Departments of Anesthesiology and Biostatistics | University of Michigan

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Skin Cancer PRSweb

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Scores Skin cancer Michigan Genomics Initiative (MGI) PheWAS analysis

Skin cancer — Michigan Genomics Initiative (MGI) PRS PheWAS

PRS model
PRS ID mgi-skin-cancer-fixed-threshold-5e-08Legacy UKB-5E-8Fixed threshold (5e-08)UK Biobank summary statistics

Evaluation cohort: Michigan Genomics Initiative (MGI).

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106 rows visible 15 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 0.953 0.903 – 1.01 0.0813 1500 14936 all phecode
008.5 Bacterial enteritis Infectious Diseases 0.993 0.916 – 1.08 0.859 666 6643 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.983 0.902 – 1.07 0.703 585 5839 all phecode
008.6 Viral Enteritis Infectious Diseases 0.873 0.788 – 0.965 0.00789 433 4330 all phecode
010 Tuberculosis Infectious Diseases 1 0.793 – 1.26 0.984 80 793 all phecode
038 Septicemia Infectious Diseases 0.995 0.939 – 1.05 0.857 1305 12978 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.01 0.901 – 1.13 0.848 320 3178 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.04 0.865 – 1.24 0.696 133 1330 all phecode
038.3 Bacteremia Infectious Diseases 0.971 0.887 – 1.06 0.526 532 5278 all phecode
041 Bacterial infection NOS Infectious Diseases 0.977 0.94 – 1.02 0.234 2913 26150 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.02 0.948 – 1.09 0.654 929 9277 all phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 0.96 0.857 – 1.07 0.481 347 3458 all phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.04 0.922 – 1.17 0.535 301 3010 all phecode
041.2 Streptococcus infection Infectious Diseases 1.01 0.938 – 1.09 0.798 797 7962 all phecode
041.4 E. coli Infectious Diseases 0.911 0.84 – 0.988 0.0251 667 6644 all phecode
041.8 H. pylori Infectious Diseases 1.08 1.03 – 1.13 0.438 82 766 all phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 0.9 0.759 – 1.06 0.216 152 1510 all phecode
053 Herpes zoster Infectious Diseases 0.988 0.91 – 1.07 0.763 663 6615 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.781 0.627 – 0.967 0.0237 102 1019 all phecode
054 Herpes simplex Infectious Diseases 0.973 0.896 – 1.06 0.516 619 6147 all phecode
070 Viral hepatitis Infectious Diseases 0.988 0.89 – 1.09 0.817 402 4013 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.01 0.948 – 1.03 0.964 63 620 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.04 0.924 – 1.17 0.503 308 3071 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.01 0.845 – 1.21 0.875 132 1311 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.02 0.924 – 1.13 0.662 422 4214 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.19 0.935 – 1.49 0.148 70 700 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.18 0.894 – 1.59 0.231 52 520 all phecode
078 Viral warts & HPV Infectious Diseases 1.03 0.978 – 1.08 0.283 1812 17996 all phecode
079 Viral infection Infectious Diseases 0.974 0.924 – 1.03 0.328 1526 14924 all phecode
079.2 Infectious mononucleosis Infectious Diseases 0.944 0.902 – 0.981 0.544 107 1046 all phecode
080 Postoperative infection Infectious Diseases 0.984 0.939 – 1.03 0.514 1946 19388 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 0.963 0.903 – 1.03 0.241 1080 10767 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.08 0.935 – 1.25 0.28 201 2010 all phecode
1000 Burns Injuries & Poisonings 0.939 0.839 – 1.05 0.268 354 3532 all phecode
1001 Foreign body injury Injuries & Poisonings 1.01 0.959 – 1.06 0.739 1707 16964 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 0.99 0.956 – 1.02 0.554 3861 26353 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 0.99 0.896 – 1.03 0.898 139 1373 all phecode
1005 Other symptoms Injuries & Poisonings 1 0.961 – 1.05 0.891 2419 23166 all phecode
1006 Crushing injury Injuries & Poisonings 1.1 0.914 – 1.35 0.217 162 1612 all phecode
1007 Injury to blood vessels Injuries & Poisonings 1.05 0.924 – 1.18 0.476 280 2800 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 0.918 0.84 – 1 0.0597 569 5646 all phecode
1009 Injury, NOS Injuries & Poisonings 0.999 0.967 – 1.03 0.938 4515 26171 all phecode
1010 Other tests Injuries & Poisonings 1 0.977 – 1.02 0.994 11545 19151 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 0.991 0.951 – 1.03 0.648 2557 24998 all phecode
1012 Late effect Injuries & Poisonings 0.985 0.861 – 1.12 0.827 253 2520 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.03 0.979 – 1.08 0.27 1794 17855 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.13 0.891 – 1.42 0.306 71 710 all phecode
1015 Effects of other external causes Injuries & Poisonings 1 0.956 – 1.05 0.982 2084 20811 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.05 0.978 – 1.12 0.186 918 9171 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.06 1.01 – 1.11 0.0249 1707 16828 all phecode
110.1 Dermatophytosis Infectious Diseases 1.06 1.01 – 1.12 0.0274 1585 15622 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.06 0.992 – 1.13 0.0835 925 9188 all phecode
110.12 Althete's foot Infectious Diseases 1.11 1.01 – 1.23 0.0323 411 4088 all phecode
110.13 Dermatophytosis of the body Infectious Diseases 1.04 0.938 – 1.16 0.437 393 3913 all phecode
110.2 Dermatomycoses Infectious Diseases 1.12 0.914 – 1.16 0.16 159 1581 all phecode
1100 Family history Injuries & Poisonings 1.05 0.88 – 1.26 0.571 138 1375 all phecode
112 Candidiasis Infectious Diseases 1.08 1.03 – 1.13 0.00187 1931 19005 all phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.18 1.06 – 1.32 0.00192 362 3620 all phecode
117 Mycoses Infectious Diseases 0.938 0.829 – 1.06 0.309 287 2852 all phecode
117.1 Histoplasmosis Infectious Diseases 1.05 1.02 – 1.1 0.711 52 520 all phecode
117.4 Aspergillosis Infectious Diseases 0.981 0.757 – 1.26 0.882 63 619 all phecode
130 Spirochetal infection Infectious Diseases 1.03 0.72 – 1.06 0.772 67 667 all phecode
132 Infestation (lice, mites) Infectious Diseases 0.801 0.636 – 1 0.0522 96 955 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.994 0.924 – 1.07 0.862 815 8099 all phecode
145 Cancer of mouth Neoplasms 0.989 0.923 – 1.06 0.756 886 8808 all phecode
145.2 Cancer of tongue Neoplasms 0.919 0.83 – 1.02 0.103 417 4154 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.22 1.06 – 1.39 0.00532 218 2162 all phecode
145.4 Cancer of the gums Neoplasms 0.878 0.716 – 1.07 0.202 112 1109 all phecode
145.5 Cancer of the mouth floor Neoplasms 0.986 0.823 – 1.18 0.873 130 1289 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.927 0.862 – 0.997 0.0419 830 8259 all phecode
149.1 Cancer of oropharynx Neoplasms 0.773 0.663 – 0.899 0.000865 204 2021 all phecode
149.2 Cancer of nasopharynx Neoplasms 1.05 0.804 – 1.36 0.714 63 630 all phecode
149.3 Cancer of hypopharynx Neoplasms 0.882 0.654 – 1.18 0.393 53 526 all phecode
149.4 Cancer of larynx Neoplasms 0.935 0.82 – 1.06 0.313 256 2558 all phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 0.955 0.858 – 1.06 0.391 368 3672 all phecode
149.9 Cancer of of nasal cavities Neoplasms 0.919 0.775 – 1.09 0.328 159 1582 all phecode
150 Cancer of esophagus Neoplasms 0.965 0.855 – 1.09 0.557 293 2917 all phecode
151 Cancer of stomach Neoplasms 0.905 0.794 – 1.03 0.128 259 2582 all phecode
153 Colorectal cancer Neoplasms 1.02 0.948 – 1.11 0.523 806 8045 all phecode
153.2 Colon cancer Neoplasms 1.02 0.931 – 1.11 0.696 617 6150 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.03 0.936 – 1.14 0.484 494 4922 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.02 0.903 – 1.15 0.769 296 2960 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.01 0.881 – 1.16 0.872 221 2210 all phecode
157 Pancreatic cancer Neoplasms 0.942 0.836 – 1.06 0.323 313 3130 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.96 0.896 – 1.03 0.242 904 8981 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.949 0.875 – 1.03 0.199 667 6658 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.931 0.772 – 1.12 0.451 123 1225 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.876 0.714 – 1.07 0.192 104 1040 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.936 0.801 – 1.09 0.398 189 1883 all phecode
164 Cancer of intrathoracic organs Neoplasms 1.19 0.937 – 1.23 0.0716 93 930 all phecode
165 Cancer within the respiratory system Neoplasms 0.996 0.928 – 1.07 0.911 851 8499 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.01 0.937 – 1.09 0.75 707 7060 all phecode
170 Cancer of bone and connective tissue Neoplasms 1.05 0.988 – 1.12 0.112 1146 11400 all phecode
170.1 Bone cancer Neoplasms 0.963 0.876 – 1.06 0.426 496 4942 all phecode
170.2 Cancer of connective tissue Neoplasms 1.08 1 – 1.16 0.0396 817 8145 all phecode
172 Skin cancer Neoplasms 1.34 1.3 – 1.39 7.08e-70 4503 22747 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.37 1.3 – 1.43 1.61e-39 1896 16354 all phecode
172.11 Melanomas of skin Neoplasms 1.36 1.3 – 1.43 7.42e-37 1772 15654 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1.39 1.34 – 1.45 3.64e-67 3220 19453 all phecode
172.21 Basal cell carcinoma Neoplasms 1.62 1.53 – 1.72 2.54e-64 1303 11426 all phecode
172.22 Squamous cell carcinoma Neoplasms 1.35 1.26 – 1.45 1.01e-17 836 7436 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.49 1.39 – 1.59 3.79e-31 896 7983 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.2 1.13 – 1.27 1.84e-09 1203 11716 all phecode
174 Breast cancer Neoplasms 1.01 0.968 – 1.06 0.555 2106 11124 all phecode
174.1 Breast cancer [female] Neoplasms 1.01 0.961 – 1.06 0.727 2025 10599 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.01 0.96 – 1.06 0.755 1963 10559 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.15 0.937 – 1.41 0.174 103 1019 all phecode
175 Acquired absence of breast Neoplasms 1.01 0.937 – 1.08 0.815 797 7748 all phecode
180 Cervical cancer and dysplasia Neoplasms 1 0.939 – 1.07 0.888 940 8967 all phecode
180.1 Cervical cancer Neoplasms 1.02 0.931 – 1.13 0.619 461 4610 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.997 0.912 – 1.09 0.939 551 5388 all phecode
182 Malignant neoplasm of uterus Neoplasms 1 0.911 – 1.1 0.951 471 4691 all phecode
184 Cancer of other female genital organs Neoplasms 0.994 0.926 – 1.07 0.877 857 8412 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.03 0.948 – 1.13 0.442 548 5471 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1 0.913 – 1.1 0.932 473 4727 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.95 0.854 – 1.06 0.346 381 3805 all phecode
185 Cancer of prostate Neoplasms 0.934 0.886 – 0.985 0.0126 1794 7800 all phecode
187 Cancer of other male genital organs Neoplasms 0.955 0.882 – 1.03 0.251 685 6451 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.954 0.875 – 1.04 0.276 592 5545 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.948 0.87 – 1.03 0.222 597 5698 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.958 0.912 – 1.01 0.0898 1793 15041 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.935 0.869 – 1.01 0.0725 812 8117 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.929 0.861 – 1 0.0554 754 7538 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.937 0.794 – 1.1 0.436 156 1548 all phecode
189.2 Cancer of bladder Neoplasms 0.972 0.914 – 1.03 0.358 1147 10019 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.962 0.903 – 1.03 0.239 1058 9254 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.984 0.892 – 1.08 0.751 442 4279 all phecode
190 Cancer of eye Neoplasms 1.09 0.873 – 1.36 0.432 79 784 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.03 0.946 – 1.12 0.503 606 6032 all phecode
191.1 Cancer of brain and nervous system Neoplasms 1.02 0.922 – 1.14 0.657 400 4000 all phecode
191.11 Cancer of brain Neoplasms 1.01 0.897 – 1.13 0.902 324 3231 all phecode
193 Thyroid cancer Neoplasms 1.02 0.938 – 1.11 0.619 589 5872 all phecode
194 Cancer of other endocrine glands Neoplasms 0.982 0.828 – 1.16 0.836 160 1593 all phecode
195 Cancer, suspected or other Neoplasms 1.04 1.01 – 1.07 0.0228 4418 20000 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.04 0.999 – 1.08 0.0578 3448 18667 all phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1.06 0.975 – 1.15 0.175 629 6217 all phecode
196 Radiotherapy Neoplasms 0.993 0.936 – 1.05 0.824 1207 11404 all phecode
197 Chemotherapy Neoplasms 1.02 0.984 – 1.07 0.24 2690 19063 all phecode
198 Secondary malignant neoplasm Neoplasms 1.04 1 – 1.07 0.0445 3734 19920 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.04 0.999 – 1.09 0.0543 2389 18093 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1 0.927 – 1.09 0.929 680 6798 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.977 0.892 – 1.07 0.612 522 5213 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.14 1.03 – 1.25 0.0075 453 4509 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.919 0.824 – 1.02 0.124 387 3851 all phecode
198.6 Secondary malignancy of bone Neoplasms 0.991 0.902 – 1.09 0.858 481 4787 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.26 1.1 – 1.45 0.000848 210 2091 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.01 0.977 – 1.05 0.504 3670 20946 all phecode
199.4 Neurofibromatosis Neoplasms 0.923 0.693 – 1.22 0.571 58 580 all phecode
200 Myeloproliferative disease Neoplasms 1.02 0.943 – 1.11 0.584 651 6500 all phecode
200.1 Polycythemia vera Neoplasms 1.15 0.908 – 1.46 0.233 78 777 all phecode
201 Hodgkin's disease Neoplasms 0.975 0.793 – 1.19 0.809 100 994 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.03 0.964 – 1.1 0.4 1008 10059 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.05 0.983 – 1.12 0.145 937 9351 all phecode
202.21 Nodular lymphoma Neoplasms 1.03 0.953 – 1.12 0.412 616 6150 all phecode
202.24 Large cell lymphoma Neoplasms 0.916 0.721 – 1.16 0.466 79 782 all phecode
204 Leukemia Neoplasms 1.06 0.952 – 1.17 0.301 379 3786 all phecode
204.1 Lymphoid leukemia Neoplasms 1.01 0.848 – 1.19 0.941 138 1380 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.02 0.768 – 1.08 0.827 102 1012 all phecode
204.2 Myeloid leukemia Neoplasms 0.985 0.819 – 1.18 0.869 127 1270 all phecode
204.21 Myeloid leukemia, acute Neoplasms 1.05 0.86 – 1.28 0.614 100 1000 all phecode
204.4 Multiple myeloma Neoplasms 1.1 0.891 – 1.39 0.286 130 1271 all phecode
208 Benign neoplasm of colon Neoplasms 1 0.973 – 1.03 0.866 5516 24179 all phecode
209 Neuroendocrine tumors Neoplasms 0.905 0.747 – 1.09 0.3 124 1240 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.963 0.906 – 1.02 0.218 1162 11576 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.985 0.953 – 1.02 0.389 3981 24743 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.96 0.904 – 1.02 0.181 1191 11900 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.988 0.925 – 1.05 0.712 1007 9971 all phecode
214 Lipoma Neoplasms 0.938 0.868 – 1.01 0.099 759 7562 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.906 0.815 – 1.01 0.0631 403 4023 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.985 0.94 – 1.03 0.515 1969 19655 all phecode
216 Benign neoplasm of skin Neoplasms 1.09 1.06 – 1.12 1.81e-09 6667 23883 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.08 0.984 – 1.17 0.105 530 5254 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1.05 0.96 – 1.16 0.268 481 4772 all phecode
218 Benign neoplasm of uterus Neoplasms 0.981 0.94 – 1.02 0.38 2613 11674 all phecode
218.1 Uterine leiomyoma Neoplasms 1.04 0.973 – 1.11 0.251 979 9396 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.965 0.921 – 1.01 0.128 2183 11323 all phecode
220 Benign neoplasm of ovary Neoplasms 0.975 0.896 – 1.06 0.556 608 6015 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.02 0.959 – 1.09 0.52 1125 10048 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.944 0.869 – 1.02 0.165 648 6377 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.994 0.933 – 1.06 0.85 1120 8638 all phecode
224 Benign neoplasm of eye Neoplasms 1.12 1.01 – 1.24 0.0254 388 3858 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.13 1.01 – 1.26 0.0301 329 3255 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.04 0.959 – 1.12 0.366 741 7403 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.99 0.907 – 1.08 0.816 576 5754 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.15 0.988 – 1.34 0.0685 177 1770 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.963 0.894 – 1.04 0.319 787 7859 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.987 0.922 – 1.06 0.702 930 9289 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 0.944 0.828 – 1.08 0.389 249 2480 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.989 0.893 – 1.09 0.823 427 4222 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.11 0.98 – 1.26 0.0956 255 2543 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.01 0.947 – 1.09 0.684 902 9000 all phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 1.05 0.94 – 1.16 0.402 351 3510 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.05 1.02 – 1.08 0.00299 5138 25300 all phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 1.06 1.02 – 1.1 0.00152 3627 23859 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1 0.919 – 1.1 0.922 553 5508 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.97 0.918 – 1.02 0.278 1431 13548 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.977 0.92 – 1.04 0.457 1183 11806 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.961 0.886 – 1.04 0.337 664 6625 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.03 0.951 – 1.11 0.472 677 6736 all phecode
242.1 Graves' disease Endocrine/metabolic 1.01 0.891 – 1.15 0.837 248 2461 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.07 0.846 – 1.34 0.569 76 760 all phecode
242.3 Exophthalmos Endocrine/metabolic 0.975 0.805 – 1.18 0.79 126 1249 all phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.934 0.706 – 1.22 0.618 60 598 all phecode
244 Hypothyroidism Endocrine/metabolic 1.01 0.98 – 1.05 0.458 4513 22753 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.02 0.956 – 1.1 0.495 872 8700 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.01 0.908 – 1.12 0.845 378 3763 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.01 0.974 – 1.04 0.65 4206 22146 all phecode
245 Thyroiditis Endocrine/metabolic 1.09 0.972 – 1.21 0.141 346 3448 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.04 0.918 – 1.19 0.508 265 2627 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.03 0.904 – 1.17 0.654 260 2584 all phecode
246 Other disorders of thyroid Endocrine/metabolic 0.981 0.922 – 1.04 0.539 1116 10947 all phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1.11 0.973 – 1.25 0.12 251 2500 all phecode
249 Secondary diabetes mellitus Endocrine/metabolic 0.986 0.855 – 1.13 0.841 215 2144 all phecode
250 Diabetes mellitus Endocrine/metabolic 0.982 0.954 – 1.01 0.193 6571 23449 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.05 0.981 – 1.13 0.154 851 8507 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.14 1.05 – 1.2 0.206 59 582 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.13 0.973 – 1.3 0.105 183 1830 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.11 0.964 – 1.28 0.141 201 2010 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.02 0.863 – 1.21 0.799 157 1567 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.979 0.948 – 1.01 0.194 4744 22089 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.906 0.69 – 1.18 0.457 59 590 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.963 0.887 – 1.04 0.357 655 6536 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.05 0.952 – 1.15 0.337 459 4564 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1 0.939 – 1.07 0.948 1001 9978 all phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 0.955 0.796 – 1.14 0.602 140 1384 all phecode
250.3 Insulin pump user Endocrine/metabolic 1 0.939 – 1.07 0.962 1048 10475 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1 0.966 – 1.04 0.86 3031 21772 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.02 0.969 – 1.08 0.428 1534 15312 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1 0.96 – 1.05 0.833 2039 19010 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.02 0.935 – 1.1 0.71 621 6207 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.07 0.972 – 1.19 0.156 403 4019 all phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 0.965 0.716 – 1.28 0.798 57 570 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.01 0.906 – 1.11 0.924 395 3937 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1 0.944 – 1.07 0.906 1146 11426 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.01 0.946 – 1.07 0.793 1057 10545 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.866 0.727 – 1.03 0.102 159 1590 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.998 0.905 – 1.1 0.967 447 4455 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.08 0.892 – 1.3 0.423 111 1110 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.938 0.774 – 1.13 0.5 116 1160 all phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 0.978 0.763 – 1.25 0.857 74 731 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.869 0.65 – 1.15 0.327 58 580 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.95 0.884 – 1.02 0.163 833 8330 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.905 0.775 – 1.05 0.201 186 1860 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.912 0.727 – 1.14 0.417 91 910 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.876 0.666 – 1.14 0.324 65 641 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.895 0.792 – 1.01 0.0725 299 2973 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.857 0.753 – 0.974 0.0188 271 2691 all phecode
256 Ovarian dysfunction Endocrine/metabolic 0.922 0.833 – 1.02 0.111 443 4430 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.892 0.792 – 1 0.0544 326 3260 all phecode
257 Testicular dysfunction Endocrine/metabolic 0.944 0.859 – 1.04 0.226 511 5086 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.957 0.87 – 1.05 0.362 493 4908 all phecode
259 Other endocrine disorders Endocrine/metabolic 0.97 0.858 – 1.1 0.629 286 2858 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.03 0.977 – 1.09 0.247 1308 13039 all phecode
260.1 Cachexia Endocrine/metabolic 0.961 0.803 – 1.15 0.661 144 1436 all phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.09 1 – 1.18 0.0419 613 6108 all phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.03 0.853 – 1.25 0.737 114 1140 all phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.14 0.999 – 1.29 0.0491 255 2540 all phecode
260.6 Anorexia Endocrine/metabolic 0.961 0.863 – 1.07 0.475 389 3850 all phecode
261 Vitamin deficiency Endocrine/metabolic 0.988 0.953 – 1.02 0.503 3525 24019 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.993 0.89 – 1.11 0.899 358 3580 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.985 0.949 – 1.02 0.412 3313 23242 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.986 0.868 – 1.12 0.827 260 2590 all phecode
263 Other nutritional deficiency Endocrine/metabolic 0.956 0.872 – 1.05 0.334 529 5280 all phecode
264 Lack of normal physiological development Endocrine/metabolic 1 0.943 – 1.06 0.967 76 751 all phecode
269 Proteinuria Endocrine/metabolic 1.01 0.94 – 1.1 0.707 735 7213 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.06 0.96 – 1.18 0.235 398 3865 all phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.952 0.705 – 1.25 0.692 61 589 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.08 0.96 – 1.21 0.202 316 3032 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.07 0.933 – 1.24 0.314 210 1997 all phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.2 0.955 – 1.46 0.103 73 714 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.875 0.759 – 1.01 0.0638 223 2206 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.882 0.757 – 1.03 0.104 193 1909 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.986 0.961 – 1.01 0.274 10265 19513 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.986 0.961 – 1.01 0.266 10251 19507 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.984 0.945 – 1.02 0.419 3043 15630 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.931 0.848 – 1.02 0.131 519 5180 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.979 0.924 – 1.04 0.467 1332 12131 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.04 0.98 – 1.08 0.671 123 1213 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.01 0.948 – 1.07 0.821 1191 11876 all phecode
274.1 Gout Endocrine/metabolic 0.991 0.931 – 1.05 0.775 1107 11050 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.944 0.846 – 1.05 0.293 372 3715 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.13 0.93 – 1.37 0.208 115 1150 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.18 0.957 – 1.44 0.118 110 1099 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.953 0.908 – 1 0.0515 1865 18644 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.987 0.81 – 1.2 0.895 108 1080 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 0.904 0.82 – 0.995 0.0401 466 4651 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.957 0.901 – 1.02 0.155 1194 11909 all phecode
275.51 Hypocalcemia Endocrine/metabolic 0.925 0.817 – 1.05 0.217 273 2717 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.944 0.862 – 1.03 0.21 543 5427 all phecode
275.6 Hypercalcemia Endocrine/metabolic 1 0.91 – 1.1 0.975 457 4566 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.01 0.978 – 1.04 0.604 5107 25485 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 0.993 0.956 – 1.03 0.696 3192 22522 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.988 0.856 – 1.14 0.873 222 2203 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 0.972 0.915 – 1.03 0.357 1169 11544 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.02 0.965 – 1.08 0.497 1433 14011 all phecode
276.14 Hypopotassemia Endocrine/metabolic 0.993 0.93 – 1.06 0.834 962 9613 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 0.998 0.936 – 1.06 0.943 1035 10323 all phecode
276.41 Acidosis Endocrine/metabolic 0.981 0.915 – 1.05 0.596 881 8786 all phecode
276.42 Alkalosis Endocrine/metabolic 0.973 0.844 – 1.12 0.7 216 2160 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.01 0.973 – 1.06 0.517 2618 23255 all phecode
276.6 Fluid overload Endocrine/metabolic 1.01 0.938 – 1.1 0.72 711 7088 all phecode
276.8 Polydipsia Endocrine/metabolic 0.937 0.7 – 1.24 0.651 56 560 all phecode
277 Other disorders of metabolism Endocrine/metabolic 0.993 0.939 – 1.05 0.812 1380 13766 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.03 0.889 – 1.19 0.706 203 2027 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.98 0.896 – 1.07 0.649 554 5531 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.978 0.877 – 1.09 0.685 373 3726 all phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1.01 0.91 – 1.12 0.838 391 3910 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.977 0.955 – 1 0.0569 11126 19544 all phecode
278.1 Obesity Endocrine/metabolic 0.98 0.956 – 1 0.0923 10351 19542 all phecode
278.11 Morbid obesity Endocrine/metabolic 0.969 0.937 – 1 0.0668 4187 19492 all phecode
278.3 Localized adiposity Endocrine/metabolic 0.862 0.749 – 0.988 0.0339 235 2350 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.975 0.911 – 1.04 0.469 940 9274 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.01 0.952 – 1.07 0.733 1208 12073 all phecode
279.1 Immunity deficiency Endocrine/metabolic 0.985 0.891 – 1.09 0.766 433 4324 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.08 0.92 – 1.26 0.354 171 1700 all phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 0.834 0.654 – 1.06 0.131 71 710 all phecode
279.7 Other immunological findings Endocrine/metabolic 0.987 0.952 – 1.02 0.481 3389 25908 all phecode
280 Iron deficiency anemias Hematopoietic 1.01 0.963 – 1.05 0.813 2307 20801 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1 0.956 – 1.05 0.926 1978 19091 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.01 0.94 – 1.08 0.802 856 8545 all phecode
281 Other deficiency anemia Hematopoietic 0.99 0.861 – 1.14 0.887 224 2231 all phecode
281.1 Megaloblastic anemia Hematopoietic 0.915 0.743 – 1.12 0.389 108 1058 all phecode
281.11 Pernicious anemia Hematopoietic 0.965 0.646 – 0.997 0.788 53 530 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.893 0.647 – 1.18 0.396 56 551 all phecode
281.9 Deficiency anemias Hematopoietic 1 0.83 – 1.21 0.967 122 1199 all phecode
282 Hereditary hemolytic anemias Hematopoietic 0.93 0.765 – 1.13 0.46 122 1201 all phecode
282.8 Other hemoglobinopathies Hematopoietic 0.874 0.681 – 1.11 0.275 78 757 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.06 0.842 – 1.32 0.628 79 790 all phecode
284 Aplastic anemia Hematopoietic 1.08 0.959 – 1.21 0.199 299 2974 all phecode
284.1 Pancytopenia Hematopoietic 1.05 0.914 – 1.21 0.467 229 2272 all phecode
285 Other anemias Hematopoietic 0.998 0.969 – 1.03 0.884 5785 24163 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.995 0.946 – 1.05 0.843 1731 16445 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.05 0.978 – 1.12 0.186 910 9055 all phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.08 0.965 – 1.22 0.173 316 3151 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.02 0.908 – 1.15 0.71 300 2991 all phecode
286 Coagulation defects Hematopoietic 0.98 0.928 – 1.04 0.473 1453 14470 all phecode
286.1 Congenital coagulation defects Hematopoietic 0.894 0.744 – 1.07 0.223 133 1314 all phecode
286.11 Von willebrand's disease Hematopoietic 0.738 0.688 – 0.776 0.0258 51 502 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.06 0.82 – 1.36 0.659 65 634 all phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.03 0.977 – 1.08 0.293 1651 15048 all phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 0.938 0.759 – 1.15 0.543 101 1010 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.987 0.921 – 1.06 0.718 911 9092 all phecode
286.8 Hypercoagulable state Hematopoietic 0.98 0.878 – 1.09 0.708 381 3807 all phecode
286.81 Primary hypercoagulable state Hematopoietic 0.979 0.875 – 1.09 0.713 361 3606 all phecode
286.9 Abnormal coagulation profile Hematopoietic 0.997 0.893 – 1.11 0.961 363 3613 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.985 0.933 – 1.04 0.574 1488 14458 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.958 0.787 – 1.16 0.667 113 1127 all phecode
287.3 Thrombocytopenia Hematopoietic 0.974 0.921 – 1.03 0.363 1377 13471 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.04 0.874 – 1.24 0.635 149 1485 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.855 0.749 – 0.973 0.0182 261 2610 all phecode
288 Diseases of white blood cells Hematopoietic 1.02 0.97 – 1.06 0.509 2050 20073 all phecode
288.1 Decreased white blood cell count Hematopoietic 0.985 0.913 – 1.06 0.705 733 7302 all phecode
288.11 Neutropenia Hematopoietic 1.01 0.932 – 1.1 0.752 597 5935 all phecode
288.2 Elevated white blood cell count Hematopoietic 1.01 0.953 – 1.07 0.792 1366 13627 all phecode
288.3 Eosinophilia Hematopoietic 0.973 0.764 – 1.23 0.823 75 750 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.05 0.966 – 1.14 0.25 614 6102 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.05 0.92 – 1.2 0.449 230 2251 all phecode
289.4 Lymphadenitis Hematopoietic 0.984 0.943 – 1.03 0.439 2439 23341 all phecode
289.5 Diseases of spleen Hematopoietic 0.93 0.815 – 1.06 0.273 258 2580 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.17 0.929 – 1.48 0.173 79 790 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1 0.854 – 1.18 0.964 169 1686 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.06 0.973 – 1.15 0.186 624 5973 all phecode
290.1 Dementias Mental Disorders 1.01 0.889 – 1.16 0.827 231 2241 all phecode
290.11 Alzheimer's disease Mental Disorders 0.931 0.689 – 1.22 0.563 60 585 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.07 0.944 – 1.21 0.249 346 3405 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.997 0.905 – 1.1 0.955 456 4548 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.965 0.909 – 1.02 0.247 1207 12031 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.943 0.786 – 1.13 0.515 141 1410 all phecode
291.8 Alteration of consciousness Mental Disorders 0.968 0.908 – 1.03 0.322 1058 10555 all phecode
292 Neurological disorders Mental Disorders 1.01 0.97 – 1.05 0.645 2702 23616 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.975 0.911 – 1.04 0.475 923 9209 all phecode
292.11 Aphasia Mental Disorders 1.02 0.903 – 1.16 0.712 272 2719 all phecode
292.12 Symbolic dysfunction Mental Disorders 0.951 0.777 – 1.16 0.618 110 1100 all phecode
292.2 Mild cognitive impairment Mental Disorders 1.01 0.931 – 1.05 0.886 107 1047 all phecode
292.3 Memory loss Mental Disorders 1.03 0.954 – 1.1 0.48 793 7884 all phecode
292.4 Altered mental status Mental Disorders 1.02 0.958 – 1.08 0.547 1108 11009 all phecode
292.5 Transient alteration of awareness Mental Disorders 0.789 0.632 – 0.979 0.0318 98 951 all phecode
292.6 Hallucinations Mental Disorders 1.13 0.907 – 1.41 0.259 86 851 all phecode
293 Symptoms involving head and neck Mental Disorders 0.917 0.769 – 1.09 0.327 140 1397 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.973 0.935 – 1.01 0.17 2758 25622 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.07 0.96 – 1.19 0.221 380 2493 all phecode
295.1 Schizophrenia Mental Disorders 1.03 0.805 – 1.33 0.787 78 483 all phecode
295.3 Psychosis Mental Disorders 1.09 0.962 – 1.23 0.177 290 1913 all phecode
296 Mood disorders Mental Disorders 0.998 0.97 – 1.03 0.876 7043 19850 all phecode
296.1 Bipolar Mental Disorders 0.962 0.896 – 1.03 0.29 886 5627 all phecode
296.2 Depression Mental Disorders 0.999 0.972 – 1.03 0.972 6651 19846 all phecode
296.22 Major depressive disorder Mental Disorders 1.03 0.975 – 1.08 0.31 1586 10368 all phecode
297 Suicidal ideation or attempt Mental Disorders 0.957 0.779 – 0.995 0.402 380 2480 all phecode
297.1 Suicidal ideation Mental Disorders 0.973 0.72 – 1.01 0.632 313 2013 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.864 0.711 – 1.04 0.132 122 772 all phecode
300 Anxiety disorders Mental Disorders 0.988 0.961 – 1.02 0.42 6782 19893 all phecode
300.1 Anxiety disorder Mental Disorders 0.99 0.961 – 1.02 0.474 6337 19891 all phecode
300.11 Generalized anxiety disorder Mental Disorders 0.975 0.914 – 1.04 0.43 1096 7023 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.06 0.967 – 1.15 0.221 566 3553 all phecode
