178 0.804 0.824 0.084 0.837 0.0959 70.7 0.552 1.77 0.755 0.122 1.74 0.0783 154 PRS_PLINK_0.000251188643150958 240 Simple and unspecified goiter Both 2 15 3 endocrine/metabolic brown 15, 2 4, 0 4, 0 3, 0 4, 2 0.789 1.16 0.498 0.303 2.2 0.0923 34.8 0.302 141 0.998 0.001 1.35 1.4 9620000 PRS_PLINK_0.000251188643150958 241 Nontoxic nodular goiter Both 1 31 3 endocrine/metabolic brown 31, 1 7, 0 8, 0 7, 0 8, 1 0.616 0.725 0.395 0.403 1.85 0.484 19.4 0.47 2.68 0.861 0.065 1.6 0.00134 1550 PRS_PLINK_0.000251188643150958 241.1 Nontoxic uninodular goiter Both 0 30 3 endocrine/metabolic brown 30, 0 7 7 7 8 PRS_PLINK_0.000251188643150958 241.2 Nontoxic multinodular goiter Both 0 16 3 endocrine/metabolic brown 16, 0 4 4 4 4 PRS_PLINK_0.000251188643150958 242 Thyrotoxicosis with or without goiter Both 2 20 3 endocrine/metabolic brown 20, 2 5, 0 5, 0 5, 0 5, 2 0.166 1.42 0.907 0.043 1.18 0.0171 141 -0.467 4.08 0.909 0.041 0.627 0.000141 16000 PRS_PLINK_0.000251188643150958 242.1 Graves' disease Both 1 9 3 endocrine/metabolic brown 9, 1 3, 0 2, 0 2, 1 2, 0 -0.102 1040 1 0 0.903 0.434 1.74 -0.0277 2360 1 0 0.973 0.404 1.6 PRS_PLINK_0.000251188643150958 242.2 Toxic multinodular goiter Both 0 2 3 endocrine/metabolic brown 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 242.3 Exophthalmos Both 2 5 3 endocrine/metabolic brown 5, 2 2, 0 1, 0 1, 0 1, 2 0.0144 1080 1 0 1.01 0.771 1.37 0.125 17500 1 0 1.13 2.07e-08 3860 PRS_PLINK_0.000251188643150958 242.31 Thyrotoxic exophthalmos Both 1 2 3 endocrine/metabolic brown 2, 1 1, 0 0, 1 1, 0 1, 0 -0.424 25400 1 0 0.655 0.00254 5.22 -0.000695 175 1 0 0.999 0.957 1.02 PRS_PLINK_0.000251188643150958 244 Hypothyroidism Both 11 44 3 endocrine/metabolic brown 44, 11 10, 2 11, 0 11, 3 11, 6 0.799 0.536 0.136 0.867 2.22 0.889 7.57 -0.885 1.4 0.527 0.278 0.413 0.000925 6.83 1.13 1.32 0.391 0.407 3.09 0.328 58.7 0.5 1.39 0.719 0.144 1.65 0.149 25.8 PRS_PLINK_0.000251188643150958 244.1 Secondary hypothyroidism Both 2 28 3 endocrine/metabolic brown 28, 2 7, 0 7, 0 7, 0 7, 2 0.644 1.26 0.61 0.215 1.9 0.033 185 -1.23 3.09 0.691 0.161 0.293 8.67e-05 983 PRS_PLINK_0.000251188643150958 244.2 Acquired hypothyroidism Both 5 21 3 endocrine/metabolic brown 21, 5 6, 1 5, 0 5, 2 5, 2 0.708 0.652 0.278 0.556 2.03 0.69 8.85 0.353 3.22 0.913 0.04 1.42 0.00762 10800 0.551 2.14 0.797 0.098 1.73 0.064 23600 0.383 2.14 0.858 0.067 1.47 0.00399 112 PRS_PLINK_0.000251188643150958 244.4 Hypothyroidism NOS Both 10 44 3 endocrine/metabolic brown 44, 10 10, 2 11, 0 11, 2 11, 6 0.8 0.55 0.146 0.836 2.23 0.868 7.9 -0.885 1.4 0.527 0.278 0.413 0.000925 6.83 1.13 1.45 0.437 0.36 3.09 0.24 284 0.5 1.39 0.719 0.144 1.65 0.149 25.8 PRS_PLINK_0.000251188643150958 245 Thyroiditis Both 1 16 3 endocrine/metabolic brown 16, 1 4, 0 4, 0 4, 0 4, 1 0.693 0.831 0.404 0.394 2 0.489 22.8 0.656 245000 1 0 1.93 1.89 2.52 PRS_PLINK_0.000251188643150958 245.2 Chronic thyroiditis Both 1 14 3 endocrine/metabolic brown 14, 1 4, 0 3, 0 3, 0 4, 1 0.703 0.868 0.418 0.379 2.02 0.52 22.1 0.751 10 0.94 0.027 2.12 2.01 18.3 PRS_PLINK_0.000251188643150958 245.21 Chronic lymphocytic thyroiditis Both 1 13 3 endocrine/metabolic brown 13, 1 4, 0 3, 0 3, 0 3, 1 0.701 0.861 0.416 0.381 2.02 0.529 21.6 0.636 741 0.999 0 1.89 0.968 2.96 PRS_PLINK_0.000251188643150958 246 Other disorders of thyroid Both 8 40 3 endocrine/metabolic brown 40, 8 9, 2 10, 0 10, 2 10, 4 0.113 0.674 0.866 0.062 1.12 0.232 5.13 -0.701 1.65 0.672 0.173 0.496 7.35e-05 11.8 1.35 1.52 0.375 0.426 3.86 0.283 1410 -1.23 2.11 0.559 0.253 0.291 5.48e-05 24.5 PRS_PLINK_0.000251188643150958 246.2 Thyroid cyst Both 0 2 3 endocrine/metabolic brown 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 246.7 Abnormal results of function study of thyroid Both 1 16 3 endocrine/metabolic brown 16, 1 4, 0 4, 0 4, 0 4, 1 0.737 0.92 0.423 0.374 2.09 0.486 20 0.45 1780000 1 0 1.57 0.373 3.71 PRS_PLINK_0.000251188643150958 249 Secondary diabetes mellitus Both 7 5 3 endocrine/metabolic brown 5, 7 2, 3 1, 1 1, 2 1, 1 0.94 1.84 0.609 0.215 2.56 0.145 317 -0.0759 11300000 1 0 0.927 0.00668 76.2 -0.492 654 0.999 0 0.611 0.233 1.12 0.461 3070 1 0 1.59 0.191 1.73 PRS_PLINK_0.000251188643150958 250 Diabetes mellitus Both 32 29 3 endocrine/metabolic brown 29, 32 7, 7 7, 11 7, 6 7, 8 1.04 0.514 0.0439 1.358 2.82 1.2 10.1 0.146 1.19 0.903 0.044 1.16 0.0836 27.7 2.03 1.82 0.266 0.576 7.6 0.224 1130 1.41 1.22 0.249 0.603 4.09 0.564 45.3 PRS_PLINK_0.000251188643150958 250.1 Type 1 diabetes Both 29 8 3 endocrine/metabolic brown 8, 29 2, 7 2, 9 2, 1 2, 12 0.517 0.673 0.442 0.355 1.68 0.471 6.7 -0.381 1.49 0.798 0.098 0.683 0.00153 61.7 0.183 7.11 0.98 0.009 1.2 3.39e-09 915000 0.159 1.6 0.921 0.036 1.17 0.00319 49 PRS_PLINK_0.000251188643150958 250.11 Type 1 diabetes with ketoacidosis Both 6 1 3 endocrine/metabolic brown 1, 6 -0.0416 2710000 1 0 0.959 0.359 1.99 PRS_PLINK_0.000251188643150958 250.12 Type 1 diabetes with renal manifestations Both 17 3 3 endocrine/metabolic brown 3, 17 1, 4 1, 1 0, 7 1, 5 0.876 1.15 0.448 0.349 2.4 0.098 26 -0.118 2240 1 0 0.888 0.868 2.34 -0.0206 2.36 0.993 0.003 0.98 0.0203 618 2.61 6.4 0.684 0.165 13.6 0.00886 42500 PRS_PLINK_0.000251188643150958 250.13 Type 1 diabetes with ophthalmic manifestations Both 21 4 3 endocrine/metabolic brown 4, 21 1, 6 1, 2 1, 5 1, 8 0.393 0.888 0.658 0.182 1.48 0.0948 27.6 0.318 7.3 0.965 0.015 1.37 1.21 1.47 -0.0508 2.82 0.986 0.006 0.95 0.00125 262 0.384 1.82 0.833 0.079 1.47 0.0579 729 PRS_PLINK_0.000251188643150958 250.14 Type 1 diabetes with neurological manifestations Both 22 4 3 endocrine/metabolic brown 4, 22 1, 6 1, 6 1, 1 1, 9 0.85 1.26 0.499 0.302 2.34 0.101 171 -0.444 2.5 0.859 0.066 0.642 0.00348 161 -1.5e-12 50.8 1 0 1 7.06e-05 13400 -0.0801 1.89 0.966 0.015 0.923 0.000195 22.9 PRS_PLINK_0.000251188643150958 250.15 Diabetes type 1 with peripheral circulatory disorders Both 4 1 3 endocrine/metabolic brown 1, 4 -0.293 2960 1 0 0.746 0.401 1.66 PRS_PLINK_0.000251188643150958 250.2 Type 2 diabetes Both 30 26 3 endocrine/metabolic brown 26, 30 6, 7 6, 11 6, 4 7, 8 0.902 0.524 0.0853 1.069 2.46 0.994 8.6 0.393 1.23 0.749 0.125 1.48 0.105 53.8 0.355 1.4 0.8 0.097 1.43 0.068 78.4 0.956 2.26 0.672 0.172 2.6 0.000149 1160 PRS_PLINK_0.000251188643150958 250.21 Type 2 diabetes with ketoacidosis Both 6 0 3 endocrine/metabolic brown 0, 6 PRS_PLINK_0.000251188643150958 250.22 Type 2 diabetes with renal manifestations Both 4 6 3 endocrine/metabolic brown 6, 4 2, 2 1, 1 1, 1 2, 0 8.87e-14 14 1 0 1 1.49e-05 76600 0.167 987 1 0 1.18 0.664 3.86 0.474 3400 1 0 1.61 0.184 2070 0.212 1660 1 0 1.24 0.0502 23.9 PRS_PLINK_0.000251188643150958 250.23 Type 2 diabetes with ophthalmic manifestations Both 19 7 3 endocrine/metabolic brown 7, 19 2, 6 2, 8 1, 0 2, 5 0.418 0.844 0.62 0.207 1.52 0.129 20.5 0.121 1.51 0.936 0.029 1.13 0.0126 18.4 -0.0406 86.5 1 0 0.96 3.71e-07 3430000 0.617 2.23 0.782 0.107 1.85 0.0593 110 PRS_PLINK_0.000251188643150958 250.24 Type 2 diabetes with neurological manifestations Both 18 10 3 endocrine/metabolic brown 10, 18 3, 3 2, 3 2, 3 3, 9 0.111 0.961 0.908 0.042 1.12 0.0783 19.7 -0.393 3.04 0.897 0.047 0.675 0.00118 1560 -0.128 3.64 0.972 0.012 0.88 0.00706 467 0.201 2.16 0.926 0.033 1.22 0.0137 1240 PRS_PLINK_0.000251188643150958 250.25 Diabetes type 2 with peripheral circulatory disorders Both 2 3 3 endocrine/metabolic brown 3, 2 1, 2 1, 0 1, 0 1, 2 -0.045 4570 1 0 0.956 0.191 4.29 -0.0078 955 1 0 0.992 0.71 1.34 -0.0773 8120 1 0 0.926 0.0642 23.6 PRS_PLINK_0.000251188643150958 250.3 Insulin pump user Both 21 13 3 endocrine/metabolic brown 13, 21 4, 6 3, 3 3, 6 3, 6 0.621 0.54 0.25 0.601 1.86 0.738 5.68 -0.526 1.63 0.746 0.127 0.591 0.0411 29.2 1.22 1.79 0.495 0.305 3.39 0.178 55800 0.49 1.92 0.799 0.098 1.63 0.00219 378 PRS_PLINK_0.000251188643150958 250.4 Abnormal glucose Both 29 27 3 endocrine/metabolic brown 27, 29 6, 7 7, 11 6, 4 7, 7 0.566 0.646 0.38 0.42 1.76 0.477 8.36 0.105 1.2 0.93 0.031 1.11 0.0822 25.9 1.25 1.77 0.48 0.319 3.49 0.11 73800 -0.613 1.59 0.7 0.155 0.542 0.000156 52.7 PRS_PLINK_0.000251188643150958 250.41 Impaired fasting glucose Both 8 15 3 endocrine/metabolic brown 15, 8 4, 1 4, 4 3, 1 4, 2 0.665 0.744 0.371 0.43 1.94 0.37 10.9 0.0848 2.45 0.972 0.012 1.09 0.00473 110 1.22 9910000 1 0 3.38 0.247 90.7 2.18 4.38 0.618 0.209 8.84 0.012 7990 PRS_PLINK_0.000251188643150958 250.42 Other abnormal glucose Both 29 27 3 endocrine/metabolic brown 27, 29 6, 7 7, 11 6, 4 7, 7 0.566 0.646 0.38 0.42 1.76 0.477 8.36 0.105 1.2 0.93 0.031 1.11 0.0822 25.9 1.25 1.77 0.48 0.319 3.49 0.11 73800 -0.613 1.59 0.7 0.155 0.542 0.000156 52.7 PRS_PLINK_0.000251188643150958 250.6 Polyneuropathy in diabetes Both 22 7 3 endocrine/metabolic brown 7, 22 2, 3 2, 3 1, 3 2, 13 0.532 0.978 0.586 0.232 1.7 0.104 29.7 -2.32e-12 4.45 1 0 1 0.272 3.9 -1.1 71.6 0.988 0.005 0.331 0.213 779000 0.593 1.74 0.734 0.134 1.81 0.0116 157 PRS_PLINK_0.000251188643150958 250.7 Diabetic retinopathy Both 21 10 3 endocrine/metabolic brown 10, 21 3, 5 2, 8 2, 2 3, 6 0.132 0.576 0.818 0.087 1.14 0.413 3.37 0.343 1.54 0.824 0.084 1.41 0.0466 111 -0.102 2.83 0.971 0.013 0.903 0.0137 457 -0.277 1.2 0.817 0.088 0.758 0.0891 5.6 PRS_PLINK_0.000251188643150958 251 Other disorders of pancreatic internal secretion Both 10 16 3 endocrine/metabolic brown 16, 10 4, 1 4, 1 4, 2 4, 6 0.434 0.738 0.557 0.254 1.54 0.439 9.37 -0.117 1420 1 0 0.89 0.396 1.3 -0.121 1080 1 0 0.886 0.872 1.4 0.253 2.11 0.905 0.044 1.29 0.0219 767 PRS_PLINK_0.000251188643150958 251.1 Hypoglycemia Both 11 5 3 endocrine/metabolic brown 5, 11 2, 4 1, 3 1, 1 1, 3 -0.0482 0.917 0.958 0.019 0.953 0.0796 10 -0.782 23.4 0.973 0.012 0.457 0.513 152 -0.0583 1820 1 0 0.943 0.0843 1.38 -3.04 9.53 0.75 0.125 0.0481 0.0362 0.068 PRS_PLINK_0.000251188643150958 252 Disorders of parathyroid gland Both 2 21 3 endocrine/metabolic brown 21, 2 6, 0 5, 1 5, 0 5, 1 0.375 0.99 0.705 0.152 1.46 0.078 21.2 1.11 2.7 0.682 0.166 3.02 0.0211 348 0.207 6.37 0.974 0.011 1.23 0.00338 425 PRS_PLINK_0.000251188643150958 252.1 Hyperparathyroidism Both 2 21 3 endocrine/metabolic brown 21, 2 6, 0 5, 1 5, 0 5, 1 0.375 0.99 0.705 0.152 1.46 0.078 21.2 1.11 2.7 0.682 0.166 3.02 0.0211 348 0.207 6.37 0.974 0.011 1.23 0.00338 425 PRS_PLINK_0.000251188643150958 252.2 Hypoparathyroidism Both 0 5 3 endocrine/metabolic brown 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 253 Disorders of the pituitary gland and its hypothalamic control Both 2 14 3 endocrine/metabolic brown 14, 2 4, 1 3, 0 3, 0 4, 1 -0.49 1.11 0.66 0.18 0.613 0.0229 4.35 -0.00186 386 1 0 0.998 0.721 1.22 -2e-11 162 1 0 1 0.775 11900000 -0.0178 1930 1 0 0.982 0.846 1.98 PRS_PLINK_0.000251188643150958 253.1 Pituitary hyperfunction Both 0 6 3 endocrine/metabolic brown 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 253.11 Acromegaly and gigantism Both 0 1 3 endocrine/metabolic brown 1, 0 PRS_PLINK_0.000251188643150958 253.2 Pituitary hypofunction Both 1 7 3 endocrine/metabolic brown 7, 1 2, 0 2, 0 1, 0 2, 1 0.0528 479 1 0 1.05 0.858 1.13 0.362 6200 1 0 1.44 0.292 1.99 PRS_PLINK_0.000251188643150958 253.3 Diabetes insipidus Both 0 3 3 endocrine/metabolic brown 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 253.4 Anterior pituitary disorders Both 0 4 3 endocrine/metabolic brown 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 253.7 Other disorders of neurohypophysis Both 0 2 3 endocrine/metabolic brown 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 255 Disorders of adrenal glands Both 0 20 3 endocrine/metabolic brown 20, 0 5 5 5 5 PRS_PLINK_0.000251188643150958 255.1 Adrenal hyperfunction Both 0 3 3 endocrine/metabolic brown 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 255.11 Cushing's syndrome Both 0 1 3 endocrine/metabolic brown 1, 0 PRS_PLINK_0.000251188643150958 255.12 Hyperaldosteronism Both 0 1 3 endocrine/metabolic brown 1, 0 PRS_PLINK_0.000251188643150958 255.2 Adrenal hypofunction Both 0 7 3 endocrine/metabolic brown 7, 0 2 2 1 2 PRS_PLINK_0.000251188643150958 255.21 Glucocorticoid deficiency Both 0 7 3 endocrine/metabolic brown 7, 0 2 2 1 2 PRS_PLINK_0.000251188643150958 256 Ovarian dysfunction Female 2 11 3 endocrine/metabolic brown 11, 2 2, 0 3, 0 2, 2 3, 0 0.502 0.922 0.586 0.232 1.65 0.438 10.8 -0.0144 320 1 0 0.986 0.71 1.46 PRS_PLINK_0.000251188643150958 256.4 Polycystic ovaries Female 1 6 3 endocrine/metabolic brown 6, 1 1, 0 1, 0 1, 0 2, 1 1.27 1100000 1 0 3.57 1.95 8.56 2.37 4790 1 0 10.7 0.000135 1310 PRS_PLINK_0.000251188643150958 257 Testicular dysfunction Male 5 10 3 endocrine/metabolic brown 10, 5 3, 0 2, 1 2, 0 3, 4 1.6 1.36 0.237 0.625 4.97 0.46 91.7 0.133 1410 1 0 1.14 1.04 1.77 0.0295 278 1 0 1.03 0.194 2.72 PRS_PLINK_0.000251188643150958 257.1 Testicular hypofunction Male 5 11 3 endocrine/metabolic brown 11, 5 3, 0 3, 1 2, 0 3, 4 1.43 1.25 0.253 0.597 4.2 0.506 81.7 -0.267 13000 1 0 0.766 0.727 0.794 0.0295 278 1 0 1.03 0.194 2.72 PRS_PLINK_0.000251188643150958 258 Iatrogenic endocrine disorders Both 0 1 3 endocrine/metabolic brown 1, 0 PRS_PLINK_0.000251188643150958 259 Other endocrine disorders Both 2 15 3 endocrine/metabolic brown 15, 2 4, 0 4, 0 3, 1 4, 1 0.727 1.01 0.471 0.327 2.07 0.427 207 0.21 11000 1 0 1.23 0.353 16.9 -0.219 4560 1 0 0.803 0.273 2.22 PRS_PLINK_0.000251188643150958 260 Protein-calorie malnutrition Both 2 22 3 endocrine/metabolic brown 22, 2 6, 1 5, 0 5, 0 6, 1 -0.729 0.959 0.447 0.35 0.482 0.0119 4.99 -0.132 2.57 0.959 0.018 0.876 0.0127 48.6 -0.958 2.18 0.661 0.18 0.384 0.0104 15.5 -1.43 2.91 0.623 0.205 0.239 0.000192 13.8 PRS_PLINK_0.000251188643150958 260.2 severe protein-calorie malnutrition Both 1 12 3 endocrine/metabolic brown 12, 1 3, 1 3, 0 3, 0 3, 0 -0.444 0.816 0.587 0.232 0.642 0.131 2.49 -0.147 114 0.999 0 0.863 0.167 6.85 0.0862 306 1 0 1.09 0.833 1.21 0.25 7090000 1 0 1.28 0.329 5.41 PRS_PLINK_0.000251188643150958 260.22 Nutritional marasmus Both 1 4 3 endocrine/metabolic brown 4, 1 1, 1 1, 0 1, 0 1, 0 -0.0455 771 1 0 0.955 0.46 1.95 -0.00104 52 1 0 0.999 0.989 1.01 0.00166 260 1 0 1 0.976 1.03 0.0212 83.2 1 0 1.02 0.975 1.03 PRS_PLINK_0.000251188643150958 260.3 Adult failure to thrive Both 1 3 3 endocrine/metabolic brown 3, 1 1, 1 1, 0 1, 0 1, 1 0.00182 1370 1 0 1 0.874 1.33 1.71 7120 1 0 5.51 0.883 5.62 -0.0922 4480 1 0 0.912 0.302 1.62 PRS_PLINK_0.000251188643150958 260.6 Anorexia Both 1 4 3 endocrine/metabolic brown 4, 1 1, 0 1, 0 1, 1 1, 0 -6.84 2700 0.998 0.001 0.00107 1.28e-21 2.68e+14 -3.39 9810 1 0 0.0337 4.51e-10 184000 PRS_PLINK_0.000251188643150958 260.7 Polyphagia Both 0 2 3 endocrine/metabolic brown 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 261 Vitamin deficiency Both 20 37 3 endocrine/metabolic brown 37, 20 9, 5 9, 5 9, 4 9, 6 0.273 0.317 0.389 0.411 1.31 0.744 2.39 0.507 0.999 0.612 0.213 1.66 0.303 11 0.0858 1.3 0.948 0.023 1.09 0.0258 25.7 0.822 1.02 0.422 0.375 2.28 0.407 20.1 PRS_PLINK_0.000251188643150958 261.1 Vitamin A deficiency Both 2 0 3 endocrine/metabolic brown 0, 2 PRS_PLINK_0.000251188643150958 261.2 Vitamin B-complex deficiencies Both 1 7 3 endocrine/metabolic brown 7, 1 2, 0 2, 0 1, 1 2, 0 0.241 31 0.994 0.003 1.27 0.00729 224 0.00913 3020 1 0 1.01 0.679 1.42 PRS_PLINK_0.000251188643150958 261.4 Vitamin D deficiency Both 20 36 3 endocrine/metabolic brown 36, 20 8, 5 9, 5 9, 3 9, 7 0.273 0.317 0.39 0.409 1.31 0.745 2.39 0.297 1.1 0.787 0.104 1.35 0.195 9.92 -0.34 1.35 0.802 0.096 0.712 0.0417 15.4 1.11 1.17 0.343 0.465 3.03 0.42 46 PRS_PLINK_0.000251188643150958 262 Mineral deficiency NEC Both 7 13 3 endocrine/metabolic brown 13, 7 4, 0 3, 4 3, 1 3, 2 0.705 1.19 0.552 0.258 2.02 0.243 17.4 3.08 5.46 0.573 0.242 21.7 0.0161 6e+05 -0.0313 150 1 0 0.969 0.269 1.65 0.677 13200000 1 0 1.97 0.0896 20.4 PRS_PLINK_0.000251188643150958 263 Other nutritional deficiency Both 4 19 3 endocrine/metabolic brown 19, 4 5, 2 5, 1 4, 0 5, 1 -1.94 1.44 0.176 0.755 0.143 0.000445 5.7 0.225 2.12 0.915 0.038 1.25 0.00528 42.3 -2.17 12.7 0.865 0.063 0.115 1.12e-07 89400 -1.06 4.97 0.831 0.08 0.346 0.000141 760 PRS_PLINK_0.000251188643150958 264 Lack of normal physiological development Both 1 2 3 endocrine/metabolic brown 2, 1 1, 1 1, 0 1, 1 1, 0 -0.0551 8220 1 0 0.946 0.538 4.88e+08 0.00255 405 1 0 1 0.892 1.06 PRS_PLINK_0.000251188643150958 264.2 Failure to thrive (childhood) Both 1 4 3 endocrine/metabolic brown 4, 1 1, 1 1, 0 1, 0 1, 0 1.11 22300 1 0 3.05 0.0318 3.32 -0.0114 237 1 0 0.989 0.949 1.04 -0.0888 88.6 0.999 0 0.915 0.893 0.986 -0.00306 183 1 0 0.997 0.955 1.06 PRS_PLINK_0.000251188643150958 264.9 Lack of normal physiological development, unspecified Both 1 1 3 endocrine/metabolic brown 1, 1 -0.00285 64.9 1 0 0.997 0.958 1.04 PRS_PLINK_0.000251188643150958 269 Proteinuria Both 9 30 3 endocrine/metabolic brown 30, 9 8, 3 7, 3 7, 0 8, 3 -0.0914 0.466 0.844 0.073 0.913 0.37 2.01 0.678 1.58 0.668 0.176 1.97 0.0678 69 -0.855 2.08 0.681 0.167 0.425 0.000689 19.7 -0.795 1.7 0.64 0.194 0.452 0.00348 5.91 PRS_PLINK_0.000251188643150958 270 Disorders of protein plasma/amino-acid transport and metabolism Both 4 10 3 endocrine/metabolic brown 10, 4 3, 0 2, 1 2, 1 3, 2 0.473 4.08 0.908 0.042 1.6 7.39e-08 3260 -0.129 2110 1 0 0.879 0.726 2.06 0.519 5690 1 0 1.68 0.251 1.79 0.0204 1590 1 0 1.02 0.366 2.25 PRS_PLINK_0.000251188643150958 270.1 Disturbances of amino-acid transport Both 1 1 3 endocrine/metabolic brown 1, 1 -0.000334 33.8 1 0 1 0.995 1 PRS_PLINK_0.000251188643150958 270.11 Disturbances of sulphur-bearing amino-acid metabolism Both 1 0 3 endocrine/metabolic brown 0, 1 PRS_PLINK_0.000251188643150958 270.2 Disorders of amino-acid metabolism Both 0 4 3 endocrine/metabolic brown 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 270.3 Disorders of plasma protein metabolism Both 3 10 3 endocrine/metabolic brown 10, 3 3, 0 2, 2 2, 0 3, 1 -0.451 3.82 0.906 0.043 0.637 6.55e-06 9930 -0.145 3510 1 0 0.865 0.272 1.5 -0.103 2510 1 0 0.902 0.262 1.87 PRS_PLINK_0.000251188643150958 270.32 Paraproteinemia Both 2 6 3 endocrine/metabolic brown 6, 2 2, 0 1, 0 1, 0 2, 2 0.128 717 1 0 1.14 0.739 1.15 -0.00259 29.4 1 0 0.997 0.795 1.14 PRS_PLINK_0.000251188643150958 270.34 Alpha-1-antitrypsin deficiency Both 0 3 3 endocrine/metabolic brown 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 270.38 Other specified disorders of plasma protein metabolism Both 1 5 3 endocrine/metabolic brown 5, 1 2, 1 1, 0 1, 0 1, 0 0.165 1090 1 0 1.18 0.314 5.36 3.37e-05 6150 1 0 1 0.114 8.74 2.58e-05 1400 1 0 1 0.327 2.99 -0.102 2150 1 0 0.903 0.00274 3.94 PRS_PLINK_0.000251188643150958 271 Disorders of carbohydrate transport and metabolism Both 2 36 3 endocrine/metabolic brown 36, 2 9, 0 9, 0 9, 0 9, 2 0.54 0.542 0.319 0.497 1.72 0.656 7.76 1.04 1.46 0.474 0.324 2.84 0.244 179 PRS_PLINK_0.000251188643150958 271.3 Intestinal disaccharidase deficiencies and disaccharide malabsorption Both 1 33 3 endocrine/metabolic brown 33, 1 9, 0 8, 0 8, 0 8, 1 0.234 0.794 0.768 0.115 1.26 0.103 8.33 0.296 1.63 0.856 0.067 1.34 0.0424 47.7 PRS_PLINK_0.000251188643150958 271.9 Other disorders of carbohydrate transport and metabolism Both 1 3 3 endocrine/metabolic brown 3, 1 1, 0 1, 0 1, 1 1, 0 -1.02 5440 1 0 0.361 0.0907 2.88 0.0167 40.9 1 0 1.02 0.867 1.08 PRS_PLINK_0.000251188643150958 272 Disorders of lipoid metabolism Both 33 28 3 endocrine/metabolic brown 28, 33 6, 11 7, 10 7, 7 7, 5 -0.117 0.353 0.74 0.131 0.89 0.439 1.69 -0.15 0.875 0.864 0.064 0.86 0.17 4.03 -1.29 1.15 0.261 0.583 0.276 0.024 1.89 -0.64 1.1 0.56 0.251 0.527 0.0579 4.13 PRS_PLINK_0.000251188643150958 272.1 Hyperlipidemia Both 33 28 3 endocrine/metabolic brown 28, 33 6, 11 7, 10 7, 7 7, 5 -0.117 0.353 0.74 0.131 0.89 0.439 1.69 -0.15 0.875 0.864 0.064 0.86 0.17 4.03 -1.29 1.15 0.261 0.583 0.276 0.024 1.89 -0.64 1.1 0.56 0.251 0.527 0.0579 4.13 PRS_PLINK_0.000251188643150958 272.11 Hypercholesterolemia Both 16 19 3 endocrine/metabolic brown 19, 16 5, 5 5, 5 4, 4 5, 2 -0.371 0.519 0.475 0.324 0.69 0.262 1.68 0.311 1.54 0.84 0.076 1.37 0.107 19.5 -0.379 1.42 0.789 0.103 0.685 0.00996 6.24 -1.43 2.06 0.486 0.313 0.238 0.000377 5.86 PRS_PLINK_0.000251188643150958 272.12 Hyperglyceridemia Both 5 7 3 endocrine/metabolic brown 7, 5 2, 2 2, 0 1, 3 2, 0 0.418 1.62 0.796 0.099 1.52 0.0684 253 -0.00669 126 1 0 0.993 0.306 2.79 0.0439 69.4 0.999 0 1.04 0.543 2.55 0.05 2980 1 0 1.05 0.441 1.12 PRS_PLINK_0.000251188643150958 272.13 Mixed hyperlipidemia Both 14 17 3 endocrine/metabolic brown 17, 14 5, 3 4, 6 4, 3 4, 2 0.374 0.63 0.553 0.257 1.45 0.481 6.05 2.52 1.91 0.188 0.727 12.4 0.788 3080 0.842 1.7 0.62 0.208 2.32 0.174 3490 -0.00725 6.55 0.999 0 0.993 1.73e-06 67400 PRS_PLINK_0.000251188643150958 272.9 Unspecified disorder of lipoid metabolism Both 0 3 3 endocrine/metabolic brown 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 274 Gout and other crystal arthropathies Both 2 27 3 endocrine/metabolic brown 27, 2 7, 0 7, 0 6, 1 7, 1 0.488 0.773 0.528 0.278 1.63 0.075 88.7 0.276 3.26 0.932 0.03 1.32 0.00114 1870 1.17 4.96 0.813 0.09 3.23 0.000103 438000 PRS_PLINK_0.000251188643150958 274.1 Gout Both 2 27 3 endocrine/metabolic brown 27, 2 7, 0 7, 0 6, 1 7, 1 0.488 0.773 0.528 0.278 1.63 0.075 88.7 0.276 3.26 0.932 0.03 1.32 0.00114 1870 1.17 4.96 0.813 0.09 3.23 0.000103 438000 PRS_PLINK_0.000251188643150958 274.11 Gouty arthropathy Both 1 21 3 endocrine/metabolic brown 21, 1 6, 0 5, 0 5, 0 5, 1 0.11 0.956 0.909 0.042 1.12 0.0412 8.62 0.831 6.9 0.904 0.044 2.29 1.52e-05 74700000 PRS_PLINK_0.000251188643150958 274.2 Crystal arthropathies Both 0 2 3 endocrine/metabolic brown 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 274.21 Chondrocalcinosis Both 0 2 3 endocrine/metabolic brown 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 275 Disorders of mineral metabolism Both 7 47 3 endocrine/metabolic brown 47, 7 12, 2 12, 0 11, 2 12, 3 0.0315 0.46 0.945 0.024 1.03 0.441 2.82 -0.686 1.88 0.716 0.145 0.504 6.14e-05 67.8 0.359 1.24 0.771 0.113 1.43 0.125 20.2 -0.208 1.44 0.885 0.053 0.812 0.0311 55 PRS_PLINK_0.000251188643150958 275.1 Disorders of iron metabolism Both 0 4 4 hematopoietic darkorange1 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 275.11 Hereditary hemochromatosis Both 0 3 4 hematopoietic darkorange1 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 275.2 Disorders of copper metabolism Both 0 2 3 endocrine/metabolic brown 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 275.3 Disorders of magnesium metabolism Both 2 19 3 endocrine/metabolic brown 19, 2 5, 1 5, 0 4, 0 5, 1 0.138 1.1 0.901 0.045 1.15 0.0832 27 0.251 3.17 0.937 0.028 1.29 0.00554 819 8.1e-13 4.04 1 0 1 0.241 4.22 -0.945 3.5 0.787 0.104 0.389 0.000452 177 PRS_PLINK_0.000251188643150958 275.5 Disorders of calcium/phosphorus metabolism Both 4 40 3 endocrine/metabolic brown 40, 4 10, 1 10, 0 10, 2 10, 1 -0.242 0.752 0.748 0.126 0.785 0.118 4.64 -0.242 2.08 0.907 0.042 0.785 0.000367 600 2.52 2.09 0.228 0.642 12.4 0.37 164000 -0.576 1.71 0.736 0.133 0.562 0.00478 1490 PRS_PLINK_0.000251188643150958 275.51 Hypocalcemia Both 0 9 3 endocrine/metabolic brown 9, 0 3 2 2 2 PRS_PLINK_0.000251188643150958 275.53 Disorders of phosphorus metabolism Both 1 14 3 endocrine/metabolic brown 14, 1 4, 0 3, 0 3, 1 4, 0 0.128 0.894 0.886 0.053 1.14 0.204 10.8 1.31 24.1 0.957 0.019 3.7 3.59 28.6 PRS_PLINK_0.000251188643150958 275.6 Hypercalcemia Both 4 27 3 endocrine/metabolic brown 27, 4 7, 1 7, 0 6, 1 7, 2 -0.3 0.658 0.648 0.189 0.74 0.121 3.02 0.297 435 0.999 0 1.35 0.931 1.41 0.549 1.89 0.772 0.113 1.73 0.0169 178 -0.425 2.08 0.838 0.077 0.654 0.0055 52.9 PRS_PLINK_0.000251188643150958 276 Disorders of fluid, electrolyte, and acid-base balance Both 15 47 3 endocrine/metabolic brown 47, 15 11, 7 12, 6 11, 1 12, 1 -0.574 0.378 0.129 0.89 0.563 0.256 1.1 0.0555 0.827 0.946 0.024 1.06 0.237 4.63 -2.49 1.49 0.0944 1.025 0.083 0.000307 0.887 -2.07 1.28 0.105 0.977 0.126 0.0024 0.971 PRS_PLINK_0.000251188643150958 276.1 Electrolyte imbalance Both 11 40 3 endocrine/metabolic brown 40, 11 10, 6 10, 3 10, 0 10, 2 -0.736 0.488 0.131 0.882 0.479 0.154 1.09 -0.438 1.12 0.696 0.157 0.645 0.0729 4.27 -4.15 2.45 0.0902 1.045 0.0158 2.59e-07 0.908 -1.44 1.21 0.234 0.631 0.238 0.0088 1.61 PRS_PLINK_0.000251188643150958 276.11 Hyperosmolality and/or hypernatremia Both 0 7 3 endocrine/metabolic brown 7, 0 2 2 1 2 PRS_PLINK_0.000251188643150958 276.12 Hyposmolality and/or hyponatremia Both 4 25 3 endocrine/metabolic brown 25, 4 7, 3 6, 1 6, 0 6, 0 -0.753 0.885 0.395 0.403 0.471 0.0403 2.49 0.781 1.87 0.677 0.169 2.18 0.0571 109 -0.742 1.94 0.702 0.154 0.476 0.000166 10.6 -0.762 1.78 0.668 0.175 0.467 0.000753 8.2 PRS_PLINK_0.000251188643150958 276.13 Hyperpotassemia Both 3 27 3 endocrine/metabolic brown 27, 3 7, 0 7, 1 6, 0 7, 2 0.0636 0.685 0.926 0.033 1.07 0.181 4.44 0.34 2.04 0.868 0.062 1.4 0.0214 732 -0.119 1.93 0.951 0.022 0.888 0.000195 20.9 PRS_PLINK_0.000251188643150958 276.14 Hypopotassemia Both 2 29 3 endocrine/metabolic brown 29, 2 8, 2 7, 0 7, 0 7, 0 -0.175 0.719 0.808 0.093 0.839 0.106 3.92 -1.39 2.11 0.51 0.292 0.249 1.28e-07 5.48 0.032 1.76 0.986 0.006 1.03 0.0268 26.5 -0.796 1.65 0.63 0.201 0.451 0.00018 9.43 PRS_PLINK_0.000251188643150958 276.4 Acid-base balance disorder Both 2 22 3 endocrine/metabolic brown 22, 2 6, 1 5, 1 5, 0 6, 0 -0.0456 0.738 0.951 0.022 0.955 0.171 5.83 0.572 1.86 0.759 0.12 1.77 0.0992 2030 0.189 3.44 0.956 0.019 1.21 0.0012 13700 -0.522 2.12 0.806 0.094 0.593 0.00931 110 PRS_PLINK_0.000251188643150958 276.41 Acidosis Both 2 20 3 endocrine/metabolic brown 20, 2 5, 1 5, 1 5, 0 5, 0 -0.232 0.816 0.776 0.11 0.793 0.0915 4.76 -0.141 1.76 0.936 0.029 0.868 0.784 1.07 -0.714 3.01 0.812 0.09 0.49 0.00312 41.8 0.0781 2.28 0.973 0.012 1.08 0.0121 1430 PRS_PLINK_0.000251188643150958 276.42 Alkalosis Both 0 6 3 endocrine/metabolic brown 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 276.5 Hypovolemia Both 6 39 3 endocrine/metabolic brown 39, 6 10, 3 10, 3 9, 0 10, 0 -0.506 0.541 0.35 0.456 0.603 0.155 1.69 0.519 1.23 0.673 0.172 1.68 0.179 18.1 -0.326 1.64 0.843 0.074 0.722 0.000437 13.3 -0.884 1.39 0.526 0.279 0.413 0.0106 4.66 PRS_PLINK_0.000251188643150958 276.6 Fluid overload Both 0 16 3 endocrine/metabolic brown 16, 0 4 4 4 4 PRS_PLINK_0.000251188643150958 276.8 Polydipsia Both 0 3 3 endocrine/metabolic brown 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 277 Other disorders of metabolism Both 9 43 3 endocrine/metabolic brown 43, 9 10, 0 11, 4 10, 1 11, 4 0.451 0.459 0.326 0.487 1.57 0.657 3.9 3.06 1.91 0.11 0.959 21.3 1.02 5690000 0.744 1.66 0.654 0.185 2.1 0.0352 196 2.47 1.7 0.147 0.834 11.8 0.701 1.16e+08 PRS_PLINK_0.000251188643150958 277.2 Other disorders of purine and pyrimidine metabolism Both 0 18 3 endocrine/metabolic brown 18, 0 4 4 4 5 PRS_PLINK_0.000251188643150958 277.4 Disorders of bilirubin excretion Both 1 13 3 endocrine/metabolic brown 13, 1 4, 1 3, 0 3, 0 3, 0 0.826 1.52 0.588 0.231 2.29 0.195 42.6 0.0868 307 1 0 1.09 0.934 2.17 -1.08 11200000 1 0 0.34 0.00133 0.935 0.0676 5150 1 0 1.07 0.331 1.11 PRS_PLINK_0.000251188643150958 277.5 Other disorders of lipoid metabolism Both 2 21 3 endocrine/metabolic brown 21, 2 6, 1 5, 1 5, 0 5, 0 0.136 1.04 0.896 0.048 1.15 0.00305 50.2 0.112 2.1 0.958 0.019 1.12 0.027 64.8 0.241 2120 1 0 1.27 0.479 1.42 -0.379 4.19 0.928 0.032 0.684 0.00107 465 PRS_PLINK_0.000251188643150958 277.51 Lipoprotein disorders Both 0 16 3 endocrine/metabolic brown 16, 0 4 4 4 4 PRS_PLINK_0.000251188643150958 277.7 Dysmetabolic syndrome X Both 4 24 3 endocrine/metabolic brown 24, 4 6, 0 6, 1 6, 0 6, 3 0.153 0.791 0.847 0.072 1.16 0.0803 9.72 1.6 2.7 0.554 0.257 4.93 0.0672 3030 0.128 2.08 0.951 0.022 1.14 0.0065 51.3 PRS_PLINK_0.000251188643150958 278 Overweight, obesity and other hyperalimentation Both 22 42 3 endocrine/metabolic brown 42, 22 11, 2 10, 6 10, 5 11, 8 0.55 0.322 0.0873 1.059 1.73 0.987 3.35 2.01 1.35 0.138 0.859 7.44 0.865 324 1.26 1.28 0.325 0.489 3.53 0.377 207 1.45 1.04 0.162 0.79 4.28 0.743 32.1 PRS_PLINK_0.000251188643150958 278.1 Obesity Both 20 42 3 endocrine/metabolic brown 42, 20 11, 2 10, 6 10, 4 11, 7 0.509 0.321 0.112 0.95 1.66 0.945 3.18 2.01 1.35 0.138 0.859 7.44 0.865 324 1.26 1.25 0.311 0.507 3.54 0.381 86.7 1.41 1.06 0.184 0.735 4.08 0.694 31.2 PRS_PLINK_0.000251188643150958 278.11 Morbid obesity Both 6 38 3 endocrine/metabolic brown 38, 6 10, 1 9, 2 9, 1 10, 2 0.373 0.518 0.472 0.326 1.45 0.402 5.34 2.06 1.95 0.291 0.536 7.83 0.322 5310 1.25 1.59 0.433 0.364 3.48 0.221 21500 0.656 1.6 0.682 0.166 1.93 0.0133 44.5 PRS_PLINK_0.000251188643150958 278.3 Localized adiposity Both 0 8 3 endocrine/metabolic brown 8, 0 2 2 2 2 PRS_PLINK_0.000251188643150958 278.4 Abnormal weight gain Both 2 36 3 endocrine/metabolic brown 36, 2 9, 0 9, 0 9, 0 9, 2 1.05 0.863 0.223 0.652 2.86 0.59 332 1.96 1.82 0.282 0.55 7.08 0.352 2020 PRS_PLINK_0.000251188643150958 279 Disorders involving the immune mechanism Both 7 37 3 endocrine/metabolic brown 37, 7 9, 0 9, 3 9, 3 9, 1 0.338 0.456 0.459 0.338 1.4 0.598 3.66 1.56 2.31 0.5 0.301 4.74 0.0189 5270 -0.119 1.81 0.947 0.023 0.887 0.000331 127 0.816 1.62 0.614 0.212 2.26 0.0617 445 PRS_PLINK_0.000251188643150958 279.1 Immunity deficiency Both 3 15 3 endocrine/metabolic brown 15, 3 4, 0 4, 1 3, 1 4, 1 0.613 0.715 0.391 0.407 1.85 0.461 15.4 1.38e-11 51.6 1 0 1 0.00226 442 0.0146 75.1 1 0 1.01 0.751 1.43 -0.41 42.9 0.992 0.003 0.664 0.107 27 PRS_PLINK_0.000251188643150958 279.11 Deficiency of humoral immunity Both 2 6 3 endocrine/metabolic brown 6, 2 2, 0 1, 1 1, 0 2, 1 0.463 421000 1 0 1.59 1.05 2.5 2.75 32200 1 0 15.7 1.01e-10 1.47e+11 -0.347 27.3 0.99 0.004 0.707 0.12 2.65 PRS_PLINK_0.000251188643150958 279.2 Autoimmune disease NEC Both 3 12 3 endocrine/metabolic brown 12, 3 3, 1 3, 2 3, 0 3, 0 -0.343 2.4 0.887 0.052 0.71 2.48e-05 2090 1.35 124 0.991 0.004 3.86 0.606 16.4 0.034 883 1 0 1.03 0.767 1.67 -0.567 858 0.999 0 0.567 9.24e-05 7300 PRS_PLINK_0.000251188643150958 279.7 Other immunological findings Both 12 42 3 endocrine/metabolic brown 42, 12 10, 3 10, 5 10, 2 11, 2 -0.113 0.333 0.734 0.134 0.893 0.481 1.64 1.32 1.12 0.242 0.616 3.73 0.576 40.2 -0.773 1.56 0.62 0.208 0.462 0.00468 7.57 -0.947 1.28 0.46 0.337 0.388 0.0207 4.55 PRS_PLINK_0.000251188643150958 279.8 Other specified disorders involving the immune mechanism Both 3 9 3 endocrine/metabolic brown 9, 3 2, 0 2, 3 2, 0 2, 0 -0.0299 1.06 0.978 0.01 0.971 0.164 6.67 0.493 211 0.998 0.001 1.64 0.00136 2000 PRS_PLINK_0.000251188643150958 280 Iron deficiency anemias Both 11 40 4 hematopoietic darkorange1 40, 11 9, 2 10, 2 10, 2 10, 5 0.344 0.358 0.337 0.472 1.41 0.753 2.88 0.226 1.41 0.872 0.059 1.25 0.0621 265 -0.315 1.35 0.816 0.088 0.73 0.0237 10.2 0.819 1.12 0.464 0.334 2.27 0.343 19.3 PRS_PLINK_0.000251188643150958 280.1 Iron deficiency anemias, unspecified or not due to blood loss Both 11 39 4 hematopoietic darkorange1 39, 11 9, 2 10, 2 9, 2 10, 5 0.344 0.358 0.337 0.472 1.41 0.754 2.87 0.226 1.41 0.872 0.059 1.25 0.0621 265 -0.834 1.56 0.592 0.228 0.434 0.000277 9.85 0.887 1.12 0.429 0.367 2.43 0.366 20.1 PRS_PLINK_0.000251188643150958 280.2 Iron deficiency anemia secondary to blood loss (chronic) Both 3 16 4 hematopoietic darkorange1 16, 3 3, 1 4, 0 4, 0 4, 2 2.17 1.52 0.152 0.817 8.74 0.91 558 -0.12 45800 1 0 0.887 0.557 1.37 -4.19 50900000 1 0 0.0151 5.38e-08 16700 7.57 92.7 0.935 0.029 1950 3120 4450 PRS_PLINK_0.000251188643150958 281 Other deficiency anemia Both 1 6 4 hematopoietic darkorange1 6, 1 2, 1 1, 0 1, 0 2, 0 -1.86 179 0.992 0.004 0.155 5.26e-07 596000 -1 5400 1 0 0.368 0.31 2.72 0.137 4250 1 0 1.15 0.43 3.61 0.311 3000 1 0 1.36 0.216 8.71 PRS_PLINK_0.000251188643150958 281.1 Megaloblastic anemia Both 0 4 4 hematopoietic darkorange1 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 281.11 Pernicious anemia Both 0 3 4 hematopoietic darkorange1 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 281.12 Other vitamin B12 deficiency anemia Both 0 3 4 hematopoietic darkorange1 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 281.9 Deficiency anemias Both 1 1 4 hematopoietic darkorange1 1, 1 0.0047 26.3 1 0 1 0.935 1.08 PRS_PLINK_0.000251188643150958 282 Hereditary hemolytic anemias Both 1 5 4 hematopoietic darkorange1 5, 1 2, 0 1, 0 1, 0 1, 1 0.622 3080 1 0 1.86 0.17 19.2 -0.0211 25.2 0.999 0 0.979 0.842 1.27 PRS_PLINK_0.000251188643150958 282.8 Other hemoglobinopathies Both 1 3 4 hematopoietic darkorange1 3, 1 1, 0 1, 0 0, 1 1, 0 0.216 2170 1 0 1.24 0.694 1.44 -0.0146 68.1 1 0 0.986 0.457 2.91 PRS_PLINK_0.000251188643150958 282.9 Other hereditary hemolytic anemias Both 1 2 4 hematopoietic darkorange1 2, 1 1, 0 0, 1 1, 0 1, 0 -0.0432 1260 1 0 0.958 0.585 4.36 -0.0155 93.2 1 0 0.985 0.915 1.06 PRS_PLINK_0.000251188643150958 284 Aplastic anemia Both 1 7 4 hematopoietic darkorange1 7, 1 2, 1 2, 0 1, 0 2, 0 -0.143 69.9 0.998 0.001 0.866 0.976 3.71 0.0354 1190 1 0 1.04 0.745 1.08 -0.172 1890 1 0 0.842 0.765 1.41 -0.151 1100 1 0 0.86 0.499 1.3 PRS_PLINK_0.000251188643150958 284.1 Pancytopenia Both 1 6 4 hematopoietic darkorange1 6, 1 2, 1 1, 0 1, 0 2, 0 0.14 51 0.998 0.001 1.15 0.828 1.55 0.0144 4190 1 0 1.01 0.322 10.1 -0.172 1890 1 0 0.842 0.765 1.41 -0.151 1100 1 0 0.86 0.499 1.3 PRS_PLINK_0.000251188643150958 285 Other anemias Both 13 43 4 hematopoietic darkorange1 43, 13 10, 3 11, 1 10, 3 11, 6 0.375 0.404 0.353 0.452 1.46 0.69 3.28 -0.927 1.11 0.404 0.393 0.396 0.0318 2.88 -0.914 1.27 0.472 0.326 0.401 0.0196 4.29 0.831 0.972 0.393 0.406 2.3 0.448 13.4 PRS_PLINK_0.000251188643150958 285.1 Acute posthemorrhagic anemia Both 0 29 4 hematopoietic darkorange1 29, 0 7 7 7 7 PRS_PLINK_0.000251188643150958 285.2 Anemia of chronic disease Both 1 23 4 hematopoietic darkorange1 23, 1 6, 0 6, 0 5, 1 6, 0 0.666 1.04 0.524 0.281 1.95 0.146 85 0.03 604 1 0 1.03 0.774 1.49 PRS_PLINK_0.000251188643150958 285.21 Anemia in chronic kidney disease Both 0 16 4 hematopoietic darkorange1 16, 0 4 4 4 4 PRS_PLINK_0.000251188643150958 285.22 Anemia in neoplastic disease Both 0 5 4 hematopoietic darkorange1 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 286 Coagulation defects Both 7 40 4 hematopoietic darkorange1 40, 7 10, 4 10, 1 10, 2 10, 0 -0.528 0.572 0.356 0.448 0.59 0.131 1.71 -0.209 1.33 0.875 0.058 0.812 0.0459 15 0.426 1.28 0.74 0.131 1.53 0.142 19.4 -0.684 1.32 0.605 0.218 0.505 0.0328 35.1 PRS_PLINK_0.000251188643150958 286.1 Congenital coagulation defects Both 0 8 4 hematopoietic darkorange1 8, 0 2 2 2 2 PRS_PLINK_0.000251188643150958 286.11 Von willebrand's disease Both 0 3 4 hematopoietic darkorange1 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 286.12 Congenital deficiency of other clotting factors (including factor VII) Both 0 4 4 hematopoietic darkorange1 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 286.2 Encounter for long-term (current) use of anticoagulants Both 3 32 4 hematopoietic darkorange1 32, 3 8, 1 8, 0 8, 1 8, 1 0.889 0.878 0.311 0.507 2.43 0.352 168000 0.44 1.95 0.822 0.085 1.55 0.0014 536 1.22 1.7 0.475 0.323 3.37 0.115 4340 0.686 1.86 0.712 0.147 1.98 0.00678 26200 PRS_PLINK_0.000251188643150958 286.3 Coagulation defects complicating pregnancy or postpartum Female 1 2 4 hematopoietic darkorange1 2, 1 1, 1 1, 0 1, 1 1, 0 -14.7 19200 0.999 0 4.31e-07 2.33e-28 1e+11 -8.69 1.48e+09 1 0 0.000168 8.39e-29 1.81e+19 PRS_PLINK_0.000251188643150958 286.4 Acquired coagulation factor deficiency Both 0 3 4 hematopoietic darkorange1 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 286.5 Hemorrhagic disorder due to intrinsic circulating anticoagulants Both 0 4 4 hematopoietic darkorange1 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 286.6 Defibrination syndrome Both 5 37 4 hematopoietic darkorange1 37, 5 10, 2 9, 2 9, 1 9, 0 -0.27 0.517 0.602 0.221 0.763 0.197 2.55 0.749 1.25 0.549 0.26 2.12 0.229 257 0.577 2 0.772 0.112 1.78 0.000173 11400 -0.385 1.47 0.793 0.1 0.68 0.0319 12.7 PRS_PLINK_0.000251188643150958 286.7 Other and unspecified coagulation defects Both 6 40 4 hematopoietic darkorange1 40, 6 10, 3 10, 2 10, 1 10, 0 -0.448 0.532 0.4 0.398 0.639 0.155 1.68 0.283 1.22 0.816 0.089 1.33 0.124 12.8 0.127 1.91 0.947 0.024 1.14 0.00175 1080 -0.577 1.34 0.666 0.177 0.562 0.035 14.3 PRS_PLINK_0.000251188643150958 286.8 Hypercoagulable state Both 1 13 4 hematopoietic darkorange1 13, 1 4, 1 3, 0 3, 0 3, 0 0.0475 1.19 0.968 0.014 1.05 0.0799 11.3 2.02 976 0.998 0.001 7.52 0.0165 5140 0.17 585 1 0 1.19 0.324 1.76 -0.275 1760 1 0 0.759 0.0181 10.8 PRS_PLINK_0.000251188643150958 286.81 Primary hypercoagulable state Both 1 11 4 hematopoietic darkorange1 11, 1 3, 1 3, 0 2, 0 3, 0 0.125 1.86 0.946 0.024 1.13 0.0166 23.8 0.0101 84.6 1 0 1.01 0.855 1.25 -5.67 1190 0.996 0.002 0.00344 2.86e-15 6.67e+10 0.826 1920 1 0 2.28 0.000421 971 PRS_PLINK_0.000251188643150958 286.9 Abnormal coagulation profile Both 2 14 4 hematopoietic darkorange1 14, 2 4, 1 3, 1 3, 0 4, 0 0.134 1.13 0.905 0.043 1.14 0.179 73.4 0.389 3760 1 0 1.48 0.803 1.65 0.0585 5360 1 0 1.06 0.327 10.3 -0.0175 447 1 0 0.983 0.607 1.15 PRS_PLINK_0.000251188643150958 287 Purpura and other hemorrhagic conditions Both 3 36 4 hematopoietic darkorange1 36, 3 9, 2 9, 1 9, 0 9, 0 -1.03 0.867 0.234 0.631 0.356 0.0335 2.3 0.651 1.8 0.717 0.144 1.92 0.0556 8500 -0.463 1.37 0.735 0.134 0.63 0.0168 12.1 -0.21 1.63 0.898 0.047 0.811 0.0214 11.9 PRS_PLINK_0.000251188643150958 287.1 Spontaneous ecchymoses Both 0 3 4 hematopoietic darkorange1 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 287.3 Thrombocytopenia Both 3 33 4 hematopoietic darkorange1 33, 3 9, 2 8, 1 8, 0 8, 0 -1.48 1.02 0.148 0.829 0.228 1.18e-06 2.15 1.25 1.86 0.503 0.298 3.48 0.0606 19300 -0.475 1.38 0.731 0.136 0.622 0.0135 6.99 -0.117 1.58 0.941 0.027 0.889 0.0208 16.5 PRS_PLINK_0.000251188643150958 287.31 Primary thrombocytopenia Both 1 5 4 hematopoietic darkorange1 5, 1 2, 1 1, 0 1, 0 1, 0 0.55 6840 1 0 1.73 0.233 2.26 -0.0167 281 1 0 0.983 0.841 1.12 1.25 18200 1 0 3.49 0.236 4.25 1.01 4770 1 0 2.74 0.289 3.03 PRS_PLINK_0.000251188643150958 287.32 Secondary thrombocytopenia Both 1 10 4 hematopoietic darkorange1 10, 1 3, 1 2, 0 2, 0 3, 0 -0.767 1.58 0.627 0.203 0.464 0.441 3.55 0.762 2000 1 0 2.14 0.000403 76200 0.308 8350 1 0 1.36 0.0208 16.1 -0.0837 2850 1 0 0.92 0.167 5.3 PRS_PLINK_0.000251188643150958 287.4 Qualitative platelet defects Both 0 2 4 hematopoietic darkorange1 