Plot overview
Signal overview
The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.
Evaluation cohort: Michigan Genomics Initiative (MGI).
PheWAS cohort: UK Biobank (UKB).
This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.
Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.
Plot overview
The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.
| Phecode | Description | Category | OR | 95% CI | P value | Cases | Controls | Analysis | Link |
|---|---|---|---|---|---|---|---|---|---|
| 008 | Intestinal infection | Infectious Diseases | 1.01 | 0.988 – 1.03 | 0.36 | 8932 | 89317 | all | phecode |
| 008.5 | Bacterial enteritis | Infectious Diseases | 1.03 | 0.993 – 1.08 | 0.103 | 2723 | 27227 | all | phecode |
| 008.52 | Intestinal infection due to C. difficile | Infectious Diseases | 1.08 | 0.994 – 1.17 | 0.069 | 656 | 6560 | all | phecode |
| 008.6 | Viral Enteritis | Infectious Diseases | 1.03 | 0.961 – 1.11 | 0.393 | 863 | 8630 | all | phecode |
| 008.7 | Intestinal infection due to protozoa | Infectious Diseases | 1.18 | 0.892 – 1.56 | 0.232 | 53 | 530 | all | phecode |
| 010 | Tuberculosis | Infectious Diseases | 1.03 | 0.882 – 1.21 | 0.683 | 174 | 1740 | all | phecode |
| 038 | Septicemia | Infectious Diseases | 1.01 | 0.981 – 1.05 | 0.425 | 4198 | 41980 | all | phecode |
| 038.1 | Gram negative septicemia | Infectious Diseases | 1.03 | 0.96 – 1.11 | 0.397 | 853 | 8530 | all | phecode |
| 038.2 | Gram positive septicemia | Infectious Diseases | 1.05 | 0.958 – 1.15 | 0.291 | 497 | 4970 | all | phecode |
| 041 | Bacterial infection NOS | Infectious Diseases | 1.01 | 0.991 – 1.03 | 0.329 | 12100 | 120995 | all | phecode |
| 041.1 | Staphylococcus infections | Infectious Diseases | 1.02 | 0.986 – 1.06 | 0.214 | 3131 | 31305 | all | phecode |
| 041.2 | Streptococcus infection | Infectious Diseases | 0.998 | 0.948 – 1.05 | 0.931 | 1639 | 16390 | all | phecode |
| 041.4 | E. coli | Infectious Diseases | 1 | 0.962 – 1.04 | 0.956 | 2724 | 27240 | all | phecode |
| 053 | Herpes zoster | Infectious Diseases | 0.981 | 0.886 – 1.09 | 0.715 | 421 | 4210 | all | phecode |
| 053.1 | Herpes zoster with nervous system complications | Infectious Diseases | 0.991 | 0.801 – 1.22 | 0.931 | 96 | 960 | all | phecode |
| 054 | Herpes simplex | Infectious Diseases | 1.05 | 0.911 – 1.21 | 0.493 | 214 | 2140 | all | phecode |
| 070 | Viral hepatitis | Infectious Diseases | 1.04 | 0.959 – 1.14 | 0.318 | 593 | 5930 | all | phecode |
| 070.1 | Viral hepatitis A | Infectious Diseases | 1.03 | 0.806 – 1.32 | 0.789 | 69 | 690 | all | phecode |
| 070.2 | Viral hepatitis B | Infectious Diseases | 1.1 | 0.917 – 1.31 | 0.306 | 134 | 1340 | all | phecode |
| 070.3 | Viral hepatitis C | Infectious Diseases | 1.03 | 0.908 – 1.18 | 0.614 | 257 | 2570 | all | phecode |
| 071 | Human immunodeficiency virus [HIV] disease | Infectious Diseases | 1.07 | 0.903 – 1.27 | 0.417 | 147 | 1470 | all | phecode |
| 071.1 | HIV infection, symptomatic | Infectious Diseases | 1.12 | 0.92 – 1.35 | 0.26 | 117 | 1170 | all | phecode |
| 078 | Viral warts & HPV | Infectious Diseases | 1.11 | 1.04 – 1.18 | 0.00147 | 1006 | 10060 | all | phecode |
| 079 | Viral infection | Infectious Diseases | 0.992 | 0.953 – 1.03 | 0.67 | 2805 | 28050 | all | phecode |
| 079.1 | Varicella infection | Infectious Diseases | 0.868 | 0.666 – 1.12 | 0.279 | 65 | 650 | all | phecode |
| 079.2 | Infectious mononucleosis | Infectious Diseases | 1.29 | 1.01 – 1.65 | 0.0381 | 69 | 690 | all | phecode |
| 080 | Postoperative infection | Infectious Diseases | 1.02 | 0.985 – 1.05 | 0.325 | 4489 | 44888 | all | phecode |
| 081 |
Infection/inflammation of internal prostheticInfection/inflammation of internal prosthetic device; implant; and graft
|
Infectious Diseases | 1.03 | 0.989 – 1.07 | 0.153 | 2487 | 24870 | all | phecode |
| 090 |
Sexually transmitted infections (not HIV orSexually transmitted infections (not HIV or hepatitis)
|
Infectious Diseases | 1.06 | 0.83 – 1.35 | 0.64 | 73 | 730 | all | phecode |
| 1000 | Burns | Injuries & Poisonings | 0.971 | 0.891 – 1.06 | 0.507 | 582 | 5813 | all | phecode |
| 1001 | Foreign body injury | Injuries & Poisonings | 1.01 | 0.955 – 1.08 | 0.65 | 1231 | 12305 | all | phecode |
| 1002 |
Symptoms concerning nutrition, metabolism, andSymptoms concerning nutrition, metabolism, and development
|
Injuries & Poisonings | 0.989 | 0.962 – 1.02 | 0.456 | 5493 | 54927 | all | phecode |
| 1004 |
Other signs and symptoms involving emotionalOther signs and symptoms involving emotional state
|
Injuries & Poisonings | 0.994 | 0.881 – 1.12 | 0.918 | 301 | 3010 | all | phecode |
| 1005 | Other symptoms | Injuries & Poisonings | 1.01 | 0.959 – 1.07 | 0.651 | 1449 | 14484 | all | phecode |
| 1006 | Crushing injury | Injuries & Poisonings | 0.885 | 0.775 – 1.01 | 0.0676 | 258 | 2580 | all | phecode |
| 1007 | Injury to blood vessels | Injuries & Poisonings | 1.09 | 0.957 – 1.24 | 0.194 | 256 | 2560 | all | phecode |
| 1008 | Crushing or internal injury to organs | Injuries & Poisonings | 1.03 | 0.964 – 1.1 | 0.394 | 1014 | 10140 | all | phecode |
| 1009 | Injury, NOS | Injuries & Poisonings | 1 | 0.979 – 1.02 | 0.901 | 8505 | 85048 | all | phecode |
| 1010 | Other tests | Injuries & Poisonings | 1.02 | 0.988 – 1.04 | 0.275 | 5979 | 59790 | all | phecode |
| 1011 | Complications of surgical and medical procedures | Injuries & Poisonings | 1.02 | 1 – 1.05 | 0.0336 | 9182 | 91820 | all | phecode |
| 1012 | Late effect | Injuries & Poisonings | 0.861 | 0.701 – 1.05 | 0.147 | 106 | 1060 | all | phecode |
| 1013 | Asphyxia and hypoxemia | Injuries & Poisonings | 1.09 | 0.97 – 1.22 | 0.143 | 317 | 3170 | all | phecode |
| 1014 | Effects of heat, cold and air pressure | Injuries & Poisonings | 1.09 | 0.842 – 1.39 | 0.514 | 66 | 660 | all | phecode |
| 1015 | Effects of other external causes | Injuries & Poisonings | 1.02 | 0.985 – 1.05 | 0.288 | 4237 | 42370 | all | phecode |
| 1019 |
Other ill-defined and unknown causes ofOther ill-defined and unknown causes of morbidity and mortality
|
Injuries & Poisonings | 1.01 | 0.99 – 1.02 | 0.433 | 16056 | 160552 | all | phecode |
| 110 | Dermatophytosis / Dermatomycosis | Infectious Diseases | 0.908 | 0.802 – 1.03 | 0.126 | 286 | 2860 | all | phecode |
| 110.1 | Dermatophytosis | Infectious Diseases | 0.903 | 0.796 – 1.02 | 0.112 | 280 | 2800 | all | phecode |
| 110.11 | Dermatophytosis of nail | Infectious Diseases | 0.928 | 0.728 – 1.18 | 0.534 | 76 | 760 | all | phecode |
| 110.12 | Althete's foot | Infectious Diseases | 0.865 | 0.723 – 1.03 | 0.107 | 141 | 1410 | all | phecode |
| 112 | Candidiasis | Infectious Diseases | 1.01 | 0.97 – 1.06 | 0.521 | 2134 | 21340 | all | phecode |
| 117 | Mycoses | Infectious Diseases | 0.958 | 0.845 – 1.09 | 0.505 | 275 | 2750 | all | phecode |
| 117.4 | Aspergillosis | Infectious Diseases | 0.922 | 0.782 – 1.08 | 0.324 | 165 | 1650 | all | phecode |
| 130 | Spirochetal infection | Infectious Diseases | 0.862 | 0.679 – 1.09 | 0.212 | 80 | 800 | all | phecode |
| 133 | Arthropod-borne diseases | Infectious Diseases | 0.932 | 0.724 – 1.19 | 0.572 | 70 | 700 | all | phecode |
| 134 | Helminthiases | Infectious Diseases | 1.32 | 1.1 – 1.57 | 0.00199 | 129 | 1290 | all | phecode |
| 134.1 | Intestinal helminthiases | Infectious Diseases | 1.32 | 1.08 – 1.6 | 0.00506 | 107 | 1070 | all | phecode |
| 136 | Other infectious and parasitic diseases | Infectious Diseases | 1.05 | 0.912 – 1.21 | 0.475 | 207 | 2070 | all | phecode |
| 145 | Cancer of mouth | Neoplasms | 1.04 | 0.961 – 1.13 | 0.31 | 648 | 6480 | all | phecode |
| 145.2 | Cancer of tongue | Neoplasms | 1 | 0.888 – 1.13 | 0.999 | 310 | 3100 | all | phecode |
| 145.3 | Cancer of major salivary glands | Neoplasms | 1.17 | 0.955 – 1.42 | 0.128 | 105 | 1050 | all | phecode |
| 145.5 | Cancer of the mouth floor | Neoplasms | 0.871 | 0.646 – 1.16 | 0.343 | 54 | 540 | all | phecode |
| 149 | Cancer of larynx, pharynx, nasal cavities | Neoplasms | 1.11 | 1.02 – 1.2 | 0.0109 | 643 | 6428 | all | phecode |
| 149.1 | Cancer of oropharynx | Neoplasms | 0.98 | 0.859 – 1.12 | 0.759 | 253 | 2528 | all | phecode |
| 149.4 | Cancer of larynx | Neoplasms | 1.14 | 1 – 1.29 | 0.0446 | 265 | 2648 | all | phecode |
| 149.9 | Cancer of of nasal cavities | Neoplasms | 1.3 | 0.992 – 1.7 | 0.0516 | 57 | 570 | all | phecode |
| 150 | Cancer of esophagus | Neoplasms | 0.983 | 0.911 – 1.06 | 0.646 | 764 | 7640 | all | phecode |
| 151 | Cancer of stomach | Neoplasms | 0.972 | 0.89 – 1.06 | 0.52 | 570 | 5700 | all | phecode |
| 153 | Colorectal cancer | Neoplasms | 1.02 | 0.986 – 1.05 | 0.277 | 4610 | 46100 | all | phecode |
| 153.2 | Colon cancer | Neoplasms | 1.03 | 0.99 – 1.07 | 0.147 | 3109 | 31090 | all | phecode |
| 153.3 |
Malignant neoplasm of rectum, rectosigmoidMalignant neoplasm of rectum, rectosigmoid junction, and anus
|
Neoplasms | 0.994 | 0.951 – 1.04 | 0.792 | 2165 | 21650 | all | phecode |
| 155 | Cancer of liver and intrahepatic bile duct | Neoplasms | 0.993 | 0.895 – 1.1 | 0.897 | 402 | 4020 | all | phecode |
| 155.1 | Malignant neoplasm of liver, primary | Neoplasms | 1.06 | 0.9 – 1.25 | 0.481 | 158 | 1580 | all | phecode |
| 157 | Pancreatic cancer | Neoplasms | 1.01 | 0.93 – 1.09 | 0.832 | 659 | 6590 | all | phecode |
| 158 |
Neoplasm of unspecified nature of digestiveNeoplasm of unspecified nature of digestive system
|
Neoplasms | 1.04 | 0.976 – 1.11 | 0.227 | 1064 | 10640 | all | phecode |
| 159 |
Malignant neoplasm of other and ill-definedMalignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
|
Neoplasms | 1.01 | 0.985 – 1.04 | 0.389 | 5582 | 55820 | all | phecode |
| 159.2 |
Malignant neoplasm of small intestineMalignant neoplasm of small intestine, including duodenum
|
Neoplasms | 1.06 | 0.913 – 1.23 | 0.434 | 189 | 1890 | all | phecode |
| 159.3 |
Malignant neoplasm of gallbladder andMalignant neoplasm of gallbladder and extrahepatic bile ducts
|
Neoplasms | 0.873 | 0.753 – 1.01 | 0.0699 | 205 | 2050 | all | phecode |
| 159.4 |
Malignant neoplasm of retroperitoneum andMalignant neoplasm of retroperitoneum and peritoneum
|
Neoplasms | 0.965 | 0.829 – 1.12 | 0.64 | 192 | 1920 | all | phecode |
| 164 | Cancer of intrathoracic organs | Neoplasms | 1.57 | 1.21 – 2.05 | 0.000629 | 60 | 600 | all | phecode |
| 165 | Cancer within the respiratory system | Neoplasms | 1.07 | 1.03 – 1.11 | 0.00127 | 2833 | 28319 | all | phecode |
| 165.1 | Cancer of bronchus; lung | Neoplasms | 1.06 | 1.02 – 1.11 | 0.00719 | 2238 | 22380 | all | phecode |
| 170 | Cancer of bone and connective tissue | Neoplasms | 1.03 | 0.936 – 1.14 | 0.52 | 445 | 4447 | all | phecode |
| 170.1 | Bone cancer | Neoplasms | 1.12 | 0.935 – 1.34 | 0.213 | 131 | 1310 | all | phecode |
| 170.2 | Cancer of connective tissue | Neoplasms | 1.02 | 0.909 – 1.14 | 0.749 | 331 | 3307 | all | phecode |
| 172 | Skin cancer | Neoplasms | 1.24 | 1.22 – 1.26 | 2.26e-131 | 13624 | 136233 | all | phecode |
| 172.1 | Melanomas of skin, dx or hx | Neoplasms | 1.22 | 1.18 – 1.27 | 2.41e-24 | 2718 | 27180 | all | phecode |
| 172.11 | Melanomas of skin | Neoplasms | 1.22 | 1.18 – 1.27 | 2.41e-24 | 2718 | 27180 | all | phecode |
| 172.2 | Other non-epithelial cancer of skin | Neoplasms | 1.25 | 1.23 – 1.28 | 2.48e-114 | 11030 | 110298 | all | phecode |
| 172.3 | Carcinoma in situ of skin | Neoplasms | 1.37 | 1.27 – 1.48 | 2.92e-15 | 667 | 6670 | all | phecode |
| 173 | Neoplasm of uncertain behavior of skin | Neoplasms | 1.18 | 1.02 – 1.38 | 0.0291 | 182 | 1820 | all | phecode |
| 174 | Breast cancer | Neoplasms | 1.01 | 0.995 – 1.03 | 0.152 | 12771 | 127136 | all | phecode |
| 174.1 | Breast cancer [female] | Neoplasms | 1.01 | 0.996 – 1.03 | 0.128 | 12549 | 124973 | all | phecode |
| 174.11 | Malignant neoplasm of female breast | Neoplasms | 1.02 | 0.999 – 1.04 | 0.0618 | 11767 | 117670 | all | phecode |
| 174.3 | Neoplasm of uncertain behavior of breast | Neoplasms | 0.943 | 0.775 – 1.14 | 0.552 | 115 | 1150 | all | phecode |
| 175 | Acquired absence of breast | Neoplasms | 1.04 | 0.995 – 1.08 | 0.0853 | 2406 | 24060 | all | phecode |
| 180 | Cervical cancer and dysplasia | Neoplasms | 1 | 0.968 – 1.04 | 0.907 | 3640 | 36400 | all | phecode |
| 180.1 | Cervical cancer | Neoplasms | 1.03 | 0.982 – 1.09 | 0.202 | 1655 | 16550 | all | phecode |
| 180.3 |
Cervical intraepithelial neoplasia [CIN]Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
|
Neoplasms | 0.986 | 0.942 – 1.03 | 0.556 | 2081 | 20810 | all | phecode |
| 182 | Malignant neoplasm of uterus | Neoplasms | 0.944 | 0.89 – 1 | 0.0509 | 1288 | 12880 | all | phecode |
| 184 | Cancer of other female genital organs | Neoplasms | 1.02 | 0.978 – 1.06 | 0.365 | 2467 | 24670 | all | phecode |
| 184.1 |
Malignant neoplasm of ovary and other uterineMalignant neoplasm of ovary and other uterine adnexa
|
Neoplasms | 1.04 | 0.993 – 1.09 | 0.101 | 2131 | 21310 | all | phecode |
| 184.11 | Malignant neoplasm of ovary | Neoplasms | 1.04 | 0.989 – 1.08 | 0.133 | 2108 | 21080 | all | phecode |
| 184.2 |
Cancer of other female genital organsCancer of other female genital organs (excluding uterus and ovary)
|
Neoplasms | 0.935 | 0.829 – 1.05 | 0.275 | 305 | 3050 | all | phecode |
| 185 | Cancer of prostate | Neoplasms | 0.996 | 0.971 – 1.02 | 0.729 | 6719 | 64751 | all | phecode |
| 187 | Cancer of other male genital organs | Neoplasms | 0.997 | 0.961 – 1.03 | 0.872 | 3114 | 31140 | all | phecode |
| 187.1 |
Malignant neoplasm of unspecified male genitalMalignant neoplasm of unspecified male genital organ
|
Neoplasms | 0.985 | 0.948 – 1.02 | 0.461 | 2835 | 28350 | all | phecode |
| 187.2 | Malignant neoplasm of testis | Neoplasms | 0.995 | 0.957 – 1.03 | 0.777 | 2973 | 29730 | all | phecode |
| 187.8 |
Neoplasm of uncertain behavior of male genitalNeoplasm of uncertain behavior of male genital organs
|
Neoplasms | 1.09 | 0.891 – 1.32 | 0.406 | 110 | 1100 | all | phecode |
| 189 |
Cancer of urinary organs (incl. kidney andCancer of urinary organs (incl. kidney and bladder)
|
Neoplasms | 1.01 | 0.978 – 1.04 | 0.537 | 4183 | 41830 | all | phecode |
| 189.1 | Cancer of kidney and renal pelvis | Neoplasms | 1 | 0.94 – 1.07 | 0.965 | 1075 | 10750 | all | phecode |
| 189.11 | Malignant neoplasm of kidney, except pelvis | Neoplasms | 0.986 | 0.924 – 1.05 | 0.678 | 1032 | 10320 | all | phecode |
| 189.12 | Malignant neoplasm of renal pelvis | Neoplasms | 1.25 | 0.968 – 1.6 | 0.0805 | 66 | 660 | all | phecode |
| 189.2 | Cancer of bladder | Neoplasms | 1.01 | 0.971 – 1.06 | 0.539 | 2424 | 24240 | all | phecode |
| 189.21 | Malignant neoplasm of bladder | Neoplasms | 0.994 | 0.951 – 1.04 | 0.807 | 2148 | 21480 | all | phecode |
| 189.4 | Malignant neoplasm of other urinary organs | Neoplasms | 1.1 | 0.928 – 1.31 | 0.262 | 144 | 1440 | all | phecode |
| 190 | Cancer of eye | Neoplasms | 1.2 | 1.03 – 1.4 | 0.0178 | 176 | 1760 | all | phecode |
| 191 |
Manlignant and unknown neoplasms of brain andManlignant and unknown neoplasms of brain and nervous system
|
Neoplasms | 0.995 | 0.919 – 1.08 | 0.902 | 692 | 6920 | all | phecode |
| 191.1 | Cancer of brain and nervous system | Neoplasms | 0.979 | 0.897 – 1.07 | 0.632 | 568 | 5680 | all | phecode |
| 191.11 | Cancer of brain | Neoplasms | 0.977 | 0.892 – 1.07 | 0.621 | 524 | 5240 | all | phecode |
| 193 | Thyroid cancer | Neoplasms | 1.14 | 1.02 – 1.26 | 0.0211 | 358 | 3580 | all | phecode |
| 194 | Cancer of other endocrine glands | Neoplasms | 1.01 | 0.813 – 1.24 | 0.956 | 95 | 950 | all | phecode |
| 195 | Cancer, suspected or other | Neoplasms | 1.06 | 1.05 – 1.08 | 3.05e-14 | 17028 | 165982 | all | phecode |
| 195.1 | Malignant neoplasm, other | Neoplasms | 1.07 | 1.05 – 1.08 | 3.99e-15 | 16305 | 159816 | all | phecode |
| 197 | Chemotherapy | Neoplasms | 1.02 | 1.01 – 1.04 | 0.00298 | 21492 | 213706 | all | phecode |
| 198 | Secondary malignant neoplasm | Neoplasms | 1.03 | 1.01 – 1.06 | 0.00201 | 9585 | 95830 | all | phecode |
| 198.1 | Secondary malignancy of lymph nodes | Neoplasms | 1.04 | 1.01 – 1.07 | 0.00342 | 5355 | 53549 | all | phecode |
| 198.2 | Secondary malignancy of respiratory organs | Neoplasms | 1.01 | 0.963 – 1.05 | 0.773 | 2263 | 22619 | all | phecode |
| 198.3 |
Secondary malignant neoplasm of digestiveSecondary malignant neoplasm of digestive systems
|
Neoplasms | 1.02 | 0.965 – 1.07 | 0.525 | 1542 | 15416 | all | phecode |
| 198.4 | Secondary malignant neoplasm of liver | Neoplasms | 1.03 | 0.989 – 1.07 | 0.155 | 2661 | 26602 | all | phecode |
| 198.5 | Secondary malignancy of brain/spine | Neoplasms | 1.05 | 0.979 – 1.13 | 0.167 | 846 | 8460 | all | phecode |
| 198.6 | Secondary malignancy of bone | Neoplasms | 1.03 | 0.986 – 1.08 | 0.18 | 2156 | 21553 | all | phecode |
| 198.7 | Secondary malignant neoplasm of skin | Neoplasms | 1.18 | 1.02 – 1.37 | 0.0251 | 187 | 1869 | all | phecode |
| 199 | Neoplasm of uncertain behavior | Neoplasms | 1.04 | 0.986 – 1.1 | 0.142 | 1433 | 14330 | all | phecode |
| 199.4 | Neurofibromatosis | Neoplasms | 0.858 | 0.689 – 1.06 | 0.161 | 95 | 950 | all | phecode |
| 200 | Myeloproliferative disease | Neoplasms | 1.01 | 0.942 – 1.07 | 0.85 | 1000 | 10000 | all | phecode |
| 200.1 | Polycythemia vera | Neoplasms | 0.997 | 0.898 – 1.11 | 0.956 | 390 | 3900 | all | phecode |
| 201 | Hodgkin's disease | Neoplasms | 0.973 | 0.855 – 1.11 | 0.679 | 261 | 2610 | all | phecode |
| 202 | Cancer of other lymphoid, histiocytic tissue | Neoplasms | 1.01 | 0.963 – 1.05 | 0.792 | 2297 | 22970 | all | phecode |
| 202.2 | Non-Hodgkins lymphoma | Neoplasms | 1 | 0.954 – 1.05 | 0.967 | 1821 | 18210 | all | phecode |
| 202.21 | Nodular lymphoma | Neoplasms | 0.998 | 0.896 – 1.11 | 0.968 | 370 | 3700 | all | phecode |
| 202.24 | Large cell lymphoma | Neoplasms | 1.01 | 0.926 – 1.1 | 0.838 | 584 | 5840 | all | phecode |
| 204 | Leukemia | Neoplasms | 1.03 | 0.98 – 1.08 | 0.246 | 1696 | 16954 | all | phecode |
| 204.1 | Lymphoid leukemia | Neoplasms | 1.08 | 0.99 – 1.17 | 0.0844 | 587 | 5864 | all | phecode |
| 204.11 | Lymphoid leukemia, acute | Neoplasms | 0.943 | 0.718 – 1.23 | 0.659 | 60 | 600 | all | phecode |
| 204.12 | Lymphoid leukemia, chronic | Neoplasms | 1.07 | 0.98 – 1.18 | 0.127 | 514 | 5134 | all | phecode |
| 204.2 | Myeloid leukemia | Neoplasms | 0.966 | 0.879 – 1.06 | 0.477 | 486 | 4860 | all | phecode |
| 204.21 | Myeloid leukemia, acute | Neoplasms | 0.987 | 0.881 – 1.11 | 0.827 | 336 | 3360 | all | phecode |
| 204.22 | Myeloid leukemia, chronic | Neoplasms | 0.936 | 0.792 – 1.1 | 0.433 | 157 | 1570 | all | phecode |
| 204.4 | Multiple myeloma | Neoplasms | 1.07 | 0.979 – 1.16 | 0.138 | 559 | 5590 | all | phecode |
| 208 | Benign neoplasm of colon | Neoplasms | 1.03 | 1.02 – 1.05 | 5.66e-05 | 19890 | 192225 | all | phecode |
| 210 | Benign neoplasm of lip, oral cavity, and pharynx | Neoplasms | 1.04 | 0.97 – 1.11 | 0.29 | 981 | 9810 | all | phecode |
| 211 |
Benign neoplasm of other parts of digestiveBenign neoplasm of other parts of digestive system
|
Neoplasms | 1.01 | 0.98 – 1.04 | 0.547 | 5256 | 52560 | all | phecode |
| 212 |
Benign neoplasm of respiratory andBenign neoplasm of respiratory and intrathoracic organs
|
Neoplasms | 1.02 | 0.911 – 1.14 | 0.747 | 348 | 3480 | all | phecode |
| 213 | Benign neoplasm of bone and articular cartilage | Neoplasms | 1.16 | 1.03 – 1.3 | 0.0111 | 320 | 3200 | all | phecode |
| 214 | Lipoma | Neoplasms | 1 | 0.974 – 1.03 | 0.994 | 6246 | 62460 | all | phecode |
| 214.1 | Lipoma of skin and subcutaneous tissue | Neoplasms | 1 | 0.973 – 1.03 | 0.855 | 4593 | 45930 | all | phecode |
| 215 |
Other benign neoplasm of connective and otherOther benign neoplasm of connective and other soft tissue
|
Neoplasms | 1.01 | 0.952 – 1.08 | 0.671 | 1109 | 11090 | all | phecode |
| 216 | Benign neoplasm of skin | Neoplasms | 0.971 | 0.948 – 0.994 | 0.0139 | 7679 | 76785 | all | phecode |
| 217 | Vascular hamartomas and non-neoplastic nevi | Neoplasms | 1.03 | 0.95 – 1.12 | 0.457 | 649 | 6490 | all | phecode |
| 217.1 | Nevus, non-neoplastic | Neoplasms | 1.01 | 0.924 – 1.1 | 0.888 | 597 | 5970 | all | phecode |
| 218 | Benign neoplasm of uterus | Neoplasms | 1.01 | 0.99 – 1.03 | 0.315 | 10507 | 105069 | all | phecode |
| 218.1 | Uterine leiomyoma | Neoplasms | 1.01 | 0.992 – 1.03 | 0.24 | 10245 | 102449 | all | phecode |
| 218.2 | Other benign neoplasm of uterus | Neoplasms | 0.949 | 0.849 – 1.06 | 0.352 | 353 | 3530 | all | phecode |
| 220 | Benign neoplasm of ovary | Neoplasms | 1.05 | 1 – 1.11 | 0.0505 | 1476 | 14760 | all | phecode |
| 221 | Benign neoplasm of other female genital organs | Neoplasms | 1.09 | 0.948 – 1.25 | 0.221 | 220 | 2200 | all | phecode |
| 222 | Benign neoplasm of male genital organs | Neoplasms | 0.876 | 0.741 – 1.03 | 0.115 | 160 | 1600 | all | phecode |
| 223 |
Benign neoplasm of kidney and other urinaryBenign neoplasm of kidney and other urinary organs
|
Neoplasms | 1.02 | 0.87 – 1.19 | 0.803 | 174 | 1740 | all | phecode |
| 224 | Benign neoplasm of eye | Neoplasms | 1.1 | 0.918 – 1.32 | 0.294 | 130 | 1300 | all | phecode |
| 224.1 | Benign neoplasm of eye, uveal | Neoplasms | 1.23 | 0.96 – 1.57 | 0.0935 | 68 | 680 | all | phecode |
| 225 |
Benign neoplasm of brain and other parts ofBenign neoplasm of brain and other parts of nervous system
|
Neoplasms | 1.01 | 0.943 – 1.09 | 0.72 | 830 | 8300 | all | phecode |
| 225.1 |
Benign neoplasm of brain, cranial nervesBenign neoplasm of brain, cranial nerves, meninges
|
Neoplasms | 1.02 | 0.942 – 1.09 | 0.69 | 776 | 7760 | all | phecode |
| 225.2 | Benign neoplasm of spinal cord, meninges | Neoplasms | 0.998 | 0.759 – 1.3 | 0.986 | 59 | 590 | all | phecode |
| 226 | Benign neoplasm of thyroid glands | Neoplasms | 1.01 | 0.897 – 1.15 | 0.814 | 285 | 2850 | all | phecode |
| 227 |
Benign neoplasm of other endocrine glands andBenign neoplasm of other endocrine glands and related structures
|
Neoplasms | 1.06 | 0.986 – 1.13 | 0.119 | 878 | 8780 | all | phecode |
| 227.1 | Benign neoplasm of adrenal gland | Neoplasms | 1.07 | 0.916 – 1.24 | 0.406 | 186 | 1860 | all | phecode |
| 227.2 | Benign neoplasm of parathyroid gland | Neoplasms | 1.12 | 1 – 1.24 | 0.0391 | 371 | 3710 | all | phecode |
| 227.3 |
Benign neoplasm of pituitary gland andBenign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
|
Neoplasms | 0.989 | 0.879 – 1.11 | 0.859 | 311 | 3110 | all | phecode |
| 228 | Hemangioma and lymphangioma, any site | Neoplasms | 1.03 | 0.974 – 1.08 | 0.338 | 1602 | 16020 | all | phecode |
| 229 | Benign neoplasm of unspecified sites | Neoplasms | 0.899 | 0.861 – 0.938 | 1.02e-06 | 2400 | 23998 | all | phecode |
| 240 | Simple and unspecified goiter | Endocrine/metabolic | 0.987 | 0.907 – 1.07 | 0.762 | 602 | 6020 | all | phecode |
| 241 | Nontoxic nodular goiter | Endocrine/metabolic | 0.984 | 0.925 – 1.05 | 0.613 | 1142 | 11420 | all | phecode |
| 241.1 | Nontoxic uninodular goiter | Endocrine/metabolic | 0.931 | 0.845 – 1.02 | 0.142 | 472 | 4720 | all | phecode |
| 241.2 | Nontoxic multinodular goiter | Endocrine/metabolic | 1.04 | 0.956 – 1.12 | 0.395 | 679 | 6790 | all | phecode |
| 242 | Thyrotoxicosis with or without goiter | Endocrine/metabolic | 1.01 | 0.965 – 1.06 | 0.601 | 1849 | 18490 | all | phecode |
| 242.1 | Graves' disease | Endocrine/metabolic | 0.997 | 0.904 – 1.1 | 0.947 | 456 | 4560 | all | phecode |
| 242.2 | Toxic multinodular goiter | Endocrine/metabolic | 1.24 | 1 – 1.53 | 0.0415 | 91 | 910 | all | phecode |
| 242.3 | Exophthalmos | Endocrine/metabolic | 0.944 | 0.785 – 1.13 | 0.535 | 129 | 1290 | all | phecode |
| 244 | Hypothyroidism | Endocrine/metabolic | 0.998 | 0.981 – 1.01 | 0.783 | 14646 | 145476 | all | phecode |
| 244.1 | Secondary hypothyroidism | Endocrine/metabolic | 1.03 | 0.971 – 1.1 | 0.298 | 1111 | 11110 | all | phecode |
| 244.2 | Acquired hypothyroidism | Endocrine/metabolic | 1.17 | 0.951 – 1.43 | 0.134 | 101 | 1010 | all | phecode |
| 244.4 | Hypothyroidism NOS | Endocrine/metabolic | 0.994 | 0.977 – 1.01 | 0.505 | 13961 | 139245 | all | phecode |
| 245 | Thyroiditis | Endocrine/metabolic | 0.953 | 0.843 – 1.08 | 0.438 | 294 | 2940 | all | phecode |
| 245.2 | Chronic thyroiditis | Endocrine/metabolic | 0.979 | 0.851 – 1.12 | 0.763 | 224 | 2240 | all | phecode |
| 245.21 | Chronic lymphocytic thyroiditis | Endocrine/metabolic | 0.962 | 0.833 – 1.11 | 0.598 | 211 | 2110 | all | phecode |
| 246 | Other disorders of thyroid | Endocrine/metabolic | 0.991 | 0.894 – 1.1 | 0.868 | 403 | 4030 | all | phecode |
| 250 | Diabetes mellitus | Endocrine/metabolic | 1.02 | 1 – 1.03 | 0.0196 | 19898 | 186647 | all | phecode |
| 250.1 | Type 1 diabetes | Endocrine/metabolic | 1.03 | 0.989 – 1.07 | 0.155 | 2657 | 26570 | all | phecode |
| 250.11 | Type 1 diabetes with ketoacidosis | Endocrine/metabolic | 0.989 | 0.864 – 1.13 | 0.87 | 239 | 2390 | all | phecode |
| 250.12 | Type 1 diabetes with renal manifestations | Endocrine/metabolic | 1.01 | 0.795 – 1.27 | 0.946 | 77 | 770 | all | phecode |
| 250.2 | Type 2 diabetes | Endocrine/metabolic | 1.02 | 1 – 1.03 | 0.0284 | 18671 | 176412 | all | phecode |
| 250.21 | Type 2 diabetes with ketoacidosis | Endocrine/metabolic | 1.09 | 0.894 – 1.34 | 0.372 | 105 | 1050 | all | phecode |
| 250.22 | Type 2 diabetes with renal manifestations | Endocrine/metabolic | 1.08 | 0.934 – 1.25 | 0.297 | 202 | 2020 | all | phecode |
| 250.23 | Type 2 diabetes with ophthalmic manifestations | Endocrine/metabolic | 1.02 | 0.964 – 1.08 | 0.471 | 1294 | 12940 | all | phecode |
| 250.24 | Type 2 diabetes with neurological manifestations | Endocrine/metabolic | 1.09 | 0.996 – 1.18 | 0.0587 | 575 | 5750 | all | phecode |
| 250.4 | Abnormal glucose | Endocrine/metabolic | 0.977 | 0.902 – 1.06 | 0.567 | 684 | 6840 | all | phecode |
| 250.41 | Impaired fasting glucose | Endocrine/metabolic | 0.992 | 0.872 – 1.13 | 0.908 | 266 | 2660 | all | phecode |
| 250.42 | Other abnormal glucose | Endocrine/metabolic | 0.983 | 0.888 – 1.09 | 0.746 | 419 | 4190 | all | phecode |
| 250.5 | Glycosuria or Acetonuria | Endocrine/metabolic | 1.02 | 0.845 – 1.22 | 0.864 | 131 | 1310 | all | phecode |
| 250.6 | Polyneuropathy in diabetes | Endocrine/metabolic | 1.06 | 0.953 – 1.19 | 0.271 | 354 | 3540 | all | phecode |
| 250.7 | Diabetic retinopathy | Endocrine/metabolic | 1 | 0.949 – 1.06 | 0.87 | 1335 | 13350 | all | phecode |
| 251.1 | Hypoglycemia | Endocrine/metabolic | 1.05 | 0.977 – 1.12 | 0.197 | 940 | 9395 | all | phecode |
| 252 | Disorders of parathyroid gland | Endocrine/metabolic | 1.03 | 0.959 – 1.1 | 0.432 | 877 | 8770 | all | phecode |
| 252.1 | Hyperparathyroidism | Endocrine/metabolic | 1.03 | 0.952 – 1.1 | 0.505 | 781 | 7810 | all | phecode |
| 252.2 | Hypoparathyroidism | Endocrine/metabolic | 1.04 | 0.87 – 1.23 | 0.687 | 142 | 1420 | all | phecode |
| 253 |
Disorders of the pituitary gland and itsDisorders of the pituitary gland and its hypothalamic control
|
Endocrine/metabolic | 1.02 | 0.946 – 1.11 | 0.561 | 694 | 6940 | all | phecode |
| 253.1 | Pituitary hyperfunction | Endocrine/metabolic | 0.928 | 0.796 – 1.08 | 0.331 | 189 | 1890 | all | phecode |
| 253.11 | Acromegaly and gigantism | Endocrine/metabolic | 0.965 | 0.778 – 1.19 | 0.737 | 95 | 950 | all | phecode |
| 253.2 | Pituitary hypofunction | Endocrine/metabolic | 1.07 | 0.942 – 1.22 | 0.295 | 263 | 2630 | all | phecode |
| 253.3 | Diabetes insipidus | Endocrine/metabolic | 1.22 | 0.988 – 1.51 | 0.0608 | 93 | 930 | all | phecode |
| 253.7 | Other disorders of neurohypophysis | Endocrine/metabolic | 0.995 | 0.842 – 1.17 | 0.95 | 158 | 1580 | all | phecode |
| 255 | Disorders of adrenal glands | Endocrine/metabolic | 0.963 | 0.887 – 1.05 | 0.368 | 642 | 6420 | all | phecode |
| 255.1 | Adrenal hyperfunction | Endocrine/metabolic | 1.09 | 0.938 – 1.27 | 0.247 | 182 | 1820 | all | phecode |
| 255.11 | Cushing's syndrome | Endocrine/metabolic | 1.04 | 0.848 – 1.27 | 0.694 | 103 | 1030 | all | phecode |
| 255.12 | Hyperaldosteronism | Endocrine/metabolic | 1.16 | 0.918 – 1.46 | 0.203 | 76 | 760 | all | phecode |
| 255.2 | Adrenal hypofunction | Endocrine/metabolic | 0.927 | 0.83 – 1.03 | 0.174 | 364 | 3640 | all | phecode |
| 255.21 | Glucocorticoid deficiency | Endocrine/metabolic | 0.921 | 0.824 – 1.03 | 0.143 | 361 | 3610 | all | phecode |
| 256 | Ovarian dysfunction | Endocrine/metabolic | 0.926 | 0.809 – 1.06 | 0.254 | 244 | 2440 | all | phecode |
| 256.4 | Polycystic ovaries | Endocrine/metabolic | 0.922 | 0.798 – 1.06 | 0.268 | 209 | 2090 | all | phecode |
| 257 | Testicular dysfunction | Endocrine/metabolic | 1.13 | 0.963 – 1.33 | 0.129 | 163 | 1630 | all | phecode |
| 257.1 | Testicular hypofunction | Endocrine/metabolic | 1.11 | 0.942 – 1.31 | 0.204 | 154 | 1540 | all | phecode |
| 258 | Iatrogenic endocrine disorders | Endocrine/metabolic | 1.03 | 0.836 – 1.26 | 0.779 | 102 | 1020 | all | phecode |
| 259 | Other endocrine disorders | Endocrine/metabolic | 1.1 | 0.936 – 1.3 | 0.233 | 152 | 1520 | all | phecode |
| 260 | Protein-calorie malnutrition | Endocrine/metabolic | 1.11 | 0.96 – 1.28 | 0.156 | 202 | 2019 | all | phecode |
| 261 | Vitamin deficiency | Endocrine/metabolic | 1.04 | 0.981 – 1.11 | 0.179 | 1210 | 12100 | all | phecode |
| 261.2 | Vitamin B-complex deficiencies | Endocrine/metabolic | 1.01 | 0.94 – 1.09 | 0.725 | 755 | 7550 | all | phecode |
| 261.4 | Vitamin D deficiency | Endocrine/metabolic | 1.05 | 0.952 – 1.16 | 0.33 | 449 | 4490 | all | phecode |
| 261.41 | Rickets or osteomalacia | Endocrine/metabolic | 0.902 | 0.707 – 1.14 | 0.393 | 77 | 770 | all | phecode |
| 262 | Mineral deficiency NEC | Endocrine/metabolic | 1.01 | 0.884 – 1.15 | 0.884 | 242 | 2420 | all | phecode |
| 269 | Proteinuria | Endocrine/metabolic | 1 | 0.895 – 1.12 | 0.971 | 339 | 3390 | all | phecode |
| 270 |
Disorders of protein plasma/amino-acidDisorders of protein plasma/amino-acid transport and metabolism
|
Endocrine/metabolic | 1.03 | 0.91 – 1.15 | 0.673 | 304 | 3040 | all | phecode |
| 270.3 | Disorders of plasma protein metabolism | Endocrine/metabolic | 1.01 | 0.892 – 1.15 | 0.824 | 261 | 2610 | all | phecode |
| 270.32 | Paraproteinemia | Endocrine/metabolic | 1 | 0.863 – 1.17 | 0.957 | 191 | 1910 | all | phecode |
| 270.35 | Macroglobulinemia | Endocrine/metabolic | 1.01 | 0.782 – 1.29 | 0.961 | 69 | 690 | all | phecode |
| 271 |
Disorders of carbohydrate transport andDisorders of carbohydrate transport and metabolism
|
Endocrine/metabolic | 0.981 | 0.834 – 1.15 | 0.817 | 163 | 1621 | all | phecode |
| 271.3 |
Intestinal disaccharidase deficiencies andIntestinal disaccharidase deficiencies and disaccharide malabsorption
|
Endocrine/metabolic | 0.932 | 0.782 – 1.11 | 0.426 | 141 | 1401 | all | phecode |
| 272 | Disorders of lipoid metabolism | Endocrine/metabolic | 1 | 0.993 – 1.02 | 0.407 | 34960 | 235908 | all | phecode |
| 272.1 | Hyperlipidemia | Endocrine/metabolic | 1 | 0.993 – 1.02 | 0.4 | 34878 | 235352 | all | phecode |
| 272.11 | Hypercholesterolemia | Endocrine/metabolic | 1.01 | 0.994 – 1.02 | 0.328 | 32352 | 218140 | all | phecode |
| 272.12 | Hyperglyceridemia | Endocrine/metabolic | 1.06 | 0.807 – 1.39 | 0.654 | 58 | 580 | all | phecode |
| 272.13 | Mixed hyperlipidemia | Endocrine/metabolic | 0.889 | 0.752 – 1.05 | 0.159 | 164 | 1638 | all | phecode |
| 272.9 | Unspecified disorder of lipoid metabolism | Endocrine/metabolic | 1.07 | 0.929 – 1.23 | 0.334 | 211 | 2110 | all | phecode |
| 274 | Gout and other crystal arthropathies | Endocrine/metabolic | 1.02 | 0.983 – 1.05 | 0.319 | 3742 | 37420 | all | phecode |
| 274.1 | Gout | Endocrine/metabolic | 1.02 | 0.983 – 1.06 | 0.295 | 3176 | 31760 | all | phecode |
| 274.11 | Gouty arthropathy | Endocrine/metabolic | 1.2 | 0.985 – 1.45 | 0.0673 | 111 | 1110 | all | phecode |
| 274.2 | Crystal arthropathies | Endocrine/metabolic | 1.01 | 0.924 – 1.09 | 0.906 | 614 | 6140 | all | phecode |
| 274.21 | Chondrocalcinosis | Endocrine/metabolic | 0.998 | 0.914 – 1.09 | 0.959 | 559 | 5590 | all | phecode |
| 275 | Disorders of mineral metabolism | Endocrine/metabolic | 1.03 | 0.98 – 1.07 | 0.276 | 2116 | 21160 | all | phecode |
| 275.1 | Disorders of iron metabolism | Hematopoietic | 1.02 | 0.944 – 1.11 | 0.561 | 657 | 6570 | all | phecode |
| 275.3 | Disorders of magnesium metabolism | Endocrine/metabolic | 1.01 | 0.905 – 1.12 | 0.875 | 374 | 3740 | all | phecode |
| 275.5 | Disorders of calcium/phosphorus metabolism | Endocrine/metabolic | 1.04 | 0.975 – 1.1 | 0.257 | 1205 | 12050 | all | phecode |
| 275.53 | Disorders of phosphorus metabolism | Endocrine/metabolic | 1.07 | 0.917 – 1.25 | 0.376 | 172 | 1720 | all | phecode |
| 276 |
Disorders of fluid, electrolyte, and acid-baseDisorders of fluid, electrolyte, and acid-base balance
|
Endocrine/metabolic | 1.02 | 1 – 1.05 | 0.0488 | 7342 | 73420 | all | phecode |
| 276.1 | Electrolyte imbalance | Endocrine/metabolic | 1.03 | 1 – 1.07 | 0.0462 | 4113 | 41130 | all | phecode |
| 276.11 | Hyperosmolality and/or hypernatremia | Endocrine/metabolic | 1.07 | 0.939 – 1.23 | 0.294 | 239 | 2390 | all | phecode |
| 276.12 | Hyposmolality and/or hyponatremia | Endocrine/metabolic | 1.04 | 0.993 – 1.09 | 0.0959 | 1822 | 18220 | all | phecode |