300.13 Phobia Mental Disorders 1.13 0.947 – 1.34 0.173 141 907 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.947 0.882 – 1 0.565 113 689 all phecode
300.4 Dysthymic disorder Mental Disorders 0.973 0.906 – 1.04 0.439 914 5746 all phecode
300.8 Acute reaction to stress Mental Disorders 0.986 0.86 – 1.13 0.832 242 1461 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.981 0.872 – 1.1 0.746 326 2014 all phecode
301 Personality disorders Mental Disorders 1.06 0.732 – 1.1 0.326 209 1257 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1 0.797 – 1.05 0.958 140 838 all phecode
302 Sexual and gender identity disorders Mental Disorders 1 0.897 – 1.12 0.982 377 2508 all phecode
302.1 Decreased libido Mental Disorders 1.08 0.915 – 1.28 0.35 152 961 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.01 0.914 – 1.11 0.909 505 3183 all phecode
303.3 Psychogenic disorder Mental Disorders 0.987 0.865 – 1.13 0.847 267 1630 all phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 1.01 0.834 – 1.22 0.922 131 825 all phecode
303.4 Somatoform disorder Mental Disorders 1.03 0.906 – 1.17 0.641 262 1602 all phecode
304 Adjustment reaction Mental Disorders 0.972 0.924 – 1.02 0.256 1826 12239 all phecode
305.2 Eating disorder Mental Disorders 0.897 0.785 – 1.02 0.108 268 1623 all phecode
306 Other mental disorder Mental Disorders 1.02 0.921 – 1.13 0.723 432 2687 all phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 0.973 0.808 – 1.16 0.713 202 1163 all phecode
306.9 Tension headache Mental Disorders 0.988 0.827 – 1.18 0.894 144 869 all phecode
312 Conduct disorders Mental Disorders 0.888 0.691 – 1.1 0.264 88 872 all phecode
313 Pervasive developmental disorders Mental Disorders 1 0.917 – 1.1 0.936 534 5301 all phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1.04 0.94 – 1.14 0.47 446 4428 all phecode
315 Develomental delays and disorders Mental Disorders 1.02 0.88 – 1.19 0.767 219 2183 all phecode
316 Substance addiction and disorders Mental Disorders 1.02 0.964 – 1.07 0.533 1510 15048 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.09 0.972 – 1.22 0.138 332 3306 all phecode
317 Alcohol-related disorders Mental Disorders 1.03 0.967 – 1.09 0.374 1226 12156 all phecode
317.1 Alcoholism Mental Disorders 1.05 0.978 – 1.12 0.183 880 8722 all phecode
317.11 Alcoholic liver damage Mental Disorders 0.997 0.874 – 1.14 0.966 246 2450 all phecode
318 Tobacco use disorder Mental Disorders 0.981 0.954 – 1.01 0.162 7065 22379 all phecode
320 Meningitis Neurological 1.02 0.867 – 1.19 0.838 169 1690 all phecode
323 Encephalitis Neurological 0.858 0.68 – 1.07 0.181 87 870 all phecode
323.8 Encephalitis, non-infectious Neurological 0.812 0.624 – 1.05 0.111 69 690 all phecode
324 Other CNS infection and poliomyelitis Neurological 0.956 0.793 – 1.14 0.605 147 1460 all phecode
327 Sleep disorders Neurological 0.997 0.968 – 1.03 0.813 6050 23068 all phecode
327.1 Hypersomnia Neurological 0.947 0.85 – 1.05 0.324 378 3756 all phecode
327.3 Sleep apnea Neurological 0.988 0.959 – 1.02 0.443 5492 22522 all phecode
327.31 Central/nonobstroctive sleep apnea Neurological 1.08 0.852 – 1.37 0.507 70 700 all phecode
327.32 Obstructive sleep apnea Neurological 1.01 0.971 – 1.04 0.707 3525 21245 all phecode
327.4 Insomnia Neurological 1.02 0.976 – 1.06 0.455 2779 22130 all phecode
327.41 Organic or persistent insomnia Neurological 1.01 0.944 – 1.08 0.736 900 8999 all phecode
327.5 Parasomnia Neurological 1.02 0.905 – 1.15 0.754 296 2958 all phecode
327.6 Circadian rhythm sleep disorder Neurological 1.03 0.838 – 1.26 0.794 104 1033 all phecode
327.7 Sleep related movement disorders Neurological 1.03 0.946 – 1.11 0.524 629 6290 all phecode
327.71 Restless legs syndrome Neurological 1.04 0.959 – 1.14 0.309 573 5730 all phecode
331 Other cerebral degenerations Neurological 0.913 0.837 – 0.996 0.0416 573 5621 all phecode
331.1 Hydrocephalus Neurological 0.901 0.771 – 1.05 0.18 176 1750 all phecode
331.9 Cerebral degeneration, unspecified Neurological 0.879 0.78 – 0.989 0.0324 318 3071 all phecode
332 Parkinson's disease Neurological 0.97 0.848 – 1.11 0.654 234 2320 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.02 0.96 – 1.09 0.491 1052 10510 all phecode
333.1 Essential tremor Neurological 0.945 0.844 – 1.06 0.32 360 3596 all phecode
333.2 Myoclonus Neurological 1.03 0.949 – 1.08 0.794 67 660 all phecode
333.4 Torsion dystonia Neurological 1.07 0.913 – 1.25 0.398 161 1610 all phecode
334 Degenerative disease of the spinal cord Neurological 0.915 0.836 – 1 0.0517 541 5404 all phecode
334.2 Anterior horn cell disease Neurological 0.998 0.769 – 1.29 0.986 65 650 all phecode
335 Multiple sclerosis Neurological 0.913 0.796 – 1.04 0.187 234 2340 all phecode
337 Disorders of the autonomic nervous system Neurological 0.994 0.868 – 1.14 0.935 227 2270 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.01 0.784 – 1.26 0.945 94 921 all phecode
338 Pain Neurological 0.978 0.951 – 1.01 0.123 6219 24423 all phecode
338.1 Acute pain Neurological 0.972 0.941 – 1 0.0879 4436 24130 all phecode
338.2 Chronic pain Neurological 0.981 0.942 – 1.02 0.373 2538 21419 all phecode
339 Other headache syndromes Neurological 0.982 0.95 – 1.01 0.279 4406 24884 all phecode
340 Migraine Neurological 0.956 0.915 – 0.999 0.0463 2362 16920 all phecode
340.1 Migrain with aura Neurological 0.979 0.898 – 1.07 0.633 573 5700 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.986 0.756 – 1.27 0.913 63 630 all phecode
342 Hemiplegia Neurological 0.931 0.81 – 1.07 0.307 235 2349 all phecode
343 Infantile cerebral palsy Neurological 1 0.921 – 1.05 0.978 54 534 all phecode
344 Other paralytic syndromes Neurological 1 0.899 – 1.12 0.935 352 3520 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.987 0.927 – 1.05 0.666 1102 11005 all phecode
345.1 Epilepsy Neurological 0.916 0.823 – 1.02 0.102 382 3812 all phecode
345.11 Generalized convulsive epilepsy Neurological 0.844 0.683 – 1.04 0.109 99 990 all phecode
345.12 Partial epilepsy Neurological 0.93 0.817 – 1.06 0.262 257 2565 all phecode
345.3 Convulsions Neurological 0.987 0.92 – 1.06 0.71 876 8735 all phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 1.25 0.962 – 1.61 0.0887 67 660 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.02 0.953 – 1.1 0.537 873 8722 all phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 0.848 0.664 – 1.08 0.173 75 741 all phecode
348 Other conditions of brain Neurological 0.972 0.91 – 1.04 0.393 1013 10105 all phecode
348.2 Cerebral edema and compression of brain Neurological 0.968 0.882 – 1.06 0.485 505 5050 all phecode
348.4 Cerebral cysts Neurological 0.996 0.839 – 1.18 0.964 147 1463 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 0.959 0.869 – 1.06 0.402 456 4553 all phecode
348.9 Other conditions of brain, NOS Neurological 1 0.952 – 1.06 0.905 1552 15496 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.953 0.869 – 1.04 0.301 520 5191 all phecode
350 Abnormal movement Neurological 1 0.965 – 1.04 0.884 2950 25091 all phecode
350.1 Abnormal involuntary movements Neurological 1.01 0.954 – 1.06 0.781 1427 14243 all phecode
350.2 Abnormality of gait Neurological 0.978 0.93 – 1.03 0.395 1707 16093 all phecode
350.3 Lack of coordination Neurological 0.963 0.859 – 1.08 0.506 330 3300 all phecode
350.5 Abnormal reflex Neurological 0.959 0.722 – 1.26 0.76 58 573 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.946 0.817 – 1.09 0.446 207 2060 all phecode
351 Other peripheral nerve disorders Neurological 0.992 0.958 – 1.03 0.674 3518 25379 all phecode
352 Disorders of other cranial nerves Neurological 1.05 0.978 – 1.12 0.183 901 9006 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.949 0.836 – 1.07 0.407 282 2816 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.05 0.948 – 1.16 0.342 423 4227 all phecode
353 Nerve root and plexus disorders Neurological 0.968 0.866 – 1.08 0.563 355 3531 all phecode
353.1 Nerve plexus lesions Neurological 0.954 0.814 – 1.11 0.55 179 1790 all phecode
355 Complex regional/central pain syndrome Neurological 1.12 0.977 – 1.29 0.0989 226 2260 all phecode
355.1 Chronic pain syndrome Neurological 1.01 0.864 – 1.19 0.868 165 1650 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.995 0.936 – 1.06 0.863 1175 11652 all phecode
357 Inflammatory and toxic neuropathy Neurological 0.973 0.908 – 1.04 0.427 906 9030 all phecode
358 Myoneural disorders Neurological 0.929 0.753 – 1.14 0.484 101 1007 all phecode
358.1 Myasthenia gravis Neurological 1.05 0.96 – 1.09 0.688 57 564 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.96 0.852 – 1.08 0.494 306 3043 all phecode
359.2 Myopathy Neurological 0.962 0.851 – 1.09 0.535 283 2813 all phecode
360 Disorders of the globe Sense Organs 1.02 0.798 – 1.29 0.882 78 771 all phecode
361 Retinal detachments and defects Sense Organs 1.07 0.953 – 1.21 0.235 291 2908 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.19 1 – 1.43 0.0499 132 1307 all phecode
362 Other retinal disorders Sense Organs 0.987 0.936 – 1.04 0.643 1506 13094 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.972 0.907 – 1.04 0.41 910 8102 all phecode
362.21 Macular degeneration, dry Sense Organs 0.984 0.908 – 1.02 0.76 214 1906 all phecode
362.22 Macular degeneration, wet Sense Organs 0.885 0.792 – 0.924 0.233 77 638 all phecode
362.23 Cystoid macular degeneration of retina Sense Organs 0.893 0.743 – 1.07 0.217 141 1390 all phecode
362.26 Macular puckering of retina Sense Organs 0.938 0.826 – 1.06 0.258 340 3337 all phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.859 0.743 – 0.99 0.0364 213 2089 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.969 0.744 – 1.01 0.535 362 3218 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.941 0.832 – 1.06 0.332 283 2806 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.01 0.9 – 1.14 0.819 293 2899 all phecode
362.6 Peripheral retinal degenerations Sense Organs 0.973 0.824 – 1.15 0.744 155 1541 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.741 0.555 – 0.982 0.0366 63 626 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1 0.764 – 1.05 0.971 100 996 all phecode
362.9 Retinal edema Sense Organs 0.876 0.668 – 1.09 0.146 121 1201 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.03 0.894 – 1.18 0.687 219 2166 all phecode
363.3 Chorioretinal scars Sense Organs 1.12 0.943 – 1.32 0.195 154 1524 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.974 0.891 – 1.06 0.551 538 5323 all phecode
364.1 Corneal opacity Sense Organs 0.904 0.779 – 1.05 0.178 202 2013 all phecode
364.2 Corneal edema Sense Organs 0.712 0.515 – 0.967 0.031 52 515 all phecode
364.4 Corneal degenerations Sense Organs 0.893 0.754 – 1.05 0.183 161 1600 all phecode
364.5 Corneal dystrophy Sense Organs 0.999 0.885 – 1.13 0.993 284 2796 all phecode
364.51 Fuchs' dystrophy Sense Organs 1.04 0.788 – 1.09 0.601 131 1300 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.932 0.701 – 1.22 0.607 55 541 all phecode
365 Glaucoma Sense Organs 1 0.943 – 1.07 0.919 1106 10654 all phecode
365.1 Open-angle glaucoma Sense Organs 1.02 0.906 – 1.16 0.657 342 3328 all phecode
365.11 Primary open angle glaucoma Sense Organs 0.937 0.872 – 0.973 0.319 207 2006 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.1 0.907 – 1.34 0.316 109 1055 all phecode
366 Cataract Sense Organs 1.01 0.97 – 1.04 0.779 3689 19186 all phecode
366.1 Nonsenile Cataract Sense Organs 1.03 0.787 – 1.07 0.743 135 1332 all phecode
366.2 Senile cataract Sense Organs 0.999 0.958 – 1.04 0.954 2616 16782 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.979 0.949 – 1.01 0.197 4681 25934 all phecode
367.1 Myopia Sense Organs 0.987 0.949 – 1.03 0.532 2752 22991 all phecode
367.2 Astigmatism Sense Organs 0.998 0.947 – 1.05 0.949 1527 15060 all phecode
367.4 Presbyopia Sense Organs 0.997 0.954 – 1.04 0.901 2222 19016 all phecode
367.8 Hypermetropia Sense Organs 0.951 0.894 – 1.01 0.105 1149 11387 all phecode
367.9 Blindness and low vision Sense Organs 0.988 0.89 – 1.1 0.821 400 3992 all phecode
368 Visual disturbances Sense Organs 1 0.958 – 1.04 0.985 2272 22272 all phecode
368.1 Amblyopia Sense Organs 0.992 0.841 – 1.17 0.928 152 1504 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.967 0.885 – 1.06 0.45 562 5610 all phecode
368.3 Anisometropia Sense Organs 0.929 0.769 – 1.12 0.439 124 1222 all phecode
368.4 Visual field defects Sense Organs 1.01 0.919 – 1.11 0.789 532 5315 all phecode
368.9 Subjective visual disturbances Sense Organs 0.962 0.882 – 1.05 0.379 573 5704 all phecode
369 Infection of the eye Sense Organs 0.998 0.947 – 1.05 0.946 1559 15432 all phecode
369.2 Eye infection, viral Sense Organs 0.918 0.797 – 1.06 0.235 227 2240 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.984 0.93 – 1.04 0.581 1317 13136 all phecode
370 Keratitis Sense Organs 0.976 0.902 – 1.05 0.539 711 6972 all phecode
370.1 Corneal ulcer Sense Organs 1.07 0.857 – 1.34 0.529 90 890 all phecode
370.2 Superficial keratitis Sense Organs 0.992 0.87 – 1.13 0.902 249 2474 all phecode
370.3 Keratoconjunctivitis Sense Organs 0.95 0.854 – 1.06 0.341 387 3780 all phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.921 0.708 – 1.15 0.369 124 1194 all phecode
371 Inflammation of the eye Sense Organs 1.01 0.967 – 1.06 0.606 2106 18893 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.861 0.759 – 0.975 0.0186 292 2902 all phecode
371.2 Conjunctivitis, noninfectious Sense Organs 1.14 1.03 – 1.26 0.0136 392 3893 all phecode
371.21 Allergic conjunctivitis Sense Organs 1.14 1.01 – 1.28 0.0273 293 2898 all phecode
371.3 Inflammation of eyelids Sense Organs 1.02 0.968 – 1.07 0.464 1606 15153 all phecode
372 Disorders of conjunctiva Sense Organs 1.03 0.941 – 1.13 0.525 523 5153 all phecode
374 Other disorders of eyelids Sense Organs 1.05 0.991 – 1.11 0.0978 1302 12613 all phecode
374.1 Ectropion or entropion Sense Organs 1.07 0.925 – 1.24 0.353 194 1910 all phecode
374.2 Lagophthalmos Sense Organs 1 0.828 – 1.21 0.968 123 1229 all phecode
374.3 Ptosis of eyelid Sense Organs 0.983 0.897 – 1.08 0.713 504 5016 all phecode
374.6 Dermatochalasis Sense Organs 1.01 0.923 – 1.11 0.764 469 4650 all phecode
375 Disorders of lacrimal system Sense Organs 0.959 0.836 – 1.1 0.551 235 2341 all phecode
375.1 Dry eyes Sense Organs 0.98 0.932 – 1.03 0.433 1711 14550 all phecode
375.2 Epiphora Sense Organs 0.948 0.816 – 1.1 0.483 200 1999 all phecode
376 Disorders of the orbit Sense Organs 1.09 1.01 – 1.12 0.356 102 1020 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.938 0.844 – 1.04 0.232 400 3948 all phecode
377.1 Optic atrophy Sense Organs 0.89 0.848 – 0.938 0.19 117 1170 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.868 0.754 – 0.998 0.0478 230 2283 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.94 0.868 – 1.02 0.127 694 6883 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.926 0.838 – 1.02 0.125 442 4389 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.993 0.801 – 1.23 0.951 100 987 all phecode
378.5 Paralytic strabismus Sense Organs 1.05 0.909 – 1.21 0.494 207 2060 all phecode
379 Other disorders of eye Sense Organs 0.996 0.951 – 1.04 0.868 2085 17093 all phecode
379.1 Scleritis and episcleritis Sense Organs 1.09 0.881 – 1.33 0.43 90 894 all phecode
379.2 Disorders of vitreous body Sense Organs 0.994 0.942 – 1.05 0.827 1519 12947 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.825 0.654 – 1.03 0.0929 86 846 all phecode
379.4 Anomalies of pupillary function Sense Organs 0.952 0.803 – 1.12 0.563 152 1515 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.03 0.861 – 1.23 0.741 129 1281 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.943 0.862 – 1.03 0.194 556 5528 all phecode
380 Disorders of external ear Sense Organs 1.06 0.897 – 1.25 0.483 151 1508 all phecode
380.1 Otitis externa Sense Organs 0.939 0.87 – 1.01 0.104 741 7380 all phecode
380.4 Impacted cerumen Sense Organs 0.968 0.917 – 1.02 0.229 1499 14330 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.992 0.948 – 1.04 0.724 2133 20765 all phecode
381.1 Otitis media Sense Organs 0.994 0.942 – 1.05 0.837 1476 14637 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.976 0.92 – 1.04 0.421 1250 12480 all phecode
381.2 Eustachian tube disorders Sense Organs 0.99 0.926 – 1.06 0.763 971 9677 all phecode
381.3 Mastoiditis & related conditions Sense Organs 0.799 0.606 – 1.04 0.0981 64 640 all phecode
381.9 Otorrhea Sense Organs 1.14 0.966 – 1.34 0.117 159 1574 all phecode
382 Otalgia Sense Organs 1 0.933 – 1.07 0.99 903 9000 all phecode
383 Otosclerosis Sense Organs 0.913 0.728 – 1.14 0.423 89 890 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.08 0.937 – 1.23 0.296 221 2203 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.09 0.943 – 1.26 0.234 187 1856 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.968 0.846 – 1.11 0.63 235 2350 all phecode
385.3 Cholesteatoma Sense Organs 0.921 0.784 – 1.08 0.312 176 1760 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.04 0.813 – 1.31 0.763 71 710 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.02 0.953 – 1.09 0.57 915 9099 all phecode
386.1 Meniere's disease Sense Organs 1.06 0.778 – 1.11 0.515 119 1171 all phecode
386.2 Peripheral or central vertigo Sense Organs 0.993 0.918 – 1.07 0.859 694 6896 all phecode
386.3 Labyrinthitis Sense Organs 1.12 0.961 – 1.3 0.142 171 1694 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1 0.969 – 1.04 0.829 3609 25786 all phecode
388 Other disorders of ear Sense Organs 1.01 0.897 – 1.13 0.874 315 3140 all phecode
389 Hearing loss Sense Organs 1 0.967 – 1.04 0.936 3708 25750 all phecode
389.1 Sensorineural hearing loss Sense Organs 1.02 0.974 – 1.06 0.435 2178 19347 all phecode
389.2 Conductive hearing loss Sense Organs 0.992 0.905 – 1.09 0.867 515 5142 all phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.966 0.737 – 1.25 0.788 69 680 all phecode
389.4 Tinnitus Sense Organs 1.06 0.99 – 1.14 0.0911 889 8870 all phecode
394 Rheumatic disease of the heart valves Circulatory System 0.994 0.937 – 1.05 0.847 1216 11503 all phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 0.948 0.821 – 1.09 0.457 216 2134 all phecode
394.2 Mitral valve disease Circulatory System 0.979 0.896 – 1.07 0.628 556 5510 all phecode
394.3 Aortic valve disease Circulatory System 0.984 0.888 – 1.09 0.758 413 3996 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.05 0.943 – 1.18 0.352 328 3256 all phecode
395 Heart valve disorders Circulatory System 0.985 0.94 – 1.03 0.536 1981 17661 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.966 0.908 – 1.03 0.28 1107 10905 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.999 0.934 – 1.07 0.978 945 9002 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 0.922 0.809 – 1.05 0.215 256 2540 all phecode
395.6 Heart valve replaced Circulatory System 0.98 0.902 – 1.06 0.632 629 6079 all phecode
396 Abnormal heart sounds Circulatory System 1.02 0.96 – 1.08 0.539 1215 12054 all phecode
401 Hypertension Circulatory System 0.978 0.953 – 1 0.0781 13126 17239 all phecode
401.1 Essential hypertension Circulatory System 0.976 0.952 – 1 0.0593 12947 17239 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1 0.951 – 1.06 0.937 1700 10273 all phecode
401.21 Hypertensive heart disease Circulatory System 1.01 0.857 – 1.19 0.881 158 1524 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.01 0.955 – 1.07 0.75 1535 9797 all phecode
401.3 Other hypertensive complications Circulatory System 0.981 0.922 – 1.04 0.548 1148 9924 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 0.994 0.939 – 1.05 0.846 1331 12405 all phecode
411 Ischemic Heart Disease Circulatory System 0.976 0.945 – 1.01 0.148 4915 20312 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.957 0.868 – 1.05 0.375 450 4414 all phecode
411.2 Myocardial infarction Circulatory System 1.01 0.96 – 1.06 0.713 1702 12837 all phecode
411.3 Angina pectoris Circulatory System 0.966 0.894 – 1.04 0.369 737 7089 all phecode
411.4 Coronary atherosclerosis Circulatory System 0.97 0.938 – 1 0.0862 4396 19028 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1 0.864 – 1.16 0.963 197 1953 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.02 0.944 – 1.09 0.685 823 7474 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.03 0.906 – 1.17 0.637 244 2387 all phecode
414 Other forms of chronic heart disease Circulatory System 1.01 0.947 – 1.07 0.835 1152 10966 all phecode
414.2 ASCVD Circulatory System 1.09 0.947 – 1.25 0.229 217 2132 all phecode
415 Pulmonary heart disease Circulatory System 0.996 0.947 – 1.05 0.872 1683 16616 all phecode
415.1 Acute pulmonary heart disease Circulatory System 1.04 0.963 – 1.12 0.323 712 7112 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.04 0.964 – 1.12 0.305 708 7070 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1 0.932 – 1.07 0.995 884 8815 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1 0.894 – 1.12 0.999 342 3403 all phecode
416 Cardiomegaly Circulatory System 0.941 0.864 – 1.03 0.167 593 5897 all phecode
418 Nonspecific chest pain Circulatory System 0.996 0.969 – 1.02 0.745 7097 23491 all phecode
418.1 Precordial pain Circulatory System 1.02 0.951 – 1.08 0.646 987 9853 all phecode
420 Carditis Circulatory System 0.941 0.872 – 1.02 0.12 754 7518 all phecode
420.2 Pericarditis Circulatory System 0.934 0.847 – 1.03 0.163 481 4804 all phecode
420.21 Acute pericarditis Circulatory System 0.896 0.794 – 0.931 0.292 87 861 all phecode
420.22 Chronic pericarditis Circulatory System 1.06 0.806 – 1.38 0.68 62 620 all phecode
420.3 Endocarditis Circulatory System 0.995 0.876 – 1.13 0.939 267 2650 all phecode
425 Cardiomyopathy Circulatory System 1.04 0.981 – 1.11 0.171 1096 10739 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.04 0.972 – 1.1 0.281 1066 10448 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.1 0.914 – 1.32 0.305 128 1266 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.936 0.748 – 1.17 0.552 90 900 all phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.14 0.943 – 1.38 0.172 124 1237 all phecode
426 Cardiac conduction disorders Circulatory System 0.996 0.968 – 1.03 0.801 7210 17839 all phecode
426.2 Atrioventricular [AV] block Circulatory System 0.986 0.925 – 1.05 0.653 1143 7891 all phecode
426.21 First degree AV block Circulatory System 0.959 0.891 – 1.03 0.264 832 6368 all phecode
426.23 Second degree AV block Circulatory System 1.01 0.75 – 1.06 0.917 97 898 all phecode
426.24 Atrioventricular block, complete Circulatory System 0.996 0.871 – 1.14 0.947 242 2120 all phecode
426.25 Other heart block Circulatory System 1.03 0.807 – 1.1 0.727 121 1098 all phecode
426.3 Bundle branch block Circulatory System 1.01 0.95 – 1.07 0.769 1226 9124 all phecode
426.31 Right bundle branch block Circulatory System 1.01 0.938 – 1.09 0.788 812 7016 all phecode
426.32 Left bundle branch block Circulatory System 0.996 0.902 – 1.1 0.933 438 4157 all phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 0.994 0.964 – 1.02 0.707 6081 17672 all phecode
426.8 Other cardiac conduction disorders Circulatory System 0.931 0.799 – 1.08 0.357 192 1913 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1 0.93 – 1.08 0.92 745 6035 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.984 0.899 – 1.08 0.73 533 4363 all phecode
426.92 Cardiac defibrillator in situ Circulatory System 1 0.893 – 1.12 0.975 331 3178 all phecode
427 Cardiac dysrhythmias Circulatory System 1 0.979 – 1.03 0.761 10192 18017 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1 0.938 – 1.07 0.974 1046 9517 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.01 0.925 – 1.1 0.847 585 5772 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.975 0.843 – 1.12 0.57 543 5165 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.01 0.97 – 1.05 0.598 2919 12586 all phecode
427.21 Atrial fibrillation Circulatory System 0.998 0.952 – 1.05 0.941 2217 11443 all phecode
427.22 Atrial flutter Circulatory System 1.06 0.971 – 1.15 0.194 587 5395 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.995 0.964 – 1.03 0.751 5582 18019 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.998 0.876 – 1.14 0.976 261 2559 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.864 0.69 – 1.07 0.184 97 969 all phecode
427.42 Cardiac arrest Circulatory System 0.999 0.861 – 1.16 0.985 203 2000 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.993 0.954 – 1.03 0.732 2897 17415 all phecode
427.6 Premature beats Circulatory System 1 0.944 – 1.07 0.885 1161 9505 all phecode
427.61 Supraventricular premature beats Circulatory System 1.01 0.903 – 1.12 0.908 357 3397 all phecode
427.7 Tachycardia NOS Circulatory System 1.03 0.985 – 1.07 0.227 2772 17929 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1 0.92 – 1.09 0.926 565 5082 all phecode
427.9 Palpitations Circulatory System 0.993 0.952 – 1.04 0.752 2480 16718 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.02 0.969 – 1.06 0.531 2011 15882 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.03 0.974 – 1.08 0.317 1548 13804 all phecode
428.2 Heart failure NOS Circulatory System 1.03 0.966 – 1.1 0.36 1033 9643 all phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.1 1 – 1.21 0.0457 477 4733 all phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.05 0.948 – 1.16 0.352 418 4122 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1 0.97 – 1.04 0.785 3650 22491 all phecode
429.1 Heart transplant/surgery Circulatory System 1 0.904 – 1.11 0.957 421 4183 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.981 0.937 – 1.03 0.4 2116 17256 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.05 0.998 – 1.1 0.0597 1836 16273 all phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 0.855 0.757 – 0.965 0.0114 311 3074 all phecode
430 Intracranial hemorrhage Circulatory System 1 0.906 – 1.11 0.947 423 4215 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.995 0.85 – 1.16 0.948 181 1808 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1.04 0.909 – 1.2 0.538 223 2215 all phecode
430.3 Subdural hemorrhage Circulatory System 1.07 0.88 – 1.29 0.499 122 1211 all phecode
433 Cerebrovascular disease Circulatory System 0.992 0.954 – 1.03 0.709 2858 20352 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.02 0.956 – 1.09 0.555 1049 9556 all phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.14 0.933 – 1.39 0.191 103 1024 all phecode
433.12 Cerebral atherosclerosis Circulatory System 0.984 0.734 – 1.31 0.91 52 511 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.993 0.92 – 1.07 0.85 727 7183 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1 0.921 – 1.09 0.945 579 5745 all phecode
433.3 Cerebral ischemia Circulatory System 1.02 0.964 – 1.08 0.504 1366 12552 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.01 0.954 – 1.08 0.64 1127 10698 all phecode
433.5 Cerebral aneurysm Circulatory System 0.94 0.78 – 1.11 0.287 310 3081 all phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.09 0.978 – 1.21 0.116 346 3448 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.08 0.961 – 1.21 0.198 329 3275 all phecode
440 Atherosclerosis Circulatory System 0.987 0.935 – 1.04 0.625 1493 13489 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.21 1.01 – 1.53 0.0274 125 1240 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.02 0.947 – 1.09 0.642 862 8502 all phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 0.984 0.926 – 1.02 0.843 107 1056 all phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1 0.921 – 1.09 0.985 626 6223 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.03 0.944 – 1.12 0.527 574 5624 all phecode
441 Vascular insufficiency of intestine Circulatory System 0.94 0.829 – 1.06 0.329 282 2798 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.04 0.881 – 1.23 0.613 148 1470 all phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 0.923 0.732 – 1.15 0.479 92 902 all phecode
442 Other aneurysm Circulatory System 1.02 0.967 – 1.07 0.508 1637 13881 all phecode
442.1 Aortic aneurysm Circulatory System 1.02 0.963 – 1.08 0.471 1234 10807 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.02 0.943 – 1.1 0.62 682 6454 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.08 0.898 – 1.29 0.42 137 1369 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.07 0.88 – 1.3 0.496 117 1161 all phecode
442.4 Arterial dissection Circulatory System 1.05 0.851 – 1.28 0.658 98 980 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.09 0.959 – 1.24 0.182 252 2513 all phecode
443 Peripheral vascular disease Circulatory System 0.966 0.916 – 1.02 0.195 1561 14577 all phecode
443.1 Raynaud's syndrome Circulatory System 1.01 0.9 – 1.13 0.893 347 3470 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.953 0.826 – 1.1 0.507 220 2176 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.03 0.851 – 1.24 0.77 124 1234 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.963 0.905 – 1.02 0.229 1120 10522 all phecode
444 Arterial embolism and thrombosis Circulatory System 0.981 0.891 – 1.08 0.693 458 4530 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.02 0.868 – 1.19 0.812 165 1635 all phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 1.18 0.954 – 1.47 0.118 86 851 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 0.996 0.872 – 1.13 0.952 248 2464 all phecode
446.4 Wegener's granulomatosis Circulatory System 0.853 0.638 – 1.13 0.264 59 582 all phecode
446.9 Arteritis NOS Circulatory System 0.978 0.824 – 1.15 0.79 151 1506 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.03 0.964 – 1.09 0.412 1074 10638 all phecode
447.1 Stricture of artery Circulatory System 1.03 0.918 – 1.17 0.573 301 2968 all phecode
447.7 Aortic ectasia Circulatory System 0.977 0.856 – 1.11 0.733 246 2452 all phecode
448 Disease of capillaries Circulatory System 1.03 0.73 – 1.07 0.772 103 1023 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.06 0.995 – 1.13 0.071 1088 10867 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.08 0.956 – 1.22 0.165 365 3617 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.11 0.911 – 1.37 0.253 120 1198 all phecode
452 Other venous embolism and thrombosis Circulatory System 0.99 0.945 – 1.04 0.677 2038 17308 all phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1.07 0.872 – 1.3 0.51 97 970 all phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 0.985 0.924 – 1.05 0.646 1049 10478 all phecode
453 Chronic venous hypertension Circulatory System 1.04 0.772 – 1.1 0.706 88 869 all phecode
454 Varicose veins Circulatory System 1.01 0.955 – 1.07 0.679 1295 12776 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1.01 0.947 – 1.08 0.781 1047 10355 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.01 0.938 – 1.09 0.735 714 7102 all phecode
455 Hemorrhoids Circulatory System 1 0.963 – 1.05 0.852 2672 18295 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1 0.949 – 1.06 0.939 1441 13888 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.999 0.968 – 1.03 0.929 5130 20995 all phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 0.885 0.773 – 1.01 0.0751 238 2356 all phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 0.982 0.935 – 1.03 0.481 1843 13035 all phecode
458 Hypotension Circulatory System 0.982 0.945 – 1.02 0.357 3015 22648 all phecode
458.1 Orthostatic hypotension Circulatory System 0.994 0.92 – 1.07 0.87 709 7023 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.05 0.963 – 1.14 0.265 558 5562 all phecode
458.9 Hypotension NOS Circulatory System 0.973 0.932 – 1.02 0.228 2283 19889 all phecode
459 Other disorders of circulatory system Circulatory System 0.955 0.913 – 0.999 0.0471 2161 19021 all phecode
459.1 Hemorrhage NOS Circulatory System 0.942 0.836 – 1.06 0.327 304 3028 all phecode
459.7 Blood vessel replaced Circulatory System 1.01 0.839 – 1.22 0.89 123 1217 all phecode
459.9 Circulatory disease NEC Circulatory System 0.946 0.899 – 0.996 0.0352 1634 14997 all phecode
464 Acute sinusitis Respiratory 0.976 0.938 – 1.02 0.234 2849 21183 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.992 0.963 – 1.02 0.599 5573 24342 all phecode
465.2 Acute pharyngitis Respiratory 0.999 0.961 – 1.04 0.975 2925 20678 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.01 0.884 – 1.15 0.91 245 2450 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.968 0.904 – 1.04 0.358 939 9346 all phecode
471 Nasal polyps Respiratory 0.895 0.796 – 1.01 0.0624 324 3206 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.979 0.916 – 1.05 0.53 966 9545 all phecode
473 Diseases of the larynx and vocal cords Respiratory 0.966 0.917 – 1.02 0.204 1542 15343 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.968 0.867 – 1.08 0.566 358 3569 all phecode
473.4 Voice disturbance Respiratory 0.983 0.927 – 1.04 0.581 1200 11979 all phecode
474 Acute and chronic tonsillitis Respiratory 1 0.912 – 1.1 0.999 509 4696 all phecode
474.1 Acute tonsillitis Respiratory 1.01 0.787 – 1.05 0.894 184 1764 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.02 0.902 – 1.15 0.706 412 3832 all phecode
475 Chronic sinusitis Respiratory 0.975 0.932 – 1.02 0.271 2146 19495 all phecode
475.9 Postnasal drip Respiratory 0.994 0.877 – 1.13 0.929 274 2722 all phecode
476 Allergic rhinitis Respiratory 0.992 0.958 – 1.03 0.64 3745 22635 all phecode
477 Epistaxis or throat hemorrhage Respiratory 0.995 0.914 – 1.08 0.905 600 5948 all phecode
478 Throat pain Respiratory 0.912 0.781 – 1.06 0.237 186 1852 all phecode
479 Other upper respiratory disease Respiratory 0.99 0.952 – 1.03 0.613 2967 22638 all phecode
480 Pneumonia Respiratory 1.01 0.974 – 1.05 0.532 3008 24384 all phecode
480.1 Bacterial pneumonia Respiratory 1.03 0.944 – 1.13 0.469 524 5213 all phecode
480.11 Pneumococcal pneumonia Respiratory 0.988 0.798 – 1.22 0.912 102 1017 all phecode
480.12 Pseudomonal pneumonia Respiratory 0.902 0.721 – 1.12 0.351 89 887 all phecode
480.2 Viral pneumonia Respiratory 1.17 0.934 – 1.47 0.161 81 801 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.05 0.789 – 1.41 0.697 61 610 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.987 0.823 – 1.18 0.887 131 1300 all phecode
481 Influenza Respiratory 1.03 0.951 – 1.12 0.454 654 6500 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.01 0.969 – 1.06 0.55 2148 20399 all phecode
495 Asthma Respiratory 0.998 0.962 – 1.04 0.933 3166 22745 all phecode
495.1 Chronic obstructive asthma Respiratory 1.01 0.899 – 1.14 0.815 304 3023 all phecode
495.2 Asthma with exacerbation Respiratory 1.08 1 – 1.17 0.05 650 6488 all phecode
496 Chronic airway obstruction Respiratory 0.963 0.926 – 1 0.0554 2968 19630 all phecode
496.1 Emphysema Respiratory 0.985 0.932 – 1.04 0.589 1415 13515 all phecode
