prs_id analysis_type phecode phecode_description category sex or_value ci_lower ci_upper p_value cases controls significant prs_log10p beta_value se_beta q1_vs_q2_beta_value q1_vs_q2_se_beta q1_vs_q2_p_value q1_vs_q2_log10p q1_vs_q2_or_value q1_vs_q2_ci_lower q1_vs_q2_ci_upper q1_vs_q3_beta_value q1_vs_q3_se_beta q1_vs_q3_p_value q1_vs_q3_log10p q1_vs_q3_or_value q1_vs_q3_ci_lower q1_vs_q3_ci_upper q1_vs_q4_beta_value q1_vs_q4_se_beta q1_vs_q4_p_value q1_vs_q4_log10p q1_vs_q4_or_value q1_vs_q4_ci_lower q1_vs_q4_ci_upper ukb-melanoma-gwas-catalog all 008 Intestinal infection Infectious Diseases Both 0.995 0.973 1.02 0.623 8932 89317 FALSE 0.20551195334083 -0.00547 0.0111 -0.015 0.0314 0.633 0.985 0.926 1.05 0.0191 0.0312 0.54 1.02 0.959 1.08 -0.0282 0.0317 0.374 0.972 0.914 1.03 ukb-melanoma-gwas-catalog all 008.5 Bacterial enteritis Infectious Diseases Both 0.981 0.943 1.02 0.332 2723 27227 FALSE 0.478861916295964 -0.0196 0.0202 -0.0275 0.0566 0.628 0.973 0.871 1.09 -0.0483 0.0569 0.395 0.953 0.852 1.07 -0.0327 0.0569 0.565 0.968 0.866 1.08 ukb-melanoma-gwas-catalog all 008.6 Viral Enteritis Infectious Diseases Both 0.988 0.921 1.06 0.731 863 8630 FALSE 0.13608262304214 -0.0123 0.0358 -0.0848 0.101 0.4 0.919 0.753 1.12 -0.0237 0.0994 0.811 0.977 0.803 1.19 -0.0659 0.101 0.513 0.936 0.768 1.14 ukb-melanoma-gwas-catalog all 008.7 Intestinal infection due to protozoa Infectious Diseases Both 1.21 0.907 1.62 0.195 53 530 FALSE 0.709965388637482 0.188 0.145 0.173 0.408 0.671 1.19 0.521 2.75 -0.0531 0.425 0.901 0.948 0.397 2.26 0.429 0.39 0.271 1.54 0.712 3.44 ukb-melanoma-gwas-catalog all 008.52 Intestinal infection due to C. difficile Infectious Diseases Both 1.06 0.98 1.15 0.142 656 6560 FALSE 0.847711655616944 0.06 0.0409 -0.029 0.116 0.802 0.971 0.773 1.22 -0.0619 0.116 0.595 0.94 0.747 1.18 0.0354 0.114 0.756 1.04 0.828 1.3 ukb-melanoma-gwas-catalog all 010 Tuberculosis Infectious Diseases Both 0.905 0.772 1.06 0.213 174 1740 FALSE 0.671620396561262 -0.0998 0.0801 -0.298 0.228 0.191 0.743 0.471 1.16 -0.0267 0.215 0.901 0.974 0.635 1.49 -0.107 0.221 0.629 0.899 0.579 1.39 ukb-melanoma-gwas-catalog all 038 Septicemia Infectious Diseases Both 1 0.968 1.03 0.98 4198 41980 FALSE 0.00877392430750515 -0.00041 0.0162 0.00635 0.0458 0.89 1.01 0.92 1.1 0.0388 0.0456 0.395 1.04 0.951 1.14 -0.0336 0.0464 0.469 0.967 0.883 1.06 ukb-melanoma-gwas-catalog all 038.1 Gram negative septicemia Infectious Diseases Both 0.988 0.92 1.06 0.734 853 8530 FALSE 0.134303940083929 -0.0123 0.036 -0.0781 0.103 0.447 0.925 0.756 1.13 0.0462 0.0999 0.644 1.05 0.861 1.27 -0.0409 0.102 0.688 0.96 0.786 1.17 ukb-melanoma-gwas-catalog all 038.2 Gram positive septicemia Infectious Diseases Both 0.983 0.896 1.08 0.712 497 4970 FALSE 0.147520006363144 -0.0174 0.0472 0.0339 0.135 0.802 1.03 0.793 1.35 0.166 0.131 0.206 1.18 0.912 1.53 -0.0124 0.137 0.928 0.988 0.755 1.29 ukb-melanoma-gwas-catalog all 041 Bacterial infection NOS Infectious Diseases Both 1 0.984 1.02 0.743 12100 120995 FALSE 0.129011186239425 0.00313 0.00957 -0.0102 0.0271 0.706 0.99 0.939 1.04 0.0216 0.027 0.423 1.02 0.969 1.08 0.00665 0.0271 0.806 1.01 0.955 1.06 ukb-melanoma-gwas-catalog all 041.1 Staphylococcus infections Infectious Diseases Both 1.02 0.982 1.06 0.324 3131 31305 FALSE 0.489454989793388 0.0185 0.0188 -0.0475 0.0539 0.378 0.954 0.858 1.06 0.0748 0.0525 0.155 1.08 0.972 1.19 0.0224 0.0533 0.674 1.02 0.921 1.14 ukb-melanoma-gwas-catalog all 041.2 Streptococcus infection Infectious Diseases Both 1 0.952 1.05 0.953 1639 16390 FALSE 0.0209070993616736 0.00153 0.026 -0.123 0.0747 0.0987 0.884 0.763 1.02 0.0686 0.0715 0.337 1.07 0.931 1.23 -0.0549 0.0734 0.455 0.947 0.819 1.09 ukb-melanoma-gwas-catalog all 041.4 E. coli Infectious Diseases Both 0.994 0.955 1.03 0.748 2724 27240 FALSE 0.126098402135539 -0.00648 0.0202 -0.0467 0.0566 0.409 0.954 0.854 1.07 -0.045 0.0565 0.426 0.956 0.856 1.07 -0.065 0.057 0.254 0.937 0.838 1.05 ukb-melanoma-gwas-catalog all 053 Herpes zoster Infectious Diseases Both 0.967 0.875 1.07 0.516 421 4210 FALSE 0.287350298372789 -0.0332 0.0511 -0.25 0.144 0.0815 0.779 0.586 1.03 -0.304 0.146 0.0372 0.738 0.553 0.982 -0.0364 0.136 0.79 0.964 0.737 1.26 ukb-melanoma-gwas-catalog all 053.1 Herpes zoster with nervous system complications Infectious Diseases Both 1.17 0.947 1.44 0.143 96 960 FALSE 0.844663962534938 0.155 0.106 0.25 0.296 0.399 1.28 0.714 2.34 -0.134 0.32 0.676 0.875 0.458 1.66 0.346 0.295 0.241 1.41 0.79 2.57 ukb-melanoma-gwas-catalog all 054 Herpes simplex Infectious Diseases Both 1.11 0.962 1.27 0.155 214 2140 FALSE 0.809668301829709 0.102 0.0714 0.448 0.204 0.0282 1.57 1.05 2.36 0.0132 0.222 0.952 1.01 0.652 1.58 0.398 0.207 0.0546 1.49 0.992 2.26 ukb-melanoma-gwas-catalog all 070 Viral hepatitis Infectious Diseases Both 1.04 0.954 1.13 0.386 593 5930 FALSE 0.413412695328245 0.0373 0.0431 0.0681 0.124 0.584 1.07 0.839 1.37 0.0926 0.124 0.455 1.1 0.86 1.4 0.162 0.122 0.185 1.18 0.925 1.5 ukb-melanoma-gwas-catalog all 070.1 Viral hepatitis A Infectious Diseases Both 0.978 0.762 1.25 0.858 69 690 FALSE 0.0665127121512946 -0.0223 0.124 -0.381 0.367 0.299 0.683 0.321 1.42 0.0716 0.332 0.829 1.07 0.553 2.1 0.0312 0.34 0.927 1.03 0.522 2.04 ukb-melanoma-gwas-catalog all 070.2 Viral hepatitis B Infectious Diseases Both 1.02 0.852 1.22 0.838 134 1340 FALSE 0.0767559813697235 0.0183 0.0898 -0.0254 0.248 0.918 0.975 0.595 1.6 -0.43 0.275 0.118 0.651 0.373 1.12 0.153 0.238 0.522 1.16 0.728 1.87 ukb-melanoma-gwas-catalog all 070.3 Viral hepatitis C Infectious Diseases Both 1.06 0.928 1.2 0.404 257 2570 FALSE 0.393618634889395 0.0544 0.0652 0.298 0.191 0.119 1.35 0.926 1.97 0.378 0.189 0.0455 1.46 1.01 2.13 0.17 0.196 0.387 1.18 0.805 1.75 ukb-melanoma-gwas-catalog all 071 Human immunodeficiency virus [HIV] disease Infectious Diseases Both 1.05 0.884 1.24 0.582 147 1470 FALSE 0.235077015350112 0.0475 0.0862 -0.00233 0.248 0.992 0.998 0.609 1.63 0.213 0.236 0.367 1.24 0.777 1.98 0.0491 0.249 0.844 1.05 0.64 1.72 ukb-melanoma-gwas-catalog all 071.1 HIV infection, symptomatic Infectious Diseases Both 1.11 0.918 1.35 0.273 117 1170 FALSE 0.563837352959244 0.106 0.0966 0.061 0.278 0.826 1.06 0.611 1.85 0.171 0.272 0.529 1.19 0.693 2.04 0.157 0.278 0.571 1.17 0.675 2.04 ukb-melanoma-gwas-catalog all 078 Viral warts & HPV Infectious Diseases Both 1.03 0.963 1.1 0.409 1006 10060 FALSE 0.388276691992658 0.0274 0.0331 -0.0424 0.0946 0.654 0.959 0.796 1.15 0.059 0.0925 0.524 1.06 0.885 1.27 0.0165 0.0941 0.861 1.02 0.845 1.22 ukb-melanoma-gwas-catalog all 079 Viral infection Infectious Diseases Both 0.992 0.954 1.03 0.673 2805 28050 FALSE 0.171984935776023 -0.00839 0.0199 0.0543 0.0551 0.325 1.06 0.948 1.18 -0.088 0.057 0.122 0.916 0.819 1.02 -0.0096 0.0562 0.864 0.99 0.887 1.11 ukb-melanoma-gwas-catalog all 079.1 Varicella infection Infectious Diseases Both 1.17 0.909 1.51 0.215 65 650 FALSE 0.667561540084395 0.158 0.128 0.283 0.381 0.457 1.33 0.62 2.91 0.284 0.378 0.452 1.33 0.624 2.9 0.525 0.37 0.155 1.69 0.818 3.63 ukb-melanoma-gwas-catalog all 079.2 Infectious mononucleosis Infectious Diseases Both 1.05 0.816 1.34 0.717 69 690 FALSE 0.1444808443322 0.0451 0.124 0.292 0.357 0.414 1.34 0.658 2.78 0.349 0.357 0.329 1.42 0.697 2.94 0.14 0.366 0.701 1.15 0.552 2.43 ukb-melanoma-gwas-catalog all 080 Postoperative infection Infectious Diseases Both 1.01 0.981 1.04 0.469 4489 44888 FALSE 0.328827157284917 0.0114 0.0157 -0.00534 0.0448 0.905 0.995 0.911 1.09 0.0463 0.0443 0.296 1.05 0.96 1.14 0.0276 0.0446 0.536 1.03 0.942 1.12 ukb-melanoma-gwas-catalog all 081 Infection/inflammation of internal prosthetic device; implant; and graft Infectious Diseases Both 1 0.961 1.04 0.945 2487 24870 FALSE 0.0245681914907371 0.00144 0.0211 -0.0755 0.0598 0.207 0.927 0.825 1.04 -0.0362 0.0593 0.542 0.964 0.859 1.08 0.00146 0.059 0.98 1 0.892 1.12 ukb-melanoma-gwas-catalog all 090 Sexually transmitted infections (not HIV or hepatitis) Infectious Diseases Both 0.992 0.779 1.26 0.949 73 730 FALSE 0.0227337875727074 -0.0077 0.121 -0.0842 0.34 0.804 0.919 0.463 1.82 -0.0452 0.336 0.893 0.956 0.486 1.87 -0.112 0.342 0.744 0.894 0.449 1.77 ukb-melanoma-gwas-catalog all 110 Dermatophytosis / Dermatomycosis Infectious Diseases Both 1.01 0.896 1.14 0.84 286 2860 FALSE 0.0757207139381184 0.0125 0.0619 0.119 0.172 0.491 1.13 0.802 1.58 0.0987 0.173 0.569 1.1 0.784 1.56 -0.105 0.181 0.56 0.9 0.629 1.29 ukb-melanoma-gwas-catalog all 110.1 Dermatophytosis Infectious Diseases Both 1.01 0.894 1.14 0.86 280 2800 FALSE 0.0655015487564323 0.011 0.0625 0.11 0.174 0.529 1.12 0.792 1.58 0.0875 0.175 0.617 1.09 0.773 1.54 -0.104 0.182 0.568 0.901 0.628 1.29 ukb-melanoma-gwas-catalog all 110.11 Dermatophytosis of nail Infectious Diseases Both 1.16 0.921 1.47 0.196 76 760 FALSE 0.707743928643524 0.152 0.117 0.316 0.333 0.343 1.37 0.709 2.7 -0.0575 0.358 0.872 0.944 0.456 1.95 0.345 0.333 0.301 1.41 0.731 2.79 ukb-melanoma-gwas-catalog all 110.12 Althete's foot Infectious Diseases Both 0.885 0.745 1.05 0.164 141 1410 FALSE 0.785156151952302 -0.122 0.0875 -0.084 0.231 0.716 0.919 0.582 1.45 -0.259 0.239 0.28 0.772 0.478 1.24 -0.638 0.265 0.0159 0.529 0.309 0.886 ukb-melanoma-gwas-catalog all 112 Candidiasis Infectious Diseases Both 1.01 0.969 1.06 0.559 2134 21340 FALSE 0.252588192113577 0.0133 0.0228 0.0407 0.0635 0.521 1.04 0.92 1.18 -0.0875 0.0654 0.181 0.916 0.806 1.04 0.00109 0.0641 0.986 1 0.883 1.14 ukb-melanoma-gwas-catalog all 117 Mycoses Infectious Diseases Both 1.02 0.9 1.15 0.766 275 2750 FALSE 0.115771230367396 0.0188 0.063 0.0757 0.178 0.671 1.08 0.759 1.53 -0.0513 0.183 0.779 0.95 0.662 1.36 0.121 0.176 0.494 1.13 0.797 1.6 ukb-melanoma-gwas-catalog all 117.4 Aspergillosis Infectious Diseases Both 0.94 0.799 1.1 0.45 165 1650 FALSE 0.346787486224656 -0.0617 0.0817 -0.225 0.221 0.309 0.799 0.514 1.23 -0.441 0.234 0.0592 0.644 0.402 1.02 -0.162 0.218 0.456 0.85 0.552 1.31 ukb-melanoma-gwas-catalog all 130 Spirochetal infection Infectious Diseases Both 1.09 0.867 1.37 0.45 80 800 FALSE 0.346787486224656 0.0868 0.115 0.262 0.337 0.437 1.3 0.664 2.58 0.283 0.338 0.403 1.33 0.676 2.65 0.287 0.337 0.394 1.33 0.683 2.65 ukb-melanoma-gwas-catalog all 133 Arthropod-borne diseases Infectious Diseases Both 0.933 0.73 1.19 0.574 70 700 FALSE 0.241088107602026 -0.0691 0.123 -0.133 0.345 0.7 0.876 0.435 1.74 0.0218 0.333 0.948 1.02 0.524 1.99 -0.14 0.343 0.684 0.869 0.433 1.73 ukb-melanoma-gwas-catalog all 134 Helminthiases Infectious Diseases Both 0.959 0.799 1.15 0.65 129 1290 FALSE 0.187086643357144 -0.0417 0.0921 -0.134 0.255 0.6 0.875 0.525 1.45 -0.385 0.272 0.157 0.68 0.392 1.16 0.117 0.244 0.633 1.12 0.693 1.83 ukb-melanoma-gwas-catalog all 134.1 Intestinal helminthiases Infectious Diseases Both 0.996 0.816 1.22 0.968 107 1070 FALSE 0.0141246426916063 -0.00404 0.101 -0.0686 0.281 0.807 0.934 0.532 1.64 -0.324 0.301 0.281 0.723 0.392 1.31 0.239 0.268 0.372 1.27 0.749 2.17 ukb-melanoma-gwas-catalog all 136 Other infectious and parasitic diseases Infectious Diseases Both 1.04 0.905 1.2 0.552 207 2070 FALSE 0.258060922270801 0.0431 0.0724 -0.231 0.211 0.274 0.794 0.521 1.2 -0.0785 0.203 0.699 0.924 0.618 1.38 0.0662 0.198 0.738 1.07 0.723 1.58 ukb-melanoma-gwas-catalog all 145 Cancer of mouth Neoplasms Both 1.05 0.971 1.14 0.207 648 6480 FALSE 0.684029654543082 0.0522 0.0413 -0.0424 0.12 0.724 0.958 0.757 1.21 0.0465 0.118 0.694 1.05 0.831 1.32 0.164 0.115 0.155 1.18 0.94 1.48 ukb-melanoma-gwas-catalog all 145.2 Cancer of tongue Neoplasms Both 0.999 0.888 1.12 0.99 310 3100 FALSE 0.00436480540245009 -0.000725 0.0597 0.0533 0.169 0.753 1.05 0.755 1.47 0.194 0.165 0.24 1.21 0.878 1.68 -0.0447 0.174 0.798 0.956 0.678 1.35 ukb-melanoma-gwas-catalog all 145.3 Cancer of major salivary glands Neoplasms Both 1.18 0.962 1.44 0.109 105 1050 FALSE 0.962573502059376 0.164 0.102 0.465 0.303 0.125 1.59 0.876 2.96 0.297 0.313 0.343 1.35 0.723 2.55 0.53 0.301 0.0784 1.7 0.942 3.15 ukb-melanoma-gwas-catalog all 145.5 Cancer of the mouth floor Neoplasms Both 1.28 0.966 1.71 0.0809 54 540 FALSE 1.09205147838773 0.25 0.143 -1.03 0.487 0.0344 0.357 0.12 0.922 -0.18 0.388 0.643 0.835 0.376 1.82 0.257 0.352 0.465 1.29 0.646 2.64 ukb-melanoma-gwas-catalog all 149 Cancer of larynx, pharynx, nasal cavities Neoplasms Both 1.02 0.939 1.1 0.655 643 6428 FALSE 0.183758700008217 0.0185 0.0413 -0.0188 0.119 0.874 0.981 0.777 1.24 0.0629 0.116 0.589 1.06 0.847 1.34 0.0678 0.117 0.562 1.07 0.85 1.35 ukb-melanoma-gwas-catalog all 149.1 Cancer of oropharynx Neoplasms Both 0.976 0.857 1.11 0.71 253 2528 FALSE 0.148741651280925 -0.0245 0.0658 -0.246 0.186 0.186 0.782 0.539 1.13 -0.112 0.18 0.533 0.894 0.626 1.27 -0.151 0.182 0.407 0.86 0.6 1.23 ukb-melanoma-gwas-catalog all 149.4 Cancer of larynx Neoplasms Both 1.05 0.926 1.19 0.436 265 2648 FALSE 0.360513510731414 0.0501 0.0643 0.241 0.186 0.197 1.27 0.882 1.84 0.212 0.188 0.26 1.24 0.854 1.8 0.264 0.187 0.157 1.3 0.903 1.89 ukb-melanoma-gwas-catalog all 149.9 Cancer of of nasal cavities Neoplasms Both 1.18 0.901 1.55 0.217 57 570 FALSE 0.66354026615147 0.167 0.135 -0.27 0.411 0.511 0.763 0.327 1.75 0.0985 0.389 0.8 1.1 0.504 2.44 0.431 0.377 0.253 1.54 0.73 3.33 ukb-melanoma-gwas-catalog all 150 Cancer of esophagus Neoplasms Both 0.972 0.901 1.05 0.449 764 7640 FALSE 0.347753658996677 -0.0289 0.0381 -0.0833 0.106 0.43 0.92 0.747 1.13 -0.119 0.107 0.263 0.888 0.719 1.09 -0.112 0.107 0.294 0.894 0.724 1.1 ukb-melanoma-gwas-catalog all 151 Cancer of stomach Neoplasms Both 0.973 0.892 1.06 0.536 570 5700 FALSE 0.27083521030723 -0.0273 0.0442 0.00213 0.123 0.986 1 0.787 1.28 -0.0777 0.125 0.535 0.925 0.723 1.18 -0.0129 0.124 0.917 0.987 0.773 1.26 ukb-melanoma-gwas-catalog all 153 Colorectal cancer Neoplasms Both 1 0.975 1.04 0.763 4610 46100 FALSE 0.11747546204512 0.00467 0.0155 -0.0558 0.0442 0.207 0.946 0.867 1.03 0.0506 0.0432 0.241 1.05 0.966 1.15 -0.0198 0.044 0.653 0.98 0.899 1.07 ukb-melanoma-gwas-catalog all 153.2 Colon cancer Neoplasms Both 1.02 0.982 1.06 0.327 3109 31090 FALSE 0.485452247339714 0.0185 0.0189 -0.0565 0.0542 0.298 0.945 0.85 1.05 0.0621 0.0529 0.24 1.06 0.959 1.18 0.0274 0.0533 0.607 1.03 0.926 1.14 ukb-melanoma-gwas-catalog all 153.3 Malignant neoplasm of rectum, rectosigmoid junction, and anus Neoplasms Both 0.991 0.948 1.04 0.7 2165 21650 FALSE 0.154901959985743 -0.00872 0.0226 -0.0521 0.064 0.416 0.949 0.837 1.08 0.0327 0.0629 0.603 1.03 0.913 1.17 -0.0641 0.0644 0.32 0.938 0.827 1.06 ukb-melanoma-gwas-catalog all 155 Cancer of liver and intrahepatic bile duct Neoplasms Both 1.01 0.908 1.12 0.895 402 4020 FALSE 0.048176964684088 0.00692 0.0524 -0.213 0.148 0.149 0.808 0.604 1.08 -0.101 0.144 0.484 0.904 0.68 1.2 -0.143 0.146 0.328 0.867 0.65 1.15 ukb-melanoma-gwas-catalog all 155.1 Malignant neoplasm of liver, primary Neoplasms Both 0.971 0.823 1.15 0.727 158 1580 FALSE 0.138465589140962 -0.0292 0.0837 -0.156 0.225 0.488 0.855 0.546 1.33 -0.326 0.236 0.169 0.722 0.449 1.15 -0.203 0.229 0.373 0.816 0.517 1.28 ukb-melanoma-gwas-catalog all 157 Pancreatic cancer Neoplasms Both 1.02 0.94 1.1 0.647 659 6590 FALSE 0.1890957193313 0.0188 0.041 -0.00144 0.117 0.99 0.999 0.793 1.26 0.0857 0.115 0.456 1.09 0.869 1.37 0.0382 0.117 0.744 1.04 0.826 1.31 ukb-melanoma-gwas-catalog all 158 Neoplasm of unspecified nature of digestive system Neoplasms Both 1.01 0.952 1.08 0.657 1064 10640 FALSE 0.182434630440219 0.0143 0.0322 -0.00163 0.0908 0.986 0.998 0.835 1.19 -0.0713 0.0926 0.441 0.931 0.776 1.12 0.0667 0.09 0.459 1.07 0.896 1.28 ukb-melanoma-gwas-catalog all 159 Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum Neoplasms Both 0.994 0.967 1.02 0.654 5582 55820 FALSE 0.184422251675733 -0.00631 0.0141 0.0785 0.0395 0.0472 1.08 1 1.17 0.00304 0.0402 0.94 1 0.927 1.09 0.019 0.0402 0.636 1.02 0.942 1.1 ukb-melanoma-gwas-catalog all 159.2 Malignant neoplasm of small intestine, including duodenum Neoplasms Both 0.885 0.761 1.03 0.111 189 1890 FALSE 0.954677021213343 -0.122 0.0765 0.174 0.207 0.401 1.19 0.792 1.79 -0.167 0.224 0.457 0.846 0.541 1.32 -0.0558 0.217 0.797 0.946 0.615 1.45 ukb-melanoma-gwas-catalog all 159.3 Malignant neoplasm of gallbladder and extrahepatic bile ducts Neoplasms Both 1.02 0.882 1.18 0.805 205 2050 FALSE 0.0942041196321315 0.018 0.073 0.169 0.202 0.401 1.18 0.796 1.77 -0.0708 0.212 0.738 0.932 0.611 1.42 -0.0175 0.208 0.933 0.983 0.651 1.48 ukb-melanoma-gwas-catalog all 159.4 Malignant neoplasm of retroperitoneum and peritoneum Neoplasms Both 0.973 0.839 1.13 0.715 192 1920 FALSE 0.145693958198919 -0.0275 0.0753 0.234 0.212 0.27 1.26 0.832 1.93 0.0628 0.218 0.773 1.06 0.692 1.64 0.0952 0.218 0.662 1.1 0.715 1.7 ukb-melanoma-gwas-catalog all 164 Cancer of intrathoracic organs Neoplasms Both 1.01 0.773 1.32 0.917 60 600 FALSE 0.0376306643299789 0.0139 0.134 -0.0369 0.351 0.916 0.964 0.476 1.95 -0.351 0.378 0.352 0.704 0.323 1.49 -0.382 0.38 0.315 0.682 0.313 1.45 ukb-melanoma-gwas-catalog all 165 Cancer within the respiratory system Neoplasms Both 0.998 0.96 1.04 0.932 2833 28319 FALSE 0.0305840876460186 -0.00168 0.0198 0.0553 0.0555 0.319 1.06 0.948 1.18 0.0193 0.056 0.73 1.02 0.913 1.14 -0.0117 0.0565 0.836 0.988 0.885 1.1 ukb-melanoma-gwas-catalog all 165.1 Cancer of bronchus; lung Neoplasms Both 0.997 0.954 1.04 0.887 2238 22380 FALSE 0.0520763801682736 -0.00317 0.0222 0.0863 0.0624 0.167 1.09 0.965 1.23 0.0317 0.0632 0.616 1.03 0.912 1.17 -0.0106 0.0639 0.868 0.989 0.873 1.12 ukb-melanoma-gwas-catalog all 170 Cancer of bone and connective tissue Neoplasms Both 1.1 0.996 1.21 0.0603 445 4447 FALSE 1.21968268785985 0.0935 0.0498 -0.0553 0.145 0.702 0.946 0.711 1.26 -0.00699 0.143 0.961 0.993 0.749 1.32 0.217 0.136 0.112 1.24 0.951 1.63 ukb-melanoma-gwas-catalog all 170.1 Bone cancer Neoplasms Both 0.978 0.817 1.17 0.808 131 1310 FALSE 0.0925886392254138 -0.0221 0.0909 -0.316 0.255 0.216 0.729 0.436 1.21 -0.279 0.253 0.27 0.757 0.455 1.24 -0.117 0.243 0.631 0.89 0.548 1.44 ukb-melanoma-gwas-catalog all 170.2 Cancer of connective tissue Neoplasms Both 1.14 1.02 1.27 0.0255 331 3307 TRUE 1.59345981956604 0.129 0.0577 0.0398 0.169 0.814 1.04 0.745 1.45 0.0704 0.169 0.676 1.07 0.769 1.5 0.339 0.16 0.0336 1.4 1.03 1.93 ukb-melanoma-gwas-catalog all 172 Skin cancer Neoplasms Both 1.24 1.22 1.26 3.32e-128 13624 136233 TRUE 127.478861916296 0.217 0.00899 0.214 0.0277 1.2e-14 1.24 1.17 1.31 0.316 0.0272 2.81e-31 1.37 1.3 1.45 0.545 0.0261 1.11e-96 1.73 1.64 1.82 ukb-melanoma-gwas-catalog all 172.1 Melanomas of skin, dx or hx Neoplasms Both 1.49 1.44 1.55 5.8e-88 2718 27180 TRUE 87.2365720064371 0.402 0.0202 0.324 0.0677 1.71e-06 1.38 1.21 1.58 0.567 0.0649 2.38e-18 1.76 1.55 2 0.967 0.0612 3.79e-56 2.63 2.33 2.97 ukb-melanoma-gwas-catalog all 172.2 Other non-epithelial cancer of skin Neoplasms Both 1.21 1.18 1.23 7.55e-78 11030 110298 TRUE 77.1220530483708 0.187 0.00999 0.185 0.0304 1.2e-09 1.2 1.13 1.28 0.274 0.0299 5.26e-20 1.31 1.24 1.39 0.467 0.0289 8.88e-59 1.59 1.51 1.69 ukb-melanoma-gwas-catalog all 172.3 Carcinoma in situ of skin Neoplasms Both 1.31 1.21 1.42 4.64e-11 667 6670 TRUE 10.3334820194451 0.268 0.0407 0.162 0.128 0.206 1.18 0.914 1.51 0.281 0.125 0.0248 1.32 1.04 1.7 0.715 0.117 8.61e-10 2.04 1.63 2.58 ukb-melanoma-gwas-catalog all 172.11 Melanomas of skin Neoplasms Both 1.49 1.44 1.55 5.8e-88 2718 27180 TRUE 87.2365720064371 0.402 0.0202 0.324 0.0677 1.71e-06 1.38 1.21 1.58 0.567 0.0649 2.38e-18 1.76 1.55 2 0.967 0.0612 3.79e-56 2.63 2.33 2.97 ukb-melanoma-gwas-catalog all 173 Neoplasm of uncertain behavior of skin Neoplasms Both 1.26 1.08 1.47 0.00273 182 1820 TRUE 2.56383735295924 0.231 0.0772 0.68 0.251 0.00674 1.97 1.21 3.29 0.609 0.251 0.0153 1.84 1.13 3.07 0.86 0.243 4e-04 2.36 1.48 3.88 ukb-melanoma-gwas-catalog all 174 Breast cancer Neoplasms Both 1.02 1 1.04 0.0407 12771 127136 TRUE 1.39040559077478 0.0191 0.00931 0.0327 0.0264 0.215 1.03 0.981 1.09 0.0185 0.0265 0.485 1.02 0.967 1.07 0.048 0.0264 0.0691 1.05 0.996 1.1 ukb-melanoma-gwas-catalog all 174.1 Breast cancer [female] Neoplasms Female 1.02 1 1.04 0.0395 12549 124973 TRUE 1.40340290437354 0.0193 0.00939 0.0315 0.0266 0.237 1.03 0.979 1.09 0.0142 0.0268 0.597 1.01 0.962 1.07 0.0498 0.0266 0.0613 1.05 0.998 1.11 ukb-melanoma-gwas-catalog all 174.3 Neoplasm of uncertain behavior of breast Neoplasms Both 0.862 0.709 1.05 0.132 115 1150 FALSE 0.87942606879415 -0.148 0.0981 -0.166 0.267 0.536 0.847 0.497 1.44 0.0677 0.253 0.789 1.07 0.649 1.77 -0.553 0.294 0.0601 0.575 0.315 1.02 ukb-melanoma-gwas-catalog all 174.11 Malignant neoplasm of female breast Neoplasms Female 1.02 1 1.04 0.0153 11767 117670 TRUE 1.8153085691824 0.0235 0.0097 0.0296 0.0276 0.283 1.03 0.976 1.09 0.0214 0.0276 0.44 1.02 0.968 1.08 0.0581 0.0275 0.0344 1.06 1 1.12 ukb-melanoma-gwas-catalog all 175 Acquired absence of breast Neoplasms Female 1.03 0.985 1.07 0.205 2406 24060 FALSE 0.688246138944246 0.0272 0.0214 0.103 0.0607 0.0907 1.11 0.984 1.25 0.0876 0.0609 0.15 1.09 0.969 1.23 0.024 0.0619 0.698 1.02 0.907 1.16 ukb-melanoma-gwas-catalog all 180 Cervical cancer and dysplasia Neoplasms Female 0.986 0.953 1.02 0.412 3640 36400 FALSE 0.385102783966865 -0.0143 0.0174 -0.0173 0.0489 0.723 0.983 0.893 1.08 -0.0447 0.0493 0.365 0.956 0.868 1.05 -0.0292 0.0492 0.552 0.971 0.882 1.07 ukb-melanoma-gwas-catalog all 180.1 Cervical cancer Neoplasms Female 0.987 0.938 1.04 0.613 1655 16550 FALSE 0.212539525481585 -0.0131 0.0258 0.0278 0.0729 0.703 1.03 0.891 1.19 0.0476 0.0726 0.513 1.05 0.909 1.21 -0.0139 0.0738 0.851 0.986 0.853 1.14 ukb-melanoma-gwas-catalog all 180.3 Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia] Neoplasms Female 0.987 0.943 1.03 0.572 2081 20810 FALSE 0.242603971206976 -0.0131 0.0231 -0.0548 0.0644 0.395 0.947 0.834 1.07 -0.124 0.0655 0.0575 0.883 0.776 1 -0.037 0.0642 0.565 0.964 0.85 1.09 ukb-melanoma-gwas-catalog all 182 Malignant neoplasm of uterus Neoplasms Female 1.02 0.96 1.08 0.562 1288 12880 FALSE 0.250263684430939 0.017 0.0293 -0.0226 0.0828 0.785 0.978 0.831 1.15 -0.035 0.0832 0.674 0.966 0.82 1.14 0.0206 0.0821 0.802 1.02 0.869 1.2 ukb-melanoma-gwas-catalog all 184 Cancer of other female genital organs Neoplasms Female 0.991 0.951 1.03 0.686 2467 24670 FALSE 0.163675884293248 -0.00857 0.0212 -0.0358 0.0597 0.548 0.965 0.858 1.08 -0.00342 0.0593 0.954 0.997 0.887 1.12 -0.0373 0.0599 0.534 0.963 0.857 1.08 ukb-melanoma-gwas-catalog all 184.1 Malignant neoplasm of ovary and other uterine adnexa Neoplasms Female 0.989 0.945 1.03 0.615 2131 21310 FALSE 0.211124884224583 -0.0114 0.0228 0.00665 0.0644 0.918 1.01 0.887 1.14 0.0475 0.0639 0.457 1.05 0.925 1.19 -0.0187 0.065 0.773 0.981 0.864 1.11 ukb-melanoma-gwas-catalog all 184.2 Cancer of other female genital organs (excluding uterus and ovary) Neoplasms Female 0.989 0.879 1.11 0.856 305 3050 FALSE 0.0675262353228468 -0.0109 0.0601 -0.118 0.168 0.481 0.888 0.638 1.24 -0.164 0.17 0.336 0.849 0.606 1.19 -0.0697 0.166 0.674 0.933 0.673 1.29 ukb-melanoma-gwas-catalog all 184.11 Malignant neoplasm of ovary Neoplasms Female 0.988 0.944 1.03 0.587 2108 21080 FALSE 0.231361898752386 -0.0124 0.0229 0.0162 0.0647 0.802 1.02 0.895 1.15 0.0497 0.0643 0.439 1.05 0.927 1.19 -0.0212 0.0654 0.746 0.979 0.861 1.11 ukb-melanoma-gwas-catalog all 185 Cancer of prostate Neoplasms Male 1.01 0.984 1.03 0.497 6719 64751 FALSE 0.303643611266668 0.00873 0.0129 -0.0322 0.0365 0.377 0.968 0.901 1.04 0.00914 0.0362 0.8 1.01 0.94 1.08 -0.0011 0.0364 0.976 0.999 0.93 1.07 ukb-melanoma-gwas-catalog all 187 Cancer of other male genital organs Neoplasms Male 1.01 0.976 1.05 0.504 3114 31140 FALSE 0.297569463554475 0.0126 0.0189 -0.0379 0.0535 0.478 0.963 0.867 1.07 -0.011 0.0533 0.837 0.989 0.891 1.1 0.0236 0.053 0.657 1.02 0.923 1.14 ukb-melanoma-gwas-catalog all 187.1 Malignant neoplasm of unspecified male genital organ Neoplasms Male 1.01 0.97 1.05 0.676 2835 28350 FALSE 0.170053304058364 0.00826 0.0198 -0.0697 0.0562 0.215 0.933 0.835 1.04 -0.0115 0.0555 0.836 0.989 0.887 1.1 0.0115 0.0554 0.835 1.01 0.907 1.13 ukb-melanoma-gwas-catalog all 187.2 Malignant neoplasm of testis Neoplasms Male 1.01 0.977 1.05 0.461 2973 29730 FALSE 0.336299074610352 0.0142 0.0193 -0.0443 0.0549 0.419 0.957 0.859 1.07 0.000678 0.0544 0.99 1 0.899 1.11 0.0266 0.0542 0.624 1.03 0.923 1.14 ukb-melanoma-gwas-catalog all 187.8 Neoplasm of uncertain behavior of male genital organs Neoplasms Male 0.897 0.737 1.09 0.274 110 1100 FALSE 0.562249437179612 -0.109 0.0994 0.0598 0.257 0.816 1.06 0.638 1.77 -0.41 0.293 0.161 0.663 0.366 1.18 -0.277 0.281 0.324 0.758 0.431 1.32 ukb-melanoma-gwas-catalog all 189 Cancer of urinary organs (incl. kidney and bladder) Neoplasms Both 0.976 0.945 1.01 0.13 4183 41830 FALSE 0.886056647693163 -0.0246 0.0163 -0.00567 0.0454 0.901 0.994 0.91 1.09 -0.0685 0.0461 0.137 0.934 0.853 1.02 -0.0373 0.0459 0.416 0.963 0.88 1.05 ukb-melanoma-gwas-catalog all 189.1 Cancer of kidney and renal pelvis Neoplasms Both 1.03 0.97 1.1 0.313 1075 10750 FALSE 0.504455662453552 0.0323 0.032 -0.0902 0.0932 0.333 0.914 0.761 1.1 0.0587 0.09 0.514 1.06 0.889 1.27 0.091 0.0896 0.31 1.1 0.919 1.31 ukb-melanoma-gwas-catalog all 189.2 Cancer of bladder Neoplasms Both 0.958 0.918 0.999 0.0424 2424 24240 TRUE 1.37263414340727 -0.0434 0.0214 0.0136 0.0587 0.817 1.01 0.903 1.14 -0.128 0.0607 0.0352 0.88 0.781 0.991 -0.0938 0.0603 0.12 0.91 0.809 1.02 ukb-melanoma-gwas-catalog all 189.4 Malignant neoplasm of other urinary organs Neoplasms Both 0.987 0.831 1.17 0.882 144 1440 FALSE 0.0545314148681803 -0.0129 0.0869 0.162 0.234 0.489 1.18 0.741 1.87 -0.311 0.26 0.231 0.733 0.434 1.22 0.0203 0.241 0.933 1.02 0.632 1.65 ukb-melanoma-gwas-catalog all 189.11 Malignant neoplasm of kidney, except pelvis Neoplasms Both 1.04 0.973 1.11 0.26 1032 10320 FALSE 0.585026652029182 0.0368 0.0327 -0.107 0.0956 0.261 0.898 0.744 1.08 0.0651 0.0918 0.478 1.07 0.891 1.28 0.11 0.0912 0.228 1.12 0.933 1.34 ukb-melanoma-gwas-catalog all 189.12 Malignant neoplasm of renal pelvis Neoplasms Both 0.918 0.711 1.18 0.506 66 660 FALSE 0.295849483160201 -0.0851 0.128 0.00458 0.341 0.989 1 0.506 1.99 -0.227 0.359 0.528 0.797 0.383 1.63 -0.201 0.353 0.569 0.818 0.398 1.66 ukb-melanoma-gwas-catalog all 189.21 Malignant neoplasm of bladder Neoplasms Both 0.955 0.914 0.999 0.0442 2148 21480 TRUE 1.35457773065091 -0.0457 0.0227 0.0324 0.0622 0.602 1.03 0.914 1.17 -0.137 0.0647 0.0349 0.872 0.768 0.99 -0.0933 0.0642 0.146 0.911 0.803 1.03 ukb-melanoma-gwas-catalog all 190 Cancer of eye Neoplasms Both 1.06 0.909 1.24 0.445 176 1760 FALSE 0.351639989019068 0.0602 0.0789 0.445 0.224 0.0468 1.56 1.01 2.45 -0.0259 0.244 0.915 0.974 0.598 1.59 0.437 0.229 0.0558 1.55 0.989 2.45 ukb-melanoma-gwas-catalog all 191 Manlignant and unknown neoplasms of brain and nervous system Neoplasms Both 1.06 0.984 1.15 0.121 692 6920 FALSE 0.91721462968355 0.0617 0.0398 0.0403 0.119 0.734 1.04 0.824 1.32 0.318 0.112 0.00455 1.37 1.1 1.71 0.15 0.116 0.195 1.16 0.926 1.46 ukb-melanoma-gwas-catalog all 191.1 Cancer of brain and nervous system Neoplasms Both 1.08 0.992 1.18 0.074 568 5680 FALSE 1.13076828026902 0.0785 0.0439 0.12 0.131 0.36 1.13 0.872 1.46 0.382 0.125 0.00213 1.47 1.15 1.88 0.162 0.13 0.212 1.18 0.911 1.52 ukb-melanoma-gwas-catalog all 191.11 Cancer of brain Neoplasms Both 1.09 0.992 1.19 0.0741 524 5240 FALSE 1.13018179202067 0.0816 0.0457 0.147 0.137 0.282 1.16 0.886 1.52 0.386 0.13 0.00307 1.47 1.14 1.91 0.191 0.135 0.159 1.21 0.928 1.58 ukb-melanoma-gwas-catalog all 193 Thyroid cancer Neoplasms Both 1.05 0.945 1.18 0.342 358 3580 FALSE 0.465973893943865 0.0527 0.0555 -0.00916 0.16 0.954 0.991 0.723 1.36 0.121 0.155 0.434 1.13 0.832 1.53 0.0657 0.158 0.677 1.07 0.783 1.46 ukb-melanoma-gwas-catalog all 194 Cancer of other endocrine glands Neoplasms Both 1.07 0.864 1.32 0.542 95 950 FALSE 0.266000713461613 0.0649 0.106 0.104 0.309 0.736 1.11 0.599 2.07 0.192 0.303 0.525 1.21 0.664 2.23 0.171 0.302 0.571 1.19 0.652 2.18 ukb-melanoma-gwas-catalog all 195 Cancer, suspected or other Neoplasms Both 1.07 1.05 1.09 2.42e-17 17028 165982 TRUE 16.6161846340196 0.0683 0.00806 0.0278 0.0234 0.235 1.03 0.982 1.08 0.0797 0.0231 0.000573 1.08 1.03 1.13 0.161 0.0228 1.56e-12 1.17 1.12 1.23 ukb-melanoma-gwas-catalog all 195.1 Malignant neoplasm, other Neoplasms Both 1.07 1.06 1.09 1.41e-17 16305 159816 TRUE 16.8507808873446 0.0703 0.00824 0.029 0.0239 0.225 1.03 0.982 1.08 0.081 0.0237 0.000614 1.08 1.04 1.14 0.168 0.0233 5.51e-13 1.18 1.13 1.24 ukb-melanoma-gwas-catalog all 197 Chemotherapy Neoplasms Both 1.02 1 1.03 0.0114 21492 213706 TRUE 1.94309514866353 0.0182 0.00717 0.0299 0.0204 0.142 1.03 0.99 1.07 0.0362 0.0204 0.076 1.04 0.996 1.08 0.0502 0.0204 0.0137 1.05 1.01 1.09 ukb-melanoma-gwas-catalog all 198 Secondary malignant neoplasm Neoplasms Both 1.03 1.01 1.05 0.00791 9585 95830 TRUE 2.10182351650232 0.0285 0.0107 0.0113 0.0307 0.714 1.01 0.952 1.07 0.0582 0.0304 0.0555 1.06 0.999 1.13 0.0492 0.0305 0.107 1.05 0.989 1.12 ukb-melanoma-gwas-catalog all 198.1 Secondary malignancy of lymph nodes Neoplasms Both 1.03 1 1.06 0.0341 5355 53549 TRUE 1.4672456210075 0.0305 0.0144 0.00941 0.041 0.818 1.01 0.932 1.09 0.0512 0.0406 0.208 1.05 0.972 1.14 0.0362 0.0409 0.376 1.04 0.957 1.12 ukb-melanoma-gwas-catalog all 198.2 Secondary malignancy of respiratory organs Neoplasms Both 1.02 0.979 1.07 0.307 2263 22619 FALSE 0.512861624522813 0.0226 0.0221 0.00421 0.0631 0.947 1 0.887 1.14 0.082 0.062 0.186 1.09 0.961 1.23 0.0164 0.0632 0.795 1.02 0.898 1.15 ukb-melanoma-gwas-catalog all 198.3 Secondary malignant neoplasm of digestive systems Neoplasms Both 0.978 0.928 1.03 0.409 1542 15416 FALSE 0.388276691992658 -0.0221 0.0268 -0.0369 0.0747 0.621 0.964 0.832 1.12 -0.0661 0.0751 0.379 0.936 0.808 1.08 -0.0791 0.0757 0.296 0.924 0.796 1.07 ukb-melanoma-gwas-catalog all 198.4 Secondary malignant neoplasm of liver Neoplasms Both 1.03 0.986 1.07 0.199 2661 26602 FALSE 0.701146923590293 0.0262 0.0204 0.022 0.0582 0.705 1.02 0.912 1.15 0.0901 0.0574 0.117 1.09 0.978 1.22 0.0265 0.0583 0.65 1.03 0.916 1.15 ukb-melanoma-gwas-catalog all 198.5 Secondary malignancy of brain/spine Neoplasms Both 1.07 1 1.15 0.0487 846 8460 TRUE 1.31247103878537 0.071 0.036 0.0166 0.105 0.875 1.02 0.827 1.25 0.161 0.102 0.116 1.17 0.961 1.44 0.132 0.103 0.2 1.14 0.932 1.4 ukb-melanoma-gwas-catalog all 198.6 Secondary malignancy of bone Neoplasms Both 1.03 0.983 1.07 0.227 2156 21553 FALSE 0.643974142806877 0.0273 0.0226 0.0223 0.0644 0.729 1.02 0.901 1.16 0.0182 0.0645 0.778 1.02 0.897 1.16 0.0698 0.064 0.275 1.07 0.946 1.22 ukb-melanoma-gwas-catalog all 198.7 Secondary malignant neoplasm of skin Neoplasms Both 1.09 0.936 1.26 0.267 187 1869 FALSE 0.573488738635425 0.0846 0.0762 0.251 0.215 0.242 1.29 0.842 1.98 0.0729 0.223 0.744 1.08 0.691 1.68 0.108 0.222 0.628 1.11 0.718 1.73 ukb-melanoma-gwas-catalog all 199 Neoplasm of uncertain behavior Neoplasms Both 1.03 0.979 1.09 0.23 1433 14330 FALSE 0.638272163982407 0.0333 0.0278 0.078 0.0789 0.323 1.08 0.926 1.26 0.0462 0.0796 0.562 1.05 0.896 1.22 0.0834 0.079 0.291 1.09 0.931 1.27 ukb-melanoma-gwas-catalog all 199.4 Neurofibromatosis Neoplasms Both 0.8 0.644 0.992 0.0408 95 950 TRUE 1.38933983691012 -0.223 0.109 -0.337 0.285 0.238 0.714 0.402 1.25 -0.322 0.284 0.257 0.725 0.409 1.27 -0.697 0.31 0.0247 0.498 0.263 0.913 ukb-melanoma-gwas-catalog all 200 Myeloproliferative disease Neoplasms Both 1.06 0.997 1.13 0.0628 1000 10000 FALSE 1.2020403562628 0.0616 0.0331 0.138 0.0956 0.148 1.15 0.952 1.39 0.137 0.0957 0.153 1.15 0.95 1.38 0.172 0.0952 0.0713 1.19 0.985 1.43 ukb-melanoma-gwas-catalog all 200.1 Polycythemia vera Neoplasms Both 1.14 1.03 1.26 0.0138 390 3900 TRUE 1.86012091359876 0.13 0.0529 0.358 0.153 0.0194 1.43 1.06 1.94 0.19 0.158 0.23 1.21 0.886 1.65 0.292 0.155 0.0601 1.34 0.988 1.82 ukb-melanoma-gwas-catalog all 201 Hodgkin's disease Neoplasms Both 1.04 0.913 1.18 0.577 261 2610 FALSE 0.238824186844269 0.036 0.0646 0.369 0.184 0.0445 1.45 1.01 2.09 0.0672 0.196 0.731 1.07 0.726 1.58 0.268 0.187 0.152 1.31 0.906 1.9 ukb-melanoma-gwas-catalog all 202 Cancer of other lymphoid, histiocytic tissue Neoplasms Both 1.01 0.964 1.05 0.764 2297 22970 FALSE 0.11690664142431 0.00659 0.0219 0.0451 0.062 0.466 1.05 0.926 1.18 0.0151 0.0624 0.809 1.02 0.898 1.15 0.0356 0.0623 0.568 1.04 0.917 1.17 ukb-melanoma-gwas-catalog all 202.2 Non-Hodgkins lymphoma Neoplasms Both 1.01 0.965 1.06 0.612 1821 18210 FALSE 0.213248577854439 0.0125 0.0246 0.0387 0.0697 0.579 1.04 0.907 1.19 -0.00174 0.0704 0.98 0.998 0.87 1.15 0.0551 0.0697 0.429 1.06 0.922 1.21 ukb-melanoma-gwas-catalog all 202.21 Nodular lymphoma Neoplasms Both 0.949 0.853 1.06 0.341 370 3700 FALSE 0.467245621007502 -0.052 0.0546 -0.0273 0.149 0.854 0.973 0.725 1.3 -0.283 0.158 0.0733 0.753 0.55 1.03 -0.0492 0.15 0.743 0.952 0.708 1.28 ukb-melanoma-gwas-catalog all 202.24 Large cell lymphoma Neoplasms Both 1.06 0.973 1.15 0.184 584 5840 FALSE 0.735182176990464 0.0576 0.0434 0.114 0.124 0.362 1.12 0.877 1.43 0.0278 0.126 0.826 1.03 0.802 1.32 0.201 0.123 0.103 1.22 0.96 1.56 ukb-melanoma-gwas-catalog all 204 Leukemia Neoplasms Both 1.06 1 1.11 0.0354 1696 16954 TRUE 1.45099673797421 0.0536 0.0255 -0.0051 0.0731 0.944 0.995 0.862 1.15 0.0454 0.0725 0.531 1.05 0.908 1.21 0.0857 0.0719 0.233 1.09 0.946 1.25 ukb-melanoma-gwas-catalog all 204.1 Lymphoid leukemia Neoplasms Both 1.11 1.02 1.21 0.0133 587 5864 TRUE 1.87614835903291 0.107 0.0432 0.191 0.127 0.133 1.21 0.944 1.55 0.204 0.127 0.107 1.23 0.957 1.58 0.276 0.125 0.0273 1.32 1.03 1.69 ukb-melanoma-gwas-catalog all 204.2 Myeloid leukemia Neoplasms Both 1.06 0.969 1.17 0.19 486 4860 FALSE 0.721246399047171 0.0622 0.0475 -0.0542 0.139 0.697 0.947 0.72 1.25 0.158 0.133 0.235 1.17 0.902 1.52 0.104 0.135 0.442 1.11 0.851 1.45 ukb-melanoma-gwas-catalog all 204.4 Multiple myeloma Neoplasms Both 1.02 0.939 1.12 0.588 559 5590 FALSE 0.230622673923862 0.024 0.0443 -0.102 0.125 0.415 0.903 0.705 1.15 -0.0883 0.125 0.481 0.916 0.715 1.17 0.00603 0.123 0.961 1.01 0.79 1.28 ukb-melanoma-gwas-catalog all 204.11 Lymphoid leukemia, acute Neoplasms Both 1.11 0.852 1.44 0.427 60 600 FALSE 0.369572124974976 0.104 0.131 0.164 0.381 0.666 1.18 0.548 2.55 -0.00523 0.379 0.989 0.995 0.462 2.15 0.0027 0.381 0.994 1 0.466 2.17 ukb-melanoma-gwas-catalog all 204.12 Lymphoid leukemia, chronic Neoplasms Both 1.1 1.01 1.21 0.0368 514 5134 TRUE 1.43415218132648 0.0963 0.0461 0.261 0.136 0.0551 1.3 0.994 1.7 0.27 0.136 0.047 1.31 1 1.72 0.31 0.135 0.022 1.36 1.05 1.78 ukb-melanoma-gwas-catalog all 204.21 Myeloid leukemia, acute Neoplasms Both 1.09 0.972 1.22 0.139 336 3360 FALSE 0.856985199745905 0.0844 0.057 -0.0551 0.17 0.746 0.946 0.676 1.32 0.279 0.159 0.0798 1.32 0.967 1.81 0.138 0.164 0.399 1.15 0.832 1.59 ukb-melanoma-gwas-catalog all 204.22 Myeloid leukemia, chronic Neoplasms Both 1.09 0.924 1.28 0.306 157 1570 FALSE 0.51427857351842 0.0852 0.0832 -0.00794 0.242 0.974 0.992 0.613 1.61 0.0422 0.239 0.86 1.04 0.648 1.68 0.225 0.231 0.33 1.25 0.794 1.99 ukb-melanoma-gwas-catalog all 208 Benign neoplasm of colon Neoplasms Both 1.01 0.995 1.02 0.192 19890 192225 FALSE 0.71669877129645 0.00974 0.00747 0.00133 0.0212 0.95 1 0.961 1.04 0.0201 0.0211 0.341 1.02 0.979 1.06 0.0205 0.0212 0.333 1.02 0.979 1.06 ukb-melanoma-gwas-catalog all 210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms Both 1.04 0.977 1.11 0.209 981 9810 FALSE 0.679853713888946 0.0421 0.0335 -0.0409 0.0957 0.669 0.96 0.795 1.16 -0.0321 0.0957 0.737 0.968 0.802 1.17 0.0859 0.0931 0.357 1.09 0.908 1.31 ukb-melanoma-gwas-catalog all 211 Benign neoplasm of other parts of digestive system Neoplasms Both 0.994 0.966 1.02 0.669 5256 52560 FALSE 0.174573882232177 -0.0062 0.0145 -0.0716 0.041 0.0805 0.931 0.859 1.01 -0.0235 0.0406 0.562 0.977 0.902 1.06 -0.0471 0.0409 0.249 0.954 0.881 1.03 ukb-melanoma-gwas-catalog all 212 Benign neoplasm of respiratory and intrathoracic organs Neoplasms Both 0.994 0.89 1.11 0.917 348 3480 FALSE 0.0376306643299789 -0.00589 0.0562 0.0737 0.154 0.633 1.08 0.795 1.46 -0.0832 0.159 0.602 0.92 0.671 1.26 -0.092 0.161 0.568 0.912 0.664 1.25 ukb-melanoma-gwas-catalog all 213 Benign neoplasm of bone and articular cartilage Neoplasms Both 1.02 0.909 1.14 0.738 320 3200 FALSE 0.131943638176958 0.0196 0.0586 -0.011 0.166 0.947 0.989 0.713 1.37 0.00565 0.165 0.973 1.01 0.726 1.39 0.0278 0.165 0.866 1.03 0.743 1.42 ukb-melanoma-gwas-catalog all 214 Lipoma Neoplasms Both 1.01 0.986 1.04 0.361 6246 62460 FALSE 0.442492798094342 0.0122 0.0133 -0.0245 0.0378 0.516 0.976 0.906 1.05 -0.00393 0.0376 0.917 0.996 0.925 1.07 0.0207 0.0375 0.581 1.02 0.949 1.1 ukb-melanoma-gwas-catalog all 214.1 Lipoma of skin and subcutaneous tissue Neoplasms Both 1.02 0.989 1.05 0.216 4593 45930 FALSE 0.665546248849069 0.0192 0.0155 -0.0275 0.0442 0.533 0.973 0.892 1.06 0.00432 0.0439 0.922 1 0.921 1.09 0.0314 0.0437 0.472 1.03 0.947 1.12 ukb-melanoma-gwas-catalog all 215 Other benign neoplasm of connective and other soft tissue Neoplasms Both 1.03 0.968 1.1 0.35 1109 11090 FALSE 0.455931955649724 0.0295 0.0315 -0.135 0.09 0.135 0.874 0.732 1.04 -0.082 0.089 0.357 0.921 0.773 1.1 0.033 0.0869 0.704 1.03 0.871 1.23 ukb-melanoma-gwas-catalog all 216 Benign neoplasm of skin Neoplasms Both 1.1 1.07 1.13 3.17e-15 7679 76785 TRUE 14.4989407377822 0.0945 0.012 0.118 0.0348 0.000675 1.13 1.05 1.21 0.116 0.0349 0.000891 1.12 1.05 1.2 0.224 0.0342 5.61e-11 1.25 1.17 1.34 ukb-melanoma-gwas-catalog all 217 Vascular hamartomas and non-neoplastic nevi Neoplasms Both 1.03 0.954 1.12 0.418 649 6490 FALSE 0.378823718224965 0.0334 0.0412 0.173 0.116 0.135 1.19 0.947 1.49 -0.0616 0.122 0.613 0.94 0.74 1.19 0.16 0.116 0.171 1.17 0.933 1.48 ukb-melanoma-gwas-catalog all 217.1 Nevus, non-neoplastic Neoplasms Both 1.03 0.947 1.12 0.482 597 5970 FALSE 0.31695296176115 0.0302 0.043 0.169 0.121 0.162 1.18 0.934 1.5 -0.0361 0.126 0.774 0.965 0.753 1.24 0.126 0.122 0.3 1.13 0.893 1.44 ukb-melanoma-gwas-catalog all 218 Benign neoplasm of uterus Neoplasms Female 1.03 1.01 1.05 0.00348 10507 105069 TRUE 2.45842075605342 0.03 0.0103 0.0351 0.0292 0.23 1.04 0.978 1.1 0.0492 0.0292 0.0915 1.05 0.992 1.11 0.0644 0.0291 0.0271 1.07 1.01 1.13 ukb-melanoma-gwas-catalog all 218.1 Uterine leiomyoma Neoplasms Female 1.03 1.01 1.05 0.00212 10245 102449 TRUE 2.67366413907125 0.0319 0.0104 0.0353 0.0296 0.233 1.04 0.978 1.1 0.044 0.0296 0.137 1.04 0.986 1.11 0.0671 0.0295 0.0229 1.07 1.01 1.13 ukb-melanoma-gwas-catalog all 218.2 Other benign neoplasm of uterus Neoplasms Female 0.938 0.84 1.05 0.25 353 3530 FALSE 0.602059991327962 -0.0644 0.056 0.0318 0.156 0.838 1.03 0.759 1.4 0.119 0.154 0.44 1.13 0.832 1.53 -0.165 0.165 0.315 0.848 0.612 1.17 ukb-melanoma-gwas-catalog all 220 Benign neoplasm of ovary Neoplasms Female 1.01 0.956 1.06 0.739 1476 14760 FALSE 0.131355561605174 0.00913 0.0274 0.0656 0.077 0.395 1.07 0.918 1.24 0.0169 0.0778 0.828 1.02 0.873 1.18 0.031 0.078 0.691 1.03 0.885 1.2 ukb-melanoma-gwas-catalog all 221 Benign neoplasm of other female genital organs Neoplasms Female 0.939 0.817 1.08 0.372 220 2200 FALSE 0.429457060118102 -0.063 0.0706 -0.268 0.197 0.173 0.765 0.517 1.13 -0.246 0.195 0.207 0.782 0.531 1.15 -0.157 0.192 0.413 0.855 0.584 1.25 ukb-melanoma-gwas-catalog all 222 Benign neoplasm of male genital organs Neoplasms Male 0.876 0.743 1.03 0.11 160 1600 FALSE 0.958607314841775 -0.133 0.0831 -0.0172 0.219 0.937 0.983 0.637 1.52 -0.135 0.224 0.549 0.874 0.559 1.36 -0.452 0.243 0.0631 0.636 0.389 1.02 ukb-melanoma-gwas-catalog all 223 Benign neoplasm of kidney and other urinary organs Neoplasms Both 0.939 0.802 1.1 0.429 174 1740 FALSE 0.367542707815276 -0.063 0.0796 0.194 0.222 0.383 1.21 0.783 1.89 0.0654 0.226 0.772 1.07 0.683 1.67 -0.00625 0.233 0.979 0.994 0.625 1.58 ukb-melanoma-gwas-catalog all 224 Benign neoplasm of eye Neoplasms Both 0.926 0.772 1.11 0.404 130 1300 FALSE 0.393618634889395 -0.0766 0.0917 0.00336 0.252 0.989 1 0.608 1.65 -0.0617 0.254 0.808 0.94 0.567 1.56 -0.129 0.26 0.621 0.879 0.522 1.47 ukb-melanoma-gwas-catalog all 224.1 Benign neoplasm of eye, uveal Neoplasms Both 1.04 0.813 1.34 0.726 68 680 FALSE 0.139063379299906 0.0438 0.125 0.0372 0.346 0.914 1.04 0.518 2.08 -0.193 0.363 0.595 0.825 0.394 1.71 0.0937 0.346 0.786 1.1 0.549 2.21 ukb-melanoma-gwas-catalog all 225 Benign neoplasm of brain and other parts of nervous system Neoplasms Both 0.996 0.927 1.07 0.912 830 8300 FALSE 0.0400051616715838 -0.00403 0.0365 0.0428 0.103 0.678 1.04 0.853 1.28 -0.014 0.104 0.893 0.986 0.803 1.21 0.0458 0.103 0.657 1.05 0.855 1.28 ukb-melanoma-gwas-catalog all 225.1 Benign neoplasm of brain, cranial nerves, meninges Neoplasms Both 1 0.93 1.08 0.975 776 7760 FALSE 0.0109953843014632 0.0012 0.0378 0.0654 0.106 0.538 1.07 0.866 1.32 -0.0207 0.109 0.848 0.979 0.791 1.21 0.0705 0.107 0.508 1.07 0.87 1.32 ukb-melanoma-gwas-catalog all 225.2 Benign neoplasm of spinal cord, meninges Neoplasms Both 0.938 0.717 1.23 0.632 59 590 FALSE 0.199282921717615 -0.0644 0.134 -0.377 0.383 0.326 0.686 0.311 1.47 -0.064 0.355 0.857 0.938 0.46 1.91 -0.204 0.374 0.586 0.815 0.379 1.72 ukb-melanoma-gwas-catalog all 226 Benign neoplasm of thyroid glands Neoplasms Both 1.03 0.914 1.17 0.602 285 2850 FALSE 0.220403508742175 0.0324 0.062 0.049 0.177 0.782 1.05 0.74 1.49 -0.0513 0.18 0.775 0.95 0.666 1.35 0.171 0.172 0.322 1.19 0.845 1.67 ukb-melanoma-gwas-catalog all 227 Benign neoplasm of other endocrine glands and related structures Neoplasms Both 1.06 0.991 1.14 0.0896 878 8780 FALSE 1.04769199033787 0.0602 0.0355 0.0115 0.103 0.911 1.01 0.826 1.24 0.161 0.0998 0.107 1.17 0.966 1.43 0.104 0.101 0.306 1.11 0.909 1.35 ukb-melanoma-gwas-catalog all 227.1 Benign neoplasm of adrenal gland Neoplasms Both 1.09 0.938 1.27 0.255 186 1860 FALSE 0.593459819566045 0.0875 0.0768 0.0512 0.223 0.818 1.05 0.677 1.64 0.327 0.214 0.127 1.39 0.911 2.13 0.0515 0.224 0.818 1.05 0.675 1.64 ukb-melanoma-gwas-catalog all 227.2 Benign neoplasm of parathyroid gland Neoplasms Both 1.06 0.956 1.18 0.257 371 3710 FALSE 0.590066876668705 0.0617 0.0544 0.00768 0.157 0.961 1.01 0.74 1.37 0.0382 0.156 0.806 1.04 0.764 1.41 0.161 0.152 0.292 1.17 0.87 1.59 ukb-melanoma-gwas-catalog all 227.3 Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch) Neoplasms Both 1.01 0.901 1.14 0.827 311 3110 FALSE 0.0824944904474534 0.013 0.0594 -0.0377 0.17 0.825 0.963 0.688 1.35 0.156 0.163 0.34 1.17 0.848 1.61 -0.0348 0.171 0.839 0.966 0.689 1.35 ukb-melanoma-gwas-catalog all 228 Hemangioma and lymphangioma, any site Neoplasms Both 1.03 0.976 1.08 0.297 1602 16020 FALSE 0.527243550682788 0.0273 0.0262 -0.0549 0.0748 0.462 0.947 0.817 1.1 0.0174 0.0737 0.813 1.02 0.881 1.18 0.0067 0.0739 0.928 1.01 0.871 1.16 ukb-melanoma-gwas-catalog all 229 Benign neoplasm of unspecified sites Neoplasms Both 1.02 0.981 1.07 0.28 2400 23998 FALSE 0.552841968657781 0.0232 0.0215 0.157 0.0606 0.0095 1.17 1.04 1.32 0.0516 0.0621 0.406 1.05 0.932 1.19 0.094 0.0617 0.128 1.1 0.973 1.24 ukb-melanoma-gwas-catalog all 240 Simple and unspecified goiter Endocrine/metabolic Both 0.964 0.886 1.05 0.397 602 6020 FALSE 0.401209493236885 -0.0363 0.0428 0.0562 0.118 0.634 1.06 0.839 1.33 -0.131 0.123 0.287 0.877 0.688 1.12 -0.00634 0.12 0.958 0.994 0.785 1.26 ukb-melanoma-gwas-catalog all 241 Nontoxic nodular goiter Endocrine/metabolic Both 1 0.945 1.07 0.886 1142 11420 FALSE 0.0525662781129492 0.00446 0.0311 -0.00858 0.088 0.922 0.991 0.834 1.18 0.0417 0.0871 0.633 1.04 0.879 1.24 -0.0211 0.0888 0.812 0.979 0.822 1.17 ukb-melanoma-gwas-catalog all 241.1 Nontoxic uninodular goiter Endocrine/metabolic Both 0.944 0.858 1.04 0.234 472 4720 FALSE 0.630784142589857 -0.0576 0.0484 0.0925 0.134 0.49 1.1 0.843 1.43 0.0962 0.134 0.472 1.1 0.846 1.43 -0.135 0.143 0.345 0.874 0.659 1.16 ukb-melanoma-gwas-catalog all 241.2 Nontoxic multinodular goiter Endocrine/metabolic Both 1.06 0.975 1.14 0.181 679 6790 FALSE 0.742321425130815 0.0539 0.0403 -0.0474 0.116 0.684 0.954 0.759 1.2 0.0796 0.113 0.481 1.08 0.867 1.35 0.0358 0.114 0.754 1.04 0.828 1.3 ukb-melanoma-gwas-catalog all 242 Thyrotoxicosis with or without goiter Endocrine/metabolic Both 0.997 0.95 1.05 0.887 1849 18490 FALSE 0.0520763801682736 -0.00348 0.0245 0.0415 0.0685 0.544 1.04 0.911 1.19 -0.0349 0.0698 0.617 0.966 0.842 1.11 0.0102 0.0693 0.883 1.01 0.882 1.16 ukb-melanoma-gwas-catalog all 242.1 Graves' disease Endocrine/metabolic Both 0.961 0.873 1.06 0.424 456 4560 FALSE 0.372634143407267 -0.0394 0.0492 0.268 0.135 0.0472 1.31 1 1.71 -0.0757 0.146 0.603 0.927 0.695 1.23 0.0592 0.142 0.676 1.06 0.803 1.4 ukb-melanoma-gwas-catalog all 242.2 Toxic multinodular goiter Endocrine/metabolic Both 0.984 0.793 1.22 0.886 91 910 FALSE 0.0525662781129492 -0.0157 0.109 -0.18 0.298 0.546 0.835 0.459 1.51 -0.174 0.302 0.564 0.84 0.458 1.53 -0.158 0.3 0.598 0.854 0.467 1.55 ukb-melanoma-gwas-catalog all 242.3 