| 276.13 | Hyperpotassemia | Endocrine/metabolic | 0.999 | 0.935 – 1.07 | 0.977 | 977 | 9770 | all | phecode |
| 276.14 | Hypopotassemia | Endocrine/metabolic | 1.05 | 0.991 – 1.11 | 0.103 | 1422 | 14220 | all | phecode |
| 276.4 | Acid-base balance disorder | Endocrine/metabolic | 1.02 | 0.962 – 1.09 | 0.473 | 1160 | 11600 | all | phecode |
| 276.41 | Acidosis | Endocrine/metabolic | 1.04 | 0.976 – 1.11 | 0.219 | 1059 | 10590 | all | phecode |
| 276.42 | Alkalosis | Endocrine/metabolic | 0.868 | 0.711 – 1.06 | 0.157 | 112 | 1120 | all | phecode |
| 276.5 | Hypovolemia | Endocrine/metabolic | 1.02 | 0.982 – 1.06 | 0.302 | 2825 | 28250 | all | phecode |
| 276.6 | Fluid overload | Endocrine/metabolic | 0.979 | 0.887 – 1.08 | 0.665 | 455 | 4550 | all | phecode |
| 277 | Other disorders of metabolism | Endocrine/metabolic | 1.07 | 1 – 1.15 | 0.0473 | 905 | 9048 | all | phecode |
| 277.5 | Other disorders of lipoid metabolism | Endocrine/metabolic | 0.904 | 0.706 – 1.15 | 0.407 | 75 | 750 | all | phecode |
| 277.51 | Lipoprotein disorders | Endocrine/metabolic | 0.938 | 0.7 – 1.25 | 0.656 | 52 | 520 | all | phecode |
| 278 | Overweight, obesity and other hyperalimentation | Endocrine/metabolic | 1.02 | 1 – 1.04 | 0.0322 | 10863 | 108629 | all | phecode |
| 278.1 | Obesity | Endocrine/metabolic | 1.02 | 1 – 1.04 | 0.0303 | 10696 | 106959 | all | phecode |
| 278.3 | Localized adiposity | Endocrine/metabolic | 0.895 | 0.708 – 1.12 | 0.34 | 83 | 830 | all | phecode |
| 278.4 | Abnormal weight gain | Endocrine/metabolic | 1.05 | 0.812 – 1.35 | 0.71 | 66 | 660 | all | phecode |
| 279 | Disorders involving the immune mechanism | Endocrine/metabolic | 0.951 | 0.833 – 1.08 | 0.453 | 252 | 2520 | all | phecode |
| 279.1 | Immunity deficiency | Endocrine/metabolic | 0.982 | 0.85 – 1.13 | 0.803 | 211 | 2110 | all | phecode |
| 279.11 | Deficiency of humoral immunity | Endocrine/metabolic | 1.02 | 0.855 – 1.21 | 0.82 | 140 | 1400 | all | phecode |
| 280 | Iron deficiency anemias | Hematopoietic | 1.03 | 1 – 1.05 | 0.0202 | 7750 | 77478 | all | phecode |
| 280.1 |
Iron deficiency anemias, unspecified or not dueIron deficiency anemias, unspecified or not due to blood loss
|
Hematopoietic | 1.02 | 1 – 1.05 | 0.046 | 7378 | 73758 | all | phecode |
| 280.2 |
Iron deficiency anemia secondary to blood lossIron deficiency anemia secondary to blood loss (chronic)
|
Hematopoietic | 1.14 | 1.04 – 1.25 | 0.00727 | 455 | 4550 | all | phecode |
| 281 | Other deficiency anemia | Hematopoietic | 1.08 | 1.02 – 1.15 | 0.0132 | 1131 | 11310 | all | phecode |
| 281.1 | Megaloblastic anemia | Hematopoietic | 1.08 | 1.02 – 1.15 | 0.0116 | 1074 | 10740 | all | phecode |
| 281.11 | Pernicious anemia | Hematopoietic | 1.09 | 1.01 – 1.17 | 0.0326 | 752 | 7520 | all | phecode |
| 281.12 | Other vitamin B12 deficiency anemia | Hematopoietic | 0.974 | 0.832 – 1.14 | 0.743 | 178 | 1780 | all | phecode |
| 281.13 | Folate-deficiency anemia | Hematopoietic | 1.15 | 0.984 – 1.33 | 0.0774 | 186 | 1860 | all | phecode |
| 281.9 | Deficiency anemias | Hematopoietic | 1.03 | 0.779 – 1.37 | 0.809 | 54 | 540 | all | phecode |
| 282 | Hereditary hemolytic anemias | Hematopoietic | 0.891 | 0.752 – 1.05 | 0.177 | 157 | 1570 | all | phecode |
| 282.8 | Other hemoglobinopathies | Hematopoietic | 0.926 | 0.697 – 1.22 | 0.583 | 56 | 560 | all | phecode |
| 282.9 | Other hereditary hemolytic anemias | Hematopoietic | 0.865 | 0.686 – 1.08 | 0.208 | 85 | 850 | all | phecode |
| 283 | Acquired hemolytic anemias | Hematopoietic | 1.01 | 0.847 – 1.2 | 0.92 | 143 | 1430 | all | phecode |
| 283.1 | Autoimmune hemolytic anemias | Hematopoietic | 0.994 | 0.81 – 1.21 | 0.951 | 107 | 1070 | all | phecode |
| 284 | Aplastic anemia | Hematopoietic | 1.02 | 0.926 – 1.13 | 0.663 | 440 | 4400 | all | phecode |
| 285 | Other anemias | Hematopoietic | 1.02 | 1.01 – 1.04 | 0.0128 | 12138 | 121369 | all | phecode |
| 285.1 | Acute posthemorrhagic anemia | Hematopoietic | 0.967 | 0.85 – 1.1 | 0.6 | 269 | 2690 | all | phecode |
| 285.2 | Anemia of chronic disease | Hematopoietic | 1.07 | 0.993 – 1.16 | 0.0719 | 693 | 6930 | all | phecode |
| 285.22 | Anemia in neoplastic disease | Hematopoietic | 1.1 | 0.99 – 1.21 | 0.0752 | 412 | 4120 | all | phecode |
| 286 | Coagulation defects | Hematopoietic | 1 | 0.938 – 1.07 | 0.902 | 929 | 9290 | all | phecode |
| 286.1 | Congenital coagulation defects | Hematopoietic | 1 | 0.907 – 1.1 | 0.993 | 460 | 4600 | all | phecode |
| 286.11 | Von willebrand's disease | Hematopoietic | 0.931 | 0.749 – 1.15 | 0.509 | 96 | 960 | all | phecode |
| 286.12 |
Congenital deficiency of other clotting factorsCongenital deficiency of other clotting factors (including factor VII)
|
Hematopoietic | 1.04 | 0.918 – 1.17 | 0.56 | 294 | 2940 | all | phecode |
| 286.13 | Congenital factor VIII disorder | Hematopoietic | 1.05 | 0.808 – 1.35 | 0.714 | 63 | 630 | all | phecode |
| 286.5 |
Hemorrhagic disorder due to intrinsicHemorrhagic disorder due to intrinsic circulating anticoagulants
|
Hematopoietic | 1.07 | 0.859 – 1.33 | 0.524 | 85 | 850 | all | phecode |
| 286.7 | Other and unspecified coagulation defects | Hematopoietic | 1.02 | 0.916 – 1.13 | 0.74 | 387 | 3870 | all | phecode |
| 287 | Purpura and other hemorrhagic conditions | Hematopoietic | 1.01 | 0.962 – 1.06 | 0.631 | 1684 | 16840 | all | phecode |
| 287.2 | Allergic purpura | Hematopoietic | 0.896 | 0.666 – 1.2 | 0.455 | 51 | 510 | all | phecode |
| 287.3 | Thrombocytopenia | Hematopoietic | 1.01 | 0.955 – 1.06 | 0.797 | 1566 | 15660 | all | phecode |
| 287.31 | Primary thrombocytopenia | Hematopoietic | 1.02 | 0.921 – 1.13 | 0.704 | 421 | 4210 | all | phecode |
| 287.32 | Secondary thrombocytopenia | Hematopoietic | 1.08 | 0.846 – 1.36 | 0.541 | 75 | 750 | all | phecode |
| 288 | Diseases of white blood cells | Hematopoietic | 1.02 | 0.983 – 1.05 | 0.331 | 3795 | 37950 | all | phecode |
| 288.1 | Decreased white blood cell count | Hematopoietic | 1.01 | 0.97 – 1.04 | 0.732 | 3192 | 31920 | all | phecode |
| 288.11 | Neutropenia | Hematopoietic | 1.01 | 0.97 – 1.04 | 0.732 | 3192 | 31920 | all | phecode |
| 288.3 | Eosinophilia | Hematopoietic | 1.06 | 0.83 – 1.35 | 0.614 | 71 | 710 | all | phecode |
| 289 | Other diseases of blood and blood-forming organs | Hematopoietic | 1.11 | 1.03 – 1.19 | 0.00476 | 868 | 8680 | all | phecode |
| 289.3 |
Personal history of diseases of blood andPersonal history of diseases of blood and blood-forming organs
|
Hematopoietic | 1.15 | 1.02 – 1.3 | 0.0187 | 291 | 2910 | all | phecode |
| 289.9 | Abnormality of red blood cells | Hematopoietic | 1.03 | 0.826 – 1.28 | 0.796 | 90 | 900 | all | phecode |
| 290 |
Delirium dementia and amnestic and otherDelirium dementia and amnestic and other cognitive disorders
|
Mental Disorders | 1.07 | 1.02 – 1.13 | 0.00273 | 1949 | 19490 | all | phecode |
| 290.1 | Dementias | Mental Disorders | 1.07 | 1 – 1.14 | 0.0357 | 1006 | 10060 | all | phecode |
| 290.11 | Alzheimer's disease | Mental Disorders | 1.06 | 0.964 – 1.17 | 0.212 | 433 | 4330 | all | phecode |
| 290.16 | Vascular dementia | Mental Disorders | 1.18 | 1.02 – 1.36 | 0.0247 | 201 | 2010 | all | phecode |
| 290.2 | Delirium due to conditions classified elsewhere | Mental Disorders | 1.07 | 0.989 – 1.16 | 0.0906 | 651 | 6510 | all | phecode |
| 291 |
Other specified nonpsychotic and/or transientOther specified nonpsychotic and/or transient mental disorders
|
Mental Disorders | 1.1 | 1.02 – 1.2 | 0.0181 | 638 | 6380 | all | phecode |
| 291.1 |
Transient mental disorders due to conditionsTransient mental disorders due to conditions classified elsewhere
|
Mental Disorders | 0.934 | 0.77 – 1.13 | 0.479 | 121 | 1210 | all | phecode |
| 291.4 |
Specific nonpsychotic mental disorders due toSpecific nonpsychotic mental disorders due to brain damage
|
Mental Disorders | 1.16 | 0.93 – 1.45 | 0.178 | 85 | 850 | all | phecode |
| 291.8 | Alteration of consciousness | Mental Disorders | 1.14 | 1.03 – 1.25 | 0.0112 | 437 | 4370 | all | phecode |
| 292 | Neurological disorders | Mental Disorders | 1.01 | 0.983 – 1.04 | 0.405 | 4645 | 46450 | all | phecode |
| 292.1 | Aphasia/speech disturbance | Mental Disorders | 1.01 | 0.957 – 1.06 | 0.731 | 1507 | 15070 | all | phecode |
| 292.2 | Mild cognitive impairment | Mental Disorders | 1.01 | 0.865 – 1.17 | 0.934 | 190 | 1900 | all | phecode |
| 292.3 | Memory loss | Mental Disorders | 1 | 0.926 – 1.08 | 0.969 | 700 | 7000 | all | phecode |
| 292.4 | Altered mental status | Mental Disorders | 0.991 | 0.948 – 1.04 | 0.693 | 2185 | 21850 | all | phecode |
| 292.6 | Hallucinations | Mental Disorders | 1.07 | 0.955 – 1.21 | 0.229 | 308 | 3080 | all | phecode |
| 293 | Symptoms involving head and neck | Mental Disorders | 1.03 | 0.986 – 1.08 | 0.173 | 2082 | 20820 | all | phecode |
| 295 | Schizophrenia and other psychotic disorders | Mental Disorders | 0.969 | 0.902 – 1.04 | 0.38 | 851 | 8510 | all | phecode |
| 295.1 | Schizophrenia | Mental Disorders | 0.98 | 0.898 – 1.07 | 0.645 | 572 | 5720 | all | phecode |
| 295.2 | Paranoid disorders | Mental Disorders | 0.972 | 0.831 – 1.13 | 0.715 | 179 | 1790 | all | phecode |
| 295.3 | Psychosis | Mental Disorders | 0.911 | 0.776 – 1.07 | 0.254 | 171 | 1710 | all | phecode |
| 296 | Mood disorders | Mental Disorders | 1.02 | 1 – 1.04 | 0.0317 | 12461 | 124609 | all | phecode |
| 296.1 | Bipolar | Mental Disorders | 1.03 | 0.971 – 1.1 | 0.295 | 1058 | 10580 | all | phecode |
| 296.2 | Depression | Mental Disorders | 1.02 | 1 – 1.04 | 0.0399 | 11805 | 118049 | all | phecode |
| 296.22 | Major depressive disorder | Mental Disorders | 1.04 | 0.933 – 1.16 | 0.47 | 361 | 3610 | all | phecode |
| 297 | Suicidal ideation or attempt | Mental Disorders | 0.963 | 0.86 – 1.08 | 0.514 | 343 | 3391 | all | phecode |
| 297.2 | Suicide or self-inflicted injury | Mental Disorders | 0.949 | 0.843 – 1.07 | 0.377 | 319 | 3161 | all | phecode |
| 300 | Anxiety disorders | Mental Disorders | 1.02 | 0.995 – 1.05 | 0.123 | 6904 | 69029 | all | phecode |
| 300.1 | Anxiety disorder | Mental Disorders | 1.02 | 0.993 – 1.05 | 0.15 | 6341 | 63399 | all | phecode |
| 300.11 | Generalized anxiety disorder | Mental Disorders | 1.02 | 0.86 – 1.2 | 0.83 | 150 | 1500 | all | phecode |
| 300.12 | Agorophobia, social phobia, and panic disorder | Mental Disorders | 1.03 | 0.954 – 1.11 | 0.44 | 704 | 7040 | all | phecode |
| 300.13 | Phobia | Mental Disorders | 1.01 | 0.92 – 1.11 | 0.841 | 497 | 4970 | all | phecode |
| 300.3 | Obsessive-compulsive disorders | Mental Disorders | 1.1 | 0.926 – 1.31 | 0.264 | 140 | 1400 | all | phecode |
| 300.4 | Dysthymic disorder | Mental Disorders | 1.24 | 0.943 – 1.64 | 0.115 | 53 | 530 | all | phecode |
| 300.8 | Acute reaction to stress | Mental Disorders | 1.12 | 0.93 – 1.34 | 0.227 | 125 | 1250 | all | phecode |
| 300.9 | Posttraumatic stress disorder | Mental Disorders | 0.94 | 0.773 – 1.14 | 0.53 | 113 | 1130 | all | phecode |
| 301 | Personality disorders | Mental Disorders | 1.09 | 0.978 – 1.22 | 0.111 | 337 | 3366 | all | phecode |
| 301.2 | Antisocial/borderline personality disorder | Mental Disorders | 1.05 | 0.872 – 1.27 | 0.576 | 119 | 1186 | all | phecode |
| 302 | Sexual and gender identity disorders | Mental Disorders | 0.918 | 0.816 – 1.03 | 0.149 | 322 | 3220 | all | phecode |
| 303 | Psychogenic and somatoform disorders | Mental Disorders | 1.09 | 0.989 – 1.19 | 0.0829 | 489 | 4890 | all | phecode |
| 303.3 | Psychogenic disorder | Mental Disorders | 1.13 | 1.01 – 1.26 | 0.0286 | 354 | 3540 | all | phecode |
| 303.4 | Somatoform disorder | Mental Disorders | 0.968 | 0.802 – 1.16 | 0.726 | 124 | 1240 | all | phecode |
| 304 | Adjustment reaction | Mental Disorders | 1 | 0.885 – 1.13 | 0.996 | 295 | 2950 | all | phecode |
| 306 | Other mental disorder | Mental Disorders | 1.03 | 1.01 – 1.04 | 0.000101 | 28125 | 230574 | all | phecode |
| 306.9 | Tension headache | Mental Disorders | 0.996 | 0.886 – 1.12 | 0.946 | 315 | 3150 | all | phecode |
| 313 | Pervasive developmental disorders | Mental Disorders | 1 | 0.791 – 1.27 | 0.982 | 77 | 770 | all | phecode |
| 313.3 | Autism | Mental Disorders | 1.06 | 0.801 – 1.4 | 0.665 | 54 | 540 | all | phecode |
| 315 | Develomental delays and disorders | Mental Disorders | 0.971 | 0.869 – 1.08 | 0.601 | 353 | 3530 | all | phecode |
| 315.2 | Speech and language disorder | Mental Disorders | 1.08 | 0.866 – 1.34 | 0.493 | 89 | 890 | all | phecode |
| 316 | Substance addiction and disorders | Mental Disorders | 0.983 | 0.885 – 1.09 | 0.751 | 395 | 3950 | all | phecode |
| 316.1 | Polyneuropathy due to drugs | Mental Disorders | 1.06 | 0.812 – 1.38 | 0.65 | 60 | 600 | all | phecode |
| 317 | Alcohol-related disorders | Mental Disorders | 1.05 | 1.03 – 1.07 | 1.42e-06 | 12829 | 128124 | all | phecode |
| 317.1 | Alcoholism | Mental Disorders | 1.04 | 1.02 – 1.07 | 0.000129 | 8924 | 89210 | all | phecode |
| 317.11 | Alcoholic liver damage | Mental Disorders | 1.03 | 0.96 – 1.11 | 0.397 | 842 | 8420 | all | phecode |
| 318 | Tobacco use disorder | Mental Disorders | 1.03 | 1.01 – 1.04 | 0.000358 | 19447 | 185990 | all | phecode |
| 320 | Meningitis | Neurological | 0.979 | 0.887 – 1.08 | 0.671 | 448 | 4480 | all | phecode |
| 323 | Encephalitis | Neurological | 0.978 | 0.874 – 1.09 | 0.694 | 353 | 3530 | all | phecode |
| 323.2 | Acute (transverse) myelitis | Neurological | 0.782 | 0.604 – 1.01 | 0.0558 | 74 | 740 | all | phecode |
| 324 | Other CNS infection and poliomyelitis | Neurological | 0.97 | 0.858 – 1.09 | 0.621 | 295 | 2950 | all | phecode |
| 327 | Sleep disorders | Neurological | 1.04 | 0.975 – 1.1 | 0.259 | 1170 | 11700 | all | phecode |
| 327.3 | Sleep apnea | Neurological | 1.11 | 0.998 – 1.23 | 0.0539 | 404 | 4040 | all | phecode |
| 327.4 | Insomnia | Neurological | 0.982 | 0.834 – 1.15 | 0.825 | 165 | 1650 | all | phecode |
| 327.41 | Organic or persistent insomnia | Neurological | 0.909 | 0.759 – 1.09 | 0.291 | 138 | 1380 | all | phecode |
| 331 | Other cerebral degenerations | Neurological | 0.981 | 0.922 – 1.04 | 0.541 | 1146 | 11460 | all | phecode |
| 331.1 | Hydrocephalus | Neurological | 0.946 | 0.861 – 1.04 | 0.244 | 502 | 5020 | all | phecode |
| 331.9 | Cerebral degeneration, unspecified | Neurological | 0.999 | 0.903 – 1.1 | 0.983 | 429 | 4290 | all | phecode |
| 332 | Parkinson's disease | Neurological | 1.02 | 0.955 – 1.08 | 0.622 | 1128 | 11280 | all | phecode |
| 333 |
Extrapyramidal disease and abnormal movementExtrapyramidal disease and abnormal movement disorders
|
Neurological | 1.03 | 0.965 – 1.11 | 0.335 | 901 | 9010 | all | phecode |
| 333.1 | Essential tremor | Neurological | 1 | 0.868 – 1.15 | 0.997 | 216 | 2160 | all | phecode |
| 333.2 | Myoclonus | Neurological | 0.939 | 0.754 – 1.16 | 0.565 | 96 | 960 | all | phecode |
| 333.4 | Torsion dystonia | Neurological | 1.07 | 0.936 – 1.21 | 0.328 | 253 | 2530 | all | phecode |
| 334 | Degenerative disease of the spinal cord | Neurological | 1.02 | 0.967 – 1.07 | 0.528 | 1818 | 18180 | all | phecode |
| 334.1 | Spinocerebellar disease | Neurological | 0.964 | 0.794 – 1.17 | 0.703 | 117 | 1170 | all | phecode |
| 334.2 | Anterior horn cell disease | Neurological | 1.08 | 0.949 – 1.23 | 0.236 | 245 | 2450 | all | phecode |
| 335 | Multiple sclerosis | Neurological | 0.963 | 0.909 – 1.02 | 0.187 | 1354 | 13540 | all | phecode |
| 337 | Disorders of the autonomic nervous system | Neurological | 1.03 | 0.905 – 1.16 | 0.675 | 269 | 2690 | all | phecode |
| 337.1 | Peripheral autonomic neuropathy | Neurological | 0.943 | 0.735 – 1.2 | 0.632 | 72 | 720 | all | phecode |
| 338 | Pain | Neurological | 0.993 | 0.921 – 1.07 | 0.845 | 772 | 7720 | all | phecode |
| 338.1 | Acute pain | Neurological | 0.966 | 0.87 – 1.07 | 0.519 | 395 | 3950 | all | phecode |
| 338.2 | Chronic pain | Neurological | 1.01 | 0.91 – 1.12 | 0.822 | 383 | 3830 | all | phecode |
| 339 | Other headache syndromes | Neurological | 1.01 | 0.982 – 1.03 | 0.637 | 7843 | 78413 | all | phecode |
| 340 | Migraine | Neurological | 1 | 0.964 – 1.04 | 0.933 | 2867 | 28670 | all | phecode |
| 340.1 | Migrain with aura | Neurological | 0.999 | 0.865 – 1.15 | 0.987 | 212 | 2120 | all | phecode |
| 341 |
Other demyelinating diseases of central nervousOther demyelinating diseases of central nervous system
|
Neurological | 1.05 | 0.925 – 1.2 | 0.433 | 254 | 2540 | all | phecode |
| 342 | Hemiplegia | Neurological | 1.02 | 0.969 – 1.08 | 0.408 | 1498 | 14980 | all | phecode |
| 343 | Infantile cerebral palsy | Neurological | 1.01 | 0.849 – 1.2 | 0.916 | 145 | 1450 | all | phecode |
| 344 | Other paralytic syndromes | Neurological | 1.02 | 0.942 – 1.11 | 0.603 | 661 | 6610 | all | phecode |
| 345 | Epilepsy, recurrent seizures, convulsions | Neurological | 1.02 | 0.992 – 1.05 | 0.156 | 5083 | 50830 | all | phecode |
| 345.1 | Epilepsy | Neurological | 1.02 | 0.953 – 1.09 | 0.552 | 898 | 8980 | all | phecode |
| 345.11 | Generalized convulsive epilepsy | Neurological | 1.04 | 0.944 – 1.15 | 0.418 | 445 | 4450 | all | phecode |
| 345.12 | Partial epilepsy | Neurological | 0.999 | 0.882 – 1.13 | 0.982 | 279 | 2790 | all | phecode |
| 345.3 | Convulsions | Neurological | 1.06 | 1.01 – 1.11 | 0.0111 | 2235 | 22350 | all | phecode |
| 348 | Other conditions of brain | Neurological | 1.03 | 0.958 – 1.11 | 0.404 | 791 | 7910 | all | phecode |
| 348.2 | Cerebral edema and compression of brain | Neurological | 1.04 | 0.915 – 1.18 | 0.547 | 268 | 2680 | all | phecode |
| 348.4 | Cerebral cysts | Neurological | 0.938 | 0.784 – 1.12 | 0.481 | 136 | 1360 | all | phecode |
| 348.8 | Encephalopathy, not elsewhere classified | Neurological | 1.11 | 0.976 – 1.27 | 0.109 | 252 | 2520 | all | phecode |
| 349 |
Other and unspecified disorders of the nervousOther and unspecified disorders of the nervous system
|
Neurological | 0.988 | 0.883 – 1.11 | 0.839 | 342 | 3420 | all | phecode |
| 350 | Abnormal movement | Neurological | 1.04 | 0.998 – 1.08 | 0.0612 | 2691 | 26910 | all | phecode |
| 350.1 | Abnormal involuntary movements | Neurological | 1.04 | 0.967 – 1.11 | 0.306 | 888 | 8880 | all | phecode |
| 350.2 | Abnormality of gait | Neurological | 1.03 | 0.981 – 1.09 | 0.209 | 1599 | 15990 | all | phecode |
| 350.3 | Lack of coordination | Neurological | 1.15 | 1.03 – 1.28 | 0.00965 | 364 | 3640 | all | phecode |
| 351 | Other peripheral nerve disorders | Neurological | 1.01 | 0.993 – 1.03 | 0.22 | 12454 | 124540 | all | phecode |
| 352 | Disorders of other cranial nerves | Neurological | 0.999 | 0.944 – 1.06 | 0.963 | 1391 | 13910 | all | phecode |
| 352.1 | Trigeminal nerve disorders [CN5] | Neurological | 0.944 | 0.856 – 1.04 | 0.245 | 463 | 4630 | all | phecode |
| 352.2 | Facial nerve disorders [CN7] | Neurological | 1.03 | 0.962 – 1.11 | 0.378 | 880 | 8800 | all | phecode |
| 353 | Nerve root and plexus disorders | Neurological | 1.04 | 0.975 – 1.1 | 0.245 | 1137 | 11370 | all | phecode |
| 353.1 | Nerve plexus lesions | Neurological | 0.95 | 0.78 – 1.15 | 0.605 | 114 | 1140 | all | phecode |
| 353.2 | Nerve root lesions | Neurological | 1.18 | 0.898 – 1.55 | 0.225 | 57 | 570 | all | phecode |
| 356 | Hereditary and idiopathic peripheral neuropathy | Neurological | 1.02 | 0.864 – 1.21 | 0.798 | 152 | 1520 | all | phecode |
| 357 | Inflammatory and toxic neuropathy | Neurological | 0.915 | 0.865 – 0.968 | 0.00217 | 1367 | 13670 | all | phecode |
| 358 | Myoneural disorders | Neurological | 1.16 | 1.01 – 1.33 | 0.0393 | 213 | 2130 | all | phecode |
| 358.1 | Myasthenia gravis | Neurological | 1.19 | 1.03 – 1.37 | 0.0193 | 192 | 1920 | all | phecode |
| 359 | Muscular dystrophies and other myopathies | Neurological | 1.07 | 0.972 – 1.18 | 0.165 | 469 | 4690 | all | phecode |
| 359.1 | Muscular dystrophies | Neurological | 1.08 | 0.894 – 1.29 | 0.427 | 122 | 1220 | all | phecode |
| 359.2 | Myopathy | Neurological | 1.06 | 0.946 – 1.18 | 0.33 | 361 | 3610 | all | phecode |
| 360 | Disorders of the globe | Sense Organs | 1.06 | 0.95 – 1.19 | 0.281 | 337 | 3370 | all | phecode |
| 360.2 | Progressive myopia | Sense Organs | 1.1 | 0.968 – 1.25 | 0.137 | 251 | 2510 | all | phecode |
| 361 | Retinal detachments and defects | Sense Organs | 1.01 | 0.971 – 1.04 | 0.693 | 3256 | 32560 | all | phecode |
| 361.1 | Retinal detachment with retinal defect | Sense Organs | 1.02 | 0.962 – 1.08 | 0.546 | 1389 | 13890 | all | phecode |
| 361.2 | Retinoschisis and retinal cysts | Sense Organs | 0.799 | 0.615 – 1.03 | 0.0832 | 68 | 680 | all | phecode |
| 362 | Other retinal disorders | Sense Organs | 0.983 | 0.951 – 1.02 | 0.328 | 3858 | 38580 | all | phecode |
| 362.2 |
Degeneration of macula and posterior pole ofDegeneration of macula and posterior pole of retina
|
Sense Organs | 0.983 | 0.94 – 1.03 | 0.453 | 2184 | 21840 | all | phecode |
| 362.29 | Macular degeneration (senile) of retina NOS | Sense Organs | 0.985 | 0.942 – 1.03 | 0.511 | 2181 | 21810 | all | phecode |
| 362.3 | Other nondiabetic retinopathy | Sense Organs | 0.941 | 0.796 – 1.11 | 0.464 | 160 | 1600 | all | phecode |
| 362.31 | Separation of retinal layers | Sense Organs | 0.899 | 0.727 – 1.11 | 0.316 | 99 | 990 | all | phecode |
| 362.4 | Retinal vascular changes and abnomalities | Sense Organs | 0.962 | 0.895 – 1.03 | 0.286 | 847 | 8470 | all | phecode |
| 362.6 | Peripheral retinal degenerations | Sense Organs | 1.01 | 0.866 – 1.18 | 0.9 | 183 | 1830 | all | phecode |
| 362.7 | Hereditary retinal dystrophies | Sense Organs | 0.927 | 0.733 – 1.16 | 0.514 | 82 | 820 | all | phecode |
| 362.8 | Retinal hemorrhage/ischemia | Sense Organs | 0.998 | 0.821 – 1.21 | 0.984 | 116 | 1160 | all | phecode |
| 363 |
Chorioretinal inflammations, scars, and otherChorioretinal inflammations, scars, and other disorders of choroid
|
Sense Organs | 1.02 | 0.874 – 1.2 | 0.766 | 171 | 1710 | all | phecode |
| 363.3 | Chorioretinal scars | Sense Organs | 1.03 | 0.805 – 1.32 | 0.789 | 69 | 690 | all | phecode |
| 364 | Corneal opacity and other disorders of cornea | Sense Organs | 0.963 | 0.888 – 1.04 | 0.363 | 658 | 6580 | all | phecode |
| 364.2 | Corneal edema | Sense Organs | 0.874 | 0.689 – 1.1 | 0.258 | 80 | 800 | all | phecode |
| 364.4 | Corneal degenerations | Sense Organs | 1.03 | 0.894 – 1.19 | 0.663 | 208 | 2080 | all | phecode |
| 364.41 | Keratoconus | Sense Organs | 1.04 | 0.835 – 1.3 | 0.711 | 87 | 870 | all | phecode |
| 364.5 | Corneal dystrophy | Sense Organs | 1.05 | 0.91 – 1.21 | 0.5 | 211 | 2110 | all | phecode |
| 364.9 | Cornea replaced by transplant | Sense Organs | 1.1 | 0.893 – 1.35 | 0.363 | 100 | 1000 | all | phecode |
| 365 | Glaucoma | Sense Organs | 1.03 | 0.997 – 1.06 | 0.0744 | 4430 | 44300 | all | phecode |
| 365.1 | Open-angle glaucoma | Sense Organs | 1.07 | 1.01 – 1.14 | 0.0333 | 1029 | 10290 | all | phecode |
| 365.11 | Primary open angle glaucoma | Sense Organs | 1.08 | 1.01 – 1.15 | 0.026 | 1023 | 10230 | all | phecode |
| 365.2 | Primary angle-closure glaucoma | Sense Organs | 0.986 | 0.911 – 1.07 | 0.731 | 700 | 7000 | all | phecode |
| 366 | Cataract | Sense Organs | 1.01 | 0.995 – 1.03 | 0.174 | 19997 | 169205 | all | phecode |
| 366.1 | Nonsenile Cataract | Sense Organs | 1.05 | 0.817 – 1.33 | 0.708 | 70 | 700 | all | phecode |
| 366.2 | Senile cataract | Sense Organs | 1.01 | 0.99 – 1.04 | 0.258 | 8261 | 82116 | all | phecode |
| 366.3 | Traumatic cataract | Sense Organs | 1.04 | 0.843 – 1.27 | 0.736 | 102 | 1020 | all | phecode |
| 367 |
Disorders of refraction and accommodationDisorders of refraction and accommodation; blindness and low vision
|
Sense Organs | 1.01 | 0.973 – 1.06 | 0.494 | 2428 | 24280 | all | phecode |
| 367.1 | Myopia | Sense Organs | 1.01 | 0.95 – 1.07 | 0.797 | 1255 | 12550 | all | phecode |
| 367.2 | Astigmatism | Sense Organs | 1.12 | 0.967 – 1.3 | 0.125 | 190 | 1900 | all | phecode |
| 367.8 | Hypermetropia | Sense Organs | 1.06 | 0.927 – 1.2 | 0.407 | 252 | 2520 | all | phecode |
| 367.9 | Blindness and low vision | Sense Organs | 1.01 | 0.931 – 1.09 | 0.888 | 723 | 7230 | all | phecode |
| 368 | Visual disturbances | Sense Organs | 1.02 | 0.978 – 1.06 | 0.413 | 2990 | 29900 | all | phecode |
| 368.1 | Amblyopia | Sense Organs | 1.1 | 1 – 1.2 | 0.0381 | 535 | 5350 | all | phecode |
| 368.2 | Diplopia and disorders of binocular vision | Sense Organs | 0.996 | 0.922 – 1.08 | 0.918 | 730 | 7300 | all | phecode |
| 368.3 | Anisometropia | Sense Organs | 0.963 | 0.813 – 1.14 | 0.652 | 155 | 1550 | all | phecode |
| 368.9 | Subjective visual disturbances | Sense Organs | 1.02 | 0.942 – 1.11 | 0.566 | 614 | 6140 | all | phecode |
| 369 | Infection of the eye | Sense Organs | 1.02 | 0.939 – 1.12 | 0.583 | 560 | 5600 | all | phecode |
| 369.2 | Eye infection, viral | Sense Organs | 1 | 0.832 – 1.2 | 0.979 | 126 | 1260 | all | phecode |
| 369.5 | Conjunctivitis, infectious | Sense Organs | 1.15 | 0.999 – 1.32 | 0.0488 | 213 | 2130 | all | phecode |
| 370 | Keratitis | Sense Organs | 0.995 | 0.881 – 1.12 | 0.93 | 297 | 2970 | all | phecode |
| 370.1 | Corneal ulcer | Sense Organs | 1.04 | 0.87 – 1.23 | 0.681 | 141 | 1410 | all | phecode |
| 371 | Inflammation of the eye | Sense Organs | 0.974 | 0.939 – 1.01 | 0.162 | 3168 | 31680 | all | phecode |
| 371.1 | Uveitis, noninfectious or NOS | Sense Organs | 0.955 | 0.868 – 1.05 | 0.334 | 486 | 4860 | all | phecode |
| 371.3 | Inflammation of eyelids | Sense Organs | 0.988 | 0.947 – 1.03 | 0.579 | 2391 | 23910 | all | phecode |
| 372 | Disorders of conjunctiva | Sense Organs | 0.927 | 0.859 – 1 | 0.049 | 764 | 7640 | all | phecode |
| 374 | Other disorders of eyelids | Sense Organs | 1.05 | 1.03 – 1.08 | 0.000128 | 5700 | 57000 | all | phecode |
| 374.1 | Ectropion or entropion | Sense Organs | 1.1 | 1.04 – 1.17 | 0.00224 | 1066 | 10660 | all | phecode |
| 374.3 | Ptosis of eyelid | Sense Organs | 1.03 | 0.985 – 1.08 | 0.181 | 1826 | 18260 | all | phecode |
| 375 | Disorders of lacrimal system | Sense Organs | 1.06 | 1.01 – 1.1 | 0.0141 | 2213 | 22130 | all | phecode |
| 375.2 | Epiphora | Sense Organs | 1.11 | 1.03 – 1.18 | 0.00381 | 899 | 8990 | all | phecode |
| 376 | Disorders of the orbit | Sense Organs | 1.09 | 0.871 – 1.36 | 0.443 | 86 | 860 | all | phecode |
| 377 | Disorders of optic nerve and visual pathways | Sense Organs | 1.02 | 0.911 – 1.13 | 0.78 | 370 | 3700 | all | phecode |
| 377.1 | Optic atrophy | Sense Organs | 0.767 | 0.575 – 1.01 | 0.0608 | 58 | 580 | all | phecode |
| 377.3 | Optic neuritis/neuropathy | Sense Organs | 0.933 | 0.772 – 1.12 | 0.463 | 125 | 1250 | all | phecode |
| 378 |
Strabismus and other disorders of binocular eyeStrabismus and other disorders of binocular eye movements
|
Sense Organs | 1.03 | 0.974 – 1.09 | 0.305 | 1437 | 14370 | all | phecode |
| 378.1 | Strabismus (not specified as paralytic) | Sense Organs | 1.02 | 0.953 – 1.09 | 0.548 | 915 | 9150 | all | phecode |
| 378.2 | Nystagmus and other irregular eye movements | Sense Organs | 0.985 | 0.854 – 1.14 | 0.838 | 214 | 2140 | all | phecode |
| 378.5 | Paralytic strabismus | Sense Organs | 1.05 | 0.923 – 1.18 | 0.482 | 276 | 2760 | all | phecode |
| 379 | Other disorders of eye | Sense Organs | 0.995 | 0.962 – 1.03 | 0.791 | 3740 | 37400 | all | phecode |
| 379.2 | Disorders of vitreous body | Sense Organs | 1 | 0.95 – 1.06 | 0.877 | 1368 | 13680 | all | phecode |
| 379.3 | Aphakia and other disorders of lens | Sense Organs | 1.02 | 0.971 – 1.07 | 0.445 | 1810 | 18100 | all | phecode |
| 379.4 | Anomalies of pupillary function | Sense Organs | 0.851 | 0.659 – 1.09 | 0.202 | 70 | 700 | all | phecode |
| 379.5 | Disorders of iris and ciliary body | Sense Organs | 0.907 | 0.816 – 1.01 | 0.0662 | 401 | 4010 | all | phecode |
| 380 | Disorders of external ear | Sense Organs | 1 | 0.921 – 1.09 | 0.997 | 643 | 6430 | all | phecode |
| 381 | Otitis media and Eustachian tube disorders | Sense Organs | 1.02 | 0.977 – 1.07 | 0.356 | 2253 | 22530 | all | phecode |
| 381.1 | Otitis media | Sense Organs | 1.02 | 0.968 – 1.07 | 0.513 | 1820 | 18200 | all | phecode |
| 381.11 | Suppurative and unspecified otitis media | Sense Organs | 1.03 | 0.958 – 1.1 | 0.438 | 854 | 8540 | all | phecode |
| 381.2 | Eustachian tube disorders | Sense Organs | 0.942 | 0.809 – 1.1 | 0.438 | 191 | 1910 | all | phecode |
| 381.3 | Mastoiditis & related conditions | Sense Organs | 0.988 | 0.841 – 1.16 | 0.885 | 171 | 1710 | all | phecode |
| 381.9 | Otorrhea | Sense Organs | 0.989 | 0.873 – 1.12 | 0.856 | 280 | 2800 | all | phecode |
| 382 | Otalgia | Sense Organs | 0.981 | 0.871 – 1.1 | 0.756 | 309 | 3090 | all | phecode |
| 383 | Otosclerosis | Sense Organs | 1.19 | 1.06 – 1.33 | 0.00353 | 309 | 3090 | all | phecode |
| 384 | Other disorders of tympanic membrane | Sense Organs | 1 | 0.948 – 1.06 | 0.929 | 1362 | 13620 | all | phecode |
| 384.4 | Perforation of tympanic membrane | Sense Organs | 0.997 | 0.935 – 1.06 | 0.938 | 1043 | 10430 | all | phecode |
| 385 | Other disorders of middle ear and mastoid | Sense Organs | 1.03 | 0.962 – 1.11 | 0.369 | 827 | 8270 | all | phecode |
| 385.3 | Cholesteatoma | Sense Organs | 1.07 | 0.983 – 1.16 | 0.115 | 607 | 6070 | all | phecode |
| 385.5 |
Tympanosclerosis and middle ear disease relatedTympanosclerosis and middle ear disease related to otitis media
|
Sense Organs | 1.03 | 0.899 – 1.17 | 0.688 | 241 | 2410 | all | phecode |
| 386 |
Vertiginous syndromes and other disorders ofVertiginous syndromes and other disorders of vestibular system
|
Sense Organs | 1.04 | 0.993 – 1.1 | 0.0887 | 1765 | 17650 | all | phecode |
| 386.1 | Meniere's disease | Sense Organs | 1.09 | 1 – 1.19 | 0.0383 | 578 | 5780 | all | phecode |
| 386.2 | Peripheral or central vertigo | Sense Organs | 1.04 | 0.931 – 1.15 | 0.52 | 379 | 3790 | all | phecode |
| 386.3 | Labyrinthitis | Sense Organs | 1.01 | 0.941 – 1.09 | 0.702 | 767 | 7670 | all | phecode |
| 386.9 |
Dizziness and giddiness (Light-headedness andDizziness and giddiness (Light-headedness and vertigo)
|
Sense Organs | 1.04 | 0.907 – 1.18 | 0.597 | 243 | 2430 | all | phecode |
| 388 | Other disorders of ear | Sense Organs | 1.1 | 0.949 – 1.27 | 0.203 | 202 | 2020 | all | phecode |
| 389 | Hearing loss | Sense Organs | 1.04 | 1.01 – 1.07 | 0.0192 | 4243 | 42430 | all | phecode |
| 389.1 | Sensorineural hearing loss | Sense Organs | 0.974 | 0.883 – 1.07 | 0.592 | 456 | 4560 | all | phecode |
| 389.2 | Conductive hearing loss | Sense Organs | 1.1 | 0.994 – 1.21 | 0.0632 | 450 | 4500 | all | phecode |
| 389.4 | Tinnitus | Sense Organs | 0.96 | 0.875 – 1.05 | 0.378 | 512 | 5120 | all | phecode |
| 394 | Rheumatic disease of the heart valves | Circulatory System | 1.01 | 0.985 – 1.04 | 0.348 | 4912 | 49120 | all | phecode |
| 394.2 | Mitral valve disease | Circulatory System | 1.01 | 0.969 – 1.04 | 0.758 | 2992 | 29920 | all | phecode |
| 394.3 | Aortic valve disease | Circulatory System | 1.04 | 0.981 – 1.1 | 0.185 | 1283 | 12830 | all | phecode |
| 394.7 | Disease of tricuspid valve | Circulatory System | 1.02 | 0.96 – 1.09 | 0.479 | 1054 | 10540 | all | phecode |
| 395 | Heart valve disorders | Circulatory System | 1.01 | 0.974 – 1.04 | 0.73 | 4249 | 42490 | all | phecode |
| 395.1 | Nonrheumatic mitral valve disorders | Circulatory System | 1 | 0.965 – 1.04 | 0.88 | 2892 | 28920 | all | phecode |
| 395.2 | Nonrheumatic aortic valve disorders | Circulatory System | 0.992 | 0.875 – 1.12 | 0.903 | 278 | 2780 | all | phecode |
| 395.3 | Nonrheumatic tricuspid valve disorders | Circulatory System | 1.25 | 1.02 – 1.52 | 0.0311 | 104 | 1040 | all | phecode |
| 395.4 | Nonrheumatic pulmonary valve disorders | Circulatory System | 0.885 | 0.713 – 1.09 | 0.257 | 96 | 960 | all | phecode |
| 395.6 | Heart valve replaced | Circulatory System | 1.02 | 0.968 – 1.08 | 0.44 | 1494 | 14940 | all | phecode |
| 396 | Abnormal heart sounds | Circulatory System | 0.98 | 0.919 – 1.04 | 0.526 | 1049 | 10490 | all | phecode |
| 401 | Hypertension | Circulatory System | 1.01 | 1 – 1.02 | 0.0119 | 74203 | 267481 | all | phecode |
| 401.1 | Essential hypertension | Circulatory System | 1.01 | 1 – 1.02 | 0.0137 | 73892 | 266307 | all | phecode |
| 401.2 | Hypertensive heart and/or renal disease | Circulatory System | 1.03 | 0.979 – 1.08 | 0.287 | 1910 | 19099 | all | phecode |
| 401.21 | Hypertensive heart disease | Circulatory System | 0.997 | 0.895 – 1.11 | 0.959 | 370 | 3700 | all | phecode |
| 401.22 | Hypertensive chronic kidney disease | Circulatory System | 1.04 | 0.985 – 1.09 | 0.166 | 1551 | 15510 | all | phecode |
| 401.3 | Other hypertensive complications | Circulatory System | 0.969 | 0.815 – 1.15 | 0.72 | 144 | 1440 | all | phecode |
| 402 |
Elevated blood pressure reading withoutElevated blood pressure reading without diagnosis of hypertension
|
Circulatory System | 1.03 | 0.971 – 1.08 | 0.366 | 1481 | 14810 | all | phecode |
| 411 | Ischemic Heart Disease | Circulatory System | 1.01 | 0.996 – 1.02 | 0.194 | 31407 | 211307 | all | phecode |
| 411.1 | Unstable angina (intermediate coronary syndrome) | Circulatory System | 1.03 | 1 – 1.06 | 0.0502 | 5161 | 51604 | all | phecode |
| 411.2 | Myocardial infarction | Circulatory System | 1.01 | 0.99 – 1.03 | 0.342 | 11981 | 112940 | all | phecode |
| 411.3 | Angina pectoris | Circulatory System | 1.02 | 1.01 – 1.04 | 0.00608 | 15926 | 144026 | all | phecode |