496.2 Chronic bronchitis Respiratory 1.03 0.96 – 1.1 0.407 863 8597 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.03 0.945 – 1.12 0.51 603 6024 all phecode
496.3 Bronchiectasis Respiratory 0.906 0.801 – 1.02 0.114 308 3063 all phecode
497 Bronchitis Respiratory 1.04 0.973 – 1.11 0.249 929 9246 all phecode
498 Acute bronchospasm Respiratory 0.92 0.787 – 1.07 0.291 177 1767 all phecode
499 Cystic fibrosis Respiratory 1.05 0.853 – 1.28 0.651 103 1030 all phecode
500 Lung disease due to external agents Respiratory 1.03 0.9 – 1.18 0.654 230 2286 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.01 0.783 – 1.29 0.956 67 670 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.04 0.932 – 1.16 0.463 343 3363 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.853 0.771 – 0.941 0.0016 460 4593 all phecode
503 Pulmonary congestion and hypostasis Respiratory 0.973 0.899 – 1.05 0.504 689 6829 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.866 0.769 – 0.973 0.0158 326 3248 all phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 0.912 0.786 – 1.05 0.215 208 2063 all phecode
505 Other pulmonary inflamation or edema Respiratory 0.919 0.859 – 0.982 0.0128 979 9753 all phecode
506 Empyema and pneumothorax Respiratory 0.963 0.923 – 1 0.0755 2507 20090 all phecode
507 Pleurisy; pleural effusion Respiratory 0.964 0.919 – 1.01 0.136 1912 17596 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.946 0.897 – 0.997 0.039 1534 15115 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 0.972 0.929 – 1.02 0.207 2166 18346 all phecode
509.1 Respiratory failure Respiratory 0.971 0.906 – 1.04 0.392 900 8982 all phecode
509.2 Respiratory insufficiency Respiratory 0.996 0.91 – 1.09 0.924 530 5292 all phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 0.956 0.898 – 1.02 0.151 1135 11297 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.982 0.905 – 1.06 0.655 647 6470 all phecode
510 Other diseases of lung Respiratory 0.974 0.941 – 1.01 0.131 3872 24663 all phecode
510.2 Lung transplant Respiratory 0.996 0.814 – 1.21 0.966 105 1050 all phecode
512 Other symptoms of respiratory system Respiratory 0.982 0.959 – 1.01 0.133 10908 19791 all phecode
512.1 Wheezing Respiratory 1.03 0.952 – 1.11 0.461 685 6775 all phecode
512.2 Painful respiration Respiratory 0.943 0.878 – 1.01 0.104 856 8524 all phecode
512.3 Abnormal chest sounds Respiratory 1.09 0.91 – 1.3 0.342 126 1253 all phecode
512.7 Shortness of breath Respiratory 0.995 0.965 – 1.03 0.737 5682 19763 all phecode
512.8 Cough Respiratory 0.973 0.944 – 1 0.0744 5445 19783 all phecode
512.9 Other dyspnea Respiratory 0.978 0.951 – 1.01 0.137 6302 19788 all phecode
513 Respiratory abnormalities Respiratory 0.981 0.948 – 1.02 0.291 3687 25516 all phecode
513.3 Hypoventilation Respiratory 0.879 0.771 – 1 0.052 262 2613 all phecode
513.31 Apnea Respiratory 0.921 0.759 – 1.11 0.393 121 1209 all phecode
513.32 Orthopnea Respiratory 0.902 0.683 – 1.18 0.446 58 579 all phecode
513.4 Hyperventilation Respiratory 1.23 1.06 – 1.41 0.00468 185 1840 all phecode
513.8 Disorders of diaphragm Respiratory 0.973 0.73 – 1 0.742 134 1340 all phecode
514 Abnormal findings examination of lungs Respiratory 1 0.964 – 1.04 0.961 3159 23315 all phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 1.04 0.841 – 1.27 0.727 96 954 all phecode
514.2 Solitary pulmonary nodule Respiratory 1 0.947 – 1.06 0.92 1275 12706 all phecode
516 Abnormal sputum Respiratory 1.01 0.91 – 1.13 0.812 370 3692 all phecode
516.1 Hemoptysis Respiratory 0.984 0.879 – 1.1 0.783 336 3354 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.976 0.944 – 1.01 0.148 4181 25923 all phecode
519.1 Tracheostomy complications Respiratory 0.908 0.736 – 1.12 0.361 98 980 all phecode
519.2 Respiratory complications Respiratory 0.962 0.83 – 1.11 0.602 211 2104 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.07 0.976 – 1.18 0.139 462 4597 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.969 0.935 – 1 0.081 3657 24661 all phecode
520 Disorders of tooth development Digestive 0.985 0.846 – 1.14 0.846 175 1748 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.734 0.554 – 0.96 0.0246 64 631 all phecode
520.2 Disturbances in tooth eruption Digestive 1.11 0.93 – 1.32 0.235 114 1118 all phecode
521 Diseases of hard tissues of teeth Digestive 0.942 0.842 – 1.05 0.288 358 3565 all phecode
521.1 Dental caries Digestive 0.945 0.843 – 1.06 0.329 338 3368 all phecode
522 Diseases of pulp and periapical tissues Digestive 0.962 0.834 – 1.11 0.593 206 2054 all phecode
522.5 Periapical abscess Digestive 0.952 0.816 – 1.11 0.523 180 1791 all phecode
523 Gingival and periodontal diseases Digestive 0.979 0.865 – 1.11 0.735 272 2710 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.07 0.912 – 1.26 0.387 150 1500 all phecode
523.31 Acute periodontitis Digestive 1.04 0.879 – 1.23 0.621 137 1370 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.93 0.727 – 1.15 0.379 147 1462 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.03 0.825 – 1.27 0.818 95 946 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.95 0.86 – 1.05 0.308 445 4447 all phecode
525.1 Loss of teeth or edentulism Digestive 0.98 0.798 – 1.2 0.841 109 1084 all phecode
526 Diseases of the jaws Digestive 0.99 0.93 – 1.05 0.759 1104 11028 all phecode
526.1 Cysts of the jaws Digestive 1.02 0.861 – 1.21 0.779 137 1353 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.05 0.883 – 1.24 0.582 140 1394 all phecode
526.4 Temporomandibular joint disorders Digestive 1.01 0.925 – 1.1 0.826 544 5440 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.985 0.885 – 1.1 0.777 368 3680 all phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 1.13 0.986 – 1.3 0.0747 221 2194 all phecode
526.5 Inflammatory conditions of jaw Digestive 0.905 0.731 – 1.12 0.351 104 1030 all phecode
526.9 Jaw disease NOS Digestive 0.958 0.832 – 1.1 0.549 214 2127 all phecode
527 Diseases of the salivary glands Digestive 0.941 0.873 – 1.01 0.108 765 7626 all phecode
527.2 Sialoadenitis Digestive 0.872 0.76 – 0.999 0.0496 231 2310 all phecode
527.7 Disturbance of salivary secretion Digestive 0.98 0.883 – 1.09 0.699 394 3924 all phecode
527.8 Other specified diseases of the salivary glands Digestive 0.948 0.782 – 1.15 0.579 125 1250 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.994 0.937 – 1.05 0.837 1241 12362 all phecode
528.1 Stomatitis and mucositis Digestive 1.07 0.951 – 1.21 0.247 284 2821 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.05 0.811 – 1.36 0.686 66 660 all phecode
528.12 Oral aphthae Digestive 1.09 0.9 – 1.32 0.368 116 1150 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.814 0.663 – 0.993 0.0442 107 1070 all phecode
528.4 Cysts of oral soft tissues Digestive 0.754 0.583 – 0.967 0.0268 73 722 all phecode
528.5 Diseases of lips Digestive 1.14 0.993 – 1.31 0.0595 207 2070 all phecode
528.6 Leukoplakia of oral mucosa Digestive 0.854 0.672 – 1.08 0.181 81 800 all phecode
528.7 Sialolithiasis Digestive 0.748 0.596 – 0.933 0.0103 92 920 all phecode
529 Diseases and other conditions of the tongue Digestive 0.912 0.816 – 1.02 0.101 357 3566 all phecode
529.1 Glossitis Digestive 0.932 0.731 – 1.18 0.558 75 750 all phecode
529.6 Glossodynia Digestive 0.982 0.766 – 1.25 0.879 66 660 all phecode
530 Diseases of esophagus Digestive 0.966 0.942 – 0.99 0.00644 9369 20357 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.968 0.944 – 0.993 0.0115 8940 20358 all phecode
530.11 GERD Digestive 0.967 0.942 – 0.992 0.0103 8565 20359 all phecode
530.12 Ulcer of esophagus Digestive 0.939 0.813 – 1.08 0.38 211 2110 all phecode
530.13 Barrett's esophagus Digestive 0.962 0.855 – 1.08 0.517 309 3081 all phecode
530.14 Reflux esophagitis Digestive 0.97 0.91 – 1.03 0.338 1072 10605 all phecode
530.15 Eosinophilic esophagitis Digestive 0.959 0.732 – 1.24 0.747 64 640 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.888 0.782 – 1.01 0.0641 278 2780 all phecode
530.3 Stricture and stenosis of esophagus Digestive 0.891 0.815 – 0.973 0.0104 554 5524 all phecode
530.5 Disorders of esophageal motility Digestive 1.05 0.931 – 1.19 0.418 283 2821 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.949 0.9 – 1.3 0.57 94 923 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.96 0.713 – 1.27 0.771 54 532 all phecode
530.9 Heartburn Digestive 0.987 0.917 – 1.06 0.715 800 7949 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.982 0.917 – 1.05 0.604 911 9101 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1 0.865 – 1.16 0.99 204 2027 all phecode
531.2 Gastric ulcer Digestive 0.98 0.89 – 1.08 0.689 453 4528 all phecode
531.3 Duodenal ulcer Digestive 0.852 0.735 – 0.984 0.03 211 2110 all phecode
531.4 Peptic ulcer, site unspecified Digestive 0.985 0.885 – 1.1 0.785 366 3654 all phecode
531.5 Gastrojejunal ulcer Digestive 1.07 0.865 – 1.11 0.479 67 651 all phecode
532 Dysphagia Digestive 0.945 0.908 – 0.983 0.00471 2947 18985 all phecode
535 Gastritis and duodenitis Digestive 0.923 0.867 – 0.983 0.0121 1122 11196 all phecode
535.1 Acute gastritis Digestive 0.995 0.771 – 1.28 0.968 75 750 all phecode
535.2 Atrophic gastritis Digestive 0.959 0.777 – 1.18 0.685 104 1040 all phecode
535.6 Duodenitis Digestive 0.815 0.694 – 0.954 0.011 181 1805 all phecode
535.8 Other specified gastritis Digestive 0.954 0.849 – 1.07 0.426 327 3251 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.941 0.861 – 1.03 0.176 568 5672 all phecode
536 Disorders of function of stomach Digestive 0.966 0.913 – 1.02 0.222 1381 13654 all phecode
536.3 Gastroparesis Digestive 1.05 0.929 – 1.19 0.425 275 2750 all phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.01 0.859 – 1.17 0.945 176 1752 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.946 0.888 – 1.01 0.0833 1083 10692 all phecode
537 Other disorders of stomach and duodenum Digestive 0.941 0.893 – 0.991 0.0212 1624 16210 all phecode
537.1 Lesions of stomach and duodenum Digestive 0.905 0.685 – 1.18 0.464 61 609 all phecode
539 Bariatric surgery Digestive 0.997 0.92 – 1.08 0.935 692 6920 all phecode
540 Appendiceal conditions Digestive 0.99 0.869 – 1.13 0.882 246 2460 all phecode
540.1 Appendicitis Digestive 1.01 0.873 – 1.16 0.916 203 2030 all phecode
540.11 Acute appendicitis Digestive 1.05 0.898 – 1.24 0.511 164 1640 all phecode
550 Abdominal hernia Digestive 0.964 0.931 – 0.997 0.0348 3863 25033 all phecode
550.1 Inguinal hernia Digestive 0.963 0.903 – 1.03 0.256 1025 10084 all phecode
550.2 Diaphragmatic hernia Digestive 0.977 0.927 – 1.03 0.388 1541 14916 all phecode
550.3 Femoral hernia Digestive 0.715 0.543 – 0.933 0.0137 68 680 all phecode
550.4 Umbilical hernia Digestive 0.93 0.862 – 1 0.0597 762 7620 all phecode
550.5 Ventral hernia Digestive 0.964 0.897 – 1.03 0.307 855 8521 all phecode
550.6 Incisional hernia Digestive 0.95 0.877 – 1.03 0.2 688 6880 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.07 0.998 – 1.15 0.0557 831 8236 all phecode
555.1 Regional enteritis Digestive 1.04 0.952 – 1.14 0.376 524 5211 all phecode
555.2 Ulcerative colitis Digestive 1.12 1.02 – 1.23 0.0145 478 4766 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.13 1.01 – 1.27 0.0343 305 3050 all phecode
556 Ulceration of the lower GI tract Digestive 0.902 0.802 – 1.01 0.0846 329 3280 all phecode
556.1 Ulceration of intestine Digestive 0.902 0.794 – 1.02 0.113 283 2808 all phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 0.894 0.71 – 0.916 0.198 78 779 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.993 0.915 – 1.08 0.868 644 6426 all phecode
557.1 Celiac disease Digestive 1.04 0.882 – 1.23 0.621 155 1550 all phecode
558 Noninfectious gastroenteritis Digestive 1.03 0.971 – 1.09 0.343 1284 12803 all phecode
559 Ileostomy status Digestive 0.988 0.904 – 1.08 0.786 553 5505 all phecode
560 Intestinal obstruction without mention of hernia Digestive 0.997 0.95 – 1.05 0.887 1864 16390 all phecode
560.1 Paralytic ileus Digestive 1.01 0.95 – 1.07 0.746 1152 11328 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.934 0.805 – 1.08 0.36 198 1974 all phecode
560.4 Other intestinal obstruction Digestive 0.988 0.928 – 1.05 0.71 1100 10934 all phecode
561 Symptoms involving digestive system Digestive 0.993 0.962 – 1.03 0.669 4882 19486 all phecode
561.1 Diarrhea Digestive 0.993 0.957 – 1.03 0.702 3477 19276 all phecode
561.2 Flatulence Digestive 0.956 0.908 – 1.01 0.0841 1632 15205 all phecode
562 Diverticulosis and diverticulitis Digestive 1 0.968 – 1.04 0.823 3634 16139 all phecode
562.1 Diverticulosis Digestive 1 0.967 – 1.04 0.866 3524 15965 all phecode
562.2 Diverticulitis Digestive 0.99 0.905 – 1.08 0.815 535 5299 all phecode
563 Constipation Digestive 0.993 0.959 – 1.03 0.701 3788 19204 all phecode
564 Functional digestive disorders Digestive 0.977 0.945 – 1.01 0.187 4139 19471 all phecode
564.1 Irritable Bowel Syndrome Digestive 0.979 0.926 – 1.03 0.438 1436 12835 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 0.969 0.924 – 1.02 0.197 1923 16754 all phecode
564.9 Personal history of diseases of digestive system Digestive 0.974 0.912 – 1.04 0.436 987 9822 all phecode
565 Anal and rectal conditions Digestive 1.01 0.957 – 1.06 0.836 1772 17627 all phecode
565.1 Anal and rectal polyp Digestive 1.01 0.927 – 1.09 0.903 670 6697 all phecode
567 Peritonitis and retroperitoneal infections Digestive 0.998 0.918 – 1.08 0.968 620 6174 all phecode
568 Other disorders of peritoneum Digestive 0.95 0.891 – 1.01 0.115 1063 10607 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 0.949 0.882 – 1.02 0.164 807 8070 all phecode
569 Other disorders of intestine Digestive 1 0.959 – 1.04 0.998 2439 22843 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.08 0.869 – 1.34 0.472 77 763 all phecode
569.2 Gastrointestinal complications Digestive 1.02 0.951 – 1.08 0.65 1013 10130 all phecode
571 Chronic liver disease and cirrhosis Digestive 0.98 0.935 – 1.03 0.38 1990 19480 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 0.983 0.936 – 1.03 0.498 1780 17776 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.01 0.913 – 1.11 0.869 431 4304 all phecode
571.6 Primary biliary cirrhosis Digestive 0.875 0.715 – 1.07 0.184 110 1100 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.962 0.876 – 1.06 0.42 491 4910 all phecode
571.81 Portal hypertension Digestive 0.957 0.852 – 1.07 0.451 320 3200 all phecode
572 Ascites (non malignant) Digestive 0.987 0.934 – 1.04 0.64 1427 14260 all phecode
573 Other disorders of liver Digestive 0.969 0.928 – 1.01 0.14 2426 21271 all phecode
573.1 Chronic passive congestion of liver Digestive 1.07 0.809 – 1.43 0.599 57 565 all phecode
573.2 Liver replaced by transplant Digestive 0.929 0.797 – 1.08 0.335 191 1901 all phecode
573.3 Hepatomegaly Digestive 0.875 0.72 – 1.06 0.172 123 1230 all phecode
573.4 Acute and subacute necrosis of liver Digestive 1.03 0.861 – 1.22 0.763 132 1317 all phecode
573.5 Jaundice (not of newborn) Digestive 0.959 0.872 – 1.05 0.379 477 4765 all phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.07 0.994 – 1.14 0.0726 870 8637 all phecode
573.7 Abnormal results of function study of liver Digestive 1 0.947 – 1.06 0.984 1398 13942 all phecode
573.9 Abnormal serum enzyme levels Digestive 0.975 0.92 – 1.03 0.386 1269 12656 all phecode
574 Cholelithiasis and cholecystitis Digestive 0.99 0.942 – 1.04 0.673 1798 17889 all phecode
574.1 Cholelithiasis Digestive 0.984 0.935 – 1.04 0.541 1628 16255 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1 0.859 – 1.16 0.983 178 1780 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.96 0.853 – 1.08 0.5 326 3260 all phecode
574.2 Calculus of bile duct Digestive 0.95 0.859 – 1.05 0.32 426 4249 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.998 0.909 – 1.09 0.968 491 4893 all phecode
575 Other biliary tract disease Digestive 0.976 0.922 – 1.03 0.393 1369 13683 all phecode
575.1 Cholangitis Digestive 0.92 0.798 – 1.06 0.24 224 2232 all phecode
575.2 Obstruction of bile duct Digestive 0.973 0.877 – 1.08 0.607 398 3970 all phecode
575.6 Cholesterolosis of gallbladder Digestive 1.17 0.948 – 1.44 0.135 101 1010 all phecode
575.7 Other disorders of gallbladder Digestive 1.02 0.932 – 1.11 0.72 586 5844 all phecode
575.8 Other disorders of biliary tract Digestive 0.916 0.843 – 0.994 0.0351 663 6625 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.09 0.889 – 1.33 0.402 99 990 all phecode
577 Diseases of pancreas Digestive 0.962 0.907 – 1.02 0.189 1282 12802 all phecode
577.1 Acute pancreatitis Digestive 0.961 0.879 – 1.05 0.379 550 5488 all phecode
577.2 Chronic pancreatitis Digestive 1.07 0.946 – 1.2 0.285 294 2940 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.921 0.822 – 1.03 0.15 347 3424 all phecode
578 Gastrointestinal hemorrhage Digestive 0.996 0.955 – 1.04 0.838 2525 23777 all phecode
578.1 Hematemesis Digestive 1.05 0.931 – 1.19 0.408 281 2803 all phecode
578.2 Blood in stool Digestive 1 0.952 – 1.06 0.917 1568 15580 all phecode
578.8 Hemorrhage of rectum and anus Digestive 0.94 0.884 – 0.998 0.0443 1169 11604 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.995 0.926 – 1.07 0.883 854 8501 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.01 0.972 – 1.05 0.63 3083 24286 all phecode
579.2 Splenomegaly Digestive 0.98 0.889 – 1.08 0.68 465 4646 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.975 0.891 – 1.07 0.575 523 5223 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.972 0.897 – 1.05 0.481 663 6626 all phecode
580.1 Glomerulonephritis Genitourinary 0.865 0.732 – 1.02 0.0839 160 1600 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.889 0.669 – 1.17 0.403 51 510 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.649 0.483 – 0.86 0.00283 64 639 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.03 0.78 – 1.35 0.837 55 544 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.934 0.727 – 1.19 0.586 78 780 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.972 0.886 – 1.07 0.549 499 4986 all phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.08 0.958 – 1.22 0.208 298 2977 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.929 0.813 – 1.06 0.274 256 2560 all phecode
580.4 Renal sclerosis, NOS Genitourinary 0.965 0.804 – 1.16 0.702 130 1300 all phecode
585 Renal failure Genitourinary 0.993 0.957 – 1.03 0.688 3458 20778 all phecode
585.1 Acute renal failure Genitourinary 0.99 0.947 – 1.04 0.672 2218 17709 all phecode
585.2 Renal failure NOS Genitourinary 1.06 0.97 – 1.16 0.191 530 5283 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1 0.961 – 1.05 0.832 2200 17131 all phecode
585.31 Renal dialysis Genitourinary 1.01 0.908 – 1.13 0.821 358 3580 all phecode
585.32 End stage renal disease Genitourinary 1.06 0.965 – 1.16 0.231 511 5109 all phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.01 0.94 – 1.08 0.83 882 8499 all phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.05 0.943 – 1.17 0.37 354 3533 all phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1 0.906 – 1.11 0.929 394 3919 all phecode
586 Other disorders of the kidney and ureters Genitourinary 0.979 0.948 – 1.01 0.207 4597 24047 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.03 0.876 – 1.21 0.712 162 1614 all phecode
586.11 Small kidney Genitourinary 1.05 0.836 – 1.32 0.65 78 777 all phecode
586.12 Vesicoureteral reflux Genitourinary 0.999 0.734 – 1.05 0.989 74 740 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.02 0.954 – 1.09 0.538 909 8889 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.13 0.93 – 1.38 0.208 107 1059 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.984 0.925 – 1.05 0.618 1121 11181 all phecode
587 Kidney replaced by transpant Genitourinary 1.06 0.97 – 1.17 0.184 488 4871 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1 0.909 – 1.1 0.962 451 4502 all phecode
588.1 Renal osteodystrophy Genitourinary 0.99 0.823 – 1.19 0.917 130 1296 all phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 0.943 0.811 – 1.09 0.438 190 1878 all phecode
589 Abnormal results of function study of kidney Genitourinary 0.988 0.913 – 1.07 0.761 684 6821 all phecode
590 Pyelonephritis Genitourinary 0.978 0.906 – 1.06 0.573 731 7290 all phecode
591 Urinary tract infection Genitourinary 0.984 0.955 – 1.01 0.289 5452 22952 all phecode
592 Cystitis and urethritis Genitourinary 0.979 0.921 – 1.04 0.488 1138 11348 all phecode
592.1 Cystitis Genitourinary 0.996 0.936 – 1.06 0.911 1068 10653 all phecode
592.11 Acute cystitis Genitourinary 0.962 0.879 – 1.05 0.396 533 5281 all phecode
592.12 Chronic cystitis Genitourinary 0.932 0.784 – 1.1 0.419 155 1536 all phecode
592.13 Chronic interstitial cystitis Genitourinary 1.04 0.91 – 1.19 0.548 232 2320 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.768 0.581 – 0.962 0.0255 81 802 all phecode
593 Hematuria Genitourinary 0.98 0.939 – 1.02 0.337 2486 21121 all phecode
593.1 Gross hematuria Genitourinary 0.94 0.861 – 1.03 0.167 562 5464 all phecode
593.2 Microscopic hematuria Genitourinary 0.955 0.838 – 1.09 0.481 260 2592 all phecode
594 Urinary calculus Genitourinary 1 0.964 – 1.04 0.9 2847 25144 all phecode
594.1 Calculus of kidney Genitourinary 1.01 0.973 – 1.06 0.52 2507 23747 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.04 0.91 – 1.19 0.544 230 2276 all phecode
594.3 Calculus of ureter Genitourinary 0.998 0.93 – 1.07 0.963 845 8428 all phecode
594.8 Renal colic Genitourinary 0.983 0.846 – 1.14 0.824 194 1940 all phecode
595 Hydronephrosis Genitourinary 0.993 0.931 – 1.06 0.82 1042 10410 all phecode
596 Other disorders of bladder Genitourinary 0.968 0.92 – 1.02 0.21 1681 15907 all phecode
596.1 Bladder neck obstruction Genitourinary 0.887 0.775 – 1.01 0.0803 250 2472 all phecode
596.5 Functional disorders of bladder Genitourinary 1.01 0.933 – 1.08 0.88 759 7579 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.974 0.901 – 1.05 0.508 693 6902 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.988 0.896 – 1.09 0.812 440 4350 all phecode
597.2 Urinary complications NEC Genitourinary 0.978 0.88 – 1.09 0.682 387 3857 all phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.09 0.872 – 1.38 0.424 83 820 all phecode
598 Abnormal findings on examination of urine Genitourinary 0.976 0.919 – 1.04 0.423 1201 11933 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.06 0.975 – 1.16 0.167 576 5735 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.98 0.954 – 1.01 0.13 7844 21512 all phecode
599.1 Urinary obstruction Genitourinary 0.927 0.705 – 0.96 0.171 305 3024 all phecode
599.2 Retention of urine Genitourinary 0.984 0.946 – 1.02 0.417 3032 19646 all phecode
599.3 Dysuria Genitourinary 0.967 0.925 – 1.01 0.147 2165 18489 all phecode
599.4 Urinary incontinence Genitourinary 1 0.963 – 1.04 0.99 3155 18822 all phecode
599.5 Frequency of urination and polyuria Genitourinary 0.983 0.945 – 1.02 0.384 2876 19849 all phecode
599.6 Oliguria and anuria Genitourinary 1.05 0.948 – 1.17 0.324 365 3643 all phecode
599.8 Other symptoms involving urinary system Genitourinary 0.974 0.932 – 1.02 0.233 2349 17485 all phecode
599.9 Other abnormality of urination Genitourinary 0.998 0.946 – 1.05 0.936 1498 14372 all phecode
600 Hyperplasia of prostate Genitourinary 0.972 0.925 – 1.02 0.263 2243 7947 all phecode
601 Inflammatory diseases of prostate Genitourinary 1.02 0.903 – 1.16 0.635 555 5331 all phecode
601.1 Prostatitis Genitourinary 1.05 0.905 – 1.23 0.396 266 2638 all phecode
601.11 Acute prostatitis Genitourinary 1.07 1.03 – 1.14 0.597 58 553 all phecode
601.12 Chronic prostatitis Genitourinary 1.13 1.09 – 1.19 0.252 53 509 all phecode
601.3 Orchitis and epididymitis Genitourinary 0.932 0.797 – 1.09 0.374 184 1815 all phecode
601.4 Balanoposthitis Genitourinary 0.729 0.562 – 0.937 0.014 71 698 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.04 1 – 1.09 0.677 81 782 all phecode
602 Other disorders of prostate Genitourinary 0.787 0.668 – 0.923 0.00343 178 1727 all phecode
603 Other disorders of testis Genitourinary 1 0.874 – 1.15 0.945 220 2192 all phecode
603.1 Hydrocele Genitourinary 0.936 0.792 – 1.1 0.434 162 1614 all phecode
603.2 Spermatocele Genitourinary 1.03 0.761 – 1.37 0.857 51 509 all phecode
604 Disorders of penis Genitourinary 0.961 0.858 – 1.07 0.489 354 3511 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.829 0.685 – 1 0.0503 129 1290 all phecode
604.3 Peyronie's disease Genitourinary 0.938 0.749 – 1.16 0.562 94 940 all phecode
605 Erectile dysfunction [ED] Genitourinary 0.985 0.931 – 1.04 0.585 1514 8788 all phecode
608 Other disorders of male genital organs Genitourinary 1.01 0.942 – 1.08 0.8 922 8988 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.09 0.895 – 1.15 0.199 225 2244 all phecode
609.1 Infertility, male Genitourinary 1.14 0.956 – 1.38 0.0965 177 1770 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.933 0.704 – 1.22 0.617 61 590 all phecode
610 Benign mammary dysplasias Genitourinary 1 0.956 – 1.05 0.996 2233 11530 all phecode
610.1 Cystic mastopathy Genitourinary 0.967 0.886 – 1.05 0.445 562 5522 all phecode
610.4 Benign neoplasm of breast Genitourinary 1.01 0.964 – 1.06 0.647 1942 11506 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.03 0.873 – 1.22 0.693 151 1490 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.991 0.956 – 1.03 0.615 4078 12749 all phecode
611.1 Abnormal mammogram Genitourinary 0.997 0.959 – 1.04 0.87 3365 11545 all phecode
611.11 Mammographic microcalcification Genitourinary 0.993 0.923 – 1.07 0.843 807 7873 all phecode
611.3 Lump or mass in breast Genitourinary 0.98 0.938 – 1.02 0.371 2397 12643 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.968 0.892 – 1.05 0.43 652 6511 all phecode
612.1 Galactorrhea Genitourinary 1.03 0.834 – 1.28 0.753 86 846 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.951 0.866 – 1.04 0.29 505 5050 all phecode
613 Other nonmalignant breast conditions Genitourinary 0.999 0.953 – 1.05 0.956 2083 14991 all phecode
613.1 Inflammatory disease of breast Genitourinary 1.09 0.98 – 1.22 0.107 356 3557 all phecode
613.5 Mastodynia Genitourinary 1 0.939 – 1.07 0.897 943 9313 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.988 0.905 – 1.08 0.794 544 5372 all phecode
613.8 Other specified disorders of breast Genitourinary 1.02 0.93 – 1.12 0.668 490 4900 all phecode
613.9 Breast disorder NOS Genitourinary 1.01 0.919 – 1.11 0.852 502 4996 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.994 0.95 – 1.04 0.809 2225 13521 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.961 0.833 – 1.11 0.582 218 2180 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.969 0.849 – 1.1 0.641 249 2490 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.12 0.922 – 1.36 0.243 110 1092 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.843 0.674 – 1.05 0.125 91 910 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.983 0.696 – 1.01 0.863 91 902 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1 0.953 – 1.05 0.986 1879 13146 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.948 0.806 – 1.11 0.512 157 1570 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.02 0.965 – 1.07 0.55 1634 12698 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.867 0.671 – 1.11 0.263 71 710 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.831 0.684 – 1 0.0553 127 1264 all phecode
615 Endometriosis Genitourinary 1.01 0.93 – 1.09 0.847 653 6530 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 0.91 0.778 – 1.06 0.234 185 1850 all phecode
618 Genital prolapse Genitourinary 0.945 0.885 – 1.01 0.0891 1010 9911 all phecode
618.1 Prolapse of vaginal walls Genitourinary 0.939 0.872 – 1.01 0.0908 813 8114 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.898 0.8 – 1.01 0.0659 331 3304 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.915 0.797 – 1.05 0.204 243 2412 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.943 0.737 – 1.19 0.614 78 780 all phecode
619 Noninflammatory female genital disorders Genitourinary 1 0.961 – 1.05 0.859 2418 13846 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.03 0.935 – 1.13 0.554 457 4566 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1.02 0.905 – 1.14 0.766 312 3113 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.01 0.885 – 1.15 0.881 251 2509 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.995 0.931 – 1.06 0.891 945 9337 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.979 0.897 – 1.07 0.638 555 5532 all phecode
620 Dysplasia of female genital organs Genitourinary 0.99 0.859 – 1.14 0.886 202 1998 all phecode
620.1 Dysplasia of cervix Genitourinary 1.02 0.787 – 1.32 0.87 65 642 all phecode
621 Endometrial hyperplasia Genitourinary 0.927 0.814 – 1.05 0.246 268 2670 all phecode
622 Polyp of female genital organs Genitourinary 0.968 0.905 – 1.03 0.335 963 9484 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.988 0.918 – 1.06 0.754 788 7783 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.971 0.854 – 1.1 0.643 262 2612 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.07 0.89 – 1.28 0.467 128 1275 all phecode
624 Symptoms involving female genital tract Genitourinary 0.967 0.882 – 1.06 0.475 509 5081 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.79 0.627 – 0.989 0.0402 86 849 all phecode
624.9 stress incontinence, female Genitourinary 1 0.939 – 1.06 0.997 1090 10634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.983 0.946 – 1.02 0.379 3565 11985 all phecode
625.1 Dyspareunia Genitourinary 0.973 0.892 – 1.06 0.535 577 5751 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.973 0.934 – 1.01 0.194 3133 10549 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.982 0.939 – 1.03 0.422 2526 9811 all phecode
626.11 Absent or infrequent menstruation Genitourinary 0.977 0.891 – 1.07 0.614 512 4742 all phecode
626.12 Excessive or frequent menstruation Genitourinary 0.958 0.902 – 1.02 0.164 1274 7706 all phecode
626.13 Irregular menstrual cycle Genitourinary 0.997 0.935 – 1.06 0.938 1045 7692 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.997 0.844 – 1.04 0.954 504 5031 all phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.995 0.826 – 1.04 0.944 233 2326 all phecode
626.2 Dysmenorrhea Genitourinary 0.909 0.836 – 0.988 0.0252 634 5538 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.925 0.789 – 1.08 0.317 184 1834 all phecode
626.8 Infertility, female Genitourinary 0.935 0.841 – 1.04 0.208 397 3631 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.01 0.965 – 1.05 0.703 2517 10696 all phecode
627.1 Postmenopausal bleeding Genitourinary 0.979 0.907 – 1.06 0.583 744 7177 all phecode
627.2 Symptomatic menopause Genitourinary 1 0.948 – 1.05 0.995 1581 10293 all phecode
627.21 Symptomatic artificial menopause Genitourinary 0.972 0.765 – 1.23 0.808 77 764 all phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 1.07 0.931 – 1.23 0.337 208 2080 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.05 0.874 – 1.1 0.264 443 4409 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.994 0.868 – 1.14 0.927 238 2371 all phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.914 0.741 – 1.12 0.39 109 1082 all phecode
628 Ovarian cyst Genitourinary 0.951 0.896 – 1.01 0.101 1250 9406 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.958 0.857 – 1.07 0.446 352 3520 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.945 0.817 – 0.981 0.409 158 1580 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.09 0.921 – 1.32 0.159 262 2614 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.05 0.873 – 1.27 0.532 165 1650 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.09 1.04 – 1.14 0.264 120 1200 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.95 0.873 – 1.03 0.236 627 4839 all phecode
636.1 Threatened premature labor Pregnancy Complications 1.01 0.771 – 1.06 0.853 193 1930 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.933 0.845 – 0.967 0.291 179 1790 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.932 0.821 – 0.965 0.23 253 2530 all phecode
638 Other high-risk pregnancy Pregnancy Complications 0.985 0.895 – 1.08 0.757 483 4437 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.928 0.753 – 0.955 0.202 229 2290 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.943 0.869 – 0.974 0.484 111 1110 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.946 0.77 – 1.16 0.588 106 1060 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.05 0.802 – 1.37 0.692 58 580 all phecode
644 Anemia during pregnancy Pregnancy Complications 0.882 0.816 – 0.912 0.291 53 530 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.96 0.828 – 1.11 0.58 203 2030 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.925 0.758 – 0.962 0.187 297 2968 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.03 0.82 – 1.29 0.78 109 1090 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.923 0.868 – 0.962 0.334 110 1095 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.947 0.87 – 1.03 0.205 631 4770 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.964 0.825 – 0.996 0.593 182 1820 all phecode
650 Normal delivery Pregnancy Complications 1 0.918 – 1.1 0.93 539 4838 all phecode
651 Multiple gestation Pregnancy Complications 0.996 0.781 – 1.26 0.972 76 760 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1.07 0.955 – 1.2 0.242 335 3346 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.999 0.884 – 1.13 0.984 294 2935 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 0.982 0.874 – 1.1 0.757 327 3270 all phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.04 0.913 – 1.2 0.484 269 2690 all phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 0.95 0.784 – 1.15 0.592 115 1150 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.02 0.946 – 1.09 0.646 861 6135 all phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 0.935 0.821 – 1.06 0.307 258 2580 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.07 0.899 – 1.26 0.453 149 1490 all phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 1.11 0.74 – 1.16 0.418 51 510 all phecode
658
Maternal complication of pregnancy affecting
Maternal complication of pregnancy affecting fetus or newborn