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 288 Diseases of white blood cells Both 7 51 4 hematopoietic darkorange1 51, 7 12, 2 13, 3 12, 2 13, 0 -0.486 0.475 0.307 0.513 0.615 0.203 1.56 0.308 1.16 0.79 0.102 1.36 0.15 13.3 0.274 1.4 0.845 0.073 1.31 0.0469 20.4 -0.655 1.27 0.607 0.217 0.519 0.0134 5.65 PRS_PLINK_0.000251188643150958 288.1 Decreased white blood cell count Both 2 19 4 hematopoietic darkorange1 19, 2 5, 0 5, 0 4, 2 5, 0 -0.247 1.09 0.821 0.086 0.782 0.016 22.1 0.755 5.52 0.891 0.05 2.13 0.0192 290 PRS_PLINK_0.000251188643150958 288.11 Neutropenia Both 2 17 4 hematopoietic darkorange1 17, 2 5, 0 4, 0 4, 2 4, 0 -0.193 1.22 0.874 0.058 0.824 0.019 21.4 -0.661 14.9 0.965 0.016 0.516 2.83e-06 95700 PRS_PLINK_0.000251188643150958 288.2 Elevated white blood cell count Both 5 47 4 hematopoietic darkorange1 47, 5 11, 1 12, 2 11, 1 12, 1 -0.298 0.514 0.561 0.251 0.742 0.197 2.05 1.03 1.46 0.483 0.316 2.79 0.165 153 0.314 1.47 0.83 0.081 1.37 0.0142 29.7 -0.712 1.57 0.651 0.186 0.491 0.000465 18.3 PRS_PLINK_0.000251188643150958 288.3 Eosinophilia Both 2 0 4 hematopoietic darkorange1 0, 2 PRS_PLINK_0.000251188643150958 289 Other diseases of blood and blood-forming organs Both 2 26 4 hematopoietic darkorange1 26, 2 7, 0 6, 2 6, 0 7, 0 -0.169 1.04 0.871 0.06 0.845 0.054 203 1.9 2.01 0.344 0.463 6.7 0.216 410 PRS_PLINK_0.000251188643150958 289.3 Personal history of diseases of blood and blood-forming organs Both 1 15 4 hematopoietic darkorange1 15, 1 4, 1 4, 0 3, 0 4, 0 -0.575 1.5 0.702 0.154 0.563 0.000954 5.08 0.363 896 1 0 1.44 1.35 1.55 -1.69 6470000 1 0 0.185 0.0119 1.6 0.0741 4830 1 0 1.08 0.327 2.33 PRS_PLINK_0.000251188643150958 289.4 Lymphadenitis Both 5 45 4 hematopoietic darkorange1 45, 5 11, 0 11, 4 11, 0 11, 1 0.0794 0.418 0.849 0.071 1.08 0.488 2.62 1.71 1.6 0.286 0.544 5.53 0.353 8790 0.304 1.42 0.83 0.081 1.36 0.0263 40.5 PRS_PLINK_0.000251188643150958 289.5 Diseases of spleen Both 0 5 4 hematopoietic darkorange1 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 289.8 Polycythemia, secondary Both 1 9 4 hematopoietic darkorange1 9, 1 3, 0 2, 0 2, 1 2, 0 -0.0584 2150000 1 0 0.943 0.239 2.16 -0.772 8830 1 0 0.462 0.168 3.8 PRS_PLINK_0.000251188643150958 289.9 Abnormality of red blood cells Both 0 8 4 hematopoietic darkorange1 8, 0 2 2 2 2 PRS_PLINK_0.000251188643150958 290 Delirium dementia and amnestic and other cognitive disorders Both 1 9 5 mental disorders magenta 9, 1 3, 0 2, 1 2, 0 2, 0 -0.668 7.31 0.927 0.033 0.513 0.483 0.547 0.0925 480 1 0 1.1 0.661 2.3 PRS_PLINK_0.000251188643150958 290.1 Dementias Both 1 2 5 mental disorders magenta 2, 1 1, 1 1, 0 1, 1 1, 0 0.244 12300 1 0 1.28 0.297 2.19 0.413 9860 1 0 1.51 0.362 3.08 PRS_PLINK_0.000251188643150958 290.11 Alzheimer's disease Both 0 1 5 mental disorders magenta 1, 0 PRS_PLINK_0.000251188643150958 290.13 Senile dementia Both 1 3 5 mental disorders magenta 3, 1 1, 1 1, 0 1, 0 1, 1 0.755 6650 1 0 2.13 0.0351 87.5 0.413 9860 1 0 1.51 0.362 3.08 -0.00196 14.3 1 0 0.998 0.901 1.06 PRS_PLINK_0.000251188643150958 290.2 Delirium due to conditions classified elsewhere Both 0 5 5 mental disorders magenta 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 290.3 Other persistent mental disorders due to conditions classified elsewhere Both 0 10 5 mental disorders magenta 10, 0 3 2 2 3 PRS_PLINK_0.000251188643150958 291 Other specified nonpsychotic and/or transient mental disorders Both 2 36 5 mental disorders magenta 36, 2 9, 1 9, 1 9, 0 9, 0 -0.253 0.593 0.669 0.175 0.776 0.0974 3.56 0.668 1.84 0.717 0.144 1.95 0.0607 302 -0.714 2.16 0.741 0.13 0.49 5.66e-05 228 -0.293 1.81 0.872 0.06 0.746 0.0276 175 PRS_PLINK_0.000251188643150958 291.1 Transient mental disorders due to conditions classified elsewhere Both 0 4 5 mental disorders magenta 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 291.4 Specific nonpsychotic mental disorders due to brain damage Both 0 9 5 mental disorders magenta 9, 0 3 2 2 2 PRS_PLINK_0.000251188643150958 291.8 Alteration of consciousness Both 2 27 5 mental disorders magenta 27, 2 7, 1 7, 1 6, 0 7, 0 0.121 0.721 0.867 0.062 1.13 0.273 56.7 0.834 2.16 0.699 0.156 2.3 0.0263 452 -0.656 2.55 0.797 0.099 0.519 0.404 3.02 -0.126 2.79 0.964 0.016 0.881 0.0101 84.4 PRS_PLINK_0.000251188643150958 292 Neurological disorders Both 8 51 5 mental disorders magenta 51, 8 13, 5 13, 1 12, 0 13, 2 -0.304 0.47 0.518 0.285 0.738 0.269 1.91 -2.16 1.45 0.137 0.863 0.115 0.000748 1.53 -3.29 1.89 0.0826 1.083 0.0373 1.08e-06 0.935 0.00973 1.18 0.993 0.003 1.01 0.0904 68.6 PRS_PLINK_0.000251188643150958 292.1 Aphasia/speech disturbance Both 3 20 5 mental disorders magenta 20, 3 5, 1 5, 1 5, 1 5, 0 -0.307 1.67 0.854 0.068 0.736 0.00419 73.3 0.35 9.02 0.969 0.014 1.42 1.27 1720 -0.556 3.38 0.869 0.061 0.574 0.000105 164 -0.62 2.98 0.835 0.078 0.538 0.000892 173 PRS_PLINK_0.000251188643150958 292.11 Aphasia Both 2 0 5 mental disorders magenta 0, 2 PRS_PLINK_0.000251188643150958 292.12 Symbolic dysfunction Both 1 4 5 mental disorders magenta 4, 1 1, 1 1, 0 1, 0 1, 0 0.182 375000 1 0 1.2 0.425 6.59 0.028 174 1 0 1.03 0.717 1.45 0.00874 41.3 1 0 1.01 0.917 1.15 0.00318 49.2 1 0 1 0.814 1.22 PRS_PLINK_0.000251188643150958 292.2 Mild cognitive impairment Both 1 3 5 mental disorders magenta 3, 1 1, 0 1, 0 1, 1 1, 0 -0.551 10800 1 0 0.576 0.398 5.27 -0.00745 32.8 1 0 0.993 0.894 1.07 PRS_PLINK_0.000251188643150958 292.3 Memory loss Both 2 24 5 mental disorders magenta 24, 2 6, 1 6, 1 6, 0 6, 0 -0.157 0.733 0.83 0.081 0.854 0.0471 4.13 2.33 2.96 0.431 0.365 10.3 0.114 362000 -0.836 2.32 0.719 0.143 0.433 0.00324 18.7 0.238 1.67 0.887 0.052 1.27 0.0825 24 PRS_PLINK_0.000251188643150958 292.4 Altered mental status Both 3 28 5 mental disorders magenta 28, 3 7, 2 7, 0 7, 1 7, 0 -0.152 0.676 0.822 0.085 0.859 0.171 3.54 -1.82 1.86 0.327 0.485 0.162 0.000162 2.88 -0.569 1.51 0.707 0.151 0.566 0.00942 6.99 -1.14 2.26 0.614 0.212 0.32 7.58e-05 10.2 PRS_PLINK_0.000251188643150958 292.5 Transient alteration of awareness Both 0 7 5 mental disorders magenta 7, 0 2 2 1 2 PRS_PLINK_0.000251188643150958 292.6 Hallucinations Both 0 2 5 mental disorders magenta 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 293 Symptoms involving head and neck Both 2 9 5 mental disorders magenta 9, 2 3, 0 2, 1 2, 1 2, 0 -0.233 3.01 0.938 0.028 0.792 0.761 0.851 0.27 1890 1 0 1.31 1.13 2.45 0.323 7790 1 0 1.38 0.197 85.6 PRS_PLINK_0.000251188643150958 293.1 Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS] Both 4 47 5 mental disorders magenta 47, 4 11, 0 12, 1 11, 2 12, 1 0.741 0.759 0.329 0.483 2.1 0.245 72.2 0.179 1.66 0.914 0.039 1.2 0.0053 96.3 0.413 1.58 0.794 0.1 1.51 0.00846 1080 0.423 1.35 0.753 0.123 1.53 0.0085 112 PRS_PLINK_0.000251188643150958 295 Schizophrenia and other psychotic disorders Both 0 7 5 mental disorders magenta 7, 0 2 2 1 2 PRS_PLINK_0.000251188643150958 295.1 Schizophrenia Both 0 1 5 mental disorders magenta 1, 0 PRS_PLINK_0.000251188643150958 295.2 Paranoid disorders Both 0 3 5 mental disorders magenta 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 295.3 Psychosis Both 0 7 5 mental disorders magenta 7, 0 2 2 1 2 PRS_PLINK_0.000251188643150958 296 Mood disorders Both 29 19 5 mental disorders magenta 19, 29 5, 9 5, 6 4, 7 5, 6 0.000174 0.361 1 0 1 0.495 1.9 -1.52 1.55 0.325 0.488 0.218 0.00639 2.68 1.5 1.35 0.266 0.575 4.5 0.477 153 -1.1 1.45 0.445 0.352 0.331 0.00433 3.67 PRS_PLINK_0.000251188643150958 296.1 Bipolar Both 2 13 5 mental disorders magenta 13, 2 4, 0 3, 0 3, 0 3, 2 0.809 1.1 0.464 0.334 2.25 0.275 14.1 0.0426 2710000 1 0 1.04 0.0761 35.1 PRS_PLINK_0.000251188643150958 296.2 Depression Both 28 19 5 mental disorders magenta 19, 28 5, 9 5, 5 4, 7 5, 6 0.000604 0.359 0.999 0.001 1 0.499 1.9 -1.81 1.65 0.274 0.562 0.164 0.00284 2.28 1.5 1.35 0.266 0.575 4.5 0.477 153 -1.1 1.45 0.445 0.352 0.331 0.00433 3.67 PRS_PLINK_0.000251188643150958 296.22 Major depressive disorder Both 28 19 5 mental disorders magenta 19, 28 5, 9 5, 5 4, 7 5, 6 0.000604 0.359 0.999 0.001 1 0.499 1.9 -1.81 1.65 0.274 0.562 0.164 0.00284 2.28 1.5 1.35 0.266 0.575 4.5 0.477 153 -1.1 1.45 0.445 0.352 0.331 0.00433 3.67 PRS_PLINK_0.000251188643150958 297 Suicidal ideation or attempt Both 1 14 5 mental disorders magenta 14, 1 4, 1 3, 0 3, 0 4, 0 -0.437 1.47 0.766 0.116 0.646 0.0166 7.66 -2.01 103 0.984 0.007 0.134 1.32e-05 1330 0.193 1950 1 0 1.21 0.771 3.13 -0.44 687 0.999 0 0.644 0.167 9.08 PRS_PLINK_0.000251188643150958 297.1 Suicidal ideation Both 1 10 5 mental disorders magenta 10, 1 3, 1 2, 0 2, 0 3, 0 -0.212 2.7 0.937 0.028 0.809 0.784 0.832 -0.101 279 1 0 0.904 0.629 1.2 0.0986 953 1 0 1.1 0.881 1.33 -0.263 222 0.999 0 0.768 0.284 0.668 PRS_PLINK_0.000251188643150958 297.2 Suicide or self-inflicted injury Both 0 7 5 mental disorders magenta 7, 0 2 2 1 2 PRS_PLINK_0.000251188643150958 300 Anxiety disorders Both 25 19 5 mental disorders magenta 19, 25 5, 9 5, 4 4, 7 5, 5 0.147 0.38 0.699 0.155 1.16 0.566 2.35 -2.7 1.94 0.165 0.784 0.0673 6.12e-05 1.27 0.36 1.03 0.727 0.139 1.43 0.263 10 -2.5 1.84 0.175 0.758 0.0818 1.43e-05 2.58 PRS_PLINK_0.000251188643150958 300.1 Anxiety disorder Both 24 19 5 mental disorders magenta 19, 24 5, 9 5, 3 4, 7 5, 5 0.143 0.378 0.705 0.152 1.15 0.567 2.34 -3.73 2.55 0.143 0.843 0.0241 1.39e-06 0.956 0.36 1.03 0.727 0.139 1.43 0.263 10 -2.5 1.84 0.175 0.758 0.0818 1.43e-05 2.58 PRS_PLINK_0.000251188643150958 300.11 Generalized anxiety disorder Both 12 18 5 mental disorders magenta 18, 12 5, 4 4, 1 4, 4 5, 3 0.4 0.583 0.492 0.308 1.49 0.58 5.7 -2.8 4.1 0.495 0.306 0.0607 5.29e-06 31.3 0.0913 2.56 0.971 0.013 1.1 0.00507 94.8 -0.768 2.37 0.746 0.127 0.464 0.00401 51.6 PRS_PLINK_0.000251188643150958 300.12 Agorophobia, social phobia, and panic disorder Both 2 15 5 mental disorders magenta 15, 2 4, 2 4, 0 3, 0 4, 0 -1.66 1.73 0.338 0.472 0.19 9.98e-06 15.7 -3.38 5.26 0.521 0.284 0.0341 1.45e-06 48.1 -2.78 120 0.981 0.008 0.0621 4.19e-05 65.8 -3.53 7.1 0.619 0.208 0.0292 0.0248 95.3 PRS_PLINK_0.000251188643150958 300.13 Phobia Both 3 12 5 mental disorders magenta 12, 3 3, 3 3, 0 3, 0 3, 0 -0.791 1.1 0.472 0.326 0.454 0.15 2.6 -1.62 4.23 0.701 0.154 0.198 0.183 10.1 -0.542 57.1 0.992 0.003 0.582 0.499 0.563 -0.798 21.7 0.971 0.013 0.45 0.432 0.468 PRS_PLINK_0.000251188643150958 300.3 Obsessive-compulsive disorders Both 0 6 5 mental disorders magenta 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 300.4 Dysthymic disorder Both 8 17 5 mental disorders magenta 17, 8 5, 2 4, 3 4, 2 4, 1 -0.988 1.3 0.446 0.351 0.372 0.000805 3.36 -1.23 2.87 0.667 0.176 0.291 1.71e-05 244 -2.95 6.21 0.635 0.197 0.0525 1.26e-06 459 1.37 5 0.785 0.105 3.92 0.00138 4.76 PRS_PLINK_0.000251188643150958 300.8 Acute reaction to stress Both 0 2 5 mental disorders magenta 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 300.9 Posttraumatic stress disorder Both 1 7 5 mental disorders magenta 7, 1 2, 0 2, 0 1, 1 2, 0 -0.0331 799 1 0 0.967 0.573 1.19 0.466 15300 1 0 1.59 6.45e-06 4.57e+11 PRS_PLINK_0.000251188643150958 301 Personality disorders Both 0 6 5 mental disorders magenta 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 301.2 Antisocial/borderline personality disorder Both 0 3 5 mental disorders magenta 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 302 Sexual and gender identity disorders Both 9 13 5 mental disorders magenta 13, 9 4, 3 3, 1 3, 3 3, 2 0.974 1.21 0.423 0.374 2.65 0.365 112 1.95 17.8 0.912 0.04 7.06 6.21 7.99 0.218 5.97 0.971 0.013 1.24 1.15 1.34 0.852 2.21 0.699 0.155 2.34 0.0763 78.3 PRS_PLINK_0.000251188643150958 302.1 Decreased libido Both 1 4 5 mental disorders magenta 4, 1 1, 0 1, 0 1, 0 1, 1 -0.366 10800000 1 0 0.694 0.0223 43.7 -0.0166 65.3 1 0 0.984 0.681 1.21 PRS_PLINK_0.000251188643150958 303 Psychogenic and somatoform disorders Both 8 16 5 mental disorders magenta 16, 8 4, 2 4, 1 4, 2 4, 3 -0.134 1.27 0.916 0.038 0.874 0.0215 14.8 -4.42 9.73 0.65 0.187 0.0121 8.82e-12 12400 -1.6 7.24 0.825 0.083 0.202 1.13e-05 6480 0.753 2.96 0.799 0.097 2.12 0.00902 292 PRS_PLINK_0.000251188643150958 303.1 Dissociative disorder Both 0 5 5 mental disorders magenta 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 303.3 Psychogenic disorder Both 8 16 5 mental disorders magenta 16, 8 4, 2 4, 1 4, 2 4, 3 -0.134 1.27 0.916 0.038 0.874 0.0215 14.8 -4.42 9.73 0.65 0.187 0.0121 8.82e-12 12400 -1.6 7.24 0.825 0.083 0.202 1.13e-05 6480 0.753 2.96 0.799 0.097 2.12 0.00902 292 PRS_PLINK_0.000251188643150958 303.31 Gastrointestinal malfunction arising from mental factors Both 1 5 5 mental disorders magenta 5, 1 2, 1 1, 0 1, 0 1, 0 -1.41 4150 1 0 0.244 1.75e-25 2.81e+10 0.214 5790 1 0 1.24 0.149 11.2 -1.52 19800 1 0 0.218 0.000952 126000 0.386 7850 1 0 1.47 0.208 27.6 PRS_PLINK_0.000251188643150958 303.4 Somatoform disorder Both 0 13 5 mental disorders magenta 13, 0 4 3 3 3 PRS_PLINK_0.000251188643150958 304 Adjustment reaction Both 10 18 5 mental disorders magenta 18, 10 5, 3 4, 2 4, 1 5, 4 0.613 0.699 0.38 0.42 1.85 0.55 6.94 1.18 1.77 0.506 0.296 3.25 0.248 202 -1.99 3.42 0.561 0.251 0.137 0.000134 18.3 1.26 2.22 0.57 0.244 3.54 0.0245 786 PRS_PLINK_0.000251188643150958 305.2 Eating disorder Both 1 10 5 mental disorders magenta 10, 1 3, 1 2, 0 2, 0 3, 0 -1.66 4.84 0.732 0.135 0.191 0.168 0.216 0.135 1280 1 0 1.14 0.271 11.9 -0.0111 475 1 0 0.989 0.793 1.16 -0.0299 1040 1 0 0.971 0.329 0.787 PRS_PLINK_0.000251188643150958 306 Other mental disorder Both 6 14 5 mental disorders magenta 14, 6 4, 3 3, 2 3, 1 4, 0 -1.75 2.24 0.436 0.361 0.174 0.000569 7.73 -0.89 2.91 0.76 0.119 0.411 0.368 0.505 0.718 10 0.943 0.025 2.05 1.52 3.42 -2.2 3.92 0.575 0.24 0.111 7.96e-05 22.7 PRS_PLINK_0.000251188643150958 306.1 Mental disorders durring/after pregnancy Female 1 6 5 mental disorders magenta 6, 1 2, 1 1, 0 1, 0 2, 0 -0.0384 34.7 0.999 0 0.962 0.464 1.72 -7.02 19900 1 0 0.000898 3.56e-18 25600000 0.217 10100 1 0 1.24 0.486 1.52 0.000673 1910 1 0 1 0.493 1.44 PRS_PLINK_0.000251188643150958 306.9 Tension headache Both 4 10 5 mental disorders magenta 10, 4 3, 1 2, 3 2, 0 3, 0 0.175 2.46 0.943 0.025 1.19 0.0096 360 1.57 449 0.997 0.001 4.82 4.22 5.08 0.686 12200 1 0 1.99 0.585 4510 -0.0659 65.9 0.999 0 0.936 0.454 2.26 PRS_PLINK_0.000251188643150958 312 Conduct disorders Both 2 1 5 mental disorders magenta 1, 2 -0.000676 467 1 0 0.999 0.997 1.05 PRS_PLINK_0.000251188643150958 312.3 Impulse control disorder Both 1 0 5 mental disorders magenta 0, 1 PRS_PLINK_0.000251188643150958 313 Pervasive developmental disorders Both 3 28 5 mental disorders magenta 28, 3 7, 0 7, 2 7, 0 7, 1 0.167 0.602 0.782 0.107 1.18 0.246 4.21 0.704 1.75 0.688 0.163 2.02 0.0308 149 -0.327 3.32 0.922 0.035 0.721 9.99e-05 124 PRS_PLINK_0.000251188643150958 313.1 Attention deficit hyperactivity disorder Both 3 25 5 mental disorders magenta 25, 3 7, 0 6, 2 6, 0 6, 1 0.121 0.685 0.86 0.066 1.13 0.0281 4.19 0.994 2.68 0.711 0.148 2.7 0.0226 3650 0.132 4.36 0.976 0.011 1.14 3.36e-05 849 PRS_PLINK_0.000251188643150958 313.2 Tics and stuttering Both 0 1 5 mental disorders magenta 1, 0 PRS_PLINK_0.000251188643150958 313.3 Autism Both 0 2 5 mental disorders magenta 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 315 Develomental delays and disorders Both 2 13 5 mental disorders magenta 13, 2 4, 0 3, 1 3, 0 3, 1 0.118 1.02 0.907 0.042 1.13 0.218 7.33 0.114 1030 1 0 1.12 0.707 1.78 -0.00534 356 1 0 0.995 0.131 7.38 PRS_PLINK_0.000251188643150958 315.1 Learning disorder Both 0 2 5 mental disorders magenta 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 315.2 Speech and language disorder Both 2 5 5 mental disorders magenta 5, 2 2, 1 1, 0 1, 1 1, 0 0.156 5400000 1 0 1.17 0.378 3.57 -0.415 14700 1 0 0.66 0.438 3.97 -1.94 3980 1 0 0.144 6.5e-12 154000 0.202 4430 1 0 1.22 0.497 2.27 PRS_PLINK_0.000251188643150958 316 Substance addiction and disorders Both 3 49 5 mental disorders magenta 49, 3 12, 0 12, 2 12, 0 12, 1 0.23 0.535 0.667 0.176 1.26 0.33 7.51 1.04 1.38 0.449 0.348 2.84 0.172 267 0.108 1.6 0.946 0.024 1.11 0.00497 79.9 PRS_PLINK_0.000251188643150958 316.1 Polyneuropathy due to drugs Both 0 4 5 mental disorders magenta 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 317 Alcohol-related disorders Both 0 36 5 mental disorders magenta 36, 0 9 9 9 9 PRS_PLINK_0.000251188643150958 317.1 Alcoholism Both 0 29 5 mental disorders magenta 29, 0 8 7 7 7 PRS_PLINK_0.000251188643150958 317.11 Alcoholic liver damage Both 0 7 5 mental disorders magenta 7, 0 2 2 1 2 PRS_PLINK_0.000251188643150958 318 Tobacco use disorder Both 9 51 5 mental disorders magenta 51, 9 12, 0 13, 6 12, 3 13, 0 -0.316 0.453 0.485 0.314 0.729 0.25 1.73 1.9 1.38 0.168 0.774 6.67 0.626 2730 1.2 1.58 0.446 0.351 3.33 0.144 283 PRS_PLINK_0.000251188643150958 320 Meningitis Both 1 3 6 neurological darkblue 3, 1 1, 0 1, 1 1, 0 1, 0 -0.295 19700 1 0 0.745 0.0133 5.25 3.15 1.12e+09 1 0 23.3 1.52e-06 24100000 PRS_PLINK_0.000251188643150958 323 Encephalitis Both 1 1 6 neurological darkblue 1, 1 0.00841 46.8 1 0 1.01 0.839 1.22 PRS_PLINK_0.000251188643150958 323.8 Encephalitis, non-infectious Both 1 1 6 neurological darkblue 1, 1 0.00841 46.8 1 0 1.01 0.839 1.22 PRS_PLINK_0.000251188643150958 324 Other CNS infection and poliomyelitis Both 0 5 6 neurological darkblue 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 327 Sleep disorders Both 24 38 6 neurological darkblue 38, 24 9, 2 9, 10 9, 8 10, 4 0.106 0.302 0.727 0.139 1.11 0.626 1.94 0.909 1.08 0.4 0.398 2.48 0.377 21.1 1.08 1.29 0.406 0.392 2.93 0.281 43.6 -0.303 1.49 0.839 0.076 0.739 0.0219 16.7 PRS_PLINK_0.000251188643150958 327.1 Hypersomnia Both 5 21 6 neurological darkblue 21, 5 6, 0 5, 1 5, 2 5, 2 0.631 0.766 0.41 0.387 1.88 0.332 11 0.759 5.99 0.899 0.046 2.14 8.96e-05 5190000 -0.0666 2.86 0.981 0.008 0.936 0.0122 105 0.801 6.79 0.906 0.043 2.23 4.45e-07 3.76e+11 PRS_PLINK_0.000251188643150958 327.3 Sleep apnea Both 21 37 6 neurological darkblue 37, 21 9, 0 9, 9 9, 7 9, 5 0.309 0.322 0.337 0.472 1.36 0.752 2.49 2.73 1.49 0.0663 1.179 15.4 1.5 1750 5.03 2.38 0.0348 1.458 153 2.96 281000 2.41 2 0.23 0.639 11.1 0.413 2030000 PRS_PLINK_0.000251188643150958 327.31 Central/nonobstroctive sleep apnea Both 2 5 6 neurological darkblue 5, 2 2, 0 1, 0 1, 0 1, 2 -0.0473 1120 1 0 0.954 0.701 1.2 -0.0104 396 1 0 0.99 0.762 1.1 PRS_PLINK_0.000251188643150958 327.32 Obstructive sleep apnea Both 18 35 6 neurological darkblue 35, 18 8, 0 9, 8 8, 5 9, 5 0.356 0.37 0.335 0.475 1.43 0.737 2.89 2.12 1.4 0.13 0.885 8.33 0.897 792 4.36 2.39 0.0683 1.166 77.9 1.92 37300 1.81 1.77 0.305 0.516 6.13 0.34 617 PRS_PLINK_0.000251188643150958 327.4 Insomnia Both 10 35 6 neurological darkblue 35, 10 8, 2 9, 2 8, 5 9, 1 -0.221 0.488 0.651 0.186 0.802 0.298 2.12 -0.484 1.46 0.741 0.13 0.616 0.0143 12.1 -0.328 1.5 0.827 0.083 0.721 0.0142 9.5 -1.43 1.78 0.424 0.373 0.24 1.05e-05 4.57 PRS_PLINK_0.000251188643150958 327.41 Organic or persistent insomnia Both 3 11 6 neurological darkblue 11, 3 3, 1 3, 0 2, 0 3, 2 1.11 1.94 0.565 0.248 3.05 0.191 268 0.18 2240 1 0 1.2 0.529 1.25 -0.00123 67.8 1 0 0.999 0.572 1.68 0.117 872 1 0 1.12 0.95 2.03 PRS_PLINK_0.000251188643150958 327.5 Parasomnia Both 3 9 6 neurological darkblue 9, 3 3, 0 2, 0 2, 1 2, 2 1.35 2.11 0.523 0.282 3.85 0.196 850 -0.00602 695 1 0 0.994 0.282 1.22 -0.0211 552 1 0 0.979 0.65 1.43 PRS_PLINK_0.000251188643150958 327.6 Circadian rhythm sleep disorder Both 0 6 6 neurological darkblue 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 327.7 Sleep related movement disorders Both 3 21 6 neurological darkblue 21, 3 6, 2 5, 0 5, 0 5, 1 -0.392 0.787 0.618 0.209 0.675 0.018 2.41 1.23 7.79 0.874 0.058 3.44 0.000124 143000 -0.92 3.47 0.791 0.102 0.398 2.15e-05 56.7 -2.48 2.69 0.356 0.449 0.0833 0.00059 4.16 PRS_PLINK_0.000251188643150958 327.71 Restless legs syndrome Both 2 17 6 neurological darkblue 17, 2 5, 2 4, 0 4, 0 4, 0 -0.461 0.936 0.622 0.206 0.631 0.00748 3.32 7.1e-12 23 1 0 1 3.68e-08 13600000 -1.66 6.56 0.8 0.097 0.189 3.68e-05 617 -2.27 10.6 0.83 0.081 0.104 1.65e-05 784 PRS_PLINK_0.000251188643150958 327.72 Sleep related leg cramps Both 0 1 6 neurological darkblue 1, 0 PRS_PLINK_0.000251188643150958 331 Other cerebral degenerations Both 2 7 6 neurological darkblue 7, 2 2, 1 2, 0 1, 0 2, 1 0.65 27.7 0.981 0.008 1.92 0.343 11.1 0.00321 2000 1 0 1 0.506 3.08 0.00325 61.5 1 0 1 0.912 1.06 0.106 717 1 0 1.11 0.478 13.6 PRS_PLINK_0.000251188643150958 331.1 Hydrocephalus Both 0 1 6 neurological darkblue 1, 0 PRS_PLINK_0.000251188643150958 331.9 Cerebral degeneration, unspecified Both 2 3 6 neurological darkblue 3, 2 1, 1 1, 0 0, 1 1, 0 0.113 2660 1 0 1.12 0.551 4.58 -0.00586 45.3 1 0 0.994 0.949 1.02 -0.00103 79.8 1 0 0.999 0.984 1.02 0.0115 40.1 1 0 1.01 0.967 1.07 PRS_PLINK_0.000251188643150958 332 Parkinson's disease Both 0 1 6 neurological darkblue 1, 0 PRS_PLINK_0.000251188643150958 333 Extrapyramidal disease and abnormal movement disorders Both 6 27 6 neurological darkblue 27, 6 7, 5 7, 1 6, 0 7, 0 -0.439 0.497 0.376 0.425 0.644 0.191 1.57 -1.63 1.79 0.361 0.442 0.195 9.14e-07 2.88 -0.671 1.97 0.733 0.135 0.511 0.00349 13.5 -1.95 1.7 0.252 0.599 0.142 0.0031 39.6 PRS_PLINK_0.000251188643150958 333.1 Essential tremor Both 1 6 6 neurological darkblue 6, 1 2, 1 1, 0 1, 0 2, 0 0.00851 1730 1 0 1.01 0.697 0.892 -0.0279 18800 1 0 0.972 0.82 2.52 0.00265 46 1 0 1 0.946 1.07 -0.087 3950 1 0 0.917 0.489 1.57 PRS_PLINK_0.000251188643150958 333.2 Myoclonus Both 0 2 6 neurological darkblue 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 333.4 Torsion dystonia Both 0 4 6 neurological darkblue 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 333.8 Other degenerative diseases of the basal ganglia Both 1 1 6 neurological darkblue 1, 1 0.0121 52.9 1 0 1.01 0.272 1.07 PRS_PLINK_0.000251188643150958 334 Degenerative disease of the spinal cord Both 0 11 6 neurological darkblue 11, 0 3 3 2 3 PRS_PLINK_0.000251188643150958 335 Multiple sclerosis Both 1 3 6 neurological darkblue 3, 1 1, 0 1, 0 1, 1 1, 0 0.0298 1980 1 0 1.03 0.511 1.27 -0.00235 77.6 1 0 0.998 0.914 1.08 PRS_PLINK_0.000251188643150958 337 Disorders of the autonomic nervous system Both 8 14 6 neurological darkblue 14, 8 4, 0 3, 4 3, 2 4, 2 0.43 0.918 0.639 0.194 1.54 0.327 13.3 1.31 4.2 0.754 0.122 3.72 0.00875 9000 0.619 5.07 0.903 0.044 1.86 1.78 1.95 0.649 46.3 0.989 0.005 1.91 9.31e-05 39900 PRS_PLINK_0.000251188643150958 337.1 Peripheral autonomic neuropathy Both 6 11 6 neurological darkblue 11, 6 3, 2 3, 1 2, 0 3, 3 0.641 1.2 0.593 0.227 1.9 0.132 2.24 -1.35 118 0.991 0.004 0.26 0.684 0.781 -5.04 151 0.973 0.012 0.00646 8.21e-09 0.00796 -0.635 3.73 0.865 0.063 0.53 0.000106 570 PRS_PLINK_0.000251188643150958 338 Pain Both 36 27 6 neurological darkblue 27, 36 6, 5 7, 13 6, 5 7, 13 0.377 0.307 0.219 0.659 1.46 0.854 2.71 0.232 0.945 0.806 0.093 1.26 0.236 6.86 1.87 1.67 0.264 0.579 6.49 0.465 1860 1.55 1.24 0.212 0.673 4.72 0.574 103 PRS_PLINK_0.000251188643150958 338.1 Acute pain Both 23 27 6 neurological darkblue 27, 23 6, 3 7, 6 6, 4 7, 10 0.465 0.355 0.19 0.722 1.59 0.878 3.33 0.166 1.47 0.91 0.041 1.18 0.0988 18.7 1.98 1.69 0.243 0.614 7.21 0.559 341 2.4 1.5 0.109 0.962 11 1.04 645 PRS_PLINK_0.000251188643150958 338.2 Chronic pain Both 21 27 6 neurological darkblue 27, 21 6, 3 7, 12 6, 3 7, 3 0.0871 0.393 0.825 0.084 1.09 0.539 2.24 0.843 1.1 0.444 0.352 2.32 0.355 18.5 0.469 2.4 0.845 0.073 1.6 0.0199 123 0.796 2.19 0.717 0.145 2.22 0.000973 274 PRS_PLINK_0.000251188643150958 339 Other headache syndromes Both 23 36 6 neurological darkblue 36, 23 9, 5 9, 7 9, 3 9, 8 -0.0227 0.314 0.942 0.026 0.978 0.538 1.72 1.14 1.13 0.315 0.501 3.12 0.47 31.1 -0.409 1.47 0.781 0.107 0.664 0.0172 10.9 0.354 0.985 0.719 0.143 1.42 0.238 8.98 PRS_PLINK_0.000251188643150958 340 Migraine Both 19 35 6 neurological darkblue 35, 19 9, 4 9, 1 8, 5 9, 8 0.00872 0.332 0.979 0.009 1.01 0.531 1.84 -1.38 1.34 0.303 0.518 0.252 0.00902 2.26 1.03 1.26 0.41 0.387 2.81 0.323 44 0.502 1.12 0.655 0.184 1.65 0.237 14.2 PRS_PLINK_0.000251188643150958 340.1 Migrain with aura Both 8 25 6 neurological darkblue 25, 8 7, 3 6, 1 6, 1 6, 3 0.0306 0.675 0.964 0.016 1.03 0.276 3.64 -1.02 1.6 0.526 0.279 0.362 0.00976 4.27 -0.984 2.13 0.643 0.191 0.374 0.00283 27.3 -0.22 1.64 0.893 0.049 0.802 0.0426 18.8 PRS_PLINK_0.000251188643150958 342 Hemiplegia Both 0 5 6 neurological darkblue 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 343 Infantile cerebral palsy Both 0 1 6 neurological darkblue 1, 0 PRS_PLINK_0.000251188643150958 344 Other paralytic syndromes Both 1 6 6 neurological darkblue 6, 1 2, 0 1, 1 1, 0 2, 0 0.76 4080000 1 0 2.14 0.0625 125 0.00761 1820 1 0 1.01 0.761 4.19 PRS_PLINK_0.000251188643150958 345 Epilepsy, recurrent seizures, convulsions Both 5 34 6 neurological darkblue 34, 5 9, 2 8, 2 8, 0 9, 1 0.144 0.609 0.813 0.09 1.16 0.325 5.58 0.723 1.43 0.613 0.212 2.06 0.155 39 -0.978 1.99 0.623 0.205 0.376 2.67e-06 10.2 0.101 1.41 0.943 0.026 1.11 0.0569 18.8 PRS_PLINK_0.000251188643150958 345.1 Epilepsy Both 1 13 6 neurological darkblue 13, 1 4, 0 3, 1 3, 0 3, 0 -0.558 1.64 0.734 0.134 0.573 0.00027 6.54 -0.116 296 1 0 0.89 0.289 1.32 PRS_PLINK_0.000251188643150958 345.11 Generalized convulsive epilepsy Both 1 3 6 neurological darkblue 3, 1 1, 1 1, 0 1, 0 1, 1 0.0562 5970 1 0 1.06 0.214 11.3 0.134 10200 1 0 1.14 0.293 5.17 0.526 11900 1 0 1.69 0.252 97.3 PRS_PLINK_0.000251188643150958 345.12 Partial epilepsy Both 1 6 6 neurological darkblue 6, 1 2, 1 1, 0 1, 0 2, 0 -0.0433 1320 1 0 0.958 0.243 4.21 0.255 3980 1 0 1.29 0.568 8.9 -0.482 18500 1 0 0.617 0.0153 3.35 -5.01 6230 0.999 0 0.00666 2.32e-22 4.87e+13 PRS_PLINK_0.000251188643150958 345.3 Convulsions Both 5 32 6 neurological darkblue 32, 5 8, 2 8, 2 8, 1 8, 0 0.225 0.621 0.717 0.144 1.25 0.362 6.64 0.234 1.54 0.88 0.056 1.26 0.0269 22.4 -0.605 2.21 0.784 0.105 0.546 0.000734 23.2 -0.786 1.76 0.655 0.184 0.455 0.00606 9.49 PRS_PLINK_0.000251188643150958 346 Abnormal findings on study of brain and/or nervous system Both 0 5 6 neurological darkblue 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 346.1 Nonspecific abnormal findings on radiological and other examination of skull and head Both 3 12 6 neurological darkblue 12, 3 3, 2 3, 0 3, 1 3, 0 -0.456 1.09 0.676 0.17 0.634 0.0341 3.38 0.0468 132 1 0 1.05 1.23 2.49 -1.12 36.3 0.975 0.011 0.326 0.106 0.0911 -0.707 1130 1 0 0.493 0.0213 0.089 PRS_PLINK_0.000251188643150958 346.2 Nonspecific abnormal results of function study of brain and central nervous system Both 0 2 6 neurological darkblue 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 347 Cataplexy and narcolepsy Both 0 1 6 neurological darkblue 1, 0 PRS_PLINK_0.000251188643150958 348 Other conditions of brain Both 2 17 6 neurological darkblue 17, 2 5, 0 4, 2 4, 0 4, 0 0.064 0.885 0.942 0.026 1.07 0.118 22.4 1.07 4.67 0.818 0.087 2.93 0.00209 10800 PRS_PLINK_0.000251188643150958 348.2 Cerebral edema and compression of brain Both 1 10 6 neurological darkblue 10, 1 3, 0 2, 1 2, 0 3, 0 0.179 2.45 0.942 0.026 1.2 0.0161 63.9 0.37 2850 1 0 1.45 0.407 5.21 PRS_PLINK_0.000251188643150958 348.4 Cerebral cysts Both 0 4 6 neurological darkblue 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 348.7 Coma Both 0 2 6 neurological darkblue 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 348.8 Encephalopathy, not elsewhere classified Both 0 6 6 neurological darkblue 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 348.9 Other conditions of brain, NOS Both 3 20 6 neurological darkblue 20, 3 5, 0 5, 0 5, 2 5, 1 0.797 0.736 0.279 0.555 2.22 0.694 223 0.759 1.93 0.694 0.158 2.14 2.05 2.39 2.27 979 0.998 0.001 9.66 8.18 11.4 PRS_PLINK_0.000251188643150958 349 Other and unspecified disorders of the nervous system Both 1 10 6 neurological darkblue 10, 1 3, 0 2, 0 2, 1 3, 0 0.309 1 0.758 0.12 1.36 0.307 13.8 0.000132 1110 1 0 1 0.547 1.91 PRS_PLINK_0.000251188643150958 350 Abnormal movement Both 12 46 6 neurological darkblue 46, 12 11, 0 11, 7 11, 2 12, 3 0.618 0.457 0.176 0.754 1.86 0.746 5.02 3.19 1.95 0.102 0.992 24.4 1.28 59300 -0.298 1.79 0.868 0.062 0.742 0.00424 202 2.2 1.58 0.164 0.785 9.04 0.602 41500000 PRS_PLINK_0.000251188643150958 350.1 Abnormal involuntary movements Both 5 33 6 neurological darkblue 33, 5 9, 0 8, 3 8, 1 8, 1 0.923 0.78 0.237 0.625 2.52 0.61 61.9 0.536 1.83 0.77 0.114 1.71 0.00338 116 1.34 2.02 0.506 0.296 3.83 0.0188 683 0.182 2.29 0.936 0.029 1.2 0.0011 37000 PRS_PLINK_0.000251188643150958 350.2 Abnormality of gait Both 8 28 6 neurological darkblue 28, 8 7, 0 7, 6 7, 1 7, 1 -0.131 0.74 0.86 0.066 0.877 0.175 3.91 2.39 1.69 0.157 0.803 10.9 0.795 58100 -0.0281 1.71 0.987 0.006 0.972 0.0103 51.1 1.61 3.49 0.644 0.191 5.02 0.015 1800 PRS_PLINK_0.000251188643150958 350.3 Lack of coordination Both 3 12 6 neurological darkblue 12, 3 3, 0 3, 2 3, 0 3, 1 1.07 1.59 0.502 0.299 2.9 0.261 991 0.0108 89.8 1 0 1.01 0.932 1.16 -0.0483 672 1 0 0.953 0.581 1.48 PRS_PLINK_0.000251188643150958 350.5 Abnormal reflex Both 0 3 6 neurological darkblue 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 350.6 Disturbances of sensation of smell and taste Both 0 9 6 neurological darkblue 9, 0 3 2 2 2 PRS_PLINK_0.000251188643150958 351 Other peripheral nerve disorders Both 18 39 6 neurological darkblue 39, 18 9, 1 10, 5 9, 7 10, 5 0.513 0.399 0.198 0.702 1.67 0.825 3.8 1.11 1.32 0.402 0.395 3.02 0.295 291 2.66 1.73 0.125 0.905 14.3 0.817 1100 1.75 1.44 0.225 0.647 5.74 0.585 274 PRS_PLINK_0.000251188643150958 352 Disorders of other cranial nerves Both 2 13 6 neurological darkblue 13, 2 3, 0 3, 1 3, 0 3, 1 0.852 2.06 0.679 0.168 2.34 0.0389 1050 0.517 528 0.999 0 1.68 2.2 16.8 0.105 3180000 1 0 1.11 0.38 3.09 PRS_PLINK_0.000251188643150958 352.1 Trigeminal nerve disorders [CN5] Both 1 7 6 neurological darkblue 7, 1 1, 0 2, 0 1, 1 2, 0 0.0715 461 1 0 1.07 0.444 2.07 -9.26 50700 1 0 9.54e-05 4.53e-17 10500000 PRS_PLINK_0.000251188643150958 352.2 Facial nerve disorders [CN7] Both 1 5 6 neurological darkblue 5, 1 2, 0 1, 0 1, 0 1, 1 -0.027 2110 1 0 0.973 0.495 1.54 -0.00389 28.7 1 0 0.996 0.869 1.04 PRS_PLINK_0.000251188643150958 353 Nerve root and plexus disorders Both 3 33 6 neurological darkblue 33, 3 8, 1 8, 1 8, 0 8, 1 0.289 0.601 0.631 0.2 1.33 0.423 8.53 0.405 1.7 0.811 0.091 1.5 0.0551 48.7 -1.55 1.93 0.422 0.375 0.212 0.00129 7.83 -0.575 1.78 0.746 0.127 0.563 5.46e-05 12.2 PRS_PLINK_0.000251188643150958 353.1 Nerve plexus lesions Both 0 2 6 neurological darkblue 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 355 Complex regional/central pain syndrome Both 0 6 6 neurological darkblue 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 355.1 Chronic pain syndrome Both 0 11 6 neurological darkblue 11, 0 3 3 2 3 PRS_PLINK_0.000251188643150958 356 Hereditary and idiopathic peripheral neuropathy Both 13 19 6 neurological darkblue 19, 13 5, 4 5, 3 4, 1 5, 5 0.213 0.652 0.744 0.128 1.24 0.412 4.69 -1.15 2.05 0.573 0.242 0.316 6.48e-05 9.91 0.21 2.27 0.926 0.033 1.23 0.0394 81500 0.346 1.73 0.841 0.075 1.41 0.0896 207 PRS_PLINK_0.000251188643150958 357 Inflammatory and toxic neuropathy Both 14 23 6 neurological darkblue 23, 14 6, 2 6, 5 5, 2 6, 5 0.535 0.657 0.416 0.381 1.71 0.493 7.83 1.51 1.66 0.363 0.44 4.55 0.24 1850 0.436 1.54 0.777 0.11 1.55 0.0417 35 0.894 1.72 0.603 0.22 2.44 0.119 84 PRS_PLINK_0.000251188643150958 358 Myoneural disorders Both 3 5 6 neurological darkblue 5, 3 2, 0 1, 0 1, 1 1, 2 0.00846 441 1 0 1.01 0.373 8.94 -0.118 66300 1 0 0.889 5.87e-06 45.2 0.224 19500 1 0 1.25 0.134 1.83 PRS_PLINK_0.000251188643150958 359 Muscular dystrophies and other myopathies Both 5 12 6 neurological darkblue 12, 5 3, 2 3, 0 3, 1 3, 2 -0.421 1.49 0.777 0.109 0.656 0.000405 7.54 -0.189 289 0.999 0 0.828 0.343 0.665 2.59 12.5 0.836 0.078 13.3 22.5 29.2 0.208 23.7 0.993 0.003 1.23 0.868 1.71 PRS_PLINK_0.000251188643150958 359.2 Myopathy Both 5 10 6 neurological darkblue 10, 5 3, 1 2, 1 2, 1 3, 2 -0.247 1.41 0.861 0.065 0.781 0.000734 12.3 0.0976 736 1 0 1.1 0.619 2.24 0.13 601 1 0 1.14 0.996 1.51 0.759 3900000 1 0 2.14 0.951 6.25 PRS_PLINK_0.000251188643150958 360.2 Progressive myopia Both 0 1 7 sense organs darkseagreen4 1, 0 PRS_PLINK_0.000251188643150958 361 Retinal detachments and defects Both 0 10 7 sense organs darkseagreen4 10, 0 3 2 2 3 PRS_PLINK_0.000251188643150958 361.1 Retinal detachment with retinal defect Both 0 6 7 sense organs darkseagreen4 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 362 Other retinal disorders Both 11 16 7 sense organs darkseagreen4 16, 11 4, 2 4, 1 4, 5 4, 3 0.084 0.705 0.905 0.043 1.09 0.303 4.04 -1.13 2.86 0.693 0.159 0.324 0.00314 76 0.0816 1.65 0.961 0.017 1.08 0.902 1.3 -4.33 3.49 0.215 0.667 0.0132 1.83e-05 1.47 PRS_PLINK_0.000251188643150958 362.2 Degeneration of macula and posterior pole of retina Both 3 10 7 sense organs darkseagreen4 10, 3 3, 0 2, 1 2, 1 3, 1 -0.00509 1.72 0.998 0.001 0.995 0.0203 16.7 -0.0207 626 1 0 0.979 0.575 1.52 -2.73e-05 571 1 0 1 0.652 1.79 1.04 118 0.993 0.003 2.82 1.24e-08 4180000 PRS_PLINK_0.000251188643150958 362.21 Macular degeneration, dry Both 0 2 7 sense organs darkseagreen4 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 362.22 Macular degeneration, wet Both 0 1 7 sense organs darkseagreen4 1, 0 PRS_PLINK_0.000251188643150958 362.23 Cystoid macular degeneration of retina Both 0 4 7 sense organs darkseagreen4 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 362.26 Macular puckering of retina Both 2 7 7 sense organs darkseagreen4 7, 2 2, 0 2, 0 1, 1 2, 1 0.304 168 0.999 0.001 1.35 0.00619 26.4 -0.00413 261 1 0 0.996 0.85 1.17 0.022 1320 1 0 1.02 0.639 1.72 PRS_PLINK_0.000251188643150958 362.27 Drusen (degenerative) of retina Both 1 3 7 sense organs darkseagreen4 3, 1 1, 1 1, 0 1, 0 1, 1 0.133 16500 1 0 1.14 0.00935 180 0.0546 1610 1 0 1.06 0.842 1.69 0.242 5010 1 0 1.27 0.572 7.59 PRS_PLINK_0.000251188643150958 362.29 Macular degeneration (senile) of retina NOS Both 3 10 7 sense organs darkseagreen4 10, 3 3, 0 2, 1 2, 1 3, 1 -0.00509 1.72 0.998 0.001 0.995 0.0203 16.7 -0.0207 626 1 0 0.979 0.575 1.52 -2.73e-05 571 1 0 1 0.652 1.79 1.04 118 0.993 0.003 2.82 1.24e-08 4180000 PRS_PLINK_0.000251188643150958 362.3 Other nondiabetic retinopathy Both 3 9 7 sense organs darkseagreen4 9, 3 3, 0 2, 3 2, 0 2, 0 -0.8 2.66 0.764 0.117 0.449 0.00683 22.8 0.677 661 0.999 0 1.97 2.94 78.8 PRS_PLINK_0.000251188643150958 362.31 Separation of retinal layers Both 0 4 7 sense organs darkseagreen4 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 362.4 Retinal vascular changes and abnomalities Both 4 3 7 sense organs darkseagreen4 3, 4 1, 4 1, 0 1, 0 1, 4 -0.00585 376 1 0 0.994 0.67 1.26 0.188 5640 1 0 1.21 0.198 4.89 -0.00658 198 1 0 0.993 0.129 2.95 PRS_PLINK_0.000251188643150958 362.6 Peripheral retinal degenerations Both 2 4 7 sense organs darkseagreen4 4, 2 1, 1 1, 1 1, 0 1, 0 -0.199 482 1 0 0.819 0.396 1.66 -0.653 14700 1 0 0.521 0.191 1.54 -0.0291 177 1 0 0.971 0.833 1.23 -0.00132 62.7 1 0 0.999 0.967 1.02 PRS_PLINK_0.000251188643150958 362.7 Hereditary retinal dystrophies Both 1 0 7 sense organs darkseagreen4 0, 1 PRS_PLINK_0.000251188643150958 362.8 Retinal hemorrhage/ischemia Both 0 2 7 sense organs darkseagreen4 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 362.9 Retinal edema Both 1 4 7 sense organs darkseagreen4 4, 1 1, 1 1, 0 1, 0 1, 0 -0.0938 5380 1 0 0.91 0.847 2.05 0.0564 73 0.999 0 1.06 0.925 2.75 0.0195 55 1 0 1.02 0.904 1.14 0.0174 54.1 1 0 1.02 0.855 1.17 PRS_PLINK_0.000251188643150958 363 Chorioretinal inflammations, scars, and other disorders of choroid Both 0 7 7 sense organs darkseagreen4 7, 0 2 2 1 2 PRS_PLINK_0.000251188643150958 363.3 Chorioretinal scars Both 0 5 7 sense organs darkseagreen4 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 364 Corneal opacity and other disorders of cornea Both 4 15 7 sense organs darkseagreen4 15, 4 4, 0 4, 1 3, 2 4, 1 0.216 1.01 0.83 0.081 1.24 0.115 8.31 0.929 53.3 0.986 0.006 2.53 2.44e-05 273000 0.955 5.52 0.863 0.064 2.6 0.103 138 -0.0324 291 1 0 0.968 1.17 1.39 PRS_PLINK_0.000251188643150958 364.1 Corneal opacity Both 2 8 7 sense organs darkseagreen4 8, 2 2, 1 2, 1 2, 0 2, 0 1.21 51.2 0.981 0.008 3.35 3.1 3.61 0.438 2760 1 0 1.55 0.229 2.39 0.0493 674 1 0 1.05 0.225 14.1 -1.5 170 0.993 0.003 0.222 0.000301 58.2 PRS_PLINK_0.000251188643150958 364.2 Corneal edema Both 1 2 7 sense organs darkseagreen4 2, 1 1, 0 0, 1 1, 0 1, 0 -0.397 6.58e+08 1 0 0.673 0.000113 1440 -0.0346 26.6 0.999 0 0.966 0.552 113 PRS_PLINK_0.000251188643150958 364.4 Corneal degenerations Both 3 5 7 sense organs darkseagreen4 5, 3 2, 0 1, 0 1, 1 1, 2 0.128 16.5 0.994 0.003 1.14 0.116 1.17 0.000955 63.5 1 0 1 0.917 1.08 0.833 52000 1 0 2.3 9.68e-59 2.55e+36 PRS_PLINK_0.000251188643150958 364.5 Corneal dystrophy Both 1 4 7 sense organs darkseagreen4 4, 1 1, 0 1, 0 1, 1 1, 0 -0.00168 144 1 0 0.998 0.957 1.04 -0.0856 4390 1 0 0.918 0.355 1.35 PRS_PLINK_0.000251188643150958 365 Glaucoma Both 10 23 7 sense organs darkseagreen4 23, 10 6, 3 6, 0 5, 4 6, 3 0.0999 0.573 0.862 0.065 1.11 0.361 3.34 0.0204 138 1 0 1.02 0.886 1.55 0.326 1.42 0.819 0.087 1.39 0.109 21.2 0.449 1.38 0.746 0.127 1.57 0.106 119 PRS_PLINK_0.000251188643150958 365.1 Open-angle glaucoma Both 3 6 7 sense organs darkseagreen4 6, 3 2, 0 1, 2 1, 1 2, 0 3.41 45.8 0.941 0.027 30.3 219 191 -0.0491 5930 1 0 0.952 0.527 2.24 -0.235 6210 1 0 0.79 0.339 1.81 PRS_PLINK_0.000251188643150958 365.11 Primary open angle glaucoma Both 1 3 7 sense organs darkseagreen4 3, 1 1, 1 1, 0 1, 0 1, 1 -0.0287 974 1 0 0.972 0.826 1.21 -0.0389 2340 1 0 0.962 0.709 1.4 -0.0189 2840 1 0 0.981 0.964 1.07 PRS_PLINK_0.000251188643150958 365.2 Primary angle-closure glaucoma Both 0 2 7 sense organs darkseagreen4 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 366 Cataract Both 22 22 7 sense organs darkseagreen4 22, 22 6, 3 5, 2 5, 5 6, 12 0.408 0.525 0.436 0.36 1.5 0.545 4.76 -1.48 2.6 0.57 0.244 0.228 7.13e-05 127 0.487 1.8 0.787 0.104 1.63 0.00384 47.2 1.41 1.65 0.391 0.408 4.11 0.172 1770 PRS_PLINK_0.000251188643150958 366.1 Nonsenile Cataract Both 2 0 7 sense organs darkseagreen4 0, 2 PRS_PLINK_0.000251188643150958 366.2 Senile cataract Both 19 18 7 sense organs darkseagreen4 18, 19 5, 3 4, 3 4, 3 5, 10 0.865 0.716 0.227 0.643 2.37 0.644 16.2 -0.739 3.08 0.81 0.091 0.478 4.01e-06 844 1.7 2.85 0.551 0.259 