| 411.4 | Coronary atherosclerosis | Circulatory System | 1.01 | 0.992 – 1.02 | 0.376 | 20207 | 154941 | all | phecode |
| 411.41 | Aneurysm and dissection of heart | Circulatory System | 0.97 | 0.896 – 1.05 | 0.444 | 701 | 7010 | all | phecode |
| 411.8 |
Other chronic ischemic heart diseaseOther chronic ischemic heart disease, unspecified
|
Circulatory System | 1.01 | 0.996 – 1.03 | 0.135 | 15331 | 132062 | all | phecode |
| 411.9 |
Other acute and subacute forms of ischemicOther acute and subacute forms of ischemic heart disease
|
Circulatory System | 1.04 | 0.977 – 1.1 | 0.234 | 1218 | 12180 | all | phecode |
| 414 | Other forms of chronic heart disease | Circulatory System | 0.993 | 0.946 – 1.04 | 0.78 | 1827 | 18270 | all | phecode |
| 414.2 | ASCVD | Circulatory System | 0.887 | 0.689 – 1.13 | 0.339 | 72 | 720 | all | phecode |
| 415 | Pulmonary heart disease | Circulatory System | 1.01 | 0.975 – 1.04 | 0.718 | 4531 | 45310 | all | phecode |
| 415.1 | Acute pulmonary heart disease | Circulatory System | 0.995 | 0.782 – 1.26 | 0.969 | 75 | 750 | all | phecode |
| 415.11 | Pulmonary embolism and infarction, acute | Circulatory System | 0.995 | 0.782 – 1.26 | 0.969 | 75 | 750 | all | phecode |
| 415.2 | Chronic pulmonary heart disease | Circulatory System | 0.99 | 0.91 – 1.08 | 0.819 | 602 | 6020 | all | phecode |
| 415.21 | Primary pulmonary hypertension | Circulatory System | 0.981 | 0.889 – 1.08 | 0.704 | 447 | 4470 | all | phecode |
| 416 | Cardiomegaly | Circulatory System | 1.03 | 0.988 – 1.07 | 0.171 | 2686 | 26860 | all | phecode |
| 418 | Nonspecific chest pain | Circulatory System | 1.01 | 0.994 – 1.02 | 0.308 | 28677 | 270690 | all | phecode |
| 418.1 | Precordial pain | Circulatory System | 1.02 | 0.99 – 1.06 | 0.163 | 3567 | 35670 | all | phecode |
| 420 | Carditis | Circulatory System | 1.06 | 1.01 – 1.11 | 0.0117 | 2146 | 21460 | all | phecode |
| 420.1 | Myocarditis | Circulatory System | 0.907 | 0.753 – 1.09 | 0.297 | 127 | 1270 | all | phecode |
| 420.2 | Pericarditis | Circulatory System | 1.05 | 0.997 – 1.12 | 0.0637 | 1346 | 13460 | all | phecode |
| 420.21 | Acute pericarditis | Circulatory System | 1.13 | 0.982 – 1.29 | 0.0855 | 224 | 2240 | all | phecode |
| 420.22 | Chronic pericarditis | Circulatory System | 0.993 | 0.815 – 1.21 | 0.942 | 113 | 1130 | all | phecode |
| 420.3 | Endocarditis | Circulatory System | 1.08 | 1 – 1.17 | 0.0403 | 719 | 7190 | all | phecode |
| 425 | Cardiomyopathy | Circulatory System | 1.02 | 0.967 – 1.09 | 0.411 | 1277 | 12770 | all | phecode |
| 425.1 | Primary/intrinsic cardiomyopathies | Circulatory System | 1.02 | 0.961 – 1.08 | 0.512 | 1238 | 12380 | all | phecode |
| 425.11 | Hypertrophic obstructive cardiomyopathy | Circulatory System | 0.971 | 0.81 – 1.16 | 0.751 | 132 | 1320 | all | phecode |
| 425.12 | Other hypertrophic cardiomyopathy | Circulatory System | 0.96 | 0.815 – 1.13 | 0.624 | 164 | 1640 | all | phecode |
| 425.8 | Other cardiomyopathy | Circulatory System | 1 | 0.765 – 1.3 | 0.994 | 60 | 600 | all | phecode |
| 426 | Cardiac conduction disorders | Circulatory System | 1.03 | 1 – 1.05 | 0.025 | 6937 | 69370 | all | phecode |
| 426.2 | Atrioventricular [AV] block | Circulatory System | 1.03 | 0.987 – 1.08 | 0.17 | 2126 | 21259 | all | phecode |
| 426.21 | First degree AV block | Circulatory System | 1.05 | 0.986 – 1.12 | 0.123 | 989 | 9890 | all | phecode |
| 426.23 | Second degree AV block | Circulatory System | 0.997 | 0.904 – 1.1 | 0.951 | 453 | 4530 | all | phecode |
| 426.24 | Atrioventricular block, complete | Circulatory System | 1.01 | 0.925 – 1.1 | 0.854 | 588 | 5871 | all | phecode |
| 426.25 | Other heart block | Circulatory System | 0.963 | 0.802 – 1.15 | 0.684 | 132 | 1320 | all | phecode |
| 426.3 | Bundle branch block | Circulatory System | 1.03 | 0.997 – 1.07 | 0.0723 | 3344 | 33440 | all | phecode |
| 426.31 | Right bundle branch block | Circulatory System | 1.06 | 1 – 1.11 | 0.0487 | 1496 | 14960 | all | phecode |
| 426.32 | Left bundle branch block | Circulatory System | 1.02 | 0.971 – 1.07 | 0.435 | 1753 | 17530 | all | phecode |
| 426.4 | Anomalous atrioventricular excitation | Circulatory System | 0.931 | 0.811 – 1.07 | 0.305 | 233 | 2330 | all | phecode |
| 426.8 | Other cardiac conduction disorders | Circulatory System | 0.984 | 0.749 – 1.28 | 0.903 | 60 | 600 | all | phecode |
| 426.9 | Cardiac pacemaker/device in situ | Circulatory System | 1.03 | 0.989 – 1.07 | 0.15 | 2485 | 24848 | all | phecode |
| 426.91 | Cardiac pacemaker in situ | Circulatory System | 1.03 | 0.987 – 1.08 | 0.168 | 2281 | 22806 | all | phecode |
| 427 | Cardiac dysrhythmias | Circulatory System | 1.02 | 1 – 1.03 | 0.018 | 24341 | 206836 | all | phecode |
| 427.1 | Paroxysmal tachycardia, unspecified | Circulatory System | 1.01 | 0.975 – 1.05 | 0.535 | 3219 | 32190 | all | phecode |
| 427.11 | Paroxysmal supraventricular tachycardia | Circulatory System | 1.02 | 0.973 – 1.06 | 0.479 | 2353 | 23530 | all | phecode |
| 427.12 | Paroxysmal ventricular tachycardia | Circulatory System | 1.03 | 0.96 – 1.1 | 0.427 | 938 | 9380 | all | phecode |
| 427.2 | Atrial fibrillation and flutter | Circulatory System | 1.02 | 1 – 1.04 | 0.0176 | 14669 | 133702 | all | phecode |
| 427.3 | Other specified cardiac dysrhythmias | Circulatory System | 1.01 | 0.976 – 1.05 | 0.525 | 3234 | 32340 | all | phecode |
| 427.4 | Cardiac arrest and ventricular fibrillation | Circulatory System | 1.04 | 0.983 – 1.11 | 0.162 | 1200 | 12000 | all | phecode |
| 427.41 | Ventricular fibrillation and flutter | Circulatory System | 0.99 | 0.885 – 1.11 | 0.862 | 344 | 3440 | all | phecode |
| 427.42 | Cardiac arrest | Circulatory System | 1.04 | 0.977 – 1.11 | 0.203 | 991 | 9910 | all | phecode |
| 427.5 | Arrhythmia (cardiac) NOS | Circulatory System | 0.966 | 0.903 – 1.03 | 0.312 | 957 | 9570 | all | phecode |
| 427.6 | Premature beats | Circulatory System | 1.04 | 0.952 – 1.14 | 0.37 | 536 | 5360 | all | phecode |
| 427.61 | Supraventricular premature beats | Circulatory System | 1.05 | 0.865 – 1.26 | 0.633 | 117 | 1169 | all | phecode |
| 427.7 | Tachycardia NOS | Circulatory System | 1.01 | 0.965 – 1.05 | 0.7 | 2191 | 21899 | all | phecode |
| 427.8 | Sinoatrial node dysfunction (Bradycardia) | Circulatory System | 1.09 | 0.988 – 1.21 | 0.0825 | 403 | 4030 | all | phecode |
| 427.9 | Palpitations | Circulatory System | 1.04 | 1 – 1.07 | 0.0285 | 3816 | 38155 | all | phecode |
| 428 | Congestive heart failure; nonhypertensive | Circulatory System | 1.01 | 0.986 – 1.04 | 0.349 | 5621 | 56168 | all | phecode |
| 428.1 | Congestive heart failure (CHF) NOS | Circulatory System | 1.04 | 0.989 – 1.08 | 0.133 | 2106 | 21052 | all | phecode |
| 428.2 | Heart failure NOS | Circulatory System | 1 | 0.972 – 1.03 | 0.867 | 4457 | 44528 | all | phecode |
| 429 |
Ill-defined descriptions and complications ofIll-defined descriptions and complications of heart disease
|
Circulatory System | 1.05 | 0.973 – 1.13 | 0.209 | 734 | 7340 | all | phecode |
| 429.2 | Abnormal function study of cardiovascular system | Circulatory System | 1.04 | 0.95 – 1.14 | 0.39 | 524 | 5240 | all | phecode |
| 429.3 | Symptoms involving cardiovascular system | Circulatory System | 1.08 | 0.93 – 1.25 | 0.315 | 198 | 1980 | all | phecode |
| 430 | Intracranial hemorrhage | Circulatory System | 0.984 | 0.938 – 1.03 | 0.495 | 1908 | 19080 | all | phecode |
| 430.1 | Subarachnoid hemorrhage | Circulatory System | 0.98 | 0.913 – 1.05 | 0.583 | 855 | 8550 | all | phecode |
| 430.2 | Intracerebral hemorrhage | Circulatory System | 1 | 0.932 – 1.08 | 0.897 | 769 | 7690 | all | phecode |
| 430.3 | Subdural hemorrhage | Circulatory System | 0.866 | 0.759 – 0.986 | 0.0302 | 267 | 2670 | all | phecode |
| 433 | Cerebrovascular disease | Circulatory System | 1.02 | 0.998 – 1.04 | 0.0756 | 8804 | 87981 | all | phecode |
| 433.1 | Occlusion and stenosis of precerebral arteries | Circulatory System | 1.04 | 0.977 – 1.1 | 0.235 | 1187 | 11848 | all | phecode |
| 433.12 | Cerebral atherosclerosis | Circulatory System | 1.08 | 0.943 – 1.24 | 0.26 | 227 | 2270 | all | phecode |
| 433.2 | Occlusion of cerebral arteries | Circulatory System | 1.03 | 0.999 – 1.06 | 0.0577 | 4244 | 42423 | all | phecode |
| 433.21 |
Cerebral artery occlusion, with cerebralCerebral artery occlusion, with cerebral infarction
|
Circulatory System | 1.05 | 1 – 1.11 | 0.0509 | 1685 | 16840 | all | phecode |
| 433.3 | Cerebral ischemia | Circulatory System | 0.999 | 0.962 – 1.04 | 0.975 | 2920 | 29192 | all | phecode |
| 433.31 | Transient cerebral ischemia | Circulatory System | 0.999 | 0.955 – 1.05 | 0.971 | 2132 | 21312 | all | phecode |
| 433.5 | Cerebral aneurysm | Circulatory System | 0.995 | 0.895 – 1.1 | 0.919 | 391 | 3909 | all | phecode |
| 433.8 | Late effects of cerebrovascular disease | Circulatory System | 1.05 | 0.989 – 1.11 | 0.111 | 1270 | 12693 | all | phecode |
| 440 | Atherosclerosis | Circulatory System | 1.01 | 0.957 – 1.07 | 0.68 | 1390 | 13890 | all | phecode |
| 440.1 | Atherosclerosis of renal artery | Circulatory System | 0.955 | 0.783 – 1.16 | 0.645 | 113 | 1128 | all | phecode |
| 440.2 | Atherosclerosis of the extremities | Circulatory System | 1.02 | 0.95 – 1.1 | 0.556 | 811 | 8105 | all | phecode |
| 440.9 | Atherosclerosis of aorta | Circulatory System | 0.947 | 0.835 – 1.07 | 0.384 | 286 | 2860 | all | phecode |
| 441 | Vascular insufficiency of intestine | Circulatory System | 1.08 | 0.991 – 1.17 | 0.0801 | 620 | 6200 | all | phecode |
| 441.1 | Acute vascular insufficiency of intestine | Circulatory System | 1.03 | 0.907 – 1.16 | 0.674 | 283 | 2830 | all | phecode |
| 442 | Other aneurysm | Circulatory System | 1.03 | 0.982 – 1.08 | 0.227 | 1907 | 19057 | all | phecode |
| 442.1 | Aortic aneurysm | Circulatory System | 1.04 | 0.985 – 1.1 | 0.155 | 1468 | 14679 | all | phecode |
| 442.11 | Abdominal aortic aneurysm | Circulatory System | 1.03 | 0.961 – 1.1 | 0.411 | 939 | 9383 | all | phecode |
| 442.2 | Aneurysm of iliac artery | Circulatory System | 1.01 | 0.824 – 1.24 | 0.903 | 102 | 1020 | all | phecode |
| 442.3 | Aneurysm of artery of lower extremity | Circulatory System | 1.06 | 0.904 – 1.24 | 0.47 | 170 | 1700 | all | phecode |
| 442.4 | Arterial dissection | Circulatory System | 0.98 | 0.742 – 1.29 | 0.887 | 55 | 550 | all | phecode |
| 442.8 | Aneurysm of other specified artery | Circulatory System | 0.954 | 0.822 – 1.1 | 0.525 | 203 | 2030 | all | phecode |
| 443 | Peripheral vascular disease | Circulatory System | 1.01 | 0.977 – 1.04 | 0.573 | 3950 | 39492 | all | phecode |
| 443.1 | Raynaud's syndrome | Circulatory System | 1.03 | 0.965 – 1.09 | 0.42 | 1145 | 11450 | all | phecode |
| 443.7 |
Peripheral angiopathy in diseases classifiedPeripheral angiopathy in diseases classified elsewhere
|
Circulatory System | 0.947 | 0.851 – 1.05 | 0.31 | 390 | 3900 | all | phecode |
| 443.9 | Peripheral vascular disease, unspecified | Circulatory System | 1.01 | 0.97 – 1.05 | 0.622 | 2591 | 25902 | all | phecode |
| 444 | Arterial embolism and thrombosis | Circulatory System | 1.02 | 0.955 – 1.09 | 0.52 | 930 | 9300 | all | phecode |
| 444.1 |
Arterial embolism and thrombosis of lowerArterial embolism and thrombosis of lower extremity artery
|
Circulatory System | 0.981 | 0.898 – 1.07 | 0.674 | 556 | 5560 | all | phecode |
| 446 | Polyarteritis nodosa and allied conditions | Circulatory System | 0.985 | 0.916 – 1.06 | 0.69 | 829 | 8290 | all | phecode |
| 446.4 | Wegener's granulomatosis | Circulatory System | 0.893 | 0.765 – 1.04 | 0.149 | 187 | 1870 | all | phecode |
| 446.5 | Giant cell arteritis | Circulatory System | 1.06 | 0.95 – 1.17 | 0.31 | 386 | 3860 | all | phecode |
| 446.9 | Arteritis NOS | Circulatory System | 0.949 | 0.828 – 1.09 | 0.445 | 240 | 2400 | all | phecode |
| 447 | Other disorders of arteries and arterioles | Circulatory System | 1.02 | 0.967 – 1.08 | 0.43 | 1336 | 13360 | all | phecode |
| 447.1 | Stricture of artery | Circulatory System | 1.06 | 0.99 – 1.14 | 0.0936 | 873 | 8730 | all | phecode |
| 448 | Disease of capillaries | Circulatory System | 1.05 | 0.883 – 1.25 | 0.572 | 142 | 1420 | all | phecode |
| 450 | Noninfectious disorders of lymphatic channels | Circulatory System | 1.01 | 0.936 – 1.09 | 0.763 | 705 | 7050 | all | phecode |
| 451 | Phlebitis and thrombophlebitis | Circulatory System | 1.04 | 1.01 – 1.07 | 0.0205 | 4020 | 40200 | all | phecode |
| 451.2 |
Phlebitis and thrombophlebitis of lowerPhlebitis and thrombophlebitis of lower extremities
|
Circulatory System | 1.03 | 0.999 – 1.07 | 0.057 | 3707 | 37070 | all | phecode |
| 452 | Other venous embolism and thrombosis | Circulatory System | 0.975 | 0.893 – 1.06 | 0.575 | 566 | 5660 | all | phecode |
| 454 | Varicose veins | Circulatory System | 0.994 | 0.976 – 1.01 | 0.561 | 12019 | 120183 | all | phecode |
| 454.1 | Varicose veins of lower extremity | Circulatory System | 0.994 | 0.975 – 1.01 | 0.523 | 11549 | 115483 | all | phecode |
| 454.11 | Varicose veins of lower extremity, symptomtic | Circulatory System | 0.98 | 0.902 – 1.06 | 0.641 | 626 | 6257 | all | phecode |
| 455 | Hemorrhoids | Circulatory System | 1.02 | 1.01 – 1.03 | 0.00281 | 23500 | 234947 | all | phecode |
| 456 | Chronic venous insufficiency [CVI] | Circulatory System | 0.82 | 0.701 – 0.957 | 0.0119 | 188 | 1880 | all | phecode |
| 457 |
Encounter for long-term (current) use ofEncounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
|
Circulatory System | 1.02 | 0.828 – 1.26 | 0.835 | 97 | 966 | all | phecode |
| 458 | Hypotension | Circulatory System | 1 | 0.975 – 1.03 | 0.889 | 5801 | 58010 | all | phecode |
| 458.1 | Orthostatic hypotension | Circulatory System | 0.987 | 0.932 – 1.04 | 0.647 | 1339 | 13390 | all | phecode |
| 458.2 | Iatrogenic hypotension | Circulatory System | 1.09 | 0.951 – 1.24 | 0.212 | 234 | 2340 | all | phecode |
| 458.9 | Hypotension NOS | Circulatory System | 0.994 | 0.96 – 1.03 | 0.746 | 3502 | 35020 | all | phecode |
| 459 | Other disorders of circulatory system | Circulatory System | 1.02 | 1.01 – 1.04 | 0.00371 | 16386 | 161616 | all | phecode |
| 459.1 | Hemorrhage NOS | Circulatory System | 1.02 | 0.852 – 1.21 | 0.864 | 142 | 1420 | all | phecode |
| 459.9 | Circulatory disease NEC | Circulatory System | 1.02 | 1.01 – 1.04 | 0.00489 | 16173 | 159853 | all | phecode |
| 464 | Acute sinusitis | Respiratory | 1.03 | 0.887 – 1.19 | 0.712 | 196 | 1960 | all | phecode |
| 465 |
Acute upper respiratory infections of multipleAcute upper respiratory infections of multiple or unspecified sites
|
Respiratory | 1.01 | 0.968 – 1.05 | 0.639 | 2332 | 23320 | all | phecode |
| 465.2 | Acute pharyngitis | Respiratory | 0.957 | 0.892 – 1.03 | 0.227 | 868 | 8680 | all | phecode |
| 465.4 | Acute laryngitis and tracheitis | Respiratory | 1.05 | 0.892 – 1.23 | 0.561 | 166 | 1660 | all | phecode |
| 470 | Septal Deviations/Turbinate Hypertrophy | Respiratory | 1.02 | 0.989 – 1.05 | 0.207 | 4909 | 49081 | all | phecode |
| 471 | Nasal polyps | Respiratory | 1.03 | 0.993 – 1.07 | 0.119 | 3301 | 33009 | all | phecode |
| 472 | Chronic pharyngitis and nasopharyngitis | Respiratory | 1.09 | 1.02 – 1.16 | 0.0112 | 963 | 9630 | all | phecode |
| 473 | Diseases of the larynx and vocal cords | Respiratory | 1.04 | 1 – 1.09 | 0.0429 | 2623 | 26230 | all | phecode |
| 473.1 | Chronic laryngitis | Respiratory | 0.939 | 0.762 – 1.15 | 0.547 | 104 | 1040 | all | phecode |
| 473.3 | Paralysis/spasm of vocal cords or larynx | Respiratory | 0.994 | 0.875 – 1.13 | 0.93 | 265 | 2650 | all | phecode |
| 473.4 | Voice disturbance | Respiratory | 1.08 | 1.02 – 1.15 | 0.0117 | 1083 | 10830 | all | phecode |
| 474 | Acute and chronic tonsillitis | Respiratory | 0.997 | 0.951 – 1.04 | 0.888 | 2008 | 20072 | all | phecode |
| 474.1 | Acute tonsillitis | Respiratory | 1.02 | 0.935 – 1.1 | 0.701 | 613 | 6130 | all | phecode |
| 474.2 | Chronic tonsillitis and adenoiditis | Respiratory | 0.975 | 0.916 – 1.04 | 0.424 | 1124 | 11232 | all | phecode |
| 475 | Chronic sinusitis | Respiratory | 1.01 | 0.974 – 1.06 | 0.496 | 2596 | 25951 | all | phecode |
| 476 | Allergic rhinitis | Respiratory | 1.02 | 0.957 – 1.09 | 0.544 | 1059 | 10590 | all | phecode |
| 477 | Epistaxis or throat hemorrhage | Respiratory | 0.985 | 0.945 – 1.03 | 0.49 | 2452 | 24509 | all | phecode |
| 478 | Throat pain | Respiratory | 1.02 | 0.919 – 1.14 | 0.682 | 379 | 3790 | all | phecode |
| 479 | Other upper respiratory disease | Respiratory | 1.03 | 0.996 – 1.06 | 0.088 | 4089 | 40884 | all | phecode |
| 480 | Pneumonia | Respiratory | 1.01 | 0.993 – 1.03 | 0.206 | 10456 | 104475 | all | phecode |
| 480.1 | Bacterial pneumonia | Respiratory | 1.01 | 0.984 – 1.03 | 0.486 | 6691 | 66910 | all | phecode |
| 480.11 | Pneumococcal pneumonia | Respiratory | 1.01 | 0.983 – 1.04 | 0.493 | 5936 | 59360 | all | phecode |
| 480.12 | Pseudomonal pneumonia | Respiratory | 0.953 | 0.767 – 1.18 | 0.656 | 93 | 930 | all | phecode |
| 480.2 | Viral pneumonia | Respiratory | 1.17 | 0.921 – 1.47 | 0.189 | 73 | 730 | all | phecode |
| 480.3 | Pneumonia due to fungus (mycoses) | Respiratory | 0.917 | 0.742 – 1.13 | 0.41 | 101 | 1010 | all | phecode |
| 480.5 | Bronchopneumonia and lung abscess | Respiratory | 0.978 | 0.909 – 1.05 | 0.554 | 802 | 8020 | all | phecode |
| 481 | Influenza | Respiratory | 1 | 0.891 – 1.12 | 0.997 | 331 | 3310 | all | phecode |
| 483 | Acute bronchitis and bronchiolitis | Respiratory | 1.08 | 0.928 – 1.25 | 0.329 | 194 | 1940 | all | phecode |
| 495 | Asthma | Respiratory | 1.02 | 1 – 1.03 | 0.00852 | 25799 | 251156 | all | phecode |
| 495.2 | Asthma with exacerbation | Respiratory | 1.04 | 0.913 – 1.19 | 0.542 | 252 | 2520 | all | phecode |
| 496 | Chronic airway obstruction | Respiratory | 1.04 | 1.02 – 1.06 | 0.000433 | 10487 | 102024 | all | phecode |
| 496.1 | Emphysema | Respiratory | 1.04 | 0.986 – 1.09 | 0.16 | 1754 | 17540 | all | phecode |
| 496.2 | Chronic bronchitis | Respiratory | 1.03 | 0.992 – 1.07 | 0.12 | 2965 | 29592 | all | phecode |
| 496.21 | Obstructive chronic bronchitis | Respiratory | 1.03 | 0.987 – 1.07 | 0.191 | 2722 | 27164 | all | phecode |
| 496.3 | Bronchiectasis | Respiratory | 1.02 | 0.971 – 1.07 | 0.441 | 1893 | 18930 | all | phecode |
| 497 | Bronchitis | Respiratory | 0.942 | 0.867 – 1.02 | 0.159 | 634 | 6332 | all | phecode |
| 500 | Lung disease due to external agents | Respiratory | 1.02 | 0.918 – 1.13 | 0.74 | 413 | 4113 | all | phecode |
| 500.1 | Extrinsic allergic alveolitis | Respiratory | 1.14 | 0.905 – 1.44 | 0.25 | 79 | 790 | all | phecode |
| 500.2 | Pneumoconiosis | Respiratory | 0.998 | 0.873 – 1.14 | 0.97 | 244 | 2423 | all | phecode |
| 501 | Pneumonitis due to inhalation of food or vomitus | Respiratory | 1.1 | 1.02 – 1.19 | 0.0167 | 657 | 6570 | all | phecode |
| 502 | Postinflammatory pulmonary fibrosis | Respiratory | 0.963 | 0.899 – 1.03 | 0.276 | 924 | 9240 | all | phecode |
| 503 | Pulmonary congestion and hypostasis | Respiratory | 1 | 0.912 – 1.1 | 0.999 | 515 | 5150 | all | phecode |
| 504 | Other alveolar and parietoalveolar pneumonopathy | Respiratory | 1.03 | 0.924 – 1.16 | 0.551 | 330 | 3300 | all | phecode |
| 505 | Other pulmonary inflamation or edema | Respiratory | 0.925 | 0.707 – 1.21 | 0.561 | 61 | 610 | all | phecode |
| 506 | Empyema and pneumothorax | Respiratory | 0.991 | 0.933 – 1.05 | 0.775 | 1181 | 11803 | all | phecode |
| 507 | Pleurisy; pleural effusion | Respiratory | 1.01 | 0.98 – 1.03 | 0.661 | 6440 | 64382 | all | phecode |
| 508 |
Pulmonary collapse; interstitial andPulmonary collapse; interstitial and compensatory emphysema
|
Respiratory | 1.01 | 0.966 – 1.06 | 0.614 | 2002 | 20020 | all | phecode |
| 509 | Respiratory failure, insufficiency, arrest | Respiratory | 1.04 | 0.994 – 1.08 | 0.0914 | 2648 | 26474 | all | phecode |
| 509.1 | Respiratory failure | Respiratory | 1.05 | 1.01 – 1.1 | 0.0217 | 2079 | 20784 | all | phecode |
| 509.2 | Respiratory insufficiency | Respiratory | 1.04 | 0.989 – 1.09 | 0.126 | 1819 | 18184 | all | phecode |
| 509.5 | Respiratory arrest | Respiratory | 0.95 | 0.798 – 1.13 | 0.563 | 144 | 1440 | all | phecode |
| 509.8 |
Dependence on respirator [Ventilator] orDependence on respirator [Ventilator] or supplemental oxygen
|
Respiratory | 1.01 | 0.907 – 1.12 | 0.875 | 389 | 3890 | all | phecode |
| 510 | Other diseases of lung | Respiratory | 1.07 | 0.993 – 1.15 | 0.0739 | 757 | 7570 | all | phecode |
| 512 | Other symptoms of respiratory system | Respiratory | 1.03 | 1.01 – 1.05 | 0.00409 | 9079 | 90783 | all | phecode |
| 512.1 | Wheezing | Respiratory | 1 | 0.869 – 1.15 | 0.989 | 220 | 2200 | all | phecode |
| 512.2 | Painful respiration | Respiratory | 0.997 | 0.863 – 1.15 | 0.968 | 208 | 2080 | all | phecode |
| 512.7 | Shortness of breath | Respiratory | 1.03 | 1 – 1.06 | 0.0328 | 5855 | 58547 | all | phecode |
| 512.8 | Cough | Respiratory | 1.05 | 1.01 – 1.09 | 0.0166 | 2864 | 28636 | all | phecode |
| 512.9 | Other dyspnea | Respiratory | 1.05 | 0.984 – 1.13 | 0.133 | 907 | 9070 | all | phecode |
| 513 | Respiratory abnormalities | Respiratory | 1.04 | 0.957 – 1.13 | 0.346 | 614 | 6136 | all | phecode |
| 513.3 | Hypoventilation | Respiratory | 0.885 | 0.698 – 1.12 | 0.303 | 83 | 830 | all | phecode |
| 513.4 | Hyperventilation | Respiratory | 1.03 | 0.912 – 1.17 | 0.605 | 278 | 2780 | all | phecode |
| 513.8 | Disorders of diaphragm | Respiratory | 1.04 | 0.876 – 1.22 | 0.674 | 154 | 1540 | all | phecode |
| 514 | Abnormal findings examination of lungs | Respiratory | 1.04 | 0.996 – 1.08 | 0.0789 | 2473 | 24719 | all | phecode |
| 516 | Abnormal sputum | Respiratory | 0.99 | 0.947 – 1.04 | 0.657 | 2172 | 21713 | all | phecode |
| 516.1 | Hemoptysis | Respiratory | 1 | 0.958 – 1.05 | 0.902 | 2079 | 20781 | all | phecode |
| 519 |
Other diseases of respiratory system, notOther diseases of respiratory system, not elsewhere classified
|
Respiratory | 1.03 | 1.01 – 1.05 | 0.00787 | 9497 | 94944 | all | phecode |
| 519.2 | Respiratory complications | Respiratory | 1.12 | 0.996 – 1.25 | 0.0564 | 328 | 3280 | all | phecode |
| 519.8 | Other diseases of respiratory system, NEC | Respiratory | 1.03 | 1.01 – 1.05 | 0.0101 | 8881 | 88784 | all | phecode |
| 519.9 |
Symptoms involving respiratory system and otherSymptoms involving respiratory system and other chest symptoms
|
Respiratory | 0.962 | 0.853 – 1.08 | 0.52 | 305 | 3050 | all | phecode |
| 520 | Disorders of tooth development | Digestive | 1.03 | 0.99 – 1.08 | 0.141 | 2446 | 24460 | all | phecode |
| 520.1 | Hereditary disturbances in tooth structure | Digestive | 0.941 | 0.7 – 1.25 | 0.676 | 53 | 530 | all | phecode |
| 520.2 | Disturbances in tooth eruption | Digestive | 1.03 | 0.989 – 1.08 | 0.141 | 2361 | 23610 | all | phecode |
| 521 | Diseases of hard tissues of teeth | Digestive | 1.01 | 0.97 – 1.04 | 0.728 | 3087 | 30870 | all | phecode |
| 521.1 | Dental caries | Digestive | 1.01 | 0.97 – 1.05 | 0.71 | 3047 | 30470 | all | phecode |
| 522 | Diseases of pulp and periapical tissues | Digestive | 0.984 | 0.937 – 1.03 | 0.521 | 1792 | 17917 | all | phecode |
| 522.5 | Periapical abscess | Digestive | 0.98 | 0.922 – 1.04 | 0.519 | 1175 | 11750 | all | phecode |
| 523 | Gingival and periodontal diseases | Digestive | 1.01 | 0.961 – 1.06 | 0.698 | 1741 | 17410 | all | phecode |
| 523.1 | Gingivitis | Digestive | 0.997 | 0.819 – 1.21 | 0.974 | 114 | 1140 | all | phecode |
| 523.3 | Periodontitis (acute or chronic) | Digestive | 1.04 | 0.98 – 1.1 | 0.193 | 1222 | 12220 | all | phecode |
| 523.31 | Acute periodontitis | Digestive | 1.07 | 0.992 – 1.16 | 0.0774 | 668 | 6680 | all | phecode |
| 523.32 | Chronic periodontitis | Digestive | 1 | 0.918 – 1.09 | 0.959 | 561 | 5610 | all | phecode |
| 524 | Dentofacial anomalies, including malocclusion | Digestive | 1.05 | 0.941 – 1.17 | 0.369 | 345 | 3450 | all | phecode |
| 524.3 | Anomalies of tooth position/malocclusion | Digestive | 1.01 | 0.901 – 1.14 | 0.813 | 305 | 3050 | all | phecode |
| 525 |
Other diseases of the teeth and supportingOther diseases of the teeth and supporting structures
|
Digestive | 1.01 | 0.972 – 1.05 | 0.567 | 2685 | 26850 | all | phecode |
| 525.2 | Atrophy of edentulous alveolar ridge | Digestive | 1.03 | 0.803 – 1.31 | 0.826 | 72 | 720 | all | phecode |
| 526 | Diseases of the jaws | Digestive | 0.985 | 0.921 – 1.05 | 0.662 | 959 | 9590 | all | phecode |
| 526.1 | Cysts of the jaws | Digestive | 0.986 | 0.879 – 1.1 | 0.803 | 329 | 3290 | all | phecode |
| 526.3 | Anomalies of jaw size/symmetry | Digestive | 0.968 | 0.738 – 1.26 | 0.807 | 61 | 610 | all | phecode |
| 526.4 | Temporomandibular joint disorders | Digestive | 1.08 | 0.949 – 1.23 | 0.23 | 240 | 2400 | all | phecode |
| 526.41 | Temporomandibular joint disorder, unspecified | Digestive | 1.07 | 0.938 – 1.23 | 0.295 | 233 | 2330 | all | phecode |
| 526.5 | Inflammatory conditions of jaw | Digestive | 1.03 | 0.844 – 1.25 | 0.764 | 110 | 1100 | all | phecode |
| 526.9 | Jaw disease NOS | Digestive | 0.882 | 0.767 – 1.01 | 0.0728 | 234 | 2340 | all | phecode |
| 527 | Diseases of the salivary glands | Digestive | 0.962 | 0.89 – 1.04 | 0.333 | 710 | 7100 | all | phecode |
| 527.1 | Hypertrophy of salivary gland | Digestive | 0.937 | 0.744 – 1.17 | 0.569 | 84 | 840 | all | phecode |
| 527.2 | Sialoadenitis | Digestive | 0.934 | 0.837 – 1.04 | 0.219 | 366 | 3660 | all | phecode |
| 527.7 | Disturbance of salivary secretion | Digestive | 1.16 | 0.9 – 1.5 | 0.236 | 63 | 630 | all | phecode |
| 527.8 | Other specified diseases of the salivary glands | Digestive | 0.974 | 0.804 – 1.18 | 0.786 | 120 | 1200 | all | phecode |
| 528 |
Diseases of the oral soft tissues, excludingDiseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
|
Digestive | 1.02 | 0.984 – 1.05 | 0.322 | 3927 | 39270 | all | phecode |
| 528.1 | Stomatitis and mucositis | Digestive | 1.1 | 0.997 – 1.2 | 0.057 | 469 | 4690 | all | phecode |
| 528.11 | Stomatitis and mucositis (ulcerative) | Digestive | 1.13 | 1.02 – 1.26 | 0.0179 | 390 | 3900 | all | phecode |
| 528.12 | Oral aphthae | Digestive | 0.885 | 0.7 – 1.11 | 0.292 | 84 | 840 | all | phecode |
| 528.3 | Cellulitis and abscess of oral soft tissues | Digestive | 1.03 | 0.881 – 1.2 | 0.719 | 181 | 1810 | all | phecode |
| 528.4 | Cysts of oral soft tissues | Digestive | 0.804 | 0.663 – 0.972 | 0.0243 | 125 | 1250 | all | phecode |
| 528.41 | Cyst of the salivary gland | Digestive | 0.793 | 0.635 – 0.985 | 0.0359 | 94 | 940 | all | phecode |
| 528.5 | Diseases of lips | Digestive | 1.05 | 0.972 – 1.14 | 0.203 | 682 | 6820 | all | phecode |
| 528.6 | Leukoplakia of oral mucosa | Digestive | 1.05 | 0.932 – 1.18 | 0.424 | 308 | 3080 | all | phecode |
| 528.7 | Sialolithiasis | Digestive | 1.03 | 0.913 – 1.15 | 0.657 | 314 | 3140 | all | phecode |
| 529 | Diseases and other conditions of the tongue | Digestive | 0.998 | 0.941 – 1.06 | 0.946 | 1235 | 12344 | all | phecode |
| 529.1 | Glossitis | Digestive | 0.98 | 0.869 – 1.1 | 0.739 | 299 | 2990 | all | phecode |
| 530 | Diseases of esophagus | Digestive | 1.02 | 1.01 – 1.04 | 5.59e-05 | 33704 | 280049 | all | phecode |
| 530.1 | Esophagitis, GERD and related diseases | Digestive | 1.02 | 1.01 – 1.04 | 0.000154 | 31312 | 260239 | all | phecode |
| 530.11 | GERD | Digestive | 1.02 | 0.998 – 1.03 | 0.0926 | 14058 | 140580 | all | phecode |
| 530.12 | Ulcer of esophagus | Digestive | 1.05 | 1.03 – 1.09 | 0.000252 | 5219 | 52184 | all | phecode |
| 530.14 | Reflux esophagitis | Digestive | 1.01 | 0.989 – 1.03 | 0.39 | 10473 | 104727 | all | phecode |
| 530.2 | Esophageal bleeding (varices/hemorrhage) | Digestive | 1.04 | 0.987 – 1.09 | 0.147 | 1683 | 16830 | all | phecode |
| 530.3 | Stricture and stenosis of esophagus | Digestive | 0.983 | 0.937 – 1.03 | 0.492 | 1873 | 18730 | all | phecode |
| 530.5 | Disorders of esophageal motility | Digestive | 1.04 | 0.954 – 1.12 | 0.395 | 638 | 6380 | all | phecode |
| 530.6 | Diverticulum of esophagus, acquired | Digestive | 1.09 | 0.921 – 1.28 | 0.313 | 153 | 1529 | all | phecode |
| 530.7 | Gastroesophageal laceration-hemorrhage syndrome | Digestive | 1.04 | 0.929 – 1.16 | 0.493 | 344 | 3440 | all | phecode |
| 530.9 | Heartburn | Digestive | 1.06 | 1.01 – 1.11 | 0.00901 | 2096 | 20960 | all | phecode |
| 531 | Peptic ulcer (excl. esophageal) | Digestive | 1.01 | 0.982 – 1.03 | 0.632 | 7421 | 74192 | all | phecode |
| 531.1 | Hemorrhage from gastrointestinal ulcer | Digestive | 1.04 | 0.96 – 1.13 | 0.315 | 634 | 6340 | all | phecode |
| 531.2 | Gastric ulcer | Digestive | 1 | 0.968 – 1.03 | 0.998 | 4099 | 40979 | all | phecode |
| 531.3 | Duodenal ulcer | Digestive | 0.996 | 0.959 – 1.03 | 0.836 | 2994 | 29933 | all | phecode |
| 531.4 | Peptic ulcer, site unspecified | Digestive | 1.1 | 0.994 – 1.22 | 0.0638 | 424 | 4240 | all | phecode |
| 532 | Dysphagia | Digestive | 1.04 | 1.02 – 1.07 | 0.0014 | 6447 | 64466 | all | phecode |
| 535 | Gastritis and duodenitis | Digestive | 1.03 | 1.02 – 1.04 | 3.73e-06 | 28309 | 262547 | all | phecode |
| 535.1 | Acute gastritis | Digestive | 1.01 | 0.95 – 1.07 | 0.778 | 1185 | 11850 | all | phecode |
| 535.2 | Atrophic gastritis | Digestive | 1.11 | 0.996 – 1.23 | 0.0583 | 370 | 3690 | all | phecode |
| 535.6 | Duodenitis | Digestive | 1.03 | 1.01 – 1.06 | 0.0102 | 7605 | 76045 | all | phecode |
| 535.8 | Other specified gastritis | Digestive | 1.03 | 1.01 – 1.05 | 0.0119 | 8094 | 80940 | all | phecode |
| 535.9 | Gastritis and duodenitis, NOS | Digestive | 1.09 | 0.899 – 1.31 | 0.385 | 120 | 1192 | all | phecode |
| 536 | Disorders of function of stomach | Digestive | 1.02 | 0.896 – 1.16 | 0.782 | 268 | 2666 | all | phecode |
| 536.8 |
Dyspepsia and other specified disorders ofDyspepsia and other specified disorders of function of stomach
|
Digestive | 1.02 | 0.893 – 1.16 | 0.789 | 259 | 2576 | all | phecode |
| 537 | Other disorders of stomach and duodenum | Digestive | 1.04 | 1 – 1.08 | 0.0351 | 3400 | 33994 | all | phecode |
| 540 | Appendiceal conditions | Digestive | 0.98 | 0.945 – 1.02 | 0.26 | 3409 | 34084 | all | phecode |
| 540.1 | Appendicitis | Digestive | 0.979 | 0.943 – 1.02 | 0.248 | 3217 | 32164 | all | phecode |
| 540.11 | Acute appendicitis | Digestive | 0.967 | 0.928 – 1.01 | 0.104 | 2607 | 26064 | all | phecode |
| 550 | Abdominal hernia | Digestive | 1.02 | 1.01 – 1.03 | 0.000159 | 45931 | 283394 | all | phecode |
| 550.1 | Inguinal hernia | Digestive | 1.01 | 0.997 – 1.03 | 0.0956 | 15818 | 123480 | all | phecode |
| 550.2 | Diaphragmatic hernia | Digestive | 1.03 | 1.02 – 1.04 | 2.02e-05 | 26560 | 239425 | all | phecode |
| 550.3 | Femoral hernia | Digestive | 1.02 | 0.94 – 1.11 | 0.628 | 651 | 6510 | all | phecode |
| 550.4 | Umbilical hernia | Digestive | 1.01 | 0.977 – 1.05 | 0.53 | 3713 | 37130 | all | phecode |
| 550.5 | Ventral hernia | Digestive | 1.03 | 0.997 – 1.07 | 0.0695 | 3441 | 34410 | all | phecode |
| 555 |
Inflammatory bowel disease and otherInflammatory bowel disease and other gastroenteritis and colitis
|
Digestive | 1.01 | 0.979 – 1.04 | 0.533 | 4504 | 45040 | all | phecode |
| 555.1 | Regional enteritis | Digestive | 0.976 | 0.929 – 1.03 | 0.35 | 1731 | 17310 | all | phecode |
| 555.2 | Ulcerative colitis | Digestive | 1.03 | 0.993 – 1.07 | 0.118 | 3182 | 31820 | all | phecode |
| 555.21 | Ulcerative colitis (chronic) | Digestive | 1.01 | 0.919 – 1.1 | 0.912 | 538 | 5380 | all | phecode |
| 556 | Ulceration of the lower GI tract | Digestive | 1.08 | 1.01 – 1.15 | 0.0158 | 1062 | 10620 | all | phecode |
| 556.1 | Ulceration of intestine | Digestive | 1.06 | 0.977 – 1.15 | 0.161 | 673 | 6730 | all | phecode |
| 557 | Intestinal malabsorption (non-celiac) | Digestive | 0.934 | 0.828 – 1.05 | 0.266 | 301 | 3010 | all | phecode |
| 558 | Noninfectious gastroenteritis | Digestive | 1.02 | 1 – 1.04 | 0.0203 | 15594 | 155922 | all | phecode |
| 559 | Ileostomy status | Digestive | 1.02 | 0.967 – 1.07 | 0.505 | 1659 | 16590 | all | phecode |
| 560 | Intestinal obstruction without mention of hernia | Digestive | 1.05 | 1.01 – 1.08 | 0.00511 | 4006 | 40053 | all | phecode |
| 560.1 | Paralytic ileus | Digestive | 1.09 | 0.994 – 1.19 | 0.0646 | 523 | 5230 | all | phecode |
| 560.2 | Impaction of intestine | Digestive | 1.01 | 0.892 – 1.15 | 0.836 | 268 | 2680 | all | phecode |
| 560.3 | Peritoneal or intestinal adhesions | Digestive | 1.09 | 1.02 – 1.17 | 0.0167 | 831 | 8310 | all | phecode |
| 560.4 | Other intestinal obstruction | Digestive | 1.04 | 1.01 – 1.08 | 0.0212 | 3362 | 33616 | all | phecode |
| 561 | Symptoms involving digestive system | Digestive | 1 | 0.987 – 1.02 | 0.725 | 15809 | 158086 | all | phecode |
| 561.1 | Diarrhea | Digestive | 1.07 | 0.97 – 1.17 | 0.179 | 466 | 4660 | all | phecode |
| 561.2 | Flatulence | Digestive | 1 | 0.953 – 1.05 | 0.931 | 1688 | 16880 | all | phecode |
| 562 | Diverticulosis and diverticulitis | Digestive | 1.02 | 1.01 – 1.03 | 0.00514 | 26751 | 211994 | all | phecode |
| 562.1 | Diverticulosis | Digestive | 1.02 | 1.01 – 1.03 | 0.00513 | 26709 | 211935 | all | phecode |
| 563 | Constipation | Digestive | 1 | 0.984 – 1.02 | 0.712 | 10350 | 103421 | all | phecode |