Exophthalmos Endocrine/metabolic Both 1.01 0.846 1.22 0.878 129 1290 FALSE 0.0565054840938974 0.0141 0.0914 0.267 0.251 0.287 1.31 0.796 2.16 0.0565 0.261 0.829 1.06 0.629 1.78 -0.0799 0.269 0.767 0.923 0.539 1.58 ukb-melanoma-gwas-catalog all 244 Hypothyroidism Endocrine/metabolic Both 0.992 0.975 1.01 0.342 14646 145476 FALSE 0.465973893943865 -0.00827 0.0087 0.00325 0.0245 0.894 1 0.956 1.05 -0.0017 0.0245 0.945 0.998 0.951 1.05 -0.0207 0.0247 0.402 0.98 0.933 1.03 ukb-melanoma-gwas-catalog all 244.1 Secondary hypothyroidism Endocrine/metabolic Both 1.02 0.96 1.09 0.502 1111 11110 FALSE 0.299296282854981 0.0212 0.0316 -0.161 0.0907 0.0752 0.851 0.712 1.02 0.00187 0.0874 0.983 1 0.844 1.19 -0.024 0.088 0.785 0.976 0.821 1.16 ukb-melanoma-gwas-catalog all 244.2 Acquired hypothyroidism Endocrine/metabolic Both 1.11 0.905 1.36 0.307 101 1010 FALSE 0.512861624522813 0.106 0.103 0.2 0.312 0.522 1.22 0.656 2.3 0.473 0.297 0.111 1.6 0.896 2.94 0.218 0.31 0.483 1.24 0.671 2.33 ukb-melanoma-gwas-catalog all 244.4 Hypothyroidism NOS Endocrine/metabolic Both 0.988 0.971 1.01 0.167 13961 139245 FALSE 0.777283528852417 -0.0123 0.00891 0.00428 0.025 0.864 1 0.956 1.05 -0.00438 0.0251 0.862 0.996 0.948 1.05 -0.0335 0.0253 0.185 0.967 0.92 1.02 ukb-melanoma-gwas-catalog all 245 Thyroiditis Endocrine/metabolic Both 0.93 0.825 1.05 0.239 294 2940 FALSE 0.621602099051862 -0.0722 0.0613 0.277 0.163 0.09 1.32 0.958 1.82 -0.237 0.183 0.195 0.789 0.548 1.13 -0.0494 0.176 0.778 0.952 0.672 1.35 ukb-melanoma-gwas-catalog all 245.2 Chronic thyroiditis Endocrine/metabolic Both 0.967 0.842 1.11 0.627 224 2240 FALSE 0.202732459169284 -0.034 0.07 0.293 0.19 0.123 1.34 0.923 1.96 -0.112 0.207 0.588 0.894 0.592 1.35 0.0436 0.201 0.828 1.04 0.702 1.56 ukb-melanoma-gwas-catalog all 245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic Both 0.963 0.836 1.11 0.604 211 2110 FALSE 0.218963061378868 -0.0374 0.0721 0.394 0.197 0.0459 1.48 1.01 2.2 0.013 0.214 0.951 1.01 0.663 1.55 0.0675 0.213 0.751 1.07 0.702 1.63 ukb-melanoma-gwas-catalog all 246 Other disorders of thyroid Endocrine/metabolic Both 0.923 0.832 1.02 0.126 403 4030 FALSE 0.899629454882437 -0.0802 0.0524 0.045 0.142 0.752 1.05 0.791 1.38 -0.113 0.148 0.444 0.893 0.667 1.19 -0.153 0.149 0.307 0.858 0.639 1.15 ukb-melanoma-gwas-catalog all 250 Diabetes mellitus Endocrine/metabolic Both 1.02 1 1.03 0.0143 19898 186647 TRUE 1.84466396253494 0.0183 0.00748 0.0297 0.0213 0.164 1.03 0.988 1.07 0.0674 0.0212 0.00145 1.07 1.03 1.12 0.0431 0.0214 0.0437 1.04 1 1.09 ukb-melanoma-gwas-catalog all 250.1 Type 1 diabetes Endocrine/metabolic Both 1.03 0.988 1.07 0.173 2657 26570 FALSE 0.761953896871205 0.0278 0.0204 0.0359 0.0578 0.534 1.04 0.926 1.16 0.0407 0.0577 0.481 1.04 0.93 1.17 0.0191 0.0582 0.743 1.02 0.909 1.14 ukb-melanoma-gwas-catalog all 250.2 Type 2 diabetes Endocrine/metabolic Both 1.02 1 1.03 0.0259 18671 176412 TRUE 1.58670023591875 0.0172 0.00772 0.0361 0.022 0.101 1.04 0.993 1.08 0.0694 0.0219 0.0015 1.07 1.03 1.12 0.0444 0.022 0.0442 1.05 1 1.09 ukb-melanoma-gwas-catalog all 250.4 Abnormal glucose Endocrine/metabolic Both 1.02 0.946 1.11 0.557 684 6840 FALSE 0.254144804826271 0.0236 0.0402 -0.149 0.117 0.202 0.862 0.685 1.08 0.0694 0.111 0.533 1.07 0.862 1.33 0.0346 0.113 0.76 1.04 0.829 1.29 ukb-melanoma-gwas-catalog all 250.5 Glycosuria or Acetonuria Endocrine/metabolic Both 1.01 0.84 1.21 0.938 131 1310 FALSE 0.0277971616209356 0.00713 0.0914 0.205 0.252 0.415 1.23 0.747 2.03 -0.0284 0.267 0.915 0.972 0.57 1.66 0.0684 0.26 0.792 1.07 0.639 1.8 ukb-melanoma-gwas-catalog all 250.6 Polyneuropathy in diabetes Endocrine/metabolic Both 0.985 0.883 1.1 0.79 354 3540 FALSE 0.102372908709559 -0.0149 0.0557 0.0515 0.155 0.739 1.05 0.776 1.43 -0.0613 0.158 0.698 0.941 0.688 1.28 -0.0278 0.157 0.86 0.973 0.713 1.33 ukb-melanoma-gwas-catalog all 250.7 Diabetic retinopathy Endocrine/metabolic Both 0.99 0.935 1.05 0.718 1335 13350 FALSE 0.1438755557577 -0.0104 0.0288 -0.106 0.0813 0.193 0.899 0.767 1.05 -0.0387 0.08 0.629 0.962 0.822 1.13 -0.0592 0.0806 0.462 0.943 0.805 1.1 ukb-melanoma-gwas-catalog all 250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic Both 0.923 0.807 1.06 0.239 239 2390 FALSE 0.621602099051862 -0.0802 0.0681 -0.205 0.189 0.278 0.815 0.56 1.18 -0.0937 0.183 0.609 0.911 0.633 1.31 -0.269 0.192 0.161 0.764 0.522 1.11 ukb-melanoma-gwas-catalog all 250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic Both 1.19 0.939 1.5 0.145 77 770 FALSE 0.838631997765025 0.172 0.118 0.173 0.344 0.614 1.19 0.598 2.39 0.193 0.348 0.58 1.21 0.602 2.46 0.359 0.335 0.284 1.43 0.739 2.84 ukb-melanoma-gwas-catalog all 250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic Both 1.22 0.996 1.5 0.0535 105 1050 FALSE 1.27164621797877 0.2 0.103 0.131 0.323 0.684 1.14 0.598 2.2 0.659 0.305 0.0309 1.93 1.06 3.61 0.58 0.301 0.0538 1.79 0.991 3.31 ukb-melanoma-gwas-catalog all 250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic Both 0.918 0.793 1.06 0.245 202 2020 FALSE 0.610833915635468 -0.0861 0.074 -0.435 0.202 0.0314 0.647 0.432 0.961 -0.448 0.203 0.0275 0.639 0.426 0.951 -0.361 0.2 0.0706 0.697 0.468 1.03 ukb-melanoma-gwas-catalog all 250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic Both 1 0.944 1.06 0.998 1294 12940 FALSE 0.000869458712628891 -5.93e-05 0.0292 -0.117 0.0831 0.159 0.889 0.755 1.05 -0.0164 0.0812 0.84 0.984 0.839 1.15 -0.0359 0.0818 0.661 0.965 0.822 1.13 ukb-melanoma-gwas-catalog all 250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic Both 0.996 0.914 1.09 0.93 575 5750 FALSE 0.0315170514460649 -0.00383 0.0438 0.143 0.123 0.243 1.15 0.907 1.47 0.00797 0.126 0.95 1.01 0.786 1.29 0.0808 0.125 0.517 1.08 0.848 1.39 ukb-melanoma-gwas-catalog all 250.41 Impaired fasting glucose Endocrine/metabolic Both 1.06 0.933 1.2 0.375 266 2660 FALSE 0.425968732272281 0.0572 0.0644 -0.164 0.188 0.383 0.849 0.584 1.23 0.0851 0.178 0.633 1.09 0.766 1.55 0.104 0.179 0.56 1.11 0.78 1.58 ukb-melanoma-gwas-catalog all 250.42 Other abnormal glucose Endocrine/metabolic Both 1.02 0.918 1.12 0.756 419 4190 FALSE 0.121478204498793 0.0159 0.0513 -0.0732 0.149 0.623 0.929 0.693 1.25 0.105 0.143 0.464 1.11 0.838 1.47 0.0816 0.146 0.575 1.09 0.815 1.45 ukb-melanoma-gwas-catalog all 251.1 Hypoglycemia Endocrine/metabolic Both 0.996 0.932 1.07 0.918 940 9395 FALSE 0.0371573187987575 -0.00354 0.0343 0.0601 0.096 0.531 1.06 0.88 1.28 0.0249 0.0968 0.797 1.03 0.848 1.24 -0.0298 0.0983 0.761 0.971 0.8 1.18 ukb-melanoma-gwas-catalog all 252 Disorders of parathyroid gland Endocrine/metabolic Both 1.07 1 1.15 0.0441 877 8770 TRUE 1.35556141053216 0.0713 0.0354 0.0543 0.103 0.598 1.06 0.863 1.29 0.125 0.102 0.221 1.13 0.927 1.38 0.182 0.1 0.0707 1.2 0.985 1.46 ukb-melanoma-gwas-catalog all 252.1 Hyperparathyroidism Endocrine/metabolic Both 1.08 1.01 1.17 0.0325 781 7810 TRUE 1.48811663902113 0.0802 0.0375 0.0541 0.109 0.62 1.06 0.852 1.31 0.0835 0.109 0.444 1.09 0.877 1.35 0.239 0.106 0.0235 1.27 1.03 1.56 ukb-melanoma-gwas-catalog all 252.2 Hypoparathyroidism Endocrine/metabolic Both 0.976 0.82 1.16 0.778 142 1420 FALSE 0.109020403010311 -0.0246 0.0874 0.227 0.242 0.349 1.25 0.778 2.04 0.21 0.246 0.393 1.23 0.759 2.01 -0.195 0.263 0.457 0.822 0.485 1.39 ukb-melanoma-gwas-catalog all 253 Disorders of the pituitary gland and its hypothalamic control Endocrine/metabolic Both 1.02 0.945 1.11 0.577 694 6940 FALSE 0.238824186844269 0.0222 0.0398 0.244 0.111 0.0282 1.28 1.03 1.59 0.0035 0.117 0.976 1 0.798 1.26 0.0863 0.115 0.454 1.09 0.869 1.37 ukb-melanoma-gwas-catalog all 253.1 Pituitary hyperfunction Endocrine/metabolic Both 0.975 0.839 1.13 0.737 189 1890 FALSE 0.132532512140949 -0.0255 0.076 0.463 0.21 0.0273 1.59 1.05 2.42 0.0928 0.224 0.679 1.1 0.704 1.72 0.0355 0.229 0.876 1.04 0.658 1.63 ukb-melanoma-gwas-catalog all 253.2 Pituitary hypofunction Endocrine/metabolic Both 1.05 0.924 1.19 0.456 263 2630 FALSE 0.341035157335565 0.0481 0.0645 0.133 0.183 0.468 1.14 0.796 1.64 0.0518 0.187 0.781 1.05 0.728 1.52 0.156 0.183 0.394 1.17 0.816 1.68 ukb-melanoma-gwas-catalog all 253.3 Diabetes insipidus Endocrine/metabolic Both 1 0.808 1.24 0.993 93 930 FALSE 0.00305075150461883 0.000995 0.107 0.124 0.299 0.679 1.13 0.625 2.06 0.0545 0.3 0.856 1.06 0.581 1.93 -0.0488 0.311 0.875 0.952 0.509 1.78 ukb-melanoma-gwas-catalog all 253.7 Other disorders of neurohypophysis Endocrine/metabolic Both 1.02 0.865 1.2 0.813 158 1580 FALSE 0.0899094544059319 0.0196 0.0829 -0.096 0.226 0.671 0.908 0.579 1.42 -0.299 0.237 0.208 0.741 0.46 1.18 -0.0863 0.227 0.703 0.917 0.585 1.44 ukb-melanoma-gwas-catalog all 253.11 Acromegaly and gigantism Endocrine/metabolic Both 0.901 0.727 1.11 0.329 95 950 FALSE 0.482804102050026 -0.105 0.107 -0.218 0.289 0.451 0.804 0.45 1.43 -0.168 0.287 0.558 0.845 0.475 1.49 -0.383 0.303 0.207 0.682 0.368 1.24 ukb-melanoma-gwas-catalog all 255 Disorders of adrenal glands Endocrine/metabolic Both 0.991 0.913 1.07 0.822 642 6420 FALSE 0.0851281824599496 -0.00932 0.0415 0.164 0.117 0.16 1.18 0.937 1.48 0.184 0.117 0.114 1.2 0.956 1.51 -0.0498 0.123 0.686 0.951 0.746 1.21 ukb-melanoma-gwas-catalog all 255.1 Adrenal hyperfunction Endocrine/metabolic Both 1.08 0.927 1.26 0.317 182 1820 FALSE 0.498940737782248 0.0778 0.0777 -0.269 0.228 0.237 0.764 0.484 1.2 0.0969 0.211 0.646 1.1 0.727 1.67 -0.0296 0.216 0.891 0.971 0.632 1.49 ukb-melanoma-gwas-catalog all 255.2 Adrenal hypofunction Endocrine/metabolic Both 0.946 0.849 1.05 0.316 364 3640 FALSE 0.500312917381596 -0.0552 0.0551 0.224 0.152 0.142 1.25 0.928 1.69 0.201 0.153 0.19 1.22 0.905 1.66 -0.17 0.168 0.311 0.844 0.605 1.17 ukb-melanoma-gwas-catalog all 255.11 Cushing's syndrome Endocrine/metabolic Both 0.99 0.808 1.21 0.926 103 1030 FALSE 0.0333890133180656 -0.0096 0.103 -0.198 0.283 0.485 0.821 0.464 1.44 -0.179 0.283 0.526 0.836 0.474 1.46 -0.172 0.282 0.542 0.842 0.478 1.47 ukb-melanoma-gwas-catalog all 255.12 Hyperaldosteronism Endocrine/metabolic Both 1.19 0.939 1.51 0.145 76 760 FALSE 0.838631997765025 0.174 0.12 -0.345 0.362 0.342 0.708 0.335 1.46 0.28 0.328 0.393 1.32 0.693 2.57 0.203 0.333 0.542 1.22 0.631 2.4 ukb-melanoma-gwas-catalog all 255.21 Glucocorticoid deficiency Endocrine/metabolic Both 0.944 0.847 1.05 0.299 361 3610 FALSE 0.52432881167557 -0.0574 0.0553 0.215 0.153 0.159 1.24 0.919 1.68 0.181 0.154 0.239 1.2 0.886 1.63 -0.17 0.168 0.31 0.843 0.605 1.17 ukb-melanoma-gwas-catalog all 256 Ovarian dysfunction Endocrine/metabolic Female 1.05 0.921 1.2 0.456 244 2440 FALSE 0.341035157335565 0.0499 0.0669 0.587 0.193 0.00235 1.8 1.24 2.65 0.206 0.207 0.321 1.23 0.816 1.86 0.322 0.202 0.111 1.38 0.929 2.07 ukb-melanoma-gwas-catalog all 256.4 Polycystic ovaries Endocrine/metabolic Female 1.06 0.918 1.22 0.43 209 2090 FALSE 0.366531544420413 0.057 0.0722 0.573 0.21 0.0063 1.77 1.18 2.71 0.251 0.224 0.262 1.29 0.827 2.01 0.341 0.218 0.119 1.41 0.916 2.18 ukb-melanoma-gwas-catalog all 257 Testicular dysfunction Endocrine/metabolic Male 1.03 0.878 1.21 0.699 163 1630 FALSE 0.155522824254319 0.0315 0.0814 -0.115 0.237 0.626 0.891 0.556 1.42 0.0257 0.23 0.911 1.03 0.651 1.62 0.11 0.226 0.625 1.12 0.715 1.75 ukb-melanoma-gwas-catalog all 257.1 Testicular hypofunction Endocrine/metabolic Male 1.03 0.873 1.22 0.72 154 1540 FALSE 0.142667503568732 0.03 0.0838 -0.0616 0.243 0.8 0.94 0.58 1.52 0.0556 0.237 0.815 1.06 0.662 1.69 0.12 0.234 0.606 1.13 0.711 1.8 ukb-melanoma-gwas-catalog all 258 Iatrogenic endocrine disorders Endocrine/metabolic Both 1.05 0.857 1.29 0.624 102 1020 FALSE 0.204815410317576 0.0507 0.103 0.0342 0.302 0.91 1.03 0.565 1.9 0.323 0.292 0.268 1.38 0.776 2.49 0.163 0.298 0.583 1.18 0.651 2.15 ukb-melanoma-gwas-catalog all 259 Other endocrine disorders Endocrine/metabolic Both 1.23 1.04 1.45 0.0157 152 1520 TRUE 1.80410034759077 0.205 0.0848 0.152 0.261 0.561 1.16 0.693 1.97 0.281 0.259 0.277 1.32 0.795 2.23 0.684 0.242 0.00465 1.98 1.24 3.23 ukb-melanoma-gwas-catalog all 260 Protein-calorie malnutrition Endocrine/metabolic Both 1.11 0.963 1.29 0.146 202 2019 FALSE 0.835647144215563 0.108 0.0741 0.241 0.212 0.255 1.27 0.838 1.94 0.205 0.215 0.342 1.23 0.802 1.89 0.258 0.214 0.227 1.29 0.85 1.98 ukb-melanoma-gwas-catalog all 261 Vitamin deficiency Endocrine/metabolic Both 1.02 0.961 1.08 0.521 1210 12100 FALSE 0.283162276700476 0.0194 0.0302 0.00342 0.0867 0.969 1 0.846 1.19 0.0657 0.0855 0.442 1.07 0.903 1.26 0.0737 0.0856 0.389 1.08 0.91 1.27 ukb-melanoma-gwas-catalog all 261.2 Vitamin B-complex deficiencies Endocrine/metabolic Both 1.01 0.938 1.09 0.772 755 7550 FALSE 0.112382699664264 0.0111 0.0383 -0.0292 0.109 0.789 0.971 0.783 1.2 0.0389 0.108 0.718 1.04 0.841 1.28 0.0469 0.108 0.664 1.05 0.847 1.3 ukb-melanoma-gwas-catalog all 261.4 Vitamin D deficiency Endocrine/metabolic Both 1.01 0.916 1.11 0.844 449 4490 FALSE 0.073657553374345 0.00974 0.0494 0.0807 0.141 0.568 1.08 0.821 1.43 0.13 0.14 0.353 1.14 0.865 1.5 0.0782 0.141 0.58 1.08 0.819 1.43 ukb-melanoma-gwas-catalog all 261.41 Rickets or osteomalacia Endocrine/metabolic Both 1.02 0.807 1.29 0.859 77 770 FALSE 0.0660068361687577 0.0211 0.118 -0.0191 0.33 0.954 0.981 0.505 1.9 0.0179 0.332 0.957 1.02 0.522 1.99 -0.00346 0.328 0.992 0.997 0.515 1.93 ukb-melanoma-gwas-catalog all 262 Mineral deficiency NEC Endocrine/metabolic Both 1.02 0.892 1.16 0.781 242 2420 FALSE 0.1073489661227 0.0187 0.0671 -0.267 0.197 0.175 0.765 0.517 1.13 0.00266 0.186 0.989 1 0.695 1.45 0.0586 0.184 0.75 1.06 0.738 1.53 ukb-melanoma-gwas-catalog all 269 Proteinuria Endocrine/metabolic Both 1.04 0.926 1.16 0.533 339 3390 FALSE 0.273272790973428 0.0354 0.0569 0.178 0.165 0.279 1.19 0.864 1.66 0.265 0.161 0.1 1.3 0.95 1.79 0.0989 0.167 0.555 1.1 0.794 1.54 ukb-melanoma-gwas-catalog all 270 Disorders of protein plasma/amino-acid transport and metabolism Endocrine/metabolic Both 1.04 0.925 1.17 0.505 304 3040 FALSE 0.296708621881339 0.0401 0.0601 0.271 0.176 0.123 1.31 0.929 1.86 0.309 0.174 0.0762 1.36 0.968 1.93 0.259 0.178 0.145 1.3 0.914 1.84 ukb-melanoma-gwas-catalog all 270.3 Disorders of plasma protein metabolism Endocrine/metabolic Both 1.05 0.923 1.19 0.463 261 2610 FALSE 0.334419008982047 0.0476 0.0648 0.308 0.188 0.102 1.36 0.94 1.98 0.258 0.19 0.175 1.29 0.891 1.89 0.294 0.191 0.124 1.34 0.922 1.96 ukb-melanoma-gwas-catalog all 270.32 Paraproteinemia Endocrine/metabolic Both 1.06 0.917 1.24 0.41 191 1910 FALSE 0.387216143280265 0.0625 0.0758 0.26 0.219 0.236 1.3 0.842 2.01 0.259 0.219 0.236 1.3 0.843 2.01 0.218 0.223 0.327 1.24 0.802 1.94 ukb-melanoma-gwas-catalog all 270.35 Macroglobulinemia Endocrine/metabolic Both 1.04 0.809 1.33 0.761 69 690 FALSE 0.118615343229427 0.0377 0.124 0.546 0.375 0.145 1.73 0.824 3.79 0.452 0.385 0.241 1.57 0.732 3.51 0.625 0.377 0.0975 1.87 0.889 4.11 ukb-melanoma-gwas-catalog all 271 Disorders of carbohydrate transport and metabolism Endocrine/metabolic Both 0.88 0.749 1.03 0.118 163 1621 FALSE 0.928117992693875 -0.128 0.0817 0.13 0.23 0.573 1.14 0.722 1.8 0.306 0.222 0.167 1.36 0.879 2.12 -0.281 0.251 0.263 0.755 0.455 1.24 ukb-melanoma-gwas-catalog all 271.3 Intestinal disaccharidase deficiencies and disaccharide malabsorption Endocrine/metabolic Both 0.884 0.743 1.05 0.161 141 1401 FALSE 0.79317412396815 -0.123 0.0877 0.204 0.246 0.407 1.23 0.754 2.01 0.316 0.241 0.188 1.37 0.855 2.22 -0.257 0.271 0.343 0.773 0.447 1.32 ukb-melanoma-gwas-catalog all 272 Disorders of lipoid metabolism Endocrine/metabolic Both 1.01 0.999 1.02 0.084 34960 235908 FALSE 1.07572071393812 0.01 0.0058 0.0218 0.0164 0.185 1.02 0.99 1.06 0.0174 0.0164 0.291 1.02 0.985 1.05 0.0323 0.0165 0.0495 1.03 1 1.07 ukb-melanoma-gwas-catalog all 272.1 Hyperlipidemia Endocrine/metabolic Both 1.01 0.999 1.02 0.0843 34878 235352 FALSE 1.07417242537526 0.01 0.00581 0.0219 0.0164 0.184 1.02 0.99 1.06 0.0183 0.0165 0.266 1.02 0.986 1.05 0.032 0.0165 0.0521 1.03 1 1.07 ukb-melanoma-gwas-catalog all 272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic Both 1.03 0.896 1.19 0.661 211 2110 FALSE 0.17979854051436 0.0316 0.0719 0.0297 0.206 0.886 1.03 0.685 1.55 -0.0901 0.21 0.668 0.914 0.601 1.39 0.21 0.197 0.287 1.23 0.837 1.83 ukb-melanoma-gwas-catalog all 272.11 Hypercholesterolemia Endocrine/metabolic Both 1.01 1 1.02 0.0572 32352 218140 FALSE 1.24260397120698 0.0115 0.00603 0.0196 0.0171 0.251 1.02 0.986 1.05 0.023 0.0171 0.178 1.02 0.99 1.06 0.0352 0.0171 0.0394 1.04 1 1.07 ukb-melanoma-gwas-catalog all 272.12 Hyperglyceridemia Endocrine/metabolic Both 1.21 0.923 1.58 0.159 58 580 FALSE 0.798602875679548 0.19 0.135 0.171 0.398 0.666 1.19 0.534 2.68 0.331 0.392 0.398 1.39 0.639 3.12 0.305 0.392 0.437 1.36 0.621 3.04 ukb-melanoma-gwas-catalog all 272.13 Mixed hyperlipidemia Endocrine/metabolic Both 0.918 0.781 1.08 0.296 164 1638 FALSE 0.528708288941061 -0.0853 0.0816 -0.00352 0.214 0.987 0.996 0.653 1.52 -0.446 0.238 0.0613 0.64 0.396 1.02 -0.249 0.229 0.278 0.78 0.493 1.22 ukb-melanoma-gwas-catalog all 274 Gout and other crystal arthropathies Endocrine/metabolic Both 1.04 1 1.07 0.0321 3742 37420 TRUE 1.49349496759513 0.0368 0.0172 0.0394 0.0492 0.424 1.04 0.945 1.15 0.0512 0.0491 0.297 1.05 0.956 1.16 0.109 0.0487 0.0253 1.11 1.01 1.23 ukb-melanoma-gwas-catalog all 274.1 Gout Endocrine/metabolic Both 1.03 0.995 1.07 0.0905 3176 31760 FALSE 1.0433514207948 0.0316 0.0187 0.0493 0.0532 0.354 1.05 0.946 1.17 0.0297 0.0536 0.579 1.03 0.927 1.14 0.118 0.0527 0.0249 1.13 1.02 1.25 ukb-melanoma-gwas-catalog all 274.2 Crystal arthropathies Endocrine/metabolic Both 1.08 0.996 1.18 0.0603 614 6140 FALSE 1.21968268785985 0.0795 0.0423 0.075 0.124 0.545 1.08 0.845 1.38 0.21 0.121 0.0809 1.23 0.974 1.57 0.169 0.122 0.165 1.18 0.932 1.51 ukb-melanoma-gwas-catalog all 274.11 Gouty arthropathy Endocrine/metabolic Both 1.03 0.843 1.25 0.798 111 1110 FALSE 0.0979971086492705 0.0252 0.0985 -0.22 0.276 0.426 0.803 0.46 1.39 -0.273 0.28 0.329 0.761 0.433 1.32 -0.0368 0.265 0.889 0.964 0.569 1.63 ukb-melanoma-gwas-catalog all 274.21 Chondrocalcinosis Endocrine/metabolic Both 1.08 0.994 1.18 0.0664 559 5590 FALSE 1.17783192063198 0.0814 0.0443 0.0934 0.13 0.471 1.1 0.851 1.42 0.194 0.127 0.126 1.21 0.946 1.56 0.2 0.127 0.117 1.22 0.951 1.57 ukb-melanoma-gwas-catalog all 275 Disorders of mineral metabolism Endocrine/metabolic Both 1.04 0.992 1.09 0.108 2116 21160 FALSE 0.96657624451305 0.0368 0.0229 -0.0437 0.0659 0.507 0.957 0.841 1.09 0.0639 0.0644 0.322 1.07 0.939 1.21 0.0743 0.0645 0.249 1.08 0.949 1.22 ukb-melanoma-gwas-catalog all 275.1 Disorders of iron metabolism Hematopoietic Both 1.05 0.968 1.14 0.242 657 6570 FALSE 0.616184634019569 0.0479 0.0409 -0.137 0.119 0.249 0.872 0.69 1.1 -0.0132 0.115 0.909 0.987 0.786 1.24 0.111 0.113 0.326 1.12 0.895 1.4 ukb-melanoma-gwas-catalog all 275.3 Disorders of magnesium metabolism Endocrine/metabolic Both 1.07 0.959 1.19 0.23 374 3740 FALSE 0.638272163982407 0.0651 0.0542 -0.000885 0.154 0.995 0.999 0.738 1.35 -0.0483 0.156 0.757 0.953 0.7 1.3 0.0931 0.151 0.538 1.1 0.815 1.48 ukb-melanoma-gwas-catalog all 275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic Both 1.03 0.967 1.09 0.384 1205 12050 FALSE 0.415668775632469 0.0264 0.0303 -0.0436 0.0875 0.618 0.957 0.806 1.14 0.117 0.0847 0.167 1.12 0.952 1.33 0.0402 0.0863 0.641 1.04 0.879 1.23 ukb-melanoma-gwas-catalog all 275.53 Disorders of phosphorus metabolism Endocrine/metabolic Both 1.11 0.951 1.3 0.181 172 1720 FALSE 0.742321425130815 0.106 0.0792 -0.26 0.243 0.286 0.771 0.473 1.25 0.16 0.221 0.469 1.17 0.759 1.82 0.205 0.219 0.35 1.23 0.797 1.9 ukb-melanoma-gwas-catalog all 276 Disorders of fluid, electrolyte, and acid-base balance Endocrine/metabolic Both 1.01 0.99 1.04 0.263 7342 73420 FALSE 0.580044251510242 0.0137 0.0123 0.0167 0.0346 0.629 1.02 0.95 1.09 -0.0115 0.0348 0.741 0.989 0.923 1.06 0.00857 0.0348 0.806 1.01 0.942 1.08 ukb-melanoma-gwas-catalog all 276.1 Electrolyte imbalance Endocrine/metabolic Both 1.02 0.991 1.06 0.158 4113 41130 FALSE 0.801342913045577 0.0232 0.0164 0.0546 0.0462 0.237 1.06 0.965 1.16 -0.00141 0.0468 0.976 0.999 0.911 1.09 0.0388 0.0466 0.405 1.04 0.949 1.14 ukb-melanoma-gwas-catalog all 276.4 Acid-base balance disorder Endocrine/metabolic Both 1.01 0.953 1.08 0.694 1160 11600 FALSE 0.158640529545145 0.0122 0.0309 0.0209 0.0877 0.812 1.02 0.86 1.21 0.0945 0.0864 0.274 1.1 0.928 1.3 -0.0257 0.0891 0.773 0.975 0.818 1.16 ukb-melanoma-gwas-catalog all 276.5 Hypovolemia Endocrine/metabolic Both 1.01 0.971 1.05 0.642 2825 28250 FALSE 0.192464971931147 0.00921 0.0198 -0.0107 0.0563 0.849 0.989 0.886 1.1 0.0495 0.0556 0.374 1.05 0.942 1.17 0.000986 0.0564 0.986 1 0.896 1.12 ukb-melanoma-gwas-catalog all 276.6 Fluid overload Endocrine/metabolic Both 1 0.908 1.1 0.989 455 4550 FALSE 0.0048037084028206 0.00065 0.0492 0.0215 0.134 0.872 1.02 0.785 1.33 -0.335 0.146 0.0217 0.715 0.535 0.952 -0.00129 0.135 0.992 0.999 0.765 1.3 ukb-melanoma-gwas-catalog all 276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic Both 1.05 0.922 1.2 0.443 239 2390 FALSE 0.35359627377693 0.0519 0.0676 0.118 0.198 0.55 1.13 0.762 1.67 0.337 0.189 0.0741 1.4 0.968 2.04 0.062 0.201 0.757 1.06 0.716 1.58 ukb-melanoma-gwas-catalog all 276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic Both 1.02 0.975 1.07 0.343 1822 18220 FALSE 0.464705879957229 0.0234 0.0246 0.022 0.0695 0.751 1.02 0.892 1.17 0.0133 0.0697 0.848 1.01 0.884 1.16 0.00059 0.07 0.993 1 0.872 1.15 ukb-melanoma-gwas-catalog all 276.13 Hyperpotassemia Endocrine/metabolic Both 1.05 0.982 1.12 0.152 977 9770 FALSE 0.818156412055227 0.0481 0.0336 0.182 0.0956 0.0562 1.2 0.995 1.45 0.126 0.0969 0.195 1.13 0.937 1.37 0.118 0.0974 0.224 1.13 0.93 1.36 ukb-melanoma-gwas-catalog all 276.14 Hypopotassemia Endocrine/metabolic Both 1.04 0.982 1.1 0.189 1422 14220 FALSE 0.723538195826756 0.0366 0.0278 0.0161 0.0781 0.837 1.02 0.872 1.18 -0.0858 0.08 0.283 0.918 0.784 1.07 0.055 0.078 0.481 1.06 0.907 1.23 ukb-melanoma-gwas-catalog all 276.41 Acidosis Endocrine/metabolic Both 1.03 0.964 1.09 0.412 1059 10590 FALSE 0.385102783966865 0.0265 0.0323 0.0692 0.092 0.452 1.07 0.895 1.28 0.122 0.0912 0.18 1.13 0.945 1.35 0.0144 0.0936 0.877 1.01 0.844 1.22 ukb-melanoma-gwas-catalog all 276.42 Alkalosis Endocrine/metabolic Both 0.875 0.719 1.06 0.178 112 1120 FALSE 0.749579997691106 -0.133 0.0988 -0.265 0.268 0.321 0.767 0.448 1.3 -0.108 0.26 0.677 0.897 0.534 1.5 -0.454 0.28 0.105 0.635 0.36 1.1 ukb-melanoma-gwas-catalog all 277 Other disorders of metabolism Endocrine/metabolic Both 0.996 0.93 1.07 0.902 905 9048 FALSE 0.0447934624580583 -0.00431 0.035 -0.0277 0.0979 0.777 0.973 0.802 1.18 -0.152 0.101 0.133 0.859 0.704 1.05 0.0559 0.0964 0.562 1.06 0.875 1.28 ukb-melanoma-gwas-catalog all 277.5 Other disorders of lipoid metabolism Endocrine/metabolic Both 1.19 0.938 1.5 0.145 75 750 FALSE 0.838631997765025 0.172 0.118 0.067 0.384 0.861 1.07 0.49 2.35 0.385 0.369 0.297 1.47 0.704 3.15 0.785 0.34 0.0208 2.19 1.13 4.44 ukb-melanoma-gwas-catalog all 277.51 Lipoprotein disorders Endocrine/metabolic Both 1.18 0.891 1.56 0.236 52 520 FALSE 0.627087997029893 0.166 0.14 0.0911 0.474 0.848 1.1 0.403 2.98 0.488 0.441 0.269 1.63 0.673 4.16 0.935 0.409 0.0223 2.55 1.16 6.1 ukb-melanoma-gwas-catalog all 278 Overweight, obesity and other hyperalimentation Endocrine/metabolic Both 1.01 0.995 1.03 0.149 10863 108629 FALSE 0.826813731587726 0.0145 0.0101 0.0476 0.0285 0.0947 1.05 0.992 1.11 0.0193 0.0287 0.5 1.02 0.964 1.08 0.021 0.0287 0.465 1.02 0.965 1.08 ukb-melanoma-gwas-catalog all 278.1 Obesity Endocrine/metabolic Both 1.02 0.997 1.04 0.0997 10696 106959 FALSE 1.00130484168834 0.0167 0.0102 0.045 0.0287 0.117 1.05 0.989 1.11 0.0206 0.0289 0.475 1.02 0.965 1.08 0.0275 0.0289 0.342 1.03 0.971 1.09 ukb-melanoma-gwas-catalog all 278.3 Localized adiposity Endocrine/metabolic Both 1.01 0.807 1.27 0.908 83 830 FALSE 0.0419141514789149 0.0131 0.114 0.428 0.33 0.195 1.53 0.8 3.02 0.535 0.32 0.0944 1.71 0.912 3.29 -0.0881 0.364 0.809 0.916 0.434 1.91 ukb-melanoma-gwas-catalog all 278.4 Abnormal weight gain Endocrine/metabolic Both 0.92 0.712 1.18 0.512 66 660 FALSE 0.290730039024169 -0.0835 0.127 -0.322 0.351 0.359 0.725 0.355 1.45 -0.233 0.345 0.5 0.792 0.394 1.57 -0.324 0.348 0.351 0.723 0.356 1.44 ukb-melanoma-gwas-catalog all 279 Disorders involving the immune mechanism Endocrine/metabolic Both 0.991 0.87 1.13 0.895 252 2520 FALSE 0.048176964684088 -0.00872 0.0662 -0.221 0.19 0.245 0.802 0.549 1.17 -0.0813 0.184 0.658 0.922 0.641 1.32 0.0792 0.18 0.66 1.08 0.758 1.55 ukb-melanoma-gwas-catalog all 279.1 Immunity deficiency Endocrine/metabolic Both 0.998 0.866 1.15 0.983 211 2110 FALSE 0.00744648216786438 -0.00154 0.0722 -0.395 0.212 0.0624 0.673 0.44 1.02 -0.135 0.198 0.497 0.874 0.59 1.29 0.0678 0.193 0.725 1.07 0.731 1.57 ukb-melanoma-gwas-catalog all 279.11 Deficiency of humoral immunity Endocrine/metabolic Both 0.959 0.805 1.14 0.64 140 1400 FALSE 0.193820026016113 -0.0414 0.0885 -0.318 0.251 0.205 0.728 0.439 1.19 -0.184 0.244 0.451 0.832 0.511 1.35 -0.0568 0.238 0.812 0.945 0.588 1.51 ukb-melanoma-gwas-catalog all 280 Iron deficiency anemias Hematopoietic Both 1.03 1 1.05 0.0269 7750 77478 TRUE 1.57024771999759 0.0264 0.0119 0.0156 0.0341 0.647 1.02 0.95 1.09 0.0579 0.0338 0.0871 1.06 0.992 1.13 0.0577 0.0339 0.089 1.06 0.991 1.13 ukb-melanoma-gwas-catalog all 280.1 Iron deficiency anemias, unspecified or not due to blood loss Hematopoietic Both 1.02 0.999 1.05 0.0569 7378 73758 FALSE 1.24488773360493 0.0233 0.0122 0.0217 0.0349 0.535 1.02 0.954 1.09 0.0614 0.0347 0.0767 1.06 0.993 1.14 0.0498 0.0348 0.153 1.05 0.982 1.13 ukb-melanoma-gwas-catalog all 280.2 Iron deficiency anemia secondary to blood loss (chronic) Hematopoietic Both 1.13 1.03 1.25 0.0108 455 4550 TRUE 1.96657624451305 0.125 0.0488 0.0726 0.145 0.615 1.08 0.809 1.43 0.0747 0.144 0.605 1.08 0.811 1.43 0.333 0.138 0.0155 1.39 1.07 1.83 ukb-melanoma-gwas-catalog all 281 Other deficiency anemia Hematopoietic Both 1.04 0.977 1.1 0.222 1131 11310 FALSE 0.653647025549361 0.0382 0.0313 0.105 0.0886 0.235 1.11 0.934 1.32 0.0563 0.0898 0.531 1.06 0.887 1.26 0.0932 0.0893 0.297 1.1 0.921 1.31 ukb-melanoma-gwas-catalog all 281.1 Megaloblastic anemia Hematopoietic Both 1.05 0.986 1.12 0.125 1074 10740 FALSE 0.903089986991944 0.0492 0.0321 0.13 0.0912 0.153 1.14 0.953 1.36 0.0699 0.0926 0.451 1.07 0.894 1.29 0.122 0.0919 0.186 1.13 0.943 1.35 ukb-melanoma-gwas-catalog all 281.9 Deficiency anemias Hematopoietic Both 0.864 0.653 1.14 0.295 54 540 FALSE 0.530177984021837 -0.146 0.14 -0.104 0.363 0.774 0.901 0.435 1.86 -0.501 0.403 0.214 0.606 0.261 1.34 -0.354 0.389 0.363 0.702 0.314 1.52 ukb-melanoma-gwas-catalog all 281.11 Pernicious anemia Hematopoietic Both 1.05 0.978 1.14 0.168 752 7520 FALSE 0.774690718274137 0.0527 0.0383 0.127 0.109 0.244 1.14 0.917 1.41 0.0815 0.111 0.462 1.08 0.873 1.35 0.14 0.109 0.201 1.15 0.928 1.43 ukb-melanoma-gwas-catalog all 281.12 Other vitamin B12 deficiency anemia Hematopoietic Both 1.09 0.937 1.28 0.253 178 1780 FALSE 0.596879478824182 0.0899 0.0787 0.0075 0.23 0.974 1.01 0.637 1.59 0.251 0.219 0.252 1.29 0.835 1.99 0.155 0.224 0.491 1.17 0.749 1.82 ukb-melanoma-gwas-catalog all 281.13 Folate-deficiency anemia Hematopoietic Both 0.99 0.85 1.15 0.892 186 1860 FALSE 0.0496351456238769 -0.0105 0.0768 0.0171 0.205 0.934 1.02 0.678 1.53 -0.352 0.223 0.114 0.703 0.45 1.09 -0.17 0.214 0.425 0.843 0.551 1.29 ukb-melanoma-gwas-catalog all 282 Hereditary hemolytic anemias Hematopoietic Both 1.03 0.871 1.21 0.748 157 1570 FALSE 0.126098402135539 0.0268 0.0832 -0.102 0.248 0.681 0.903 0.551 1.48 0.315 0.227 0.165 1.37 0.877 2.16 -0.0072 0.243 0.976 0.993 0.612 1.61 ukb-melanoma-gwas-catalog all 282.8 Other hemoglobinopathies Hematopoietic Both 0.916 0.695 1.21 0.525 56 560 FALSE 0.279840696594043 -0.0876 0.138 0.406 0.415 0.328 1.5 0.654 3.56 0.715 0.388 0.0652 2.04 0.96 4.61 -0.102 0.444 0.819 0.903 0.361 2.25 ukb-melanoma-gwas-catalog all 282.9 Other hereditary hemolytic anemias Hematopoietic Both 1.1 0.883 1.38 0.376 85 850 FALSE 0.424812155072339 0.099 0.112 -0.266 0.328 0.417 0.766 0.393 1.47 -0.0291 0.312 0.926 0.971 0.52 1.81 0.137 0.306 0.655 1.15 0.624 2.12 ukb-melanoma-gwas-catalog all 283 Acquired hemolytic anemias Hematopoietic Both 0.985 0.828 1.17 0.859 143 1430 FALSE 0.0660068361687577 -0.0155 0.0873 0.119 0.247 0.63 1.13 0.69 1.85 0.226 0.243 0.352 1.25 0.776 2.04 -0.0187 0.258 0.942 0.981 0.587 1.64 ukb-melanoma-gwas-catalog all 283.1 Autoimmune hemolytic anemias Hematopoietic Both 1 0.823 1.22 0.97 107 1070 FALSE 0.0132282657337552 0.00383 0.1 0.197 0.28 0.483 1.22 0.699 2.14 0.11 0.282 0.696 1.12 0.638 1.96 -0.0427 0.295 0.885 0.958 0.53 1.73 ukb-melanoma-gwas-catalog all 284 Aplastic anemia Hematopoietic Both 1.07 0.969 1.18 0.178 440 4400 FALSE 0.749579997691106 0.0671 0.0499 0.124 0.143 0.388 1.13 0.854 1.5 0.103 0.144 0.474 1.11 0.836 1.47 0.158 0.143 0.269 1.17 0.885 1.55 ukb-melanoma-gwas-catalog all 285 Other anemias Hematopoietic Both 1.02 1 1.04 0.0186 12138 121369 TRUE 1.73048705578208 0.0225 0.00955 -0.00252 0.0272 0.926 0.997 0.946 1.05 0.0239 0.0271 0.377 1.02 0.971 1.08 0.0543 0.027 0.044 1.06 1 1.11 ukb-melanoma-gwas-catalog all 285.1 Acute posthemorrhagic anemia Hematopoietic Both 0.885 0.78 1 0.0569 269 2690 FALSE 1.24488773360493 -0.122 0.064 -0.239 0.177 0.177 0.787 0.554 1.11 -0.208 0.176 0.237 0.812 0.573 1.15 -0.241 0.177 0.172 0.786 0.553 1.11 ukb-melanoma-gwas-catalog all 285.2 Anemia of chronic disease Hematopoietic Both 1.03 0.954 1.12 0.434 693 6930 FALSE 0.362510270487489 0.0312 0.0399 0.0316 0.113 0.78 1.03 0.826 1.29 -0.00495 0.114 0.965 0.995 0.795 1.25 0.0718 0.113 0.526 1.07 0.86 1.34 ukb-melanoma-gwas-catalog all 285.22 Anemia in neoplastic disease Hematopoietic Both 1.07 0.967 1.18 0.189 412 4120 FALSE 0.723538195826756 0.0679 0.0517 0.111 0.147 0.45 1.12 0.837 1.49 -0.0689 0.153 0.653 0.933 0.69 1.26 0.218 0.145 0.135 1.24 0.935 1.66 ukb-melanoma-gwas-catalog all 286 Coagulation defects Hematopoietic Both 1.05 0.983 1.12 0.146 929 9290 FALSE 0.835647144215563 0.05 0.0344 0.0381 0.0989 0.7 1.04 0.855 1.26 0.0932 0.0977 0.34 1.1 0.906 1.33 0.0778 0.098 0.428 1.08 0.892 1.31 ukb-melanoma-gwas-catalog all 286.1 Congenital coagulation defects Hematopoietic Both 1.04 0.945 1.15 0.421 460 4600 FALSE 0.375717904164332 0.0394 0.0489 -0.00946 0.142 0.947 0.991 0.749 1.31 0.201 0.136 0.139 1.22 0.937 1.6 -0.00295 0.142 0.983 0.997 0.754 1.32 ukb-melanoma-gwas-catalog all 286.5 Hemorrhagic disorder due to intrinsic circulating anticoagulants Hematopoietic Both 1.06 0.852 1.33 0.575 85 850 FALSE 0.24033215531037 0.0628 0.112 -0.115 0.331 0.728 0.891 0.456 1.73 0.0809 0.31 0.794 1.08 0.585 2.02 0.119 0.311 0.703 1.13 0.606 2.1 ukb-melanoma-gwas-catalog all 286.7 Other and unspecified coagulation defects Hematopoietic Both 1.08 0.977 1.2 0.125 387 3870 FALSE 0.903089986991944 0.0815 0.0532 0.0798 0.152 0.599 1.08 0.803 1.46 0.0279 0.153 0.856 1.03 0.76 1.39 0.141 0.15 0.348 1.15 0.857 1.55 ukb-melanoma-gwas-catalog all 286.11 Von willebrand's disease Hematopoietic Both 1.05 0.85 1.3 0.646 96 960 FALSE 0.189767482004916 0.0488 0.106 0.377 0.31 0.225 1.46 0.788 2.75 0.465 0.307 0.13 1.59 0.872 2.98 0.243 0.322 0.45 1.28 0.671 2.46 ukb-melanoma-gwas-catalog all 286.12 Congenital deficiency of other clotting factors (including factor VII) Hematopoietic Both 1.04 0.921 1.17 0.536 294 2940 FALSE 0.27083521030723 0.0379 0.0611 -0.0631 0.177 0.721 0.939 0.662 1.33 0.132 0.169 0.436 1.14 0.818 1.59 -0.0146 0.174 0.933 0.986 0.699 1.39 ukb-melanoma-gwas-catalog all 286.13 Congenital factor VIII disorder Hematopoietic Both 1.18 0.911 1.52 0.203 63 630 FALSE 0.692503962086787 0.165 0.129 -0.08 0.385 0.835 0.923 0.421 2.01 0.394 0.356 0.268 1.48 0.734 3.07 0.0736 0.371 0.843 1.08 0.51 2.29 ukb-melanoma-gwas-catalog all 287 Purpura and other hemorrhagic conditions Hematopoietic Both 1.01 0.957 1.06 0.798 1684 16840 FALSE 0.0979971086492705 0.00656 0.0256 -0.0766 0.073 0.294 0.926 0.803 1.07 0.00136 0.0717 0.985 1 0.87 1.15 -0.00683 0.0722 0.925 0.993 0.862 1.14 ukb-melanoma-gwas-catalog all 287.2 Allergic purpura Hematopoietic Both 0.85 0.634 1.13 0.261 51 510 FALSE 0.583359492661719 -0.163 0.145 -0.435 0.387 0.261 0.647 0.293 1.39 -0.0243 0.362 0.947 0.976 0.472 2.01 -1.03 0.468 0.0277 0.357 0.128 0.885 ukb-melanoma-gwas-catalog all 287.3 Thrombocytopenia Hematopoietic Both 1.02 0.963 1.07 0.574 1566 15660 FALSE 0.241088107602026 0.0149 0.0266 -0.0682 0.076 0.37 0.934 0.805 1.08 0.0213 0.0746 0.776 1.02 0.882 1.18 0.0265 0.0748 0.723 1.03 0.887 1.19 ukb-melanoma-gwas-catalog all 287.31 Primary thrombocytopenia Hematopoietic Both 1.05 0.952 1.16 0.315 421 4210 FALSE 0.501689446210399 0.0514 0.0511 0.169 0.147 0.252 1.18 0.886 1.59 0.138 0.149 0.351 1.15 0.858 1.54 0.224 0.146 0.126 1.25 0.938 1.67 ukb-melanoma-gwas-catalog all 287.32 Secondary thrombocytopenia Hematopoietic Both 1.18 0.929 1.49 0.169 75 750 FALSE 0.772113295386326 0.164 0.119 0.507 0.382 0.185 1.66 0.779 3.69 0.852 0.364 0.0193 2.34 1.16 5.03 0.544 0.384 0.157 1.72 0.805 3.84 ukb-melanoma-gwas-catalog all 288 Diseases of white blood cells Hematopoietic Both 0.99 0.957 1.02 0.55 3795 37950 FALSE 0.259637310505756 -0.0102 0.0171 0.00444 0.0477 0.926 1 0.915 1.1 -0.0493 0.0483 0.308 0.952 0.866 1.05 -0.0359 0.0483 0.457 0.965 0.877 1.06 ukb-melanoma-gwas-catalog all 288.1 Decreased white blood cell count Hematopoietic Both 0.988 0.952 1.02 0.508 3192 31920 FALSE 0.294136287716081 -0.0123 0.0186 -0.0066 0.052 0.899 0.993 0.897 1.1 -0.0398 0.0524 0.448 0.961 0.867 1.07 -0.052 0.0528 0.324 0.949 0.856 1.05 ukb-melanoma-gwas-catalog all 288.3 Eosinophilia Hematopoietic Both 1.08 0.841 1.37 0.556 71 710 FALSE 0.254925208417943 0.0725 0.123 0.233 0.354 0.51 1.26 0.622 2.6 0.233 0.349 0.504 1.26 0.631 2.57 0.0522 0.361 0.885 1.05 0.51 2.19 ukb-melanoma-gwas-catalog all 288.11 Neutropenia Hematopoietic Both 0.988 0.952 1.02 0.508 3192 31920 FALSE 0.294136287716081 -0.0123 0.0186 -0.0066 0.052 0.899 0.993 0.897 1.1 -0.0398 0.0524 0.448 0.961 0.867 1.07 -0.052 0.0528 0.324 0.949 0.856 1.05 ukb-melanoma-gwas-catalog all 289 Other diseases of blood and blood-forming organs Hematopoietic Both 1.03 0.964 1.11 0.343 868 8680 FALSE 0.464705879957229 0.0338 0.0356 -0.121 0.103 0.239 0.886 0.724 1.08 -0.0415 0.101 0.68 0.959 0.787 1.17 0.0655 0.0984 0.506 1.07 0.88 1.3 ukb-melanoma-gwas-catalog all 289.3 Personal history of diseases of blood and blood-forming organs Hematopoietic Both 0.987 0.875 1.11 0.836 291 2910 FALSE 0.0777937225609836 -0.0127 0.0614 -0.192 0.171 0.26 0.825 0.588 1.15 -0.45 0.183 0.0139 0.637 0.442 0.912 0.0468 0.162 0.772 1.05 0.762 1.44 ukb-melanoma-gwas-catalog all 289.9 Abnormality of red blood cells Hematopoietic Both 1.15 0.925 1.43 0.206 90 900 FALSE 0.686132779630847 0.138 0.109 -0.158 0.331 0.632 0.853 0.436 1.65 0.246 0.301 0.415 1.28 0.703 2.35 0.187 0.303 0.538 1.21 0.661 2.22 ukb-melanoma-gwas-catalog all 290 Delirium dementia and amnestic and other cognitive disorders Mental Disorders Both 1.08 1.03 1.13 0.00204 1949 19490 TRUE 2.6903698325741 0.0734 0.0238 0.134 0.0684 0.0505 1.14 1 1.31 0.103 0.069 0.136 1.11 0.968 1.27 0.167 0.0682 0.0145 1.18 1.03 1.35 ukb-melanoma-gwas-catalog all 290.1 Dementias Mental Disorders Both 1.08 1.01 1.15 0.0245 1006 10060 TRUE 1.61083391563547 0.0744 0.0331 0.116 0.0949 0.22 1.12 0.933 1.35 0.101 0.0955 0.291 1.11 0.917 1.33 0.149 0.0948 0.117 1.16 0.963 1.4 ukb-melanoma-gwas-catalog all 290.2 Delirium due to conditions classified elsewhere Mental Disorders Both 1.05 0.972 1.14 0.205 651 6510 FALSE 0.688246138944246 0.0522 0.0412 0.224 0.117 0.055 1.25 0.995 1.58 0.077 0.121 0.525 1.08 0.851 1.37 0.166 0.119 0.161 1.18 0.936 1.49 ukb-melanoma-gwas-catalog all 290.11 Alzheimer's disease Mental Disorders Both 1.1 0.997 1.22 0.0553 433 4330 FALSE 1.2572748686953 0.0962 0.0502 0.153 0.147 0.297 1.17 0.873 1.56 0.183 0.146 0.21 1.2 0.901 1.6 0.265 0.144 0.0668 1.3 0.982 1.73 ukb-melanoma-gwas-catalog all 290.16 Vascular dementia Mental Disorders Both 1.11 0.96 1.28 0.155 201 2010 FALSE 0.809668301829709 0.105 0.0737 0.129 0.211 0.541 1.14 0.75 1.73 0.107 0.212 0.613 1.11 0.732 1.7 0.18 0.211 0.392 1.2 0.79 1.82 ukb-melanoma-gwas-catalog all 291 Other specified nonpsychotic and/or transient mental disorders Mental Disorders Both 1.09 1 1.18 0.0435 638 6380 TRUE 1.36151074304536 0.0839 0.0415 -0.108 0.124 0.383 0.897 0.702 1.15 0.157 0.118 0.183 1.17 0.929 1.47 0.232 0.116 0.0457 1.26 1 1.59 ukb-melanoma-gwas-catalog all 291.1 Transient mental disorders due to conditions classified elsewhere Mental Disorders Both 0.896 0.741 1.08 0.248 121 1210 FALSE 0.605548319173784 -0.11 0.0953 -0.11 0.261 0.673 0.896 0.532 1.5 -0.0871 0.261 0.739 0.917 0.544 1.54 -0.23 0.27 0.395 0.795 0.462 1.36 ukb-melanoma-gwas-catalog all 291.4 Specific nonpsychotic mental disorders due to brain damage Mental Disorders Both 1.13 0.907 1.41 0.261 85 850 FALSE 0.583359492661719 0.125 0.111 -0.34 0.34 0.317 0.712 0.355 1.4 0.24 0.302 0.427 1.27 0.699 2.34 0.0553 0.314 0.861 1.06 0.563 1.99 ukb-melanoma-gwas-catalog all 291.8 Alteration of consciousness Mental Disorders Both 1.13 1.02 1.24 0.0182 437 4370 TRUE 1.73992861201493 0.119 0.0502 -0.0678 0.152 0.655 0.934 0.692 1.26 0.2 0.144 0.163 1.22 0.922 1.62 0.344 0.14 0.0143 1.41 1.07 1.86 ukb-melanoma-gwas-catalog all 292 Neurological disorders Mental Disorders Both 1.03 0.997 1.06 0.0732 4645 46450 FALSE 1.13548891894161 0.0276 0.0154 0.0521 0.0439 0.235 1.05 0.967 1.15 0.0209 0.0442 0.637 1.02 0.936 1.11 0.0894 0.0437 0.0407 1.09 1 1.19 ukb-melanoma-gwas-catalog all 292.1 Aphasia/speech disturbance Mental Disorders Both 1.04 0.987 1.1 0.14 1507 15070 FALSE 0.853871964321762 0.0399 0.0271 0.0719 0.0785 0.359 1.07 0.921 1.25 0.182 0.0768 0.018 1.2 1.03 1.39 0.123 0.078 0.115 1.13 0.971 1.32 ukb-melanoma-gwas-catalog all 292.2 Mild cognitive impairment Mental Disorders Both 0.967 0.832 1.12 0.662 190 1900 FALSE 0.1791420105603 -0.0332 0.0759 -0.0642 0.212 0.762 0.938 0.616 1.42 -0.127 0.213 0.552 0.881 0.576 1.34 -0.0436 0.209 0.835 0.957 0.633 1.45 ukb-melanoma-gwas-catalog all 292.3 Memory loss Mental Disorders Both 1.03 0.953 1.11 0.455 700 7000 FALSE 0.341988603342888 0.0296 0.0397 -0.00269 0.115 0.981 0.997 0.796 1.25 0.0492 0.113 0.665 1.05 0.841 1.31 0.145 0.111 0.192 1.16 0.93 1.44 ukb-melanoma-gwas-catalog all 292.4 Altered mental status Mental Disorders Both 1.01 0.967 1.06 0.622 2185 21850 FALSE 0.206209615309181 0.0111 0.0225 0.0479 0.0628 0.445 1.05 0.928 1.19 -0.0736 0.0646 0.255 0.929 0.818 1.05 0.0226 0.0635 0.722 1.02 0.903 1.16 ukb-melanoma-gwas-catalog all 292.6 Hallucinations Mental Disorders Both 1.1 0.982 1.24 0.0958 308 3080 FALSE 1.01863449092146 0.0993 0.0596 0.364 0.171 0.0332 1.44 1.03 2.02 0.127 0.179 0.477 1.14 0.798 1.62 0.278 0.175 0.112 1.32 0.936 1.87 ukb-melanoma-gwas-catalog all 293 Symptoms involving head and neck Mental Disorders Both 1.02 0.972 1.06 0.46 2082 20820 FALSE 0.337242168318426 0.017 0.0231 -0.0333 0.0657 0.613 0.967 0.85 1.1 -0.00379 0.0654 0.954 0.996 0.876 1.13 0.0616 0.0647 0.341 1.06 0.937 1.21 ukb-melanoma-gwas-catalog all 295 Schizophrenia and other psychotic disorders Mental Disorders Both 1.01 0.942 1.09 0.76 851 8510 FALSE 0.119186407719209 0.011 0.0361 0.0448 0.104 0.667 1.05 0.852 1.28 0.158 0.102 0.121 1.17 0.959 1.43 0.107 0.104 0.301 1.11 0.908 1.37 ukb-melanoma-gwas-catalog all 295.1 Schizophrenia Mental Disorders Both 0.987 0.905 1.08 0.766 572 5720 FALSE 0.115771230367396 -0.0131 0.044 0.0948 0.126 0.453 1.1 0.858 1.41 0.186 0.124 0.133 1.2 0.945 1.54 0.0772 0.128 0.547 1.08 0.839 1.39 ukb-melanoma-gwas-catalog all 295.2 Paranoid disorders Mental Disorders Both 1.1 0.947 1.29 0.204 179 1790 FALSE 0.690369832574101 0.0989 0.0778 0.127 0.231 0.583 1.13 0.719 1.8 0.261 0.224 0.243 1.3 0.835 2.03 0.254 0.224 0.255 1.29 0.831 2.02 ukb-melanoma-gwas-catalog all 295.3 Psychosis Mental Disorders Both 0.933 0.796 1.09 0.393 171 1710 FALSE 0.405607449624573 -0.0689 0.0806 -0.311 0.225 0.167 0.732 0.467 1.14 -0.146 0.217 0.503 0.864 0.561 1.33 -0.232 0.224 0.3 0.793 0.507 1.23 ukb-melanoma-gwas-catalog all 296 Mood disorders Mental Disorders Both 1.01 0.987 1.02 0.531 12461 124609 FALSE 0.274905478918531 0.0059 0.00943 0.00443 0.0266 0.868 1 0.953 1.06 0.00178 0.0266 0.947 1 0.951 1.06 -0.00486 0.0267 0.856 0.995 0.944 1.05 ukb-melanoma-gwas-catalog all 296.1 Bipolar Mental Disorders Both 0.986 0.925 1.05 0.667 1058 10580 FALSE 0.175874166083451 -0.0139 0.0323 -0.0322 0.0908 0.723 0.968 0.81 1.16 -0.077 0.0919 0.402 0.926 0.773 1.11 0.00434 0.0904 0.962 1 0.841 1.2 ukb-melanoma-gwas-catalog all 296.2 Depression Mental Disorders Both 1.01 0.987 1.02 0.572 11805 118049 FALSE 0.242603971206976 0.00547 0.00969 0.00399 0.0273 0.884 1 0.952 1.06 0.00564 0.0273 0.837 1.01 0.953 1.06 -0.00847 0.0275 0.758 0.992 0.94 1.05 ukb-melanoma-gwas-catalog all 296.22 Major depressive disorder Mental Disorders Both 1.03 0.922 1.15 0.623 361 3610 FALSE 0.20551195334083 0.0271 0.0552 -0.418 0.167 0.0124 0.658 0.472 0.913 -0.0782 0.153 0.61 0.925 0.683 1.25 0.121 0.147 0.411 1.13 0.845 1.51 ukb-melanoma-gwas-catalog all 297 Suicidal ideation or attempt Mental Disorders Both 0.984 0.88 1.1 0.773 343 3391 FALSE 0.111820506081675 -0.0163 0.0567 -0.328 0.159 0.039 0.721 0.526 0.983 -0.371 0.161 0.0211 0.69 0.501 0.945 -0.0918 0.151 0.544 0.912 0.677 1.23 ukb-melanoma-gwas-catalog all 297.2 Suicide or self-inflicted injury Mental Disorders Both 0.991 0.883 1.11 0.884 319 3161 FALSE 0.0535477349869269 -0.00862 0.0589 -0.31 0.165 0.0602 0.733 0.528 1.01 -0.352 0.167 0.0356 0.704 0.504 0.976 -0.0484 0.157 0.758 0.953 0.699 1.3 ukb-melanoma-gwas-catalog all 300 Anxiety disorders Mental Disorders Both 1.01 0.984 1.03 0.502 6904 69029 FALSE 0.299296282854981 0.00849 0.0127 0.0126 0.0358 0.724 1.01 0.944 1.09 -0.0163 0.0361 0.652 0.984 0.917 1.06 0.0386 0.0357 0.28 1.04 0.969 1.11 ukb-melanoma-gwas-catalog all 300.1 Anxiety disorder Mental Disorders Both 1 0.979 1.03 0.737 6341 63399 FALSE 0.132532512140949 0.00444 0.0132 -0.00725 0.0373 0.846 0.993 0.923 1.07 -0.0383 0.0376 0.308 0.962 0.894 1.04 0.0213 0.0372 0.567 1.02 0.95 1.1 ukb-melanoma-gwas-catalog all 300.3 Obsessive-compulsive disorders Mental Disorders Both 0.94 0.788 1.12 0.483 140 1400 FALSE 0.316052869248488 -0.0622 0.0885 0.406 0.248 0.102 1.5 0.922 2.47 0.174 0.258 0.5 1.19 0.714 2 0.145 0.262 0.58 1.16 0.687 1.96 ukb-melanoma-gwas-catalog all 300.4 Dysthymic disorder Mental Disorders Both 1.2 0.905 1.59 0.198 53 530 FALSE 0.703334809738469 0.181 0.141 0.293 0.44 0.506 1.34 0.552 3.34 0.408 0.428 0.34 1.5 0.636 3.69 0.695 0.411 0.091 2 0.893 4.78 ukb-melanoma-gwas-catalog all 300.8 Acute reaction to stress Mental Disorders Both 1.3 1.08 1.56 0.0044 125 1250 TRUE 2.35654732351381 0.261 0.0916 0.241 0.292 0.41 1.27 0.711 2.3 0.504 0.282 0.0744 1.65 0.951 2.94 0.664 0.273 0.0152 1.94 1.14 3.4 ukb-melanoma-gwas-catalog all 300.9 Posttraumatic stress disorder Mental Disorders Both 1.05 0.866 1.28 0.61 113 1130 FALSE 0.214670164989233 0.05 0.0981 0.16 0.292 0.585 1.17 0.656 2.11 0.406 0.275 0.14 1.5 0.875 2.62 0.0864 0.293 0.768 1.09 0.609 1.96 ukb-melanoma-gwas-catalog all 300.11 Generalized anxiety disorder Mental Disorders Both 0.914 0.772 1.08 0.292 150 1500 FALSE 0.534617148551582 -0.0899 0.0854 -0.434 0.24 0.07 0.648 0.4 1.04 -0.403 0.237 0.0897 0.668 0.415 1.06 -0.161 0.225 0.474 0.851 0.544 1.33 ukb-melanoma-gwas-catalog all 300.12 Agorophobia, social phobia, and panic disorder Mental Disorders Both 0.995 0.92 1.08 0.894 704 7040 FALSE 0.0486624812040823 -0.0053 0.0396 -0.127 0.111 0.254 0.881 0.707 1.1 -0.152 0.112 0.175 0.859 0.689 1.07 0.00278 0.109 0.98 1 0.809 1.24 ukb-melanoma-gwas-catalog all 300.13 Phobia Mental Disorders Both 0.984 0.897 1.08 0.73 497 4970 FALSE 0.136677139879544 -0.0163 0.0472 0.0235 0.132 0.858 1.02 0.79 1.33 0.0491 0.131 0.709 1.05 0.811 1.36 -0.084 0.136 0.536 0.919 0.703 1.2 ukb-melanoma-gwas-catalog all 301 Personality disorders Mental Disorders Both 1.09 0.976 1.22 0.121 337 3366 FALSE 0.91721462968355 0.0884 0.057 -0.339 0.17 0.0456 0.712 0.508 0.993 -0.2 0.163 0.219 0.818 0.592 1.13 0.211 0.151 0.163 1.23 0.918 1.66 ukb-melanoma-gwas-catalog all 301.2 Antisocial/borderline personality disorder Mental Disorders Both 1.05 0.866 1.26 0.633 119 1186 FALSE 0.198596289982645 0.0456 0.0956 -0.428 0.282 0.13 0.652 0.368 1.14 -0.225 0.264 0.395 0.799 0.47 1.35 0.0792 0.255 0.756 1.08 0.653 1.8 ukb-melanoma-gwas-catalog all 302 Sexual and gender identity disorders Mental Disorders Both 1.07 0.956 1.2 0.232 322 3220 FALSE 0.6345120151091 0.0694 0.0581 0.118 0.169 0.484 1.13 0.807 1.57 0.2 0.167 0.23 1.22 0.88 1.7 0.179 0.167 0.285 1.2 0.861 1.67 ukb-melanoma-gwas-catalog all 303 Psychogenic and somatoform disorders Mental Disorders Both 