5.47 0.00181 19300 0.645 1.48 0.664 0.178 1.91 0.131 249 PRS_PLINK_0.000251188643150958 367 Disorders of refraction and accommodation; blindness and low vision Both 25 39 7 sense organs darkseagreen4 39, 25 9, 5 10, 4 9, 9 10, 7 0.24 0.329 0.466 0.332 1.27 0.683 2.38 -0.763 1.19 0.523 0.282 0.466 0.0422 3.75 0.559 1.03 0.587 0.231 1.75 0.281 12.7 -0.013 1.09 0.991 0.004 0.987 0.126 8.64 PRS_PLINK_0.000251188643150958 367.1 Myopia Both 22 36 7 sense organs darkseagreen4 36, 22 8, 5 9, 6 9, 6 9, 5 0.018 0.37 0.961 0.017 1.02 0.491 2.03 0.145 1.15 0.9 0.046 1.16 0.138 9.26 0.402 1.2 0.737 0.133 1.49 0.127 17.9 -0.804 1.38 0.561 0.251 0.448 0.0119 6.36 PRS_PLINK_0.000251188643150958 367.2 Astigmatism Both 12 32 7 sense organs darkseagreen4 32, 12 7, 1 8, 0 8, 7 8, 4 0.613 0.482 0.203 0.692 1.85 0.745 6.07 -1.29 1.76 0.463 0.334 0.274 0.000281 4.47 1.41 1.45 0.332 0.479 4.1 0.378 492 -0.079 1.84 0.966 0.015 0.924 0.0038 28.8 PRS_PLINK_0.000251188643150958 367.8 Hypermetropia Both 0 17 7 sense organs darkseagreen4 17, 0 5 4 4 4 PRS_PLINK_0.000251188643150958 367.9 Blindness and low vision Both 3 14 7 sense organs darkseagreen4 14, 3 4, 0 3, 3 3, 0 4, 0 1.79 1.92 0.351 0.455 5.99 0.302 226000 1.44 7.3 0.843 0.074 4.24 3.63 4.79 PRS_PLINK_0.000251188643150958 368 Visual disturbances Both 15 46 7 sense organs darkseagreen4 46, 15 11, 5 11, 4 11, 3 12, 3 -0.182 0.371 0.625 0.204 0.834 0.403 1.66 -0.233 1.06 0.826 0.083 0.792 0.0776 5.57 -0.701 1.19 0.555 0.256 0.496 0.0222 4.29 -0.669 1.08 0.536 0.271 0.512 0.0466 4.28 PRS_PLINK_0.000251188643150958 368.1 Amblyopia Both 2 11 7 sense organs darkseagreen4 11, 2 3, 0 3, 0 2, 1 3, 1 -0.778 2.06 0.706 0.151 0.459 0.00456 88.4 -0.321 11400 1 0 0.726 0.067 2.96 -0.164 2790 1 0 0.849 0.374 1.73 PRS_PLINK_0.000251188643150958 368.2 Diplopia and disorders of binocular vision Both 7 13 7 sense organs darkseagreen4 13, 7 4, 1 3, 0 3, 3 3, 3 0.891 0.904 0.325 0.489 2.44 0.594 18 0.0091 27.3 1 0 1.01 0.939 1.1 0.262 2.84 0.926 0.033 1.3 1.09 1.42 0.0983 4.26 0.982 0.008 1.1 1 1.37 PRS_PLINK_0.000251188643150958 368.3 Anisometropia Both 0 3 7 sense organs darkseagreen4 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 368.4 Visual field defects Both 3 12 7 sense organs darkseagreen4 12, 3 3, 1 3, 0 3, 1 3, 1 -2.07 2.11 0.326 0.487 0.126 1.39e-05 4.01 0.0249 2370000 1 0 1.03 0.214 14.3 0.162 1390 1 0 1.18 0.862 2.22 -0.126 1340000 1 0 0.882 0.399 1.9 PRS_PLINK_0.000251188643150958 368.9 Subjective visual disturbances Both 3 11 7 sense organs darkseagreen4 11, 3 2, 0 3, 0 2, 2 3, 1 -0.15 1.3 0.908 0.042 0.861 0.0493 42.4 0.0288 12600 1 0 1.03 0.618 1.83 0.0496 3290 1 0 1.05 0.57 2.04 PRS_PLINK_0.000251188643150958 368.91 Psychophysical visual disturbances Both 0 1 7 sense organs darkseagreen4 1, 0 PRS_PLINK_0.000251188643150958 369 Infection of the eye Both 8 38 7 sense organs darkseagreen4 38, 8 9, 0 9, 3 9, 1 10, 4 0.15 0.479 0.754 0.122 1.16 0.396 4.48 1.27 1.82 0.487 0.312 3.54 0.046 1010000 0.0529 1.64 0.974 0.011 1.05 0.0495 110 -0.143 2.31 0.951 0.022 0.867 0.000631 1580 PRS_PLINK_0.000251188643150958 369.2 Eye infection, viral Both 1 11 7 sense organs darkseagreen4 11, 1 3, 0 3, 0 2, 0 3, 1 -0.138 1.41 0.922 0.035 0.871 0.0953 11.9 0.227 6790 1 0 1.26 0.0177 20.3 PRS_PLINK_0.000251188643150958 369.5 Conjunctivitis, infectious Both 6 32 7 sense organs darkseagreen4 32, 6 7, 0 8, 3 8, 1 8, 2 0.00557 0.484 0.991 0.004 1.01 0.29 2.73 1.15 1.69 0.495 0.306 3.17 0.0747 276 -0.197 2.77 0.943 0.025 0.821 0.00266 206 0.242 2.59 0.925 0.034 1.27 0.00011 3380 PRS_PLINK_0.000251188643150958 370 Keratitis Both 4 18 7 sense organs darkseagreen4 18, 4 5, 1 4, 0 4, 1 5, 2 0.0871 0.716 0.903 0.044 1.09 0.188 5.22 -2.58 29.7 0.931 0.031 0.076 0.0429 0.0616 -1.48 9.61 0.878 0.057 0.227 0.208 0.246 -0.0266 2.35 0.991 0.004 0.974 0.0171 33.4 PRS_PLINK_0.000251188643150958 370.1 Corneal ulcer Both 0 6 7 sense organs darkseagreen4 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 370.2 Superficial keratitis Both 2 7 7 sense organs darkseagreen4 7, 2 2, 0 2, 0 1, 1 2, 1 0.662 31.1 0.983 0.007 1.94 1.43 2.05 0.047 9470 1 0 1.05 0.216 9.44 0.0405 4600 1 0 1.04 0.211 3.9 PRS_PLINK_0.000251188643150958 370.3 Keratoconjunctivitis Both 2 8 7 sense organs darkseagreen4 8, 2 2, 1 2, 0 2, 1 2, 0 0.115 2140 1 0 1.12 0.532 1.46 -0.0523 8780 1 0 0.949 0.048 6.22 0.163 13700 1 0 1.18 0.0064 16.9 0.442 25900 1 0 1.56 0.122 73.2 PRS_PLINK_0.000251188643150958 370.31 Keratoconjunctivitis sicca Both 0 4 7 sense organs darkseagreen4 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 371 Inflammation of the eye Both 11 35 7 sense organs darkseagreen4 35, 11 8, 2 9, 2 8, 4 9, 3 0.173 0.409 0.673 0.172 1.19 0.556 2.61 -0.0644 1.49 0.966 0.015 0.938 0.0202 10.8 -0.0688 1.43 0.962 0.017 0.934 0.0296 242 -0.141 2.51 0.955 0.02 0.869 0.00222 672 PRS_PLINK_0.000251188643150958 371.1 Uveitis, noninfectious or NOS Both 2 9 7 sense organs darkseagreen4 9, 2 3, 1 2, 0 2, 0 2, 1 0.0963 117 0.999 0 1.1 1.19 1.82 0.0916 3250000 1 0 1.1 0.396 3.64 0.41 33700 1 0 1.51 0.158 1.81 0.0385 3020 1 0 1.04 0.534 1.76 PRS_PLINK_0.000251188643150958 371.2 Conjunctivitis, noninfectious Both 1 16 7 sense organs darkseagreen4 16, 1 3, 1 4, 0 4, 0 4, 0 -0.145 0.906 0.873 0.059 0.865 0.172 9.92 -1.91 13.5 0.888 0.052 0.148 0.143 0.153 -0.717 4.99 0.886 0.053 0.488 0.483 0.493 0.0977 453 1 0 1.1 0.383 2.95 PRS_PLINK_0.000251188643150958 371.21 Allergic conjunctivitis Both 1 15 7 sense organs darkseagreen4 15, 1 4, 1 4, 0 3, 0 4, 0 0.0166 1.24 0.989 0.005 1.02 0.0999 13.3 -1.87 11.4 0.87 0.061 0.154 0.105 0.128 -0.155 533000 1 0 0.857 0.757 1.17 0.353 3650000 1 0 1.42 0.673 65.1 PRS_PLINK_0.000251188643150958 371.3 Inflammation of eyelids Both 8 25 7 sense organs darkseagreen4 25, 8 7, 0 6, 2 6, 3 6, 3 0.281 0.495 0.571 0.244 1.32 0.561 3.36 2.49 2.38 0.294 0.532 12.1 0.235 1620 0.305 2.26 0.893 0.049 1.36 0.0039 4910 2.04 2.53 0.421 0.376 7.65 0.0427 1690 PRS_PLINK_0.000251188643150958 372 Disorders of conjunctiva Both 4 13 7 sense organs darkseagreen4 13, 4 3, 0 3, 1 3, 1 3, 2 0.115 0.763 0.88 0.056 1.12 0.234 4.23 -0.112 25500000 1 0 0.894 0.02 18.4 -0.0117 138 1 0 0.988 0.0965 2.4 0.0644 409 1 0 1.07 0.0548 16 PRS_PLINK_0.000251188643150958 374 Other disorders of eyelids Both 9 22 7 sense organs darkseagreen4 22, 9 6, 0 5, 2 5, 3 6, 4 0.0546 0.587 0.926 0.033 1.06 0.394 3.5 1.41 3.47 0.684 0.165 4.1 0.000675 5330 1.8 1.9 0.343 0.465 6.04 0.297 1140 1.81 3.69 0.625 0.204 6.08 0.0248 127000 PRS_PLINK_0.000251188643150958 374.1 Ectropion or entropion Both 1 5 7 sense organs darkseagreen4 5, 1 2, 0 1, 1 1, 0 1, 0 0.119 3210 1 0 1.13 0.136 4.88 0.202 5680 1 0 1.22 0.327 1.48 PRS_PLINK_0.000251188643150958 374.2 Lagophthalmos Both 1 3 7 sense organs darkseagreen4 3, 1 1, 1 1, 0 1, 0 1, 1 13.5 37800 1 0 718000 1.27e-11 3.64e+35 -0.166 6190 1 0 0.847 0.722 2.48 -0.252 5900 1 0 0.777 0.609 4.74 PRS_PLINK_0.000251188643150958 374.3 Ptosis of eyelid Both 2 7 7 sense organs darkseagreen4 7, 2 2, 0 2, 0 1, 1 2, 1 -0.255 65.5 0.997 0.001 0.775 1.26 0.88 -0.0906 2340 1 0 0.913 0.0879 8.43 -0.0123 645 1 0 0.988 0.636 1.51 PRS_PLINK_0.000251188643150958 374.6 Dermatochalasis Both 1 9 7 sense organs darkseagreen4 9, 1 3, 0 2, 0 2, 1 2, 0 0.0107 5.3 0.998 0.001 1.01 0.459 9.24 0.0192 3480 1 0 1.02 0.684 6.05 PRS_PLINK_0.000251188643150958 375 Disorders of lacrimal system Both 12 25 7 sense organs darkseagreen4 25, 12 7, 1 6, 3 6, 4 6, 4 0.829 0.775 0.284 0.546 2.29 0.552 13.3 -0.699 2.01 0.728 0.138 0.497 9.52e-06 16 0.207 1.47 0.888 0.051 1.23 0.105 18.2 1.19 1.84 0.519 0.285 3.27 0.00631 3120 PRS_PLINK_0.000251188643150958 375.1 Dry eyes Both 14 24 7 sense organs darkseagreen4 24, 14 6, 2 6, 6 6, 2 6, 4 0.0217 0.602 0.971 0.013 1.02 0.333 3.11 -0.103 1.73 0.953 0.021 0.902 0.023 15.8 -0.524 1.91 0.783 0.106 0.592 0.00678 149 -0.121 1.42 0.932 0.03 0.886 0.0437 5.44 PRS_PLINK_0.000251188643150958 375.2 Epiphora Both 1 7 7 sense organs darkseagreen4 7, 1 2, 0 2, 0 1, 1 2, 0 -1.75 484 0.997 0.001 0.174 7.37e-06 15800 -0.011 40.4 1 0 0.989 0.94 1.39 PRS_PLINK_0.000251188643150958 376 Disorders of the orbit Both 1 4 7 sense organs darkseagreen4 4, 1 1, 0 1, 0 1, 0 1, 1 -0.74 325 0.998 0.001 0.477 1.02e-06 10500000 0.0134 34 1 0 1.01 0.916 1.07 PRS_PLINK_0.000251188643150958 377 Disorders of optic nerve and visual pathways Both 3 10 7 sense organs darkseagreen4 10, 3 3, 1 2, 1 2, 1 3, 0 -0.819 1.84 0.655 0.184 0.441 0.00872 7.13 -0.00232 9.47 1 0 0.998 0.735 1.21 0.195 1260 1 0 1.22 0.404 20.2 0.084 812 1 0 1.09 0.855 1.78 PRS_PLINK_0.000251188643150958 377.1 Optic atrophy Both 2 3 7 sense organs darkseagreen4 3, 2 1, 1 1, 0 1, 1 1, 1 -1.15 21700 1 0 0.316 7.54e-12 5.56e+10 -0.00664 178 1 0 0.993 0.977 1.1 -15.8 63100 1 0 1.39e-07 1.4e-20 24700000 PRS_PLINK_0.000251188643150958 377.3 Optic neuritis/neuropathy Both 2 5 7 sense organs darkseagreen4 5, 2 2, 1 1, 0 1, 0 1, 1 -0.0435 802 1 0 0.957 0.275 1.51 0.00677 41 1 0 1.01 0.848 1.27 -3.21 5040 0.999 0 0.0402 1.49e-16 3.4e+12 14.5 1.93e+08 1 0 2050000 44100 3.2e+28 PRS_PLINK_0.000251188643150958 378 Strabismus and other disorders of binocular eye movements Both 6 13 7 sense organs darkseagreen4 13, 6 4, 1 3, 1 3, 2 3, 2 0.325 0.993 0.743 0.129 1.38 0.272 7.89 -0.558 8.64 0.949 0.023 0.572 0.545 0.599 -1.03 4.06 0.801 0.097 0.358 0.297 133 0.991 7800000 1 0 2.69 0.423 15.2 PRS_PLINK_0.000251188643150958 378.1 Strabismus (not specified as paralytic) Both 5 11 7 sense organs darkseagreen4 11, 5 3, 1 3, 1 2, 3 3, 0 -1.78 1.88 0.344 0.464 0.169 1.58e-05 2.46 0.197 249 0.999 0 1.22 0.839 2.55 -0.151 32.8 0.996 0.002 0.86 0.677 1.04 -0.643 2550 1 0 0.525 1.68e-05 47700 PRS_PLINK_0.000251188643150958 378.2 Nystagmus and other irregular eye movements Both 1 3 7 sense organs darkseagreen4 3, 1 1, 0 1, 0 0, 1 1, 0 -0.218 3710 1 0 0.804 0.242 1.78 -0.0102 79.1 1 0 0.99 0.768 5.66 PRS_PLINK_0.000251188643150958 378.5 Paralytic strabismus Both 1 3 7 sense organs darkseagreen4 3, 1 1, 0 1, 0 0, 1 1, 0 -0.18 3780 1 0 0.835 0.756 1.82 -0.00603 393 1 0 0.994 0.943 1.06 PRS_PLINK_0.000251188643150958 379 Other disorders of eye Both 19 26 7 sense organs darkseagreen4 26, 19 7, 3 6, 2 6, 6 7, 8 0.627 0.481 0.192 0.716 1.87 0.833 5.39 0.171 1.41 0.903 0.044 1.19 0.0316 17.7 -0.0486 1.27 0.97 0.013 0.953 0.101 11.5 1.85 1.67 0.268 0.571 6.37 0.415 28500 PRS_PLINK_0.000251188643150958 379.1 Scleritis and episcleritis Both 0 3 7 sense organs darkseagreen4 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 379.2 Disorders of vitreous body Both 16 16 7 sense organs darkseagreen4 16, 16 4, 4 4, 0 4, 4 4, 8 0.575 0.532 0.279 0.554 1.78 0.754 5.73 -3 4.08 0.462 0.335 0.0499 8.3e-06 10.8 -0.845 1.61 0.6 0.222 0.429 0.348 4.81 4.37 3.26 0.18 0.746 79.1 0.294 118000 PRS_PLINK_0.000251188643150958 379.3 Aphakia and other disorders of lens Both 0 5 7 sense organs darkseagreen4 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 379.4 Anomalies of pupillary function Both 1 2 7 sense organs darkseagreen4 2, 1 1, 1 1, 0 1, 1 1, 0 -0.00428 517 1 0 0.996 0.806 1.11 0.000835 51.7 1 0 1 0.988 1.01 PRS_PLINK_0.000251188643150958 379.5 Disorders of iris and ciliary body Both 0 3 7 sense organs darkseagreen4 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 379.9 Pain, swelling or discharge of eye Both 6 18 7 sense organs darkseagreen4 18, 6 5, 0 4, 1 4, 3 5, 2 0.91 1.01 0.369 0.433 2.49 0.515 34.6 0.407 3.46 0.906 0.043 1.5 0.00851 292 0.264 1.65 0.872 0.059 1.3 1.2 1.65 2.23 17.7 0.899 0.046 9.32 8.08 10.7 PRS_PLINK_0.000251188643150958 380 Disorders of external ear Both 6 22 7 sense organs darkseagreen4 22, 6 6, 1 5, 2 5, 0 6, 3 0.678 0.682 0.32 0.495 1.97 0.655 16.8 1.24 1.8 0.488 0.311 3.47 0.0519 125 -1.5 7.14 0.834 0.079 0.223 0.183 0.276 1.9 1.96 0.334 0.476 6.67 0.156 61200 PRS_PLINK_0.000251188643150958 380.1 Otitis externa Both 2 26 7 sense organs darkseagreen4 26, 2 7, 0 6, 1 6, 1 7, 0 -0.459 0.95 0.629 0.201 0.632 0.00255 3.72 0.624 2.04 0.759 0.12 1.87 0.0521 208 0.822 3.07 0.789 0.103 2.27 0.00177 521 PRS_PLINK_0.000251188643150958 380.4 Impacted cerumen Both 6 28 7 sense organs darkseagreen4 28, 6 7, 1 7, 2 7, 0 7, 3 0.632 0.655 0.334 0.476 1.88 0.635 13.9 1.08 1.69 0.522 0.282 2.95 0.138 66.4 0.0969 6.96 0.989 0.005 1.1 1.37e-05 1040000 2.1 2.32 0.365 0.438 8.16 0.0177 109000 PRS_PLINK_0.000251188643150958 381 Otitis media and Eustachian tube disorders Both 7 50 7 sense organs darkseagreen4 50, 7 12, 2 12, 2 12, 2 13, 1 -0.374 0.47 0.426 0.371 0.688 0.218 1.64 1.36 1.42 0.34 0.469 3.88 0.249 34200 1.09 1.64 0.504 0.297 2.99 0.0671 252 -0.462 1.17 0.694 0.159 0.63 0.012 9.92 PRS_PLINK_0.000251188643150958 381.1 Otitis media Both 5 45 7 sense organs darkseagreen4 45, 5 11, 1 11, 1 11, 2 11, 1 -0.154 0.478 0.748 0.126 0.857 0.248 2.23 0.741 1.5 0.62 0.207 2.1 0.125 989 0.219 1.35 0.871 0.06 1.24 0.028 20.3 -0.245 1.47 0.868 0.062 0.783 0.00466 947 PRS_PLINK_0.000251188643150958 381.11 Suppurative and unspecified otitis media Both 4 37 7 sense organs darkseagreen4 37, 4 9, 0 9, 1 9, 2 9, 1 0.041 0.515 0.936 0.029 1.04 0.254 2.91 0.238 1.87 0.899 0.046 1.27 0.00904 129 1.47 1.66 0.376 0.425 4.36 0.23 9900 0.0339 1.54 0.982 0.008 1.03 0.0121 48.1 PRS_PLINK_0.000251188643150958 381.2 Eustachian tube disorders Both 4 31 7 sense organs darkseagreen4 31, 4 7, 2 8, 2 7, 0 8, 0 -1.47 0.929 0.114 0.944 0.23 0.0019 1.39 0.064 1.88 0.973 0.012 1.07 0.00809 570 -0.482 1.86 0.795 0.099 0.618 0.0112 124 0.278 2.01 0.89 0.051 1.32 0.0116 404 PRS_PLINK_0.000251188643150958 381.3 Mastoiditis & related conditions Both 0 5 7 sense organs darkseagreen4 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 381.9 Otorrhea Both 0 5 7 sense organs darkseagreen4 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 382 Otalgia Both 4 29 7 sense organs darkseagreen4 29, 4 7, 0 7, 1 7, 2 7, 1 -0.726 0.89 0.415 0.382 0.484 0.00083 6.64 -0.0821 1.79 0.963 0.016 0.921 0.014 66.1 0.314 1.93 0.87 0.06 1.37 0.00708 164 -0.118 2.19 0.957 0.019 0.889 0.000131 1080 PRS_PLINK_0.000251188643150958 383 Otosclerosis Both 0 4 7 sense organs darkseagreen4 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 384 Other disorders of tympanic membrane Both 1 5 7 sense organs darkseagreen4 5, 1 2, 1 1, 0 1, 0 1, 0 -0.764 5840 1 0 0.466 0.00108 64.5 -0.00497 481 1 0 0.995 0.75 1.25 -0.098 8560 1 0 0.907 0.827 21.9 -0.0993 4480 1 0 0.905 0.0467 12.5 PRS_PLINK_0.000251188643150958 384.1 Myringitis Both 0 2 7 sense organs darkseagreen4 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 384.4 Perforation of tympanic membrane Both 1 1 7 sense organs darkseagreen4 1, 1 0.00405 68.3 1 0 1 0.95 1.08 PRS_PLINK_0.000251188643150958 385 Other disorders of middle ear and mastoid Both 0 6 7 sense organs darkseagreen4 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 385.3 Cholesteatoma Both 0 4 7 sense organs darkseagreen4 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 385.5 Tympanosclerosis and middle ear disease related to otitis media Both 0 3 7 sense organs darkseagreen4 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 386 Vertiginous syndromes and other disorders of vestibular system Both 4 23 7 sense organs darkseagreen4 23, 4 6, 1 6, 1 5, 1 6, 1 -0.072 0.646 0.911 0.04 0.931 0.229 3.8 -1.07 3.32 0.747 0.127 0.343 8.95e-09 338 -0.976 2.71 0.719 0.143 0.377 0.00225 29.2 0.845 5.04 0.867 0.062 2.33 0.000832 2450000 PRS_PLINK_0.000251188643150958 386.1 Meniere's disease Both 0 2 7 sense organs darkseagreen4 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 386.2 Peripheral or central vertigo Both 4 17 7 sense organs darkseagreen4 17, 4 4, 1 4, 0 4, 2 4, 1 -0.584 0.935 0.532 0.274 0.558 0.0277 4.28 -0.549 13.6 0.968 0.014 0.577 0.087 0.624 -1.66 5.57 0.766 0.116 0.19 0.145 0.238 -0.197 54.1 0.997 0.001 0.821 0.0183 39 PRS_PLINK_0.000251188643150958 386.21 Central origin vertigo Both 3 14 7 sense organs darkseagreen4 14, 3 4, 0 3, 0 3, 2 4, 1 0.418 1.09 0.7 0.155 1.52 0.0708 20.8 0.868 1100000 1 0 2.38 0.747 4.25 -0.146 1730000 1 0 0.864 0.117 2.13 PRS_PLINK_0.000251188643150958 386.3 Labyrinthitis Both 3 19 7 sense organs darkseagreen4 19, 3 5, 0 5, 1 4, 1 5, 1 0.931 0.94 0.322 0.492 2.54 0.382 72.3 -0.0645 4.99 0.99 0.005 0.938 0.0196 26.8 -2.91 105 0.978 0.01 0.0544 1.63e-05 0.0531 1.93 5.72 0.736 0.133 6.89 0.002 50000 PRS_PLINK_0.000251188643150958 386.9 Dizziness and giddiness (Light-headedness and vertigo) Both 12 46 7 sense organs darkseagreen4 46, 12 11, 2 11, 5 11, 3 12, 2 -0.3 0.453 0.507 0.295 0.741 0.286 1.75 1.44 1.42 0.311 0.507 4.22 0.365 703 -0.678 1.32 0.607 0.217 0.507 0.0299 5.14 -0.537 1.37 0.695 0.158 0.584 0.0202 7.66 PRS_PLINK_0.000251188643150958 388 Other disorders of ear Both 0 7 7 sense organs darkseagreen4 7, 0 2 2 1 2 PRS_PLINK_0.000251188643150958 389 Hearing loss Both 13 49 7 sense organs darkseagreen4 49, 13 12, 5 12, 3 12, 1 12, 4 -0.39 0.454 0.39 0.408 0.677 0.27 1.68 0.158 1.03 0.878 0.057 1.17 0.137 22.9 -2.34 1.44 0.105 0.979 0.0966 0.000335 1.08 -0.431 1.04 0.677 0.169 0.65 0.0637 4.11 PRS_PLINK_0.000251188643150958 389.1 Sensorineural hearing loss Both 7 26 7 sense organs darkseagreen4 26, 7 7, 1 6, 2 6, 1 7, 3 -0.126 0.808 0.876 0.057 0.882 0.122 6.05 0.676 1.41 0.633 0.199 1.97 0.137 56.6 -1.11 1.93 0.564 0.248 0.328 0.00387 7.23 -0.349 2.24 0.876 0.057 0.706 0.000823 74.7 PRS_PLINK_0.000251188643150958 389.2 Conductive hearing loss Both 1 11 7 sense organs darkseagreen4 11, 1 3, 1 3, 0 2, 0 3, 0 -0.854 3.18 0.788 0.103 0.426 0.0151 9.09 -0.0727 161 1 0 0.93 0.58 1.33 0.196 2130 1 0 1.22 0.267 18.4 0.0462 128 1 0 1.05 0.626 1.43 PRS_PLINK_0.000251188643150958 389.3 Degenerative and vascular disorders of ear Both 0 2 7 sense organs darkseagreen4 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 389.4 Tinnitus Both 5 27 7 sense organs darkseagreen4 27, 5 7, 4 7, 0 6, 1 7, 0 -0.949 0.853 0.266 0.575 0.387 0.051 1.65 -0.586 1.85 0.752 0.124 0.557 0.0189 12.2 -1.13 1.31 0.388 0.411 0.323 0.00314 2.4 -0.907 1.8 0.615 0.211 0.404 0.000835 5.84 PRS_PLINK_0.000251188643150958 389.5 Disorders of acoustic nerve Both 0 1 7 sense organs darkseagreen4 1, 0 PRS_PLINK_0.000251188643150958 394 Rheumatic disease of the heart valves Both 1 8 8 circulatory system red 8, 1 2, 0 2, 1 2, 0 2, 0 -0.159 18.1 0.993 0.003 0.853 0.0355 49.1 -0.0484 1250 1 0 0.953 0.594 1.15 PRS_PLINK_0.000251188643150958 394.1 Mitral valve stenosis and aortic valve stenosis Both 1 1 8 circulatory system red 1, 1 -0.0079 53.4 1 0 0.992 0.78 1.37 PRS_PLINK_0.000251188643150958 394.2 Mitral valve disease Both 0 3 8 circulatory system red 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 394.7 Disease of tricuspid valve Both 0 2 8 circulatory system red 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 395 Heart valve disorders Both 4 31 8 circulatory system red 31, 4 8, 2 8, 1 7, 1 8, 0 -0.662 0.704 0.347 0.46 0.516 0.0929 1.83 1.05 2.09 0.616 0.21 2.85 0.00171 3540 2.4 3.05 0.432 0.364 11 0.0949 53200 0.265 2.51 0.916 0.038 1.3 0.00162 202000 PRS_PLINK_0.000251188643150958 395.1 Nonrheumatic mitral valve disorders Both 2 18 8 circulatory system red 18, 2 5, 1 4, 1 4, 0 5, 0 -0.966 1.25 0.438 0.358 0.381 1.34e-05 3 -0.923 17.7 0.958 0.018 0.397 0.355 0.457 1.06 4.76 0.824 0.084 2.88 0.000938 2460 5.19e-12 11.6 1 0 1 0.0305 35.5 PRS_PLINK_0.000251188643150958 395.2 Nonrheumatic aortic valve disorders Both 2 14 8 circulatory system red 14, 2 4, 1 3, 0 3, 1 4, 0 -0.0945 0.975 0.923 0.035 0.91 0.14 18.3 -1.84 300 0.995 0.002 0.159 0.0516 0.122 0.403 1620 1 0 1.5 1.53 6.21 -0.206 51.5 0.997 0.001 0.814 0.00727 2200 PRS_PLINK_0.000251188643150958 395.3 Nonrheumatic tricuspid valve disorders Both 0 4 8 circulatory system red 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 395.4 Nonrheumatic pulmonary valve disorders Both 0 2 8 circulatory system red 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 395.6 Heart valve replaced Both 0 9 8 circulatory system red 9, 0 3 2 2 2 PRS_PLINK_0.000251188643150958 396 Abnormal heart sounds Both 4 45 8 circulatory system red 45, 4 12, 1 11, 2 11, 0 11, 1 -0.332 0.563 0.556 0.255 0.718 0.2 2.39 1.08 1.45 0.458 0.339 2.94 0.137 903 -0.123 1.51 0.935 0.029 0.885 0.00874 196 0.632 1.45 0.663 0.179 1.88 0.00996 331000 PRS_PLINK_0.000251188643150958 401 Hypertension Both 29 35 8 circulatory system red 35, 29 8, 5 9, 6 8, 10 9, 8 0.354 0.327 0.278 0.557 1.43 0.771 2.67 0.293 1.2 0.806 0.093 1.34 0.147 17.7 0.336 0.983 0.732 0.135 1.4 0.244 9.62 -0.117 1.07 0.913 0.04 0.889 0.11 6.02 PRS_PLINK_0.000251188643150958 401.1 Essential hypertension Both 29 35 8 circulatory system red 35, 29 8, 5 9, 6 8, 10 9, 8 0.354 0.327 0.278 0.557 1.43 0.771 2.67 0.293 1.2 0.806 0.093 1.34 0.147 17.7 0.336 0.983 0.732 0.135 1.4 0.244 9.62 -0.117 1.07 0.913 0.04 0.889 0.11 6.02 PRS_PLINK_0.000251188643150958 401.2 Hypertensive heart and/or renal disease Both 1 19 8 circulatory system red 19, 1 5, 0 5, 0 4, 1 5, 0 0.238 1.03 0.818 0.087 1.27 0.0727 35.8 2.01 3.71 0.588 0.231 7.47 0.0395 3010 PRS_PLINK_0.000251188643150958 401.21 Hypertensive heart disease Both 0 7 8 circulatory system red 7, 0 2 2 1 2 PRS_PLINK_0.000251188643150958 401.22 Hypertensive chronic kidney disease Both 1 18 8 circulatory system red 18, 1 5, 0 4, 0 4, 1 5, 0 0.136 0.996 0.892 0.05 1.15 0.0388 15.6 1.93 3.7 0.602 0.22 6.89 0.0327 2540 PRS_PLINK_0.000251188643150958 401.3 Other hypertensive complications Both 5 23 8 circulatory system red 23, 5 5, 1 6, 1 5, 2 6, 1 0.107 0.813 0.895 0.048 1.11 0.243 27.8 0.42 1.84 0.819 0.087 1.52 0.0808 30.3 0.618 2.08 0.766 0.116 1.86 0.0466 204 -0.426 8.66 0.961 0.017 0.653 2.17e-06 183000 PRS_PLINK_0.000251188643150958 411 Ischemic Heart Disease Both 13 34 8 circulatory system red 34, 13 9, 4 8, 3 8, 3 9, 3 -0.349 0.427 0.414 0.383 0.705 0.301 1.52 -1.4 1.4 0.318 0.497 0.248 0.000656 2.42 0.0255 1.32 0.985 0.007 1.03 0.0843 11.4 -1.84 1.63 0.257 0.59 0.158 0.00148 5.13 PRS_PLINK_0.000251188643150958 411.1 Unstable angina (intermediate coronary syndrome) Both 0 12 8 circulatory system red 12, 0 3 3 3 3 PRS_PLINK_0.000251188643150958 411.2 Myocardial infarction Both 5 25 8 circulatory system red 25, 5 7, 2 6, 0 6, 0 6, 3 -0.532 0.641 0.407 0.391 0.587 0.0633 1.75 -0.954 1.96 0.626 0.204 0.385 0.00604 7.47 0.561 2.41 0.816 0.088 1.75 0.0228 2190 -1.19 1.71 0.485 0.314 0.303 0.00177 5.02 PRS_PLINK_0.000251188643150958 411.3 Angina pectoris Both 3 22 8 circulatory system red 22, 3 6, 1 5, 1 5, 1 6, 0 -0.46 0.739 0.534 0.272 0.632 0.0779 10.7 3.13 3.12 0.317 0.499 22.8 0.16 17000 -1.87 4.61 0.685 0.164 0.155 1.75e-07 474 -1.39 5.02 0.781 0.107 0.249 6.49e-06 151000 PRS_PLINK_0.000251188643150958 411.4 Coronary atherosclerosis Both 7 31 8 circulatory system red 31, 7 8, 1 8, 2 7, 1 8, 3 0.389 0.573 0.497 0.303 1.48 0.487 5.6 0.375 1.49 0.801 0.096 1.45 0.0528 159 0.972 2.03 0.632 0.199 2.64 0.0327 1220 1.03 1.94 0.595 0.226 2.81 0.0332 78300 PRS_PLINK_0.000251188643150958 411.41 Aneurysm and dissection of heart Both 0 3 8 circulatory system red 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 411.8 Other chronic ischemic heart disease, unspecified Both 7 30 8 circulatory system red 30, 7 8, 1 7, 3 7, 1 8, 2 -0.464 0.534 0.385 0.415 0.629 0.2 1.59 0.953 1.69 0.572 0.242 2.59 0.134 171000 1.01 1.73 0.557 0.254 2.75 0.134 434 -0.0598 1.72 0.972 0.012 0.942 0.000851 175 PRS_PLINK_0.000251188643150958 411.9 Other acute and subacute forms of ischemic heart disease Both 0 4 8 circulatory system red 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 414 Other forms of chronic heart disease Both 4 26 8 circulatory system red 26, 4 7, 0 6, 2 6, 0 7, 2 -0.459 0.729 0.529 0.277 0.632 0.0285 2.42 -0.443 1.96 0.821 0.086 0.642 0.0213 20.4 -0.633 2.7 0.814 0.089 0.531 4.06e-05 583 PRS_PLINK_0.000251188643150958 414.2 ASCVD Both 1 10 8 circulatory system red 10, 1 3, 0 2, 1 2, 0 3, 0 0.113 1.94 0.954 0.021 1.12 0.0102 18.4 -0.159 2440 1 0 0.853 0.744 1.77 PRS_PLINK_0.000251188643150958 415 Pulmonary heart disease Both 4 33 8 circulatory system red 33, 4 9, 1 8, 1 8, 1 8, 1 0.382 0.687 0.578 0.238 1.47 0.373 17.3 0.69 1.32 0.601 0.221 1.99 0.203 72.4 0.625 1.76 0.722 0.142 1.87 0.0514 596 -1.54 2.76 0.576 0.24 0.214 1.49e-05 16.3 PRS_PLINK_0.000251188643150958 415.1 Acute pulmonary heart disease Both 1 19 8 circulatory system red 19, 1 5, 1 5, 0 4, 0 5, 0 -0.326 0.936 0.728 0.138 0.722 0.0546 5.74 0.0428 4.36 0.992 0.003 1.04 0.923 1.14 -0.601 4.96 0.904 0.044 0.548 0.00612 38.5 0.524 3.71 0.888 0.052 1.69 0.00638 868 PRS_PLINK_0.000251188643150958 415.11 Pulmonary embolism and infarction, acute Both 1 19 8 circulatory system red 19, 1 5, 1 5, 0 4, 0 5, 0 -0.326 0.936 0.728 0.138 0.722 0.0546 5.74 0.0428 4.36 0.992 0.003 1.04 0.923 1.14 -0.601 4.96 0.904 0.044 0.548 0.00612 38.5 0.524 3.71 0.888 0.052 1.69 0.00638 868 PRS_PLINK_0.000251188643150958 415.2 Chronic pulmonary heart disease Both 4 20 8 circulatory system red 20, 4 5, 2 5, 0 5, 1 5, 1 -0.292 0.702 0.678 0.169 0.747 0.0961 4.46 0.69 6.44 0.915 0.039 1.99 1.5 2.44 1.85 3.58 0.605 0.218 6.37 0.0589 2950 -0.00142 7.68 1 0 0.999 0.821 1.08 PRS_PLINK_0.000251188643150958 415.21 Primary pulmonary hypertension Both 3 9 8 circulatory system red 9, 3 3, 0 2, 0 2, 2 2, 1 0.423 1.68 0.801 0.096 1.53 0.113 48.4 0.421 5140 1 0 1.52 0.734 2.83 0.00314 29.9 1 0 1 0.938 1.13 PRS_PLINK_0.000251188643150958 416 Cardiomegaly Both 1 15 8 circulatory system red 15, 1 4, 0 4, 0 3, 1 4, 0 -0.0305 1.52 0.984 0.007 0.97 0.0341 167 -0.18 40800000 1 0 0.835 0.02 39.1 PRS_PLINK_0.000251188643150958 418 Nonspecific chest pain Both 28 35 8 circulatory system red 35, 28 8, 5 9, 12 8, 4 9, 7 0.171 0.338 0.614 0.212 1.19 0.628 2.25 0.775 0.888 0.383 0.417 2.17 0.461 11.7 -0.261 1.24 0.833 0.08 0.77 0.0792 7.13 0.298 1.02 0.77 0.113 1.35 0.235 8.57 PRS_PLINK_0.000251188643150958 418.1 Precordial pain Both 4 12 8 circulatory system red 12, 4 3, 0 3, 0 3, 0 3, 4 0.21 1.15 0.855 0.068 1.23 0.144 35.5 1.29 1250 0.999 0 3.64 28.7 44.3 PRS_PLINK_0.000251188643150958 420 Carditis Both 1 16 8 circulatory system red 16, 1 4, 0 4, 1 4, 0 4, 0 0.171 0.9 0.849 0.071 1.19 0.203 21.4 -0.224 2800 1 0 0.799 0.273 2.11 PRS_PLINK_0.000251188643150958 420.2 Pericarditis Both 1 7 8 circulatory system red 7, 1 2, 0 2, 0 1, 1 2, 0 0.339 130 0.998 0.001 1.4 0.96 1.82 -0.0418 3540 1 0 0.959 0.396 2.13 PRS_PLINK_0.000251188643150958 420.21 Acute pericarditis Both 1 3 8 circulatory system red 3, 1 1, 0 1, 0 0, 1 1, 0 0.211 13200 1 0 1.23 0.0945 30.5 -0.0127 71.8 1 0 0.987 0.848 1.17 PRS_PLINK_0.000251188643150958 420.22 Chronic pericarditis Both 1 0 8 circulatory system red 0, 1 PRS_PLINK_0.000251188643150958 420.3 Endocarditis Both 0 9 8 circulatory system red 9, 0 3 2 2 2 PRS_PLINK_0.000251188643150958 425 Cardiomyopathy Both 3 19 8 circulatory system red 19, 3 5, 1 5, 0 4, 1 5, 1 -0.545 0.914 0.551 0.259 0.58 0.0253 6.67 0.136 3.34 0.967 0.014 1.15 0.0135 1.26 -1.28 11.6 0.913 0.04 0.279 0.253 0.309 -0.246 2.33 0.916 0.038 0.782 0.011 28.7 PRS_PLINK_0.000251188643150958 425.1 Primary/intrinsic cardiomyopathies Both 3 19 8 circulatory system red 19, 3 5, 1 5, 0 4, 1 5, 1 -0.545 0.914 0.551 0.259 0.58 0.0253 6.67 0.136 3.34 0.967 0.014 1.15 0.0135 1.26 -1.28 11.6 0.913 0.04 0.279 0.253 0.309 -0.246 2.33 0.916 0.038 0.782 0.011 28.7 PRS_PLINK_0.000251188643150958 425.11 Hypertrophic obstructive cardiomyopathy Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_0.000251188643150958 425.12 Other hypertrophic cardiomyopathy Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_0.000251188643150958 425.2 Secondary/extrinsic cardiomyopathies Both 0 2 8 circulatory system red 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 425.8 Other cardiomyopathy Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_0.000251188643150958 426 Cardiac conduction disorders Both 17 33 8 circulatory system red 33, 17 8, 4 8, 6 8, 4 8, 3 -0.00499 0.339 0.988 0.005 0.995 0.521 1.85 0.271 0.896 0.763 0.118 1.31 0.285 6.49 0.256 1.16 0.825 0.084 1.29 0.182 10.1 -0.645 1.18 0.584 0.234 0.525 0.0501 3.92 PRS_PLINK_0.000251188643150958 426.2 Atrioventricular [AV] block Both 0 12 8 circulatory system red 12, 0 3 3 3 3 PRS_PLINK_0.000251188643150958 426.21 First degree AV block Both 0 10 8 circulatory system red 10, 0 3 2 2 3 PRS_PLINK_0.000251188643150958 426.23 Second degree AV block Both 0 2 8 circulatory system red 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 426.24 Atrioventricular block, complete Both 0 3 8 circulatory system red 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 426.25 Other heart block Both 0 2 8 circulatory system red 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 426.3 Bundle branch block Both 2 16 8 circulatory system red 16, 2 4, 0 4, 0 4, 2 4, 0 0.368 1.07 0.732 0.135 1.44 0.0478 93.1 1.81 27.3 0.947 0.024 6.12 5.55 6.75 PRS_PLINK_0.000251188643150958 426.31 Right bundle branch block Both 2 7 8 circulatory system red 7, 2 2, 0 2, 0 1, 1 2, 1 -0.0471 1620 1 0 0.954 0.902 1.63 0.00421 422 1 0 1 0.863 1.19 -0.000352 60.4 1 0 1 0.539 1.43 PRS_PLINK_0.000251188643150958 426.32 Left bundle branch block Both 0 11 8 circulatory system red 11, 0 3 3 2 3 PRS_PLINK_0.000251188643150958 426.4 Anomalous atrioventricular excitation Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_0.000251188643150958 426.7 Abnormal electrocardiogram [ECG] [EKG] Both 16 31 8 circulatory system red 31, 16 7, 5 8, 5 7, 2 8, 4 0.00624 0.395 0.987 0.006 1.01 0.492 2.11 -0.183 1.02 0.858 0.066 0.833 0.142 4.8 -0.933 1.42 0.51 0.292 0.393 0.0239 3.79 -0.395 1.21 0.745 0.128 0.674 0.0586 5.1 PRS_PLINK_0.000251188643150958 426.8 Other cardiac conduction disorders Both 0 5 8 circulatory system red 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 426.9 Cardiac pacemaker/device in situ Both 1 11 8 circulatory system red 11, 1 3, 0 3, 0 2, 1 3, 0 0.232 1.06 0.826 0.083 1.26 0.204 14.9 -0.0994 1820 1 0 0.905 0.426 1.64 PRS_PLINK_0.000251188643150958 426.91 Cardiac pacemaker in situ Both 0 4 8 circulatory system red 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 426.92 Cardiac defibrillator in situ Both 0 6 8 circulatory system red 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 427 Cardiac dysrhythmias Both 25 33 8 circulatory system red 33, 25 8, 7 8, 5 8, 5 8, 8 -0.12 0.328 0.715 0.146 0.887 0.475 1.6 -0.0872 1.09 0.936 0.029 0.917 0.12 6.15 -0.259 1.1 0.813 0.09 0.772 0.0918 5.52 -0.362 1.04 0.727 0.138 0.696 0.0833 4.41 PRS_PLINK_0.000251188643150958 427.1 Paroxysmal tachycardia, unspecified Both 4 22 8 circulatory system red 22, 4 6, 2 5, 1 5, 1 6, 0 -0.353 0.614 0.566 0.247 0.703 0.0931 2 -0.126 2.87 0.965 0.015 0.881 1.8e-05 58.6 0.244 2.4 0.919 0.037 1.28 0.0119 1660 -0.866 2.54 0.733 0.135 0.421 7.58e-05 69.1 PRS_PLINK_0.000251188643150958 427.11 Paroxysmal supraventricular tachycardia Both 2 14 8 circulatory system red 14, 2 4, 0 3, 2 3, 0 4, 0 -0.146 1.14 0.898 0.047 0.864 0.0646 276 -0.888 35.8 0.98 0.009 0.412 0.00187 89.8 PRS_PLINK_0.000251188643150958 427.12 Paroxysmal ventricular tachycardia Both 2 10 8 circulatory system red 10, 2 3, 1 2, 0 2, 0 3, 1 -0.256 1.2 0.832 0.08 0.774 0.0506 5.91 -0.133 8480000 1 0 0.875 0.12 25.1 0.176 598 1 0 1.19 0.68 3.69 -0.447 8.09 0.956 0.02 0.639 0.632 1.34 PRS_PLINK_0.000251188643150958 427.2 Atrial fibrillation and flutter Both 4 22 8 circulatory system red 22, 4 6, 2 5, 1 5, 1 6, 0 0.574 0.833 0.491 0.309 1.78 0.275 16.3 0.58 2.92 0.843 0.074 1.79 0.00555 154 -0.16 5.32 0.976 0.011 0.852 3.68e-08 3770 -0.656 2.37 0.782 0.107 0.519 0.00197 143 PRS_PLINK_0.000251188643150958 427.21 Atrial fibrillation Both 4 20 8 circulatory system red 20, 4 5, 2 5, 1 5, 0 5, 1 0.479 1.01 0.636 0.197 1.61 0.249 20.3 0.508 2.93 0.862 0.064 1.66 0.00512 129 0.0892 5.68 0.987 0.005 1.09 0.797 1.23 -0.506 3 0.866 0.063 0.603 0.00122 3760 PRS_PLINK_0.000251188643150958 427.22 Atrial flutter Both 1 11 8 circulatory system red 11, 1 3, 1 3, 0 2, 0 3, 0 0.102 1.04 0.922 0.035 1.11 0.204 6.34 0.0285 1920 1 0 1.03 0.353 3.2 0.0218 4310 1 0 1.02 0.46 2.34 -1.4 8.9 0.875 0.058 0.248 0.232 0.257 PRS_PLINK_0.000251188643150958 427.3 Other specified cardiac dysrhythmias Both 12 33 8 circulatory system red 33, 12 8, 3 8, 3 8, 3 8, 3 -0.263 0.455 0.563 0.249 0.769 0.26 1.75 -1.1 1.48 0.458 0.339 0.334 0.0103 3.93 0.976 1.54 0.527 0.278 2.65 0.169 514 -1.22 1.57 0.44 0.357 0.297 3.42e-14 3.82 PRS_PLINK_0.000251188643150958 427.4 Cardiac arrest and ventricular fibrillation Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_0.000251188643150958 427.41 Ventricular fibrillation and flutter Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_0.000251188643150958 427.42 Cardiac arrest Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_0.000251188643150958 427.5 Arrhythmia (cardiac) NOS Both 5 32 8 circulatory system red 32, 5 7, 2 8, 1 8, 1 8, 1 0.0136 0.536 0.98 0.009 1.01 0.252 4.72 -2.17 1.95 0.265 0.576 0.114 0.00133 2.55 -1.31 1.9 0.49 0.31 0.269 0.000596 7.18 -0.769 1.75 0.661 0.18 0.464 0.00442 12.1 PRS_PLINK_0.000251188643150958 427.6 Premature beats Both 4 19 8 circulatory system red 19, 4 5, 1 5, 0 4, 3 5, 0 -0.276 1.1 0.803 0.095 0.759 0.0127 28.7 -1.2 5.86 0.837 0.077 0.301 4.92e-05 5410 -0.52 4.63 0.911 0.041 0.594 0.000211 3160 0.272 3.88 0.944 0.025 1.31 0.004 189 PRS_PLINK_0.000251188643150958 427.61 Supraventricular premature beats Both 1 8 8 circulatory system red 8, 1 2, 0 2, 0 2, 1 2, 0 0.0162 468 1 0 1.02 0.729 1.95 -0.202 7410 1 0 0.817 0.587 3.33 PRS_PLINK_0.000251188643150958 427.7 Tachycardia NOS Both 5 33 8 circulatory system red 33, 5 8, 0 8, 2 8, 1 8, 2 0.0254 0.465 0.956 0.019 1.03 0.386 2.5 1.6 1.54 0.298 0.525 4.94 0.426 951 0.483 1.88 0.797 0.098 1.62 0.011 1920 0.963 1.59 0.544 0.264 2.62 0.168 94.5 PRS_PLINK_0.000251188643150958 427.8 Sinoatrial node dysfunction (Bradycardia) Both 0 6 8 circulatory system red 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 427.9 Palpitations Both 9 31 8 circulatory system red 31, 9 7, 3 8, 1 7, 2 8, 3 -0.0141 0.469 0.976 0.011 0.986 0.367 2.67 0.514 1.63 0.753 0.123 1.67 0.0866 79 -0.144 1.34 0.914 0.039 0.866 0.0646 8.36 -0.296 1.46 0.839 0.076 0.744 0.017 42.7 PRS_PLINK_0.000251188643150958 428 Congestive heart failure; nonhypertensive Both 3 20 8 circulatory system red 20, 3 5, 1 5, 0 5, 1 5, 1 -0.746 1 0.457 0.34 0.474 0.00339 3.63 0.416 3.41 0.903 0.044 1.52 0.000198 261 -0.755 3.04 0.804 0.095 0.47 0.00374 61 -0.533 3.51 0.879 0.056 0.587 6.7e-06 21600 PRS_PLINK_0.000251188643150958 428.1 Congestive heart failure (CHF) NOS Both 2 18 8 circulatory system red 18, 2 5, 1 4, 0 4, 0 5, 1 -0.637 0.946 0.501 0.3 0.529 0.00744 6.93 -1.5 6.18 0.808 0.093 0.222 8.76e-06 1160 -0.754 1.96 0.701 0.154 0.471 0.0198 7.34 -0.965 2.56 0.706 0.151 0.381 0.00031 100 PRS_PLINK_0.000251188643150958 428.2 Heart failure NOS Both 3 18 8 circulatory system red 18, 3 5, 1 4, 0 4, 1 5, 1 -1.12 1.25 0.372 0.43 0.326 0.00422 18.7 -1.5 6.18 0.808 0.093 0.222 8.76e-06 1160 -0.895 2.37 0.706 0.151 0.408 0.00931 12.6 -0.965 2.56 0.706 0.151 0.381 0.00031 100 PRS_PLINK_0.000251188643150958 428.3 Heart failure with reduced EF [Systolic or combined heart failure] Both 2 9 8 circulatory system red 9, 2 3, 1 2, 0 2, 0 2, 1 -0.215 1.32 0.871 0.06 0.807 0.0451 6.53 0.057 526 1 0 1.06 0.288 2.64 -0.51 497 0.999 0 0.601 0.0477 0.563 -0.0334 46.9 0.999 0 0.967 0.932 1.07 PRS_PLINK_0.000251188643150958 428.4 Heart failure with preserved EF [Diastolic heart failure] Both 1 11 8 circulatory system red 11, 1 3, 0 3, 0 2, 0 3, 1 -0.0968 1.65 0.953 0.021 0.908 0.031 16.1 0.178 538 1 0 1.19 0.527 2.7 PRS_PLINK_0.000251188643150958 429 Ill-defined descriptions and complications of heart disease Both 28 35 8 circulatory system red 35, 28 8, 4 9, 7 8, 8 9, 9 0.206 0.311 0.507 0.295 1.23 0.691 2.2 0.536 1.15 0.64 0.194 1.71 0.211 46.5 0.175 1.05 0.868 0.062 1.19 0.189 8.15 0.554 1.05 0.598 0.224 1.74 0.281 12.3 PRS_PLINK_0.000251188643150958 429.1 Heart transplant/surgery Both 2 5 8 circulatory system red 5, 2 2, 1 1, 1 1, 0 1, 0 0.0517 1.1e+07 1 0 1.05 0.154 3.13 0.000274 30.5 1 0 1 0.834 1.05 0.0436 338 1 0 1.04 0.262 3.54 0.00912 34.5 1 0 1.01 0.98 1.04 PRS_PLINK_0.000251188643150958 429.2 Abnormal function study of cardiovascular system Both 15 30 8 circulatory system red 30, 15 7, 2 7, 3 7, 5 8, 5 0.396 0.422 0.348 0.458 1.49 0.711 3.36 0.571 1.74 0.743 0.129 1.77 0.0324 136 0.654 1.13 0.564 0.249 1.92 0.296 16 0.879 1.27 0.489 0.31 2.41 0.303 25.8 PRS_PLINK_0.000251188643150958 429.3 Symptoms involving cardiovascular system Both 18 35 8 circulatory system red 35, 18 8, 3 9, 6 8, 3 9, 6 0.0388 0.386 0.92 0.036 1.04 0.47 2.08 0.605 1.17 0.604 0.219 1.83 0.235 28.9 -0.118 1.65 0.943 0.026 0.888 0.00515 93.8 0.521 1.19 0.662 0.179 1.68 0.196 22.4 PRS_PLINK_0.000251188643150958 429.9 Cardiac complications, not elsewhere classified Both 1 2 8 circulatory system red 2, 1 1, 1 1, 0 1, 1 1, 0 -0.0211 28.7 0.999 0 0.979 0.924 1.02 0.0225 30.5 0.999 0 1.02 0.971 1.09 PRS_PLINK_0.000251188643150958 430 Intracranial hemorrhage Both 1 11 8 circulatory system red 11, 1 3, 0 3, 0 2, 1 3, 0 -0.502 2.2 0.819 0.086 0.605 0.00269 34.2 -0.0611 2120 1 0 0.941 0.596 1.4 PRS_PLINK_0.000251188643150958 430.1 Subarachnoid hemorrhage Both 0 4 8 circulatory system red 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 430.2 Intracerebral hemorrhage Both 0 3 8 circulatory system red 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 430.3 Subdural hemorrhage Both 0 3 8 circulatory system red 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 433 Cerebrovascular disease Both 8 35 8 circulatory system red 35, 8 9, 2 9, 2 8, 2 9, 2 -0.128 0.558 0.819 0.087 0.88 0.255 2.49 0.276 1.25 0.824 0.084 1.32 0.155 11.1 -0.993 1.54 0.518 0.285 0.37 0.00135 13.9 0.253 1.69 0.881 0.055 1.29 0.0593 270 PRS_PLINK_0.000251188643150958 433.1 Occlusion and stenosis of precerebral arteries Both 3 15 8 circulatory system red 15, 3 4, 2 4, 1 3, 0 4, 0 -0.477 0.95 0.616 0.211 0.621 0.0304 4.13 -0.638 3.07 0.835 0.078 0.529 0.506 0.557 0.0212 3250 1 0 1.02 0.553 1.93 -6.72 31.9 0.833 0.079 0.00121 0.000738 0.00198 PRS_PLINK_0.000251188643150958 433.11 Occlusion of cerebral arteries, with cerebral infarction Both 1 2 8 circulatory system red 2, 1 1, 0 1, 1 1, 0 1, 1 -0.0149 50.7 1 0 0.985 0.858 