| 564 | Functional digestive disorders | Digestive | 1.02 | 1.01 – 1.03 | 0.00691 | 21783 | 210993 | all | phecode |
| 564.1 | Irritable Bowel Syndrome | Digestive | 1.02 | 0.987 – 1.04 | 0.287 | 5522 | 55220 | all | phecode |
| 564.8 |
Abnormal findings on exam of gastrointestinalAbnormal findings on exam of gastrointestinal tract/ abdominal area
|
Digestive | 0.998 | 0.948 – 1.05 | 0.926 | 1649 | 16490 | all | phecode |
| 564.9 | Personal history of diseases of digestive system | Digestive | 1.02 | 1.01 – 1.04 | 0.00447 | 15221 | 151974 | all | phecode |
| 565 | Anal and rectal conditions | Digestive | 1.02 | 0.998 – 1.03 | 0.0795 | 14862 | 148609 | all | phecode |
| 565.1 | Anal and rectal polyp | Digestive | 1.02 | 0.998 – 1.05 | 0.0714 | 7341 | 73408 | all | phecode |
| 567 | Peritonitis and retroperitoneal infections | Digestive | 1 | 0.934 – 1.07 | 0.991 | 932 | 9320 | all | phecode |
| 568 | Other disorders of peritoneum | Digestive | 1.02 | 0.984 – 1.06 | 0.274 | 3309 | 33090 | all | phecode |
| 568.1 |
Peritoneal adhesions (postoperative)Peritoneal adhesions (postoperative) (postinfection)
|
Digestive | 1.02 | 0.983 – 1.06 | 0.292 | 3102 | 31020 | all | phecode |
| 569 | Other disorders of intestine | Digestive | 1.01 | 0.979 – 1.04 | 0.522 | 4218 | 42180 | all | phecode |
| 569.1 | Toxic gastroenteritis and colitis | Digestive | 1.12 | 0.946 – 1.32 | 0.184 | 149 | 1490 | all | phecode |
| 569.2 | Gastrointestinal complications | Digestive | 0.989 | 0.9 – 1.09 | 0.817 | 484 | 4840 | all | phecode |
| 571 | Chronic liver disease and cirrhosis | Digestive | 1.08 | 1.04 – 1.12 | 9.12e-05 | 2984 | 29840 | all | phecode |
| 571.5 | Other chronic nonalcoholic liver disease | Digestive | 1.06 | 1.01 – 1.12 | 0.0135 | 1699 | 16990 | all | phecode |
| 571.51 | Cirrhosis of liver without mention of alcohol | Digestive | 0.839 | 0.687 – 1.02 | 0.0804 | 115 | 1150 | all | phecode |
| 571.6 | Primary biliary cirrhosis | Digestive | 1.13 | 0.99 – 1.28 | 0.068 | 256 | 2560 | all | phecode |
| 571.8 |
Liver abscess and sequelae of chronic liverLiver abscess and sequelae of chronic liver disease
|
Digestive | 1.08 | 1.01 – 1.15 | 0.0246 | 987 | 9870 | all | phecode |
| 571.81 | Portal hypertension | Digestive | 1.1 | 1 – 1.2 | 0.0454 | 532 | 5320 | all | phecode |
| 572 | Ascites (non malignant) | Digestive | 1.01 | 0.956 – 1.06 | 0.779 | 1548 | 15480 | all | phecode |
| 573 | Other disorders of liver | Digestive | 1.02 | 0.966 – 1.07 | 0.492 | 1505 | 15045 | all | phecode |
| 573.5 | Jaundice (not of newborn) | Digestive | 0.874 | 0.662 – 1.15 | 0.328 | 59 | 590 | all | phecode |
| 573.7 | Abnormal results of function study of liver | Digestive | 1.06 | 0.901 – 1.25 | 0.464 | 156 | 1555 | all | phecode |
| 574 | Cholelithiasis and cholecystitis | Digestive | 1.03 | 1.01 – 1.04 | 0.000966 | 16011 | 160020 | all | phecode |
| 574.1 | Cholelithiasis | Digestive | 1.02 | 1.01 – 1.04 | 0.00769 | 13618 | 136158 | all | phecode |
| 574.11 | Cholelithiasis with acute cholecystitis | Digestive | 1.07 | 1.01 – 1.12 | 0.0186 | 1511 | 15110 | all | phecode |
| 574.12 | Cholelithiasis with other cholecystitis | Digestive | 1.02 | 0.99 – 1.05 | 0.21 | 5437 | 54370 | all | phecode |
| 574.2 | Calculus of bile duct | Digestive | 1 | 0.96 – 1.04 | 0.986 | 2627 | 26264 | all | phecode |
| 574.3 | Cholecystitis without cholelithiasis | Digestive | 1.04 | 0.995 – 1.08 | 0.0824 | 2759 | 27590 | all | phecode |
| 575 | Other biliary tract disease | Digestive | 1.02 | 0.991 – 1.06 | 0.16 | 3897 | 38970 | all | phecode |
| 575.1 | Cholangitis | Digestive | 0.985 | 0.897 – 1.08 | 0.751 | 495 | 4950 | all | phecode |
| 575.2 | Obstruction of bile duct | Digestive | 0.999 | 0.927 – 1.08 | 0.981 | 777 | 7770 | all | phecode |
| 575.6 | Cholesterolosis of gallbladder | Digestive | 1.04 | 0.945 – 1.15 | 0.414 | 457 | 4570 | all | phecode |
| 575.7 | Other disorders of gallbladder | Digestive | 1.08 | 1.02 – 1.14 | 0.00507 | 1410 | 14100 | all | phecode |
| 575.8 | Other disorders of biliary tract | Digestive | 1.02 | 0.957 – 1.09 | 0.535 | 1037 | 10370 | all | phecode |
| 575.9 |
Nonspecific abnormal findings on radiologicalNonspecific abnormal findings on radiological and other examination of biliary tract
|
Digestive | 0.973 | 0.87 – 1.09 | 0.63 | 349 | 3490 | all | phecode |
| 577 | Diseases of pancreas | Digestive | 1.03 | 0.993 – 1.08 | 0.108 | 2702 | 27020 | all | phecode |
| 577.1 | Acute pancreatitis | Digestive | 1.05 | 1 – 1.1 | 0.0401 | 1996 | 19960 | all | phecode |
| 577.2 | Chronic pancreatitis | Digestive | 1.05 | 0.956 – 1.15 | 0.315 | 514 | 5140 | all | phecode |
| 577.3 | Cyst and pseudocyst of pancreas | Digestive | 1.03 | 0.922 – 1.15 | 0.608 | 363 | 3630 | all | phecode |
| 578 | Gastrointestinal hemorrhage | Digestive | 1.02 | 1.01 – 1.04 | 0.00238 | 20901 | 208958 | all | phecode |
| 578.1 | Hematemesis | Digestive | 1.08 | 1.03 – 1.13 | 0.00202 | 1941 | 19396 | all | phecode |
| 578.2 | Blood in stool | Digestive | 1.02 | 0.982 – 1.06 | 0.286 | 2597 | 25956 | all | phecode |
| 578.8 | Hemorrhage of rectum and anus | Digestive | 1.03 | 1.01 – 1.05 | 0.00395 | 13031 | 130279 | all | phecode |
| 578.9 | Hemorrhage of gastrointestinal tract | Digestive | 1.02 | 0.99 – 1.05 | 0.206 | 5292 | 52920 | all | phecode |
| 579 | Other symptoms involving abdomen and pelvis | Digestive | 0.986 | 0.935 – 1.04 | 0.608 | 1553 | 15530 | all | phecode |
| 579.2 | Splenomegaly | Digestive | 1 | 0.908 – 1.11 | 0.933 | 426 | 4260 | all | phecode |
| 580 | Nephritis; nephrosis; renal sclerosis | Genitourinary | 1.02 | 0.965 – 1.07 | 0.519 | 1556 | 15560 | all | phecode |
| 580.1 | Glomerulonephritis | Genitourinary | 1.02 | 0.953 – 1.08 | 0.642 | 1069 | 10690 | all | phecode |
| 580.11 | Proliferative glomerulonephritis | Genitourinary | 1.05 | 0.829 – 1.32 | 0.689 | 79 | 790 | all | phecode |
| 580.12 | Non-proliferative glomerulonephritis | Genitourinary | 0.994 | 0.83 – 1.19 | 0.949 | 136 | 1360 | all | phecode |
| 580.14 | Chronic glomerulonephritis, NOS | Genitourinary | 1.01 | 0.942 – 1.08 | 0.772 | 881 | 8810 | all | phecode |
| 580.2 |
Nephrotic syndrome without mention ofNephrotic syndrome without mention of glomerulonephritis
|
Genitourinary | 1.05 | 0.957 – 1.16 | 0.285 | 469 | 4690 | all | phecode |
| 580.3 |
Nephritis and nephropathy without mention ofNephritis and nephropathy without mention of glomerulonephritis
|
Genitourinary | 0.981 | 0.86 – 1.12 | 0.778 | 253 | 2530 | all | phecode |
| 580.32 |
Nephritis and nephropathy with pathologicalNephritis and nephropathy with pathological lesion
|
Genitourinary | 0.981 | 0.86 – 1.12 | 0.778 | 253 | 2530 | all | phecode |
| 585 | Renal failure | Genitourinary | 1.01 | 0.981 – 1.03 | 0.67 | 7013 | 70119 | all | phecode |
| 585.1 | Acute renal failure | Genitourinary | 0.986 | 0.956 – 1.02 | 0.356 | 4537 | 45366 | all | phecode |
| 585.2 | Renal failure NOS | Genitourinary | 1.04 | 0.982 – 1.09 | 0.193 | 1466 | 14657 | all | phecode |
| 585.3 | Chronic renal failure [CKD] | Genitourinary | 1.02 | 0.981 – 1.06 | 0.301 | 2652 | 26514 | all | phecode |
| 585.31 | Renal dialysis | Genitourinary | 1.05 | 0.955 – 1.15 | 0.314 | 494 | 4940 | all | phecode |
| 586 | Other disorders of the kidney and ureters | Genitourinary | 1.03 | 0.992 – 1.07 | 0.122 | 3382 | 33819 | all | phecode |
| 586.1 | Anatomical abnormatilies of kidney and ureters | Genitourinary | 0.991 | 0.86 – 1.14 | 0.895 | 215 | 2150 | all | phecode |
| 586.11 | Small kidney | Genitourinary | 0.949 | 0.812 – 1.11 | 0.505 | 180 | 1800 | all | phecode |
| 586.2 | Cyst of kidney, acquired | Genitourinary | 1.01 | 0.951 – 1.07 | 0.774 | 1258 | 12579 | all | phecode |
| 586.3 | Vascular disorders of kidney/hypertrophy | Genitourinary | 1.07 | 0.848 – 1.34 | 0.568 | 80 | 800 | all | phecode |
| 586.4 | Stricture/obstruction of ureter | Genitourinary | 1.04 | 0.968 – 1.11 | 0.295 | 916 | 9160 | all | phecode |
| 587 | Kidney replaced by transpant | Genitourinary | 1.06 | 0.949 – 1.18 | 0.311 | 369 | 3690 | all | phecode |
| 588 | Disorders resulting from impaired renal function | Genitourinary | 1.05 | 0.852 – 1.29 | 0.639 | 99 | 990 | all | phecode |
| 589 | Abnormal results of function study of kidney | Genitourinary | 0.896 | 0.735 – 1.09 | 0.266 | 117 | 1170 | all | phecode |
| 590 | Pyelonephritis | Genitourinary | 0.999 | 0.944 – 1.06 | 0.977 | 1331 | 13310 | all | phecode |
| 591 | Urinary tract infection | Genitourinary | 1.01 | 0.987 – 1.02 | 0.561 | 12432 | 124264 | all | phecode |
| 592 | Cystitis and urethritis | Genitourinary | 1.01 | 0.974 – 1.05 | 0.55 | 3076 | 30754 | all | phecode |
| 592.1 | Cystitis | Genitourinary | 1.01 | 0.974 – 1.05 | 0.545 | 2936 | 29354 | all | phecode |
| 592.11 | Acute cystitis | Genitourinary | 1.06 | 0.89 – 1.27 | 0.495 | 137 | 1370 | all | phecode |
| 592.12 | Chronic cystitis | Genitourinary | 0.98 | 0.914 – 1.05 | 0.564 | 889 | 8890 | all | phecode |
| 592.13 | Chronic interstitial cystitis | Genitourinary | 1.01 | 0.884 – 1.15 | 0.888 | 247 | 2470 | all | phecode |
| 592.2 | Urethritis and urethral syndrome | Genitourinary | 0.993 | 0.844 – 1.17 | 0.931 | 167 | 1670 | all | phecode |
| 593 | Hematuria | Genitourinary | 1.02 | 1.01 – 1.04 | 0.00411 | 16202 | 161323 | all | phecode |
| 594 | Urinary calculus | Genitourinary | 1.02 | 0.997 – 1.05 | 0.0905 | 6612 | 66119 | all | phecode |
| 594.1 | Calculus of kidney | Genitourinary | 1.02 | 0.986 – 1.06 | 0.219 | 3176 | 31760 | all | phecode |
| 594.2 | Calculus of lower urinary tract | Genitourinary | 1.03 | 0.959 – 1.11 | 0.383 | 776 | 7760 | all | phecode |
| 594.3 | Calculus of ureter | Genitourinary | 1.02 | 0.981 – 1.07 | 0.29 | 2403 | 24029 | all | phecode |
| 594.8 | Renal colic | Genitourinary | 1.01 | 0.967 – 1.06 | 0.582 | 2045 | 20449 | all | phecode |
| 595 | Hydronephrosis | Genitourinary | 1.01 | 0.963 – 1.06 | 0.686 | 1953 | 19530 | all | phecode |
| 596 | Other disorders of bladder | Genitourinary | 1.01 | 0.99 – 1.03 | 0.3 | 9856 | 98560 | all | phecode |
| 596.1 | Bladder neck obstruction | Genitourinary | 1.01 | 0.968 – 1.06 | 0.533 | 1963 | 19630 | all | phecode |
| 596.5 | Functional disorders of bladder | Genitourinary | 1.06 | 1 – 1.11 | 0.0351 | 1653 | 16530 | all | phecode |
| 597 | Other disorders of urethra and urinary tract | Genitourinary | 1.01 | 0.975 – 1.04 | 0.641 | 3984 | 39834 | all | phecode |
| 597.1 | Urethral stricture (not specified as infectious) | Genitourinary | 0.998 | 0.963 – 1.03 | 0.918 | 3322 | 33214 | all | phecode |
| 598 | Abnormal findings on examination of urine | Genitourinary | 1.01 | 0.976 – 1.05 | 0.542 | 3538 | 35378 | all | phecode |
| 598.9 |
Other nonspecific findings on examination ofOther nonspecific findings on examination of urine
|
Genitourinary | 1.14 | 1.01 – 1.28 | 0.0276 | 304 | 3040 | all | phecode |
| 599 | Other symptoms/disorders or the urinary system | Genitourinary | 1.01 | 0.991 – 1.02 | 0.437 | 18729 | 187237 | all | phecode |
| 599.1 | Urinary obstruction | Genitourinary | 0.941 | 0.8 – 1.11 | 0.46 | 167 | 1670 | all | phecode |
| 599.2 | Retention of urine | Genitourinary | 1 | 0.976 – 1.03 | 0.912 | 6733 | 67330 | all | phecode |
| 599.3 | Dysuria | Genitourinary | 1.02 | 0.962 – 1.08 | 0.491 | 1199 | 11990 | all | phecode |
| 599.4 | Urinary incontinence | Genitourinary | 1.01 | 0.984 – 1.03 | 0.609 | 8766 | 87659 | all | phecode |
| 599.5 | Frequency of urination and polyuria | Genitourinary | 0.992 | 0.96 – 1.02 | 0.616 | 4023 | 40230 | all | phecode |
| 599.6 | Oliguria and anuria | Genitourinary | 1.21 | 0.997 – 1.48 | 0.0511 | 107 | 1070 | all | phecode |
| 599.8 | Other symptoms involving urinary system | Genitourinary | 0.985 | 0.787 – 1.23 | 0.896 | 87 | 870 | all | phecode |
| 599.9 | Other abnormality of urination | Genitourinary | 1.04 | 0.988 – 1.09 | 0.144 | 1921 | 19210 | all | phecode |
| 600 | Hyperplasia of prostate | Genitourinary | 1 | 0.985 – 1.03 | 0.636 | 11123 | 87742 | all | phecode |
| 601 | Inflammatory diseases of prostate | Genitourinary | 0.984 | 0.941 – 1.03 | 0.469 | 2188 | 21880 | all | phecode |
| 601.1 | Prostatitis | Genitourinary | 0.991 | 0.94 – 1.04 | 0.721 | 1576 | 15760 | all | phecode |
| 601.11 | Acute prostatitis | Genitourinary | 0.953 | 0.831 – 1.09 | 0.488 | 235 | 2350 | all | phecode |
| 601.12 | Chronic prostatitis | Genitourinary | 1 | 0.934 – 1.07 | 0.99 | 910 | 9100 | all | phecode |
| 601.3 | Orchitis and epididymitis | Genitourinary | 1.21 | 0.923 – 1.6 | 0.159 | 59 | 590 | all | phecode |
| 601.4 | Balanoposthitis | Genitourinary | 0.92 | 0.812 – 1.04 | 0.183 | 286 | 2860 | all | phecode |
| 601.8 |
Other inflammatory disorders of male genitalOther inflammatory disorders of male genital organs
|
Genitourinary | 0.976 | 0.866 – 1.1 | 0.694 | 303 | 3030 | all | phecode |
| 602 | Other disorders of prostate | Genitourinary | 0.943 | 0.891 – 0.998 | 0.044 | 1343 | 13430 | all | phecode |
| 603 | Other disorders of testis | Genitourinary | 1.01 | 0.966 – 1.06 | 0.661 | 2192 | 21912 | all | phecode |
| 603.1 | Hydrocele | Genitourinary | 0.972 | 0.919 – 1.03 | 0.336 | 1340 | 13400 | all | phecode |
| 604 | Disorders of penis | Genitourinary | 0.961 | 0.927 – 0.996 | 0.0303 | 3412 | 34093 | all | phecode |
| 604.1 | Redundant prepuce and phimosis/BXO | Genitourinary | 0.962 | 0.925 – 1 | 0.0541 | 2853 | 28505 | all | phecode |
| 605 | Erectile dysfunction [ED] | Genitourinary | 1 | 0.886 – 1.14 | 0.946 | 280 | 2800 | all | phecode |
| 608 | Other disorders of male genital organs | Genitourinary | 0.99 | 0.952 – 1.03 | 0.608 | 2826 | 28259 | all | phecode |
| 609 | Male infertility and abnormal spermatozoa | Genitourinary | 0.937 | 0.816 – 1.07 | 0.349 | 233 | 2330 | all | phecode |
| 609.1 | Infertility, male | Genitourinary | 0.842 | 0.646 – 1.09 | 0.194 | 64 | 640 | all | phecode |
| 609.2 | Abnormal spermatozoa | Genitourinary | 0.973 | 0.828 – 1.14 | 0.731 | 170 | 1700 | all | phecode |
| 610 | Benign mammary dysplasias | Genitourinary | 1.03 | 0.989 – 1.07 | 0.158 | 2838 | 28379 | all | phecode |
| 610.1 | Cystic mastopathy | Genitourinary | 1.12 | 1.05 – 1.2 | 0.000735 | 923 | 9229 | all | phecode |
| 610.2 | Fibroadenosis of breast | Genitourinary | 0.943 | 0.836 – 1.06 | 0.334 | 306 | 3060 | all | phecode |
| 610.3 | Fibrosclerosis of breast | Genitourinary | 1.03 | 0.911 – 1.16 | 0.659 | 301 | 3010 | all | phecode |
| 610.4 | Benign neoplasm of breast | Genitourinary | 1 | 0.951 – 1.06 | 0.933 | 1548 | 15479 | all | phecode |
| 610.8 | Other specified benign mammary dysplasias | Genitourinary | 0.995 | 0.846 – 1.17 | 0.951 | 165 | 1650 | all | phecode |
| 611 | Abnormal findings on mammogram or breast exam | Genitourinary | 1.02 | 0.972 – 1.08 | 0.375 | 1578 | 15780 | all | phecode |
| 611.1 | Abnormal mammogram | Genitourinary | 1.1 | 0.834 – 1.44 | 0.493 | 57 | 570 | all | phecode |
| 611.3 | Lump or mass in breast | Genitourinary | 1.02 | 0.967 – 1.08 | 0.475 | 1523 | 15230 | all | phecode |
| 612 |
Breast conditions, congenital or relating toBreast conditions, congenital or relating to hormones
|
Genitourinary | 0.992 | 0.927 – 1.06 | 0.811 | 939 | 9390 | all | phecode |
| 612.2 | Hypertrophy of breast (Gynecomastia) | Genitourinary | 1 | 0.931 – 1.07 | 0.995 | 851 | 8510 | all | phecode |
| 612.3 | Congenital anomalies of breast | Genitourinary | 0.884 | 0.696 – 1.12 | 0.299 | 78 | 780 | all | phecode |
| 613 | Other nonmalignant breast conditions | Genitourinary | 1.07 | 1.02 – 1.12 | 0.00423 | 1981 | 19796 | all | phecode |
| 613.1 | Inflammatory disease of breast | Genitourinary | 1.07 | 0.988 – 1.15 | 0.0961 | 721 | 7205 | all | phecode |
| 613.5 | Mastodynia | Genitourinary | 1.01 | 0.792 – 1.27 | 0.964 | 77 | 770 | all | phecode |
| 613.7 | Other signs and symptoms in breast | Genitourinary | 1.09 | 1.01 – 1.18 | 0.0243 | 704 | 7031 | all | phecode |
| 613.8 | Other specified disorders of breast | Genitourinary | 1.07 | 0.957 – 1.2 | 0.221 | 328 | 3280 | all | phecode |
| 613.9 | Breast disorder NOS | Genitourinary | 1.07 | 0.926 – 1.23 | 0.353 | 207 | 2070 | all | phecode |
| 614 | Inflammatory diseases of female pelvic organs | Genitourinary | 1.02 | 0.992 – 1.05 | 0.172 | 6180 | 61800 | all | phecode |
| 614.1 |
Pelvic peritoneal adhesions, femalePelvic peritoneal adhesions, female (postoperative) (postinfection)
|
Genitourinary | 1.02 | 0.98 – 1.06 | 0.315 | 2538 | 25380 | all | phecode |
| 614.3 | Pelvic inflammatory disease (PID) | Genitourinary | 1.04 | 0.973 – 1.11 | 0.238 | 934 | 9340 | all | phecode |
| 614.31 | Acute inflammatory pelvic disease | Genitourinary | 1.23 | 0.946 – 1.59 | 0.117 | 61 | 610 | all | phecode |
| 614.32 | Chronic inflammatory pelvic disease | Genitourinary | 1.04 | 0.937 – 1.15 | 0.486 | 422 | 4220 | all | phecode |
| 614.33 | Pelvic inflammatory disease, NOS | Genitourinary | 1.01 | 0.908 – 1.13 | 0.797 | 352 | 3520 | all | phecode |
| 614.4 | Inflammatory diseases of uterus, except cervix | Genitourinary | 0.963 | 0.849 – 1.09 | 0.55 | 278 | 2780 | all | phecode |
| 614.5 |
Inflammatory disease of cervix, vagina, andInflammatory disease of cervix, vagina, and vulva
|
Genitourinary | 1.02 | 0.978 – 1.06 | 0.39 | 2850 | 28500 | all | phecode |
| 614.51 | Cervicitis and endocervicitis | Genitourinary | 1.01 | 0.95 – 1.07 | 0.84 | 1317 | 13170 | all | phecode |
| 614.52 | Vaginitis and vulvovaginitis | Genitourinary | 1.03 | 0.931 – 1.14 | 0.566 | 426 | 4260 | all | phecode |
| 614.53 | Cyst or abscess of Bartholin's gland | Genitourinary | 0.988 | 0.915 – 1.07 | 0.751 | 754 | 7540 | all | phecode |
| 614.54 | Abscess or ulceration of vulva | Genitourinary | 1.05 | 0.927 – 1.19 | 0.439 | 274 | 2740 | all | phecode |
| 615 | Endometriosis | Genitourinary | 1.01 | 0.974 – 1.04 | 0.687 | 4035 | 40341 | all | phecode |
| 617 |
Disorders secondary to childbirth, surgeryDisorders secondary to childbirth, surgery, trauma
|
Genitourinary | 1.08 | 0.958 – 1.21 | 0.207 | 305 | 3050 | all | phecode |
| 618 | Genital prolapse | Genitourinary | 1 | 0.983 – 1.02 | 0.87 | 11829 | 118039 | all | phecode |
| 618.1 | Prolapse of vaginal walls | Genitourinary | 1.02 | 0.992 – 1.04 | 0.199 | 7403 | 74030 | all | phecode |
| 618.2 | Uterine/Uterovaginal prolapse | Genitourinary | 0.982 | 0.955 – 1.01 | 0.221 | 5397 | 53970 | all | phecode |
| 618.5 | Prolapse of vaginal vault after hysterectomy | Genitourinary | 1.04 | 0.954 – 1.14 | 0.345 | 513 | 5130 | all | phecode |
| 618.6 | Vaginal enterocele, congenital or acquired | Genitourinary | 1.04 | 0.957 – 1.12 | 0.377 | 680 | 6800 | all | phecode |
| 619 | Noninflammatory female genital disorders | Genitourinary | 1.02 | 0.996 – 1.04 | 0.119 | 9258 | 92573 | all | phecode |
| 619.1 |
Noninflammatory disorders of ovary, fallopianNoninflammatory disorders of ovary, fallopian tube, and broad ligament
|
Genitourinary | 1.02 | 0.947 – 1.1 | 0.569 | 722 | 7220 | all | phecode |
| 619.2 | Disorders of uterus, NEC | Genitourinary | 1.01 | 0.978 – 1.05 | 0.468 | 3312 | 33120 | all | phecode |
| 619.3 | Noninflammatory disorders of cervix | Genitourinary | 1.01 | 0.97 – 1.05 | 0.667 | 2852 | 28513 | all | phecode |
| 619.4 | Noninflammatory disorders of vagina | Genitourinary | 1.02 | 0.97 – 1.07 | 0.457 | 1764 | 17640 | all | phecode |
| 619.5 | Noninflammatory disorders of vulva and perineum | Genitourinary | 1.03 | 0.977 – 1.09 | 0.246 | 1342 | 13420 | all | phecode |
| 620 | Dysplasia of female genital organs | Genitourinary | 0.91 | 0.708 – 1.16 | 0.451 | 72 | 720 | all | phecode |
| 621 | Endometrial hyperplasia | Genitourinary | 1.02 | 0.959 – 1.08 | 0.54 | 1132 | 11320 | all | phecode |
| 622 | Polyp of female genital organs | Genitourinary | 1.03 | 1.01 – 1.05 | 0.00227 | 10804 | 108040 | all | phecode |
| 622.1 | Polyp of corpus uteri | Genitourinary | 1.02 | 0.998 – 1.05 | 0.0719 | 7854 | 78540 | all | phecode |
| 622.2 | Mucous polyp of cervix | Genitourinary | 1.08 | 1.04 – 1.12 | 3.68e-05 | 3422 | 34220 | all | phecode |
| 623 | Hypertrophy of female genital organs | Genitourinary | 1 | 0.947 – 1.06 | 0.887 | 1270 | 12700 | all | phecode |
| 624 | Symptoms involving female genital tract | Genitourinary | 1 | 0.932 – 1.08 | 0.938 | 810 | 8095 | all | phecode |
| 624.1 | Dystrophy of female genital tract | Genitourinary | 0.935 | 0.816 – 1.07 | 0.331 | 237 | 2370 | all | phecode |
| 624.2 | Atrophy of female genital tract | Genitourinary | 1.05 | 0.955 – 1.16 | 0.294 | 441 | 4410 | all | phecode |
| 625 |
Pain and other symptoms associated with femalePain and other symptoms associated with female genital organs
|
Genitourinary | 1.04 | 1 – 1.08 | 0.0427 | 2996 | 29960 | all | phecode |
| 625.1 | Dyspareunia | Genitourinary | 1.05 | 0.988 – 1.11 | 0.116 | 1188 | 11880 | all | phecode |
| 626 |
Disorders of menstruation and other abnormalDisorders of menstruation and other abnormal bleeding from female genital tract
|
Genitourinary | 1.01 | 0.995 – 1.03 | 0.168 | 18324 | 129160 | all | phecode |
| 626.1 | Irregular menstrual cycle/bleeding | Genitourinary | 1.01 | 0.99 – 1.02 | 0.404 | 15686 | 122281 | all | phecode |
| 626.11 | Absent or infrequent menstruation | Genitourinary | 1.12 | 0.94 – 1.32 | 0.203 | 144 | 1440 | all | phecode |
| 626.12 | Excessive or frequent menstruation | Genitourinary | 1.01 | 0.993 – 1.04 | 0.176 | 9734 | 91841 | all | phecode |
| 626.13 | Irregular menstrual cycle | Genitourinary | 1 | 0.958 – 1.05 | 0.873 | 1985 | 19849 | all | phecode |
| 626.14 | Irregular menstrual bleeding | Genitourinary | 0.991 | 0.959 – 1.03 | 0.619 | 3809 | 38080 | all | phecode |
| 626.2 | Dysmenorrhea | Genitourinary | 0.976 | 0.929 – 1.03 | 0.337 | 1781 | 17801 | all | phecode |
| 626.4 | Premenstrual tension syndromes | Genitourinary | 0.972 | 0.822 – 1.15 | 0.738 | 159 | 1588 | all | phecode |
| 626.8 | Infertility, female | Genitourinary | 1.07 | 1.01 – 1.13 | 0.0217 | 1366 | 13624 | all | phecode |
| 627 | Menopausal and postmenopausal disorders | Genitourinary | 1.01 | 0.992 – 1.03 | 0.236 | 10631 | 106298 | all | phecode |
| 627.1 | Postmenopausal bleeding | Genitourinary | 1.01 | 0.993 – 1.04 | 0.19 | 9055 | 90540 | all | phecode |
| 627.2 | Symptomatic menopause | Genitourinary | 0.893 | 0.764 – 1.04 | 0.147 | 184 | 1839 | all | phecode |
| 627.3 | Postmenopausal atrophic vaginitis | Genitourinary | 0.999 | 0.938 – 1.06 | 0.969 | 1114 | 11140 | all | phecode |
| 627.4 | Premenopausal menorrhagia | Genitourinary | 0.965 | 0.857 – 1.09 | 0.553 | 311 | 3110 | all | phecode |
| 628 | Ovarian cyst | Genitourinary | 1.04 | 1.01 – 1.07 | 0.0209 | 4755 | 47550 | all | phecode |
| 634 | Miscarriage; stillbirth | Pregnancy Complications | 1.02 | 0.99 – 1.05 | 0.197 | 5450 | 38533 | all | phecode |
| 634.1 | Missed abortion/Hydatidiform mole | Pregnancy Complications | 1.05 | 0.988 – 1.11 | 0.123 | 1251 | 12453 | all | phecode |
| 634.3 | Ectopic pregnancy | Pregnancy Complications | 1.03 | 0.917 – 1.15 | 0.628 | 331 | 3307 | all | phecode |
| 635 |
Hemorrhage during pregnancy; childbirth andHemorrhage during pregnancy; childbirth and postpartum
|
Pregnancy Complications | 1.02 | 0.976 – 1.07 | 0.347 | 2003 | 17602 | all | phecode |
| 635.2 |
Antepartum hemorrhage, abruptio placentae, andAntepartum hemorrhage, abruptio placentae, and placenta previa
|
Pregnancy Complications | 1.02 | 0.952 – 1.09 | 0.56 | 866 | 8626 | all | phecode |
| 635.3 | Placenta previa and abruptio placenta | Pregnancy Complications | 1.04 | 0.978 – 1.1 | 0.229 | 1273 | 12329 | all | phecode |
| 636 |
Early or threatened labor; hemorrhage in earlyEarly or threatened labor; hemorrhage in early pregnancy
|
Pregnancy Complications | 0.993 | 0.952 – 1.03 | 0.722 | 2553 | 22013 | all | phecode |
| 636.2 | Early onset of delivery | Pregnancy Complications | 0.987 | 0.907 – 1.07 | 0.755 | 617 | 6155 | all | phecode |
| 636.3 | Hemorrhage in early pregnancy | Pregnancy Complications | 1 | 0.941 – 1.07 | 0.936 | 1082 | 10774 | all | phecode |
| 638 | Other high-risk pregnancy | Pregnancy Complications | 0.927 | 0.719 – 1.19 | 0.548 | 70 | 700 | all | phecode |
| 642 |
Hypertension complicating pregnancyHypertension complicating pregnancy, childbirth, and the puerperium
|
Pregnancy Complications | 0.962 | 0.903 – 1.02 | 0.22 | 1112 | 11107 | all | phecode |
| 642.1 | Preeclampsia and eclampsia | Pregnancy Complications | 1.02 | 0.909 – 1.15 | 0.696 | 307 | 3063 | all | phecode |
| 643 | Excessive vomiting in pregnancy | Pregnancy Complications | 1.24 | 1.08 – 1.42 | 0.00164 | 230 | 2299 | all | phecode |
| 643.1 | Hyperemesis gravidarum | Pregnancy Complications | 1.16 | 0.984 – 1.37 | 0.0737 | 153 | 1529 | all | phecode |
| 645 | Late pregnancy and failed induction | Pregnancy Complications | 1.02 | 0.965 – 1.08 | 0.45 | 1253 | 12474 | all | phecode |
| 646 | Other complications of pregnancy NEC | Pregnancy Complications | 0.973 | 0.931 – 1.02 | 0.221 | 2230 | 20875 | all | phecode |
| 647 |
Infectious and parasitic complicationsInfectious and parasitic complications affecting pregnancy
|
Pregnancy Complications | 0.87 | 0.671 – 1.12 | 0.279 | 68 | 680 | all | phecode |
| 649 |
Other conditions or status of the motherOther conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
|
Pregnancy Complications | 0.978 | 0.803 – 1.19 | 0.823 | 113 | 1130 | all | phecode |
| 650 | Normal delivery | Pregnancy Complications | 0.987 | 0.941 – 1.03 | 0.585 | 1925 | 19003 | all | phecode |
| 651 | Multiple gestation | Pregnancy Complications | 1 | 0.896 – 1.12 | 0.97 | 346 | 3460 | all | phecode |
| 652 |
Malposition and malpresentation of fetus orMalposition and malpresentation of fetus or obstruction
|
Pregnancy Complications | 1.03 | 0.976 – 1.08 | 0.319 | 1718 | 16535 | all | phecode |
| 653 |
Problems associated with amniotic cavity andProblems associated with amniotic cavity and membranes
|
Pregnancy Complications | 0.983 | 0.93 – 1.04 | 0.545 | 1401 | 13662 | all | phecode |
| 654 |
Other and unspecified complications of birthOther and unspecified complications of birth; puerperium affecting management of mother
|
Pregnancy Complications | 1.12 | 0.88 – 1.42 | 0.345 | 74 | 740 | all | phecode |
| 655 |
Known or suspected fetal abnormality affectingKnown or suspected fetal abnormality affecting management of mother
|
Pregnancy Complications | 0.97 | 0.938 – 1 | 0.0643 | 4309 | 29472 | all | phecode |
| 656 | Other perinatal conditions of fetus or newborn | Pregnancy Complications | 0.918 | 0.751 – 1.12 | 0.394 | 110 | 1090 | all | phecode |
| 661 | Fetal distress and abnormal forces of labor | Pregnancy Complications | 0.952 | 0.911 – 0.996 | 0.0311 | 2267 | 18423 | all | phecode |
| 663 |
Umbilical cord complications during labor andUmbilical cord complications during labor and delivery
|
Pregnancy Complications | 1 | 0.918 – 1.1 | 0.918 | 533 | 5319 | all | phecode |
| 665 | Obstetrical/birth trauma | Pregnancy Complications | 0.979 | 0.95 – 1.01 | 0.171 | 5314 | 29494 | all | phecode |
| 669 | Complications of labor and delivery NEC | Pregnancy Complications | 0.991 | 0.95 – 1.03 | 0.655 | 2554 | 21200 | all | phecode |
| 671 |
Venous/cerebrovascular complications embolismVenous/cerebrovascular complications embolism in pregnancy and the puerperium
|
Pregnancy Complications | 0.962 | 0.817 – 1.13 | 0.639 | 164 | 1630 | all | phecode |
| 674 | Other complications of the puerperium NEC | Pregnancy Complications | 0.887 | 0.778 – 1.01 | 0.0681 | 262 | 2609 | all | phecode |
| 676 |
Other disorders of the breast associated withOther disorders of the breast associated with childbirth and disorders of lactation
|
Pregnancy Complications | 0.97 | 0.745 – 1.26 | 0.819 | 63 | 624 | all | phecode |
| 679 | Complications of in utero procedures | Dermatologic | 1.31 | 0.986 – 1.74 | 0.0585 | 53 | 530 | all | phecode |
| 681 | Superficial cellulitis and abscess | Dermatologic | 1.03 | 1 – 1.05 | 0.0423 | 7421 | 74210 | all | phecode |
| 681.1 | Cellulitis and abscess of fingers/toes | Dermatologic | 1.05 | 0.964 – 1.15 | 0.255 | 566 | 5660 | all | phecode |
| 681.2 | Cellulitis and abscess of face/neck | Dermatologic | 1.04 | 0.953 – 1.14 | 0.349 | 522 | 5220 | all | phecode |
| 681.3 | Cellulitis and abscess of arm/hand | Dermatologic | 1.02 | 0.995 – 1.05 | 0.11 | 5514 | 55140 | all | phecode |
| 681.5 | Cellulitis and abscess of leg, except foot | Dermatologic | 1.02 | 0.996 – 1.05 | 0.0943 | 5521 | 55210 | all | phecode |
| 681.6 | Cellulitis and abscess of foot, toe | Dermatologic | 1.02 | 0.997 – 1.05 | 0.0853 | 5477 | 54770 | all | phecode |
| 681.7 | Cellulitis and abscess of trunk | Dermatologic | 1.06 | 0.973 – 1.15 | 0.183 | 600 | 6000 | all | phecode |
| 686 |
Other local infections of skin and subcutaneousOther local infections of skin and subcutaneous tissue
|
Dermatologic | 1.09 | 1.03 – 1.15 | 0.00358 | 1348 | 13480 | all | phecode |
| 686.1 | Carbuncle and furuncle | Dermatologic | 1.22 | 0.983 – 1.52 | 0.0664 | 87 | 870 | all | phecode |
| 687 | Symptoms affecting skin | Dermatologic | 1.04 | 0.953 – 1.13 | 0.395 | 604 | 6040 | all | phecode |
| 687.2 | Localized superficial swelling, mass, or lump | Dermatologic | 0.953 | 0.842 – 1.08 | 0.446 | 284 | 2840 | all | phecode |
| 687.3 | Changes in skin texture | Dermatologic | 1.09 | 0.894 – 1.33 | 0.382 | 108 | 1080 | all | phecode |
| 689 | Disorder of skin and subcutaneous tissue NOS | Dermatologic | 1.07 | 1.04 – 1.1 | 1.45e-06 | 5765 | 57650 | all | phecode |
| 690 | Erythematosquamous dermatosis | Dermatologic | 1.13 | 0.888 – 1.43 | 0.307 | 72 | 720 | all | phecode |
| 690.1 | Seborrheic dermatitis | Dermatologic | 1.14 | 0.855 – 1.5 | 0.364 | 53 | 530 | all | phecode |
| 691 | Congenital anomalies of skin | Dermatologic | 1.21 | 1 – 1.45 | 0.0457 | 120 | 1200 | all | phecode |
| 694 | Dyschromia and Vitiligo | Dermatologic | 1.09 | 1.02 – 1.17 | 0.00854 | 987 | 9864 | all | phecode |
| 694.1 | Vitiligo | Dermatologic | 0.911 | 0.693 – 1.19 | 0.492 | 60 | 600 | all | phecode |
| 694.2 | Other dyschromia | Dermatologic | 1.1 | 1.03 – 1.19 | 0.00772 | 783 | 7830 | all | phecode |
| 694.3 | Vascular disorders of skin | Dermatologic | 1.17 | 0.966 – 1.41 | 0.104 | 117 | 1164 | all | phecode |
| 695 | Erythematous conditions | Dermatologic | 1.03 | 0.986 – 1.07 | 0.187 | 2416 | 24160 | all | phecode |
| 695.1 | Toxic erythema | Dermatologic | 0.998 | 0.815 – 1.22 | 0.985 | 109 | 1090 | all | phecode |
| 695.2 | Bullous dermatoses | Dermatologic | 0.97 | 0.813 – 1.16 | 0.736 | 141 | 1410 | all | phecode |
| 695.21 | Dermatitis herpetiformis | Dermatologic | 0.91 | 0.685 – 1.2 | 0.501 | 57 | 570 | all | phecode |
| 695.22 | Pemphigus and pemphigoid | Dermatologic | 1.04 | 0.814 – 1.31 | 0.766 | 75 | 750 | all | phecode |
| 695.3 | Rosacea | Dermatologic | 1.05 | 0.936 – 1.18 | 0.384 | 310 | 3100 | all | phecode |
| 695.4 | Lupus (localized and systemic) | Dermatologic | 1.03 | 0.928 – 1.14 | 0.601 | 418 | 4180 | all | phecode |
| 695.41 | Cutaneous lupus erythematosus | Dermatologic | 1.19 | 0.995 – 1.42 | 0.054 | 130 | 1300 | all | phecode |
| 695.42 | Systemic lupus erythematosus | Dermatologic | 0.96 | 0.857 – 1.07 | 0.476 | 342 | 3420 | all | phecode |
| 695.7 | Prurigo and Lichen | Dermatologic | 1.02 | 0.945 – 1.1 | 0.629 | 777 | 7770 | all | phecode |
| 695.8 | Other specified erythematous conditions | Dermatologic | 1.09 | 0.959 – 1.25 | 0.175 | 242 | 2420 | all | phecode |
| 695.81 | Erythema nodosum | Dermatologic | 1.03 | 0.811 – 1.3 | 0.807 | 76 | 760 | all | phecode |
| 695.9 | Unspecified erythematous condition | Dermatologic | 1.04 | 0.949 – 1.15 | 0.368 | 468 | 4680 | all | phecode |
| 696 | Psoriasis and related disorders | Dermatologic | 0.986 | 0.944 – 1.03 | 0.539 | 2290 | 22900 | all | phecode |
| 696.4 | Psoriasis | Dermatologic | 0.989 | 0.946 – 1.03 | 0.617 | 2234 | 22340 | all | phecode |
| 696.41 | Psoriasis vulgaris | Dermatologic | 1 | 0.955 – 1.06 | 0.863 | 1681 | 16810 | all | phecode |
| 696.42 | Psoriatic arthropathy | Dermatologic | 0.953 | 0.881 – 1.03 | 0.233 | 708 | 7080 | all | phecode |
| 697 | Sarcoidosis | Dermatologic | 0.953 | 0.871 – 1.04 | 0.287 | 549 | 5480 | all | phecode |
| 698 | Pruritus and related conditions | Dermatologic | 1.02 | 0.948 – 1.1 | 0.582 | 783 | 7830 | all | phecode |
| 700 | Corns and callosities | Dermatologic | 1.01 | 0.895 – 1.14 | 0.858 | 293 | 2930 | all | phecode |
| 701 |
Other hypertrophic and atrophic conditions ofOther hypertrophic and atrophic conditions of skin
|
Dermatologic | 1.08 | 1.05 – 1.11 | 7.28e-07 | 4782 | 47820 | all | phecode |
| 701.1 | Keratoderma, acquired | Dermatologic | 0.983 | 0.784 – 1.23 | 0.883 | 86 | 860 | all | phecode |
| 701.2 | Scar conditions and fibrosis of skin | Dermatologic | 1.1 | 1.06 – 1.15 | 4.01e-06 | 2350 | 23500 | all | phecode |
| 701.3 | Circumscribed scleroderma | Dermatologic | 0.944 | 0.718 – 1.23 | 0.671 | 59 | 590 | all | phecode |
| 701.4 | Keloid scar | Dermatologic | 1.07 | 0.934 – 1.24 | 0.31 | 216 | 2160 | all | phecode |
| 701.5 | Abnormal granulation tissue | Dermatologic | 1.03 | 0.935 – 1.14 | 0.535 | 454 | 4540 | all | phecode |