1.08 0.983 1.18 0.107 489 4890 FALSE 0.97061622231479 0.0764 0.0474 0.184 0.133 0.165 1.2 0.927 1.56 -0.0627 0.14 0.655 0.939 0.712 1.24 0.144 0.134 0.285 1.15 0.887 1.51 ukb-melanoma-gwas-catalog all 303.3 Psychogenic disorder Mental Disorders Both 1.04 0.931 1.16 0.49 354 3540 FALSE 0.309803919971486 0.0385 0.0557 0.201 0.154 0.193 1.22 0.903 1.66 -0.0333 0.163 0.838 0.967 0.702 1.33 0.0592 0.16 0.712 1.06 0.774 1.46 ukb-melanoma-gwas-catalog all 303.4 Somatoform disorder Mental Disorders Both 1.23 1.02 1.48 0.0271 124 1240 TRUE 1.56703070912559 0.206 0.0931 0.119 0.268 0.657 1.13 0.661 1.93 -0.121 0.283 0.669 0.886 0.501 1.56 0.399 0.256 0.119 1.49 0.902 2.49 ukb-melanoma-gwas-catalog all 304 Adjustment reaction Mental Disorders Both 0.991 0.878 1.12 0.881 295 2950 FALSE 0.0550240915879521 -0.00914 0.0611 0.0565 0.168 0.737 1.06 0.759 1.48 -0.0412 0.173 0.811 0.96 0.682 1.35 -0.0752 0.174 0.665 0.928 0.658 1.31 ukb-melanoma-gwas-catalog all 306 Other mental disorder Mental Disorders Both 1.01 0.997 1.02 0.156 28125 230574 FALSE 0.806875401645538 0.00903 0.00635 0.0308 0.018 0.0874 1.03 0.996 1.07 0.0308 0.018 0.0868 1.03 0.996 1.07 0.0266 0.0181 0.141 1.03 0.991 1.06 ukb-melanoma-gwas-catalog all 306.9 Tension headache Mental Disorders Both 1.05 0.939 1.18 0.366 315 3150 FALSE 0.436518914605589 0.0532 0.0588 0.135 0.174 0.438 1.14 0.812 1.62 0.293 0.17 0.0841 1.34 0.961 1.88 0.253 0.17 0.137 1.29 0.922 1.81 ukb-melanoma-gwas-catalog all 313 Pervasive developmental disorders Mental Disorders Both 0.874 0.69 1.11 0.258 77 770 FALSE 0.58838029403677 -0.134 0.119 -0.441 0.337 0.19 0.643 0.323 1.25 -0.0297 0.306 0.923 0.971 0.527 1.78 -0.434 0.337 0.198 0.648 0.324 1.26 ukb-melanoma-gwas-catalog all 313.3 Autism Mental Disorders Both 0.853 0.641 1.13 0.264 54 540 FALSE 0.578396073130169 -0.159 0.142 -0.692 0.421 0.1 0.501 0.205 1.14 -0.033 0.353 0.925 0.968 0.477 1.96 -0.442 0.388 0.255 0.643 0.288 1.38 ukb-melanoma-gwas-catalog all 315 Develomental delays and disorders Mental Disorders Both 0.894 0.801 0.999 0.0466 353 3530 TRUE 1.33161408331 -0.112 0.0561 -0.0987 0.151 0.514 0.906 0.672 1.22 -0.143 0.153 0.35 0.867 0.64 1.17 -0.33 0.161 0.0398 0.719 0.522 0.985 ukb-melanoma-gwas-catalog all 315.2 Speech and language disorder Mental Disorders Both 0.913 0.73 1.14 0.419 89 890 FALSE 0.377785977033705 -0.0905 0.112 0.258 0.299 0.388 1.29 0.717 2.37 0.0969 0.314 0.758 1.1 0.589 2.07 -0.316 0.34 0.352 0.729 0.365 1.43 ukb-melanoma-gwas-catalog all 316 Substance addiction and disorders Mental Disorders Both 1.01 0.91 1.12 0.861 395 3950 FALSE 0.0649968485463452 0.00924 0.0528 -0.00708 0.148 0.962 0.993 0.741 1.33 0.0358 0.148 0.808 1.04 0.775 1.39 -0.029 0.15 0.847 0.971 0.722 1.31 ukb-melanoma-gwas-catalog all 316.1 Polyneuropathy due to drugs Mental Disorders Both 1.38 1.06 1.79 0.0147 60 600 TRUE 1.83268266525182 0.321 0.131 0.191 0.414 0.645 1.21 0.52 2.85 0.353 0.391 0.366 1.42 0.652 3.21 0.633 0.379 0.0944 1.88 0.898 4.15 ukb-melanoma-gwas-catalog all 317 Alcohol-related disorders Mental Disorders Both 1.03 1.01 1.05 0.00351 12829 128124 TRUE 2.45469288353418 0.0271 0.00929 0.0426 0.0264 0.107 1.04 0.991 1.1 0.0431 0.0264 0.103 1.04 0.991 1.1 0.0591 0.0264 0.0254 1.06 1.01 1.12 ukb-melanoma-gwas-catalog all 317.1 Alcoholism Mental Disorders Both 1.02 0.999 1.04 0.0576 8924 89210 FALSE 1.23957751657679 0.0211 0.0111 0.0385 0.0317 0.224 1.04 0.977 1.11 0.0455 0.0316 0.151 1.05 0.984 1.11 0.0497 0.0317 0.117 1.05 0.988 1.12 ukb-melanoma-gwas-catalog all 317.11 Alcoholic liver damage Mental Disorders Both 1.1 1.02 1.18 0.0089 842 8420 TRUE 2.05060999335509 0.0944 0.0361 0.0752 0.105 0.473 1.08 0.878 1.32 0.00658 0.106 0.951 1.01 0.817 1.24 0.267 0.101 0.00844 1.31 1.07 1.6 ukb-melanoma-gwas-catalog all 318 Tobacco use disorder Mental Disorders Both 1.02 1 1.03 0.04 19447 185990 TRUE 1.39794000867204 0.0155 0.00757 0.0371 0.0215 0.084 1.04 0.995 1.08 0.0331 0.0215 0.124 1.03 0.991 1.08 0.0432 0.0215 0.0449 1.04 1 1.09 ukb-melanoma-gwas-catalog all 320 Meningitis Neurological Both 0.982 0.891 1.08 0.72 448 4480 FALSE 0.142667503568732 -0.0178 0.0496 -0.194 0.139 0.164 0.824 0.626 1.08 -0.18 0.139 0.197 0.835 0.634 1.1 -0.051 0.136 0.707 0.95 0.727 1.24 ukb-melanoma-gwas-catalog all 323 Encephalitis Neurological Both 0.946 0.847 1.06 0.328 353 3530 FALSE 0.484126156288321 -0.0552 0.0564 0.0349 0.154 0.821 1.04 0.764 1.4 -0.0403 0.157 0.797 0.96 0.705 1.31 -0.145 0.161 0.367 0.865 0.629 1.19 ukb-melanoma-gwas-catalog all 323.2 Acute (transverse) myelitis Neurological Both 0.816 0.635 1.04 0.103 74 740 FALSE 0.987162775294828 -0.204 0.125 -0.117 0.316 0.711 0.89 0.472 1.66 -0.382 0.337 0.258 0.682 0.342 1.33 -0.355 0.342 0.298 0.701 0.349 1.38 ukb-melanoma-gwas-catalog all 324 Other CNS infection and poliomyelitis Neurological Both 1.16 1.03 1.31 0.0143 295 2950 TRUE 1.84466396253494 0.149 0.0609 0.276 0.18 0.126 1.32 0.925 1.89 0.289 0.179 0.106 1.34 0.94 1.91 0.292 0.18 0.104 1.34 0.941 1.92 ukb-melanoma-gwas-catalog all 327 Sleep disorders Neurological Both 0.989 0.931 1.05 0.722 1170 11700 FALSE 0.141462802430361 -0.011 0.0308 0.12 0.0851 0.158 1.13 0.954 1.33 -0.0487 0.0882 0.581 0.953 0.801 1.13 -0.0173 0.0884 0.845 0.983 0.826 1.17 ukb-melanoma-gwas-catalog all 327.3 Sleep apnea Neurological Both 0.998 0.901 1.11 0.974 404 4040 FALSE 0.0114410431213845 -0.00172 0.0523 0.103 0.143 0.473 1.11 0.836 1.47 -0.166 0.152 0.276 0.847 0.626 1.14 0.0165 0.147 0.911 1.02 0.761 1.36 ukb-melanoma-gwas-catalog all 327.4 Insomnia Neurological Both 0.978 0.832 1.15 0.787 165 1650 FALSE 0.104025267640935 -0.0221 0.0815 0.372 0.23 0.106 1.45 0.924 2.3 0.265 0.234 0.257 1.3 0.822 2.08 0.0355 0.249 0.886 1.04 0.631 1.7 ukb-melanoma-gwas-catalog all 327.41 Organic or persistent insomnia Neurological Both 0.944 0.79 1.12 0.515 138 1380 FALSE 0.288192770958809 -0.0581 0.0893 0.459 0.245 0.0607 1.58 0.98 2.59 0.198 0.257 0.442 1.22 0.732 2.04 -0.0914 0.276 0.74 0.913 0.524 1.58 ukb-melanoma-gwas-catalog all 331 Other cerebral degenerations Neurological Both 0.953 0.897 1.01 0.124 1146 11460 FALSE 0.906578314837765 -0.0478 0.0311 -0.116 0.086 0.179 0.891 0.752 1.05 -0.118 0.0863 0.171 0.889 0.75 1.05 -0.167 0.0877 0.0575 0.847 0.712 1.01 ukb-melanoma-gwas-catalog all 331.1 Hydrocephalus Neurological Both 0.962 0.877 1.06 0.413 502 5020 FALSE 0.384049948343599 -0.0385 0.047 -0.208 0.131 0.114 0.812 0.627 1.05 -0.131 0.129 0.31 0.877 0.68 1.13 -0.159 0.131 0.225 0.853 0.659 1.1 ukb-melanoma-gwas-catalog all 331.9 Cerebral degeneration, unspecified Neurological Both 0.932 0.843 1.03 0.165 429 4290 FALSE 0.782516055786094 -0.0704 0.0508 -0.0465 0.138 0.737 0.955 0.727 1.25 -0.158 0.143 0.268 0.854 0.644 1.13 -0.167 0.143 0.244 0.846 0.638 1.12 ukb-melanoma-gwas-catalog all 332 Parkinson's disease Neurological Both 1.03 0.967 1.09 0.377 1128 11280 FALSE 0.423658649794207 0.0276 0.0313 0.17 0.0884 0.0545 1.19 0.997 1.41 0.0516 0.091 0.571 1.05 0.881 1.26 0.116 0.0897 0.195 1.12 0.942 1.34 ukb-melanoma-gwas-catalog all 333 Extrapyramidal disease and abnormal movement disorders Neurological Both 0.987 0.922 1.06 0.713 901 9010 FALSE 0.146910470148134 -0.0129 0.035 -0.00995 0.0982 0.919 0.99 0.816 1.2 0.0195 0.0975 0.842 1.02 0.842 1.24 -0.084 0.1 0.401 0.919 0.755 1.12 ukb-melanoma-gwas-catalog all 333.1 Essential tremor Neurological Both 0.971 0.844 1.12 0.677 216 2160 FALSE 0.169411331314856 -0.0295 0.071 -0.109 0.203 0.592 0.897 0.599 1.34 0.0769 0.194 0.692 1.08 0.736 1.59 -0.0527 0.201 0.793 0.949 0.637 1.41 ukb-melanoma-gwas-catalog all 333.2 Myoclonus Neurological Both 0.915 0.739 1.13 0.406 96 960 FALSE 0.391473966422806 -0.0889 0.107 0.233 0.275 0.397 1.26 0.733 2.19 -0.452 0.323 0.162 0.636 0.327 1.2 -0.189 0.305 0.535 0.828 0.448 1.52 ukb-melanoma-gwas-catalog all 333.4 Torsion dystonia Neurological Both 0.953 0.837 1.08 0.461 253 2530 FALSE 0.336299074610352 -0.0485 0.0659 -0.119 0.19 0.531 0.888 0.608 1.29 0.259 0.176 0.142 1.3 0.917 1.84 -0.195 0.194 0.316 0.823 0.56 1.21 ukb-melanoma-gwas-catalog all 334 Degenerative disease of the spinal cord Neurological Both 1.02 0.972 1.07 0.422 1818 18180 FALSE 0.374687549038326 0.0198 0.0246 -0.0451 0.0707 0.524 0.956 0.832 1.1 0.0821 0.069 0.234 1.09 0.948 1.24 0.0251 0.0699 0.72 1.03 0.894 1.18 ukb-melanoma-gwas-catalog all 334.1 Spinocerebellar disease Neurological Both 0.892 0.738 1.08 0.232 117 1170 FALSE 0.6345120151091 -0.115 0.0959 -0.374 0.269 0.164 0.688 0.399 1.17 -0.186 0.258 0.471 0.83 0.496 1.38 -0.408 0.27 0.13 0.665 0.386 1.13 ukb-melanoma-gwas-catalog all 334.2 Anterior horn cell disease Neurological Both 0.989 0.867 1.13 0.869 245 2450 FALSE 0.0609802235513335 -0.011 0.0667 0.0368 0.194 0.85 1.04 0.707 1.52 0.289 0.184 0.117 1.34 0.93 1.93 -0.0317 0.196 0.872 0.969 0.656 1.43 ukb-melanoma-gwas-catalog all 335 Multiple sclerosis Neurological Both 0.985 0.931 1.04 0.594 1354 13540 FALSE 0.226213555018806 -0.0152 0.0286 0.0134 0.0805 0.868 1.01 0.865 1.19 0.0425 0.0802 0.596 1.04 0.892 1.22 -0.0356 0.0819 0.663 0.965 0.822 1.13 ukb-melanoma-gwas-catalog all 337 Disorders of the autonomic nervous system Neurological Both 1.12 0.99 1.27 0.07 269 2690 FALSE 1.15490195998574 0.116 0.0638 -0.133 0.186 0.476 0.876 0.605 1.26 -0.0124 0.182 0.946 0.988 0.689 1.42 0.193 0.175 0.269 1.21 0.86 1.72 ukb-melanoma-gwas-catalog all 337.1 Peripheral autonomic neuropathy Neurological Both 1.12 0.878 1.42 0.359 72 720 FALSE 0.444905551421681 0.111 0.121 0.109 0.354 0.759 1.11 0.547 2.29 0.33 0.346 0.341 1.39 0.699 2.82 0.25 0.349 0.474 1.28 0.64 2.62 ukb-melanoma-gwas-catalog all 338 Pain Neurological Both 0.976 0.906 1.05 0.52 772 7720 FALSE 0.283996656365201 -0.0244 0.0379 -0.0769 0.107 0.471 0.926 0.751 1.14 -0.032 0.106 0.762 0.968 0.786 1.19 -0.0304 0.106 0.775 0.97 0.787 1.19 ukb-melanoma-gwas-catalog all 338.1 Acute pain Neurological Both 0.916 0.825 1.02 0.096 395 3950 FALSE 1.01772876696043 -0.0882 0.053 0.148 0.144 0.302 1.16 0.874 1.54 -0.0458 0.151 0.762 0.955 0.709 1.29 -0.118 0.153 0.44 0.888 0.657 1.2 ukb-melanoma-gwas-catalog all 338.2 Chronic pain Neurological Both 1.02 0.917 1.13 0.722 383 3830 FALSE 0.141462802430361 0.0191 0.0537 -0.337 0.158 0.0323 0.714 0.522 0.972 -0.0285 0.146 0.846 0.972 0.728 1.3 -0.00111 0.146 0.994 0.999 0.749 1.33 ukb-melanoma-gwas-catalog all 339 Other headache syndromes Neurological Both 1.02 0.996 1.04 0.103 7843 78413 FALSE 0.987162775294828 0.0194 0.0119 -0.00763 0.0337 0.821 0.992 0.929 1.06 0.0102 0.0337 0.762 1.01 0.946 1.08 0.0423 0.0335 0.208 1.04 0.977 1.11 ukb-melanoma-gwas-catalog all 340 Migraine Neurological Both 1.05 1.01 1.09 0.0235 2867 28670 TRUE 1.62893213772826 0.0444 0.0196 -0.0411 0.0562 0.465 0.96 0.859 1.07 0.00836 0.0556 0.881 1.01 0.904 1.12 0.0741 0.055 0.177 1.08 0.967 1.2 ukb-melanoma-gwas-catalog all 340.1 Migrain with aura Neurological Both 1.01 0.879 1.17 0.851 212 2120 FALSE 0.0700704399154121 0.0135 0.0719 -0.12 0.204 0.556 0.887 0.592 1.33 0.00494 0.198 0.98 1 0.679 1.49 -0.0656 0.202 0.746 0.936 0.627 1.4 ukb-melanoma-gwas-catalog all 341 Other demyelinating diseases of central nervous system Neurological Both 0.99 0.87 1.13 0.874 254 2540 FALSE 0.058488567365597 -0.0104 0.0655 -0.104 0.186 0.578 0.901 0.623 1.3 0.0809 0.179 0.652 1.08 0.762 1.55 -0.0879 0.187 0.638 0.916 0.632 1.32 ukb-melanoma-gwas-catalog all 342 Hemiplegia Neurological Both 0.98 0.929 1.03 0.465 1498 14980 FALSE 0.332547047110046 -0.0199 0.0272 -0.0979 0.0761 0.198 0.907 0.781 1.05 -0.105 0.0763 0.167 0.9 0.775 1.05 -0.0788 0.076 0.3 0.924 0.796 1.07 ukb-melanoma-gwas-catalog all 343 Infantile cerebral palsy Neurological Both 0.93 0.782 1.1 0.408 145 1450 FALSE 0.38933983691012 -0.0724 0.0874 -0.0123 0.243 0.96 0.988 0.609 1.6 0.0156 0.244 0.949 1.02 0.626 1.65 0.0167 0.246 0.946 1.02 0.623 1.66 ukb-melanoma-gwas-catalog all 344 Other paralytic syndromes Neurological Both 1.06 0.978 1.15 0.155 661 6610 FALSE 0.809668301829709 0.0579 0.0408 0.199 0.116 0.0867 1.22 0.972 1.54 0.105 0.119 0.374 1.11 0.88 1.4 0.148 0.117 0.206 1.16 0.921 1.46 ukb-melanoma-gwas-catalog all 345 Epilepsy, recurrent seizures, convulsions Neurological Both 1.01 0.986 1.04 0.316 5083 50830 FALSE 0.500312917381596 0.0148 0.0148 0.109 0.042 0.0098 1.11 1.03 1.21 0.119 0.042 0.00462 1.13 1.04 1.22 0.072 0.0427 0.0915 1.07 0.988 1.17 ukb-melanoma-gwas-catalog all 345.1 Epilepsy Neurological Both 1.04 0.974 1.12 0.225 898 8980 FALSE 0.647817481888638 0.0425 0.035 -0.0494 0.101 0.625 0.952 0.78 1.16 0.0924 0.0981 0.346 1.1 0.905 1.33 0.0423 0.0995 0.671 1.04 0.858 1.27 ukb-melanoma-gwas-catalog all 345.3 Convulsions Neurological Both 1 0.961 1.05 0.877 2235 22350 FALSE 0.0570004066339595 0.00343 0.0223 0.0404 0.0627 0.519 1.04 0.921 1.18 0.0263 0.063 0.676 1.03 0.907 1.16 0.021 0.0635 0.741 1.02 0.902 1.16 ukb-melanoma-gwas-catalog all 345.11 Generalized convulsive epilepsy Neurological Both 1.07 0.973 1.18 0.159 445 4450 FALSE 0.798602875679548 0.07 0.0497 -0.0299 0.145 0.837 0.971 0.729 1.29 0.16 0.14 0.252 1.17 0.892 1.55 0.103 0.142 0.466 1.11 0.839 1.47 ukb-melanoma-gwas-catalog all 345.12 Partial epilepsy Neurological Both 1.08 0.954 1.22 0.223 279 2790 FALSE 0.651695136951839 0.0762 0.0625 -0.101 0.182 0.58 0.904 0.63 1.3 0.046 0.176 0.794 1.05 0.74 1.48 0.0945 0.175 0.589 1.1 0.779 1.55 ukb-melanoma-gwas-catalog all 348 Other conditions of brain Neurological Both 1.04 0.964 1.12 0.329 791 7910 FALSE 0.482804102050026 0.0364 0.0373 0.0232 0.109 0.831 1.02 0.827 1.27 0.229 0.104 0.028 1.26 1.03 1.54 0.0693 0.108 0.522 1.07 0.866 1.33 ukb-melanoma-gwas-catalog all 348.2 Cerebral edema and compression of brain Neurological Both 1.05 0.927 1.19 0.429 268 2680 FALSE 0.367542707815276 0.0506 0.0639 -0.251 0.195 0.197 0.778 0.528 1.14 0.297 0.173 0.0863 1.35 0.958 1.9 0.0827 0.182 0.649 1.09 0.759 1.56 ukb-melanoma-gwas-catalog all 348.4 Cerebral cysts Neurological Both 1 0.84 1.2 0.975 136 1360 FALSE 0.0109953843014632 0.00278 0.0894 0.202 0.242 0.404 1.22 0.759 1.98 -0.351 0.272 0.197 0.704 0.406 1.2 0.0263 0.248 0.916 1.03 0.627 1.68 ukb-melanoma-gwas-catalog all 348.8 Encephalopathy, not elsewhere classified Neurological Both 1.04 0.912 1.18 0.565 252 2520 FALSE 0.247951552180562 0.0379 0.0659 0.213 0.186 0.253 1.24 0.858 1.79 0.127 0.191 0.506 1.14 0.779 1.66 0.1 0.191 0.6 1.11 0.758 1.62 ukb-melanoma-gwas-catalog all 349 Other and unspecified disorders of the nervous system Neurological Both 0.935 0.836 1.04 0.233 342 3420 FALSE 0.632644078973981 -0.0677 0.0567 -0.128 0.154 0.406 0.879 0.648 1.19 -0.116 0.154 0.452 0.891 0.657 1.21 -0.331 0.163 0.0429 0.718 0.519 0.989 ukb-melanoma-gwas-catalog all 350 Abnormal movement Neurological Both 1.02 0.981 1.06 0.299 2691 26910 FALSE 0.52432881167557 0.0211 0.0203 0.0331 0.0571 0.562 1.03 0.924 1.16 -0.0405 0.0581 0.485 0.96 0.857 1.08 0.043 0.0571 0.451 1.04 0.933 1.17 ukb-melanoma-gwas-catalog all 350.1 Abnormal involuntary movements Neurological Both 1.02 0.948 1.09 0.644 888 8880 FALSE 0.191114132640188 0.0163 0.0352 0.0429 0.0996 0.667 1.04 0.858 1.27 -0.0384 0.101 0.705 0.962 0.789 1.17 0.0856 0.0988 0.386 1.09 0.897 1.32 ukb-melanoma-gwas-catalog all 350.2 Abnormality of gait Neurological Both 1.05 0.993 1.1 0.0924 1599 15990 FALSE 1.03432802877989 0.0443 0.0263 0.0438 0.075 0.559 1.04 0.902 1.21 0.0226 0.0754 0.764 1.02 0.882 1.19 0.101 0.0743 0.176 1.11 0.956 1.28 ukb-melanoma-gwas-catalog all 350.3 Lack of coordination Neurological Both 0.974 0.874 1.08 0.632 364 3640 FALSE 0.199282921717615 -0.0263 0.0549 -0.0467 0.15 0.756 0.954 0.71 1.28 -0.191 0.156 0.221 0.827 0.607 1.12 -0.136 0.153 0.375 0.873 0.645 1.18 ukb-melanoma-gwas-catalog all 351 Other peripheral nerve disorders Neurological Both 0.998 0.98 1.02 0.819 12454 124540 FALSE 0.0867160982395816 -0.00215 0.00943 -0.0391 0.0266 0.142 0.962 0.913 1.01 -0.0205 0.0265 0.44 0.98 0.93 1.03 -0.0163 0.0266 0.54 0.984 0.934 1.04 ukb-melanoma-gwas-catalog all 352 Disorders of other cranial nerves Neurological Both 1.04 0.986 1.1 0.141 1391 13910 FALSE 0.85078088734462 0.0414 0.0282 -0.0464 0.0814 0.569 0.955 0.814 1.12 0.11 0.0787 0.162 1.12 0.957 1.3 0.053 0.0802 0.508 1.05 0.901 1.23 ukb-melanoma-gwas-catalog all 352.1 Trigeminal nerve disorders [CN5] Neurological Both 1.03 0.933 1.13 0.593 463 4630 FALSE 0.226945306635737 0.026 0.0487 -0.127 0.14 0.364 0.881 0.668 1.16 -0.0249 0.137 0.855 0.975 0.745 1.28 0.0193 0.135 0.887 1.02 0.781 1.33 ukb-melanoma-gwas-catalog all 352.2 Facial nerve disorders [CN7] Neurological Both 1.06 0.985 1.13 0.126 880 8800 FALSE 0.899629454882437 0.0541 0.0354 -0.037 0.103 0.719 0.964 0.787 1.18 0.158 0.0988 0.11 1.17 0.965 1.42 0.0713 0.101 0.482 1.07 0.88 1.31 ukb-melanoma-gwas-catalog all 353 Nerve root and plexus disorders Neurological Both 0.978 0.92 1.04 0.476 1137 11370 FALSE 0.322393047279507 -0.0222 0.0312 -0.00747 0.0876 0.932 0.993 0.836 1.18 0.00327 0.0876 0.97 1 0.845 1.19 -0.0404 0.0884 0.648 0.96 0.807 1.14 ukb-melanoma-gwas-catalog all 353.1 Nerve plexus lesions Neurological Both 1.08 0.89 1.31 0.43 114 1140 FALSE 0.366531544420413 0.0766 0.0971 -0.0442 0.284 0.877 0.957 0.541 1.69 0.275 0.269 0.306 1.32 0.775 2.26 0.0966 0.277 0.727 1.1 0.635 1.92 ukb-melanoma-gwas-catalog all 353.2 Nerve root lesions Neurological Both 0.774 0.587 1.02 0.062 57 570 FALSE 1.20760831050175 -0.257 0.138 0.203 0.347 0.558 1.23 0.617 2.47 -0.605 0.412 0.142 0.546 0.229 1.23 -0.34 0.395 0.39 0.712 0.315 1.56 ukb-melanoma-gwas-catalog all 356 Hereditary and idiopathic peripheral neuropathy Neurological Both 0.905 0.764 1.07 0.242 152 1520 FALSE 0.616184634019569 -0.1 0.0854 -0.128 0.227 0.571 0.879 0.56 1.38 -0.28 0.235 0.234 0.756 0.472 1.2 -0.341 0.239 0.154 0.711 0.44 1.14 ukb-melanoma-gwas-catalog all 357 Inflammatory and toxic neuropathy Neurological Both 0.962 0.909 1.02 0.17 1367 13670 FALSE 0.769551078621726 -0.0391 0.0285 -0.00605 0.0784 0.939 0.994 0.852 1.16 -0.0478 0.0793 0.547 0.953 0.816 1.11 -0.156 0.0815 0.0549 0.855 0.728 1 ukb-melanoma-gwas-catalog all 358 Myoneural disorders Neurological Both 1.23 1.07 1.41 0.00435 213 2130 TRUE 2.36151074304536 0.204 0.0716 0.206 0.218 0.346 1.23 0.798 1.9 0.367 0.211 0.0824 1.44 0.954 2.21 0.478 0.208 0.0214 1.61 1.07 2.45 ukb-melanoma-gwas-catalog all 358.1 Myasthenia gravis Neurological Both 1.24 1.07 1.44 0.00489 192 1920 TRUE 2.31069114087638 0.213 0.0757 0.174 0.231 0.452 1.19 0.753 1.89 0.361 0.223 0.105 1.44 0.927 2.24 0.513 0.218 0.0187 1.67 1.09 2.59 ukb-melanoma-gwas-catalog all 359 Muscular dystrophies and other myopathies Neurological Both 0.934 0.849 1.03 0.163 469 4690 FALSE 0.787812395596042 -0.0679 0.0486 -0.0151 0.133 0.91 0.985 0.758 1.28 -0.16 0.138 0.247 0.853 0.649 1.12 -0.11 0.137 0.421 0.896 0.684 1.17 ukb-melanoma-gwas-catalog all 359.1 Muscular dystrophies Neurological Both 0.868 0.718 1.05 0.135 122 1220 FALSE 0.869666231504994 -0.142 0.095 -0.126 0.262 0.63 0.881 0.522 1.48 -0.0822 0.255 0.748 0.921 0.554 1.53 -0.212 0.266 0.426 0.809 0.474 1.37 ukb-melanoma-gwas-catalog all 359.2 Myopathy Neurological Both 0.957 0.858 1.07 0.43 361 3610 FALSE 0.366531544420413 -0.0437 0.0554 -0.00632 0.152 0.967 0.994 0.736 1.34 -0.178 0.159 0.263 0.837 0.611 1.14 -0.0717 0.155 0.644 0.931 0.685 1.26 ukb-melanoma-gwas-catalog all 360 Disorders of the globe Sense Organs Both 1.01 0.899 1.12 0.923 337 3370 FALSE 0.0347982989740879 0.00553 0.057 -0.0819 0.162 0.613 0.921 0.669 1.27 -0.0115 0.16 0.942 0.989 0.721 1.35 0.0162 0.159 0.919 1.02 0.742 1.39 ukb-melanoma-gwas-catalog all 360.2 Progressive myopia Sense Organs Both 1 0.88 1.14 0.97 251 2510 FALSE 0.0132282657337552 0.00249 0.0661 -0.222 0.187 0.234 0.801 0.553 1.16 -0.0991 0.181 0.583 0.906 0.633 1.29 -0.125 0.183 0.496 0.883 0.614 1.27 ukb-melanoma-gwas-catalog all 361 Retinal detachments and defects Sense Organs Both 0.971 0.936 1.01 0.107 3256 32560 FALSE 0.97061622231479 -0.0298 0.0185 -0.0386 0.0517 0.455 0.962 0.869 1.06 -0.0247 0.0516 0.633 0.976 0.882 1.08 -0.0729 0.0522 0.163 0.93 0.839 1.03 ukb-melanoma-gwas-catalog all 361.1 Retinal detachment with retinal defect Sense Organs Both 0.993 0.94 1.05 0.812 1389 13890 FALSE 0.0904439707588247 -0.0067 0.0282 0.0572 0.079 0.469 1.06 0.907 1.24 -0.0436 0.0809 0.59 0.957 0.817 1.12 0.0327 0.0797 0.681 1.03 0.884 1.21 ukb-melanoma-gwas-catalog all 361.2 Retinoschisis and retinal cysts Sense Organs Both 0.973 0.756 1.25 0.826 68 680 FALSE 0.0830199526796178 -0.0276 0.125 -0.213 0.359 0.553 0.808 0.388 1.65 -0.0333 0.339 0.922 0.967 0.49 1.91 0.044 0.343 0.898 1.04 0.524 2.08 ukb-melanoma-gwas-catalog all 362 Other retinal disorders Sense Organs Both 1 0.97 1.04 0.893 3858 38580 FALSE 0.0491485411114536 0.00229 0.0169 0.0408 0.0477 0.393 1.04 0.949 1.14 0.0223 0.0479 0.642 1.02 0.931 1.12 0.000321 0.0483 0.995 1 0.91 1.1 ukb-melanoma-gwas-catalog all 362.2 Degeneration of macula and posterior pole of retina Sense Organs Both 1.02 0.974 1.06 0.424 2184 21840 FALSE 0.372634143407267 0.018 0.0225 0.0514 0.0638 0.421 1.05 0.929 1.19 0.0632 0.0637 0.321 1.07 0.94 1.21 0.034 0.0645 0.598 1.03 0.912 1.17 ukb-melanoma-gwas-catalog all 362.3 Other nondiabetic retinopathy Sense Organs Both 0.96 0.815 1.13 0.623 160 1600 FALSE 0.20551195334083 -0.0407 0.0829 -0.0727 0.232 0.754 0.93 0.585 1.47 0.115 0.223 0.605 1.12 0.722 1.75 -0.135 0.241 0.577 0.874 0.54 1.41 ukb-melanoma-gwas-catalog all 362.4 Retinal vascular changes and abnomalities Sense Organs Both 1.03 0.959 1.1 0.423 847 8470 FALSE 0.373659632624958 0.0289 0.036 -0.0184 0.103 0.858 0.982 0.802 1.2 0.0156 0.102 0.879 1.02 0.831 1.24 0.0632 0.101 0.532 1.07 0.873 1.3 ukb-melanoma-gwas-catalog all 362.6 Peripheral retinal degenerations Sense Organs Both 1.01 0.867 1.18 0.896 183 1830 FALSE 0.0476919903378748 0.0101 0.0772 0.0226 0.221 0.919 1.02 0.66 1.59 0.172 0.214 0.422 1.19 0.779 1.82 0.0402 0.223 0.857 1.04 0.668 1.62 ukb-melanoma-gwas-catalog all 362.7 Hereditary retinal dystrophies Sense Organs Both 0.974 0.775 1.22 0.819 82 820 FALSE 0.0867160982395816 -0.0262 0.114 -0.0878 0.314 0.78 0.916 0.488 1.71 -0.0241 0.31 0.938 0.976 0.525 1.81 -0.233 0.329 0.48 0.792 0.406 1.53 ukb-melanoma-gwas-catalog all 362.8 Retinal hemorrhage/ischemia Sense Organs Both 1.05 0.867 1.27 0.61 116 1160 FALSE 0.214670164989233 0.0493 0.0967 0.408 0.277 0.141 1.5 0.872 2.64 0.257 0.283 0.364 1.29 0.739 2.29 0.172 0.29 0.554 1.19 0.667 2.13 ukb-melanoma-gwas-catalog all 362.29 Macular degeneration (senile) of retina NOS Sense Organs Both 1.02 0.975 1.07 0.393 2181 21810 FALSE 0.405607449624573 0.0192 0.0225 0.0517 0.0639 0.418 1.05 0.929 1.19 0.0635 0.0638 0.32 1.07 0.94 1.21 0.0359 0.0645 0.578 1.04 0.913 1.18 ukb-melanoma-gwas-catalog all 362.31 Separation of retinal layers Sense Organs Both 0.926 0.753 1.14 0.465 99 990 FALSE 0.332547047110046 -0.0764 0.104 -0.0816 0.286 0.775 0.922 0.52 1.63 -0.0667 0.285 0.815 0.936 0.529 1.65 -0.185 0.298 0.535 0.831 0.456 1.5 ukb-melanoma-gwas-catalog all 363 Chorioretinal inflammations, scars, and other disorders of choroid Sense Organs Both 0.892 0.762 1.04 0.151 171 1710 FALSE 0.821023052706831 -0.115 0.0797 -0.14 0.215 0.515 0.869 0.566 1.33 -0.216 0.22 0.327 0.806 0.52 1.24 -0.288 0.224 0.199 0.75 0.478 1.17 ukb-melanoma-gwas-catalog all 363.3 Chorioretinal scars Sense Organs Both 0.817 0.636 1.05 0.104 69 690 FALSE 0.98296666070122 -0.203 0.125 0.128 0.324 0.693 1.14 0.597 2.18 -0.152 0.344 0.659 0.859 0.427 1.71 -0.435 0.369 0.238 0.647 0.301 1.35 ukb-melanoma-gwas-catalog all 364 Corneal opacity and other disorders of cornea Sense Organs Both 0.962 0.888 1.04 0.347 658 6580 FALSE 0.459670525209126 -0.0385 0.041 -0.0613 0.115 0.594 0.941 0.75 1.18 -0.00184 0.113 0.987 0.998 0.799 1.25 -0.1 0.116 0.39 0.905 0.72 1.14 ukb-melanoma-gwas-catalog all 364.2 Corneal edema Sense Organs Both 0.87 0.69 1.09 0.23 80 800 FALSE 0.638272163982407 -0.14 0.116 0.184 0.313 0.556 1.2 0.645 2.26 0.106 0.325 0.745 1.11 0.581 2.13 -0.278 0.35 0.426 0.757 0.368 1.52 ukb-melanoma-gwas-catalog all 364.4 Corneal degenerations Sense Organs Both 1.05 0.908 1.21 0.524 208 2080 FALSE 0.280668713016273 0.0461 0.0725 0.304 0.213 0.154 1.36 0.891 2.08 0.339 0.213 0.11 1.4 0.925 2.15 0.274 0.214 0.2 1.32 0.864 2.02 ukb-melanoma-gwas-catalog all 364.5 Corneal dystrophy Sense Organs Both 1.01 0.878 1.17 0.866 211 2110 FALSE 0.0624821079826534 0.0122 0.0719 0.131 0.203 0.517 1.14 0.765 1.71 0.128 0.203 0.528 1.14 0.762 1.7 0.053 0.209 0.8 1.05 0.697 1.6 ukb-melanoma-gwas-catalog all 364.9 Cornea replaced by transplant Sense Organs Both 1.12 0.91 1.38 0.282 100 1000 FALSE 0.549750891680639 0.112 0.104 0.385 0.309 0.214 1.47 0.799 2.76 0.315 0.316 0.32 1.37 0.731 2.61 0.417 0.306 0.172 1.52 0.832 2.84 ukb-melanoma-gwas-catalog all 364.41 Keratoconus Sense Organs Both 1.04 0.834 1.3 0.726 87 870 FALSE 0.139063379299906 0.0389 0.111 0.05 0.331 0.88 1.05 0.539 2.06 0.528 0.306 0.0844 1.69 0.933 3.16 0.0249 0.331 0.94 1.03 0.526 2.01 ukb-melanoma-gwas-catalog all 365 Glaucoma Sense Organs Both 0.988 0.958 1.02 0.461 4430 44300 FALSE 0.336299074610352 -0.0116 0.0158 -0.0667 0.0445 0.133 0.935 0.857 1.02 -0.0302 0.0442 0.494 0.97 0.89 1.06 -0.0625 0.0446 0.161 0.939 0.861 1.03 ukb-melanoma-gwas-catalog all 365.1 Open-angle glaucoma Sense Organs Both 1.02 0.955 1.09 0.58 1029 10290 FALSE 0.236572006437063 0.0181 0.0328 0.0605 0.0925 0.513 1.06 0.886 1.27 0.0237 0.0932 0.799 1.02 0.853 1.23 0.0384 0.0932 0.681 1.04 0.865 1.25 ukb-melanoma-gwas-catalog all 365.2 Primary angle-closure glaucoma Sense Organs Both 1.02 0.941 1.1 0.658 700 7000 FALSE 0.181774106386044 0.0176 0.0397 -0.048 0.114 0.674 0.953 0.762 1.19 0.107 0.11 0.331 1.11 0.897 1.38 -0.0155 0.114 0.891 0.985 0.787 1.23 ukb-melanoma-gwas-catalog all 365.11 Primary open angle glaucoma Sense Organs Both 1.02 0.958 1.09 0.518 1023 10230 FALSE 0.285670240254767 0.0212 0.0328 0.0648 0.0927 0.484 1.07 0.889 1.28 0.0281 0.0935 0.764 1.03 0.856 1.24 0.0387 0.0935 0.679 1.04 0.865 1.25 ukb-melanoma-gwas-catalog all 366 Cataract Sense Organs Both 0.997 0.982 1.01 0.664 19997 169205 FALSE 0.177831920631982 -0.00327 0.00752 0.000134 0.0211 0.995 1 0.96 1.04 -0.0367 0.0213 0.085 0.964 0.924 1.01 -0.00491 0.0212 0.817 0.995 0.955 1.04 ukb-melanoma-gwas-catalog all 366.1 Nonsenile Cataract Sense Organs Both 1.26 0.981 1.61 0.0678 70 700 FALSE 1.16877030613294 0.228 0.125 0.449 0.395 0.256 1.57 0.713 3.59 0.801 0.378 0.0338 2.23 1.07 4.95 0.642 0.381 0.0922 1.9 0.898 4.25 ukb-melanoma-gwas-catalog all 366.2 Senile cataract Sense Organs Both 1 0.979 1.02 0.933 8261 82116 FALSE 0.0301183562535 0.000968 0.0116 0.0198 0.0325 0.541 1.02 0.957 1.09 -0.0334 0.0329 0.31 0.967 0.907 1.03 0.00554 0.0327 0.866 1.01 0.943 1.07 ukb-melanoma-gwas-catalog all 366.3 Traumatic cataract Sense Organs Both 1.07 0.874 1.31 0.498 102 1020 FALSE 0.302770657240282 0.0695 0.103 0.0511 0.282 0.856 1.05 0.6 1.85 -0.261 0.307 0.396 0.771 0.413 1.42 0.0701 0.28 0.803 1.07 0.614 1.88 ukb-melanoma-gwas-catalog all 367 Disorders of refraction and accommodation; blindness and low vision Sense Organs Both 0.994 0.953 1.04 0.76 2428 24280 FALSE 0.119186407719209 -0.00651 0.0214 0.00154 0.0602 0.98 1 0.89 1.13 0.0445 0.0597 0.456 1.05 0.93 1.18 -0.0466 0.0612 0.446 0.954 0.846 1.08 ukb-melanoma-gwas-catalog all 367.1 Myopia Sense Organs Both 0.997 0.941 1.06 0.921 1255 12550 FALSE 0.0357403698031511 -0.00296 0.0297 0.00433 0.0832 0.959 1 0.853 1.18 -0.0383 0.0841 0.649 0.962 0.816 1.14 0.000783 0.0838 0.993 1 0.849 1.18 ukb-melanoma-gwas-catalog all 367.2 Astigmatism Sense Organs Both 0.897 0.771 1.04 0.158 190 1900 FALSE 0.801342913045577 -0.108 0.0765 -0.196 0.213 0.357 0.822 0.538 1.25 0.000784 0.204 0.997 1 0.669 1.5 -0.335 0.221 0.129 0.716 0.46 1.1 ukb-melanoma-gwas-catalog all 367.8 Hypermetropia Sense Organs Both 0.998 0.876 1.14 0.98 252 2520 FALSE 0.00877392430750515 -0.0017 0.066 -0.119 0.185 0.52 0.888 0.616 1.28 -0.00991 0.181 0.956 0.99 0.693 1.41 -0.157 0.187 0.403 0.855 0.589 1.24 ukb-melanoma-gwas-catalog all 367.9 Blindness and low vision Sense Organs Both 1.02 0.946 1.1 0.593 723 7230 FALSE 0.226945306635737 0.0209 0.039 -0.0174 0.112 0.877 0.983 0.788 1.23 0.111 0.109 0.307 1.12 0.903 1.39 0.0148 0.111 0.894 1.01 0.815 1.26 ukb-melanoma-gwas-catalog all 368 Visual disturbances Sense Organs Both 1.02 0.982 1.06 0.303 2990 29900 FALSE 0.518557371497695 0.0198 0.0192 -0.0181 0.0548 0.742 0.982 0.882 1.09 0.0459 0.0541 0.396 1.05 0.942 1.16 0.0316 0.0544 0.561 1.03 0.928 1.15 ukb-melanoma-gwas-catalog all 368.1 Amblyopia Sense Organs Both 1.02 0.931 1.11 0.701 535 5350 FALSE 0.154281982033341 0.0174 0.0453 0.21 0.13 0.108 1.23 0.955 1.6 0.3 0.128 0.0195 1.35 1.05 1.74 0.0547 0.135 0.686 1.06 0.809 1.38 ukb-melanoma-gwas-catalog all 368.2 Diplopia and disorders of binocular vision Sense Organs Both 0.994 0.921 1.07 0.885 730 7300 FALSE 0.0530567293021746 -0.00564 0.0389 -0.0726 0.109 0.505 0.93 0.751 1.15 -0.134 0.111 0.228 0.875 0.703 1.09 0.00668 0.107 0.95 1.01 0.815 1.24 ukb-melanoma-gwas-catalog all 368.3 Anisometropia Sense Organs Both 1.11 0.938 1.31 0.224 155 1550 FALSE 0.649751981665837 0.102 0.0839 -0.142 0.247 0.565 0.868 0.529 1.42 0.0308 0.24 0.898 1.03 0.64 1.66 0.247 0.23 0.284 1.28 0.813 2.03 ukb-melanoma-gwas-catalog all 368.9 Subjective visual disturbances Sense Organs Both 1.05 0.966 1.14 0.252 614 6140 FALSE 0.598599459218456 0.0484 0.0423 -0.0665 0.12 0.579 0.936 0.739 1.18 -0.042 0.119 0.725 0.959 0.758 1.21 0.014 0.118 0.906 1.01 0.804 1.28 ukb-melanoma-gwas-catalog all 369 Infection of the eye Sense Organs Both 0.977 0.895 1.07 0.598 560 5600 FALSE 0.223298816011589 -0.0234 0.0444 -0.126 0.127 0.318 0.881 0.687 1.13 0.0605 0.121 0.617 1.06 0.838 1.35 -0.11 0.127 0.385 0.896 0.698 1.15 ukb-melanoma-gwas-catalog all 369.2 Eye infection, viral Sense Organs Both 1.04 0.863 1.25 0.686 126 1260 FALSE 0.163675884293248 0.0377 0.0931 -0.132 0.27 0.625 0.876 0.51 1.5 0.193 0.253 0.445 1.21 0.736 2.01 -0.0252 0.266 0.924 0.975 0.574 1.66 ukb-melanoma-gwas-catalog all 369.5 Conjunctivitis, infectious Sense Organs Both 0.962 0.835 1.11 0.586 213 2130 FALSE 0.232102383981909 -0.0391 0.0717 0.031 0.198 0.875 1.03 0.698 1.53 -0.103 0.203 0.61 0.902 0.603 1.35 -0.0588 0.202 0.772 0.943 0.631 1.41 ukb-melanoma-gwas-catalog all 370 Keratitis Sense Organs Both 0.961 0.852 1.08 0.513 297 2970 FALSE 0.289882634888184 -0.04 0.0611 0.288 0.171 0.0922 1.33 0.954 1.87 0.155 0.176 0.378 1.17 0.826 1.66 0.058 0.18 0.747 1.06 0.743 1.51 ukb-melanoma-gwas-catalog all 370.1 Corneal ulcer Sense Organs Both 0.997 0.838 1.18 0.971 141 1410 FALSE 0.0127807700919951 -0.00315 0.0876 0.294 0.247 0.235 1.34 0.824 2.21 0.291 0.248 0.242 1.34 0.82 2.2 0.0161 0.264 0.951 1.02 0.6 1.72 ukb-melanoma-gwas-catalog all 371 Inflammation of the eye Sense Organs Both 1.01 0.971 1.05 0.69 3168 31680 FALSE 0.161150909262745 0.00745 0.0187 -0.0329 0.0531 0.535 0.968 0.872 1.07 -0.014 0.0529 0.792 0.986 0.889 1.09 0.0318 0.0524 0.545 1.03 0.931 1.14 ukb-melanoma-gwas-catalog all 371.1 Uveitis, noninfectious or NOS Sense Organs Both 0.992 0.903 1.09 0.863 486 4860 FALSE 0.0639892042847904 -0.00823 0.0476 -0.209 0.138 0.128 0.811 0.618 1.06 0.0602 0.13 0.642 1.06 0.823 1.37 -0.0577 0.133 0.666 0.944 0.726 1.23 ukb-melanoma-gwas-catalog all 371.3 Inflammation of eyelids Sense Organs Both 1.02 0.973 1.06 0.477 2391 23910 FALSE 0.321481620959886 0.0153 0.0215 0.00453 0.0613 0.941 1 0.891 1.13 0.0246 0.061 0.686 1.02 0.909 1.16 0.0542 0.0607 0.372 1.06 0.937 1.19 ukb-melanoma-gwas-catalog all 372 Disorders of conjunctiva Sense Organs Both 1.02 0.946 1.1 0.614 764 7640 FALSE 0.211831628858832 0.0192 0.038 -0.113 0.107 0.292 0.893 0.723 1.1 -0.157 0.109 0.148 0.855 0.69 1.06 0.0408 0.104 0.695 1.04 0.849 1.28 ukb-melanoma-gwas-catalog all 374 Other disorders of eyelids Sense Organs Both 1.01 0.982 1.04 0.497 5700 57000 FALSE 0.303643611266668 0.00947 0.0139 -0.00073 0.0393 0.985 0.999 0.925 1.08 -0.0301 0.0396 0.446 0.97 0.898 1.05 0.0213 0.0392 0.587 1.02 0.946 1.1 ukb-melanoma-gwas-catalog all 374.1 Ectropion or entropion Sense Organs Both 1.04 0.974 1.1 0.257 1066 10660 FALSE 0.590066876668705 0.0365 0.0322 -0.0577 0.0911 0.526 0.944 0.789 1.13 -0.136 0.0928 0.142 0.873 0.727 1.05 0.0874 0.0885 0.324 1.09 0.917 1.3 ukb-melanoma-gwas-catalog all 374.3 Ptosis of eyelid Sense Organs Both 0.992 0.945 1.04 0.748 1826 18260 FALSE 0.126098402135539 -0.00791 0.0246 -0.0959 0.0696 0.168 0.909 0.792 1.04 -0.0562 0.0691 0.416 0.945 0.825 1.08 -0.00965 0.0686 0.888 0.99 0.866 1.13 ukb-melanoma-gwas-catalog all 375 Disorders of lacrimal system Sense Organs Both 1.04 0.994 1.08 0.0933 2213 22130 FALSE 1.0301183562535 0.0375 0.0223 -0.0466 0.0637 0.465 0.954 0.842 1.08 -0.0682 0.064 0.287 0.934 0.824 1.06 0.0962 0.0619 0.12 1.1 0.975 1.24 ukb-melanoma-gwas-catalog all 375.2 Epiphora Sense Organs Both 1.06 0.988 1.13 0.104 899 8990 FALSE 0.98296666070122 0.0568 0.035 -0.128 0.101 0.203 0.879 0.721 1.07 -0.132 0.101 0.192 0.877 0.719 1.07 0.144 0.0952 0.131 1.15 0.958 1.39 ukb-melanoma-gwas-catalog all 376 Disorders of the orbit Sense Organs Both 1.02 0.814 1.27 0.867 86 860 FALSE 0.0619809025237897 0.0189 0.113 0.21 0.3 0.484 1.23 0.681 2.26 -0.249 0.334 0.455 0.78 0.396 1.51 -0.0154 0.322 0.962 0.985 0.517 1.88 ukb-melanoma-gwas-catalog all 377 Disorders of optic nerve and visual pathways Sense Organs Both 1.15 1.04 1.28 0.00897 370 3700 TRUE 2.04720755695591 0.143 0.0547 0.344 0.165 0.0372 1.41 1.02 1.96 0.433 0.162 0.00765 1.54 1.12 2.13 0.427 0.163 0.00885 1.53 1.11 2.12 ukb-melanoma-gwas-catalog all 377.1 Optic atrophy Sense Organs Both 0.975 0.744 1.28 0.851 58 580 FALSE 0.0700704399154121 -0.0254 0.135 0.0461 0.374 0.902 1.05 0.493 2.24 0.189 0.367 0.607 1.21 0.581 2.55 -0.244 0.397 0.54 0.784 0.347 1.74 ukb-melanoma-gwas-catalog all 377.3 Optic neuritis/neuropathy Sense Organs Both 1.17 0.973 1.41 0.0928 125 1250 FALSE 1.03245202378114 0.158 0.0941 0.325 0.283 0.252 1.38 0.79 2.46 0.423 0.278 0.128 1.53 0.884 2.69 0.514 0.276 0.0624 1.67 0.974 2.93 ukb-melanoma-gwas-catalog all 378 Strabismus and other disorders of binocular eye movements Sense Organs Both 1.05 0.995 1.11 0.0721 1437 14370 FALSE 1.14206473528057 0.0498 0.0277 0.203 0.078 0.00938 1.22 1.05 1.43 0.00648 0.0816 0.937 1.01 0.858 1.18 0.152 0.0794 0.0561 1.16 0.996 1.36 ukb-melanoma-gwas-catalog all 378.1 Strabismus (not specified as paralytic) Sense Organs Both 1.03 0.967 1.11 0.322 915 9150 FALSE 0.492144128304169 0.0344 0.0347 0.251 0.097 0.00962 1.29 1.06 1.56 0.022 0.102 0.83 1.02 0.836 1.25 0.105 0.101 0.296 1.11 0.912 1.35 ukb-melanoma-gwas-catalog all 378.2 Nystagmus and other irregular eye movements Sense Organs Both 1.13 0.982 1.3 0.0852 214 2140 FALSE 1.0695604052333 0.123 0.0713 0.175 0.213 0.409 1.19 0.783 1.82 0.227 0.21 0.28 1.26 0.83 1.91 0.414 0.204 0.0429 1.51 1.01 2.28 ukb-melanoma-gwas-catalog all 378.5 Paralytic strabismus Sense Organs Both 1.01 0.89 1.14 0.905 276 2760 FALSE 0.0433514207947967 0.00756 0.063 0.176 0.174 0.311 1.19 0.847 1.68 -0.0369 0.183 0.84 0.964 0.671 1.38 -0.0228 0.18 0.899 0.977 0.684 1.4 ukb-melanoma-gwas-catalog all 379 Other disorders of eye Sense Organs Both 0.997 0.964 1.03 0.864 3740 37400 FALSE 0.0634862575211067 -0.00295 0.0172 0.0517 0.0481 0.283 1.05 0.958 1.16 -0.038 0.0492 0.439 0.963 0.874 1.06 0.0169 0.0487 0.728 1.02 0.924 1.12 ukb-melanoma-gwas-catalog all 379.2 Disorders of vitreous body Sense Organs Both 0.977 0.924 1.03 0.406 1368 13680 FALSE 0.391473966422806 -0.0237 0.0284 0.108 0.0778 0.166 1.11 0.956 1.3 -0.13 0.0822 0.113 0.878 0.747 1.03 -0.05 0.0808 0.536 0.951 0.812 1.11 ukb-melanoma-gwas-catalog all 379.3 Aphakia and other disorders of lens Sense Organs Both 1.02 0.968 1.07 0.532 1810 18100 FALSE 0.274088367704952 0.0154 0.0247 0.0146 0.07 0.835 1.01 0.884 1.16 0.016 0.0701 0.819 1.02 0.886 1.17 0.0479 0.0697 0.492 1.05 0.915 1.2 ukb-melanoma-gwas-catalog all 379.4 Anomalies of pupillary function Sense Organs Both 0.832 0.644 1.07 0.147 70 700 FALSE 0.832682665251824 -0.184 0.127 -0.0385 0.317 0.903 0.962 0.51 1.81 -0.687 0.382 0.0719 0.503 0.225 1.06 -0.222 0.343 0.517 0.801 0.399 1.58 ukb-melanoma-gwas-catalog all 379.5 Disorders of iris and ciliary body Sense Organs Both 0.982 0.885 1.09 0.723 401 4010 FALSE 0.140861702705469 -0.0186 0.0524 -0.176 0.15 0.242 0.839 0.623 1.13 0.0435 0.143 0.76 1.04 0.789 1.38 -0.0867 0.148 0.557 0.917 0.685 1.23 ukb-melanoma-gwas-catalog all 380 Disorders of external ear Sense Organs Both 1.09 1 1.18 0.0379 643 6430 TRUE 1.42136079003193 0.0859 0.0414 -0.011 0.124 0.929 0.989 0.776 1.26 0.14 0.12 0.245 1.15 0.908 1.46 0.312 0.116 0.00713 1.37 1.09 1.72 ukb-melanoma-gwas-catalog all 381 Otitis media and Eustachian tube disorders Sense Organs Both 1.04 0.993 1.08 0.102 2253 22530 FALSE 0.991399828238082 0.0363 0.0222 0.0811 0.0628 0.197 1.08 0.959 1.23 0.0069 0.0639 0.914 1.01 0.888 1.14 0.103 0.0629 0.103 1.11 0.98 1.25 ukb-melanoma-gwas-catalog all 381.1 Otitis media Sense Organs Both 1.05 1 1.1 0.037 1820 18200 TRUE 1.43179827593301 0.0514 0.0247 0.109 0.0701 0.12 1.12 0.972 1.28 0.0108 0.0717 0.88 1.01 0.878 1.16 0.15 0.07 0.0319 1.16 1.01 1.33 ukb-melanoma-gwas-catalog all 381.2 Eustachian tube disorders Sense Organs Both 0.939 0.808 1.09 0.409 191 1910 FALSE 0.388276691992658 -0.0627 0.0758 -0.337 0.219 0.124 0.714 0.46 1.1 0.148 0.199 0.458 1.16 0.784 1.72 -0.277 0.218 0.203 0.758 0.491 1.16 ukb-melanoma-gwas-catalog all 381.3 Mastoiditis & related conditions Sense Organs Both 0.907 0.773 1.06 0.223 171 1710 FALSE 0.651695136951839 -0.0979 0.0803 -0.00617 0.213 0.977 0.994 0.652 1.51 -0.311 0.23 0.177 0.733 0.462 1.15 -0.22 0.226 0.332 0.803 0.511 1.25 ukb-melanoma-gwas-catalog all 381.9 Otorrhea Sense Organs Both 1.04 0.916 1.17 0.567 280 2800 FALSE 0.246416941107093 0.0359 0.0627 0.0335 0.177 0.85 1.03 0.729 1.47 0.0224 0.177 0.9 1.02 0.721 1.45 0.0282 0.178 0.874 1.03 0.724 1.46 ukb-melanoma-gwas-catalog all 381.11 Suppurative and unspecified otitis media Sense Organs Both 1.08 1 1.15 0.0414 854 8540 TRUE 1.3829996588791 0.0734 0.036 0.162 0.103 0.117 1.18 0.96 1.44 0.0505 0.106 0.633 1.05 0.854 1.3 0.23 0.103 0.0251 1.26 1.03 1.54 ukb-melanoma-gwas-catalog all 382 Otalgia Sense Organs Both 0.995 0.884 1.12 0.931 309 3090 FALSE 0.0310503190186573 -0.00518 0.0597 0.153 0.165 0.352 1.17 0.843 1.62 -0.0179 0.171 0.917 0.982 0.7 1.38 0.0059 0.171 0.973 1.01 0.717 1.41 ukb-melanoma-gwas-catalog all 383 Otosclerosis Sense Organs Both 1.07 0.947 1.2 0.288 309 3090 FALSE 0.540607512240769 0.0634 0.0597 0.0265 0.174 0.879 1.03 0.729 1.45 0.221 0.166 0.183 1.25 0.9 1.73 0.0496 0.172 0.774 1.05 0.748 1.48 ukb-melanoma-gwas-catalog all 384 Other disorders of tympanic membrane Sense Organs Both 0.966 0.914 1.02 0.231 1362 13620 FALSE 0.636388020107856 -0.0342 0.0285 0.0459 0.0792 0.563 1.05 0.896 1.22 -0.0102 0.0803 0.899 0.99 0.845 1.16 -0.066 0.0818 0.42 0.936 0.797 1.1 ukb-melanoma-gwas-catalog all 384.4 Perforation of tympanic membrane Sense Organs Both 0.984 0.923 1.05 0.613 1043 10430 FALSE 0.212539525481585 -0.0165 0.0326 0.0469 0.0914 0.608 1.05 0.876 1.25 0.0625 0.0913 0.493 1.06 0.89 1.27 -0.0549 0.094 0.56 0.947 0.787 1.14 ukb-melanoma-gwas-catalog all 385 Other disorders of middle ear and mastoid Sense Organs Both 1.02 0.951 1.1 0.55 827 8270 FALSE 0.259637310505756 0.0219 0.0366 0.0553 0.102 0.588 1.06 0.865 1.29 0.0136 0.104 0.895 1.01 0.827 1.24 -0.0394 0.105 0.707 0.961 0.782 1.18 ukb-melanoma-gwas-catalog all 385.3 Cholesteatoma Sense Organs Both 1.02 0.941 1.11 0.589 607 6070 FALSE 0.229884705212898 0.0231 0.0426 0.00767 0.118 0.948 1.01 0.798 1.27 -0.0372 0.12 0.757 0.963 0.76 1.22 -0.0769 0.122 0.527 0.926 0.729 1.18 ukb-melanoma-gwas-catalog all 385.5 Tympanosclerosis and middle ear disease related to otitis media Sense Organs Both 1.01 0.886 1.16 0.857 241 2410 FALSE 0.0670191780768018 0.0121 0.0674 0.0318 0.188 0.866 1.03 0.712 1.5 0.0197 0.189 0.917 1.02 0.702 1.48 -0.0539 0.192 0.779 0.947 0.647 1.39 ukb-melanoma-gwas-catalog all 386 Vertiginous syndromes and other disorders of vestibular system Sense Organs Both 1.01 0.965 1.06 0.595 1765 17650 FALSE 0.22548303427145 0.0133 0.025 0.0834 0.0702 0.235 1.09 0.947 1.25 -0.00433 0.0717 0.952 0.996 0.865 1.15 0.0486 0.0711 0.494 1.05 0.913 1.21 ukb-melanoma-gwas-catalog all 386.1 Meniere's disease Sense Organs Both 1.04 0.956 1.13 0.352 578 5780 FALSE 0.453457336521869 0.0405 0.0436 0.105 0.125 0.401 1.11 0.868 1.42 0.166 0.124 0.18 1.18 0.926 1.51 0.114 0.126 0.365 1.12 0.875 1.44 ukb-melanoma-gwas-catalog all 386.2 Peripheral or central vertigo Sense Organs Both 0.98 0.881 1.09 0.704 379 3790 FALSE 0.152427340857888 -0.0204 0.0538 0.00546 0.145 0.97 1.01 0.756 1.34 -0.311 0.157 0.0472 0.733 0.537 0.996 -0.105 0.149 0.48 0.9 0.671 1.21 ukb-melanoma-gwas-catalog all 386.3 Labyrinthitis Sense Organs Both 1 0.933 1.08 0.896 767 7670 FALSE 0.0476919903378748 0.00496 0.0379 0.0643 0.106 0.546 1.07 0.865 1.31 -0.0381 0.109 0.727 0.963 0.777 1.19 0.0666 0.107 0.534 1.07 0.866 1.32 ukb-melanoma-gwas-catalog all 386.9 Dizziness and giddiness (Light-headedness and vertigo) Sense Organs Both 1.09 0.954 1.24 0.207 243 2430 FALSE 0.684029654543082 0.0841 0.0667 -0.0586 0.199 0.768 0.943 0.636 1.4 0.169 0.189 0.372 1.18 0.816 1.72 0.201 0.187 0.282 1.22 0.847 1.77 ukb-melanoma-gwas-catalog all 388 Other disorders of ear Sense Organs Both 1.1 0.949 1.27 0.209 202 2020 FALSE 0.679853713888946 0.0924 0.0736 0.0289 0.217 0.894 1.03 0.669 1.59 0.169 0.212 0.424 1.18 0.78 1.81 0.323 0.208 0.12 1.38 0.918 2.09 ukb-melanoma-gwas-catalog all 389 Hearing loss Sense Organs Both 1.04 1.01 1.07 0.0231 4243 42430 TRUE 1.63638802010786 0.0367 0.0162 0.0316 0.0461 0.492 1.03 0.943 1.13 0.037 0.0461 0.422 1.04 0.948 1.14 0.0898 0.0457 0.0494 1.09 1 1.2 ukb-melanoma-gwas-catalog all 389.1 Sensorineural hearing loss Sense Organs Both 0.989 0.898 1.09 0.826 456 4560 FALSE 0.0830199526796178 -0.0108 0.0492 -0.172 0.14 0.22 0.842 0.639 1.11 -0.0416 0.137 0.761 0.959 0.733 1.25 -0.0421 0.136 0.758 0.959 0.733 1.25 ukb-melanoma-gwas-catalog all 389.2 Conductive hearing loss Sense Organs Both 1.11 1 1.22 0.0403 450 4500 TRUE 1.39469495385889 0.101 0.0494 -0.0468 0.143 0.744 0.954 0.719 1.27 -0.142 0.147 0.334 0.868 0.649 1.16 0.288 0.134 0.0313 1.33 1.03 1.74 ukb-melanoma-gwas-catalog all 389.4 Tinnitus Sense Organs Both 0.979 0.893 1.07 0.644 512 5120 FALSE 0.191114132640188 -0.0215 0.0465 0.179 0.128 0.16 1.2 0.931 1.54 -0.0371 0.134 0.782 0.964 0.74 1.25 -0.0304 0.134 0.821 0.97 0.744 1.26 ukb-melanoma-gwas-catalog all 394 Rheumatic disease of the heart valves Circulatory System Both 1.01 0.981 1.04 0.492 4912 49120 FALSE 0.30803489723264 0.0103 0.015 0.0544 0.0425 0.2 1.06 0.972 1.15 0.0444 0.0426 0.297 1.05 0.962 1.14 0.0365 0.0428 0.394 1.04 0.954 1.13 ukb-melanoma-gwas-catalog all 394.2 Mitral valve disease Circulatory System Both 1.02 0.98 1.06 0.372 2992 29920 FALSE 0.429457060118102 0.0172 0.0192 0.0011 0.0544 0.984 1 0.9 1.11 -0.0042 0.0545 0.939 0.996 0.895 1.11 0.0244 0.0543 0.653 1.02 0.921 1.14 ukb-melanoma-gwas-catalog all 394.3 Aortic valve disease Circulatory System Both 1.03 0.977 1.1 0.243 1283 12830 FALSE 0.614393726401688 0.0342 0.0293 0.181 0.0837 0.0306 1.2 1.02 1.41 0.11 0.0849 0.197 1.12 0.945 1.32 0.153 0.0846 0.0709 1.17 0.987 1.38 ukb-melanoma-gwas-catalog all 394.7 Disease of tricuspid valve Circulatory System Both 1.03 0.968 1.1 0.341 1054 10540 FALSE 0.467245621007502 0.0308 0.0323 0.0727 0.0928 0.433 1.08 0.896 1.29 0.106 0.092 0.249 1.11 0.928 1.33 0.087 0.0928 0.348 1.09 0.909 1.31 ukb-melanoma-gwas-catalog all 395 Heart valve disorders Circulatory System Both 1.02 0.99 1.05 0.187 4249 42490 FALSE 0.728158393463501 0.0213 0.0161 -0.0188 0.0457 0.682 0.981 0.897 1.07 0.00328 0.0456 0.943 1 0.918 1.1 0.0186 0.0455 0.682 1.02 0.932 1.11 ukb-melanoma-gwas-catalog all 395.1 Nonrheumatic mitral valve disorders Circulatory System Both 1.01 0.973 1.05 0.558 2892 28920 FALSE 0.253365801062421 0.0115 0.0196 -0.0333 0.0552 0.547 0.967 0.868 1.08 -0.0342 0.0553 0.537 0.966 0.867 1.08 0.00231 0.055 0.966 1 0.9 1.12 ukb-melanoma-gwas-catalog all 395.2 Nonrheumatic aortic valve disorders Circulatory System Both 0.974 0.861 1.1 0.676 278 2780 FALSE 0.170053304058364 -0.0262 0.0628 -0.275 0.182 0.132 0.76 0.529 1.09 -0.0362 0.173 0.834 0.964 0.686 1.36 0.00667 0.172 0.969 1.01 0.717 1.41 ukb-melanoma-gwas-catalog all 395.3 Nonrheumatic tricuspid valve disorders Circulatory System Both 1.15 0.939 1.41 0.174 104 1040 FALSE 0.7594507517174 0.139 0.102 -0.167 0.307 0.586 0.846 0.454 1.56 0.144 0.285 0.613 1.15 0.655 2.05 0.245 0.279 0.38 1.28 0.736 2.24 ukb-melanoma-gwas-catalog all 395.4 Nonrheumatic pulmonary valve disorders Circulatory System Both 0.876 0.708 1.08 0.214 96 