1.17 0.00837 37.3 1 0 1.01 0.849 1.06 PRS_PLINK_0.000251188643150958 433.12 Cerebral atherosclerosis Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_0.000251188643150958 433.2 Occlusion of cerebral arteries Both 2 24 8 circulatory system red 24, 2 6, 0 6, 0 6, 1 6, 1 0.244 1.03 0.812 0.09 1.28 0.0563 19.2 0.682 2.08 0.743 0.129 1.98 0.0535 70.3 0.0546 2.26 0.981 0.008 1.06 0.00231 63.6 PRS_PLINK_0.000251188643150958 433.21 Cerebral artery occlusion, with cerebral infarction Both 2 23 8 circulatory system red 23, 2 6, 0 6, 0 5, 1 6, 1 0.234 1.04 0.822 0.085 1.26 0.0611 19.9 0.902 2.49 0.717 0.145 2.46 0.00714 12200 0.0675 2.71 0.98 0.009 1.07 0.00114 169 PRS_PLINK_0.000251188643150958 433.3 Cerebral ischemia Both 5 25 8 circulatory system red 25, 5 7, 0 6, 0 6, 3 6, 2 0.284 0.805 0.724 0.14 1.33 0.118 6.37 1.57 1.61 0.329 0.483 4.83 0.275 201 0.462 2.81 0.869 0.061 1.59 0.0102 1810 PRS_PLINK_0.000251188643150958 433.31 Transient cerebral ischemia Both 4 21 8 circulatory system red 21, 4 6, 0 5, 2 5, 0 5, 2 0.39 0.788 0.62 0.207 1.48 0.112 585 5.61 17.6 0.75 0.125 273 200 380 0.281 3.26 0.931 0.031 1.32 0.0116 1180 PRS_PLINK_0.000251188643150958 433.5 Cerebral aneurysm Both 1 8 8 circulatory system red 8, 1 2, 0 2, 0 2, 0 2, 1 -0.00853 9.08 0.999 0 0.992 0.199 0.864 0.108 4070 1 0 1.11 0.828 1.12 PRS_PLINK_0.000251188643150958 433.6 Acute, but ill-defined cerebrovascular disease Both 0 6 8 circulatory system red 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 433.8 Late effects of cerebrovascular disease Both 1 7 8 circulatory system red 7, 1 2, 0 2, 1 1, 0 2, 0 -0.37 921 1 0 0.691 0.183 4.99 0.12 1650 1 0 1.13 0.0703 3.79 PRS_PLINK_0.000251188643150958 440 Atherosclerosis Both 2 19 8 circulatory system red 19, 2 5, 0 5, 1 4, 0 5, 1 0.775 1.3 0.55 0.259 2.17 0.114 38300 0.726 2.66 0.785 0.105 2.07 1.87 2.22 4.62 14.4 0.749 0.126 101 76.4 135 PRS_PLINK_0.000251188643150958 440.1 Atherosclerosis of renal artery Both 0 2 8 circulatory system red 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 440.2 Atherosclerosis of the extremities Both 2 16 8 circulatory system red 16, 2 4, 0 4, 1 4, 0 4, 1 1.39 1.6 0.382 0.418 4.03 0.0586 252 -1.04 398 0.998 0.001 0.354 0.189 0.368 1.77 48.7 0.971 0.013 5.88 4.9e-06 8730000 PRS_PLINK_0.000251188643150958 440.21 Atherosclerosis of native arteries of the extremities with ulceration or gangrene Both 0 9 8 circulatory system red 9, 0 3 2 2 2 PRS_PLINK_0.000251188643150958 440.22 Atherosclerosis of native arteries of the extremities with intermittent claudication Both 2 11 8 circulatory system red 11, 2 3, 0 3, 0 2, 1 3, 1 0.101 1.72 0.953 0.021 1.11 0.89 1.36 -0.163 4860 1 0 0.85 0.69 2.4 -0.1 1190 1 0 0.905 0.332 1.9 PRS_PLINK_0.000251188643150958 440.9 Atherosclerosis of aorta Both 1 3 8 circulatory system red 3, 1 1, 0 1, 0 1, 1 1, 0 0.0276 859 1 0 1.03 0.85 1.55 0.238 5880 1 0 1.27 0.523 1.67 PRS_PLINK_0.000251188643150958 441 Vascular insufficiency of intestine Both 0 8 8 circulatory system red 8, 0 2 2 2 2 PRS_PLINK_0.000251188643150958 441.1 Acute vascular insufficiency of intestine Both 0 3 8 circulatory system red 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 442 Other aneurysm Both 4 21 8 circulatory system red 21, 4 6, 2 5, 1 5, 1 5, 0 0.36 0.616 0.559 0.252 1.43 0.32 1.53 -0.513 1.86 0.783 0.106 0.598 0.00387 29.6 0.778 3.1 0.802 0.096 2.18 0.00559 9.1e+07 -0.759 4.24 0.858 0.067 0.468 0.000263 1200 PRS_PLINK_0.000251188643150958 442.1 Aortic aneurysm Both 3 13 8 circulatory system red 13, 3 4, 1 3, 1 3, 1 3, 0 0.0611 0.816 0.94 0.027 1.06 0.0934 6.21 -2.15 29.1 0.941 0.026 0.116 0.00659 0.122 0.0277 3.19 0.993 0.003 1.03 1 70.1 -2.06 3380000 1 0 0.127 0.00138 2.31 PRS_PLINK_0.000251188643150958 442.11 Abdominal aortic aneurysm Both 1 4 8 circulatory system red 4, 1 1, 0 1, 0 1, 1 1, 0 1.68 2240 0.999 0 5.34 0.00515 7500 0.00553 41.1 1 0 1.01 0.923 1.09 PRS_PLINK_0.000251188643150958 442.3 Aneurysm of artery of lower extremity Both 0 2 8 circulatory system red 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 442.4 Arterial dissection Both 1 0 8 circulatory system red 0, 1 PRS_PLINK_0.000251188643150958 442.8 Aneurysm of other specified artery Both 0 3 8 circulatory system red 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 443 Peripheral vascular disease Both 3 28 8 circulatory system red 28, 3 7, 0 7, 0 7, 2 7, 1 1.61 1.06 0.127 0.897 5.01 0.572 937 1.29 1.75 0.461 0.336 3.64 0.0854 841 1.61 2.18 0.461 0.337 4.99 0.0711 1070 PRS_PLINK_0.000251188643150958 443.1 Raynaud's syndrome Both 1 7 8 circulatory system red 7, 1 2, 0 2, 1 1, 0 2, 0 -0.0789 363 1 0 0.924 0.598 1.4 -0.00567 56200000 1 0 0.994 0.163 1.65 PRS_PLINK_0.000251188643150958 443.7 Peripheral angiopathy in diseases classified elsewhere Both 1 5 8 circulatory system red 5, 1 2, 0 1, 0 1, 0 1, 1 -0.0797 1320 1 0 0.923 0.506 1.5 0.0932 18000 1 0 1.1 0.375 1.18 PRS_PLINK_0.000251188643150958 443.8 Other specified peripheral vascular diseases Both 3 27 8 circulatory system red 27, 3 7, 0 7, 0 6, 2 7, 1 1.62 1.06 0.127 0.896 5.08 0.576 954 1.37 1.82 0.452 0.345 3.93 0.192 1240 1.48 2.09 0.48 0.319 4.38 0.145 280 PRS_PLINK_0.000251188643150958 443.9 Peripheral vascular disease, unspecified Both 3 23 8 circulatory system red 23, 3 6, 0 6, 0 5, 2 6, 1 1.31 0.952 0.169 0.773 3.71 0.684 119 1.12 1.66 0.498 0.302 3.08 0.201 92.1 1.46 2.58 0.572 0.242 4.29 0.00657 3820 PRS_PLINK_0.000251188643150958 444 Arterial embolism and thrombosis Both 1 13 8 circulatory system red 13, 1 4, 0 3, 0 3, 1 3, 0 -0.0223 2.05 0.991 0.004 0.978 0.00145 102 -0.0615 6220 1 0 0.94 0.0443 8.38 PRS_PLINK_0.000251188643150958 444.1 Arterial embolism and thrombosis of lower extremity artery Both 0 4 8 circulatory system red 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 444.2 Embolism and thrombosis of abdominal aorta Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_0.000251188643150958 446 Polyarteritis nodosa and allied conditions Both 1 10 8 circulatory system red 10, 1 3, 0 2, 0 2, 1 3, 0 -2.35 33.4 0.944 0.025 0.0955 0.0756 0.121 0.000769 113 1 0 1 0.449 1.31 PRS_PLINK_0.000251188643150958 446.4 Wegener's granulomatosis Both 0 3 8 circulatory system red 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 446.5 Giant cell arteritis Both 1 1 8 circulatory system red 1, 1 0.0494 56.4 0.999 0 1.05 0.938 1.08 PRS_PLINK_0.000251188643150958 446.9 Arteritis NOS Both 1 4 8 circulatory system red 4, 1 1, 0 1, 1 1, 0 1, 0 0.461 4550 1 0 1.59 0.431 4.26 -0.269 4640 1 0 0.764 0.546 1.82 PRS_PLINK_0.000251188643150958 447 Other disorders of arteries and arterioles Both 3 23 8 circulatory system red 23, 3 6, 0 6, 0 5, 1 6, 2 0.68 0.737 0.356 0.449 1.97 0.52 42.7 0.513 4.47 0.909 0.042 1.67 1.91e-05 12800 2.57 2.16 0.235 0.63 13 0.674 68400 PRS_PLINK_0.000251188643150958 447.1 Stricture of artery Both 1 5 8 circulatory system red 5, 1 2, 0 1, 0 1, 0 1, 1 0.105 3360 1 0 1.11 0.48 1.45 0.0248 14000 1 0 1.03 0.263 1.07 PRS_PLINK_0.000251188643150958 447.7 Aortic ectasia Both 0 11 8 circulatory system red 11, 0 3 3 2 3 PRS_PLINK_0.000251188643150958 448 Disease of capillaries Both 1 13 8 circulatory system red 13, 1 3, 0 3, 0 3, 1 3, 0 -0.0847 0.938 0.928 0.032 0.919 0.152 11 0.106 947 1 0 1.11 0.746 2.51 PRS_PLINK_0.000251188643150958 450 Noninfectious disorders of lymphatic channels Both 1 22 8 circulatory system red 22, 1 6, 0 5, 1 5, 0 6, 0 -0.071 0.897 0.937 0.028 0.931 0.143 5.42 0.738 5.04 0.883 0.054 2.09 0.000366 15100 PRS_PLINK_0.000251188643150958 451 Phlebitis and thrombophlebitis Both 3 6 8 circulatory system red 6, 3 2, 2 1, 1 1, 0 2, 0 -1.25 2570 1 0 0.287 0.0286 0.0415 -0.00647 56.7 1 0 0.994 0.943 1.19 0.00443 68.4 1 0 1 0.76 1.09 0.307 2610 1 0 1.36 0.000407 459000 PRS_PLINK_0.000251188643150958 451.2 Phlebitis and thrombophlebitis of lower extremities Both 2 2 8 circulatory system red 2, 2 1, 2 1, 0 1, 2 1, 0 0.608 3750 1 0 1.84 0.562 1.92 0.517 6770 1 0 1.68 0.375 55.8 PRS_PLINK_0.000251188643150958 452 Other venous embolism and thrombosis Both 5 30 8 circulatory system red 30, 5 8, 1 7, 1 7, 0 8, 3 0.625 0.523 0.232 0.635 1.87 0.72 8.43 -0.262 2.26 0.908 0.042 0.77 0.00266 47.3 0.0154 1.72 0.993 0.003 1.02 0.0359 25.1 2.54 1.85 0.169 0.771 12.7 0.756 6.4e+08 PRS_PLINK_0.000251188643150958 452.1 Iatrogenic pulmonary embolism and infarction Both 0 6 8 circulatory system red 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 452.2 Deep vein thrombosis [DVT] Both 4 23 8 circulatory system red 23, 4 6, 1 6, 1 5, 0 6, 2 0.829 0.924 0.369 0.433 2.29 0.49 125 -0.116 3.47 0.973 0.012 0.89 0.00122 1720 -0.0653 1.96 0.973 0.012 0.937 0.00621 34.3 1.37 2.07 0.509 0.293 3.92 0.194 1130 PRS_PLINK_0.000251188643150958 452.8 Postphlebitic syndrome Both 0 1 8 circulatory system red 1, 0 PRS_PLINK_0.000251188643150958 453 Chronic venous hypertension Both 0 3 8 circulatory system red 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 454 Varicose veins Both 5 23 8 circulatory system red 23, 5 6, 1 6, 1 5, 2 6, 1 -0.11 0.855 0.898 0.047 0.896 0.0441 611 1.16 3.01 0.701 0.155 3.18 0.0198 712000 0.294 2.86 0.918 0.037 1.34 0.000199 2970000 -1.15 2.77 0.679 0.168 0.317 0.000393 142 PRS_PLINK_0.000251188643150958 454.1 Varicose veins of lower extremity Both 4 19 8 circulatory system red 19, 4 5, 0 5, 1 4, 2 5, 1 0.128 0.922 0.89 0.051 1.14 0.0209 31.8 0.495 6.45 0.939 0.027 1.64 1.67e-05 113000 -0.226 2.37 0.924 0.034 0.798 0.00756 36.8 0.113 247 1 0 1.12 0.695 1.17 PRS_PLINK_0.000251188643150958 454.11 Varicose veins of lower extremity, symptomtic Both 4 15 8 circulatory system red 15, 4 4, 0 4, 1 3, 2 4, 1 -0.207 1.12 0.853 0.069 0.813 0.0725 14.4 0.844 28.7 0.977 0.01 2.32 0.0453 676 1.11 359 0.998 0.001 3.05 3.94 16.8 -0.407 1060000 1 0 0.666 0.296 3.25 PRS_PLINK_0.000251188643150958 455 Hemorrhoids Both 16 28 8 circulatory system red 28, 16 6, 2 7, 7 7, 3 7, 4 0.0199 0.523 0.97 0.013 1.02 0.365 3.08 1.82 1.52 0.232 0.634 6.14 0.558 339 1.1 2.08 0.595 0.225 3.02 0.0461 80.9 -2.69 2.99 0.367 0.435 0.0677 4.19e-06 37.9 PRS_PLINK_0.000251188643150958 456 Chronic venous insufficiency [CVI] Both 8 24 8 circulatory system red 24, 8 6, 0 6, 3 6, 2 6, 3 1.14 0.961 0.238 0.624 3.11 0.381 112 2.24 2.09 0.284 0.546 9.37 0.326 17400 0.314 1.96 0.873 0.059 1.37 0.0118 275 1.21 2.65 0.648 0.188 3.35 0.00357 26000 PRS_PLINK_0.000251188643150958 457 Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin Both 1 12 8 circulatory system red 12, 1 3, 0 3, 0 3, 1 3, 0 0.684 1.94 0.725 0.14 1.98 0.0963 1450 0.0292 1850 1 0 1.03 0.673 1.64 PRS_PLINK_0.000251188643150958 457.2 Encounter for long-term (current) use of antiplatelets/antithrombotics Both 0 2 8 circulatory system red 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 457.3 Encounter for long-term (current) use of aspirin Both 1 11 8 circulatory system red 11, 1 3, 0 3, 0 2, 1 3, 0 0.201 2.31 0.931 0.031 1.22 0.032 531 0.053 2740 1 0 1.05 0.654 1.1 PRS_PLINK_0.000251188643150958 458 Hypotension Both 3 38 8 circulatory system red 38, 3 10, 1 9, 2 9, 0 10, 0 -0.109 0.691 0.874 0.058 0.896 0.126 4.86 1.11 1.45 0.445 0.352 3.02 0.269 243 0.165 1.75 0.925 0.034 1.18 0.0184 327 -0.332 1.82 0.855 0.068 0.717 0.000514 22.9 PRS_PLINK_0.000251188643150958 458.1 Orthostatic hypotension Both 0 19 8 circulatory system red 19, 0 5 5 4 5 PRS_PLINK_0.000251188643150958 458.2 Iatrogenic hypotension Both 0 12 8 circulatory system red 12, 0 3 3 3 3 PRS_PLINK_0.000251188643150958 458.9 Hypotension NOS Both 3 35 8 circulatory system red 35, 3 9, 1 9, 2 8, 0 9, 0 -0.0467 0.69 0.946 0.024 0.954 0.109 5.04 1.18 1.49 0.428 0.369 3.26 0.276 231 -0.0361 1.65 0.983 0.008 0.965 0.0171 78.4 -0.646 2.11 0.759 0.12 0.524 0.000146 16 PRS_PLINK_0.000251188643150958 459 Other disorders of circulatory system Both 9 49 8 circulatory system red 49, 9 12, 2 12, 2 12, 1 12, 4 0.563 0.464 0.225 0.647 1.76 0.687 5.49 0.341 1.26 0.787 0.104 1.41 0.107 16.5 -0.242 1.27 0.849 0.071 0.785 0.0198 11.2 1.26 1.23 0.309 0.511 3.51 0.404 100 PRS_PLINK_0.000251188643150958 459.1 Hemorrhage NOS Both 0 11 8 circulatory system red 11, 0 3 3 2 3 PRS_PLINK_0.000251188643150958 459.7 Blood vessel replaced Both 1 12 8 circulatory system red 12, 1 3, 1 3, 0 3, 0 3, 0 -0.153 3.11 0.961 0.017 0.859 0.000371 495 1.23 1330 0.999 0 3.41 0.000863 9820 0.0807 1860 1 0 1.08 0.196 1.87 0.417 6850 1 0 1.52 0.273 19.9 PRS_PLINK_0.000251188643150958 459.9 Circulatory disease NEC Both 9 46 8 circulatory system red 46, 9 11, 2 11, 2 11, 0 12, 5 0.736 0.545 0.177 0.751 2.09 0.711 7.72 0.401 1.42 0.778 0.109 1.49 0.103 22.5 -0.738 1.41 0.6 0.222 0.478 0.000534 6.4 1.37 1.24 0.268 0.571 3.94 0.467 70.9 PRS_PLINK_0.000251188643150958 464 Acute sinusitis Both 11 34 9 respiratory coral4 34, 11 8, 2 8, 5 8, 3 9, 1 0.00888 0.449 0.984 0.007 1.01 0.401 2.42 2.22 2.35 0.345 0.462 9.16 0.234 115000 0.814 1.72 0.635 0.197 2.26 0.00702 53.6 -0.649 2.12 0.76 0.119 0.522 1.94e-05 341 PRS_PLINK_0.000251188643150958 465 Acute upper respiratory infections of multiple or unspecified sites Both 24 36 9 respiratory coral4 36, 24 8, 2 9, 10 9, 7 9, 5 0.126 0.297 0.671 0.173 1.13 0.657 1.96 2 1.27 0.114 0.942 7.39 0.963 185 1.02 1.51 0.499 0.302 2.77 0.0534 61.8 -0.244 1.39 0.861 0.065 0.783 0.0491 9.07 PRS_PLINK_0.000251188643150958 465.2 Acute pharyngitis Both 17 37 9 respiratory coral4 37, 17 9, 1 9, 7 9, 6 9, 3 0.257 0.319 0.42 0.377 1.29 0.734 2.37 2.04 1.56 0.191 0.72 7.73 0.624 1910 1.42 1.55 0.359 0.445 4.15 0.0955 100 -0.975 1.93 0.613 0.212 0.377 0.000814 12 PRS_PLINK_0.000251188643150958 465.4 Acute laryngitis and tracheitis Both 0 3 9 respiratory coral4 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 470 Septal Deviations/Turbinate Hypertrophy Both 2 22 9 respiratory coral4 22, 2 5, 0 5, 1 5, 1 6, 0 -0.111 0.557 0.842 0.075 0.895 0.00959 2.87 0.84 1.97 0.67 0.174 2.32 0.128 154 0.273 1.92 0.887 0.052 1.31 0.093 28.8 PRS_PLINK_0.000251188643150958 471 Nasal polyps Both 2 5 9 respiratory coral4 5, 2 2, 2 1, 0 1, 0 1, 0 -0.0124 53.3 1 0 0.988 0.84 1.14 1.61e-05 4450 1 0 1 0.0883 3.42 0.0132 1140 1 0 1.01 0.79 1.3 0.064 4440 1 0 1.07 0.346 3.5 PRS_PLINK_0.000251188643150958 472 Chronic pharyngitis and nasopharyngitis Both 5 23 9 respiratory coral4 23, 5 6, 3 6, 2 5, 0 6, 0 -1.69 1.22 0.166 0.781 0.185 0.00742 1.61 -1.23 2.56 0.629 0.201 0.291 0.000101 341 -0.627 2.07 0.762 0.118 0.534 0.00743 64.7 -0.879 1.66 0.596 0.225 0.415 0.00315 4.94 PRS_PLINK_0.000251188643150958 473 Diseases of the larynx and vocal cords Both 5 26 9 respiratory coral4 26, 5 6, 1 6, 1 6, 0 7, 3 -0.276 0.733 0.706 0.151 0.758 0.11 4.86 -0.46 2.23 0.837 0.077 0.632 0.00523 25.1 -0.189 1.74 0.914 0.039 0.828 0.0313 353 -0.965 1.92 0.616 0.21 0.381 0.00277 12.5 PRS_PLINK_0.000251188643150958 473.1 Chronic laryngitis Both 0 1 9 respiratory coral4 1, 0 PRS_PLINK_0.000251188643150958 473.3 Paralysis/spasm of vocal cords or larynx Both 1 4 9 respiratory coral4 4, 1 1, 0 1, 0 1, 0 1, 1 2.89 3120 0.999 0 17.9 0.00557 271000 -0.0718 62.7 0.999 0 0.931 0.887 1.08 PRS_PLINK_0.000251188643150958 473.4 Voice disturbance Both 3 19 9 respiratory coral4 19, 3 4, 0 5, 1 4, 0 5, 2 -0.0576 0.822 0.944 0.025 0.944 0.144 7.96 -0.0666 1770 1 0 0.936 0.553 1.5 -0.604 5.01 0.904 0.044 0.547 0.000383 27500 PRS_PLINK_0.000251188643150958 474 Acute and chronic tonsillitis Both 3 13 9 respiratory coral4 13, 3 3, 1 3, 1 3, 0 3, 1 -0.427 0.614 0.487 0.312 0.653 0.0969 1.73 -0.421 20400000 1 0 0.657 0.000113 103000 0.0426 280 1 0 1.04 0.751 1.53 0.135 98.3 0.999 0 1.14 0.188 2.03 PRS_PLINK_0.000251188643150958 474.1 Acute tonsillitis Both 1 8 9 respiratory coral4 8, 1 2, 1 2, 0 2, 0 2, 0 0.0338 88.2 1 0 1.03 0.165 1.3 -0.752 6740 1 0 0.472 0.384 6.44 -1.61 1300 0.999 0 0.199 1.94e-10 30300000 -0.99 3360 1 0 0.371 5.71e-07 1090000 PRS_PLINK_0.000251188643150958 474.2 Chronic tonsillitis and adenoiditis Both 3 8 9 respiratory coral4 8, 3 2, 2 2, 0 2, 0 2, 1 -0.38 1.15 0.74 0.131 0.684 0.0262 3.6 -0.000373 49.7 1 0 1 0.736 1.23 0.213 1540 1 0 1.24 0.572 1.34 0.348 812 1 0 1.42 0.314 5.26 PRS_PLINK_0.000251188643150958 475 Chronic sinusitis Both 11 31 9 respiratory coral4 31, 11 7, 3 8, 2 7, 3 8, 3 -0.0528 0.433 0.903 0.044 0.949 0.406 2.1 -1.71 1.88 0.363 0.441 0.18 0.000773 3.77 -0.517 1.41 0.714 0.146 0.596 0.03 6.28 -0.831 1.65 0.614 0.212 0.436 0.0134 7.67 PRS_PLINK_0.000251188643150958 475.9 Postnasal drip Both 4 7 9 respiratory coral4 7, 4 2, 0 2, 1 1, 2 2, 1 2.8 7.34 0.703 0.153 16.4 6e-04 20.4 -0.00269 473 1 0 0.997 0.452 1.55 1.06 906 0.999 0 2.89 0.000367 4300 -5.27 3800 0.999 0 0.00513 5.18e-08 291000 PRS_PLINK_0.000251188643150958 476 Allergic rhinitis Both 24 32 9 respiratory coral4 32, 24 7, 9 8, 6 8, 5 8, 4 -0.151 0.333 0.65 0.187 0.86 0.442 1.56 -0.232 0.964 0.809 0.092 0.793 0.136 4.22 -0.424 1.04 0.684 0.165 0.654 0.0962 3.85 -0.677 1.04 0.513 0.29 0.508 0.0512 2.78 PRS_PLINK_0.000251188643150958 477 Epistaxis or throat hemorrhage Both 1 11 9 respiratory coral4 11, 1 3, 0 3, 1 2, 0 3, 0 -0.355 2.34 0.879 0.056 0.701 0.68 0.726 0.000102 568 1 0 1 0.37 1.69 PRS_PLINK_0.000251188643150958 478 Throat pain Both 1 5 9 respiratory coral4 5, 1 1, 0 1, 0 1, 1 1, 0 -0.954 320 0.998 0.001 0.385 0.0091 114 0.403 18900 1 0 1.5 0.273 159 PRS_PLINK_0.000251188643150958 479 Other upper respiratory disease Both 11 32 9 respiratory coral4 32, 11 7, 6 8, 2 8, 1 8, 2 -0.175 0.357 0.624 0.205 0.839 0.417 1.57 -1.21 1.37 0.378 0.423 0.299 0.018 2.96 -0.885 1.36 0.515 0.288 0.413 0.0226 3.78 0.59 1.71 0.731 0.136 1.8 0.077 59.5 PRS_PLINK_0.000251188643150958 480 Pneumonia Both 13 43 9 respiratory coral4 43, 13 10, 4 11, 2 10, 4 11, 3 -0.103 0.399 0.797 0.099 0.902 0.371 1.86 -0.414 1.25 0.74 0.131 0.661 0.0464 15.9 0.468 1.13 0.679 0.168 1.6 0.177 14.6 -2.09 1.65 0.205 0.687 0.124 0.000725 1.7 PRS_PLINK_0.000251188643150958 480.1 Bacterial pneumonia Both 5 13 9 respiratory coral4 13, 5 4, 2 3, 0 3, 1 3, 2 -0.486 1.14 0.67 0.174 0.615 0.498 3.4 0.208 3.63 0.954 0.02 1.23 1.19 1.36 2.79 12.9 0.828 0.082 16.3 0.00587 18.5 2.72 4.3 0.528 0.277 15.1 0.0604 19.4 PRS_PLINK_0.000251188643150958 480.11 Pneumococcal pneumonia Both 3 5 9 respiratory coral4 5, 3 2, 1 1, 0 1, 0 1, 2 0.253 33.1 0.994 0.003 1.29 1.4 2.73 0.000979 455 1 0 1 0.000101 463 -0.468 14700000 1 0 0.627 0.0347 50.4 0.126 3150 1 0 1.13 0.0542 28.3 PRS_PLINK_0.000251188643150958 480.12 Pseudomonal pneumonia Both 1 2 9 respiratory coral4 2, 1 1, 1 1, 0 1, 1 1, 0 0.0398 211 1 0 1.04 0.807 3.56 0.0556 187 1 0 1.06 0.857 1.35 PRS_PLINK_0.000251188643150958 480.2 Viral pneumonia Both 1 7 9 respiratory coral4 7, 1 2, 0 2, 0 1, 0 2, 1 0.00803 196 1 0 1.01 0.847 1.23 -0.0525 1490 1 0 0.949 0.253 13.7 PRS_PLINK_0.000251188643150958 480.3 Pneumonia due to fungus (mycoses) Both 2 3 9 respiratory coral4 3, 2 1, 1 1, 1 1, 0 1, 1 0.0671 5740 1 0 1.07 0.35 3.53 0.0193 13600 1 0 1.02 0.534 1.42 0.0508 305 1 0 1.05 0.897 1.68 PRS_PLINK_0.000251188643150958 480.5 Bronchopneumonia and lung abscess Both 0 1 9 respiratory coral4 1, 0 PRS_PLINK_0.000251188643150958 481 Influenza Both 4 22 9 respiratory coral4 22, 4 5, 1 5, 1 5, 1 6, 1 -0.417 0.621 0.502 0.299 0.659 0.0882 2.19 -1.59 6.04 0.792 0.101 0.204 5.95e-07 56100 1.58 9.88 0.873 0.059 4.88 6.87e-06 25300000 -1.09 2.24 0.627 0.203 0.336 0.000294 9.95 PRS_PLINK_0.000251188643150958 483 Acute bronchitis and bronchiolitis Both 9 35 9 respiratory coral4 35, 9 9, 2 9, 4 8, 2 9, 1 -0.218 0.468 0.642 0.193 0.804 0.299 1.85 1.75 1.38 0.204 0.691 5.74 0.66 1730 1.98 2 0.321 0.493 7.27 0.00591 26600 -0.344 1.37 0.801 0.096 0.709 0.0532 7.04 PRS_PLINK_0.000251188643150958 495 Asthma Both 15 45 9 respiratory coral4 45, 15 11, 7 11, 3 11, 2 11, 3 -0.282 0.382 0.461 0.337 0.754 0.35 1.54 -0.654 0.931 0.482 0.317 0.52 0.0897 2.86 -0.494 1.1 0.655 0.184 0.61 0.0693 4.67 -0.738 0.91 0.418 0.379 0.478 0.0857 2.16 PRS_PLINK_0.000251188643150958 495.1 Chronic obstructive asthma Both 1 3 9 respiratory coral4 3, 1 1, 0 1, 1 1, 0 1, 0 0.236 19000 1 0 1.27 0.289 10.6 -0.0188 109 1 0 0.981 0.781 1.24 PRS_PLINK_0.000251188643150958 495.11 Chronic obstructive asthma with exacerbation Both 1 3 9 respiratory coral4 3, 1 1, 0 1, 0 0, 1 1, 0 0.223 16000 1 0 1.25 0.32 11.8 -0.0205 110 1 0 0.98 0.799 1.19 PRS_PLINK_0.000251188643150958 495.2 Asthma with exacerbation Both 7 26 9 respiratory coral4 26, 7 6, 1 6, 4 6, 0 7, 2 0.0508 0.639 0.937 0.028 1.05 0.281 3.72 1.82 1.86 0.329 0.483 6.16 0.305 17900 -2.57 7.22 0.722 0.142 0.0762 0.0564 5310 0.99 3.58 0.782 0.107 2.69 0.00627 130000 PRS_PLINK_0.000251188643150958 496 Chronic airway obstruction Both 7 31 9 respiratory coral4 31, 7 8, 4 8, 3 7, 0 8, 0 -0.706 0.616 0.252 0.599 0.494 0.122 1.61 -0.0758 1.07 0.944 0.025 0.927 0.135 5.64 -0.759 1.82 0.677 0.169 0.468 0.00158 11 -2.28 1.87 0.223 0.651 0.103 7.63e-07 1.82 PRS_PLINK_0.000251188643150958 496.1 Emphysema Both 1 12 9 respiratory coral4 12, 1 3, 0 3, 1 3, 0 3, 0 0.433 1.31 0.741 0.13 1.54 0.114 587 0.0165 446 1 0 1.02 0.0972 8.67 PRS_PLINK_0.000251188643150958 496.2 Chronic bronchitis Both 3 22 9 respiratory coral4 22, 3 6, 2 5, 1 5, 0 6, 0 -0.786 1.02 0.439 0.357 0.456 0.00239 7.71 -0.69 3.1 0.824 0.084 0.501 2.79e-06 4550 1.84 4.45 0.68 0.168 6.29 0.000702 1e+06 -0.739 2.91 0.8 0.097 0.478 1e-04 520 PRS_PLINK_0.000251188643150958 496.21 Obstructive chronic bronchitis Both 2 20 9 respiratory coral4 20, 2 5, 2 5, 0 5, 0 5, 0 -0.537 1.06 0.613 0.213 0.584 0.0092 6.19 0.0415 2.58 0.987 0.006 1.04 0.0014 109 1.31 4 0.743 0.129 3.71 0.00501 14000 -0.446 2.61 0.864 0.063 0.64 0.00021 323 PRS_PLINK_0.000251188643150958 496.3 Bronchiectasis Both 4 2 9 respiratory coral4 2, 4 1, 3 1, 1 1, 3 1, 1 0.0366 2040 1 0 1.04 0.294 1.43 0.285 1580 1 0 1.33 0.456 13.3 PRS_PLINK_0.000251188643150958 497 Bronchitis Both 5 28 9 respiratory coral4 28, 5 7, 4 7, 1 7, 0 7, 0 -2.19 1.17 0.0617 1.21 0.112 0.00078 0.838 -1.02 1.57 0.517 0.287 0.362 0.000435 6.17 -2.46 2.34 0.293 0.533 0.0857 5.39e-10 2.56 -2.2 2.23 0.324 0.489 0.111 0.00096 3.17 PRS_PLINK_0.000251188643150958 498 Acute bronchospasm Both 2 7 9 respiratory coral4 7, 2 2, 0 2, 1 1, 0 2, 1 -0.109 406 1 0 0.897 0.471 1.52 -1.63 1520 0.999 0 0.196 2.29e-06 1940 -2.34 5010 1 0 0.0966 0.00377 0.242 PRS_PLINK_0.000251188643150958 499 Cystic fibrosis Both 2 5 9 respiratory coral4 5, 2 2, 2 1, 0 1, 0 1, 0 -0.0651 1010000 1 0 0.937 0.16 3.41 -0.664 76500000 1 0 0.515 0.00485 0.878 -0.48 2360 1 0 0.619 0.00549 47.5 -0.264 953 1 0 0.768 0.0167 18.2 PRS_PLINK_0.000251188643150958 500 Lung disease due to external agents Both 1 2 9 respiratory coral4 2, 1 1, 0 1, 1 1, 0 1, 1 0.00297 33.2 1 0 1 0.912 1.1 -0.00251 19 1 0 0.997 0.947 1.39 PRS_PLINK_0.000251188643150958 500.1 Extrinsic allergic alveolitis Both 1 1 9 respiratory coral4 1, 1 0.0222 140 1 0 1.02 0.791 1.36 PRS_PLINK_0.000251188643150958 501 Pneumonitis due to inhalation of food or vomitus Both 0 10 9 respiratory coral4 10, 0 3 2 2 3 PRS_PLINK_0.000251188643150958 502 Postinflammatory pulmonary fibrosis Both 2 7 9 respiratory coral4 7, 2 2, 0 2, 0 1, 1 2, 1 -0.103 2350000 1 0 0.902 0.104 4.84 -0.183 79500 1 0 0.833 0.00522 4.94 -0.00875 972 1 0 0.991 0.719 1.4 PRS_PLINK_0.000251188643150958 503 Pulmonary congestion and hypostasis Both 0 11 9 respiratory coral4 11, 0 3 3 2 3 PRS_PLINK_0.000251188643150958 504 Other alveolar and parietoalveolar pneumonopathy Both 2 3 9 respiratory coral4 3, 2 1, 0 1, 1 1, 1 1, 0 -3.06 1780 0.999 0.001 0.047 9.24e-16 4.52e+13 -0.00162 25.3 1 0 0.998 0.94 1.05 0.00725 25.1 1 0 1.01 0.622 1.2 PRS_PLINK_0.000251188643150958 504.1 Idiopathic fibrosing alveolitis Both 2 1 9 respiratory coral4 1, 2 -0.0229 102 1 0 0.977 0.525 1.65 PRS_PLINK_0.000251188643150958 505 Other pulmonary inflamation or edema Both 4 19 9 respiratory coral4 19, 4 5, 1 5, 0 4, 1 5, 2 0.957 1.12 0.392 0.406 2.6 0.00322 203 0.144 2.8 0.959 0.018 1.15 1.07 1.23 -0.134 4.4 0.976 0.011 0.874 0.000366 257000 2.11 2.95 0.476 0.323 8.23 0.0192 2680 PRS_PLINK_0.000251188643150958 506 Empyema and pneumothorax Both 2 23 9 respiratory coral4 23, 2 6, 0 6, 0 5, 1 6, 1 0.126 0.918 0.891 0.05 1.13 0.0138 14.5 0.00623 1.97 0.997 0.001 1.01 0.0367 28.6 1.49 3.98 0.708 0.15 4.45 0.0529 663 PRS_PLINK_0.000251188643150958 507 Pleurisy; pleural effusion Both 1 28 9 respiratory coral4 28, 1 7, 1 7, 0 7, 0 7, 0 -0.253 0.719 0.725 0.14 0.777 0.0261 2.93 -0.145 3.53 0.967 0.014 0.865 6.02e-05 8580 -0.763 1.92 0.691 0.161 0.466 0.00164 11 0.144 1.88 0.939 0.027 1.15 0.0013 44.3 PRS_PLINK_0.000251188643150958 508 Pulmonary collapse; interstitial and compensatory emphysema Both 1 25 9 respiratory coral4 25, 1 7, 0 6, 0 6, 0 6, 1 0.188 0.841 0.824 0.084 1.21 0.0411 16.2 0.653 2.38 0.783 0.106 1.92 0.0232 379 PRS_PLINK_0.000251188643150958 509 Respiratory failure, insufficiency, arrest Both 5 37 9 respiratory coral4 37, 5 10, 1 9, 1 9, 2 9, 1 0.19 0.636 0.765 0.116 1.21 0.325 5.28 0.767 1.59 0.629 0.201 2.15 0.0523 1480 0.664 1.24 0.593 0.227 1.94 0.142 59.4 0.547 1.79 0.76 0.119 1.73 0.00249 2820 PRS_PLINK_0.000251188643150958 509.1 Respiratory failure Both 1 24 9 respiratory coral4 24, 1 6, 0 6, 1 6, 0 6, 0 -0.0508 0.76 0.947 0.024 0.95 0.0603 5.63 1.35 3 0.654 0.184 3.84 0.0328 1730 PRS_PLINK_0.000251188643150958 509.2 Respiratory insufficiency Both 0 14 9 respiratory coral4 14, 0 4 3 3 4 PRS_PLINK_0.000251188643150958 509.3 Pulmonary insufficiency or respiratory failure following trauma and surgery Both 1 13 9 respiratory coral4 13, 1 4, 0 3, 1 3, 0 3, 0 0.886 1.67 0.596 0.225 2.42 0.212 279 0.0406 853 1 0 1.04 0.781 1.44 PRS_PLINK_0.000251188643150958 509.8 Dependence on respirator [Ventilator] or supplemental oxygen Both 3 19 9 respiratory coral4 19, 3 5, 0 5, 0 4, 2 5, 1 1.18 1.03 0.255 0.594 3.25 0.474 203 -1.9 5.6 0.734 0.134 0.149 0.12 0.194 1.58 15.9 0.921 0.036 4.85 0.000111 412000 PRS_PLINK_0.000251188643150958 510 Other diseases of lung Both 9 40 9 respiratory coral4 40, 9 10, 6 10, 0 10, 2 10, 1 -0.773 0.527 0.143 0.846 0.462 0.149 1.19 -1.43 1.22 0.241 0.619 0.238 0.000432 1.6 -1.38 1.18 0.243 0.614 0.252 0.0165 1.69 -0.933 1.29 0.468 0.33 0.393 0.0213 3.22 PRS_PLINK_0.000251188643150958 510.2 Lung transplant Both 0 2 9 respiratory coral4 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 512 Other symptoms of respiratory system Both 31 33 9 respiratory coral4 33, 31 8, 3 8, 9 8, 13 8, 6 0.291 0.295 0.324 0.489 1.34 0.779 2.34 1.78 1.35 0.187 0.729 5.92 0.611 88.2 0.717 1 0.473 0.325 2.05 0.357 13.1 0.788 1.26 0.533 0.273 2.2 0.258 27.1 PRS_PLINK_0.000251188643150958 512.1 Wheezing Both 5 16 9 respiratory coral4 16, 5 4, 0 4, 1 4, 2 4, 2 0.381 1.28 0.765 0.116 1.46 0.00939 63 -1.45 5730 1 0 0.235 0.102 0.677 1.54 13.1 0.907 0.042 4.65 0.00268 11000 1.15 38.8 0.976 0.01 3.16 0.0998 2100 PRS_PLINK_0.000251188643150958 512.2 Painful respiration Both 5 25 9 respiratory coral4 25, 5 6, 1 6, 0 6, 3 6, 1 0.416 0.482 0.388 0.411 1.52 0.669 4.42 0.142 2.58 0.956 0.019 1.15 0.0106 90.1 -0.537 1.94 0.782 0.107 0.584 0.0183 17 0.482 3.17 0.879 0.056 1.62 0.0134 303 PRS_PLINK_0.000251188643150958 512.3 Abnormal chest sounds Both 0 3 9 respiratory coral4 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 512.7 Shortness of breath Both 14 33 9 respiratory coral4 33, 14 8, 3 8, 3 8, 7 8, 1 -0.0185 0.401 0.963 0.016 0.982 0.442 2.1 0.805 1.55 0.605 0.219 2.24 0.124 263 0.272 1.06 0.798 0.098 1.31 0.207 8.63 -1.03 2.06 0.616 0.21 0.356 0.00317 13 PRS_PLINK_0.000251188643150958 512.8 Cough Both 22 33 9 respiratory coral4 33, 22 8, 3 8, 8 8, 7 8, 4 0.129 0.353 0.714 0.146 1.14 0.575 2.17 1.78 1.35 0.187 0.729 5.92 0.611 88.2 0.481 1.11 0.664 0.178 1.62 0.251 12.4 -0.0578 1.61 0.971 0.013 0.944 0.0436 15.4 PRS_PLINK_0.000251188643150958 512.9 Other dyspnea Both 18 33 9 respiratory coral4 33, 18 8, 3 8, 5 8, 8 8, 2 0.167 0.345 0.629 0.201 1.18 0.617 2.24 2.94 2.03 0.148 0.831 18.9 0.687 23.9 0.779 1.16 0.503 0.299 2.18 0.307 19.5 0.531 1.5 0.724 0.141 1.7 0.127 46.2 PRS_PLINK_0.000251188643150958 513 Respiratory abnormalities Both 21 43 9 respiratory coral4 43, 21 10, 4 11, 4 10, 9 11, 4 0.115 0.317 0.717 0.145 1.12 0.607 2.04 1.02 1.3 0.433 0.363 2.78 0.299 108 0.981 0.941 0.297 0.527 2.67 0.532 15.9 0.711 1.19 0.549 0.26 2.04 0.237 22.4 PRS_PLINK_0.000251188643150958 513.3 Hypoventilation Both 1 10 9 respiratory coral4 10, 1 2, 0 2, 0 2, 0 3, 1 -0.538 1.57 0.732 0.136 0.584 0.0497 93.6 0.111 2150 1 0 1.12 0.52 3.13 PRS_PLINK_0.000251188643150958 513.31 Apnea Both 1 5 9 respiratory coral4 5, 1 2, 0 1, 0 1, 1 1, 0 0.014 424 1 0 1.01 1.12 2.68 0.246 1150 1 0 1.28 0.535 2.88 PRS_PLINK_0.000251188643150958 513.32 Orthopnea Both 0 2 9 respiratory coral4 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 513.4 Hyperventilation Both 1 2 9 respiratory coral4 2, 1 1, 0 1, 1 1, 0 1, 1 0.0499 68.4 0.999 0 1.05 0.681 1.1 0.0567 94.2 1 0 1.06 0.291 1.14 PRS_PLINK_0.000251188643150958 513.8 Disorders of diaphragm Both 0 3 9 respiratory coral4 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 514 Abnormal findings examination of lungs Both 6 41 9 respiratory coral4 41, 6 11, 4 10, 0 10, 0 10, 2 -0.658 0.684 0.336 0.474 0.518 0.101 2.48 0.341 1.6 0.832 0.08 1.41 0.0377 122 -1.01 1.48 0.493 0.307 0.364 0.000695 6.11 -0.487 1.52 0.748 0.126 0.615 0.00215 41.7 PRS_PLINK_0.000251188643150958 514.1 Abnormal results of function study of pulmonary system Both 0 2 9 respiratory coral4 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 514.2 Solitary pulmonary nodule Both 3 25 9 respiratory coral4 25, 3 7, 2 6, 1 6, 0 6, 0 -0.508 0.776 0.512 0.29 0.602 0.0495 3.91 -0.274 1.82 0.88 0.055 0.76 0.00243 19.7 -0.114 2.21 0.959 0.018 0.892 0.0153 52.3 -0.582 2.15 0.786 0.105 0.559 0.00483 17.2 PRS_PLINK_0.000251188643150958 516 Abnormal sputum Both 3 10 9 respiratory coral4 10, 3 3, 3 2, 0 2, 0 3, 0 -0.405 0.973 0.678 0.169 0.667 0.051 5.54 0.233 622 1 0 1.26 0.589 3.42 -0.248 927 1 0 0.78 0.175 1.18 0.202 36.7 0.996 0.002 1.22 1.06 10500 PRS_PLINK_0.000251188643150958 516.1 Hemoptysis Both 3 11 9 respiratory coral4 11, 3 3, 2 3, 1 2, 0 3, 0 -0.175 0.876 0.842 0.075 0.84 0.0391 6.66 2.6 4050 0.999 0 13.4 0.000346 67000 0.324 52500000 1 0 1.38 0.137 97.4 0.0696 481 1 0 1.07 0.257 8.13 PRS_PLINK_0.000251188643150958 519 Other diseases of respiratory system, not elsewhere classified Both 8 54 9 respiratory coral4 54, 8 13, 4 13, 2 13, 1 14, 1 -1.13 0.587 0.0545 1.263 0.324 0.0719 1 -0.263 1.16 0.821 0.086 0.769 0.0542 17.7 0.266 1.58 0.866 0.062 1.3 7.69e-06 106 -4.54 2.42 0.06 1.222 0.0106 1.72e-08 0.671 PRS_PLINK_0.000251188643150958 519.1 Tracheostomy complications Both 0 1 9 respiratory coral4 1, 0 PRS_PLINK_0.000251188643150958 519.2 Respiratory complications Both 0 4 9 respiratory coral4 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 519.8 Other diseases of respiratory system, NEC Both 4 23 9 respiratory coral4 23, 4 5, 3 6, 1 5, 0 6, 0 -0.476 0.725 0.512 0.291 0.621 0.0221 4.35 1.47 2.33 0.528 0.277 4.34 0.0905 63100 -0.954 2.26 0.673 0.172 0.385 0.00821 11.6 -0.0562 2.65 0.983 0.007 0.945 4.73e-05 8880000 PRS_PLINK_0.000251188643150958 519.9 Symptoms involving respiratory system and other chest symptoms Both 6 43 9 respiratory coral4 43, 6 11, 3 11, 1 10, 1 11, 1 -0.695 0.585 0.235 0.629 0.499 0.0556 1.39 -1.95 1.88 0.299 0.524 0.143 0.000473 4.33 0.386 1.58 0.807 0.093 1.47 0.0133 1340 -2.54 2 0.204 0.69 0.0788 2.66e-05 2.9 PRS_PLINK_0.000251188643150958 520 Disorders of tooth development Both 0 8 10 digestive chartreuse4 8, 0 2 2 2 2 PRS_PLINK_0.000251188643150958 520.1 Hereditary disturbances in tooth structure Both 0 5 10 digestive chartreuse4 5, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 520.2 Disturbances in tooth eruption Both 0 9 10 digestive chartreuse4 9, 0 3 2 2 2 PRS_PLINK_0.000251188643150958 521 Diseases of hard tissues of teeth Both 0 13 10 digestive chartreuse4 13, 0 4 3 3 3 PRS_PLINK_0.000251188643150958 521.1 Dental caries Both 0 12 10 digestive chartreuse4 12, 0 3 3 3 3 PRS_PLINK_0.000251188643150958 522 Diseases of pulp and periapical tissues Both 1 7 10 digestive chartreuse4 7, 1 2, 1 2, 0 1, 0 2, 0 0.0215 11200000 1 0 1.02 1.77e-06 43500000 -0.622 5550 1 0 0.537 0.272 3.6 -0.15 1290 1 0 0.861 0.337 1.46 -0.666 4070 1 0 0.514 0.465 1.94 PRS_PLINK_0.000251188643150958 522.5 Periapical abscess Both 1 5 10 digestive chartreuse4 5, 1 2, 0 1, 1 1, 0 1, 0 0.0362 1020 1 0 1.04 0.83 1.75 -0.0789 33400 1 0 0.924 0.863 42.6 PRS_PLINK_0.000251188643150958 523 Gingival and periodontal diseases Both 0 10 10 digestive chartreuse4 10, 0 3 2 2 3 PRS_PLINK_0.000251188643150958 523.1 Gingivitis Both 0 3 10 digestive chartreuse4 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 523.3 Periodontitis (acute or chronic) Both 0 4 10 digestive chartreuse4 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 523.31 Acute periodontitis Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 523.32 Chronic periodontitis Both 0 1 10 digestive chartreuse4 1, 0 PRS_PLINK_0.000251188643150958 524 Dentofacial anomalies, including malocclusion Both 2 6 10 digestive chartreuse4 6, 2 2, 2 1, 0 1, 0 2, 0 -0.0317 29.5 0.999 0 0.969 0.825 0.94 27.5 5.09e+08 1 0 9.04e+11 1.75e-37 4.28e+67 -2.01 4620 1 0 0.134 3.99e-05 107 0.559 4190 1 0 1.75 0.171 22.7 PRS_PLINK_0.000251188643150958 524.3 Anomalies of tooth position/malocclusion Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 525 Other diseases of the teeth and supporting structures Both 1 17 10 digestive chartreuse4 17, 1 5, 1 4, 0 4, 0 4, 0 0.584 1.45 0.687 0.163 1.79 0.0484 245 0.764 71.6 0.991 0.004 2.15 0.000704 10900 -3.17 73.7 0.966 0.015 0.0419 0.036 1120 0.292 8.11 0.971 0.013 1.34 1.71 2.74 PRS_PLINK_0.000251188643150958 525.1 Loss of teeth or edentulism Both 0 7 10 digestive chartreuse4 7, 0 2 2 1 2 PRS_PLINK_0.000251188643150958 526 Diseases of the jaws Both 4 37 10 digestive chartreuse4 37, 4 9, 2 9, 0 9, 2 9, 0 -1.46 0.864 0.0901 1.045 0.231 0.000292 1.29 -1.11 1.56 0.477 0.321 0.331 5.5e-05 5.03 -1.56 1.94 0.42 0.377 0.209 1.4e-05 5.95 0.0186 2.28 0.993 0.003 1.02 0.00597 1.2e+08 PRS_PLINK_0.000251188643150958 526.1 Cysts of the jaws Both 1 6 10 digestive chartreuse4 6, 1 2, 1 1, 0 1, 0 2, 0 0.244 4130 1 0 1.28 0.253 13.5 0.0907 826 1 0 1.09 0.742 1.11 0.0888 2600 1 0 1.09 0.573 1.14 0.0232 2100 1 0 1.02 0.555 3.54 PRS_PLINK_0.000251188643150958 526.3 Anomalies of jaw size/symmetry Both 1 2 10 digestive chartreuse4 2, 1 1, 0 1, 1 1, 0 1, 1 0.0426 206 1 0 1.04 0.603 1.19 -0.00302 57.9 1 0 0.997 0.868 1.06 PRS_PLINK_0.000251188643150958 526.4 Temporomandibular joint disorders Both 2 20 10 digestive chartreuse4 20, 2 4, 1 5, 0 5, 1 5, 0 -0.67 0.887 0.45 0.347 0.511 0.000632 2.53 1.38 3.7 0.709 0.149 3.98 0.0196 1150 -2.14 2.83 0.449 0.348 0.117 0.0998 4.82 -0.147 190 0.999 0 0.863 2.65 44 PRS_PLINK_0.000251188643150958 526.41 Temporomandibular joint disorder, unspecified Both 2 17 10 digestive chartreuse4 17, 2 5, 1 4, 0 4, 1 4, 0 -1.08 1.38 0.434 0.363 0.34 0.000908 3.47 2.28 8.92 0.799 0.098 9.74 8.67 11 -1.34 6.89 0.846 0.072 0.263 0.0308 2.13 3.78 15.6 0.809 0.092 43.8 1.01e-08 1.93e+12 PRS_PLINK_0.000251188643150958 526.42 Arthralgia/ankylosis of temporomandibular joint Both 1 9 10 digestive chartreuse4 9, 1 2, 1 2, 0 2, 0 2, 0 2.18e-15 1.75 1 0 1 0.0398 14 -0.0461 2590 1 0 0.955 0.726 1.2 -0.127 17500 1 0 0.88 0.822 2.13 -0.0902 54100000 1 0 0.914 0.216 3.96 PRS_PLINK_0.000251188643150958 526.5 Inflammatory conditions of jaw Both 0 3 10 digestive chartreuse4 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 526.9 Jaw disease NOS Both 0 8 10 digestive chartreuse4 8, 0 2 2 2 2 PRS_PLINK_0.000251188643150958 527 Diseases of the salivary glands Both 3 18 10 digestive chartreuse4 18, 3 5, 0 4, 2 4, 0 5, 1 -0.763 1.04 0.463 0.334 0.466 0.0188 2.72 -0.743 3.76 0.843 0.074 0.476 0.000477 8690 -1.85 23 0.936 0.029 0.157 2.88e-14 9.75e+11 PRS_PLINK_0.000251188643150958 527.1 Hypertrophy of salivary gland Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 527.2 Sialoadenitis Both 1 5 10 digestive chartreuse4 5, 1 2, 0 1, 1 1, 0 1, 0 -0.0969 1230 1 0 0.908 0.653 1.18 -1.25 965000 1 0 0.287 9.68e-09 13300000 PRS_PLINK_0.000251188643150958 527.7 Disturbance of salivary secretion Both 2 7 10 digestive chartreuse4 7, 2 2, 0 2, 1 1, 0 2, 1 0.502 75.4 0.995 0.002 1.65 0.537 6.02 0.327 5000 1 0 1.39 0.458 16.7 0.00865 1280 1 0 1.01 0.268 1.42 PRS_PLINK_0.000251188643150958 527.8 Other specified diseases of the salivary glands Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 528 Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue Both 6 34 10 digestive chartreuse4 34, 6 8, 1 8, 3 8, 2 9, 0 -0.869 0.72 0.227 0.643 0.419 0.062 1.82 -1.01 2.36 0.669 0.175 0.365 6.37e-05 18.2 -0.538 1.97 0.785 0.105 0.584 0.000124 232 -0.279 1.98 0.888 0.052 0.757 0.0258 62.9 PRS_PLINK_0.000251188643150958 528.1 Stomatitis and mucositis Both 1 9 10 digestive chartreuse4 9, 1 2, 0 2, 1 2, 0 2, 0 -0.299 16100000 1 0 0.741 5.57e-06 324 0.187 1980 1 0 1.21 0.145 2.12 PRS_PLINK_0.000251188643150958 528.11 Stomatitis and mucositis (ulcerative) Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 528.12 Oral aphthae Both 1 3 10 digestive chartreuse4 3, 1 1, 1 1, 0 1, 0 1, 1 -0.447 7820 1 0 0.64 0.265 2.49 0.0221 59.7 1 0 1.02 0.884 1.27 -0.0153 68.5 1 0 0.985 0.826 1.32 PRS_PLINK_0.000251188643150958 528.3 Cellulitis and abscess of oral soft tissues Both 0 7 10 digestive chartreuse4 7, 0 2 2 1 2 PRS_PLINK_0.000251188643150958 528.4 Cysts of oral soft tissues Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 528.5 Diseases of lips Both 1 5 10 digestive chartreuse4 5, 1 2, 0 1, 1 1, 0 1, 0 0.0158 679 1 0 1.02 0.761 1.39 -0.000104 167 1 0 1 0.912 1.22 PRS_PLINK_0.000251188643150958 528.6 Leukoplakia of oral mucosa Both 2 2 10 digestive chartreuse4 2, 2 1, 2 1, 0 1, 2 1, 0 0.0248 359 1 0 1.03 0.656 1.14 -0.0188 20.9 0.999 0 0.981 0.907 1.12 PRS_PLINK_0.000251188643150958 528.7 Sialolithiasis Both 0 1 10 digestive chartreuse4 1, 0 PRS_PLINK_0.000251188643150958 529 Diseases and other conditions of the tongue Both 1 5 10 digestive chartreuse4 5, 1 2, 1 1, 0 1, 0 1, 0 0.0471 586 1 0 1.05 0.0423 26.5 -0.436 666000 1 0 0.646 0.00136 53200 -0.146 222000 1 0 0.864 0.304 9.03e+28 -0.00746 86600 1 0 0.993 0.426 18.9 PRS_PLINK_0.000251188643150958 529.1 Glossitis Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 529.6 