| 701.6 | Acquired acanthosis nigricans | Dermatologic | 1.16 | 0.95 – 1.42 | 0.135 | 102 | 1020 | all | phecode |
| 702 |
Degenerative skin conditions and otherDegenerative skin conditions and other dermatoses
|
Dermatologic | 1.14 | 1.11 – 1.17 | 8e-21 | 5492 | 54920 | all | phecode |
| 702.1 | Actinic keratosis | Dermatologic | 1.27 | 1.22 – 1.32 | 6.42e-32 | 2581 | 25810 | all | phecode |
| 702.2 | Seborrheic keratosis | Dermatologic | 1.05 | 1.01 – 1.09 | 0.00799 | 3075 | 30750 | all | phecode |
| 703 | Diseases of nail, NOS | Dermatologic | 1.01 | 0.907 – 1.13 | 0.823 | 355 | 3546 | all | phecode |
| 704 | Diseases of hair and hair follicles | Dermatologic | 1.06 | 1.03 – 1.09 | 7.23e-05 | 5287 | 52864 | all | phecode |
| 704.1 | Alopecia | Dermatologic | 0.907 | 0.75 – 1.09 | 0.3 | 127 | 1270 | all | phecode |
| 704.8 |
Other specified diseases of hair and hairOther specified diseases of hair and hair follicles
|
Dermatologic | 1.14 | 0.904 – 1.45 | 0.252 | 76 | 760 | all | phecode |
| 705 | Disorders of sweat glands | Dermatologic | 0.966 | 0.84 – 1.11 | 0.621 | 229 | 2289 | all | phecode |
| 705.3 | Hidradenitis | Dermatologic | 0.973 | 0.834 – 1.13 | 0.725 | 187 | 1869 | all | phecode |
| 706 | Diseases of sebaceous glands | Dermatologic | 1.07 | 1.04 – 1.09 | 7.09e-09 | 8876 | 88734 | all | phecode |
| 706.1 | Acne | Dermatologic | 0.89 | 0.701 – 1.13 | 0.329 | 78 | 780 | all | phecode |
| 706.2 | Sebaceous cyst | Dermatologic | 1.07 | 1.04 – 1.09 | 4.45e-09 | 8804 | 88014 | all | phecode |
| 707 | Chronic ulcer of skin | Dermatologic | 1.03 | 0.981 – 1.08 | 0.249 | 1990 | 19900 | all | phecode |
| 707.1 | Decubitus ulcer | Dermatologic | 1.04 | 0.972 – 1.11 | 0.249 | 913 | 9130 | all | phecode |
| 709 | Diffuse diseases of connective tissue | Dermatologic | 0.964 | 0.93 – 0.999 | 0.0427 | 3451 | 34510 | all | phecode |
| 709.2 | Sicca syndrome | Dermatologic | 0.943 | 0.859 – 1.04 | 0.22 | 504 | 5040 | all | phecode |
| 709.3 | Systemic sclerosis | Dermatologic | 1.01 | 0.863 – 1.18 | 0.892 | 174 | 1740 | all | phecode |
| 709.6 |
Other specified diffuse diseases of connectiveOther specified diffuse diseases of connective tissue
|
Dermatologic | 0.973 | 0.75 – 1.26 | 0.834 | 65 | 650 | all | phecode |
| 709.7 | Unspecified diffuse connective tissue disease | Dermatologic | 0.965 | 0.927 – 1 | 0.0779 | 2721 | 27210 | all | phecode |
| 710 |
Osteomyelitis, periostitis, and otherOsteomyelitis, periostitis, and other infections involving bone
|
Musculoskeletal | 1.02 | 0.941 – 1.11 | 0.581 | 613 | 6130 | all | phecode |
| 710.1 | Osteomyelitis | Musculoskeletal | 1.03 | 0.941 – 1.12 | 0.551 | 566 | 5660 | all | phecode |
| 710.12 | Chronic osteomyelitis | Musculoskeletal | 1.04 | 0.899 – 1.21 | 0.565 | 196 | 1960 | all | phecode |
| 710.19 | Unspecified osteomyelitis | Musculoskeletal | 1.01 | 0.909 – 1.12 | 0.875 | 402 | 4020 | all | phecode |
| 711 | Arthropathy associated with infections | Musculoskeletal | 1.04 | 0.938 – 1.15 | 0.475 | 429 | 4290 | all | phecode |
| 711.1 | Pyogenic arthritis | Musculoskeletal | 1.08 | 0.962 – 1.21 | 0.191 | 330 | 3300 | all | phecode |
| 712 | Infective connective tissue disorders | Musculoskeletal | 1.12 | 0.892 – 1.4 | 0.324 | 82 | 820 | all | phecode |
| 713 |
Arthropathy associated with other disordersArthropathy associated with other disorders classified elsewhere
|
Musculoskeletal | 0.994 | 0.839 – 1.18 | 0.946 | 151 | 1510 | all | phecode |
| 713.5 |
Arthropathy associated with neurologicalArthropathy associated with neurological disorders
|
Musculoskeletal | 0.937 | 0.723 – 1.2 | 0.611 | 68 | 680 | all | phecode |
| 714 |
Rheumatoid arthritis and other inflammatoryRheumatoid arthritis and other inflammatory polyarthropathies
|
Musculoskeletal | 1.03 | 1 – 1.06 | 0.0446 | 4858 | 48575 | all | phecode |
| 714.1 | Rheumatoid arthritis | Musculoskeletal | 1.04 | 1 – 1.07 | 0.029 | 4394 | 43935 | all | phecode |
| 715 | Other inflammatory spondylopathies | Musculoskeletal | 1.03 | 0.983 – 1.09 | 0.188 | 1670 | 16700 | all | phecode |
| 715.1 | Sacroiliitis NEC | Musculoskeletal | 1.32 | 1.09 – 1.6 | 0.0041 | 113 | 1130 | all | phecode |
| 715.2 | Ankylosing spondylitis | Musculoskeletal | 0.99 | 0.911 – 1.08 | 0.814 | 619 | 6190 | all | phecode |
| 716 | Other arthropathies | Musculoskeletal | 1.01 | 0.996 – 1.02 | 0.203 | 37608 | 265965 | all | phecode |
| 716.1 | Unspecified polyarthropathy or polyarthritis | Musculoskeletal | 1.06 | 1.03 – 1.1 | 0.000706 | 3517 | 35170 | all | phecode |
| 716.2 | Unspecified monoarthritis | Musculoskeletal | 1.01 | 0.995 – 1.03 | 0.176 | 15561 | 155610 | all | phecode |
| 716.9 | Arthropathy NOS | Musculoskeletal | 1.01 | 0.995 – 1.02 | 0.272 | 35982 | 254727 | all | phecode |
| 717 | Polymyalgia Rheumatica | Musculoskeletal | 1.02 | 0.961 – 1.09 | 0.495 | 1152 | 11520 | all | phecode |
| 720 | Spinal stenosis | Musculoskeletal | 1.01 | 0.973 – 1.04 | 0.714 | 3715 | 37150 | all | phecode |
| 721 | Spondylosis and allied disorders | Musculoskeletal | 1.03 | 1.01 – 1.05 | 0.0158 | 7872 | 78720 | all | phecode |
| 721.1 | Spondylosis without myelopathy | Musculoskeletal | 1.02 | 0.991 – 1.05 | 0.183 | 5042 | 50420 | all | phecode |
| 721.2 | Spondylosis with myelopathy | Musculoskeletal | 1.08 | 0.933 – 1.26 | 0.286 | 189 | 1890 | all | phecode |
| 721.8 | Other allied disorders of spine | Musculoskeletal | 1.09 | 0.976 – 1.21 | 0.126 | 351 | 3510 | all | phecode |
| 722 | Intervertebral disc disorders | Musculoskeletal | 1.01 | 0.986 – 1.03 | 0.482 | 9170 | 91700 | all | phecode |
| 722.1 | Displacement of intervertebral disc | Musculoskeletal | 1.1 | 1 – 1.2 | 0.0421 | 508 | 5080 | all | phecode |
| 722.6 | Degeneration of intervertebral disc | Musculoskeletal | 1.01 | 0.974 – 1.05 | 0.532 | 2826 | 28260 | all | phecode |
| 722.8 | Postlaminectomy syndrome | Musculoskeletal | 1.02 | 0.792 – 1.32 | 0.864 | 67 | 670 | all | phecode |
| 722.9 | Other and unspecified disc disorder | Musculoskeletal | 0.994 | 0.964 – 1.03 | 0.721 | 4398 | 43980 | all | phecode |
| 723 | Other disorders of cervical region | Musculoskeletal | 0.953 | 0.87 – 1.04 | 0.3 | 521 | 5210 | all | phecode |
| 723.1 | Torticollis | Musculoskeletal | 0.968 | 0.791 – 1.18 | 0.75 | 107 | 1070 | all | phecode |
| 724 | Other and unspecified disorders of back | Musculoskeletal | 1.01 | 0.961 – 1.05 | 0.804 | 2076 | 20760 | all | phecode |
| 724.1 | Disorders of sacrum | Musculoskeletal | 0.941 | 0.847 – 1.04 | 0.25 | 404 | 4040 | all | phecode |
| 724.2 | Disorders of coccyx | Musculoskeletal | 0.929 | 0.836 – 1.03 | 0.161 | 407 | 4070 | all | phecode |
| 724.8 | Other symptoms referable to back | Musculoskeletal | 1.05 | 0.806 – 1.36 | 0.722 | 63 | 630 | all | phecode |
| 724.9 | Other unspecified back disorders | Musculoskeletal | 1.02 | 0.97 – 1.08 | 0.423 | 1616 | 16160 | all | phecode |
| 726 | Peripheral enthesopathies and allied syndromes | Musculoskeletal | 0.996 | 0.979 – 1.01 | 0.643 | 14821 | 148210 | all | phecode |
| 726.1 | Enthesopathy | Musculoskeletal | 1 | 0.981 – 1.02 | 0.842 | 9557 | 95570 | all | phecode |
| 726.2 | Synoviopathy | Musculoskeletal | 0.944 | 0.841 – 1.06 | 0.328 | 330 | 3300 | all | phecode |
| 726.3 | Bursitis | Musculoskeletal | 0.931 | 0.867 – 1 | 0.0506 | 856 | 8560 | all | phecode |
| 727 | Other disorders of synovium, tendon, and bursa | Musculoskeletal | 1.01 | 0.983 – 1.03 | 0.592 | 7593 | 75930 | all | phecode |
| 727.1 | Synovitis and tenosynovitis | Musculoskeletal | 1.02 | 0.976 – 1.06 | 0.459 | 2738 | 27380 | all | phecode |
| 727.2 | Bursitis disorders | Musculoskeletal | 1.09 | 0.891 – 1.33 | 0.395 | 106 | 1060 | all | phecode |
| 727.4 | Ganglion and cyst of synovium, tendon, and bursa | Musculoskeletal | 0.984 | 0.948 – 1.02 | 0.389 | 3175 | 31750 | all | phecode |
| 727.5 | Rupture of synovium | Musculoskeletal | 1.03 | 0.945 – 1.12 | 0.5 | 587 | 5870 | all | phecode |
| 727.6 | Rupture of tendon, nontraumatic | Musculoskeletal | 1 | 0.896 – 1.12 | 0.992 | 352 | 3520 | all | phecode |
| 727.7 | Contracture of tendon (sheath) | Musculoskeletal | 1 | 0.841 – 1.19 | 0.97 | 142 | 1420 | all | phecode |
| 728 | Disorders of muscle, ligament, and fascia | Musculoskeletal | 1.01 | 0.98 – 1.05 | 0.44 | 3697 | 36970 | all | phecode |
| 728.7 | Fasciitis | Musculoskeletal | 1.02 | 0.986 – 1.06 | 0.248 | 3482 | 34820 | all | phecode |
| 728.71 |
Contracture of palmar fascia [Dupuytren'sContracture of palmar fascia [Dupuytren's disease]
|
Musculoskeletal | 1.02 | 0.986 – 1.06 | 0.248 | 3482 | 34820 | all | phecode |
| 729 | Other disorders of soft tissues | Musculoskeletal | 0.977 | 0.951 – 1 | 0.0892 | 6051 | 60510 | all | phecode |
| 729.1 | Rheumatism, unspecified and fibrositis | Musculoskeletal | 1.02 | 0.958 – 1.09 | 0.503 | 1004 | 10040 | all | phecode |
| 731 |
Osteitis deformans and osteopathies associatedOsteitis deformans and osteopathies associated with other disorders classified elsewhere
|
Musculoskeletal | 0.897 | 0.79 – 1.02 | 0.0931 | 277 | 2770 | all | phecode |
| 731.1 | Osteitis deformans [Paget's disease of bone] | Musculoskeletal | 0.907 | 0.795 – 1.03 | 0.14 | 262 | 2620 | all | phecode |
| 732 | Osteochondropathies | Musculoskeletal | 0.908 | 0.824 – 1 | 0.0497 | 472 | 4720 | all | phecode |
| 732.1 | Juvenile osteochondrosis | Musculoskeletal | 0.876 | 0.755 – 1.01 | 0.0777 | 207 | 2070 | all | phecode |
| 732.7 | Osteochondritis dissecans | Musculoskeletal | 0.998 | 0.761 – 1.31 | 0.989 | 59 | 590 | all | phecode |
| 733 | Other disorders of bone and cartilage | Musculoskeletal | 1.02 | 0.975 – 1.07 | 0.348 | 1792 | 17920 | all | phecode |
| 733.2 | Cyst of bone | Musculoskeletal | 1.07 | 0.951 – 1.2 | 0.267 | 319 | 3190 | all | phecode |
| 735 | Acquired foot deformities | Musculoskeletal | 1.01 | 0.991 – 1.03 | 0.251 | 9764 | 97640 | all | phecode |
| 735.1 | Flat foot | Musculoskeletal | 1.11 | 0.956 – 1.29 | 0.166 | 190 | 1900 | all | phecode |
| 735.2 | Acquired toe deformities | Musculoskeletal | 1.02 | 0.995 – 1.05 | 0.101 | 5091 | 50910 | all | phecode |
| 735.21 | Hammer toe (acquired) | Musculoskeletal | 1.02 | 0.97 – 1.07 | 0.494 | 1914 | 19140 | all | phecode |
| 735.23 | Hallux rigidus | Musculoskeletal | 1.03 | 0.978 – 1.09 | 0.252 | 1548 | 15480 | all | phecode |
| 735.3 | Hallux valgus (Bunion) | Musculoskeletal | 1 | 0.979 – 1.03 | 0.741 | 6639 | 66390 | all | phecode |
| 736 | Other acquired deformities of limbs | Musculoskeletal | 0.973 | 0.924 – 1.02 | 0.289 | 1644 | 16440 | all | phecode |
| 736.2 | Acquired deformities of finger | Musculoskeletal | 1.04 | 0.91 – 1.18 | 0.571 | 248 | 2480 | all | phecode |
| 737 | Curvature of spine | Musculoskeletal | 1.04 | 0.974 – 1.1 | 0.266 | 1135 | 11350 | all | phecode |
| 737.3 | Kyphoscoliosis and scoliosis | Musculoskeletal | 1.02 | 0.962 – 1.09 | 0.45 | 1064 | 10640 | all | phecode |
| 738 | Other acquired musculoskeletal deformity | Musculoskeletal | 1.02 | 0.97 – 1.07 | 0.498 | 1921 | 19210 | all | phecode |
| 738.4 | Acquired spondylolisthesis | Musculoskeletal | 1.01 | 0.96 – 1.07 | 0.648 | 1520 | 15200 | all | phecode |
| 739 | Contracture of joint | Musculoskeletal | 1.12 | 1.02 – 1.23 | 0.0191 | 489 | 4890 | all | phecode |
| 740 | Osteoarthrosis | Musculoskeletal | 1.01 | 0.995 – 1.02 | 0.213 | 27860 | 232406 | all | phecode |
| 740.1 | Osteoarthritis; localized | Musculoskeletal | 1.01 | 0.993 – 1.02 | 0.286 | 17461 | 169819 | all | phecode |
| 740.11 | Osteoarthrosis, localized, primary | Musculoskeletal | 1.02 | 0.999 – 1.04 | 0.0658 | 8997 | 89952 | all | phecode |
| 740.12 | Osteoarthrosis, localized, secondary | Musculoskeletal | 1.09 | 0.976 – 1.22 | 0.124 | 348 | 3480 | all | phecode |
| 740.2 | Osteoarthrosis, generalized | Musculoskeletal | 1.14 | 1.05 – 1.24 | 0.0016 | 599 | 5990 | all | phecode |
| 740.9 | Osteoarthrosis NOS | Musculoskeletal | 1.02 | 0.998 – 1.04 | 0.0878 | 12302 | 123014 | all | phecode |
| 741 | Symptoms and disorders of the joints | Musculoskeletal | 1.02 | 0.981 – 1.05 | 0.384 | 3624 | 36240 | all | phecode |
| 741.1 | Ankylosis of joint | Musculoskeletal | 1.06 | 0.866 – 1.3 | 0.555 | 102 | 1020 | all | phecode |
| 741.2 | Stiffness of joint | Musculoskeletal | 0.997 | 0.916 – 1.08 | 0.947 | 614 | 6140 | all | phecode |
| 741.3 | Difficulty in walking | Musculoskeletal | 0.978 | 0.826 – 1.15 | 0.788 | 155 | 1550 | all | phecode |
| 741.4 | Joint effusions | Musculoskeletal | 1.04 | 0.988 – 1.1 | 0.123 | 1420 | 14200 | all | phecode |
| 741.5 | Hemarthrosis | Musculoskeletal | 0.912 | 0.748 – 1.11 | 0.353 | 111 | 1110 | all | phecode |
| 741.6 | Villonodular synovitis | Musculoskeletal | 0.815 | 0.603 – 1.09 | 0.165 | 54 | 540 | all | phecode |
| 742 | Derangement of joint, non-traumatic | Musculoskeletal | 1.01 | 0.973 – 1.05 | 0.585 | 2906 | 29060 | all | phecode |
| 742.1 | Loose body in joint | Musculoskeletal | 0.956 | 0.852 – 1.07 | 0.439 | 332 | 3320 | all | phecode |
| 742.2 |
Pathological, developmental or recurrentPathological, developmental or recurrent dislocation
|
Musculoskeletal | 0.89 | 0.719 – 1.1 | 0.276 | 96 | 960 | all | phecode |
| 742.8 | Articular cartilage disorder | Musculoskeletal | 1.01 | 0.921 – 1.11 | 0.814 | 499 | 4990 | all | phecode |
| 742.9 | Other derangement of joint | Musculoskeletal | 1.02 | 0.971 – 1.07 | 0.479 | 1995 | 19950 | all | phecode |
| 743 |
Osteoporosis, osteopenia and pathologicalOsteoporosis, osteopenia and pathological fracture
|
Musculoskeletal | 1.01 | 0.985 – 1.03 | 0.45 | 7628 | 76256 | all | phecode |
| 743.1 | Osteoporosis | Musculoskeletal | 1.01 | 0.98 – 1.03 | 0.67 | 6434 | 64335 | all | phecode |
| 743.11 | Osteoporosis NOS | Musculoskeletal | 0.997 | 0.97 – 1.02 | 0.828 | 5577 | 55767 | all | phecode |
| 743.13 | Other specified osteoporosis | Musculoskeletal | 1.05 | 0.956 – 1.14 | 0.326 | 530 | 5299 | all | phecode |
| 743.2 | Pathologic fracture | Musculoskeletal | 1.05 | 0.96 – 1.15 | 0.275 | 523 | 5230 | all | phecode |
| 743.9 |
Osteopenia or other disorder of bone andOsteopenia or other disorder of bone and cartilage
|
Musculoskeletal | 1.01 | 0.938 – 1.08 | 0.818 | 819 | 8190 | all | phecode |
| 745 | Pain in joint | Musculoskeletal | 1.03 | 1 – 1.05 | 0.0361 | 7994 | 79930 | all | phecode |
| 747 | Cardiac and circulatory congenital anomalies | Congenital Anomalies | 0.987 | 0.949 – 1.03 | 0.514 | 2822 | 28217 | all | phecode |
| 747.1 | Cardiac congenital anomalies | Congenital Anomalies | 0.984 | 0.945 – 1.02 | 0.425 | 2645 | 26447 | all | phecode |
| 747.11 | Cardiac shunt/ heart septal defect | Congenital Anomalies | 0.992 | 0.911 – 1.08 | 0.862 | 587 | 5870 | all | phecode |
| 747.12 | Valvular heart disease/ heart chambers | Congenital Anomalies | 1.06 | 0.925 – 1.21 | 0.406 | 236 | 2360 | all | phecode |
| 747.13 | Congenital anomalies of great vessels | Congenital Anomalies | 0.97 | 0.924 – 1.02 | 0.218 | 1823 | 18227 | all | phecode |
| 747.2 |
Congenital anomalies of peripheral vascularCongenital anomalies of peripheral vascular system
|
Congenital Anomalies | 1.01 | 0.861 – 1.19 | 0.883 | 167 | 1670 | all | phecode |
| 748 | Anomalies of respiratory system, congenital | Congenital Anomalies | 0.984 | 0.736 – 1.31 | 0.913 | 51 | 510 | all | phecode |
| 749 | Congenital anomalies of face and neck | Congenital Anomalies | 1.03 | 0.919 – 1.16 | 0.59 | 324 | 3240 | all | phecode |
| 750 | Digestive congenital anomalies | Congenital Anomalies | 1.06 | 0.977 – 1.14 | 0.17 | 704 | 7040 | all | phecode |
| 750.1 | Upper gastrointestinal congenital anomalies | Congenital Anomalies | 0.99 | 0.883 – 1.11 | 0.864 | 336 | 3360 | all | phecode |
| 750.13 | Congenital anomalies of mouth/tongue | Congenital Anomalies | 0.94 | 0.807 – 1.09 | 0.419 | 193 | 1930 | all | phecode |
| 750.2 | Lower gastrointestinal congenital anomalies | Congenital Anomalies | 1.12 | 1.01 – 1.25 | 0.0346 | 364 | 3640 | all | phecode |
| 750.21 | Congenital anomalies of intestine | Congenital Anomalies | 1.1 | 0.957 – 1.26 | 0.179 | 229 | 2290 | all | phecode |
| 750.22 |
Congenital anomaly of gallbladder, bile ductsCongenital anomaly of gallbladder, bile ducts, liver, pancreas
|
Congenital Anomalies | 1.19 | 0.987 – 1.44 | 0.0646 | 118 | 1180 | all | phecode |
| 751 | Genitourinary congenital anomalies | Congenital Anomalies | 0.997 | 0.946 – 1.05 | 0.9 | 1590 | 15900 | all | phecode |
| 751.1 | Congenital anomalies of genital organs | Congenital Anomalies | 0.97 | 0.898 – 1.05 | 0.434 | 731 | 7310 | all | phecode |
| 751.11 | Congenital anomalies of female genital organs | Congenital Anomalies | 1 | 0.908 – 1.1 | 0.989 | 457 | 4570 | all | phecode |
| 751.12 | Congenital anomalies of male genital organs | Congenital Anomalies | 0.965 | 0.84 – 1.11 | 0.612 | 228 | 2280 | all | phecode |
| 751.2 | Congenital anomalies of urinary system | Congenital Anomalies | 1.01 | 0.941 – 1.08 | 0.769 | 850 | 8500 | all | phecode |
| 751.21 | Cystic kidney disease | Congenital Anomalies | 1.01 | 0.913 – 1.12 | 0.837 | 426 | 4260 | all | phecode |
| 751.22 | Other specified congenital anomalies of kidney | Congenital Anomalies | 0.981 | 0.876 – 1.1 | 0.74 | 339 | 3390 | all | phecode |
| 752 | Nervous system congenital anomalies | Congenital Anomalies | 1.02 | 0.913 – 1.14 | 0.699 | 336 | 3360 | all | phecode |
| 752.1 | Neural tube defects | Congenital Anomalies | 1.03 | 0.904 – 1.17 | 0.665 | 257 | 2570 | all | phecode |
| 752.11 | Spina bifida | Congenital Anomalies | 1.1 | 0.955 – 1.27 | 0.18 | 211 | 2110 | all | phecode |
| 752.2 |
Other specified congenital anomalies of nervousOther specified congenital anomalies of nervous system
|
Congenital Anomalies | 1.04 | 0.822 – 1.3 | 0.763 | 80 | 800 | all | phecode |
| 753 | Congenital anomalies of the eye | Congenital Anomalies | 0.848 | 0.703 – 1.02 | 0.0783 | 131 | 1310 | all | phecode |
| 753.1 | Congenital cataract and lens anomalies | Congenital Anomalies | 0.975 | 0.767 – 1.23 | 0.834 | 76 | 760 | all | phecode |
| 754 | Congenital musculoskeletal deformities of spine | Congenital Anomalies | 1.03 | 0.846 – 1.25 | 0.759 | 110 | 1100 | all | phecode |
| 755 | Congenital anomalies of limbs | Congenital Anomalies | 0.992 | 0.899 – 1.09 | 0.873 | 449 | 4490 | all | phecode |
| 755.1 | Congenital deformities of feet | Congenital Anomalies | 1.03 | 0.89 – 1.18 | 0.713 | 210 | 2100 | all | phecode |
| 755.6 |
Other congenital anomalies of lower limbOther congenital anomalies of lower limb, including pelvic girdle
|
Congenital Anomalies | 0.968 | 0.822 – 1.14 | 0.695 | 162 | 1620 | all | phecode |
| 755.61 | Congenital hip dysplasia and deformity | Congenital Anomalies | 0.896 | 0.73 – 1.09 | 0.281 | 107 | 1070 | all | phecode |
| 756 | Other congenital musculoskeletal anomalies | Congenital Anomalies | 1.03 | 0.944 – 1.12 | 0.525 | 593 | 5930 | all | phecode |
| 756.3 |
Congenital anomalies of muscle, tendon, fasciaCongenital anomalies of muscle, tendon, fascia, and connective tissue
|
Congenital Anomalies | 1.04 | 0.829 – 1.31 | 0.709 | 81 | 810 | all | phecode |
| 756.5 | Congenital osteodystrophies | Congenital Anomalies | 1 | 0.909 – 1.11 | 0.927 | 436 | 4360 | all | phecode |
| 758 | Chromosomal anomalies and genetic disorders | Congenital Anomalies | 1.09 | 0.94 – 1.27 | 0.247 | 189 | 1890 | all | phecode |
| 758.1 | Chromosomal anomalies | Congenital Anomalies | 1.12 | 0.914 – 1.38 | 0.262 | 100 | 1000 | all | phecode |
| 759 | Other and unspecified congenital anomalies | Congenital Anomalies | 1.04 | 0.905 – 1.19 | 0.593 | 233 | 2330 | all | phecode |
| 759.1 | Anomalies of endocrine glands, congenital | Congenital Anomalies | 0.884 | 0.719 – 1.08 | 0.233 | 105 | 1050 | all | phecode |
| 760 | Back pain | Symptoms | 1.01 | 0.995 – 1.04 | 0.138 | 11163 | 111617 | all | phecode |
| 761 | Cervicalgia | Symptoms | 1.02 | 0.972 – 1.07 | 0.414 | 1792 | 17920 | all | phecode |
| 764 | Sciatica | Symptoms | 0.97 | 0.929 – 1.01 | 0.163 | 2378 | 23780 | all | phecode |
| 766 | Neuralgia, neuritis, and radiculitis NOS | Symptoms | 0.957 | 0.901 – 1.02 | 0.158 | 1182 | 11820 | all | phecode |
| 770 | Myalgia and myositis unspecified | Symptoms | 1.01 | 0.934 – 1.1 | 0.738 | 642 | 6420 | all | phecode |
| 771 | Musculoskeletal symptoms referable to limbs | Symptoms | 0.982 | 0.915 – 1.05 | 0.614 | 874 | 8732 | all | phecode |
| 772 | Symptoms of the muscles | Symptoms | 1.04 | 0.958 – 1.12 | 0.356 | 676 | 6760 | all | phecode |
| 773 | Pain in limb | Symptoms | 1.02 | 0.996 – 1.05 | 0.0967 | 6290 | 62896 | all | phecode |
| 780 | Hypothermia/Chills | Symptoms | 1.03 | 0.878 – 1.2 | 0.727 | 172 | 1720 | all | phecode |
| 781 |
Symptoms involving nervous and musculoskeletalSymptoms involving nervous and musculoskeletal systems
|
Symptoms | 0.969 | 0.923 – 1.02 | 0.196 | 1880 | 18800 | all | phecode |
| 783 | Fever of unknown origin | Symptoms | 1.01 | 0.973 – 1.04 | 0.735 | 3930 | 39300 | all | phecode |
| 785 | Abdominal pain | Symptoms | 1.01 | 1 – 1.02 | 0.0451 | 40170 | 302301 | all | phecode |
| 788 | Syncope and collapse | Symptoms | 1.02 | 0.997 – 1.04 | 0.0926 | 9112 | 91099 | all | phecode |
| 789 | Nausea and vomiting | Symptoms | 1.03 | 1.01 – 1.05 | 0.00413 | 11612 | 116110 | all | phecode |
| 790 | Nonspecific findings on examination of blood | Symptoms | 0.957 | 0.807 – 1.13 | 0.607 | 150 | 1500 | all | phecode |
| 791 | Gangrene | Symptoms | 0.908 | 0.83 – 0.993 | 0.0345 | 553 | 5530 | all | phecode |
| 792 |
Abnormal Papanicolaou smear of cervix andAbnormal Papanicolaou smear of cervix and cervical HPV
|
Symptoms | 1.1 | 0.891 – 1.35 | 0.37 | 98 | 966 | all | phecode |
| 793 |
Nonspecific abnormal findings on radiologicalNonspecific abnormal findings on radiological and other examination of musculoskeletal system
|
Symptoms | 0.9 | 0.749 – 1.08 | 0.251 | 134 | 1340 | all | phecode |
| 794 |
Abnormal results of other function studiesAbnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
|
Symptoms | 0.895 | 0.738 – 1.08 | 0.251 | 120 | 1200 | all | phecode |
| 797 | Shock | Symptoms | 0.85 | 0.714 – 1.01 | 0.061 | 156 | 1560 | all | phecode |
| 797.1 | Cardiogenic shock | Symptoms | 0.862 | 0.697 – 1.06 | 0.161 | 102 | 1020 | all | phecode |
| 798 | Malaise and fatigue | Symptoms | 0.999 | 0.965 – 1.04 | 0.977 | 3424 | 34226 | all | phecode |
| 798.1 | Chronic fatigue syndrome | Symptoms | 0.98 | 0.9 – 1.07 | 0.645 | 590 | 5900 | all | phecode |
| 800 | Fracture of lower limb | Injuries & Poisonings | 1.01 | 0.984 – 1.03 | 0.482 | 7230 | 72297 | all | phecode |
| 800.1 | Fracture of neck of femur | Injuries & Poisonings | 0.989 | 0.942 – 1.04 | 0.654 | 1813 | 18130 | all | phecode |
| 800.2 | Fracture of unspecified part of femur | Injuries & Poisonings | 0.952 | 0.81 – 1.12 | 0.546 | 170 | 1700 | all | phecode |
| 800.3 | Fracture of tibia and fibula | Injuries & Poisonings | 1.02 | 0.973 – 1.06 | 0.447 | 2156 | 21560 | all | phecode |
| 800.4 | Fracture of patella | Injuries & Poisonings | 0.941 | 0.872 – 1.01 | 0.114 | 766 | 7660 | all | phecode |
| 801 | Fracture of ankle and foot | Injuries & Poisonings | 1.04 | 0.998 – 1.09 | 0.0616 | 2333 | 23325 | all | phecode |
| 801.1 | Fracture of foot | Injuries & Poisonings | 1.05 | 1 – 1.11 | 0.0305 | 1838 | 18375 | all | phecode |
| 802 | Fracture of pelvis | Injuries & Poisonings | 1.02 | 0.946 – 1.1 | 0.569 | 722 | 7220 | all | phecode |
| 803 | Fracture of upper limb | Injuries & Poisonings | 1.02 | 0.998 – 1.04 | 0.0678 | 8480 | 84788 | all | phecode |
| 803.1 | Fracture of humerus | Injuries & Poisonings | 1.02 | 0.974 – 1.08 | 0.343 | 1685 | 16840 | all | phecode |
| 803.2 | Fracture of radius and ulna | Injuries & Poisonings | 1.02 | 0.995 – 1.05 | 0.102 | 5214 | 52138 | all | phecode |
| 803.3 | Fracture of clavicle or scapula | Injuries & Poisonings | 1.03 | 0.974 – 1.08 | 0.32 | 1518 | 15180 | all | phecode |
| 804 | Fracture of hand or wrist | Injuries & Poisonings | 0.955 | 0.921 – 0.99 | 0.0125 | 3349 | 33490 | all | phecode |
| 805 |
Fracture of vertebral column without mention ofFracture of vertebral column without mention of spinal cord injury
|
Injuries & Poisonings | 1.01 | 0.952 – 1.06 | 0.817 | 1359 | 13590 | all | phecode |
| 807 | Fracture of ribs | Injuries & Poisonings | 1.07 | 0.99 – 1.15 | 0.0873 | 778 | 7780 | all | phecode |
| 809 | Fracture of unspecified bones | Injuries & Poisonings | 1.04 | 0.98 – 1.1 | 0.208 | 1306 | 13060 | all | phecode |
| 817 | Concussion | Injuries & Poisonings | 1.18 | 1.04 – 1.35 | 0.0111 | 245 | 2450 | all | phecode |
| 818 | Intracranial hemorrhage (injury) | Injuries & Poisonings | 0.982 | 0.896 – 1.07 | 0.687 | 526 | 5260 | all | phecode |
| 819 |
Skull and face fracture and other intercranialSkull and face fracture and other intercranial injury
|
Injuries & Poisonings | 1.05 | 1.01 – 1.09 | 0.0192 | 2967 | 29665 | all | phecode |
| 823 | Torus fracture | Injuries & Poisonings | 1.02 | 0.966 – 1.07 | 0.544 | 1676 | 16752 | all | phecode |
| 830 | Dislocation | Injuries & Poisonings | 0.991 | 0.947 – 1.04 | 0.698 | 2092 | 20914 | all | phecode |
| 835 | Internal derangement of knee | Injuries & Poisonings | 1.01 | 0.997 – 1.03 | 0.118 | 15259 | 152537 | all | phecode |
| 836 | Traumatic arthropathy | Injuries & Poisonings | 1.01 | 0.926 – 1.11 | 0.776 | 527 | 5270 | all | phecode |
| 840 | Sprains and strains | Injuries & Poisonings | 1.02 | 0.927 – 1.12 | 0.714 | 496 | 4960 | all | phecode |
| 850 | Hemorrhage or hematoma complicating a procedure | Injuries & Poisonings | 1.05 | 1.03 – 1.08 | 0.000231 | 5327 | 53270 | all | phecode |
| 851 |
Complications of transplants and reattachedComplications of transplants and reattached limbs
|
Injuries & Poisonings | 0.945 | 0.8 – 1.11 | 0.502 | 159 | 1590 | all | phecode |
| 853 | Complication of colostomy or enterostomy | Injuries & Poisonings | 0.985 | 0.897 – 1.08 | 0.745 | 503 | 5030 | all | phecode |
| 854 |
Complications of cardiac/vascular deviceComplications of cardiac/vascular device, implant, and graft
|
Injuries & Poisonings | 1.01 | 0.962 – 1.06 | 0.686 | 1830 | 18300 | all | phecode |
| 857 |
Mechanical complication of unspecifiedMechanical complication of unspecified genitourinary device, implant, and graft
|
Injuries & Poisonings | 1.03 | 0.976 – 1.1 | 0.254 | 1246 | 12460 | all | phecode |
| 858 | Complication of internal orthopedic device | Injuries & Poisonings | 1.02 | 0.987 – 1.06 | 0.205 | 3163 | 31630 | all | phecode |
| 859 |
Complication due to other implant and internalComplication due to other implant and internal device
|
Injuries & Poisonings | 1.04 | 1 – 1.07 | 0.0527 | 3268 | 32680 | all | phecode |
| 860 | Bone marrow or stem cell transplant | Neoplasms | 0.968 | 0.765 – 1.22 | 0.781 | 80 | 800 | all | phecode |
| 870 | Open wounds of head; neck; and trunk | Injuries & Poisonings | 1.02 | 0.988 – 1.06 | 0.212 | 3836 | 38342 | all | phecode |
| 870.1 | Open wound or laceration of eye or eyelid | Injuries & Poisonings | 0.989 | 0.871 – 1.12 | 0.862 | 270 | 2700 | all | phecode |
| 870.2 | Open wound of ear | Injuries & Poisonings | 1.03 | 0.883 – 1.19 | 0.732 | 195 | 1950 | all | phecode |
| 870.3 | Other open wound of head and face | Injuries & Poisonings | 1.02 | 0.981 – 1.06 | 0.329 | 2915 | 29141 | all | phecode |
| 870.4 | Open wound of nose and sinus | Injuries & Poisonings | 1.01 | 0.882 – 1.17 | 0.835 | 220 | 2200 | all | phecode |
| 870.6 | Open wound of neck | Injuries & Poisonings | 0.968 | 0.86 – 1.09 | 0.589 | 313 | 3130 | all | phecode |
| 871 | Open wounds of extremities | Injuries & Poisonings | 0.976 | 0.945 – 1.01 | 0.139 | 4216 | 42160 | all | phecode |
| 871.1 | Open wound of hand except finger(s) | Injuries & Poisonings | 1.01 | 0.755 – 1.33 | 0.966 | 53 | 530 | all | phecode |
| 871.2 | Open wound of finger(s) | Injuries & Poisonings | 0.846 | 0.677 – 1.05 | 0.133 | 91 | 910 | all | phecode |
| 871.3 | Open wound of foot except toe(s) alone | Injuries & Poisonings | 0.984 | 0.841 – 1.15 | 0.841 | 179 | 1790 | all | phecode |
| 872 | Traumatic amputation | Injuries & Poisonings | 0.939 | 0.853 – 1.03 | 0.198 | 476 | 4760 | all | phecode |
| 873 | Broken tooth | Injuries & Poisonings | 0.983 | 0.857 – 1.13 | 0.804 | 229 | 2290 | all | phecode |
| 874 | Complication of amputation stump | Injuries & Poisonings | 1.02 | 0.87 – 1.19 | 0.804 | 172 | 1720 | all | phecode |
| 905 |
Late effects of musculoskeletal and connectiveLate effects of musculoskeletal and connective tissue injuries
|
Injuries & Poisonings | 0.957 | 0.81 – 1.13 | 0.598 | 158 | 1580 | all | phecode |
| 907 | Injuries to the nervous system | Injuries & Poisonings | 0.996 | 0.94 – 1.05 | 0.89 | 1315 | 13150 | all | phecode |
| 915 | Superficial injury without mention of infection | Injuries & Poisonings | 1.04 | 1.01 – 1.07 | 0.0176 | 4278 | 42778 | all | phecode |
| 916 | Contusion | Injuries & Poisonings | 1.04 | 0.981 – 1.09 | 0.199 | 1484 | 14840 | all | phecode |
| 930 | Allergic reaction to food | Injuries & Poisonings | 0.923 | 0.79 – 1.08 | 0.305 | 183 | 1830 | all | phecode |
| 938 | Dermatitis due to solar radiation | Injuries & Poisonings | 1.31 | 1.18 – 1.46 | 1.98e-07 | 390 | 3900 | all | phecode |
| 938.2 | Chronic dermatitis due to solar radiation | Injuries & Poisonings | 1.33 | 1.17 – 1.51 | 1.12e-05 | 253 | 2530 | all | phecode |
| 939 |
Atopic/contact dermatitis due to other orAtopic/contact dermatitis due to other or unspecified
|
Dermatologic | 1.02 | 0.972 – 1.06 | 0.475 | 2105 | 21050 | all | phecode |
| 941 | Adverse reaction to serum or vaccine | Injuries & Poisonings | 0.914 | 0.794 – 1.05 | 0.205 | 225 | 2250 | all | phecode |
| 942 | Infusion and transfusion reaction | Injuries & Poisonings | 0.918 | 0.746 – 1.12 | 0.407 | 104 | 1040 | all | phecode |
| 946 | Anaphylactic shock NOS | Injuries & Poisonings | 1.05 | 0.964 – 1.15 | 0.252 | 551 | 5510 | all | phecode |
| 947 | Urticaria | Injuries & Poisonings | 1.03 | 0.924 – 1.14 | 0.608 | 373 | 3730 | all | phecode |
| 949 | Allergies, other | Injuries & Poisonings | 1.13 | 1.02 – 1.25 | 0.0201 | 399 | 3990 | all | phecode |
| 952 |
Spinal cord injury without evidence of spinalSpinal cord injury without evidence of spinal bone injury
|
Injuries & Poisonings | 1.08 | 0.981 – 1.2 | 0.112 | 423 | 4230 | all | phecode |
| 957 | Injury to other and unspecified nerves | Injuries & Poisonings | 0.992 | 0.874 – 1.12 | 0.903 | 270 | 2700 | all | phecode |
| 958 |
Certain early complications of trauma orCertain early complications of trauma or procedure
|
Injuries & Poisonings | 0.958 | 0.872 – 1.05 | 0.364 | 497 | 4970 | all | phecode |
| 958.1 | Postoperative shock | Injuries & Poisonings | 0.998 | 0.756 – 1.32 | 0.991 | 56 | 560 | all | phecode |
| 958.2 | Traumatic and surgical subcutaneous emphysema | Injuries & Poisonings | 0.849 | 0.662 – 1.08 | 0.186 | 74 | 740 | all | phecode |
| 960 | Poisoning by antibiotics | Injuries & Poisonings | 1.01 | 0.994 – 1.02 | 0.236 | 18183 | 181830 | all | phecode |
| 960.2 | Allergy/adverse effect of penicillin | Injuries & Poisonings | 1.01 | 0.99 – 1.02 | 0.46 | 15871 | 158710 | all | phecode |
| 961 | Poisoning by other anti-infectives | Injuries & Poisonings | 1.03 | 0.929 – 1.14 | 0.598 | 420 | 4200 | all | phecode |
| 962 | Poisoning by hormones and synthetic substitutes | Injuries & Poisonings | 1.07 | 0.959 – 1.18 | 0.233 | 382 | 3820 | all | phecode |
| 962.3 |
Hormones and synthetic substitutes causingHormones and synthetic substitutes causing adverse effects in therapeutic use
|
Injuries & Poisonings | 1.07 | 0.964 – 1.19 | 0.194 | 364 | 3640 | all | phecode |
| 963 | Poisoning by primarily systemic agents | Injuries & Poisonings | 1.04 | 0.909 – 1.2 | 0.541 | 226 | 2260 | all | phecode |
| 964 |
Poisoning by agents primarily affecting bloodPoisoning by agents primarily affecting blood constituents
|
Injuries & Poisonings | 0.973 | 0.86 – 1.1 | 0.659 | 288 | 2880 | all | phecode |
| 964.1 | Anticoagulants causing adverse effects | Injuries & Poisonings | 0.996 | 0.879 – 1.13 | 0.945 | 278 | 2780 | all | phecode |
| 965 |
Poisoning by analgesics, antipyretics, andPoisoning by analgesics, antipyretics, and antirheumatics
|
Injuries & Poisonings | 0.998 | 0.972 – 1.03 | 0.9 | 6135 | 61345 | all | phecode |
| 965.1 |
Opiates and related narcotics causing adverseOpiates and related narcotics causing adverse effects in therapeutic use
|
Injuries & Poisonings | 1.06 | 0.951 – 1.17 | 0.307 | 392 | 3920 | all | phecode |
| 965.2 |
Antirheumatics causing adverse effects inAntirheumatics causing adverse effects in therapeutic use
|
Injuries & Poisonings | 1.05 | 0.956 – 1.15 | 0.302 | 477 | 4765 | all | phecode |
| 965.3 |
Salicylates causing adverse effects inSalicylates causing adverse effects in therapeutic use
|
Injuries & Poisonings | 1.07 | 0.961 – 1.18 | 0.222 | 403 | 4025 | all | phecode |
| 966 |
Poisoning by anticonvulsants andPoisoning by anticonvulsants and anti-Parkinsonism drugs
|
Injuries & Poisonings | 0.978 | 0.892 – 1.07 | 0.638 | 513 | 5130 | all | phecode |
| 967 |
Adverse effects of sedatives or other centralAdverse effects of sedatives or other central nervous system depressants and anesthetics
|
Injuries & Poisonings | 1.05 | 0.968 – 1.15 | 0.226 | 590 | 5900 | all | phecode |