960 FALSE 0.669586226650809 -0.133 0.107 -0.706 0.301 0.019 0.494 0.266 0.887 -0.417 0.279 0.135 0.659 0.374 1.14 -0.505 0.287 0.0782 0.603 0.337 1.06 ukb-melanoma-gwas-catalog all 395.6 Heart valve replaced Circulatory System Both 1.06 1.01 1.12 0.0225 1494 14940 TRUE 1.64781748188864 0.0619 0.0271 0.199 0.0777 0.0105 1.22 1.05 1.42 0.151 0.0785 0.0542 1.16 0.997 1.36 0.139 0.0791 0.0783 1.15 0.984 1.34 ukb-melanoma-gwas-catalog all 396 Abnormal heart sounds Circulatory System Both 0.987 0.926 1.05 0.681 1049 10490 FALSE 0.166852888087215 -0.0134 0.0325 0.028 0.092 0.761 1.03 0.858 1.23 0.0634 0.0912 0.487 1.07 0.891 1.27 -0.0123 0.093 0.895 0.988 0.823 1.19 ukb-melanoma-gwas-catalog all 401 Hypertension Circulatory System Both 1.02 1.01 1.03 0.00011 74203 267481 TRUE 3.95860731484178 0.0167 0.00431 0.0183 0.0122 0.135 1.02 0.994 1.04 0.0259 0.0122 0.0336 1.03 1 1.05 0.0414 0.0122 0.000701 1.04 1.02 1.07 ukb-melanoma-gwas-catalog all 401.1 Essential hypertension Circulatory System Both 1.02 1.01 1.03 0.00015 73892 266307 TRUE 3.82390874094432 0.0164 0.00432 0.0187 0.0123 0.127 1.02 0.995 1.04 0.0263 0.0122 0.0318 1.03 1 1.05 0.0406 0.0123 0.00091 1.04 1.02 1.07 ukb-melanoma-gwas-catalog all 401.2 Hypertensive heart and/or renal disease Circulatory System Both 1.08 1.03 1.14 0.000869 1910 19099 TRUE 3.06098022355133 0.0799 0.024 0.0403 0.0701 0.565 1.04 0.907 1.19 0.123 0.0689 0.0743 1.13 0.988 1.29 0.186 0.0682 0.00632 1.2 1.05 1.38 ukb-melanoma-gwas-catalog all 401.3 Other hypertensive complications Circulatory System Both 1.14 0.957 1.35 0.143 144 1440 FALSE 0.844663962534938 0.127 0.0869 0.321 0.258 0.213 1.38 0.83 2.32 0.337 0.257 0.19 1.4 0.844 2.35 0.419 0.256 0.102 1.52 0.919 2.55 ukb-melanoma-gwas-catalog all 401.21 Hypertensive heart disease Circulatory System Both 1.06 0.957 1.19 0.249 370 3700 FALSE 0.603800652904264 0.0628 0.0544 -0.146 0.159 0.358 0.864 0.631 1.18 -0.0354 0.155 0.82 0.965 0.71 1.31 0.185 0.148 0.213 1.2 0.899 1.61 ukb-melanoma-gwas-catalog all 401.22 Hypertensive chronic kidney disease Circulatory System Both 1.08 1.03 1.14 0.00347 1551 15510 TRUE 2.45967052520913 0.0779 0.0266 0.0864 0.0771 0.263 1.09 0.937 1.27 0.141 0.0763 0.0643 1.15 0.992 1.34 0.143 0.0765 0.0609 1.15 0.993 1.34 ukb-melanoma-gwas-catalog all 402 Elevated blood pressure reading without diagnosis of hypertension Circulatory System Both 1 0.949 1.06 0.966 1481 14810 FALSE 0.0150228735845067 0.00117 0.0273 0.131 0.0763 0.085 1.14 0.982 1.32 0.0328 0.0779 0.674 1.03 0.887 1.2 -0.0121 0.079 0.878 0.988 0.846 1.15 ukb-melanoma-gwas-catalog all 411 Ischemic Heart Disease Circulatory System Both 1.01 1 1.03 0.0249 31407 211307 TRUE 1.60380065290426 0.0138 0.00613 0.0287 0.0174 0.0989 1.03 0.995 1.06 0.0303 0.0174 0.0822 1.03 0.996 1.07 0.0457 0.0174 0.00865 1.05 1.01 1.08 ukb-melanoma-gwas-catalog all 411.1 Unstable angina (intermediate coronary syndrome) Circulatory System Both 1.03 0.998 1.06 0.0707 5161 51604 FALSE 1.1505805862031 0.0265 0.0146 0.0319 0.0418 0.446 1.03 0.951 1.12 0.0489 0.0417 0.24 1.05 0.968 1.14 0.0729 0.0415 0.0793 1.08 0.991 1.17 ukb-melanoma-gwas-catalog all 411.2 Myocardial infarction Circulatory System Both 1.02 0.999 1.04 0.0623 11981 112940 FALSE 1.20551195334083 0.018 0.00964 0.0393 0.0274 0.152 1.04 0.986 1.1 0.0335 0.0274 0.221 1.03 0.98 1.09 0.0557 0.0274 0.042 1.06 1 1.12 ukb-melanoma-gwas-catalog all 411.3 Angina pectoris Circulatory System Both 1.03 1.02 1.05 0.000133 15926 144026 TRUE 3.87614835903291 0.032 0.00838 0.0515 0.024 0.0318 1.05 1 1.1 0.0517 0.024 0.0312 1.05 1 1.1 0.104 0.0238 1.24e-05 1.11 1.06 1.16 ukb-melanoma-gwas-catalog all 411.4 Coronary atherosclerosis Circulatory System Both 1.02 1 1.03 0.0259 20207 154941 TRUE 1.58670023591875 0.0168 0.00754 0.0241 0.0214 0.261 1.02 0.982 1.07 0.0289 0.0214 0.177 1.03 0.987 1.07 0.0536 0.0214 0.0122 1.06 1.01 1.1 ukb-melanoma-gwas-catalog all 411.8 Other chronic ischemic heart disease, unspecified Circulatory System Both 1.02 1 1.04 0.0286 15331 132062 TRUE 1.54363396687096 0.0188 0.00857 0.0269 0.0243 0.268 1.03 0.979 1.08 0.0176 0.0244 0.47 1.02 0.97 1.07 0.0481 0.0243 0.0476 1.05 1 1.1 ukb-melanoma-gwas-catalog all 411.9 Other acute and subacute forms of ischemic heart disease Circulatory System Both 0.975 0.919 1.03 0.402 1218 12180 FALSE 0.39577394691553 -0.0252 0.0301 -0.077 0.0842 0.361 0.926 0.785 1.09 -0.099 0.0847 0.242 0.906 0.767 1.07 -0.0468 0.0842 0.578 0.954 0.809 1.13 ukb-melanoma-gwas-catalog all 411.41 Aneurysm and dissection of heart Circulatory System Both 0.992 0.918 1.07 0.849 701 7010 FALSE 0.0710923097560473 -0.00757 0.0397 0.0647 0.111 0.559 1.07 0.858 1.33 0.0395 0.111 0.723 1.04 0.836 1.29 -0.0722 0.115 0.528 0.93 0.742 1.17 ukb-melanoma-gwas-catalog all 414 Other forms of chronic heart disease Circulatory System Both 0.977 0.931 1.03 0.352 1827 18270 FALSE 0.453457336521869 -0.0229 0.0246 0.0639 0.0683 0.349 1.07 0.932 1.22 -0.038 0.0699 0.587 0.963 0.839 1.1 -0.044 0.0702 0.531 0.957 0.834 1.1 ukb-melanoma-gwas-catalog all 414.2 ASCVD Circulatory System Both 1.02 0.798 1.3 0.864 72 720 FALSE 0.0634862575211067 0.0209 0.122 0.959 0.355 0.00697 2.61 1.31 5.51 0.296 0.389 0.447 1.34 0.616 3.02 0.358 0.391 0.359 1.43 0.654 3.23 ukb-melanoma-gwas-catalog all 415 Pulmonary heart disease Circulatory System Both 0.965 0.936 0.995 0.0219 4531 45310 TRUE 1.65955588515988 -0.0359 0.0157 -0.107 0.0436 0.0143 0.899 0.825 0.979 -0.0909 0.0434 0.0364 0.913 0.839 0.994 -0.138 0.044 0.00173 0.871 0.799 0.95 ukb-melanoma-gwas-catalog all 415.1 Acute pulmonary heart disease Circulatory System Both 1.06 0.833 1.34 0.646 75 750 FALSE 0.189767482004916 0.0549 0.12 -0.69 0.365 0.0585 0.502 0.233 1.02 -0.376 0.336 0.263 0.687 0.346 1.33 0.105 0.303 0.729 1.11 0.608 2.04 ukb-melanoma-gwas-catalog all 415.2 Chronic pulmonary heart disease Circulatory System Both 1 0.92 1.09 0.983 602 6020 FALSE 0.00744648216786438 0.00091 0.0427 0.096 0.119 0.42 1.1 0.871 1.39 -0.0402 0.123 0.743 0.961 0.754 1.22 0.0028 0.122 0.982 1 0.79 1.27 ukb-melanoma-gwas-catalog all 415.11 Pulmonary embolism and infarction, acute Circulatory System Both 1.06 0.833 1.34 0.646 75 750 FALSE 0.189767482004916 0.0549 0.12 -0.69 0.365 0.0585 0.502 0.233 1.02 -0.376 0.336 0.263 0.687 0.346 1.33 0.105 0.303 0.729 1.11 0.608 2.04 ukb-melanoma-gwas-catalog all 415.21 Primary pulmonary hypertension Circulatory System Both 1 0.911 1.11 0.933 447 4470 FALSE 0.0301183562535 0.00417 0.0495 0.176 0.14 0.208 1.19 0.906 1.57 0.0679 0.143 0.634 1.07 0.808 1.42 0.0604 0.143 0.673 1.06 0.802 1.41 ukb-melanoma-gwas-catalog all 416 Cardiomegaly Circulatory System Both 1 0.965 1.04 0.852 2686 26860 FALSE 0.0695604052332999 0.00379 0.0203 0.0346 0.0573 0.547 1.04 0.925 1.16 0.0512 0.0571 0.37 1.05 0.941 1.18 -0.0201 0.0581 0.73 0.98 0.874 1.1 ukb-melanoma-gwas-catalog all 418 Nonspecific chest pain Circulatory System Both 1.01 0.996 1.02 0.164 28677 270690 FALSE 0.785156151952302 0.00867 0.00623 0.00422 0.0177 0.811 1 0.97 1.04 -0.002 0.0177 0.91 0.998 0.964 1.03 0.0259 0.0176 0.142 1.03 0.991 1.06 ukb-melanoma-gwas-catalog all 418.1 Precordial pain Circulatory System Both 1.03 0.992 1.06 0.133 3567 35670 FALSE 0.876148359032914 0.0264 0.0176 0.0279 0.05 0.576 1.03 0.932 1.13 -0.0191 0.0506 0.706 0.981 0.888 1.08 0.0949 0.0495 0.0551 1.1 0.998 1.21 ukb-melanoma-gwas-catalog all 420 Carditis Circulatory System Both 1.07 1.02 1.11 0.00498 2146 21460 TRUE 2.30277065724028 0.0637 0.0227 0.104 0.0649 0.109 1.11 0.977 1.26 0.0489 0.0658 0.458 1.05 0.923 1.19 0.149 0.0645 0.0211 1.16 1.02 1.32 ukb-melanoma-gwas-catalog all 420.1 Myocarditis Circulatory System Both 1.11 0.923 1.33 0.269 127 1270 FALSE 0.570247719997592 0.102 0.0921 -0.0876 0.273 0.748 0.916 0.53 1.58 0.173 0.259 0.505 1.19 0.711 2 0.2 0.258 0.439 1.22 0.733 2.05 ukb-melanoma-gwas-catalog all 420.2 Pericarditis Circulatory System Both 1.03 0.978 1.09 0.235 1346 13460 FALSE 0.628932137728264 0.034 0.0286 0.186 0.0807 0.0209 1.2 1.03 1.41 0.0367 0.0835 0.66 1.04 0.881 1.22 0.11 0.0822 0.183 1.12 0.95 1.31 ukb-melanoma-gwas-catalog all 420.3 Endocarditis Circulatory System Both 1.13 1.04 1.22 0.0022 719 7190 TRUE 2.65757731917779 0.12 0.0392 -0.016 0.115 0.89 0.984 0.784 1.23 0.0904 0.113 0.423 1.09 0.877 1.37 0.232 0.11 0.0344 1.26 1.02 1.57 ukb-melanoma-gwas-catalog all 420.21 Acute pericarditis Circulatory System Both 0.981 0.854 1.13 0.778 224 2240 FALSE 0.109020403010311 -0.0197 0.0699 0.211 0.197 0.284 1.23 0.838 1.82 0.185 0.195 0.341 1.2 0.82 1.77 -0.122 0.208 0.558 0.885 0.585 1.34 ukb-melanoma-gwas-catalog all 420.22 Chronic pericarditis Circulatory System Both 1.03 0.851 1.26 0.735 113 1130 FALSE 0.133712660915805 0.0333 0.0983 0.162 0.276 0.557 1.18 0.68 2.05 0.0849 0.28 0.762 1.09 0.624 1.91 0.0613 0.286 0.83 1.06 0.601 1.88 ukb-melanoma-gwas-catalog all 425 Cardiomyopathy Circulatory System Both 1.03 0.974 1.09 0.283 1277 12770 FALSE 0.54821356447571 0.0315 0.0294 0.165 0.0833 0.0479 1.18 1 1.39 0.0638 0.0851 0.453 1.07 0.902 1.26 0.102 0.0846 0.229 1.11 0.938 1.31 ukb-melanoma-gwas-catalog all 425.1 Primary/intrinsic cardiomyopathies Circulatory System Both 1.04 0.98 1.1 0.196 1238 12380 FALSE 0.707743928643524 0.0386 0.0298 0.197 0.0847 0.0203 1.22 1.03 1.44 0.0879 0.0866 0.31 1.09 0.921 1.29 0.117 0.0864 0.177 1.12 0.949 1.33 ukb-melanoma-gwas-catalog all 425.8 Other cardiomyopathy Circulatory System Both 0.861 0.654 1.13 0.27 60 600 FALSE 0.568636235841013 -0.15 0.136 -0.536 0.366 0.143 0.585 0.274 1.2 -0.519 0.365 0.154 0.595 0.281 1.22 -0.483 0.36 0.18 0.617 0.296 1.25 ukb-melanoma-gwas-catalog all 425.11 Hypertrophic obstructive cardiomyopathy Circulatory System Both 1.03 0.857 1.23 0.783 132 1320 FALSE 0.106238237942057 0.0249 0.0905 0.14 0.265 0.596 1.15 0.68 1.96 0.444 0.25 0.0756 1.56 0.956 2.58 -0.0104 0.272 0.969 0.99 0.574 1.71 ukb-melanoma-gwas-catalog all 425.12 Other hypertrophic cardiomyopathy Circulatory System Both 0.875 0.745 1.03 0.103 164 1640 FALSE 0.987162775294828 -0.133 0.0816 -0.041 0.219 0.852 0.96 0.621 1.48 -0.208 0.227 0.361 0.812 0.516 1.27 -0.256 0.232 0.27 0.774 0.487 1.22 ukb-melanoma-gwas-catalog all 426 Cardiac conduction disorders Circulatory System Both 1.02 0.995 1.05 0.127 6937 69370 FALSE 0.896196279044043 0.0193 0.0126 0.00115 0.0359 0.974 1 0.933 1.07 0.0219 0.0358 0.54 1.02 0.953 1.1 0.0401 0.0357 0.262 1.04 0.97 1.12 ukb-melanoma-gwas-catalog all 426.2 Atrioventricular [AV] block Circulatory System Both 1.03 0.983 1.07 0.233 2126 21259 FALSE 0.632644078973981 0.0272 0.0228 0.0572 0.065 0.379 1.06 0.932 1.2 0.119 0.0643 0.0639 1.13 0.993 1.28 0.0241 0.0658 0.714 1.02 0.9 1.17 ukb-melanoma-gwas-catalog all 426.3 Bundle branch block Circulatory System Both 1.02 0.984 1.06 0.28 3344 33440 FALSE 0.552841968657781 0.0197 0.0182 0.066 0.0514 0.2 1.07 0.966 1.18 0.0285 0.0519 0.582 1.03 0.929 1.14 0.0456 0.0517 0.378 1.05 0.946 1.16 ukb-melanoma-gwas-catalog all 426.4 Anomalous atrioventricular excitation Circulatory System Both 0.957 0.836 1.1 0.523 233 2330 FALSE 0.281498311132726 -0.0438 0.0687 -0.195 0.192 0.308 0.822 0.562 1.2 -0.207 0.192 0.28 0.813 0.555 1.19 -0.0955 0.188 0.612 0.909 0.626 1.32 ukb-melanoma-gwas-catalog all 426.8 Other cardiac conduction disorders Circulatory System Both 1.05 0.805 1.37 0.711 60 600 FALSE 0.148130399270234 0.0492 0.133 0.727 0.385 0.0592 2.07 0.976 4.65 0.313 0.406 0.44 1.37 0.605 3.19 0.255 0.416 0.539 1.29 0.559 3.07 ukb-melanoma-gwas-catalog all 426.9 Cardiac pacemaker/device in situ Circulatory System Both 1.04 0.996 1.08 0.0788 2485 24848 FALSE 1.10347378251044 0.0371 0.0211 -0.0464 0.0605 0.443 0.955 0.848 1.07 0.0223 0.0597 0.708 1.02 0.91 1.15 0.0796 0.0591 0.178 1.08 0.964 1.22 ukb-melanoma-gwas-catalog all 426.21 First degree AV block Circulatory System Both 1.04 0.973 1.11 0.249 989 9890 FALSE 0.603800652904264 0.0385 0.0333 0.0698 0.0956 0.465 1.07 0.889 1.29 0.0574 0.0958 0.549 1.06 0.877 1.28 0.123 0.0946 0.193 1.13 0.939 1.36 ukb-melanoma-gwas-catalog all 426.23 Second degree AV block Circulatory System Both 1.03 0.933 1.13 0.579 453 4530 FALSE 0.237321436272564 0.0274 0.0493 -0.0189 0.14 0.892 0.981 0.745 1.29 -0.00988 0.14 0.944 0.99 0.752 1.3 0.0442 0.138 0.749 1.05 0.796 1.37 ukb-melanoma-gwas-catalog all 426.24 Atrioventricular block, complete Circulatory System Both 1.01 0.927 1.1 0.82 588 5871 FALSE 0.0861861476162833 0.00984 0.0433 0.067 0.124 0.588 1.07 0.839 1.36 0.259 0.12 0.0304 1.3 1.02 1.64 -0.102 0.129 0.431 0.903 0.7 1.16 ukb-melanoma-gwas-catalog all 426.25 Other heart block Circulatory System Both 1.07 0.898 1.28 0.429 132 1320 FALSE 0.367542707815276 0.0716 0.0906 0.403 0.259 0.119 1.5 0.901 2.52 0.155 0.274 0.57 1.17 0.678 2.02 0.243 0.268 0.366 1.27 0.75 2.19 ukb-melanoma-gwas-catalog all 426.31 Right bundle branch block Circulatory System Both 1.03 0.98 1.09 0.219 1496 14960 FALSE 0.659555885159882 0.0334 0.0272 0.0563 0.0764 0.462 1.06 0.911 1.23 -0.0124 0.0778 0.873 0.988 0.848 1.15 0.0349 0.077 0.65 1.04 0.89 1.2 ukb-melanoma-gwas-catalog all 426.32 Left bundle branch block Circulatory System Both 1.02 0.974 1.07 0.361 1753 17530 FALSE 0.442492798094342 0.0229 0.0251 0.12 0.0715 0.0931 1.13 0.98 1.3 0.0794 0.0721 0.271 1.08 0.94 1.25 0.103 0.0718 0.153 1.11 0.963 1.28 ukb-melanoma-gwas-catalog all 426.91 Cardiac pacemaker in situ Circulatory System Both 1.04 0.993 1.08 0.099 2281 22806 FALSE 1.00436480540245 0.0363 0.022 -0.0322 0.0629 0.609 0.968 0.856 1.1 0.016 0.0624 0.798 1.02 0.899 1.15 0.0685 0.0618 0.268 1.07 0.949 1.21 ukb-melanoma-gwas-catalog all 427 Cardiac dysrhythmias Circulatory System Both 1.02 1 1.03 0.0278 24341 206836 TRUE 1.55595520408192 0.015 0.00681 0.0363 0.0193 0.0601 1.04 0.998 1.08 0.0233 0.0194 0.228 1.02 0.985 1.06 0.0428 0.0194 0.027 1.04 1 1.08 ukb-melanoma-gwas-catalog all 427.1 Paroxysmal tachycardia, unspecified Circulatory System Both 1.01 0.977 1.05 0.488 3219 32190 FALSE 0.311580177997289 0.0129 0.0185 0.0321 0.0527 0.543 1.03 0.931 1.15 0.0712 0.0524 0.174 1.07 0.969 1.19 0.0263 0.053 0.62 1.03 0.925 1.14 ukb-melanoma-gwas-catalog all 427.2 Atrial fibrillation and flutter Circulatory System Both 1.01 0.993 1.03 0.266 14669 133702 FALSE 0.575118363368933 0.00971 0.00873 0.0273 0.0247 0.27 1.03 0.979 1.08 0.0172 0.0248 0.487 1.02 0.969 1.07 0.0278 0.0248 0.263 1.03 0.979 1.08 ukb-melanoma-gwas-catalog all 427.3 Other specified cardiac dysrhythmias Circulatory System Both 1.01 0.973 1.05 0.646 3234 32340 FALSE 0.189767482004916 0.00849 0.0185 0.0366 0.0522 0.483 1.04 0.936 1.15 -0.0234 0.0529 0.659 0.977 0.881 1.08 0.0579 0.0521 0.267 1.06 0.957 1.17 ukb-melanoma-gwas-catalog all 427.4 Cardiac arrest and ventricular fibrillation Circulatory System Both 1.03 0.968 1.09 0.371 1200 12000 FALSE 0.430626090384954 0.0272 0.0304 0.0744 0.0867 0.391 1.08 0.909 1.28 0.0939 0.0865 0.278 1.1 0.927 1.3 0.0879 0.0871 0.313 1.09 0.92 1.3 ukb-melanoma-gwas-catalog all 427.5 Arrhythmia (cardiac) NOS Circulatory System Both 1.04 0.971 1.11 0.272 957 9570 FALSE 0.565431095965801 0.0373 0.0339 -0.0576 0.0978 0.556 0.944 0.779 1.14 0.0329 0.096 0.732 1.03 0.856 1.25 0.0854 0.0951 0.369 1.09 0.904 1.31 ukb-melanoma-gwas-catalog all 427.6 Premature beats Circulatory System Both 1.13 1.03 1.23 0.00835 536 5360 TRUE 2.0783135245164 0.12 0.0454 0.0378 0.133 0.776 1.04 0.799 1.35 0.0727 0.132 0.582 1.08 0.829 1.4 0.3 0.127 0.0181 1.35 1.05 1.73 ukb-melanoma-gwas-catalog all 427.7 Tachycardia NOS Circulatory System Both 1.01 0.962 1.05 0.798 2191 21899 FALSE 0.0979971086492705 0.00575 0.0225 -0.012 0.0639 0.851 0.988 0.872 1.12 0.0663 0.0629 0.292 1.07 0.945 1.21 -0.0129 0.0641 0.84 0.987 0.871 1.12 ukb-melanoma-gwas-catalog all 427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System Both 0.938 0.846 1.04 0.224 403 4030 FALSE 0.649751981665837 -0.0637 0.0524 0.0687 0.142 0.629 1.07 0.81 1.42 -0.17 0.151 0.258 0.843 0.626 1.13 -0.0866 0.148 0.559 0.917 0.684 1.23 ukb-melanoma-gwas-catalog all 427.9 Palpitations Circulatory System Both 1.06 1.02 1.09 0.00124 3816 38155 TRUE 2.90657831483776 0.0549 0.017 0.068 0.0492 0.167 1.07 0.972 1.18 0.0778 0.0491 0.113 1.08 0.982 1.19 0.173 0.0482 0.000341 1.19 1.08 1.31 ukb-melanoma-gwas-catalog all 427.11 Paroxysmal supraventricular tachycardia Circulatory System Both 1.02 0.98 1.07 0.312 2353 23530 FALSE 0.505845405981557 0.0219 0.0217 0.0136 0.0619 0.826 1.01 0.898 1.14 0.0792 0.0611 0.195 1.08 0.96 1.22 0.0381 0.0618 0.538 1.04 0.92 1.17 ukb-melanoma-gwas-catalog all 427.12 Paroxysmal ventricular tachycardia Circulatory System Both 1 0.934 1.07 0.991 938 9380 FALSE 0.00392634551472468 -0.000384 0.0343 0.0187 0.0975 0.848 1.02 0.841 1.23 0.091 0.096 0.343 1.1 0.907 1.32 -0.0132 0.0987 0.894 0.987 0.813 1.2 ukb-melanoma-gwas-catalog all 427.41 Ventricular fibrillation and flutter Circulatory System Both 1.02 0.915 1.14 0.693 344 3440 FALSE 0.159266765388193 0.0222 0.0564 -0.0457 0.161 0.777 0.955 0.694 1.31 -0.0211 0.161 0.896 0.979 0.713 1.34 0.109 0.157 0.487 1.11 0.819 1.52 ukb-melanoma-gwas-catalog all 427.42 Cardiac arrest Circulatory System Both 1.03 0.965 1.1 0.377 991 9910 FALSE 0.423658649794207 0.0295 0.0334 0.03 0.0955 0.754 1.03 0.854 1.24 0.102 0.0942 0.281 1.11 0.92 1.33 0.0517 0.0961 0.591 1.05 0.872 1.27 ukb-melanoma-gwas-catalog all 427.61 Supraventricular premature beats Circulatory System Both 1.11 0.918 1.34 0.274 117 1169 FALSE 0.562249437179612 0.105 0.096 -0.0489 0.266 0.854 0.952 0.56 1.62 -0.564 0.303 0.0625 0.569 0.305 1.03 0.224 0.252 0.375 1.25 0.761 2.07 ukb-melanoma-gwas-catalog all 428 Congestive heart failure; nonhypertensive Circulatory System Both 1.01 0.984 1.04 0.403 5621 56168 FALSE 0.394694953858891 0.0117 0.014 0.0607 0.0397 0.127 1.06 0.983 1.15 0.0629 0.0398 0.114 1.06 0.985 1.15 0.0188 0.0403 0.64 1.02 0.942 1.1 ukb-melanoma-gwas-catalog all 428.1 Congestive heart failure (CHF) NOS Circulatory System Both 1 0.957 1.05 0.964 2106 21052 FALSE 0.0159229660971692 0.00103 0.0229 0.0421 0.0641 0.511 1.04 0.92 1.18 -0.0127 0.065 0.844 0.987 0.869 1.12 -0.0195 0.0652 0.766 0.981 0.863 1.11 ukb-melanoma-gwas-catalog all 428.2 Heart failure NOS Circulatory System Both 1.01 0.981 1.04 0.447 4457 44528 FALSE 0.349692476868063 0.012 0.0158 0.0722 0.0447 0.106 1.07 0.985 1.17 0.0779 0.0446 0.081 1.08 0.99 1.18 0.0203 0.0454 0.654 1.02 0.934 1.12 ukb-melanoma-gwas-catalog all 429 Ill-defined descriptions and complications of heart disease Circulatory System Both 1.02 0.942 1.1 0.669 734 7340 FALSE 0.174573882232177 0.0165 0.0388 0.0557 0.108 0.605 1.06 0.856 1.31 -0.136 0.113 0.227 0.873 0.699 1.09 0.0533 0.108 0.622 1.05 0.853 1.31 ukb-melanoma-gwas-catalog all 429.2 Abnormal function study of cardiovascular system Circulatory System Both 1.04 0.95 1.14 0.402 524 5240 FALSE 0.39577394691553 0.0384 0.0458 0.0598 0.13 0.644 1.06 0.823 1.37 -0.065 0.133 0.626 0.937 0.72 1.22 0.149 0.128 0.245 1.16 0.903 1.49 ukb-melanoma-gwas-catalog all 429.3 Symptoms involving cardiovascular system Circulatory System Both 0.969 0.836 1.12 0.669 198 1980 FALSE 0.174573882232177 -0.0318 0.0745 0.00713 0.2 0.972 1.01 0.678 1.5 -0.25 0.215 0.245 0.779 0.507 1.19 -0.136 0.207 0.511 0.873 0.578 1.31 ukb-melanoma-gwas-catalog all 430 Intracranial hemorrhage Circulatory System Both 0.994 0.948 1.04 0.793 1908 19080 FALSE 0.100726812682396 -0.00633 0.0241 -0.0515 0.0676 0.446 0.95 0.832 1.08 -0.0701 0.068 0.303 0.932 0.816 1.07 -0.026 0.0676 0.7 0.974 0.853 1.11 ukb-melanoma-gwas-catalog all 430.1 Subarachnoid hemorrhage Circulatory System Both 0.955 0.89 1.03 0.206 855 8550 FALSE 0.686132779630847 -0.0455 0.036 -0.0937 0.0993 0.345 0.911 0.749 1.11 -0.173 0.101 0.0881 0.841 0.689 1.03 -0.11 0.1 0.272 0.896 0.735 1.09 ukb-melanoma-gwas-catalog all 430.2 Intracerebral hemorrhage Circulatory System Both 1.04 0.969 1.12 0.255 769 7690 FALSE 0.593459819566045 0.0431 0.0379 0.0181 0.109 0.868 1.02 0.823 1.26 0.0856 0.108 0.427 1.09 0.882 1.35 0.0922 0.107 0.39 1.1 0.888 1.35 ukb-melanoma-gwas-catalog all 430.3 Subdural hemorrhage Circulatory System Both 0.943 0.83 1.07 0.363 267 2670 FALSE 0.440093374963888 -0.0586 0.0645 -0.0243 0.176 0.89 0.976 0.689 1.38 -0.139 0.182 0.445 0.87 0.606 1.25 -0.0913 0.179 0.611 0.913 0.64 1.3 ukb-melanoma-gwas-catalog all 433 Cerebrovascular disease Circulatory System Both 1.02 1 1.04 0.0513 8804 87981 FALSE 1.28988263488818 0.0219 0.0112 0.0151 0.0318 0.634 1.02 0.954 1.08 0.0186 0.0318 0.56 1.02 0.957 1.08 0.0441 0.0318 0.165 1.05 0.982 1.11 ukb-melanoma-gwas-catalog all 433.1 Occlusion and stenosis of precerebral arteries Circulatory System Both 1.06 0.996 1.12 0.0689 1187 11848 FALSE 1.16178077809237 0.0555 0.0305 0.0536 0.0881 0.543 1.06 0.888 1.25 0.0384 0.0883 0.664 1.04 0.874 1.24 0.195 0.0857 0.0227 1.22 1.03 1.44 ukb-melanoma-gwas-catalog all 433.2 Occlusion of cerebral arteries Circulatory System Both 1.02 0.988 1.05 0.218 4244 42423 FALSE 0.661543506395395 0.0199 0.0162 -0.0203 0.0461 0.659 0.98 0.895 1.07 0.0264 0.0456 0.563 1.03 0.939 1.12 0.0454 0.0456 0.319 1.05 0.957 1.14 ukb-melanoma-gwas-catalog all 433.3 Cerebral ischemia Circulatory System Both 1.05 1.01 1.09 0.0229 2920 29192 TRUE 1.64016451766011 0.0442 0.0194 0.0491 0.0551 0.373 1.05 0.943 1.17 -0.0147 0.056 0.793 0.985 0.883 1.1 0.0921 0.0548 0.0928 1.1 0.985 1.22 ukb-melanoma-gwas-catalog all 433.5 Cerebral aneurysm Circulatory System Both 1.01 0.913 1.12 0.806 391 3909 FALSE 0.0936649581949093 0.013 0.053 0.0318 0.153 0.836 1.03 0.763 1.4 0.199 0.148 0.18 1.22 0.912 1.64 0.0768 0.153 0.616 1.08 0.799 1.46 ukb-melanoma-gwas-catalog all 433.8 Late effects of cerebrovascular disease Circulatory System Both 1 0.943 1.06 0.989 1270 12693 FALSE 0.0048037084028206 -0.000407 0.0295 0.0374 0.0824 0.65 1.04 0.883 1.22 -0.00832 0.0832 0.92 0.992 0.842 1.17 -0.0599 0.0844 0.478 0.942 0.798 1.11 ukb-melanoma-gwas-catalog all 433.12 Cerebral atherosclerosis Circulatory System Both 1.06 0.926 1.22 0.388 227 2270 FALSE 0.411168274405793 0.0599 0.0693 -0.0214 0.2 0.915 0.979 0.659 1.45 -0.0934 0.203 0.645 0.911 0.609 1.36 0.226 0.19 0.234 1.25 0.863 1.83 ukb-melanoma-gwas-catalog all 433.21 Cerebral artery occlusion, with cerebral infarction Circulatory System Both 1.02 0.968 1.07 0.501 1685 16840 FALSE 0.300162274132754 0.0172 0.0256 -0.11 0.073 0.131 0.896 0.776 1.03 -0.0551 0.072 0.444 0.946 0.822 1.09 0.0179 0.0711 0.801 1.02 0.886 1.17 ukb-melanoma-gwas-catalog all 433.31 Transient cerebral ischemia Circulatory System Both 1.02 0.98 1.07 0.292 2132 21312 FALSE 0.534617148551582 0.024 0.0228 0.0238 0.0638 0.709 1.02 0.904 1.16 -0.0836 0.0655 0.202 0.92 0.809 1.05 0.0474 0.0638 0.457 1.05 0.925 1.19 ukb-melanoma-gwas-catalog all 440 Atherosclerosis Circulatory System Both 1.04 0.982 1.1 0.192 1390 13890 FALSE 0.71669877129645 0.0368 0.0282 0.0839 0.0809 0.3 1.09 0.928 1.27 0.0703 0.0812 0.386 1.07 0.915 1.26 0.137 0.0802 0.0879 1.15 0.98 1.34 ukb-melanoma-gwas-catalog all 440.1 Atherosclerosis of renal artery Circulatory System Both 1.18 0.974 1.43 0.0866 113 1128 FALSE 1.06248210798265 0.166 0.0967 -0.223 0.298 0.454 0.8 0.438 1.45 0.215 0.274 0.434 1.24 0.721 2.15 0.203 0.27 0.452 1.23 0.718 2.11 ukb-melanoma-gwas-catalog all 440.2 Atherosclerosis of the extremities Circulatory System Both 1.06 0.986 1.14 0.114 811 8105 FALSE 0.943095148663527 0.0582 0.0368 0.237 0.105 0.0234 1.27 1.03 1.56 0.0525 0.109 0.63 1.05 0.851 1.31 0.2 0.106 0.059 1.22 0.992 1.5 ukb-melanoma-gwas-catalog all 440.9 Atherosclerosis of aorta Circulatory System Both 1.05 0.931 1.19 0.42 286 2860 FALSE 0.3767507096021 0.0498 0.0618 0.311 0.179 0.0816 1.36 0.962 1.95 0.183 0.183 0.319 1.2 0.837 1.73 0.255 0.181 0.159 1.29 0.904 1.85 ukb-melanoma-gwas-catalog all 441 Vascular insufficiency of intestine Circulatory System Both 1.05 0.971 1.15 0.205 620 6200 FALSE 0.688246138944246 0.0535 0.0422 -0.0304 0.12 0.799 0.97 0.767 1.23 -0.0706 0.121 0.56 0.932 0.734 1.18 0.0929 0.117 0.427 1.1 0.872 1.38 ukb-melanoma-gwas-catalog all 441.1 Acute vascular insufficiency of intestine Circulatory System Both 1 0.887 1.13 0.962 283 2830 FALSE 0.0168249279621871 0.00302 0.0626 0.0583 0.171 0.733 1.06 0.756 1.49 -0.232 0.184 0.206 0.793 0.55 1.14 0.0331 0.173 0.848 1.03 0.734 1.46 ukb-melanoma-gwas-catalog all 442 Other aneurysm Circulatory System Both 0.996 0.95 1.04 0.852 1907 19057 FALSE 0.0695604052332999 -0.00449 0.0241 0.0182 0.0674 0.788 1.02 0.892 1.16 -0.0342 0.0683 0.616 0.966 0.845 1.1 -0.00453 0.0681 0.947 0.995 0.871 1.14 ukb-melanoma-gwas-catalog all 442.1 Aortic aneurysm Circulatory System Both 0.986 0.934 1.04 0.598 1468 14679 FALSE 0.223298816011589 -0.0145 0.0275 -0.0497 0.0769 0.518 0.951 0.818 1.11 -0.0509 0.0769 0.508 0.95 0.817 1.11 -0.0555 0.0774 0.473 0.946 0.813 1.1 ukb-melanoma-gwas-catalog all 442.2 Aneurysm of iliac artery Circulatory System Both 1.15 0.941 1.41 0.166 102 1020 FALSE 0.779891911959945 0.142 0.103 0.215 0.311 0.489 1.24 0.668 2.33 0.258 0.311 0.406 1.29 0.697 2.43 0.591 0.295 0.0448 1.81 1.02 3.3 ukb-melanoma-gwas-catalog all 442.3 Aneurysm of artery of lower extremity Circulatory System Both 1.06 0.901 1.24 0.497 170 1700 FALSE 0.303643611266668 0.0545 0.0802 0.443 0.231 0.0548 1.56 0.991 2.48 0.348 0.234 0.137 1.42 0.894 2.26 0.221 0.244 0.365 1.25 0.769 2.03 ukb-melanoma-gwas-catalog all 442.4 Arterial dissection Circulatory System Both 1.15 0.876 1.52 0.299 55 550 FALSE 0.52432881167557 0.143 0.137 -0.1 0.43 0.816 0.905 0.372 2.17 0.15 0.394 0.703 1.16 0.526 2.6 0.429 0.374 0.251 1.54 0.735 3.32 ukb-melanoma-gwas-catalog all 442.8 Aneurysm of other specified artery Circulatory System Both 0.962 0.832 1.11 0.592 203 2030 FALSE 0.22767829327708 -0.0393 0.0733 0.336 0.197 0.0887 1.4 0.951 2.07 -0.372 0.23 0.107 0.69 0.434 1.08 0.128 0.206 0.534 1.14 0.757 1.71 ukb-melanoma-gwas-catalog all 442.11 Abdominal aortic aneurysm Circulatory System Both 1.03 0.959 1.1 0.453 939 9383 FALSE 0.343901797987168 0.0257 0.0343 0.00509 0.0975 0.958 1.01 0.83 1.22 -0.0284 0.0983 0.773 0.972 0.801 1.18 0.0895 0.096 0.351 1.09 0.906 1.32 ukb-melanoma-gwas-catalog all 443 Peripheral vascular disease Circulatory System Both 1.03 0.996 1.06 0.085 3950 39492 FALSE 1.07058107428571 0.0288 0.0167 0.00128 0.0477 0.979 1 0.912 1.1 0.0256 0.0475 0.591 1.03 0.935 1.13 0.0613 0.0473 0.195 1.06 0.969 1.17 ukb-melanoma-gwas-catalog all 443.1 Raynaud's syndrome Circulatory System Both 1.06 0.999 1.13 0.054 1145 11450 FALSE 1.26760624017703 0.0598 0.031 -0.111 0.0905 0.22 0.895 0.749 1.07 0.0581 0.0873 0.506 1.06 0.893 1.26 0.104 0.0867 0.231 1.11 0.936 1.32 ukb-melanoma-gwas-catalog all 443.7 Peripheral angiopathy in diseases classified elsewhere Circulatory System Both 1.04 0.94 1.16 0.418 390 3900 FALSE 0.378823718224965 0.043 0.0531 -0.0329 0.149 0.825 0.968 0.722 1.3 -0.0866 0.15 0.565 0.917 0.681 1.23 -0.0145 0.149 0.922 0.986 0.735 1.32 ukb-melanoma-gwas-catalog all 443.9 Peripheral vascular disease, unspecified Circulatory System Both 1.01 0.971 1.05 0.585 2591 25902 FALSE 0.23284413391782 0.0113 0.0207 0.0193 0.0585 0.741 1.02 0.909 1.14 0.0104 0.0587 0.86 1.01 0.901 1.13 0.0338 0.0586 0.564 1.03 0.922 1.16 ukb-melanoma-gwas-catalog all 444 Arterial embolism and thrombosis Circulatory System Both 1.04 0.97 1.11 0.276 930 9300 FALSE 0.559090917934782 0.0375 0.0344 0.0492 0.0977 0.615 1.05 0.867 1.27 -0.0323 0.0996 0.746 0.968 0.796 1.18 0.12 0.0964 0.215 1.13 0.933 1.36 ukb-melanoma-gwas-catalog all 444.1 Arterial embolism and thrombosis of lower extremity artery Circulatory System Both 1.04 0.953 1.13 0.38 556 5560 FALSE 0.42021640338319 0.0389 0.0444 0.0239 0.126 0.849 1.02 0.8 1.31 -0.0194 0.128 0.879 0.981 0.763 1.26 0.0819 0.124 0.511 1.09 0.85 1.39 ukb-melanoma-gwas-catalog all 446 Polyarteritis nodosa and allied conditions Circulatory System Both 1.01 0.941 1.09 0.771 829 8290 FALSE 0.112945621949043 0.0106 0.0365 -0.0236 0.103 0.82 0.977 0.797 1.2 -0.0688 0.104 0.51 0.934 0.76 1.15 0.0531 0.102 0.602 1.05 0.864 1.29 ukb-melanoma-gwas-catalog all 446.4 Wegener's granulomatosis Circulatory System Both 0.965 0.829 1.12 0.638 187 1870 FALSE 0.195179321278838 -0.0361 0.0768 -0.116 0.213 0.587 0.891 0.583 1.36 -0.144 0.215 0.501 0.866 0.565 1.32 -0.153 0.214 0.474 0.858 0.561 1.31 ukb-melanoma-gwas-catalog all 446.5 Giant cell arteritis Circulatory System Both 1.03 0.924 1.14 0.62 386 3860 FALSE 0.207608310501746 0.0265 0.0535 -0.0541 0.152 0.722 0.947 0.701 1.28 -0.0505 0.152 0.74 0.951 0.704 1.28 0.0746 0.148 0.615 1.08 0.805 1.44 ukb-melanoma-gwas-catalog all 446.9 Arteritis NOS Circulatory System Both 1.04 0.909 1.18 0.582 240 2400 FALSE 0.235077015350112 0.037 0.0673 -0.25 0.193 0.196 0.779 0.53 1.14 -0.318 0.196 0.105 0.727 0.491 1.07 0.118 0.177 0.503 1.13 0.795 1.6 ukb-melanoma-gwas-catalog all 447 Other disorders of arteries and arterioles Circulatory System Both 1 0.949 1.06 0.873 1336 13360 FALSE 0.0589857562944303 0.00461 0.0288 -0.0199 0.0819 0.808 0.98 0.835 1.15 0.0535 0.0807 0.507 1.05 0.901 1.24 0.0113 0.0817 0.89 1.01 0.861 1.19 ukb-melanoma-gwas-catalog all 447.1 Stricture of artery Circulatory System Both 1.05 0.981 1.13 0.156 873 8730 FALSE 0.806875401645538 0.0504 0.0356 0.1 0.102 0.327 1.11 0.904 1.35 0.1 0.102 0.328 1.11 0.904 1.35 0.156 0.101 0.125 1.17 0.958 1.43 ukb-melanoma-gwas-catalog all 448 Disease of capillaries Circulatory System Both 1.09 0.916 1.3 0.33 142 1420 FALSE 0.481486060122112 0.0853 0.0877 0.0619 0.259 0.811 1.06 0.635 1.79 0.382 0.244 0.118 1.47 0.908 2.39 0.146 0.258 0.572 1.16 0.694 1.94 ukb-melanoma-gwas-catalog all 450 Noninfectious disorders of lymphatic channels Circulatory System Both 1.02 0.945 1.1 0.592 705 7050 FALSE 0.22767829327708 0.0212 0.0395 0.151 0.112 0.179 1.16 0.933 1.45 0.041 0.115 0.721 1.04 0.831 1.31 0.121 0.113 0.282 1.13 0.905 1.41 ukb-melanoma-gwas-catalog all 451 Phlebitis and thrombophlebitis Circulatory System Both 0.98 0.949 1.01 0.222 4020 40200 FALSE 0.653647025549361 -0.0203 0.0166 0.0786 0.0463 0.0895 1.08 0.988 1.18 0.0362 0.0468 0.439 1.04 0.946 1.14 -0.0618 0.048 0.197 0.94 0.856 1.03 ukb-melanoma-gwas-catalog all 451.2 Phlebitis and thrombophlebitis of lower extremities Circulatory System Both 0.974 0.941 1.01 0.121 3707 37070 FALSE 0.91721462968355 -0.0268 0.0173 0.0894 0.048 0.0627 1.09 0.995 1.2 0.0208 0.0488 0.671 1.02 0.928 1.12 -0.0733 0.05 0.142 0.929 0.842 1.02 ukb-melanoma-gwas-catalog all 452 Other venous embolism and thrombosis Circulatory System Both 1.02 0.932 1.11 0.705 566 5660 FALSE 0.151810883008601 0.0167 0.0442 0.0122 0.125 0.922 1.01 0.791 1.3 -0.0278 0.127 0.826 0.973 0.758 1.25 0.106 0.123 0.39 1.11 0.873 1.42 ukb-melanoma-gwas-catalog all 454 Varicose veins Circulatory System Both 0.982 0.964 1 0.0614 12019 120183 FALSE 1.21183162885883 -0.018 0.00961 -0.0168 0.027 0.533 0.983 0.933 1.04 -0.00739 0.0269 0.784 0.993 0.942 1.05 -0.051 0.0273 0.0616 0.95 0.901 1 ukb-melanoma-gwas-catalog all 454.1 Varicose veins of lower extremity Circulatory System Both 0.981 0.963 1 0.0539 11549 115483 FALSE 1.26841123481326 -0.0189 0.0098 -0.0162 0.0275 0.556 0.984 0.932 1.04 -0.00675 0.0275 0.806 0.993 0.941 1.05 -0.0519 0.0278 0.0625 0.949 0.899 1 ukb-melanoma-gwas-catalog all 454.11 Varicose veins of lower extremity, symptomtic Circulatory System Both 0.982 0.904 1.07 0.659 626 6257 FALSE 0.18111458540599 -0.0185 0.042 0.0133 0.119 0.911 1.01 0.802 1.28 0.198 0.115 0.0849 1.22 0.973 1.53 -0.153 0.124 0.218 0.858 0.672 1.09 ukb-melanoma-gwas-catalog all 455 Hemorrhoids Circulatory System Both 0.996 0.983 1.01 0.604 23500 234947 FALSE 0.218963061378868 -0.00356 0.00687 -0.00623 0.0194 0.748 0.994 0.957 1.03 0.00305 0.0193 0.875 1 0.966 1.04 -0.0184 0.0195 0.344 0.982 0.945 1.02 ukb-melanoma-gwas-catalog all 456 Chronic venous insufficiency [CVI] Circulatory System Both 0.934 0.802 1.09 0.37 188 1880 FALSE 0.431798275933005 -0.0686 0.0766 0.0395 0.216 0.855 1.04 0.679 1.6 0.173 0.212 0.415 1.19 0.783 1.81 -0.0622 0.222 0.779 0.94 0.605 1.46 ukb-melanoma-gwas-catalog all 457 Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin Circulatory System Both 0.872 0.706 1.07 0.195 97 966 FALSE 0.709965388637482 -0.137 0.106 -0.572 0.295 0.0529 0.565 0.309 1.01 -0.416 0.284 0.142 0.66 0.371 1.15 -0.319 0.281 0.257 0.727 0.412 1.26 ukb-melanoma-gwas-catalog all 458 Hypotension Circulatory System Both 1.02 0.992 1.05 0.171 5801 58010 FALSE 0.767003889607846 0.0189 0.0138 0.0418 0.0392 0.287 1.04 0.966 1.13 0.0311 0.0393 0.429 1.03 0.955 1.11 0.0614 0.0392 0.117 1.06 0.985 1.15 ukb-melanoma-gwas-catalog all 458.1 Orthostatic hypotension Circulatory System Both 1.08 1.02 1.14 0.00932 1339 13390 TRUE 2.03058408764602 0.0745 0.0286 0.034 0.0839 0.685 1.03 0.878 1.22 0.161 0.0817 0.0484 1.18 1 1.38 0.162 0.0818 0.0479 1.18 1 1.38 ukb-melanoma-gwas-catalog all 458.2 Iatrogenic hypotension Circulatory System Both 1.19 1.04 1.36 0.0104 234 2340 TRUE 1.98296666070122 0.175 0.0683 0.153 0.199 0.441 1.17 0.787 1.73 -0.0647 0.21 0.758 0.937 0.618 1.42 0.454 0.19 0.0169 1.57 1.09 2.3 ukb-melanoma-gwas-catalog all 458.9 Hypotension NOS Circulatory System Both 1 0.966 1.04 0.998 3502 35020 FALSE 0.000869458712628891 5.15e-05 0.0178 0.0428 0.05 0.393 1.04 0.946 1.15 -0.00764 0.0507 0.88 0.992 0.899 1.1 0.0352 0.0503 0.484 1.04 0.939 1.14 ukb-melanoma-gwas-catalog all 459 Other disorders of circulatory system Circulatory System Both 1.01 0.996 1.03 0.157 16386 161616 FALSE 0.804100347590766 0.0116 0.00822 0.011 0.0233 0.636 1.01 0.966 1.06 0.0171 0.0233 0.463 1.02 0.972 1.06 0.0313 0.0233 0.18 1.03 0.986 1.08 ukb-melanoma-gwas-catalog all 459.1 Hemorrhage NOS Circulatory System Both 0.95 0.799 1.13 0.561 142 1420 FALSE 0.251037138743839 -0.0509 0.0876 0.204 0.239 0.394 1.23 0.765 1.98 0.132 0.243 0.587 1.14 0.705 1.85 -0.193 0.265 0.465 0.824 0.484 1.39 ukb-melanoma-gwas-catalog all 459.9 Circulatory disease NEC Circulatory System Both 1.01 0.997 1.03 0.124 16173 159853 FALSE 0.906578314837765 0.0127 0.00828 0.0116 0.0235 0.622 1.01 0.966 1.06 0.0163 0.0235 0.488 1.02 0.971 1.06 0.0339 0.0234 0.148 1.03 0.988 1.08 ukb-melanoma-gwas-catalog all 464 Acute sinusitis Respiratory Both 0.937 0.809 1.09 0.386 196 1960 FALSE 0.413412695328245 -0.0647 0.0747 -0.39 0.214 0.0685 0.677 0.441 1.03 -0.0874 0.198 0.659 0.916 0.619 1.35 -0.223 0.206 0.279 0.8 0.531 1.2 ukb-melanoma-gwas-catalog all 465 Acute upper respiratory infections of multiple or unspecified sites Respiratory Both 0.987 0.946 1.03 0.553 2332 23320 FALSE 0.257274868695302 -0.0129 0.0218 -0.0678 0.062 0.274 0.934 0.827 1.06 0.0683 0.0601 0.256 1.07 0.952 1.2 -0.0818 0.0623 0.189 0.921 0.815 1.04 ukb-melanoma-gwas-catalog all 465.2 Acute pharyngitis Respiratory Both 1 0.936 1.08 0.905 868 8680 FALSE 0.0433514207947967 0.00428 0.0357 -0.109 0.102 0.287 0.897 0.734 1.1 0.0671 0.098 0.493 1.07 0.882 1.3 -0.0695 0.101 0.492 0.933 0.764 1.14 ukb-melanoma-gwas-catalog all 465.4 Acute laryngitis and tracheitis Respiratory Both 0.999 0.85 1.17 0.991 166 1660 FALSE 0.00392634551472468 -0.000955 0.0816 0.28 0.23 0.224 1.32 0.841 2.1 0.303 0.23 0.188 1.35 0.862 2.15 -0.0361 0.249 0.885 0.965 0.587 1.58 ukb-melanoma-gwas-catalog all 470 Septal Deviations/Turbinate Hypertrophy Respiratory Both 1.01 0.981 1.04 0.488 4909 49081 FALSE 0.311580177997289 0.0104 0.015 -0.000689 0.0425 0.987 0.999 0.919 1.09 -0.0333 0.0429 0.438 0.967 0.889 1.05 0.0553 0.0422 0.189 1.06 0.973 1.15 ukb-melanoma-gwas-catalog all 471 Nasal polyps Respiratory Both 0.999 0.964 1.04 0.954 3301 33009 FALSE 0.0204516252959049 -0.00106 0.0183 -0.0154 0.0521 0.767 0.985 0.889 1.09 0.0575 0.0514 0.263 1.06 0.958 1.17 0.00815 0.052 0.876 1.01 0.91 1.12 ukb-melanoma-gwas-catalog all 472 Chronic pharyngitis and nasopharyngitis Respiratory Both 1.05 0.984 1.12 0.137 963 9630 FALSE 0.863279432843593 0.0504 0.0338 -0.0999 0.0983 0.31 0.905 0.746 1.1 0.000409 0.0962 0.997 1 0.828 1.21 0.139 0.0934 0.136 1.15 0.957 1.38 ukb-melanoma-gwas-catalog all 473 Diseases of the larynx and vocal cords Respiratory Both 1.03 0.992 1.08 0.113 2623 26230 FALSE 0.94692155651658 0.0326 0.0205 0.0534 0.0585 0.361 1.05 0.941 1.18 0.0343 0.0588 0.559 1.03 0.922 1.16 0.0933 0.0582 0.109 1.1 0.979 1.23 ukb-melanoma-gwas-catalog all 473.1 Chronic laryngitis Respiratory Both 0.959 0.783 1.17 0.684 104 1040 FALSE 0.164943898279884 -0.0415 0.102 -0.414 0.302 0.17 0.661 0.357 1.2 0.205 0.261 0.431 1.23 0.734 2.07 -0.371 0.297 0.212 0.69 0.377 1.24 ukb-melanoma-gwas-catalog all 473.3 Paralysis/spasm of vocal cords or larynx Respiratory Both 0.99 0.871 1.12 0.872 265 2650 FALSE 0.0594835150674328 -0.0103 0.0645 -0.0549 0.181 0.762 0.947 0.661 1.35 -0.0695 0.182 0.703 0.933 0.65 1.34 0.0483 0.179 0.787 1.05 0.737 1.5 ukb-melanoma-gwas-catalog all 473.4 Voice disturbance Respiratory Both 1.08 1.01 1.15 0.0205 1083 10830 TRUE 1.68824613894425 0.074 0.0319 0.0907 0.0931 0.33 1.09 0.912 1.31 0.194 0.0913 0.0338 1.21 1.01 1.45 0.17 0.0917 0.0633 1.19 0.991 1.42 ukb-melanoma-gwas-catalog all 474 Acute and chronic tonsillitis Respiratory Both 0.986 0.942 1.03 0.55 2008 20072 FALSE 0.259637310505756 -0.014 0.0235 -0.0369 0.0659 0.576 0.964 0.847 1.1 -0.0502 0.0662 0.448 0.951 0.835 1.08 -0.0285 0.0662 0.667 0.972 0.853 1.11 ukb-melanoma-gwas-catalog all 474.1 Acute tonsillitis Respiratory Both 0.958 0.882 1.04 0.318 613 6130 FALSE 0.497572880015567 -0.0425 0.0425 -0.155 0.119 0.192 0.856 0.678 1.08 -0.0699 0.116 0.548 0.932 0.742 1.17 -0.162 0.12 0.178 0.851 0.672 1.08 ukb-melanoma-gwas-catalog all 474.2 Chronic tonsillitis and adenoiditis Respiratory Both 0.996 0.937 1.06 0.902 1124 11232 FALSE 0.0447934624580583 -0.00386 0.0314 0.0164 0.0885 0.853 1.02 0.854 1.21 0.0224 0.0886 0.8 1.02 0.859 1.22 0.0026 0.0893 0.977 1 0.841 1.19 ukb-melanoma-gwas-catalog all 475 Chronic sinusitis Respiratory Both 0.993 0.953 1.03 0.717 2596 25951 FALSE 0.1444808443322 -0.0075 0.0207 -0.00992 0.0586 0.866 0.99 0.883 1.11 0.0404 0.058 0.486 1.04 0.929 1.17 0.000978 0.0587 0.987 1 0.892 1.12 ukb-melanoma-gwas-catalog all 476 Allergic rhinitis Respiratory Both 1.01 0.952 1.08 0.657 1059 10590 FALSE 0.182434630440219 0.0143 0.0323 -0.0875 0.0919 0.341 0.916 0.765 1.1 0.0135 0.0897 0.88 1.01 0.85 1.21 -0.0298 0.091 0.744 0.971 0.812 1.16 ukb-melanoma-gwas-catalog all 477 Epistaxis or throat hemorrhage Respiratory Both 0.989 0.949 1.03 0.608 2452 24509 FALSE 0.216096420727265 -0.0109 0.0212 -0.0903 0.0601 0.133 0.914 0.812 1.03 -0.0174 0.0592 0.768 0.983 0.875 1.1 -0.0591 0.0598 0.322 0.943 0.838 1.06 ukb-melanoma-gwas-catalog all 478 Throat pain Respiratory Both 1.1 0.986 1.22 0.0876 379 3790 FALSE 1.05749589383192 0.0915 0.0536 0.307 0.162 0.0579 1.36 0.99 1.88 0.495 0.157 0.00165 1.64 1.21 2.24 0.289 0.162 0.0748 1.34 0.971 1.84 ukb-melanoma-gwas-catalog all 479 Other upper respiratory disease Respiratory Both 1.04 1.01 1.07 0.0152 4089 40884 TRUE 1.81815641205523 0.0399 0.0165 0.0633 0.0473 0.181 1.07 0.971 1.17 0.099 0.047 0.0351 1.1 1.01 1.21 0.12 0.0469 0.0103 1.13 1.03 1.24 ukb-melanoma-gwas-catalog all 480 Pneumonia Respiratory Both 0.999 0.979 1.02 0.905 10456 104475 FALSE 0.0433514207947967 -0.00122 0.0103 -0.0174 0.0291 0.549 0.983 0.928 1.04 -0.00218 0.029 0.94 0.998 0.943 1.06 0.00279 0.0291 0.923 1 0.947 1.06 ukb-melanoma-gwas-catalog all 480.1 Bacterial pneumonia Respiratory Both 0.995 0.97 1.02 0.7 6691 66910 FALSE 0.154901959985743 -0.00495 0.0129 0.0105 0.0362 0.771 1.01 0.941 1.08 -0.0101 0.0364 0.782 0.99 0.922 1.06 0.000841 0.0364 0.982 1 0.932 1.07 ukb-melanoma-gwas-catalog all 480.2 Viral pneumonia Respiratory Both 1.16 0.909 1.48 0.233 73 730 FALSE 0.632644078973981 0.145 0.122 0.105 0.368 0.776 1.11 0.528 2.36 0.249 0.361 0.49 1.28 0.622 2.69 0.572 0.342 0.0946 1.77 0.906 3.59 ukb-melanoma-gwas-catalog all 480.3 Pneumonia due to fungus (mycoses) Respiratory Both 1.32 1.07 1.62 0.00821 101 1010 TRUE 2.08565684288056 0.277 0.105 0.289 0.325 0.374 1.33 0.698 2.59 0.584 0.307 0.0568 1.79 0.984 3.37 0.608 0.307 0.0476 1.84 1.01 3.46 ukb-melanoma-gwas-catalog all 480.5 Bronchopneumonia and lung abscess Respiratory Both 0.944 0.877 1.02 0.123 802 8020 FALSE 0.910094888560602 -0.0575 0.0373 -0.0292 0.103 0.778 0.971 0.792 1.19 -0.0656 0.104 0.53 0.937 0.763 1.15 -0.072 0.105 0.494 0.931 0.757 1.14 ukb-melanoma-gwas-catalog all 480.11 Pneumococcal pneumonia Respiratory Both 0.999 0.973 1.03 0.967 5936 59360 FALSE 0.0145735259169983 -0.00056 0.0137 0.012 0.0385 0.755 1.01 0.939 1.09 -0.00528 0.0387 0.892 0.995 0.922 1.07 0.00831 0.0387 0.83 1.01 0.935 1.09 ukb-melanoma-gwas-catalog all 480.12 Pseudomonal pneumonia Respiratory Both 0.965 0.778 1.2 0.738 93 930 FALSE 0.131943638176958 -0.0361 0.108 0.137 0.304 0.652 1.15 0.626 2.12 0.114 0.307 0.711 1.12 0.606 2.08 0.105 0.311 0.736 1.11 0.597 2.08 ukb-melanoma-gwas-catalog all 481 Influenza Respiratory Both 0.929 0.829 1.04 0.208 331 3310 FALSE 0.681936665037238 -0.0731 0.0581 -0.205 0.162 0.204 0.814 0.591 1.12 -0.00811 0.156 0.959 0.992 0.729 1.35 -0.248 0.165 0.132 0.78 0.563 1.08 ukb-melanoma-gwas-catalog all 483 Acute bronchitis and bronchiolitis Respiratory Both 1.1 0.945 1.27 0.223 194 1940 FALSE 0.651695136951839 0.0913 0.0749 0.39 0.217 0.0716 1.48 0.966 2.28 0.302 0.222 0.175 1.35 0.873 2.11 0.261 0.222 0.239 1.3 0.839 2.02 ukb-melanoma-gwas-catalog all 495 Asthma Respiratory Both 0.993 0.98 1.01 0.272 25799 251156 FALSE 0.565431095965801 -0.00721 0.00656 -0.00365 0.0185 0.844 0.996 0.961 1.03 -0.0229 0.0186 0.218 0.977 0.942 1.01 -0.00197 0.0185 0.916 0.998 0.962 1.03 ukb-melanoma-gwas-catalog all 495.2 Asthma with exacerbation Respiratory Both 0.943 0.828 1.07 0.371 252 2520 FALSE 0.430626090384954 -0.0591 0.066 -0.0385 0.178 0.829 0.962 0.676 1.37 -0.324 0.191 0.0898 0.723 0.494 1.05 -0.124 0.182 0.495 0.883 0.616 1.26 ukb-melanoma-gwas-catalog all 496 Chronic airway obstruction Respiratory Both 1 0.982 1.02 0.829 10487 102024 FALSE 0.0814454694497265 0.00222 0.0103 0.0116 0.0291 0.691 1.01 0.956 1.07 0.00363 0.0292 0.901 1 0.948 1.06 0.018 0.0292 0.538 1.02 0.962 1.08 ukb-melanoma-gwas-catalog all 496.1 Emphysema Respiratory Both 0.952 0.906 1 0.0531 1754 17540 FALSE 1.27490547891853 -0.0487 0.0252 -0.00127 0.0693 0.985 0.999 0.872 1.14 -0.0843 0.071 0.235 0.919 0.8 1.06 -0.119 0.0715 0.0972 0.888 0.772 1.02 ukb-melanoma-gwas-catalog all 496.2 Chronic bronchitis Respiratory Both 0.998 0.961 1.04 0.905 2965 29592 FALSE 0.0433514207947967 -0.0023 0.0193 -0.0126 0.0549 0.818 0.987 0.887 1.1 0.0732 0.054 0.175 1.08 0.968 1.2 -0.0343 0.0554 0.536 0.966 0.867 1.08 ukb-melanoma-gwas-catalog all 496.3 Bronchiectasis Respiratory Both 1.03 0.98 1.08 0.253 1893 18930 FALSE 0.596879478824182 0.0276 0.0242 -0.0241 0.069 0.726 0.976 0.853 1.12 -0.0123 0.0689 0.858 0.988 0.863 1.13 0.0897 0.0676 0.184 1.09 0.958 1.25 ukb-melanoma-gwas-catalog all 496.21 Obstructive chronic bronchitis Respiratory Both 1 0.963 1.04 0.922 2722 27164 FALSE 0.0352690789463706 0.00199 0.0202 -0.000443 0.0574 0.994 1 0.893 1.12 0.102 0.0563 0.0707 1.11 0.991 1.24 -0.0332 0.0581 0.568 0.967 0.863 1.08 ukb-melanoma-gwas-catalog all 497 Bronchitis Respiratory Both 1.02 0.938 1.11 0.665 634 6332 FALSE 0.177178354696895 0.0181 0.0417 -0.119 0.117 0.307 0.888 0.705 1.12 -0.202 0.119 0.0899 0.817 0.645 1.03 0.00366 0.114 0.974 1 0.802 1.26 ukb-melanoma-gwas-catalog all 500 Lung disease due to external agents Respiratory Both 1.12 1.01 1.24 0.0241 413 4113 TRUE 1.61798295742513 0.116 0.0514 0.236 0.148 0.111 1.27 0.947 1.7 0.129 0.152 0.394 1.14 0.845 1.54 0.237 0.148 0.11 1.27 0.947 1.7 ukb-melanoma-gwas-catalog all 500.1 Extrinsic allergic alveolitis Respiratory Both 1.07 0.848 1.35 0.564 79 790 FALSE 0.248720896016658 0.0671 0.116 0.437 0.327 0.182 1.55 0.813 3.01 -0.145 0.356 0.684 0.865 0.419 1.77 0.177 0.332 0.594 1.19 0.616 2.34 ukb-melanoma-gwas-catalog all 500.2 Pneumoconiosis Respiratory Both 1.17 1.02 1.33 0.0205 244 2423 TRUE 1.68824613894425 0.154 0.0666 0.25 0.197 0.203 1.28 0.872 1.9 0.329 0.194 0.0902 1.39 0.95 2.05 0.26 0.197 0.188 1.3 0.88 1.92 ukb-melanoma-gwas-catalog all 501 Pneumonitis due to inhalation of food or vomitus Respiratory Both 1.04 0.958 1.13 0.356 657 6570 FALSE 0.448550002027125 0.0379 0.0411 0.209 0.117 0.0758 1.23 0.979 1.55 0.18 0.118 0.128 1.2 0.949 1.51 0.152 0.12 0.205 1.16 0.92 1.47 ukb-melanoma-gwas-catalog all 502 Postinflammatory pulmonary fibrosis Respiratory Both 0.986 0.922 1.06 0.693 924 9240 FALSE 0.159266765388193 -0.0136 0.0346 -0.0139 0.0967 0.885 0.986 0.816 1.19 -0.0947 0.0984 0.336 0.91 0.75 1.1 0.00493 0.0969 0.959 1 0.831 1.22 ukb-melanoma-gwas-catalog all 503 Pulmonary congestion and hypostasis Respiratory Both 0.994 0.908 1.09 0.902 515 5150 FALSE 0.0447934624580583 -0.00572 0.0463 0.211 0.129 0.102 1.23 0.959 1.59 0.0946 0.132 0.475 1.1 0.847 1.43 0.0155 0.135 0.909 1.02 0.778 1.33 