Glossodynia Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 530 Diseases of esophagus Both 26 36 10 digestive chartreuse4 36, 26 8, 6 9, 7 9, 8 9, 5 0.165 0.286 0.565 0.248 1.18 0.706 2.03 0.327 0.937 0.728 0.138 1.39 0.277 7.36 0.598 0.983 0.543 0.265 1.82 0.334 11.4 0.285 1.09 0.795 0.1 1.33 0.178 11 PRS_PLINK_0.000251188643150958 530.1 Esophagitis, GERD and related diseases Both 25 36 10 digestive chartreuse4 36, 25 8, 5 9, 7 9, 8 9, 5 0.232 0.296 0.434 0.362 1.26 0.747 2.23 0.608 0.998 0.542 0.266 1.84 0.344 11.6 0.806 1.02 0.428 0.369 2.24 0.39 15.5 0.423 1.11 0.702 0.153 1.53 0.202 12.6 PRS_PLINK_0.000251188643150958 530.11 GERD Both 24 36 10 digestive chartreuse4 36, 24 8, 5 9, 7 9, 8 9, 4 0.187 0.299 0.531 0.275 1.21 0.71 2.13 0.608 0.998 0.542 0.266 1.84 0.344 11.6 0.806 1.02 0.428 0.369 2.24 0.39 15.5 0.033 1.27 0.979 0.009 1.03 0.0826 10.3 PRS_PLINK_0.000251188643150958 530.13 Barrett's esophagus Both 0 10 10 digestive chartreuse4 10, 0 3 2 2 3 PRS_PLINK_0.000251188643150958 530.14 Reflux esophagitis Both 6 21 10 digestive chartreuse4 21, 6 6, 2 5, 0 5, 2 5, 2 0.186 0.919 0.84 0.076 1.2 0.143 6.52 3.21 4.13 0.436 0.36 24.9 0.064 32 1.19 1.85 0.521 0.283 3.28 0.142 2000 -0.881 2.98 0.767 0.115 0.414 0.0019 41.9 PRS_PLINK_0.000251188643150958 530.15 Eosinophilic esophagitis Both 1 5 10 digestive chartreuse4 5, 1 2, 1 1, 0 1, 0 1, 0 -0.254 1810 1 0 0.776 0.592 1.93 -0.0623 1300 1 0 0.94 0.559 1.22 -0.118 2690 1 0 0.889 0.35 1.38 -0.0548 1210 1 0 0.947 0.89 1.15 PRS_PLINK_0.000251188643150958 530.2 Esophageal bleeding (varices/hemorrhage) Both 0 6 10 digestive chartreuse4 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 530.3 Stricture and stenosis of esophagus Both 1 9 10 digestive chartreuse4 9, 1 3, 1 2, 0 2, 0 2, 0 -1.85 3.16 0.559 0.253 0.158 0.000926 12.8 -0.186 1340 1 0 0.83 0.139 2.13 0.0292 548 1 0 1.03 0.707 1.89 0.0839 1000 1 0 1.09 0.541 2.48 PRS_PLINK_0.000251188643150958 530.5 Disorders of esophageal motility Both 1 6 10 digestive chartreuse4 6, 1 2, 1 1, 0 1, 0 2, 0 0.323 1920 1 0 1.38 0.449 5.79 -6.37 72200 1 0 0.00171 1.97e-11 1.41e+08 -0.894 20900 1 0 0.409 0.022 2.01 0.36 3460 1 0 1.43 0.432 26 PRS_PLINK_0.000251188643150958 530.6 Diverticulum of esophagus, acquired Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 530.7 Gastroesophageal laceration-hemorrhage syndrome Both 2 1 10 digestive chartreuse4 1, 2 0.00653 78.5 1 0 1.01 0.952 1.04 PRS_PLINK_0.000251188643150958 530.9 Heartburn Both 2 21 10 digestive chartreuse4 21, 2 5, 1 5, 0 5, 1 5, 0 0.0929 0.994 0.926 0.034 1.1 0.0891 156 4.29 10.2 0.675 0.171 72.6 1.72e-05 3.77e+08 -0.818 4.11 0.842 0.075 0.441 0.000218 531 0.814 30.5 0.979 0.009 2.26 2.2 2.32 PRS_PLINK_0.000251188643150958 531 Peptic ulcer (excl. esophageal) Both 3 17 10 digestive chartreuse4 17, 3 5, 1 4, 1 4, 1 4, 0 0.197 0.914 0.829 0.081 1.22 0.271 27.1 -2.17 10.3 0.834 0.079 0.114 0.097 0.135 0.165 2.58 0.949 0.023 1.18 1.14 1.3 -0.566 18.8 0.976 0.011 0.568 0.0586 5.11 PRS_PLINK_0.000251188643150958 531.1 Hemorrhage from gastrointestinal ulcer Both 1 1 10 digestive chartreuse4 1, 1 0.0106 152 1 0 1.01 0.829 1.22 PRS_PLINK_0.000251188643150958 531.2 Gastric ulcer Both 3 10 10 digestive chartreuse4 10, 3 3, 2 2, 1 2, 0 3, 0 0.387 2.39 0.871 0.06 1.47 0.0436 207 0.52 4680000 1 0 1.68 0.118 21.5 0.144 1630 1 0 1.16 0.619 1.38 0.893 2100 1 0 2.44 0.142 50.5 PRS_PLINK_0.000251188643150958 531.3 Duodenal ulcer Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 531.4 Peptic ulcer, site unspecified Both 1 7 10 digestive chartreuse4 7, 1 2, 0 2, 1 1, 0 2, 0 0.724 35.6 0.984 0.007 2.06 2.18 4.26 0.0426 1500 1 0 1.04 0.635 1.86 PRS_PLINK_0.000251188643150958 531.5 Gastrojejunal ulcer Both 0 1 10 digestive chartreuse4 1, 0 PRS_PLINK_0.000251188643150958 532 Dysphagia Both 7 34 10 digestive chartreuse4 34, 7 8, 1 8, 3 8, 1 9, 2 0.121 0.481 0.801 0.096 1.13 0.444 2.86 0.732 1.27 0.565 0.248 2.08 0.262 24.4 0.809 1.76 0.645 0.19 2.25 0.0314 40800 -0.248 1.46 0.865 0.063 0.78 0.00206 10.2 PRS_PLINK_0.000251188643150958 535 Gastritis and duodenitis Both 10 31 10 digestive chartreuse4 31, 10 8, 1 8, 4 7, 3 8, 2 0.252 0.524 0.63 0.2 1.29 0.503 3.58 1.73 1.69 0.307 0.512 5.63 0.303 1430 1.68 1.73 0.33 0.481 5.39 0.371 4840 0.708 1.69 0.676 0.17 2.03 0.057 197 PRS_PLINK_0.000251188643150958 535.1 Acute gastritis Both 2 11 10 digestive chartreuse4 11, 2 3, 1 3, 0 2, 1 3, 0 0.714 1.65 0.665 0.177 2.04 1.86 2.18 -0.0288 1620 1 0 0.972 0.577 1.58 -0.343 806 1 0 0.709 0.068 10.7 0.168 26700000 1 0 1.18 0.000422 193 PRS_PLINK_0.000251188643150958 535.2 Atrophic gastritis Both 3 1 10 digestive chartreuse4 1, 3 1.05 5000 1 0 2.86 0.202 50.2 PRS_PLINK_0.000251188643150958 535.6 Duodenitis Both 1 3 10 digestive chartreuse4 3, 1 1, 0 1, 0 1, 1 1, 0 0.432 10800 1 0 1.54 0.0208 1.66 -0.0223 36.1 1 0 0.978 0.688 1.22 PRS_PLINK_0.000251188643150958 535.8 Other specified gastritis Both 2 7 10 digestive chartreuse4 7, 2 2, 0 2, 0 1, 2 2, 0 1.39 5.48 0.8 0.097 4 0.284 4.28 1.23 1830 0.999 0 3.43 0.117 170 PRS_PLINK_0.000251188643150958 535.9 Gastritis and duodenitis, NOS Both 2 15 10 digestive chartreuse4 15, 2 4, 0 4, 0 3, 0 4, 2 0.628 1.35 0.641 0.193 1.87 0.189 232 0.224 10.6 0.983 0.007 1.25 0.00568 12700 PRS_PLINK_0.000251188643150958 536 Disorders of function of stomach Both 15 30 10 digestive chartreuse4 30, 15 8, 3 7, 6 7, 1 8, 5 0.000339 0.399 0.999 0 1 0.477 2.07 1.67 1.34 0.211 0.676 5.34 0.638 115 0.0738 1.42 0.959 0.018 1.08 0.0248 18.6 0.973 1.3 0.455 0.342 2.65 0.314 45.4 PRS_PLINK_0.000251188643150958 536.3 Gastroparesis Both 6 16 10 digestive chartreuse4 16, 6 4, 1 4, 2 4, 2 4, 1 -0.494 0.74 0.504 0.298 0.61 0.099 2 0.399 3.16 0.899 0.046 1.49 0.0121 1.64 0.728 4.62 0.875 0.058 2.07 1.78 2.31 -6.86 68 0.92 0.036 0.00105 0.000728 0.00149 PRS_PLINK_0.000251188643150958 536.7 Complications of gastrostomy, colostomy and enterostomy Both 2 2 10 digestive chartreuse4 2, 2 1, 1 1, 1 1, 1 1, 1 0.0127 429 1 0 1.01 0.667 2.47 -0.0688 491 1 0 0.933 0.873 1.35 PRS_PLINK_0.000251188643150958 536.8 Dyspepsia and other specified disorders of function of stomach Both 9 25 10 digestive chartreuse4 25, 9 7, 2 6, 3 6, 0 6, 4 0.236 0.57 0.679 0.168 1.27 0.457 3.96 0.389 1.88 0.836 0.078 1.48 0.0503 66.1 -1.51 2.81 0.592 0.228 0.221 0.000213 22.9 1.81 1.6 0.257 0.59 6.13 0.503 222 PRS_PLINK_0.000251188643150958 537 Other disorders of stomach and duodenum Both 12 33 10 digestive chartreuse4 33, 12 9, 1 8, 6 8, 0 8, 5 0.271 0.381 0.476 0.322 1.31 0.686 2.65 3.92 1.94 0.0426 1.371 50.6 1.79 7.09e+08 0.155 1.49 0.917 0.038 1.17 0.0774 54.8 1.8 1.72 0.297 0.527 6.03 0.426 1530000 PRS_PLINK_0.000251188643150958 537.1 Lesions of stomach and duodenum Both 0 1 10 digestive chartreuse4 1, 0 PRS_PLINK_0.000251188643150958 539 Bariatric surgery Both 1 27 10 digestive chartreuse4 27, 1 6, 0 7, 0 6, 0 7, 1 -0.127 1.15 0.912 0.04 0.881 0.00544 143 -0.407 3.12 0.896 0.048 0.666 2.8e-05 438 PRS_PLINK_0.000251188643150958 540 Appendiceal conditions Both 0 6 10 digestive chartreuse4 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 540.1 Appendicitis Both 0 3 10 digestive chartreuse4 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 540.11 Acute appendicitis Both 0 3 10 digestive chartreuse4 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 550 Abdominal hernia Both 9 49 10 digestive chartreuse4 49, 9 12, 2 12, 1 12, 2 12, 4 -0.0647 0.404 0.873 0.059 0.937 0.382 2.02 -0.151 1.12 0.893 0.049 0.86 0.0862 9.21 1.4 1.47 0.343 0.465 4.05 0.256 105000 -0.545 1.26 0.665 0.177 0.58 0.0246 6.16 PRS_PLINK_0.000251188643150958 550.1 Inguinal hernia Both 3 20 10 digestive chartreuse4 20, 3 5, 2 5, 0 5, 0 5, 1 -0.432 0.719 0.547 0.262 0.649 0.0315 2.05 -0.389 2.96 0.896 0.048 0.678 1.24e-07 102 -0.00644 5.59 0.999 0 0.994 0.000184 5210000 -3.09 3.47 0.373 0.429 0.0454 0.000109 5.09 PRS_PLINK_0.000251188643150958 550.2 Diaphragmatic hernia Both 5 28 10 digestive chartreuse4 28, 5 7, 0 7, 1 7, 1 7, 3 0.435 0.714 0.542 0.266 1.54 0.401 8.02 1.13 1.7 0.507 0.295 3.09 0.225 276 0.56 1.85 0.763 0.118 1.75 0.0477 121 -0.328 2.3 0.887 0.052 0.721 0.000176 36500 PRS_PLINK_0.000251188643150958 550.3 Femoral hernia Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 550.4 Umbilical hernia Both 1 13 10 digestive chartreuse4 13, 1 4, 0 3, 1 3, 0 3, 0 -0.0966 1.32 0.942 0.026 0.908 0.0171 8.6 -0.000735 772 1 0 0.999 0.348 5 PRS_PLINK_0.000251188643150958 550.5 Ventral hernia Both 3 22 10 digestive chartreuse4 22, 3 6, 1 5, 0 5, 1 6, 1 -0.0691 0.915 0.94 0.027 0.933 0.0169 7.93 -1.59 3.92 0.686 0.164 0.205 0.000124 188 -0.67 2.69 0.803 0.095 0.512 0.427 28.6 -2.5 7.57 0.742 0.13 0.0824 1.98e-06 1900 PRS_PLINK_0.000251188643150958 550.6 Incisional hernia Both 0 13 10 digestive chartreuse4 13, 0 4 3 3 3 PRS_PLINK_0.000251188643150958 555 Inflammatory bowel disease and other gastroenteritis and colitis Both 5 11 10 digestive chartreuse4 11, 5 3, 0 3, 0 2, 2 3, 3 0.984 0.976 0.313 0.504 2.68 0.701 19.5 0.182 141 0.999 0 1.2 0.189 30.3 1.79 4000 1 0 5.98 8.42e-09 3.05e+10 PRS_PLINK_0.000251188643150958 555.1 Regional enteritis Both 1 9 10 digestive chartreuse4 9, 1 3, 0 2, 0 2, 0 2, 1 -0.0573 2.41 0.981 0.008 0.944 0.0323 37 0.00547 28.5 1 0 1.01 0.748 1.14 PRS_PLINK_0.000251188643150958 555.2 Ulcerative colitis Both 4 6 10 digestive chartreuse4 6, 4 2, 0 1, 1 1, 1 2, 2 0.731 32.3 0.982 0.008 2.08 0.000271 2.43 0.00335 26.8 1 0 1 0.957 1.08 0.025 1210 1 0 1.03 0.667 1.67 0.0273 38.5 0.999 0 1.03 0.00101 46200 PRS_PLINK_0.000251188643150958 555.21 Ulcerative colitis (chronic) Both 4 5 10 digestive chartreuse4 5, 4 2, 0 1, 0 1, 1 1, 3 -0.152 422 1 0 0.859 0.818 1.34 0.0441 4130 1 0 1.05 0.0251 1.31 -5.48 7.76e+08 1 0 0.00415 1.42e-37 2.18e+30 PRS_PLINK_0.000251188643150958 556 Ulceration of the lower GI tract Both 0 7 10 digestive chartreuse4 7, 0 2 2 1 2 PRS_PLINK_0.000251188643150958 556.1 Ulceration of intestine Both 0 5 10 digestive chartreuse4 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 556.11 Angiodysplasia of intestine (without mention of hemorrhage) Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 557 Intestinal malabsorption (non-celiac) Both 7 19 10 digestive chartreuse4 19, 7 5, 1 5, 1 4, 1 5, 4 0.123 0.546 0.822 0.085 1.13 0.424 2.99 -1.26 4.76 0.791 0.102 0.282 0.2 0.406 -0.732 2.33 0.754 0.123 0.481 0.00894 12.8 1.55 2.23 0.486 0.313 4.73 0.217 3710 PRS_PLINK_0.000251188643150958 557.1 Celiac disease Both 4 8 10 digestive chartreuse4 8, 4 2, 0 2, 0 2, 3 2, 1 0.0227 1.25 0.986 0.006 1.02 0.145 6.74 -0.447 1670 1 0 0.64 0.607 1.39 1.07 1150 0.999 0 2.92 0.463 3.27 PRS_PLINK_0.000251188643150958 558 Noninfectious gastroenteritis Both 11 23 10 digestive chartreuse4 23, 11 5, 1 6, 4 5, 1 6, 5 0.303 0.452 0.504 0.298 1.35 0.613 3.29 0.702 2.58 0.785 0.105 2.02 0.0264 549 -0.0504 2.21 0.982 0.008 0.951 0.00214 42.5 1.86 2.54 0.465 0.333 6.41 0.00191 1870 PRS_PLINK_0.000251188643150958 559 Ileostomy status Both 0 7 10 digestive chartreuse4 7, 0 2 2 1 2 PRS_PLINK_0.000251188643150958 560 Intestinal obstruction without mention of hernia Both 5 20 10 digestive chartreuse4 20, 5 5, 2 5, 2 5, 0 5, 1 -0.372 0.759 0.624 0.205 0.689 0.12 2.65 0.546 2.05 0.79 0.102 1.73 0.0573 64.5 -2.31 5.55 0.678 0.169 0.0995 8.9e-06 51300 1.56 4.51 0.73 0.137 4.75 0.00233 2360000 PRS_PLINK_0.000251188643150958 560.1 Paralytic ileus Both 3 9 10 digestive chartreuse4 9, 3 3, 2 2, 0 2, 1 2, 0 -1.85 3.32 0.578 0.238 0.158 0.137 18.7 0.211 2640000 1 0 1.23 0.0832 6.06 0.0543 4210 1 0 1.06 0.379 3.2 0.206 5090 1 0 1.23 0.617 7.56 PRS_PLINK_0.000251188643150958 560.2 Impaction of intestine Both 2 1 10 digestive chartreuse4 1, 2 -0.00269 105 1 0 0.997 0.941 1.11 PRS_PLINK_0.000251188643150958 560.3 Peritoneal or intestinal adhesions Both 0 1 10 digestive chartreuse4 1, 0 PRS_PLINK_0.000251188643150958 560.4 Other intestinal obstruction Both 2 13 10 digestive chartreuse4 13, 2 4, 1 3, 0 3, 1 3, 0 -0.538 1.33 0.686 0.163 0.584 0.0424 21.8 0.0484 135000 1 0 1.05 0.856 2.92 1.85 390 0.996 0.002 6.37 7.59e-06 8990000 -0.335 756 1 0 0.715 0.0322 11.9 PRS_PLINK_0.000251188643150958 561 Symptoms involving digestive system Both 7 21 10 digestive chartreuse4 21, 7 6, 0 5, 5 5, 1 5, 1 0.506 0.659 0.442 0.354 1.66 0.557 10.4 2.22 2.57 0.389 0.41 9.16 1.36 9.56 1.13 2.61 0.664 0.178 3.1 0.0378 576 -0.674 18.1 0.97 0.013 0.51 9.42e-08 2520000 PRS_PLINK_0.000251188643150958 562 Diverticulosis and diverticulitis Both 6 21 10 digestive chartreuse4 21, 6 6, 1 5, 2 5, 1 5, 2 1.38 1.15 0.231 0.636 3.98 0.214 282 2.33 2.99 0.436 0.36 10.2 0.165 22000 -0.186 2.29 0.935 0.029 0.83 0.000895 531 1.38 3.25 0.672 0.173 3.96 0.0323 575 PRS_PLINK_0.000251188643150958 562.1 Diverticulosis Both 6 21 10 digestive chartreuse4 21, 6 6, 1 5, 2 5, 1 5, 2 1.38 1.15 0.231 0.636 3.98 0.214 282 2.33 2.99 0.436 0.36 10.2 0.165 22000 -0.186 2.29 0.935 0.029 0.83 0.000895 531 1.38 3.25 0.672 0.173 3.96 0.0323 575 PRS_PLINK_0.000251188643150958 562.2 Diverticulitis Both 1 14 10 digestive chartreuse4 14, 1 4, 0 3, 1 3, 0 4, 0 -0.866 2.12 0.683 0.166 0.421 0.00083 26.4 -0.869 70.7 0.99 0.004 0.42 0.0352 0.0549 PRS_PLINK_0.000251188643150958 564 Functional digestive disorders Both 27 27 10 digestive chartreuse4 27, 27 6, 2 7, 14 6, 4 7, 7 0.148 0.343 0.666 0.177 1.16 0.632 2.2 1.69 1.18 0.152 0.818 5.42 0.79 79.9 2.48 2.6 0.341 0.467 11.9 0.17 15.2 0.769 1.51 0.611 0.214 2.16 0.178 34.9 PRS_PLINK_0.000251188643150958 564.1 Irritable Bowel Syndrome Both 5 23 10 digestive chartreuse4 23, 5 5, 0 6, 2 5, 2 6, 1 0.142 0.519 0.784 0.105 1.15 0.456 2.99 1.01 3.24 0.756 0.122 2.74 0.00924 1140000 -1.06 6.4 0.868 0.061 0.346 0.319 0.389 0.853 4.76 0.858 0.067 2.35 0.0017 10100 PRS_PLINK_0.000251188643150958 564.9 Personal history of diseases of digestive system Both 5 20 10 digestive chartreuse4 20, 5 5, 0 5, 2 5, 1 5, 2 0.751 0.82 0.36 0.444 2.12 0.605 159 0.888 2.84 0.754 0.122 2.43 0.016 7100 -0.669 4.38 0.879 0.056 0.512 0.485 0.55 2.1 2.83 0.458 0.339 8.15 0.201 9.39 PRS_PLINK_0.000251188643150958 565 Anal and rectal conditions Both 11 31 10 digestive chartreuse4 31, 11 8, 3 8, 5 7, 2 8, 1 -0.448 0.5 0.37 0.432 0.639 0.227 1.49 0.155 1.13 0.89 0.05 1.17 0.118 8.51 -1.78 1.67 0.287 0.542 0.169 0.00129 2.23 1.24 1.93 0.52 0.284 3.46 0.0037 4.09 PRS_PLINK_0.000251188643150958 565.1 Anal and rectal polyp Both 3 9 10 digestive chartreuse4 9, 3 3, 2 2, 0 2, 1 2, 0 -4.54 5.86 0.439 0.358 0.0107 1.34e-07 20.3 0.0676 1160 1 0 1.07 0.274 5.45 0.0126 276 1 0 1.01 0.932 1.52 0.0236 567 1 0 1.02 0.16 10.6 PRS_PLINK_0.000251188643150958 567 Peritonitis and retroperitoneal infections Both 1 7 10 digestive chartreuse4 7, 1 2, 0 2, 1 1, 0 2, 0 -0.582 7460 1 0 0.559 0.00115 1.32 0.103 13500 1 0 1.11 5.99e-08 1.5 PRS_PLINK_0.000251188643150958 568 Other disorders of peritoneum Both 1 12 10 digestive chartreuse4 12, 1 3, 0 3, 0 3, 0 3, 1 0.0217 0.883 0.98 0.009 1.02 0.208 8.73 -0.049 1530 1 0 0.952 0.476 1.26 PRS_PLINK_0.000251188643150958 568.1 Peritoneal adhesions (postoperative) (postinfection) Both 1 9 10 digestive chartreuse4 9, 1 3, 0 2, 0 2, 1 2, 0 0.37 1.45 0.799 0.098 1.45 1.36 1.52 -0.248 2850 1 0 0.781 0.185 1.43 PRS_PLINK_0.000251188643150958 569 Other disorders of intestine Both 18 39 10 digestive chartreuse4 39, 18 9, 4 10, 7 9, 4 10, 3 -0.167 0.356 0.639 0.195 0.846 0.411 1.6 0.491 0.942 0.602 0.22 1.63 0.311 10.1 -0.614 1.31 0.639 0.194 0.541 0.0433 4.68 -0.194 1.23 0.875 0.058 0.824 0.0206 6.3 PRS_PLINK_0.000251188643150958 569.1 Toxic gastroenteritis and colitis Both 0 3 10 digestive chartreuse4 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 569.2 Gastrointestinal complications Both 2 17 10 digestive chartreuse4 17, 2 5, 1 4, 0 4, 0 4, 1 0.338 0.84 0.688 0.163 1.4 0.159 11.8 0.938 104 0.993 0.003 2.56 2.41 2.71 0.18 2.85 0.95 0.022 1.2 0.0175 94.3 1.94 3.69 0.599 0.222 6.97 0.043 2870 PRS_PLINK_0.000251188643150958 571 Chronic liver disease and cirrhosis Both 9 33 10 digestive chartreuse4 33, 9 9, 6 8, 2 8, 0 8, 1 -0.652 0.573 0.255 0.593 0.521 0.16 1.45 -0.759 1.22 0.532 0.274 0.468 0.0422 3.38 -0.706 1.62 0.664 0.178 0.494 0.00306 7.16 0.155 1.39 0.911 0.04 1.17 0.0953 14 PRS_PLINK_0.000251188643150958 571.5 Other chronic nonalcoholic liver disease Both 9 34 10 digestive chartreuse4 34, 9 9, 6 8, 2 8, 0 9, 1 -0.63 0.576 0.274 0.562 0.533 0.159 1.49 -0.458 1.21 0.704 0.152 0.632 0.0615 4.66 -2.26 2.1 0.282 0.55 0.104 7.55e-07 3.35 -0.064 1.43 0.964 0.016 0.938 0.0554 12.1 PRS_PLINK_0.000251188643150958 571.51 Cirrhosis of liver without mention of alcohol Both 0 14 10 digestive chartreuse4 14, 0 4 3 3 4 PRS_PLINK_0.000251188643150958 571.6 Primary biliary cirrhosis Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 571.8 Liver abscess and sequelae of chronic liver disease Both 1 12 10 digestive chartreuse4 12, 1 3, 1 3, 0 3, 0 3, 0 -0.0368 1.23 0.976 0.01 0.964 0.071 18.2 0.221 877 1 0 1.25 0.683 4.03 0.351 166 0.998 0.001 1.42 0.353 9.48 -0.0827 385 1 0 0.921 0.215 3.73 PRS_PLINK_0.000251188643150958 571.81 Portal hypertension Both 1 8 10 digestive chartreuse4 8, 1 2, 1 2, 0 2, 0 2, 0 6.13e-13 8.87 1 0 1 0.349 0.987 0.374 2140 1 0 1.45 0.67 1.57 -0.355 4740000 1 0 0.701 0.0933 207 0.297 401 0.999 0 1.35 0.811 1.63 PRS_PLINK_0.000251188643150958 572 Ascites (non malignant) Both 1 23 10 digestive chartreuse4 23, 1 6, 0 6, 1 5, 0 6, 0 -0.258 0.779 0.741 0.13 0.773 0.0611 3.55 1.23 2.13 0.563 0.25 3.44 0.0753 1340 PRS_PLINK_0.000251188643150958 573 Other disorders of liver Both 7 38 10 digestive chartreuse4 38, 7 9, 3 9, 2 9, 1 10, 1 -0.201 0.515 0.696 0.158 0.818 0.298 2.17 0.564 1.32 0.669 0.174 1.76 0.186 20.7 -0.576 1.42 0.684 0.165 0.562 0.0294 6.44 -0.0346 1.43 0.981 0.008 0.966 0.0345 365 PRS_PLINK_0.000251188643150958 573.1 Chronic passive congestion of liver Both 0 2 10 digestive chartreuse4 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 573.2 Liver replaced by transplant Both 0 6 10 digestive chartreuse4 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 573.3 Hepatomegaly Both 1 5 10 digestive chartreuse4 5, 1 2, 1 1, 0 1, 0 1, 0 0.671 1310 1 0 1.96 0.459 15.3 0.00253 55.7 1 0 1 0.924 1.07 -0.186 10600000 1 0 0.831 0.00558 202 0.00231 44.1 1 0 1 0.929 1.08 PRS_PLINK_0.000251188643150958 573.4 Acute and subacute necrosis of liver Both 0 3 10 digestive chartreuse4 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 573.5 Jaundice (not of newborn) Both 2 13 10 digestive chartreuse4 13, 2 4, 1 3, 1 3, 0 3, 0 -0.19 0.986 0.848 0.072 0.827 0.0949 6.21 4.77 52.3 0.927 0.033 118 768 603 0.204 4860 1 0 1.23 0.317 1.44 1.72 2760 1 0 5.58 34.3 320 PRS_PLINK_0.000251188643150958 573.6 Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH] Both 7 31 10 digestive chartreuse4 31, 7 8, 3 8, 2 7, 1 8, 1 -0.689 0.67 0.303 0.518 0.502 0.12 1.6 -0.557 1.34 0.678 0.169 0.573 0.000927 5.38 0.0344 1.58 0.983 0.008 1.04 0.0629 13.4 -1.2 1.98 0.545 0.264 0.301 0.00556 4.41 PRS_PLINK_0.000251188643150958 573.7 Abnormal results of function study of liver Both 7 30 10 digestive chartreuse4 30, 7 8, 2 7, 2 7, 2 8, 1 0.0408 0.534 0.939 0.027 1.04 0.363 2.71 1.13 1.89 0.547 0.262 3.11 0.145 514 1.74 2.22 0.432 0.365 5.71 0.146 394 0.517 1.55 0.739 0.132 1.68 0.0732 52.7 PRS_PLINK_0.000251188643150958 573.9 Abnormal serum enzyme levels Both 13 39 10 digestive chartreuse4 39, 13 9, 5 10, 4 9, 3 10, 1 -0.612 0.465 0.188 0.725 0.542 0.211 1.24 -0.615 1.12 0.584 0.233 0.541 0.0133 3.95 -0.773 1.2 0.518 0.286 0.462 0.0472 3.24 -0.9 1.14 0.428 0.368 0.406 0.0285 3.67 PRS_PLINK_0.000251188643150958 574 Cholelithiasis and cholecystitis Both 1 45 10 digestive chartreuse4 45, 1 12, 0 11, 0 11, 0 11, 1 0.619 0.748 0.408 0.389 1.86 0.367 193 0.879 1.46 0.548 0.261 2.41 0.0874 1400 PRS_PLINK_0.000251188643150958 574.1 Cholelithiasis Both 1 43 10 digestive chartreuse4 43, 1 11, 0 11, 0 10, 0 11, 1 0.572 0.762 0.453 0.344 1.77 0.35 22 0.694 1.63 0.671 0.173 2 0.0358 38700 PRS_PLINK_0.000251188643150958 574.11 Cholelithiasis with acute cholecystitis Both 0 6 10 digestive chartreuse4 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 574.12 Cholelithiasis with other cholecystitis Both 0 14 10 digestive chartreuse4 14, 0 4 3 3 4 PRS_PLINK_0.000251188643150958 574.2 Calculus of bile duct Both 0 11 10 digestive chartreuse4 11, 0 3 3 2 3 PRS_PLINK_0.000251188643150958 574.3 Cholecystitis without cholelithiasis Both 0 14 10 digestive chartreuse4 14, 0 4 3 3 4 PRS_PLINK_0.000251188643150958 575 Other biliary tract disease Both 0 33 10 digestive chartreuse4 33, 0 9 8 8 8 PRS_PLINK_0.000251188643150958 575.1 Cholangitis Both 0 1 10 digestive chartreuse4 1, 0 PRS_PLINK_0.000251188643150958 575.2 Obstruction of bile duct Both 0 5 10 digestive chartreuse4 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 575.6 Cholesterolosis of gallbladder Both 0 5 10 digestive chartreuse4 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 575.7 Other disorders of gallbladder Both 0 12 10 digestive chartreuse4 12, 0 3 3 3 3 PRS_PLINK_0.000251188643150958 575.8 Other disorders of biliary tract Both 0 12 10 digestive chartreuse4 12, 0 3 3 3 3 PRS_PLINK_0.000251188643150958 577 Diseases of pancreas Both 3 31 10 digestive chartreuse4 31, 3 8, 2 8, 1 7, 0 8, 0 -0.799 0.836 0.339 0.47 0.45 0.0422 5.08 0.55 1.43 0.7 0.155 1.73 0.163 163 0.608 2.64 0.818 0.087 1.84 0.00285 29600 -0.72 1.96 0.713 0.147 0.487 2.25e-05 96.7 PRS_PLINK_0.000251188643150958 577.1 Acute pancreatitis Both 1 19 10 digestive chartreuse4 19, 1 5, 0 5, 1 4, 0 5, 0 -0.465 0.846 0.583 0.235 0.628 0.0268 2.91 -0.418 117 0.997 0.001 0.659 0.129 0.545 PRS_PLINK_0.000251188643150958 577.2 Chronic pancreatitis Both 0 3 10 digestive chartreuse4 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 577.3 Cyst and pseudocyst of pancreas Both 0 4 10 digestive chartreuse4 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 578 Gastrointestinal hemorrhage Both 13 46 10 digestive chartreuse4 46, 13 11, 2 11, 5 11, 3 12, 3 0.05 0.336 0.882 0.055 1.05 0.546 1.96 0.986 0.994 0.321 0.493 2.68 0.486 21 1.07 1.47 0.468 0.33 2.91 0.19 226 -0.0969 1.14 0.932 0.031 0.908 0.0723 40.6 PRS_PLINK_0.000251188643150958 578.1 Hematemesis Both 4 5 10 digestive chartreuse4 5, 4 2, 2 1, 1 1, 1 1, 0 -0.0207 76.8 1 0 0.98 0.743 1.27 0.105 393 1 0 1.11 0.845 2.44 0.911 10100 1 0 2.49 0.00389 1.28e+09 -0.132 3570 1 0 0.876 0.736 1.56 PRS_PLINK_0.000251188643150958 578.2 Blood in stool Both 7 33 10 digestive chartreuse4 33, 7 9, 0 8, 3 8, 3 8, 1 0.0383 0.543 0.944 0.025 1.04 0.392 2.98 2.23 2.01 0.267 0.573 9.32 0.465 4790000 1.26 1.84 0.492 0.308 3.53 0.101 631 0.642 1.83 0.726 0.139 1.9 0.0735 139 PRS_PLINK_0.000251188643150958 578.8 Hemorrhage of rectum and anus Both 7 31 10 digestive chartreuse4 31, 7 8, 1 8, 2 7, 3 8, 1 0.0198 0.571 0.972 0.012 1.02 0.361 3.15 0.583 1.39 0.675 0.171 1.79 0.111 36.8 -0.428 1.62 0.792 0.101 0.652 0.0198 10.7 0.0767 2.15 0.971 0.013 1.08 0.00912 51.2 PRS_PLINK_0.000251188643150958 578.9 Hemorrhage of gastrointestinal tract Both 3 16 10 digestive chartreuse4 16, 3 4, 1 4, 0 4, 1 4, 1 -0.461 0.872 0.597 0.224 0.631 0.0917 3.44 0.211 1780 1 0 1.24 0.359 0.791 1.26 5.98 0.834 0.079 3.51 0.742 3.72 -0.859 31 0.978 0.01 0.424 0.11 0.858 PRS_PLINK_0.000251188643150958 579 Other symptoms involving abdomen and pelvis Both 6 41 10 digestive chartreuse4 41, 6 10, 3 10, 3 10, 0 10, 0 -0.594 0.464 0.2 0.698 0.552 0.181 1.31 0.0969 1.04 0.926 0.033 1.1 0.155 6.94 -1.22 1.65 0.46 0.337 0.295 0.00077 26 -1.45 1.4 0.299 0.524 0.233 0.00486 2.43 PRS_PLINK_0.000251188643150958 579.2 Splenomegaly Both 1 9 10 digestive chartreuse4 9, 1 3, 1 2, 0 2, 0 2, 0 -0.0138 1.61 0.993 0.003 0.986 0.0835 11.1 0.0543 4290 1 0 1.06 0.00831 52.2 0.351 2350 1 0 1.42 0.737 1.8 0.179 2560 1 0 1.2 0.773 1.34 PRS_PLINK_0.000251188643150958 579.8 Nonspecific abnormal findings in stool contents Both 2 19 10 digestive chartreuse4 19, 2 5, 0 5, 1 4, 1 5, 0 0.0619 1.09 0.955 0.02 1.06 0.0278 58.5 0.489 8.56 0.954 0.02 1.63 1.32e-05 254000 -0.863 8.76 0.922 0.035 0.422 2.72e-06 77400 PRS_PLINK_0.000251188643150958 580 Nephritis; nephrosis; renal sclerosis Both 15 11 11 genitourinary black 11, 15 3, 4 3, 8 2, 1 3, 2 -0.934 0.807 0.247 0.607 0.393 0.0604 1.4 1.41 1.48 0.343 0.465 4.09 0.402 298 3.88 42.7 0.928 0.033 48.4 37.6 61.9 0.000597 2.39 1 0 1 0.0252 1.78 PRS_PLINK_0.000251188643150958 580.1 Glomerulonephritis Both 2 4 11 genitourinary black 4, 2 1, 0 1, 2 1, 0 1, 0 0.23 6390 1 0 1.26 0.13 6.79 15.7 1.69e+09 1 0 6860000 1.06e-14 1.19e+38 PRS_PLINK_0.000251188643150958 580.11 Proliferative glomerulonephritis Both 1 1 11 genitourinary black 1, 1 -0.00136 136 1 0 0.999 0.978 3.06 PRS_PLINK_0.000251188643150958 580.12 Non-proliferative glomerulonephritis Both 0 1 11 genitourinary black 1, 0 PRS_PLINK_0.000251188643150958 580.13 Acute glomerulonephritis, NOS Both 1 1 11 genitourinary black 1, 1 0.0144 94.9 1 0 1.01 0.835 1.27 PRS_PLINK_0.000251188643150958 580.14 Chronic glomerulonephritis, NOS Both 0 2 11 genitourinary black 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 580.2 Nephrotic syndrome without mention of glomerulonephritis Both 0 3 11 genitourinary black 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 580.3 Nephritis and nephropathy without mention of glomerulonephritis Both 13 11 11 genitourinary black 11, 13 3, 4 3, 6 2, 1 3, 2 -0.929 0.815 0.255 0.594 0.395 0.0483 1.4 1.27 1.57 0.418 0.378 3.56 0.361 10.2 3.88 42.7 0.928 0.033 48.4 37.6 61.9 0.000597 2.39 1 0 1 0.0252 1.78 PRS_PLINK_0.000251188643150958 580.31 Nephritis and nephropathy in diseases classified elsewhere Both 11 9 11 genitourinary black 9, 11 3, 5 2, 4 2, 1 2, 1 -1.23 0.983 0.211 0.675 0.293 0.0112 1.26 0.407 2.04 0.842 0.075 1.5 0.0155 300 -2.81 17.9 0.876 0.058 0.0605 9.51e-10 4910000 0.0501 2.79 0.986 0.006 1.05 0.964 1.08 PRS_PLINK_0.000251188643150958 580.32 Nephritis and nephropathy with pathological lesion Both 3 7 11 genitourinary black 7, 3 2, 1 2, 1 1, 0 2, 1 0.388 2.71 0.886 0.052 1.47 1.35 1.58 0.076 1870 1 0 1.08 0.709 1.1 0.0293 3740 1 0 1.03 0.621 1.05 -0.0442 3230 1 0 0.957 0.349 2.32 PRS_PLINK_0.000251188643150958 580.4 Renal sclerosis, NOS Both 1 3 11 genitourinary black 3, 1 1, 1 1, 0 1, 0 1, 1 0.351 10500 1 0 1.42 0.0147 175 7.05 20100 1 0 1150 8.9e-07 1.57e+14 5.42 7.55e+08 1 0 226 9.27e-07 9.33e+10 PRS_PLINK_0.000251188643150958 585 Renal failure Both 24 16 11 genitourinary black 16, 24 4, 3 4, 2 4, 11 4, 7 0.103 0.519 0.842 0.074 1.11 0.406 3.09 1.18 1.81 0.514 0.289 3.26 0.258 209 1.03 1.36 0.449 0.348 2.79 0.314 348 -0.434 1.77 0.806 0.094 0.648 0.00241 35.9 PRS_PLINK_0.000251188643150958 585.1 Acute renal failure Both 8 14 11 genitourinary black 14, 8 4, 2 3, 1 3, 4 4, 1 0.229 0.745 0.758 0.12 1.26 0.353 4.53 -0.67 2.99 0.823 0.085 0.512 0.477 0.624 1.12 1.64 0.494 0.306 3.07 0.458 3.51 -1.19 2.73 0.663 0.179 0.304 2.49e-05 232 PRS_PLINK_0.000251188643150958 585.2 Renal failure NOS Both 4 6 11 genitourinary black 6, 4 2, 0 1, 4 1, 0 2, 0 0.741 3.33 0.824 0.084 2.1 0.0111 2.37 -0.012 1550 1 0 0.988 0.648 1.48 PRS_PLINK_0.000251188643150958 585.3 Chronic renal failure [CKD] Both 17 15 11 genitourinary black 15, 17 4, 2 4, 1 3, 8 4, 5 0.485 0.681 0.477 0.322 1.62 0.412 6.76 1.06 2.54 0.677 0.169 2.88 0.131 189 0.847 1.67 0.611 0.214 2.33 0.0733 13200 0.633 1.81 0.726 0.139 1.88 0.0455 118 PRS_PLINK_0.000251188643150958 585.31 Renal dialysis Both 0 5 11 genitourinary black 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 585.32 End stage renal disease Both 1 9 11 genitourinary black 9, 1 3, 0 2, 0 2, 0 2, 0 0.074 1.45 0.959 0.018 1.08 0.0862 37.5 PRS_PLINK_0.000251188643150958 585.33 Chronic Kidney Disease, Stage III Both 7 11 11 genitourinary black 11, 7 3, 0 3, 1 2, 4 3, 2 -0.214 1.3 0.87 0.061 0.808 0.000355 38.1 0.117 1770 1 0 1.12 0.599 1.33 0.531 222 0.998 0.001 1.7 11.9 6.93 0.131 6020000 1 0 1.14 0.371 2.06 PRS_PLINK_0.000251188643150958 585.34 Chronic Kidney Disease, Stage IV Both 0 10 11 genitourinary black 10, 0 3 2 2 3 PRS_PLINK_0.000251188643150958 585.4 Chronic kidney disease, Stage I or II Both 10 10 11 genitourinary black 10, 10 3, 1 2, 1 2, 4 3, 4 0.369 1.14 0.745 0.128 1.45 0.216 70.4 0.0864 2380000 1 0 1.09 0.513 2.48 -0.256 13.9 0.985 0.006 0.774 0.719 0.846 0.833 1.88 0.658 0.182 2.3 0.16 41 PRS_PLINK_0.000251188643150958 586 Other disorders of the kidney and ureters Both 37 17 11 genitourinary black 17, 37 5, 8 4, 6 4, 16 4, 7 -0.412 0.371 0.268 0.572 0.662 0.318 1.31 0.167 1.32 0.9 0.046 1.18 0.131 12.2 0.501 0.965 0.604 0.219 1.65 0.291 9.88 -0.385 1.15 0.737 0.132 0.68 0.089 4.84 PRS_PLINK_0.000251188643150958 586.1 Anatomical abnormatilies of kidney and ureters Both 2 2 11 genitourinary black 2, 2 1, 1 1, 1 1, 1 1, 1 -0.0754 833 1 0 0.927 0.347 1.42 -0.0613 277 1 0 0.941 0.655 1.1 PRS_PLINK_0.000251188643150958 586.11 Small kidney Both 1 0 11 genitourinary black 0, 1 PRS_PLINK_0.000251188643150958 586.12 Vesicoureteral reflux Both 2 1 11 genitourinary black 1, 2 -0.121 1520 1 0 0.886 0.816 1.09 PRS_PLINK_0.000251188643150958 586.2 Cyst of kidney, acquired Both 2 6 11 genitourinary black 6, 2 2, 0 1, 2 1, 0 2, 0 0.373 1e+07 1 0 1.45 0.514 184 -0.357 4800 1 0 0.7 0.452 1.52 PRS_PLINK_0.000251188643150958 586.3 Vascular disorders of kidney/hypertrophy Both 0 1 11 genitourinary black 1, 0 PRS_PLINK_0.000251188643150958 586.4 Stricture/obstruction of ureter Both 3 6 11 genitourinary black 6, 3 2, 0 1, 0 1, 1 2, 2 0.619 10 0.951 0.022 1.86 1.83 4.98 -0.781 19300 1 0 0.458 0.402 78 -0.792 5720 1 0 0.453 0.427 1.35 PRS_PLINK_0.000251188643150958 587 Kidney replaced by transpant Both 1 8 11 genitourinary black 8, 1 2, 0 2, 1 2, 0 2, 0 0.0386 116 1 0 1.04 0.329 3.02 -0.0334 2060 1 0 0.967 0.924 1.69 PRS_PLINK_0.000251188643150958 588 Disorders resulting from impaired renal function Both 2 10 11 genitourinary black 10, 2 3, 0 2, 1 2, 0 3, 1 -0.238 1.8 0.895 0.048 0.788 0.767 0.812 0.0869 1430 1 0 1.09 0.802 2.74 -0.138 619000 1 0 0.871 0.259 2.66 PRS_PLINK_0.000251188643150958 588.1 Renal osteodystrophy Both 0 5 11 genitourinary black 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 588.2 Secondary hyperparathyroidism (of renal origin) Both 2 8 11 genitourinary black 8, 2 2, 0 2, 1 2, 0 2, 1 -0.0811 2.23 0.971 0.013 0.922 0.915 0.932 0.117 2450 1 0 1.12 0.694 1.2 0.116 8240 1 0 1.12 0.413 3.37 PRS_PLINK_0.000251188643150958 589 Abnormal results of function study of kidney Both 5 8 11 genitourinary black 8, 5 2, 0 2, 1 2, 3 2, 1 -0.543 1.79 0.761 0.119 0.581 0.0318 7.82 0.0318 2.9e+08 1 0 1.03 0.000469 15900 -0.189 2580 1 0 0.828 0.162 1.46 -1.78 6150 1 0 0.168 1.61e-09 7540 PRS_PLINK_0.000251188643150958 590 Pyelonephritis Both 4 8 11 genitourinary black 8, 4 2, 1 2, 2 2, 1 2, 0 1.69 3.53 0.633 0.198 5.4 0.0481 6350 0.27 2080 1 0 1.31 1.25 2.78 -0.177 639 1 0 0.838 0.198 4 0.0794 1720 1 0 1.08 0.778 1.66 PRS_PLINK_0.000251188643150958 591 Urinary tract infection Both 25 31 11 genitourinary black 31, 25 7, 4 8, 5 7, 5 8, 11 0.397 0.336 0.237 0.625 1.49 0.814 2.82 0.883 1.28 0.491 0.309 2.42 0.299 46.9 -1.31 1.45 0.367 0.436 0.271 0.00527 3.56 -0.0715 1.13 0.95 0.022 0.931 0.108 6.89 PRS_PLINK_0.000251188643150958 592 Cystitis and urethritis Both 9 15 11 genitourinary black 15, 9 3, 0 4, 3 3, 1 4, 5 0.332 0.749 0.657 0.182 1.39 0.404 7.52 -0.103 3.76 0.978 0.01 0.902 0.877 0.955 0.378 17100000 1 0 1.46 0.658 43.5 0.224 3.31 0.946 0.024 1.25 0.00802 197 PRS_PLINK_0.000251188643150958 592.1 Cystitis Both 9 14 11 genitourinary black 14, 9 3, 0 3, 3 3, 1 4, 5 0.626 0.877 0.475 0.323 1.87 0.459 70.3 -0.769 113 0.995 0.002 0.463 0.714 0.811 0.0801 359 1 0 1.08 0.691 1.25 0.139 2.27 0.951 0.022 1.15 0.0115 41.5 PRS_PLINK_0.000251188643150958 592.11 Acute cystitis Both 6 10 11 genitourinary black 10, 6 2, 0 2, 2 2, 1 3, 3 -0.159 1.26 0.9 0.046 0.853 0.102 7.51 1.41 4690 1 0 4.1 0.454 5.96 -0.947 4200 1 0 0.388 0.369 1.21 -0.102 1070000 1 0 0.903 0.629 2.41 PRS_PLINK_0.000251188643150958 592.12 Chronic cystitis Both 2 3 11 genitourinary black 3, 2 1, 0 1, 0 1, 2 1, 0 0.298 2960000 1 0 1.35 0.416 2.42 0.127 3440 1 0 1.14 0.535 1.4 PRS_PLINK_0.000251188643150958 592.13 Chronic interstitial cystitis Both 1 7 11 genitourinary black 7, 1 2, 0 2, 1 1, 0 2, 0 -0.0744 916 1 0 0.928 0.481 1.22 -0.0164 3660 1 0 0.984 0.437 1.69 PRS_PLINK_0.000251188643150958 592.2 Urethritis and urethral syndrome Both 2 1 11 genitourinary black 1, 2 -0.186 18.1 0.992 0.004 0.83 0.729 1.92 PRS_PLINK_0.000251188643150958 593 Hematuria Both 17 29 11 genitourinary black 29, 17 7, 2 7, 5 7, 4 7, 6 0.695 0.403 0.0846 1.073 2 1.03 4.78 2.62 2.25 0.244 0.612 13.7 0.599 714000 -0.591 1.5 0.694 0.158 0.554 0.0248 8 0.708 1.55 0.648 0.188 2.03 0.125 169 PRS_PLINK_0.000251188643150958 593.1 Gross hematuria Both 6 16 11 genitourinary black 16, 6 4, 0 4, 4 4, 0 4, 2 1.27 0.816 0.121 0.917 3.54 1.05 254 2.07 10 0.837 0.077 7.9 7.22 8.76 -2.92 33.7 0.931 0.031 0.0537 0.0427 0.0678 PRS_PLINK_0.000251188643150958 593.2 Microscopic hematuria Both 6 9 11 genitourinary black 9, 6 3, 0 2, 1 2, 2 2, 3 -0.323 1.98 0.87 0.06 0.724 0.01 37.4 -0.218 266 0.999 0 0.804 0.347 2.04 0.0848 2050 1 0 1.09 0.698 1.23 0.122 338 1 0 1.13 0.655 2.22 PRS_PLINK_0.000251188643150958 594 Urinary calculus Both 13 43 11 genitourinary black 43, 13 10, 2 11, 3 10, 3 11, 5 0.158 0.448 0.724 0.141 1.17 0.493 2.82 0.223 1.09 0.838 0.077 1.25 0.16 9.94 -0.199 1.16 0.864 0.064 0.819 0.0767 10.4 0.313 1.37 0.819 0.087 1.37 0.0465 16 PRS_PLINK_0.000251188643150958 594.1 Calculus of kidney Both 13 43 11 genitourinary black 43, 13 10, 2 11, 3 10, 3 11, 5 0.158 0.448 0.724 0.141 1.17 0.493 2.82 0.223 1.09 0.838 0.077 1.25 0.16 9.94 -0.199 1.16 0.864 0.064 0.819 0.0767 10.4 0.313 1.37 0.819 0.087 1.37 0.0465 16 PRS_PLINK_0.000251188643150958 594.2 Calculus of lower urinary tract Both 1 4 11 genitourinary black 4, 1 1, 0 1, 1 1, 0 1, 0 1.25 426 0.998 0.001 3.51 0.00873 268000 -3.39 9810 1 0 0.0337 4.51e-10 184000 PRS_PLINK_0.000251188643150958 594.3 Calculus of ureter Both 2 17 11 genitourinary black 17, 2 4, 1 4, 0 4, 1 4, 0 0.454 0.75 0.545 0.264 1.57 0.112 8.21 -0.389 6.05 0.949 0.023 0.677 0.301 0.331 0.61 9.16 0.947 0.024 1.84 1.54 2.27 -1.48 82 0.986 0.006 0.227 0.141 0.373 PRS_PLINK_0.000251188643150958 594.8 Renal colic Both 1 5 11 genitourinary black 5, 1 2, 1 1, 0 1, 0 1, 0 -0.0532 597 1 0 0.948 0.492 1.35 0.181 4180 1 0 1.2 0.634 1.28 0.00488 20.1 1 0 1 0.903 1.08 -0.232 1480 1 0 0.793 0.109 1.78 PRS_PLINK_0.000251188643150958 595 Hydronephrosis Both 4 15 11 genitourinary black 15, 4 4, 1 4, 1 3, 1 4, 1 0.763 1.09 0.485 0.315 2.14 0.182 24.4 0.138 2.14 0.948 0.023 1.15 0.0506 32.2 1.86 210 0.993 0.003 6.4 0.089 139 1.99 14 0.886 0.052 7.34 0.506 7.67 PRS_PLINK_0.000251188643150958 596 Other disorders of bladder Both 5 25 11 genitourinary black 25, 5 6, 3 6, 1 6, 0 6, 1 0.749 0.971 0.441 0.356 2.11 0.4 104 -0.426 1.78 0.811 0.091 0.653 0.00195 12.7 -2.78 4.19 0.506 0.296 0.0619 1.95e-09 17.9 -0.0911 2.67 0.973 0.012 0.913 0.00618 381000 PRS_PLINK_0.000251188643150958 596.1 Bladder neck obstruction Both 1 2 11 genitourinary black 2, 1 1, 1 1, 0 1, 1 1, 0 38.4 2.18e+10 1 0 4.93e+16 2.15e-67 1.15e+79 0.0567 18100 1 0 1.06 0.114 151 PRS_PLINK_0.000251188643150958 596.5 Functional disorders of bladder Both 5 16 11 genitourinary black 16, 5 4, 4 4, 0 4, 1 4, 0 0.784 1.16 0.5 0.301 2.19 0.286 1060 -5.1 8.11 0.53 0.276 0.00611 1.23e-10 789 -1.92 2.92 0.509 0.293 0.146 0.00271 12 -0.823 2.48 0.74 0.131 0.439 0.00781 27.5 PRS_PLINK_0.000251188643150958 597 Other disorders of urethra and urinary tract Both 3 7 11 genitourinary black 7, 3 2, 2 2, 0 1, 0 2, 1 0.0675 2.42 0.978 0.01 1.07 0.0263 35.3 -0.551 4090 1 0 0.576 0.561 2.06 0.00476 43.7 1 0 1 0.936 1.24 -0.427 1670 1 0 0.652 0.042 1.86 PRS_PLINK_0.000251188643150958 597.1 Urethral stricture (not specified as infectious) Both 2 2 11 genitourinary black 2, 2 1, 1 1, 1 1, 1 1, 1 -0.0853 1730 1 0 0.918 0.39 1.27 -0.123 2180 1 0 0.885 0.328 1.36 PRS_PLINK_0.000251188643150958 597.2 Urinary complications NEC Both 1 8 11 genitourinary black 8, 1 2, 0 2, 0 2, 0 2, 1 0.0914 6.16 0.988 0.005 1.1 0.525 2.48 3.06 7630 1 0 21.2 9.3e-05 12100000 PRS_PLINK_0.000251188643150958 597.8 Urethral hypermobility/ISD Both 0 2 11 genitourinary black 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 598 Abnormal findings on examination of urine Both 0 2 11 genitourinary black 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 598.4 Other cells and casts in urine Both 0 2 11 genitourinary black 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 599 Other symptoms/disorders or the urinary system Both 25 35 11 genitourinary black 35, 25 8, 1 9, 9 8, 4 9, 11 0.586 0.325 0.0713 1.147 1.8 1.02 3.44 2.43 1.58 0.123 0.91 11.4 0.918 2190 0.378 1.48 0.798 0.098 1.46 0.0313 39.1 1.32 1.33 0.322 0.492 3.74 0.379 146 PRS_PLINK_0.000251188643150958 599.1 Urinary obstruction Both 3 6 11 genitourinary black 6, 3 2, 1 1, 0 1, 0 2, 2 0.865 3700000 1 0 2.37 0.131 34.5 -0.255 16900 1 0 0.775 0.048 3.07 0.172 19500 1 0 1.19 0.593 1.46 0.194 311 1 0 1.21 0.068 102 PRS_PLINK_0.000251188643150958 599.2 Retention of urine Both 11 27 11 genitourinary black 27, 11 6, 0 7, 5 6, 2 7, 4 0.379 0.46 0.41 0.388 1.46 0.701 4.09 1.2 2.05 0.557 0.254 3.33 0.102 6370 1.79 2.89 0.537 0.27 5.97 0.000847 6270 1.83 2.39 0.443 0.353 6.25 0.102 3590 PRS_PLINK_0.000251188643150958 599.3 Dysuria Both 13 27 11 genitourinary black 27, 13 6, 0 7, 5 6, 2 7, 6 0.718 0.466 0.123 0.91 2.05 0.956 5.44 1.01 2.57 0.693 0.159 2.75 0.0137 4230 -0.438 2.84 0.877 0.057 0.645 0.000986 157 2.61 2.49 0.294 0.532 13.6 0.255 2.92e+08 PRS_PLINK_0.000251188643150958 599.4 Urinary incontinence Both 6 24 11 genitourinary black 24, 6 5, 0 6, 4 6, 1 6, 1 -0.309 0.868 0.722 0.142 0.734 0.1 5.98 2 2.62 0.446 0.351 7.36 0.112 9570 -0.243 2.74 0.929 0.032 0.785 0.00185 1220 -0.75 2.92 0.797 0.098 0.473 3.44e-05 57.8 PRS_PLINK_0.000251188643150958 599.5 Frequency of urination and polyuria Both 10 31 11 genitourinary black 31, 10 7, 0 8, 5 7, 1 8, 4 0.729 0.554 0.188 0.726 2.07 0.793 7.48 1.75 2.04 0.392 0.406 5.73 0.214 15300000 0.725 1.94 0.709 0.149 2.07 0.00486 299 1.38 2.02 0.493 0.308 3.99 0.0317 4130 PRS_PLINK_0.000251188643150958 599.6 Oliguria and anuria Both 1 10 11 genitourinary black 10, 1 3, 1 2, 0 2, 0 3, 0 0.257 1.8 0.886 0.053 1.29 