| 969 | Poisoning by psychotropic agents | Injuries & Poisonings | 1.01 | 0.965 – 1.06 | 0.643 | 1960 | 19589 | all | phecode |
| 971 |
Poisoning by drugs primarily affecting thePoisoning by drugs primarily affecting the autonomic nervous system
|
Injuries & Poisonings | 0.983 | 0.845 – 1.14 | 0.819 | 192 | 1920 | all | phecode |
| 972 |
Poisoning by agents primarily affecting thePoisoning by agents primarily affecting the cardiovascular system
|
Injuries & Poisonings | 1.06 | 0.94 – 1.2 | 0.323 | 282 | 2820 | all | phecode |
| 972.6 | Antihypertensive agents causing adverse effects | Injuries & Poisonings | 1.02 | 0.817 – 1.28 | 0.831 | 85 | 850 | all | phecode |
| 973 |
Poisoning by agents primarily affecting thePoisoning by agents primarily affecting the gastrointestinal system
|
Injuries & Poisonings | 1.12 | 0.917 – 1.36 | 0.264 | 108 | 1080 | all | phecode |
| 974 |
Poisoning by water, mineral, and uric acidPoisoning by water, mineral, and uric acid metabolism drugs
|
Injuries & Poisonings | 0.937 | 0.761 – 1.15 | 0.531 | 102 | 1020 | all | phecode |
| 975 |
Poisoning by agents primarily acting on thePoisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
|
Injuries & Poisonings | 0.913 | 0.7 – 1.18 | 0.49 | 64 | 640 | all | phecode |
| 976 |
Poisoning by agents primarily affecting skin &Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
|
Injuries & Poisonings | 1.21 | 0.919 – 1.59 | 0.168 | 58 | 580 | all | phecode |
| 977 | Personal history of allergy to medicinal agents | Injuries & Poisonings | 1.09 | 0.954 – 1.25 | 0.2 | 235 | 2350 | all | phecode |
| 979 | Adverse drug events and drug allergies | Injuries & Poisonings | 1.05 | 0.971 – 1.14 | 0.217 | 699 | 6983 | all | phecode |
| 981 |
Toxic effect of (non-ethyl) alcohol andToxic effect of (non-ethyl) alcohol and petroleum and other solvents
|
Injuries & Poisonings | 0.934 | 0.805 – 1.08 | 0.361 | 201 | 2010 | all | phecode |
| 986 | Toxic effect of carbon monoxide | Injuries & Poisonings | 1.06 | 0.836 – 1.35 | 0.606 | 73 | 730 | all | phecode |
| 987 | Toxic effect of other gases, fumes, or vapors | Injuries & Poisonings | 1.31 | 1.07 – 1.59 | 0.00675 | 106 | 1060 | all | phecode |
| 988 | Toxic effect of noxious substances eaten as food | Injuries & Poisonings | 0.759 | 0.618 – 0.927 | 0.00682 | 113 | 1130 | all | phecode |
| 989 |
Toxic effect of other substances, chieflyToxic effect of other substances, chiefly nonmedicinal as to source
|
Injuries & Poisonings | 0.884 | 0.705 – 1.1 | 0.275 | 89 | 890 | all | phecode |
| 990 | Effects radiation NOS | Injuries & Poisonings | 1.03 | 0.997 – 1.07 | 0.0705 | 3122 | 31220 | all | phecode |
| 994 | Sepsis and SIRS | Injuries & Poisonings | 0.995 | 0.958 – 1.03 | 0.78 | 3036 | 30360 | all | phecode |
| 994.2 | Sepsis | Injuries & Poisonings | 0.995 | 0.958 – 1.03 | 0.78 | 3036 | 30360 | all | phecode |
| 008 | Intestinal infection | Infectious Diseases | 1.01 | 0.984 – 1.03 | 0.594 | 8932 | 89317 | exclusion | phecode |
| 008.5 | Bacterial enteritis | Infectious Diseases | 1.04 | 0.995 – 1.08 | 0.0819 | 2723 | 27227 | exclusion | phecode |
| 008.52 | Intestinal infection due to C. difficile | Infectious Diseases | 1.08 | 0.998 – 1.18 | 0.0553 | 656 | 6560 | exclusion | phecode |
| 008.6 | Viral Enteritis | Infectious Diseases | 1.02 | 0.944 – 1.09 | 0.682 | 863 | 8630 | exclusion | phecode |
| 008.7 | Intestinal infection due to protozoa | Infectious Diseases | 1.14 | 0.853 – 1.51 | 0.365 | 53 | 530 | exclusion | phecode |
| 010 | Tuberculosis | Infectious Diseases | 1.02 | 0.867 – 1.2 | 0.82 | 174 | 1740 | exclusion | phecode |
| 038 | Septicemia | Infectious Diseases | 0.999 | 0.967 – 1.03 | 0.969 | 4198 | 41980 | exclusion | phecode |
| 038.1 | Gram negative septicemia | Infectious Diseases | 1.01 | 0.937 – 1.08 | 0.837 | 853 | 8530 | exclusion | phecode |
| 038.2 | Gram positive septicemia | Infectious Diseases | 1.03 | 0.934 – 1.13 | 0.577 | 497 | 4970 | exclusion | phecode |
| 041 | Bacterial infection NOS | Infectious Diseases | 1.01 | 0.986 – 1.03 | 0.562 | 12100 | 120995 | exclusion | phecode |
| 041.1 | Staphylococcus infections | Infectious Diseases | 1.02 | 0.983 – 1.06 | 0.286 | 3131 | 31305 | exclusion | phecode |
| 041.2 | Streptococcus infection | Infectious Diseases | 0.992 | 0.941 – 1.04 | 0.752 | 1639 | 16390 | exclusion | phecode |
| 041.4 | E. coli | Infectious Diseases | 0.993 | 0.953 – 1.03 | 0.739 | 2724 | 27240 | exclusion | phecode |
| 053 | Herpes zoster | Infectious Diseases | 0.987 | 0.889 – 1.09 | 0.806 | 421 | 4210 | exclusion | phecode |
| 053.1 | Herpes zoster with nervous system complications | Infectious Diseases | 0.981 | 0.791 – 1.21 | 0.862 | 96 | 960 | exclusion | phecode |
| 054 | Herpes simplex | Infectious Diseases | 1.04 | 0.899 – 1.2 | 0.596 | 214 | 2140 | exclusion | phecode |
| 070 | Viral hepatitis | Infectious Diseases | 1.02 | 0.938 – 1.12 | 0.595 | 593 | 5930 | exclusion | phecode |
| 070.1 | Viral hepatitis A | Infectious Diseases | 1.05 | 0.815 – 1.36 | 0.683 | 69 | 690 | exclusion | phecode |
| 070.2 | Viral hepatitis B | Infectious Diseases | 1.06 | 0.876 – 1.27 | 0.565 | 134 | 1340 | exclusion | phecode |
| 070.3 | Viral hepatitis C | Infectious Diseases | 1.02 | 0.894 – 1.16 | 0.763 | 257 | 2570 | exclusion | phecode |
| 071 | Human immunodeficiency virus [HIV] disease | Infectious Diseases | 1.08 | 0.908 – 1.29 | 0.366 | 147 | 1470 | exclusion | phecode |
| 071.1 | HIV infection, symptomatic | Infectious Diseases | 1.12 | 0.917 – 1.36 | 0.262 | 117 | 1170 | exclusion | phecode |
| 078 | Viral warts & HPV | Infectious Diseases | 1.1 | 1.03 – 1.18 | 0.0038 | 1006 | 10060 | exclusion | phecode |
| 079 | Viral infection | Infectious Diseases | 0.983 | 0.944 – 1.02 | 0.398 | 2805 | 28050 | exclusion | phecode |
| 079.1 | Varicella infection | Infectious Diseases | 0.851 | 0.645 – 1.11 | 0.235 | 65 | 650 | exclusion | phecode |
| 079.2 | Infectious mononucleosis | Infectious Diseases | 1.19 | 0.925 – 1.54 | 0.163 | 69 | 690 | exclusion | phecode |
| 080 | Postoperative infection | Infectious Diseases | 1.01 | 0.979 – 1.04 | 0.522 | 4489 | 44888 | exclusion | phecode |
| 081 |
Infection/inflammation of internal prostheticInfection/inflammation of internal prosthetic device; implant; and graft
|
Infectious Diseases | 1.02 | 0.979 – 1.07 | 0.331 | 2487 | 24870 | exclusion | phecode |
| 090 |
Sexually transmitted infections (not HIV orSexually transmitted infections (not HIV or hepatitis)
|
Infectious Diseases | 1.04 | 0.81 – 1.33 | 0.76 | 73 | 730 | exclusion | phecode |
| 1000 | Burns | Injuries & Poisonings | 0.961 | 0.88 – 1.05 | 0.375 | 582 | 5813 | exclusion | phecode |
| 1001 | Foreign body injury | Injuries & Poisonings | 1.01 | 0.954 – 1.08 | 0.662 | 1231 | 12305 | exclusion | phecode |
| 1002 |
Symptoms concerning nutrition, metabolism, andSymptoms concerning nutrition, metabolism, and development
|
Injuries & Poisonings | 0.988 | 0.96 – 1.02 | 0.416 | 5493 | 54927 | exclusion | phecode |
| 1004 |
Other signs and symptoms involving emotionalOther signs and symptoms involving emotional state
|
Injuries & Poisonings | 0.997 | 0.882 – 1.13 | 0.963 | 301 | 3010 | exclusion | phecode |
| 1005 | Other symptoms | Injuries & Poisonings | 1.02 | 0.961 – 1.07 | 0.568 | 1449 | 14484 | exclusion | phecode |
| 1006 | Crushing injury | Injuries & Poisonings | 0.878 | 0.767 – 1 | 0.0574 | 258 | 2580 | exclusion | phecode |
| 1007 | Injury to blood vessels | Injuries & Poisonings | 1.09 | 0.957 – 1.24 | 0.19 | 256 | 2560 | exclusion | phecode |
| 1008 | Crushing or internal injury to organs | Injuries & Poisonings | 1.04 | 0.971 – 1.11 | 0.265 | 1014 | 10140 | exclusion | phecode |
| 1009 | Injury, NOS | Injuries & Poisonings | 1 | 0.981 – 1.03 | 0.781 | 8505 | 85048 | exclusion | phecode |
| 1010 | Other tests | Injuries & Poisonings | 1.02 | 0.99 – 1.05 | 0.207 | 5979 | 59790 | exclusion | phecode |
| 1011 | Complications of surgical and medical procedures | Injuries & Poisonings | 1.02 | 1 – 1.04 | 0.0548 | 9182 | 91820 | exclusion | phecode |
| 1012 | Late effect | Injuries & Poisonings | 0.897 | 0.73 – 1.1 | 0.296 | 106 | 1060 | exclusion | phecode |
| 1013 | Asphyxia and hypoxemia | Injuries & Poisonings | 1.1 | 0.977 – 1.23 | 0.112 | 317 | 3170 | exclusion | phecode |
| 1014 | Effects of heat, cold and air pressure | Injuries & Poisonings | 1.06 | 0.822 – 1.37 | 0.634 | 66 | 660 | exclusion | phecode |
| 1015 | Effects of other external causes | Injuries & Poisonings | 1.02 | 0.986 – 1.05 | 0.276 | 4237 | 42370 | exclusion | phecode |
| 1019 |
Other ill-defined and unknown causes ofOther ill-defined and unknown causes of morbidity and mortality
|
Injuries & Poisonings | 1 | 0.985 – 1.02 | 0.839 | 16056 | 160552 | exclusion | phecode |
| 110 | Dermatophytosis / Dermatomycosis | Infectious Diseases | 0.906 | 0.797 – 1.03 | 0.127 | 286 | 2860 | exclusion | phecode |
| 110.1 | Dermatophytosis | Infectious Diseases | 0.901 | 0.791 – 1.02 | 0.11 | 280 | 2800 | exclusion | phecode |
| 110.11 | Dermatophytosis of nail | Infectious Diseases | 0.907 | 0.701 – 1.17 | 0.446 | 76 | 760 | exclusion | phecode |
| 110.12 | Althete's foot | Infectious Diseases | 0.865 | 0.72 – 1.03 | 0.112 | 141 | 1410 | exclusion | phecode |
| 112 | Candidiasis | Infectious Diseases | 1.02 | 0.971 – 1.06 | 0.478 | 2134 | 21340 | exclusion | phecode |
| 117 | Mycoses | Infectious Diseases | 0.953 | 0.838 – 1.08 | 0.46 | 275 | 2750 | exclusion | phecode |
| 117.4 | Aspergillosis | Infectious Diseases | 0.918 | 0.777 – 1.08 | 0.305 | 165 | 1650 | exclusion | phecode |
| 130 | Spirochetal infection | Infectious Diseases | 0.877 | 0.69 – 1.11 | 0.267 | 80 | 800 | exclusion | phecode |
| 133 | Arthropod-borne diseases | Infectious Diseases | 0.922 | 0.707 – 1.19 | 0.538 | 70 | 700 | exclusion | phecode |
| 134 | Helminthiases | Infectious Diseases | 1.3 | 1.09 – 1.56 | 0.00375 | 129 | 1290 | exclusion | phecode |
| 134.1 | Intestinal helminthiases | Infectious Diseases | 1.3 | 1.07 – 1.58 | 0.00854 | 107 | 1070 | exclusion | phecode |
| 136 | Other infectious and parasitic diseases | Infectious Diseases | 1.04 | 0.9 – 1.21 | 0.565 | 207 | 2070 | exclusion | phecode |
| 145 | Cancer of mouth | Neoplasms | 1.02 | 0.939 – 1.11 | 0.601 | 648 | 6480 | exclusion | phecode |
| 145.2 | Cancer of tongue | Neoplasms | 0.995 | 0.881 – 1.12 | 0.936 | 310 | 3100 | exclusion | phecode |
| 145.3 | Cancer of major salivary glands | Neoplasms | 1.16 | 0.942 – 1.43 | 0.156 | 105 | 1050 | exclusion | phecode |
| 145.5 | Cancer of the mouth floor | Neoplasms | 0.823 | 0.604 – 1.11 | 0.197 | 54 | 540 | exclusion | phecode |
| 149 | Cancer of larynx, pharynx, nasal cavities | Neoplasms | 1.1 | 1.01 – 1.19 | 0.032 | 643 | 6428 | exclusion | phecode |
| 149.1 | Cancer of oropharynx | Neoplasms | 0.976 | 0.852 – 1.12 | 0.723 | 253 | 2528 | exclusion | phecode |
| 149.4 | Cancer of larynx | Neoplasms | 1.14 | 0.999 – 1.29 | 0.0506 | 265 | 2648 | exclusion | phecode |
| 149.9 | Cancer of of nasal cavities | Neoplasms | 1.21 | 0.895 – 1.64 | 0.196 | 57 | 570 | exclusion | phecode |
| 150 | Cancer of esophagus | Neoplasms | 0.982 | 0.909 – 1.06 | 0.649 | 764 | 7640 | exclusion | phecode |
| 151 | Cancer of stomach | Neoplasms | 0.972 | 0.888 – 1.06 | 0.526 | 570 | 5700 | exclusion | phecode |
| 153 | Colorectal cancer | Neoplasms | 1.01 | 0.974 – 1.04 | 0.75 | 4610 | 46100 | exclusion | phecode |
| 153.2 | Colon cancer | Neoplasms | 1.01 | 0.974 – 1.05 | 0.55 | 3109 | 31090 | exclusion | phecode |
| 153.3 |
Malignant neoplasm of rectum, rectosigmoidMalignant neoplasm of rectum, rectosigmoid junction, and anus
|
Neoplasms | 0.985 | 0.94 – 1.03 | 0.518 | 2165 | 21650 | exclusion | phecode |
| 155 | Cancer of liver and intrahepatic bile duct | Neoplasms | 0.989 | 0.889 – 1.1 | 0.838 | 402 | 4020 | exclusion | phecode |
| 155.1 | Malignant neoplasm of liver, primary | Neoplasms | 1.04 | 0.875 – 1.23 | 0.671 | 158 | 1580 | exclusion | phecode |
| 157 | Pancreatic cancer | Neoplasms | 0.987 | 0.909 – 1.07 | 0.759 | 659 | 6590 | exclusion | phecode |
| 158 |
Neoplasm of unspecified nature of digestiveNeoplasm of unspecified nature of digestive system
|
Neoplasms | 1.03 | 0.963 – 1.1 | 0.4 | 1064 | 10640 | exclusion | phecode |
| 159 |
Malignant neoplasm of other and ill-definedMalignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
|
Neoplasms | 0.998 | 0.97 – 1.03 | 0.909 | 5582 | 55820 | exclusion | phecode |
| 159.2 |
Malignant neoplasm of small intestineMalignant neoplasm of small intestine, including duodenum
|
Neoplasms | 1.08 | 0.925 – 1.26 | 0.327 | 189 | 1890 | exclusion | phecode |
| 159.3 |
Malignant neoplasm of gallbladder andMalignant neoplasm of gallbladder and extrahepatic bile ducts
|
Neoplasms | 0.89 | 0.764 – 1.03 | 0.127 | 205 | 2050 | exclusion | phecode |
| 159.4 |
Malignant neoplasm of retroperitoneum andMalignant neoplasm of retroperitoneum and peritoneum
|
Neoplasms | 0.956 | 0.819 – 1.11 | 0.569 | 192 | 1920 | exclusion | phecode |
| 164 | Cancer of intrathoracic organs | Neoplasms | 1.64 | 1.26 – 2.15 | 0.000258 | 60 | 600 | exclusion | phecode |
| 165 | Cancer within the respiratory system | Neoplasms | 1.06 | 1.02 – 1.11 | 0.00225 | 2833 | 28319 | exclusion | phecode |
| 165.1 | Cancer of bronchus; lung | Neoplasms | 1.06 | 1.01 – 1.11 | 0.01 | 2238 | 22380 | exclusion | phecode |
| 170 | Cancer of bone and connective tissue | Neoplasms | 1.01 | 0.908 – 1.12 | 0.881 | 445 | 4447 | exclusion | phecode |
| 170.1 | Bone cancer | Neoplasms | 1.09 | 0.901 – 1.31 | 0.37 | 131 | 1310 | exclusion | phecode |
| 170.2 | Cancer of connective tissue | Neoplasms | 1 | 0.887 – 1.13 | 0.992 | 331 | 3307 | exclusion | phecode |
| 172 | Skin cancer | Neoplasms | 1.73 | 0.00223 – 195 | 0.208 | 13624 | 136233 | exclusion | phecode |
| 172.1 | Melanomas of skin, dx or hx | Neoplasms | 0.951 | 0.552 – 1.59 | 0.831 | 2718 | 27180 | exclusion | phecode |
| 172.11 | Melanomas of skin | Neoplasms | 0.951 | 0.552 – 1.59 | 0.831 | 2718 | 27180 | exclusion | phecode |
| 172.2 | Other non-epithelial cancer of skin | Neoplasms | 0.866 | 0.514 – 1.42 | 0.53 | 11030 | 110298 | exclusion | phecode |
| 172.3 | Carcinoma in situ of skin | Neoplasms | 1.87 | 0.974 – 3.51 | 0.019 | 667 | 6670 | exclusion | phecode |
| 173 | Neoplasm of uncertain behavior of skin | Neoplasms | 1.13 | 0.947 – 1.34 | 0.17 | 182 | 1820 | exclusion | phecode |
| 174 | Breast cancer | Neoplasms | 1.01 | 0.993 – 1.03 | 0.219 | 12771 | 127136 | exclusion | phecode |
| 174.1 | Breast cancer [female] | Neoplasms | 1.01 | 0.994 – 1.03 | 0.18 | 12549 | 124973 | exclusion | phecode |
| 174.11 | Malignant neoplasm of female breast | Neoplasms | 1.02 | 0.997 – 1.04 | 0.099 | 11767 | 117670 | exclusion | phecode |
| 174.3 | Neoplasm of uncertain behavior of breast | Neoplasms | 0.933 | 0.764 – 1.14 | 0.487 | 115 | 1150 | exclusion | phecode |
| 175 | Acquired absence of breast | Neoplasms | 1.04 | 0.992 – 1.08 | 0.112 | 2406 | 24060 | exclusion | phecode |
| 180 | Cervical cancer and dysplasia | Neoplasms | 1 | 0.968 – 1.04 | 0.865 | 3640 | 36400 | exclusion | phecode |
| 180.1 | Cervical cancer | Neoplasms | 1.03 | 0.979 – 1.09 | 0.245 | 1655 | 16550 | exclusion | phecode |
| 180.3 |
Cervical intraepithelial neoplasia [CIN]Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
|
Neoplasms | 0.991 | 0.946 – 1.04 | 0.687 | 2081 | 20810 | exclusion | phecode |
| 182 | Malignant neoplasm of uterus | Neoplasms | 0.953 | 0.898 – 1.01 | 0.111 | 1288 | 12880 | exclusion | phecode |
| 184 | Cancer of other female genital organs | Neoplasms | 1.02 | 0.977 – 1.06 | 0.373 | 2467 | 24670 | exclusion | phecode |
| 184.1 |
Malignant neoplasm of ovary and other uterineMalignant neoplasm of ovary and other uterine adnexa
|
Neoplasms | 1.04 | 0.992 – 1.09 | 0.106 | 2131 | 21310 | exclusion | phecode |
| 184.11 | Malignant neoplasm of ovary | Neoplasms | 1.04 | 0.989 – 1.08 | 0.14 | 2108 | 21080 | exclusion | phecode |
| 184.2 |
Cancer of other female genital organsCancer of other female genital organs (excluding uterus and ovary)
|
Neoplasms | 0.923 | 0.813 – 1.05 | 0.21 | 305 | 3050 | exclusion | phecode |
| 185 | Cancer of prostate | Neoplasms | 0.996 | 0.97 – 1.02 | 0.78 | 6719 | 64751 | exclusion | phecode |
| 187 | Cancer of other male genital organs | Neoplasms | 0.991 | 0.954 – 1.03 | 0.662 | 3114 | 31140 | exclusion | phecode |
| 187.1 |
Malignant neoplasm of unspecified male genitalMalignant neoplasm of unspecified male genital organ
|
Neoplasms | 0.98 | 0.941 – 1.02 | 0.333 | 2835 | 28350 | exclusion | phecode |
| 187.2 | Malignant neoplasm of testis | Neoplasms | 0.987 | 0.949 – 1.03 | 0.522 | 2973 | 29730 | exclusion | phecode |
| 187.8 |
Neoplasm of uncertain behavior of male genitalNeoplasm of uncertain behavior of male genital organs
|
Neoplasms | 1.09 | 0.894 – 1.33 | 0.378 | 110 | 1100 | exclusion | phecode |
| 189 |
Cancer of urinary organs (incl. kidney andCancer of urinary organs (incl. kidney and bladder)
|
Neoplasms | 1.01 | 0.974 – 1.04 | 0.694 | 4183 | 41830 | exclusion | phecode |
| 189.1 | Cancer of kidney and renal pelvis | Neoplasms | 1 | 0.938 – 1.07 | 0.966 | 1075 | 10750 | exclusion | phecode |
| 189.11 | Malignant neoplasm of kidney, except pelvis | Neoplasms | 0.991 | 0.928 – 1.06 | 0.794 | 1032 | 10320 | exclusion | phecode |
| 189.12 | Malignant neoplasm of renal pelvis | Neoplasms | 1.18 | 0.9 – 1.54 | 0.219 | 66 | 660 | exclusion | phecode |
| 189.2 | Cancer of bladder | Neoplasms | 1.01 | 0.964 – 1.05 | 0.78 | 2424 | 24240 | exclusion | phecode |
| 189.21 | Malignant neoplasm of bladder | Neoplasms | 0.986 | 0.942 – 1.03 | 0.551 | 2148 | 21480 | exclusion | phecode |
| 189.4 | Malignant neoplasm of other urinary organs | Neoplasms | 1.12 | 0.936 – 1.34 | 0.21 | 144 | 1440 | exclusion | phecode |
| 190 | Cancer of eye | Neoplasms | 1.26 | 1.07 – 1.48 | 0.00624 | 176 | 1760 | exclusion | phecode |
| 191 |
Manlignant and unknown neoplasms of brain andManlignant and unknown neoplasms of brain and nervous system
|
Neoplasms | 0.995 | 0.918 – 1.08 | 0.911 | 692 | 6920 | exclusion | phecode |
| 191.1 | Cancer of brain and nervous system | Neoplasms | 0.984 | 0.9 – 1.08 | 0.723 | 568 | 5680 | exclusion | phecode |
| 191.11 | Cancer of brain | Neoplasms | 0.98 | 0.893 – 1.07 | 0.669 | 524 | 5240 | exclusion | phecode |
| 193 | Thyroid cancer | Neoplasms | 1.13 | 1.01 – 1.26 | 0.034 | 358 | 3580 | exclusion | phecode |
| 194 | Cancer of other endocrine glands | Neoplasms | 1.01 | 0.814 – 1.25 | 0.92 | 95 | 950 | exclusion | phecode |
| 195 | Cancer, suspected or other | Neoplasms | 1.02 | 1.01 – 1.04 | 0.00688 | 17028 | 165982 | exclusion | phecode |
| 195.1 | Malignant neoplasm, other | Neoplasms | 1.03 | 1.01 – 1.05 | 0.00392 | 16305 | 159816 | exclusion | phecode |
| 197 | Chemotherapy | Neoplasms | 1.02 | 1 – 1.03 | 0.0418 | 21492 | 213706 | exclusion | phecode |
| 198 | Secondary malignant neoplasm | Neoplasms | 1.02 | 0.999 – 1.04 | 0.0587 | 9585 | 95830 | exclusion | phecode |
| 198.1 | Secondary malignancy of lymph nodes | Neoplasms | 1.03 | 0.998 – 1.06 | 0.0642 | 5355 | 53549 | exclusion | phecode |
| 198.2 | Secondary malignancy of respiratory organs | Neoplasms | 1 | 0.955 – 1.05 | 0.993 | 2263 | 22619 | exclusion | phecode |
| 198.3 |
Secondary malignant neoplasm of digestiveSecondary malignant neoplasm of digestive systems
|
Neoplasms | 1.02 | 0.964 – 1.08 | 0.514 | 1542 | 15416 | exclusion | phecode |
| 198.4 | Secondary malignant neoplasm of liver | Neoplasms | 1.01 | 0.971 – 1.06 | 0.562 | 2661 | 26602 | exclusion | phecode |
| 198.5 | Secondary malignancy of brain/spine | Neoplasms | 1.02 | 0.95 – 1.1 | 0.529 | 846 | 8460 | exclusion | phecode |
| 198.6 | Secondary malignancy of bone | Neoplasms | 1.02 | 0.978 – 1.07 | 0.307 | 2156 | 21553 | exclusion | phecode |
| 198.7 | Secondary malignant neoplasm of skin | Neoplasms | 1.1 | 0.907 – 1.32 | 0.333 | 187 | 1869 | exclusion | phecode |
| 199 | Neoplasm of uncertain behavior | Neoplasms | 1.04 | 0.985 – 1.1 | 0.153 | 1433 | 14330 | exclusion | phecode |
| 199.4 | Neurofibromatosis | Neoplasms | 0.887 | 0.711 – 1.1 | 0.279 | 95 | 950 | exclusion | phecode |
| 200 | Myeloproliferative disease | Neoplasms | 0.992 | 0.927 – 1.06 | 0.815 | 1000 | 10000 | exclusion | phecode |
| 200.1 | Polycythemia vera | Neoplasms | 0.987 | 0.885 – 1.1 | 0.805 | 390 | 3900 | exclusion | phecode |
| 201 | Hodgkin's disease | Neoplasms | 1 | 0.877 – 1.14 | 0.999 | 261 | 2610 | exclusion | phecode |
| 202 | Cancer of other lymphoid, histiocytic tissue | Neoplasms | 1.01 | 0.962 – 1.05 | 0.797 | 2297 | 22970 | exclusion | phecode |
| 202.2 | Non-Hodgkins lymphoma | Neoplasms | 1 | 0.951 – 1.05 | 0.994 | 1821 | 18210 | exclusion | phecode |
| 202.21 | Nodular lymphoma | Neoplasms | 0.977 | 0.873 – 1.09 | 0.68 | 370 | 3700 | exclusion | phecode |
| 202.24 | Large cell lymphoma | Neoplasms | 1.01 | 0.925 – 1.1 | 0.817 | 584 | 5840 | exclusion | phecode |
| 204 | Leukemia | Neoplasms | 1.02 | 0.965 – 1.07 | 0.522 | 1696 | 16954 | exclusion | phecode |
| 204.1 | Lymphoid leukemia | Neoplasms | 1.06 | 0.971 – 1.16 | 0.183 | 587 | 5864 | exclusion | phecode |
| 204.11 | Lymphoid leukemia, acute | Neoplasms | 0.861 | 0.648 – 1.13 | 0.281 | 60 | 600 | exclusion | phecode |
| 204.12 | Lymphoid leukemia, chronic | Neoplasms | 1.07 | 0.971 – 1.18 | 0.169 | 514 | 5134 | exclusion | phecode |
| 204.2 | Myeloid leukemia | Neoplasms | 0.946 | 0.857 – 1.04 | 0.265 | 486 | 4860 | exclusion | phecode |
| 204.21 | Myeloid leukemia, acute | Neoplasms | 0.957 | 0.85 – 1.08 | 0.457 | 336 | 3360 | exclusion | phecode |
| 204.22 | Myeloid leukemia, chronic | Neoplasms | 0.929 | 0.78 – 1.1 | 0.402 | 157 | 1570 | exclusion | phecode |
| 204.4 | Multiple myeloma | Neoplasms | 1.06 | 0.973 – 1.16 | 0.17 | 559 | 5590 | exclusion | phecode |
| 208 | Benign neoplasm of colon | Neoplasms | 1.03 | 1.01 – 1.04 | 0.00113 | 19890 | 192225 | exclusion | phecode |
| 210 | Benign neoplasm of lip, oral cavity, and pharynx | Neoplasms | 1.04 | 0.976 – 1.12 | 0.206 | 981 | 9810 | exclusion | phecode |
| 211 |
Benign neoplasm of other parts of digestiveBenign neoplasm of other parts of digestive system
|
Neoplasms | 1.01 | 0.98 – 1.04 | 0.562 | 5256 | 52560 | exclusion | phecode |
| 212 |
Benign neoplasm of respiratory andBenign neoplasm of respiratory and intrathoracic organs
|
Neoplasms | 1.03 | 0.917 – 1.15 | 0.635 | 348 | 3480 | exclusion | phecode |
| 213 | Benign neoplasm of bone and articular cartilage | Neoplasms | 1.18 | 1.05 – 1.32 | 0.00606 | 320 | 3200 | exclusion | phecode |
| 214 | Lipoma | Neoplasms | 0.996 | 0.969 – 1.02 | 0.761 | 6246 | 62460 | exclusion | phecode |
| 214.1 | Lipoma of skin and subcutaneous tissue | Neoplasms | 0.998 | 0.967 – 1.03 | 0.884 | 4593 | 45930 | exclusion | phecode |
| 215 |
Other benign neoplasm of connective and otherOther benign neoplasm of connective and other soft tissue
|
Neoplasms | 1 | 0.941 – 1.07 | 0.925 | 1109 | 11090 | exclusion | phecode |
| 216 | Benign neoplasm of skin | Neoplasms | 0.944 | 0.92 – 0.968 | 1.08e-05 | 7679 | 76785 | exclusion | phecode |
| 217 | Vascular hamartomas and non-neoplastic nevi | Neoplasms | 1.02 | 0.938 – 1.11 | 0.616 | 649 | 6490 | exclusion | phecode |
| 217.1 | Nevus, non-neoplastic | Neoplasms | 0.996 | 0.91 – 1.09 | 0.933 | 597 | 5970 | exclusion | phecode |
| 218 | Benign neoplasm of uterus | Neoplasms | 1.01 | 0.992 – 1.03 | 0.249 | 10507 | 105069 | exclusion | phecode |
| 218.1 | Uterine leiomyoma | Neoplasms | 1.01 | 0.993 – 1.04 | 0.194 | 10245 | 102449 | exclusion | phecode |
| 218.2 | Other benign neoplasm of uterus | Neoplasms | 0.955 | 0.852 – 1.07 | 0.429 | 353 | 3530 | exclusion | phecode |
| 220 | Benign neoplasm of ovary | Neoplasms | 1.05 | 0.995 – 1.11 | 0.0768 | 1476 | 14760 | exclusion | phecode |
| 221 | Benign neoplasm of other female genital organs | Neoplasms | 1.09 | 0.945 – 1.26 | 0.232 | 220 | 2200 | exclusion | phecode |
| 222 | Benign neoplasm of male genital organs | Neoplasms | 0.893 | 0.753 – 1.06 | 0.185 | 160 | 1600 | exclusion | phecode |
| 223 |
Benign neoplasm of kidney and other urinaryBenign neoplasm of kidney and other urinary organs
|
Neoplasms | 1.05 | 0.896 – 1.24 | 0.523 | 174 | 1740 | exclusion | phecode |
| 224 | Benign neoplasm of eye | Neoplasms | 1.07 | 0.884 – 1.28 | 0.496 | 130 | 1300 | exclusion | phecode |
| 224.1 | Benign neoplasm of eye, uveal | Neoplasms | 1.21 | 0.942 – 1.56 | 0.125 | 68 | 680 | exclusion | phecode |
| 225 |
Benign neoplasm of brain and other parts ofBenign neoplasm of brain and other parts of nervous system
|
Neoplasms | 1.02 | 0.944 – 1.09 | 0.655 | 830 | 8300 | exclusion | phecode |
| 225.1 |
Benign neoplasm of brain, cranial nervesBenign neoplasm of brain, cranial nerves, meninges
|
Neoplasms | 1.02 | 0.943 – 1.1 | 0.637 | 776 | 7760 | exclusion | phecode |
| 225.2 | Benign neoplasm of spinal cord, meninges | Neoplasms | 1 | 0.762 – 1.31 | 0.982 | 59 | 590 | exclusion | phecode |
| 226 | Benign neoplasm of thyroid glands | Neoplasms | 1.02 | 0.903 – 1.16 | 0.703 | 285 | 2850 | exclusion | phecode |
| 227 |
Benign neoplasm of other endocrine glands andBenign neoplasm of other endocrine glands and related structures
|
Neoplasms | 1.05 | 0.982 – 1.13 | 0.142 | 878 | 8780 | exclusion | phecode |
| 227.1 | Benign neoplasm of adrenal gland | Neoplasms | 1.07 | 0.918 – 1.25 | 0.38 | 186 | 1860 | exclusion | phecode |
| 227.2 | Benign neoplasm of parathyroid gland | Neoplasms | 1.13 | 1.01 – 1.26 | 0.0297 | 371 | 3710 | exclusion | phecode |
| 227.3 |
Benign neoplasm of pituitary gland andBenign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
|
Neoplasms | 0.976 | 0.865 – 1.1 | 0.695 | 311 | 3110 | exclusion | phecode |
| 228 | Hemangioma and lymphangioma, any site | Neoplasms | 1.03 | 0.972 – 1.08 | 0.349 | 1602 | 16020 | exclusion | phecode |
| 229 | Benign neoplasm of unspecified sites | Neoplasms | 0.886 | 0.846 – 0.927 | 2.04e-07 | 2400 | 23998 | exclusion | phecode |
| 240 | Simple and unspecified goiter | Endocrine/metabolic | 0.992 | 0.909 – 1.08 | 0.853 | 602 | 6020 | exclusion | phecode |
| 241 | Nontoxic nodular goiter | Endocrine/metabolic | 0.974 | 0.914 – 1.04 | 0.419 | 1142 | 11420 | exclusion | phecode |
| 241.1 | Nontoxic uninodular goiter | Endocrine/metabolic | 0.926 | 0.838 – 1.02 | 0.128 | 472 | 4720 | exclusion | phecode |
| 241.2 | Nontoxic multinodular goiter | Endocrine/metabolic | 1.02 | 0.94 – 1.11 | 0.618 | 679 | 6790 | exclusion | phecode |
| 242 | Thyrotoxicosis with or without goiter | Endocrine/metabolic | 1.01 | 0.966 – 1.07 | 0.57 | 1849 | 18490 | exclusion | phecode |
| 242.1 | Graves' disease | Endocrine/metabolic | 1.01 | 0.911 – 1.11 | 0.907 | 456 | 4560 | exclusion | phecode |
| 242.2 | Toxic multinodular goiter | Endocrine/metabolic | 1.24 | 1 – 1.53 | 0.0411 | 91 | 910 | exclusion | phecode |
| 242.3 | Exophthalmos | Endocrine/metabolic | 0.968 | 0.804 – 1.16 | 0.727 | 129 | 1290 | exclusion | phecode |
| 244 | Hypothyroidism | Endocrine/metabolic | 0.997 | 0.98 – 1.01 | 0.751 | 14646 | 145476 | exclusion | phecode |
| 244.1 | Secondary hypothyroidism | Endocrine/metabolic | 1.03 | 0.966 – 1.1 | 0.362 | 1111 | 11110 | exclusion | phecode |
| 244.2 | Acquired hypothyroidism | Endocrine/metabolic | 1.15 | 0.929 – 1.41 | 0.196 | 101 | 1010 | exclusion | phecode |
| 244.4 | Hypothyroidism NOS | Endocrine/metabolic | 0.994 | 0.976 – 1.01 | 0.495 | 13961 | 139245 | exclusion | phecode |
| 245 | Thyroiditis | Endocrine/metabolic | 0.945 | 0.834 – 1.07 | 0.372 | 294 | 2940 | exclusion | phecode |
| 245.2 | Chronic thyroiditis | Endocrine/metabolic | 0.969 | 0.841 – 1.12 | 0.664 | 224 | 2240 | exclusion | phecode |
| 245.21 | Chronic lymphocytic thyroiditis | Endocrine/metabolic | 0.948 | 0.818 – 1.1 | 0.468 | 211 | 2110 | exclusion | phecode |
| 246 | Other disorders of thyroid | Endocrine/metabolic | 0.969 | 0.871 – 1.08 | 0.564 | 403 | 4030 | exclusion | phecode |
| 250 | Diabetes mellitus | Endocrine/metabolic | 1.02 | 1 – 1.03 | 0.0436 | 19898 | 186647 | exclusion | phecode |
| 250.1 | Type 1 diabetes | Endocrine/metabolic | 1.03 | 0.991 – 1.08 | 0.122 | 2657 | 26570 | exclusion | phecode |
| 250.11 | Type 1 diabetes with ketoacidosis | Endocrine/metabolic | 0.993 | 0.866 – 1.14 | 0.923 | 239 | 2390 | exclusion | phecode |
| 250.12 | Type 1 diabetes with renal manifestations | Endocrine/metabolic | 1.06 | 0.832 – 1.34 | 0.646 | 77 | 770 | exclusion | phecode |
| 250.2 | Type 2 diabetes | Endocrine/metabolic | 1.01 | 0.999 – 1.03 | 0.0725 | 18671 | 176412 | exclusion | phecode |
| 250.21 | Type 2 diabetes with ketoacidosis | Endocrine/metabolic | 1.11 | 0.907 – 1.37 | 0.295 | 105 | 1050 | exclusion | phecode |
| 250.22 | Type 2 diabetes with renal manifestations | Endocrine/metabolic | 1.05 | 0.908 – 1.22 | 0.488 | 202 | 2020 | exclusion | phecode |
| 250.23 | Type 2 diabetes with ophthalmic manifestations | Endocrine/metabolic | 1.02 | 0.958 – 1.08 | 0.603 | 1294 | 12940 | exclusion | phecode |
| 250.24 | Type 2 diabetes with neurological manifestations | Endocrine/metabolic | 1.08 | 0.987 – 1.18 | 0.0921 | 575 | 5750 | exclusion | phecode |
| 250.4 | Abnormal glucose | Endocrine/metabolic | 0.99 | 0.912 – 1.07 | 0.802 | 684 | 6840 | exclusion | phecode |
| 250.41 | Impaired fasting glucose | Endocrine/metabolic | 1.01 | 0.887 – 1.16 | 0.852 | 266 | 2660 | exclusion | phecode |
| 250.42 | Other abnormal glucose | Endocrine/metabolic | 0.993 | 0.894 – 1.1 | 0.887 | 419 | 4190 | exclusion | phecode |
| 250.5 | Glycosuria or Acetonuria | Endocrine/metabolic | 1.01 | 0.839 – 1.21 | 0.921 | 131 | 1310 | exclusion | phecode |
| 250.6 | Polyneuropathy in diabetes | Endocrine/metabolic | 1.05 | 0.936 – 1.17 | 0.413 | 354 | 3540 | exclusion | phecode |
| 250.7 | Diabetic retinopathy | Endocrine/metabolic | 1 | 0.945 – 1.06 | 0.949 | 1335 | 13350 | exclusion | phecode |
| 251.1 | Hypoglycemia | Endocrine/metabolic | 1.05 | 0.984 – 1.13 | 0.133 | 940 | 9395 | exclusion | phecode |
| 252 | Disorders of parathyroid gland | Endocrine/metabolic | 1.02 | 0.946 – 1.09 | 0.647 | 877 | 8770 | exclusion | phecode |
| 252.1 | Hyperparathyroidism | Endocrine/metabolic | 1.01 | 0.937 – 1.09 | 0.764 | 781 | 7810 | exclusion | phecode |
| 252.2 | Hypoparathyroidism | Endocrine/metabolic | 1 | 0.835 – 1.2 | 0.979 | 142 | 1420 | exclusion | phecode |
| 253 |
Disorders of the pituitary gland and itsDisorders of the pituitary gland and its hypothalamic control
|
Endocrine/metabolic | 1.02 | 0.939 – 1.1 | 0.668 | 694 | 6940 | exclusion | phecode |
| 253.1 | Pituitary hyperfunction | Endocrine/metabolic | 0.923 | 0.788 – 1.08 | 0.314 | 189 | 1890 | exclusion | phecode |
| 253.11 | Acromegaly and gigantism | Endocrine/metabolic | 0.921 | 0.737 – 1.15 | 0.462 | 95 | 950 | exclusion | phecode |
| 253.2 | Pituitary hypofunction | Endocrine/metabolic | 1.04 | 0.913 – 1.19 | 0.536 | 263 | 2630 | exclusion | phecode |
| 253.3 | Diabetes insipidus | Endocrine/metabolic | 1.23 | 0.99 – 1.53 | 0.0577 | 93 | 930 | exclusion | phecode |
| 253.7 | Other disorders of neurohypophysis | Endocrine/metabolic | 1.02 | 0.865 – 1.21 | 0.774 | 158 | 1580 | exclusion | phecode |
| 255 | Disorders of adrenal glands | Endocrine/metabolic | 0.96 | 0.882 – 1.04 | 0.338 | 642 | 6420 | exclusion | phecode |
| 255.1 | Adrenal hyperfunction | Endocrine/metabolic | 1.09 | 0.932 – 1.27 | 0.273 | 182 | 1820 | exclusion | phecode |
| 255.11 | Cushing's syndrome | Endocrine/metabolic | 1.03 | 0.836 – 1.26 | 0.772 | 103 | 1030 | exclusion | phecode |
| 255.12 | Hyperaldosteronism | Endocrine/metabolic | 1.17 | 0.923 – 1.49 | 0.183 | 76 | 760 | exclusion | phecode |
| 255.2 | Adrenal hypofunction | Endocrine/metabolic | 0.919 | 0.82 – 1.03 | 0.139 | 364 | 3640 | exclusion | phecode |
| 255.21 | Glucocorticoid deficiency | Endocrine/metabolic | 0.913 | 0.814 – 1.02 | 0.114 | 361 | 3610 | exclusion | phecode |
| 256 | Ovarian dysfunction | Endocrine/metabolic | 0.933 | 0.815 – 1.07 | 0.313 | 244 | 2440 | exclusion | phecode |
| 256.4 | Polycystic ovaries | Endocrine/metabolic | 0.924 | 0.798 – 1.07 | 0.288 | 209 | 2090 | exclusion | phecode |
| 257 | Testicular dysfunction | Endocrine/metabolic | 1.11 | 0.936 – 1.31 | 0.23 | 163 | 1630 | exclusion | phecode |
| 257.1 | Testicular hypofunction | Endocrine/metabolic | 1.09 | 0.921 – 1.3 | 0.299 | 154 | 1540 | exclusion | phecode |
| 258 | Iatrogenic endocrine disorders | Endocrine/metabolic | 1.04 | 0.842 – 1.28 | 0.71 | 102 | 1020 | exclusion | phecode |
| 259 | Other endocrine disorders | Endocrine/metabolic | 1.1 | 0.93 – 1.3 | 0.254 | 152 | 1520 | exclusion | phecode |
| 260 | Protein-calorie malnutrition | Endocrine/metabolic | 1.11 | 0.956 – 1.29 | 0.168 | 202 | 2019 | exclusion | phecode |
| 261 | Vitamin deficiency | Endocrine/metabolic | 1.03 | 0.968 – 1.09 | 0.357 | 1210 | 12100 | exclusion | phecode |
| 261.2 | Vitamin B-complex deficiencies | Endocrine/metabolic | 1 | 0.928 – 1.08 | 0.947 | 755 | 7550 | exclusion | phecode |
| 261.4 | Vitamin D deficiency | Endocrine/metabolic | 1.04 | 0.938 – 1.15 | 0.48 | 449 | 4490 | exclusion | phecode |