ukb-melanoma-gwas-catalog all 504 Other alveolar and parietoalveolar pneumonopathy Respiratory Both 0.96 0.856 1.08 0.481 330 3300 FALSE 0.317854923626168 -0.0408 0.0579 -0.184 0.164 0.26 0.832 0.601 1.15 -0.14 0.161 0.386 0.87 0.633 1.19 -0.0268 0.158 0.866 0.974 0.712 1.33 ukb-melanoma-gwas-catalog all 505 Other pulmonary inflamation or edema Respiratory Both 0.853 0.657 1.11 0.224 61 610 FALSE 0.649751981665837 -0.159 0.131 0.0228 0.348 0.948 1.02 0.511 2.06 -0.089 0.357 0.803 0.915 0.446 1.87 -0.548 0.405 0.176 0.578 0.245 1.29 ukb-melanoma-gwas-catalog all 506 Empyema and pneumothorax Respiratory Both 0.993 0.935 1.05 0.816 1181 11803 FALSE 0.0883098412461389 -0.00715 0.0307 -0.135 0.0874 0.124 0.874 0.736 1.04 -0.0133 0.0851 0.876 0.987 0.835 1.17 -0.0354 0.0859 0.68 0.965 0.815 1.14 ukb-melanoma-gwas-catalog all 507 Pleurisy; pleural effusion Respiratory Both 0.992 0.967 1.02 0.553 6440 64382 FALSE 0.257274868695302 -0.00778 0.0131 0.0158 0.0369 0.667 1.02 0.945 1.09 0.00271 0.037 0.942 1 0.933 1.08 -0.0208 0.0373 0.577 0.979 0.91 1.05 ukb-melanoma-gwas-catalog all 508 Pulmonary collapse; interstitial and compensatory emphysema Respiratory Both 0.979 0.935 1.02 0.361 2002 20020 FALSE 0.442492798094342 -0.0215 0.0235 -0.0973 0.0659 0.14 0.907 0.797 1.03 -0.0683 0.0655 0.297 0.934 0.821 1.06 -0.0903 0.0661 0.171 0.914 0.802 1.04 ukb-melanoma-gwas-catalog all 509 Respiratory failure, insufficiency, arrest Respiratory Both 1.01 0.971 1.05 0.613 2648 26474 FALSE 0.212539525481585 0.0103 0.0205 -0.0515 0.0579 0.373 0.95 0.848 1.06 -0.0391 0.0578 0.499 0.962 0.859 1.08 0.0124 0.0573 0.829 1.01 0.905 1.13 ukb-melanoma-gwas-catalog all 509.1 Respiratory failure Respiratory Both 1.01 0.966 1.06 0.631 2079 20784 FALSE 0.199970640755866 0.0111 0.0231 -0.107 0.0659 0.105 0.899 0.79 1.02 -0.0332 0.0649 0.608 0.967 0.852 1.1 0.0306 0.0642 0.634 1.03 0.909 1.17 ukb-melanoma-gwas-catalog all 509.2 Respiratory insufficiency Respiratory Both 1 0.957 1.05 0.863 1819 18184 FALSE 0.0639892042847904 0.00426 0.0247 -0.13 0.0702 0.064 0.878 0.765 1.01 -0.0796 0.0695 0.252 0.923 0.806 1.06 0.0184 0.0682 0.787 1.02 0.891 1.16 ukb-melanoma-gwas-catalog all 509.5 Respiratory arrest Respiratory Both 1.01 0.853 1.2 0.881 144 1440 FALSE 0.0550240915879521 0.013 0.0866 0.231 0.251 0.358 1.26 0.768 2.08 0.288 0.248 0.245 1.33 0.818 2.2 0.1 0.258 0.697 1.11 0.662 1.85 ukb-melanoma-gwas-catalog all 509.8 Dependence on respirator [Ventilator] or supplemental oxygen Respiratory Both 1.04 0.94 1.16 0.42 389 3890 FALSE 0.3767507096021 0.0429 0.0531 0.0308 0.148 0.835 1.03 0.77 1.38 -0.0783 0.152 0.606 0.925 0.685 1.25 -0.0242 0.15 0.871 0.976 0.727 1.31 ukb-melanoma-gwas-catalog all 510 Other diseases of lung Respiratory Both 1.05 0.975 1.13 0.191 757 7570 FALSE 0.718966632752272 0.0499 0.0382 0.21 0.11 0.056 1.23 0.995 1.53 0.238 0.109 0.0296 1.27 1.02 1.57 0.127 0.113 0.259 1.14 0.91 1.42 ukb-melanoma-gwas-catalog all 512 Other symptoms of respiratory system Respiratory Both 1.02 0.999 1.04 0.057 9079 90783 FALSE 1.24412514432751 0.021 0.011 -0.0144 0.0314 0.648 0.986 0.927 1.05 0.0233 0.0312 0.456 1.02 0.963 1.09 0.0359 0.0312 0.25 1.04 0.975 1.1 ukb-melanoma-gwas-catalog all 512.1 Wheezing Respiratory Both 1.06 0.926 1.22 0.375 220 2200 FALSE 0.425968732272281 0.0624 0.0704 0.00876 0.207 0.966 1.01 0.67 1.52 0.114 0.2 0.569 1.12 0.755 1.67 0.191 0.197 0.333 1.21 0.821 1.79 ukb-melanoma-gwas-catalog all 512.2 Painful respiration Respiratory Both 0.967 0.838 1.12 0.644 208 2080 FALSE 0.191114132640188 -0.0335 0.0726 -0.0316 0.203 0.876 0.969 0.647 1.45 0.0614 0.2 0.759 1.06 0.716 1.58 -0.102 0.207 0.622 0.903 0.598 1.36 ukb-melanoma-gwas-catalog all 512.7 Shortness of breath Respiratory Both 1.02 0.991 1.05 0.195 5855 58547 FALSE 0.709965388637482 0.0178 0.0138 -0.0249 0.039 0.524 0.975 0.904 1.05 -0.00649 0.0389 0.867 0.994 0.921 1.07 0.0299 0.0387 0.44 1.03 0.955 1.11 ukb-melanoma-gwas-catalog all 512.8 Cough Respiratory Both 1.03 0.991 1.07 0.129 2864 28636 FALSE 0.889410289700751 0.0298 0.0196 0.0395 0.0564 0.484 1.04 0.931 1.16 0.111 0.0556 0.045 1.12 1 1.25 0.0722 0.0562 0.199 1.07 0.963 1.2 ukb-melanoma-gwas-catalog all 512.9 Other dyspnea Respiratory Both 1.03 0.965 1.11 0.347 907 9070 FALSE 0.459670525209126 0.0327 0.0349 0.0306 0.0995 0.759 1.03 0.848 1.25 0.0383 0.0995 0.7 1.04 0.855 1.26 0.0762 0.0988 0.441 1.08 0.889 1.31 ukb-melanoma-gwas-catalog all 513 Respiratory abnormalities Respiratory Both 1.11 1.02 1.2 0.0177 614 6136 TRUE 1.75202673363819 0.1 0.0423 -0.0601 0.124 0.627 0.942 0.738 1.2 0.00699 0.122 0.954 1.01 0.792 1.28 0.217 0.117 0.0638 1.24 0.988 1.56 ukb-melanoma-gwas-catalog all 513.3 Hypoventilation Respiratory Both 1.15 0.917 1.45 0.219 83 830 FALSE 0.659555885159882 0.142 0.116 -0.0589 0.333 0.86 0.943 0.481 1.84 -0.0873 0.337 0.795 0.916 0.464 1.8 0.427 0.311 0.169 1.53 0.832 2.88 ukb-melanoma-gwas-catalog all 513.4 Hyperventilation Respiratory Both 1.05 0.926 1.19 0.453 278 2780 FALSE 0.343901797987168 0.047 0.0627 0.0967 0.179 0.59 1.1 0.773 1.57 0.0497 0.181 0.784 1.05 0.735 1.5 0.144 0.177 0.419 1.15 0.814 1.64 ukb-melanoma-gwas-catalog all 513.8 Disorders of diaphragm Respiratory Both 1.02 0.861 1.2 0.845 154 1540 FALSE 0.0731432910503077 0.0165 0.0841 -0.115 0.236 0.626 0.892 0.557 1.42 -0.0993 0.236 0.674 0.905 0.566 1.44 -0.0665 0.232 0.774 0.936 0.59 1.48 ukb-melanoma-gwas-catalog all 514 Abnormal findings examination of lungs Respiratory Both 0.999 0.958 1.04 0.953 2473 24719 FALSE 0.0209070993616736 -0.00125 0.0212 -0.058 0.0601 0.335 0.944 0.839 1.06 0.0309 0.059 0.6 1.03 0.919 1.16 -0.0351 0.0601 0.559 0.965 0.858 1.09 ukb-melanoma-gwas-catalog all 516 Abnormal sputum Respiratory Both 1 0.96 1.05 0.891 2172 21713 FALSE 0.0501222959631252 0.0031 0.0226 -0.0205 0.0638 0.748 0.98 0.864 1.11 0.0309 0.0631 0.624 1.03 0.911 1.17 -0.0553 0.0645 0.391 0.946 0.834 1.07 ukb-melanoma-gwas-catalog all 516.1 Hemoptysis Respiratory Both 1 0.96 1.05 0.858 2079 20781 FALSE 0.0665127121512946 0.00412 0.0231 0.000259 0.0652 0.997 1 0.88 1.14 0.0522 0.0646 0.419 1.05 0.928 1.2 -0.0471 0.0662 0.477 0.954 0.838 1.09 ukb-melanoma-gwas-catalog all 519 Other diseases of respiratory system, not elsewhere classified Respiratory Both 1.01 0.99 1.03 0.301 9497 94944 FALSE 0.521433504406157 0.0112 0.0108 0.0489 0.0305 0.109 1.05 0.989 1.11 0.0158 0.0308 0.608 1.02 0.956 1.08 0.0414 0.0307 0.177 1.04 0.981 1.11 ukb-melanoma-gwas-catalog all 519.2 Respiratory complications Respiratory Both 0.974 0.869 1.09 0.645 328 3280 FALSE 0.190440285364732 -0.0267 0.0579 -0.0379 0.161 0.814 0.963 0.7 1.32 -0.0552 0.162 0.733 0.946 0.687 1.3 -0.0606 0.163 0.711 0.941 0.681 1.3 ukb-melanoma-gwas-catalog all 519.8 Other diseases of respiratory system, NEC Respiratory Both 1.01 0.987 1.03 0.413 8881 88784 FALSE 0.384049948343599 0.00914 0.0112 0.0502 0.0315 0.111 1.05 0.988 1.12 0.0174 0.0318 0.584 1.02 0.956 1.08 0.0358 0.0318 0.26 1.04 0.974 1.1 ukb-melanoma-gwas-catalog all 519.9 Symptoms involving respiratory system and other chest symptoms Respiratory Both 1.07 0.953 1.21 0.242 305 3050 FALSE 0.616184634019569 0.0701 0.0599 0.083 0.17 0.625 1.09 0.778 1.52 -0.0485 0.175 0.781 0.953 0.675 1.34 0.209 0.168 0.212 1.23 0.887 1.72 ukb-melanoma-gwas-catalog all 520 Disorders of tooth development Digestive Both 0.985 0.945 1.03 0.484 2446 24460 FALSE 0.315154638355588 -0.0149 0.0213 -0.0649 0.0602 0.281 0.937 0.833 1.05 -0.0286 0.0597 0.632 0.972 0.864 1.09 -0.0307 0.0598 0.608 0.97 0.862 1.09 ukb-melanoma-gwas-catalog all 520.1 Hereditary disturbances in tooth structure Digestive Both 1.03 0.778 1.37 0.816 53 530 FALSE 0.0883098412461389 0.033 0.142 0.0819 0.4 0.838 1.09 0.484 2.46 0.194 0.396 0.624 1.21 0.547 2.74 -0.0369 0.411 0.928 0.964 0.418 2.22 ukb-melanoma-gwas-catalog all 520.2 Disturbances in tooth eruption Digestive Both 0.987 0.946 1.03 0.553 2361 23610 FALSE 0.257274868695302 -0.0129 0.0217 -0.0809 0.0613 0.187 0.922 0.818 1.04 -0.0372 0.0607 0.54 0.963 0.855 1.09 -0.0279 0.0607 0.646 0.972 0.863 1.1 ukb-melanoma-gwas-catalog all 521 Diseases of hard tissues of teeth Digestive Both 1.01 0.969 1.04 0.776 3087 30870 FALSE 0.110138278741812 0.00538 0.0189 0.00141 0.0535 0.979 1 0.902 1.11 -0.00859 0.0537 0.873 0.991 0.892 1.1 0.0214 0.0535 0.689 1.02 0.92 1.13 ukb-melanoma-gwas-catalog all 521.1 Dental caries Digestive Both 1 0.967 1.04 0.831 3047 30470 FALSE 0.080398976215889 0.00406 0.0191 -0.00506 0.0538 0.925 0.995 0.895 1.11 -0.0193 0.0541 0.721 0.981 0.882 1.09 0.0186 0.0537 0.729 1.02 0.917 1.13 ukb-melanoma-gwas-catalog all 522 Diseases of pulp and periapical tissues Digestive Both 0.99 0.943 1.04 0.693 1792 17917 FALSE 0.159266765388193 -0.00982 0.0249 -0.113 0.0707 0.11 0.893 0.777 1.03 -0.00949 0.0691 0.891 0.991 0.865 1.13 -0.038 0.0696 0.585 0.963 0.84 1.1 ukb-melanoma-gwas-catalog all 522.5 Periapical abscess Digestive Both 0.968 0.911 1.03 0.287 1175 11750 FALSE 0.542118103266008 -0.0327 0.0307 -0.109 0.0866 0.209 0.897 0.756 1.06 0.00841 0.0844 0.921 1.01 0.854 1.19 -0.122 0.0869 0.161 0.885 0.746 1.05 ukb-melanoma-gwas-catalog all 523 Gingival and periodontal diseases Digestive Both 0.968 0.922 1.02 0.203 1741 17410 FALSE 0.692503962086787 -0.0321 0.0252 -0.0772 0.0702 0.272 0.926 0.806 1.06 -0.128 0.0712 0.071 0.879 0.765 1.01 -0.0691 0.0703 0.326 0.933 0.813 1.07 ukb-melanoma-gwas-catalog all 523.1 Gingivitis Digestive Both 0.991 0.817 1.2 0.929 114 1140 FALSE 0.0319842860063582 -0.00873 0.0975 -0.359 0.282 0.203 0.698 0.394 1.22 -0.227 0.276 0.411 0.797 0.457 1.38 0.0271 0.257 0.916 1.03 0.617 1.71 ukb-melanoma-gwas-catalog all 523.3 Periodontitis (acute or chronic) Digestive Both 0.961 0.906 1.02 0.185 1222 12220 FALSE 0.732828271596986 -0.0399 0.0301 -0.0476 0.0839 0.57 0.954 0.809 1.12 -0.0826 0.0845 0.328 0.921 0.78 1.09 -0.073 0.0846 0.388 0.93 0.787 1.1 ukb-melanoma-gwas-catalog all 523.31 Acute periodontitis Digestive Both 1.02 0.94 1.1 0.657 668 6680 FALSE 0.182434630440219 0.018 0.0406 0.0682 0.116 0.557 1.07 0.852 1.35 0.0559 0.116 0.631 1.06 0.841 1.33 0.127 0.115 0.268 1.14 0.906 1.42 ukb-melanoma-gwas-catalog all 523.32 Chronic periodontitis Digestive Both 0.894 0.819 0.976 0.0123 561 5610 TRUE 1.9100948885606 -0.112 0.0445 -0.15 0.121 0.216 0.861 0.677 1.09 -0.162 0.122 0.183 0.85 0.669 1.08 -0.273 0.126 0.0298 0.761 0.593 0.974 ukb-melanoma-gwas-catalog all 524 Dentofacial anomalies, including malocclusion Digestive Both 1.1 0.984 1.23 0.0922 345 3450 FALSE 1.03526907894637 0.0951 0.0564 0.00545 0.167 0.974 1.01 0.723 1.4 0.0775 0.165 0.64 1.08 0.78 1.5 0.354 0.157 0.0238 1.43 1.05 1.95 ukb-melanoma-gwas-catalog all 524.3 Anomalies of tooth position/malocclusion Digestive Both 1.1 0.974 1.23 0.128 305 3050 FALSE 0.892790030352132 0.0913 0.06 -0.0244 0.177 0.89 0.976 0.688 1.38 0.0537 0.174 0.758 1.06 0.748 1.49 0.306 0.166 0.0657 1.36 0.98 1.89 ukb-melanoma-gwas-catalog all 525 Other diseases of the teeth and supporting structures Digestive Both 0.979 0.941 1.02 0.302 2685 26850 FALSE 0.519993057042849 -0.021 0.0203 -0.0884 0.0569 0.12 0.915 0.819 1.02 -0.0732 0.0568 0.197 0.929 0.831 1.04 -0.0923 0.0572 0.106 0.912 0.815 1.02 ukb-melanoma-gwas-catalog all 525.2 Atrophy of edentulous alveolar ridge Digestive Both 0.889 0.697 1.13 0.334 72 720 FALSE 0.476253533188435 -0.118 0.122 -0.0812 0.324 0.802 0.922 0.48 1.76 -0.329 0.34 0.334 0.72 0.359 1.41 -0.343 0.337 0.309 0.71 0.357 1.38 ukb-melanoma-gwas-catalog all 526 Diseases of the jaws Digestive Both 0.985 0.921 1.05 0.65 959 9590 FALSE 0.187086643357144 -0.0154 0.034 -0.104 0.0959 0.278 0.901 0.746 1.09 -0.135 0.0967 0.162 0.873 0.722 1.06 0.031 0.0935 0.74 1.03 0.859 1.24 ukb-melanoma-gwas-catalog all 526.1 Cysts of the jaws Digestive Both 0.969 0.865 1.09 0.592 329 3290 FALSE 0.22767829327708 -0.031 0.0579 -0.127 0.163 0.435 0.88 0.638 1.21 -0.123 0.163 0.451 0.884 0.64 1.22 -0.00494 0.159 0.975 0.995 0.727 1.36 ukb-melanoma-gwas-catalog all 526.3 Anomalies of jaw size/symmetry Digestive Both 0.945 0.726 1.23 0.67 61 610 FALSE 0.173925197299174 -0.0565 0.133 -0.262 0.372 0.481 0.769 0.361 1.61 0.0712 0.346 0.837 1.07 0.538 2.15 -0.364 0.385 0.345 0.695 0.315 1.49 ukb-melanoma-gwas-catalog all 526.4 Temporomandibular joint disorders Digestive Both 0.997 0.872 1.14 0.966 240 2400 FALSE 0.0150228735845067 -0.00285 0.0676 -0.17 0.19 0.37 0.843 0.578 1.23 -0.206 0.191 0.282 0.814 0.556 1.19 0.009 0.183 0.961 1.01 0.703 1.45 ukb-melanoma-gwas-catalog all 526.5 Inflammatory conditions of jaw Digestive Both 0.98 0.805 1.19 0.839 110 1100 FALSE 0.0762380391712997 -0.0201 0.0991 -0.166 0.282 0.555 0.847 0.48 1.48 -0.268 0.284 0.346 0.765 0.431 1.34 0.0925 0.266 0.728 1.1 0.647 1.86 ukb-melanoma-gwas-catalog all 526.9 Jaw disease NOS Digestive Both 1 0.875 1.15 0.974 234 2340 FALSE 0.0114410431213845 0.00226 0.0688 0.0169 0.195 0.931 1.02 0.691 1.5 0.00959 0.196 0.961 1.01 0.685 1.49 0.106 0.193 0.584 1.11 0.76 1.63 ukb-melanoma-gwas-catalog all 526.41 Temporomandibular joint disorder, unspecified Digestive Both 0.996 0.869 1.14 0.95 233 2330 FALSE 0.0222763947111523 -0.00434 0.0686 -0.174 0.193 0.367 0.84 0.572 1.23 -0.194 0.194 0.316 0.823 0.56 1.21 0.0115 0.186 0.951 1.01 0.701 1.46 ukb-melanoma-gwas-catalog all 527 Diseases of the salivary glands Digestive Both 0.982 0.908 1.06 0.637 710 7100 FALSE 0.19586056766465 -0.0186 0.0395 -0.0264 0.113 0.815 0.974 0.78 1.22 0.137 0.109 0.209 1.15 0.926 1.42 -0.0436 0.114 0.701 0.957 0.766 1.2 ukb-melanoma-gwas-catalog all 527.1 Hypertrophy of salivary gland Digestive Both 0.938 0.748 1.17 0.571 84 840 FALSE 0.243363891754152 -0.0642 0.113 0.0213 0.325 0.948 1.02 0.532 1.97 0.206 0.312 0.51 1.23 0.661 2.31 0.0357 0.326 0.913 1.04 0.538 2 ukb-melanoma-gwas-catalog all 527.2 Sialoadenitis Digestive Both 0.975 0.875 1.09 0.643 366 3660 FALSE 0.191789027075778 -0.0255 0.0549 -0.156 0.156 0.316 0.855 0.628 1.16 -0.03 0.153 0.844 0.97 0.718 1.31 -0.0319 0.152 0.834 0.969 0.718 1.31 ukb-melanoma-gwas-catalog all 527.7 Disturbance of salivary secretion Digestive Both 0.94 0.723 1.22 0.633 63 630 FALSE 0.198596289982645 -0.0623 0.131 0.123 0.363 0.735 1.13 0.545 2.36 0.354 0.351 0.314 1.42 0.712 2.91 -0.37 0.402 0.358 0.691 0.298 1.55 ukb-melanoma-gwas-catalog all 527.8 Other specified diseases of the salivary glands Digestive Both 1.09 0.903 1.32 0.366 120 1200 FALSE 0.436518914605589 0.0862 0.0953 0.23 0.28 0.413 1.26 0.722 2.21 0.325 0.275 0.237 1.38 0.804 2.41 0.271 0.278 0.329 1.31 0.758 2.3 ukb-melanoma-gwas-catalog all 528 Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue Digestive Both 1.02 0.983 1.05 0.36 3927 39270 FALSE 0.443697499232713 0.0154 0.0168 -0.0882 0.048 0.0662 0.916 0.833 1.01 0.0404 0.0467 0.387 1.04 0.95 1.14 -0.0157 0.0474 0.74 0.984 0.897 1.08 ukb-melanoma-gwas-catalog all 528.1 Stomatitis and mucositis Digestive Both 1.05 0.953 1.15 0.334 469 4690 FALSE 0.476253533188435 0.0468 0.0484 -0.0385 0.138 0.78 0.962 0.733 1.26 0.0552 0.136 0.684 1.06 0.81 1.38 0.0182 0.137 0.894 1.02 0.778 1.33 ukb-melanoma-gwas-catalog all 528.3 Cellulitis and abscess of oral soft tissues Digestive Both 0.978 0.838 1.14 0.777 181 1810 FALSE 0.109578981199086 -0.0221 0.0782 -0.305 0.232 0.189 0.737 0.462 1.16 0.0476 0.215 0.825 1.05 0.686 1.61 0.0226 0.215 0.916 1.02 0.668 1.57 ukb-melanoma-gwas-catalog all 528.4 Cysts of oral soft tissues Digestive Both 0.933 0.775 1.12 0.455 125 1250 FALSE 0.341988603342888 -0.0698 0.0934 0.0111 0.265 0.966 1.01 0.597 1.71 0.145 0.258 0.575 1.16 0.693 1.94 0.0205 0.264 0.938 1.02 0.603 1.73 ukb-melanoma-gwas-catalog all 528.5 Diseases of lips Digestive Both 1.06 0.98 1.15 0.147 682 6820 FALSE 0.832682665251824 0.0581 0.0401 -0.0269 0.117 0.817 0.973 0.774 1.22 0.122 0.113 0.283 1.13 0.904 1.41 0.114 0.114 0.316 1.12 0.897 1.4 ukb-melanoma-gwas-catalog all 528.6 Leukoplakia of oral mucosa Digestive Both 1.03 0.918 1.16 0.589 308 3080 FALSE 0.229884705212898 0.0322 0.0597 -0.0287 0.169 0.865 0.972 0.696 1.36 0.0201 0.167 0.904 1.02 0.734 1.42 -0.0116 0.169 0.945 0.988 0.708 1.38 ukb-melanoma-gwas-catalog all 528.7 Sialolithiasis Digestive Both 0.994 0.885 1.12 0.92 314 3140 FALSE 0.0362121726544447 -0.00592 0.0592 -0.372 0.175 0.0332 0.689 0.487 0.97 -0.077 0.163 0.636 0.926 0.672 1.28 0.016 0.16 0.92 1.02 0.742 1.39 ukb-melanoma-gwas-catalog all 528.11 Stomatitis and mucositis (ulcerative) Digestive Both 1.05 0.948 1.17 0.338 390 3900 FALSE 0.471083299722345 0.0508 0.0531 -0.009 0.154 0.953 0.991 0.732 1.34 0.165 0.148 0.266 1.18 0.882 1.58 0.0756 0.152 0.619 1.08 0.8 1.46 ukb-melanoma-gwas-catalog all 528.12 Oral aphthae Digestive Both 1.01 0.807 1.27 0.907 84 840 FALSE 0.0423927129399047 0.0132 0.113 -0.263 0.316 0.405 0.769 0.405 1.44 -0.28 0.313 0.371 0.756 0.401 1.4 -0.226 0.307 0.462 0.798 0.43 1.47 ukb-melanoma-gwas-catalog all 528.41 Cyst of the salivary gland Digestive Both 0.956 0.773 1.18 0.673 94 940 FALSE 0.171984935776023 -0.0451 0.107 -0.0736 0.312 0.813 0.929 0.495 1.73 0.359 0.287 0.211 1.43 0.814 2.56 -0.0752 0.311 0.809 0.928 0.496 1.73 ukb-melanoma-gwas-catalog all 529 Diseases and other conditions of the tongue Digestive Both 1.05 0.99 1.11 0.101 1235 12344 FALSE 0.995678626217357 0.0489 0.0299 -0.0204 0.0856 0.811 0.98 0.828 1.16 -0.0201 0.0856 0.815 0.98 0.828 1.16 0.121 0.0833 0.147 1.13 0.958 1.33 ukb-melanoma-gwas-catalog all 529.1 Glossitis Digestive Both 1.12 0.994 1.26 0.0612 299 2990 FALSE 1.21324857785444 0.113 0.0605 0.0422 0.173 0.807 1.04 0.742 1.47 -0.0516 0.176 0.77 0.95 0.67 1.34 0.195 0.168 0.247 1.21 0.873 1.7 ukb-melanoma-gwas-catalog all 530 Diseases of esophagus Digestive Both 1.02 1.01 1.03 0.000215 33704 280049 TRUE 3.66756154008439 0.0214 0.00579 0.0193 0.0165 0.242 1.02 0.987 1.05 0.0257 0.0165 0.119 1.03 0.993 1.06 0.0528 0.0164 0.0013 1.05 1.02 1.09 ukb-melanoma-gwas-catalog all 530.1 Esophagitis, GERD and related diseases Digestive Both 1.02 1.01 1.03 0.000893 31312 260239 TRUE 3.04914854111145 0.02 0.00601 0.0287 0.0171 0.0932 1.03 0.995 1.06 0.0353 0.0171 0.0389 1.04 1 1.07 0.051 0.0171 0.00278 1.05 1.02 1.09 ukb-melanoma-gwas-catalog all 530.2 Esophageal bleeding (varices/hemorrhage) Digestive Both 1.06 1.01 1.12 0.0151 1683 16830 TRUE 1.82102305270683 0.0622 0.0256 -0.0778 0.0737 0.291 0.925 0.8 1.07 -0.0703 0.0736 0.339 0.932 0.807 1.08 0.139 0.0705 0.049 1.15 1 1.32 ukb-melanoma-gwas-catalog all 530.3 Stricture and stenosis of esophagus Digestive Both 1.03 0.98 1.08 0.255 1873 18730 FALSE 0.593459819566045 0.0276 0.0243 -0.0231 0.0689 0.737 0.977 0.854 1.12 0.000855 0.0685 0.99 1 0.875 1.14 0.0039 0.0686 0.955 1 0.877 1.15 ukb-melanoma-gwas-catalog all 530.5 Disorders of esophageal motility Digestive Both 1.03 0.951 1.12 0.453 638 6380 FALSE 0.343901797987168 0.0311 0.0415 -0.0707 0.119 0.553 0.932 0.737 1.18 -0.027 0.118 0.819 0.973 0.772 1.23 0.0898 0.115 0.435 1.09 0.873 1.37 ukb-melanoma-gwas-catalog all 530.6 Diverticulum of esophagus, acquired Digestive Both 0.913 0.772 1.08 0.28 153 1529 FALSE 0.552841968657781 -0.0914 0.0846 0.0789 0.233 0.735 1.08 0.681 1.72 0.0766 0.235 0.744 1.08 0.677 1.72 -0.135 0.244 0.579 0.873 0.537 1.42 ukb-melanoma-gwas-catalog all 530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive Both 1.02 0.912 1.14 0.729 344 3440 FALSE 0.137272471682025 0.0196 0.0565 -0.218 0.165 0.188 0.804 0.579 1.11 0.106 0.154 0.491 1.11 0.822 1.51 -0.0477 0.159 0.765 0.953 0.696 1.31 ukb-melanoma-gwas-catalog all 530.9 Heartburn Digestive Both 1.02 0.973 1.07 0.431 2096 20960 FALSE 0.365522729839268 0.0181 0.023 -0.0271 0.0642 0.673 0.973 0.858 1.1 -0.114 0.0656 0.0822 0.892 0.784 1.01 0.0148 0.0639 0.817 1.01 0.895 1.15 ukb-melanoma-gwas-catalog all 530.11 GERD Digestive Both 1.02 0.998 1.03 0.0839 14058 140580 FALSE 1.0762380391713 0.0153 0.00887 0.00791 0.0252 0.754 1.01 0.959 1.06 0.0409 0.0251 0.103 1.04 0.992 1.09 0.0386 0.0252 0.125 1.04 0.989 1.09 ukb-melanoma-gwas-catalog all 530.12 Ulcer of esophagus Digestive Both 1.02 0.99 1.05 0.2 5219 52184 FALSE 0.698970004336019 0.0187 0.0146 -0.00808 0.0415 0.846 0.992 0.914 1.08 0.0543 0.041 0.185 1.06 0.974 1.14 0.0255 0.0414 0.537 1.03 0.946 1.11 ukb-melanoma-gwas-catalog all 530.14 Reflux esophagitis Digestive Both 1.01 0.987 1.03 0.496 10473 104727 FALSE 0.304518323509803 0.00699 0.0103 0.0261 0.0291 0.368 1.03 0.97 1.09 0.00314 0.0292 0.914 1 0.947 1.06 0.0292 0.0291 0.316 1.03 0.973 1.09 ukb-melanoma-gwas-catalog all 531 Peptic ulcer (excl. esophageal) Digestive Both 1.02 0.998 1.05 0.0753 7421 74192 FALSE 1.1232050237993 0.0217 0.0122 0.0245 0.0349 0.483 1.02 0.957 1.1 0.0898 0.0345 0.00921 1.09 1.02 1.17 0.0479 0.0349 0.17 1.05 0.98 1.12 ukb-melanoma-gwas-catalog all 531.1 Hemorrhage from gastrointestinal ulcer Digestive Both 1.01 0.933 1.1 0.768 634 6340 FALSE 0.114638779968488 0.0123 0.0417 0.065 0.117 0.578 1.07 0.848 1.34 0.0191 0.118 0.871 1.02 0.808 1.29 -0.00629 0.119 0.958 0.994 0.787 1.26 ukb-melanoma-gwas-catalog all 531.2 Gastric ulcer Digestive Both 1.02 0.988 1.05 0.223 4099 40979 FALSE 0.651695136951839 0.02 0.0164 -0.0273 0.0471 0.562 0.973 0.887 1.07 0.0585 0.0462 0.205 1.06 0.968 1.16 0.0409 0.0466 0.38 1.04 0.951 1.14 ukb-melanoma-gwas-catalog all 531.3 Duodenal ulcer Digestive Both 1.01 0.972 1.05 0.644 2994 29933 FALSE 0.191114132640188 0.00887 0.0192 0.0342 0.0548 0.533 1.03 0.929 1.15 0.0822 0.0544 0.131 1.09 0.976 1.21 0.0454 0.0549 0.409 1.05 0.94 1.17 ukb-melanoma-gwas-catalog all 531.4 Peptic ulcer, site unspecified Digestive Both 1.1 0.996 1.22 0.0581 424 4240 FALSE 1.23582386760967 0.0967 0.051 0.157 0.146 0.283 1.17 0.878 1.56 0.185 0.147 0.21 1.2 0.901 1.61 0.144 0.148 0.331 1.15 0.864 1.55 ukb-melanoma-gwas-catalog all 532 Dysphagia Digestive Both 1.03 1 1.05 0.0408 6447 64466 TRUE 1.38933983691012 0.0268 0.0131 0.0387 0.0373 0.299 1.04 0.966 1.12 0.0343 0.0374 0.359 1.03 0.962 1.11 0.0772 0.0371 0.0376 1.08 1 1.16 ukb-melanoma-gwas-catalog all 535 Gastritis and duodenitis Digestive Both 1.01 1 1.03 0.0375 28309 262547 TRUE 1.42596873227228 0.0131 0.00628 0.031 0.0178 0.0821 1.03 0.996 1.07 0.0235 0.0179 0.188 1.02 0.989 1.06 0.04 0.0178 0.0248 1.04 1.01 1.08 ukb-melanoma-gwas-catalog all 535.1 Acute gastritis Digestive Both 1.03 0.966 1.09 0.414 1185 11850 FALSE 0.382999658879101 0.0249 0.0305 0.0347 0.0871 0.691 1.04 0.873 1.23 0.03 0.0873 0.731 1.03 0.868 1.22 0.103 0.086 0.232 1.11 0.936 1.31 ukb-melanoma-gwas-catalog all 535.2 Atrophic gastritis Digestive Both 0.989 0.888 1.1 0.836 370 3690 FALSE 0.0777937225609836 -0.0112 0.0545 -0.0107 0.154 0.945 0.989 0.731 1.34 0.059 0.152 0.698 1.06 0.787 1.43 -0.0332 0.155 0.831 0.967 0.712 1.31 ukb-melanoma-gwas-catalog all 535.6 Duodenitis Digestive Both 1.01 0.985 1.03 0.491 7605 76045 FALSE 0.308918507877032 0.00832 0.0121 0.063 0.034 0.0637 1.07 0.996 1.14 0.0188 0.0344 0.584 1.02 0.953 1.09 0.022 0.0344 0.522 1.02 0.956 1.09 ukb-melanoma-gwas-catalog all 535.8 Other specified gastritis Digestive Both 0.996 0.973 1.02 0.705 8094 80940 FALSE 0.151810883008601 -0.00443 0.0117 0.0153 0.0331 0.643 1.02 0.952 1.08 0.0393 0.0329 0.233 1.04 0.975 1.11 -0.00924 0.0334 0.782 0.991 0.928 1.06 ukb-melanoma-gwas-catalog all 535.9 Gastritis and duodenitis, NOS Digestive Both 0.937 0.776 1.13 0.494 120 1192 FALSE 0.306273051076353 -0.0651 0.0952 -0.256 0.268 0.339 0.774 0.451 1.31 0.0819 0.25 0.743 1.09 0.662 1.78 -0.349 0.274 0.202 0.705 0.405 1.21 ukb-melanoma-gwas-catalog all 536 Disorders of function of stomach Digestive Both 1.11 0.98 1.26 0.0973 268 2666 FALSE 1.01188715973165 0.106 0.0641 0.157 0.195 0.419 1.17 0.798 1.72 0.463 0.184 0.0118 1.59 1.11 2.29 0.341 0.19 0.0736 1.41 0.968 2.06 ukb-melanoma-gwas-catalog all 536.8 Dyspepsia and other specified disorders of function of stomach Digestive Both 1.1 0.968 1.25 0.143 259 2576 FALSE 0.844663962534938 0.0955 0.0652 0.108 0.197 0.584 1.11 0.755 1.65 0.446 0.184 0.0157 1.56 1.09 2.26 0.265 0.193 0.171 1.3 0.891 1.91 ukb-melanoma-gwas-catalog all 537 Other disorders of stomach and duodenum Digestive Both 1.01 0.97 1.04 0.764 3400 33994 FALSE 0.11690664142431 0.00542 0.018 0.0924 0.0508 0.0693 1.1 0.993 1.21 0.0352 0.0516 0.494 1.04 0.936 1.15 0.042 0.0515 0.415 1.04 0.943 1.15 ukb-melanoma-gwas-catalog all 540 Appendiceal conditions Digestive Both 0.988 0.953 1.02 0.492 3409 34084 FALSE 0.30803489723264 -0.0124 0.018 -0.0018 0.0507 0.972 0.998 0.904 1.1 -0.00325 0.0507 0.949 0.997 0.902 1.1 -0.0329 0.0512 0.521 0.968 0.875 1.07 ukb-melanoma-gwas-catalog all 540.1 Appendicitis Digestive Both 0.988 0.952 1.02 0.5 3217 32164 FALSE 0.301029995663981 -0.0125 0.0186 -0.0146 0.0522 0.78 0.985 0.89 1.09 -0.00894 0.0521 0.864 0.991 0.895 1.1 -0.0366 0.0527 0.487 0.964 0.869 1.07 ukb-melanoma-gwas-catalog all 540.11 Acute appendicitis Digestive Both 0.985 0.946 1.03 0.456 2607 26064 FALSE 0.341035157335565 -0.0154 0.0206 -0.0187 0.0578 0.746 0.981 0.876 1.1 -0.0151 0.0578 0.794 0.985 0.879 1.1 -0.0532 0.0585 0.364 0.948 0.845 1.06 ukb-melanoma-gwas-catalog all 550 Abdominal hernia Digestive Both 1.01 1 1.02 0.0149 45931 283394 TRUE 1.82681373158773 0.0124 0.0051 0.00343 0.0144 0.812 1 0.975 1.03 -0.00702 0.0145 0.627 0.993 0.965 1.02 0.0249 0.0144 0.084 1.03 0.997 1.05 ukb-melanoma-gwas-catalog all 550.1 Inguinal hernia Digestive Both 0.996 0.98 1.01 0.674 15818 123480 FALSE 0.17134010346468 -0.00358 0.0085 -0.0254 0.0238 0.285 0.975 0.931 1.02 -0.0738 0.0241 0.00218 0.929 0.886 0.974 -0.0223 0.0239 0.35 0.978 0.933 1.02 ukb-melanoma-gwas-catalog all 550.2 Diaphragmatic hernia Digestive Both 1.02 1.01 1.04 0.000186 26560 239425 TRUE 3.73048705578208 0.0243 0.00649 0.0155 0.0185 0.401 1.02 0.979 1.05 0.0377 0.0184 0.041 1.04 1 1.08 0.0557 0.0184 0.00249 1.06 1.02 1.1 ukb-melanoma-gwas-catalog all 550.3 Femoral hernia Digestive Both 0.986 0.909 1.07 0.733 651 6510 FALSE 0.134896025358872 -0.0141 0.0412 0.0417 0.115 0.717 1.04 0.831 1.31 -0.0441 0.118 0.709 0.957 0.758 1.21 0.0185 0.116 0.873 1.02 0.811 1.28 ukb-melanoma-gwas-catalog all 550.4 Umbilical hernia Digestive Both 1.02 0.982 1.05 0.356 3713 37130 FALSE 0.448550002027125 0.0159 0.0172 -0.0266 0.0489 0.587 0.974 0.885 1.07 -0.000842 0.0486 0.986 0.999 0.908 1.1 0.00539 0.0486 0.912 1.01 0.914 1.11 ukb-melanoma-gwas-catalog all 550.5 Ventral hernia Digestive Both 1.03 0.994 1.07 0.11 3441 34410 FALSE 0.958607314841775 0.0287 0.0179 -0.0449 0.0509 0.377 0.956 0.865 1.06 -0.085 0.0514 0.0982 0.919 0.83 1.02 0.0739 0.0497 0.138 1.08 0.977 1.19 ukb-melanoma-gwas-catalog all 555 Inflammatory bowel disease and other gastroenteritis and colitis Digestive Both 0.987 0.957 1.02 0.396 4504 45040 FALSE 0.402304814074488 -0.0133 0.0157 -0.00565 0.0439 0.898 0.994 0.912 1.08 -0.0323 0.0443 0.465 0.968 0.888 1.06 -0.032 0.0444 0.47 0.968 0.888 1.06 ukb-melanoma-gwas-catalog all 555.1 Regional enteritis Digestive Both 0.973 0.926 1.02 0.281 1731 17310 FALSE 0.55129368009492 -0.0273 0.0253 -0.07 0.0704 0.32 0.932 0.812 1.07 -0.131 0.0714 0.0669 0.877 0.762 1.01 -0.0637 0.0705 0.367 0.938 0.817 1.08 ukb-melanoma-gwas-catalog all 555.2 Ulcerative colitis Digestive Both 0.99 0.954 1.03 0.58 3182 31820 FALSE 0.236572006437063 -0.0103 0.0187 0.0207 0.0522 0.692 1.02 0.921 1.13 -0.0173 0.0528 0.743 0.983 0.886 1.09 -0.0255 0.053 0.631 0.975 0.879 1.08 ukb-melanoma-gwas-catalog all 555.21 Ulcerative colitis (chronic) Digestive Both 1 0.919 1.1 0.913 538 5380 FALSE 0.039529222465701 0.00494 0.0452 0.058 0.126 0.646 1.06 0.827 1.36 -0.0898 0.13 0.491 0.914 0.707 1.18 0.053 0.127 0.676 1.05 0.822 1.35 ukb-melanoma-gwas-catalog all 556 Ulceration of the lower GI tract Digestive Both 0.982 0.922 1.05 0.578 1062 10620 FALSE 0.238072161579471 -0.018 0.0323 -0.0347 0.0909 0.703 0.966 0.808 1.15 -0.0452 0.0913 0.621 0.956 0.799 1.14 0.00087 0.0909 0.992 1 0.837 1.2 ukb-melanoma-gwas-catalog all 556.1 Ulceration of intestine Digestive Both 0.964 0.89 1.04 0.368 673 6730 FALSE 0.434152181326482 -0.0367 0.0407 0.00426 0.113 0.97 1 0.805 1.25 -0.0692 0.115 0.546 0.933 0.745 1.17 -0.047 0.115 0.682 0.954 0.761 1.2 ukb-melanoma-gwas-catalog all 557 Intestinal malabsorption (non-celiac) Digestive Both 1.03 0.911 1.16 0.67 301 3010 FALSE 0.173925197299174 0.0257 0.0603 0.0979 0.171 0.567 1.1 0.787 1.55 0.0936 0.171 0.584 1.1 0.784 1.54 0.0193 0.174 0.911 1.02 0.724 1.44 ukb-melanoma-gwas-catalog all 558 Noninfectious gastroenteritis Digestive Both 1.03 1.01 1.04 0.00301 15594 155922 TRUE 2.52143350440616 0.025 0.00842 -0.00838 0.0241 0.728 0.992 0.946 1.04 0.0494 0.0238 0.038 1.05 1 1.1 0.0479 0.0239 0.0446 1.05 1 1.1 ukb-melanoma-gwas-catalog all 559 Ileostomy status Digestive Both 0.976 0.928 1.03 0.35 1659 16590 FALSE 0.455931955649724 -0.0241 0.0258 0.00338 0.0726 0.963 1 0.87 1.16 0.0266 0.0723 0.712 1.03 0.891 1.18 -0.0569 0.0738 0.44 0.945 0.817 1.09 ukb-melanoma-gwas-catalog all 560 Intestinal obstruction without mention of hernia Digestive Both 1 0.969 1.03 0.952 4006 40053 FALSE 0.0213630516155257 0.001 0.0166 0.015 0.0471 0.75 1.02 0.926 1.11 0.0422 0.0469 0.368 1.04 0.952 1.14 0.0146 0.0473 0.757 1.01 0.925 1.11 ukb-melanoma-gwas-catalog all 560.1 Paralytic ileus Digestive Both 1.07 0.979 1.17 0.132 523 5230 FALSE 0.87942606879415 0.0691 0.0459 0.0627 0.135 0.642 1.06 0.817 1.39 0.185 0.132 0.161 1.2 0.929 1.56 0.241 0.131 0.0647 1.27 0.985 1.65 ukb-melanoma-gwas-catalog all 560.2 Impaction of intestine Digestive Both 0.963 0.849 1.09 0.55 268 2680 FALSE 0.259637310505756 -0.0382 0.0639 0.111 0.175 0.524 1.12 0.792 1.58 -0.21 0.189 0.267 0.811 0.557 1.18 0.0662 0.178 0.71 1.07 0.752 1.52 ukb-melanoma-gwas-catalog all 560.3 Peritoneal or intestinal adhesions Digestive Both 0.994 0.925 1.07 0.858 831 8310 FALSE 0.0665127121512946 -0.0065 0.0364 0.108 0.102 0.292 1.11 0.911 1.36 0.0576 0.104 0.578 1.06 0.864 1.3 0.0196 0.105 0.852 1.02 0.83 1.25 ukb-melanoma-gwas-catalog all 560.4 Other intestinal obstruction Digestive Both 0.992 0.957 1.03 0.641 3362 33616 FALSE 0.193141970481183 -0.00846 0.0181 0.0117 0.0512 0.82 1.01 0.915 1.12 0.038 0.0509 0.455 1.04 0.94 1.15 -0.0221 0.0519 0.669 0.978 0.884 1.08 ukb-melanoma-gwas-catalog all 561 Symptoms involving digestive system Digestive Both 1 0.983 1.02 0.969 15809 158086 FALSE 0.0136762229492347 -0.000324 0.00837 0.0174 0.0236 0.461 1.02 0.972 1.07 0.0136 0.0237 0.566 1.01 0.968 1.06 0.00593 0.0238 0.803 1.01 0.96 1.05 ukb-melanoma-gwas-catalog all 561.1 Diarrhea Digestive Both 1.03 0.936 1.13 0.548 466 4660 FALSE 0.261219441515631 0.0291 0.0485 -0.215 0.142 0.13 0.807 0.61 1.07 -0.0814 0.137 0.552 0.922 0.704 1.21 0.113 0.132 0.39 1.12 0.864 1.45 ukb-melanoma-gwas-catalog all 561.2 Flatulence Digestive Both 1.01 0.961 1.06 0.689 1688 16880 FALSE 0.161780778092374 0.0102 0.0256 0.0794 0.072 0.27 1.08 0.94 1.25 0.0283 0.0729 0.698 1.03 0.892 1.19 0.0206 0.0731 0.778 1.02 0.884 1.18 ukb-melanoma-gwas-catalog all 562 Diverticulosis and diverticulitis Digestive Both 1.01 1 1.03 0.0355 26751 211994 TRUE 1.44977164694491 0.0137 0.00653 0.0145 0.0186 0.434 1.01 0.978 1.05 0.0316 0.0185 0.0885 1.03 0.995 1.07 0.05 0.0185 0.00681 1.05 1.01 1.09 ukb-melanoma-gwas-catalog all 562.1 Diverticulosis Digestive Both 1.01 1 1.03 0.0369 26709 211935 TRUE 1.43297363384094 0.0136 0.00653 0.0148 0.0186 0.425 1.01 0.979 1.05 0.0325 0.0185 0.0793 1.03 0.996 1.07 0.0498 0.0185 0.00718 1.05 1.01 1.09 ukb-melanoma-gwas-catalog all 563 Constipation Digestive Both 0.99 0.97 1.01 0.32 10350 103421 FALSE 0.494850021680094 -0.0103 0.0103 -0.0406 0.0291 0.163 0.96 0.907 1.02 -0.0314 0.0291 0.28 0.969 0.915 1.03 -0.0346 0.0292 0.236 0.966 0.912 1.02 ukb-melanoma-gwas-catalog all 564 Functional digestive disorders Digestive Both 1.01 0.992 1.02 0.427 21783 210993 FALSE 0.369572124974976 0.00567 0.00714 0.0293 0.0202 0.147 1.03 0.99 1.07 0.0415 0.0202 0.04 1.04 1 1.08 0.0206 0.0204 0.311 1.02 0.981 1.06 ukb-melanoma-gwas-catalog all 564.1 Irritable Bowel Syndrome Digestive Both 1 0.975 1.03 0.842 5522 55220 FALSE 0.0746879085003505 0.00283 0.0142 0.0204 0.0401 0.612 1.02 0.943 1.1 0.0281 0.04 0.483 1.03 0.951 1.11 0.0175 0.0402 0.663 1.02 0.94 1.1 ukb-melanoma-gwas-catalog all 564.8 Abnormal findings on exam of gastrointestinal tract/ abdominal area Digestive Both 0.994 0.944 1.05 0.809 1649 16490 FALSE 0.0920514783877277 -0.00628 0.0259 -0.00529 0.0734 0.943 0.995 0.861 1.15 0.0368 0.0727 0.613 1.04 0.9 1.2 -0.00129 0.0736 0.986 0.999 0.864 1.15 ukb-melanoma-gwas-catalog all 564.9 Personal history of diseases of digestive system Digestive Both 1.01 0.991 1.02 0.383 15221 151974 FALSE 0.416801226031377 0.00745 0.00853 0.0381 0.0242 0.116 1.04 0.991 1.09 0.0482 0.0242 0.0462 1.05 1 1.1 0.0219 0.0244 0.368 1.02 0.975 1.07 ukb-melanoma-gwas-catalog all 565 Anal and rectal conditions Digestive Both 0.991 0.975 1.01 0.312 14862 148609 FALSE 0.505845405981557 -0.00872 0.00864 0.0111 0.0243 0.647 1.01 0.964 1.06 -0.0054 0.0244 0.825 0.995 0.948 1.04 -0.0176 0.0245 0.474 0.983 0.936 1.03 ukb-melanoma-gwas-catalog all 565.1 Anal and rectal polyp Digestive Both 0.984 0.961 1.01 0.194 7341 73408 FALSE 0.712198270069774 -0.0159 0.0123 0.00249 0.0344 0.942 1 0.937 1.07 -0.0408 0.0347 0.24 0.96 0.897 1.03 -0.0301 0.0348 0.387 0.97 0.906 1.04 ukb-melanoma-gwas-catalog all 567 Peritonitis and retroperitoneal infections Digestive Both 0.981 0.917 1.05 0.573 932 9320 FALSE 0.24184537803261 -0.0194 0.0345 0.205 0.0983 0.0365 1.23 1.01 1.49 0.25 0.0974 0.0102 1.28 1.06 1.56 0.0127 0.103 0.902 1.01 0.828 1.24 ukb-melanoma-gwas-catalog all 568 Other disorders of peritoneum Digestive Both 0.993 0.958 1.03 0.702 3309 33090 FALSE 0.153662887870195 -0.007 0.0183 0.0702 0.0511 0.17 1.07 0.97 1.19 0.00603 0.0519 0.907 1.01 0.909 1.11 -0.0341 0.0525 0.515 0.966 0.872 1.07 ukb-melanoma-gwas-catalog all 568.1 Peritoneal adhesions (postoperative) (postinfection) Digestive Both 0.985 0.949 1.02 0.417 3102 31020 FALSE 0.379863945026242 -0.0153 0.0189 0.0439 0.0527 0.405 1.04 0.942 1.16 -0.000896 0.0533 0.987 0.999 0.9 1.11 -0.0601 0.0541 0.267 0.942 0.847 1.05 ukb-melanoma-gwas-catalog all 569 Other disorders of intestine Digestive Both 1 0.973 1.04 0.809 4218 42180 FALSE 0.0920514783877277 0.0039 0.0162 -0.0419 0.0459 0.362 0.959 0.876 1.05 -0.0247 0.0458 0.59 0.976 0.892 1.07 0.027 0.0454 0.552 1.03 0.94 1.12 ukb-melanoma-gwas-catalog all 569.1 Toxic gastroenteritis and colitis Digestive Both 1.04 0.881 1.23 0.618 149 1490 FALSE 0.209011524911184 0.0425 0.0851 -0.0614 0.249 0.805 0.94 0.572 1.54 0.162 0.238 0.496 1.18 0.735 1.89 0.111 0.24 0.642 1.12 0.695 1.8 ukb-melanoma-gwas-catalog all 569.2 Gastrointestinal complications Digestive Both 0.959 0.873 1.05 0.384 484 4840 FALSE 0.415668775632469 -0.0416 0.0478 -0.117 0.131 0.373 0.89 0.687 1.15 -0.248 0.135 0.0662 0.78 0.597 1.02 -0.128 0.132 0.331 0.879 0.678 1.14 ukb-melanoma-gwas-catalog all 571 Chronic liver disease and cirrhosis Digestive Both 1.02 0.982 1.06 0.297 2984 29840 FALSE 0.527243550682788 0.0201 0.0193 0.0473 0.0547 0.387 1.05 0.942 1.17 0.0183 0.055 0.739 1.02 0.914 1.13 0.0724 0.0545 0.184 1.08 0.966 1.2 ukb-melanoma-gwas-catalog all 571.5 Other chronic nonalcoholic liver disease Digestive Both 1.01 0.956 1.06 0.834 1699 16990 FALSE 0.0788339493622613 0.00535 0.0255 0.0563 0.0723 0.436 1.06 0.918 1.22 0.0518 0.0724 0.474 1.05 0.914 1.21 0.043 0.0727 0.555 1.04 0.905 1.2 ukb-melanoma-gwas-catalog all 571.6 Primary biliary cirrhosis Digestive Both 1.05 0.925 1.2 0.443 256 2560 FALSE 0.35359627377693 0.0501 0.0653 -0.0901 0.189 0.634 0.914 0.628 1.33 -0.053 0.186 0.776 0.948 0.656 1.37 0.133 0.179 0.457 1.14 0.803 1.63 ukb-melanoma-gwas-catalog all 571.8 Liver abscess and sequelae of chronic liver disease Digestive Both 1.05 0.985 1.12 0.13 987 9870 FALSE 0.886056647693163 0.0507 0.0335 0.0397 0.0959 0.679 1.04 0.862 1.26 0.0371 0.096 0.699 1.04 0.86 1.25 0.126 0.0946 0.183 1.13 0.942 1.37 ukb-melanoma-gwas-catalog all 571.51 Cirrhosis of liver without mention of alcohol Digestive Both 0.753 0.618 0.916 0.0044 115 1150 TRUE 2.35654732351381 -0.284 0.0996 -0.194 0.248 0.434 0.824 0.502 1.34 -0.468 0.27 0.0824 0.626 0.363 1.06 -0.748 0.289 0.00971 0.474 0.262 0.831 ukb-melanoma-gwas-catalog all 571.81 Portal hypertension Digestive Both 1.06 0.97 1.16 0.195 532 5320 FALSE 0.709965388637482 0.059 0.0455 0.0202 0.129 0.876 1.02 0.791 1.32 -0.00814 0.13 0.95 0.992 0.768 1.28 0.0886 0.128 0.489 1.09 0.85 1.41 ukb-melanoma-gwas-catalog all 572 Ascites (non malignant) Digestive Both 1.01 0.954 1.06 0.836 1548 15480 FALSE 0.0777937225609836 0.00552 0.0267 -0.107 0.0758 0.157 0.898 0.774 1.04 -0.022 0.0744 0.768 0.978 0.845 1.13 -0.0489 0.075 0.514 0.952 0.822 1.1 ukb-melanoma-gwas-catalog all 573 Other disorders of liver Digestive Both 1.02 0.963 1.07 0.559 1505 15045 FALSE 0.252588192113577 0.0158 0.0271 -0.0512 0.077 0.507 0.95 0.817 1.11 0.016 0.0759 0.833 1.02 0.876 1.18 -0.0187 0.0766 0.807 0.981 0.844 1.14 ukb-melanoma-gwas-catalog all 573.5 Jaundice (not of newborn) Digestive Both 0.804 0.61 1.06 0.112 59 590 FALSE 0.950781977329818 -0.218 0.137 -0.413 0.365 0.258 0.662 0.313 1.36 -0.249 0.346 0.472 0.78 0.387 1.55 -0.766 0.403 0.0572 0.465 0.2 1.02 ukb-melanoma-gwas-catalog all 573.7 Abnormal results of function study of liver Digestive Both 0.98 0.83 1.16 0.807 156 1555 FALSE 0.0931264652779296 -0.0204 0.0836 -0.0427 0.24 0.859 0.958 0.594 1.54 -0.00657 0.236 0.978 0.993 0.622 1.59 0.108 0.232 0.642 1.11 0.704 1.77 ukb-melanoma-gwas-catalog all 574 Cholelithiasis and cholecystitis Digestive Both 1 0.986 1.02 0.759 16011 160020 FALSE 0.11975822410452 0.00255 0.00832 0.0165 0.0235 0.482 1.02 0.971 1.06 -0.00743 0.0236 0.753 0.993 0.948 1.04 0.0149 0.0235 0.526 1.02 0.969 1.06 ukb-melanoma-gwas-catalog all 574.1 Cholelithiasis Digestive Both 0.999 0.981 1.02 0.874 13618 136158 FALSE 0.058488567365597 -0.00143 0.00902 0.0164 0.0254 0.517 1.02 0.967 1.07 -0.0274 0.0256 0.285 0.973 0.925 1.02 0.0129 0.0255 0.612 1.01 0.964 1.06 ukb-melanoma-gwas-catalog all 574.2 Calculus of bile duct Digestive Both 0.993 0.953 1.03 0.721 2627 26264 FALSE 0.142064735280571 -0.00735 0.0206 0.0434 0.0576 0.452 1.04 0.933 1.17 0.00592 0.0581 0.919 1.01 0.898 1.13 -0.029 0.0587 0.622 0.971 0.866 1.09 ukb-melanoma-gwas-catalog all 574.3 Cholecystitis without cholelithiasis Digestive Both 1.01 0.971 1.05 0.615 2759 27590 FALSE 0.211124884224583 0.0101 0.02 0.0269 0.0567 0.635 1.03 0.919 1.15 0.048 0.0565 0.396 1.05 0.939 1.17 0.0162 0.0572 0.777 1.02 0.909 1.14 ukb-melanoma-gwas-catalog all 574.11 Cholelithiasis with acute cholecystitis Digestive Both 0.985 0.934 1.04 0.585 1511 15110 FALSE 0.23284413391782 -0.0148 0.027 -0.0476 0.0753 0.528 0.954 0.822 1.11 -0.117 0.0767 0.127 0.89 0.765 1.03 -0.0367 0.0755 0.627 0.964 0.831 1.12 ukb-melanoma-gwas-catalog all 574.12 Cholelithiasis with other cholecystitis Digestive Both 0.974 0.947 1 0.0691 5437 54370 FALSE 1.1605219526258 -0.026 0.0143 -0.0328 0.0399 0.41 0.968 0.895 1.05 -0.0512 0.0401 0.202 0.95 0.878 1.03 -0.0744 0.0404 0.0654 0.928 0.858 1 ukb-melanoma-gwas-catalog all 575 Other biliary tract disease Digestive Both 1.02 0.986 1.05 0.256 3897 38970 FALSE 0.59176003468815 0.0191 0.0168 0.0315 0.0477 0.51 1.03 0.94 1.13 0.0275 0.0478 0.566 1.03 0.936 1.13 0.0404 0.0478 0.397 1.04 0.948 1.14 ukb-melanoma-gwas-catalog all 575.1 Cholangitis Digestive Both 1.01 0.918 1.11 0.871 495 4950 FALSE 0.0599818449923368 0.00769 0.0472 -0.109 0.135 0.417 0.896 0.687 1.17 0.0258 0.131 0.843 1.03 0.793 1.33 -0.0144 0.132 0.913 0.986 0.76 1.28 ukb-melanoma-gwas-catalog all 575.2 Obstruction of bile duct Digestive Both 0.971 0.901 1.05 0.43 777 7770 FALSE 0.366531544420413 -0.0298 0.0377 -0.00586 0.105 0.955 0.994 0.809 1.22 -0.0346 0.106 0.743 0.966 0.785 1.19 -0.0764 0.107 0.477 0.926 0.75 1.14 ukb-melanoma-gwas-catalog all 575.6 Cholesterolosis of gallbladder Digestive Both 1.02 0.922 1.12 0.756 457 4570 FALSE 0.121478204498793 0.0153 0.049 0.0261 0.136 0.848 1.03 0.785 1.34 -0.115 0.141 0.413 0.891 0.675 1.18 0.0173 0.137 0.899 1.02 0.777 1.33 ukb-melanoma-gwas-catalog all 575.7 Other disorders of gallbladder Digestive Both 1.03 0.978 1.09 0.242 1410 14100 FALSE 0.616184634019569 0.0327 0.028 -0.0225 0.0794 0.776 0.978 0.837 1.14 -0.0294 0.0796 0.712 0.971 0.83 1.14 0.0482 0.0782 0.537 1.05 0.9 1.22 ukb-melanoma-gwas-catalog all 575.8 Other disorders of biliary tract Digestive Both 1.08 1.02 1.16 0.0134 1037 10370 TRUE 1.87289520163519 0.0805 0.0326 0.188 0.0945 0.0473 1.21 1 1.45 0.188 0.0947 0.0475 1.21 1 1.45 0.213 0.0943 0.0242 1.24 1.03 1.49 ukb-melanoma-gwas-catalog all 575.9 Nonspecific abnormal findings on radiological and other examination of biliary tract Digestive Both 0.976 0.873 1.09 0.659 349 3490 FALSE 0.18111458540599 -0.0248 0.0561 0.0177 0.16 0.912 1.02 0.742 1.4 0.226 0.154 0.143 1.25 0.926 1.7 -0.0994 0.165 0.547 0.905 0.653 1.25 ukb-melanoma-gwas-catalog all 577 Diseases of pancreas Digestive Both 1.01 0.972 1.05 0.563 2702 27020 FALSE 0.249491605148654 0.0117 0.0202 0.0301 0.0569 0.597 1.03 0.922 1.15 -0.00184 0.0574 0.974 0.998 0.892 1.12 0.00459 0.0576 0.936 1 0.897 1.12 ukb-melanoma-gwas-catalog all 577.1 Acute pancreatitis Digestive Both 1.01 0.969 1.06 0.533 1996 19960 FALSE 0.273272790973428 0.0147 0.0236 0.0137 0.066 0.836 1.01 0.891 1.15 -0.0619 0.0672 0.357 0.94 0.824 1.07 0.0186 0.0664 0.779 1.02 0.894 1.16 ukb-melanoma-gwas-catalog all 577.2 Chronic pancreatitis Digestive Both 1.07 0.973 1.17 0.167 514 5140 FALSE 0.777283528852417 0.0638 0.0462 -0.0314 0.134 0.814 0.969 0.745 1.26 0.0599 0.131 0.648 1.06 0.82 1.37 0.143 0.13 0.27 1.15 0.894 1.49 ukb-melanoma-gwas-catalog all 577.3 Cyst and pseudocyst of pancreas Digestive Both 0.936 0.839 1.04 0.233 363 3630 FALSE 0.632644078973981 -0.066 0.0553 -0.00776 0.152 0.959 0.992 0.736 1.34 -0.0214 0.152 0.888 0.979 0.726 1.32 -0.24 0.16 0.134 0.787 0.572 1.08 ukb-melanoma-gwas-catalog all 578 Gastrointestinal hemorrhage Digestive Both 1.01 0.991 1.02 0.451 20901 208958 FALSE 0.345823458122039 0.00549 0.00728 0.0142 0.0206 0.491 1.01 0.974 1.06 0.0215 0.0206 0.297 1.02 0.981 1.06 0.0124 0.0207 0.548 1.01 0.972 1.05 ukb-melanoma-gwas-catalog all 578.1 Hematemesis Digestive Both 1.02 0.974 1.07 0.396 1941 19396 FALSE 0.402304814074488 0.0202 0.0238 0.114 0.0679 0.092 1.12 0.981 1.28 0.117 0.0678 0.084 1.12 0.984 1.28 0.0607 0.0689 0.379 1.06 0.928 1.22 ukb-melanoma-gwas-catalog all 578.2 Blood in stool Digestive Both 0.993 0.953 1.03 0.721 2597 25956 FALSE 0.142064735280571 -0.00738 0.0207 -0.0688 0.0584 0.239 0.934 0.832 1.05 -0.0297 0.0579 0.608 0.971 0.866 1.09 -0.0204 0.058 0.725 0.98 0.874 1.1 ukb-melanoma-gwas-catalog all 578.8 Hemorrhage of rectum and anus Digestive Both 1.01 0.991 1.03 0.331 13031 130279 FALSE 0.480172006224281 0.00896 0.00922 0.0168 0.0261 0.519 1.02 0.966 1.07 0.0126 0.0261 0.629 1.01 0.962 1.07 0.0176 0.0261 0.501 1.02 0.967 1.07 ukb-melanoma-gwas-catalog all 578.9 Hemorrhage of gastrointestinal tract Digestive Both 1.01 0.98 1.04 0.586 5292 52920 FALSE 0.232102383981909 0.00789 0.0145 0.0237 0.0409 0.563 1.02 0.945 1.11 0.0277 0.0409 0.499 1.03 0.949 1.11 0.0233 0.0411 0.571 1.02 0.944 1.11 ukb-melanoma-gwas-catalog all 579 Other symptoms involving abdomen and pelvis Digestive Both 1.03 0.975 1.08 0.309 1553 15530 FALSE 0.510041520575165 0.0272 0.0267 -0.115 0.0767 0.135 0.892 0.767 1.04 0.0132 0.0745 0.859 1.01 0.875 1.17 0.0246 0.0746 0.741 1.02 0.885 1.19 ukb-melanoma-gwas-catalog all 579.2 Splenomegaly Digestive Both 1.04 0.943 1.15 0.42 426 4260 FALSE 0.3767507096021 0.041 0.0509 -0.00985 0.146 0.946 0.99 0.743 1.32 0.0636 0.144 0.659 1.07 0.803 1.42 0.101 0.144 0.482 1.11 0.834 1.47 ukb-melanoma-gwas-catalog all 580 Nephritis; nephrosis; renal sclerosis Genitourinary Both 1.03 0.974 1.08 0.336 1556 15560 FALSE 0.473660722610156 0.0256 0.0266 0.0354 0.0752 0.638 1.04 0.894 1.2 -0.0692 0.0772 0.37 0.933 0.802 1.09 0.103 0.0743 0.167 1.11 0.958 1.28 ukb-melanoma-gwas-catalog all 580.1 Glomerulonephritis Genitourinary Both 1.02 0.959 1.09 0.503 1069 10690 FALSE 0.298432014944073 0.0215 0.0321 0.128 0.0906 0.159 1.14 0.951 1.36 0.0292 0.0927 0.753 1.03 0.858 1.24 0.0865 0.0916 0.345 1.09 0.911 1.31 ukb-melanoma-gwas-catalog all 580.2 Nephrotic syndrome without mention of glomerulonephritis Genitourinary Both 1.03 0.932 1.13 0.609 469 4690 FALSE 0.215382707367125 0.0247 0.0484 -0.156 0.137 0.254 0.856 0.653 1.12 -0.218 0.139 0.117 0.804 0.61 1.06 0.0508 0.131 0.697 1.05 0.814 1.36 ukb-melanoma-gwas-catalog all 580.3 Nephritis and nephropathy without mention of glomerulonephritis Genitourinary Both 0.996 0.875 1.13 0.956 253 2530 FALSE 0.0195421077238999 -0.00362 0.0659 0.0843 0.183 0.645 1.09 0.759 1.56 -0.114 0.192 0.555 0.893 0.609 1.3 0.0949 0.183 0.605 1.1 0.766 1.58 ukb-melanoma-gwas-catalog all 580.11 Proliferative glomerulonephritis Genitourinary Both 0.973 0.77 1.23 0.816 79 790 