0.0121 22.8 -0.000337 445 1 0 1 0.834 1.23 0.117 841 1 0 1.12 0.71 1.15 0.0286 106 1 0 1.03 0.775 1.23 PRS_PLINK_0.000251188643150958 599.7 Urethral discharge Both 0 6 11 genitourinary black 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 599.8 Other symptoms involving urinary system Both 12 28 11 genitourinary black 28, 12 6, 1 7, 4 7, 0 7, 7 0.368 0.52 0.479 0.32 1.45 0.584 4.46 0.88 1.89 0.641 0.193 2.41 0.1 4880 -0.816 2.63 0.757 0.121 0.442 0.000139 48.2 1.58 1.82 0.387 0.412 4.84 0.231 3410 PRS_PLINK_0.000251188643150958 599.9 Other abnormality of urination Both 5 21 11 genitourinary black 21, 5 6, 0 5, 2 5, 0 5, 3 1.5 0.891 0.0931 1.031 4.47 1.11 82.8 1.87 3.15 0.553 0.257 6.5 0.062 10100 1.71 2.31 0.457 0.34 5.55 0.237 2420 PRS_PLINK_0.000251188643150958 600 Hyperplasia of prostate Male 3 16 11 genitourinary black 16, 3 4, 2 4, 0 4, 0 4, 1 0.751 1.48 0.613 0.213 2.12 0.0189 828 -3.21 59.4 0.957 0.019 0.0405 0.033 0.0498 3.13 10 0.755 0.122 22.8 17.3 29.2 2.48 3.58 0.488 0.311 12 0.0423 23.8 PRS_PLINK_0.000251188643150958 601 Inflammatory diseases of prostate Male 3 13 11 genitourinary black 13, 3 4, 0 3, 0 3, 1 3, 2 0.325 0.902 0.719 0.143 1.38 0.108 10.7 -0.023 1300 1 0 0.977 0.628 2.29 0.236 32.4 0.994 0.003 1.27 0.188 7.25 PRS_PLINK_0.000251188643150958 601.1 Prostatitis Male 3 5 11 genitourinary black 5, 3 2, 0 1, 0 1, 0 1, 3 0.755 2210000 1 0 2.13 0.874 8.09 0.186 532 1 0 1.2 0.716 2.23 PRS_PLINK_0.000251188643150958 601.11 Acute prostatitis Male 1 1 11 genitourinary black 1, 1 -0.00072 11.3 1 0 0.999 0.0252 1.02 PRS_PLINK_0.000251188643150958 601.12 Chronic prostatitis Male 0 1 11 genitourinary black 1, 0 PRS_PLINK_0.000251188643150958 601.3 Orchitis and epididymitis Male 0 4 11 genitourinary black 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 601.4 Balanoposthitis Male 0 3 11 genitourinary black 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 602 Other disorders of prostate Male 1 3 11 genitourinary black 3, 1 1, 1 1, 0 1, 0 1, 1 -0.0645 856 1 0 0.938 0.664 1.23 -0.204 6020 1 0 0.815 0.000863 545 1.23 4.58e+08 1 0 3.41 0.000152 4440 PRS_PLINK_0.000251188643150958 602.3 Dysplasia of prostate Male 0 1 11 genitourinary black 1, 0 PRS_PLINK_0.000251188643150958 603 Other disorders of testis Male 0 7 11 genitourinary black 7, 0 2 2 1 2 PRS_PLINK_0.000251188643150958 603.1 Hydrocele Male 0 4 11 genitourinary black 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 603.2 Spermatocele Male 0 5 11 genitourinary black 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 604 Disorders of penis Male 2 6 11 genitourinary black 6, 2 2, 0 1, 2 1, 0 2, 0 0.228 77.2 0.998 0.001 1.26 2.19 2.55 -0.0161 202 1 0 0.984 0.872 1.09 PRS_PLINK_0.000251188643150958 604.3 Peyronie's disease Male 1 1 11 genitourinary black 1, 1 0.0106 152 1 0 1.01 0.829 1.22 PRS_PLINK_0.000251188643150958 605 Erectile dysfunction [ED] Male 12 11 11 genitourinary black 11, 12 3, 5 3, 2 2, 2 3, 3 0.479 0.736 0.515 0.288 1.62 0.395 8.59 -0.516 2.21 0.816 0.089 0.597 0.0199 26.5 -5.77 6.65 0.385 0.414 0.00311 2.03e-12 58.3 -0.752 1.78 0.673 0.172 0.471 0.0213 7.98 PRS_PLINK_0.000251188643150958 608 Other disorders of male genital organs Male 3 14 11 genitourinary black 14, 3 4, 0 3, 3 3, 0 4, 0 0.152 0.621 0.807 0.093 1.16 0.36 7 1.68 3.25 0.604 0.219 5.38 0.0731 3540 PRS_PLINK_0.000251188643150958 609 Male infertility and abnormal spermatozoa Male 2 5 11 genitourinary black 5, 2 2, 2 1, 0 1, 0 1, 0 0.0224 3170 1 0 1.02 0.657 1.11 0.177 3530 1 0 1.19 0.492 8.21 -0.098 1410 1 0 0.907 0.574 1.28 0.0444 6470 1 0 1.05 0.452 6.57 PRS_PLINK_0.000251188643150958 609.1 Infertility, male Male 2 5 11 genitourinary black 5, 2 2, 2 1, 0 1, 0 1, 0 0.609 5770 1 0 1.84 0.479 2.84 0.177 3530 1 0 1.19 0.492 8.21 0.0444 6470 1 0 1.05 0.452 6.57 0.0644 10400 1 0 1.07 0.31 12.4 PRS_PLINK_0.000251188643150958 609.11 Azoospermia and oligospermia Male 1 1 11 genitourinary black 1, 1 0.0141 248 1 0 1.01 0.228 2.81 PRS_PLINK_0.000251188643150958 609.2 Abnormal spermatozoa Male 0 2 11 genitourinary black 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 610 Benign mammary dysplasias Female 4 14 11 genitourinary black 14, 4 3, 0 3, 2 3, 0 4, 2 0.0629 0.789 0.936 0.029 1.06 0.213 4.67 2.41 113 0.983 0.007 11.2 5.44 72.4 1.54 2.82 0.585 0.233 4.67 0.115 684 PRS_PLINK_0.000251188643150958 610.1 Cystic mastopathy Female 3 8 11 genitourinary black 8, 3 2, 1 2, 0 2, 0 2, 2 0.479 1.7 0.778 0.109 1.61 0.0593 1520 -0.0977 252 1 0 0.907 0.423 1.27 0.0899 539 1 0 1.09 0.566 3.21 1.35 150 0.993 0.003 3.85 22 613 PRS_PLINK_0.000251188643150958 610.2 Fibroadenosis of breast Female 0 1 11 genitourinary black 1, 0 PRS_PLINK_0.000251188643150958 610.4 Benign neoplasm of breast Female 2 14 11 genitourinary black 14, 2 3, 0 3, 2 3, 0 4, 0 -0.491 0.909 0.589 0.23 0.612 0.126 3.69 2.41 113 0.983 0.007 11.2 5.44 72.4 PRS_PLINK_0.000251188643150958 610.8 Other specified benign mammary dysplasias Female 2 7 11 genitourinary black 7, 2 2, 1 2, 0 1, 0 2, 1 1.01 2.05 0.621 0.207 2.75 0.192 117 2.66 26400000 1 0 14.3 9.36e-19 4.41e+21 -9.48 18200 1 0 7.63e-05 4.46e-18 3.92e+10 -0.0148 280 1 0 0.985 0.48 1.41 PRS_PLINK_0.000251188643150958 611 Abnormal findings on mammogram or breast exam Both 10 17 11 genitourinary black 17, 10 4, 0 4, 3 4, 2 4, 5 0.727 1.29 0.572 0.242 2.07 0.043 345 8.08 41.9 0.847 0.072 3240 1940 5390 -0.572 3.65 0.876 0.058 0.565 0.00197 194 1.25 2.82 0.658 0.182 3.48 0.000174 20000 PRS_PLINK_0.000251188643150958 611.1 Abnormal mammogram Both 8 14 11 genitourinary black 14, 8 3, 0 3, 1 3, 2 4, 5 0.858 1.38 0.535 0.272 2.36 0.0358 128 0.243 758 1 0 1.28 0.487 3.67 -1.48 619 0.998 0.001 0.228 0.211 1.17 -1.68 3.65 0.645 0.19 0.186 3.89e-06 573 PRS_PLINK_0.000251188643150958 611.11 Mammographic microcalcification Both 2 6 11 genitourinary black 6, 2 2, 0 1, 0 1, 0 2, 2 -1.38 599 0.998 0.001 0.252 0.0473 0.189 -0.86 5710 1 0 0.423 0.0803 2.34 PRS_PLINK_0.000251188643150958 611.3 Lump or mass in breast Both 5 16 11 genitourinary black 16, 5 3, 0 4, 3 4, 0 4, 2 -0.453 1.08 0.675 0.171 0.636 0.00164 45.7 -0.0792 4.37 0.986 0.006 0.924 0.0014 945 1.03 201 0.996 0.002 2.79 1.35 13.7 PRS_PLINK_0.000251188643150958 612 Breast conditions, congenital or relating to hormones Both 2 11 11 genitourinary black 11, 2 3, 0 3, 1 2, 1 3, 0 1.79 2.45 0.464 0.333 6.02 0.173 1840 0.558 995000 1 0 1.75 1.03 2.37 -0.0131 15.3 0.999 0 0.987 0.923 1.07 PRS_PLINK_0.000251188643150958 612.1 Galactorrhea Both 0 1 11 genitourinary black 1, 0 PRS_PLINK_0.000251188643150958 612.2 Hypertrophy of breast (Gynecomastia) Both 2 6 11 genitourinary black 6, 2 2, 1 1, 0 1, 1 2, 0 -0.0604 114 1 0 0.941 0.58 1.6 0.00115 43.7 1 0 1 0.905 1.18 -0.00156 36 1 0 0.998 0.908 1.16 -0.0459 632 1 0 0.955 0.431 2 PRS_PLINK_0.000251188643150958 613 Other nonmalignant breast conditions Both 9 25 11 genitourinary black 25, 9 6, 4 6, 1 6, 1 6, 3 -0.087 0.579 0.881 0.055 0.917 0.312 2.78 -2.14 2.03 0.292 0.535 0.118 0.000178 2.66 -1.75 2.13 0.412 0.385 0.174 0.00129 4.39 -0.878 2.5 0.725 0.14 0.416 0.00522 40.6 PRS_PLINK_0.000251188643150958 613.1 Inflammatory disease of breast Both 1 4 11 genitourinary black 4, 1 1, 0 1, 1 1, 0 1, 0 -0.349 13100 1 0 0.705 0.00875 15.5 -0.432 4910 1 0 0.649 0.148 6.11 PRS_PLINK_0.000251188643150958 613.5 Mastodynia Both 3 14 11 genitourinary black 14, 3 4, 3 3, 0 3, 0 4, 0 -0.567 1.13 0.616 0.21 0.567 0.0545 3.53 -0.599 2.76 0.828 0.082 0.549 0.00283 23 0.0714 5.04 0.989 0.005 1.07 0.000406 4750 -0.852 3.58 0.812 0.091 0.427 0.00135 75.5 PRS_PLINK_0.000251188643150958 613.7 Other signs and symptoms in breast Both 4 7 11 genitourinary black 7, 4 2, 1 2, 1 1, 0 2, 2 0.303 1.1 0.784 0.106 1.35 1.18 1.41 -2.24 4.3e+07 1 0 0.106 6.64e-15 54700 -0.979 3530 1 0 0.376 0.00958 43.6 -0.387 1340 1 0 0.679 0.0259 5.76 PRS_PLINK_0.000251188643150958 613.8 Other specified disorders of breast Both 0 7 11 genitourinary black 7, 0 2 2 1 2 PRS_PLINK_0.000251188643150958 613.9 Breast disorder NOS Both 2 10 11 genitourinary black 10, 2 3, 0 2, 1 2, 0 3, 1 -1.52 2.56 0.553 0.257 0.219 1.06e-06 6.08 2.48 419 0.995 0.002 11.9 0.000717 38500 -0.488 489 0.999 0 0.614 4.11e-06 58600 PRS_PLINK_0.000251188643150958 614 Inflammatory diseases of female pelvic organs Female 7 23 11 genitourinary black 23, 7 5, 2 6, 2 5, 2 6, 1 0.139 0.588 0.814 0.09 1.15 0.404 3.63 -0.427 1.71 0.802 0.096 0.652 0.0156 601 0.154 1.78 0.931 0.031 1.17 0.0538 19.9 0.295 1.87 0.875 0.058 1.34 0.000466 37.3 PRS_PLINK_0.000251188643150958 614.1 Pelvic peritoneal adhesions, female (postoperative) (postinfection) Female 1 4 11 genitourinary black 4, 1 1, 0 1, 1 1, 0 1, 0 -0.0323 901000 1 0 0.968 0.162 9.9 PRS_PLINK_0.000251188643150958 614.3 Pelvic inflammatory disease (PID) Female 2 4 11 genitourinary black 4, 2 1, 1 1, 1 1, 0 1, 0 -0.0199 1180 1 0 0.98 0.639 1.45 0.183 9320 1 0 1.2 0.478 1.56 -5.71 155000 1 0 0.00331 3.94e-19 5.43e+21 14.1 1.44e+09 1 0 1340000 7.45e-21 6.81e+26 PRS_PLINK_0.000251188643150958 614.31 Acute inflammatory pelvic disease Female 0 1 11 genitourinary black 1, 0 PRS_PLINK_0.000251188643150958 614.32 Chronic inflammatory pelvic disease Female 1 2 11 genitourinary black 2, 1 1, 1 1, 0 1, 1 1, 0 -0.62 7580 1 0 0.538 0.000861 259 0.483 21700 1 0 1.62 0.0766 1420 PRS_PLINK_0.000251188643150958 614.33 Pelvic inflammatory disease, NOS Female 1 4 11 genitourinary black 4, 1 1, 0 1, 1 1, 0 1, 0 7.81 9.5e+08 1 0 2470 1.57e-09 3.48e+24 0.14 6390 1 0 1.15 0.65 2.21 PRS_PLINK_0.000251188643150958 614.4 Inflammatory diseases of uterus, except cervix Female 0 3 11 genitourinary black 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 614.5 Inflammatory disease of cervix, vagina, and vulva Female 5 23 11 genitourinary black 23, 5 5, 2 6, 1 5, 1 6, 1 -0.0617 0.646 0.924 0.034 0.94 0.268 3.18 -1.59 2.38 0.503 0.298 0.204 0.00933 9 -1.04 2.22 0.64 0.194 0.355 0.000835 8.65 0.295 1.87 0.875 0.058 1.34 0.000466 37.3 PRS_PLINK_0.000251188643150958 614.51 Cervicitis and endocervicitis Female 0 4 11 genitourinary black 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 614.52 Vaginitis and vulvovaginitis Female 2 23 11 genitourinary black 23, 2 5, 0 6, 0 5, 1 6, 1 -0.00428 0.919 0.996 0.002 0.996 0.0014 17.7 -0.274 2.34 0.907 0.043 0.76 0.0109 21.5 0.453 2.26 0.841 0.075 1.57 0.0528 1500 PRS_PLINK_0.000251188643150958 614.53 Cyst or abscess of Bartholin's gland Female 2 2 11 genitourinary black 2, 2 1, 2 1, 0 1, 2 1, 0 -0.492 802 1 0 0.612 0.0495 7.21 -0.191 4.9e+07 1 0 0.826 0.0251 646 PRS_PLINK_0.000251188643150958 614.54 Abscess or ulceration of vulva Female 1 1 11 genitourinary black 1, 1 -0.00134 639 1 0 0.999 0.951 1.03 PRS_PLINK_0.000251188643150958 615 Endometriosis Female 2 18 11 genitourinary black 18, 2 4, 0 4, 2 4, 0 5, 0 -0.206 0.909 0.821 0.086 0.814 0.00691 3340 0.757 3.53 0.83 0.081 2.13 0.0252 372 PRS_PLINK_0.000251188643150958 618 Genital prolapse Female 3 19 11 genitourinary black 19, 3 5, 2 5, 1 4, 0 5, 0 -0.36 1.05 0.733 0.135 0.698 0.0771 7.69 -0.259 2.21 0.907 0.043 0.772 0.0122 32.3 1.43 4.03 0.723 0.141 4.18 0.0107 2450 3.4 10.6 0.749 0.125 29.9 24 37.2 PRS_PLINK_0.000251188643150958 618.1 Prolapse of vaginal walls Female 1 11 11 genitourinary black 11, 1 3, 1 3, 0 2, 0 3, 0 -0.535 3.98 0.893 0.049 0.586 7.31e-05 8400 -0.146 18500000 1 0 0.864 0.225 4.38 0.147 795 1 0 1.16 0.372 4.19 2.14 135 0.987 0.006 8.49 1.06e-06 77100000 PRS_PLINK_0.000251188643150958 618.2 Uterine/Uterovaginal prolapse Female 0 6 11 genitourinary black 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 618.5 Prolapse of vaginal vault after hysterectomy Female 0 3 11 genitourinary black 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 618.6 Vaginal enterocele, congenital or acquired Female 2 7 11 genitourinary black 7, 2 2, 2 2, 0 1, 0 2, 0 -3.97 4.77 0.405 0.392 0.0189 4.01e-06 8.39 0.00409 79.9 1 0 1 0.792 1.33 0.00275 350 1 0 1 0.791 1.38 -0.182 765 1 0 0.833 0.105 13 PRS_PLINK_0.000251188643150958 619 Noninflammatory female genital disorders Female 12 19 11 genitourinary black 19, 12 4, 5 5, 2 4, 1 5, 4 0.129 0.519 0.804 0.095 1.14 0.462 2.95 -0.862 1.55 0.578 0.238 0.422 0.0192 4.71 -2.22 3.23 0.493 0.307 0.109 4.61e-06 11 -0.166 1.41 0.906 0.043 0.847 0.0777 40.9 PRS_PLINK_0.000251188643150958 619.1 Noninflammatory disorders of ovary, fallopian tube, and broad ligament Female 2 12 11 genitourinary black 12, 2 2, 1 3, 1 3, 0 3, 0 0.272 0.887 0.759 0.12 1.31 0.279 13 -0.96 58.3 0.987 0.006 0.383 0.223 0.267 -3.76 2540 0.999 0.001 0.0233 3.83e-09 78400 -0.23 226 0.999 0 0.794 0.0824 2.46 PRS_PLINK_0.000251188643150958 619.2 Disorders of uterus, NEC Female 1 6 11 genitourinary black 6, 1 2, 1 1, 0 1, 0 2, 0 -0.144 1360 1 0 0.866 0.06 17.6 10.8 5930 0.999 0.001 51300 5.17e-10 5.52e+21 2.81 606 0.996 0.002 16.6 8.64e-05 5010000 4.25 1550 0.998 0.001 70.2 6.16e-06 1.48e+08 PRS_PLINK_0.000251188643150958 619.3 Noninflammatory disorders of cervix Female 0 5 11 genitourinary black 5, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 619.4 Noninflammatory disorders of vagina Female 9 18 11 genitourinary black 18, 9 4, 3 4, 2 4, 0 5, 4 0.895 0.725 0.217 0.663 2.45 0.756 13.2 -1.38 2.06 0.503 0.298 0.252 0.000903 4.97 0.561 5.81 0.923 0.035 1.75 1.58 2.06 1.39 2.22 0.533 0.273 4 0.114 269 PRS_PLINK_0.000251188643150958 619.5 Noninflammatory disorders of vulva and perineum Female 2 12 11 genitourinary black 12, 2 3, 2 3, 0 3, 0 3, 0 -0.169 3.6 0.962 0.017 0.844 0.000544 7800 0.772 41.8 0.985 0.006 2.16 0.000598 8010 -0.807 97.4 0.993 0.003 0.446 0.236 0.37 -2.37 1510 0.999 0.001 0.0931 0.0153 0.391 PRS_PLINK_0.000251188643150958 620 Dysplasia of female genital organs Female 0 6 11 genitourinary black 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 620.1 Dysplasia of cervix Female 0 3 11 genitourinary black 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 621 Endometrial hyperplasia Female 0 6 11 genitourinary black 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 622 Polyp of female genital organs Female 3 20 11 genitourinary black 20, 3 5, 1 5, 2 5, 0 5, 0 -0.335 0.89 0.707 0.151 0.715 0.114 3.96 1.61 2.44 0.509 0.293 5.01 0.133 964 -0.121 3.81 0.975 0.011 0.886 0.000163 249 -0.799 5.08 0.875 0.058 0.45 9.07e-07 663 PRS_PLINK_0.000251188643150958 622.1 Polyp of corpus uteri Female 2 14 11 genitourinary black 14, 2 4, 0 3, 2 3, 0 4, 0 0.108 0.992 0.913 0.039 1.11 0.211 8.56 3.74 22.4 0.868 0.062 42 0.633 3090 PRS_PLINK_0.000251188643150958 622.2 Mucous polyp of cervix Female 1 7 11 genitourinary black 7, 1 2, 1 2, 0 1, 0 2, 0 -0.472 147 0.997 0.001 0.624 0.136 2.36 -10.2 4.88e+08 1 0 3.81e-05 3.36e-11 8200 -2.35 1930 0.999 0 0.0952 5.65e-06 105000 -5.03 2310 0.998 0.001 0.00654 6e-09 1590 PRS_PLINK_0.000251188643150958 623 Hypertrophy of female genital organs Female 0 13 11 genitourinary black 13, 0 4 3 3 3 PRS_PLINK_0.000251188643150958 624 Symptoms involving female genital tract Female 4 17 11 genitourinary black 17, 4 4, 1 4, 2 4, 1 4, 0 -0.261 0.746 0.727 0.139 0.771 0.166 3.56 0.568 5.58 0.919 0.037 1.76 1.72 1.83 8.49e-16 3.18 1 0 1 0.0076 143 -0.219 65.7 0.997 0.001 0.803 2.21e-07 240 PRS_PLINK_0.000251188643150958 624.1 Dystrophy of female genital tract Female 1 1 11 genitourinary black 1, 1 5.06 1550 0.997 0.001 158 0.00366 6.2e+14 PRS_PLINK_0.000251188643150958 624.2 Atrophy of female genital tract Female 0 1 11 genitourinary black 1, 0 PRS_PLINK_0.000251188643150958 624.9 stress incontinence, female Female 5 16 11 genitourinary black 16, 5 3, 1 4, 3 4, 0 4, 1 -0.0924 0.891 0.917 0.037 0.912 0.188 8.52 1.89 2.6 0.468 0.33 6.62 0.203 1620 0.0808 5080000 1 0 1.08 0.0297 19.1 5.2 375 0.989 0.005 182 128 257 PRS_PLINK_0.000251188643150958 625 Pain and other symptoms associated with female genital organs Female 11 20 11 genitourinary black 20, 11 4, 3 5, 3 5, 2 5, 3 -0.616 0.714 0.388 0.411 0.54 0.101 2.23 -0.197 1.58 0.901 0.045 0.821 0.058 1520 -0.614 2.18 0.778 0.109 0.541 0.000246 82.1 -0.101 1.89 0.958 0.019 0.904 0.0246 24.9 PRS_PLINK_0.000251188643150958 625.1 Dyspareunia Female 4 14 11 genitourinary black 14, 4 3, 1 3, 1 3, 2 4, 0 -0.493 0.89 0.58 0.237 0.611 0.0974 6.65 1.84 29.5 0.95 0.022 6.31 6 6.66 2.12 132 0.987 0.006 8.36 7.5 8.58 6.14 39.3 0.876 0.058 465 2400 6960 PRS_PLINK_0.000251188643150958 626 Disorders of menstruation and other abnormal bleeding from female genital tract Female 15 15 11 genitourinary black 15, 15 3, 5 4, 4 3, 2 4, 4 0.283 0.566 0.617 0.209 1.33 0.474 4.12 0.657 1.69 0.698 0.156 1.93 0.0506 77.2 -2.05 2.6 0.431 0.366 0.129 0.000835 4.4 -0.144 2.28 0.95 0.022 0.866 0.0219 42.4 PRS_PLINK_0.000251188643150958 626.1 Irregular menstrual cycle/bleeding Female 13 15 11 genitourinary black 15, 13 3, 4 4, 4 3, 2 4, 3 0.19 0.64 0.767 0.115 1.21 0.393 4.2 0.631 1.69 0.708 0.15 1.88 0.0488 81 -2.12 2.7 0.433 0.364 0.121 0.00078 4.05 0.87 3.64 0.811 0.091 2.39 0.00364 323000 PRS_PLINK_0.000251188643150958 626.11 Absent or infrequent menstruation Female 7 10 11 genitourinary black 10, 7 2, 2 2, 2 2, 2 3, 1 -0.799 1.12 0.477 0.322 0.45 0.058 2.36 -1.1 425 0.998 0.001 0.334 0.0332 0.71 0.428 1.6e+07 1 0 1.53 0.0413 31.3 0.777 1510 1 0 2.18 24 208 PRS_PLINK_0.000251188643150958 626.12 Excessive or frequent menstruation Female 9 13 11 genitourinary black 13, 9 3, 4 3, 1 3, 2 3, 2 -0.346 0.825 0.675 0.171 0.707 0.157 3.13 0.657 2.25 0.771 0.113 1.93 0.0725 515 -2.94 2.75 0.285 0.545 0.0527 6.17e-06 1.8 1.05 4.21 0.803 0.095 2.85 0.00242 2450000 PRS_PLINK_0.000251188643150958 626.13 Irregular menstrual cycle Female 6 13 11 genitourinary black 13, 6 3, 3 3, 1 3, 2 3, 0 0.0115 0.825 0.989 0.005 1.01 0.25 4.54 1.33 3.02 0.661 0.18 3.76 0.0707 4.49 -2.53 4.74 0.594 0.226 0.0798 0.0679 5.64 2.38 44 0.957 0.019 10.8 0.308 17200 PRS_PLINK_0.000251188643150958 626.14 Irregular menstrual bleeding Female 3 11 11 genitourinary black 11, 3 2, 3 3, 0 2, 0 3, 0 -0.499 1.35 0.711 0.148 0.607 0.0384 4.26 -0.782 14700000 1 0 0.458 0.00932 1380 -1.65 90.5 0.985 0.006 0.193 0.000203 172 0.372 1980 1 0 1.45 0.0172 0.418 PRS_PLINK_0.000251188643150958 626.15 Infertility, female, associated with anovulation Female 2 6 11 genitourinary black 6, 2 1, 0 1, 0 1, 2 2, 0 1.63 337 0.996 0.002 5.11 0.356 1840 0.0276 102 1 0 1.03 0.941 1.11 PRS_PLINK_0.000251188643150958 626.2 Dysmenorrhea Female 5 12 11 genitourinary black 12, 5 2, 2 3, 0 3, 1 3, 2 0.0233 0.842 0.978 0.01 1.02 0.178 4.66 0.0623 149 1 0 1.06 0.833 1.91 -1.79 97.2 0.985 0.006 0.167 0.0853 0.0304 -0.167 118 0.999 0 0.846 0.00155 5470 PRS_PLINK_0.000251188643150958 626.4 Premenstrual tension syndromes Female 1 2 11 genitourinary black 2, 1 1, 1 1, 0 1, 1 1, 0 0.135 7030 1 0 1.14 0.428 3.57 0.115 1740 1 0 1.12 0.627 2.15 PRS_PLINK_0.000251188643150958 626.8 Infertility, female Female 3 8 11 genitourinary black 8, 3 1, 1 2, 2 2, 0 2, 0 -0.104 1.8 0.954 0.021 0.901 0.0343 22.4 -0.153 780 1 0 0.859 0.275 2.66 -15.4 8560 0.999 0.001 2.15e-07 2.21e-22 4.41e+10 0.232 3710 1 0 1.26 0.187 6.5 PRS_PLINK_0.000251188643150958 627 Menopausal and postmenopausal disorders Female 7 14 11 genitourinary black 14, 7 3, 1 3, 2 3, 3 4, 1 0.0559 0.928 0.952 0.021 1.06 0.221 10 0.00368 117 1 0 1 0.768 1.2 1.63 42.2 0.969 0.014 5.1 1.39e-07 1.91e+08 -0.0278 181 1 0 0.973 0.706 1.56 PRS_PLINK_0.000251188643150958 627.1 Postmenopausal bleeding Female 3 8 11 genitourinary black 8, 3 2, 2 2, 1 2, 0 2, 0 -0.915 1.72 0.596 0.225 0.4 0.0201 4.18 -0.353 810 1 0 0.702 0.000352 445 -2.23 1110 0.998 0.001 0.108 3.06e-17 3.26e+11 -0.1 743 1 0 0.905 0.587 1.28 PRS_PLINK_0.000251188643150958 627.2 Symptomatic menopause Female 2 14 11 genitourinary black 14, 2 3, 0 3, 1 3, 1 4, 0 0.36 1.75 0.837 0.077 1.43 0.0454 419 -0.00771 90.8 1 0 0.992 1.03 1.04 0.0643 2280 1 0 1.07 0.49 1.21 PRS_PLINK_0.000251188643150958 627.21 Symptomatic artificial menopause Female 0 3 11 genitourinary black 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 627.22 Need for Hormone replacement therapy (postmenopausal) Female 0 2 11 genitourinary black 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 627.3 Postmenopausal atrophic vaginitis Female 2 8 11 genitourinary black 8, 2 2, 1 2, 0 2, 0 2, 1 0.578 1.88 0.758 0.12 1.78 0.128 41.8 -0.0155 532 1 0 0.985 0.79 1.18 -0.0516 1350 1 0 0.95 0.432 1.93 0.0135 762 1 0 1.01 0.797 1.63 PRS_PLINK_0.000251188643150958 627.4 Premenopausal menorrhagia Female 4 3 11 genitourinary black 3, 4 1, 3 1, 1 1, 0 1, 3 -0.0419 123 1 0 0.959 0.559 1.2 0.159 53.4 0.998 0.001 1.17 0.56 2.8 -0.137 758 1 0 0.872 0.322 1.4 PRS_PLINK_0.000251188643150958 627.5 Premature menopause and other ovarian failure Female 1 3 11 genitourinary black 3, 1 1, 0 1, 0 0, 1 1, 0 -0.142 2640 1 0 0.868 0.78 2.26 -0.00772 118 1 0 0.992 0.774 1.28 PRS_PLINK_0.000251188643150958 628 Ovarian cyst Female 3 14 11 genitourinary black 14, 3 3, 0 3, 2 3, 0 4, 1 0.216 1.18 0.855 0.068 1.24 0.156 59.2 -0.313 43.1 0.994 0.003 0.731 0.000194 2750 -0.0181 571 1 0 0.982 0.598 1.49 PRS_PLINK_0.000251188643150958 634 Miscarriage; stillbirth Female 4 12 12 pregnancy complications royalblue4 12, 4 2, 0 3, 2 3, 1 3, 1 1.65 1.24 0.183 0.737 5.23 0.86 1330 0.259 962 1 0 1.3 0.825 8.59 -0.193 1270 1 0 0.824 0.686 1.98 0.331 1250 1 0 1.39 0.202 76.3 PRS_PLINK_0.000251188643150958 634.1 Missed abortion/Hydatidiform mole Female 0 5 12 pregnancy complications royalblue4 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 635 Hemorrhage during pregnancy; childbirth and postpartum Female 2 8 12 pregnancy complications royalblue4 8, 2 1, 1 2, 1 2, 0 2, 0 0.0929 1.09 0.932 0.031 1.1 0.19 1.18 0.0281 2050 1 0 1.03 0.535 1.21 -4.3 6.52e+08 1 0 0.0135 3.03e-12 21800000 0.00715 432 1 0 1.01 0.89 1.14 PRS_PLINK_0.000251188643150958 635.2 Antepartum hemorrhage, abruptio placentae, and placenta previa Female 1 6 12 pregnancy complications royalblue4 6, 1 1, 0 1, 0 1, 1 2, 0 -0.443 651 0.999 0 0.642 0.109 1.99 0.375 3720 1 0 1.45 0.606 5.71 PRS_PLINK_0.000251188643150958 635.3 Placenta previa and abruptio placenta Female 2 3 12 pregnancy complications royalblue4 3, 2 0, 1 1, 1 1, 0 0, 1 -0.0442 415 1 0 0.957 0.395 3.1 0.155 12400 1 0 1.17 0.142 65.5 0.00155 2050 1 0 1 0.98 1.02 PRS_PLINK_0.000251188643150958 636 Early or threatened labor; hemorrhage in early pregnancy Female 4 11 12 pregnancy complications royalblue4 11, 4 2, 1 3, 1 2, 0 3, 2 0.388 0.804 0.629 0.201 1.47 0.442 7.79 0.154 724 1 0 1.17 0.213 16.9 4.93 58500000 1 0 138 2.78e-15 1.85e+15 -0.0198 116 1 0 0.98 0.33 1.27 PRS_PLINK_0.000251188643150958 636.1 Threatened premature labor Female 0 7 12 pregnancy complications royalblue4 7, 0 2 2 1 2 PRS_PLINK_0.000251188643150958 636.2 Early onset of delivery Female 1 8 12 pregnancy complications royalblue4 8, 1 1, 1 2, 0 2, 0 2, 0 -1.41 316 0.996 0.002 0.244 2.92e-14 8.82e+11 0.0534 1490 1 0 1.05 0.0265 5.96 -4.3 6.52e+08 1 0 0.0135 3.03e-12 21800000 -28.7 5.32e+08 1 0 3.45e-13 7.17e-31 5.82e+15 PRS_PLINK_0.000251188643150958 636.3 Hemorrhage in early pregnancy Female 3 5 12 pregnancy complications royalblue4 5, 3 2, 1 1, 0 1, 0 1, 2 0.766 982 0.999 0 2.15 2.5 3.26 -2.52 4240000 1 0 0.0801 0.000144 177 0.0789 2480 1 0 1.08 0.785 1.72 0.256 1670000 1 0 1.29 0.236 3.69 PRS_PLINK_0.000251188643150958 636.8 Cervical incompetence Female 0 2 12 pregnancy complications royalblue4 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 637 Short gestation; low birth weight; and fetal growth retardation Both 0 1 12 pregnancy complications royalblue4 1, 0 PRS_PLINK_0.000251188643150958 642 Hypertension complicating pregnancy, childbirth, and the puerperium Female 2 11 12 pregnancy complications royalblue4 11, 2 2, 1 3, 0 2, 0 3, 1 0.0656 1.13 0.954 0.021 1.07 0.0623 7.77 -0.197 973 1 0 0.821 0.274 1.44 2.97 8430 1 0 19.5 0.000808 49000 0.353 4220 1 0 1.42 0.0559 21.3 PRS_PLINK_0.000251188643150958 642.1 Preeclampsia and eclampsia Female 2 5 12 pregnancy complications royalblue4 5, 2 1, 1 1, 0 1, 0 1, 1 -0.777 8690000 1 0 0.46 0.00146 201 0.834 4050 1 0 2.3 0.225 18.5 -5.86 1.12e+09 1 0 0.00284 1.91e-10 572 7.05 9.14e+08 1 0 1150 9.42e-15 8.61e+19 PRS_PLINK_0.000251188643150958 643 Excessive vomiting in pregnancy Female 1 7 12 pregnancy complications royalblue4 7, 1 2, 0 2, 1 1, 0 2, 0 0.0299 641 1 0 1.03 0.564 2.05 0.01 451 1 0 1.01 0.718 1.54 PRS_PLINK_0.000251188643150958 643.1 Hyperemesis gravidarum Female 0 3 12 pregnancy complications royalblue4 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 644 Anemia during pregnancy Female 1 3 12 pregnancy complications royalblue4 3, 1 1, 0 1, 0 0, 1 1, 0 4.21 54900 1 0 67.5 2.42e-07 2.82e+09 -0.014 174 1 0 0.986 0.808 1.2 PRS_PLINK_0.000251188643150958 646 Other complications of pregnancy NEC Female 2 11 12 pregnancy complications royalblue4 11, 2 2, 1 3, 1 2, 0 3, 0 -0.133 0.981 0.892 0.05 0.875 0.103 85.7 0.838 10700000 1 0 2.31 0.156 29.4 -12.1 11300 0.999 0 5.82e-06 1.45e-21 5.21e+11 -0.0991 621 1 0 0.906 0.431 1.89 PRS_PLINK_0.000251188643150958 647 Infectious and parasitic complications affecting pregnancy Female 0 3 12 pregnancy complications royalblue4 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 647.1 Infections of genitourinary tract during pregnancy Female 1 5 12 pregnancy complications royalblue4 5, 1 2, 1 1, 0 1, 0 1, 0 -0.0637 285 1 0 0.938 0.513 1.87 0.0118 2440 1 0 1.01 0.682 1.04 -0.127 14600 1 0 0.881 0.102 12.1 0.145 17700 1 0 1.16 0.28 13.4 PRS_PLINK_0.000251188643150958 647.3 Major puerperal infection Female 0 1 12 pregnancy complications royalblue4 1, 0 PRS_PLINK_0.000251188643150958 649 Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium Female 3 12 12 pregnancy complications royalblue4 12, 3 2, 1 3, 1 3, 0 3, 1 -0.0104 0.982 0.992 0.004 0.99 0.187 8.21 0.0934 14100000 1 0 1.1 0.0615 26.7 1.35 2380 1 0 3.85 0.0154 110 -0.025 267 1 0 0.975 0.274 3.66 PRS_PLINK_0.000251188643150958 649.1 Diabetes or abnormal glucose tolerance complicating pregnancy Female 3 13 12 pregnancy complications royalblue4 13, 3 4, 1 3, 1 3, 0 3, 1 -0.0284 0.95 0.976 0.01 0.972 0.0474 6.25 -1.46 95.4 0.988 0.005 0.233 3.28e-06 0.259 0.216 42.3 0.996 0.002 1.24 0.0181 4.73 1.99 89.1 0.982 0.008 7.33 2.43e-05 2450000 PRS_PLINK_0.000251188643150958 653 Problems associated with amniotic cavity and membranes Female 1 9 12 pregnancy complications royalblue4 9, 1 2, 0 2, 1 2, 0 2, 0 1.01 5.24 0.847 0.072 2.75 2.52 2.96 0.152 2130 1 0 1.16 0.741 2.4 PRS_PLINK_0.000251188643150958 654.1 Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium Female 0 4 12 pregnancy complications royalblue4 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 654.2 Rhesus isoimmunization in pregnancy Female 0 3 12 pregnancy complications royalblue4 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 655 Known or suspected fetal abnormality affecting management of mother Female 3 15 12 pregnancy complications royalblue4 15, 3 3, 1 4, 1 3, 0 4, 1 0.0593 0.694 0.932 0.031 1.06 0.34 3.89 2.67 46.7 0.954 0.02 14.4 0.56 356 0.128 3670 1 0 1.14 0.273 5.42 -0.817 40.2 0.984 0.007 0.442 0.00188 102 PRS_PLINK_0.000251188643150958 655.1 Abnormality in fetal heart rate or rhythm Female 2 12 12 pregnancy complications royalblue4 12, 2 2, 1 3, 1 3, 0 3, 0 0.0999 1.06 0.925 0.034 1.11 0.21 21.5 0.0934 14100000 1 0 1.1 0.0615 26.7 -0.0387 426 1 0 0.962 0.738 1.21 9.7 6200 0.999 0.001 16400 1.8e-09 5.63e+16 PRS_PLINK_0.000251188643150958 656 Other perinatal conditions of fetus or newborn Both 2 13 12 pregnancy complications royalblue4 13, 2 3, 1 3, 1 3, 0 3, 0 -0.302 0.957 0.753 0.123 0.74 0.118 9.13 3.29 52.9 0.95 0.022 26.8 0.1 7740 -0.15 407 1 0 0.86 0.745 2.71 -0.0256 1220 1 0 0.975 0.563 1.57 PRS_PLINK_0.000251188643150958 656.2 Respiratory conditions of fetus and newborn Both 0 3 12 pregnancy complications royalblue4 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 669 Complications of labor and delivery NEC Female 1 15 12 pregnancy complications royalblue4 15, 1 3, 1 4, 0 3, 0 4, 0 -0.567 0.962 0.555 0.256 0.567 0.0184 3.84 -0.844 53.4 0.987 0.006 0.43 0.00154 118 -0.15 407 1 0 0.86 0.745 2.71 -0.00492 29.4 1 0 0.995 0.63 1.36 PRS_PLINK_0.000251188643150958 671 Venous/cerebrovascular complications embolism in pregnancy and the puerperium Female 0 6 12 pregnancy complications royalblue4 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 674 Other complications of the puerperium NEC Female 0 4 12 pregnancy complications royalblue4 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 676 Other disorders of the breast associated with childbirth and disorders of lactation Female 0 5 12 pregnancy complications royalblue4 5, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 681 Superficial cellulitis and abscess Both 13 50 13 dermatologic firebrick 50, 13 12, 0 12, 5 12, 2 13, 6 0.357 0.36 0.322 0.492 1.43 0.719 2.89 1.95 1.4 0.163 0.787 7.06 0.656 959 2.27 1.85 0.221 0.656 9.64 0.347 75900 1.17 1.44 0.418 0.379 3.23 0.259 703 PRS_PLINK_0.000251188643150958 681.1 Cellulitis and abscess of fingers/toes Both 4 24 13 dermatologic firebrick 24, 4 6, 0 6, 0 6, 2 6, 2 0.171 0.683 0.802 0.096 1.19 0.118 5.18 1.83 3.01 0.544 0.264 6.23 0.0288 2300 0.368 2.26 0.871 0.06 1.44 0.00215 63.3 PRS_PLINK_0.000251188643150958 681.2 Cellulitis and abscess of face/neck Both 2 21 13 dermatologic firebrick 21, 2 5, 0 5, 1 5, 0 5, 1 -0.145 1.2 0.904 0.044 0.865 0.0168 21.5 -1.3 12.9 0.92 0.036 0.273 1.75e-07 466000 0.176 3.81 0.963 0.016 1.19 0.00398 76.8 PRS_PLINK_0.000251188643150958 681.3 Cellulitis and abscess of arm/hand Both 5 30 13 dermatologic firebrick 30, 5 8, 0 7, 3 7, 0 8, 2 0.408 0.513 0.427 0.369 1.5 0.598 8.56 2.4 2.13 0.26 0.584 11 0.428 8140 1.65 1.73 0.34 0.468 5.2 0.328 238 PRS_PLINK_0.000251188643150958 681.5 Cellulitis and abscess of leg, except foot Both 5 31 13 dermatologic firebrick 31, 5 8, 0 8, 3 7, 0 8, 2 0.0469 0.544 0.931 0.031 1.05 0.267 4.78 1.39 1.43 0.334 0.476 4 0.371 162000 0.718 1.95 0.713 0.147 2.05 0.000831 500 PRS_PLINK_0.000251188643150958 681.6 Cellulitis and abscess of foot, toe Both 5 26 13 dermatologic firebrick 26, 5 7, 0 6, 2 6, 1 7, 2 0.23 0.676 0.733 0.135 1.26 0.257 12.7 0.175 1.68 0.917 0.038 1.19 0.012 82 1.45 2.18 0.506 0.296 4.27 0.213 4.83 0.243 1.72 0.888 0.052 1.27 0.0415 114 PRS_PLINK_0.000251188643150958 681.7 Cellulitis and abscess of trunk Both 2 27 13 dermatologic firebrick 27, 2 7, 0 7, 1 6, 0 7, 1 -0.13 0.665 0.845 0.073 0.878 0.0541 15.1 0.0209 1.93 0.991 0.004 1.02 0.0094 273 1.09 2.5 0.663 0.178 2.96 0.00253 333 PRS_PLINK_0.000251188643150958 686 Other local infections of skin and subcutaneous tissue Both 2 26 13 dermatologic firebrick 26, 2 7, 0 6, 1 6, 0 7, 1 0.134 0.609 0.826 0.083 1.14 0.368 4.98 1.78 2.4 0.458 0.339 5.95 0.182 6.9 0.572 2.23 0.797 0.098 1.77 0.00154 75.8 PRS_PLINK_0.000251188643150958 686.1 Carbuncle and furuncle Both 1 14 13 dermatologic firebrick 14, 1 4, 1 3, 0 3, 0 4, 0 -0.244 0.904 0.787 0.104 0.783 0.0343 4.25 0.0527 229 1 0 1.05 0.593 2.1 -0.0461 176 1 0 0.955 0.808 1.11 -2.33 79.2 0.977 0.01 0.0975 0.000858 10.2 PRS_PLINK_0.000251188643150958 686.2 Impetigo Both 0 5 13 dermatologic firebrick 5, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 686.3 Pilonidal cyst Both 1 6 13 dermatologic firebrick 6, 1 2, 1 1, 0 1, 0 2, 0 0.627 7800000 1 0 1.87 0.233 2090 0.00303 34.9 1 0 1 0.953 1.05 0.00184 38.7 1 0 1 0.904 1.02 0.00857 36.6 1 0 1.01 0.933 1.09 PRS_PLINK_0.000251188643150958 686.4 Pyogenic granuloma Both 0 3 13 dermatologic firebrick 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 686.5 Pyoderma Both 1 2 13 dermatologic firebrick 2, 1 1, 1 1, 0 1, 1 1, 0 0.0139 55.8 1 0 1.01 0.935 1.16 0.00929 64.4 1 0 1.01 0.888 1.09 PRS_PLINK_0.000251188643150958 687 Symptoms affecting skin Both 4 18 13 dermatologic firebrick 18, 4 4, 1 4, 1 4, 1 5, 1 -0.131 0.572 0.819 0.087 0.878 0.0381 7.42 -0.31 7.17 0.965 0.015 0.733 0.71 0.761 -4.5 21.1 0.831 0.081 0.0111 7.31e-05 0.012 -0.396 3.19 0.901 0.045 0.673 0.00301 75.5 PRS_PLINK_0.000251188643150958 687.1 Rash and other nonspecific skin eruption Both 22 36 13 dermatologic firebrick 36, 22 8, 4 9, 7 9, 7 9, 4 0.0418 0.31 0.893 0.049 1.04 0.578 1.85 0.276 1.14 0.808 0.092 1.32 0.177 10.8 0.126 1.25 0.92 0.036 1.13 0.107 10.9 0.599 1.36 0.658 0.182 1.82 0.185 135 PRS_PLINK_0.000251188643150958 687.3 Changes in skin texture Both 2 8 13 dermatologic firebrick 8, 2 2, 0 2, 1 2, 0 2, 1 -0.0606 15.1 0.997 0.001 0.941 0.945 9.04 1.5 16800 1 0 4.48 2.11e-06 1620000 28.3 9230 0.998 0.001 1.92e+12 1.32e-30 1.11e+62 PRS_PLINK_0.000251188643150958 687.4 Disturbance of skin sensation Both 9 36 13 dermatologic firebrick 36, 9 8, 3 9, 4 9, 2 9, 0 -0.305 0.509 0.549 0.261 0.737 0.255 2.01 -1.34 1.5 0.373 0.428 0.263 0.00934 3.17 -1.54 1.53 0.315 0.502 0.215 0.00689 2.53 -1.44 2.26 0.523 0.281 0.237 1.7e-10 13.2 PRS_PLINK_0.000251188643150958 689 Disorder of skin and subcutaneous tissue NOS Both 16 48 13 dermatologic firebrick 48, 16 11, 2 12, 2 12, 6 12, 6 0.237 0.392 0.546 0.263 1.27 0.582 2.76 -0.706 1.22 0.562 0.25 0.494 0.0281 4.53 0.397 1.08 0.712 0.147 1.49 0.192 12.6 0.616 1.23 0.616 0.21 1.85 0.175 32.5 PRS_PLINK_0.000251188643150958 690 Erythematosquamous dermatosis Both 9 32 13 dermatologic firebrick 32, 9 7, 3 8, 1 8, 4 8, 1 -0.939 0.632 0.137 0.863 0.391 0.0589 1.43 -2.06 1.79 0.25 0.602 0.128 4.93e-05 2.25 -1.82 1.69 0.282 0.55 0.162 0.000275 3.89 0.0845 1.56 0.957 0.019 1.09 0.0198 19.9 PRS_PLINK_0.000251188643150958 690.1 Seborrheic dermatitis Both 9 32 13 dermatologic firebrick 32, 9 7, 3 8, 1 8, 4 8, 1 -0.939 0.632 0.137 0.863 0.391 0.0589 1.43 -2.06 1.79 0.25 0.602 0.128 4.93e-05 2.25 -1.82 1.69 0.282 0.55 0.162 0.000275 3.89 0.0845 1.56 0.957 0.019 1.09 0.0198 19.9 PRS_PLINK_0.000251188643150958 691 Congenital anomalies of skin Both 1 10 13 dermatologic firebrick 10, 1 3, 0 2, 0 2, 0 3, 1 -5.93 83.2 0.943 0.025 0.00266 0.0017 0.00425 -5.61 9370 1 0 0.00368 1.05e-26 5.49e+24 PRS_PLINK_0.000251188643150958 691.3 Congenital pigmentary anomalies of skin Both 0 2 13 dermatologic firebrick 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 694 Dyschromia and Vitiligo Both 4 22 13 dermatologic firebrick 22, 4 6, 1 5, 1 5, 1 6, 1 -1.23 0.915 0.179 0.748 0.292 0.00996 1.38 -1.66 5.59 0.766 0.116 0.189 5.97e-08 1040 0.132 2.15 0.951 0.022 1.14 0.00992 1510 -0.784 2.26 0.729 0.137 0.457 0.00884 47.9 PRS_PLINK_0.000251188643150958 694.1 Vitiligo Both 1 3 13 dermatologic firebrick 3, 1 1, 0 1, 0 1, 1 1, 0 0.0731 4820 1 0 1.08 0.322 1.2 0.0242 82.7 1 0 1.02 0.914 1.25 PRS_PLINK_0.000251188643150958 694.2 Other dyschromia Both 3 19 13 dermatologic firebrick 19, 3 5, 1 5, 1 4, 1 5, 0 -1.07 0.949 0.258 0.588 0.342 0.000384 1.64 1.44 7.2 0.841 0.075 4.22 0.000155 827000 0.52 2.25 0.817 0.088 1.68 0.0511 64.7 -0.0925 2.17 0.966 0.015 0.912 0.0301 27.3 PRS_PLINK_0.000251188643150958 694.3 Vascular disorders of skin Both 0 1 13 dermatologic firebrick 1, 0 PRS_PLINK_0.000251188643150958 695 Erythematous conditions Both 13 33 13 dermatologic firebrick 33, 13 8, 0 8, 5 8, 7 8, 1 -0.0646 0.402 0.872 0.059 0.937 0.423 1.98 2.5 1.7 0.142 0.848 12.2 0.82 2930 1.66 1.55 0.285 0.545 5.25 0.451 1.23e+08 0.47 1.56 0.762 0.118 1.6 0.00255 33.2 PRS_PLINK_0.000251188643150958 695.2 Bullous dermatoses Both 0 1 13 dermatologic firebrick 1, 0 PRS_PLINK_0.000251188643150958 695.3 Rosacea Both 3 18 13 dermatologic firebrick 18, 3 4, 0 4, 0 4, 2 5, 1 0.539 0.837 0.519 0.284 1.71 0.366 15.5 -1.62 116 0.989 0.005 0.197 8.1e-06 4430 2.64 191 0.989 0.005 14 0.000202 495000 PRS_PLINK_0.000251188643150958 695.4 Lupus (localized and systemic) Both 3 10 13 dermatologic firebrick 10, 3 3, 2 2, 1 2, 0 3, 0 -0.912 1.39 0.513 0.29 0.402 0.0138 3.62 0.00813 109 1 0 1.01 0.344 5.23 -0.975 25200000 1 0 0.377 1.28e-05 20600 -1.31 30.4 0.966 0.015 0.27 0.00883 61600 PRS_PLINK_0.000251188643150958 695.41 Cutaneous lupus erythematosus Both 1 3 13 dermatologic firebrick 3, 1 1, 0 1, 0 0, 1 1, 0 0.0967 18300 1 0 1.1 0.035 97200 -0.0127 71.8 1 0 0.987 0.848 1.17 PRS_PLINK_0.000251188643150958 695.42 Systemic lupus erythematosus Both 3 9 13 dermatologic firebrick 9, 3 3, 1 2, 2 2, 0 2, 0 -1.04 1.56 0.505 0.297 0.352 0.0253 3.03 -0.439 104 0.997 0.001 0.645 0.00795 36.2 -0.0129 200 1 0 0.987 0.599 1.28 0.0621 4940000 1 0 1.06 0.0625 8.02 PRS_PLINK_0.000251188643150958 695.7 Prurigo and Lichen Both 3 3 13 dermatologic firebrick 3, 3 1, 1 1, 2 1, 0 1, 1 -0.469 5390 1 0 0.625 0.451 2 -0.625 10200 1 0 0.535 0.477 2.79 -0.0187 140 1 0 0.982 0.932 1.11 PRS_PLINK_0.000251188643150958 695.8 Other specified erythematous conditions Both 4 7 13 dermatologic firebrick 7, 4 2, 1 2, 1 1, 2 2, 0 -1.14 2.14 0.593 0.227 0.319 0.00822 5.69 -0.779 13200000 1 0 0.459 0.000401 168 0.0385 26.9 0.999 0 1.04 0.748 1.41 0.0726 444 1 0 1.08 0.852 1.18 PRS_PLINK_0.000251188643150958 695.9 Unspecified erythematous condition Both 0 8 13 dermatologic firebrick 8, 0 2 2 2 2 PRS_PLINK_0.000251188643150958 696 Psoriasis and related disorders Both 4 9 13 dermatologic firebrick 9, 4 3, 0 2, 2 2, 0 2, 2 1.69 2.9 0.561 0.251 5.42 0.0826 427000 0.122 1510 1 0 1.13 0.0661 40.3 1.1 499 0.998 0.001 3.02 0.128 159 PRS_PLINK_0.000251188643150958 696.3 Pityriasis Both 1 3 13 dermatologic firebrick 3, 1 1, 0 1, 0 0, 1 1, 0 7.36 23400 1 0 1570 1.42e-07 2.48e+11 -0.00636 160 1 0 0.994 0.26 2.39 PRS_PLINK_0.000251188643150958 696.4 Psoriasis Both 3 10 13 dermatologic firebrick 10, 3 3, 0 2, 0 2, 1 3, 2 -1.59 3 0.596 0.225 0.204 0.000111 19.7 0.0478 1990 1 0 1.05 0.437 1.15 -0.572 702 0.999 0 0.564 0.55 1.79 PRS_PLINK_0.000251188643150958 696.41 Psoriasis vulgaris Both 3 8 13 dermatologic firebrick 8, 3 2, 0 2, 1 2, 2 2, 0 5.8 16.6 0.727 0.138 329 0.000621 409 -0.123 6750 1 0 0.884 0.0599 9.54 -0.0627 275 1 0 0.939 0.414 3.22 PRS_PLINK_0.000251188643150958 696.42 Psoriatic arthropathy Both 1 2 13 dermatologic firebrick 2, 1 1, 0 1, 1 1, 0 1, 1 0.0109 350 1 0 1.01 0.542 2.16 -0.000377 44.8 1 0 1 0.925 1.09 PRS_PLINK_0.000251188643150958 697 Sarcoidosis Both 0 4 13 dermatologic firebrick 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 698 Pruritus and related conditions Both 3 33 13 dermatologic firebrick 33, 3 9, 0 8, 2 8, 0 8, 1 -0.0308 0.68 0.964 0.016 0.97 0.179 4.18 0.865 1.35 0.521 0.283 2.37 0.137 401 0.167 1.8 0.926 0.033 1.18 0.00245 88 PRS_PLINK_0.000251188643150958 700 Corns and callosities Both 10 20 13 dermatologic firebrick 