 Pregnancy Complications 0.93 0.767 – 1.12 0.454 121 1210 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 1 0.897 – 1.12 0.973 359 3399 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.892 0.782 – 1.01 0.0822 268 2664 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.956 0.874 – 1.05 0.329 545 4596 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.955 0.861 – 1.06 0.374 419 3688 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.985 0.911 – 1.02 0.838 120 1200 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.945 0.801 – 0.974 0.544 75 750 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.03 0.996 – 1.07 0.0832 3226 25620 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.06 0.965 – 1.16 0.233 502 5008 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.967 0.879 – 1.06 0.479 490 4878 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.03 0.933 – 1.14 0.535 425 4233 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.01 0.938 – 1.1 0.719 719 7170 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.949 0.836 – 1.08 0.416 275 2741 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.05 0.976 – 1.13 0.185 737 7337 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.03 0.956 – 1.11 0.445 772 7704 all phecode
686.1 Carbuncle and furuncle Dermatologic 0.996 0.889 – 1.11 0.942 332 3302 all phecode
686.2 Impetigo Dermatologic 1 0.709 – 1.04 0.989 117 1151 all phecode
686.3 Pilonidal cyst Dermatologic 1.23 0.985 – 1.53 0.0652 81 810 all phecode
686.4 Pyogenic granuloma Dermatologic 0.848 0.648 – 1.1 0.216 72 720 all phecode
687 Symptoms affecting skin Dermatologic 1 0.957 – 1.05 0.909 1923 18267 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.998 0.963 – 1.03 0.932 3507 23571 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1 0.948 – 1.05 0.997 1489 14692 all phecode
687.3 Changes in skin texture Dermatologic 0.984 0.803 – 1.2 0.878 108 1080 all phecode
687.4 Disturbance of skin sensation Dermatologic 0.985 0.948 – 1.02 0.424 3091 23515 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.12 1.09 – 1.16 1.39e-13 4922 25501 all phecode
690 Erythematosquamous dermatosis Dermatologic 1.12 1.04 – 1.21 0.00455 671 6685 all phecode
690.1 Seborrheic dermatitis Dermatologic 1.13 1.05 – 1.23 0.00162 662 6591 all phecode
691 Congenital anomalies of skin Dermatologic 0.927 0.812 – 1.05 0.251 252 2510 all phecode
694 Dyschromia and Vitiligo Dermatologic 1.06 0.988 – 1.15 0.101 733 7285 all phecode
694.1 Vitiligo Dermatologic 0.993 0.754 – 1.3 0.96 55 537 all phecode
694.2 Other dyschromia Dermatologic 1.07 0.989 – 1.16 0.0886 646 6423 all phecode
695 Erythematous conditions Dermatologic 1.01 0.969 – 1.06 0.57 2176 19590 all phecode
695.3 Rosacea Dermatologic 1.05 0.98 – 1.12 0.171 973 9708 all phecode
695.4 Lupus (localized and systemic) Dermatologic 0.946 0.849 – 1.05 0.307 385 3840 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.903 0.7 – 1.15 0.414 73 730 all phecode
695.42 Systemic lupus erythematosus Dermatologic 0.937 0.84 – 1.04 0.242 371 3699 all phecode
695.7 Prurigo and Lichen Dermatologic 0.981 0.869 – 1.1 0.753 283 2825 all phecode
695.8 Other specified erythematous conditions Dermatologic 1.02 0.921 – 1.13 0.709 392 3916 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.04 0.923 – 1.17 0.533 317 3160 all phecode
696 Psoriasis and related disorders Dermatologic 1.01 0.93 – 1.1 0.758 599 5979 all phecode
696.4 Psoriasis Dermatologic 1.02 0.934 – 1.11 0.654 558 5563 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.04 0.945 – 1.14 0.432 487 4851 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.08 0.917 – 1.27 0.347 162 1610 all phecode
697 Sarcoidosis Dermatologic 0.869 0.746 – 1.01 0.0656 200 2000 all phecode
698 Pruritus and related conditions Dermatologic 1.03 0.971 – 1.1 0.292 1083 10755 all phecode
700 Corns and callosities Dermatologic 0.933 0.847 – 1.03 0.154 489 4876 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.05 1.01 – 1.08 0.0156 3381 25494 all phecode
701.1 Keratoderma, acquired Dermatologic 1.02 0.875 – 1.19 0.78 189 1881 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.15 1.08 – 1.22 5.5e-06 1114 11124 all phecode
701.3 Circumscribed scleroderma Dermatologic 0.887 0.776 – 1.01 0.0734 252 2519 all phecode
701.4 Keloid scar Dermatologic 1.1 0.969 – 1.25 0.137 257 2556 all phecode
701.5 Abnormal granulation tissue Dermatologic 0.997 0.867 – 1.14 0.962 232 2299 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.15 1.11 – 1.19 1.18e-15 4029 20696 all phecode
702.1 Actinic keratosis Dermatologic 1.27 1.22 – 1.32 8.8e-30 2483 18119 all phecode
702.2 Seborrheic keratosis Dermatologic 1.12 1.08 – 1.17 3.46e-09 3023 20930 all phecode
703 Diseases of nail, NOS Dermatologic 1.01 0.923 – 1.11 0.802 518 5164 all phecode
703.1 Ingrowing nail Dermatologic 1.07 0.962 – 1.18 0.221 407 4057 all phecode
704 Diseases of hair and hair follicles Dermatologic 0.999 0.947 – 1.05 0.98 1477 14674 all phecode
704.1 Alopecia Dermatologic 0.952 0.877 – 1.03 0.232 665 6581 all phecode
704.2 Hirsutism Dermatologic 0.992 0.836 – 1.17 0.928 148 1473 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.02 0.95 – 1.1 0.532 749 7454 all phecode
705 Disorders of sweat glands Dermatologic 1.08 0.943 – 1.24 0.259 231 2304 all phecode
705.1 Dyshidrosis Dermatologic 1.15 0.914 – 1.48 0.217 75 747 all phecode
705.3 Hidradenitis Dermatologic 1.03 0.851 – 1.24 0.752 137 1355 all phecode
705.8 Hyperhidrosis Dermatologic 1.01 0.913 – 1.12 0.837 415 4140 all phecode
706 Diseases of sebaceous glands Dermatologic 1.09 1.05 – 1.14 9.11e-06 2769 24962 all phecode
706.1 Acne Dermatologic 1.01 0.94 – 1.08 0.822 890 8472 all phecode
706.2 Sebaceous cyst Dermatologic 1.12 1.06 – 1.18 1.47e-05 1566 15443 all phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 1.21 1.12 – 1.31 2.82e-06 655 6472 all phecode
707 Chronic ulcer of skin Dermatologic 0.992 0.926 – 1.06 0.821 929 9243 all phecode
707.1 Decubitus ulcer Dermatologic 0.984 0.883 – 1.09 0.764 388 3871 all phecode
707.2 Chronic ulcer of leg or foot Dermatologic 0.993 0.895 – 1.1 0.897 396 3934 all phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1.07 0.942 – 1.2 0.31 298 2980 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.987 0.905 – 1.08 0.772 568 5660 all phecode
709.2 Sicca syndrome Dermatologic 0.981 0.851 – 1.13 0.787 220 2195 all phecode
709.3 Systemic sclerosis Dermatologic 0.967 0.81 – 1.15 0.707 143 1430 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.97 0.851 – 1.1 0.639 262 2596 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.969 0.892 – 1.05 0.446 662 6611 all phecode
710.1 Osteomyelitis Musculoskeletal 0.959 0.882 – 1.04 0.329 633 6320 all phecode
710.11 Acute osteomyelitis Musculoskeletal 0.931 0.81 – 1.07 0.304 238 2380 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.984 0.85 – 1.14 0.826 204 2031 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.973 0.89 – 1.06 0.548 562 5610 all phecode
711 Arthropathy associated with infections Musculoskeletal 0.989 0.863 – 1.13 0.87 248 2473 all phecode
711.1 Pyogenic arthritis Musculoskeletal 0.993 0.904 – 1.02 0.925 148 1460 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.08 1.02 – 1.12 0.44 91 903 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.808 0.665 – 0.977 0.0287 135 1350 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 0.821 0.636 – 1.05 0.117 76 760 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 0.986 0.926 – 1.05 0.667 1068 10604 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.954 0.889 – 1.02 0.191 864 8611 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.96 0.868 – 1.06 0.416 443 4421 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.873 0.736 – 1.03 0.11 161 1601 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.931 0.751 – 1.15 0.504 100 1000 all phecode
716 Other arthropathies Musculoskeletal 0.965 0.935 – 0.997 0.0306 4694 22867 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.961 0.826 – 1.11 0.601 189 1888 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.901 0.8 – 1.01 0.0846 314 3120 all phecode
716.9 Arthropathy NOS Musculoskeletal 0.964 0.933 – 0.996 0.0274 4524 22669 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.993 0.826 – 1.19 0.936 122 1204 all phecode
720 Spinal stenosis Musculoskeletal 1.01 0.968 – 1.05 0.646 2399 19696 all phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1.02 0.966 – 1.07 0.512 1548 14271 all phecode
721 Spondylosis and allied disorders Musculoskeletal 0.996 0.959 – 1.03 0.834 3096 22029 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.01 0.967 – 1.05 0.774 2832 21530 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.947 0.863 – 1.04 0.239 525 5246 all phecode
721.8 Other allied disorders of spine Musculoskeletal 0.957 0.83 – 1.1 0.537 222 2220 all phecode
722 Intervertebral disc disorders Musculoskeletal 0.981 0.948 – 1.01 0.264 3951 24010 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.983 0.939 – 1.03 0.456 2109 20476 all phecode
722.3 Schmorl's nodes Musculoskeletal 0.957 0.78 – 1.17 0.663 109 1090 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1 0.963 – 1.05 0.873 2578 21752 all phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 0.984 0.88 – 1.1 0.772 356 3546 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.14 1.01 – 1.3 0.0321 271 2707 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.03 0.943 – 1.13 0.472 506 5051 all phecode
723 Other disorders of cervical region Musculoskeletal 0.977 0.891 – 1.07 0.626 489 4883 all phecode
723.1 Torticollis Musculoskeletal 1.09 0.885 – 1.33 0.421 101 1010 all phecode
724 Other and unspecified disorders of back Musculoskeletal 0.96 0.92 – 1 0.0573 2463 21769 all phecode
724.1 Disorders of sacrum Musculoskeletal 0.957 0.902 – 1.02 0.149 1250 12289 all phecode
724.2 Disorders of coccyx Musculoskeletal 0.967 0.888 – 1.05 0.435 596 5911 all phecode
724.8 Other symptoms referable to back Musculoskeletal 0.957 0.866 – 1.06 0.391 433 4324 all phecode
724.9 Other unspecified back disorders Musculoskeletal 0.966 0.908 – 1.03 0.273 1137 11318 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.998 0.969 – 1.03 0.891 5510 22783 all phecode
726.1 Enthesopathy Musculoskeletal 0.965 0.931 – 1 0.0536 3508 22767 all phecode
726.2 Synoviopathy Musculoskeletal 1.06 0.959 – 1.16 0.264 460 4596 all phecode
726.3 Bursitis Musculoskeletal 1.08 0.998 – 1.16 0.0549 718 7081 all phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 1.03 0.897 – 1.17 0.695 234 2331 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.02 0.98 – 1.05 0.376 3359 22495 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.01 0.96 – 1.07 0.635 1470 14554 all phecode
727.2 Bursitis disorders Musculoskeletal 0.943 0.808 – 1.1 0.454 183 1830 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1 0.927 – 1.08 0.989 754 7514 all phecode
727.5 Rupture of synovium Musculoskeletal 1.07 0.948 – 1.21 0.255 269 2671 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.01 0.946 – 1.08 0.724 942 9405 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.927 0.738 – 1.14 0.432 115 1150 all phecode
727.8 Plica syndrome Musculoskeletal 1.18 0.85 – 1.23 0.0774 88 879 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.04 0.936 – 1.16 0.442 373 3730 all phecode
728.1 Muscular calcification and ossification Musculoskeletal 1.06 0.921 – 1.09 0.629 60 590 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.02 0.87 – 1.2 0.767 159 1584 all phecode
728.7 Fasciitis Musculoskeletal 0.998 0.945 – 1.05 0.951 1429 14268 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.11 0.963 – 1.27 0.148 210 2100 all phecode
729 Other disorders of soft tissues Musculoskeletal 0.974 0.909 – 1.04 0.452 923 9227 all phecode
729.3 Panniculitis Musculoskeletal 0.809 0.623 – 1.04 0.0963 71 710 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.03 0.836 – 1.27 0.774 97 966 all phecode
732 Osteochondropathies Musculoskeletal 1.01 0.881 – 1.05 0.869 226 2239 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.01 0.67 – 1.05 0.912 117 1158 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.991 0.945 – 1.04 0.938 60 600 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.01 0.96 – 1.06 0.69 1629 14029 all phecode
733.2 Cyst of bone Musculoskeletal 0.947 0.778 – 1.15 0.582 112 1111 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1 0.889 – 1.12 0.997 306 3054 all phecode
733.6 Costochondritis Musculoskeletal 1.02 0.879 – 1.19 0.767 195 1950 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.929 0.835 – 1.03 0.168 400 3992 all phecode
733.9 Chondromalacia Musculoskeletal 0.903 0.644 – 0.934 0.392 70 700 all phecode
735 Acquired foot deformities Musculoskeletal 0.973 0.923 – 1.03 0.309 1543 15259 all phecode
735.1 Flat foot Musculoskeletal 0.973 0.859 – 1.1 0.664 277 2752 all phecode
735.2 Acquired toe deformities Musculoskeletal 0.988 0.906 – 1.08 0.787 577 5748 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.952 0.85 – 1.07 0.395 337 3360 all phecode
735.23 Hallux rigidus Musculoskeletal 0.994 0.863 – 1.14 0.933 210 2091 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.978 0.89 – 1.07 0.641 476 4744 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.972 0.884 – 1.07 0.563 474 4732 all phecode
736.2 Acquired deformities of finger Musculoskeletal 0.884 0.718 – 1.08 0.233 103 1030 all phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.984 0.744 – 1.29 0.906 59 590 all phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.958 0.806 – 1.13 0.619 143 1424 all phecode
737 Curvature of spine Musculoskeletal 1.01 0.938 – 1.09 0.801 796 7899 all phecode
737.1 Kyphosis (acquired) Musculoskeletal 1.11 0.973 – 1.27 0.113 229 2290 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.987 0.909 – 1.07 0.764 636 6302 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.988 0.933 – 1.05 0.675 1305 13004 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.971 0.891 – 1.06 0.499 576 5747 all phecode
739 Contracture of joint Musculoskeletal 0.961 0.848 – 1.09 0.531 274 2731 all phecode
740 Osteoarthrosis Musculoskeletal 1 0.971 – 1.03 0.979 6053 23703 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.994 0.956 – 1.03 0.76 3012 20262 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1 0.958 – 1.05 0.863 1983 17373 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.11 0.929 – 1.32 0.242 133 1323 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.959 0.893 – 1.03 0.241 853 8031 all phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 0.933 0.858 – 0.968 0.381 122 1210 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.999 0.969 – 1.03 0.937 5252 22975 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.03 0.99 – 1.06 0.156 3678 26204 all phecode
741.1 Ankylosis of joint Musculoskeletal 1.07 0.9 – 1.26 0.459 156 1558 all phecode
741.2 Stiffness of joint Musculoskeletal 0.98 0.894 – 1.07 0.67 504 5026 all phecode
741.3 Difficulty in walking Musculoskeletal 1.01 0.938 – 1.09 0.754 730 7244 all phecode
741.4 Joint effusions Musculoskeletal 1.04 0.981 – 1.1 0.183 1216 12099 all phecode
741.5 Hemarthrosis Musculoskeletal 1.12 1.09 – 1.17 0.35 55 550 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.02 0.966 – 1.08 0.434 1303 12204 all phecode
742.1 Loose body in joint Musculoskeletal 0.826 0.661 – 1.03 0.0852 95 934 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.942 0.672 – 0.979 0.393 186 1817 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.16 0.957 – 1.42 0.118 110 1069 all phecode
742.9 Other derangement of joint Musculoskeletal 1.03 0.972 – 1.1 0.29 1101 10498 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.01 0.982 – 1.04 0.467 5897 24672 all phecode
743.1 Osteoporosis Musculoskeletal 0.985 0.933 – 1.04 0.577 1593 10643 all phecode
743.11 Osteoporosis NOS Musculoskeletal 1.01 0.948 – 1.07 0.839 1248 9044 all phecode
743.12 Senile osteoporosis Musculoskeletal 0.98 0.91 – 1.05 0.588 783 6734 all phecode
743.13 Other specified osteoporosis Musculoskeletal 0.888 0.729 – 1.08 0.229 116 1160 all phecode
743.2 Pathologic fracture Musculoskeletal 1.02 0.923 – 1.12 0.732 443 4411 all phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 0.947 0.807 – 1.11 0.501 169 1680 all phecode
743.22 Pathologic fracture of femur Musculoskeletal 1.07 0.964 – 1.1 0.561 57 561 all phecode
743.4 Stress fracture Musculoskeletal 0.955 0.805 – 1.13 0.595 147 1458 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.02 0.985 – 1.05 0.307 5109 24535 all phecode
745 Pain in joint Musculoskeletal 1 0.98 – 1.03 0.751 10780 19904 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.02 0.961 – 1.07 0.587 1431 14023 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.993 0.934 – 1.05 0.819 1174 11472 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.967 0.863 – 1.08 0.553 340 3390 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.999 0.905 – 1.1 0.976 448 4459 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.947 0.866 – 1.03 0.23 549 5250 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.05 0.928 – 1.19 0.432 278 2771 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.88 0.683 – 1.12 0.304 72 710 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.1 0.977 – 1.24 0.11 293 2920 all phecode
749.1 Cleft palate Congenital Anomalies 0.97 0.904 – 1.03 0.814 54 511 all phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 1.11 1.04 – 1.16 0.35 64 633 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.967 0.882 – 1.06 0.467 521 5210 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.01 0.873 – 1.17 0.889 208 2080 all phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 1 0.785 – 1.27 0.997 84 840 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.94 0.836 – 1.06 0.295 311 3100 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.992 0.852 – 1.15 0.919 181 1802 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.906 0.752 – 1.09 0.29 132 1310 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.994 0.933 – 1.06 0.84 1070 10653 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.916 0.82 – 1.02 0.115 362 3599 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.964 0.849 – 1.09 0.568 263 2626 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.779 0.522 – 0.816 0.0304 82 810 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.991 0.915 – 1.07 0.829 664 6624 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.972 0.88 – 1.07 0.569 446 4432 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1 0.849 – 1.18 0.99 152 1515 all phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.11 0.888 – 1.38 0.347 84 838 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.07 0.947 – 1.21 0.266 276 2760 all phecode
752.1 Neural tube defects Congenital Anomalies 1.08 0.907 – 1.28 0.389 139 1390 all phecode
752.11 Spina bifida Congenital Anomalies 1.09 0.856 – 1.12 0.381 99 990 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.01 0.841 – 1.22 0.879 145 1441 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.984 0.794 – 1.21 0.882 95 950 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.961 0.881 – 1.05 0.361 579 5773 all phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 1 0.819 – 1.22 0.987 110 1100 all phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 1.02 0.902 – 1.15 0.759 285 2828 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.988 0.896 – 1.09 0.802 455 4519 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.03 0.879 – 1.2 0.741 191 1905 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.982 0.853 – 1.13 0.797 219 2175 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.02 0.855 – 1.2 0.851 141 1410 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.02 0.92 – 1.13 0.709 409 4080 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.01 0.787 – 1.28 0.948 75 732 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1 0.874 – 1.15 0.969 223 2227 all phecode
757 Congenital anomalies of the integument Congenital Anomalies 1.08 0.861 – 1.35 0.492 81 802 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.81 0.64 – 1.02 0.0735 88 880 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.864 0.828 – 0.885 0.245 59 583 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.943 0.812 – 1.08 0.334 285 2832 all phecode
760 Back pain Symptoms 0.999 0.973 – 1.02 0.919 8028 22659 all phecode
761 Cervicalgia Symptoms 0.985 0.951 – 1.02 0.389 3608 26610 all phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 0.988 0.94 – 1.04 0.617 1816 17997 all phecode
764 Sciatica Symptoms 0.973 0.921 – 1.03 0.331 1420 14178 all phecode
765 Cervical radiculitis Symptoms 1.05 0.979 – 1.14 0.161 752 7489 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.04 0.993 – 1.09 0.0931 1918 19040 all phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.11 1.02 – 1.16 0.314 80 784 all phecode
769 Nonallopathic lesions NEC Symptoms 0.964 0.894 – 1.04 0.334 761 7571 all phecode
770 Myalgia and myositis unspecified Symptoms 1.01 0.973 – 1.06 0.519 2597 20677 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.02 0.969 – 1.07 0.467 1684 16709 all phecode
771.1 Swelling of limb Symptoms 0.996 0.96 – 1.03 0.812 3385 24965 all phecode
771.2 Cramp of limb Symptoms 1.06 0.946 – 1.19 0.313 320 3173 all phecode
772 Symptoms of the muscles Symptoms 0.989 0.936 – 1.05 0.7 1393 13878 all phecode
772.1 Muscular wasting and disuse atrophy Symptoms 0.981 0.826 – 1.16 0.82 148 1480 all phecode
772.2 Spasm of muscle Symptoms 1.01 0.932 – 1.09 0.827 675 6750 all phecode
772.3 Muscle weakness Symptoms 0.996 0.929 – 1.07 0.904 869 8650 all phecode
772.4 Rhabdomyolysis Symptoms 1.04 0.845 – 1.26 0.729 107 1058 all phecode
772.6 Facial weakness Symptoms 0.984 0.846 – 1.14 0.836 188 1878 all phecode
773 Pain in limb Symptoms 0.998 0.972 – 1.02 0.873 7554 23129 all phecode
780 Hypothermia/Chills Symptoms 1.12 0.933 – 1.34 0.215 118 1176 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.03 0.928 – 1.13 0.616 426 4247 all phecode
782.3 Edema Symptoms 0.992 0.956 – 1.03 0.682 3242 24998 all phecode
782.6 Pallor and flushing Symptoms 1.06 0.95 – 1.19 0.288 333 2956 all phecode
783 Fever of unknown origin Symptoms 1.01 0.977 – 1.05 0.516 3640 27007 all phecode
783.1 Postprocedural fever Symptoms 1.02 0.846 – 1.23 0.82 127 1268 all phecode
785 Abdominal pain Symptoms 0.986 0.962 – 1.01 0.266 9622 21069 all phecode
788 Syncope and collapse Symptoms 0.994 0.949 – 1.04 0.786 1983 19629 all phecode
789 Nausea and vomiting Symptoms 1.01 0.978 – 1.04 0.63 5375 25291 all phecode
789.1 Persistent vomiting Symptoms 1.03 0.898 – 1.17 0.709 246 2442 all phecode
790 Nonspecific findings on examination of blood Symptoms 0.962 0.894 – 1.03 0.296 802 8010 all phecode
790.1 Elevated sedimentation rate Symptoms 0.897 0.672 – 1.15 0.372 67 662 all phecode
790.6 Other abnormal blood chemistry Symptoms 0.993 0.954 – 1.03 0.747 2593 24549 all phecode
790.9 Abnormal arterial blood gases Symptoms 1.12 0.899 – 1.39 0.307 90 900 all phecode
791 Gangrene Symptoms 1.13 0.89 – 1.43 0.303 75 750 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.975 0.912 – 1.04 0.465 972 8317 all phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Symptoms 0.974 0.889 – 1.07 0.571 510 5069 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.01 0.92 – 1.11 0.802 471 4684 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.03 0.953 – 1.12 0.433 672 6717 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.923 0.801 – 1.06 0.265 223 2230 all phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 0.91 0.807 – 1.02 0.116 310 3097 all phecode
795.8 Abnormal tumor markers Symptoms 0.895 0.731 – 1.09 0.272 115 1145 all phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 0.9 0.719 – 1.12 0.347 92 912 all phecode
796 Elevated prostate specific antigen [PSA] Symptoms 0.944 0.875 – 1.02 0.132 785 5994 all phecode
797 Shock Symptoms 0.954 0.839 – 1.08 0.47 274 2730 all phecode
797.1 Cardiogenic shock Symptoms 0.95 0.779 – 1.15 0.607 113 1122 all phecode
798 Malaise and fatigue Symptoms 1 0.974 – 1.03 0.886 6070 24586 all phecode
798.1 Chronic fatigue syndrome Symptoms 1.04 0.919 – 1.17 0.549 272 2700 all phecode
799 Debility unspecified Symptoms 1.03 0.966 – 1.11 0.327 928 9233 all phecode
800 Fracture of lower limb Injuries & Poisonings 0.978 0.918 – 1.04 0.5 1078 10737 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.05 0.939 – 1.17 0.384 331 3284 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.933 0.824 – 1.05 0.269 267 2668 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.969 0.88 – 1.07 0.525 468 4662 all phecode
800.4 Fracture of patella Injuries & Poisonings 0.948 0.813 – 1.1 0.492 179 1782 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.982 0.923 – 1.04 0.565 1127 11180 all phecode
801.1 Fracture of foot Injuries & Poisonings 0.927 0.852 – 1.01 0.0727 627 6238 all phecode
802 Fracture of pelvis Injuries & Poisonings 1.09 0.959 – 1.23 0.185 265 2636 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.996 0.934 – 1.06 0.892 1050 10314 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1 0.897 – 1.12 0.946 339 3390 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.94 0.862 – 1.02 0.156 596 5933 all phecode
803.21 Colles' fracture Injuries & Poisonings 0.941 0.813 – 1.09 0.409 211 2095 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.05 0.924 – 1.19 0.457 263 2618 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.988 0.916 – 1.06 0.751 759 7490 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.02 0.935 – 1.12 0.631 545 5436 all phecode
807 Fracture of ribs Injuries & Poisonings 0.96 0.852 – 1.08 0.496 296 2954 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.976 0.925 – 1.03 0.377 1498 14637 all phecode
817 Concussion Injuries & Poisonings 0.937 0.83 – 1.06 0.29 299 2962 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.946 0.784 – 1.13 0.514 139 1380 all phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.965 0.715 – 1.3 0.809 53 525 all phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 0.994 0.762 – 1.29 0.962 64 640 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.94 0.871 – 1.01 0.113 752 7462 all phecode
830 Dislocation Injuries & Poisonings 1.05 1 – 1.1 0.0365 2168 20638 all phecode
835 Internal derangement of knee Injuries & Poisonings 1.03 0.979 – 1.09 0.229 1359 13343 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.04 0.933 – 1.16 0.475 339 3375 all phecode
840 Sprains and strains Injuries & Poisonings 1.01 0.974 – 1.05 0.614 3421 25884 all phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 1.05 0.935 – 1.17 0.414 323 3220 all phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 1.02 0.945 – 1.1 0.643 786 7859 all phecode
840.3 Joint/ligament sprain Injuries & Poisonings 1.02 0.954 – 1.1 0.507 822 7524 all phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.968 0.894 – 1.05 0.412 674 6740 all phecode
842 Other sprains and strains Injuries & Poisonings 1.07 0.974 – 1.17 0.165 529 5280 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.03 0.966 – 1.09 0.411 1214 12140 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.11 0.989 – 1.24 0.0743 334 3319 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.14 0.991 – 1.3 0.0652 224 2229 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1 0.93 – 1.08 0.932 758 7566 all phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.03 0.901 – 1.18 0.661 246 2454 all phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.09 0.946 – 1.25 0.231 217 2170 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.04 0.965 – 1.12 0.295 725 7209 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.95 0.897 – 1 0.0744 1347 13408 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 0.991 0.936 – 1.05 0.755 1318 13150 all phecode
860 Bone marrow or stem cell transplant Neoplasms 0.934 0.74 – 1.17 0.553 85 848 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 0.993 0.949 – 1.04 0.776 2111 20830 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.908 0.77 – 1.07 0.242 174 1740 all phecode
870.2 Open wound of ear Injuries & Poisonings 1.02 0.761 – 1.35 0.911 65 641 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.08 0.99 – 1.17 0.0842 579 5766 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1 0.831 – 1.21 0.972 124 1227 all phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 0.861 0.722 – 1.02 0.0886 147 1470 all phecode
870.6 Open wound of neck Injuries & Poisonings 1 0.856 – 1.17 0.967 168 1673 all phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.04 0.79 – 1.36 0.776 61 610 all phecode
871 Open wounds of extremities Injuries & Poisonings 0.981 0.932 – 1.03 0.471 1620 16154 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.985 0.865 – 1.12 0.811 264 2640 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.03 0.941 – 1.14 0.481 495 4947 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.15 0.99 – 1.34 0.0639 174 1740 all phecode
871.4 Open wound of toe(s) Injuries & Poisonings 0.962 0.779 – 1.19 0.717 103 1030 all phecode
872 Traumatic amputation Injuries & Poisonings 1.01 0.883 – 1.15 0.894 242 2420 all phecode
873 Broken tooth Injuries & Poisonings 0.942 0.721 – 1.21 0.634 68 663 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.14 1.07 – 1.18 0.204 79 780 all phecode
875 Non-healing surgical wound Injuries & Poisonings 0.998 0.892 – 1.12 0.973 350 3500 all phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.12 1 – 1.26 0.0487 297 2950 all phecode
907 Injuries to the nervous system Injuries & Poisonings 0.958 0.884 – 1.04 0.296 682 6797 all phecode
910 Superficial injury, infected Injuries & Poisonings 0.868 0.647 – 1.15 0.328 59 590 all phecode
911 Blister Injuries & Poisonings 1.1 0.838 – 1.48 0.459 56 560 all phecode
912 Insect bite Injuries & Poisonings 1.08 0.915 – 1.26 0.364 154 1540 all phecode
913 Toxic effect of venom Injuries & Poisonings 1.04 0.877 – 1.23 0.658 146 1460 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 0.997 0.935 – 1.06 0.931 1040 10341 all phecode
916 Contusion Injuries & Poisonings 1.01 0.964 – 1.06 0.673 1914 19035 all phecode
930 Allergic reaction to food Injuries & Poisonings 1.05 0.951 – 1.16 0.333 444 4430 all phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Injuries & Poisonings 0.996 0.887 – 1.12 0.94 333 3318 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.16 1.12 – 1.21 6.41e-15 2959 20675 all phecode
938.1 Acute dermatitis due to solar radiation Injuries & Poisonings 1.24 1.01 – 1.53 0.0392 90 898 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 1.17 1.13 – 1.22 1.24e-15 2842 20396 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.02 0.984 – 1.06 0.271 3339 23216 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.06 0.772 – 1.1 0.496 124 1230 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.02 0.865 – 1.19 0.827 168 1680 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.07 0.943 – 1.22 0.276 254 2540 all phecode
947 Urticaria Injuries & Poisonings 1 0.922 – 1.09 0.926 590 5884 all phecode
949 Allergies, other Injuries & Poisonings 1.02 0.975 – 1.07 0.354 1859 16941 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.954 0.806 – 1.13 0.58 163 1621 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.932 0.893 – 0.96 0.528 51 495 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.01 0.909 – 1.12 0.882 408 4075 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.07 0.859 – 1.34 0.531 92 919 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.985 0.764 – 1.26 0.903 66 656 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.02 0.976 – 1.07 0.368 2104 18862 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.01 0.958 – 1.07 0.674 1466 14384 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.07 0.968 – 1.18 0.187 442 4420 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.967 0.904 – 1.03 0.323 973 9595 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.07 0.961 – 1.19 0.219 371 3695 all phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.06 0.929 – 1.2 0.403 253 2525 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.88 – 1.26 0.559 124 1233 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.04 0.982 – 1.1 0.178 1308 13062 all phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.04 0.984 – 1.1 0.161 1273 12711 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.04 0.882 – 1.22 0.642 159 1590 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.07 0.894 – 1.28 0.452 133 1330 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.949 0.877 – 1.03 0.194 687 6861 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.943 0.885 – 1 0.0713 1086 10815 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.11 0.846 – 1.46 0.426 54 540 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.996 0.897 – 1.1 0.942 387 3866 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 0.889 0.775 – 1.02 0.09 241 2401 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.02 0.77 – 1.35 0.891 51 495 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.01 0.861 – 1.17 0.944 177 1762 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.976 0.779 – 1.22 0.829 89 890 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.978 0.927 – 1.03 0.41 1551 14658 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.05 0.978 – 1.12 0.191 959 9559 all phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 0.934 0.852 – 1.02 0.142 521 5202 all phecode
983
Toxic effect of corrosive aromatics, acids, and
Toxic effect of corrosive aromatics, acids, and caustic alkalis
 Injuries & Poisonings 1.06 0.837 – 1.33 0.628 76 760 all phecode
990 Effects radiation NOS Injuries & Poisonings 0.981 0.935 – 1.03 0.424 1897 17875 all phecode
994 Sepsis and SIRS Injuries & Poisonings 0.986 0.926 – 1.05 0.664 1083 10796 all phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.01 0.828 – 1.23 0.918 110 1100 all phecode
994.2 Sepsis Injuries & Poisonings 1 0.937 – 1.07 0.992 1029 10259 all phecode
994.21 Septic shock Injuries & Poisonings 1.03 0.891 – 1.18 0.725 225 2240 all phecode
008 Intestinal infection Infectious Diseases 0.937 0.882 – 0.994 0.031 1500 14936 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 0.961 0.877 – 1.05 0.39 666 6643 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.954 0.865 – 1.05 0.339 585 5839 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 0.886 0.794 – 0.987 0.0284 433 4330 exclusion phecode
010 Tuberculosis Infectious Diseases 0.949 0.735 – 1.22 0.682 80 793 exclusion phecode
038 Septicemia Infectious Diseases 0.996 0.934 – 1.06 0.899 1305 12978 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 0.986 0.864 – 1.12 0.835 320 3178 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.04 0.852 – 1.26 0.697 133 1330 exclusion phecode
038.3 Bacteremia Infectious Diseases 0.966 0.871 – 1.07 0.5 532 5278 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 0.983 0.942 – 1.03 0.423 2913 26150 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.03 0.956 – 1.11 0.427 929 9277 exclusion phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 0.947 0.834 – 1.07 0.39 347 3458 exclusion phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.05 0.927 – 1.2 0.415 301 3010 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1 0.923 – 1.08 0.997 797 7962 exclusion phecode