FALSE 0.0883098412461389 -0.0272 0.117 0.131 0.334 0.694 1.14 0.585 2.24 0.158 0.325 0.626 1.17 0.612 2.26 0.0633 0.333 0.849 1.07 0.547 2.09 ukb-melanoma-gwas-catalog all 580.12 Non-proliferative glomerulonephritis Genitourinary Both 0.85 0.71 1.02 0.0722 136 1360 FALSE 1.14146280243036 -0.163 0.0907 0.169 0.23 0.463 1.18 0.753 1.87 -0.395 0.262 0.131 0.674 0.397 1.13 -0.393 0.264 0.137 0.675 0.396 1.14 ukb-melanoma-gwas-catalog all 580.14 Chronic glomerulonephritis, NOS Genitourinary Both 1.05 0.984 1.13 0.132 881 8810 FALSE 0.87942606879415 0.0532 0.0353 0.163 0.101 0.107 1.18 0.965 1.44 0.105 0.103 0.308 1.11 0.908 1.36 0.172 0.101 0.0904 1.19 0.973 1.45 ukb-melanoma-gwas-catalog all 580.32 Nephritis and nephropathy with pathological lesion Genitourinary Both 0.996 0.875 1.13 0.956 253 2530 FALSE 0.0195421077238999 -0.00362 0.0659 0.0843 0.183 0.645 1.09 0.759 1.56 -0.114 0.192 0.555 0.893 0.609 1.3 0.0949 0.183 0.605 1.1 0.766 1.58 ukb-melanoma-gwas-catalog all 585 Renal failure Genitourinary Both 1.01 0.984 1.03 0.504 7013 70119 FALSE 0.297569463554475 0.0084 0.0126 0.0357 0.0354 0.314 1.04 0.967 1.11 0.0257 0.0355 0.469 1.03 0.957 1.1 0.00136 0.0358 0.97 1 0.933 1.07 ukb-melanoma-gwas-catalog all 585.1 Acute renal failure Genitourinary Both 1 0.972 1.03 0.9 4537 45366 FALSE 0.0457574905606751 0.00197 0.0156 0.0072 0.044 0.87 1.01 0.924 1.1 0.0161 0.044 0.714 1.02 0.932 1.11 -0.0223 0.0445 0.617 0.978 0.896 1.07 ukb-melanoma-gwas-catalog all 585.2 Renal failure NOS Genitourinary Both 1.03 0.974 1.08 0.315 1466 14657 FALSE 0.501689446210399 0.0276 0.0274 0.0696 0.0775 0.369 1.07 0.921 1.25 0.0246 0.0784 0.754 1.02 0.879 1.2 0.0549 0.078 0.481 1.06 0.907 1.23 ukb-melanoma-gwas-catalog all 585.3 Chronic renal failure [CKD] Genitourinary Both 0.992 0.953 1.03 0.676 2652 26514 FALSE 0.170053304058364 -0.00853 0.0204 0.0347 0.057 0.542 1.04 0.926 1.16 -0.0277 0.0579 0.632 0.973 0.868 1.09 -0.0395 0.0581 0.497 0.961 0.858 1.08 ukb-melanoma-gwas-catalog all 585.31 Renal dialysis Genitourinary Both 1.04 0.948 1.14 0.408 494 4940 FALSE 0.38933983691012 0.0391 0.0473 0.186 0.135 0.17 1.2 0.923 1.57 0.118 0.137 0.389 1.13 0.86 1.48 0.164 0.136 0.229 1.18 0.902 1.54 ukb-melanoma-gwas-catalog all 586 Other disorders of the kidney and ureters Genitourinary Both 1.03 0.998 1.07 0.0648 3382 33819 FALSE 1.18842499412941 0.0334 0.0181 0.0423 0.0519 0.415 1.04 0.942 1.16 0.103 0.0513 0.0453 1.11 1 1.23 0.0895 0.0516 0.083 1.09 0.988 1.21 ukb-melanoma-gwas-catalog all 586.1 Anatomical abnormatilies of kidney and ureters Genitourinary Both 1.21 1.06 1.4 0.0065 215 2150 TRUE 2.18708664335714 0.195 0.0715 0.514 0.216 0.0175 1.67 1.1 2.58 0.395 0.223 0.0761 1.48 0.959 2.32 0.619 0.215 0.004 1.86 1.22 2.86 ukb-melanoma-gwas-catalog all 586.2 Cyst of kidney, acquired Genitourinary Both 1.01 0.949 1.07 0.831 1258 12579 FALSE 0.080398976215889 0.00633 0.0297 0.00889 0.0838 0.916 1.01 0.856 1.19 0.0238 0.0836 0.775 1.02 0.869 1.21 0.00935 0.0843 0.912 1.01 0.855 1.19 ukb-melanoma-gwas-catalog all 586.3 Vascular disorders of kidney/hypertrophy Genitourinary Both 1.24 0.988 1.57 0.0602 80 800 FALSE 1.22040350874218 0.218 0.116 0.208 0.356 0.56 1.23 0.602 2.56 0.33 0.353 0.349 1.39 0.689 2.88 0.696 0.335 0.0378 2.01 1.04 4.01 ukb-melanoma-gwas-catalog all 586.4 Stricture/obstruction of ureter Genitourinary Both 0.996 0.93 1.07 0.899 916 9160 FALSE 0.0462403082667712 -0.00439 0.0347 -0.0677 0.0983 0.491 0.935 0.77 1.13 -0.0171 0.0973 0.861 0.983 0.812 1.19 -0.00539 0.0975 0.956 0.995 0.821 1.2 ukb-melanoma-gwas-catalog all 586.11 Small kidney Genitourinary Both 1.22 1.04 1.42 0.0126 180 1800 TRUE 1.89962945488244 0.195 0.0781 0.448 0.235 0.0571 1.57 0.986 2.52 0.403 0.238 0.0901 1.5 0.938 2.42 0.571 0.233 0.0145 1.77 1.12 2.84 ukb-melanoma-gwas-catalog all 587 Kidney replaced by transpant Genitourinary Both 1.04 0.934 1.16 0.468 369 3690 FALSE 0.329754146925876 0.0395 0.0545 0.0727 0.156 0.64 1.08 0.792 1.46 -0.0713 0.161 0.659 0.931 0.677 1.28 0.243 0.151 0.106 1.28 0.949 1.72 ukb-melanoma-gwas-catalog all 588 Disorders resulting from impaired renal function Genitourinary Both 1.11 0.903 1.36 0.314 99 990 FALSE 0.503070351926785 0.104 0.104 -0.481 0.334 0.149 0.618 0.311 1.2 0.259 0.286 0.364 1.3 0.737 2.31 0.239 0.288 0.406 1.27 0.719 2.27 ukb-melanoma-gwas-catalog all 589 Abnormal results of function study of kidney Genitourinary Both 0.986 0.813 1.19 0.883 117 1170 FALSE 0.0540392964224314 -0.0143 0.097 -0.219 0.276 0.426 0.803 0.461 1.39 0.0352 0.267 0.895 1.04 0.608 1.76 -0.00129 0.269 0.996 0.999 0.584 1.71 ukb-melanoma-gwas-catalog all 590 Pyelonephritis Genitourinary Both 0.96 0.907 1.02 0.157 1331 13310 FALSE 0.804100347590766 -0.0408 0.0288 0.0495 0.0798 0.535 1.05 0.898 1.23 -0.0577 0.0819 0.481 0.944 0.804 1.11 -0.052 0.0819 0.525 0.949 0.808 1.11 ukb-melanoma-gwas-catalog all 591 Urinary tract infection Genitourinary Both 1 0.985 1.02 0.735 12432 124264 FALSE 0.133712660915805 0.0032 0.00944 -0.0125 0.0267 0.638 0.988 0.937 1.04 -0.0145 0.0267 0.587 0.986 0.935 1.04 0.00675 0.0266 0.8 1.01 0.956 1.06 ukb-melanoma-gwas-catalog all 592 Cystitis and urethritis Genitourinary Both 1.02 0.979 1.05 0.396 3076 30754 FALSE 0.402304814074488 0.0161 0.019 -0.0185 0.0538 0.731 0.982 0.883 1.09 0.00862 0.0535 0.872 1.01 0.908 1.12 0.0167 0.0536 0.756 1.02 0.915 1.13 ukb-melanoma-gwas-catalog all 592.1 Cystitis Genitourinary Both 1.02 0.98 1.06 0.353 2936 29354 FALSE 0.452225294612177 0.018 0.0194 -0.0302 0.0551 0.584 0.97 0.871 1.08 -0.00523 0.0548 0.924 0.995 0.893 1.11 0.0216 0.0547 0.693 1.02 0.918 1.14 ukb-melanoma-gwas-catalog all 592.2 Urethritis and urethral syndrome Genitourinary Both 0.939 0.8 1.1 0.439 167 1670 FALSE 0.357535479757879 -0.0628 0.0811 0.335 0.223 0.134 1.4 0.901 2.19 0.229 0.227 0.313 1.26 0.804 1.98 -0.228 0.25 0.363 0.796 0.482 1.31 ukb-melanoma-gwas-catalog all 592.11 Acute cystitis Genitourinary Both 1.03 0.86 1.22 0.77 137 1370 FALSE 0.113509274827518 0.0259 0.0887 -0.449 0.26 0.0833 0.638 0.377 1.06 -0.434 0.257 0.092 0.648 0.385 1.07 0.0806 0.227 0.722 1.08 0.693 1.7 ukb-melanoma-gwas-catalog all 592.12 Chronic cystitis Genitourinary Both 1.01 0.945 1.08 0.73 889 8890 FALSE 0.136677139879544 0.0122 0.0352 -0.0977 0.101 0.331 0.907 0.744 1.1 0.00558 0.0983 0.955 1.01 0.829 1.22 -0.00447 0.0988 0.964 0.996 0.82 1.21 ukb-melanoma-gwas-catalog all 592.13 Chronic interstitial cystitis Genitourinary Both 0.966 0.847 1.1 0.604 247 2470 FALSE 0.218963061378868 -0.0346 0.0667 0.125 0.183 0.494 1.13 0.79 1.63 0.0516 0.186 0.782 1.05 0.729 1.52 -0.133 0.196 0.496 0.875 0.593 1.29 ukb-melanoma-gwas-catalog all 593 Hematuria Genitourinary Both 1.01 0.992 1.02 0.343 16202 161323 FALSE 0.464705879957229 0.00785 0.00827 0.0234 0.0234 0.316 1.02 0.978 1.07 0.000332 0.0235 0.989 1 0.955 1.05 0.0356 0.0234 0.128 1.04 0.99 1.08 ukb-melanoma-gwas-catalog all 594 Urinary calculus Genitourinary Both 1.01 0.988 1.04 0.313 6612 66119 FALSE 0.504455662453552 0.013 0.0129 0.0131 0.0366 0.72 1.01 0.943 1.09 -0.0105 0.0368 0.774 0.99 0.921 1.06 0.0266 0.0365 0.467 1.03 0.956 1.1 ukb-melanoma-gwas-catalog all 594.1 Calculus of kidney Genitourinary Both 1 0.964 1.04 0.992 3176 31760 FALSE 0.00348832784582135 -0.000179 0.0187 0.0076 0.0523 0.885 1.01 0.909 1.12 -0.0378 0.0529 0.475 0.963 0.868 1.07 -0.0192 0.0528 0.716 0.981 0.885 1.09 ukb-melanoma-gwas-catalog all 594.2 Calculus of lower urinary tract Genitourinary Both 1.03 0.956 1.11 0.434 776 7760 FALSE 0.362510270487489 0.0295 0.0377 -0.0314 0.107 0.769 0.969 0.785 1.2 -0.0531 0.107 0.621 0.948 0.768 1.17 0.0497 0.105 0.637 1.05 0.855 1.29 ukb-melanoma-gwas-catalog all 594.3 Calculus of ureter Genitourinary Both 1 0.961 1.05 0.922 2403 24029 FALSE 0.0352690789463706 0.0021 0.0214 0.0511 0.06 0.395 1.05 0.936 1.18 -0.0447 0.0614 0.467 0.956 0.848 1.08 0.0243 0.0606 0.689 1.02 0.91 1.15 ukb-melanoma-gwas-catalog all 594.8 Renal colic Genitourinary Both 1.01 0.962 1.05 0.775 2045 20449 FALSE 0.11069829749369 0.00666 0.0233 0.000307 0.0658 0.996 1 0.879 1.14 0.0075 0.0657 0.909 1.01 0.886 1.15 0.00388 0.066 0.953 1 0.882 1.14 ukb-melanoma-gwas-catalog all 595 Hydronephrosis Genitourinary Both 0.952 0.908 0.997 0.0377 1953 19530 TRUE 1.42365864979421 -0.0496 0.0239 -0.0578 0.0655 0.378 0.944 0.83 1.07 -0.158 0.0671 0.0183 0.854 0.748 0.974 -0.125 0.0667 0.0605 0.882 0.774 1.01 ukb-melanoma-gwas-catalog all 596 Other disorders of bladder Genitourinary Both 1 0.982 1.02 0.81 9856 98560 FALSE 0.0915149811213502 0.00255 0.0106 0.0153 0.0299 0.608 1.02 0.958 1.08 0.0195 0.0299 0.515 1.02 0.962 1.08 -0.00301 0.0302 0.92 0.997 0.94 1.06 ukb-melanoma-gwas-catalog all 596.1 Bladder neck obstruction Genitourinary Both 1.03 0.982 1.08 0.229 1963 19630 FALSE 0.640164517660112 0.0285 0.0237 -0.0323 0.0673 0.632 0.968 0.848 1.1 -0.0212 0.0671 0.752 0.979 0.858 1.12 0.0192 0.0667 0.773 1.02 0.894 1.16 ukb-melanoma-gwas-catalog all 596.5 Functional disorders of bladder Genitourinary Both 0.995 0.946 1.05 0.839 1653 16530 FALSE 0.0762380391712997 -0.00525 0.0259 0.102 0.0727 0.159 1.11 0.961 1.28 0.0709 0.0733 0.334 1.07 0.93 1.24 -0.0066 0.0748 0.93 0.993 0.858 1.15 ukb-melanoma-gwas-catalog all 597 Other disorders of urethra and urinary tract Genitourinary Both 0.987 0.956 1.02 0.445 3984 39834 FALSE 0.351639989019068 -0.0127 0.0167 -0.0437 0.0471 0.353 0.957 0.873 1.05 -0.0171 0.0469 0.715 0.983 0.897 1.08 -0.013 0.047 0.782 0.987 0.9 1.08 ukb-melanoma-gwas-catalog all 597.1 Urethral stricture (not specified as infectious) Genitourinary Both 0.983 0.948 1.02 0.338 3322 33214 FALSE 0.471083299722345 -0.0175 0.0183 -0.0416 0.0514 0.419 0.959 0.867 1.06 -0.0275 0.0513 0.592 0.973 0.88 1.08 -0.0264 0.0515 0.608 0.974 0.88 1.08 ukb-melanoma-gwas-catalog all 598 Abnormal findings on examination of urine Genitourinary Both 0.996 0.962 1.03 0.799 3538 35378 FALSE 0.0974532206860086 -0.0045 0.0177 -0.0177 0.0496 0.722 0.983 0.891 1.08 -0.034 0.0498 0.494 0.967 0.877 1.07 -0.0387 0.0501 0.439 0.962 0.872 1.06 ukb-melanoma-gwas-catalog all 598.9 Other nonspecific findings on examination of urine Genitourinary Both 1.03 0.912 1.16 0.662 304 3040 FALSE 0.1791420105603 0.0263 0.0601 -0.0386 0.172 0.823 0.962 0.685 1.35 0.168 0.165 0.31 1.18 0.855 1.64 -0.0259 0.173 0.881 0.974 0.692 1.37 ukb-melanoma-gwas-catalog all 599 Other symptoms/disorders or the urinary system Genitourinary Both 0.99 0.975 1 0.174 18729 187237 FALSE 0.7594507517174 -0.0105 0.00769 0.0219 0.0216 0.31 1.02 0.98 1.07 0.00674 0.0217 0.756 1.01 0.965 1.05 -0.0248 0.0219 0.258 0.976 0.934 1.02 ukb-melanoma-gwas-catalog all 599.1 Urinary obstruction Genitourinary Both 0.924 0.788 1.08 0.329 167 1670 FALSE 0.482804102050026 -0.0789 0.0808 -0.0681 0.221 0.758 0.934 0.602 1.45 -0.109 0.224 0.626 0.896 0.574 1.4 -0.225 0.229 0.326 0.798 0.505 1.25 ukb-melanoma-gwas-catalog all 599.2 Retention of urine Genitourinary Both 1.01 0.981 1.03 0.62 6733 67330 FALSE 0.207608310501746 0.00635 0.0128 0.000147 0.0362 0.997 1 0.932 1.07 -0.0147 0.0363 0.685 0.985 0.918 1.06 0.0186 0.0362 0.607 1.02 0.949 1.09 ukb-melanoma-gwas-catalog all 599.3 Dysuria Genitourinary Both 1.02 0.959 1.08 0.557 1199 11990 FALSE 0.254144804826271 0.0178 0.0304 0.21 0.0861 0.0149 1.23 1.04 1.46 0.0931 0.0881 0.291 1.1 0.923 1.31 0.125 0.0881 0.157 1.13 0.953 1.35 ukb-melanoma-gwas-catalog all 599.4 Urinary incontinence Genitourinary Both 0.981 0.96 1 0.0967 8766 87659 FALSE 1.014573525917 -0.0187 0.0112 0.00691 0.0315 0.826 1.01 0.947 1.07 -0.0109 0.0317 0.73 0.989 0.93 1.05 -0.0453 0.032 0.157 0.956 0.898 1.02 ukb-melanoma-gwas-catalog all 599.5 Frequency of urination and polyuria Genitourinary Both 0.987 0.955 1.02 0.415 4023 40230 FALSE 0.381951903287907 -0.0135 0.0166 0.0362 0.0468 0.439 1.04 0.946 1.14 0.0571 0.0466 0.22 1.06 0.966 1.16 -0.0273 0.0477 0.566 0.973 0.886 1.07 ukb-melanoma-gwas-catalog all 599.6 Oliguria and anuria Genitourinary Both 0.991 0.812 1.21 0.932 107 1070 FALSE 0.0305840876460186 -0.00859 0.1 -0.342 0.297 0.249 0.71 0.388 1.28 0.21 0.263 0.424 1.23 0.734 2.09 -0.145 0.285 0.611 0.865 0.487 1.52 ukb-melanoma-gwas-catalog all 599.8 Other symptoms involving urinary system Genitourinary Both 1.13 0.903 1.4 0.284 87 870 FALSE 0.546681659952962 0.119 0.111 0.414 0.33 0.209 1.51 0.789 2.97 0.409 0.324 0.206 1.51 0.795 2.92 0.368 0.332 0.268 1.44 0.747 2.85 ukb-melanoma-gwas-catalog all 599.9 Other abnormality of urination Genitourinary Both 0.994 0.949 1.04 0.811 1921 19210 FALSE 0.0909791457888439 -0.00575 0.024 -0.0199 0.0679 0.77 0.98 0.858 1.12 0.0101 0.0676 0.881 1.01 0.885 1.15 0.0016 0.0678 0.981 1 0.877 1.14 ukb-melanoma-gwas-catalog all 600 Hyperplasia of prostate Genitourinary Male 0.998 0.978 1.02 0.829 11123 87742 FALSE 0.0814454694497265 -0.00219 0.0101 -0.0337 0.0286 0.24 0.967 0.914 1.02 -0.0182 0.0286 0.524 0.982 0.928 1.04 -0.00512 0.0286 0.858 0.995 0.941 1.05 ukb-melanoma-gwas-catalog all 601 Inflammatory diseases of prostate Genitourinary Male 1.01 0.969 1.06 0.584 2188 21880 FALSE 0.233587152887601 0.0123 0.0225 0.0487 0.0634 0.443 1.05 0.927 1.19 -0.00651 0.0642 0.919 0.994 0.876 1.13 0.0328 0.0637 0.606 1.03 0.912 1.17 ukb-melanoma-gwas-catalog all 601.1 Prostatitis Genitourinary Male 1.01 0.961 1.07 0.66 1576 15760 FALSE 0.180456064458131 0.0116 0.0265 -0.0043 0.0751 0.954 0.996 0.859 1.15 -0.0143 0.0752 0.849 0.986 0.851 1.14 0.0411 0.0744 0.58 1.04 0.901 1.21 ukb-melanoma-gwas-catalog all 601.3 Orchitis and epididymitis Genitourinary Male 1.06 0.804 1.38 0.688 59 590 FALSE 0.162411561764489 0.0543 0.135 0.627 0.391 0.109 1.87 0.87 4.25 0.373 0.414 0.368 1.45 0.638 3.42 0.247 0.417 0.554 1.28 0.555 3.04 ukb-melanoma-gwas-catalog all 601.4 Balanoposthitis Genitourinary Male 0.962 0.851 1.09 0.534 286 2860 FALSE 0.272458742971444 -0.0387 0.0622 0.238 0.17 0.161 1.27 0.909 1.78 -0.0123 0.179 0.945 0.988 0.694 1.41 -0.0444 0.181 0.806 0.957 0.669 1.37 ukb-melanoma-gwas-catalog all 601.8 Other inflammatory disorders of male genital organs Genitourinary Male 1.08 0.959 1.21 0.203 303 3030 FALSE 0.692503962086787 0.0764 0.06 0.154 0.171 0.367 1.17 0.834 1.64 0.0174 0.176 0.921 1.02 0.719 1.44 0.141 0.171 0.411 1.15 0.822 1.62 ukb-melanoma-gwas-catalog all 601.11 Acute prostatitis Genitourinary Male 0.959 0.838 1.1 0.539 235 2350 FALSE 0.268411234813261 -0.0419 0.0681 0.0363 0.191 0.849 1.04 0.712 1.51 0.0403 0.191 0.833 1.04 0.714 1.52 -0.0668 0.196 0.734 0.935 0.634 1.38 ukb-melanoma-gwas-catalog all 601.12 Chronic prostatitis Genitourinary Male 1.05 0.983 1.13 0.141 910 9100 FALSE 0.85078088734462 0.0513 0.0348 -0.053 0.0998 0.595 0.948 0.779 1.15 -0.0065 0.0987 0.947 0.994 0.818 1.21 0.0748 0.0972 0.442 1.08 0.891 1.3 ukb-melanoma-gwas-catalog all 602 Other disorders of prostate Genitourinary Male 0.987 0.933 1.04 0.639 1343 13430 FALSE 0.1944991418416 -0.0135 0.0287 0.105 0.0805 0.191 1.11 0.949 1.3 0.00374 0.0824 0.964 1 0.854 1.18 0.0354 0.0819 0.666 1.04 0.882 1.22 ukb-melanoma-gwas-catalog all 603 Other disorders of testis Genitourinary Male 1.01 0.969 1.06 0.585 2192 21912 FALSE 0.23284413391782 0.0123 0.0225 -0.0273 0.063 0.665 0.973 0.86 1.1 -0.0597 0.0637 0.349 0.942 0.831 1.07 -0.0157 0.063 0.803 0.984 0.87 1.11 ukb-melanoma-gwas-catalog all 603.1 Hydrocele Genitourinary Male 1.01 0.956 1.07 0.685 1340 13400 FALSE 0.164309428507574 0.0116 0.0287 0.021 0.0806 0.795 1.02 0.872 1.2 -0.0397 0.0819 0.628 0.961 0.818 1.13 0.0196 0.0809 0.808 1.02 0.87 1.2 ukb-melanoma-gwas-catalog all 604 Disorders of penis Genitourinary Male 1.02 0.986 1.06 0.229 3412 34093 FALSE 0.640164517660112 0.0217 0.018 0.104 0.0512 0.0426 1.11 1 1.23 0.0902 0.0515 0.0799 1.09 0.989 1.21 0.078 0.0518 0.132 1.08 0.977 1.2 ukb-melanoma-gwas-catalog all 604.1 Redundant prepuce and phimosis/BXO Genitourinary Male 1.02 0.981 1.06 0.322 2853 28505 FALSE 0.492144128304169 0.0195 0.0197 0.123 0.0559 0.0276 1.13 1.01 1.26 0.0942 0.0564 0.0948 1.1 0.984 1.23 0.068 0.0569 0.232 1.07 0.957 1.2 ukb-melanoma-gwas-catalog all 605 Erectile dysfunction [ED] Genitourinary Male 1.1 0.969 1.24 0.143 280 2800 FALSE 0.844663962534938 0.092 0.0628 -0.209 0.188 0.265 0.811 0.559 1.17 0.124 0.174 0.478 1.13 0.803 1.6 0.132 0.174 0.449 1.14 0.81 1.61 ukb-melanoma-gwas-catalog all 608 Other disorders of male genital organs Genitourinary Male 1.01 0.971 1.05 0.647 2826 28259 FALSE 0.1890957193313 0.00907 0.0198 0.0758 0.0561 0.176 1.08 0.966 1.2 0.0814 0.056 0.146 1.08 0.972 1.21 0.0189 0.057 0.74 1.02 0.911 1.14 ukb-melanoma-gwas-catalog all 609 Male infertility and abnormal spermatozoa Genitourinary Male 0.986 0.861 1.13 0.837 233 2330 FALSE 0.07727454200674 -0.0142 0.0687 0.558 0.193 0.00374 1.75 1.2 2.57 0.0616 0.213 0.772 1.06 0.698 1.62 0.22 0.205 0.284 1.25 0.832 1.87 ukb-melanoma-gwas-catalog all 609.1 Infertility, male Genitourinary Male 0.763 0.584 0.99 0.0409 64 640 TRUE 1.38827669199266 -0.271 0.133 0.0431 0.323 0.894 1.04 0.549 1.99 -0.772 0.398 0.0522 0.462 0.199 1 -0.462 0.365 0.206 0.63 0.298 1.29 ukb-melanoma-gwas-catalog all 609.2 Abnormal spermatozoa Genitourinary Male 1.1 0.938 1.29 0.242 170 1700 FALSE 0.616184634019569 0.0936 0.08 0.822 0.247 0.00086 2.27 1.41 3.76 0.526 0.258 0.0416 1.69 1.02 2.86 0.6 0.255 0.0185 1.82 1.11 3.06 ukb-melanoma-gwas-catalog all 610 Benign mammary dysplasias Genitourinary Female 1.04 1 1.08 0.0495 2838 28379 TRUE 1.30539480106643 0.0388 0.0197 0.0681 0.0567 0.23 1.07 0.958 1.2 0.124 0.0561 0.0268 1.13 1.01 1.26 0.092 0.0566 0.104 1.1 0.981 1.23 ukb-melanoma-gwas-catalog all 610.1 Cystic mastopathy Genitourinary Female 1.05 0.979 1.12 0.174 923 9229 FALSE 0.7594507517174 0.0469 0.0345 0.191 0.0998 0.0558 1.21 0.995 1.47 0.173 0.1 0.0844 1.19 0.977 1.45 0.193 0.1 0.0535 1.21 0.997 1.48 ukb-melanoma-gwas-catalog all 610.2 Fibroadenosis of breast Genitourinary Female 1.14 1.01 1.28 0.0282 306 3060 TRUE 1.54975089168064 0.132 0.06 0.0416 0.188 0.824 1.04 0.719 1.51 0.527 0.171 0.00201 1.69 1.21 2.38 0.285 0.177 0.108 1.33 0.939 1.89 ukb-melanoma-gwas-catalog all 610.3 Fibrosclerosis of breast Genitourinary Female 1.05 0.935 1.19 0.389 301 3010 FALSE 0.410050398674292 0.052 0.0603 0.0507 0.176 0.773 1.05 0.744 1.49 0.185 0.171 0.279 1.2 0.86 1.69 0.148 0.173 0.395 1.16 0.824 1.63 ukb-melanoma-gwas-catalog all 610.4 Benign neoplasm of breast Genitourinary Female 1.02 0.972 1.08 0.373 1548 15479 FALSE 0.428291168191312 0.0238 0.0267 -0.0296 0.0759 0.696 0.971 0.836 1.13 0.0518 0.0748 0.488 1.05 0.91 1.22 -0.0187 0.0761 0.806 0.981 0.845 1.14 ukb-melanoma-gwas-catalog all 610.8 Other specified benign mammary dysplasias Genitourinary Female 1.05 0.896 1.23 0.532 165 1650 FALSE 0.274088367704952 0.0507 0.0811 -0.107 0.237 0.652 0.899 0.56 1.44 0.0428 0.229 0.852 1.04 0.663 1.65 0.129 0.225 0.568 1.14 0.729 1.78 ukb-melanoma-gwas-catalog all 611 Abnormal findings on mammogram or breast exam Genitourinary Both 1.04 0.987 1.1 0.138 1578 15780 FALSE 0.860120913598763 0.0392 0.0264 0.104 0.0748 0.166 1.11 0.958 1.28 0.0184 0.0763 0.809 1.02 0.877 1.18 0.0823 0.0753 0.274 1.09 0.937 1.26 ukb-melanoma-gwas-catalog all 611.1 Abnormal mammogram Genitourinary Both 1.3 0.999 1.7 0.0466 57 570 TRUE 1.33161408331 0.266 0.134 0.55 0.407 0.177 1.73 0.775 4.1 0.295 0.423 0.485 1.34 0.574 3.26 0.639 0.403 0.113 1.89 0.857 4.44 ukb-melanoma-gwas-catalog all 611.3 Lump or mass in breast Genitourinary Both 1.03 0.979 1.09 0.245 1523 15230 FALSE 0.610833915635468 0.0313 0.0269 0.0976 0.076 0.199 1.1 0.95 1.28 0.0191 0.0774 0.805 1.02 0.876 1.19 0.0689 0.0767 0.369 1.07 0.922 1.25 ukb-melanoma-gwas-catalog all 612 Breast conditions, congenital or relating to hormones Genitourinary Both 0.961 0.898 1.03 0.242 939 9390 FALSE 0.616184634019569 -0.0401 0.0343 -0.0727 0.095 0.444 0.93 0.771 1.12 -0.0624 0.0949 0.511 0.94 0.78 1.13 -0.191 0.0978 0.0512 0.826 0.682 1 ukb-melanoma-gwas-catalog all 612.2 Hypertrophy of breast (Gynecomastia) Genitourinary Both 0.971 0.905 1.04 0.412 851 8510 FALSE 0.385102783966865 -0.0296 0.036 -0.0274 0.1 0.785 0.973 0.799 1.18 -0.00686 0.0999 0.945 0.993 0.816 1.21 -0.142 0.103 0.169 0.868 0.708 1.06 ukb-melanoma-gwas-catalog all 612.3 Congenital anomalies of breast Genitourinary Both 0.894 0.707 1.13 0.344 78 780 FALSE 0.46344155742847 -0.112 0.118 -0.401 0.312 0.198 0.67 0.356 1.23 -0.58 0.326 0.0753 0.56 0.286 1.06 -0.479 0.316 0.13 0.619 0.325 1.15 ukb-melanoma-gwas-catalog all 613 Other nonmalignant breast conditions Genitourinary Both 1.08 1.03 1.13 0.00067 1981 19796 TRUE 3.17392519729917 0.0803 0.0236 0.192 0.0686 0.005 1.21 1.06 1.39 0.184 0.0687 0.0075 1.2 1.05 1.38 0.218 0.0685 0.0015 1.24 1.09 1.42 ukb-melanoma-gwas-catalog all 613.1 Inflammatory disease of breast Genitourinary Both 1.08 0.997 1.16 0.0581 721 7205 FALSE 1.23582386760967 0.0742 0.0392 0.226 0.113 0.0456 1.25 1 1.57 0.154 0.115 0.179 1.17 0.931 1.46 0.235 0.113 0.0385 1.26 1.01 1.58 ukb-melanoma-gwas-catalog all 613.5 Mastodynia Genitourinary Both 1.09 0.865 1.38 0.448 77 770 FALSE 0.348721986001856 0.0898 0.118 -0.0518 0.335 0.877 0.949 0.483 1.86 -0.129 0.34 0.704 0.879 0.442 1.74 0.18 0.326 0.58 1.2 0.629 2.31 ukb-melanoma-gwas-catalog all 613.7 Other signs and symptoms in breast Genitourinary Both 1.09 1.01 1.18 0.0292 704 7031 TRUE 1.53461714855158 0.0863 0.0396 0.232 0.115 0.0431 1.26 1.01 1.58 0.209 0.116 0.0704 1.23 0.983 1.55 0.23 0.115 0.0463 1.26 1 1.58 ukb-melanoma-gwas-catalog all 613.8 Other specified disorders of breast Genitourinary Both 1.1 0.986 1.24 0.0852 328 3280 FALSE 1.0695604052333 0.0996 0.0579 0.447 0.171 0.00893 1.56 1.12 2.2 0.346 0.176 0.0492 1.41 1 2.01 0.401 0.174 0.0208 1.49 1.06 2.11 ukb-melanoma-gwas-catalog all 613.9 Breast disorder NOS Genitourinary Both 1.06 0.921 1.23 0.399 207 2070 FALSE 0.399027104313252 0.0612 0.0726 -0.148 0.209 0.479 0.862 0.568 1.3 0.0939 0.199 0.637 1.1 0.742 1.63 -0.00648 0.205 0.975 0.994 0.662 1.49 ukb-melanoma-gwas-catalog all 614 Inflammatory diseases of female pelvic organs Genitourinary Female 1.02 0.989 1.04 0.264 6180 61800 FALSE 0.578396073130169 0.015 0.0134 0.00891 0.0379 0.814 1.01 0.937 1.09 -0.00792 0.0381 0.835 0.992 0.921 1.07 0.0345 0.0378 0.361 1.04 0.961 1.11 ukb-melanoma-gwas-catalog all 614.1 Pelvic peritoneal adhesions, female (postoperative) (postinfection) Genitourinary Female 1.04 0.999 1.08 0.0562 2538 25380 FALSE 1.25026368443094 0.0398 0.0209 -0.0449 0.0599 0.453 0.956 0.85 1.08 0.0206 0.0592 0.728 1.02 0.909 1.15 0.0666 0.0585 0.255 1.07 0.953 1.2 ukb-melanoma-gwas-catalog all 614.3 Pelvic inflammatory disease (PID) Genitourinary Female 0.987 0.923 1.06 0.707 934 9340 FALSE 0.150580586203101 -0.0129 0.0344 -0.028 0.0967 0.772 0.972 0.804 1.18 -0.0287 0.0968 0.767 0.972 0.803 1.18 -0.019 0.0971 0.845 0.981 0.811 1.19 ukb-melanoma-gwas-catalog all 614.4 Inflammatory diseases of uterus, except cervix Genitourinary Female 0.913 0.807 1.03 0.15 278 2780 FALSE 0.823908740944319 -0.0906 0.063 -0.203 0.172 0.236 0.816 0.581 1.14 -0.211 0.173 0.222 0.81 0.576 1.14 -0.27 0.177 0.127 0.763 0.537 1.08 ukb-melanoma-gwas-catalog all 614.5 Inflammatory disease of cervix, vagina, and vulva Genitourinary Female 1.01 0.972 1.05 0.586 2850 28500 FALSE 0.232102383981909 0.0108 0.0197 0.056 0.0556 0.314 1.06 0.948 1.18 0.00256 0.0564 0.964 1 0.897 1.12 0.0475 0.0559 0.396 1.05 0.94 1.17 ukb-melanoma-gwas-catalog all 614.31 Acute inflammatory pelvic disease Genitourinary Female 0.962 0.736 1.25 0.771 61 610 FALSE 0.112945621949043 -0.0388 0.133 -0.681 0.386 0.0775 0.506 0.227 1.08 -0.278 0.349 0.426 0.758 0.373 1.51 -0.337 0.354 0.342 0.714 0.348 1.44 ukb-melanoma-gwas-catalog all 614.32 Chronic inflammatory pelvic disease Genitourinary Female 0.954 0.863 1.06 0.36 422 4220 FALSE 0.443697499232713 -0.0468 0.0512 -0.092 0.142 0.518 0.912 0.689 1.21 -0.0741 0.142 0.602 0.929 0.702 1.23 -0.107 0.144 0.456 0.898 0.676 1.19 ukb-melanoma-gwas-catalog all 614.33 Pelvic inflammatory disease, NOS Genitourinary Female 1.01 0.909 1.13 0.798 352 3520 FALSE 0.0979971086492705 0.0143 0.0559 0.0316 0.157 0.84 1.03 0.757 1.41 -0.0116 0.158 0.942 0.988 0.723 1.35 0.0202 0.158 0.898 1.02 0.748 1.39 ukb-melanoma-gwas-catalog all 614.51 Cervicitis and endocervicitis Genitourinary Female 1.04 0.985 1.1 0.147 1317 13170 FALSE 0.832682665251824 0.042 0.029 0.11 0.0826 0.184 1.12 0.949 1.31 0.0106 0.0845 0.9 1.01 0.856 1.19 0.156 0.0819 0.0565 1.17 0.996 1.37 ukb-melanoma-gwas-catalog all 614.52 Vaginitis and vulvovaginitis Genitourinary Female 0.951 0.861 1.05 0.324 426 4260 FALSE 0.489454989793388 -0.0501 0.0509 0.352 0.14 0.0116 1.42 1.08 1.87 0.0346 0.149 0.816 1.04 0.772 1.39 -0.00728 0.151 0.961 0.993 0.738 1.34 ukb-melanoma-gwas-catalog all 614.53 Cyst or abscess of Bartholin's gland Genitourinary Female 1.01 0.937 1.09 0.787 754 7540 FALSE 0.104025267640935 0.0104 0.0384 -0.155 0.11 0.16 0.856 0.689 1.06 0.0811 0.105 0.44 1.08 0.883 1.33 -0.0677 0.109 0.534 0.934 0.754 1.16 ukb-melanoma-gwas-catalog all 614.54 Abscess or ulceration of vulva Genitourinary Female 0.919 0.812 1.04 0.184 274 2740 FALSE 0.735182176990464 -0.0841 0.0633 -0.00612 0.171 0.971 0.994 0.71 1.39 -0.203 0.179 0.257 0.816 0.572 1.16 -0.184 0.179 0.304 0.832 0.584 1.18 ukb-melanoma-gwas-catalog all 615 Endometriosis Genitourinary Female 1.05 1.01 1.08 0.00577 4035 40341 TRUE 2.23882418684427 0.0457 0.0166 0.0224 0.0475 0.637 1.02 0.932 1.12 0.0352 0.0474 0.458 1.04 0.944 1.14 0.109 0.0468 0.0193 1.12 1.02 1.22 ukb-melanoma-gwas-catalog all 617 Disorders secondary to childbirth, surgery, trauma Genitourinary Female 1.07 0.954 1.21 0.238 305 3050 FALSE 0.623423042943488 0.0706 0.0598 -0.0511 0.178 0.774 0.95 0.668 1.35 0.147 0.171 0.388 1.16 0.829 1.62 0.215 0.168 0.201 1.24 0.892 1.73 ukb-melanoma-gwas-catalog all 618 Genital prolapse Genitourinary Female 1.01 0.994 1.03 0.176 11829 118039 FALSE 0.75448733218585 0.0131 0.00967 0.0314 0.0276 0.255 1.03 0.978 1.09 0.0652 0.0274 0.0172 1.07 1.01 1.13 0.0464 0.0276 0.0926 1.05 0.992 1.11 ukb-melanoma-gwas-catalog all 618.1 Prolapse of vaginal walls Genitourinary Female 1.03 1.01 1.06 0.00847 7403 74030 TRUE 2.07211658966929 0.0322 0.0122 0.0597 0.0351 0.0895 1.06 0.991 1.14 0.108 0.0348 0.0019 1.11 1.04 1.19 0.107 0.0349 0.0021 1.11 1.04 1.19 ukb-melanoma-gwas-catalog all 618.2 Uterine/Uterovaginal prolapse Genitourinary Female 0.989 0.961 1.02 0.425 5397 53970 FALSE 0.371611069949688 -0.0114 0.0143 -0.00277 0.0404 0.945 0.997 0.921 1.08 0.0416 0.0401 0.299 1.04 0.964 1.13 -0.0477 0.0409 0.244 0.953 0.88 1.03 ukb-melanoma-gwas-catalog all 618.5 Prolapse of vaginal vault after hysterectomy Genitourinary Female 0.947 0.864 1.04 0.243 513 5130 FALSE 0.614393726401688 -0.0543 0.0465 0.21 0.127 0.0987 1.23 0.962 1.58 -0.00687 0.133 0.959 0.993 0.765 1.29 -0.0858 0.136 0.529 0.918 0.702 1.2 ukb-melanoma-gwas-catalog all 618.6 Vaginal enterocele, congenital or acquired Genitourinary Female 1 0.924 1.08 0.986 680 6800 FALSE 0.00612308505878879 0.000684 0.0403 0.112 0.114 0.329 1.12 0.893 1.4 0.0582 0.116 0.617 1.06 0.843 1.33 0.107 0.115 0.352 1.11 0.888 1.4 ukb-melanoma-gwas-catalog all 619 Noninflammatory female genital disorders Genitourinary Female 0.999 0.978 1.02 0.962 9258 92573 FALSE 0.0168249279621871 -0.000519 0.0109 -0.0215 0.0309 0.486 0.979 0.921 1.04 -0.014 0.0309 0.651 0.986 0.928 1.05 0.00182 0.0308 0.953 1 0.943 1.06 ukb-melanoma-gwas-catalog all 619.1 Noninflammatory disorders of ovary, fallopian tube, and broad ligament Genitourinary Female 0.942 0.872 1.02 0.127 722 7220 FALSE 0.896196279044043 -0.0598 0.0392 -0.0425 0.106 0.687 0.958 0.779 1.18 -0.24 0.111 0.0305 0.787 0.632 0.977 -0.21 0.11 0.056 0.81 0.652 1.01 ukb-melanoma-gwas-catalog all 619.2 Disorders of uterus, NEC Genitourinary Female 1.02 0.988 1.06 0.202 3312 33120 FALSE 0.694648630553376 0.0233 0.0183 -0.0575 0.052 0.268 0.944 0.853 1.05 -0.0117 0.0515 0.82 0.988 0.893 1.09 0.0178 0.0513 0.729 1.02 0.921 1.13 ukb-melanoma-gwas-catalog all 619.3 Noninflammatory disorders of cervix Genitourinary Female 1.01 0.975 1.05 0.497 2852 28513 FALSE 0.303643611266668 0.0134 0.0197 -0.0643 0.0561 0.252 0.938 0.84 1.05 -0.006 0.0555 0.914 0.994 0.892 1.11 0.021 0.0553 0.705 1.02 0.916 1.14 ukb-melanoma-gwas-catalog all 619.4 Noninflammatory disorders of vagina Genitourinary Female 0.963 0.917 1.01 0.137 1764 17640 FALSE 0.863279432843593 -0.0373 0.0251 0.0348 0.0695 0.617 1.04 0.904 1.19 -0.0699 0.0712 0.326 0.932 0.811 1.07 -0.0457 0.0708 0.518 0.955 0.831 1.1 ukb-melanoma-gwas-catalog all 619.5 Noninflammatory disorders of vulva and perineum Genitourinary Female 1.02 0.96 1.07 0.6 1342 13420 FALSE 0.221848749616356 0.0151 0.0287 0.0216 0.083 0.794 1.02 0.868 1.2 0.139 0.0809 0.0858 1.15 0.981 1.35 0.0861 0.0822 0.295 1.09 0.928 1.28 ukb-melanoma-gwas-catalog all 620 Dysplasia of female genital organs Genitourinary Female 0.976 0.766 1.24 0.844 72 720 FALSE 0.073657553374345 -0.024 0.122 0.0156 0.341 0.964 1.02 0.513 2.01 0.0852 0.339 0.802 1.09 0.553 2.15 -0.084 0.344 0.807 0.919 0.46 1.83 ukb-melanoma-gwas-catalog all 621 Endometrial hyperplasia Genitourinary Female 1.02 0.961 1.09 0.49 1132 11320 FALSE 0.309803919971486 0.0216 0.0313 0.00383 0.0893 0.966 1 0.842 1.2 0.0917 0.0877 0.296 1.1 0.923 1.3 0.0294 0.0892 0.741 1.03 0.865 1.23 ukb-melanoma-gwas-catalog all 622 Polyp of female genital organs Genitourinary Female 1.01 0.994 1.03 0.168 10804 108040 FALSE 0.774690718274137 0.014 0.0101 -0.0257 0.0287 0.37 0.975 0.921 1.03 -0.0151 0.0286 0.599 0.985 0.931 1.04 0.0128 0.0285 0.654 1.01 0.958 1.07 ukb-melanoma-gwas-catalog all 622.1 Polyp of corpus uteri Genitourinary Female 1.01 0.986 1.03 0.446 7854 78540 FALSE 0.350665141287858 0.00904 0.0119 -0.012 0.0335 0.72 0.988 0.925 1.06 -0.031 0.0337 0.358 0.969 0.908 1.04 0.0167 0.0334 0.617 1.02 0.952 1.09 ukb-melanoma-gwas-catalog all 622.2 Mucous polyp of cervix Genitourinary Female 1.03 0.994 1.07 0.106 3422 34220 FALSE 0.97469413473523 0.0291 0.018 -0.0333 0.0513 0.516 0.967 0.875 1.07 -0.000436 0.051 0.993 1 0.904 1.1 0.0458 0.0505 0.364 1.05 0.948 1.16 ukb-melanoma-gwas-catalog all 623 Hypertrophy of female genital organs Genitourinary Female 1.05 0.992 1.11 0.0891 1270 12700 FALSE 1.05012229596313 0.0501 0.0295 -0.073 0.0858 0.395 0.93 0.785 1.1 0.0938 0.0828 0.257 1.1 0.934 1.29 0.0929 0.0832 0.264 1.1 0.932 1.29 ukb-melanoma-gwas-catalog all 624 Symptoms involving female genital tract Genitourinary Female 1.03 0.955 1.1 0.471 810 8095 FALSE 0.326979092871104 0.0266 0.0369 -0.00856 0.108 0.937 0.991 0.802 1.23 0.165 0.104 0.113 1.18 0.962 1.45 0.127 0.105 0.225 1.14 0.925 1.4 ukb-melanoma-gwas-catalog all 624.1 Dystrophy of female genital tract Genitourinary Female 0.986 0.862 1.13 0.835 237 2370 FALSE 0.0783135245163979 -0.0141 0.0679 0.147 0.196 0.452 1.16 0.788 1.71 0.173 0.195 0.375 1.19 0.81 1.75 0.164 0.195 0.4 1.18 0.803 1.74 ukb-melanoma-gwas-catalog all 624.2 Atrophy of female genital tract Genitourinary Female 1.05 0.949 1.15 0.362 441 4410 FALSE 0.441291429466834 0.0455 0.0499 -0.0869 0.147 0.553 0.917 0.686 1.22 0.176 0.138 0.204 1.19 0.909 1.57 0.0845 0.141 0.55 1.09 0.824 1.44 ukb-melanoma-gwas-catalog all 625 Pain and other symptoms associated with female genital organs Genitourinary Female 1.02 0.987 1.06 0.207 2996 29960 FALSE 0.684029654543082 0.0243 0.0192 0.0326 0.0543 0.548 1.03 0.929 1.15 -0.0239 0.055 0.664 0.976 0.876 1.09 0.0595 0.0542 0.272 1.06 0.954 1.18 ukb-melanoma-gwas-catalog all 625.1 Dyspareunia Genitourinary Female 1.03 0.967 1.09 0.389 1188 11880 FALSE 0.410050398674292 0.0263 0.0305 -0.0477 0.0878 0.587 0.953 0.802 1.13 0.0863 0.0852 0.312 1.09 0.922 1.29 0.0341 0.0866 0.693 1.03 0.873 1.23 ukb-melanoma-gwas-catalog all 626 Disorders of menstruation and other abnormal bleeding from female genital tract Genitourinary Female 1.02 1 1.03 0.0446 18324 129160 TRUE 1.35066514128786 0.016 0.00797 0.0158 0.0227 0.487 1.02 0.972 1.06 0.0374 0.0227 0.0986 1.04 0.993 1.09 0.042 0.0226 0.0633 1.04 0.998 1.09 ukb-melanoma-gwas-catalog all 626.1 Irregular menstrual cycle/bleeding Genitourinary Female 1.01 0.995 1.03 0.182 15686 122281 FALSE 0.739928612014925 0.0114 0.00854 0.0172 0.0243 0.478 1.02 0.97 1.07 0.0232 0.0243 0.339 1.02 0.976 1.07 0.0394 0.0242 0.103 1.04 0.992 1.09 ukb-melanoma-gwas-catalog all 626.2 Dysmenorrhea Genitourinary Female 1.01 0.958 1.06 0.805 1781 17801 FALSE 0.0942041196321315 0.00615 0.0249 0.0472 0.0702 0.501 1.05 0.914 1.2 -0.0107 0.0711 0.881 0.989 0.86 1.14 0.0317 0.0707 0.653 1.03 0.899 1.19 ukb-melanoma-gwas-catalog all 626.4 Premenstrual tension syndromes Genitourinary Female 0.963 0.817 1.13 0.649 159 1588 FALSE 0.187755303199631 -0.0378 0.083 0.415 0.236 0.0791 1.51 0.953 2.43 0.372 0.239 0.119 1.45 0.909 2.34 0.0151 0.256 0.953 1.02 0.61 1.69 ukb-melanoma-gwas-catalog all 626.8 Infertility, female Genitourinary Female 1.11 1.05 1.17 0.000355 1366 13624 TRUE 3.44977164694491 0.101 0.0284 0.191 0.0837 0.0228 1.21 1.03 1.43 0.272 0.0824 0.000964 1.31 1.12 1.54 0.25 0.0832 0.00269 1.28 1.09 1.51 ukb-melanoma-gwas-catalog all 626.11 Absent or infrequent menstruation Genitourinary Female 0.961 0.809 1.14 0.644 144 1440 FALSE 0.191114132640188 -0.0401 0.087 -0.313 0.239 0.19 0.731 0.453 1.17 -0.338 0.244 0.166 0.713 0.438 1.15 -0.176 0.235 0.455 0.839 0.525 1.33 ukb-melanoma-gwas-catalog all 626.12 Excessive or frequent menstruation Genitourinary Female 1.01 0.991 1.03 0.28 9734 91841 FALSE 0.552841968657781 0.0115 0.0107 0.0297 0.0304 0.329 1.03 0.97 1.09 0.0446 0.0304 0.142 1.05 0.985 1.11 0.0438 0.0304 0.15 1.04 0.984 1.11 ukb-melanoma-gwas-catalog all 626.13 Irregular menstrual cycle Genitourinary Female 1.02 0.978 1.07 0.305 1985 19849 FALSE 0.515700160653214 0.0242 0.0236 0.0598 0.0671 0.373 1.06 0.931 1.21 0.0575 0.0672 0.392 1.06 0.928 1.21 0.0637 0.0672 0.344 1.07 0.934 1.22 ukb-melanoma-gwas-catalog all 626.14 Irregular menstrual bleeding Genitourinary Female 1.02 0.984 1.05 0.307 3809 38080 FALSE 0.512861624522813 0.0174 0.017 0.0356 0.0481 0.46 1.04 0.943 1.14 0.0078 0.0485 0.872 1.01 0.916 1.11 0.0206 0.0484 0.67 1.02 0.928 1.12 ukb-melanoma-gwas-catalog all 627 Menopausal and postmenopausal disorders Genitourinary Female 1 0.981 1.02 0.975 10631 106298 FALSE 0.0109953843014632 0.000319 0.0102 -0.0231 0.0289 0.424 0.977 0.923 1.03 -0.0164 0.0288 0.57 0.984 0.93 1.04 -0.000957 0.0288 0.973 0.999 0.944 1.06 ukb-melanoma-gwas-catalog all 627.1 Postmenopausal bleeding Genitourinary Female 1 0.98 1.02 0.858 9055 90540 FALSE 0.0665127121512946 0.00198 0.0111 -0.0313 0.0312 0.317 0.969 0.912 1.03 -0.024 0.0312 0.442 0.976 0.918 1.04 -0.00444 0.0311 0.887 0.996 0.937 1.06 ukb-melanoma-gwas-catalog all 627.2 Symptomatic menopause Genitourinary Female 0.92 0.789 1.07 0.28 184 1839 FALSE 0.552841968657781 -0.0835 0.0774 -0.243 0.223 0.275 0.784 0.502 1.22 0.0792 0.208 0.703 1.08 0.718 1.63 -0.131 0.217 0.546 0.877 0.571 1.35 ukb-melanoma-gwas-catalog all 627.3 Postmenopausal atrophic vaginitis Genitourinary Female 1.01 0.951 1.08 0.703 1114 11140 FALSE 0.153044674980176 0.012 0.0315 -0.0368 0.0894 0.681 0.964 0.809 1.15 0.0123 0.0885 0.89 1.01 0.851 1.2 -0.00847 0.089 0.924 0.992 0.833 1.18 ukb-melanoma-gwas-catalog all 627.4 Premenopausal menorrhagia Genitourinary Female 0.943 0.838 1.06 0.326 311 3110 FALSE 0.486782399932061 -0.0587 0.0597 0.12 0.16 0.455 1.13 0.823 1.55 -0.114 0.169 0.498 0.892 0.639 1.24 -0.21 0.172 0.222 0.811 0.576 1.14 ukb-melanoma-gwas-catalog all 628 Ovarian cyst Genitourinary Female 1.02 0.986 1.05 0.303 4755 47550 FALSE 0.518557371497695 0.0157 0.0153 0.0012 0.0434 0.978 1 0.92 1.09 0.0313 0.0431 0.467 1.03 0.948 1.12 0.0207 0.0433 0.633 1.02 0.938 1.11 ukb-melanoma-gwas-catalog all 634 Miscarriage; stillbirth Pregnancy Complications Female 1.02 0.987 1.04 0.301 5450 38533 FALSE 0.521433504406157 0.0151 0.0146 0.00568 0.0416 0.891 1.01 0.927 1.09 0.041 0.0413 0.321 1.04 0.961 1.13 0.0296 0.0415 0.476 1.03 0.95 1.12 ukb-melanoma-gwas-catalog all 634.1 Missed abortion/Hydatidiform mole Pregnancy Complications Female 1.06 0.999 1.12 0.0531 1251 12453 FALSE 1.27490547891853 0.0574 0.0297 -0.0261 0.0866 0.764 0.974 0.822 1.15 0.137 0.0836 0.101 1.15 0.974 1.35 0.112 0.0843 0.183 1.12 0.948 1.32 ukb-melanoma-gwas-catalog all 634.3 Ectopic pregnancy Pregnancy Complications Female 1.02 0.913 1.15 0.699 331 3307 FALSE 0.155522824254319 0.0223 0.0577 -0.144 0.168 0.391 0.866 0.621 1.2 0.0749 0.16 0.639 1.08 0.787 1.48 0.0471 0.162 0.771 1.05 0.762 1.44 ukb-melanoma-gwas-catalog all 635 Hemorrhage during pregnancy; childbirth and postpartum Pregnancy Complications Female 0.995 0.949 1.04 0.819 2003 17602 FALSE 0.0867160982395816 -0.00542 0.0237 -0.0491 0.0675 0.467 0.952 0.834 1.09 0.108 0.0653 0.0976 1.11 0.98 1.27 -0.0773 0.0682 0.257 0.926 0.81 1.06 ukb-melanoma-gwas-catalog all 635.2 Antepartum hemorrhage, abruptio placentae, and placenta previa Pregnancy Complications Female 0.978 0.912 1.05 0.537 866 8626 FALSE 0.270025714300444 -0.022 0.0357 -0.105 0.101 0.299 0.901 0.739 1.1 0.00593 0.0982 0.952 1.01 0.829 1.22 -0.125 0.102 0.217 0.882 0.722 1.08 ukb-melanoma-gwas-catalog all 635.3 Placenta previa and abruptio placenta Pregnancy Complications Female 1.02 0.961 1.08 0.545 1273 12329 FALSE 0.263603497723358 0.0179 0.0295 0.00858 0.0851 0.92 1.01 0.853 1.19 0.21 0.0817 0.0103 1.23 1.05 1.45 -0.0221 0.0862 0.798 0.978 0.826 1.16 ukb-melanoma-gwas-catalog all 636 Early or threatened labor; hemorrhage in early pregnancy Pregnancy Complications Female 1 0.96 1.04 0.982 2553 22013 FALSE 0.00788851221305034 0.00047 0.021 -0.0374 0.0593 0.528 0.963 0.858 1.08 -0.0143 0.0591 0.809 0.986 0.878 1.11 -0.0214 0.0593 0.719 0.979 0.871 1.1 ukb-melanoma-gwas-catalog all 636.2 Early onset of delivery Pregnancy Complications Female 0.988 0.909 1.07 0.777 617 6155 FALSE 0.109578981199086 -0.012 0.0423 -0.239 0.12 0.0466 0.787 0.621 0.996 -0.0732 0.116 0.527 0.929 0.74 1.17 -0.135 0.118 0.251 0.874 0.693 1.1 ukb-melanoma-gwas-catalog all 636.3 Hemorrhage in early pregnancy Pregnancy Complications Female 1.02 0.959 1.09 0.504 1082 10774 FALSE 0.297569463554475 0.0214 0.032 -0.0024 0.0915 0.979 0.998 0.834 1.19 0.0416 0.0907 0.646 1.04 0.873 1.25 0.0807 0.0903 0.371 1.08 0.908 1.29 ukb-melanoma-gwas-catalog all 638 Other high-risk pregnancy Pregnancy Complications Female 1.04 0.811 1.32 0.765 70 700 FALSE 0.116338564846382 0.0369 0.123 -0.536 0.4 0.181 0.585 0.253 1.29 0.315 0.328 0.337 1.37 0.718 2.66 0.156 0.345 0.651 1.17 0.589 2.34 ukb-melanoma-gwas-catalog all 642 Hypertension complicating pregnancy, childbirth, and the puerperium Pregnancy Complications Female 1.01 0.946 1.07 0.841 1112 11107 FALSE 0.0752040042020878 0.00633 0.0315 -0.0868 0.0884 0.326 0.917 0.771 1.09 -0.111 0.089 0.211 0.895 0.751 1.07 -0.0242 0.0875 0.782 0.976 0.822 1.16 ukb-melanoma-gwas-catalog all 642.1 Preeclampsia and eclampsia Pregnancy Complications Female 1.01 0.894 1.13 0.922 307 3063 FALSE 0.0352690789463706 0.0059 0.0599 -0.0332 0.166 0.841 0.967 0.698 1.34 -0.218 0.173 0.207 0.804 0.571 1.13 0.0106 0.164 0.948 1.01 0.731 1.4 ukb-melanoma-gwas-catalog all 643 Excessive vomiting in pregnancy Pregnancy Complications Female 1.13 0.987 1.29 0.0758 230 2299 FALSE 1.12033079436795 0.122 0.0686 0.058 0.2 0.772 1.06 0.714 1.58 0.00946 0.202 0.963 1.01 0.677 1.51 0.29 0.192 0.131 1.34 0.917 1.96 ukb-melanoma-gwas-catalog all 643.1 Hyperemesis gravidarum Pregnancy Complications Female 1.09 0.92 1.28 0.326 153 1529 FALSE 0.486782399932061 0.0826 0.0841 0.1 0.235 0.67 1.11 0.694 1.77 -0.101 0.246 0.682 0.904 0.553 1.47 0.119 0.236 0.614 1.13 0.706 1.8 ukb-melanoma-gwas-catalog all 645 Late pregnancy and failed induction Pregnancy Complications Female 1.03 0.968 1.09 0.38 1253 12474 FALSE 0.42021640338319 0.0261 0.0297 0.0714 0.084 0.395 1.07 0.911 1.27 0.0259 0.0849 0.76 1.03 0.869 1.21 0.0363 0.0846 0.668 1.04 0.878 1.22 ukb-melanoma-gwas-catalog all 646 Other complications of pregnancy NEC Pregnancy Complications Female 1 0.959 1.05 0.916 2230 20875 FALSE 0.0381045263321496 0.00237 0.0223 -0.0228 0.0632 0.718 0.977 0.863 1.11 -0.0534 0.0637 0.402 0.948 0.837 1.07 0.0376 0.0625 0.548 1.04 0.919 1.17 ukb-melanoma-gwas-catalog all 647 Infectious and parasitic complications affecting pregnancy Pregnancy Complications Female 0.909 0.706 1.17 0.448 68 680 FALSE 0.348721986001856 -0.0956 0.126 0.326 0.348 0.35 1.38 0.697 2.81 0.352 0.348 0.311 1.42 0.716 2.89 -0.478 0.411 0.244 0.62 0.26 1.4 ukb-melanoma-gwas-catalog all 649 Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium Pregnancy Complications Female 0.93 0.766 1.13 0.46 113 1130 FALSE 0.337242168318426 -0.0725 0.098 0.225 0.261 0.388 1.25 0.749 2.11 -0.21 0.287 0.465 0.811 0.455 1.43 -0.0745 0.279 0.79 0.928 0.531 1.62 ukb-melanoma-gwas-catalog all 650 Normal delivery Pregnancy Complications Female 0.96 0.916 1.01 0.0916 1925 19003 FALSE 1.03810452633215 -0.0405 0.024 -0.0838 0.0664 0.207 0.92 0.807 1.05 -0.167 0.0678 0.0139 0.846 0.741 0.967 -0.0974 0.0668 0.145 0.907 0.796 1.03 ukb-melanoma-gwas-catalog all 651 Multiple gestation Pregnancy Complications Female 1.11 0.992 1.24 0.069 346 3460 FALSE 1.16115090926274 0.103 0.0564 0.309 0.164 0.0595 1.36 0.988 1.89 0.167 0.169 0.322 1.18 0.848 1.65 0.325 0.164 0.0473 1.38 1 1.92 ukb-melanoma-gwas-catalog all 652 Malposition and malpresentation of fetus or obstruction Pregnancy Complications Female 1.02 0.975 1.08 0.335 1718 16535 FALSE 0.474955192963155 0.0245 0.0254 -0.003 0.0719 0.967 0.997 0.866 1.15 -0.00105 0.0719 0.988 0.999 0.867 1.15 0.0259 0.0717 0.718 1.03 0.892 1.18 ukb-melanoma-gwas-catalog all 653 Problems associated with amniotic cavity and membranes Pregnancy Complications Female 1.02 0.969 1.08 0.397 1401 13662 FALSE 0.401209493236885 0.0238 0.0281 -0.0663 0.0799 0.406 0.936 0.8 1.09 -0.0145 0.079 0.855 0.986 0.844 1.15 0.00847 0.0788 0.914 1.01 0.864 1.18 ukb-melanoma-gwas-catalog all 654 Other and unspecified complications of birth; puerperium affecting management of mother Pregnancy Complications Female 1.17 0.924 1.49 0.181 74 740 FALSE 0.742321425130815 0.16 0.12 -0.147 0.356 0.68 0.863 0.419 1.76 0.196 0.35 0.575 1.22 0.605 2.46 0.37 0.331 0.264 1.45 0.755 2.83 ukb-melanoma-gwas-catalog all 655 Known or suspected fetal abnormality affecting management of mother Pregnancy Complications Female 0.992 0.961 1.02 0.638 4309 29472 FALSE 0.195179321278838 -0.00778 0.0165 -0.0181 0.0465 0.698 0.982 0.896 1.08 -0.0322 0.0467 0.491 0.968 0.884 1.06 -0.00454 0.0465 0.922 0.995 0.909 1.09 ukb-melanoma-gwas-catalog all 656 Other perinatal conditions of fetus or newborn Pregnancy Complications Both 0.857 0.701 1.04 0.125 110 1090 FALSE 0.903089986991944 -0.155 0.101 0.514 0.265 0.0526 1.67 0.996 2.86 0.00667 0.29 0.982 1.01 0.565 1.8 -0.348 0.315 0.269 0.706 0.372 1.32 ukb-melanoma-gwas-catalog all 661 Fetal distress and abnormal forces of labor Pregnancy Complications Female 0.973 0.931 1.02 0.228 2267 18423 FALSE 0.642065152999546 -0.0271 0.0224 -0.0488 0.0621 0.432 0.952 0.843 1.08 -0.125 0.0634 0.0492 0.883 0.779 1 -0.0874 0.0628 0.164 0.916 0.81 1.04 ukb-melanoma-gwas-catalog all 663 Umbilical cord complications during labor and delivery Pregnancy Complications Female 0.98 0.896 1.07 0.66 533 5319 FALSE 0.180456064458131 -0.02 0.0455 -0.035 0.128 0.784 0.966 0.751 1.24 -0.0577 0.128 0.654 0.944 0.733 1.22 0.00972 0.127 0.939 1.01 0.787 1.3 ukb-melanoma-gwas-catalog all 665 Obstetrical/birth trauma Pregnancy Complications Female 0.976 0.948 1.01 0.114 5314 29494 FALSE 0.943095148663527 -0.0241 0.0152 -0.0111 0.0427 0.795 0.989 0.909 1.08 -0.0111 0.0428 0.795 0.989 0.909 1.08 -0.0642 0.0432 0.138 0.938 0.862 1.02 ukb-melanoma-gwas-catalog all 669 Complications of labor and delivery NEC Pregnancy Complications Female 1 0.96 1.04 0.975 2554 21200 FALSE 0.0109953843014632 0.000669 0.0211 0.0257 0.0591 0.664 1.03 0.914 1.15 -0.0235 0.0599 0.695 0.977 0.868 1.1 -0.00129 0.0597 0.983 0.999 0.888 1.12 ukb-melanoma-gwas-catalog all 671 Venous/cerebrovascular complications embolism in pregnancy and the puerperium Pregnancy Complications Female 1.11 0.948 1.31 0.189 164 1630 FALSE 0.723538195826756 0.107 0.0813 -0.266 0.235 0.258 0.766 0.479 1.22 -0.161 0.231 0.486 0.851 0.537 1.34 0.0904 0.218 0.678 1.09 0.713 1.68 ukb-melanoma-gwas-catalog all 674 Other complications of the puerperium NEC Pregnancy Complications Female 1.05 0.926 1.19 0.438 262 2609 FALSE 0.3585258894959 0.05 0.0646 -0.216 0.189 0.255 0.806 0.553 1.17 -0.00617 0.181 0.973 0.994 0.695 1.42 0.0765 0.178 0.667 1.08 0.761 1.53 ukb-melanoma-gwas-catalog all 676 Other disorders of the breast associated with childbirth and disorders of lactation Pregnancy Complications Female 1.09 0.842 1.41 0.5 63 624 FALSE 0.301029995663981 0.0878 0.13 -0.487 0.423 0.249 0.614 0.253 1.42 0.0216 0.374 0.954 1.02 0.481 2.17 