| 261.41 | Rickets or osteomalacia | Endocrine/metabolic | 0.904 | 0.703 – 1.15 | 0.415 | 77 | 770 | exclusion | phecode |
| 262 | Mineral deficiency NEC | Endocrine/metabolic | 1.01 | 0.879 – 1.15 | 0.921 | 242 | 2420 | exclusion | phecode |
| 269 | Proteinuria | Endocrine/metabolic | 0.996 | 0.887 – 1.12 | 0.939 | 339 | 3390 | exclusion | phecode |
| 270 |
Disorders of protein plasma/amino-acidDisorders of protein plasma/amino-acid transport and metabolism
|
Endocrine/metabolic | 0.991 | 0.874 – 1.12 | 0.885 | 304 | 3040 | exclusion | phecode |
| 270.3 | Disorders of plasma protein metabolism | Endocrine/metabolic | 0.974 | 0.851 – 1.11 | 0.706 | 261 | 2610 | exclusion | phecode |
| 270.32 | Paraproteinemia | Endocrine/metabolic | 0.952 | 0.813 – 1.11 | 0.532 | 191 | 1910 | exclusion | phecode |
| 270.35 | Macroglobulinemia | Endocrine/metabolic | 1.01 | 0.769 – 1.32 | 0.939 | 69 | 690 | exclusion | phecode |
| 271 |
Disorders of carbohydrate transport andDisorders of carbohydrate transport and metabolism
|
Endocrine/metabolic | 0.969 | 0.818 – 1.15 | 0.713 | 163 | 1621 | exclusion | phecode |
| 271.3 |
Intestinal disaccharidase deficiencies andIntestinal disaccharidase deficiencies and disaccharide malabsorption
|
Endocrine/metabolic | 0.922 | 0.768 – 1.1 | 0.374 | 141 | 1401 | exclusion | phecode |
| 272 | Disorders of lipoid metabolism | Endocrine/metabolic | 1 | 0.991 – 1.01 | 0.697 | 34960 | 235908 | exclusion | phecode |
| 272.1 | Hyperlipidemia | Endocrine/metabolic | 1 | 0.991 – 1.01 | 0.688 | 34878 | 235352 | exclusion | phecode |
| 272.11 | Hypercholesterolemia | Endocrine/metabolic | 1 | 0.991 – 1.02 | 0.626 | 32352 | 218140 | exclusion | phecode |
| 272.12 | Hyperglyceridemia | Endocrine/metabolic | 1.05 | 0.793 – 1.37 | 0.732 | 58 | 580 | exclusion | phecode |
| 272.13 | Mixed hyperlipidemia | Endocrine/metabolic | 0.88 | 0.742 – 1.04 | 0.132 | 164 | 1638 | exclusion | phecode |
| 272.9 | Unspecified disorder of lipoid metabolism | Endocrine/metabolic | 1.08 | 0.928 – 1.24 | 0.33 | 211 | 2110 | exclusion | phecode |
| 274 | Gout and other crystal arthropathies | Endocrine/metabolic | 1.01 | 0.978 – 1.05 | 0.484 | 3742 | 37420 | exclusion | phecode |
| 274.1 | Gout | Endocrine/metabolic | 1.01 | 0.976 – 1.05 | 0.471 | 3176 | 31760 | exclusion | phecode |
| 274.11 | Gouty arthropathy | Endocrine/metabolic | 1.17 | 0.956 – 1.42 | 0.123 | 111 | 1110 | exclusion | phecode |
| 274.2 | Crystal arthropathies | Endocrine/metabolic | 1.01 | 0.923 – 1.09 | 0.903 | 614 | 6140 | exclusion | phecode |
| 274.21 | Chondrocalcinosis | Endocrine/metabolic | 0.998 | 0.912 – 1.09 | 0.961 | 559 | 5590 | exclusion | phecode |
| 275 | Disorders of mineral metabolism | Endocrine/metabolic | 1.01 | 0.962 – 1.06 | 0.751 | 2116 | 21160 | exclusion | phecode |
| 275.1 | Disorders of iron metabolism | Hematopoietic | 1 | 0.923 – 1.09 | 0.927 | 657 | 6570 | exclusion | phecode |
| 275.3 | Disorders of magnesium metabolism | Endocrine/metabolic | 0.957 | 0.854 – 1.07 | 0.445 | 374 | 3740 | exclusion | phecode |
| 275.5 | Disorders of calcium/phosphorus metabolism | Endocrine/metabolic | 1.03 | 0.967 – 1.09 | 0.373 | 1205 | 12050 | exclusion | phecode |
| 275.53 | Disorders of phosphorus metabolism | Endocrine/metabolic | 1.04 | 0.883 – 1.23 | 0.626 | 172 | 1720 | exclusion | phecode |
| 276 |
Disorders of fluid, electrolyte, and acid-baseDisorders of fluid, electrolyte, and acid-base balance
|
Endocrine/metabolic | 1.02 | 0.991 – 1.04 | 0.205 | 7342 | 73420 | exclusion | phecode |
| 276.1 | Electrolyte imbalance | Endocrine/metabolic | 1.02 | 0.99 – 1.06 | 0.167 | 4113 | 41130 | exclusion | phecode |
| 276.11 | Hyperosmolality and/or hypernatremia | Endocrine/metabolic | 1.07 | 0.933 – 1.22 | 0.329 | 239 | 2390 | exclusion | phecode |
| 276.12 | Hyposmolality and/or hyponatremia | Endocrine/metabolic | 1.04 | 0.987 – 1.09 | 0.142 | 1822 | 18220 | exclusion | phecode |
| 276.13 | Hyperpotassemia | Endocrine/metabolic | 0.978 | 0.913 – 1.05 | 0.526 | 977 | 9770 | exclusion | phecode |
| 276.14 | Hypopotassemia | Endocrine/metabolic | 1.04 | 0.978 – 1.09 | 0.231 | 1422 | 14220 | exclusion | phecode |
| 276.4 | Acid-base balance disorder | Endocrine/metabolic | 1 | 0.943 – 1.07 | 0.911 | 1160 | 11600 | exclusion | phecode |
| 276.41 | Acidosis | Endocrine/metabolic | 1.02 | 0.955 – 1.09 | 0.554 | 1059 | 10590 | exclusion | phecode |
| 276.42 | Alkalosis | Endocrine/metabolic | 0.858 | 0.699 – 1.05 | 0.135 | 112 | 1120 | exclusion | phecode |
| 276.5 | Hypovolemia | Endocrine/metabolic | 1.01 | 0.972 – 1.05 | 0.55 | 2825 | 28250 | exclusion | phecode |
| 276.6 | Fluid overload | Endocrine/metabolic | 0.951 | 0.858 – 1.05 | 0.335 | 455 | 4550 | exclusion | phecode |
| 277 | Other disorders of metabolism | Endocrine/metabolic | 1.06 | 0.988 – 1.14 | 0.103 | 905 | 9048 | exclusion | phecode |
| 277.5 | Other disorders of lipoid metabolism | Endocrine/metabolic | 0.871 | 0.673 – 1.12 | 0.279 | 75 | 750 | exclusion | phecode |
| 277.51 | Lipoprotein disorders | Endocrine/metabolic | 0.91 | 0.67 – 1.22 | 0.529 | 52 | 520 | exclusion | phecode |
| 278 | Overweight, obesity and other hyperalimentation | Endocrine/metabolic | 1.02 | 1 – 1.04 | 0.0444 | 10863 | 108629 | exclusion | phecode |
| 278.1 | Obesity | Endocrine/metabolic | 1.02 | 1 – 1.04 | 0.0437 | 10696 | 106959 | exclusion | phecode |
| 278.3 | Localized adiposity | Endocrine/metabolic | 0.918 | 0.723 – 1.16 | 0.472 | 83 | 830 | exclusion | phecode |
| 278.4 | Abnormal weight gain | Endocrine/metabolic | 1 | 0.771 – 1.3 | 0.974 | 66 | 660 | exclusion | phecode |
| 279 | Disorders involving the immune mechanism | Endocrine/metabolic | 0.956 | 0.834 – 1.09 | 0.509 | 252 | 2520 | exclusion | phecode |
| 279.1 | Immunity deficiency | Endocrine/metabolic | 0.982 | 0.847 – 1.14 | 0.809 | 211 | 2110 | exclusion | phecode |
| 279.11 | Deficiency of humoral immunity | Endocrine/metabolic | 1.02 | 0.853 – 1.22 | 0.803 | 140 | 1400 | exclusion | phecode |
| 280 | Iron deficiency anemias | Hematopoietic | 1.03 | 1 – 1.05 | 0.0295 | 7750 | 77478 | exclusion | phecode |
| 280.1 |
Iron deficiency anemias, unspecified or not dueIron deficiency anemias, unspecified or not due to blood loss
|
Hematopoietic | 1.02 | 0.999 – 1.05 | 0.0618 | 7378 | 73758 | exclusion | phecode |
| 280.2 |
Iron deficiency anemia secondary to blood lossIron deficiency anemia secondary to blood loss (chronic)
|
Hematopoietic | 1.14 | 1.04 – 1.26 | 0.00696 | 455 | 4550 | exclusion | phecode |
| 281 | Other deficiency anemia | Hematopoietic | 1.08 | 1.02 – 1.15 | 0.0116 | 1131 | 11310 | exclusion | phecode |
| 281.1 | Megaloblastic anemia | Hematopoietic | 1.09 | 1.02 – 1.16 | 0.0116 | 1074 | 10740 | exclusion | phecode |
| 281.11 | Pernicious anemia | Hematopoietic | 1.09 | 1.01 – 1.17 | 0.0338 | 752 | 7520 | exclusion | phecode |
| 281.12 | Other vitamin B12 deficiency anemia | Hematopoietic | 0.976 | 0.831 – 1.15 | 0.77 | 178 | 1780 | exclusion | phecode |
| 281.13 | Folate-deficiency anemia | Hematopoietic | 1.14 | 0.978 – 1.33 | 0.0897 | 186 | 1860 | exclusion | phecode |
| 281.9 | Deficiency anemias | Hematopoietic | 1.06 | 0.795 – 1.41 | 0.678 | 54 | 540 | exclusion | phecode |
| 282 | Hereditary hemolytic anemias | Hematopoietic | 0.909 | 0.765 – 1.08 | 0.267 | 157 | 1570 | exclusion | phecode |
| 282.8 | Other hemoglobinopathies | Hematopoietic | 0.939 | 0.706 – 1.24 | 0.652 | 56 | 560 | exclusion | phecode |
| 282.9 | Other hereditary hemolytic anemias | Hematopoietic | 0.884 | 0.7 – 1.11 | 0.289 | 85 | 850 | exclusion | phecode |
| 283 | Acquired hemolytic anemias | Hematopoietic | 1.01 | 0.844 – 1.21 | 0.896 | 143 | 1430 | exclusion | phecode |
| 283.1 | Autoimmune hemolytic anemias | Hematopoietic | 0.99 | 0.802 – 1.22 | 0.925 | 107 | 1070 | exclusion | phecode |
| 284 | Aplastic anemia | Hematopoietic | 0.995 | 0.897 – 1.1 | 0.918 | 440 | 4400 | exclusion | phecode |
| 285 | Other anemias | Hematopoietic | 1.02 | 1 – 1.04 | 0.0554 | 12138 | 121369 | exclusion | phecode |
| 285.1 | Acute posthemorrhagic anemia | Hematopoietic | 0.959 | 0.841 – 1.09 | 0.532 | 269 | 2690 | exclusion | phecode |
| 285.2 | Anemia of chronic disease | Hematopoietic | 1.05 | 0.963 – 1.14 | 0.282 | 693 | 6930 | exclusion | phecode |
| 285.22 | Anemia in neoplastic disease | Hematopoietic | 1.07 | 0.964 – 1.19 | 0.2 | 412 | 4120 | exclusion | phecode |
| 286 | Coagulation defects | Hematopoietic | 0.994 | 0.927 – 1.06 | 0.859 | 929 | 9290 | exclusion | phecode |
| 286.1 | Congenital coagulation defects | Hematopoietic | 0.992 | 0.899 – 1.09 | 0.877 | 460 | 4600 | exclusion | phecode |
| 286.11 | Von willebrand's disease | Hematopoietic | 0.949 | 0.761 – 1.18 | 0.636 | 96 | 960 | exclusion | phecode |
| 286.12 |
Congenital deficiency of other clotting factorsCongenital deficiency of other clotting factors (including factor VII)
|
Hematopoietic | 1.02 | 0.902 – 1.15 | 0.746 | 294 | 2940 | exclusion | phecode |
| 286.13 | Congenital factor VIII disorder | Hematopoietic | 1.05 | 0.805 – 1.35 | 0.723 | 63 | 630 | exclusion | phecode |
| 286.5 |
Hemorrhagic disorder due to intrinsicHemorrhagic disorder due to intrinsic circulating anticoagulants
|
Hematopoietic | 1.05 | 0.833 – 1.31 | 0.675 | 85 | 850 | exclusion | phecode |
| 286.7 | Other and unspecified coagulation defects | Hematopoietic | 1.01 | 0.907 – 1.12 | 0.853 | 387 | 3870 | exclusion | phecode |
| 287 | Purpura and other hemorrhagic conditions | Hematopoietic | 1 | 0.954 – 1.06 | 0.851 | 1684 | 16840 | exclusion | phecode |
| 287.2 | Allergic purpura | Hematopoietic | 0.903 | 0.667 – 1.21 | 0.496 | 51 | 510 | exclusion | phecode |
| 287.3 | Thrombocytopenia | Hematopoietic | 0.999 | 0.946 – 1.05 | 0.971 | 1566 | 15660 | exclusion | phecode |
| 287.31 | Primary thrombocytopenia | Hematopoietic | 1.01 | 0.91 – 1.12 | 0.844 | 421 | 4210 | exclusion | phecode |
| 287.32 | Secondary thrombocytopenia | Hematopoietic | 1.06 | 0.828 – 1.34 | 0.648 | 75 | 750 | exclusion | phecode |
| 288 | Diseases of white blood cells | Hematopoietic | 1.01 | 0.979 – 1.05 | 0.457 | 3795 | 37950 | exclusion | phecode |
| 288.1 | Decreased white blood cell count | Hematopoietic | 1 | 0.965 – 1.04 | 0.901 | 3192 | 31920 | exclusion | phecode |
| 288.11 | Neutropenia | Hematopoietic | 1 | 0.965 – 1.04 | 0.901 | 3192 | 31920 | exclusion | phecode |
| 288.3 | Eosinophilia | Hematopoietic | 1.07 | 0.833 – 1.37 | 0.577 | 71 | 710 | exclusion | phecode |
| 289 | Other diseases of blood and blood-forming organs | Hematopoietic | 1.1 | 1.02 – 1.18 | 0.0105 | 868 | 8680 | exclusion | phecode |
| 289.3 |
Personal history of diseases of blood andPersonal history of diseases of blood and blood-forming organs
|
Hematopoietic | 1.13 | 1 – 1.28 | 0.0458 | 291 | 2910 | exclusion | phecode |
| 289.9 | Abnormality of red blood cells | Hematopoietic | 1.04 | 0.827 – 1.29 | 0.755 | 90 | 900 | exclusion | phecode |
| 290 |
Delirium dementia and amnestic and otherDelirium dementia and amnestic and other cognitive disorders
|
Mental Disorders | 1.08 | 1.03 – 1.14 | 0.00122 | 1949 | 19490 | exclusion | phecode |
| 290.1 | Dementias | Mental Disorders | 1.09 | 1.02 – 1.16 | 0.016 | 1006 | 10060 | exclusion | phecode |
| 290.11 | Alzheimer's disease | Mental Disorders | 1.07 | 0.966 – 1.18 | 0.195 | 433 | 4330 | exclusion | phecode |
| 290.16 | Vascular dementia | Mental Disorders | 1.23 | 1.06 – 1.43 | 0.00642 | 201 | 2010 | exclusion | phecode |
| 290.2 | Delirium due to conditions classified elsewhere | Mental Disorders | 1.08 | 0.992 – 1.17 | 0.0766 | 651 | 6510 | exclusion | phecode |
| 291 |
Other specified nonpsychotic and/or transientOther specified nonpsychotic and/or transient mental disorders
|
Mental Disorders | 1.1 | 1.01 – 1.19 | 0.0274 | 638 | 6380 | exclusion | phecode |
| 291.1 |
Transient mental disorders due to conditionsTransient mental disorders due to conditions classified elsewhere
|
Mental Disorders | 0.937 | 0.771 – 1.13 | 0.507 | 121 | 1210 | exclusion | phecode |
| 291.4 |
Specific nonpsychotic mental disorders due toSpecific nonpsychotic mental disorders due to brain damage
|
Mental Disorders | 1.19 | 0.951 – 1.49 | 0.121 | 85 | 850 | exclusion | phecode |
| 291.8 | Alteration of consciousness | Mental Disorders | 1.12 | 1.01 – 1.24 | 0.0256 | 437 | 4370 | exclusion | phecode |
| 292 | Neurological disorders | Mental Disorders | 1.01 | 0.982 – 1.04 | 0.43 | 4645 | 46450 | exclusion | phecode |
| 292.1 | Aphasia/speech disturbance | Mental Disorders | 1.01 | 0.961 – 1.07 | 0.599 | 1507 | 15070 | exclusion | phecode |
| 292.2 | Mild cognitive impairment | Mental Disorders | 1.01 | 0.865 – 1.18 | 0.892 | 190 | 1900 | exclusion | phecode |
| 292.3 | Memory loss | Mental Disorders | 0.987 | 0.91 – 1.07 | 0.746 | 700 | 7000 | exclusion | phecode |
| 292.4 | Altered mental status | Mental Disorders | 0.988 | 0.944 – 1.03 | 0.614 | 2185 | 21850 | exclusion | phecode |
| 292.6 | Hallucinations | Mental Disorders | 1.09 | 0.962 – 1.22 | 0.178 | 308 | 3080 | exclusion | phecode |
| 293 | Symptoms involving head and neck | Mental Disorders | 1.03 | 0.982 – 1.08 | 0.229 | 2082 | 20820 | exclusion | phecode |
| 295 | Schizophrenia and other psychotic disorders | Mental Disorders | 0.971 | 0.903 – 1.04 | 0.427 | 851 | 8510 | exclusion | phecode |
| 295.1 | Schizophrenia | Mental Disorders | 0.979 | 0.897 – 1.07 | 0.642 | 572 | 5720 | exclusion | phecode |
| 295.2 | Paranoid disorders | Mental Disorders | 0.986 | 0.843 – 1.15 | 0.863 | 179 | 1790 | exclusion | phecode |
| 295.3 | Psychosis | Mental Disorders | 0.92 | 0.782 – 1.08 | 0.314 | 171 | 1710 | exclusion | phecode |
| 296 | Mood disorders | Mental Disorders | 1.02 | 1.01 – 1.04 | 0.013 | 12461 | 124609 | exclusion | phecode |
| 296.1 | Bipolar | Mental Disorders | 1.04 | 0.97 – 1.1 | 0.295 | 1058 | 10580 | exclusion | phecode |
| 296.2 | Depression | Mental Disorders | 1.02 | 1 – 1.04 | 0.0152 | 11805 | 118049 | exclusion | phecode |
| 296.22 | Major depressive disorder | Mental Disorders | 1.03 | 0.926 – 1.16 | 0.544 | 361 | 3610 | exclusion | phecode |
| 297 | Suicidal ideation or attempt | Mental Disorders | 0.967 | 0.862 – 1.08 | 0.57 | 343 | 3391 | exclusion | phecode |
| 297.2 | Suicide or self-inflicted injury | Mental Disorders | 0.958 | 0.85 – 1.08 | 0.48 | 319 | 3161 | exclusion | phecode |
| 300 | Anxiety disorders | Mental Disorders | 1.02 | 0.993 – 1.04 | 0.162 | 6904 | 69029 | exclusion | phecode |
| 300.1 | Anxiety disorder | Mental Disorders | 1.02 | 0.989 – 1.04 | 0.241 | 6341 | 63399 | exclusion | phecode |
| 300.11 | Generalized anxiety disorder | Mental Disorders | 1.02 | 0.855 – 1.21 | 0.837 | 150 | 1500 | exclusion | phecode |
| 300.12 | Agorophobia, social phobia, and panic disorder | Mental Disorders | 1.02 | 0.939 – 1.1 | 0.675 | 704 | 7040 | exclusion | phecode |
| 300.13 | Phobia | Mental Disorders | 0.981 | 0.892 – 1.08 | 0.694 | 497 | 4970 | exclusion | phecode |
| 300.3 | Obsessive-compulsive disorders | Mental Disorders | 1.1 | 0.924 – 1.31 | 0.273 | 140 | 1400 | exclusion | phecode |
| 300.4 | Dysthymic disorder | Mental Disorders | 1.28 | 0.969 – 1.7 | 0.0762 | 53 | 530 | exclusion | phecode |
| 300.8 | Acute reaction to stress | Mental Disorders | 1.13 | 0.937 – 1.35 | 0.197 | 125 | 1250 | exclusion | phecode |
| 300.9 | Posttraumatic stress disorder | Mental Disorders | 0.94 | 0.771 – 1.14 | 0.531 | 113 | 1130 | exclusion | phecode |
| 301 | Personality disorders | Mental Disorders | 1.11 | 0.99 – 1.24 | 0.0716 | 337 | 3366 | exclusion | phecode |
| 301.2 | Antisocial/borderline personality disorder | Mental Disorders | 1.05 | 0.869 – 1.27 | 0.593 | 119 | 1186 | exclusion | phecode |
| 302 | Sexual and gender identity disorders | Mental Disorders | 0.924 | 0.82 – 1.04 | 0.19 | 322 | 3220 | exclusion | phecode |
| 303 | Psychogenic and somatoform disorders | Mental Disorders | 1.08 | 0.981 – 1.19 | 0.116 | 489 | 4890 | exclusion | phecode |
| 303.3 | Psychogenic disorder | Mental Disorders | 1.11 | 0.996 – 1.24 | 0.0564 | 354 | 3540 | exclusion | phecode |
| 303.4 | Somatoform disorder | Mental Disorders | 0.986 | 0.814 – 1.19 | 0.884 | 124 | 1240 | exclusion | phecode |
| 304 | Adjustment reaction | Mental Disorders | 0.997 | 0.882 – 1.13 | 0.964 | 295 | 2950 | exclusion | phecode |
| 306 | Other mental disorder | Mental Disorders | 1.02 | 1.01 – 1.03 | 0.000967 | 28125 | 230574 | exclusion | phecode |
| 306.9 | Tension headache | Mental Disorders | 1.01 | 0.899 – 1.14 | 0.841 | 315 | 3150 | exclusion | phecode |
| 313 | Pervasive developmental disorders | Mental Disorders | 1.01 | 0.797 – 1.28 | 0.922 | 77 | 770 | exclusion | phecode |
| 313.3 | Autism | Mental Disorders | 1.07 | 0.81 – 1.42 | 0.607 | 54 | 540 | exclusion | phecode |
| 315 | Develomental delays and disorders | Mental Disorders | 0.963 | 0.859 – 1.08 | 0.516 | 353 | 3530 | exclusion | phecode |
| 315.2 | Speech and language disorder | Mental Disorders | 1.07 | 0.858 – 1.34 | 0.533 | 89 | 890 | exclusion | phecode |
| 316 | Substance addiction and disorders | Mental Disorders | 0.973 | 0.873 – 1.08 | 0.614 | 395 | 3950 | exclusion | phecode |
| 316.1 | Polyneuropathy due to drugs | Mental Disorders | 1.04 | 0.787 – 1.36 | 0.769 | 60 | 600 | exclusion | phecode |
| 317 | Alcohol-related disorders | Mental Disorders | 1.05 | 1.03 – 1.07 | 1.56e-06 | 12829 | 128124 | exclusion | phecode |
| 317.1 | Alcoholism | Mental Disorders | 1.04 | 1.02 – 1.07 | 0.000167 | 8924 | 89210 | exclusion | phecode |
| 317.11 | Alcoholic liver damage | Mental Disorders | 1.04 | 0.966 – 1.12 | 0.306 | 842 | 8420 | exclusion | phecode |
| 318 | Tobacco use disorder | Mental Disorders | 1.03 | 1.01 – 1.04 | 0.000652 | 19447 | 185990 | exclusion | phecode |
| 320 | Meningitis | Neurological | 0.971 | 0.878 – 1.07 | 0.57 | 448 | 4480 | exclusion | phecode |
| 323 | Encephalitis | Neurological | 0.992 | 0.885 – 1.11 | 0.89 | 353 | 3530 | exclusion | phecode |
| 323.2 | Acute (transverse) myelitis | Neurological | 0.794 | 0.613 – 1.02 | 0.0734 | 74 | 740 | exclusion | phecode |
| 324 | Other CNS infection and poliomyelitis | Neurological | 0.972 | 0.858 – 1.1 | 0.656 | 295 | 2950 | exclusion | phecode |
| 327 | Sleep disorders | Neurological | 1.04 | 0.977 – 1.11 | 0.215 | 1170 | 11700 | exclusion | phecode |
| 327.3 | Sleep apnea | Neurological | 1.1 | 0.992 – 1.22 | 0.0681 | 404 | 4040 | exclusion | phecode |
| 327.4 | Insomnia | Neurological | 1.01 | 0.852 – 1.2 | 0.902 | 165 | 1650 | exclusion | phecode |
| 327.41 | Organic or persistent insomnia | Neurological | 0.952 | 0.788 – 1.15 | 0.605 | 138 | 1380 | exclusion | phecode |
| 331 | Other cerebral degenerations | Neurological | 0.985 | 0.925 – 1.05 | 0.638 | 1146 | 11460 | exclusion | phecode |
| 331.1 | Hydrocephalus | Neurological | 0.956 | 0.869 – 1.05 | 0.355 | 502 | 5020 | exclusion | phecode |
| 331.9 | Cerebral degeneration, unspecified | Neurological | 1.01 | 0.913 – 1.12 | 0.817 | 429 | 4290 | exclusion | phecode |
| 332 | Parkinson's disease | Neurological | 1 | 0.941 – 1.07 | 0.904 | 1128 | 11280 | exclusion | phecode |
| 333 |
Extrapyramidal disease and abnormal movementExtrapyramidal disease and abnormal movement disorders
|
Neurological | 1.04 | 0.967 – 1.11 | 0.299 | 901 | 9010 | exclusion | phecode |
| 333.1 | Essential tremor | Neurological | 1.01 | 0.867 – 1.16 | 0.939 | 216 | 2160 | exclusion | phecode |
| 333.2 | Myoclonus | Neurological | 0.923 | 0.738 – 1.15 | 0.472 | 96 | 960 | exclusion | phecode |
| 333.4 | Torsion dystonia | Neurological | 1.07 | 0.933 – 1.22 | 0.344 | 253 | 2530 | exclusion | phecode |
| 334 | Degenerative disease of the spinal cord | Neurological | 1.02 | 0.967 – 1.07 | 0.534 | 1818 | 18180 | exclusion | phecode |
| 334.1 | Spinocerebellar disease | Neurological | 0.998 | 0.819 – 1.21 | 0.985 | 117 | 1170 | exclusion | phecode |
| 334.2 | Anterior horn cell disease | Neurological | 1.09 | 0.956 – 1.25 | 0.19 | 245 | 2450 | exclusion | phecode |
| 335 | Multiple sclerosis | Neurological | 0.968 | 0.914 – 1.03 | 0.272 | 1354 | 13540 | exclusion | phecode |
| 337 | Disorders of the autonomic nervous system | Neurological | 1.02 | 0.893 – 1.16 | 0.799 | 269 | 2690 | exclusion | phecode |
| 337.1 | Peripheral autonomic neuropathy | Neurological | 0.939 | 0.729 – 1.2 | 0.618 | 72 | 720 | exclusion | phecode |
| 338 | Pain | Neurological | 0.999 | 0.925 – 1.08 | 0.972 | 772 | 7720 | exclusion | phecode |
| 338.1 | Acute pain | Neurological | 0.968 | 0.869 – 1.08 | 0.558 | 395 | 3950 | exclusion | phecode |
| 338.2 | Chronic pain | Neurological | 1.02 | 0.916 – 1.14 | 0.705 | 383 | 3830 | exclusion | phecode |
| 339 | Other headache syndromes | Neurological | 1 | 0.979 – 1.03 | 0.831 | 7843 | 78413 | exclusion | phecode |
| 340 | Migraine | Neurological | 0.999 | 0.96 – 1.04 | 0.951 | 2867 | 28670 | exclusion | phecode |
| 340.1 | Migrain with aura | Neurological | 1.01 | 0.87 – 1.16 | 0.941 | 212 | 2120 | exclusion | phecode |
| 341 |
Other demyelinating diseases of central nervousOther demyelinating diseases of central nervous system
|
Neurological | 1.06 | 0.932 – 1.21 | 0.359 | 254 | 2540 | exclusion | phecode |
| 342 | Hemiplegia | Neurological | 1.02 | 0.963 – 1.07 | 0.547 | 1498 | 14980 | exclusion | phecode |
| 343 | Infantile cerebral palsy | Neurological | 1.03 | 0.866 – 1.22 | 0.731 | 145 | 1450 | exclusion | phecode |
| 344 | Other paralytic syndromes | Neurological | 1.03 | 0.952 – 1.12 | 0.428 | 661 | 6610 | exclusion | phecode |
| 345 | Epilepsy, recurrent seizures, convulsions | Neurological | 1.02 | 0.99 – 1.05 | 0.199 | 5083 | 50830 | exclusion | phecode |
| 345.1 | Epilepsy | Neurological | 1.01 | 0.943 – 1.09 | 0.736 | 898 | 8980 | exclusion | phecode |
| 345.11 | Generalized convulsive epilepsy | Neurological | 1.03 | 0.93 – 1.14 | 0.581 | 445 | 4450 | exclusion | phecode |
| 345.12 | Partial epilepsy | Neurological | 1 | 0.884 – 1.14 | 0.969 | 279 | 2790 | exclusion | phecode |
| 345.3 | Convulsions | Neurological | 1.06 | 1.01 – 1.11 | 0.0126 | 2235 | 22350 | exclusion | phecode |
| 348 | Other conditions of brain | Neurological | 1.04 | 0.963 – 1.12 | 0.323 | 791 | 7910 | exclusion | phecode |
| 348.2 | Cerebral edema and compression of brain | Neurological | 1.04 | 0.918 – 1.19 | 0.504 | 268 | 2680 | exclusion | phecode |
| 348.4 | Cerebral cysts | Neurological | 0.944 | 0.787 – 1.13 | 0.527 | 136 | 1360 | exclusion | phecode |
| 348.8 | Encephalopathy, not elsewhere classified | Neurological | 1.11 | 0.969 – 1.26 | 0.13 | 252 | 2520 | exclusion | phecode |
| 349 |
Other and unspecified disorders of the nervousOther and unspecified disorders of the nervous system
|
Neurological | 0.997 | 0.888 – 1.12 | 0.957 | 342 | 3420 | exclusion | phecode |
| 350 | Abnormal movement | Neurological | 1.04 | 0.995 – 1.08 | 0.0887 | 2691 | 26910 | exclusion | phecode |
| 350.1 | Abnormal involuntary movements | Neurological | 1.02 | 0.954 – 1.1 | 0.51 | 888 | 8880 | exclusion | phecode |
| 350.2 | Abnormality of gait | Neurological | 1.03 | 0.981 – 1.09 | 0.213 | 1599 | 15990 | exclusion | phecode |
| 350.3 | Lack of coordination | Neurological | 1.16 | 1.04 – 1.29 | 0.00913 | 364 | 3640 | exclusion | phecode |
| 351 | Other peripheral nerve disorders | Neurological | 1.01 | 0.992 – 1.03 | 0.255 | 12454 | 124540 | exclusion | phecode |
| 352 | Disorders of other cranial nerves | Neurological | 1 | 0.946 – 1.06 | 0.966 | 1391 | 13910 | exclusion | phecode |
| 352.1 | Trigeminal nerve disorders [CN5] | Neurological | 0.947 | 0.857 – 1.05 | 0.287 | 463 | 4630 | exclusion | phecode |
| 352.2 | Facial nerve disorders [CN7] | Neurological | 1.03 | 0.962 – 1.11 | 0.369 | 880 | 8800 | exclusion | phecode |
| 353 | Nerve root and plexus disorders | Neurological | 1.04 | 0.979 – 1.11 | 0.189 | 1137 | 11370 | exclusion | phecode |
| 353.1 | Nerve plexus lesions | Neurological | 0.944 | 0.772 – 1.15 | 0.571 | 114 | 1140 | exclusion | phecode |
| 353.2 | Nerve root lesions | Neurological | 1.17 | 0.884 – 1.55 | 0.259 | 57 | 570 | exclusion | phecode |
| 356 | Hereditary and idiopathic peripheral neuropathy | Neurological | 0.998 | 0.841 – 1.18 | 0.985 | 152 | 1520 | exclusion | phecode |
| 357 | Inflammatory and toxic neuropathy | Neurological | 0.924 | 0.871 – 0.978 | 0.00709 | 1367 | 13670 | exclusion | phecode |
| 358 | Myoneural disorders | Neurological | 1.16 | 1.01 – 1.34 | 0.0347 | 213 | 2130 | exclusion | phecode |
| 358.1 | Myasthenia gravis | Neurological | 1.2 | 1.03 – 1.39 | 0.0165 | 192 | 1920 | exclusion | phecode |
| 359 | Muscular dystrophies and other myopathies | Neurological | 1.09 | 0.985 – 1.2 | 0.0952 | 469 | 4690 | exclusion | phecode |
| 359.1 | Muscular dystrophies | Neurological | 1.1 | 0.909 – 1.32 | 0.327 | 122 | 1220 | exclusion | phecode |
| 359.2 | Myopathy | Neurological | 1.08 | 0.962 – 1.2 | 0.198 | 361 | 3610 | exclusion | phecode |
| 360 | Disorders of the globe | Sense Organs | 1.06 | 0.945 – 1.19 | 0.316 | 337 | 3370 | exclusion | phecode |
| 360.2 | Progressive myopia | Sense Organs | 1.11 | 0.973 – 1.26 | 0.118 | 251 | 2510 | exclusion | phecode |
| 361 | Retinal detachments and defects | Sense Organs | 1.02 | 0.981 – 1.06 | 0.356 | 3256 | 32560 | exclusion | phecode |
| 361.1 | Retinal detachment with retinal defect | Sense Organs | 1.02 | 0.967 – 1.08 | 0.427 | 1389 | 13890 | exclusion | phecode |
| 361.2 | Retinoschisis and retinal cysts | Sense Organs | 0.815 | 0.624 – 1.06 | 0.123 | 68 | 680 | exclusion | phecode |
| 362 | Other retinal disorders | Sense Organs | 0.99 | 0.957 – 1.02 | 0.566 | 3858 | 38580 | exclusion | phecode |
| 362.2 |
Degeneration of macula and posterior pole ofDegeneration of macula and posterior pole of retina
|
Sense Organs | 0.991 | 0.947 – 1.04 | 0.708 | 2184 | 21840 | exclusion | phecode |
| 362.29 | Macular degeneration (senile) of retina NOS | Sense Organs | 0.994 | 0.949 – 1.04 | 0.782 | 2181 | 21810 | exclusion | phecode |
| 362.3 | Other nondiabetic retinopathy | Sense Organs | 0.93 | 0.784 – 1.1 | 0.395 | 160 | 1600 | exclusion | phecode |
| 362.31 | Separation of retinal layers | Sense Organs | 0.859 | 0.691 – 1.06 | 0.163 | 99 | 990 | exclusion | phecode |
| 362.4 | Retinal vascular changes and abnomalities | Sense Organs | 0.961 | 0.893 – 1.03 | 0.281 | 847 | 8470 | exclusion | phecode |
| 362.6 | Peripheral retinal degenerations | Sense Organs | 0.998 | 0.851 – 1.17 | 0.983 | 183 | 1830 | exclusion | phecode |
| 362.7 | Hereditary retinal dystrophies | Sense Organs | 0.92 | 0.726 – 1.16 | 0.48 | 82 | 820 | exclusion | phecode |
| 362.8 | Retinal hemorrhage/ischemia | Sense Organs | 1.01 | 0.828 – 1.22 | 0.94 | 116 | 1160 | exclusion | phecode |
| 363 |
Chorioretinal inflammations, scars, and otherChorioretinal inflammations, scars, and other disorders of choroid
|
Sense Organs | 1.04 | 0.882 – 1.22 | 0.65 | 171 | 1710 | exclusion | phecode |
| 363.3 | Chorioretinal scars | Sense Organs | 1.1 | 0.853 – 1.42 | 0.444 | 69 | 690 | exclusion | phecode |
| 364 | Corneal opacity and other disorders of cornea | Sense Organs | 0.983 | 0.904 – 1.07 | 0.683 | 658 | 6580 | exclusion | phecode |
| 364.2 | Corneal edema | Sense Organs | 0.921 | 0.718 – 1.17 | 0.502 | 80 | 800 | exclusion | phecode |
| 364.4 | Corneal degenerations | Sense Organs | 1.04 | 0.9 – 1.2 | 0.573 | 208 | 2080 | exclusion | phecode |
| 364.41 | Keratoconus | Sense Organs | 1.03 | 0.824 – 1.29 | 0.775 | 87 | 870 | exclusion | phecode |
| 364.5 | Corneal dystrophy | Sense Organs | 1.07 | 0.926 – 1.24 | 0.341 | 211 | 2110 | exclusion | phecode |
| 364.9 | Cornea replaced by transplant | Sense Organs | 1.12 | 0.904 – 1.37 | 0.3 | 100 | 1000 | exclusion | phecode |
| 365 | Glaucoma | Sense Organs | 1.03 | 0.998 – 1.06 | 0.062 | 4430 | 44300 | exclusion | phecode |
| 365.1 | Open-angle glaucoma | Sense Organs | 1.07 | 1 – 1.14 | 0.0487 | 1029 | 10290 | exclusion | phecode |
| 365.11 | Primary open angle glaucoma | Sense Organs | 1.07 | 1 – 1.15 | 0.0385 | 1023 | 10230 | exclusion | phecode |
| 365.2 | Primary angle-closure glaucoma | Sense Organs | 0.985 | 0.909 – 1.07 | 0.719 | 700 | 7000 | exclusion | phecode |
| 366 | Cataract | Sense Organs | 1.01 | 0.994 – 1.02 | 0.223 | 19997 | 169205 | exclusion | phecode |
| 366.1 | Nonsenile Cataract | Sense Organs | 1.04 | 0.809 – 1.33 | 0.757 | 70 | 700 | exclusion | phecode |
| 366.2 | Senile cataract | Sense Organs | 1.01 | 0.987 – 1.03 | 0.401 | 8261 | 82116 | exclusion | phecode |
| 366.3 | Traumatic cataract | Sense Organs | 1.08 | 0.874 – 1.32 | 0.48 | 102 | 1020 | exclusion | phecode |
| 367 |
Disorders of refraction and accommodationDisorders of refraction and accommodation; blindness and low vision
|
Sense Organs | 1.02 | 0.974 – 1.06 | 0.443 | 2428 | 24280 | exclusion | phecode |
| 367.1 | Myopia | Sense Organs | 1.01 | 0.953 – 1.07 | 0.694 | 1255 | 12550 | exclusion | phecode |
| 367.2 | Astigmatism | Sense Organs | 1.14 | 0.978 – 1.33 | 0.088 | 190 | 1900 | exclusion | phecode |
| 367.8 | Hypermetropia | Sense Organs | 1.04 | 0.907 – 1.19 | 0.586 | 252 | 2520 | exclusion | phecode |
| 367.9 | Blindness and low vision | Sense Organs | 1.01 | 0.938 – 1.1 | 0.716 | 723 | 7230 | exclusion | phecode |
| 368 | Visual disturbances | Sense Organs | 1.02 | 0.982 – 1.06 | 0.29 | 2990 | 29900 | exclusion | phecode |
| 368.1 | Amblyopia | Sense Organs | 1.11 | 1.02 – 1.22 | 0.0194 | 535 | 5350 | exclusion | phecode |
| 368.2 | Diplopia and disorders of binocular vision | Sense Organs | 0.992 | 0.917 – 1.07 | 0.848 | 730 | 7300 | exclusion | phecode |
| 368.3 | Anisometropia | Sense Organs | 0.947 | 0.796 – 1.12 | 0.533 | 155 | 1550 | exclusion | phecode |
| 368.9 | Subjective visual disturbances | Sense Organs | 1.03 | 0.944 – 1.12 | 0.518 | 614 | 6140 | exclusion | phecode |
| 369 | Infection of the eye | Sense Organs | 1 | 0.916 – 1.1 | 0.948 | 560 | 5600 | exclusion | phecode |
| 369.2 | Eye infection, viral | Sense Organs | 1.03 | 0.855 – 1.25 | 0.729 | 126 | 1260 | exclusion | phecode |
| 369.5 | Conjunctivitis, infectious | Sense Organs | 1.13 | 0.974 – 1.3 | 0.104 | 213 | 2130 | exclusion | phecode |
| 370 | Keratitis | Sense Organs | 1.01 | 0.897 – 1.15 | 0.818 | 297 | 2970 | exclusion | phecode |
| 370.1 | Corneal ulcer | Sense Organs | 1.05 | 0.882 – 1.26 | 0.563 | 141 | 1410 | exclusion | phecode |
| 371 | Inflammation of the eye | Sense Organs | 0.973 | 0.937 – 1.01 | 0.156 | 3168 | 31680 | exclusion | phecode |
| 371.1 | Uveitis, noninfectious or NOS | Sense Organs | 0.955 | 0.866 – 1.05 | 0.348 | 486 | 4860 | exclusion | phecode |
| 371.3 | Inflammation of eyelids | Sense Organs | 0.984 | 0.942 – 1.03 | 0.464 | 2391 | 23910 | exclusion | phecode |
| 372 | Disorders of conjunctiva | Sense Organs | 0.924 | 0.854 – 0.999 | 0.0468 | 764 | 7640 | exclusion | phecode |
| 374 | Other disorders of eyelids | Sense Organs | 1.05 | 1.02 – 1.08 | 0.00126 | 5700 | 57000 | exclusion | phecode |
| 374.1 | Ectropion or entropion | Sense Organs | 1.09 | 1.02 – 1.17 | 0.00731 | 1066 | 10660 | exclusion | phecode |
| 374.3 | Ptosis of eyelid | Sense Organs | 1.04 | 0.991 – 1.09 | 0.111 | 1826 | 18260 | exclusion | phecode |
| 375 | Disorders of lacrimal system | Sense Organs | 1.05 | 1.01 – 1.1 | 0.0251 | 2213 | 22130 | exclusion | phecode |
| 375.2 | Epiphora | Sense Organs | 1.1 | 1.03 – 1.19 | 0.00622 | 899 | 8990 | exclusion | phecode |
| 376 | Disorders of the orbit | Sense Organs | 1.09 | 0.865 – 1.37 | 0.446 | 86 | 860 | exclusion | phecode |
| 377 | Disorders of optic nerve and visual pathways | Sense Organs | 1 | 0.896 – 1.12 | 0.985 | 370 | 3700 | exclusion | phecode |
| 377.1 | Optic atrophy | Sense Organs | 0.672 | 0.494 – 0.905 | 0.00864 | 58 | 580 | exclusion | phecode |
| 377.3 | Optic neuritis/neuropathy | Sense Organs | 0.925 | 0.763 – 1.12 | 0.42 | 125 | 1250 | exclusion | phecode |
| 378 |
Strabismus and other disorders of binocular eyeStrabismus and other disorders of binocular eye movements
|
Sense Organs | 1.03 | 0.97 – 1.08 | 0.367 | 1437 | 14370 | exclusion | phecode |
| 378.1 | Strabismus (not specified as paralytic) | Sense Organs | 1.02 | 0.955 – 1.1 | 0.514 | 915 | 9150 | exclusion | phecode |
| 378.2 | Nystagmus and other irregular eye movements | Sense Organs | 0.98 | 0.845 – 1.14 | 0.791 | 214 | 2140 | exclusion | phecode |
| 378.5 | Paralytic strabismus | Sense Organs | 1.04 | 0.918 – 1.18 | 0.52 | 276 | 2760 | exclusion | phecode |
| 379 | Other disorders of eye | Sense Organs | 0.998 | 0.964 – 1.03 | 0.916 | 3740 | 37400 | exclusion | phecode |
| 379.2 | Disorders of vitreous body | Sense Organs | 1.02 | 0.961 – 1.08 | 0.557 | 1368 | 13680 | exclusion | phecode |
| 379.3 | Aphakia and other disorders of lens | Sense Organs | 1.02 | 0.968 – 1.07 | 0.48 | 1810 | 18100 | exclusion | phecode |
| 379.4 | Anomalies of pupillary function | Sense Organs | 0.88 | 0.68 – 1.13 | 0.313 | 70 | 700 | exclusion | phecode |
| 379.5 | Disorders of iris and ciliary body | Sense Organs | 0.906 | 0.812 – 1.01 | 0.0716 | 401 | 4010 | exclusion | phecode |
| 380 | Disorders of external ear | Sense Organs | 0.985 | 0.904 – 1.07 | 0.738 | 643 | 6430 | exclusion | phecode |
| 381 | Otitis media and Eustachian tube disorders | Sense Organs | 1.02 | 0.972 – 1.06 | 0.462 | 2253 | 22530 | exclusion | phecode |