041.4 E. coli Infectious Diseases 0.92 0.841 – 1.01 0.0676 667 6644 exclusion phecode
041.8 H. pylori Infectious Diseases 1.03 0.983 – 1.07 0.789 82 766 exclusion phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 0.964 0.892 – 1 0.658 152 1510 exclusion phecode
053 Herpes zoster Infectious Diseases 0.97 0.884 – 1.06 0.51 663 6615 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.802 0.624 – 1.02 0.0771 102 1019 exclusion phecode
054 Herpes simplex Infectious Diseases 0.982 0.897 – 1.07 0.69 619 6147 exclusion phecode
070 Viral hepatitis Infectious Diseases 0.947 0.845 – 1.06 0.343 402 4013 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 0.989 0.942 – 1.02 0.925 63 620 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.01 0.893 – 1.15 0.828 308 3071 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 0.969 0.721 – 1.01 0.753 132 1311 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 0.996 0.89 – 1.11 0.943 422 4214 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.22 0.948 – 1.55 0.113 70 700 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.23 0.91 – 1.66 0.163 52 520 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.96 0.908 – 1.01 0.145 1812 17996 exclusion phecode
079 Viral infection Infectious Diseases 0.946 0.893 – 1 0.0574 1526 14924 exclusion phecode
079.2 Infectious mononucleosis Infectious Diseases 0.941 0.897 – 0.975 0.506 107 1046 exclusion phecode
080 Postoperative infection Infectious Diseases 0.985 0.934 – 1.04 0.558 1946 19388 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 0.972 0.907 – 1.04 0.408 1080 10767 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.06 0.887 – 1.27 0.484 201 2010 exclusion phecode
1000 Burns Injuries & Poisonings 0.929 0.823 – 1.05 0.223 354 3532 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 1.01 0.953 – 1.06 0.797 1707 16964 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1 0.964 – 1.04 0.94 3861 26353 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.01 0.915 – 1.05 0.875 139 1373 exclusion phecode
1005 Other symptoms Injuries & Poisonings 1.01 0.968 – 1.06 0.548 2419 23166 exclusion phecode
1006 Crushing injury Injuries & Poisonings 1.14 0.959 – 1.38 0.114 162 1612 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 1.07 0.937 – 1.22 0.314 280 2800 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 0.918 0.832 – 1.01 0.0845 569 5646 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 1 0.969 – 1.04 0.846 4515 26171 exclusion phecode
1010 Other tests Injuries & Poisonings 0.982 0.957 – 1.01 0.157 11545 19151 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 0.98 0.937 – 1.03 0.392 2557 24998 exclusion phecode
1012 Late effect Injuries & Poisonings 0.967 0.744 – 1.02 0.617 253 2520 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.03 0.973 – 1.08 0.341 1794 17855 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.959 0.89 – 1.01 0.733 71 710 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 0.983 0.935 – 1.03 0.519 2084 20811 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.03 0.956 – 1.11 0.428 918 9171 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.01 0.955 – 1.07 0.719 1707 16828 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 1.01 0.95 – 1.07 0.794 1585 15622 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.996 0.922 – 1.07 0.91 925 9188 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.04 0.926 – 1.17 0.493 411 4088 exclusion phecode
110.13 Dermatophytosis of the body Infectious Diseases 0.989 0.876 – 1.11 0.854 393 3913 exclusion phecode
110.2 Dermatomycoses Infectious Diseases 1.12 0.934 – 1.33 0.216 159 1581 exclusion phecode
1100 Family history Injuries & Poisonings 0.979 0.804 – 1.19 0.832 138 1375 exclusion phecode
112 Candidiasis Infectious Diseases 1.07 1.02 – 1.13 0.00819 1931 19005 exclusion phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.18 1.05 – 1.33 0.00578 362 3620 exclusion phecode
117 Mycoses Infectious Diseases 0.952 0.834 – 1.09 0.465 287 2852 exclusion phecode
117.1 Histoplasmosis Infectious Diseases 1.02 0.994 – 1.08 0.891 52 520 exclusion phecode
117.4 Aspergillosis Infectious Diseases 0.986 0.931 – 1.02 0.908 63 619 exclusion phecode
130 Spirochetal infection Infectious Diseases 1 0.92 – 1.03 0.998 67 667 exclusion phecode
132 Infestation (lice, mites) Infectious Diseases 0.828 0.649 – 1.05 0.117 96 955 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.996 0.919 – 1.08 0.912 815 8099 exclusion phecode
145 Cancer of mouth Neoplasms 0.984 0.897 – 1.08 0.721 886 8808 exclusion phecode
145.2 Cancer of tongue Neoplasms 0.997 0.878 – 1.13 0.962 417 4154 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 1.02 0.932 – 1.06 0.836 218 2162 exclusion phecode
145.4 Cancer of the gums Neoplasms 0.943 0.906 – 0.992 0.593 112 1109 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 0.972 0.92 – 1.03 0.738 130 1289 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.961 0.845 – 1.08 0.367 830 8259 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 0.886 0.812 – 0.924 0.103 204 2021 exclusion phecode
149.2 Cancer of nasopharynx Neoplasms 0.97 0.707 – 1.32 0.844 63 630 exclusion phecode
149.3 Cancer of hypopharynx Neoplasms 0.929 0.653 – 1.3 0.668 53 526 exclusion phecode
149.4 Cancer of larynx Neoplasms 0.992 0.782 – 1.04 0.911 256 2558 exclusion phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 1.04 0.889 – 1.21 0.604 368 3672 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 0.978 0.806 – 1.02 0.81 159 1582 exclusion phecode
150 Cancer of esophagus Neoplasms 0.939 0.82 – 1.07 0.353 293 2917 exclusion phecode
151 Cancer of stomach Neoplasms 0.9 0.735 – 1.07 0.129 259 2582 exclusion phecode
153 Colorectal cancer Neoplasms 1.08 0.991 – 1.17 0.0785 806 8045 exclusion phecode
153.2 Colon cancer Neoplasms 1.06 0.963 – 1.16 0.242 617 6150 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.1 0.992 – 1.23 0.0674 494 4922 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.06 0.928 – 1.21 0.388 296 2960 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.07 0.922 – 1.24 0.356 221 2210 exclusion phecode
157 Pancreatic cancer Neoplasms 0.934 0.82 – 1.06 0.301 313 3130 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.967 0.894 – 1.04 0.394 904 8981 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.962 0.881 – 1.05 0.384 667 6658 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.975 0.797 – 1.19 0.8 123 1225 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.939 0.83 – 0.983 0.532 104 1040 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.979 0.829 – 1.15 0.802 189 1883 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 1.24 0.969 – 1.28 0.0649 93 930 exclusion phecode
165 Cancer within the respiratory system Neoplasms 0.988 0.91 – 1.07 0.773 851 8499 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1 0.915 – 1.09 0.998 707 7060 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 1.01 0.931 – 1.09 0.817 1146 11400 exclusion phecode
170.1 Bone cancer Neoplasms 0.966 0.849 – 1.09 0.572 496 4942 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1.01 0.916 – 1.11 0.87 817 8145 exclusion phecode
172 Skin cancer Neoplasms 1.01 0.914 – 1.05 0.963 4503 22747 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.01 0.922 – 1.05 0.958 1896 16354 exclusion phecode
172.11 Melanomas of skin Neoplasms 1.01 0.927 – 1.05 0.958 1772 15654 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1.01 0.912 – 1.05 0.96 3220 19453 exclusion phecode
172.21 Basal cell carcinoma Neoplasms 1.01 0.93 – 1.06 0.955 1303 11426 exclusion phecode
172.22 Squamous cell carcinoma Neoplasms 1.01 0.933 – 1.05 0.965 836 7436 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 1.02 0.929 – 1.05 0.956 896 7983 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.979 0.899 – 1.07 0.628 1203 11716 exclusion phecode
174 Breast cancer Neoplasms 1.02 0.973 – 1.08 0.364 2106 11124 exclusion phecode
174.1 Breast cancer [female] Neoplasms 1.02 0.967 – 1.07 0.494 2025 10599 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.02 0.964 – 1.07 0.538 1963 10559 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.16 0.926 – 1.44 0.191 103 1019 exclusion phecode
175 Acquired absence of breast Neoplasms 1.01 0.937 – 1.09 0.752 797 7748 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.01 0.943 – 1.09 0.728 940 8967 exclusion phecode
180.1 Cervical cancer Neoplasms 1.04 0.943 – 1.15 0.405 461 4610 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1 0.911 – 1.1 0.997 551 5388 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 1.03 0.93 – 1.14 0.567 471 4691 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1 0.924 – 1.08 1 857 8412 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.05 0.958 – 1.16 0.284 548 5471 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.04 0.937 – 1.14 0.487 473 4727 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.897 0.791 – 1.02 0.0884 381 3805 exclusion phecode
185 Cancer of prostate Neoplasms 0.959 0.903 – 1.02 0.171 1794 7800 exclusion phecode
187 Cancer of other male genital organs Neoplasms 0.968 0.885 – 1.06 0.484 685 6451 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.968 0.878 – 1.07 0.509 592 5545 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.96 0.872 – 1.06 0.401 597 5698 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.993 0.94 – 1.05 0.804 1793 15041 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.969 0.894 – 1.05 0.453 812 8117 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.965 0.887 – 1.05 0.395 754 7538 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.928 0.768 – 1.12 0.43 156 1548 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.01 0.944 – 1.08 0.754 1147 10019 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.01 0.946 – 1.09 0.683 1058 9254 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.04 0.934 – 1.16 0.459 442 4279 exclusion phecode
190 Cancer of eye Neoplasms 0.957 0.899 – 1 0.744 79 784 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.973 0.884 – 1.07 0.576 606 6032 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.955 0.847 – 1.07 0.44 400 4000 exclusion phecode
191.11 Cancer of brain Neoplasms 0.959 0.842 – 1.09 0.52 324 3231 exclusion phecode
193 Thyroid cancer Neoplasms 1.01 0.921 – 1.11 0.844 589 5872 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.03 0.857 – 1.24 0.729 160 1593 exclusion phecode
195 Cancer, suspected or other Neoplasms 1 0.964 – 1.04 0.846 4418 20000 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 0.999 0.955 – 1.04 0.961 3448 18667 exclusion phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 0.981 0.652 – 1.02 0.713 629 6217 exclusion phecode
196 Radiotherapy Neoplasms 0.976 0.908 – 1.05 0.494 1207 11404 exclusion phecode
197 Chemotherapy Neoplasms 1.02 0.97 – 1.06 0.514 2690 19063 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1 0.96 – 1.05 0.92 3734 19920 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.994 0.941 – 1.05 0.839 2389 18093 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.947 0.86 – 1.04 0.267 680 6798 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.952 0.86 – 1.05 0.342 522 5213 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.12 1 – 1.25 0.0473 453 4509 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.83 0.717 – 0.959 0.0113 387 3851 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 0.948 0.889 – 1.01 0.297 481 4787 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.979 0.912 – 1.04 0.813 210 2091 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 0.983 0.944 – 1.02 0.407 3670 20946 exclusion phecode
199.4 Neurofibromatosis Neoplasms 0.826 0.601 – 1.13 0.225 58 580 exclusion phecode
200 Myeloproliferative disease Neoplasms 0.964 0.879 – 1.06 0.435 651 6500 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.1 0.851 – 1.42 0.445 78 777 exclusion phecode
201 Hodgkin's disease Neoplasms 0.984 0.782 – 1.23 0.889 100 994 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.998 0.923 – 1.08 0.956 1008 10059 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.01 0.935 – 1.1 0.746 937 9351 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1 0.909 – 1.1 0.956 616 6150 exclusion phecode
202.24 Large cell lymphoma Neoplasms 0.944 0.721 – 1.23 0.667 79 782 exclusion phecode
204 Leukemia Neoplasms 0.999 0.881 – 1.13 0.987 379 3786 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 0.946 0.903 – 0.986 0.546 138 1380 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.949 0.737 – 1.21 0.677 102 1012 exclusion phecode
204.2 Myeloid leukemia Neoplasms 0.985 0.799 – 1.21 0.888 127 1270 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 1.02 0.81 – 1.27 0.87 100 1000 exclusion phecode
204.4 Multiple myeloma Neoplasms 1.02 0.975 – 1.09 0.848 130 1271 exclusion phecode
208 Benign neoplasm of colon Neoplasms 0.991 0.959 – 1.02 0.59 5516 24179 exclusion phecode
209 Neuroendocrine tumors Neoplasms 0.964 0.787 – 1.18 0.721 124 1240 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.949 0.885 – 1.02 0.139 1162 11576 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.987 0.952 – 1.02 0.489 3981 24743 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.967 0.906 – 1.03 0.318 1191 11900 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.969 0.902 – 1.04 0.378 1007 9971 exclusion phecode
214 Lipoma Neoplasms 0.917 0.843 – 0.997 0.044 759 7562 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.917 0.818 – 1.03 0.131 403 4023 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.96 0.911 – 1.01 0.127 1969 19655 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.963 0.931 – 0.996 0.03 6667 23883 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.969 0.875 – 1.01 0.539 530 5254 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.956 0.869 – 0.997 0.374 481 4772 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.98 0.937 – 1.03 0.381 2613 11674 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 1.04 0.969 – 1.11 0.278 979 9396 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.97 0.924 – 1.02 0.216 2183 11323 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.979 0.897 – 1.07 0.633 608 6015 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.03 0.967 – 1.1 0.334 1125 10048 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.921 0.838 – 1.01 0.0811 648 6377 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.985 0.92 – 1.05 0.655 1120 8638 exclusion phecode
224 Benign neoplasm of eye Neoplasms 1.12 0.998 – 1.27 0.0517 388 3858 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.15 1.01 – 1.31 0.0305 329 3255 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.987 0.906 – 1.07 0.765 741 7403 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.962 0.874 – 1.06 0.432 576 5754 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.05 0.878 – 1.25 0.593 177 1770 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.951 0.878 – 1.03 0.215 787 7859 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1 0.932 – 1.07 0.977 930 9289 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 0.949 0.824 – 1.09 0.464 249 2480 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.02 0.914 – 1.13 0.759 427 4222 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.11 0.971 – 1.27 0.123 255 2543 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.946 0.87 – 1.03 0.186 902 9000 exclusion phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.941 0.819 – 1.08 0.388 351 3510 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.01 0.973 – 1.04 0.648 5138 25300 exclusion phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 1.01 0.964 – 1.05 0.798 3627 23859 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.975 0.886 – 1.07 0.608 553 5508 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.954 0.898 – 1.01 0.132 1431 13548 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.964 0.902 – 1.03 0.282 1183 11806 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.945 0.865 – 1.03 0.201 664 6625 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.02 0.933 – 1.11 0.687 677 6736 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 1.01 0.883 – 1.16 0.869 248 2461 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.06 0.827 – 1.36 0.617 76 760 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.991 0.807 – 1.21 0.931 126 1249 exclusion phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.943 0.707 – 1.24 0.678 60 598 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.02 0.981 – 1.05 0.351 4513 22753 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.02 0.947 – 1.1 0.581 872 8700 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.967 0.858 – 1.09 0.577 378 3763 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.01 0.978 – 1.05 0.448 4206 22146 exclusion phecode
245 Thyroiditis Endocrine/metabolic 1.05 0.931 – 1.19 0.417 346 3448 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.03 0.901 – 1.18 0.629 265 2627 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.01 0.883 – 1.16 0.838 260 2584 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 0.956 0.892 – 1.02 0.2 1116 10947 exclusion phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1.08 0.938 – 1.25 0.268 251 2500 exclusion phecode
249 Secondary diabetes mellitus Endocrine/metabolic 0.933 0.794 – 1.09 0.391 215 2144 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 0.983 0.953 – 1.01 0.276 6571 23449 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.02 0.937 – 1.1 0.699 851 8507 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.15 1.06 – 1.21 0.236 59 582 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.11 0.938 – 1.32 0.202 183 1830 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.07 1.01 – 1.16 0.352 201 2010 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 0.994 0.931 – 1.04 0.941 157 1567 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.981 0.947 – 1.02 0.295 4744 22089 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.936 0.902 – 1.01 0.579 59 590 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.948 0.865 – 1.04 0.254 655 6536 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.02 0.947 – 1.09 0.655 459 4564 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.01 0.93 – 1.09 0.823 1001 9978 exclusion phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 0.949 0.897 – 0.997 0.531 140 1384 exclusion phecode
250.3 Insulin pump user Endocrine/metabolic 0.998 0.929 – 1.07 0.949 1048 10475 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 0.984 0.943 – 1.03 0.46 3031 21772 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.99 0.934 – 1.05 0.743 1534 15312 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.987 0.937 – 1.04 0.607 2039 19010 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.01 0.879 – 1.16 0.819 621 6207 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.05 0.92 – 1.2 0.399 403 4019 exclusion phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 0.768 0.542 – 1.07 0.121 57 570 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 0.967 0.861 – 1.08 0.563 395 3937 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.995 0.93 – 1.06 0.876 1146 11426 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.999 0.932 – 1.07 0.976 1057 10545 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.847 0.7 – 1.02 0.0809 159 1590 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.04 0.933 – 1.15 0.485 447 4455 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.09 0.897 – 1.33 0.366 111 1110 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.936 0.755 – 1.15 0.539 116 1160 exclusion phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 1.02 0.975 – 1.09 0.847 74 731 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.957 0.691 – 1.3 0.779 58 580 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.913 0.843 – 0.988 0.0248 833 8330 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.904 0.766 – 1.06 0.227 186 1860 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.895 0.678 – 1.14 0.337 91 910 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.909 0.678 – 1.2 0.506 65 641 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.858 0.747 – 0.983 0.0273 299 2973 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.819 0.708 – 0.945 0.00658 271 2691 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.92 0.829 – 1.02 0.113 443 4430 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.904 0.803 – 1.02 0.0944 326 3260 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 0.927 0.834 – 1.03 0.156 511 5086 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.939 0.843 – 1.04 0.244 493 4908 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 0.95 0.829 – 1.09 0.458 286 2858 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.05 0.986 – 1.12 0.121 1308 13039 exclusion phecode
260.1 Cachexia Endocrine/metabolic 0.954 0.866 – 0.987 0.59 144 1436 exclusion phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.09 0.997 – 1.2 0.0575 613 6108 exclusion phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.04 0.835 – 1.29 0.735 114 1140 exclusion phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.12 0.97 – 1.29 0.119 255 2540 exclusion phecode
260.6 Anorexia Endocrine/metabolic 0.966 0.807 – 1.14 0.556 389 3850 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 0.983 0.945 – 1.02 0.383 3525 24019 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.988 0.867 – 1.12 0.845 358 3580 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.978 0.94 – 1.02 0.273 3313 23242 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.972 0.847 – 1.11 0.682 260 2590 exclusion phecode
263 Other nutritional deficiency Endocrine/metabolic 0.928 0.838 – 1.03 0.149 529 5280 exclusion phecode
264 Lack of normal physiological development Endocrine/metabolic 0.976 0.913 – 1.03 0.816 76 751 exclusion phecode
269 Proteinuria Endocrine/metabolic 0.987 0.905 – 1.07 0.757 735 7213 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.992 0.879 – 1.12 0.892 398 3865 exclusion phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.933 0.865 – 0.972 0.563 61 589 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.01 0.879 – 1.16 0.882 316 3032 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 0.976 0.819 – 1.16 0.781 210 1997 exclusion phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.27 0.978 – 1.65 0.066 73 714 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.849 0.724 – 0.993 0.041 223 2206 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.866 0.729 – 1.02 0.094 193 1909 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.987 0.959 – 1.01 0.345 10265 19513 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.987 0.959 – 1.01 0.349 10251 19507 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.972 0.929 – 1.02 0.224 3043 15630 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.895 0.808 – 0.99 0.0315 519 5180 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.961 0.901 – 1.03 0.235 1332 12131 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.988 0.944 – 1.11 0.891 123 1213 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.997 0.932 – 1.07 0.932 1191 11876 exclusion phecode
274.1 Gout Endocrine/metabolic 0.982 0.915 – 1.05 0.608 1107 11050 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.918 0.811 – 1.04 0.169 372 3715 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.17 0.943 – 1.44 0.15 115 1150 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.21 0.965 – 1.51 0.0934 110 1099 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.966 0.916 – 1.02 0.19 1865 18644 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 1.01 0.811 – 1.25 0.927 108 1080 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 0.882 0.793 – 0.981 0.0209 466 4651 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.967 0.906 – 1.03 0.313 1194 11909 exclusion phecode
275.51 Hypocalcemia Endocrine/metabolic 0.95 0.829 – 1.08 0.449 273 2717 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.955 0.866 – 1.05 0.345 543 5427 exclusion phecode
275.6 Hypercalcemia Endocrine/metabolic 1.04 0.95 – 1.07 0.467 457 4566 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.01 0.978 – 1.05 0.518 5107 25485 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 0.99 0.949 – 1.03 0.643 3192 22522 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.994 0.821 – 1.2 0.941 222 2203 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 0.98 0.915 – 1.05 0.569 1169 11544 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1 0.94 – 1.06 0.992 1433 14011 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 0.994 0.924 – 1.07 0.862 962 9613 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.02 0.948 – 1.09 0.64 1035 10323 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.01 0.94 – 1.09 0.72 881 8786 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 0.963 0.82 – 1.13 0.638 216 2160 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.01 0.969 – 1.06 0.555 2618 23255 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.02 0.939 – 1.12 0.587 711 7088 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 0.842 0.61 – 1.13 0.248 56 560 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 0.995 0.936 – 1.06 0.88 1380 13766 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.958 0.81 – 1.13 0.591 203 2027 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.967 0.877 – 1.06 0.497 554 5531 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.962 0.853 – 1.08 0.521 373 3726 exclusion phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 0.981 0.874 – 1.1 0.736 391 3910 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.986 0.962 – 1.01 0.285 11126 19544 exclusion phecode
278.1 Obesity Endocrine/metabolic 0.989 0.964 – 1.02 0.407 10351 19542 exclusion phecode
278.11 Morbid obesity Endocrine/metabolic 0.978 0.943 – 1.01 0.228 4187 19492 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 0.856 0.737 – 0.99 0.0366 235 2350 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.97 0.902 – 1.04 0.406 940 9274 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.974 0.911 – 1.04 0.445 1208 12073 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 0.961 0.86 – 1.07 0.476 433 4324 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.06 0.886 – 1.27 0.518 171 1700 exclusion phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 0.798 0.589 – 1.03 0.0845 71 710 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 0.979 0.941 – 1.02 0.294 3389 25908 exclusion phecode
280 Iron deficiency anemias Hematopoietic 0.998 0.951 – 1.05 0.933 2307 20801 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.992 0.942 – 1.04 0.754 1978 19091 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.986 0.911 – 1.07 0.732 856 8545 exclusion phecode
281 Other deficiency anemia Hematopoietic 0.99 0.844 – 1.16 0.904 224 2231 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 0.947 0.883 – 1 0.554 108 1058 exclusion phecode
281.11 Pernicious anemia Hematopoietic 0.97 0.792 – 1 0.814 53 530 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.921 0.841 – 0.964 0.513 56 551 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1 0.728 – 1.06 0.967 122 1199 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 0.964 0.895 – 1 0.695 122 1201 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 0.937 0.718 – 0.971 0.558 78 757 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 0.916 0.699 – 1.19 0.512 79 790 exclusion phecode
284 Aplastic anemia Hematopoietic 1.03 0.795 – 1.07 0.682 299 2974 exclusion phecode
284.1 Pancytopenia Hematopoietic 1.02 0.93 – 1.06 0.711 229 2272 exclusion phecode
285 Other anemias Hematopoietic 0.993 0.962 – 1.03 0.678 5785 24163 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1 0.946 – 1.06 0.993 1731 16445 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.01 0.934 – 1.09 0.815 910 9055 exclusion phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.02 0.895 – 1.16 0.759 316 3151 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.03 0.897 – 1.17 0.711 300 2991 exclusion phecode
286 Coagulation defects Hematopoietic 0.975 0.918 – 1.03 0.403 1453 14470 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.904 0.746 – 1.09 0.29 133 1314 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.765 0.725 – 0.801 0.05 51 502 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.08 0.814 – 1.36 0.545 65 634 exclusion phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.01 0.952 – 1.07 0.76 1651 15048 exclusion phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 0.848 0.669 – 1.07 0.164 101 1010 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.987 0.915 – 1.06 0.736 911 9092 exclusion phecode
286.8 Hypercoagulable state Hematopoietic 0.979 0.87 – 1.1 0.722 381 3807 exclusion phecode
286.81 Primary hypercoagulable state Hematopoietic 0.968 0.858 – 1.09 0.598 361 3606 exclusion phecode
286.9 Abnormal coagulation profile Hematopoietic 0.982 0.867 – 1.11 0.774 363 3613 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.975 0.918 – 1.04 0.422 1488 14458 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.88 0.705 – 1.09 0.25 113 1127 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 0.969 0.909 – 1.03 0.322 1377 13471 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.05 0.864 – 1.27 0.625 149 1485 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.845 0.729 – 0.975 0.0221 261 2610 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.03 0.98 – 1.08 0.244 2050 20073 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.02 0.941 – 1.11 0.574 733 7302 exclusion phecode
288.11 Neutropenia Hematopoietic 1.05 0.958 – 1.15 0.283 597 5935 exclusion phecode
288.2 Elevated white blood cell count Hematopoietic 1 0.943 – 1.07 0.914 1366 13627 exclusion phecode
288.3 Eosinophilia Hematopoietic 1.05 0.807 – 1.35 0.725 75 750 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.05 0.96 – 1.15 0.269 614 6102 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.05 0.904 – 1.21 0.538 230 2251 exclusion phecode
289.4 Lymphadenitis Hematopoietic 0.971 0.925 – 1.02 0.234 2439 23341 exclusion phecode
289.5 Diseases of spleen Hematopoietic 0.904 0.779 – 1.05 0.175 258 2580 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.12 0.873 – 1.43 0.365 79 790 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.02 0.85 – 1.21 0.855 169 1686 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.07 0.972 – 1.18 0.165 624 5973 exclusion phecode
290.1 Dementias Mental Disorders 1.03 0.883 – 1.2 0.686 231 2241 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.899 0.866 – 0.954 0.401 60 585 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.09 0.957 – 1.24 0.185 346 3405 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.01 0.907 – 1.12 0.87 456 4548 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.959 0.898 – 1.02 0.21 1207 12031 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.964 0.893 – 1 0.677 141 1410 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 0.967 0.901 – 1.04 0.346 1058 10555 exclusion phecode
292 Neurological disorders Mental Disorders 0.994 0.95 – 1.04 0.778 2702 23616 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.965 0.894 – 1.04 0.361 923 9209 exclusion phecode
292.11 Aphasia Mental Disorders 1.06 0.924 – 1.21 0.406 272 2719 exclusion phecode
292.12 Symbolic dysfunction Mental Disorders 0.885 0.708 – 1.1 0.271 110 1100 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.902 0.668 – 1.17 0.392 107 1047 exclusion phecode
292.3 Memory loss Mental Disorders 0.99 0.892 – 1.1 0.806 793 7884 exclusion phecode
292.4 Altered mental status Mental Disorders 0.992 0.924 – 1.06 0.818 1108 11009 exclusion phecode
292.5 Transient alteration of awareness Mental Disorders 0.749 0.592 – 0.942 0.0138 98 951 exclusion phecode
292.6 Hallucinations Mental Disorders 1.18 0.921 – 1.5 0.183 86 851 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 0.953 0.787 – 1.15 0.619 140 1397 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.946 0.904 – 0.989 0.0152 2758 25622 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.02 0.901 – 1.15 0.771 380 2493 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.02 0.791 – 1.33 0.846 78 483 exclusion phecode
295.3 Psychosis Mental Disorders 1.02 0.887 – 1.17 0.765 290 1913 exclusion phecode
296 Mood disorders Mental Disorders 0.993 0.964 – 1.02 0.653 7043 19850 exclusion phecode
296.1 Bipolar Mental Disorders 0.97 0.9 – 1.05 0.431 886 5627 exclusion phecode
296.2 Depression Mental Disorders 0.995 0.965 – 1.03 0.732 6651 19846 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.01 0.955 – 1.07 0.718 1586 10368 exclusion phecode
297 Suicidal ideation or attempt Mental Disorders 0.936 0.794 – 1.08 0.233 380 2480 exclusion phecode
297.1 Suicidal ideation Mental Disorders 0.959 0.779 – 0.995 0.488 313 2013 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.831 0.678 – 1.01 0.0674 122 772 exclusion phecode
300 Anxiety disorders Mental Disorders 0.979 0.95 – 1.01 0.176 6782 19893 exclusion phecode
300.1 Anxiety disorder Mental Disorders 0.982 0.952 – 1.01 0.264 6337 19891 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 0.954 0.89 – 1.02 0.175 1096 7023 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.07 0.973 – 1.17 0.167 566 3553 exclusion phecode
300.13 Phobia Mental Disorders 1.09 0.901 – 1.32 0.368 141 907 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.938 0.867 – 0.981 0.485 113 689 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 0.943 0.873 – 1.02 0.13 914 5746 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 0.978 0.845 – 1.13 0.762 242 1461 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.966 0.855 – 1.09 0.573 326 2014 exclusion phecode
301 Personality disorders Mental Disorders 1.06 0.71 – 1.1 0.373 209 1257 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.998 0.811 – 1.22 0.979 140 838 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 0.978 0.866 – 1.1 0.71 377 2508 exclusion phecode
302.1 Decreased libido Mental Disorders 1.06 0.884 – 1.28 0.506 152 961 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.996 0.901 – 1.1 0.941 505 3183 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.968 0.841 – 1.11 0.651 267 1630 exclusion phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 1.01 0.822 – 1.24 0.927 131 825 exclusion phecode