0.388 0.346 0.262 1.47 0.748 2.98 ukb-melanoma-gwas-catalog all 679 Complications of in utero procedures Dermatologic Female 0.972 0.73 1.29 0.839 53 530 FALSE 0.0762380391712997 -0.0289 0.142 0.521 0.401 0.194 1.68 0.766 3.87 0.508 0.415 0.221 1.66 0.732 3.92 0.0466 0.435 0.915 1.05 0.432 2.56 ukb-melanoma-gwas-catalog all 681 Superficial cellulitis and abscess Dermatologic Both 1.04 1.01 1.06 0.00256 7421 74210 TRUE 2.59176003468815 0.0368 0.0122 0.0775 0.0348 0.0262 1.08 1.01 1.16 0.0753 0.0349 0.031 1.08 1.01 1.15 0.095 0.0349 0.00646 1.1 1.03 1.18 ukb-melanoma-gwas-catalog all 681.1 Cellulitis and abscess of fingers/toes Dermatologic Both 1.03 0.945 1.12 0.494 566 5660 FALSE 0.306273051076353 0.0302 0.0441 0.0133 0.124 0.915 1.01 0.793 1.29 0.0129 0.125 0.918 1.01 0.792 1.29 0.016 0.125 0.898 1.02 0.795 1.3 ukb-melanoma-gwas-catalog all 681.2 Cellulitis and abscess of face/neck Dermatologic Both 1.07 0.975 1.17 0.158 522 5220 FALSE 0.801342913045577 0.0651 0.0461 0.0355 0.136 0.794 1.04 0.793 1.35 0.184 0.132 0.164 1.2 0.927 1.56 0.248 0.131 0.0578 1.28 0.992 1.66 ukb-melanoma-gwas-catalog all 681.3 Cellulitis and abscess of arm/hand Dermatologic Both 1.04 1.01 1.07 0.0118 5514 55140 TRUE 1.92811799269387 0.0356 0.0142 0.0766 0.0403 0.0577 1.08 0.998 1.17 0.0601 0.0405 0.138 1.06 0.981 1.15 0.0911 0.0403 0.0239 1.1 1.01 1.19 ukb-melanoma-gwas-catalog all 681.5 Cellulitis and abscess of leg, except foot Dermatologic Both 1.04 1.01 1.06 0.0145 5521 55210 TRUE 1.83863199776503 0.0346 0.0141 0.0785 0.0403 0.0512 1.08 1 1.17 0.0557 0.0405 0.17 1.06 0.976 1.14 0.0892 0.0403 0.027 1.09 1.01 1.18 ukb-melanoma-gwas-catalog all 681.6 Cellulitis and abscess of foot, toe Dermatologic Both 1.04 1.01 1.07 0.0113 5477 54770 TRUE 1.94692155651658 0.036 0.0142 0.0747 0.0405 0.0649 1.08 0.995 1.17 0.062 0.0407 0.127 1.06 0.982 1.15 0.0918 0.0405 0.0233 1.1 1.01 1.19 ukb-melanoma-gwas-catalog all 681.7 Cellulitis and abscess of trunk Dermatologic Both 1.1 1.01 1.2 0.0254 600 6000 TRUE 1.59516628338006 0.0956 0.0428 0.212 0.125 0.0893 1.24 0.968 1.58 0.168 0.126 0.183 1.18 0.923 1.52 0.283 0.124 0.0221 1.33 1.04 1.7 ukb-melanoma-gwas-catalog all 686 Other local infections of skin and subcutaneous tissue Dermatologic Both 1.06 1 1.12 0.041 1348 13480 TRUE 1.38721614328026 0.0584 0.0286 0.21 0.0834 0.0118 1.23 1.05 1.45 0.265 0.0826 0.00134 1.3 1.11 1.53 0.185 0.084 0.0273 1.2 1.02 1.42 ukb-melanoma-gwas-catalog all 686.1 Carbuncle and furuncle Dermatologic Both 1.08 0.867 1.34 0.481 87 870 FALSE 0.317854923626168 0.0776 0.11 -0.141 0.327 0.666 0.869 0.448 1.66 0.0912 0.307 0.766 1.1 0.594 2.03 0.0308 0.308 0.92 1.03 0.557 1.91 ukb-melanoma-gwas-catalog all 687 Symptoms affecting skin Dermatologic Both 1.04 0.952 1.13 0.42 604 6040 FALSE 0.3767507096021 0.0345 0.0428 0.102 0.122 0.402 1.11 0.872 1.41 0.0721 0.122 0.555 1.07 0.845 1.37 0.0836 0.122 0.493 1.09 0.855 1.38 ukb-melanoma-gwas-catalog all 687.2 Localized superficial swelling, mass, or lump Dermatologic Both 1.04 0.921 1.18 0.521 284 2840 FALSE 0.283162276700476 0.04 0.0624 0.0388 0.178 0.828 1.04 0.731 1.48 0.0383 0.177 0.829 1.04 0.733 1.48 0.0935 0.176 0.595 1.1 0.776 1.56 ukb-melanoma-gwas-catalog all 687.3 Changes in skin texture Dermatologic Both 0.99 0.812 1.21 0.921 108 1080 FALSE 0.0357403698031511 -0.00992 0.0998 0.0983 0.281 0.726 1.1 0.631 1.94 0.0767 0.282 0.785 1.08 0.616 1.9 0.108 0.285 0.705 1.11 0.632 1.97 ukb-melanoma-gwas-catalog all 689 Disorder of skin and subcutaneous tissue NOS Dermatologic Both 1.11 1.08 1.14 1.61e-13 5765 57650 TRUE 12.7931741239682 0.102 0.0138 0.0616 0.0406 0.129 1.06 0.982 1.15 0.12 0.0401 0.00267 1.13 1.04 1.22 0.244 0.0392 5.45e-10 1.28 1.18 1.38 ukb-melanoma-gwas-catalog all 690 Erythematosquamous dermatosis Dermatologic Both 0.976 0.764 1.24 0.845 72 720 FALSE 0.0731432910503077 -0.0238 0.122 -0.222 0.369 0.546 0.801 0.374 1.68 0.42 0.322 0.192 1.52 0.809 2.93 0.0343 0.358 0.924 1.03 0.502 2.13 ukb-melanoma-gwas-catalog all 690.1 Seborrheic dermatitis Dermatologic Both 1.03 0.772 1.36 0.85 53 530 FALSE 0.0705810742857073 0.0268 0.141 -0.293 0.445 0.51 0.746 0.29 1.84 0.608 0.367 0.0975 1.84 0.898 3.92 -0.0468 0.436 0.914 0.954 0.39 2.3 ukb-melanoma-gwas-catalog all 691 Congenital anomalies of skin Dermatologic Both 1.15 0.955 1.4 0.137 120 1200 FALSE 0.863279432843593 0.143 0.0959 0.543 0.268 0.043 1.72 1.02 2.97 -0.0496 0.301 0.869 0.952 0.519 1.74 0.395 0.277 0.153 1.48 0.862 2.6 ukb-melanoma-gwas-catalog all 694 Dyschromia and Vitiligo Dermatologic Both 1.11 1.04 1.19 0.00133 987 9864 TRUE 2.87614835903291 0.107 0.0334 0.00715 0.0979 0.942 1.01 0.831 1.22 0.038 0.0968 0.694 1.04 0.859 1.26 0.248 0.0934 0.00796 1.28 1.07 1.54 ukb-melanoma-gwas-catalog all 694.1 Vitiligo Dermatologic Both 0.861 0.658 1.12 0.266 60 600 FALSE 0.575118363368933 -0.149 0.134 -0.734 0.403 0.0682 0.48 0.204 1.06 -0.372 0.365 0.308 0.69 0.326 1.42 -0.0489 0.342 0.886 0.952 0.479 1.89 ukb-melanoma-gwas-catalog all 694.2 Other dyschromia Dermatologic Both 1.16 1.08 1.25 8.27e-05 783 7830 TRUE 4.08249449044745 0.148 0.0375 0.124 0.111 0.263 1.13 0.911 1.41 0.0904 0.111 0.416 1.09 0.88 1.36 0.359 0.106 7e-04 1.43 1.16 1.77 ukb-melanoma-gwas-catalog all 694.3 Vascular disorders of skin Dermatologic Both 1 0.827 1.21 0.983 117 1164 FALSE 0.00744648216786438 0.00203 0.0969 -0.335 0.277 0.227 0.715 0.408 1.24 0.0473 0.253 0.852 1.05 0.634 1.74 -0.208 0.275 0.451 0.813 0.467 1.4 ukb-melanoma-gwas-catalog all 695 Erythematous conditions Dermatologic Both 1.02 0.978 1.06 0.367 2416 24160 FALSE 0.435333935747911 0.0193 0.0214 -0.0392 0.0611 0.521 0.962 0.853 1.08 0.00578 0.0604 0.924 1.01 0.893 1.13 0.0461 0.0601 0.443 1.05 0.931 1.18 ukb-melanoma-gwas-catalog all 695.1 Toxic erythema Dermatologic Both 0.981 0.804 1.2 0.845 109 1090 FALSE 0.0731432910503077 -0.0196 0.0999 -0.135 0.268 0.614 0.873 0.51 1.49 -0.771 0.321 0.0163 0.463 0.237 0.863 0.118 0.258 0.647 1.13 0.676 1.88 ukb-melanoma-gwas-catalog all 695.2 Bullous dermatoses Dermatologic Both 1.04 0.873 1.24 0.665 141 1410 FALSE 0.177178354696895 0.0383 0.0883 0.098 0.254 0.7 1.1 0.666 1.83 0.251 0.246 0.309 1.28 0.79 2.11 0.0668 0.256 0.794 1.07 0.643 1.78 ukb-melanoma-gwas-catalog all 695.3 Rosacea Dermatologic Both 1.08 0.957 1.21 0.217 310 3100 FALSE 0.66354026615147 0.0733 0.0593 0.0933 0.17 0.584 1.1 0.785 1.54 0.0363 0.173 0.833 1.04 0.738 1.46 0.185 0.167 0.269 1.2 0.866 1.68 ukb-melanoma-gwas-catalog all 695.4 Lupus (localized and systemic) Dermatologic Both 0.998 0.903 1.1 0.973 418 4180 FALSE 0.0118871597316481 -0.00172 0.0512 -0.0886 0.144 0.537 0.915 0.689 1.21 -0.182 0.146 0.215 0.834 0.624 1.11 0.0213 0.14 0.879 1.02 0.775 1.35 ukb-melanoma-gwas-catalog all 695.7 Prurigo and Lichen Dermatologic Both 1.01 0.938 1.09 0.8 777 7770 FALSE 0.0969100130080564 0.00956 0.0377 0.0333 0.106 0.754 1.03 0.839 1.27 0.0543 0.106 0.607 1.06 0.858 1.3 -0.0519 0.108 0.632 0.949 0.767 1.17 ukb-melanoma-gwas-catalog all 695.8 Other specified erythematous conditions Dermatologic Both 0.963 0.843 1.1 0.572 242 2420 FALSE 0.242603971206976 -0.038 0.0673 -0.0606 0.191 0.751 0.941 0.645 1.37 0.0176 0.187 0.925 1.02 0.704 1.47 -0.0432 0.189 0.819 0.958 0.658 1.39 ukb-melanoma-gwas-catalog all 695.9 Unspecified erythematous condition Dermatologic Both 1.07 0.97 1.17 0.182 468 4680 FALSE 0.739928612014925 0.0646 0.0484 -0.102 0.143 0.475 0.903 0.681 1.2 0.148 0.135 0.275 1.16 0.889 1.51 0.16 0.137 0.241 1.17 0.898 1.54 ukb-melanoma-gwas-catalog all 695.21 Dermatitis herpetiformis Dermatologic Both 0.941 0.714 1.24 0.661 57 570 FALSE 0.17979854051436 -0.0605 0.138 0.118 0.383 0.757 1.13 0.521 2.45 0.0547 0.379 0.885 1.06 0.493 2.27 -0.292 0.405 0.471 0.747 0.322 1.69 ukb-melanoma-gwas-catalog all 695.22 Pemphigus and pemphigoid Dermatologic Both 1.19 0.935 1.51 0.154 75 750 FALSE 0.812479279163537 0.171 0.12 0.175 0.369 0.635 1.19 0.567 2.55 0.556 0.348 0.111 1.74 0.88 3.59 0.504 0.351 0.151 1.66 0.828 3.43 ukb-melanoma-gwas-catalog all 695.41 Cutaneous lupus erythematosus Dermatologic Both 1.03 0.857 1.23 0.78 130 1300 FALSE 0.10790539730952 0.0255 0.0911 -0.26 0.263 0.323 0.771 0.455 1.3 -0.0903 0.253 0.721 0.914 0.551 1.51 0.0153 0.248 0.951 1.02 0.621 1.66 ukb-melanoma-gwas-catalog all 695.42 Systemic lupus erythematosus Dermatologic Both 0.984 0.881 1.1 0.78 342 3420 FALSE 0.10790539730952 -0.0158 0.0566 -0.0743 0.158 0.638 0.928 0.68 1.27 -0.207 0.163 0.204 0.813 0.589 1.12 0.0218 0.155 0.888 1.02 0.754 1.39 ukb-melanoma-gwas-catalog all 695.81 Erythema nodosum Dermatologic Both 0.963 0.762 1.22 0.751 76 760 FALSE 0.124360062995832 -0.0375 0.118 -0.508 0.346 0.142 0.602 0.295 1.19 -0.278 0.325 0.393 0.757 0.392 1.44 -0.0792 0.314 0.801 0.924 0.493 1.73 ukb-melanoma-gwas-catalog all 696 Psoriasis and related disorders Dermatologic Both 1.01 0.967 1.05 0.646 2290 22900 FALSE 0.189767482004916 0.0101 0.022 0.0553 0.0623 0.374 1.06 0.935 1.19 0.0542 0.0622 0.384 1.06 0.934 1.19 0.0138 0.0631 0.827 1.01 0.896 1.15 ukb-melanoma-gwas-catalog all 696.4 Psoriasis Dermatologic Both 1.01 0.964 1.05 0.735 2234 22340 FALSE 0.133712660915805 0.00754 0.0223 0.0662 0.0629 0.293 1.07 0.944 1.21 0.0537 0.063 0.395 1.06 0.932 1.19 0.00703 0.064 0.913 1.01 0.888 1.14 ukb-melanoma-gwas-catalog all 696.41 Psoriasis vulgaris Dermatologic Both 0.998 0.949 1.05 0.936 1681 16810 FALSE 0.0287241512618947 -0.00205 0.0257 0.0456 0.0718 0.525 1.05 0.909 1.21 -0.0058 0.0726 0.936 0.994 0.862 1.15 -0.0313 0.0734 0.67 0.969 0.839 1.12 ukb-melanoma-gwas-catalog all 696.42 Psoriatic arthropathy Dermatologic Both 1.03 0.953 1.11 0.456 708 7080 FALSE 0.341035157335565 0.0294 0.0395 0.107 0.114 0.347 1.11 0.89 1.39 0.228 0.111 0.0401 1.26 1.01 1.56 0.06 0.116 0.605 1.06 0.846 1.33 ukb-melanoma-gwas-catalog all 697 Sarcoidosis Dermatologic Both 0.976 0.893 1.07 0.585 549 5480 FALSE 0.23284413391782 -0.0245 0.0449 -0.215 0.128 0.0916 0.806 0.627 1.04 -0.0589 0.123 0.632 0.943 0.74 1.2 -0.125 0.125 0.316 0.882 0.69 1.13 ukb-melanoma-gwas-catalog all 698 Pruritus and related conditions Dermatologic Both 1.03 0.956 1.11 0.449 783 7830 FALSE 0.347753658996677 0.0284 0.0375 0.0719 0.107 0.5 1.07 0.872 1.33 0.0515 0.107 0.631 1.05 0.853 1.3 0.0758 0.107 0.479 1.08 0.874 1.33 ukb-melanoma-gwas-catalog all 700 Corns and callosities Dermatologic Both 1.05 0.934 1.19 0.39 293 2930 FALSE 0.408935392973501 0.0527 0.0613 -0.265 0.179 0.14 0.767 0.537 1.09 0.0912 0.165 0.58 1.1 0.792 1.52 -0.0497 0.172 0.772 0.952 0.677 1.34 ukb-melanoma-gwas-catalog all 701 Other hypertrophic and atrophic conditions of skin Dermatologic Both 1.09 1.05 1.12 4.29e-08 4782 47820 TRUE 7.36754270781528 0.0831 0.0152 0.0748 0.0444 0.0923 1.08 0.988 1.18 0.13 0.044 0.00319 1.14 1.04 1.24 0.231 0.0431 8.58e-08 1.26 1.16 1.37 ukb-melanoma-gwas-catalog all 701.1 Keratoderma, acquired Dermatologic Both 1.34 1.07 1.67 0.00919 86 860 TRUE 2.03668448861389 0.291 0.112 -0.15 0.344 0.663 0.861 0.427 1.72 0.101 0.328 0.759 1.11 0.573 2.15 0.596 0.303 0.0492 1.82 1 3.37 ukb-melanoma-gwas-catalog all 701.2 Scar conditions and fibrosis of skin Dermatologic Both 1.12 1.07 1.16 3.9e-07 2350 23500 TRUE 6.4089353929735 0.11 0.0216 0.108 0.0639 0.0912 1.11 0.983 1.26 0.164 0.0633 0.00957 1.18 1.04 1.33 0.302 0.0616 9.35e-07 1.35 1.2 1.53 ukb-melanoma-gwas-catalog all 701.3 Circumscribed scleroderma Dermatologic Both 1 0.764 1.31 0.997 59 590 FALSE 0.00130484168834428 0.000523 0.134 -0.222 0.409 0.587 0.801 0.344 1.83 0.398 0.366 0.277 1.49 0.722 3.16 0.118 0.385 0.76 1.12 0.517 2.47 ukb-melanoma-gwas-catalog all 701.4 Keloid scar Dermatologic Both 1.04 0.907 1.2 0.553 216 2160 FALSE 0.257274868695302 0.042 0.0709 -0.171 0.209 0.411 0.842 0.556 1.27 0.103 0.196 0.599 1.11 0.753 1.64 0.0462 0.197 0.815 1.05 0.709 1.55 ukb-melanoma-gwas-catalog all 701.5 Abnormal granulation tissue Dermatologic Both 0.994 0.903 1.1 0.908 454 4540 FALSE 0.0419141514789149 -0.00569 0.0492 0.0696 0.137 0.612 1.07 0.819 1.41 -0.0615 0.141 0.663 0.94 0.711 1.24 0.0362 0.139 0.794 1.04 0.789 1.36 ukb-melanoma-gwas-catalog all 701.6 Acquired acanthosis nigricans Dermatologic Both 1.16 0.942 1.42 0.161 102 1020 FALSE 0.79317412396815 0.145 0.103 0.218 0.319 0.494 1.24 0.658 2.38 0.413 0.308 0.181 1.51 0.822 2.84 0.589 0.302 0.0508 1.8 0.999 3.34 ukb-melanoma-gwas-catalog all 702 Degenerative skin conditions and other dermatoses Dermatologic Both 1.14 1.1 1.17 2.24e-19 5492 54920 TRUE 18.6497519816658 0.127 0.0142 0.0711 0.042 0.0907 1.07 0.989 1.17 0.161 0.0413 9.63e-05 1.17 1.08 1.27 0.302 0.0402 5.62e-14 1.35 1.25 1.46 ukb-melanoma-gwas-catalog all 702.1 Actinic keratosis Dermatologic Both 1.2 1.15 1.25 2.3e-18 2581 25810 TRUE 17.6382721639824 0.181 0.0207 0.0754 0.0626 0.229 1.08 0.954 1.22 0.19 0.0612 0.00189 1.21 1.07 1.36 0.436 0.0584 8.28e-14 1.55 1.38 1.74 ukb-melanoma-gwas-catalog all 702.2 Seborrheic keratosis Dermatologic Both 1.09 1.05 1.13 7.8e-06 3075 30750 TRUE 5.10790539730952 0.0846 0.0189 0.0638 0.0552 0.248 1.07 0.956 1.19 0.146 0.0543 0.00725 1.16 1.04 1.29 0.18 0.054 0.000875 1.2 1.08 1.33 ukb-melanoma-gwas-catalog all 703 Diseases of nail, NOS Dermatologic Both 1 0.899 1.12 0.956 355 3546 FALSE 0.0195421077238999 0.00309 0.0556 -0.0218 0.155 0.888 0.978 0.72 1.33 -0.0757 0.157 0.631 0.927 0.679 1.26 -0.0018 0.155 0.991 0.998 0.735 1.36 ukb-melanoma-gwas-catalog all 704 Diseases of hair and hair follicles Dermatologic Both 1.01 0.978 1.04 0.672 5287 52864 FALSE 0.172630726946175 0.00613 0.0145 0.0098 0.0409 0.81 1.01 0.932 1.09 -0.0359 0.0414 0.385 0.965 0.89 1.05 0.0496 0.0407 0.223 1.05 0.97 1.14 ukb-melanoma-gwas-catalog all 704.1 Alopecia Dermatologic Both 0.859 0.715 1.03 0.102 127 1270 FALSE 0.991399828238082 -0.151 0.0926 0.00313 0.244 0.99 1 0.618 1.63 -0.238 0.261 0.361 0.788 0.467 1.32 -0.273 0.262 0.298 0.761 0.45 1.28 ukb-melanoma-gwas-catalog all 704.8 Other specified diseases of hair and hair follicles Dermatologic Both 0.933 0.736 1.18 0.559 76 760 FALSE 0.252588192113577 -0.0695 0.119 0.00371 0.315 0.991 1 0.534 1.88 -0.266 0.332 0.423 0.767 0.391 1.48 -0.333 0.337 0.324 0.717 0.36 1.4 ukb-melanoma-gwas-catalog all 705 Disorders of sweat glands Dermatologic Both 1.08 0.939 1.23 0.283 229 2289 FALSE 0.54821356447571 0.0742 0.0692 0.119 0.206 0.563 1.13 0.749 1.7 0.436 0.195 0.0253 1.55 1.06 2.28 0.149 0.207 0.472 1.16 0.771 1.75 ukb-melanoma-gwas-catalog all 705.3 Hidradenitis Dermatologic Both 1.1 0.95 1.28 0.192 187 1869 FALSE 0.71669877129645 0.0997 0.0764 0.0167 0.229 0.942 1.02 0.645 1.6 0.372 0.214 0.082 1.45 0.954 2.23 0.126 0.224 0.575 1.13 0.728 1.77 ukb-melanoma-gwas-catalog all 706 Diseases of sebaceous glands Dermatologic Both 1.01 0.991 1.04 0.237 8876 88734 FALSE 0.625251653989896 0.0132 0.0112 0.0495 0.0315 0.117 1.05 0.988 1.12 -0.0205 0.0321 0.523 0.98 0.92 1.04 0.0728 0.0315 0.0209 1.08 1.01 1.14 ukb-melanoma-gwas-catalog all 706.1 Acne Dermatologic Both 0.914 0.723 1.15 0.441 78 780 FALSE 0.355561410532161 -0.0901 0.117 0.176 0.326 0.589 1.19 0.622 2.31 0.152 0.326 0.641 1.16 0.608 2.25 -0.0763 0.347 0.826 0.927 0.459 1.86 ukb-melanoma-gwas-catalog all 706.2 Sebaceous cyst Dermatologic Both 1.01 0.992 1.04 0.224 8804 88014 FALSE 0.649751981665837 0.0136 0.0112 0.0507 0.0317 0.109 1.05 0.989 1.12 -0.02 0.0322 0.535 0.98 0.92 1.04 0.0737 0.0317 0.0198 1.08 1.01 1.15 ukb-melanoma-gwas-catalog all 707 Chronic ulcer of skin Dermatologic Both 1.03 0.98 1.08 0.262 1990 19900 FALSE 0.581698708680255 0.0264 0.0236 0.0432 0.0671 0.52 1.04 0.915 1.19 0.0624 0.0669 0.351 1.06 0.934 1.21 0.0565 0.0672 0.401 1.06 0.927 1.21 ukb-melanoma-gwas-catalog all 707.1 Decubitus ulcer Dermatologic Both 1 0.937 1.07 0.935 913 9130 FALSE 0.0291883891274822 0.00284 0.0348 0.0088 0.0988 0.929 1.01 0.831 1.23 0.0898 0.0972 0.355 1.09 0.904 1.32 -0.0081 0.1 0.935 0.992 0.815 1.21 ukb-melanoma-gwas-catalog all 709 Diffuse diseases of connective tissue Dermatologic Both 0.983 0.949 1.02 0.346 3451 34510 FALSE 0.460923901207223 -0.0169 0.0179 0.00173 0.0503 0.973 1 0.908 1.11 -0.0137 0.0505 0.786 0.986 0.893 1.09 -0.0212 0.0507 0.677 0.979 0.886 1.08 ukb-melanoma-gwas-catalog all 709.2 Sicca syndrome Dermatologic Both 0.943 0.86 1.03 0.208 504 5040 FALSE 0.681936665037238 -0.059 0.0469 0.0167 0.13 0.898 1.02 0.787 1.31 -0.0393 0.132 0.765 0.961 0.742 1.25 -0.0741 0.133 0.577 0.929 0.715 1.21 ukb-melanoma-gwas-catalog all 709.3 Systemic sclerosis Dermatologic Both 0.963 0.824 1.13 0.637 174 1740 FALSE 0.19586056766465 -0.0373 0.0792 -0.242 0.219 0.269 0.785 0.507 1.21 -0.304 0.224 0.175 0.738 0.472 1.15 -0.102 0.212 0.631 0.903 0.592 1.37 ukb-melanoma-gwas-catalog all 709.6 Other specified diffuse diseases of connective tissue Dermatologic Both 1.07 0.83 1.38 0.589 65 650 FALSE 0.229884705212898 0.0686 0.127 -0.264 0.359 0.463 0.768 0.369 1.57 -0.0956 0.347 0.783 0.909 0.452 1.82 -0.0677 0.35 0.846 0.935 0.461 1.88 ukb-melanoma-gwas-catalog all 709.7 Unspecified diffuse connective tissue disease Dermatologic Both 0.991 0.952 1.03 0.65 2721 27210 FALSE 0.187086643357144 -0.00916 0.0202 0.0161 0.0568 0.776 1.02 0.909 1.14 0.00166 0.0571 0.977 1 0.896 1.12 0.00137 0.0572 0.981 1 0.895 1.12 ukb-melanoma-gwas-catalog all 710 Osteomyelitis, periostitis, and other infections involving bone Musculoskeletal Both 1.07 0.983 1.16 0.117 613 6130 FALSE 0.931814138253838 0.0664 0.0424 0.0337 0.123 0.783 1.03 0.813 1.32 0.0383 0.122 0.755 1.04 0.817 1.32 0.203 0.119 0.0869 1.23 0.971 1.55 ukb-melanoma-gwas-catalog all 710.1 Osteomyelitis Musculoskeletal Both 1.06 0.972 1.16 0.186 566 5660 FALSE 0.730487055782084 0.0584 0.0442 0.0496 0.126 0.694 1.05 0.82 1.35 0.00299 0.128 0.981 1 0.78 1.29 0.169 0.124 0.171 1.18 0.929 1.51 ukb-melanoma-gwas-catalog all 710.12 Chronic osteomyelitis Musculoskeletal Both 1.04 0.899 1.21 0.581 196 1960 FALSE 0.235823867609669 0.0414 0.0751 0.0732 0.214 0.733 1.08 0.704 1.65 0.136 0.213 0.523 1.15 0.752 1.75 0.155 0.213 0.466 1.17 0.767 1.79 ukb-melanoma-gwas-catalog all 710.19 Unspecified osteomyelitis Musculoskeletal Both 1.03 0.928 1.14 0.59 402 4020 FALSE 0.229147988357856 0.0282 0.0523 -0.00222 0.147 0.988 0.998 0.746 1.33 -0.113 0.151 0.454 0.893 0.662 1.2 0.105 0.144 0.468 1.11 0.836 1.48 ukb-melanoma-gwas-catalog all 711 Arthropathy associated with infections Musculoskeletal Both 0.975 0.883 1.08 0.616 429 4290 FALSE 0.210419287835575 -0.0254 0.0506 -0.0348 0.143 0.807 0.966 0.729 1.28 0.033 0.141 0.815 1.03 0.783 1.36 -0.0687 0.144 0.632 0.934 0.703 1.24 ukb-melanoma-gwas-catalog all 711.1 Pyogenic arthritis Musculoskeletal Both 0.989 0.883 1.11 0.852 330 3300 FALSE 0.0695604052332999 -0.0107 0.0576 0.015 0.163 0.927 1.02 0.736 1.4 0.0803 0.161 0.617 1.08 0.79 1.49 -0.0294 0.165 0.858 0.971 0.702 1.34 ukb-melanoma-gwas-catalog all 712 Infective connective tissue disorders Musculoskeletal Both 0.872 0.694 1.1 0.235 82 820 FALSE 0.628932137728264 -0.137 0.115 0.186 0.305 0.541 1.2 0.658 2.23 0.0353 0.313 0.91 1.04 0.555 1.94 -0.402 0.349 0.249 0.669 0.326 1.34 ukb-melanoma-gwas-catalog all 713 Arthropathy associated with other disorders classified elsewhere Musculoskeletal Both 1.09 0.921 1.29 0.31 151 1510 FALSE 0.508638306165727 0.0862 0.085 0.111 0.242 0.648 1.12 0.691 1.81 0.0847 0.243 0.728 1.09 0.672 1.77 0.128 0.242 0.598 1.14 0.704 1.84 ukb-melanoma-gwas-catalog all 713.5 Arthropathy associated with neurological disorders Musculoskeletal Both 1.05 0.818 1.35 0.689 68 680 FALSE 0.161780778092374 0.0505 0.126 0.00674 0.357 0.985 1.01 0.49 2.06 -0.25 0.372 0.501 0.779 0.363 1.64 0.152 0.338 0.652 1.16 0.595 2.31 ukb-melanoma-gwas-catalog all 714 Rheumatoid arthritis and other inflammatory polyarthropathies Musculoskeletal Both 1.01 0.979 1.04 0.576 4858 48575 FALSE 0.239577516576788 0.00844 0.0151 0.0254 0.0425 0.551 1.03 0.944 1.11 0.00338 0.0428 0.937 1 0.923 1.09 0.00352 0.0429 0.935 1 0.923 1.09 ukb-melanoma-gwas-catalog all 714.1 Rheumatoid arthritis Musculoskeletal Both 1.02 0.987 1.05 0.244 4394 43935 FALSE 0.612610173661271 0.0185 0.0159 0.0488 0.0449 0.277 1.05 0.962 1.15 0.0254 0.0451 0.573 1.03 0.939 1.12 0.0269 0.0452 0.552 1.03 0.94 1.12 ukb-melanoma-gwas-catalog all 715 Other inflammatory spondylopathies Musculoskeletal Both 1 0.953 1.05 0.923 1670 16700 FALSE 0.0347982989740879 0.00247 0.0257 -0.091 0.0724 0.209 0.913 0.792 1.05 -0.0948 0.0725 0.191 0.91 0.789 1.05 -0.0164 0.0714 0.819 0.984 0.855 1.13 ukb-melanoma-gwas-catalog all 715.1 Sacroiliitis NEC Musculoskeletal Both 0.865 0.711 1.05 0.139 113 1130 FALSE 0.856985199745905 -0.145 0.0983 -0.092 0.257 0.721 0.912 0.546 1.52 -0.358 0.277 0.195 0.699 0.399 1.2 -0.349 0.272 0.2 0.706 0.408 1.21 ukb-melanoma-gwas-catalog all 715.2 Ankylosing spondylitis Musculoskeletal Both 1 0.922 1.09 0.967 619 6190 FALSE 0.0145735259169983 0.00173 0.0422 0.152 0.117 0.193 1.16 0.925 1.47 -0.0638 0.123 0.604 0.938 0.736 1.19 0.0786 0.12 0.512 1.08 0.855 1.37 ukb-melanoma-gwas-catalog all 716 Other arthropathies Musculoskeletal Both 1.01 1 1.02 0.0445 37608 265965 TRUE 1.35163998901907 0.0112 0.00556 0.0333 0.0158 0.035 1.03 1 1.07 0.0524 0.0157 0.000851 1.05 1.02 1.09 0.0312 0.0158 0.0487 1.03 1 1.06 ukb-melanoma-gwas-catalog all 716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal Both 1 0.97 1.04 0.819 3517 35170 FALSE 0.0867160982395816 0.00407 0.0178 0.0489 0.0498 0.326 1.05 0.952 1.16 -0.00146 0.0504 0.977 0.999 0.905 1.1 -0.00388 0.0506 0.939 0.996 0.902 1.1 ukb-melanoma-gwas-catalog all 716.2 Unspecified monoarthritis Musculoskeletal Both 1.02 1 1.03 0.0439 15561 155610 TRUE 1.35753547975788 0.017 0.00843 0.0395 0.024 0.1 1.04 0.992 1.09 0.0568 0.024 0.0178 1.06 1.01 1.11 0.0573 0.024 0.017 1.06 1.01 1.11 ukb-melanoma-gwas-catalog all 716.9 Arthropathy NOS Musculoskeletal Both 1.01 1 1.02 0.0183 35982 254727 TRUE 1.73754891026957 0.0134 0.00568 0.0304 0.0162 0.0601 1.03 0.999 1.06 0.0584 0.0161 0.000281 1.06 1.03 1.09 0.036 0.0162 0.0261 1.04 1 1.07 ukb-melanoma-gwas-catalog all 717 Polymyalgia Rheumatica Musculoskeletal Both 0.987 0.929 1.05 0.684 1152 11520 FALSE 0.164943898279884 -0.0126 0.0309 0.168 0.0869 0.0529 1.18 0.998 1.4 0.0382 0.0894 0.669 1.04 0.872 1.24 0.0702 0.0889 0.43 1.07 0.901 1.28 ukb-melanoma-gwas-catalog all 720 Spinal stenosis Musculoskeletal Both 1 0.971 1.04 0.791 3715 37150 FALSE 0.101823516502323 0.00457 0.0172 0.0368 0.0487 0.449 1.04 0.943 1.14 0.0119 0.049 0.808 1.01 0.919 1.11 0.0301 0.049 0.539 1.03 0.936 1.13 ukb-melanoma-gwas-catalog all 721 Spondylosis and allied disorders Musculoskeletal Both 1.01 0.992 1.04 0.212 7872 78720 FALSE 0.673664139071249 0.0148 0.0119 0.000894 0.0336 0.979 1 0.937 1.07 0.0153 0.0336 0.649 1.02 0.951 1.08 0.0331 0.0335 0.323 1.03 0.968 1.1 ukb-melanoma-gwas-catalog all 721.1 Spondylosis without myelopathy Musculoskeletal Both 1.01 0.976 1.03 0.733 5042 50420 FALSE 0.134896025358872 0.00506 0.0148 -0.0418 0.0418 0.318 0.959 0.884 1.04 -0.0537 0.042 0.201 0.948 0.873 1.03 0.00983 0.0415 0.813 1.01 0.931 1.1 ukb-melanoma-gwas-catalog all 721.2 Spondylosis with myelopathy Musculoskeletal Both 1.19 1.02 1.38 0.0218 189 1890 TRUE 1.6615435063954 0.173 0.0752 0.0314 0.225 0.889 1.03 0.66 1.62 0.182 0.219 0.405 1.2 0.779 1.86 0.311 0.213 0.144 1.36 0.899 2.09 ukb-melanoma-gwas-catalog all 721.8 Other allied disorders of spine Musculoskeletal Both 1.09 0.979 1.22 0.113 351 3510 FALSE 0.94692155651658 0.0887 0.056 0.128 0.166 0.439 1.14 0.82 1.58 0.249 0.162 0.124 1.28 0.934 1.77 0.327 0.161 0.042 1.39 1.01 1.91 ukb-melanoma-gwas-catalog all 722 Intervertebral disc disorders Musculoskeletal Both 0.994 0.973 1.02 0.574 9170 91700 FALSE 0.241088107602026 -0.00618 0.011 -0.0156 0.0309 0.613 0.984 0.927 1.05 -0.0233 0.031 0.452 0.977 0.919 1.04 -0.0371 0.0311 0.233 0.964 0.907 1.02 ukb-melanoma-gwas-catalog all 722.1 Displacement of intervertebral disc Musculoskeletal Both 0.961 0.877 1.05 0.399 508 5080 FALSE 0.399027104313252 -0.0395 0.0468 0.0354 0.129 0.784 1.04 0.803 1.34 -0.0997 0.133 0.454 0.905 0.696 1.18 -0.0485 0.132 0.713 0.953 0.735 1.23 ukb-melanoma-gwas-catalog all 722.6 Degeneration of intervertebral disc Musculoskeletal Both 1.03 0.986 1.07 0.21 2826 28260 FALSE 0.677780705266081 0.0248 0.0198 -0.0137 0.0564 0.808 0.986 0.883 1.1 0.0194 0.056 0.729 1.02 0.914 1.14 0.0583 0.0557 0.295 1.06 0.95 1.18 ukb-melanoma-gwas-catalog all 722.8 Postlaminectomy syndrome Musculoskeletal Both 1.24 0.964 1.61 0.0901 67 670 FALSE 1.04527520902094 0.217 0.128 0.199 0.36 0.58 1.22 0.593 2.54 -0.273 0.393 0.487 0.761 0.337 1.68 0.512 0.349 0.143 1.67 0.84 3.41 ukb-melanoma-gwas-catalog all 722.9 Other and unspecified disc disorder Musculoskeletal Both 0.979 0.949 1.01 0.182 4398 43980 FALSE 0.739928612014925 -0.0212 0.0159 -0.0845 0.0444 0.0572 0.919 0.842 1 -0.068 0.0443 0.125 0.934 0.856 1.02 -0.0907 0.0447 0.0422 0.913 0.837 0.997 ukb-melanoma-gwas-catalog all 723 Other disorders of cervical region Musculoskeletal Both 0.946 0.864 1.04 0.23 521 5210 FALSE 0.638272163982407 -0.0554 0.0461 -0.19 0.128 0.139 0.827 0.642 1.06 -0.0777 0.126 0.536 0.925 0.722 1.18 -0.202 0.129 0.118 0.817 0.633 1.05 ukb-melanoma-gwas-catalog all 723.1 Torticollis Musculoskeletal Both 1.05 0.861 1.28 0.619 107 1070 FALSE 0.208309350979882 0.0498 0.1 0.0207 0.296 0.944 1.02 0.564 1.85 0.271 0.278 0.329 1.31 0.759 2.3 0.0574 0.289 0.843 1.06 0.595 1.89 ukb-melanoma-gwas-catalog all 724 Other and unspecified disorders of back Musculoskeletal Both 0.992 0.948 1.04 0.736 2076 20760 FALSE 0.133122185662501 -0.00778 0.0231 -0.0727 0.0655 0.267 0.93 0.818 1.06 0.031 0.064 0.628 1.03 0.91 1.17 -0.0525 0.0654 0.422 0.949 0.835 1.08 ukb-melanoma-gwas-catalog all 724.1 Disorders of sacrum Musculoskeletal Both 0.993 0.896 1.1 0.893 404 4040 FALSE 0.0491485411114536 -0.00703 0.0521 0.197 0.147 0.178 1.22 0.913 1.63 0.132 0.149 0.375 1.14 0.851 1.53 0.0406 0.152 0.789 1.04 0.772 1.41 ukb-melanoma-gwas-catalog all 724.2 Disorders of coccyx Musculoskeletal Both 0.983 0.887 1.09 0.738 407 4070 FALSE 0.131943638176958 -0.0174 0.052 0.185 0.146 0.205 1.2 0.903 1.61 0.138 0.148 0.353 1.15 0.858 1.54 0.029 0.151 0.848 1.03 0.764 1.39 ukb-melanoma-gwas-catalog all 724.8 Other symptoms referable to back Musculoskeletal Both 0.892 0.689 1.16 0.379 63 630 FALSE 0.421360790031928 -0.114 0.13 0.119 0.34 0.726 1.13 0.572 2.23 -0.361 0.368 0.328 0.697 0.327 1.45 -0.314 0.366 0.392 0.731 0.344 1.51 ukb-melanoma-gwas-catalog all 724.9 Other unspecified back disorders Musculoskeletal Both 0.992 0.943 1.04 0.77 1616 16160 FALSE 0.113509274827518 -0.00764 0.0262 -0.157 0.0745 0.0349 0.855 0.738 0.989 -0.00906 0.072 0.9 0.991 0.86 1.14 -0.0831 0.0735 0.258 0.92 0.797 1.06 ukb-melanoma-gwas-catalog all 726 Peripheral enthesopathies and allied syndromes Musculoskeletal Both 1.01 0.997 1.03 0.119 14821 148210 FALSE 0.924453038607469 0.0135 0.00864 0.0124 0.0245 0.612 1.01 0.965 1.06 0.0241 0.0245 0.326 1.02 0.976 1.07 0.0321 0.0245 0.19 1.03 0.984 1.08 ukb-melanoma-gwas-catalog all 726.1 Enthesopathy Musculoskeletal Both 1.02 0.999 1.04 0.0561 9557 95570 FALSE 1.25103713874384 0.0205 0.0108 0.000342 0.0305 0.991 1 0.942 1.06 -0.0123 0.0306 0.689 0.988 0.93 1.05 0.0501 0.0303 0.098 1.05 0.991 1.12 ukb-melanoma-gwas-catalog all 726.2 Synoviopathy Musculoskeletal Both 0.962 0.858 1.08 0.498 330 3300 FALSE 0.302770657240282 -0.0393 0.0579 0.228 0.159 0.153 1.26 0.919 1.72 0.151 0.162 0.353 1.16 0.845 1.6 -0.14 0.174 0.422 0.869 0.615 1.23 ukb-melanoma-gwas-catalog all 726.3 Bursitis Musculoskeletal Both 1.05 0.98 1.13 0.163 856 8560 FALSE 0.787812395596042 0.05 0.0358 0.0696 0.103 0.5 1.07 0.875 1.31 0.123 0.102 0.23 1.13 0.925 1.38 0.107 0.103 0.298 1.11 0.91 1.36 ukb-melanoma-gwas-catalog all 727 Other disorders of synovium, tendon, and bursa Musculoskeletal Both 1.01 0.984 1.03 0.511 7593 75930 FALSE 0.291579099865287 0.00793 0.0121 0.00267 0.0342 0.938 1 0.938 1.07 -0.0109 0.0343 0.749 0.989 0.925 1.06 0.0289 0.0341 0.396 1.03 0.963 1.1 ukb-melanoma-gwas-catalog all 727.1 Synovitis and tenosynovitis Musculoskeletal Both 1.01 0.966 1.05 0.797 2738 27380 FALSE 0.0985416786038876 0.00516 0.0201 0.0156 0.057 0.785 1.02 0.908 1.14 0.0596 0.0565 0.291 1.06 0.95 1.19 -0.0027 0.0573 0.962 0.997 0.891 1.12 ukb-melanoma-gwas-catalog all 727.2 Bursitis disorders Musculoskeletal Both 1.02 0.83 1.24 0.882 106 1060 FALSE 0.0545314148681803 0.0151 0.101 -0.343 0.289 0.235 0.71 0.396 1.26 -0.286 0.283 0.313 0.751 0.424 1.31 -0.0606 0.268 0.822 0.941 0.551 1.6 ukb-melanoma-gwas-catalog all 727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal Both 0.997 0.962 1.03 0.889 3175 31750 FALSE 0.0510982390297863 -0.0026 0.0187 -0.0347 0.0522 0.507 0.966 0.872 1.07 -0.102 0.0531 0.0554 0.903 0.814 1 -0.0152 0.0522 0.771 0.985 0.889 1.09 ukb-melanoma-gwas-catalog all 727.5 Rupture of synovium Musculoskeletal Both 1.07 0.984 1.17 0.11 587 5870 FALSE 0.958607314841775 0.0691 0.0432 0.128 0.127 0.315 1.14 0.885 1.46 0.16 0.126 0.205 1.17 0.916 1.51 0.29 0.123 0.0186 1.34 1.05 1.7 ukb-melanoma-gwas-catalog all 727.6 Rupture of tendon, nontraumatic Musculoskeletal Both 1.01 0.906 1.13 0.847 352 3520 FALSE 0.0721165896692931 0.0108 0.0559 0.118 0.156 0.448 1.13 0.828 1.53 -0.182 0.168 0.276 0.833 0.598 1.16 0.185 0.155 0.232 1.2 0.888 1.63 ukb-melanoma-gwas-catalog all 727.7 Contracture of tendon (sheath) Musculoskeletal Both 1.03 0.862 1.22 0.774 142 1420 FALSE 0.111259039317107 0.0252 0.0878 -0.00669 0.252 0.979 0.993 0.6 1.64 0.0444 0.246 0.857 1.05 0.641 1.71 0.079 0.245 0.747 1.08 0.666 1.76 ukb-melanoma-gwas-catalog all 728 Disorders of muscle, ligament, and fascia Musculoskeletal Both 1.03 0.998 1.07 0.0613 3697 36970 FALSE 1.21253952548158 0.0324 0.0173 0.0238 0.0492 0.629 1.02 0.93 1.13 -0.000488 0.0495 0.992 1 0.907 1.1 0.089 0.0487 0.0673 1.09 0.994 1.2 ukb-melanoma-gwas-catalog all 728.7 Fasciitis Musculoskeletal Both 1.03 0.997 1.07 0.0717 3482 34820 FALSE 1.1444808443322 0.0321 0.0178 0.0387 0.0506 0.444 1.04 0.941 1.15 -0.0194 0.0513 0.705 0.981 0.887 1.08 0.0899 0.0501 0.0729 1.09 0.992 1.21 ukb-melanoma-gwas-catalog all 728.71 Contracture of palmar fascia [Dupuytren's disease] Musculoskeletal Both 1.03 0.997 1.07 0.0731 3482 34820 FALSE 1.13608262304214 0.0319 0.0178 0.0386 0.0506 0.446 1.04 0.941 1.15 -0.0193 0.0513 0.707 0.981 0.887 1.08 0.0899 0.0501 0.073 1.09 0.992 1.21 ukb-melanoma-gwas-catalog all 729 Other disorders of soft tissues Musculoskeletal Both 1.02 0.989 1.04 0.257 6051 60510 FALSE 0.590066876668705 0.0153 0.0135 0.0431 0.0383 0.26 1.04 0.969 1.13 0.029 0.0385 0.451 1.03 0.955 1.11 0.0474 0.0384 0.217 1.05 0.972 1.13 ukb-melanoma-gwas-catalog all 729.1 Rheumatism, unspecified and fibrositis Musculoskeletal Both 1.02 0.955 1.09 0.57 1004 10040 FALSE 0.244125144327509 0.0188 0.0331 -0.0476 0.0949 0.616 0.954 0.791 1.15 0.0402 0.0932 0.666 1.04 0.867 1.25 0.0436 0.0932 0.64 1.04 0.87 1.25 ukb-melanoma-gwas-catalog all 731 Osteitis deformans and osteopathies associated with other disorders classified elsewhere Musculoskeletal Both 1.07 0.95 1.22 0.252 277 2770 FALSE 0.598599459218456 0.0718 0.0627 0.105 0.176 0.55 1.11 0.785 1.57 -0.233 0.191 0.224 0.793 0.541 1.15 0.264 0.172 0.125 1.3 0.929 1.83 ukb-melanoma-gwas-catalog all 731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal Both 1.07 0.939 1.21 0.319 262 2620 FALSE 0.496209316942819 0.0643 0.0644 0.138 0.18 0.445 1.15 0.805 1.64 -0.233 0.197 0.237 0.792 0.535 1.17 0.244 0.178 0.17 1.28 0.9 1.82 ukb-melanoma-gwas-catalog all 732 Osteochondropathies Musculoskeletal Both 0.946 0.859 1.04 0.248 472 4720 FALSE 0.605548319173784 -0.056 0.0485 -0.228 0.136 0.0937 0.796 0.609 1.04 -0.058 0.131 0.657 0.944 0.73 1.22 -0.222 0.136 0.103 0.801 0.611 1.05 ukb-melanoma-gwas-catalog all 732.1 Juvenile osteochondrosis Musculoskeletal Both 0.994 0.861 1.15 0.937 207 2070 FALSE 0.0282604091122217 -0.00575 0.0728 -0.127 0.208 0.542 0.881 0.582 1.33 0.0849 0.197 0.667 1.09 0.738 1.61 -0.0951 0.207 0.646 0.909 0.602 1.37 ukb-melanoma-gwas-catalog all 732.7 Osteochondritis dissecans Musculoskeletal Both 0.869 0.657 1.14 0.307 59 590 FALSE 0.512861624522813 -0.141 0.138 -0.154 0.354 0.663 0.857 0.419 1.74 -0.156 0.362 0.667 0.856 0.411 1.76 -0.507 0.401 0.206 0.602 0.261 1.33 ukb-melanoma-gwas-catalog all 733 Other disorders of bone and cartilage Musculoskeletal Both 1.02 0.969 1.07 0.487 1792 17920 FALSE 0.312471038785366 0.0173 0.0248 -0.108 0.0715 0.132 0.898 0.78 1.03 0.0441 0.0689 0.522 1.05 0.913 1.2 0.000125 0.07 0.999 1 0.872 1.15 ukb-melanoma-gwas-catalog all 733.2 Cyst of bone Musculoskeletal Both 0.989 0.881 1.11 0.847 319 3190 FALSE 0.0721165896692931 -0.0114 0.0588 -0.0496 0.164 0.762 0.952 0.688 1.31 -0.0449 0.163 0.784 0.956 0.693 1.32 -0.106 0.167 0.525 0.899 0.646 1.25 ukb-melanoma-gwas-catalog all 735 Acquired foot deformities Musculoskeletal Both 1.02 0.996 1.04 0.124 9764 97640 FALSE 0.906578314837765 0.0164 0.0106 0.0334 0.0302 0.269 1.03 0.974 1.1 0.0315 0.0303 0.297 1.03 0.973 1.1 0.0473 0.0302 0.117 1.05 0.988 1.11 ukb-melanoma-gwas-catalog all 735.1 Flat foot Musculoskeletal Both 0.97 0.835 1.13 0.692 190 1900 FALSE 0.159893905543242 -0.0301 0.076 0.131 0.214 0.541 1.14 0.747 1.75 0.271 0.209 0.194 1.31 0.87 1.99 -0.126 0.229 0.582 0.882 0.558 1.39 ukb-melanoma-gwas-catalog all 735.2 Acquired toe deformities Musculoskeletal Both 1.03 0.997 1.06 0.0826 5091 50910 FALSE 1.08301995267962 0.0256 0.0147 0.0268 0.0418 0.523 1.03 0.946 1.11 0.0268 0.0419 0.522 1.03 0.946 1.12 0.0417 0.0418 0.319 1.04 0.96 1.13 ukb-melanoma-gwas-catalog all 735.3 Hallux valgus (Bunion) Musculoskeletal Both 1.02 0.992 1.04 0.179 6639 66390 FALSE 0.747146969020107 0.0173 0.0129 0.0291 0.0367 0.428 1.03 0.958 1.11 0.0315 0.0367 0.39 1.03 0.96 1.11 0.0604 0.0366 0.0991 1.06 0.989 1.14 ukb-melanoma-gwas-catalog all 735.21 Hammer toe (acquired) Musculoskeletal Both 1 0.955 1.05 0.951 1914 19140 FALSE 0.0218194830625861 0.00148 0.024 -0.00482 0.0679 0.943 0.995 0.871 1.14 0.00104 0.0678 0.988 1 0.876 1.14 -0.0103 0.068 0.88 0.99 0.866 1.13 ukb-melanoma-gwas-catalog all 735.23 Hallux rigidus Musculoskeletal Both 1.05 1 1.11 0.0506 1548 15480 FALSE 1.2958494831602 0.0522 0.0267 0.00425 0.0766 0.956 1 0.864 1.17 0.0887 0.0754 0.239 1.09 0.943 1.27 0.0737 0.076 0.332 1.08 0.927 1.25 ukb-melanoma-gwas-catalog all 736 Other acquired deformities of limbs Musculoskeletal Both 0.999 0.949 1.05 0.957 1644 16440 FALSE 0.0190880622231565 -0.00139 0.026 0.0614 0.0732 0.401 1.06 0.921 1.23 0.0257 0.0738 0.728 1.03 0.888 1.19 0.0155 0.0742 0.835 1.02 0.878 1.17 ukb-melanoma-gwas-catalog all 736.2 Acquired deformities of finger Musculoskeletal Both 1.04 0.914 1.19 0.533 248 2480 FALSE 0.273272790973428 0.0418 0.0669 0.0655 0.194 0.736 1.07 0.727 1.57 0.119 0.192 0.536 1.13 0.771 1.65 0.23 0.188 0.222 1.26 0.869 1.83 ukb-melanoma-gwas-catalog all 737 Curvature of spine Musculoskeletal Both 1.04 0.979 1.11 0.205 1135 11350 FALSE 0.688246138944246 0.0395 0.0312 0.0473 0.0888 0.594 1.05 0.881 1.25 0.113 0.0876 0.198 1.12 0.943 1.33 0.00646 0.0898 0.943 1.01 0.844 1.2 ukb-melanoma-gwas-catalog all 737.3 Kyphoscoliosis and scoliosis Musculoskeletal Both 1.04 0.973 1.1 0.262 1064 10640 FALSE 0.581698708680255 0.0361 0.0322 0.0793 0.0914 0.386 1.08 0.905 1.3 0.113 0.0908 0.212 1.12 0.937 1.34 0.00284 0.0932 0.976 1 0.835 1.2 ukb-melanoma-gwas-catalog all 738 Other acquired musculoskeletal deformity Musculoskeletal Both 1.01 0.96 1.05 0.81 1921 19210 FALSE 0.0915149811213502 0.00577 0.024 0.00523 0.0679 0.939 1.01 0.88 1.15 0.0575 0.0672 0.393 1.06 0.928 1.21 -0.0177 0.0685 0.797 0.982 0.859 1.12 ukb-melanoma-gwas-catalog all 738.4 Acquired spondylolisthesis Musculoskeletal Both 1.02 0.964 1.07 0.534 1520 15200 FALSE 0.272458742971444 0.0167 0.027 -0.00851 0.0767 0.912 0.992 0.853 1.15 0.0808 0.0753 0.283 1.08 0.935 1.26 -0.0146 0.0771 0.85 0.986 0.847 1.15 ukb-melanoma-gwas-catalog all 739 Contracture of joint Musculoskeletal Both 1.03 0.937 1.13 0.546 489 4890 FALSE 0.262807357295263 0.0286 0.0474 -0.0738 0.136 0.588 0.929 0.71 1.21 0.048 0.133 0.718 1.05 0.807 1.36 0.0699 0.132 0.598 1.07 0.827 1.39 ukb-melanoma-gwas-catalog all 740 Osteoarthrosis Musculoskeletal Both 1 0.992 1.02 0.506 27860 232406 FALSE 0.295849483160201 0.00424 0.00637 0.0229 0.018 0.204 1.02 0.988 1.06 0.0167 0.018 0.354 1.02 0.982 1.05 0.0111 0.0181 0.54 1.01 0.976 1.05 ukb-melanoma-gwas-catalog all 740.1 Osteoarthritis; localized Musculoskeletal Both 1 0.986 1.02 0.859 17461 169819 FALSE 0.0660068361687577 0.00141 0.00797 0.0115 0.0225 0.609 1.01 0.968 1.06 -0.0112 0.0226 0.621 0.989 0.946 1.03 0.00968 0.0226 0.668 1.01 0.966 1.06 ukb-melanoma-gwas-catalog all 740.2 Osteoarthrosis, generalized Musculoskeletal Both 1.06 0.978 1.16 0.147 599 5990 FALSE 0.832682665251824 0.0622 0.0429 0.00233 0.123 0.985 1 0.787 1.28 -0.0292 0.123 0.813 0.971 0.762 1.24 0.132 0.119 0.269 1.14 0.903 1.44 ukb-melanoma-gwas-catalog all 740.9 Osteoarthrosis NOS Musculoskeletal Both 1.01 0.992 1.03 0.277 12302 123014 FALSE 0.557520230935551 0.0103 0.00949 0.0381 0.0269 0.157 1.04 0.985 1.1 0.0718 0.0268 0.0073 1.07 1.02 1.13 0.0128 0.0272 0.637 1.01 0.96 1.07 ukb-melanoma-gwas-catalog all 740.11 Osteoarthrosis, localized, primary Musculoskeletal Both 1 0.978 1.02 0.969 8997 89952 FALSE 0.0136762229492347 -0.000427 0.0111 -0.0095 0.0313 0.762 0.991 0.932 1.05 -0.000448 0.0313 0.989 1 0.94 1.06 -0.00296 0.0314 0.925 0.997 0.938 1.06 ukb-melanoma-gwas-catalog all 740.12 Osteoarthrosis, localized, secondary Musculoskeletal Both 1.06 0.948 1.18 0.312 348 3480 FALSE 0.505845405981557 0.0568 0.0562 0.218 0.158 0.167 1.24 0.912 1.7 -0.00836 0.165 0.96 0.992 0.716 1.37 0.144 0.16 0.368 1.16 0.843 1.59 ukb-melanoma-gwas-catalog all 741 Symptoms and disorders of the joints Musculoskeletal Both 1.01 0.979 1.05 0.47 3624 36240 FALSE 0.327902142064283 0.0126 0.0175 0.0165 0.0496 0.739 1.02 0.922 1.12 0.0459 0.0494 0.353 1.05 0.95 1.15 0.0207 0.0498 0.677 1.02 0.926 1.13 ukb-melanoma-gwas-catalog all 741.1 Ankylosis of joint Musculoskeletal Both 1.08 0.879 1.32 0.466 102 1020 FALSE 0.33161408331 0.0749 0.103 -0.25 0.301 0.407 0.779 0.423 1.42 -0.248 0.308 0.422 0.781 0.417 1.44 0.337 0.267 0.207 1.4 0.829 2.4 ukb-melanoma-gwas-catalog all 741.2 Stiffness of joint Musculoskeletal Both 0.92 0.846 1 0.0508 614 6140 FALSE 1.29413628771608 -0.0833 0.0427 -0.0648 0.116 0.577 0.937 0.746 1.18 -0.108 0.118 0.358 0.897 0.712 1.13 -0.22 0.122 0.0707 0.802 0.631 1.02 ukb-melanoma-gwas-catalog all 741.3 Difficulty in walking Musculoskeletal Both 1.03 0.873 1.21 0.724 155 1550 FALSE 0.140261433802853 0.0295 0.0836 0.49 0.242 0.0432 1.63 1.02 2.66 0.456 0.244 0.0616 1.58 0.978 2.58 0.103 0.261 0.692 1.11 0.66 1.87 ukb-melanoma-gwas-catalog all 741.4 Joint effusions Musculoskeletal Both 1.02 0.969 1.08 0.401 1420 14200 FALSE 0.396855627379818 0.0235 0.0279 0.0523 0.0792 0.509 1.05 0.902 1.23 0.0255 0.0799 0.75 1.03 0.877 1.2 0.07 0.0793 0.377 1.07 0.918 1.25 ukb-melanoma-gwas-catalog all 741.5 Hemarthrosis Musculoskeletal Both 1.07 0.883 1.3 0.47 111 1110 FALSE 0.327902142064283 0.071 0.0982 0.0392 0.289 0.892 1.04 0.584 1.86 0.27 0.277 0.33 1.31 0.758 2.29 0.22 0.284 0.437 1.25 0.711 2.21 ukb-melanoma-gwas-catalog all 741.6 Villonodular synovitis Musculoskeletal Both 1.28 0.969 1.68 0.0766 54 540 FALSE 1.1157712303674 0.245 0.138 0.407 0.411 0.322 1.5 0.664 3.53 0.0324 0.434 0.941 1.03 0.422 2.53 0.595 0.392 0.129 1.81 0.84 4.12 ukb-melanoma-gwas-catalog all 742 Derangement of joint, non-traumatic Musculoskeletal Both 1.01 0.974 1.05 0.556 2906 29060 FALSE 0.254925208417943 0.0115 0.0195 -0.0147 0.0556 0.791 0.985 0.884 1.1 0.0222 0.0552 0.687 1.02 0.918 1.14 0.0432 0.055 0.433 1.04 0.937 1.16 ukb-melanoma-gwas-catalog all 742.1 Loose body in joint Musculoskeletal Both 0.883 0.787 0.989 0.0319 332 3320 TRUE 1.49620931694282 -0.125 0.0581 -0.115 0.154 0.458 0.892 0.657 1.21 -0.189 0.157 0.227 0.828 0.607 1.13 -0.472 0.169 0.00521 0.624 0.445 0.868 ukb-melanoma-gwas-catalog all 742.2 Pathological, developmental or recurrent dislocation Musculoskeletal Both 0.904 0.731 1.12 0.345 96 960 FALSE 0.462180904926726 -0.101 0.107 -0.107 0.284 0.707 0.899 0.509 1.58 -0.428 0.305 0.16 0.652 0.35 1.19 -0.21 0.29 0.47 0.811 0.452 1.44 ukb-melanoma-gwas-catalog all 742.8 Articular cartilage disorder Musculoskeletal Both 0.932 0.849 1.02 0.131 499 4990 FALSE 0.882728704344236 -0.0709 0.047 -0.0856 0.129 0.507 0.918 0.712 1.18 -0.0931 0.13 0.473 0.911 0.705 1.18 -0.198 0.133 0.137 0.82 0.631 1.07 ukb-melanoma-gwas-catalog all 742.9 Other derangement of joint Musculoskeletal Both 1.05 0.999 1.1 0.0527 1995 19950 FALSE 1.27818938478745 0.0456 0.0235 0.0175 0.0682 0.797 1.02 0.89 1.16 0.0868 0.0672 0.197 1.09 0.956 1.24 0.144 0.0665 0.0301 1.16 1.01 1.32 ukb-melanoma-gwas-catalog all 743 Osteoporosis, osteopenia and pathological fracture Musculoskeletal Both 1.02 0.998 1.05 0.0743 7628 76256 FALSE 1.12901118623942 0.0215 0.012 -0.0189 0.0344 0.583 0.981 0.917 1.05 0.0394 0.034 0.247 1.04 0.973 1.11 0.0495 0.034 0.146 1.05 0.983 1.12 ukb-melanoma-gwas-catalog all 743.1 Osteoporosis Musculoskeletal Both 1.03 1 1.05 0.0372 6434 64335 TRUE 1.4294570601181 0.0273 0.0131 0.00985 0.0376 0.793 1.01 0.938 1.09 0.0633 0.0372 0.0886 1.07 0.99 1.15 0.0755 0.0372 0.0421 1.08 1 1.16 ukb-melanoma-gwas-catalog all 743.2 Pathologic fracture Musculoskeletal Both 1.03 0.943 1.13 0.492 523 5230 FALSE 0.30803489723264 0.0316 0.046 -0.0524 0.13 0.687 0.949 0.735 1.23 0.0502 0.127 0.694 1.05 0.818 1.35 -0.0641 0.131 0.625 0.938 0.724 1.21 ukb-melanoma-gwas-catalog all 743.9 Osteopenia or other disorder of bone and cartilage Musculoskeletal Both 0.995 0.926 1.07 0.894 819 8190 FALSE 0.0486624812040823 -0.00487 0.0367 -0.219 0.105 0.0364 0.803 0.654 0.986 -0.131 0.102 0.201 0.877 0.717 1.07 -0.0206 0.1 0.837 0.98 0.805 1.19 ukb-melanoma-gwas-catalog all 743.11 Osteoporosis NOS Musculoskeletal Both 1.02 0.993 1.05 0.139 5577 55767 FALSE 0.856985199745905 0.0208 0.0141 0.0103 0.0402 0.798 1.01 0.934 1.09 0.0522 0.0399 0.19 1.05 0.974 1.14 0.0582 0.0399 0.145 1.06 0.98 1.15 ukb-melanoma-gwas-catalog all 743.13 Other specified osteoporosis Musculoskeletal Both 1.05 0.963 1.15 0.256 530 5299 FALSE 0.59176003468815 0.0517 0.0455 -0.0387 0.132 0.77 0.962 0.741 1.25 0.0452 0.13 0.727 1.05 0.811 1.35 0.152 0.127 0.232 1.16 0.907 1.5 ukb-melanoma-gwas-catalog all 745 Pain in joint Musculoskeletal Both 1.01 0.985 1.03 0.483 7994 79930 FALSE 0.316052869248488 0.00826 0.0118 0.0306 0.0333 0.358 1.03 0.966 1.1 -0.000162 0.0336 0.996 1 0.936 1.07 0.0488 0.0333 0.143 1.05 0.984 1.12 ukb-melanoma-gwas-catalog all 747 Cardiac and circulatory congenital anomalies Congenital Anomalies Both 0.98 0.942 1.02 0.296 2822 28217 FALSE 0.528708288941061 -0.0207 0.0198 -0.0162 0.0554 0.77 0.984 0.883 1.1 -0.0209 0.0555 0.706 0.979 0.878 1.09 -0.0699 0.0563 0.214 0.932 0.835 1.04 ukb-melanoma-gwas-catalog all 747.1 Cardiac congenital anomalies Congenital Anomalies Both 0.977 0.938 1.02 0.251 2645 26447 FALSE 0.600326278518962 -0.0235 0.0205 0.000198 0.057 0.997 1 0.894 1.12 -0.0418 0.0576 0.468 0.959 0.857 1.07 -0.0663 0.0581 0.254 0.936 0.835 1.05 ukb-melanoma-gwas-catalog all 747.2 Congenital anomalies of peripheral vascular system Congenital Anomalies Both 0.96 0.818 1.13 0.614 167 1670 FALSE 0.211831628858832 -0.0408 0.081 -0.497 0.245 0.0424 0.608 0.37 0.983 0.213 0.208 0.305 1.24 0.822 1.87 -0.262 0.232 0.258 0.769 0.483 1.22 ukb-melanoma-gwas-catalog all 747.11 Cardiac shunt/ heart septal defect Congenital Anomalies Both 0.915 0.84 0.996 0.0406 587 5870 TRUE 1.39147396642281 -0.0892 0.0435 -0.207 0.118 0.0794 0.813 0.645 1.02 -0.296 0.121 0.0144 0.744 0.586 0.943 -0.279 0.121 0.0209 0.757 0.596 0.958 ukb-melanoma-gwas-catalog all 747.12 Valvular heart disease/ heart chambers Congenital Anomalies Both 0.997 0.872 1.14 0.968 236 2360 FALSE 0.0141246426916063 -0.00275 0.0683 0.232 0.192 0.227 1.26 0.865 1.85 0.128 0.196 0.516 1.14 0.771 1.68 0.101 0.199 0.611 1.11 0.747 1.64 ukb-melanoma-gwas-catalog all 747.13 Congenital anomalies of great vessels Congenital Anomalies Both 0.982 0.935 1.03 0.454 1823 18227 FALSE 0.342944147142896 -0.0184 0.0246 0.0663 0.0684 0.332 1.07 0.934 1.22 -0.0242 0.0698 0.729 0.976 0.851 1.12 -0.0464 0.0703 0.509 0.955 0.831 1.1 ukb-melanoma-gwas-catalog all 748 Anomalies of respiratory system, congenital Congenital Anomalies Both 1.01 0.752 1.33 0.966 51 510 FALSE 0.0150228735845067 0.00611 0.143 0.265 0.404 0.511 1.3 0.578 3.01 0.275 0.405 0.496 1.32 0.585 3.03 0.123 0.416 0.767 1.13 0.486 2.66 ukb-melanoma-gwas-catalog all 749 Congenital anomalies of face and neck Congenital Anomalies Both 0.94 0.838 1.05 0.292 324 3240 FALSE 0.534617148551582 -0.0615 0.0584 0.115 0.159 0.472 1.12 0.82 1.54 -0.0273 0.165 0.868 0.973 0.703 1.35 -0.138 0.169 0.413 0.871 0.623 1.21 