20, 10 5, 2 5, 2 5, 2 5, 4 1.32 0.93 0.157 0.805 3.73 0.79 28500 1.66 5.2 0.749 0.126 5.27 0.00503 11700 -0.45 3.51 0.898 0.047 0.638 0.00115 43100 0.229 2.23 0.918 0.037 1.26 0.0131 66.2 PRS_PLINK_0.000251188643150958 701 Other hypertrophic and atrophic conditions of skin Both 9 47 13 dermatologic firebrick 47, 9 11, 0 12, 5 11, 3 12, 1 0.302 0.408 0.459 0.338 1.35 0.609 3.22 2.35 1.61 0.145 0.839 10.4 0.736 50800 1.16 1.51 0.445 0.351 3.17 0.196 260 0.572 1.47 0.697 0.157 1.77 0.00901 119 PRS_PLINK_0.000251188643150958 701.1 Keratoderma, acquired Both 2 8 13 dermatologic firebrick 8, 2 2, 0 2, 0 2, 2 2, 0 -0.394 2.08 0.85 0.071 0.674 0.0331 28 0.26 122 0.998 0.001 1.3 0.153 7.26 PRS_PLINK_0.000251188643150958 701.2 Scar conditions and fibrosis of skin Both 1 24 13 dermatologic firebrick 24, 1 6, 0 6, 0 6, 1 6, 0 -0.0481 0.851 0.955 0.02 0.953 0.063 7.71 0.018 3.36 0.996 0.002 1.02 8.52e-05 2740 PRS_PLINK_0.000251188643150958 701.3 Circumscribed scleroderma Both 1 8 13 dermatologic firebrick 8, 1 2, 0 2, 1 2, 0 2, 0 -0.0268 1550 1 0 0.974 0.395 2.14 2.26 7310 1 0 9.55 1.89e-17 5.54e+15 PRS_PLINK_0.000251188643150958 701.4 Keloid scar Both 0 5 13 dermatologic firebrick 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 701.5 Abnormal granulation tissue Both 0 4 13 dermatologic firebrick 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 702 Degenerative skin conditions and other dermatoses Both 11 31 13 dermatologic firebrick 31, 11 8, 3 8, 1 7, 1 8, 6 -1.01 0.857 0.241 0.619 0.366 0.00541 2.02 -1.05 1.47 0.474 0.324 0.349 0.00115 12.6 -0.269 1.87 0.886 0.053 0.764 0.00299 937 -1.02 1.74 0.557 0.254 0.359 0.000715 18.7 PRS_PLINK_0.000251188643150958 702.1 Actinic keratosis Both 3 28 13 dermatologic firebrick 28, 3 7, 0 7, 0 7, 0 7, 3 0.677 1 0.499 0.302 1.97 0.0963 178 1.53 1.88 0.415 0.382 4.63 0.233 604 PRS_PLINK_0.000251188643150958 702.2 Seborrheic keratosis Both 9 32 13 dermatologic firebrick 32, 9 8, 3 8, 1 8, 2 8, 3 -0.478 0.718 0.505 0.296 0.62 0.0593 2.51 0.00864 1.44 0.995 0.002 1.01 0.0729 15.7 -1.35 1.66 0.417 0.379 0.26 0.00027 5.86 0.627 1.5 0.675 0.17 1.87 0.107 30.7 PRS_PLINK_0.000251188643150958 702.4 Degenerative skin disorders Both 0 1 13 dermatologic firebrick 1, 0 PRS_PLINK_0.000251188643150958 703 Diseases of nail, NOS Both 8 20 13 dermatologic firebrick 20, 8 5, 3 5, 1 5, 2 5, 2 -0.126 0.768 0.87 0.06 0.882 0.191 3.99 -0.711 2.32 0.759 0.12 0.491 8.66e-10 18.3 0.412 1.33 0.756 0.121 1.51 0.179 16 -0.59 1.99 0.767 0.115 0.554 7.56e-09 22.2 PRS_PLINK_0.000251188643150958 703.1 Ingrowing nail Both 5 18 13 dermatologic firebrick 18, 5 5, 1 4, 1 4, 2 5, 1 0.154 0.9 0.864 0.064 1.17 0.228 5.7 -0.329 2.63 0.9 0.046 0.72 0.00251 142 0.657 1.56 0.673 0.172 1.93 0.174 32.8 0.0146 1.86 0.994 0.003 1.01 0.0277 45.2 PRS_PLINK_0.000251188643150958 704 Diseases of hair and hair follicles Both 9 40 13 dermatologic firebrick 40, 9 9, 2 10, 5 10, 0 10, 2 -0.17 0.412 0.68 0.168 0.844 0.376 1.84 0.753 1.22 0.536 0.271 2.12 0.204 27.2 -1.5 1.99 0.449 0.347 0.223 0.000234 5.73 0.164 1.23 0.894 0.049 1.18 0.113 11.2 PRS_PLINK_0.000251188643150958 704.1 Alopecia Both 2 17 13 dermatologic firebrick 17, 2 5, 1 4, 0 4, 1 4, 0 -0.246 1.13 0.827 0.082 0.782 0.0812 5.59 -0.107 57.2 0.999 0.001 0.899 0.694 1.2 -3.02 60.2 0.96 0.018 0.0487 0.0369 0.0637 -2.1 14.3 0.883 0.054 0.122 0.0704 0.196 PRS_PLINK_0.000251188643150958 704.11 Alopecia Areata Both 1 2 13 dermatologic firebrick 2, 1 0, 1 1, 0 0, 1 1, 0 -0.0167 102 1 0 0.983 0.938 1.11 0.00386 46.3 1 0 1 0.787 1.12 PRS_PLINK_0.000251188643150958 704.2 Hirsutism Both 3 3 13 dermatologic firebrick 3, 3 1, 0 1, 0 1, 3 1, 0 -1.16 7.5e+07 1 0 0.315 1.88e-07 2800 1.75 1550 0.999 0 5.78 1.39e-06 19100000 PRS_PLINK_0.000251188643150958 704.8 Other specified diseases of hair and hair follicles Both 7 24 13 dermatologic firebrick 24, 7 6, 3 6, 2 6, 0 6, 2 -0.21 0.52 0.687 0.163 0.811 0.311 2.01 1.27 1.87 0.496 0.305 3.58 0.182 5910 0.488 3.25 0.881 0.055 1.63 2e-04 270 -0.00149 1.5 0.999 0 0.999 0.036 11.3 PRS_PLINK_0.000251188643150958 705 Disorders of sweat glands Both 1 7 13 dermatologic firebrick 7, 1 2, 0 2, 0 1, 0 2, 1 -0.283 4180000 1 0 0.754 0.0325 48.8 -14.8 16000 0.999 0 3.68e-07 2.27e-35 2.17e+21 PRS_PLINK_0.000251188643150958 705.1 Dyshidrosis Both 0 1 13 dermatologic firebrick 1, 0 PRS_PLINK_0.000251188643150958 705.3 Hidradenitis Both 0 5 13 dermatologic firebrick 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 705.8 Hyperhidrosis Both 3 15 13 dermatologic firebrick 15, 3 4, 1 4, 2 3, 0 4, 0 -0.553 0.895 0.537 0.27 0.575 0.0115 2.22 0.163 3.18 0.959 0.018 1.18 0.002 2340 0.076 885 1 0 1.08 0.871 1.75 -0.305 3470000 1 0 0.737 0.00914 48.1 PRS_PLINK_0.000251188643150958 706 Diseases of sebaceous glands Both 19 43 13 dermatologic firebrick 43, 19 10, 3 11, 7 10, 5 11, 4 -0.231 0.339 0.496 0.305 0.794 0.406 1.48 1.12 1.05 0.288 0.541 3.06 0.505 45.3 0.133 1.23 0.914 0.039 1.14 0.112 13.5 0.139 1.03 0.893 0.049 1.15 0.183 7.07 PRS_PLINK_0.000251188643150958 706.1 Acne Both 6 32 13 dermatologic firebrick 32, 6 7, 2 8, 2 8, 1 8, 1 -0.299 0.452 0.509 0.294 0.742 0.266 1.62 0.605 1.42 0.67 0.174 1.83 0.0791 33.8 -0.845 1.95 0.665 0.177 0.43 7.51e-05 19.3 -0.845 1.83 0.644 0.191 0.43 0.000215 43.9 PRS_PLINK_0.000251188643150958 706.2 Sebaceous cyst Both 9 29 13 dermatologic firebrick 29, 9 8, 0 7, 6 7, 2 7, 1 -0.149 0.525 0.777 0.109 0.862 0.301 2.16 3.2 2.07 0.121 0.918 24.6 1.18 40800 1.64 1.99 0.412 0.385 5.13 0.087 402 0.213 2.03 0.916 0.038 1.24 0.00922 186 PRS_PLINK_0.000251188643150958 706.3 Seborrhea Both 0 1 13 dermatologic firebrick 1, 0 PRS_PLINK_0.000251188643150958 706.8 Other specified diseases of sebaceous glands Both 9 18 13 dermatologic firebrick 18, 9 5, 1 4, 2 4, 3 5, 3 -1.07 0.897 0.234 0.631 0.344 2.2e-05 1.44 0.0715 3.08 0.981 0.008 1.07 0.919 1.19 -1.23 8.55 0.886 0.053 0.294 0.268 0.328 0.329 1.95 0.866 0.063 1.39 0.0517 29.8 PRS_PLINK_0.000251188643150958 707 Chronic ulcer of skin Both 7 35 13 dermatologic firebrick 35, 7 9, 1 9, 2 8, 0 9, 4 0.0396 0.5 0.937 0.028 1.04 0.41 3 0.246 1.69 0.884 0.053 1.28 0.00128 29.6 -0.522 1.78 0.77 0.114 0.593 0.0135 139 0.726 1.26 0.566 0.247 2.07 0.222 479 PRS_PLINK_0.000251188643150958 707.1 Decubitus ulcer Both 2 14 13 dermatologic firebrick 14, 2 4, 0 3, 1 3, 0 4, 1 0.461 1.37 0.737 0.133 1.59 0.085 65.2 0.12 2180 1 0 1.13 0.692 3.08 -0.907 22.1 0.967 0.014 0.404 0.0124 17.3 PRS_PLINK_0.000251188643150958 707.2 Chronic ulcer of leg or foot Both 4 21 13 dermatologic firebrick 21, 4 6, 1 5, 2 5, 0 5, 1 -0.332 0.741 0.655 0.184 0.718 0.0295 4.05 -0.339 1.87 0.856 0.067 0.712 0.0247 14.3 -0.0516 2.84 0.986 0.006 0.95 0.0111 802 0.636 2.13 0.765 0.116 1.89 0.022 120 PRS_PLINK_0.000251188643150958 707.3 Chronic ulcer of unspecified site Both 2 21 13 dermatologic firebrick 21, 2 6, 0 5, 0 5, 0 5, 2 -0.467 1.12 0.676 0.17 0.627 0.00645 18.9 -1.46 4.71 0.757 0.121 0.232 1.11e-05 291 PRS_PLINK_0.000251188643150958 709 Diffuse diseases of connective tissue Both 5 18 13 dermatologic firebrick 18, 5 5, 1 4, 1 4, 3 5, 0 -0.254 1.13 0.822 0.085 0.776 0.0609 8.21 1.43 15.2 0.925 0.034 4.18 0.00016 142000 3.63 5.2 0.485 0.315 37.8 0.0365 474000 1.44e-13 8.82 1 0 1 6.25e-07 1640000 PRS_PLINK_0.000251188643150958 709.2 Sicca syndrome Both 3 7 13 dermatologic firebrick 7, 3 2, 2 2, 0 1, 1 2, 0 0.473 13.9 0.973 0.012 1.61 3.35 6.63 9.34 2170 0.997 0.001 11400 5.79e-14 6.59e+19 -0.148 323 1 0 0.863 0.123 5.34 0.385 1700 1 0 1.47 1.29e-06 35800 PRS_PLINK_0.000251188643150958 709.7 Unspecified diffuse connective tissue disease Both 3 14 13 dermatologic firebrick 14, 3 4, 0 3, 2 3, 1 4, 0 -0.693 1.45 0.633 0.199 0.5 5.14e-05 9.73 -5.32 149 0.972 0.013 0.00489 3.18e-10 0.0061 -0.428 1180 1 0 0.652 0.633 1.4 PRS_PLINK_0.000251188643150958 710 Osteomyelitis, periostitis, and other infections involving bone Both 2 17 14 musculoskeletal darkolivegreen 17, 2 5, 0 4, 1 4, 0 4, 1 0.0495 0.929 0.958 0.019 1.05 0.00548 12.8 0.985 2.14 0.646 0.19 2.68 0.162 93.8 -1.7 7.3 0.815 0.089 0.182 0.161 0.205 PRS_PLINK_0.000251188643150958 710.1 Osteomyelitis Both 2 18 14 musculoskeletal darkolivegreen 18, 2 5, 0 4, 1 4, 0 5, 1 0.106 0.852 0.901 0.045 1.11 0.00658 11.7 0.93 2.53 0.714 0.146 2.53 0.323 32.4 -1.1 4.96 0.825 0.084 0.333 1.3e-05 290 PRS_PLINK_0.000251188643150958 710.11 Acute osteomyelitis Both 0 8 14 musculoskeletal darkolivegreen 8, 0 2 2 2 2 PRS_PLINK_0.000251188643150958 710.12 Chronic osteomyelitis Both 0 10 14 musculoskeletal darkolivegreen 10, 0 3 2 2 3 PRS_PLINK_0.000251188643150958 710.19 Unspecified osteomyelitis Both 2 18 14 musculoskeletal darkolivegreen 18, 2 5, 0 4, 1 4, 0 5, 1 0.283 0.871 0.746 0.127 1.33 0.00999 8.58 1.03 2.21 0.642 0.193 2.8 0.0919 85.7 0.149 1.94 0.939 0.027 1.16 0.00705 22.4 PRS_PLINK_0.000251188643150958 711 Arthropathy associated with infections Both 0 6 14 musculoskeletal darkolivegreen 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 711.1 Pyogenic arthritis Both 0 2 14 musculoskeletal darkolivegreen 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 712 Infective connective tissue disorders Both 0 1 14 musculoskeletal darkolivegreen 1, 0 PRS_PLINK_0.000251188643150958 713 Arthropathy associated with other disorders classified elsewhere Both 3 9 14 musculoskeletal darkolivegreen 9, 3 3, 0 2, 0 2, 0 2, 3 -0.223 297 0.999 0 0.8 0.345 0.678 -0.029 405 1 0 0.971 0.468 1.3 PRS_PLINK_0.000251188643150958 713.5 Arthropathy associated with neurological disorders Both 3 6 14 musculoskeletal darkolivegreen 6, 3 2, 0 1, 0 1, 0 2, 3 0.12 911 1 0 1.13 0.774 2.3 -0.0238 381 1 0 0.976 0.472 1.36 PRS_PLINK_0.000251188643150958 714 Rheumatoid arthritis and other inflammatory polyarthropathies Both 4 19 14 musculoskeletal darkolivegreen 19, 4 5, 1 5, 2 4, 1 5, 0 -0.344 0.744 0.643 0.192 0.709 0.086 2.42 1.49 2.17 0.491 0.309 4.44 0.285 5.05 -1.24 7.93 0.876 0.058 0.29 0.12 2160 -0.108 5.02 0.983 0.007 0.898 0.804 0.994 PRS_PLINK_0.000251188643150958 714.1 Rheumatoid arthritis Both 1 13 14 musculoskeletal darkolivegreen 13, 1 4, 0 3, 1 3, 0 3, 0 0.236 1.86 0.899 0.046 1.27 0.00229 897 0.139 1860 1 0 1.15 0.764 5.32 PRS_PLINK_0.000251188643150958 714.2 Juvenile rheumatoid arthritis Both 0 2 14 musculoskeletal darkolivegreen 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 715 Other inflammatory spondylopathies Both 4 8 14 musculoskeletal darkolivegreen 8, 4 2, 0 2, 2 2, 1 2, 1 -0.867 2.99 0.772 0.113 0.42 0.00444 29.2 0.0394 2390000 1 0 1.04 0.189 15.4 0.0559 599 1 0 1.06 0.837 1.42 0.143 5860 1 0 1.15 0.117 4.1 PRS_PLINK_0.000251188643150958 715.1 Sacroiliitis NEC Both 2 1 14 musculoskeletal darkolivegreen 1, 2 0.362 774000 1 0 1.44 0.482 4.94 PRS_PLINK_0.000251188643150958 715.2 Ankylosing spondylitis Both 1 3 14 musculoskeletal darkolivegreen 3, 1 1, 0 1, 1 1, 0 1, 0 0.201 1860 1 0 1.22 0.736 4.08 0.613 4430 1 0 1.85 0.518 1.93 PRS_PLINK_0.000251188643150958 716 Other arthropathies Both 18 42 14 musculoskeletal darkolivegreen 42, 18 10, 3 10, 6 10, 4 11, 5 -0.0748 0.373 0.841 0.075 0.928 0.437 1.87 0.103 1.12 0.927 0.033 1.11 0.142 8.38 -1.57 1.49 0.292 0.534 0.207 0.00125 2.58 -0.0187 1.22 0.988 0.005 0.981 0.037 15.2 PRS_PLINK_0.000251188643150958 716.1 Unspecified polyarthropathy or polyarthritis Both 1 0 14 musculoskeletal darkolivegreen 0, 1 PRS_PLINK_0.000251188643150958 716.9 Arthropathy NOS Both 18 42 14 musculoskeletal darkolivegreen 42, 18 10, 3 10, 6 10, 4 11, 5 -0.0748 0.373 0.841 0.075 0.928 0.437 1.87 0.103 1.12 0.927 0.033 1.11 0.142 8.38 -1.57 1.49 0.292 0.534 0.207 0.00125 2.58 -0.0187 1.22 0.988 0.005 0.981 0.037 15.2 PRS_PLINK_0.000251188643150958 717 Polymyalgia Rheumatica Both 1 3 14 musculoskeletal darkolivegreen 3, 1 1, 0 1, 1 1, 0 1, 0 -0.0375 4530 1 0 0.963 0.929 1.38 -0.00552 82.5 1 0 0.994 0.932 1.09 PRS_PLINK_0.000251188643150958 720 Spinal stenosis Both 1 28 14 musculoskeletal darkolivegreen 28, 1 7, 1 7, 0 7, 0 7, 0 -0.348 0.829 0.674 0.171 0.706 0.0859 4.41 -0.512 2.03 0.801 0.096 0.599 0.00418 241 0.947 2.89 0.743 0.129 2.58 0.00552 2610 -0.701 3.91 0.858 0.067 0.496 1.17e-06 2160 PRS_PLINK_0.000251188643150958 720.1 Spinal stenosis of lumbar region Both 0 24 14 musculoskeletal darkolivegreen 24, 0 6 6 6 6 PRS_PLINK_0.000251188643150958 721 Spondylosis and allied disorders Both 8 42 14 musculoskeletal darkolivegreen 42, 8 11, 1 10, 3 10, 3 11, 1 0.0173 0.61 0.977 0.01 1.02 0.269 4.04 0.643 1.19 0.588 0.23 1.9 0.211 21.6 0.504 1.55 0.745 0.128 1.66 0.000738 998 -0.234 1.33 0.861 0.065 0.791 0.00569 41.6 PRS_PLINK_0.000251188643150958 721.1 Spondylosis without myelopathy Both 7 41 14 musculoskeletal darkolivegreen 41, 7 11, 3 10, 1 10, 2 10, 1 -0.445 0.675 0.509 0.293 0.641 0.145 2.8 -0.593 1.27 0.64 0.194 0.553 0.00238 4.79 -1.88 1.56 0.229 0.64 0.153 0.000331 2.4 -0.78 1.38 0.572 0.243 0.458 3.48e-05 21.9 PRS_PLINK_0.000251188643150958 721.2 Spondylosis with myelopathy Both 0 6 14 musculoskeletal darkolivegreen 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 721.8 Other allied disorders of spine Both 1 4 14 musculoskeletal darkolivegreen 4, 1 1, 0 1, 0 1, 1 1, 0 0.24 8460 1 0 1.27 0.423 4.63 -0.0349 16.3 0.998 0.001 0.966 0.853 18 PRS_PLINK_0.000251188643150958 722 Intervertebral disc disorders Both 4 48 14 musculoskeletal darkolivegreen 48, 4 11, 0 12, 1 12, 2 12, 1 -0.113 0.692 0.87 0.061 0.893 0.0713 8.73 0.529 1.44 0.714 0.146 1.7 0.134 117 -0.808 1.65 0.625 0.204 0.446 0.00407 36 0.484 1.46 0.741 0.13 1.62 0.0685 125 PRS_PLINK_0.000251188643150958 722.1 Displacement of intervertebral disc Both 1 39 14 musculoskeletal darkolivegreen 39, 1 9, 0 10, 0 9, 1 10, 0 -0.294 0.676 0.664 0.178 0.745 0.114 6.86 -0.364 1.87 0.845 0.073 0.695 0.00819 32.8 PRS_PLINK_0.000251188643150958 722.6 Degeneration of intervertebral disc Both 3 35 14 musculoskeletal darkolivegreen 35, 3 9, 1 9, 0 8, 1 9, 1 -0.33 0.89 0.711 0.148 0.719 0.0827 10.3 -0.455 1.52 0.765 0.116 0.635 0.00473 22.1 -0.907 1.95 0.642 0.192 0.404 4.3e-05 42 0.907 2.04 0.657 0.183 2.48 0.00654 11400000 PRS_PLINK_0.000251188643150958 722.7 Intervertebral disc disorder with myelopathy Both 0 6 14 musculoskeletal darkolivegreen 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 722.8 Postlaminectomy syndrome Both 1 9 14 musculoskeletal darkolivegreen 9, 1 3, 1 2, 0 2, 0 2, 0 3.07 5.22 0.557 0.254 21.5 0.0288 346000 0.00611 415 1 0 1.01 0.931 1.09 1.48 4580 1 0 4.39 5.55e-05 152 0.426 27200 1 0 1.53 0.212 13.7 PRS_PLINK_0.000251188643150958 722.9 Other and unspecified disc disorder Both 1 27 14 musculoskeletal darkolivegreen 27, 1 7, 0 7, 1 6, 0 7, 0 -0.163 0.864 0.851 0.07 0.85 0.0477 15.4 0.414 1.62 0.799 0.098 1.51 0.0408 92.4 PRS_PLINK_0.000251188643150958 723 Other disorders of cervical region Both 2 14 14 musculoskeletal darkolivegreen 14, 2 4, 0 3, 2 3, 0 4, 0 -0.221 1.05 0.833 0.079 0.801 0.0543 7.04 1.33 20.9 0.949 0.023 3.77 9.17 9.9 PRS_PLINK_0.000251188643150958 723.1 Torticollis Both 0 6 14 musculoskeletal darkolivegreen 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 724 Other and unspecified disorders of back Both 4 40 14 musculoskeletal darkolivegreen 40, 4 9, 0 10, 2 10, 1 10, 1 -0.133 0.599 0.825 0.084 0.876 0.179 3.24 1.76 1.69 0.299 0.525 5.82 0.387 1.05e+08 0.268 1.57 0.864 0.063 1.31 0.00147 251 0.465 1.33 0.727 0.138 1.59 0.0877 58.6 PRS_PLINK_0.000251188643150958 724.1 Disorders of sacrum Both 3 31 14 musculoskeletal darkolivegreen 31, 3 7, 0 8, 1 7, 1 8, 1 0.271 0.722 0.707 0.15 1.31 0.226 7.87 0.607 1.71 0.722 0.141 1.84 0.0773 318 -0.432 1.69 0.799 0.098 0.649 0.00748 18.1 0.415 1.39 0.765 0.116 1.51 0.146 55.1 PRS_PLINK_0.000251188643150958 724.2 Disorders of coccyx Both 0 7 14 musculoskeletal darkolivegreen 7, 0 2 2 1 2 PRS_PLINK_0.000251188643150958 724.8 Other symptoms referable to back Both 0 14 14 musculoskeletal darkolivegreen 14, 0 4 3 3 4 PRS_PLINK_0.000251188643150958 724.9 Other unspecified back disorders Both 2 15 14 musculoskeletal darkolivegreen 15, 2 4, 0 4, 1 3, 1 4, 0 0.284 1.73 0.87 0.061 1.33 0.0268 40800 -0.215 5430000 1 0 0.807 0.00372 105 -0.419 6370 1 0 0.658 0.0784 1.95 PRS_PLINK_0.000251188643150958 726 Peripheral enthesopathies and allied syndromes Both 23 23 14 musculoskeletal darkolivegreen 23, 23 5, 2 6, 8 5, 8 6, 5 0.121 0.388 0.756 0.122 1.13 0.528 2.35 0.725 1.36 0.594 0.226 2.07 0.22 14.2 3.65 2.6 0.161 0.794 38.4 0.938 83600000 0.053 3.26 0.987 0.006 1.05 0.000733 24100 PRS_PLINK_0.000251188643150958 726.1 Enthesopathy Both 18 23 14 musculoskeletal darkolivegreen 23, 18 5, 1 6, 5 5, 7 6, 5 0.15 0.397 0.705 0.152 1.16 0.534 2.46 -0.549 1.74 0.753 0.123 0.578 0.000931 9.92 2.72 2.36 0.248 0.606 15.2 0.595 192000 0.0832 3.22 0.979 0.009 1.09 0.00126 12000 PRS_PLINK_0.000251188643150958 726.2 Synoviopathy Both 2 6 14 musculoskeletal darkolivegreen 6, 2 2, 0 1, 1 1, 1 2, 0 0.326 1830 1 0 1.39 1.88 0.854 -0.0888 1770 1 0 0.915 0.483 1.58 -0.0101 41.5 1 0 0.99 0.902 1.07 PRS_PLINK_0.000251188643150958 726.3 Bursitis Both 5 10 14 musculoskeletal darkolivegreen 10, 5 2, 0 2, 0 2, 1 3, 4 0.111 0.705 0.875 0.058 1.12 0.135 3.28 -0.394 6430 1 0 0.674 0.541 1.57 0.208 713 1 0 1.23 1.81 3.17 PRS_PLINK_0.000251188643150958 726.4 Calcaneal spur; Exostosis NOS Both 4 8 14 musculoskeletal darkolivegreen 8, 4 2, 0 2, 0 2, 1 2, 3 -0.0508 1.3 0.969 0.014 0.95 0.0304 9.76 -0.78 365 0.998 0.001 0.459 0.000543 297 -0.0731 934 1 0 0.929 0.313 1.79 PRS_PLINK_0.000251188643150958 727 Other disorders of synovium, tendon, and bursa Both 25 22 14 musculoskeletal darkolivegreen 22, 25 5, 2 5, 9 5, 8 6, 6 0.0672 0.363 0.853 0.069 1.07 0.536 2.19 0.198 1.34 0.883 0.054 1.22 0.112 13.2 2.15 1.58 0.174 0.759 8.54 0.771 233 -0.0815 1.68 0.961 0.017 0.922 0.0199 256 PRS_PLINK_0.000251188643150958 727.1 Synovitis and tenosynovitis Both 11 17 14 musculoskeletal darkolivegreen 17, 11 4, 2 4, 4 4, 4 4, 1 -0.0681 0.46 0.882 0.054 0.934 0.397 2.44 -0.907 1.62 0.575 0.24 0.404 0.00694 4.32 1.3 2.18 0.553 0.257 3.65 0.174 212 -1.82 6.42 0.776 0.11 0.162 0.135 0.196 PRS_PLINK_0.000251188643150958 727.2 Bursitis disorders Both 0 2 14 musculoskeletal darkolivegreen 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 727.4 Ganglion and cyst of synovium, tendon, and bursa Both 2 8 14 musculoskeletal darkolivegreen 8, 2 2, 0 2, 0 2, 1 2, 1 -0.447 1.9 0.813 0.09 0.639 0.0289 8.41 -0.0252 846 1 0 0.975 0.709 1.16 0.128 3910 1 0 1.14 0.478 1.22 PRS_PLINK_0.000251188643150958 727.5 Rupture of synovium Both 1 1 14 musculoskeletal darkolivegreen 1, 1 0.0136 19.7 0.999 0 1.01 0.991 4.31 PRS_PLINK_0.000251188643150958 727.6 Rupture of tendon, nontraumatic Both 8 12 14 musculoskeletal darkolivegreen 12, 8 3, 0 3, 3 3, 3 3, 2 1.19 1.25 0.343 0.465 3.27 0.361 3160 0.525 743 0.999 0 1.69 3.13 6.27 0.00124 28.9 1 0 1 0.916 10.3 -0.0459 233 1 0 0.955 0.742 1.4 PRS_PLINK_0.000251188643150958 727.7 Contracture of tendon (sheath) Both 0 4 14 musculoskeletal darkolivegreen 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 727.8 Plica syndrome Both 3 0 14 musculoskeletal darkolivegreen 0, 3 PRS_PLINK_0.000251188643150958 728 Disorders of muscle, ligament, and fascia Both 9 20 14 musculoskeletal darkolivegreen 20, 9 4, 2 5, 4 5, 1 5, 2 -0.152 0.546 0.781 0.107 0.859 0.306 2.24 0.592 1.84 0.747 0.127 1.81 0.111 9.05 -1.97 2.65 0.457 0.34 0.139 0.000303 6.03 -2.59 3.68 0.481 0.318 0.0747 6.74e-07 11.3 PRS_PLINK_0.000251188643150958 728.2 Laxity of ligament or hypermobility syndrome Both 1 1 14 musculoskeletal darkolivegreen 1, 1 -0.0115 74.9 1 0 0.989 0.837 1.38 PRS_PLINK_0.000251188643150958 728.7 Fasciitis Both 11 14 14 musculoskeletal darkolivegreen 14, 11 4, 0 3, 3 3, 3 4, 5 -0.0217 0.74 0.977 0.01 0.979 0.219 3.99 1.12 4.22 0.79 0.102 3.08 3.59 3.54 -1.31 57.5 0.982 0.008 0.27 0.0408 0.312 1.35 2.65 0.609 0.215 3.87 0.0143 436000 PRS_PLINK_0.000251188643150958 728.71 Contracture of palmar fascia [Dupuytren's disease] Both 1 2 14 musculoskeletal darkolivegreen 2, 1 1, 0 0, 1 1, 0 1, 0 0.00969 59.4 1 0 1.01 0.931 1.07 -0.00718 73.1 1 0 0.993 0.892 1.23 PRS_PLINK_0.000251188643150958 729 Other disorders of soft tissues Both 10 20 14 musculoskeletal darkolivegreen 20, 10 4, 1 5, 5 5, 0 5, 4 0.325 0.471 0.49 0.31 1.38 0.636 3.22 1.13 1.6 0.48 0.319 3.1 0.294 52.5 -1.48 2.78 0.595 0.226 0.228 0.00162 8.3 -0.265 2.76 0.924 0.035 0.767 0.00421 66.2 PRS_PLINK_0.000251188643150958 729.7 Nontraumatic compartment syndrome Both 0 1 14 musculoskeletal darkolivegreen 1, 0 PRS_PLINK_0.000251188643150958 731 Osteitis deformans and osteopathies associated with other disorders classified elsewhere Both 0 8 14 musculoskeletal darkolivegreen 8, 0 2 2 2 2 PRS_PLINK_0.000251188643150958 732 Osteochondropathies Both 1 4 14 musculoskeletal darkolivegreen 4, 1 1, 0 1, 0 1, 0 1, 1 -2.58 4560 1 0 0.0759 4.52e-05 183 -0.416 14400 1 0 0.66 0.00262 74 PRS_PLINK_0.000251188643150958 732.1 Juvenile osteochondrosis Both 1 0 14 musculoskeletal darkolivegreen 0, 1 PRS_PLINK_0.000251188643150958 732.7 Osteochondritis dissecans Both 0 2 14 musculoskeletal darkolivegreen 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 733 Other disorders of bone and cartilage Both 5 30 14 musculoskeletal darkolivegreen 30, 5 8, 1 7, 1 7, 1 8, 2 0.652 0.71 0.358 0.446 1.92 0.567 13.5 0.135 1.53 0.93 0.032 1.14 0.05 22.4 -0.0816 1.35 0.952 0.021 0.922 0.0118 15.8 0.22 1.38 0.874 0.059 1.25 0.0246 18 PRS_PLINK_0.000251188643150958 733.2 Cyst of bone Both 0 2 14 musculoskeletal darkolivegreen 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 733.4 Aseptic necrosis of bone Both 1 5 14 musculoskeletal darkolivegreen 5, 1 2, 0 1, 0 1, 1 1, 0 -0.864 21100 1 0 0.421 0.00181 12.4 -0.625 41400 1 0 0.535 5.24e-15 3830000 PRS_PLINK_0.000251188643150958 733.6 Costochondritis Both 1 2 14 musculoskeletal darkolivegreen 2, 1 1, 0 1, 1 1, 0 1, 1 -0.0117 1020 1 0 0.988 0.805 1.2 0.479 6770 1 0 1.61 0.384 1.68 PRS_PLINK_0.000251188643150958 733.8 Malunion and nonunion of fracture Both 0 12 14 musculoskeletal darkolivegreen 12, 0 3 3 3 3 PRS_PLINK_0.000251188643150958 735 Acquired foot deformities Both 11 35 14 musculoskeletal darkolivegreen 35, 11 9, 1 9, 1 8, 3 9, 6 1.24 0.592 0.0371 1.431 3.44 1.25 15.9 1.51 1.81 0.404 0.393 4.51 0.0563 1320 2.84 2.52 0.26 0.585 17.1 0.291 8680000 1.72 1.61 0.283 0.548 5.6 0.394 13600 PRS_PLINK_0.000251188643150958 735.1 Flat foot Both 2 14 14 musculoskeletal darkolivegreen 14, 2 4, 0 3, 1 3, 0 4, 1 0.187 1.73 0.914 0.039 1.21 0.0536 101 0.293 1070000 1 0 1.34 0.448 8.04 -0.418 14700000 1 0 0.659 6.09e-06 76.4 PRS_PLINK_0.000251188643150958 735.2 Acquired toe deformities Both 3 25 14 musculoskeletal darkolivegreen 25, 3 7, 0 6, 0 6, 1 6, 2 0.854 1.3 0.511 0.292 2.35 0.082 528 0.915 1.75 0.6 0.222 2.5 0.0163 2870 1.89 4.9 0.699 0.155 6.63 0.000127 15600 PRS_PLINK_0.000251188643150958 735.21 Hammer toe (acquired) Both 3 21 14 musculoskeletal darkolivegreen 21, 3 6, 0 5, 0 5, 0 5, 3 1.1 1.63 0.498 0.302 3.01 0.0573 653000 1.37 2.3 0.551 0.259 3.94 0.000345 5.29 PRS_PLINK_0.000251188643150958 735.23 Hallux rigidus Both 0 8 14 musculoskeletal darkolivegreen 8, 0 2 2 2 2 PRS_PLINK_0.000251188643150958 735.3 Hallux valgus (Bunion) Both 6 26 14 musculoskeletal darkolivegreen 26, 6 7, 0 6, 0 6, 1 7, 5 1.11 0.694 0.11 0.957 3.03 0.908 316 1.19 2.37 0.616 0.21 3.28 0.0739 289 1.65 1.8 0.359 0.445 5.21 0.261 818 PRS_PLINK_0.000251188643150958 736 Other acquired deformities of limbs Both 7 34 14 musculoskeletal darkolivegreen 34, 7 9, 1 8, 0 8, 1 9, 5 1.28 0.674 0.0584 1.234 3.58 1.26 101 0.0277 1.79 0.988 0.005 1.03 0.00683 142 0.772 1.59 0.627 0.203 2.16 0.0978 570 1.7 1.48 0.248 0.605 5.5 0.481 553 PRS_PLINK_0.000251188643150958 736.2 Acquired deformities of finger Both 1 5 14 musculoskeletal darkolivegreen 5, 1 2, 0 1, 0 1, 0 1, 1 0.333 2590 1 0 1.4 0.0057 8480 0.0677 2.44e+08 1 0 1.07 0.000975 691 PRS_PLINK_0.000251188643150958 736.4 Genu valgum or varum (acquired) Both 0 1 14 musculoskeletal darkolivegreen 1, 0 PRS_PLINK_0.000251188643150958 736.6 Unequal leg length (acquired) Both 0 6 14 musculoskeletal darkolivegreen 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958 737 Curvature of spine Both 2 18 14 musculoskeletal darkolivegreen 18, 2 5, 0 4, 0 4, 0 5, 2 0.6 0.546 0.272 0.566 1.82 0.796 12.4 -0.371 5.03 0.941 0.026 0.69 0.66 0.731 PRS_PLINK_0.000251188643150958 737.1 Kyphosis (acquired) Both 1 7 14 musculoskeletal darkolivegreen 7, 1 2, 0 2, 0 1, 0 2, 1 -0.268 36.9 0.994 0.003 0.765 0.39 2.02 -0.00147 52.3 1 0 0.999 0.981 1.01 PRS_PLINK_0.000251188643150958 737.2 Lordosis (acquired) Both 0 1 14 musculoskeletal darkolivegreen 1, 0 PRS_PLINK_0.000251188643150958 737.3 Kyphoscoliosis and scoliosis Both 1 13 14 musculoskeletal darkolivegreen 13, 1 4, 0 3, 0 3, 0 3, 1 0.499 0.95 0.599 0.222 1.65 0.141 9.76 0.0113 22.2 1 0 1.01 0.0302 1.17 PRS_PLINK_0.000251188643150958 738 Other acquired musculoskeletal deformity Both 3 24 14 musculoskeletal darkolivegreen 24, 3 6, 0 6, 0 6, 1 6, 2 0.32 0.965 0.74 0.131 1.38 0.0126 1720 0.055 2.27 0.981 0.008 1.06 0.0102 352 -0.376 2.86 0.895 0.048 0.686 0.000762 99.7 PRS_PLINK_0.000251188643150958 738.4 Acquired spondylolisthesis Both 0 12 14 musculoskeletal darkolivegreen 12, 0 3 3 3 3 PRS_PLINK_0.000251188643150958 739 Contracture of joint Both 2 10 14 musculoskeletal darkolivegreen 10, 2 3, 0 2, 0 2, 1 3, 1 0.105 1.51 0.945 0.025 1.11 0.118 117 0.0189 3320 1 0 1.02 0.542 1.97 0.323 1390 1 0 1.38 0.704 1.48 PRS_PLINK_0.000251188643150958 740 Osteoarthrosis Both 23 40 14 musculoskeletal darkolivegreen 40, 23 9, 4 10, 7 10, 5 10, 7 0.00656 0.321 0.984 0.007 1.01 0.543 1.83 -0.236 1.01 0.816 0.088 0.79 0.118 4.58 -1.12 1.19 0.343 0.464 0.325 0.0198 2.42 0.0709 1.06 0.947 0.024 1.07 0.164 7.2 PRS_PLINK_0.000251188643150958 740.1 Osteoarthritis; localized Both 12 30 14 musculoskeletal darkolivegreen 30, 12 8, 3 7, 3 7, 3 8, 3 -0.148 0.44 0.737 0.133 0.863 0.364 1.87 -0.77 1.24 0.535 0.272 0.463 0.0359 3.58 -0.58 1.18 0.623 0.205 0.56 0.0568 3.98 0.389 1.17 0.739 0.132 1.48 0.215 13.2 PRS_PLINK_0.000251188643150958 740.11 Osteoarthrosis, localized, primary Both 9 29 14 musculoskeletal darkolivegreen 29, 9 8, 2 7, 3 7, 3 7, 1 -0.686 0.613 0.263 0.58 0.504 0.109 1.43 0.121 1.23 0.921 0.036 1.13 0.0953 12.7 0.218 1.32 0.869 0.061 1.24 0.116 19 -0.447 1.88 0.812 0.09 0.64 0.00835 16 PRS_PLINK_0.000251188643150958 740.12 Osteoarthrosis, localized, secondary Both 1 3 14 musculoskeletal darkolivegreen 3, 1 1, 1 1, 0 1, 0 1, 1 0.0207 6680 1 0 1.02 0.653 55.3 -0.00393 105 1 0 0.996 0.851 1.14 -0.0134 112 1 0 0.987 0.8 1.19 PRS_PLINK_0.000251188643150958 740.2 Osteoarthrosis, generalized Both 4 10 14 musculoskeletal darkolivegreen 10, 4 3, 1 2, 2 2, 0 3, 1 -0.495 1.53 0.747 0.127 0.61 0.0828 5.75 0.0713 497 1 0 1.07 0.648 1.77 0.0226 1390 1 0 1.02 0.223 2.05 0.0123 190 1 0 1.01 1 1.11 PRS_PLINK_0.000251188643150958 740.3 Osteoarthrosis involving more than one site, but not specified as generalized Both 2 1 14 musculoskeletal darkolivegreen 1, 2 26.3 2.09e+10 1 0 2.66e+11 2.85e-35 6.83e+52 PRS_PLINK_0.000251188643150958 740.9 Osteoarthrosis NOS Both 23 40 14 musculoskeletal darkolivegreen 40, 23 9, 4 10, 7 10, 5 10, 7 0.00656 0.321 0.984 0.007 1.01 0.543 1.83 -0.236 1.01 0.816 0.088 0.79 0.118 4.58 -1.12 1.19 0.343 0.464 0.325 0.0198 2.42 0.0709 1.06 0.947 0.024 1.07 0.164 7.2 PRS_PLINK_0.000251188643150958 741 Symptoms and disorders of the joints Both 15 46 14 musculoskeletal darkolivegreen 46, 15 11, 1 11, 3 11, 5 12, 6 0.278 0.314 0.375 0.425 1.32 0.752 2.43 0.0535 1.33 0.968 0.014 1.05 0.0467 13.7 0.853 1.23 0.488 0.311 2.35 0.226 34.3 0.587 1.19 0.623 0.206 1.8 0.214 21.9 PRS_PLINK_0.000251188643150958 741.1 Ankylosis of joint Both 1 3 14 musculoskeletal darkolivegreen 3, 1 1, 0 1, 0 1, 1 1, 0 -0.0091 1140 1 0 0.991 0.706 1.37 -0.00512 45 1 0 0.995 0.931 1.02 PRS_PLINK_0.000251188643150958 741.2 Stiffness of joint Both 2 17 14 musculoskeletal darkolivegreen 17, 2 5, 0 4, 1 4, 0 4, 1 0.127 1.41 0.928 0.032 1.14 0.0025 84 0.151 5.56 0.978 0.01 1.16 0.000168 4040 0.388 18.2 0.983 0.007 1.47 0.938 2.18 PRS_PLINK_0.000251188643150958 741.3 Difficulty in walking Both 1 23 14 musculoskeletal darkolivegreen 23, 1 6, 0 6, 0 5, 1 6, 0 0.247 0.847 0.771 0.113 1.28 0.176 11.4 -0.117 3.73 0.975 0.011 0.89 0.00125 532 PRS_PLINK_0.000251188643150958 741.4 Joint effusions Both 9 32 14 musculoskeletal darkolivegreen 32, 9 7, 1 8, 1 8, 2 8, 5 -0.000991 0.38 0.998 0.001 0.999 0.502 2.03 0.442 1.43 0.758 0.121 1.56 0.131 44.7 -0.0926 1.57 0.953 0.021 0.912 0.013 13.4 -1.15 2.23 0.605 0.218 0.316 1.18e-12 52.7 PRS_PLINK_0.000251188643150958 741.5 Hemarthrosis Both 1 2 14 musculoskeletal darkolivegreen 2, 1 1, 0 1, 1 1, 0 1, 1 0.0136 155 1 0 1.01 0.81 1.35 -0.00895 46.6 1 0 0.991 0.935 1.05 PRS_PLINK_0.000251188643150958 741.6 Villonodular synovitis Both 1 1 14 musculoskeletal darkolivegreen 1, 1 0.00149 299 1 0 1 0.934 1.03 PRS_PLINK_0.000251188643150958 742 Derangement of joint, non-traumatic Both 7 45 14 musculoskeletal darkolivegreen 45, 7 11, 0 11, 2 11, 3 11, 2 0.417 0.434 0.338 0.472 1.52 0.641 5.19 0.882 1.43 0.539 0.269 2.42 0.151 145 1.2 1.69 0.478 0.32 3.3 0.000837 29900 1.24 1.49 0.404 0.394 3.47 0.216 220 PRS_PLINK_0.000251188643150958 742.1 Loose body in joint Both 1 3 14 musculoskeletal darkolivegreen 3, 1 1, 0 1, 0 1, 1 1, 0 0.609 4970 1 0 1.84 0.195 327 -0.00311 14.1 1 0 0.997 0.969 1.03 PRS_PLINK_0.000251188643150958 742.2 Pathological, developmental or recurrent dislocation Both 0 3 14 musculoskeletal darkolivegreen 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 742.8 Articular cartilage disorder Both 1 5 14 musculoskeletal darkolivegreen 5, 1 2, 0 1, 0 1, 0 1, 1 0.00154 58.5 1 0 1 0.664 1.93 -0.268 1030 1 0 0.765 0.703 1.44 PRS_PLINK_0.000251188643150958 742.9 Other derangement of joint Both 5 43 14 musculoskeletal darkolivegreen 43, 5 10, 0 11, 2 10, 2 11, 1 0.124 0.483 0.797 0.098 1.13 0.367 4.42 1.18 1.47 0.423 0.374 3.26 0.23 150 0.874 1.72 0.611 0.214 2.4 0.0312 605 0.482 1.76 0.785 0.105 1.62 0.00282 389 PRS_PLINK_0.000251188643150958 743 Osteoporosis, osteopenia and pathological fracture Both 12 51 14 musculoskeletal darkolivegreen 51, 12 12, 2 13, 5 12, 3 13, 2 -0.0515 0.413 0.901 0.045 0.95 0.407 2.24 0.42 1.07 0.694 0.159 1.52 0.21 16.2 -0.694 1.39 0.617 0.21 0.499 0.00944 7.73 -0.222 1.34 0.868 0.061 0.801 0.00804 11.6 PRS_PLINK_0.000251188643150958 743.1 Osteoporosis Both 6 22 14 musculoskeletal darkolivegreen 22, 6 6, 1 5, 4 5, 0 6, 1 -1.12 0.91 0.217 0.664 0.325 0.0169 1.54 0.915 1.3 0.482 0.317 2.5 0.313 27.4 0.0746 2.2 0.973 0.012 1.08 0.00143 67.6 1.07 5.92 0.856 0.067 2.92 2.47e-06 1.49e+08 PRS_PLINK_0.000251188643150958 743.11 Osteoporosis NOS Both 6 21 14 musculoskeletal darkolivegreen 21, 6 6, 1 5, 4 5, 0 5, 1 -1.12 0.91 0.217 0.664 0.325 0.0169 1.54 0.915 1.3 0.482 0.317 2.5 0.313 27.4 0.0746 2.2 0.973 0.012 1.08 0.00143 67.6 1.07 5.92 0.856 0.067 2.92 2.47e-06 1.49e+08 PRS_PLINK_0.000251188643150958 743.12 Senile osteoporosis Both 0 4 14 musculoskeletal darkolivegreen 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 743.13 Other specified osteoporosis Both 3 4 14 musculoskeletal darkolivegreen 4, 3 1, 0 1, 2 1, 1 1, 0 -0.146 386 1 0 0.864 0.147 15.9 -0.0755 22300 1 0 0.927 0.389 3.2 0.00355 46.1 1 0 1 0.847 1.08 PRS_PLINK_0.000251188643150958 743.2 Pathologic fracture Both 2 8 14 musculoskeletal darkolivegreen 8, 2 2, 0 2, 1 2, 1 2, 0 -1.38 9.47 0.884 0.053 0.252 1.75e-07 117000 -9.75 4130 0.998 0.001 5.81e-05 7.77e-07 7.18e+14 -3.27 5530 1 0 0.0382 4.78e-10 17200000 PRS_PLINK_0.000251188643150958 743.21 Pathologic fracture of vertebrae Both 1 4 14 musculoskeletal darkolivegreen 4, 1 1, 1 1, 0 1, 0 1, 0 -0.00663 1640 1 0 0.993 0.475 1.4 -0.0189 130 1 0 0.981 0.783 1.17 0.00569 206 1 0 1.01 0.919 1.09 -8.28e-05 16.4 1 0 1 0.998 1 PRS_PLINK_0.000251188643150958 743.22 Pathologic fracture of femur Both 0 1 14 musculoskeletal darkolivegreen 1, 0 PRS_PLINK_0.000251188643150958 743.4 Stress fracture Both 2 6 14 musculoskeletal darkolivegreen 6, 2 2, 1 1, 1 1, 0 2, 0 0.133 1960 1 0 1.14 0.453 5.13 -0.000297 429 1 0 1 0.883 1.36 -0.035 557 1 0 0.966 0.733 1.1 0.489 4410 1 0 1.63 0.565 1.79 PRS_PLINK_0.000251188643150958 743.9 Osteopenia or other disorder of bone and cartilage Both 9 46 14 musculoskeletal darkolivegreen 46, 9 11, 2 11, 4 11, 2 12, 1 -0.119 0.43 0.783 0.106 0.888 0.373 2.11 0.537 1.13 0.634 0.198 1.71 0.223 14.9 -0.805 1.37 0.557 0.254 0.447 0.00197 6.12 -0.517 1.4 0.711 0.148 0.596 0.0038 8.94 PRS_PLINK_0.000251188643150958 745 Pain in joint Both 42 22 14 musculoskeletal darkolivegreen 22, 42 5, 5 5, 16 5, 11 6, 10 0.174 0.316 0.582 0.235 1.19 0.666 2.2 0.528 1.12 0.637 0.196 1.69 0.207 13.9 2.28 1.8 0.205 0.688 9.74 0.325 346 -1.48 1.7 0.384 0.416 0.228 0.00134 5.65 PRS_PLINK_0.000251188643150958 747 Cardiac and circulatory congenital anomalies Both 3 23 15 congenital anomalies mediumspringgreen 23, 3 6, 2 6, 1 5, 0 6, 0 -1.51 1 0.131 0.883 0.22 0.0144 1.23 0.413 1.84 0.822 0.085 1.51 0.00381 196 -2.72 6.31 0.666 0.176 0.0657 0.0571 0.0748 -3.52 5.43 0.518 0.286 0.0297 7.29e-10 7870 PRS_PLINK_0.000251188643150958 747.1 Cardiac congenital anomalies Both 3 17 15 congenital anomalies mediumspringgreen 17, 3 5, 2 4, 1 4, 0 4, 0 -2.73 1.78 0.124 0.906 0.0653 0.000523 1.19 1.25 2.5 0.617 0.21 3.5 0.0563 5250 1.78 12.5 0.887 0.052 5.93 4.5 8.58 -4.8 8.1 0.554 0.257 0.00826 0.00603 1090 PRS_PLINK_0.000251188643150958 747.11 Cardiac shunt/ heart septal defect Both 1 9 15 congenital anomalies mediumspringgreen 9, 1 3, 1 2, 0 2, 0 2, 0 0.219 3.82 0.954 0.02 1.24 0.00279 1110 -0.223 3270 1 0 0.8 0.633 2.04 0.858 802 0.999 0 2.36 0.216 41.9 -0.0284 554 1 0 0.972 0.00943 707 PRS_PLINK_0.000251188643150958 747.12 Valvular heart disease/ heart chambers Both 2 4 15 congenital anomalies mediumspringgreen 4, 2 1, 2 1, 0 1, 0 1, 0 0.0919 491 1 0 1.1 0.81 2.18 36.6 120000 1 0 7.57e+15 2.98e-33 5.03e+64 33.6 335000 1 0 3.89e+14 2.63e-12 1.01e+68 13.2 6.5e+08 1 0 519000 2.69e-24 2.11e+36 PRS_PLINK_0.000251188643150958 747.13 Congenital anomalies of great vessels Both 0 3 15 congenital anomalies mediumspringgreen 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 747.2 Congenital anomalies of peripheral vascular system Both 0 7 15 congenital anomalies mediumspringgreen 7, 0 2 2 1 2 PRS_PLINK_0.000251188643150958 748 Anomalies of respiratory system, congenital Both 0 3 15 congenital anomalies mediumspringgreen 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 749 Congenital anomalies of face and neck Both 2 12 15 congenital anomalies mediumspringgreen 12, 2 2, 0 3, 0 3, 2 3, 0 -0.0354 0.613 0.954 0.02 0.965 0.301 4.49 -0.469 2510 1 0 0.626 0.556 2.46 PRS_PLINK_0.000251188643150958 749.1 Cleft palate Both 0 2 15 congenital anomalies mediumspringgreen 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 749.2 Congenital anomalies of skull and face bones Both 0 2 15 congenital anomalies mediumspringgreen 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 750 Digestive congenital anomalies Both 2 13 15 congenital anomalies mediumspringgreen 13, 2 4, 1 3, 0 3, 0 3, 1 -0.829 1.43 0.562 0.25 0.437 0.000859 5.25 -1.05 11600000 1 0 0.349 0.000551 479 0.232 322 0.999 0 1.26 0.494 2.68 0.19 51.6 0.997 0.001 1.21 0.00266 551 PRS_PLINK_0.000251188643150958 750.1 Upper gastrointestinal congenital anomalies Both 0 4 15 congenital anomalies mediumspringgreen 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 750.11 Esophageal atresia/tracheoesophageal fistula Both 0 2 15 congenital anomalies mediumspringgreen 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 750.13 Congenital anomalies of mouth/tongue Both 0 2 15 congenital anomalies mediumspringgreen 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 750.14 Congenital anomalies of esophagus Both 0 1 15 congenital anomalies mediumspringgreen 1, 0 PRS_PLINK_0.000251188643150958 750.2 Lower gastrointestinal congenital anomalies Both 2 11 15 congenital anomalies mediumspringgreen 11, 2 3, 1 3, 0 2, 0 3, 1 -0.375 1.24 0.762 0.118 0.687 0.0172 4.03 -2.74 4890000 1 0 0.0645 1.64e-05 35.2 0.281 10700 1 0 1.32 0.372 6 0.146 69.4 0.998 0.001 1.16 1.04 1.52 PRS_PLINK_0.000251188643150958 750.21 Congenital anomalies of intestine Both 1 6 15 congenital anomalies mediumspringgreen 6, 1 2, 0 1, 0 1, 1 2, 0 0.00725 177 1 0 1.01 0.947 1.13 3.94 6190 0.999 0 51.6 0.000261 3.34e+08 PRS_PLINK_0.000251188643150958 750.22 Congenital anomaly of gallbladder, bile ducts, liver, pancreas Both 1 9 15 congenital anomalies mediumspringgreen 9, 1 3, 1 2, 0 2, 0 2, 0 -0.0959 1.68 0.955 0.02 0.909 0.0458 10.9 -0.0256 1310 1 0 0.975 0.7 1.15 0.373 17600 1 0 1.45 0.272 34.8 -0.013 1370 1 0 0.987 0.505 1.33 PRS_PLINK_0.000251188643150958 751 Genitourinary congenital anomalies Both 8 28 15 congenital anomalies mediumspringgreen 28, 8 7, 0 7, 2 7, 5 7, 1 -0.232 0.444 0.602 0.22 0.793 0.308 1.73 2.48 2.47 0.315 0.502 12 0.302 16900 1.76 1.97 0.372 0.429 5.81 0.255 27900 -0.149 3.24 0.963 0.016 0.862 0.000236 1020 PRS_PLINK_0.000251188643150958 751.1 Congenital anomalies of genital organs Both 3 5 15 congenital anomalies mediumspringgreen 5, 3 2, 0 1, 0 1, 0 1, 3 -0.0291 51.1 1 0 0.971 0.78 1.14 -0.0291 1120 1 0 0.971 0.000408 671 PRS_PLINK_0.000251188643150958 751.11 Congenital anomalies of female genital organs Female 2 3 15 congenital anomalies mediumspringgreen 3, 2 1, 0 1, 0 0, 1 1, 1 0.156 873 1 0 1.17 0.83 2.57 -0.00614 126 1 0 0.994 0.279 4.16 0.484 2760 1 0 1.62 0.414 5.55 PRS_PLINK_0.000251188643150958 751.12 Congenital anomalies of male genital organs Male 0 4 15 congenital anomalies mediumspringgreen 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 751.2 Congenital anomalies of urinary system Both 6 7 15 congenital anomalies mediumspringgreen 7, 6 2, 0 2, 2 1, 3 2, 1 0.527 1.83 0.773 0.112 1.69 0.084 2.08 0.299 5380 1 0 1.35 0.276 1.53 -0.576 468 0.999 0 0.562 0.519 1.47 -3.37 13200000 1 0 0.0343 0.000772 1230000 PRS_PLINK_0.000251188643150958 751.21 Cystic kidney disease Both 2 4 15 congenital anomalies mediumspringgreen 4, 2 1, 0 1, 0 1, 2 1, 0 0.208 1350 1 0 1.23 0.76 1.53 1.19 7860 1 0 3.29 0.337 3.41 PRS_PLINK_0.000251188643150958 751.22 Other specified congenital anomalies of kidney Both 5 3 15 congenital anomalies mediumspringgreen 3, 5 1, 3 1, 1 0, 1 1, 0 -0.0445 68.4 0.999 0 0.956 