303.4 Somatoform disorder Mental Disorders 1.01 0.886 – 1.16 0.843 262 1602 exclusion phecode
304 Adjustment reaction Mental Disorders 0.964 0.913 – 1.02 0.184 1826 12239 exclusion phecode
305.2 Eating disorder Mental Disorders 0.862 0.751 – 0.989 0.0349 268 1623 exclusion phecode
306 Other mental disorder Mental Disorders 1.01 0.904 – 1.12 0.913 432 2687 exclusion phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 0.973 0.905 – 1 0.699 202 1163 exclusion phecode
306.9 Tension headache Mental Disorders 1.01 0.838 – 1.21 0.922 144 869 exclusion phecode
312 Conduct disorders Mental Disorders 0.885 0.684 – 1.11 0.277 88 872 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.999 0.91 – 1.1 0.979 534 5301 exclusion phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1.02 0.835 – 1.06 0.628 446 4428 exclusion phecode
315 Develomental delays and disorders Mental Disorders 0.998 0.858 – 1.16 0.981 219 2183 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.03 0.97 – 1.08 0.368 1510 15048 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.14 1.01 – 1.29 0.036 332 3306 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.05 0.989 – 1.12 0.105 1226 12156 exclusion phecode
317.1 Alcoholism Mental Disorders 1.06 0.982 – 1.14 0.135 880 8722 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 0.956 0.744 – 0.99 0.5 246 2450 exclusion phecode
318 Tobacco use disorder Mental Disorders 0.999 0.969 – 1.03 0.922 7065 22379 exclusion phecode
320 Meningitis Neurological 1.02 0.851 – 1.21 0.853 169 1690 exclusion phecode
323 Encephalitis Neurological 0.823 0.631 – 1.06 0.133 87 870 exclusion phecode
323.8 Encephalitis, non-infectious Neurological 0.815 0.613 – 1.07 0.144 69 690 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 0.951 0.859 – 1 0.579 147 1460 exclusion phecode
327 Sleep disorders Neurological 0.99 0.96 – 1.02 0.546 6050 23068 exclusion phecode
327.1 Hypersomnia Neurological 0.918 0.817 – 1.03 0.146 378 3756 exclusion phecode
327.3 Sleep apnea Neurological 0.987 0.956 – 1.02 0.443 5492 22522 exclusion phecode
327.31 Central/nonobstroctive sleep apnea Neurological 1.13 1.05 – 1.17 0.283 70 700 exclusion phecode
327.32 Obstructive sleep apnea Neurological 1.01 0.969 – 1.05 0.711 3525 21245 exclusion phecode
327.4 Insomnia Neurological 1.01 0.964 – 1.05 0.782 2779 22130 exclusion phecode
327.41 Organic or persistent insomnia Neurological 0.987 0.915 – 1.06 0.739 900 8999 exclusion phecode
327.5 Parasomnia Neurological 0.98 0.858 – 1.12 0.759 296 2958 exclusion phecode
327.6 Circadian rhythm sleep disorder Neurological 0.975 0.786 – 1.21 0.815 104 1033 exclusion phecode
327.7 Sleep related movement disorders Neurological 1.01 0.921 – 1.1 0.885 629 6290 exclusion phecode
327.71 Restless legs syndrome Neurological 1.03 0.937 – 1.13 0.563 573 5730 exclusion phecode
331 Other cerebral degenerations Neurological 0.91 0.822 – 1.01 0.0646 573 5621 exclusion phecode
331.1 Hydrocephalus Neurological 0.919 0.779 – 1.08 0.308 176 1750 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 0.845 0.731 – 0.973 0.0204 318 3071 exclusion phecode
332 Parkinson's disease Neurological 1.02 0.876 – 1.18 0.827 234 2320 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.02 0.951 – 1.09 0.583 1052 10510 exclusion phecode
333.1 Essential tremor Neurological 0.926 0.816 – 1.05 0.224 360 3596 exclusion phecode
333.2 Myoclonus Neurological 0.992 0.931 – 1.03 0.947 67 660 exclusion phecode
333.4 Torsion dystonia Neurological 1.1 0.923 – 1.3 0.284 161 1610 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 0.918 0.823 – 1.02 0.0811 541 5404 exclusion phecode
334.2 Anterior horn cell disease Neurological 0.91 0.867 – 1.24 0.492 65 650 exclusion phecode
335 Multiple sclerosis Neurological 0.92 0.794 – 1.06 0.258 234 2340 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.02 0.873 – 1.18 0.82 227 2270 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.01 0.951 – 1.04 0.954 94 921 exclusion phecode
338 Pain Neurological 1 0.97 – 1.03 0.993 6219 24423 exclusion phecode
338.1 Acute pain Neurological 0.999 0.965 – 1.03 0.94 4436 24130 exclusion phecode
338.2 Chronic pain Neurological 1 0.957 – 1.05 0.99 2538 21419 exclusion phecode
339 Other headache syndromes Neurological 0.969 0.935 – 1 0.076 4406 24884 exclusion phecode
340 Migraine Neurological 0.957 0.913 – 1 0.0604 2362 16920 exclusion phecode
340.1 Migrain with aura Neurological 0.973 0.855 – 1.1 0.54 573 5700 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.968 0.828 – 1.01 0.797 63 630 exclusion phecode
342 Hemiplegia Neurological 0.861 0.733 – 1.01 0.0616 235 2349 exclusion phecode
343 Infantile cerebral palsy Neurological 1.04 0.961 – 1.1 0.769 54 534 exclusion phecode
344 Other paralytic syndromes Neurological 0.995 0.88 – 1.12 0.931 352 3520 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.982 0.918 – 1.05 0.589 1102 11005 exclusion phecode
345.1 Epilepsy Neurological 0.9 0.802 – 1.01 0.0715 382 3812 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 0.891 0.618 – 0.932 0.26 99 990 exclusion phecode
345.12 Partial epilepsy Neurological 0.91 0.864 – 0.958 0.15 257 2565 exclusion phecode
345.3 Convulsions Neurological 0.976 0.904 – 1.05 0.52 876 8735 exclusion phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 1.19 0.884 – 1.61 0.235 67 660 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.02 0.943 – 1.1 0.613 873 8722 exclusion phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 0.808 0.62 – 1.04 0.102 75 741 exclusion phecode
348 Other conditions of brain Neurological 0.957 0.889 – 1.03 0.23 1013 10105 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 0.967 0.873 – 1.07 0.515 505 5050 exclusion phecode
348.4 Cerebral cysts Neurological 0.898 0.74 – 1.09 0.267 147 1463 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 0.937 0.839 – 1.05 0.245 456 4553 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 0.982 0.925 – 1.04 0.554 1552 15496 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.935 0.846 – 1.03 0.182 520 5191 exclusion phecode
350 Abnormal movement Neurological 0.999 0.957 – 1.04 0.95 2950 25091 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1 0.945 – 1.07 0.888 1427 14243 exclusion phecode
350.2 Abnormality of gait Neurological 0.972 0.919 – 1.03 0.328 1707 16093 exclusion phecode
350.3 Lack of coordination Neurological 0.943 0.83 – 1.07 0.358 330 3300 exclusion phecode
350.5 Abnormal reflex Neurological 0.963 0.659 – 1.35 0.78 58 573 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.969 0.922 – 1.01 0.644 207 2060 exclusion phecode
351 Other peripheral nerve disorders Neurological 0.99 0.953 – 1.03 0.624 3518 25379 exclusion phecode
352 Disorders of other cranial nerves Neurological 0.985 0.91 – 1.06 0.698 901 9006 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.899 0.782 – 1.03 0.131 282 2816 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 0.992 0.881 – 1.12 0.897 423 4227 exclusion phecode
353 Nerve root and plexus disorders Neurological 0.972 0.865 – 1.09 0.631 355 3531 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.981 0.886 – 1.02 0.794 179 1790 exclusion phecode
355 Complex regional/central pain syndrome Neurological 1.13 0.974 – 1.3 0.102 226 2260 exclusion phecode
355.1 Chronic pain syndrome Neurological 0.987 0.834 – 1.16 0.88 165 1650 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.998 0.932 – 1.07 0.966 1175 11652 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 0.971 0.898 – 1.05 0.459 906 9030 exclusion phecode
358 Myoneural disorders Neurological 0.937 0.752 – 1.16 0.552 101 1007 exclusion phecode
358.1 Myasthenia gravis Neurological 1.04 0.983 – 1.07 0.727 57 564 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.955 0.838 – 1.09 0.486 306 3043 exclusion phecode
359.2 Myopathy Neurological 0.945 0.825 – 1.08 0.408 283 2813 exclusion phecode
360 Disorders of the globe Sense Organs 0.833 0.444 – 0.868 0.171 78 771 exclusion phecode
361 Retinal detachments and defects Sense Organs 1.04 0.895 – 1.21 0.565 291 2908 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.06 0.923 – 1.1 0.5 132 1307 exclusion phecode
362 Other retinal disorders Sense Organs 0.97 0.91 – 1.03 0.335 1506 13094 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.951 0.875 – 1.03 0.229 910 8102 exclusion phecode
362.21 Macular degeneration, dry Sense Organs 0.962 0.913 – 0.996 0.568 214 1906 exclusion phecode
362.22 Macular degeneration, wet Sense Organs 0.929 0.808 – 0.955 0.458 77 638 exclusion phecode
362.23 Cystoid macular degeneration of retina Sense Organs 0.907 0.855 – 0.969 0.294 141 1390 exclusion phecode
362.26 Macular puckering of retina Sense Organs 0.906 0.777 – 1.04 0.134 340 3337 exclusion phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.847 0.689 – 1.01 0.0541 213 2089 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.95 0.861 – 0.985 0.373 362 3218 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.947 0.873 – 0.997 0.397 283 2806 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1 0.786 – 1.05 0.951 293 2899 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.945 0.904 – 0.999 0.498 155 1541 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.791 0.563 – 1.1 0.161 63 626 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.03 0.994 – 1.11 0.717 100 996 exclusion phecode
362.9 Retinal edema Sense Organs 0.811 0.773 – 0.854 0.038 121 1201 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1 0.854 – 1.17 0.974 219 2166 exclusion phecode
363.3 Chorioretinal scars Sense Organs 1.06 0.983 – 1.12 0.467 154 1524 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.935 0.844 – 1.04 0.197 538 5323 exclusion phecode
364.1 Corneal opacity Sense Organs 0.883 0.749 – 1.04 0.13 202 2013 exclusion phecode
364.2 Corneal edema Sense Organs 0.822 0.574 – 1.15 0.256 52 515 exclusion phecode
364.4 Corneal degenerations Sense Organs 0.828 0.682 – 1 0.0519 161 1600 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.952 0.664 – 0.989 0.437 284 2796 exclusion phecode
364.51 Fuchs' dystrophy Sense Organs 0.99 0.889 – 1.02 0.894 131 1300 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.904 0.837 – 0.976 0.448 55 541 exclusion phecode
365 Glaucoma Sense Organs 0.986 0.919 – 1.06 0.707 1106 10654 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 1.01 0.949 – 1.04 0.921 342 3328 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.939 0.892 – 0.972 0.384 207 2006 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.01 0.907 – 1.05 0.913 109 1055 exclusion phecode
366 Cataract Sense Organs 0.975 0.935 – 1.02 0.23 3689 19186 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 0.975 0.788 – 1.2 0.815 135 1332 exclusion phecode
366.2 Senile cataract Sense Organs 0.964 0.918 – 1.01 0.145 2616 16782 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.963 0.93 – 0.997 0.0342 4681 25934 exclusion phecode
367.1 Myopia Sense Organs 0.976 0.934 – 1.02 0.278 2752 22991 exclusion phecode
367.2 Astigmatism Sense Organs 1.01 0.948 – 1.06 0.863 1527 15060 exclusion phecode
367.4 Presbyopia Sense Organs 0.993 0.945 – 1.04 0.79 2222 19016 exclusion phecode
367.8 Hypermetropia Sense Organs 0.915 0.853 – 0.981 0.0127 1149 11387 exclusion phecode
367.9 Blindness and low vision Sense Organs 1 0.875 – 1.15 0.977 400 3992 exclusion phecode
368 Visual disturbances Sense Organs 0.977 0.932 – 1.03 0.35 2272 22272 exclusion phecode
368.1 Amblyopia Sense Organs 0.921 0.852 – 0.962 0.335 152 1504 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.956 0.867 – 1.05 0.366 562 5610 exclusion phecode
368.3 Anisometropia Sense Organs 0.872 0.704 – 1.07 0.199 124 1222 exclusion phecode
368.4 Visual field defects Sense Organs 0.971 0.877 – 1.07 0.562 532 5315 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.962 0.874 – 1.06 0.421 573 5704 exclusion phecode
369 Infection of the eye Sense Organs 0.967 0.913 – 1.02 0.251 1559 15432 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.885 0.757 – 1.03 0.118 227 2240 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.951 0.893 – 1.01 0.11 1317 13136 exclusion phecode
370 Keratitis Sense Organs 0.948 0.866 – 1.04 0.245 711 6972 exclusion phecode
370.1 Corneal ulcer Sense Organs 1.11 0.867 – 1.42 0.398 90 890 exclusion phecode
370.2 Superficial keratitis Sense Organs 0.976 0.834 – 1.14 0.757 249 2474 exclusion phecode
370.3 Keratoconjunctivitis Sense Organs 0.9 0.793 – 1.02 0.095 387 3780 exclusion phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.918 0.827 – 0.966 0.401 124 1194 exclusion phecode
371 Inflammation of the eye Sense Organs 0.977 0.927 – 1.03 0.372 2106 18893 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.792 0.684 – 0.914 0.00153 292 2902 exclusion phecode
371.2 Conjunctivitis, noninfectious Sense Organs 1.16 1.04 – 1.3 0.00748 392 3893 exclusion phecode
371.21 Allergic conjunctivitis Sense Organs 1.16 1.02 – 1.32 0.0226 293 2898 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.977 0.919 – 1.04 0.445 1606 15153 exclusion phecode
372 Disorders of conjunctiva Sense Organs 0.981 0.883 – 1.09 0.726 523 5153 exclusion phecode
374 Other disorders of eyelids Sense Organs 0.985 0.919 – 1.05 0.662 1302 12613 exclusion phecode
374.1 Ectropion or entropion Sense Organs 1.01 0.829 – 1.24 0.886 194 1910 exclusion phecode
374.2 Lagophthalmos Sense Organs 0.917 0.719 – 1.16 0.471 123 1229 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.924 0.829 – 1.03 0.153 504 5016 exclusion phecode
374.6 Dermatochalasis Sense Organs 0.937 0.893 – 1.1 0.247 469 4650 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.958 0.814 – 1.12 0.596 235 2341 exclusion phecode
375.1 Dry eyes Sense Organs 0.968 0.913 – 1.03 0.269 1711 14550 exclusion phecode
375.2 Epiphora Sense Organs 0.948 0.795 – 1.13 0.55 200 1999 exclusion phecode
376 Disorders of the orbit Sense Organs 1 0.931 – 1.03 0.99 102 1020 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.966 0.859 – 1.08 0.555 400 3948 exclusion phecode
377.1 Optic atrophy Sense Organs 0.924 0.878 – 0.977 0.418 117 1170 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.849 0.726 – 0.989 0.0358 230 2283 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.922 0.845 – 1.01 0.0665 694 6883 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.889 0.796 – 0.991 0.0345 442 4389 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.05 0.845 – 1.31 0.639 100 987 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.02 0.864 – 1.19 0.848 207 2060 exclusion phecode
379 Other disorders of eye Sense Organs 0.993 0.942 – 1.05 0.794 2085 17093 exclusion phecode
379.1 Scleritis and episcleritis Sense Organs 1.14 0.904 – 1.44 0.25 90 894 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.987 0.927 – 1.05 0.69 1519 12947 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.886 0.848 – 1.02 0.3 86 846 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 0.99 0.927 – 1.03 0.901 152 1515 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.983 0.801 – 1.2 0.868 129 1281 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.93 0.843 – 1.02 0.142 556 5528 exclusion phecode
380 Disorders of external ear Sense Organs 1.03 0.834 – 1.26 0.795 151 1508 exclusion phecode
380.1 Otitis externa Sense Organs 0.905 0.832 – 0.984 0.0194 741 7380 exclusion phecode
380.4 Impacted cerumen Sense Organs 0.927 0.871 – 0.987 0.0178 1499 14330 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.969 0.923 – 1.02 0.21 2133 20765 exclusion phecode
381.1 Otitis media Sense Organs 0.969 0.915 – 1.03 0.294 1476 14637 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.955 0.896 – 1.02 0.15 1250 12480 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.965 0.896 – 1.04 0.336 971 9677 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 0.87 0.826 – 1.16 0.306 64 640 exclusion phecode
381.9 Otorrhea Sense Organs 1.13 0.941 – 1.36 0.182 159 1574 exclusion phecode
382 Otalgia Sense Organs 1.01 0.933 – 1.08 0.883 903 9000 exclusion phecode
383 Otosclerosis Sense Organs 0.894 0.705 – 1.13 0.343 89 890 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.11 0.958 – 1.28 0.161 221 2203 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.14 0.976 – 1.33 0.0919 187 1856 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.964 0.838 – 1.11 0.601 235 2350 exclusion phecode
385.3 Cholesteatoma Sense Organs 0.918 0.777 – 1.08 0.309 176 1760 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.02 0.791 – 1.29 0.885 71 710 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.01 0.937 – 1.09 0.776 915 9099 exclusion phecode
386.1 Meniere's disease Sense Organs 1.07 0.792 – 1.13 0.49 119 1171 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.974 0.892 – 1.06 0.548 694 6896 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.11 0.856 – 1.18 0.149 171 1694 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.982 0.945 – 1.02 0.374 3609 25786 exclusion phecode
388 Other disorders of ear Sense Organs 0.974 0.852 – 1.11 0.69 315 3140 exclusion phecode
389 Hearing loss Sense Organs 0.974 0.937 – 1.01 0.188 3708 25750 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.983 0.934 – 1.03 0.506 2178 19347 exclusion phecode
389.2 Conductive hearing loss Sense Organs 0.956 0.866 – 1.05 0.369 515 5142 exclusion phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.925 0.874 – 0.966 0.518 69 680 exclusion phecode
389.4 Tinnitus Sense Organs 1.03 0.949 – 1.11 0.508 889 8870 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 0.993 0.929 – 1.06 0.826 1216 11503 exclusion phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 0.899 0.761 – 1.06 0.201 216 2134 exclusion phecode
394.2 Mitral valve disease Circulatory System 0.985 0.893 – 1.09 0.771 556 5510 exclusion phecode
394.3 Aortic valve disease Circulatory System 0.961 0.855 – 1.08 0.497 413 3996 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.07 0.945 – 1.21 0.284 328 3256 exclusion phecode
395 Heart valve disorders Circulatory System 0.987 0.937 – 1.04 0.64 1981 17661 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.988 0.921 – 1.06 0.729 1107 10905 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.99 0.916 – 1.07 0.8 945 9002 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 0.912 0.784 – 1.06 0.22 256 2540 exclusion phecode
395.6 Heart valve replaced Circulatory System 0.973 0.885 – 1.07 0.562 629 6079 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.01 0.946 – 1.08 0.735 1215 12054 exclusion phecode
401 Hypertension Circulatory System 0.989 0.962 – 1.02 0.441 13126 17239 exclusion phecode
401.1 Essential hypertension Circulatory System 0.987 0.961 – 1.02 0.369 12947 17239 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1 0.944 – 1.06 0.962 1700 10273 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.02 0.955 – 1.09 0.807 158 1524 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.01 0.947 – 1.07 0.819 1535 9797 exclusion phecode
401.3 Other hypertensive complications Circulatory System 0.984 0.918 – 1.05 0.651 1148 9924 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 0.969 0.909 – 1.03 0.33 1331 12405 exclusion phecode
411 Ischemic Heart Disease Circulatory System 0.989 0.954 – 1.03 0.571 4915 20312 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.935 0.836 – 1.04 0.234 450 4414 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.02 0.966 – 1.08 0.438 1702 12837 exclusion phecode
411.3 Angina pectoris Circulatory System 0.952 0.872 – 1.04 0.262 737 7089 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 0.989 0.951 – 1.03 0.558 4396 19028 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.984 0.832 – 1.16 0.853 197 1953 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.02 0.935 – 1.1 0.706 823 7474 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.07 0.921 – 1.23 0.385 244 2387 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.01 0.946 – 1.08 0.729 1152 10966 exclusion phecode
414.2 ASCVD Circulatory System 1.07 0.911 – 1.26 0.395 217 2132 exclusion phecode
415 Pulmonary heart disease Circulatory System 0.995 0.941 – 1.05 0.859 1683 16616 exclusion phecode
415.1 Acute pulmonary heart disease Circulatory System 1.04 0.954 – 1.13 0.374 712 7112 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.04 0.956 – 1.14 0.346 708 7070 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1 0.929 – 1.08 0.916 884 8815 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.02 0.9 – 1.15 0.783 342 3403 exclusion phecode
416 Cardiomegaly Circulatory System 0.955 0.868 – 1.05 0.346 593 5897 exclusion phecode
418 Nonspecific chest pain Circulatory System 0.985 0.957 – 1.01 0.33 7097 23491 exclusion phecode
418.1 Precordial pain Circulatory System 0.99 0.919 – 1.07 0.788 987 9853 exclusion phecode
420 Carditis Circulatory System 0.951 0.874 – 1.03 0.245 754 7518 exclusion phecode
420.2 Pericarditis Circulatory System 0.956 0.858 – 1.06 0.403 481 4804 exclusion phecode
420.21 Acute pericarditis Circulatory System 0.943 0.854 – 0.986 0.567 87 861 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.09 0.82 – 1.44 0.533 62 620 exclusion phecode
420.3 Endocarditis Circulatory System 1.01 0.852 – 1.19 0.923 267 2650 exclusion phecode
425 Cardiomyopathy Circulatory System 1.06 0.986 – 1.13 0.117 1096 10739 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.05 0.98 – 1.13 0.162 1066 10448 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.15 0.945 – 1.4 0.153 128 1266 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.04 0.819 – 1.32 0.728 90 900 exclusion phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.15 0.931 – 1.42 0.187 124 1237 exclusion phecode
426 Cardiac conduction disorders Circulatory System 0.987 0.956 – 1.02 0.43 7210 17839 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 0.969 0.901 – 1.04 0.402 1143 7891 exclusion phecode
426.21 First degree AV block Circulatory System 0.932 0.855 – 1.01 0.104 832 6368 exclusion phecode
426.23 Second degree AV block Circulatory System 0.965 0.851 – 1.01 0.725 97 898 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 0.928 0.795 – 1.08 0.336 242 2120 exclusion phecode
426.25 Other heart block Circulatory System 0.929 0.736 – 1.16 0.506 121 1098 exclusion phecode
426.3 Bundle branch block Circulatory System 0.977 0.912 – 1.05 0.503 1226 9124 exclusion phecode
426.31 Right bundle branch block Circulatory System 0.966 0.887 – 1.05 0.418 812 7016 exclusion phecode
426.32 Left bundle branch block Circulatory System 0.969 0.866 – 1.08 0.573 438 4157 exclusion phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 0.985 0.952 – 1.02 0.38 6081 17672 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 0.966 0.82 – 1.13 0.672 192 1913 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.987 0.904 – 1.08 0.766 745 6035 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.968 0.872 – 1.07 0.547 533 4363 exclusion phecode
426.92 Cardiac defibrillator in situ Circulatory System 0.976 0.859 – 1.11 0.711 331 3178 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 0.995 0.969 – 1.02 0.745 10192 18017 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1 0.934 – 1.08 0.914 1046 9517 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.01 0.917 – 1.11 0.862 585 5772 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.986 0.793 – 1.04 0.765 543 5165 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1 0.955 – 1.05 0.95 2919 12586 exclusion phecode
427.21 Atrial fibrillation Circulatory System 0.981 0.93 – 1.04 0.489 2217 11443 exclusion phecode
427.22 Atrial flutter Circulatory System 1.06 0.96 – 1.17 0.25 587 5395 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.982 0.948 – 1.02 0.289 5582 18019 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.02 0.877 – 1.18 0.83 261 2559 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.91 0.706 – 1.16 0.449 97 969 exclusion phecode
427.42 Cardiac arrest Circulatory System 0.989 0.837 – 1.17 0.896 203 2000 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.979 0.937 – 1.02 0.352 2897 17415 exclusion phecode
427.6 Premature beats Circulatory System 0.974 0.907 – 1.05 0.463 1161 9505 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 0.985 0.836 – 1.15 0.805 357 3397 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.03 0.982 – 1.07 0.245 2772 17929 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.968 0.873 – 1.07 0.529 565 5082 exclusion phecode
427.9 Palpitations Circulatory System 0.974 0.93 – 1.02 0.278 2480 16718 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.03 0.975 – 1.08 0.305 2011 15882 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.04 0.982 – 1.11 0.172 1548 13804 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.04 0.967 – 1.12 0.295 1033 9643 exclusion phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.12 1.01 – 1.25 0.0328 477 4733 exclusion phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 0.999 0.889 – 1.12 0.981 418 4122 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 0.983 0.944 – 1.02 0.389 3650 22491 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 0.97 0.866 – 1.09 0.604 421 4183 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.961 0.913 – 1.01 0.129 2116 17256 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.02 0.963 – 1.07 0.536 1836 16273 exclusion phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 0.813 0.706 – 0.933 0.00339 311 3074 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.02 0.914 – 1.14 0.697 423 4215 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.01 0.851 – 1.19 0.925 181 1808 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.06 0.909 – 1.24 0.441 223 2215 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.12 0.909 – 1.39 0.274 122 1211 exclusion phecode
433 Cerebrovascular disease Circulatory System 0.967 0.925 – 1.01 0.144 2858 20352 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.01 0.935 – 1.08 0.846 1049 9556 exclusion phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.12 0.892 – 1.39 0.328 103 1024 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 0.864 0.791 – 1.24 0.358 52 511 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.962 0.881 – 1.05 0.375 727 7183 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.964 0.874 – 1.06 0.459 579 5745 exclusion phecode
433.3 Cerebral ischemia Circulatory System 0.963 0.902 – 1.03 0.247 1366 12552 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 0.972 0.906 – 1.04 0.424 1127 10698 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 0.935 0.824 – 1.06 0.295 310 3081 exclusion phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.05 0.931 – 1.19 0.406 346 3448 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.05 0.926 – 1.2 0.414 329 3275 exclusion phecode
440 Atherosclerosis Circulatory System 0.979 0.922 – 1.04 0.499 1493 13489 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.23 0.997 – 1.29 0.0362 125 1240 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.992 0.916 – 1.07 0.836 862 8502 exclusion phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 0.967 0.866 – 1 0.715 107 1056 exclusion phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 0.979 0.892 – 1.07 0.653 626 6223 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.01 0.782 – 1.05 0.842 574 5624 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 0.942 0.823 – 1.07 0.378 282 2798 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.09 0.915 – 1.32 0.314 148 1470 exclusion phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 0.947 0.713 – 1.23 0.637 92 902 exclusion phecode
442 Other aneurysm Circulatory System 1.02 0.967 – 1.08 0.421 1637 13881 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.03 0.96 – 1.1 0.446 1234 10807 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.03 0.943 – 1.13 0.495 682 6454 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.09 0.78 – 1.14 0.335 137 1369 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.07 0.95 – 1.12 0.443 117 1161 exclusion phecode
442.4 Arterial dissection Circulatory System 1.03 0.983 – 1.07 0.737 98 980 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.03 0.885 – 1.21 0.636 252 2513 exclusion phecode
443 Peripheral vascular disease Circulatory System 0.96 0.905 – 1.02 0.169 1561 14577 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.05 0.929 – 1.18 0.444 347 3470 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.949 0.901 – 1.02 0.417 220 2176 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 0.941 0.767 – 1.15 0.546 124 1234 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.953 0.889 – 1.02 0.169 1120 10522 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 0.968 0.871 – 1.07 0.535 458 4530 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1 0.914 – 1.04 0.953 165 1635 exclusion phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 1.07 0.835 – 1.37 0.575 86 851 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 0.959 0.826 – 1.11 0.573 248 2464 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 0.916 0.836 – 0.947 0.499 59 582 exclusion phecode
446.9 Arteritis NOS Circulatory System 0.935 0.776 – 1.12 0.47 151 1506 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.03 0.956 – 1.1 0.472 1074 10638 exclusion phecode
447.1 Stricture of artery Circulatory System 1.01 0.889 – 1.15 0.853 301 2968 exclusion phecode
447.7 Aortic ectasia Circulatory System 1 0.947 – 1.08 0.957 246 2452 exclusion phecode
448 Disease of capillaries Circulatory System 1.04 0.964 – 1.1 0.672 103 1023 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.01 0.937 – 1.09 0.804 1088 10867 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.05 0.805 – 1.09 0.4 365 3617 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.06 0.869 – 1.3 0.535 120 1198 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 0.973 0.924 – 1.02 0.293 2038 17308 exclusion phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1.11 0.875 – 1.39 0.385 97 970 exclusion phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 0.971 0.905 – 1.04 0.411 1049 10478 exclusion phecode
453 Chronic venous hypertension Circulatory System 1.03 0.75 – 1.1 0.804 88 869 exclusion phecode
454 Varicose veins Circulatory System 1.02 0.953 – 1.08 0.643 1295 12776 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1.02 0.935 – 1.11 0.636 1047 10355 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.02 0.936 – 1.11 0.653 714 7102 exclusion phecode
455 Hemorrhoids Circulatory System 0.977 0.933 – 1.02 0.325 2672 18295 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1 0.943 – 1.06 0.957 1441 13888 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.988 0.954 – 1.02 0.48 5130 20995 exclusion phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 0.871 0.744 – 1.02 0.0808 238 2356 exclusion phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 0.985 0.931 – 1.04 0.599 1843 13035 exclusion phecode
458 Hypotension Circulatory System 0.988 0.947 – 1.03 0.585 3015 22648 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1 0.92 – 1.09 0.936 709 7023 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.09 0.988 – 1.2 0.0857 558 5562 exclusion phecode
458.9 Hypotension NOS Circulatory System 0.978 0.931 – 1.03 0.377 2283 19889 exclusion phecode
459 Other disorders of circulatory system Circulatory System 0.96 0.914 – 1.01 0.107 2161 19021 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 0.936 0.82 – 1.07 0.319 304 3028 exclusion phecode
459.7 Blood vessel replaced Circulatory System 0.988 0.803 – 1.21 0.91 123 1217 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 0.947 0.895 – 1 0.0639 1634 14997 exclusion phecode
464 Acute sinusitis Respiratory 0.968 0.928 – 1.01 0.144 2849 21183 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.978 0.947 – 1.01 0.179 5573 24342 exclusion phecode
465.2 Acute pharyngitis Respiratory 0.982 0.942 – 1.02 0.398 2925 20678 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.01 0.877 – 1.16 0.884 245 2450 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.952 0.858 – 1.05 0.173 939 9346 exclusion phecode
471 Nasal polyps Respiratory 0.882 0.777 – 1 0.0509 324 3206 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.957 0.889 – 1.03 0.231 966 9545 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 0.963 0.909 – 1.02 0.199 1542 15343 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.999 0.867 – 1.15 0.98 358 3569 exclusion phecode
473.4 Voice disturbance Respiratory 0.981 0.919 – 1.05 0.567 1200 11979 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 0.986 0.897 – 1.08 0.777 509 4696 exclusion phecode
474.1 Acute tonsillitis Respiratory 1 0.934 – 1.05 0.96 184 1764 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.01 0.804 – 1.06 0.815 412 3832 exclusion phecode
475 Chronic sinusitis Respiratory 0.965 0.918 – 1.01 0.148 2146 19495 exclusion phecode
475.9 Postnasal drip Respiratory 0.97 0.765 – 1.01 0.657 274 2722 exclusion phecode
476 Allergic rhinitis Respiratory 0.973 0.936 – 1.01 0.152 3745 22635 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 0.981 0.892 – 1.08 0.688 600 5948 exclusion phecode
478 Throat pain Respiratory 0.894 0.751 – 1.06 0.202 186 1852 exclusion phecode
479 Other upper respiratory disease Respiratory 0.992 0.951 – 1.03 0.71 2967 22638 exclusion phecode
480 Pneumonia Respiratory 1.01 0.971 – 1.06 0.567 3008 24384 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.02 0.923 – 1.13 0.675 524 5213 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 0.993 0.791 – 1.24 0.953 102 1017 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 0.927 0.894 – 0.967 0.473 89 887 exclusion phecode
480.2 Viral pneumonia Respiratory 1.25 0.946 – 1.64 0.108 81 801 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.02 0.976 – 1.07 0.884 61 610 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1 0.826 – 1.21 0.987 131 1300 exclusion phecode
481 Influenza Respiratory 0.972 0.889 – 1.06 0.541 654 6500 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.984 0.937 – 1.03 0.53 2148 20399 exclusion phecode
495 Asthma Respiratory 1.01 0.974 – 1.05 0.508 3166 22745 exclusion phecode
495.1 Chronic obstructive asthma Respiratory 1.02 0.889 – 1.16 0.824 304 3023 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.09 1 – 1.19 0.0369 650 6488 exclusion phecode
496 Chronic airway obstruction Respiratory 0.981 0.939 – 1.02 0.379 2968 19630 exclusion phecode
496.1 Emphysema Respiratory 1.01 0.945 – 1.07 0.859 1415 13515 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.03 0.954 – 1.12 0.431 863 8597 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.03 0.94 – 1.14 0.495 603 6024 exclusion phecode
496.3 Bronchiectasis Respiratory 0.924 0.758 – 1.1 0.242 308 3063 exclusion phecode