ukb-melanoma-gwas-catalog all 750 Digestive congenital anomalies Congenital Anomalies Both 1.09 1.01 1.18 0.0254 704 7040 TRUE 1.59516628338006 0.0886 0.0396 0.193 0.116 0.0975 1.21 0.965 1.53 0.24 0.115 0.0379 1.27 1.01 1.6 0.277 0.115 0.0159 1.32 1.05 1.65 ukb-melanoma-gwas-catalog all 750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies Both 1.12 0.998 1.25 0.0545 336 3360 FALSE 1.26360349772336 0.11 0.0571 0.224 0.169 0.185 1.25 0.897 1.75 0.209 0.169 0.215 1.23 0.885 1.72 0.373 0.164 0.0231 1.45 1.05 2.01 ukb-melanoma-gwas-catalog all 750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies Both 1.07 0.957 1.19 0.24 364 3640 FALSE 0.619788758288394 0.0646 0.0551 0.207 0.16 0.196 1.23 0.898 1.69 0.241 0.159 0.131 1.27 0.93 1.74 0.209 0.161 0.193 1.23 0.899 1.69 ukb-melanoma-gwas-catalog all 750.13 Congenital anomalies of mouth/tongue Congenital Anomalies Both 1.03 0.89 1.2 0.67 193 1930 FALSE 0.173925197299174 0.0321 0.0751 0.0575 0.222 0.796 1.06 0.682 1.65 0.346 0.209 0.0984 1.41 0.938 2.15 0.13 0.22 0.553 1.14 0.738 1.76 ukb-melanoma-gwas-catalog all 750.21 Congenital anomalies of intestine Congenital Anomalies Both 1.02 0.886 1.16 0.824 229 2290 FALSE 0.0840727883028842 0.0154 0.0692 0.136 0.197 0.49 1.15 0.777 1.7 0.203 0.194 0.294 1.23 0.837 1.8 0.0208 0.202 0.918 1.02 0.684 1.52 ukb-melanoma-gwas-catalog all 750.22 Congenital anomaly of gallbladder, bile ducts, liver, pancreas Congenital Anomalies Both 1.17 0.971 1.42 0.096 118 1180 FALSE 1.01772876696043 0.16 0.0963 0.275 0.293 0.349 1.32 0.736 2.39 0.417 0.286 0.145 1.52 0.865 2.71 0.487 0.284 0.0862 1.63 0.932 2.9 ukb-melanoma-gwas-catalog all 751 Genitourinary congenital anomalies Congenital Anomalies Both 1.04 0.985 1.09 0.16 1590 15900 FALSE 0.795880017344075 0.037 0.0263 0.0189 0.0762 0.804 1.02 0.878 1.18 0.109 0.0749 0.146 1.12 0.963 1.29 0.134 0.0747 0.0719 1.14 0.988 1.32 ukb-melanoma-gwas-catalog all 751.1 Congenital anomalies of genital organs Congenital Anomalies Both 1.02 0.947 1.1 0.58 731 7310 FALSE 0.236572006437063 0.0215 0.0388 -0.0334 0.112 0.764 0.967 0.776 1.2 0.0307 0.11 0.781 1.03 0.83 1.28 0.125 0.109 0.249 1.13 0.916 1.4 ukb-melanoma-gwas-catalog all 751.2 Congenital anomalies of urinary system Congenital Anomalies Both 1.04 0.969 1.12 0.277 850 8500 FALSE 0.557520230935551 0.0391 0.036 0.034 0.104 0.744 1.03 0.843 1.27 0.162 0.102 0.11 1.18 0.964 1.44 0.104 0.103 0.312 1.11 0.907 1.36 ukb-melanoma-gwas-catalog all 751.11 Congenital anomalies of female genital organs Congenital Anomalies Female 1.03 0.933 1.13 0.58 457 4570 FALSE 0.236572006437063 0.0271 0.0491 0.0645 0.139 0.642 1.07 0.812 1.4 -0.0203 0.141 0.886 0.98 0.742 1.29 0.13 0.138 0.347 1.14 0.868 1.5 ukb-melanoma-gwas-catalog all 751.12 Congenital anomalies of male genital organs Congenital Anomalies Male 1.08 0.941 1.23 0.275 228 2280 FALSE 0.560667306169737 0.0753 0.069 -0.0984 0.207 0.634 0.906 0.601 1.36 0.114 0.197 0.565 1.12 0.759 1.66 0.32 0.191 0.0947 1.38 0.946 2.01 ukb-melanoma-gwas-catalog all 751.21 Cystic kidney disease Congenital Anomalies Both 1.14 1.03 1.26 0.00833 426 4260 TRUE 2.07935499859321 0.134 0.0507 0.188 0.153 0.217 1.21 0.894 1.63 0.369 0.148 0.0125 1.45 1.08 1.94 0.345 0.149 0.0205 1.41 1.05 1.9 ukb-melanoma-gwas-catalog all 751.22 Other specified congenital anomalies of kidney Congenital Anomalies Both 0.963 0.861 1.08 0.513 339 3390 FALSE 0.289882634888184 -0.0372 0.0569 -0.0163 0.159 0.918 0.984 0.719 1.35 0.015 0.158 0.924 1.02 0.743 1.39 -0.099 0.163 0.543 0.906 0.657 1.25 ukb-melanoma-gwas-catalog all 752 Nervous system congenital anomalies Congenital Anomalies Both 1.04 0.93 1.16 0.493 336 3360 FALSE 0.30715308072277 0.0392 0.0571 -0.0803 0.166 0.629 0.923 0.664 1.28 0.167 0.156 0.286 1.18 0.869 1.61 -0.00457 0.163 0.978 0.995 0.721 1.37 ukb-melanoma-gwas-catalog all 752.1 Neural tube defects Congenital Anomalies Both 1.03 0.908 1.17 0.63 257 2570 FALSE 0.200659450546418 0.0314 0.0652 -0.0154 0.187 0.934 0.985 0.68 1.43 0.124 0.181 0.495 1.13 0.792 1.62 0.0303 0.186 0.871 1.03 0.714 1.49 ukb-melanoma-gwas-catalog all 752.2 Other specified congenital anomalies of nervous system Congenital Anomalies Both 1.04 0.824 1.31 0.76 80 800 FALSE 0.119186407719209 0.0353 0.116 -0.0576 0.342 0.866 0.944 0.473 1.88 0.324 0.313 0.301 1.38 0.745 2.61 -0.0466 0.334 0.889 0.955 0.486 1.87 ukb-melanoma-gwas-catalog all 752.11 Spina bifida Congenital Anomalies Both 1.11 0.962 1.28 0.152 211 2110 FALSE 0.818156412055227 0.103 0.0719 0.0487 0.212 0.818 1.05 0.69 1.6 0.198 0.205 0.335 1.22 0.814 1.83 0.257 0.204 0.208 1.29 0.865 1.94 ukb-melanoma-gwas-catalog all 753 Congenital anomalies of the eye Congenital Anomalies Both 0.949 0.792 1.14 0.566 131 1310 FALSE 0.247183568811729 -0.0523 0.0911 0.237 0.25 0.342 1.27 0.775 2.09 -0.108 0.268 0.687 0.898 0.525 1.53 0.0542 0.259 0.834 1.06 0.63 1.77 ukb-melanoma-gwas-catalog all 753.1 Congenital cataract and lens anomalies Congenital Anomalies Both 1.01 0.798 1.28 0.927 76 760 FALSE 0.0329202658555029 0.0109 0.118 0.472 0.336 0.161 1.6 0.827 3.18 0.0591 0.362 0.87 1.06 0.511 2.2 0.198 0.346 0.567 1.22 0.61 2.47 ukb-melanoma-gwas-catalog all 754 Congenital musculoskeletal deformities of spine Congenital Anomalies Both 0.982 0.805 1.19 0.852 110 1100 FALSE 0.0695604052332999 -0.0185 0.0996 -0.218 0.274 0.426 0.804 0.463 1.38 -0.0916 0.268 0.733 0.912 0.534 1.55 -0.247 0.277 0.374 0.781 0.447 1.35 ukb-melanoma-gwas-catalog all 755 Congenital anomalies of limbs Congenital Anomalies Both 0.95 0.862 1.05 0.303 449 4490 FALSE 0.518557371497695 -0.0511 0.0496 -0.0771 0.137 0.574 0.926 0.707 1.21 -0.141 0.14 0.315 0.869 0.659 1.14 -0.0766 0.138 0.579 0.926 0.705 1.22 ukb-melanoma-gwas-catalog all 755.1 Congenital deformities of feet Congenital Anomalies Both 1.05 0.913 1.21 0.472 210 2100 FALSE 0.326058001365912 0.0521 0.0723 0.177 0.207 0.392 1.19 0.794 1.8 0.0793 0.213 0.71 1.08 0.71 1.65 0.27 0.206 0.19 1.31 0.874 1.97 ukb-melanoma-gwas-catalog all 755.6 Other congenital anomalies of lower limb, including pelvic girdle Congenital Anomalies Both 0.84 0.714 0.987 0.0333 162 1620 TRUE 1.47755576649368 -0.175 0.082 -0.3 0.22 0.172 0.741 0.478 1.14 -0.314 0.222 0.157 0.73 0.469 1.13 -0.469 0.233 0.0438 0.626 0.391 0.986 ukb-melanoma-gwas-catalog all 755.61 Congenital hip dysplasia and deformity Congenital Anomalies Both 0.792 0.648 0.966 0.0204 107 1070 TRUE 1.6903698325741 -0.234 0.101 -0.63 0.277 0.023 0.532 0.303 0.914 -0.446 0.265 0.0921 0.64 0.375 1.08 -0.602 0.279 0.0306 0.548 0.31 0.942 ukb-melanoma-gwas-catalog all 756 Other congenital musculoskeletal anomalies Congenital Anomalies Both 1.02 0.94 1.11 0.594 593 5930 FALSE 0.226213555018806 0.023 0.0431 -0.0763 0.124 0.537 0.927 0.726 1.18 0.0505 0.12 0.674 1.05 0.831 1.33 0.0154 0.122 0.899 1.02 0.8 1.29 ukb-melanoma-gwas-catalog all 756.3 Congenital anomalies of muscle, tendon, fascia, and connective tissue Congenital Anomalies Both 1.16 0.921 1.45 0.206 81 810 FALSE 0.686132779630847 0.144 0.114 -0.409 0.354 0.249 0.665 0.319 1.34 0.0692 0.316 0.827 1.07 0.57 2.02 0.263 0.306 0.39 1.3 0.711 2.41 ukb-melanoma-gwas-catalog all 756.5 Congenital osteodystrophies Congenital Anomalies Both 0.99 0.896 1.09 0.835 436 4360 FALSE 0.0783135245163979 -0.0104 0.0503 -0.183 0.143 0.202 0.833 0.628 1.1 -0.029 0.138 0.833 0.971 0.741 1.27 -0.0884 0.14 0.529 0.915 0.694 1.21 ukb-melanoma-gwas-catalog all 758 Chromosomal anomalies and genetic disorders Congenital Anomalies Both 1.04 0.895 1.21 0.607 189 1890 FALSE 0.216811308924742 0.0389 0.0757 0.095 0.216 0.66 1.1 0.718 1.69 0.154 0.213 0.468 1.17 0.766 1.78 0.0524 0.217 0.809 1.05 0.685 1.62 ukb-melanoma-gwas-catalog all 758.1 Chromosomal anomalies Congenital Anomalies Both 0.969 0.789 1.19 0.759 100 1000 FALSE 0.11975822410452 -0.0318 0.103 0.231 0.283 0.415 1.26 0.72 2.23 0.0133 0.295 0.964 1.01 0.561 1.83 -0.0896 0.3 0.765 0.914 0.5 1.66 ukb-melanoma-gwas-catalog all 759 Other and unspecified congenital anomalies Congenital Anomalies Both 1.08 0.945 1.24 0.254 233 2330 FALSE 0.595166283380062 0.0783 0.0686 0.174 0.209 0.404 1.19 0.788 1.8 0.498 0.196 0.0111 1.65 1.12 2.44 0.292 0.204 0.152 1.34 0.896 2.01 ukb-melanoma-gwas-catalog all 759.1 Anomalies of endocrine glands, congenital Congenital Anomalies Both 1.02 0.832 1.24 0.866 105 1050 FALSE 0.0624821079826534 0.0171 0.101 0.375 0.302 0.214 1.46 0.801 2.69 0.589 0.293 0.0446 1.8 1.02 3.28 0.211 0.312 0.499 1.24 0.662 2.33 ukb-melanoma-gwas-catalog all 760 Back pain Symptoms Both 0.997 0.978 1.02 0.796 11163 111617 FALSE 0.0990869322623309 -0.00257 0.00996 -0.0123 0.028 0.66 0.988 0.935 1.04 -0.0456 0.0282 0.106 0.955 0.904 1.01 -0.00483 0.0281 0.863 0.995 0.942 1.05 ukb-melanoma-gwas-catalog all 761 Cervicalgia Symptoms Both 1 0.956 1.05 0.866 1792 17920 FALSE 0.0624821079826534 0.0042 0.0248 0.0194 0.071 0.785 1.02 0.887 1.17 0.106 0.0697 0.129 1.11 0.97 1.27 0.0382 0.0712 0.591 1.04 0.903 1.19 ukb-melanoma-gwas-catalog all 764 Sciatica Symptoms Both 0.978 0.938 1.02 0.31 2378 23780 FALSE 0.508638306165727 -0.0219 0.0216 0.0541 0.0602 0.369 1.06 0.938 1.19 -3.14e-05 0.061 1 1 0.887 1.13 -0.0466 0.0618 0.451 0.954 0.845 1.08 ukb-melanoma-gwas-catalog all 766 Neuralgia, neuritis, and radiculitis NOS Symptoms Both 0.94 0.885 0.998 0.0427 1182 11820 TRUE 1.36957212497498 -0.062 0.0306 -0.147 0.0839 0.0791 0.863 0.732 1.02 -0.197 0.0851 0.0208 0.822 0.695 0.971 -0.207 0.0856 0.0157 0.813 0.687 0.962 ukb-melanoma-gwas-catalog all 770 Myalgia and myositis unspecified Symptoms Both 1.08 0.996 1.17 0.0603 642 6420 FALSE 1.21968268785985 0.0778 0.0414 -0.157 0.124 0.203 0.854 0.67 1.09 0.155 0.115 0.18 1.17 0.931 1.47 0.146 0.116 0.209 1.16 0.921 1.45 ukb-melanoma-gwas-catalog all 771 Musculoskeletal symptoms referable to limbs Symptoms Both 1 0.933 1.07 0.988 874 8732 FALSE 0.00524305541237188 0.000512 0.0355 0.0234 0.0995 0.814 1.02 0.842 1.24 -0.0163 0.1 0.871 0.984 0.808 1.2 -0.0228 0.101 0.821 0.977 0.802 1.19 ukb-melanoma-gwas-catalog all 772 Symptoms of the muscles Symptoms Both 1.04 0.96 1.13 0.338 676 6760 FALSE 0.471083299722345 0.0387 0.0405 -0.00984 0.116 0.932 0.99 0.788 1.24 0.0887 0.114 0.435 1.09 0.874 1.37 0.0148 0.115 0.898 1.01 0.809 1.27 ukb-melanoma-gwas-catalog all 773 Pain in limb Symptoms Both 1.02 0.989 1.04 0.249 6290 62896 FALSE 0.603800652904264 0.0153 0.0133 0.0153 0.0375 0.684 1.02 0.943 1.09 -0.0261 0.0379 0.491 0.974 0.905 1.05 0.0532 0.0373 0.154 1.05 0.98 1.13 ukb-melanoma-gwas-catalog all 780 Hypothermia/Chills Symptoms Both 0.959 0.82 1.12 0.599 172 1720 FALSE 0.222573177610689 -0.0418 0.0796 -0.409 0.224 0.0676 0.664 0.423 1.03 -0.193 0.212 0.361 0.824 0.541 1.25 -0.352 0.22 0.11 0.704 0.453 1.08 ukb-melanoma-gwas-catalog all 781 Symptoms involving nervous and musculoskeletal systems Symptoms Both 1.01 0.964 1.06 0.643 1880 18800 FALSE 0.191789027075778 0.0112 0.0242 0.0892 0.069 0.196 1.09 0.955 1.25 0.0597 0.0695 0.39 1.06 0.926 1.22 0.1 0.0691 0.146 1.11 0.966 1.27 ukb-melanoma-gwas-catalog all 783 Fever of unknown origin Symptoms Both 1.01 0.973 1.04 0.72 3930 39300 FALSE 0.142667503568732 0.00601 0.0168 -0.018 0.0471 0.703 0.982 0.895 1.08 -0.0214 0.0472 0.651 0.979 0.892 1.07 -0.0331 0.0475 0.486 0.967 0.881 1.06 ukb-melanoma-gwas-catalog all 785 Abdominal pain Symptoms Both 1.01 0.999 1.02 0.0914 40170 302301 FALSE 1.03905380426617 0.00901 0.00534 0.00271 0.0152 0.858 1 0.973 1.03 0.00655 0.0151 0.666 1.01 0.977 1.04 0.0205 0.0151 0.175 1.02 0.991 1.05 ukb-melanoma-gwas-catalog all 788 Syncope and collapse Symptoms Both 1.02 0.993 1.04 0.172 9112 91099 FALSE 0.764471553092451 0.0151 0.011 0.00198 0.0314 0.95 1 0.942 1.07 0.0285 0.0312 0.361 1.03 0.968 1.09 0.0481 0.0312 0.123 1.05 0.987 1.12 ukb-melanoma-gwas-catalog all 789 Nausea and vomiting Symptoms Both 1.02 1 1.04 0.0345 11612 116110 TRUE 1.46218090492673 0.0207 0.00977 0.0202 0.0277 0.465 1.02 0.966 1.08 0.0332 0.0277 0.23 1.03 0.979 1.09 0.038 0.0277 0.171 1.04 0.984 1.1 ukb-melanoma-gwas-catalog all 790 Nonspecific findings on examination of blood Symptoms Both 0.979 0.828 1.16 0.803 150 1500 FALSE 0.095284454721319 -0.0213 0.0851 -0.28 0.236 0.236 0.756 0.471 1.2 -0.407 0.245 0.0966 0.665 0.406 1.08 -0.055 0.225 0.807 0.946 0.605 1.48 ukb-melanoma-gwas-catalog all 791 Gangrene Symptoms Both 0.929 0.851 1.01 0.103 553 5530 FALSE 0.987162775294828 -0.0731 0.0448 -0.207 0.124 0.0947 0.813 0.637 1.04 -0.201 0.124 0.104 0.818 0.641 1.04 -0.187 0.124 0.131 0.829 0.649 1.06 ukb-melanoma-gwas-catalog all 792 Abnormal Papanicolaou smear of cervix and cervical HPV Symptoms Female 1.19 0.965 1.46 0.0996 98 966 FALSE 1.0017406615763 0.172 0.105 0.147 0.314 0.639 1.16 0.619 2.19 0.253 0.312 0.418 1.29 0.695 2.42 0.435 0.3 0.147 1.54 0.858 2.84 ukb-melanoma-gwas-catalog all 793 Nonspecific abnormal findings on radiological and other examination of musculoskeletal system Symptoms Both 0.888 0.741 1.06 0.192 134 1340 FALSE 0.71669877129645 -0.118 0.0909 -0.000938 0.239 0.997 0.999 0.622 1.6 -0.252 0.252 0.318 0.777 0.469 1.28 -0.335 0.258 0.194 0.715 0.425 1.19 ukb-melanoma-gwas-catalog all 794 Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc) Symptoms Both 1.07 0.885 1.29 0.491 120 1200 FALSE 0.308918507877032 0.0652 0.0945 -0.0814 0.269 0.762 0.922 0.538 1.57 -0.0574 0.267 0.83 0.944 0.554 1.61 0.0225 0.261 0.931 1.02 0.609 1.72 ukb-melanoma-gwas-catalog all 797 Shock Symptoms Both 1.01 0.859 1.2 0.863 156 1560 FALSE 0.0639892042847904 0.0145 0.084 0.0095 0.232 0.967 1.01 0.637 1.6 -0.0227 0.235 0.923 0.978 0.613 1.56 -0.108 0.239 0.651 0.898 0.557 1.44 ukb-melanoma-gwas-catalog all 797.1 Cardiogenic shock Symptoms Both 0.928 0.755 1.14 0.471 102 1020 FALSE 0.326979092871104 -0.0747 0.104 -0.217 0.272 0.426 0.805 0.466 1.38 -0.509 0.294 0.083 0.601 0.33 1.07 -0.404 0.285 0.156 0.668 0.375 1.17 ukb-melanoma-gwas-catalog all 798 Malaise and fatigue Symptoms Both 1.01 0.977 1.05 0.496 3424 34226 FALSE 0.304518323509803 0.0122 0.018 -0.0229 0.0509 0.653 0.977 0.884 1.08 0.00142 0.0507 0.978 1 0.907 1.11 0.0137 0.0508 0.787 1.01 0.918 1.12 ukb-melanoma-gwas-catalog all 798.1 Chronic fatigue syndrome Symptoms Both 0.998 0.917 1.09 0.962 590 5900 FALSE 0.0168249279621871 -0.00204 0.0432 -0.0513 0.123 0.677 0.95 0.745 1.21 0.127 0.119 0.284 1.14 0.9 1.44 -0.0885 0.125 0.477 0.915 0.716 1.17 ukb-melanoma-gwas-catalog all 800 Fracture of lower limb Injuries & Poisonings Both 1.01 0.988 1.04 0.329 7230 72297 FALSE 0.482804102050026 0.0121 0.0124 0.0457 0.035 0.191 1.05 0.977 1.12 0.0046 0.0354 0.897 1 0.937 1.08 0.055 0.0351 0.116 1.06 0.986 1.13 ukb-melanoma-gwas-catalog all 800.1 Fracture of neck of femur Injuries & Poisonings Both 1.01 0.96 1.06 0.744 1813 18130 FALSE 0.128427064454121 0.00807 0.0247 -0.0324 0.0702 0.645 0.968 0.844 1.11 -0.0275 0.0703 0.695 0.973 0.847 1.12 0.0598 0.0691 0.387 1.06 0.927 1.22 ukb-melanoma-gwas-catalog all 800.2 Fracture of unspecified part of femur Injuries & Poisonings Both 0.831 0.708 0.974 0.0217 170 1700 TRUE 1.66354026615147 -0.185 0.0808 -0.0155 0.211 0.941 0.985 0.648 1.5 -0.179 0.221 0.42 0.836 0.538 1.29 -0.434 0.237 0.067 0.648 0.402 1.03 ukb-melanoma-gwas-catalog all 800.3 Fracture of tibia and fibula Injuries & Poisonings Both 1.01 0.963 1.05 0.76 2156 21560 FALSE 0.119186407719209 0.00692 0.0227 0.0964 0.0638 0.131 1.1 0.972 1.25 0.0427 0.0647 0.51 1.04 0.919 1.19 0.0458 0.0649 0.48 1.05 0.922 1.19 ukb-melanoma-gwas-catalog all 800.4 Fracture of patella Injuries & Poisonings Both 1.01 0.938 1.09 0.79 766 7660 FALSE 0.102372908709559 0.0101 0.0379 0.192 0.106 0.0691 1.21 0.985 1.49 -0.0697 0.112 0.534 0.933 0.748 1.16 0.107 0.108 0.32 1.11 0.901 1.38 ukb-melanoma-gwas-catalog all 801 Fracture of ankle and foot Injuries & Poisonings Both 1.05 1 1.09 0.0302 2333 23325 TRUE 1.51999305704285 0.0472 0.0218 0.0755 0.0623 0.225 1.08 0.954 1.22 0.0696 0.0625 0.266 1.07 0.948 1.21 0.127 0.0619 0.0404 1.14 1.01 1.28 ukb-melanoma-gwas-catalog all 801.1 Fracture of foot Injuries & Poisonings Both 1.07 1.02 1.12 0.00999 1838 18375 TRUE 2.00043451177402 0.0631 0.0245 0.0637 0.0707 0.367 1.07 0.928 1.22 0.0964 0.0703 0.171 1.1 0.959 1.26 0.148 0.0697 0.034 1.16 1.01 1.33 ukb-melanoma-gwas-catalog all 802 Fracture of pelvis Injuries & Poisonings Both 1.03 0.956 1.11 0.417 722 7220 FALSE 0.379863945026242 0.0317 0.039 -0.0939 0.114 0.408 0.91 0.728 1.14 0.102 0.109 0.347 1.11 0.895 1.37 0.0603 0.11 0.584 1.06 0.855 1.32 ukb-melanoma-gwas-catalog all 803 Fracture of upper limb Injuries & Poisonings Both 1.02 0.995 1.04 0.129 8480 84788 FALSE 0.889410289700751 0.0173 0.0114 0.0066 0.0323 0.838 1.01 0.945 1.07 -0.00307 0.0324 0.925 0.997 0.935 1.06 0.0369 0.0323 0.253 1.04 0.974 1.11 ukb-melanoma-gwas-catalog all 803.1 Fracture of humerus Injuries & Poisonings Both 0.988 0.94 1.04 0.65 1685 16840 FALSE 0.187086643357144 -0.0116 0.0257 -0.0362 0.0714 0.612 0.964 0.838 1.11 -0.11 0.0729 0.129 0.895 0.776 1.03 -0.0258 0.0717 0.719 0.975 0.847 1.12 ukb-melanoma-gwas-catalog all 803.2 Fracture of radius and ulna Injuries & Poisonings Both 1.02 0.995 1.05 0.106 5214 52138 FALSE 0.97469413473523 0.0236 0.0146 0.0664 0.0414 0.109 1.07 0.985 1.16 0.0571 0.0415 0.169 1.06 0.976 1.15 0.0661 0.0416 0.112 1.07 0.985 1.16 ukb-melanoma-gwas-catalog all 803.3 Fracture of clavicle or scapula Injuries & Poisonings Both 1.05 0.992 1.1 0.0933 1518 15180 FALSE 1.0301183562535 0.0452 0.0269 -0.0101 0.0776 0.896 0.99 0.85 1.15 0.0377 0.0767 0.623 1.04 0.893 1.21 0.114 0.0757 0.132 1.12 0.966 1.3 ukb-melanoma-gwas-catalog all 804 Fracture of hand or wrist Injuries & Poisonings Both 0.99 0.956 1.03 0.595 3349 33490 FALSE 0.22548303427145 -0.00966 0.0182 -0.0408 0.051 0.424 0.96 0.869 1.06 -0.0287 0.0509 0.572 0.972 0.879 1.07 -0.0645 0.0515 0.21 0.938 0.847 1.04 ukb-melanoma-gwas-catalog all 805 Fracture of vertebral column without mention of spinal cord injury Injuries & Poisonings Both 1.03 0.972 1.09 0.338 1359 13590 FALSE 0.471083299722345 0.0273 0.0285 -0.0342 0.0817 0.675 0.966 0.823 1.13 0.0554 0.0801 0.49 1.06 0.903 1.24 0.0478 0.0805 0.553 1.05 0.896 1.23 ukb-melanoma-gwas-catalog all 807 Fracture of ribs Injuries & Poisonings Both 1 0.93 1.08 0.973 778 7780 FALSE 0.0118871597316481 0.00128 0.0377 -0.0784 0.107 0.466 0.925 0.748 1.14 0.0287 0.105 0.785 1.03 0.837 1.26 0.00765 0.106 0.943 1.01 0.818 1.24 ukb-melanoma-gwas-catalog all 809 Fracture of unspecified bones Injuries & Poisonings Both 1.01 0.959 1.07 0.612 1306 13060 FALSE 0.213248577854439 0.0148 0.0291 0.0455 0.0834 0.585 1.05 0.889 1.23 0.136 0.0819 0.0959 1.15 0.976 1.35 0.0375 0.0839 0.655 1.04 0.881 1.22 ukb-melanoma-gwas-catalog all 817 Concussion Injuries & Poisonings Both 1.08 0.947 1.23 0.246 245 2450 FALSE 0.609064892896621 0.0777 0.067 0.0409 0.203 0.84 1.04 0.697 1.56 0.468 0.189 0.0131 1.6 1.1 2.33 0.181 0.198 0.361 1.2 0.811 1.78 ukb-melanoma-gwas-catalog all 818 Intracranial hemorrhage (injury) Injuries & Poisonings Both 0.969 0.885 1.06 0.486 526 5260 FALSE 0.313363730737707 -0.0319 0.0458 -0.055 0.129 0.67 0.946 0.734 1.22 0.00268 0.128 0.983 1 0.78 1.29 -0.0333 0.129 0.797 0.967 0.75 1.25 ukb-melanoma-gwas-catalog all 819 Skull and face fracture and other intercranial injury Injuries & Poisonings Both 1.01 0.973 1.05 0.574 2967 29665 FALSE 0.241088107602026 0.0109 0.0193 -0.0761 0.055 0.167 0.927 0.832 1.03 -0.0112 0.0542 0.836 0.989 0.889 1.1 0.00863 0.0542 0.874 1.01 0.907 1.12 ukb-melanoma-gwas-catalog all 823 Torus fracture Injuries & Poisonings Both 1 0.952 1.05 0.967 1676 16752 FALSE 0.0145735259169983 0.00106 0.0257 0.116 0.0718 0.105 1.12 0.976 1.29 0.00737 0.0738 0.92 1.01 0.872 1.16 0.0259 0.0736 0.725 1.03 0.888 1.19 ukb-melanoma-gwas-catalog all 830 Dislocation Injuries & Poisonings Both 1.05 1.01 1.1 0.0209 2092 20914 TRUE 1.67985371388895 0.0531 0.023 0.105 0.0657 0.109 1.11 0.977 1.26 0.0275 0.067 0.682 1.03 0.901 1.17 0.184 0.065 0.00468 1.2 1.06 1.37 ukb-melanoma-gwas-catalog all 835 Internal derangement of knee Injuries & Poisonings Both 1.01 0.993 1.03 0.264 15259 152537 FALSE 0.578396073130169 0.00952 0.00852 0.0148 0.0241 0.541 1.01 0.968 1.06 0.0286 0.0241 0.236 1.03 0.982 1.08 0.0209 0.0242 0.389 1.02 0.974 1.07 ukb-melanoma-gwas-catalog all 836 Traumatic arthropathy Injuries & Poisonings Both 1.09 1 1.2 0.05 527 5270 FALSE 1.30102999566398 0.0894 0.0456 0.242 0.133 0.0676 1.27 0.983 1.66 0.198 0.134 0.14 1.22 0.937 1.59 0.271 0.132 0.0401 1.31 1.01 1.7 ukb-melanoma-gwas-catalog all 840 Sprains and strains Injuries & Poisonings Both 1.04 0.952 1.15 0.351 496 4960 FALSE 0.454692883534176 0.0439 0.0471 -0.019 0.136 0.889 0.981 0.751 1.28 0.0698 0.133 0.601 1.07 0.825 1.39 0.129 0.132 0.331 1.14 0.877 1.48 ukb-melanoma-gwas-catalog all 850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings Both 1.03 0.998 1.06 0.0736 5327 53270 FALSE 1.1331221856625 0.0258 0.0144 -0.0555 0.0411 0.176 0.946 0.873 1.03 -0.022 0.0408 0.59 0.978 0.903 1.06 0.0405 0.0403 0.314 1.04 0.962 1.13 ukb-melanoma-gwas-catalog all 851 Complications of transplants and reattached limbs Injuries & Poisonings Both 1.18 1 1.38 0.0482 159 1590 TRUE 1.31695296176115 0.162 0.0821 0.482 0.254 0.0576 1.62 0.984 2.71 0.488 0.256 0.0563 1.63 0.987 2.73 0.627 0.253 0.0131 1.87 1.14 3.13 ukb-melanoma-gwas-catalog all 853 Complication of colostomy or enterostomy Injuries & Poisonings Both 0.988 0.901 1.08 0.8 503 5030 FALSE 0.0969100130080564 -0.0119 0.0469 -0.108 0.133 0.416 0.897 0.69 1.17 -0.113 0.134 0.4 0.893 0.686 1.16 0.0458 0.129 0.722 1.05 0.812 1.35 ukb-melanoma-gwas-catalog all 854 Complications of cardiac/vascular device, implant, and graft Injuries & Poisonings Both 1.01 0.96 1.06 0.766 1830 18300 FALSE 0.115771230367396 0.00733 0.0246 -0.0221 0.0697 0.751 0.978 0.853 1.12 -0.00204 0.0695 0.977 0.998 0.871 1.14 0.0193 0.0692 0.781 1.02 0.89 1.17 ukb-melanoma-gwas-catalog all 857 Mechanical complication of unspecified genitourinary device, implant, and graft Injuries & Poisonings Both 1.01 0.952 1.07 0.762 1246 12460 FALSE 0.118045028660399 0.00903 0.0298 0.0045 0.084 0.957 1 0.852 1.18 0.0355 0.0835 0.671 1.04 0.88 1.22 -0.032 0.0849 0.707 0.969 0.82 1.14 ukb-melanoma-gwas-catalog all 858 Complication of internal orthopedic device Injuries & Poisonings Both 0.986 0.951 1.02 0.452 3163 31630 FALSE 0.344861565188618 -0.0141 0.0187 0.0303 0.0517 0.558 1.03 0.931 1.14 -0.125 0.0537 0.0203 0.883 0.795 0.981 -0.0308 0.0526 0.558 0.97 0.875 1.07 ukb-melanoma-gwas-catalog all 859 Complication due to other implant and internal device Injuries & Poisonings Both 1.01 0.973 1.05 0.627 3268 32680 FALSE 0.202732459169284 0.00894 0.0184 -0.0387 0.0523 0.46 0.962 0.868 1.07 -0.00877 0.0521 0.866 0.991 0.895 1.1 0.04 0.0515 0.437 1.04 0.941 1.15 ukb-melanoma-gwas-catalog all 860 Bone marrow or stem cell transplant Neoplasms Both 0.959 0.761 1.21 0.719 80 800 FALSE 0.143271109617117 -0.0417 0.116 0.273 0.298 0.358 1.31 0.731 2.39 -0.394 0.345 0.254 0.674 0.331 1.34 -0.229 0.332 0.49 0.795 0.405 1.54 ukb-melanoma-gwas-catalog all 870 Open wounds of head; neck; and trunk Injuries & Poisonings Both 0.995 0.962 1.03 0.752 3836 38342 FALSE 0.123782159408358 -0.00538 0.017 -0.0433 0.048 0.367 0.958 0.871 1.05 -0.0186 0.0479 0.698 0.982 0.894 1.08 -0.00628 0.0479 0.896 0.994 0.905 1.09 ukb-melanoma-gwas-catalog all 870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings Both 0.978 0.863 1.11 0.726 270 2700 FALSE 0.139063379299906 -0.0223 0.0637 0.0817 0.174 0.639 1.09 0.77 1.53 -0.137 0.184 0.458 0.872 0.606 1.25 -0.0354 0.179 0.843 0.965 0.678 1.37 ukb-melanoma-gwas-catalog all 870.2 Open wound of ear Injuries & Poisonings Both 0.984 0.847 1.14 0.826 195 1950 FALSE 0.0830199526796178 -0.0166 0.0754 -0.294 0.209 0.159 0.745 0.491 1.12 -0.248 0.207 0.23 0.78 0.517 1.17 -0.23 0.207 0.266 0.795 0.527 1.19 ukb-melanoma-gwas-catalog all 870.3 Other open wound of head and face Injuries & Poisonings Both 0.994 0.957 1.03 0.76 2915 29141 FALSE 0.119186407719209 -0.00597 0.0195 -0.0578 0.0554 0.297 0.944 0.847 1.05 0.00119 0.0548 0.983 1 0.899 1.11 0.00457 0.0549 0.934 1 0.902 1.12 ukb-melanoma-gwas-catalog all 870.4 Open wound of nose and sinus Injuries & Poisonings Both 1.12 0.977 1.29 0.101 220 2200 FALSE 0.995678626217357 0.116 0.0706 0.164 0.211 0.438 1.18 0.776 1.79 0.254 0.208 0.222 1.29 0.856 1.95 0.404 0.202 0.0461 1.5 1.01 2.24 ukb-melanoma-gwas-catalog all 870.6 Open wound of neck Injuries & Poisonings Both 0.925 0.823 1.04 0.186 313 3130 FALSE 0.730487055782084 -0.0784 0.0593 -0.0571 0.16 0.721 0.945 0.689 1.29 -0.0971 0.161 0.548 0.907 0.66 1.25 -0.348 0.172 0.043 0.706 0.501 0.989 ukb-melanoma-gwas-catalog all 871 Open wounds of extremities Injuries & Poisonings Both 0.985 0.954 1.02 0.337 4216 42160 FALSE 0.472370099128661 -0.0156 0.0162 -0.0453 0.0454 0.319 0.956 0.874 1.04 -0.0527 0.0456 0.247 0.949 0.868 1.04 -0.0517 0.0457 0.258 0.95 0.868 1.04 ukb-melanoma-gwas-catalog all 871.1 Open wound of hand except finger(s) Injuries & Poisonings Both 1.23 0.928 1.64 0.14 53 530 FALSE 0.853871964321762 0.211 0.143 0.265 0.42 0.528 1.3 0.562 3.11 0.291 0.414 0.483 1.34 0.584 3.17 0.596 0.433 0.169 1.82 0.767 4.5 ukb-melanoma-gwas-catalog all 871.2 Open wound of finger(s) Injuries & Poisonings Both 1.02 0.818 1.26 0.877 91 910 FALSE 0.0570004066339595 0.0169 0.109 0.404 0.318 0.203 1.5 0.801 2.87 0.5 0.312 0.11 1.65 0.893 3.12 0.106 0.339 0.755 1.11 0.562 2.21 ukb-melanoma-gwas-catalog all 871.3 Open wound of foot except toe(s) alone Injuries & Poisonings Both 0.862 0.737 1.01 0.0612 179 1790 FALSE 1.21324857785444 -0.148 0.0791 -0.145 0.212 0.494 0.865 0.568 1.31 -0.0642 0.209 0.758 0.938 0.62 1.42 -0.453 0.23 0.0486 0.636 0.4 0.997 ukb-melanoma-gwas-catalog all 872 Traumatic amputation Injuries & Poisonings Both 1 0.91 1.1 0.999 476 4760 FALSE 0.000434511774017692 4.09e-05 0.0481 -0.0903 0.137 0.509 0.914 0.698 1.2 -0.00678 0.134 0.96 0.993 0.763 1.29 -0.0295 0.135 0.827 0.971 0.744 1.27 ukb-melanoma-gwas-catalog all 873 Broken tooth Injuries & Poisonings Both 0.939 0.82 1.08 0.366 229 2290 FALSE 0.436518914605589 -0.0624 0.069 -0.543 0.202 0.00732 0.581 0.387 0.863 -0.0966 0.18 0.592 0.908 0.636 1.29 -0.315 0.19 0.0981 0.73 0.499 1.06 ukb-melanoma-gwas-catalog all 874 Complication of amputation stump Injuries & Poisonings Both 1.12 0.954 1.31 0.167 172 1720 FALSE 0.777283528852417 0.11 0.0797 0.236 0.228 0.3 1.27 0.808 2 -0.0285 0.243 0.907 0.972 0.598 1.58 0.367 0.223 0.1 1.44 0.932 2.26 ukb-melanoma-gwas-catalog all 905 Late effects of musculoskeletal and connective tissue injuries Injuries & Poisonings Both 0.95 0.806 1.12 0.535 158 1580 FALSE 0.271646217978772 -0.0516 0.0833 -0.0243 0.223 0.913 0.976 0.627 1.52 -0.392 0.244 0.108 0.676 0.414 1.09 -0.081 0.227 0.722 0.922 0.587 1.45 ukb-melanoma-gwas-catalog all 907 Injuries to the nervous system Injuries & Poisonings Both 0.97 0.916 1.03 0.293 1315 13150 FALSE 0.533132379645891 -0.0305 0.029 -0.0745 0.081 0.358 0.928 0.792 1.09 -0.0267 0.0802 0.739 0.974 0.832 1.14 -0.135 0.0826 0.103 0.874 0.743 1.03 ukb-melanoma-gwas-catalog all 915 Superficial injury without mention of infection Injuries & Poisonings Both 1.03 0.997 1.06 0.081 4278 42778 FALSE 1.09151498112135 0.0281 0.0161 0.0265 0.046 0.565 1.03 0.938 1.12 0.0443 0.0458 0.334 1.05 0.955 1.14 0.0918 0.0455 0.0438 1.1 1 1.2 ukb-melanoma-gwas-catalog all 916 Contusion Injuries & Poisonings Both 0.957 0.907 1.01 0.111 1484 14840 FALSE 0.954677021213343 -0.0436 0.0274 -0.0706 0.0769 0.358 0.932 0.801 1.08 0.0486 0.0749 0.516 1.05 0.906 1.22 -0.152 0.0787 0.0537 0.859 0.736 1 ukb-melanoma-gwas-catalog all 930 Allergic reaction to food Injuries & Poisonings Both 1.02 0.873 1.18 0.823 183 1830 FALSE 0.0846001647877302 0.0172 0.0773 -0.184 0.225 0.412 0.832 0.531 1.3 0.0209 0.214 0.922 1.02 0.669 1.56 -0.0163 0.215 0.939 0.984 0.643 1.51 ukb-melanoma-gwas-catalog all 938 Dermatitis due to solar radiation Injuries & Poisonings Both 1.21 1.09 1.35 0.000236 390 3900 TRUE 3.62708799702989 0.194 0.0527 0.209 0.159 0.19 1.23 0.901 1.69 0.299 0.157 0.0569 1.35 0.991 1.84 0.415 0.154 0.00686 1.51 1.12 2.06 ukb-melanoma-gwas-catalog all 938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings Both 1.23 1.08 1.4 0.00173 253 2530 TRUE 2.7619538968712 0.205 0.0655 0.243 0.2 0.224 1.27 0.86 1.9 0.427 0.193 0.0274 1.53 1.05 2.26 0.42 0.194 0.0304 1.52 1.04 2.24 ukb-melanoma-gwas-catalog all 939 Atopic/contact dermatitis due to other or unspecified Dermatologic Both 1.03 0.984 1.08 0.214 2105 21050 FALSE 0.669586226650809 0.0285 0.0229 -0.0772 0.0657 0.24 0.926 0.814 1.05 -0.0496 0.0654 0.448 0.952 0.837 1.08 0.1 0.0634 0.114 1.11 0.976 1.25 ukb-melanoma-gwas-catalog all 941 Adverse reaction to serum or vaccine Injuries & Poisonings Both 0.892 0.778 1.02 0.0999 225 2250 FALSE 1.00043451177402 -0.115 0.0696 0.142 0.183 0.436 1.15 0.805 1.66 -0.396 0.209 0.0576 0.673 0.443 1.01 -0.178 0.197 0.367 0.837 0.566 1.23 ukb-melanoma-gwas-catalog all 942 Infusion and transfusion reaction Injuries & Poisonings Both 0.865 0.703 1.06 0.16 104 1040 FALSE 0.795880017344075 -0.145 0.103 -0.189 0.278 0.496 0.827 0.473 1.44 -0.0342 0.267 0.898 0.966 0.568 1.64 -0.539 0.303 0.0755 0.584 0.314 1.06 ukb-melanoma-gwas-catalog all 946 Anaphylactic shock NOS Injuries & Poisonings Both 1.03 0.947 1.13 0.46 551 5510 FALSE 0.337242168318426 0.033 0.0446 0.237 0.129 0.0669 1.27 0.984 1.64 0.225 0.13 0.0824 1.25 0.971 1.62 0.198 0.131 0.131 1.22 0.943 1.58 ukb-melanoma-gwas-catalog all 947 Urticaria Injuries & Poisonings Both 1.05 0.941 1.16 0.401 373 3730 FALSE 0.396855627379818 0.0456 0.0542 0.194 0.157 0.217 1.21 0.891 1.66 0.253 0.156 0.105 1.29 0.949 1.75 0.181 0.159 0.254 1.2 0.877 1.64 ukb-melanoma-gwas-catalog all 949 Allergies, other Injuries & Poisonings Both 1.08 0.978 1.2 0.121 399 3990 FALSE 0.91721462968355 0.0813 0.0525 0.161 0.154 0.296 1.17 0.868 1.59 0.26 0.151 0.0861 1.3 0.964 1.75 0.232 0.152 0.127 1.26 0.935 1.7 ukb-melanoma-gwas-catalog all 952 Spinal cord injury without evidence of spinal bone injury Injuries & Poisonings Both 1.08 0.974 1.19 0.146 423 4230 FALSE 0.835647144215563 0.0742 0.051 0.106 0.15 0.478 1.11 0.828 1.5 0.264 0.145 0.0692 1.3 0.979 1.73 0.189 0.147 0.201 1.21 0.904 1.62 ukb-melanoma-gwas-catalog all 957 Injury to other and unspecified nerves Injuries & Poisonings Both 1 0.885 1.14 0.962 270 2700 FALSE 0.0168249279621871 0.00306 0.0637 -0.0177 0.182 0.923 0.982 0.685 1.41 0.151 0.177 0.392 1.16 0.822 1.65 0.0145 0.182 0.937 1.01 0.708 1.45 ukb-melanoma-gwas-catalog all 958 Certain early complications of trauma or procedure Injuries & Poisonings Both 0.939 0.856 1.03 0.182 497 4970 FALSE 0.739928612014925 -0.0629 0.0472 0.139 0.128 0.277 1.15 0.894 1.48 -0.129 0.136 0.342 0.879 0.672 1.15 -0.0888 0.134 0.509 0.915 0.702 1.19 ukb-melanoma-gwas-catalog all 958.1 Postoperative shock Injuries & Poisonings Both 0.985 0.747 1.3 0.914 56 560 FALSE 0.0390538042661686 -0.0149 0.138 0.257 0.383 0.503 1.29 0.602 2.84 0.348 0.382 0.362 1.42 0.664 3.1 -0.166 0.415 0.69 0.847 0.362 1.96 ukb-melanoma-gwas-catalog all 958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings Both 0.922 0.724 1.17 0.502 74 740 FALSE 0.299296282854981 -0.0811 0.121 0.422 0.333 0.204 1.53 0.792 3.01 0.21 0.345 0.543 1.23 0.619 2.49 -0.0822 0.362 0.82 0.921 0.442 1.91 ukb-melanoma-gwas-catalog all 960 Poisoning by antibiotics Injuries & Poisonings Both 0.993 0.978 1.01 0.346 18183 181830 FALSE 0.460923901207223 -0.00736 0.00781 0.0179 0.022 0.415 1.02 0.975 1.06 0.00182 0.0221 0.934 1 0.959 1.05 -0.00183 0.0221 0.934 0.998 0.956 1.04 ukb-melanoma-gwas-catalog all 960.2 Allergy/adverse effect of penicillin Injuries & Poisonings Both 0.99 0.974 1.01 0.239 15871 158710 FALSE 0.621602099051862 -0.00983 0.00836 0.00563 0.0235 0.811 1.01 0.96 1.05 -0.013 0.0236 0.582 0.987 0.942 1.03 -0.0138 0.0237 0.561 0.986 0.942 1.03 ukb-melanoma-gwas-catalog all 961 Poisoning by other anti-infectives Injuries & Poisonings Both 0.953 0.861 1.05 0.346 420 4200 FALSE 0.460923901207223 -0.0483 0.0513 0.0724 0.141 0.608 1.08 0.815 1.42 -0.0363 0.145 0.802 0.964 0.725 1.28 -0.111 0.148 0.45 0.894 0.668 1.2 ukb-melanoma-gwas-catalog all 962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings Both 1.05 0.949 1.17 0.32 382 3820 FALSE 0.494850021680094 0.0531 0.0535 -0.0184 0.151 0.903 0.982 0.729 1.32 -0.157 0.155 0.312 0.855 0.629 1.16 0.106 0.147 0.47 1.11 0.833 1.49 ukb-melanoma-gwas-catalog all 962.3 Hormones and synthetic substitutes causing adverse effects in therapeutic use Injuries & Poisonings Both 1.07 0.957 1.19 0.24 364 3640 FALSE 0.619788758288394 0.0644 0.0548 0.0172 0.155 0.912 1.02 0.749 1.38 -0.119 0.159 0.457 0.888 0.648 1.22 0.142 0.152 0.35 1.15 0.855 1.55 ukb-melanoma-gwas-catalog all 963 Poisoning by primarily systemic agents Injuries & Poisonings Both 0.924 0.805 1.06 0.256 226 2260 FALSE 0.59176003468815 -0.079 0.0696 0.0365 0.194 0.851 1.04 0.706 1.52 0.161 0.19 0.396 1.17 0.809 1.71 -0.191 0.207 0.357 0.826 0.546 1.24 ukb-melanoma-gwas-catalog all 964 Poisoning by agents primarily affecting blood constituents Injuries & Poisonings Both 0.998 0.884 1.13 0.98 288 2880 FALSE 0.00877392430750515 -0.00155 0.0616 0.0365 0.171 0.831 1.04 0.741 1.45 -0.0673 0.174 0.699 0.935 0.663 1.32 -0.114 0.175 0.514 0.892 0.63 1.26 ukb-melanoma-gwas-catalog all 964.1 Anticoagulants causing adverse effects Injuries & Poisonings Both 1.01 0.892 1.14 0.886 278 2780 FALSE 0.0525662781129492 0.00896 0.0627 0.0498 0.175 0.775 1.05 0.745 1.48 -0.0264 0.177 0.881 0.974 0.687 1.38 -0.0847 0.179 0.636 0.919 0.645 1.31 ukb-melanoma-gwas-catalog all 965 Poisoning by analgesics, antipyretics, and antirheumatics Injuries & Poisonings Both 0.982 0.956 1.01 0.172 6135 61345 FALSE 0.764471553092451 -0.0184 0.0135 -0.0542 0.0375 0.148 0.947 0.88 1.02 -0.0806 0.0377 0.0328 0.923 0.857 0.993 -0.0807 0.0379 0.0332 0.922 0.856 0.994 ukb-melanoma-gwas-catalog all 965.1 Opiates and related narcotics causing adverse effects in therapeutic use Injuries & Poisonings Both 1.02 0.918 1.13 0.725 392 3920 FALSE 0.139661993429006 0.0186 0.0529 -0.0356 0.151 0.814 0.965 0.716 1.3 0.0967 0.148 0.513 1.1 0.824 1.47 0.0106 0.15 0.944 1.01 0.751 1.36 ukb-melanoma-gwas-catalog all 965.2 Antirheumatics causing adverse effects in therapeutic use Injuries & Poisonings Both 1.02 0.928 1.12 0.672 477 4765 FALSE 0.172630726946175 0.0204 0.0482 -0.15 0.137 0.273 0.861 0.657 1.13 -0.113 0.135 0.403 0.893 0.684 1.16 -0.019 0.133 0.886 0.981 0.755 1.27 ukb-melanoma-gwas-catalog all 965.3 Salicylates causing adverse effects in therapeutic use Injuries & Poisonings Both 1.02 0.923 1.13 0.669 403 4025 FALSE 0.174573882232177 0.0223 0.0523 0.21 0.145 0.149 1.23 0.927 1.64 0.0167 0.151 0.912 1.02 0.755 1.37 0.00229 0.152 0.988 1 0.743 1.35 ukb-melanoma-gwas-catalog all 966 Poisoning by anticonvulsants and anti-Parkinsonism drugs Injuries & Poisonings Both 0.99 0.904 1.08 0.831 513 5130 FALSE 0.080398976215889 -0.00989 0.0465 0.132 0.13 0.312 1.14 0.883 1.48 0.127 0.131 0.334 1.13 0.878 1.47 -0.02 0.136 0.884 0.98 0.749 1.28 ukb-melanoma-gwas-catalog all 967 Adverse effects of sedatives or other central nervous system depressants and anesthetics Injuries & Poisonings Both 1.02 0.936 1.11 0.668 590 5900 FALSE 0.175223537524454 0.0185 0.0432 0.0345 0.121 0.775 1.04 0.817 1.31 -0.086 0.124 0.488 0.918 0.719 1.17 0.0294 0.121 0.808 1.03 0.812 1.31 ukb-melanoma-gwas-catalog all 969 Poisoning by psychotropic agents Injuries & Poisonings Both 0.975 0.93 1.02 0.287 1960 19589 FALSE 0.542118103266008 -0.0253 0.0238 -0.0408 0.0665 0.54 0.96 0.843 1.09 -0.058 0.0668 0.385 0.944 0.828 1.08 -0.0649 0.0672 0.334 0.937 0.821 1.07 ukb-melanoma-gwas-catalog all 971 Poisoning by drugs primarily affecting the autonomic nervous system Injuries & Poisonings Both 0.968 0.833 1.12 0.667 192 1920 FALSE 0.175874166083451 -0.0326 0.0757 0.176 0.208 0.397 1.19 0.791 1.81 -0.0636 0.219 0.771 0.938 0.607 1.45 0.0728 0.216 0.736 1.08 0.702 1.65 ukb-melanoma-gwas-catalog all 972 Poisoning by agents primarily affecting the cardiovascular system Injuries & Poisonings Both 0.979 0.865 1.11 0.733 282 2820 FALSE 0.134896025358872 -0.0214 0.0626 -0.125 0.173 0.472 0.883 0.626 1.24 -0.0621 0.171 0.716 0.94 0.671 1.32 -0.169 0.178 0.342 0.845 0.593 1.2 ukb-melanoma-gwas-catalog all 972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings Both 0.955 0.764 1.19 0.684 85 850 FALSE 0.164943898279884 -0.0457 0.112 -0.0193 0.299 0.948 0.981 0.54 1.78 -0.401 0.326 0.219 0.669 0.343 1.28 -0.121 0.309 0.694 0.886 0.476 1.64 ukb-melanoma-gwas-catalog all 973 Poisoning by agents primarily affecting the gastrointestinal system Injuries & Poisonings Both 1.1 0.905 1.34 0.324 108 1080 FALSE 0.489454989793388 0.0985 0.1 0.185 0.283 0.513 1.2 0.687 2.12 -0.172 0.305 0.574 0.842 0.454 1.55 0.375 0.277 0.176 1.45 0.843 2.55 ukb-melanoma-gwas-catalog all 974 Poisoning by water, mineral, and uric acid metabolism drugs Injuries & Poisonings Both 0.892 0.722 1.1 0.274 102 1020 FALSE 0.562249437179612 -0.115 0.105 0.379 0.275 0.168 1.46 0.851 2.54 -0.23 0.311 0.461 0.795 0.422 1.48 0.0403 0.296 0.892 1.04 0.575 1.89 ukb-melanoma-gwas-catalog all 975 Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system Injuries & Poisonings Both 1.06 0.82 1.37 0.641 64 640 FALSE 0.193141970481183 0.0602 0.129 0.595 0.394 0.131 1.81 0.836 4.14 0.666 0.394 0.0911 1.95 0.898 4.45 0.56 0.404 0.165 1.75 0.786 4.07 ukb-melanoma-gwas-catalog all 976 Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs Injuries & Poisonings Both 1 0.761 1.31 1 58 580 FALSE 0 7.22e-05 0.136 -0.339 0.375 0.366 0.713 0.33 1.5 -0.494 0.412 0.231 0.61 0.256 1.38 -0.0953 0.359 0.791 0.909 0.442 1.86 ukb-melanoma-gwas-catalog all 977 Personal history of allergy to medicinal agents Injuries & Poisonings Both 1.08 0.943 1.23 0.263 235 2350 FALSE 0.580044251510242 0.0763 0.0681 0.318 0.194 0.101 1.37 0.939 2.02 0.196 0.2 0.327 1.22 0.821 1.81 0.148 0.202 0.463 1.16 0.778 1.73 ukb-melanoma-gwas-catalog all 979 Adverse drug events and drug allergies Injuries & Poisonings Both 1.02 0.946 1.11 0.577 699 6983 FALSE 0.238824186844269 0.0222 0.0398 0.0303 0.111 0.785 1.03 0.828 1.28 0.0095 0.112 0.933 1.01 0.81 1.26 -0.0501 0.114 0.659 0.951 0.761 1.19 ukb-melanoma-gwas-catalog all 981 Toxic effect of (non-ethyl) alcohol and petroleum and other solvents Injuries & Poisonings Both 0.972 0.839 1.12 0.7 201 2010 FALSE 0.154901959985743 -0.0286 0.0741 -0.306 0.215 0.155 0.737 0.479 1.12 -0.0666 0.203 0.743 0.936 0.625 1.4 -0.0235 0.202 0.907 0.977 0.655 1.46 ukb-melanoma-gwas-catalog all 986 Toxic effect of carbon monoxide Injuries & Poisonings Both 0.887 0.695 1.13 0.324 73 730 FALSE 0.489454989793388 -0.12 0.122 -0.0478 0.335 0.886 0.953 0.485 1.86 -0.0586 0.33 0.859 0.943 0.486 1.82 -0.202 0.34 0.552 0.817 0.41 1.61 ukb-melanoma-gwas-catalog all 987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings Both 1.02 0.833 1.24 0.851 106 1060 FALSE 0.0700704399154121 0.0189 0.101 -0.0472 0.287 0.869 0.954 0.537 1.69 0.215 0.273 0.43 1.24 0.723 2.15 -0.147 0.294 0.618 0.863 0.477 1.55 ukb-melanoma-gwas-catalog all 988 Toxic effect of noxious substances eaten as food Injuries & Poisonings Both 0.969 0.798 1.18 0.746 113 1130 FALSE 0.127261172527331 -0.0317 0.098 -0.588 0.289 0.0422 0.555 0.307 0.978 -0.162 0.263 0.537 0.85 0.503 1.43 -0.197 0.261 0.451 0.822 0.488 1.38 ukb-melanoma-gwas-catalog all 989 Toxic effect of other substances, chiefly nonmedicinal as to source Injuries & Poisonings Both 0.963 0.772 1.2 0.733 89 890 FALSE 0.134896025358872 -0.0378 0.111 0.066 0.299 0.826 1.07 0.589 1.95 0.0798 0.298 0.789 1.08 0.598 1.97 -0.318 0.339 0.348 0.727 0.362 1.43 ukb-melanoma-gwas-catalog all 990 Effects radiation NOS Injuries & Poisonings Both 1.02 0.979 1.05 0.391 3122 31220 FALSE 0.407823242604133 0.0161 0.0188 0.0151 0.0533 0.777 1.02 0.914 1.13 0.0346 0.0531 0.515 1.04 0.933 1.15 0.0165 0.0534 0.757 1.02 0.916 1.13 ukb-melanoma-gwas-catalog all 994 Sepsis and SIRS Injuries & Poisonings Both 0.996 0.959 1.03 0.83 3036 30360 FALSE 0.0809219076239261 -0.0041 0.0191 0.0401 0.0535 0.453 1.04 0.937 1.16 0.0348 0.0536 0.517 1.04 0.932 1.15 -0.0579 0.055 0.292 0.944 0.847 1.05 ukb-melanoma-gwas-catalog all 994.2 Sepsis Injuries & Poisonings Both 0.996 0.959 1.03 0.83 3036 30360 FALSE 0.0809219076239261 -0.0041 0.0191 0.0401 0.0535 0.453 1.04 0.937 1.16 0.0348 0.0536 0.517 1.04 0.932 1.15 -0.0579 0.055 0.292 0.944 0.847 1.05 ukb-melanoma-gwas-catalog all 1000 Burns Injuries & Poisonings Both 1.02 0.938 1.11 0.616 582 5813 FALSE 0.210419287835575 0.0219 0.0437 -0.0492 0.126 0.696 0.952 0.743 1.22 0.133 0.121 0.273 1.14 0.9 1.45 0.0535 0.125 0.668 1.05 0.825 1.35 ukb-melanoma-gwas-catalog all 1001 Foreign body injury Injuries & Poisonings Both 1.02 0.958 1.08 0.605 1231 12305 FALSE 0.218244625347531 0.0155 0.03 0.045 0.0846 0.595 1.05 0.886 1.24 0.0042 0.0855 0.961 1 0.849 1.19 0.0659 0.0848 0.437 1.07 0.904 1.26 ukb-melanoma-gwas-catalog all 1002 Symptoms concerning nutrition, metabolism, and development Injuries & Poisonings Both 0.996 0.969 1.02 0.783 5493 54927 FALSE 0.106238237942057 -0.00391 0.0142 0.0103 0.0399 0.796 1.01 0.934 1.09 0.000709 0.04 0.986 1 0.925 1.08 -0.0244 0.0404 0.545 0.976 0.902 1.06 ukb-melanoma-gwas-catalog all 1004 Other signs and symptoms involving emotional state Injuries & Poisonings Both 1.06 0.941 1.19 0.338 301 3010 FALSE 0.471083299722345 0.0578 0.0604 -0.00576 0.171 0.973 0.994 0.71 1.39 0.0195 0.171 0.909 1.02 0.728 1.43 0.0197 0.17 0.908 1.02 0.73 1.43 ukb-melanoma-gwas-catalog all 1005 Other symptoms Injuries & Poisonings Both 1.01 0.952 1.06 0.847 1449 14484 FALSE 0.0721165896692931 0.00533 0.0276 0.0291 0.0782 0.709 1.03 0.883 1.2 -0.00425 0.0789 0.957 0.996 0.853 1.16 0.0619 0.0779 0.427 1.06 0.913 1.24 ukb-melanoma-gwas-catalog all 1006 Crushing injury Injuries & Poisonings Both 0.875 0.769 0.995 0.0404 258 2580 TRUE 1.3936186348894 -0.134 0.0654 -0.0564 0.172 0.744 0.945 0.672 1.33 -0.24 0.181 0.184 0.786 0.549 1.12 -0.411 0.189 0.0301 0.663 0.454 0.961 ukb-melanoma-gwas-catalog all 1007 Injury to blood vessels Injuries & Poisonings Both 0.821 0.722 0.933 0.00252 256 2560 TRUE 2.59859945921846 -0.197 0.0654 -0.27 0.167 0.106 0.764 0.549 1.06 -0.585 0.182 0.00131 0.557 0.387 0.794 -0.762 0.192 6.91e-05 0.467 0.317 0.677 ukb-melanoma-gwas-catalog all 1008 Crushing or internal injury to organs Injuries & Poisonings Both 0.973 0.912 1.04 0.406 1014 10140 FALSE 0.391473966422806 -0.0275 0.0331 -0.0905 0.0928 0.329 0.913 0.761 1.1 -0.0471 0.0919 0.608 0.954 0.796 1.14 -0.0879 0.0931 0.345 0.916 0.763 1.1 ukb-melanoma-gwas-catalog all 1009 Injury, NOS Injuries & Poisonings Both 0.993 0.971 1.02 0.516 8505 85048 FALSE 0.287350298372789 -0.00742 0.0114 -0.0313 0.0321 0.329 0.969 0.91 1.03 -0.0404 0.0322 0.209 0.96 0.902 1.02 -0.0199 0.0322 0.537 0.98 0.92 1.04 ukb-melanoma-gwas-catalog all 1010 Other tests Injuries & Poisonings Both 1.01 0.985 1.04 0.377 5979 59790 FALSE 0.423658649794207 0.012 0.0136 0.0248 0.0387 0.522 1.03 0.95 1.11 0.0552 0.0385 0.152 1.06 0.98 1.14 0.0466 0.0387 0.228 1.05 0.971 1.13 ukb-melanoma-gwas-catalog all 1011 Complications of surgical and medical procedures Injuries & Poisonings Both 0.991 0.97 1.01 0.394 9182 91820 FALSE 0.404503778174426 -0.00936 0.011 -0.017 0.0308 0.58 0.983 0.926 1.04 -0.046 0.031 0.138 0.955 0.899 1.01 -0.0276 0.031 0.372 0.973 0.915 1.03 ukb-melanoma-gwas-catalog all 1012 Late effect Injuries & Poisonings Both 1.03 0.841 1.26 0.78 106 1060 FALSE 0.10790539730952 0.0285 0.102 -0.103 0.31 0.74 0.902 0.482 1.68 0.556 0.277 0.0445 1.74 1.02 3.06 0.174 0.301 0.564 1.19 0.652 2.18 ukb-melanoma-gwas-catalog all 1013 Asphyxia and hypoxemia Injuries & Poisonings Both 1.04 0.925 1.17 0.515 317 3170 FALSE 0.288192770958809 0.0383 0.0588 -0.00138 0.171 0.994 0.999 0.712 1.4 0.179 0.166 0.28 1.2 0.864 1.66 0.0959 0.168 0.569 1.1 0.79 1.54 ukb-melanoma-gwas-catalog all 1014 Effects of heat, cold and air pressure Injuries & Poisonings Both 0.946 0.734 1.22 0.664 66 660 FALSE 0.177831920631982 -0.0553 0.127 0.0246 0.345 0.943 1.02 0.513 2.05 -0.0332 0.354 0.925 0.967 0.473 1.97 -0.101 0.36 0.778 0.904 0.435 1.86 ukb-melanoma-gwas-catalog all 1015 Effects of other external causes Injuries & Poisonings Both 1.02 0.983 1.05 0.357 4237 42370 FALSE 0.447331783887807 0.0149 0.0162 0.00817 0.0459 0.859 1.01 0.921 1.1 0.0198 0.0459 0.666 1.02 0.932 1.12 0.0449 0.0457 0.326 1.05 0.956 1.14 ukb-melanoma-gwas-catalog all 1019 Other ill-defined and unknown causes of morbidity and mortality Injuries & Poisonings Both 1.01 0.998 1.03 0.0852 16056 160552 FALSE 1.0695604052333 0.0143 0.0083 0.0153 0.0236 0.516 1.02 0.97 1.06 0.0313 0.0235 0.184 1.03 0.985 1.08 0.0435 0.0235 0.0645 1.04 0.997 1.09