0.783 1.12 -0.382 4940 1 0 0.683 0.00691 157 0.548 1640 1 0 1.73 0.0217 24.3 0.0293 115 1 0 1.03 0.523 6.73 PRS_PLINK_0.000251188643150958 751.3 Obstructive genitourinary defect Both 1 4 15 congenital anomalies mediumspringgreen 4, 1 1, 0 1, 1 1, 0 1, 0 0.2 5790 1 0 1.22 0.155 186 -0.00418 106 1 0 0.996 0.947 1.04 PRS_PLINK_0.000251188643150958 752 Nervous system congenital anomalies Both 1 15 15 congenital anomalies mediumspringgreen 15, 1 4, 0 4, 1 3, 0 4, 0 0.133 1.25 0.916 0.038 1.14 0.0783 12.4 -0.586 25.8 0.982 0.008 0.557 0.372 0.449 PRS_PLINK_0.000251188643150958 752.1 Neural tube defects Both 0 13 15 congenital anomalies mediumspringgreen 13, 0 4 3 3 3 PRS_PLINK_0.000251188643150958 752.11 Spina bifida Both 0 2 15 congenital anomalies mediumspringgreen 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 752.2 Other specified congenital anomalies of nervous system Both 0 4 15 congenital anomalies mediumspringgreen 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 753 Congenital anomalies of the eye Both 1 8 15 congenital anomalies mediumspringgreen 8, 1 2, 0 2, 1 2, 0 2, 0 -0.181 134 0.999 0 0.834 1.9 2.72 -1.32 4270 1 0 0.268 0.000338 146 PRS_PLINK_0.000251188643150958 753.1 Congenital cataract and lens anomalies Both 0 1 15 congenital anomalies mediumspringgreen 1, 0 PRS_PLINK_0.000251188643150958 753.2 Congenital anomalies of posterior segment of eye Both 0 3 15 congenital anomalies mediumspringgreen 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 754 Congenital musculoskeletal deformities of spine Both 1 11 15 congenital anomalies mediumspringgreen 11, 1 3, 0 3, 1 2, 0 3, 0 -0.248 8.46 0.977 0.01 0.78 0.00509 126 -0.152 1710 1 0 0.859 0.239 4.95 PRS_PLINK_0.000251188643150958 754.1 Lumbosacral spondylolysis, congenital Both 1 2 15 congenital anomalies mediumspringgreen 2, 1 1, 0 1, 1 1, 0 1, 1 -0.0376 213 1 0 0.963 0.932 1.1 -0.0125 36.9 1 0 0.988 0.96 1.04 PRS_PLINK_0.000251188643150958 754.2 Spondylolisthesis, congenital Both 0 5 15 congenital anomalies mediumspringgreen 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 755 Congenital anomalies of limbs Both 1 14 15 congenital anomalies mediumspringgreen 14, 1 4, 0 3, 0 3, 0 4, 1 0.357 0.956 0.709 0.15 1.43 0.2 11.9 0.4 1280 1 0 1.49 0.0118 26800 PRS_PLINK_0.000251188643150958 755.1 Congenital deformities of feet Both 1 9 15 congenital anomalies mediumspringgreen 9, 1 3, 0 2, 0 2, 0 2, 1 -2.4e-13 3.42 1 0 1 0.0106 140 -0.00757 593 1 0 0.992 0.741 1.3 PRS_PLINK_0.000251188643150958 755.6 Other congenital anomalies of lower limb, including pelvic girdle Both 0 4 15 congenital anomalies mediumspringgreen 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 755.61 Congenital hip dysplasia and deformity Both 0 2 15 congenital anomalies mediumspringgreen 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 756 Other congenital musculoskeletal anomalies Both 2 17 15 congenital anomalies mediumspringgreen 17, 2 4, 0 4, 2 4, 0 4, 0 -0.127 0.599 0.832 0.08 0.88 0.307 3.83 -0.172 23.8 0.994 0.003 0.842 0.00283 247 PRS_PLINK_0.000251188643150958 756.2 Pectus and other congenital anomalies of ribs/sternum Both 0 1 15 congenital anomalies mediumspringgreen 1, 0 PRS_PLINK_0.000251188643150958 756.3 Congenital anomalies of muscle, tendon, fascia, and connective tissue Both 0 2 15 congenital anomalies mediumspringgreen 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 756.5 Congenital osteodystrophies Both 1 11 15 congenital anomalies mediumspringgreen 11, 1 3, 0 3, 1 2, 0 3, 0 0.0378 1.33 0.977 0.01 1.04 0.108 8.15 -0.0183 432 1 0 0.982 0.641 1.45 PRS_PLINK_0.000251188643150958 757 Congenital anomalies of the integument Both 1 4 15 congenital anomalies mediumspringgreen 4, 1 1, 0 1, 0 1, 0 1, 1 -1.18 2960 1 0 0.308 0.00159 56.7 -12.9 54600 1 0 2.55e-06 4.41e-20 9.8e+11 PRS_PLINK_0.000251188643150958 758 Chromosomal anomalies and genetic disorders Both 1 2 15 congenital anomalies mediumspringgreen 2, 1 1, 1 1, 0 1, 1 1, 0 2.95 1.34e+09 1 0 19.1 0.000196 1040000 0.241 13800 1 0 1.27 0.45 1.89 PRS_PLINK_0.000251188643150958 758.1 Chromosomal anomalies Both 1 0 15 congenital anomalies mediumspringgreen 0, 1 PRS_PLINK_0.000251188643150958 759 Other and unspecified congenital anomalies Both 0 3 15 congenital anomalies mediumspringgreen 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 760 Back pain Both 25 39 17 symptoms purple 39, 25 9, 3 10, 11 9, 4 10, 7 0.0656 0.285 0.818 0.087 1.07 0.631 1.81 0.391 0.906 0.666 0.176 1.48 0.303 7.74 0.00345 1.23 0.998 0.001 1 0.109 7.98 -0.345 1.29 0.789 0.103 0.709 0.00959 7.13 PRS_PLINK_0.000251188643150958 761 Cervicalgia Both 15 48 17 symptoms purple 48, 15 11, 1 12, 7 12, 3 12, 4 0.121 0.332 0.715 0.146 1.13 0.597 2.12 0.796 1.08 0.463 0.335 2.22 0.333 20.9 -0.78 1.69 0.644 0.191 0.458 0.00179 12.3 0.323 1.24 0.794 0.1 1.38 0.0193 14.2 PRS_PLINK_0.000251188643150958 763 Thoracic or lumbosacral neuritis or radiculitis, unspecified Both 2 39 17 symptoms purple 39, 2 9, 0 10, 2 9, 0 10, 0 -0.165 0.594 0.781 0.108 0.848 0.238 3.28 2.86 2.02 0.156 0.805 17.4 0.682 192000 PRS_PLINK_0.000251188643150958 764 Sciatica Both 2 38 17 symptoms purple 38, 2 10, 2 9, 0 9, 0 10, 0 -0.535 0.75 0.476 0.323 0.586 0.0755 3.16 -0.355 1.81 0.844 0.073 0.701 0.00217 41.8 -0.287 1.43 0.841 0.075 0.751 0.00931 33800 -0.721 2.06 0.727 0.139 0.486 0.000552 1170 PRS_PLINK_0.000251188643150958 765 Cervical radiculitis Both 3 25 17 symptoms purple 25, 3 6, 1 6, 0 6, 0 6, 2 0.195 0.678 0.774 0.111 1.22 0.291 11.2 -1.07 3.44 0.757 0.121 0.344 7.32e-06 543 -2.06 3.85 0.593 0.227 0.128 4.44e-05 43 -0.917 2.51 0.715 0.146 0.4 0.000249 1770 PRS_PLINK_0.000251188643150958 766 Neuralgia, neuritis, and radiculitis NOS Both 6 48 17 symptoms purple 48, 6 11, 3 12, 2 12, 0 12, 1 0.117 0.442 0.792 0.101 1.12 0.469 3.07 0.303 1.09 0.78 0.108 1.35 0.164 13.3 -1.51 1.35 0.262 0.582 0.22 9.53e-09 2 -0.45 1.35 0.738 0.132 0.638 0.0302 128 PRS_PLINK_0.000251188643150958 767 Cervicocranial/Cervicobrachial syndrome Both 0 1 17 symptoms purple 1, 0 PRS_PLINK_0.000251188643150958 769 Nonallopathic lesions NEC Both 2 20 17 symptoms purple 20, 2 4, 0 5, 1 5, 0 5, 1 0.0764 0.767 0.921 0.036 1.08 0.23 9.69 2.19 3.96 0.581 0.236 8.91 0.166 2410 -0.0169 32.8 1 0 0.983 0.014 69 PRS_PLINK_0.000251188643150958 770 Myalgia and myositis unspecified Both 11 47 17 symptoms purple 47, 11 11, 8 12, 2 11, 1 12, 0 -0.736 0.479 0.125 0.904 0.479 0.17 1.18 -1.13 1.01 0.264 0.579 0.324 0.0387 2.24 -2.9 1.73 0.093 1.031 0.0549 7.74e-07 0.787 -3.4 2 0.0886 1.053 0.0332 7.95e-06 0.858 PRS_PLINK_0.000251188643150958 771 Musculoskeletal symptoms referable to limbs Both 6 44 17 symptoms purple 44, 6 10, 1 11, 2 11, 0 11, 3 0.383 0.618 0.536 0.271 1.47 0.421 6.36 1.31 1.31 0.319 0.496 3.7 0.397 69.2 0.088 1.54 0.954 0.02 1.09 0.022 25.8 1.01 1.49 0.499 0.302 2.75 0.136 70.3 PRS_PLINK_0.000251188643150958 771.1 Swelling of limb Both 11 43 17 symptoms purple 43, 11 10, 2 11, 4 10, 0 11, 5 0.245 0.412 0.551 0.259 1.28 0.585 2.85 2.67 1.98 0.176 0.754 14.4 0.591 12100 0.61 1.77 0.731 0.136 1.84 0.0246 283 1.65 1.46 0.258 0.589 5.22 0.413 190 PRS_PLINK_0.000251188643150958 771.2 Cramp of limb Both 1 18 17 symptoms purple 18, 1 5, 0 4, 0 4, 0 5, 1 0.655 1.47 0.655 0.184 1.92 0.0832 189 1.24 3.3 0.708 0.15 3.45 0.0276 3270 PRS_PLINK_0.000251188643150958 772 Symptoms of the muscles Both 6 23 17 symptoms purple 23, 6 6, 1 6, 4 5, 0 6, 1 -0.291 0.726 0.689 0.162 0.748 0.159 3 0.85 1.54 0.58 0.236 2.34 0.218 32.4 -0.666 2.49 0.789 0.103 0.514 0.00777 22 0.528 2.92 0.856 0.067 1.7 0.0196 4530 PRS_PLINK_0.000251188643150958 772.1 Muscular wasting and disuse atrophy Both 1 9 17 symptoms purple 9, 1 3, 0 2, 0 2, 0 2, 1 -0.616 4.53 0.892 0.05 0.54 0.000415 283 -0.187 79.5 0.998 0.001 0.829 0.0548 9.88 PRS_PLINK_0.000251188643150958 772.2 Spasm of muscle Both 3 31 17 symptoms purple 31, 3 7, 2 8, 0 7, 1 8, 0 0.527 0.839 0.53 0.276 1.69 0.214 35000 -0.39 2.28 0.864 0.063 0.677 0.0143 154 -0.575 3.47 0.868 0.061 0.563 0.000658 14.8 0.0758 2.3 0.974 0.012 1.08 0.00574 78.1 PRS_PLINK_0.000251188643150958 772.3 Muscle weakness Both 4 27 17 symptoms purple 27, 4 7, 1 7, 1 6, 2 7, 0 0.212 0.902 0.814 0.089 1.24 0.039 7.84 1.14 1.98 0.564 0.249 3.13 0.117 337000 0.185 1.77 0.917 0.038 1.2 0.0013 41 -0.733 3.33 0.826 0.083 0.481 0.00079 199 PRS_PLINK_0.000251188643150958 772.4 Rhabdomyolysis Both 2 0 17 symptoms purple 0, 2 PRS_PLINK_0.000251188643150958 772.6 Facial weakness Both 0 3 17 symptoms purple 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 780 Hypothermia/Chills Both 1 8 17 symptoms purple 8, 1 2, 0 2, 1 2, 0 2, 0 -1.14 5.25 0.828 0.082 0.32 0.114 0.865 -0.425 3900 1 0 0.654 0.619 360000 PRS_PLINK_0.000251188643150958 781 Symptoms involving nervous and musculoskeletal systems Both 4 31 17 symptoms purple 31, 4 8, 0 8, 2 7, 2 8, 0 -1.02 0.998 0.307 0.513 0.36 0.00069 654 1.11 2.06 0.591 0.228 3.03 0.0368 5300000 -0.0524 2.4 0.983 0.008 0.949 0.0127 253 PRS_PLINK_0.000251188643150958 782.3 Edema Both 12 40 17 symptoms purple 40, 12 9, 1 10, 6 10, 0 10, 5 0.354 0.42 0.4 0.398 1.42 0.654 3.28 1.76 1.35 0.192 0.718 5.82 0.594 202 -1.36 1.77 0.442 0.355 0.256 0.00108 7.27 0.476 1.36 0.727 0.139 1.61 0.115 22.7 PRS_PLINK_0.000251188643150958 782.6 Pallor and flushing Both 2 10 17 symptoms purple 10, 2 3, 1 2, 0 2, 0 3, 1 0.177 1.58 0.911 0.041 1.19 0.00235 47.4 0.172 1700 1 0 1.19 0.241 8.07 0.0466 1920 1 0 1.05 0.44 2.6 -0.147 592 1 0 0.864 0.15 1.47 PRS_PLINK_0.000251188643150958 783 Fever of unknown origin Both 10 52 17 symptoms purple 52, 10 12, 4 13, 2 13, 1 13, 3 -0.425 0.404 0.293 0.533 0.654 0.265 1.38 -0.446 1.02 0.662 0.179 0.64 0.0898 4.09 -1.05 1.19 0.382 0.418 0.352 0.0162 2.75 -0.309 0.973 0.751 0.125 0.734 0.0856 4.21 PRS_PLINK_0.000251188643150958 785 Abdominal pain Both 30 34 17 symptoms purple 34, 30 8, 4 8, 11 8, 4 9, 11 0.193 0.295 0.513 0.29 1.21 0.717 2.16 0.825 1.01 0.416 0.381 2.28 0.394 16.4 -1.19 1.34 0.375 0.427 0.305 0.0221 2.83 1.56 1.16 0.178 0.75 4.76 0.734 76.4 PRS_PLINK_0.000251188643150958 788 Syncope and collapse Both 5 49 17 symptoms purple 49, 5 12, 0 12, 3 12, 0 12, 2 -0.161 0.522 0.757 0.121 0.851 0.271 2.47 3.31 2.02 0.101 0.994 27.5 0.927 328000 -1.06 1.87 0.572 0.243 0.348 0.00093 37.3 PRS_PLINK_0.000251188643150958 789 Nausea and vomiting Both 18 46 17 symptoms purple 46, 18 11, 3 11, 8 11, 3 12, 4 -0.02 0.296 0.946 0.024 0.98 0.559 1.68 1.03 0.985 0.295 0.53 2.8 0.513 21.6 0.756 1.25 0.545 0.264 2.13 0.215 29.6 0.821 1.25 0.51 0.293 2.27 0.21 50.5 PRS_PLINK_0.000251188643150958 789.1 Persistent vomiting Both 2 10 17 symptoms purple 10, 2 3, 1 2, 1 2, 0 3, 0 -2.69 2.79 0.336 0.474 0.068 0.000147 3.21 2.6 44900000 1 0 13.5 7.92e-08 2.53e+08 0.0248 460 1 0 1.03 0.697 3.63 0.0216 519 1 0 1.02 0.748 3.08 PRS_PLINK_0.000251188643150958 790 Nonspecific findings on examination of blood Both 16 27 17 symptoms purple 27, 16 7, 6 7, 1 6, 4 7, 5 0.42 0.681 0.538 0.269 1.52 0.256 3540 -0.558 1.82 0.759 0.12 0.572 0.00443 94.7 0.117 1.61 0.942 0.026 1.12 0.00675 342 -0.244 1.51 0.871 0.06 0.784 0.0311 102 PRS_PLINK_0.000251188643150958 790.1 Elevated sedimentation rate Both 1 4 17 symptoms purple 4, 1 1, 0 1, 0 1, 1 1, 0 0.662 8470 1 0 1.94 0.00203 11400 -0.611 7410 1 0 0.543 0.512 1.87 PRS_PLINK_0.000251188643150958 790.6 Other abnormal blood chemistry Both 22 40 17 symptoms purple 40, 22 9, 4 10, 7 10, 5 10, 6 -0.0437 0.326 0.893 0.049 0.957 0.52 1.75 1.6 1.49 0.285 0.545 4.93 0.403 234 3.47 2.59 0.18 0.745 32.2 0.193 30900 -0.374 1.28 0.77 0.113 0.688 0.0535 6.88 PRS_PLINK_0.000251188643150958 790.8 Elevated C-reactive protein (CRP) Both 0 5 17 symptoms purple 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 790.9 Abnormal arterial blood gases Both 0 2 17 symptoms purple 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 791 Gangrene Both 0 13 17 symptoms purple 13, 0 4 3 3 3 PRS_PLINK_0.000251188643150958 792 Abnormal Papanicolaou smear of cervix and cervical HPV Female 6 15 11 genitourinary black 15, 6 3, 1 4, 2 3, 2 4, 1 0.116 0.624 0.852 0.069 1.12 0.4 3.38 2.04 4.21 0.629 0.202 7.67 0.0231 15500 -0.886 103 0.993 0.003 0.412 0.0208 0.425 -1.48 48.8 0.976 0.011 0.229 3.65e-11 0.325 PRS_PLINK_0.000251188643150958 792.1 Papanicolaou smear of cervix or vagina with atypical squamous cells Female 4 7 11 genitourinary black 7, 4 1, 0 2, 2 1, 2 2, 0 -2.41 3.62 0.505 0.297 0.0898 5.43e-06 11.9 -0.774 1930 1 0 0.461 0.000152 2650 6.88 18600 1 0 977 8.11e-47 1.93e+54 PRS_PLINK_0.000251188643150958 794 Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc) Both 0 5 17 symptoms purple 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 795 Other and nonspecific abnormal cytological, histological and immunological findings Both 3 27 17 symptoms purple 27, 3 6, 1 7, 2 6, 0 7, 0 -0.774 0.762 0.31 0.508 0.461 0.0146 1.8 -0.161 1.57 0.919 0.037 0.851 0.0589 11.7 -1.65 2.99 0.581 0.236 0.192 0.000896 22.5 -0.206 2.17 0.924 0.034 0.814 0.0113 69.5 PRS_PLINK_0.000251188643150958 795.8 Abnormal tumor markers Both 1 13 17 symptoms purple 13, 1 4, 1 3, 0 3, 0 3, 0 -0.529 1.75 0.763 0.118 0.589 0.00812 15.6 -0.831 5620000 1 0 0.435 0.137 1.03 -1.37 2100 0.999 0 0.253 0.00648 0.0287 -0.467 4890 1 0 0.627 0.0638 6.12 PRS_PLINK_0.000251188643150958 795.81 Elevated carcinoembryonic antigen [CEA] Both 0 1 17 symptoms purple 1, 0 PRS_PLINK_0.000251188643150958 795.82 Elevated cancer antigen 125 [CA 125] Both 0 2 17 symptoms purple 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 796 Elevated prostate specific antigen [PSA] Male 2 10 11 genitourinary black 10, 2 3, 1 2, 0 2, 0 3, 1 0.664 2.27 0.77 0.113 1.94 0.0156 323 -0.944 1210 0.999 0 0.389 0.16 2.47 -0.785 10400 1 0 0.456 0.00358 19.8 -2.05 279 0.994 0.003 0.128 0.247 0.911 PRS_PLINK_0.000251188643150958 797 Shock Both 0 10 17 symptoms purple 10, 0 3 2 2 3 PRS_PLINK_0.000251188643150958 797.1 Cardiogenic shock Both 0 4 17 symptoms purple 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 798 Malaise and fatigue Both 25 39 17 symptoms purple 39, 25 9, 9 10, 7 9, 6 10, 3 -0.248 0.335 0.459 0.338 0.78 0.395 1.42 0.251 0.849 0.767 0.115 1.29 0.285 6.39 -0.158 0.929 0.865 0.063 0.854 0.163 4.32 -1.97 1.44 0.169 0.771 0.139 2.03e-05 1.73 PRS_PLINK_0.000251188643150958 798.1 Chronic fatigue syndrome Both 4 20 17 symptoms purple 20, 4 5, 2 5, 1 5, 1 5, 0 -1.72 1.1 0.117 0.931 0.179 0.00518 1.07 0.0243 2.23 0.991 0.004 1.02 0.0291 38.2 -6.17 12.7 0.628 0.202 0.00208 0.00138 1.2e+07 1.85 6.53 0.777 0.11 6.37 0.000574 1430000 PRS_PLINK_0.000251188643150958 800 Fracture of lower limb Both 6 28 18 injuries & poisonings gray50 28, 6 7, 2 7, 2 7, 0 7, 2 -0.00899 0.45 0.984 0.007 0.991 0.384 2.26 2.54 2 0.204 0.69 12.7 0.408 16.8 -1.92 1.99 0.335 0.475 0.147 0.000193 2.42 0.73 1.92 0.704 0.152 2.08 0.0684 1530 PRS_PLINK_0.000251188643150958 800.1 Fracture of neck of femur Both 0 7 18 injuries & poisonings gray50 7, 0 2 2 1 2 PRS_PLINK_0.000251188643150958 800.2 Fracture of unspecified part of femur Both 2 3 18 injuries & poisonings gray50 3, 2 1, 0 1, 0 1, 2 1, 0 -0.0116 1200 1 0 0.988 0.611 1.35 0.531 1.08e+08 1 0 1.7 0.0244 86.4 PRS_PLINK_0.000251188643150958 800.3 Fracture of tibia and fibula Both 4 15 18 injuries & poisonings gray50 15, 4 4, 3 4, 0 3, 0 4, 1 -0.287 0.612 0.639 0.194 0.751 0.263 1.88 -0.144 3.51 0.967 0.015 0.865 0.00307 6270 -0.586 13.3 0.965 0.016 0.556 0.39 0.42 -0.717 1.84 0.696 0.157 0.488 0.0149 37.3 PRS_PLINK_0.000251188643150958 800.4 Fracture of patella Both 2 3 18 injuries & poisonings gray50 3, 2 1, 1 1, 0 1, 1 1, 1 -0.0513 256 1 0 0.95 0.272 1.18 0.0041 56.8 1 0 1 0.585 1.18 0.274 1670 1 0 1.31 0.803 1.32 PRS_PLINK_0.000251188643150958 801 Fracture of ankle and foot Both 7 36 18 injuries & poisonings gray50 36, 7 9, 2 9, 3 9, 0 9, 2 -0.265 0.431 0.538 0.269 0.767 0.278 1.61 0.933 1.37 0.496 0.304 2.54 0.261 71.1 -1.37 1.77 0.438 0.359 0.253 0.000263 4.54 -0.97 1.46 0.506 0.296 0.379 0.000747 3.99 PRS_PLINK_0.000251188643150958 801.1 Fracture of foot Both 2 14 18 injuries & poisonings gray50 14, 2 4, 1 3, 1 3, 0 4, 0 -0.488 0.904 0.59 0.229 0.614 0.0316 2.23 1.82 15.7 0.907 0.042 6.19 4.95 7.44 0.464 4990 1 0 1.59 0.334 13.4 -1.89 85.1 0.982 0.008 0.15 8e-15 0.176 PRS_PLINK_0.000251188643150958 802 Fracture of pelvis Both 0 5 18 injuries & poisonings gray50 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 803 Fracture of upper limb Both 6 23 18 injuries & poisonings gray50 23, 6 5, 1 6, 1 5, 2 6, 2 0.136 0.441 0.759 0.12 1.15 0.516 3.67 -0.688 2.36 0.771 0.113 0.503 0.00196 25.1 1.81 2.44 0.456 0.341 6.14 0.159 1200 -1.39 3.89 0.72 0.142 0.249 7.69e-05 119 PRS_PLINK_0.000251188643150958 803.1 Fracture of humerus Both 2 6 18 injuries & poisonings gray50 6, 2 2, 2 1, 0 1, 0 2, 0 -0.0213 635 1 0 0.979 0.725 1.26 -2.26 4930 1 0 0.104 1.01e-11 32500000 -0.0665 1050 1 0 0.936 0.0836 16 -0.045 677 1 0 0.956 0.104 2.6 PRS_PLINK_0.000251188643150958 803.2 Fracture of radius and ulna Both 4 14 18 injuries & poisonings gray50 14, 4 3, 1 3, 0 3, 0 4, 3 0.189 0.822 0.818 0.087 1.21 0.254 3.65 -0.541 5930 1 0 0.582 7.49e-05 30600 -0.649 1010 0.999 0 0.523 0.719 0.746 0.259 4240 1 0 1.3 1.5e-09 43 PRS_PLINK_0.000251188643150958 803.21 Colles' fracture Both 0 4 18 injuries & poisonings gray50 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 803.3 Fracture of clavicle or scapula Both 0 2 18 injuries & poisonings gray50 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 804 Fracture of hand or wrist Both 8 26 18 injuries & poisonings gray50 26, 8 7, 1 6, 0 6, 6 7, 1 -0.295 0.558 0.597 0.224 0.745 0.168 1.79 0.91 2.88 0.752 0.124 2.48 0.000665 1210 4.43 2.71 0.102 0.992 83.6 1.35 35500000 -1.99 2.46 0.418 0.379 0.137 5.32e-06 5.36 PRS_PLINK_0.000251188643150958 805 Fracture of vertebral column without mention of spinal cord injury Both 2 8 18 injuries & poisonings gray50 8, 2 2, 0 2, 1 2, 0 2, 1 1.54 4.09 0.707 0.15 4.65 0.0237 7180 0.455 8350 1 0 1.58 0.000148 4210 -0.151 8540 1 0 0.86 0.0956 5.79 PRS_PLINK_0.000251188643150958 807 Fracture of ribs Both 2 8 18 injuries & poisonings gray50 8, 2 2, 0 2, 0 2, 1 2, 1 0.268 1.53 0.861 0.065 1.31 0.19 9.84 -0.0755 2900 1 0 0.927 0.809 3.18 -0.0482 1800 1 0 0.953 0.478 2.2 PRS_PLINK_0.000251188643150958 809 Fracture of unspecified bones Both 6 37 18 injuries & poisonings gray50 37, 6 9, 1 9, 2 9, 1 9, 2 0.864 0.751 0.25 0.602 2.37 0.434 19.9 0.893 1.55 0.564 0.248 2.44 0.00192 82.2 0.777 2.11 0.713 0.147 2.18 0.0327 2330 0.876 2.06 0.671 0.173 2.4 0.0437 92.9 PRS_PLINK_0.000251188643150958 816 Cerebral laceration and contusion Both 0 3 18 injuries & poisonings gray50 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 817 Concussion Both 2 22 18 injuries & poisonings gray50 22, 2 6, 1 5, 0 5, 1 6, 0 -0.123 0.637 0.847 0.072 0.884 0.114 3.47 1.36 3.25 0.674 0.171 3.91 1.48e-06 2230 -0.557 5.57 0.92 0.036 0.573 1.27e-05 6940 -1.61 3.85 0.677 0.169 0.201 3.49e-07 115 PRS_PLINK_0.000251188643150958 818 Intracranial hemorrhage (injury) Both 0 5 18 injuries & poisonings gray50 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 818.1 Subdural hemorrhage (injury) Both 0 1 18 injuries & poisonings gray50 1, 0 PRS_PLINK_0.000251188643150958 818.2 Subarachnoid hemorrhage (injury) Both 0 4 18 injuries & poisonings gray50 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 819 Skull and face fracture and other intercranial injury Both 4 37 18 injuries & poisonings gray50 37, 4 10, 1 9, 2 9, 0 9, 1 0.194 0.545 0.722 0.141 1.21 0.214 9.3 1.38 2.02 0.492 0.308 3.99 0.0891 19400 -0.105 1.53 0.945 0.025 0.9 0.00613 13.6 -1 1.85 0.589 0.23 0.368 0.000203 10.7 PRS_PLINK_0.000251188643150958 830 Dislocation Both 12 42 18 injuries & poisonings gray50 42, 12 10, 0 10, 4 10, 3 11, 5 0.128 0.334 0.702 0.154 1.14 0.609 2.12 1.47 1.67 0.38 0.42 4.34 0.0646 1630 0.804 1.68 0.633 0.199 2.23 0.00154 3690 0.19 1.86 0.919 0.037 1.21 0.00189 238 PRS_PLINK_0.000251188643150958 835 Internal derangement of knee Both 5 27 18 injuries & poisonings gray50 27, 5 7, 0 7, 2 6, 1 7, 2 0.0555 0.504 0.912 0.04 1.06 0.36 2.7 1.58 2.16 0.462 0.335 4.88 0.0445 1590 1.95 2.34 0.403 0.395 7.06 0.264 474 1.48 2.21 0.504 0.298 4.39 0.012 358 PRS_PLINK_0.000251188643150958 836 Traumatic arthropathy Both 2 6 18 injuries & poisonings gray50 6, 2 2, 0 1, 0 1, 0 2, 2 0.288 65.4 0.996 0.002 1.33 0.322 13.3 0.108 1010 1 0 1.11 0.658 2.02 PRS_PLINK_0.000251188643150958 840 Sprains and strains Both 19 43 18 injuries & poisonings gray50 43, 19 10, 1 11, 7 10, 4 11, 7 0.231 0.306 0.451 0.346 1.26 0.73 2.27 1.8 1.15 0.117 0.932 6.08 0.91 68.2 -0.575 1.62 0.722 0.141 0.563 0.00119 16.4 0.926 1.27 0.465 0.333 2.53 0.278 37.8 PRS_PLINK_0.000251188643150958 840.1 Muscle/tendon sprain Both 2 3 18 injuries & poisonings gray50 3, 2 1, 0 1, 1 1, 1 1, 0 -3.49 1.18e+08 1 0 0.0305 4.4e-10 4.2e+07 -0.0114 41.3 1 0 0.989 0.961 1.04 0.0261 29.4 0.999 0 1.03 0.935 1.21 PRS_PLINK_0.000251188643150958 840.2 Rotator cuff (capsule) sprain Both 7 16 18 injuries & poisonings gray50 16, 7 4, 0 4, 3 4, 2 4, 2 0.244 0.868 0.779 0.109 1.28 0.312 6.55 2.64 3.43 0.442 0.355 14 1.11 197 0.693 9.34 0.941 0.026 2 1.86 2.13 1.19 30.2 0.969 0.014 3.28 0.221 3.35 PRS_PLINK_0.000251188643150958 840.3 Joint/ligament sprain Both 6 40 18 injuries & poisonings gray50 40, 6 9, 0 10, 2 10, 1 10, 3 0.192 0.392 0.624 0.205 1.21 0.597 2.83 1.44 1.6 0.371 0.431 4.21 0.125 616 0.369 1.71 0.83 0.081 1.45 0.0106 591 0.851 1.57 0.588 0.231 2.34 0.062 15400 PRS_PLINK_0.000251188643150958 841 Sprains and strains of back and neck Both 1 26 18 injuries & poisonings gray50 26, 1 6, 0 6, 0 6, 0 7, 1 -0.0155 0.592 0.979 0.009 0.985 0.182 3.82 2.5 7.03 0.722 0.141 12.2 1.12e-07 74900000 PRS_PLINK_0.000251188643150958 842 Other sprains and strains Both 4 23 18 injuries & poisonings gray50 23, 4 6, 1 6, 0 5, 0 6, 3 0.132 0.571 0.817 0.088 1.14 0.266 4.11 -1.07 2.2 0.626 0.203 0.343 0.00682 28.4 0.571 2.92 0.845 0.073 1.77 0.00435 5650 -0.314 2.26 0.89 0.051 0.73 0.00462 76.3 PRS_PLINK_0.000251188643150958 850 Hemorrhage or hematoma complicating a procedure Both 2 24 18 injuries & poisonings gray50 24, 2 6, 1 6, 0 6, 0 6, 1 -0.75 0.802 0.35 0.456 0.472 0.00978 2.52 0.462 7.66 0.952 0.021 1.59 0.00382 1130 0.556 2.42 0.818 0.087 1.74 0.033 766 -1.56 2.99 0.601 0.221 0.21 1.39e-05 10900 PRS_PLINK_0.000251188643150958 851 Complications of transplants and reattached limbs Both 2 34 18 injuries & poisonings gray50 34, 2 9, 2 8, 0 8, 0 9, 0 -1.77 1.23 0.151 0.82 0.171 0.000263 2.03 -0.161 3.03 0.958 0.019 0.852 5.86e-07 1450 -0.498 1.93 0.797 0.099 0.608 0.000827 52.7 -0.53 1.59 0.739 0.132 0.588 0.0011 9.42 PRS_PLINK_0.000251188643150958 853 Complication of colostomy or enterostomy Both 0 3 18 injuries & poisonings gray50 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 854 Complications of cardiac/vascular device, implant, and graft Both 4 25 18 injuries & poisonings gray50 25, 4 7, 3 6, 1 6, 0 6, 0 -0.826 0.674 0.22 0.658 0.438 0.0726 1.45 1.11 2.01 0.582 0.235 3.02 0.098 107 0.136 1.91 0.943 0.025 1.15 0.0197 164 -1.05 1.93 0.584 0.233 0.349 0.0019 23.8 PRS_PLINK_0.000251188643150958 855 Complication of nervous system device, implant, and graft Both 1 2 18 injuries & poisonings gray50 2, 1 1, 1 1, 0 1, 1 1, 0 -0.0241 107 1 0 0.976 0.884 6.51 0.0225 66.7 1 0 1.02 0.96 1.07 PRS_PLINK_0.000251188643150958 856 Vascular complications of surgery and medical procedures Both 0 2 18 injuries & poisonings gray50 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 857 Mechanical complication of unspecified genitourinary device, implant, and graft Both 4 20 18 injuries & poisonings gray50 20, 4 4, 1 5, 2 5, 0 5, 1 -0.165 0.686 0.81 0.092 0.848 0.209 6.01 1 2.27 0.658 0.182 2.73 0.12 6930 0.166 2.45 0.946 0.024 1.18 0.34 1.27 -0.943 3.21 0.769 0.114 0.389 0.326 0.504 PRS_PLINK_0.000251188643150958 858 Complication of internal orthopedic device Both 2 23 18 injuries & poisonings gray50 23, 2 6, 0 6, 0 5, 1 6, 1 0.131 0.609 0.829 0.081 1.14 0.317 5.06 -0.0576 2.27 0.98 0.009 0.944 0.00221 34.8 0.93 2.66 0.726 0.139 2.54 0.00787 259 PRS_PLINK_0.000251188643150958 859 Complication due to other implant and internal device Both 1 21 18 injuries & poisonings gray50 21, 1 6, 1 5, 0 5, 0 5, 0 -0.772 1.08 0.476 0.322 0.462 0.00551 3.41 -1.9 13.8 0.891 0.05 0.15 2.4e-08 1380000 1.15 4.86 0.812 0.09 3.17 0.00065 179000 1.31 14 0.925 0.034 3.71 3.33 4.1 PRS_PLINK_0.000251188643150958 860 Bone marrow or stem cell transplant Both 0 3 2 neoplasms darkcyan 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 870 Open wounds of head; neck; and trunk Both 5 48 18 injuries & poisonings gray50 48, 5 11, 0 12, 2 12, 1 12, 2 0.426 0.418 0.308 0.511 1.53 0.707 3.79 1.6 1.76 0.364 0.439 4.95 0.141 1110 0.802 1.47 0.585 0.233 2.23 0.0371 361 1.9 1.8 0.291 0.536 6.68 0.125 3430 PRS_PLINK_0.000251188643150958 870.1 Open wound or laceration of eye or eyelid Both 0 2 18 injuries & poisonings gray50 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 870.2 Open wound of ear Both 0 3 18 injuries & poisonings gray50 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 870.3 Other open wound of head and face Both 1 13 18 injuries & poisonings gray50 13, 1 4, 0 3, 0 3, 1 3, 0 0.613 2.48 0.805 0.094 1.85 0.00116 277000 0.0553 648 1 0 1.06 0.698 1.78 PRS_PLINK_0.000251188643150958 870.4 Open wound of nose and sinus Both 1 2 18 injuries & poisonings gray50 2, 1 1, 1 1, 0 1, 1 1, 0 1.53 12700 1 0 4.62 1.44e-17 1.87e+23 -0.00462 39.4 1 0 0.995 0.886 1.03 PRS_PLINK_0.000251188643150958 870.5 Open wound of lip and mouth Both 0 7 18 injuries & poisonings gray50 7, 0 2 2 1 2 PRS_PLINK_0.000251188643150958 870.6 Open wound of neck Both 0 1 18 injuries & poisonings gray50 1, 0 PRS_PLINK_0.000251188643150958 870.8 Open wound of genital organs Both 1 1 18 injuries & poisonings gray50 1, 1 -0.00285 215 1 0 0.997 0.973 1.02 PRS_PLINK_0.000251188643150958 871 Open wounds of extremities Both 7 49 18 injuries & poisonings gray50 49, 7 12, 0 12, 3 12, 0 12, 4 0.0792 0.538 0.883 0.054 1.08 0.331 4.23 1.02 1.49 0.494 0.306 2.77 0.1 256 0.961 1.39 0.491 0.309 2.62 0.11 259 PRS_PLINK_0.000251188643150958 871.1 Open wound of hand except finger(s) Both 1 13 18 injuries & poisonings gray50 13, 1 4, 0 3, 1 3, 0 3, 0 0.17 1.05 0.871 0.06 1.19 0.186 16.3 0.649 7290000 1 0 1.91 0.204 46.9 PRS_PLINK_0.000251188643150958 871.2 Open wound of finger(s) Both 4 25 18 injuries & poisonings gray50 25, 4 7, 0 6, 2 6, 0 6, 2 -0.878 0.933 0.347 0.46 0.415 0.000663 2.71 0.6 2.11 0.776 0.11 1.82 0.0244 119 0.235 2.37 0.921 0.036 1.26 0.0126 46.6 PRS_PLINK_0.000251188643150958 871.3 Open wound of foot except toe(s) alone Both 1 12 18 injuries & poisonings gray50 12, 1 3, 0 3, 1 3, 0 3, 0 -0.0742 1.91 0.969 0.014 0.928 0.0323 2470 0.191 779000 1 0 1.21 0.64 1.74 PRS_PLINK_0.000251188643150958 871.4 Open wound of toe(s) Both 2 9 18 injuries & poisonings gray50 9, 2 3, 0 2, 0 2, 0 2, 2 -0.222 13.1 0.986 0.006 0.801 1.78e-05 37600 0.0581 2960 1 0 1.06 0.662 2.14 PRS_PLINK_0.000251188643150958 872 Traumatic amputation Both 1 15 18 injuries & poisonings gray50 15, 1 4, 0 4, 0 3, 0 4, 1 0.371 1.26 0.769 0.114 1.45 0.025 20.7 0.00311 917 1 0 1 0.797 1.54 PRS_PLINK_0.000251188643150958 874 Complication of amputation stump Both 0 3 18 injuries & poisonings gray50 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 875 Non-healing surgical wound Both 0 4 18 injuries & poisonings gray50 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 876 Posttraumatic wound infection not elsewhere classified Both 0 9 18 injuries & poisonings gray50 9, 0 3 2 2 2 PRS_PLINK_0.000251188643150958 907 Injuries to the nervous system Both 2 16 18 injuries & poisonings gray50 16, 2 4, 1 4, 1 4, 0 4, 0 -0.506 0.822 0.538 0.269 0.603 0.0556 2.84 3.72 5.98 0.534 0.273 41.4 0.0692 52.7 -0.918 12.7 0.942 0.026 0.399 0.383 0.414 0.562 119 0.996 0.002 1.75 0.000273 22300 PRS_PLINK_0.000251188643150958 910 Superficial injury, infected Both 0 3 18 injuries & poisonings gray50 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 911 Blister Both 5 8 18 injuries & poisonings gray50 8, 5 2, 0 2, 0 2, 2 2, 3 0.064 1.4 0.963 0.016 1.07 0.116 34.3 0.0263 4170 1 0 1.03 0.328 6.07 -0.487 13500 1 0 0.615 0.192 7.05 PRS_PLINK_0.000251188643150958 912 Insect bite Both 0 9 18 injuries & poisonings gray50 9, 0 3 2 2 2 PRS_PLINK_0.000251188643150958 913 Toxic effect of venom Both 2 6 18 injuries & poisonings gray50 6, 2 2, 0 1, 1 1, 0 2, 1 -0.391 1320 1 0 0.676 9.17e-07 1260000 0.186 2420 1 0 1.2 0.351 5.44 -9.08 4.37e+08 1 0 0.000114 6.11e-18 4.72e+08 PRS_PLINK_0.000251188643150958 916 Contusion Both 8 48 18 injuries & poisonings gray50 48, 8 11, 1 12, 1 12, 1 12, 5 0.385 0.412 0.349 0.457 1.47 0.614 3.54 0.425 1.56 0.785 0.105 1.53 0.0179 132 -0.221 1.43 0.877 0.057 0.801 0.0134 14.2 1.32 1.14 0.248 0.606 3.74 0.525 46.8 PRS_PLINK_0.000251188643150958 930 Allergic reaction to food Both 0 10 18 injuries & poisonings gray50 10, 0 2 2 2 3 PRS_PLINK_0.000251188643150958 931 Contact dermatitis and other eczema due to plants [except food] Both 1 11 13 dermatologic firebrick 11, 1 3, 0 3, 1 2, 0 3, 0 1.55 4.86 0.749 0.125 4.73 0.00179 38300 -0.0259 252 1 0 0.974 0.833 1.32 PRS_PLINK_0.000251188643150958 938 Dermatitis due to solar radiation Both 8 32 13 dermatologic firebrick 32, 8 7, 2 8, 1 8, 2 8, 3 -0.054 0.598 0.928 0.032 0.947 0.316 3.24 0.251 3.03 0.934 0.03 1.29 0.00249 228 -0.453 1.3 0.727 0.138 0.636 0.029 4.98 -1.23 2.57 0.634 0.198 0.293 0.00078 16.2 PRS_PLINK_0.000251188643150958 938.1 Acute dermatitis due to solar radiation Both 0 4 13 dermatologic firebrick 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 938.2 Chronic dermatitis due to solar radiation Both 8 31 13 dermatologic firebrick 31, 8 7, 2 8, 1 7, 2 8, 3 -0.0569 0.602 0.925 0.034 0.945 0.314 3.2 0.186 3.68 0.96 0.018 1.2 0.00372 9050 -0.626 1.45 0.667 0.176 0.535 0.0119 5.03 -1.23 2.57 0.634 0.198 0.293 0.00078 16.2 PRS_PLINK_0.000251188643150958 939 Atopic/contact dermatitis due to other or unspecified Both 12 40 13 dermatologic firebrick 40, 12 9, 3 10, 4 10, 1 10, 4 -0.27 0.472 0.567 0.246 0.763 0.313 1.86 -0.06 1.23 0.961 0.017 0.942 0.0856 8.77 -0.792 1.36 0.56 0.252 0.453 0.00728 5.76 0.343 1.31 0.794 0.1 1.41 0.0389 14.6 PRS_PLINK_0.000251188643150958 939.1 Contact and allergic dermatitis of eyelid Both 0 1 13 dermatologic firebrick 1, 0 PRS_PLINK_0.000251188643150958 941 Adverse reaction to serum or vaccine Both 0 5 18 injuries & poisonings gray50 5, 0 2 1 1 1 PRS_PLINK_0.000251188643150958 942 Infusion and transfusion reaction Both 0 4 18 injuries & poisonings gray50 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 946 Anaphylactic shock NOS Both 3 5 18 injuries & poisonings gray50 5, 3 1, 2 1, 0 1, 1 1, 0 -0.455 9870000 1 0 0.634 0.0808 5.71 0.0186 51.1 1 0 1.02 0.947 1.08 -0.724 1190 1 0 0.485 0.448 1.79 0.0161 15.7 0.999 0 1.02 0.953 1.3 PRS_PLINK_0.000251188643150958 947 Urticaria Both 5 15 13 dermatologic firebrick 15, 5 3, 0 4, 0 3, 3 4, 2 3.04 2.35 0.196 0.708 21 0.418 1600000 -0.209 2240 1 0 0.812 0.0483 3.77 -0.201 427 1 0 0.818 0.798 1.44 PRS_PLINK_0.000251188643150958 949 Allergies, other Both 13 40 18 injuries & poisonings gray50 40, 13 9, 2 10, 3 10, 3 10, 5 0.392 0.414 0.344 0.464 1.48 0.644 3.41 -0.566 1.27 0.656 0.183 0.568 0.0302 5.6 0.0288 1.3 0.982 0.008 1.03 0.0694 12 -0.00794 1.57 0.996 0.002 0.992 0.00925 20.2 PRS_PLINK_0.000251188643150958 952 Spinal cord injury without evidence of spinal bone injury Both 1 8 18 injuries & poisonings gray50 8, 1 2, 0 2, 1 2, 0 2, 0 0.587 204 0.998 0.001 1.8 0.624 7.36 0.638 7710 1 0 1.89 0.214 28.2 PRS_PLINK_0.000251188643150958 957 Injury to other and unspecified nerves Both 1 1 18 injuries & poisonings gray50 1, 1 0.000442 549 1 0 1 0.994 1.01 PRS_PLINK_0.000251188643150958 958 Certain early complications of trauma or procedure Both 0 10 18 injuries & poisonings gray50 10, 0 3 2 2 3 PRS_PLINK_0.000251188643150958 958.1 Postoperative shock Both 0 2 18 injuries & poisonings gray50 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 960 Poisoning by antibiotics Both 5 26 18 injuries & poisonings gray50 26, 5 6, 1 6, 3 6, 0 7, 1 0.351 0.483 0.467 0.331 1.42 0.653 3.91 1.47 1.69 0.384 0.416 4.34 0.302 643 0.306 1.83 0.867 0.062 1.36 0.0724 80.6 -1.05 2.56 0.681 0.167 0.349 6.82e-06 17.4 PRS_PLINK_0.000251188643150958 960.1 Adverse effects of antibacterials (not penicillins) Both 0 3 18 injuries & poisonings gray50 3, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 960.2 Allergy/adverse effect of penicillin Both 3 19 18 injuries & poisonings gray50 19, 3 4, 0 5, 3 4, 0 5, 0 0.101 0.993 0.919 0.037 1.11 0.0151 85.6 0.589 2.05 0.773 0.112 1.8 0.0069 101 PRS_PLINK_0.000251188643150958 961 Poisoning by other anti-infectives Both 0 9 18 injuries & poisonings gray50 9, 0 3 2 2 2 PRS_PLINK_0.000251188643150958 961.1 Poisoning/allergy of sulfonamides Both 2 6 18 injuries & poisonings gray50 6, 2 2, 0 1, 2 1, 0 2, 0 -0.475 73.3 0.995 0.002 0.622 0.000169 4440 0.0314 2450 1 0 1.03 0.351 3.19 PRS_PLINK_0.000251188643150958 962 Poisoning by hormones and synthetic substitutes Both 3 16 18 injuries & poisonings gray50 16, 3 4, 0 4, 0 4, 2 4, 1 0.448 1.03 0.663 0.179 1.56 0.163 38.4 0.259 2460 1 0 1.3 0.803 4.01 0.193 967 1 0 1.21 0.636 6.37 PRS_PLINK_0.000251188643150958 962.1 Adrenal cortical steroids causing adverse effects in therapeutic use Both 1 8 18 injuries & poisonings gray50 8, 1 2, 0 2, 0 2, 1 2, 0 0.0423 10400000 1 0 1.04 0.289 3.25 0.0216 1280 1 0 1.02 3.16e-10 77800 PRS_PLINK_0.000251188643150958 962.2 Insulins and antidiabetic agents causing adverse effects in therapeutic use Both 1 1 18 injuries & poisonings gray50 1, 1 -0.00295 379 1 0 0.997 0.981 1.01 PRS_PLINK_0.000251188643150958 962.3 Hormones and synthetic substitutes causing adverse effects in therapeutic use Both 2 9 18 injuries & poisonings gray50 9, 2 3, 0 2, 0 2, 0 2, 2 0.346 1.81 0.849 0.071 1.41 0.0574 28.6 -0.454 5790000 1 0 0.635 0.134 2.32 PRS_PLINK_0.000251188643150958 963 Poisoning by primarily systemic agents Both 0 25 18 injuries & poisonings gray50 25, 0 7 6 6 6 PRS_PLINK_0.000251188643150958 963.1 Antineoplastic and immunosuppressive drugs causing adverse effects Both 0 23 18 injuries & poisonings gray50 23, 0 6 6 5 6 PRS_PLINK_0.000251188643150958 964 Poisoning by agents primarily affecting blood constituents Both 0 13 18 injuries & poisonings gray50 13, 0 4 3 3 3 PRS_PLINK_0.000251188643150958 964.1 Anticoagulants causing adverse effects Both 0 12 18 injuries & poisonings gray50 12, 0 3 3 3 3 PRS_PLINK_0.000251188643150958 965 Poisoning by analgesics, antipyretics, and antirheumatics Both 1 5 18 injuries & poisonings gray50 5, 1 2, 0 1, 0 1, 1 1, 0 0.34 4e+06 1 0 1.41 0.234 13.6 -0.305 21600 1 0 0.737 0.311 3.29 PRS_PLINK_0.000251188643150958 965.1 Opiates and related narcotics causing adverse effects in therapeutic use Both 1 16 18 injuries & poisonings gray50 16, 1 3, 1 4, 0 4, 0 4, 0 -0.0615 0.864 0.943 0.025 0.94 0.215 4.56 0.00136 223 1 0 1 0.862 1.13 -0.325 440 0.999 0 0.722 0.0793 7.11 0.0127 239 1 0 1.01 1.13 2.48 PRS_PLINK_0.000251188643150958 965.3 Salicylates causing adverse effects in therapeutic use Both 0 1 18 injuries & poisonings gray50 1, 0 PRS_PLINK_0.000251188643150958 966 Poisoning by anticonvulsants and anti-Parkinsonism drugs Both 0 2 18 injuries & poisonings gray50 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 967 Adverse effects of sedatives or other central nervous system depressants and anesthetics Both 0 12 18 injuries & poisonings gray50 12, 0 3 3 3 3 PRS_PLINK_0.000251188643150958 969 Poisoning by psychotropic agents Both 0 1 18 injuries & poisonings gray50 1, 0 PRS_PLINK_0.000251188643150958 972 Poisoning by agents primarily affecting the cardiovascular system Both 0 4 18 injuries & poisonings gray50 4, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 972.6 Antihypertensive agents causing adverse effects Both 0 1 18 injuries & poisonings gray50 1, 0 PRS_PLINK_0.000251188643150958 974 Poisoning by water, mineral, and uric acid metabolism drugs Both 0 1 18 injuries & poisonings gray50 1, 0 PRS_PLINK_0.000251188643150958 975 Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system Both 0 1 18 injuries & poisonings gray50 1, 0 PRS_PLINK_0.000251188643150958 976 Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs Both 1 0 18 injuries & poisonings gray50 0, 1 PRS_PLINK_0.000251188643150958 977 Personal history of allergy to medicinal agents Both 0 21 18 injuries & poisonings gray50 21, 0 6 5 5 5 PRS_PLINK_0.000251188643150958 979 Adverse drug events and drug allergies Both 5 38 18 injuries & poisonings gray50 38, 5 9, 1 9, 3 9, 0 10, 1 -0.0808 0.495 0.87 0.06 0.922 0.342 2.8 0.734 1.39 0.598 0.223 2.08 0.102 45.2 -0.3 1.57 0.849 0.071 0.741 0.00292 57.3 1.26 1.94 0.515 0.288 3.53 0.133 1290 PRS_PLINK_0.000251188643150958 980 Encounter for long-term (current) use of antibiotics Both 3 13 1 infectious diseases blue 13, 3 4, 3 3, 0 3, 0 3, 0 -1.18 1.29 0.36 0.444 0.307 0.00875 2.17 0.00136 3.36 1 0 1 0.00632 216 1.34 15.3 0.93 0.031 3.8 3.4 4.2 -5.54 31.6 0.861 0.065 0.00393 0.00325 0.00474 PRS_PLINK_0.000251188643150958 985 Toxic effect of other metals Both 1 0 18 injuries & poisonings gray50 0, 1 PRS_PLINK_0.000251188643150958 989 Toxic effect of other substances, chiefly nonmedicinal as to source Both 1 2 18 injuries & poisonings gray50 2, 1 1, 0 1, 1 1, 0 1, 1 0.0363 156 1 0 1.04 0.877 1.27 -0.0255 66.1 1 0 0.975 0.912 1.05 PRS_PLINK_0.000251188643150958 990 Effects radiation NOS Both 0 21 18 injuries & poisonings gray50 21, 0 6 5 5 5 PRS_PLINK_0.000251188643150958 994 Sepsis and SIRS Both 1 27 18 injuries & poisonings gray50 27, 1 7, 0 7, 1 6, 0 7, 0 -0.128 0.736 0.862 0.064 0.88 0.0249 4.17 1.14 1.96 0.559 0.253 3.14 0.0536 3420 PRS_PLINK_0.000251188643150958 994.1 Systemic inflammatory response syndrome (SIRS) Both 0 2 18 injuries & poisonings gray50 2, 0 1 1 1 1 PRS_PLINK_0.000251188643150958 994.2 Sepsis Both 1 27 18 injuries & poisonings gray50 27, 1 7, 0 7, 1 6, 0 7, 0 -0.146 0.719 0.839 0.076 0.864 0.0248 3.86 1.14 1.96 0.559 0.253 3.14 0.0536 3420 PRS_PLINK_0.000251188643150958 994.21 Septic shock Both 0 6 18 injuries & poisonings gray50 6, 0 2 1 1 2 PRS_PLINK_0.000251188643150958