497 Bronchitis Respiratory 1.01 0.939 – 1.09 0.764 929 9246 exclusion phecode
498 Acute bronchospasm Respiratory 0.921 0.781 – 1.08 0.319 177 1767 exclusion phecode
499 Cystic fibrosis Respiratory 1.06 0.849 – 1.31 0.601 103 1030 exclusion phecode
500 Lung disease due to external agents Respiratory 1.07 0.916 – 1.24 0.405 230 2286 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.06 0.798 – 1.39 0.686 67 670 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.11 0.972 – 1.26 0.124 343 3363 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.809 0.721 – 0.906 0.000251 460 4593 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.03 0.943 – 1.12 0.519 689 6829 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.908 0.798 – 1.03 0.138 326 3248 exclusion phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 0.951 0.809 – 1.11 0.536 208 2063 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 0.924 0.857 – 0.995 0.0361 979 9753 exclusion phecode
506 Empyema and pneumothorax Respiratory 0.962 0.919 – 1.01 0.0969 2507 20090 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 0.948 0.899 – 1 0.0494 1912 17596 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.942 0.888 – 1 0.0493 1534 15115 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 0.981 0.934 – 1.03 0.459 2166 18346 exclusion phecode
509.1 Respiratory failure Respiratory 0.988 0.916 – 1.06 0.746 900 8982 exclusion phecode
509.2 Respiratory insufficiency Respiratory 0.991 0.897 – 1.09 0.861 530 5292 exclusion phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 0.968 0.903 – 1.04 0.347 1135 11297 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.992 0.907 – 1.08 0.852 647 6470 exclusion phecode
510 Other diseases of lung Respiratory 0.959 0.923 – 0.997 0.0365 3872 24663 exclusion phecode
510.2 Lung transplant Respiratory 0.909 0.719 – 1.14 0.411 105 1050 exclusion phecode
512 Other symptoms of respiratory system Respiratory 0.981 0.956 – 1.01 0.153 10908 19791 exclusion phecode
512.1 Wheezing Respiratory 1.04 0.928 – 1.17 0.382 685 6775 exclusion phecode
512.2 Painful respiration Respiratory 0.929 0.858 – 1 0.0651 856 8524 exclusion phecode
512.3 Abnormal chest sounds Respiratory 1.09 0.892 – 1.33 0.387 126 1253 exclusion phecode
512.7 Shortness of breath Respiratory 0.992 0.96 – 1.03 0.629 5682 19763 exclusion phecode
512.8 Cough Respiratory 0.965 0.933 – 0.998 0.0378 5445 19783 exclusion phecode
512.9 Other dyspnea Respiratory 0.977 0.947 – 1.01 0.143 6302 19788 exclusion phecode
513 Respiratory abnormalities Respiratory 0.976 0.939 – 1.01 0.22 3687 25516 exclusion phecode
513.3 Hypoventilation Respiratory 0.93 0.807 – 1.07 0.315 262 2613 exclusion phecode
513.31 Apnea Respiratory 0.988 0.798 – 1.22 0.909 121 1209 exclusion phecode
513.32 Orthopnea Respiratory 0.967 0.715 – 1.29 0.817 58 579 exclusion phecode
513.4 Hyperventilation Respiratory 1.13 1.04 – 1.19 0.0917 185 1840 exclusion phecode
513.8 Disorders of diaphragm Respiratory 0.996 0.813 – 1.21 0.965 134 1340 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 0.969 0.928 – 1.01 0.157 3159 23315 exclusion phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 1.03 0.773 – 1.08 0.818 96 954 exclusion phecode
514.2 Solitary pulmonary nodule Respiratory 0.975 0.912 – 1.04 0.464 1275 12706 exclusion phecode
516 Abnormal sputum Respiratory 1.02 0.907 – 1.15 0.727 370 3692 exclusion phecode
516.1 Hemoptysis Respiratory 0.98 0.867 – 1.11 0.742 336 3354 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.976 0.941 – 1.01 0.2 4181 25923 exclusion phecode
519.1 Tracheostomy complications Respiratory 0.982 0.923 – 1.02 0.85 98 980 exclusion phecode
519.2 Respiratory complications Respiratory 0.946 0.806 – 1.11 0.489 211 2104 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.07 0.879 – 1.11 0.178 462 4597 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.971 0.933 – 1.01 0.138 3657 24661 exclusion phecode
520 Disorders of tooth development Digestive 1 0.858 – 1.17 0.959 175 1748 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.696 0.504 – 0.926 0.0157 64 631 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 1.15 0.961 – 1.37 0.12 114 1118 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 0.979 0.869 – 1.1 0.728 358 3565 exclusion phecode
521.1 Dental caries Digestive 0.984 0.871 – 1.11 0.797 338 3368 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 0.95 0.816 – 1.1 0.495 206 2054 exclusion phecode
522.5 Periapical abscess Digestive 0.941 0.8 – 1.1 0.458 180 1791 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.02 0.889 – 1.16 0.795 272 2710 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.11 0.93 – 1.32 0.24 150 1500 exclusion phecode
523.31 Acute periodontitis Digestive 1.09 0.909 – 1.31 0.334 137 1370 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.914 0.763 – 1.09 0.315 147 1462 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.01 0.81 – 1.26 0.907 95 946 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.931 0.836 – 1.03 0.187 445 4447 exclusion phecode
525.1 Loss of teeth or edentulism Digestive 1.01 0.804 – 1.25 0.96 109 1084 exclusion phecode
526 Diseases of the jaws Digestive 0.991 0.926 – 1.06 0.779 1104 11028 exclusion phecode
526.1 Cysts of the jaws Digestive 1.05 0.88 – 1.26 0.567 137 1353 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.05 0.829 – 1.09 0.581 140 1394 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.01 0.919 – 1.1 0.878 544 5440 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.982 0.878 – 1.1 0.746 368 3680 exclusion phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 1.12 0.97 – 1.29 0.118 221 2194 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.92 0.688 – 1.19 0.465 104 1030 exclusion phecode
526.9 Jaw disease NOS Digestive 0.997 0.727 – 1.03 0.969 214 2127 exclusion phecode
527 Diseases of the salivary glands Digestive 0.942 0.863 – 1.03 0.181 765 7626 exclusion phecode
527.2 Sialoadenitis Digestive 0.891 0.768 – 1.03 0.122 231 2310 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 0.99 0.78 – 1.03 0.866 394 3924 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 0.95 0.81 – 0.98 0.583 125 1250 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.966 0.904 – 1.03 0.317 1241 12362 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.01 0.877 – 1.16 0.89 284 2821 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.98 0.715 – 1.33 0.895 66 660 exclusion phecode
528.12 Oral aphthae Digestive 1.03 0.828 – 1.28 0.782 116 1150 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.842 0.674 – 1.04 0.116 107 1070 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.742 0.558 – 0.974 0.0323 73 722 exclusion phecode
528.5 Diseases of lips Digestive 1.06 0.98 – 1.13 0.433 207 2070 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 0.951 0.918 – 0.996 0.646 81 800 exclusion phecode
528.7 Sialolithiasis Digestive 0.716 0.564 – 0.901 0.00456 92 920 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 0.885 0.776 – 1.01 0.0657 357 3566 exclusion phecode
529.1 Glossitis Digestive 0.959 0.842 – 0.994 0.709 75 750 exclusion phecode
529.6 Glossodynia Digestive 0.989 0.738 – 1.32 0.938 66 660 exclusion phecode
530 Diseases of esophagus Digestive 0.964 0.938 – 0.99 0.00791 9369 20357 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.965 0.939 – 0.992 0.0115 8940 20358 exclusion phecode
530.11 GERD Digestive 0.964 0.938 – 0.992 0.0109 8565 20359 exclusion phecode
530.12 Ulcer of esophagus Digestive 0.876 0.657 – 0.912 0.0832 211 2110 exclusion phecode
530.13 Barrett's esophagus Digestive 0.922 0.704 – 0.956 0.193 309 3081 exclusion phecode
530.14 Reflux esophagitis Digestive 0.939 0.874 – 1.01 0.0814 1072 10605 exclusion phecode
530.15 Eosinophilic esophagitis Digestive 0.854 0.635 – 1.14 0.277 64 640 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.881 0.765 – 1.01 0.0729 278 2780 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 0.874 0.792 – 0.963 0.00655 554 5524 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.1 0.965 – 1.25 0.153 283 2821 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.01 0.955 – 1.31 0.95 94 923 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.969 0.891 – 1.02 0.817 54 532 exclusion phecode
530.9 Heartburn Digestive 0.982 0.908 – 1.06 0.651 800 7949 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.984 0.912 – 1.06 0.667 911 9101 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.948 0.798 – 1.12 0.525 204 2027 exclusion phecode
531.2 Gastric ulcer Digestive 0.973 0.874 – 1.08 0.608 453 4528 exclusion phecode
531.3 Duodenal ulcer Digestive 0.877 0.745 – 1.03 0.111 211 2110 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 0.974 0.864 – 1.1 0.668 366 3654 exclusion phecode
531.5 Gastrojejunal ulcer Digestive 1.08 0.98 – 1.11 0.468 67 651 exclusion phecode
532 Dysphagia Digestive 0.942 0.902 – 0.984 0.00749 2947 18985 exclusion phecode
535 Gastritis and duodenitis Digestive 0.918 0.857 – 0.983 0.0146 1122 11196 exclusion phecode
535.1 Acute gastritis Digestive 1.02 0.982 – 1.08 0.844 75 750 exclusion phecode
535.2 Atrophic gastritis Digestive 0.982 0.78 – 1.23 0.878 104 1040 exclusion phecode
535.6 Duodenitis Digestive 0.82 0.688 – 0.972 0.0227 181 1805 exclusion phecode
535.8 Other specified gastritis Digestive 0.921 0.808 – 1.05 0.213 327 3251 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.949 0.861 – 1.04 0.282 568 5672 exclusion phecode
536 Disorders of function of stomach Digestive 0.944 0.887 – 1 0.0631 1381 13654 exclusion phecode
536.3 Gastroparesis Digestive 1.06 0.928 – 1.21 0.38 275 2750 exclusion phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.01 0.822 – 1.25 0.885 176 1752 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.909 0.848 – 0.974 0.00699 1083 10692 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 0.928 0.876 – 0.982 0.00969 1624 16210 exclusion phecode
537.1 Lesions of stomach and duodenum Digestive 0.758 0.53 – 1.06 0.11 61 609 exclusion phecode
539 Bariatric surgery Digestive 0.992 0.913 – 1.08 0.854 692 6920 exclusion phecode
540 Appendiceal conditions Digestive 0.994 0.866 – 1.14 0.935 246 2460 exclusion phecode
540.1 Appendicitis Digestive 0.995 0.855 – 1.15 0.945 203 2030 exclusion phecode
540.11 Acute appendicitis Digestive 1.05 0.885 – 1.24 0.578 164 1640 exclusion phecode
550 Abdominal hernia Digestive 0.961 0.925 – 0.998 0.038 3863 25033 exclusion phecode
550.1 Inguinal hernia Digestive 0.948 0.856 – 1.04 0.139 1025 10084 exclusion phecode
550.2 Diaphragmatic hernia Digestive 0.957 0.902 – 1.01 0.141 1541 14916 exclusion phecode
550.3 Femoral hernia Digestive 0.739 0.488 – 0.969 0.0266 68 680 exclusion phecode
550.4 Umbilical hernia Digestive 0.93 0.857 – 1.01 0.0797 762 7620 exclusion phecode
550.5 Ventral hernia Digestive 0.981 0.772 – 1.02 0.592 855 8521 exclusion phecode
550.6 Incisional hernia Digestive 0.948 0.871 – 1.03 0.218 688 6880 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.07 0.991 – 1.15 0.0829 831 8236 exclusion phecode
555.1 Regional enteritis Digestive 1.03 0.936 – 1.13 0.554 524 5211 exclusion phecode
555.2 Ulcerative colitis Digestive 1.13 1.02 – 1.24 0.0169 478 4766 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.15 1.02 – 1.3 0.0228 305 3050 exclusion phecode
556 Ulceration of the lower GI tract Digestive 0.887 0.778 – 1.01 0.0716 329 3280 exclusion phecode
556.1 Ulceration of intestine Digestive 0.902 0.782 – 1.04 0.151 283 2808 exclusion phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 0.72 0.474 – 0.939 0.0156 78 779 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.976 0.896 – 1.06 0.573 644 6426 exclusion phecode
557.1 Celiac disease Digestive 0.981 0.821 – 1.17 0.829 155 1550 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1 0.941 – 1.07 0.948 1284 12803 exclusion phecode
559 Ileostomy status Digestive 1.01 0.914 – 1.1 0.916 553 5505 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.01 0.956 – 1.06 0.778 1864 16390 exclusion phecode
560.1 Paralytic ileus Digestive 1.03 0.964 – 1.1 0.378 1152 11328 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.959 0.815 – 1.12 0.603 198 1974 exclusion phecode
560.4 Other intestinal obstruction Digestive 0.987 0.922 – 1.06 0.702 1100 10934 exclusion phecode
561 Symptoms involving digestive system Digestive 0.977 0.944 – 1.01 0.192 4882 19486 exclusion phecode
561.1 Diarrhea Digestive 0.976 0.938 – 1.02 0.244 3477 19276 exclusion phecode
561.2 Flatulence Digestive 0.933 0.882 – 0.986 0.0145 1632 15205 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 0.994 0.953 – 1.04 0.77 3634 16139 exclusion phecode
562.1 Diverticulosis Digestive 0.992 0.951 – 1.03 0.703 3524 15965 exclusion phecode
562.2 Diverticulitis Digestive 1.04 0.939 – 1.14 0.485 535 5299 exclusion phecode
563 Constipation Digestive 0.995 0.957 – 1.03 0.781 3788 19204 exclusion phecode
564 Functional digestive disorders Digestive 0.971 0.936 – 1.01 0.114 4139 19471 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 0.968 0.913 – 1.03 0.273 1436 12835 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 0.963 0.914 – 1.01 0.157 1923 16754 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 0.965 0.899 – 1.03 0.319 987 9822 exclusion phecode
565 Anal and rectal conditions Digestive 1.02 0.963 – 1.07 0.544 1772 17627 exclusion phecode
565.1 Anal and rectal polyp Digestive 1 0.914 – 1.1 0.987 670 6697 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.02 0.933 – 1.11 0.661 620 6174 exclusion phecode
568 Other disorders of peritoneum Digestive 0.954 0.891 – 1.02 0.178 1063 10607 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 0.956 0.884 – 1.03 0.255 807 8070 exclusion phecode
569 Other disorders of intestine Digestive 0.982 0.938 – 1.03 0.447 2439 22843 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.04 0.994 – 1.07 0.723 77 763 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.02 0.954 – 1.1 0.522 1013 10130 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 0.981 0.933 – 1.03 0.462 1990 19480 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 0.981 0.93 – 1.03 0.469 1780 17776 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.983 0.881 – 1.09 0.754 431 4304 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 0.858 0.691 – 1.06 0.155 110 1100 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.965 0.873 – 1.07 0.482 491 4910 exclusion phecode
571.81 Portal hypertension Digestive 0.965 0.853 – 1.09 0.567 320 3200 exclusion phecode
572 Ascites (non malignant) Digestive 0.981 0.924 – 1.04 0.518 1427 14260 exclusion phecode
573 Other disorders of liver Digestive 0.942 0.898 – 0.988 0.0141 2426 21271 exclusion phecode
573.1 Chronic passive congestion of liver Digestive 1.11 0.814 – 1.51 0.488 57 565 exclusion phecode
573.2 Liver replaced by transplant Digestive 0.901 0.835 – 0.932 0.209 191 1901 exclusion phecode
573.3 Hepatomegaly Digestive 0.899 0.732 – 1.1 0.299 123 1230 exclusion phecode
573.4 Acute and subacute necrosis of liver Digestive 1 0.827 – 1.21 0.979 132 1317 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 0.943 0.849 – 1.05 0.268 477 4765 exclusion phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.04 0.964 – 1.12 0.304 870 8637 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 0.976 0.897 – 1.06 0.433 1398 13942 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 0.957 0.896 – 1.02 0.18 1269 12656 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 0.981 0.93 – 1.03 0.466 1798 17889 exclusion phecode
574.1 Cholelithiasis Digestive 0.98 0.927 – 1.04 0.469 1628 16255 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.955 0.808 – 1.12 0.578 178 1780 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.951 0.837 – 1.08 0.437 326 3260 exclusion phecode
574.2 Calculus of bile duct Digestive 0.912 0.816 – 1.02 0.0959 426 4249 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.982 0.889 – 1.08 0.721 491 4893 exclusion phecode
575 Other biliary tract disease Digestive 0.967 0.91 – 1.03 0.283 1369 13683 exclusion phecode
575.1 Cholangitis Digestive 0.898 0.768 – 1.05 0.171 224 2232 exclusion phecode
575.2 Obstruction of bile duct Digestive 0.948 0.847 – 1.06 0.353 398 3970 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 1.18 0.95 – 1.46 0.128 101 1010 exclusion phecode
575.7 Other disorders of gallbladder Digestive 0.996 0.909 – 1.09 0.922 586 5844 exclusion phecode
575.8 Other disorders of biliary tract Digestive 0.907 0.83 – 0.991 0.0311 663 6625 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.1 0.884 – 1.38 0.37 99 990 exclusion phecode
577 Diseases of pancreas Digestive 0.968 0.908 – 1.03 0.317 1282 12802 exclusion phecode
577.1 Acute pancreatitis Digestive 0.964 0.877 – 1.06 0.449 550 5488 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.07 0.938 – 1.21 0.319 294 2940 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.933 0.824 – 1.06 0.272 347 3424 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 0.983 0.939 – 1.03 0.448 2525 23777 exclusion phecode
578.1 Hematemesis Digestive 1.05 0.92 – 1.2 0.462 281 2803 exclusion phecode
578.2 Blood in stool Digestive 0.989 0.934 – 1.05 0.717 1568 15580 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 0.926 0.866 – 0.99 0.0252 1169 11604 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.982 0.907 – 1.06 0.658 854 8501 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.02 0.976 – 1.06 0.422 3083 24286 exclusion phecode
579.2 Splenomegaly Digestive 0.97 0.872 – 1.08 0.567 465 4646 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.92 0.829 – 1.02 0.112 523 5223 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.931 0.851 – 1.02 0.115 663 6626 exclusion phecode
580.1 Glomerulonephritis Genitourinary 0.877 0.843 – 0.947 0.0968 160 1600 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.946 0.918 – 1 0.618 51 510 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.678 0.483 – 0.903 0.0108 64 639 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.952 0.905 – 1.01 0.685 55 544 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1 0.754 – 1.32 0.999 78 780 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.938 0.844 – 1.04 0.222 499 4986 exclusion phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.02 0.894 – 1.17 0.736 298 2977 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.926 0.877 – 0.985 0.264 256 2560 exclusion phecode
580.4 Renal sclerosis, NOS Genitourinary 0.968 0.794 – 1.18 0.745 130 1300 exclusion phecode
585 Renal failure Genitourinary 0.993 0.953 – 1.03 0.744 3458 20778 exclusion phecode
585.1 Acute renal failure Genitourinary 0.977 0.929 – 1.03 0.368 2218 17709 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.03 0.928 – 1.13 0.609 530 5283 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.999 0.949 – 1.05 0.954 2200 17131 exclusion phecode
585.31 Renal dialysis Genitourinary 0.987 0.874 – 1.11 0.824 358 3580 exclusion phecode
585.32 End stage renal disease Genitourinary 1.02 0.917 – 1.12 0.763 511 5109 exclusion phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 0.999 0.923 – 1.08 0.978 882 8499 exclusion phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1 0.887 – 1.13 0.963 354 3533 exclusion phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 0.973 0.861 – 1.1 0.653 394 3919 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 0.984 0.95 – 1.02 0.367 4597 24047 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1 0.844 – 1.19 0.985 162 1614 exclusion phecode
586.11 Small kidney Genitourinary 1.04 0.891 – 1.07 0.724 78 777 exclusion phecode
586.12 Vesicoureteral reflux Genitourinary 0.976 0.756 – 1.25 0.838 74 740 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.02 0.942 – 1.1 0.637 909 8889 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.21 0.975 – 1.49 0.0782 107 1059 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.02 0.95 – 1.08 0.654 1121 11181 exclusion phecode
587 Kidney replaced by transpant Genitourinary 0.987 0.886 – 1.1 0.806 488 4871 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 0.984 0.881 – 1.1 0.773 451 4502 exclusion phecode
588.1 Renal osteodystrophy Genitourinary 0.863 0.679 – 1.06 0.158 130 1296 exclusion phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 0.924 0.766 – 1.1 0.362 190 1878 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 0.985 0.902 – 1.07 0.729 684 6821 exclusion phecode
590 Pyelonephritis Genitourinary 0.989 0.861 – 1.13 0.779 731 7290 exclusion phecode
591 Urinary tract infection Genitourinary 0.974 0.942 – 1.01 0.112 5452 22952 exclusion phecode
592 Cystitis and urethritis Genitourinary 0.976 0.912 – 1.04 0.472 1138 11348 exclusion phecode
592.1 Cystitis Genitourinary 1 0.932 – 1.07 0.991 1068 10653 exclusion phecode
592.11 Acute cystitis Genitourinary 0.97 0.878 – 1.07 0.545 533 5281 exclusion phecode
592.12 Chronic cystitis Genitourinary 0.927 0.879 – 0.98 0.396 155 1536 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.03 0.894 – 1.19 0.67 232 2320 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.853 0.804 – 0.877 0.116 81 802 exclusion phecode
593 Hematuria Genitourinary 0.968 0.924 – 1.01 0.179 2486 21121 exclusion phecode
593.1 Gross hematuria Genitourinary 0.933 0.842 – 1.03 0.18 562 5464 exclusion phecode
593.2 Microscopic hematuria Genitourinary 0.97 0.838 – 1.12 0.677 260 2592 exclusion phecode
594 Urinary calculus Genitourinary 1.02 0.976 – 1.06 0.417 2847 25144 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.03 0.98 – 1.07 0.276 2507 23747 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.11 0.957 – 1.31 0.146 230 2276 exclusion phecode
594.3 Calculus of ureter Genitourinary 1 0.93 – 1.08 0.921 845 8428 exclusion phecode
594.8 Renal colic Genitourinary 0.99 0.844 – 1.16 0.901 194 1940 exclusion phecode
595 Hydronephrosis Genitourinary 1 0.933 – 1.07 0.989 1042 10410 exclusion phecode
596 Other disorders of bladder Genitourinary 0.974 0.921 – 1.03 0.347 1681 15907 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 0.89 0.76 – 1.04 0.139 250 2472 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1 0.923 – 1.09 0.968 759 7579 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.02 0.937 – 1.11 0.665 693 6902 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.04 0.938 – 1.16 0.426 440 4350 exclusion phecode
597.2 Urinary complications NEC Genitourinary 0.995 0.886 – 1.12 0.939 387 3857 exclusion phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.14 0.895 – 1.44 0.284 83 820 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 0.992 0.928 – 1.06 0.805 1201 11933 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.05 0.954 – 1.16 0.307 576 5735 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.98 0.953 – 1.01 0.172 7844 21512 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.973 0.634 – 1.01 0.642 305 3024 exclusion phecode
599.2 Retention of urine Genitourinary 0.988 0.947 – 1.03 0.59 3032 19646 exclusion phecode
599.3 Dysuria Genitourinary 0.959 0.913 – 1.01 0.0924 2165 18489 exclusion phecode
599.4 Urinary incontinence Genitourinary 1.01 0.968 – 1.05 0.688 3155 18822 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 0.975 0.933 – 1.02 0.244 2876 19849 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.05 0.93 – 1.19 0.406 365 3643 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 0.982 0.936 – 1.03 0.46 2349 17485 exclusion phecode
599.9 Other abnormality of urination Genitourinary 0.978 0.921 – 1.04 0.457 1498 14372 exclusion phecode
600 Hyperplasia of prostate Genitourinary 0.978 0.924 – 1.04 0.456 2243 7947 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 1.02 0.88 – 1.18 0.716 555 5331 exclusion phecode
601.1 Prostatitis Genitourinary 1.07 0.903 – 1.27 0.373 266 2638 exclusion phecode
601.11 Acute prostatitis Genitourinary 1.17 0.856 – 1.6 0.317 58 553 exclusion phecode
601.12 Chronic prostatitis Genitourinary 1.29 0.948 – 1.87 0.0956 53 509 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.899 0.752 – 1.07 0.235 184 1815 exclusion phecode
601.4 Balanoposthitis Genitourinary 0.809 0.615 – 1.05 0.116 71 698 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.03 0.991 – 1.08 0.754 81 782 exclusion phecode
602 Other disorders of prostate Genitourinary 0.718 0.57 – 0.859 0.000609 178 1727 exclusion phecode
603 Other disorders of testis Genitourinary 1.02 0.846 – 1.22 0.817 220 2192 exclusion phecode
603.1 Hydrocele Genitourinary 0.956 0.75 – 0.995 0.609 162 1614 exclusion phecode
603.2 Spermatocele Genitourinary 1.02 0.73 – 1.41 0.906 51 509 exclusion phecode
604 Disorders of penis Genitourinary 1 0.886 – 1.13 0.996 354 3511 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.886 0.723 – 1.08 0.233 129 1290 exclusion phecode
604.3 Peyronie's disease Genitourinary 0.958 0.753 – 1.21 0.723 94 940 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 0.984 0.925 – 1.05 0.62 1514 8788 exclusion phecode
608 Other disorders of male genital organs Genitourinary 0.993 0.92 – 1.07 0.853 922 8988 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.07 0.836 – 1.13 0.326 225 2244 exclusion phecode
609.1 Infertility, male Genitourinary 1.12 0.903 – 1.18 0.125 177 1770 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.871 0.594 – 1.19 0.352 61 590 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.996 0.948 – 1.05 0.861 2233 11530 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.948 0.862 – 1.04 0.268 562 5522 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 1.01 0.96 – 1.06 0.688 1942 11506 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.05 0.86 – 1.28 0.601 151 1490 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.985 0.948 – 1.02 0.453 4078 12749 exclusion phecode
611.1 Abnormal mammogram Genitourinary 0.987 0.946 – 1.03 0.546 3365 11545 exclusion phecode
611.11 Mammographic microcalcification Genitourinary 0.999 0.922 – 1.08 0.98 807 7873 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.986 0.94 – 1.03 0.563 2397 12643 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.977 0.896 – 1.07 0.6 652 6511 exclusion phecode
612.1 Galactorrhea Genitourinary 1.01 0.809 – 1.26 0.918 86 846 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.96 0.869 – 1.06 0.416 505 5050 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.997 0.949 – 1.05 0.913 2083 14991 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.1 0.979 – 1.23 0.105 356 3557 exclusion phecode
613.5 Mastodynia Genitourinary 1.01 0.944 – 1.09 0.686 943 9313 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 0.96 0.873 – 1.06 0.4 544 5372 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1.04 0.894 – 1.08 0.438 490 4900 exclusion phecode
613.9 Breast disorder NOS Genitourinary 1.03 0.932 – 1.14 0.547 502 4996 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.991 0.945 – 1.04 0.709 2225 13521 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.987 0.851 – 1.14 0.865 218 2180 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.984 0.859 – 1.12 0.816 249 2490 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.13 0.927 – 1.38 0.213 110 1092 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.857 0.681 – 1.07 0.173 91 910 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.989 0.762 – 1.03 0.912 91 902 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.99 0.94 – 1.04 0.707 1879 13146 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.982 0.829 – 1.16 0.828 157 1570 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1 0.949 – 1.06 0.924 1634 12698 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.883 0.673 – 1.15 0.355 71 710 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.852 0.687 – 1.04 0.112 127 1264 exclusion phecode
615 Endometriosis Genitourinary 0.996 0.915 – 1.08 0.923 653 6530 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 0.919 0.781 – 1.08 0.295 185 1850 exclusion phecode
618 Genital prolapse Genitourinary 0.95 0.886 – 1.02 0.15 1010 9911 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 0.945 0.874 – 1.02 0.153 813 8114 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.901 0.795 – 1.02 0.0967 331 3304 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.959 0.83 – 1.11 0.564 243 2412 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.981 0.914 – 1.02 0.848 78 780 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1 0.958 – 1.05 0.894 2418 13846 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.07 0.963 – 1.19 0.191 457 4566 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 1.01 0.888 – 1.14 0.929 312 3113 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.02 0.889 – 1.17 0.767 251 2509 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.979 0.912 – 1.05 0.557 945 9337 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.953 0.864 – 1.05 0.333 555 5532 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 0.978 0.838 – 1.14 0.77 202 1998 exclusion phecode
620.1 Dysplasia of cervix Genitourinary 0.946 0.652 – 0.988 0.664 65 642 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.948 0.827 – 1.08 0.432 268 2670 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.951 0.885 – 1.02 0.171 963 9484 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.971 0.897 – 1.05 0.466 788 7783 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 0.912 0.792 – 1.05 0.194 262 2612 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.09 0.891 – 1.32 0.401 128 1275 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.976 0.886 – 1.07 0.625 509 5081 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.842 0.658 – 1.07 0.159 86 849 exclusion phecode
624.9 stress incontinence, female Genitourinary 1 0.94 – 1.07 0.903 1090 10634 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.98 0.942 – 1.02 0.334 3565 11985 exclusion phecode
625.1 Dyspareunia Genitourinary 0.967 0.881 – 1.06 0.475 577 5751 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.961 0.921 – 1 0.0701 3133 10549 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.969 0.925 – 1.01 0.182 2526 9811 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.978 0.89 – 1.07 0.645 512 4742 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 0.957 0.899 – 1.02 0.166 1274 7706 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 0.983 0.918 – 1.05 0.623 1045 7692 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 1 0.825 – 1.04 0.99 504 5031 exclusion phecode
626.15 Infertility, female, associated with anovulation Genitourinary 1.01 0.789 – 1.05 0.87 233 2326 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.908 0.833 – 0.989 0.0282 634 5538 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.898 0.762 – 1.05 0.188 184 1834 exclusion phecode
626.8 Infertility, female Genitourinary 0.941 0.844 – 1.05 0.262 397 3631 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.01 0.959 – 1.05 0.831 2517 10696 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 0.96 0.883 – 1.04 0.342 744 7177 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.99 0.934 – 1.05 0.736 1581 10293 exclusion phecode
627.21 Symptomatic artificial menopause Genitourinary 1.02 0.792 – 1.31 0.856 77 764 exclusion phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 1.09 0.935 – 1.26 0.266 208 2080 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.12 1.01 – 1.24 0.0378 443 4409 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 0.987 0.857 – 1.14 0.857 238 2371 exclusion phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.917 0.738 – 1.14 0.428 109 1082 exclusion phecode
628 Ovarian cyst Genitourinary 0.954 0.896 – 1.02 0.145 1250 9406 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.964 0.804 – 1.14 0.497 352 3520 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.948 0.836 – 0.985 0.422 158 1580 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.1 0.963 – 1.25 0.161 262 2614 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.01 0.922 – 1.06 0.845 165 1650 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.1 1.05 – 1.14 0.227 120 1200 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.944 0.866 – 1.03 0.193 627 4839 exclusion phecode
636.1 Threatened premature labor Pregnancy Complications 1 0.746 – 1.04 0.994 193 1930 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.937 0.867 – 0.972 0.316 179 1790 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.932 0.817 – 0.964 0.204 253 2530 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 0.984 0.892 – 1.08 0.74 483 4437 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.913 0.78 – 0.938 0.122 229 2290 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.902 0.831 – 0.935 0.272 111 1110 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.91 0.723 – 1.12 0.36 106 1060 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1 0.631 – 1.05 0.976 58 580 exclusion phecode
644 Anemia during pregnancy Pregnancy Complications 0.932 0.866 – 0.96 0.5 53 530 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.949 0.813 – 1.1 0.479 203 2030 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.945 0.872 – 0.979 0.316 297 2968 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.04 0.981 – 1.07 0.669 109 1090 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.936 0.885 – 0.974 0.44 110 1095 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.952 0.873 – 1.04 0.257 631 4770 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.959 0.801 – 0.99 0.529 182 1820 exclusion phecode
650 Normal delivery Pregnancy Complications 0.999 0.911 – 1.09 0.986 539 4838 exclusion phecode
651 Multiple gestation Pregnancy Complications 1.01 0.713 – 1.06 0.933 76 760 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1.05 0.94 – 1.18 0.362 335 3346 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.986 0.918 – 1.02 0.804 294 2935 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 0.975 0.863 – 1.1 0.678 327 3270 exclusion phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.05 0.879 – 1.1 0.451 269 2690 exclusion phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 0.943 0.775 – 1.14 0.551 115 1150 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.998 0.926 – 1.07 0.95 861 6135 exclusion phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 0.918 0.804 – 1.05 0.203 258 2580 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1 0.839 – 1.2 0.962 149 1490 exclusion phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 1.02 0.952 – 1.06 0.858 51 510 exclusion phecode
658
Maternal complication of pregnancy affecting
Maternal complication of pregnancy affecting fetus or newborn
 Pregnancy Complications 0.938 0.767 – 1.14 0.526 121 1210 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 1.01 0.906 – 1.13 0.822 359 3399 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.898 0.788 – 1.02 0.105 268 2664 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.949 0.865 – 1.04 0.262 545 4596 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.948 0.854 – 1.05 0.318 419 3688 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.976 0.897 – 1.01 0.737 120 1200 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.959 0.843 – 0.987 0.639 75 750 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.03 0.992 – 1.08 0.113 3226 25620 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.04 0.936 – 1.14 0.498 502 5008 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.964 0.867 – 1.07 0.499 490 4878 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1 0.895 – 1.12 0.958 425 4233 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.01 0.929 – 1.1 0.776 719 7170 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.978 0.851 – 1.12 0.75 275 2741 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.04 0.957 – 1.13 0.36 737 7337 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.03 0.951 – 1.12 0.439 772 7704 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.02 0.903 – 1.15 0.753 332 3302 exclusion phecode
686.2 Impetigo Dermatologic 0.961 0.838 – 0.997 0.645 117 1151 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.09 0.846 – 1.43 0.463 81 810 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 0.727 0.533 – 0.982 0.0367 72 720 exclusion phecode
687 Symptoms affecting skin Dermatologic 0.964 0.914 – 1.02 0.19 1923 18267 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.962 0.925 – 1 0.0614 3507 23571 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 0.97 0.913 – 1.03 0.325 1489 14692 exclusion phecode
687.3 Changes in skin texture Dermatologic 0.93 0.578 – 0.965 0.472 108 1080 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 0.971 0.932 – 1.01 0.165 3091 23515 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.991 0.953 – 1.03 0.652 4922 25501 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.968 0.877 – 1.07 0.511 671 6685 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.978 0.886 – 1.08 0.657 662 6591 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.908 0.649 – 0.944 0.155 252 2510 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.998 0.908 – 1.1 0.962 733 7285 exclusion phecode
694.1 Vitiligo Dermatologic 1.01 0.945 – 1.04 0.954 55 537 exclusion phecode
694.2 Other dyschromia Dermatologic 0.995 0.898 – 1.1 0.916 646 6423 exclusion phecode
695 Erythematous conditions Dermatologic 0.972 0.924 – 1.02 0.28 2176 19590 exclusion phecode
695.3 Rosacea Dermatologic 0.989 0.913 – 1.07 0.788 973 9708 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 0.935 0.831 – 1.05 0.254 385 3840 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.907 0.863 – 1.34 0.412 73 730 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 0.933 0.828 – 1.05 0.243 371 3699 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 0.968 0.842 – 1.11 0.641 283 2825 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 0.97 0.863 – 1.09 0.604 392 3916 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 0.988 0.864 – 1.13 0.859 317 3160 exclusion phecode
696 Psoriasis and related disorders Dermatologic 0.969 0.881 – 1.06 0.514 599 5979 exclusion phecode
696.4 Psoriasis Dermatologic 0.976 0.884 – 1.08 0.622 558 5563 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 0.985 0.886 – 1.09 0.783 487 4851 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 1.1 0.924 – 1.31 0.271 162 1610 exclusion phecode
697 Sarcoidosis Dermatologic 0.804 0.68 – 0.947 0.00928 200 2000 exclusion phecode
698 Pruritus and related conditions Dermatologic 1 0.934 – 1.07 0.982 1083 10755 exclusion phecode
700 Corns and callosities Dermatologic 0.894 0.8 – 0.999 0.0489 489 4876 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.992 0.951 – 1.03 0.706 3381 25494 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 1.02 0.948 – 1.06 0.847 189 1881 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.07 0.992 – 1.16 0.0759 1114 11124 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 0.907 0.762 – 1.06 0.181 252 2519 exclusion phecode
701.4 Keloid scar Dermatologic 0.993 0.63 – 1.03 0.923 257 2556 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 1.07 0.912 – 1.26 0.385 232 2299 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.01 0.971 – 1.06 0.528 4029 20696 exclusion phecode
702.1 Actinic keratosis Dermatologic 1.09 1.02 – 1.15 0.0053 2483 18119 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 0.995 0.947 – 1.05 0.843 3023 20930 exclusion phecode
703 Diseases of nail, NOS Dermatologic 0.896 0.8 – 1 0.0566 518 5164 exclusion phecode
703.1 Ingrowing nail Dermatologic 1.06 0.944 – 1.18 0.336 407 4057 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 0.936 0.88 – 0.995 0.0351 1477 14674 exclusion phecode
704.1 Alopecia Dermatologic 0.922 0.843 – 1.01 0.0745 665 6581 exclusion phecode
704.2 Hirsutism Dermatologic 0.994 0.83 – 1.19 0.947 148 1473 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.925 0.846 – 1.01 0.0857 749 7454 exclusion phecode
705 Disorders of sweat glands Dermatologic 1.12 0.975 – 1.29 0.104 231 2304 exclusion phecode
705.1 Dyshidrosis Dermatologic 1.15 1.1 – 1.21 0.17 75 747 exclusion phecode
705.3 Hidradenitis Dermatologic 1.03 0.945 – 1.08 0.693 137 1355 exclusion phecode
705.8 Hyperhidrosis Dermatologic 0.968 0.864 – 1.08 0.566 415 4140 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1.02 0.979 – 1.07 0.305 2769 24962 exclusion phecode
706.1 Acne Dermatologic 0.983 0.913 – 1.06 0.658 890 8472 exclusion phecode
706.2 Sebaceous cyst Dermatologic 1.05 0.984 – 1.11 0.151 1566 15443 exclusion phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 1.11 1 – 1.23 0.0471 655 6472 exclusion phecode
707 Chronic ulcer of skin Dermatologic 0.965 0.893 – 1.04 0.371 929 9243 exclusion phecode
707.1 Decubitus ulcer Dermatologic 0.975 0.863 – 1.1 0.678 388 3871 exclusion phecode
707.2 Chronic ulcer of leg or foot Dermatologic 0.956 0.849 – 1.07 0.449 396 3934 exclusion phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1 0.872 – 1.15 0.991 298 2980 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 1.01 0.922 – 1.11 0.803 568 5660 exclusion phecode
709.2 Sicca syndrome Dermatologic 0.999 0.857 – 1.16 0.986 220 2195 exclusion phecode
709.3 Systemic sclerosis Dermatologic 1.03 0.854 – 1.25 0.723 143 1430 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.973 0.846 – 1.12 0.691 262 2596 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.925 0.845 – 1.01 0.0866 662 6611 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 0.914 0.834 – 1 0.052 633 6320 exclusion phecode
710.11 Acute osteomyelitis Musculoskeletal 0.884 0.759 – 1.03 0.105 238 2380 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.94 0.801 – 1.1 0.443 204 2031 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.932 0.846 – 1.03 0.153 562 5610 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 1.03 0.892 – 1.19 0.658 248 2473 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.05 0.997 – 1.09 0.58 148 1460 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.09 0.863 – 1.37 0.46 91 903 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.786 0.634 – 0.967 0.0234 135 1350 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 0.821 0.608 – 1.08 0.155 76 760 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 0.985 0.919 – 1.06 0.677 1068 10604 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.95 0.879 – 1.03 0.187 864 8611 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.943 0.847 – 1.05 0.284 443 4421 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.839 0.699 – 1 0.0537 161 1601 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.899 0.717 – 1.12 0.344 100 1000 exclusion phecode
716 Other arthropathies Musculoskeletal 0.967 0.933 – 1 0.0636 4694 22867 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.985 0.834 – 1.16 0.852 189 1888 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.917 0.803 – 1.05 0.195 314 3120 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 0.966 0.932 – 1 0.0618 4524 22669 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.02 0.819 – 1.25 0.886 122 1204 exclusion phecode
720 Spinal stenosis Musculoskeletal 1 0.956 – 1.05 0.923 2399 19696 exclusion phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1.02 0.964 – 1.08 0.473 1548 14271 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 0.986 0.946 – 1.03 0.518 3096 22029 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.999 0.957 – 1.04 0.974 2832 21530 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.951 0.862 – 1.05 0.319 525 5246 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 0.963 0.827 – 1.12 0.622 222 2220 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 0.976 0.941 – 1.01 0.205 3951 24010 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.988 0.941 – 1.04 0.622 2109 20476 exclusion phecode
722.3 Schmorl's nodes Musculoskeletal 0.973 0.78 – 1.21 0.805 109 1090 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.991 0.947 – 1.04 0.694 2578 21752 exclusion phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 0.96 0.852 – 1.08 0.503 356 3546 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.1 0.964 – 1.26 0.148 271 2707 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.03 0.927 – 1.13 0.62 506 5051 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 0.974 0.883 – 1.07 0.605 489 4883 exclusion phecode
723.1 Torticollis Musculoskeletal 1.15 0.918 – 1.42 0.218 101 1010 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 0.951 0.909 – 0.995 0.031 2463 21769 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 0.934 0.876 – 0.996 0.0383 1250 12289 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.948 0.864 – 1.04 0.247 596 5911 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 0.965 0.869 – 1.07 0.508 433 4324 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 0.972 0.909 – 1.04 0.393 1137 11318 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.981 0.95 – 1.01 0.257 5510 22783 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.95 0.913 – 0.988 0.00994 3508 22767 exclusion phecode
726.2 Synoviopathy Musculoskeletal 1.04 0.94 – 1.16 0.416 460 4596 exclusion phecode
726.3 Bursitis Musculoskeletal 1.05 0.966 – 1.14 0.242 718 7081 exclusion phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 1.09 0.944 – 1.26 0.234 234 2331 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.02 0.976 – 1.06 0.44 3359 22495 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.01 0.952 – 1.07 0.765 1470 14554 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.923 0.775 – 1.1 0.359 183 1830 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.979 0.899 – 1.06 0.616 754 7514 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 1.05 0.916 – 1.2 0.469 269 2671 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.02 0.95 – 1.1 0.545 942 9405 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.97 0.747 – 1.24 0.766 115 1150 exclusion phecode
727.8 Plica syndrome Musculoskeletal 1.22 0.976 – 1.44 0.0609 88 879 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.02 0.909 – 1.15 0.69 373 3730 exclusion phecode
728.1 Muscular calcification and ossification Musculoskeletal 1.05 0.976 – 1.09 0.65 60 590 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.03 0.792 – 1.07 0.707 159 1584 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.98 0.922 – 1.04 0.505 1429 14268 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.12 0.955 – 1.31 0.16 210 2100 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 0.942 0.872 – 1.02 0.127 923 9227 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.759 0.565 – 1 0.0537 71 710 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.961 0.901 – 1 0.708 97 966 exclusion phecode
732 Osteochondropathies Musculoskeletal 1.01 0.841 – 1.04 0.912 226 2239 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1 0.835 – 1.04 0.959 117 1158 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.989 0.945 – 1.03 0.921 60 600 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.994 0.939 – 1.05 0.849 1629 14029 exclusion phecode
733.2 Cyst of bone Musculoskeletal 0.995 0.808 – 1.22 0.958 112 1111 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.968 0.85 – 1.1 0.617 306 3054 exclusion phecode
733.6 Costochondritis Musculoskeletal 1.03 0.879 – 1.21 0.68 195 1950 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.96 0.86 – 1.07 0.467 400 3992 exclusion phecode
733.9 Chondromalacia Musculoskeletal 0.917 0.818 – 0.943 0.406 70 700 exclusion phecode
735 Acquired foot deformities Musculoskeletal 0.967 0.912 – 1.02 0.259 1543 15259 exclusion phecode
735.1 Flat foot Musculoskeletal 0.947 0.825 – 1.08 0.434 277 2752 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 0.976 0.886 – 1.08 0.629 577 5748 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.963 0.849 – 1.09 0.557 337 3360 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.954 0.783 – 1.14 0.542 210 2091 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.977 0.88 – 1.08 0.656 476 4744 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 0.942 0.848 – 1.05 0.265 474 4732 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 0.868 0.69 – 1.09 0.215 103 1030 exclusion phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.952 0.69 – 1.28 0.729 59 590 exclusion phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.958 0.791 – 1.16 0.656 143 1424 exclusion phecode
737 Curvature of spine Musculoskeletal 1.03 0.95 – 1.11 0.507 796 7899 exclusion phecode
737.1 Kyphosis (acquired) Musculoskeletal 1.16 1.01 – 1.34 0.0383 229 2290 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.01 0.922 – 1.1 0.868 636 6302 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.97 0.909 – 1.03 0.347 1305 13004 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.977 0.89 – 1.07 0.63 576 5747 exclusion phecode
739 Contracture of joint Musculoskeletal 0.923 0.807 – 1.05 0.235 274 2731 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1 0.97 – 1.03 0.917 6053 23703 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.992 0.951 – 1.04 0.719 3012 20262 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.01 0.955 – 1.06 0.834 1983 17373 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.09 0.897 – 1.32 0.381 133 1323 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.95 0.875 – 1.03 0.211 853 8031 exclusion phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 0.872 0.707 – 1.07 0.192 122 1210 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1 0.968 – 1.04 0.937 5252 22975 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.02 0.98 – 1.06 0.37 3678 26204 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 1.09 0.91 – 1.3 0.349 156 1558 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 0.957 0.865 – 1.06 0.387 504 5026 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 0.968 0.886 – 1.06 0.467 730 7244 exclusion phecode
741.4 Joint effusions Musculoskeletal 1.03 0.969 – 1.1 0.311 1216 12099 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.05 1.03 – 1.12 0.693 55 550 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.05 0.985 – 1.11 0.143 1303 12204 exclusion phecode
742.1 Loose body in joint Musculoskeletal 0.839 0.663 – 1.06 0.133 95 934 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.952 0.856 – 0.99 0.48 186 1817 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.17 0.964 – 1.42 0.105 110 1069 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 1.06 0.989 – 1.13 0.102 1101 10498 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.01 0.979 – 1.04 0.507 5897 24672 exclusion phecode
743.1 Osteoporosis Musculoskeletal 0.996 0.937 – 1.06 0.885 1593 10643 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.02 0.951 – 1.09 0.601 1248 9044 exclusion phecode
743.12 Senile osteoporosis Musculoskeletal 1.01 0.925 – 1.09 0.902 783 6734 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 0.874 0.7 – 1.08 0.221 116 1160 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.04 0.937 – 1.16 0.441 443 4411 exclusion phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 1.04 0.874 – 1.23 0.664 169 1680 exclusion phecode
743.22 Pathologic fracture of femur Musculoskeletal 1.03 0.96 – 1.06 0.789 57 561 exclusion phecode
743.4 Stress fracture Musculoskeletal 0.986 0.817 – 1.18 0.876 147 1458 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.01 0.98 – 1.05 0.429 5109 24535 exclusion phecode
745 Pain in joint Musculoskeletal 0.995 0.97 – 1.02 0.718 10780 19904 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.03 0.965 – 1.09 0.415 1431 14023 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.01 0.943 – 1.08 0.821 1174 11472 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.961 0.852 – 1.08 0.515 340 3390 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.01 0.902 – 1.12 0.92 448 4459 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.96 0.868 – 1.06 0.422 549 5250 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.02 0.976 – 1.1 0.746 278 2771 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.903 0.693 – 1.16 0.431 72 710 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.08 0.948 – 1.22 0.248 293 2920 exclusion phecode
749.1 Cleft palate Congenital Anomalies 0.985 0.934 – 1.05 0.901 54 511 exclusion phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 1.06 0.924 – 1.09 0.59 64 633 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 0.978 0.888 – 1.08 0.657 521 5210 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.05 0.903 – 1.23 0.5 208 2080 exclusion phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 1.04 0.995 – 1.08 0.678 84 840 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.933 0.824 – 1.05 0.266 311 3100 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1 0.852 – 1.17 0.982 181 1802 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.895 0.733 – 1.09 0.266 132 1310 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.97 0.906 – 1.04 0.379 1070 10653 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.903 0.805 – 1.01 0.0774 362 3599 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.959 0.842 – 1.09 0.522 263 2626 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.798 0.68 – 0.83 0.0388 82 810 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.97 0.887 – 1.06 0.493 664 6624 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.923 0.826 – 1.03 0.159 446 4432 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.02 0.856 – 1.22 0.796 152 1515 exclusion phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.09 0.865 – 1.38 0.44 84 838 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.03 0.811 – 1.07 0.581 276 2760 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.02 0.711 – 1.06 0.774 139 1390 exclusion phecode
752.11 Spina bifida Congenital Anomalies 1.04 0.958 – 1.07 0.661 99 990 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.997 0.834 – 1.03 0.967 145 1441 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.05 0.829 – 1.32 0.684 95 950 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.956 0.87 – 1.05 0.339 579 5773 exclusion phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 0.922 0.735 – 1.15 0.47 110 1100 exclusion phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 1.02 0.898 – 1.16 0.724 285 2828 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.01 0.912 – 1.12 0.859 455 4519 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.05 0.889 – 1.23 0.586 191 1905 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.998 0.864 – 1.15 0.982 219 2175 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.05 0.882 – 1.26 0.56 141 1410 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.995 0.893 – 1.11 0.931 409 4080 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.01 0.784 – 1.29 0.936 75 732 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.01 0.862 – 1.17 0.941 223 2227 exclusion phecode
757 Congenital anomalies of the integument Congenital Anomalies 1.08 0.824 – 1.4 0.568 81 802 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.823 0.649 – 1.04 0.101 88 880 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.813 0.608 – 1.08 0.148 59 583 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.932 0.817 – 1.06 0.282 285 2832 exclusion phecode
760 Back pain Symptoms 0.998 0.971 – 1.03 0.905 8028 22659 exclusion phecode
761 Cervicalgia Symptoms 0.976 0.94 – 1.01 0.222 3608 26610 exclusion phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 0.981 0.93 – 1.03 0.488 1816 17997 exclusion phecode
764 Sciatica Symptoms 0.966 0.909 – 1.03 0.267 1420 14178 exclusion phecode
765 Cervical radiculitis Symptoms 1.03 0.951 – 1.12 0.451 752 7489 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.02 0.968 – 1.07 0.466 1918 19040 exclusion phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.08 1 – 1.12 0.421 80 784 exclusion phecode
769 Nonallopathic lesions NEC Symptoms 0.939 0.864 – 1.02 0.134 761 7571 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 0.991 0.947 – 1.04 0.675 2597 20677 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.02 0.96 – 1.07 0.587 1684 16709 exclusion phecode
771.1 Swelling of limb Symptoms 0.973 0.934 – 1.01 0.176 3385 24965 exclusion phecode
771.2 Cramp of limb Symptoms 1.04 0.911 – 1.17 0.589 320 3173 exclusion phecode
772 Symptoms of the muscles Symptoms 1 0.943 – 1.07 0.937 1393 13878 exclusion phecode
772.1 Muscular wasting and disuse atrophy Symptoms 1.04 0.868 – 1.24 0.66 148 1480 exclusion phecode
772.2 Spasm of muscle Symptoms 0.972 0.892 – 1.06 0.51 675 6750 exclusion phecode
772.3 Muscle weakness Symptoms 1 0.928 – 1.08 0.922 869 8650 exclusion phecode
772.4 Rhabdomyolysis Symptoms 1.03 0.828 – 1.27 0.793 107 1058 exclusion phecode
772.6 Facial weakness Symptoms 0.982 0.822 – 1.17 0.838 188 1878 exclusion phecode
773 Pain in limb Symptoms 0.993 0.965 – 1.02 0.649 7554 23129 exclusion phecode
780 Hypothermia/Chills Symptoms 1.02 0.82 – 1.26 0.85 118 1176 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.02 0.91 – 1.14 0.748 426 4247 exclusion phecode
782.3 Edema Symptoms 0.992 0.952 – 1.03 0.706 3242 24998 exclusion phecode
782.6 Pallor and flushing Symptoms 1.07 0.945 – 1.2 0.295 333 2956 exclusion phecode
783 Fever of unknown origin Symptoms 1.01 0.977 – 1.05 0.456 3640 27007 exclusion phecode
783.1 Postprocedural fever Symptoms 1.07 0.874 – 1.3 0.513 127 1268 exclusion phecode
785 Abdominal pain Symptoms 0.983 0.958 – 1.01 0.212 9622 21069 exclusion phecode
788 Syncope and collapse Symptoms 0.985 0.936 – 1.04 0.573 1983 19629 exclusion phecode
789 Nausea and vomiting Symptoms 1.01 0.976 – 1.04 0.619 5375 25291 exclusion phecode
789.1 Persistent vomiting Symptoms 1.01 0.878 – 1.17 0.857 246 2442 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 0.922 0.849 – 1 0.0525 802 8010 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 0.941 0.676 – 0.983 0.621 67 662 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 0.955 0.913 – 1 0.0497 2593 24549 exclusion phecode
790.9 Abnormal arterial blood gases Symptoms 1.05 0.825 – 1.33 0.696 90 900 exclusion phecode
791 Gangrene Symptoms 1.12 0.866 – 1.45 0.367 75 750 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.948 0.883 – 1.02 0.144 972 8317 exclusion phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Symptoms 0.954 0.867 – 1.05 0.335 510 5069 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.998 0.898 – 1.11 0.963 471 4684 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.04 0.95 – 1.14 0.404 672 6717 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.855 0.687 – 1.03 0.0876 223 2230 exclusion phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 0.837 0.728 – 0.961 0.0115 310 3097 exclusion phecode
795.8 Abnormal tumor markers Symptoms 0.871 0.686 – 1.1 0.244 115 1145 exclusion phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 0.865 0.662 – 1.12 0.271 92 912 exclusion phecode
796 Elevated prostate specific antigen [PSA] Symptoms 0.906 0.828 – 0.99 0.0299 785 5994 exclusion phecode
797 Shock Symptoms 0.949 0.826 – 1.09 0.457 274 2730 exclusion phecode
797.1 Cardiogenic shock Symptoms 0.962 0.775 – 1.19 0.717 113 1122 exclusion phecode
798 Malaise and fatigue Symptoms 0.974 0.944 – 1.01 0.102 6070 24586 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1.01 0.88 – 1.16 0.891 272 2700 exclusion phecode
799 Debility unspecified Symptoms 1.06 0.977 – 1.14 0.164 928 9233 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 0.974 0.909 – 1.04 0.45 1078 10737 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.02 0.894 – 1.15 0.81 331 3284 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.922 0.805 – 1.05 0.235 267 2668 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.977 0.882 – 1.08 0.647 468 4662 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.924 0.784 – 1.09 0.341 179 1782 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.984 0.921 – 1.05 0.626 1127 11180 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 0.94 0.86 – 1.03 0.162 627 6238 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.08 0.941 – 1.24 0.269 265 2636 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 1 0.938 – 1.08 0.892 1050 10314 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1.02 0.908 – 1.15 0.705 339 3390 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.952 0.867 – 1.04 0.291 596 5933 exclusion phecode
803.21 Colles' fracture Injuries & Poisonings 0.913 0.776 – 1.07 0.262 211 2095 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.05 0.918 – 1.21 0.452 263 2618 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.972 0.897 – 1.05 0.493 759 7490 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.04 0.948 – 1.15 0.382 545 5436 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 0.943 0.824 – 1.08 0.384 296 2954 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 1 0.948 – 1.06 0.887 1498 14637 exclusion phecode
817 Concussion Injuries & Poisonings 0.997 0.879 – 1.13 0.963 299 2962 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.942 0.889 – 0.987 0.497 139 1380 exclusion phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.971 0.672 – 1.38 0.855 53 525 exclusion phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.03 0.993 – 1.09 0.799 64 640 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.952 0.878 – 1.03 0.23 752 7462 exclusion phecode
830 Dislocation Injuries & Poisonings 1.05 1 – 1.1 0.0369 2168 20638 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 1.04 0.981 – 1.1 0.187 1359 13343 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 1.09 0.968 – 1.22 0.156 339 3375 exclusion phecode
840 Sprains and strains Injuries & Poisonings 1.01 0.97 – 1.05 0.668 3421 25884 exclusion phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 1.09 0.965 – 1.23 0.161 323 3220 exclusion phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 1.01 0.932 – 1.1 0.795 786 7859 exclusion phecode
840.3 Joint/ligament sprain Injuries & Poisonings 1.03 0.956 – 1.11 0.429 822 7524 exclusion phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.936 0.859 – 1.02 0.125 674 6740 exclusion phecode
842 Other sprains and strains Injuries & Poisonings 1.07 0.938 – 1.24 0.143 529 5280 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.997 0.932 – 1.07 0.923 1214 12140 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.01 0.882 – 1.15 0.904 334 3319 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.16 1.01 – 1.35 0.0389 224 2229 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.01 0.934 – 1.1 0.739 758 7566 exclusion phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.05 0.911 – 1.2 0.516 246 2454 exclusion phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.07 0.92 – 1.24 0.368 217 2170 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.08 0.996 – 1.17 0.0628 725 7209 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.963 0.907 – 1.02 0.226 1347 13408 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.02 0.962 – 1.09 0.459 1318 13150 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 0.907 0.695 – 1.17 0.456 85 848 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 0.954 0.904 – 1.01 0.0786 2111 20830 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.833 0.688 – 0.997 0.0496 174 1740 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 0.975 0.675 – 1.38 0.876 65 641 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.946 0.85 – 1.05 0.304 579 5766 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.935 0.853 – 0.989 0.587 124 1227 exclusion phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 0.891 0.731 – 1.08 0.244 147 1470 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.908 0.743 – 1.1 0.33 168 1673 exclusion phecode
870.8 Open wound of genital organs Injuries & Poisonings 0.933 0.668 – 1.29 0.67 61 610 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 0.969 0.915 – 1.03 0.277 1620 16154 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.02 0.886 – 1.17 0.797 264 2640 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.08 0.972 – 1.19 0.154 495 4947 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.08 0.723 – 1.12 0.309 174 1740 exclusion phecode
871.4 Open wound of toe(s) Injuries & Poisonings 0.927 0.736 – 1.16 0.511 103 1030 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.01 0.951 – 1.28 0.876 242 2420 exclusion phecode
873 Broken tooth Injuries & Poisonings 0.96 0.737 – 1.24 0.753 68 663 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.13 0.85 – 1.18 0.277 79 780 exclusion phecode
875 Non-healing surgical wound Injuries & Poisonings 0.972 0.823 – 1.14 0.66 350 3500 exclusion phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.16 1.02 – 1.32 0.0233 297 2950 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 0.974 0.894 – 1.06 0.538 682 6797 exclusion phecode
910 Superficial injury, infected Injuries & Poisonings 0.857 0.62 – 1.17 0.329 59 590 exclusion phecode
911 Blister Injuries & Poisonings 1.07 1 – 1.13 0.595 56 560 exclusion phecode
912 Insect bite Injuries & Poisonings 1.01 0.841 – 1.21 0.9 154 1540 exclusion phecode
913 Toxic effect of venom Injuries & Poisonings 1.05 0.878 – 1.26 0.568 146 1460 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 0.983 0.916 – 1.05 0.63 1040 10341 exclusion phecode
916 Contusion Injuries & Poisonings 0.984 0.934 – 1.04 0.553 1914 19035 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 1.05 0.95 – 1.17 0.321 444 4430 exclusion phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Injuries & Poisonings 0.959 0.847 – 1.08 0.507 333 3318 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.01 0.961 – 1.06 0.66 2959 20675 exclusion phecode
938.1 Acute dermatitis due to solar radiation Injuries & Poisonings 1.14 0.883 – 1.45 0.306 90 898 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 1.01 0.962 – 1.07 0.591 2842 20396 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.971 0.932 – 1.01 0.167 3339 23216 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.03 0.9 – 1.06 0.741 124 1230 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.989 0.857 – 1.03 0.881 168 1680 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.02 0.883 – 1.17 0.797 254 2540 exclusion phecode
947 Urticaria Injuries & Poisonings 0.959 0.874 – 1.05 0.367 590 5884 exclusion phecode
949 Allergies, other Injuries & Poisonings 1 0.952 – 1.06 0.89 1859 16941 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.01 0.843 – 1.2 0.928 163 1621 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.974 0.941 – 1 0.795 51 495 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.01 0.902 – 1.13 0.872 408 4075 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.11 0.87 – 1.42 0.386 92 919 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.03 0.792 – 1.32 0.835 66 656 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.03 0.979 – 1.08 0.269 2104 18862 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.02 0.961 – 1.08 0.533 1466 14384 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.07 0.962 – 1.19 0.209 442 4420 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.983 0.913 – 1.06 0.636 973 9595 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.04 0.923 – 1.17 0.524 371 3695 exclusion phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.01 0.879 – 1.17 0.843 253 2525 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.06 1.01 – 1.12 0.511 124 1233 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.06 0.996 – 1.13 0.0666 1308 13062 exclusion phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.06 0.996 – 1.13 0.0634 1273 12711 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.02 0.844 – 1.22 0.844 159 1590 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.02 0.826 – 1.25 0.862 133 1330 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.951 0.873 – 1.03 0.243 687 6861 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.959 0.896 – 1.03 0.234 1086 10815 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.1 0.962 – 1.15 0.451 54 540 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.997 0.89 – 1.11 0.955 387 3866 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 0.851 0.734 – 0.984 0.0301 241 2401 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.08 0.794 – 1.47 0.607 51 495 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.06 0.9 – 1.25 0.467 177 1762 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.03 0.806 – 1.3 0.825 89 890 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.982 0.927 – 1.04 0.548 1551 14658 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.01 0.94 – 1.09 0.755 959 9559 exclusion phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 0.912 0.824 – 1.01 0.0745 521 5202 exclusion phecode
983
Toxic effect of corrosive aromatics, acids, and
Toxic effect of corrosive aromatics, acids, and caustic alkalis
 Injuries & Poisonings 1.11 0.873 – 1.41 0.376 76 760 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 0.986 0.933 – 1.04 0.631 1897 17875 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 0.993 0.926 – 1.06 0.839 1083 10796 exclusion phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 0.994 0.793 – 1.24 0.954 110 1100 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.01 0.937 – 1.08 0.858 1029 10259 exclusion phecode
994.21 Septic shock Injuries & Poisonings 0.943 0.806 – 1.1 0.456 225 2240 exclusion phecode
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