| 381.1 | Otitis media | Sense Organs | 1.01 | 0.96 – 1.06 | 0.714 | 1820 | 18200 | exclusion | phecode |
| 381.11 | Suppurative and unspecified otitis media | Sense Organs | 1.03 | 0.956 – 1.1 | 0.451 | 854 | 8540 | exclusion | phecode |
| 381.2 | Eustachian tube disorders | Sense Organs | 0.963 | 0.826 – 1.12 | 0.622 | 191 | 1910 | exclusion | phecode |
| 381.3 | Mastoiditis & related conditions | Sense Organs | 1.01 | 0.861 – 1.19 | 0.874 | 171 | 1710 | exclusion | phecode |
| 381.9 | Otorrhea | Sense Organs | 0.988 | 0.87 – 1.12 | 0.847 | 280 | 2800 | exclusion | phecode |
| 382 | Otalgia | Sense Organs | 0.975 | 0.864 – 1.1 | 0.676 | 309 | 3090 | exclusion | phecode |
| 383 | Otosclerosis | Sense Organs | 1.19 | 1.06 – 1.34 | 0.00323 | 309 | 3090 | exclusion | phecode |
| 384 | Other disorders of tympanic membrane | Sense Organs | 1 | 0.945 – 1.06 | 0.985 | 1362 | 13620 | exclusion | phecode |
| 384.4 | Perforation of tympanic membrane | Sense Organs | 0.998 | 0.934 – 1.07 | 0.949 | 1043 | 10430 | exclusion | phecode |
| 385 | Other disorders of middle ear and mastoid | Sense Organs | 1.03 | 0.961 – 1.11 | 0.365 | 827 | 8270 | exclusion | phecode |
| 385.3 | Cholesteatoma | Sense Organs | 1.07 | 0.984 – 1.17 | 0.109 | 607 | 6070 | exclusion | phecode |
| 385.5 |
Tympanosclerosis and middle ear disease relatedTympanosclerosis and middle ear disease related to otitis media
|
Sense Organs | 1.02 | 0.894 – 1.17 | 0.726 | 241 | 2410 | exclusion | phecode |
| 386 |
Vertiginous syndromes and other disorders ofVertiginous syndromes and other disorders of vestibular system
|
Sense Organs | 1.04 | 0.991 – 1.1 | 0.104 | 1765 | 17650 | exclusion | phecode |
| 386.1 | Meniere's disease | Sense Organs | 1.09 | 0.997 – 1.19 | 0.057 | 578 | 5780 | exclusion | phecode |
| 386.2 | Peripheral or central vertigo | Sense Organs | 1.02 | 0.917 – 1.14 | 0.69 | 379 | 3790 | exclusion | phecode |
| 386.3 | Labyrinthitis | Sense Organs | 1.02 | 0.946 – 1.1 | 0.592 | 767 | 7670 | exclusion | phecode |
| 386.9 |
Dizziness and giddiness (Light-headedness andDizziness and giddiness (Light-headedness and vertigo)
|
Sense Organs | 1.04 | 0.907 – 1.19 | 0.58 | 243 | 2430 | exclusion | phecode |
| 388 | Other disorders of ear | Sense Organs | 1.11 | 0.957 – 1.28 | 0.166 | 202 | 2020 | exclusion | phecode |
| 389 | Hearing loss | Sense Organs | 1.04 | 1.01 – 1.07 | 0.0207 | 4243 | 42430 | exclusion | phecode |
| 389.1 | Sensorineural hearing loss | Sense Organs | 0.975 | 0.883 – 1.08 | 0.615 | 456 | 4560 | exclusion | phecode |
| 389.2 | Conductive hearing loss | Sense Organs | 1.1 | 0.994 – 1.21 | 0.0632 | 450 | 4500 | exclusion | phecode |
| 389.4 | Tinnitus | Sense Organs | 0.972 | 0.884 – 1.07 | 0.547 | 512 | 5120 | exclusion | phecode |
| 394 | Rheumatic disease of the heart valves | Circulatory System | 1.01 | 0.977 – 1.04 | 0.669 | 4912 | 49120 | exclusion | phecode |
| 394.2 | Mitral valve disease | Circulatory System | 0.998 | 0.96 – 1.04 | 0.934 | 2992 | 29920 | exclusion | phecode |
| 394.3 | Aortic valve disease | Circulatory System | 1.03 | 0.971 – 1.09 | 0.322 | 1283 | 12830 | exclusion | phecode |
| 394.7 | Disease of tricuspid valve | Circulatory System | 1.02 | 0.956 – 1.09 | 0.539 | 1054 | 10540 | exclusion | phecode |
| 395 | Heart valve disorders | Circulatory System | 0.997 | 0.965 – 1.03 | 0.842 | 4249 | 42490 | exclusion | phecode |
| 395.1 | Nonrheumatic mitral valve disorders | Circulatory System | 0.996 | 0.957 – 1.04 | 0.833 | 2892 | 28920 | exclusion | phecode |
| 395.2 | Nonrheumatic aortic valve disorders | Circulatory System | 1.01 | 0.885 – 1.14 | 0.929 | 278 | 2780 | exclusion | phecode |
| 395.3 | Nonrheumatic tricuspid valve disorders | Circulatory System | 1.19 | 0.964 – 1.46 | 0.101 | 104 | 1040 | exclusion | phecode |
| 395.4 | Nonrheumatic pulmonary valve disorders | Circulatory System | 0.841 | 0.67 – 1.05 | 0.126 | 96 | 960 | exclusion | phecode |
| 395.6 | Heart valve replaced | Circulatory System | 1.01 | 0.956 – 1.07 | 0.695 | 1494 | 14940 | exclusion | phecode |
| 396 | Abnormal heart sounds | Circulatory System | 0.974 | 0.912 – 1.04 | 0.429 | 1049 | 10490 | exclusion | phecode |
| 401 | Hypertension | Circulatory System | 1.01 | 0.998 – 1.02 | 0.148 | 74203 | 267481 | exclusion | phecode |
| 401.1 | Essential hypertension | Circulatory System | 1.01 | 0.997 – 1.02 | 0.165 | 73892 | 266307 | exclusion | phecode |
| 401.2 | Hypertensive heart and/or renal disease | Circulatory System | 1.02 | 0.967 – 1.07 | 0.524 | 1910 | 19099 | exclusion | phecode |
| 401.21 | Hypertensive heart disease | Circulatory System | 1.01 | 0.909 – 1.13 | 0.804 | 370 | 3700 | exclusion | phecode |
| 401.22 | Hypertensive chronic kidney disease | Circulatory System | 1.02 | 0.968 – 1.08 | 0.417 | 1551 | 15510 | exclusion | phecode |
| 401.3 | Other hypertensive complications | Circulatory System | 0.939 | 0.779 – 1.13 | 0.506 | 144 | 1440 | exclusion | phecode |
| 402 |
Elevated blood pressure reading withoutElevated blood pressure reading without diagnosis of hypertension
|
Circulatory System | 1.02 | 0.964 – 1.08 | 0.516 | 1481 | 14810 | exclusion | phecode |
| 411 | Ischemic Heart Disease | Circulatory System | 1.01 | 0.994 – 1.02 | 0.284 | 31407 | 211307 | exclusion | phecode |
| 411.1 | Unstable angina (intermediate coronary syndrome) | Circulatory System | 1.03 | 0.998 – 1.06 | 0.0704 | 5161 | 51604 | exclusion | phecode |
| 411.2 | Myocardial infarction | Circulatory System | 1.01 | 0.99 – 1.03 | 0.338 | 11981 | 112940 | exclusion | phecode |
| 411.3 | Angina pectoris | Circulatory System | 1.02 | 1.01 – 1.04 | 0.00761 | 15926 | 144026 | exclusion | phecode |
| 411.4 | Coronary atherosclerosis | Circulatory System | 1.01 | 0.993 – 1.02 | 0.3 | 20207 | 154941 | exclusion | phecode |
| 411.41 | Aneurysm and dissection of heart | Circulatory System | 0.967 | 0.891 – 1.05 | 0.407 | 701 | 7010 | exclusion | phecode |
| 411.8 |
Other chronic ischemic heart diseaseOther chronic ischemic heart disease, unspecified
|
Circulatory System | 1.01 | 0.992 – 1.03 | 0.309 | 15331 | 132062 | exclusion | phecode |
| 411.9 |
Other acute and subacute forms of ischemicOther acute and subacute forms of ischemic heart disease
|
Circulatory System | 1.04 | 0.978 – 1.1 | 0.218 | 1218 | 12180 | exclusion | phecode |
| 414 | Other forms of chronic heart disease | Circulatory System | 0.992 | 0.943 – 1.04 | 0.737 | 1827 | 18270 | exclusion | phecode |
| 414.2 | ASCVD | Circulatory System | 0.889 | 0.688 – 1.14 | 0.354 | 72 | 720 | exclusion | phecode |
| 415 | Pulmonary heart disease | Circulatory System | 0.999 | 0.968 – 1.03 | 0.956 | 4531 | 45310 | exclusion | phecode |
| 415.1 | Acute pulmonary heart disease | Circulatory System | 0.968 | 0.751 – 1.24 | 0.799 | 75 | 750 | exclusion | phecode |
| 415.11 | Pulmonary embolism and infarction, acute | Circulatory System | 0.968 | 0.751 – 1.24 | 0.799 | 75 | 750 | exclusion | phecode |
| 415.2 | Chronic pulmonary heart disease | Circulatory System | 0.985 | 0.903 – 1.07 | 0.735 | 602 | 6020 | exclusion | phecode |
| 415.21 | Primary pulmonary hypertension | Circulatory System | 0.977 | 0.883 – 1.08 | 0.652 | 447 | 4470 | exclusion | phecode |
| 416 | Cardiomegaly | Circulatory System | 1.02 | 0.982 – 1.07 | 0.273 | 2686 | 26860 | exclusion | phecode |
| 418 | Nonspecific chest pain | Circulatory System | 1 | 0.992 – 1.02 | 0.526 | 28677 | 270690 | exclusion | phecode |
| 418.1 | Precordial pain | Circulatory System | 1.02 | 0.989 – 1.06 | 0.185 | 3567 | 35670 | exclusion | phecode |
| 420 | Carditis | Circulatory System | 1.06 | 1.01 – 1.1 | 0.0205 | 2146 | 21460 | exclusion | phecode |
| 420.1 | Myocarditis | Circulatory System | 0.89 | 0.733 – 1.08 | 0.233 | 127 | 1270 | exclusion | phecode |
| 420.2 | Pericarditis | Circulatory System | 1.05 | 0.994 – 1.11 | 0.0775 | 1346 | 13460 | exclusion | phecode |
| 420.21 | Acute pericarditis | Circulatory System | 1.12 | 0.979 – 1.29 | 0.095 | 224 | 2240 | exclusion | phecode |
| 420.22 | Chronic pericarditis | Circulatory System | 1 | 0.822 – 1.22 | 0.963 | 113 | 1130 | exclusion | phecode |
| 420.3 | Endocarditis | Circulatory System | 1.08 | 1 – 1.17 | 0.0433 | 719 | 7190 | exclusion | phecode |
| 425 | Cardiomyopathy | Circulatory System | 1.02 | 0.963 – 1.08 | 0.471 | 1277 | 12770 | exclusion | phecode |
| 425.1 | Primary/intrinsic cardiomyopathies | Circulatory System | 1.02 | 0.959 – 1.08 | 0.558 | 1238 | 12380 | exclusion | phecode |
| 425.11 | Hypertrophic obstructive cardiomyopathy | Circulatory System | 0.986 | 0.822 – 1.18 | 0.882 | 132 | 1320 | exclusion | phecode |
| 425.12 | Other hypertrophic cardiomyopathy | Circulatory System | 0.959 | 0.812 – 1.13 | 0.612 | 164 | 1640 | exclusion | phecode |
| 425.8 | Other cardiomyopathy | Circulatory System | 1.02 | 0.778 – 1.34 | 0.875 | 60 | 600 | exclusion | phecode |
| 426 | Cardiac conduction disorders | Circulatory System | 1.02 | 0.996 – 1.05 | 0.0911 | 6937 | 69370 | exclusion | phecode |
| 426.2 | Atrioventricular [AV] block | Circulatory System | 1.03 | 0.979 – 1.07 | 0.279 | 2126 | 21259 | exclusion | phecode |
| 426.21 | First degree AV block | Circulatory System | 1.05 | 0.978 – 1.12 | 0.184 | 989 | 9890 | exclusion | phecode |
| 426.23 | Second degree AV block | Circulatory System | 0.992 | 0.897 – 1.1 | 0.878 | 453 | 4530 | exclusion | phecode |
| 426.24 | Atrioventricular block, complete | Circulatory System | 1 | 0.919 – 1.1 | 0.939 | 588 | 5871 | exclusion | phecode |
| 426.25 | Other heart block | Circulatory System | 0.957 | 0.793 – 1.15 | 0.641 | 132 | 1320 | exclusion | phecode |
| 426.3 | Bundle branch block | Circulatory System | 1.03 | 0.988 – 1.06 | 0.182 | 3344 | 33440 | exclusion | phecode |
| 426.31 | Right bundle branch block | Circulatory System | 1.05 | 0.993 – 1.11 | 0.0891 | 1496 | 14960 | exclusion | phecode |
| 426.32 | Left bundle branch block | Circulatory System | 1.01 | 0.96 – 1.06 | 0.717 | 1753 | 17530 | exclusion | phecode |
| 426.4 | Anomalous atrioventricular excitation | Circulatory System | 0.944 | 0.82 – 1.08 | 0.411 | 233 | 2330 | exclusion | phecode |
| 426.8 | Other cardiac conduction disorders | Circulatory System | 0.878 | 0.656 – 1.17 | 0.366 | 60 | 600 | exclusion | phecode |
| 426.9 | Cardiac pacemaker/device in situ | Circulatory System | 1.02 | 0.977 – 1.06 | 0.367 | 2485 | 24848 | exclusion | phecode |
| 426.91 | Cardiac pacemaker in situ | Circulatory System | 1.02 | 0.975 – 1.07 | 0.395 | 2281 | 22806 | exclusion | phecode |
| 427 | Cardiac dysrhythmias | Circulatory System | 1.01 | 0.999 – 1.03 | 0.0659 | 24341 | 206836 | exclusion | phecode |
| 427.1 | Paroxysmal tachycardia, unspecified | Circulatory System | 1.01 | 0.972 – 1.05 | 0.647 | 3219 | 32190 | exclusion | phecode |
| 427.11 | Paroxysmal supraventricular tachycardia | Circulatory System | 1.01 | 0.966 – 1.05 | 0.689 | 2353 | 23530 | exclusion | phecode |
| 427.12 | Paroxysmal ventricular tachycardia | Circulatory System | 1.04 | 0.966 – 1.11 | 0.321 | 938 | 9380 | exclusion | phecode |
| 427.2 | Atrial fibrillation and flutter | Circulatory System | 1.01 | 0.996 – 1.03 | 0.133 | 14669 | 133702 | exclusion | phecode |
| 427.3 | Other specified cardiac dysrhythmias | Circulatory System | 1.01 | 0.976 – 1.05 | 0.475 | 3234 | 32340 | exclusion | phecode |
| 427.4 | Cardiac arrest and ventricular fibrillation | Circulatory System | 1.06 | 0.995 – 1.12 | 0.073 | 1200 | 12000 | exclusion | phecode |
| 427.41 | Ventricular fibrillation and flutter | Circulatory System | 0.991 | 0.883 – 1.11 | 0.874 | 344 | 3440 | exclusion | phecode |
| 427.42 | Cardiac arrest | Circulatory System | 1.06 | 0.993 – 1.13 | 0.0794 | 991 | 9910 | exclusion | phecode |
| 427.5 | Arrhythmia (cardiac) NOS | Circulatory System | 0.962 | 0.897 – 1.03 | 0.278 | 957 | 9570 | exclusion | phecode |
| 427.6 | Premature beats | Circulatory System | 1.05 | 0.954 – 1.14 | 0.338 | 536 | 5360 | exclusion | phecode |
| 427.61 | Supraventricular premature beats | Circulatory System | 1.05 | 0.864 – 1.27 | 0.618 | 117 | 1169 | exclusion | phecode |
| 427.7 | Tachycardia NOS | Circulatory System | 1.01 | 0.969 – 1.06 | 0.535 | 2191 | 21899 | exclusion | phecode |
| 427.8 | Sinoatrial node dysfunction (Bradycardia) | Circulatory System | 1.08 | 0.972 – 1.2 | 0.151 | 403 | 4030 | exclusion | phecode |
| 427.9 | Palpitations | Circulatory System | 1.03 | 0.999 – 1.07 | 0.0574 | 3816 | 38155 | exclusion | phecode |
| 428 | Congestive heart failure; nonhypertensive | Circulatory System | 1.01 | 0.985 – 1.04 | 0.36 | 5621 | 56168 | exclusion | phecode |
| 428.1 | Congestive heart failure (CHF) NOS | Circulatory System | 1.03 | 0.988 – 1.08 | 0.146 | 2106 | 21052 | exclusion | phecode |
| 428.2 | Heart failure NOS | Circulatory System | 1 | 0.972 – 1.04 | 0.85 | 4457 | 44528 | exclusion | phecode |
| 429 |
Ill-defined descriptions and complications ofIll-defined descriptions and complications of heart disease
|
Circulatory System | 1.04 | 0.962 – 1.12 | 0.328 | 734 | 7340 | exclusion | phecode |
| 429.2 | Abnormal function study of cardiovascular system | Circulatory System | 1.03 | 0.942 – 1.13 | 0.49 | 524 | 5240 | exclusion | phecode |
| 429.3 | Symptoms involving cardiovascular system | Circulatory System | 1.06 | 0.909 – 1.23 | 0.47 | 198 | 1980 | exclusion | phecode |
| 430 | Intracranial hemorrhage | Circulatory System | 0.986 | 0.938 – 1.03 | 0.558 | 1908 | 19080 | exclusion | phecode |
| 430.1 | Subarachnoid hemorrhage | Circulatory System | 0.979 | 0.91 – 1.05 | 0.567 | 855 | 8550 | exclusion | phecode |
| 430.2 | Intracerebral hemorrhage | Circulatory System | 1.01 | 0.932 – 1.09 | 0.85 | 769 | 7690 | exclusion | phecode |
| 430.3 | Subdural hemorrhage | Circulatory System | 0.871 | 0.762 – 0.994 | 0.0412 | 267 | 2670 | exclusion | phecode |
| 433 | Cerebrovascular disease | Circulatory System | 1.02 | 0.996 – 1.04 | 0.0979 | 8804 | 87981 | exclusion | phecode |
| 433.1 | Occlusion and stenosis of precerebral arteries | Circulatory System | 1.04 | 0.977 – 1.1 | 0.217 | 1187 | 11848 | exclusion | phecode |
| 433.12 | Cerebral atherosclerosis | Circulatory System | 1.09 | 0.944 – 1.25 | 0.243 | 227 | 2270 | exclusion | phecode |
| 433.2 | Occlusion of cerebral arteries | Circulatory System | 1.04 | 1 – 1.07 | 0.0349 | 4244 | 42423 | exclusion | phecode |
| 433.21 |
Cerebral artery occlusion, with cerebralCerebral artery occlusion, with cerebral infarction
|
Circulatory System | 1.05 | 1 – 1.11 | 0.0433 | 1685 | 16840 | exclusion | phecode |
| 433.3 | Cerebral ischemia | Circulatory System | 0.995 | 0.956 – 1.03 | 0.799 | 2920 | 29192 | exclusion | phecode |
| 433.31 | Transient cerebral ischemia | Circulatory System | 1 | 0.955 – 1.05 | 0.993 | 2132 | 21312 | exclusion | phecode |
| 433.5 | Cerebral aneurysm | Circulatory System | 1 | 0.899 – 1.11 | 0.989 | 391 | 3909 | exclusion | phecode |
| 433.8 | Late effects of cerebrovascular disease | Circulatory System | 1.05 | 0.989 – 1.11 | 0.109 | 1270 | 12693 | exclusion | phecode |
| 440 | Atherosclerosis | Circulatory System | 1.01 | 0.949 – 1.06 | 0.859 | 1390 | 13890 | exclusion | phecode |
| 440.1 | Atherosclerosis of renal artery | Circulatory System | 0.946 | 0.765 – 1.16 | 0.596 | 113 | 1128 | exclusion | phecode |
| 440.2 | Atherosclerosis of the extremities | Circulatory System | 1 | 0.929 – 1.08 | 0.954 | 811 | 8105 | exclusion | phecode |
| 440.9 | Atherosclerosis of aorta | Circulatory System | 0.945 | 0.831 – 1.07 | 0.391 | 286 | 2860 | exclusion | phecode |
| 441 | Vascular insufficiency of intestine | Circulatory System | 1.07 | 0.98 – 1.16 | 0.131 | 620 | 6200 | exclusion | phecode |
| 441.1 | Acute vascular insufficiency of intestine | Circulatory System | 1 | 0.881 – 1.14 | 0.99 | 283 | 2830 | exclusion | phecode |
| 442 | Other aneurysm | Circulatory System | 1.03 | 0.978 – 1.08 | 0.278 | 1907 | 19057 | exclusion | phecode |
| 442.1 | Aortic aneurysm | Circulatory System | 1.04 | 0.981 – 1.1 | 0.2 | 1468 | 14679 | exclusion | phecode |
| 442.11 | Abdominal aortic aneurysm | Circulatory System | 1.03 | 0.957 – 1.1 | 0.469 | 939 | 9383 | exclusion | phecode |
| 442.2 | Aneurysm of iliac artery | Circulatory System | 1.02 | 0.823 – 1.26 | 0.848 | 102 | 1020 | exclusion | phecode |
| 442.3 | Aneurysm of artery of lower extremity | Circulatory System | 1.07 | 0.913 – 1.26 | 0.386 | 170 | 1700 | exclusion | phecode |
| 442.4 | Arterial dissection | Circulatory System | 0.991 | 0.747 – 1.31 | 0.95 | 55 | 550 | exclusion | phecode |
| 442.8 | Aneurysm of other specified artery | Circulatory System | 0.94 | 0.807 – 1.09 | 0.417 | 203 | 2030 | exclusion | phecode |
| 443 | Peripheral vascular disease | Circulatory System | 1.01 | 0.976 – 1.04 | 0.571 | 3950 | 39492 | exclusion | phecode |
| 443.1 | Raynaud's syndrome | Circulatory System | 1.03 | 0.963 – 1.09 | 0.43 | 1145 | 11450 | exclusion | phecode |
| 443.7 |
Peripheral angiopathy in diseases classifiedPeripheral angiopathy in diseases classified elsewhere
|
Circulatory System | 0.953 | 0.855 – 1.06 | 0.389 | 390 | 3900 | exclusion | phecode |
| 443.9 | Peripheral vascular disease, unspecified | Circulatory System | 1.01 | 0.969 – 1.05 | 0.628 | 2591 | 25902 | exclusion | phecode |
| 444 | Arterial embolism and thrombosis | Circulatory System | 1.01 | 0.945 – 1.09 | 0.715 | 930 | 9300 | exclusion | phecode |
| 444.1 |
Arterial embolism and thrombosis of lowerArterial embolism and thrombosis of lower extremity artery
|
Circulatory System | 0.966 | 0.882 – 1.06 | 0.459 | 556 | 5560 | exclusion | phecode |
| 446 | Polyarteritis nodosa and allied conditions | Circulatory System | 0.979 | 0.908 – 1.05 | 0.569 | 829 | 8290 | exclusion | phecode |
| 446.4 | Wegener's granulomatosis | Circulatory System | 0.871 | 0.738 – 1.02 | 0.0939 | 187 | 1870 | exclusion | phecode |
| 446.5 | Giant cell arteritis | Circulatory System | 1.04 | 0.933 – 1.16 | 0.471 | 386 | 3860 | exclusion | phecode |
| 446.9 | Arteritis NOS | Circulatory System | 0.944 | 0.821 – 1.08 | 0.414 | 240 | 2400 | exclusion | phecode |
| 447 | Other disorders of arteries and arterioles | Circulatory System | 1.03 | 0.967 – 1.09 | 0.4 | 1336 | 13360 | exclusion | phecode |
| 447.1 | Stricture of artery | Circulatory System | 1.05 | 0.981 – 1.13 | 0.149 | 873 | 8730 | exclusion | phecode |
| 448 | Disease of capillaries | Circulatory System | 1.07 | 0.894 – 1.28 | 0.451 | 142 | 1420 | exclusion | phecode |
| 450 | Noninfectious disorders of lymphatic channels | Circulatory System | 1.01 | 0.93 – 1.09 | 0.824 | 705 | 7050 | exclusion | phecode |
| 451 | Phlebitis and thrombophlebitis | Circulatory System | 1.03 | 1 – 1.07 | 0.0511 | 4020 | 40200 | exclusion | phecode |
| 451.2 |
Phlebitis and thrombophlebitis of lowerPhlebitis and thrombophlebitis of lower extremities
|
Circulatory System | 1.03 | 0.993 – 1.06 | 0.118 | 3707 | 37070 | exclusion | phecode |
| 452 | Other venous embolism and thrombosis | Circulatory System | 0.967 | 0.883 – 1.06 | 0.473 | 566 | 5660 | exclusion | phecode |
| 454 | Varicose veins | Circulatory System | 0.994 | 0.975 – 1.01 | 0.545 | 12019 | 120183 | exclusion | phecode |
| 454.1 | Varicose veins of lower extremity | Circulatory System | 0.993 | 0.973 – 1.01 | 0.469 | 11549 | 115483 | exclusion | phecode |
| 454.11 | Varicose veins of lower extremity, symptomtic | Circulatory System | 0.955 | 0.875 – 1.04 | 0.299 | 626 | 6257 | exclusion | phecode |
| 455 | Hemorrhoids | Circulatory System | 1.02 | 1.01 – 1.03 | 0.00427 | 23500 | 234947 | exclusion | phecode |
| 456 | Chronic venous insufficiency [CVI] | Circulatory System | 0.785 | 0.665 – 0.923 | 0.00354 | 188 | 1880 | exclusion | phecode |
| 457 |
Encounter for long-term (current) use ofEncounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
|
Circulatory System | 1.04 | 0.843 – 1.29 | 0.695 | 97 | 966 | exclusion | phecode |
| 458 | Hypotension | Circulatory System | 0.997 | 0.969 – 1.02 | 0.82 | 5801 | 58010 | exclusion | phecode |
| 458.1 | Orthostatic hypotension | Circulatory System | 0.99 | 0.934 – 1.05 | 0.734 | 1339 | 13390 | exclusion | phecode |
| 458.2 | Iatrogenic hypotension | Circulatory System | 1.08 | 0.942 – 1.24 | 0.257 | 234 | 2340 | exclusion | phecode |
| 458.9 | Hypotension NOS | Circulatory System | 0.987 | 0.952 – 1.02 | 0.488 | 3502 | 35020 | exclusion | phecode |
| 459 | Other disorders of circulatory system | Circulatory System | 1.02 | 1 – 1.04 | 0.0342 | 16386 | 161616 | exclusion | phecode |
| 459.1 | Hemorrhage NOS | Circulatory System | 0.982 | 0.819 – 1.17 | 0.842 | 142 | 1420 | exclusion | phecode |
| 459.9 | Circulatory disease NEC | Circulatory System | 1.02 | 1 – 1.04 | 0.0387 | 16173 | 159853 | exclusion | phecode |
| 464 | Acute sinusitis | Respiratory | 1.03 | 0.89 – 1.2 | 0.657 | 196 | 1960 | exclusion | phecode |
| 465 |
Acute upper respiratory infections of multipleAcute upper respiratory infections of multiple or unspecified sites
|
Respiratory | 1.01 | 0.964 – 1.05 | 0.746 | 2332 | 23320 | exclusion | phecode |
| 465.2 | Acute pharyngitis | Respiratory | 0.951 | 0.885 – 1.02 | 0.178 | 868 | 8680 | exclusion | phecode |
| 465.4 | Acute laryngitis and tracheitis | Respiratory | 1.03 | 0.873 – 1.21 | 0.72 | 166 | 1660 | exclusion | phecode |
| 470 | Septal Deviations/Turbinate Hypertrophy | Respiratory | 1.02 | 0.99 – 1.05 | 0.186 | 4909 | 49081 | exclusion | phecode |
| 471 | Nasal polyps | Respiratory | 1.03 | 0.991 – 1.07 | 0.136 | 3301 | 33009 | exclusion | phecode |
| 472 | Chronic pharyngitis and nasopharyngitis | Respiratory | 1.09 | 1.02 – 1.16 | 0.0145 | 963 | 9630 | exclusion | phecode |
| 473 | Diseases of the larynx and vocal cords | Respiratory | 1.04 | 0.997 – 1.08 | 0.0706 | 2623 | 26230 | exclusion | phecode |
| 473.1 | Chronic laryngitis | Respiratory | 0.95 | 0.767 – 1.17 | 0.63 | 104 | 1040 | exclusion | phecode |
| 473.3 | Paralysis/spasm of vocal cords or larynx | Respiratory | 0.994 | 0.872 – 1.13 | 0.925 | 265 | 2650 | exclusion | phecode |
| 473.4 | Voice disturbance | Respiratory | 1.08 | 1.01 – 1.15 | 0.0254 | 1083 | 10830 | exclusion | phecode |
| 474 | Acute and chronic tonsillitis | Respiratory | 0.993 | 0.947 – 1.04 | 0.773 | 2008 | 20072 | exclusion | phecode |
| 474.1 | Acute tonsillitis | Respiratory | 1.01 | 0.924 – 1.09 | 0.892 | 613 | 6130 | exclusion | phecode |
| 474.2 | Chronic tonsillitis and adenoiditis | Respiratory | 0.973 | 0.914 – 1.04 | 0.401 | 1124 | 11232 | exclusion | phecode |
| 475 | Chronic sinusitis | Respiratory | 1.01 | 0.972 – 1.06 | 0.532 | 2596 | 25951 | exclusion | phecode |
| 476 | Allergic rhinitis | Respiratory | 1 | 0.941 – 1.07 | 0.884 | 1059 | 10590 | exclusion | phecode |
| 477 | Epistaxis or throat hemorrhage | Respiratory | 0.991 | 0.949 – 1.03 | 0.672 | 2452 | 24509 | exclusion | phecode |
| 478 | Throat pain | Respiratory | 1.02 | 0.911 – 1.13 | 0.77 | 379 | 3790 | exclusion | phecode |
| 479 | Other upper respiratory disease | Respiratory | 1.02 | 0.988 – 1.06 | 0.219 | 4089 | 40884 | exclusion | phecode |
| 480 | Pneumonia | Respiratory | 1.01 | 0.988 – 1.03 | 0.414 | 10456 | 104475 | exclusion | phecode |
| 480.1 | Bacterial pneumonia | Respiratory | 1 | 0.976 – 1.03 | 0.901 | 6691 | 66910 | exclusion | phecode |
| 480.11 | Pneumococcal pneumonia | Respiratory | 1 | 0.975 – 1.03 | 0.867 | 5936 | 59360 | exclusion | phecode |
| 480.12 | Pseudomonal pneumonia | Respiratory | 0.964 | 0.771 – 1.2 | 0.739 | 93 | 930 | exclusion | phecode |
| 480.2 | Viral pneumonia | Respiratory | 1.13 | 0.881 – 1.44 | 0.323 | 73 | 730 | exclusion | phecode |
| 480.3 | Pneumonia due to fungus (mycoses) | Respiratory | 0.922 | 0.74 – 1.14 | 0.458 | 101 | 1010 | exclusion | phecode |
| 480.5 | Bronchopneumonia and lung abscess | Respiratory | 0.969 | 0.898 – 1.04 | 0.412 | 802 | 8020 | exclusion | phecode |
| 481 | Influenza | Respiratory | 0.981 | 0.872 – 1.1 | 0.753 | 331 | 3310 | exclusion | phecode |
| 483 | Acute bronchitis and bronchiolitis | Respiratory | 1.09 | 0.939 – 1.27 | 0.249 | 194 | 1940 | exclusion | phecode |
| 495 | Asthma | Respiratory | 1.02 | 1 – 1.03 | 0.0245 | 25799 | 251156 | exclusion | phecode |
| 495.2 | Asthma with exacerbation | Respiratory | 1.02 | 0.89 – 1.16 | 0.784 | 252 | 2520 | exclusion | phecode |
| 496 | Chronic airway obstruction | Respiratory | 1.03 | 1.01 – 1.06 | 0.00187 | 10487 | 102024 | exclusion | phecode |
| 496.1 | Emphysema | Respiratory | 1.03 | 0.98 – 1.08 | 0.23 | 1754 | 17540 | exclusion | phecode |
| 496.2 | Chronic bronchitis | Respiratory | 1.03 | 0.989 – 1.07 | 0.162 | 2965 | 29592 | exclusion | phecode |
| 496.21 | Obstructive chronic bronchitis | Respiratory | 1.02 | 0.982 – 1.07 | 0.268 | 2722 | 27164 | exclusion | phecode |
| 496.3 | Bronchiectasis | Respiratory | 1.01 | 0.96 – 1.06 | 0.749 | 1893 | 18930 | exclusion | phecode |
| 497 | Bronchitis | Respiratory | 0.941 | 0.864 – 1.02 | 0.16 | 634 | 6332 | exclusion | phecode |
| 500 | Lung disease due to external agents | Respiratory | 1 | 0.901 – 1.11 | 0.969 | 413 | 4113 | exclusion | phecode |
| 500.1 | Extrinsic allergic alveolitis | Respiratory | 1.09 | 0.854 – 1.38 | 0.483 | 79 | 790 | exclusion | phecode |
| 500.2 | Pneumoconiosis | Respiratory | 0.986 | 0.857 – 1.13 | 0.837 | 244 | 2423 | exclusion | phecode |
| 501 | Pneumonitis due to inhalation of food or vomitus | Respiratory | 1.1 | 1.01 – 1.19 | 0.0247 | 657 | 6570 | exclusion | phecode |
| 502 | Postinflammatory pulmonary fibrosis | Respiratory | 0.956 | 0.891 – 1.03 | 0.211 | 924 | 9240 | exclusion | phecode |
| 503 | Pulmonary congestion and hypostasis | Respiratory | 1.01 | 0.92 – 1.11 | 0.833 | 515 | 5150 | exclusion | phecode |
| 504 | Other alveolar and parietoalveolar pneumonopathy | Respiratory | 1.04 | 0.926 – 1.17 | 0.51 | 330 | 3300 | exclusion | phecode |
| 505 | Other pulmonary inflamation or edema | Respiratory | 0.918 | 0.697 – 1.2 | 0.533 | 61 | 610 | exclusion | phecode |
| 506 | Empyema and pneumothorax | Respiratory | 0.997 | 0.937 – 1.06 | 0.917 | 1181 | 11803 | exclusion | phecode |
| 507 | Pleurisy; pleural effusion | Respiratory | 1 | 0.977 – 1.03 | 0.807 | 6440 | 64382 | exclusion | phecode |
| 508 |
Pulmonary collapse; interstitial andPulmonary collapse; interstitial and compensatory emphysema
|
Respiratory | 1.02 | 0.968 – 1.06 | 0.521 | 2002 | 20020 | exclusion | phecode |
| 509 | Respiratory failure, insufficiency, arrest | Respiratory | 1.04 | 0.999 – 1.08 | 0.0574 | 2648 | 26474 | exclusion | phecode |
| 509.1 | Respiratory failure | Respiratory | 1.06 | 1.01 – 1.11 | 0.0116 | 2079 | 20784 | exclusion | phecode |
| 509.2 | Respiratory insufficiency | Respiratory | 1.05 | 0.995 – 1.1 | 0.0742 | 1819 | 18184 | exclusion | phecode |
| 509.5 | Respiratory arrest | Respiratory | 0.951 | 0.795 – 1.13 | 0.575 | 144 | 1440 | exclusion | phecode |
| 509.8 |
Dependence on respirator [Ventilator] orDependence on respirator [Ventilator] or supplemental oxygen
|
Respiratory | 1.01 | 0.903 – 1.12 | 0.904 | 389 | 3890 | exclusion | phecode |
| 510 | Other diseases of lung | Respiratory | 1.06 | 0.982 – 1.14 | 0.135 | 757 | 7570 | exclusion | phecode |
| 512 | Other symptoms of respiratory system | Respiratory | 1.03 | 1.01 – 1.05 | 0.0142 | 9079 | 90783 | exclusion | phecode |
| 512.1 | Wheezing | Respiratory | 1.01 | 0.873 – 1.16 | 0.905 | 220 | 2200 | exclusion | phecode |
| 512.2 | Painful respiration | Respiratory | 0.986 | 0.851 – 1.14 | 0.851 | 208 | 2080 | exclusion | phecode |
| 512.7 | Shortness of breath | Respiratory | 1.03 | 1 – 1.06 | 0.0483 | 5855 | 58547 | exclusion | phecode |
| 512.8 | Cough | Respiratory | 1.04 | 0.998 – 1.08 | 0.0639 | 2864 | 28636 | exclusion | phecode |
| 512.9 | Other dyspnea | Respiratory | 1.05 | 0.977 – 1.12 | 0.188 | 907 | 9070 | exclusion | phecode |
| 513 | Respiratory abnormalities | Respiratory | 1.06 | 0.972 – 1.15 | 0.189 | 614 | 6136 | exclusion | phecode |
| 513.3 | Hypoventilation | Respiratory | 0.909 | 0.712 – 1.15 | 0.43 | 83 | 830 | exclusion | phecode |
| 513.4 | Hyperventilation | Respiratory | 1.04 | 0.915 – 1.18 | 0.561 | 278 | 2780 | exclusion | phecode |
| 513.8 | Disorders of diaphragm | Respiratory | 1.06 | 0.893 – 1.25 | 0.501 | 154 | 1540 | exclusion | phecode |
| 514 | Abnormal findings examination of lungs | Respiratory | 1.04 | 0.997 – 1.09 | 0.0647 | 2473 | 24719 | exclusion | phecode |
| 516 | Abnormal sputum | Respiratory | 0.983 | 0.939 – 1.03 | 0.466 | 2172 | 21713 | exclusion | phecode |
| 516.1 | Hemoptysis | Respiratory | 0.996 | 0.951 – 1.04 | 0.879 | 2079 | 20781 | exclusion | phecode |
| 519 |
Other diseases of respiratory system, notOther diseases of respiratory system, not elsewhere classified
|
Respiratory | 1.02 | 1 – 1.04 | 0.0471 | 9497 | 94944 | exclusion | phecode |
| 519.2 | Respiratory complications | Respiratory | 1.11 | 0.984 – 1.24 | 0.0877 | 328 | 3280 | exclusion | phecode |
| 519.8 | Other diseases of respiratory system, NEC | Respiratory | 1.02 | 1 – 1.05 | 0.05 | 8881 | 88784 | exclusion | phecode |
| 519.9 |
Symptoms involving respiratory system and otherSymptoms involving respiratory system and other chest symptoms
|
Respiratory | 0.941 | 0.831 – 1.06 | 0.332 | 305 | 3050 | exclusion | phecode |
| 520 | Disorders of tooth development | Digestive | 1.04 | 0.995 – 1.08 | 0.0865 | 2446 | 24460 | exclusion | phecode |
| 520.1 | Hereditary disturbances in tooth structure | Digestive | 0.977 | 0.723 – 1.31 | 0.877 | 53 | 530 | exclusion | phecode |
| 520.2 | Disturbances in tooth eruption | Digestive | 1.04 | 0.994 – 1.08 | 0.0895 | 2361 | 23610 | exclusion | phecode |
| 521 | Diseases of hard tissues of teeth | Digestive | 1.01 | 0.971 – 1.05 | 0.652 | 3087 | 30870 | exclusion | phecode |
| 521.1 | Dental caries | Digestive | 1.01 | 0.971 – 1.05 | 0.64 | 3047 | 30470 | exclusion | phecode |
| 522 | Diseases of pulp and periapical tissues | Digestive | 0.996 | 0.948 – 1.05 | 0.878 | 1792 | 17917 | exclusion | phecode |
| 522.5 | Periapical abscess | Digestive | 0.994 | 0.934 – 1.06 | 0.841 | 1175 | 11750 | exclusion | phecode |
| 523 | Gingival and periodontal diseases | Digestive | 1.01 | 0.961 – 1.06 | 0.682 | 1741 | 17410 | exclusion | phecode |
| 523.1 | Gingivitis | Digestive | 0.985 | 0.804 – 1.2 | 0.878 | 114 | 1140 | exclusion | phecode |
| 523.3 | Periodontitis (acute or chronic) | Digestive | 1.04 | 0.98 – 1.1 | 0.188 | 1222 | 12220 | exclusion | phecode |
| 523.31 | Acute periodontitis | Digestive | 1.07 | 0.988 – 1.16 | 0.0923 | 668 | 6680 | exclusion | phecode |
| 523.32 | Chronic periodontitis | Digestive | 1.01 | 0.921 – 1.1 | 0.883 | 561 | 5610 | exclusion | phecode |
| 524 | Dentofacial anomalies, including malocclusion | Digestive | 1.06 | 0.949 – 1.19 | 0.284 | 345 | 3450 | exclusion | phecode |
| 524.3 | Anomalies of tooth position/malocclusion | Digestive | 1.02 | 0.902 – 1.15 | 0.768 | 305 | 3050 | exclusion | phecode |
| 525 |
Other diseases of the teeth and supportingOther diseases of the teeth and supporting structures
|
Digestive | 1.01 | 0.969 – 1.05 | 0.645 | 2685 | 26850 | exclusion | phecode |
| 525.2 | Atrophy of edentulous alveolar ridge | Digestive | 1.04 | 0.816 – 1.33 | 0.725 | 72 | 720 | exclusion | phecode |
| 526 | Diseases of the jaws | Digestive | 0.987 | 0.922 – 1.06 | 0.704 | 959 | 9590 | exclusion | phecode |
| 526.1 | Cysts of the jaws | Digestive | 0.98 | 0.872 – 1.1 | 0.729 | 329 | 3290 | exclusion | phecode |
| 526.3 | Anomalies of jaw size/symmetry | Digestive | 0.975 | 0.743 – 1.27 | 0.848 | 61 | 610 | exclusion | phecode |
| 526.4 | Temporomandibular joint disorders | Digestive | 1.09 | 0.951 – 1.24 | 0.212 | 240 | 2400 | exclusion | phecode |
| 526.41 | Temporomandibular joint disorder, unspecified | Digestive | 1.08 | 0.939 – 1.24 | 0.278 | 233 | 2330 | exclusion | phecode |
| 526.5 | Inflammatory conditions of jaw | Digestive | 1.04 | 0.846 – 1.26 | 0.73 | 110 | 1100 | exclusion | phecode |
| 526.9 | Jaw disease NOS | Digestive | 0.884 | 0.766 – 1.02 | 0.0886 | 234 | 2340 | exclusion | phecode |
| 527 | Diseases of the salivary glands | Digestive | 0.947 | 0.874 – 1.03 | 0.183 | 710 | 7100 | exclusion | phecode |
| 527.1 | Hypertrophy of salivary gland | Digestive | 0.892 | 0.705 – 1.12 | 0.327 | 84 | 840 | exclusion | phecode |
| 527.2 | Sialoadenitis | Digestive | 0.919 | 0.821 – 1.03 | 0.136 | 366 | 3660 | exclusion | phecode |
| 527.7 | Disturbance of salivary secretion | Digestive | 1.15 | 0.883 – 1.5 | 0.286 | 63 | 630 | exclusion | phecode |
| 527.8 | Other specified diseases of the salivary glands | Digestive | 0.969 | 0.796 – 1.18 | 0.752 | 120 | 1200 | exclusion | phecode |
| 528 |
Diseases of the oral soft tissues, excludingDiseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
|
Digestive | 1.01 | 0.978 – 1.05 | 0.511 | 3927 | 39270 | exclusion | phecode |
| 528.1 | Stomatitis and mucositis | Digestive | 1.09 | 0.99 – 1.2 | 0.0784 | 469 | 4690 | exclusion | phecode |
| 528.11 | Stomatitis and mucositis (ulcerative) | Digestive | 1.12 | 1.01 – 1.25 | 0.0357 | 390 | 3900 | exclusion | phecode |
| 528.12 | Oral aphthae | Digestive | 0.91 | 0.715 – 1.15 | 0.432 | 84 | 840 | exclusion | phecode |
| 528.3 | Cellulitis and abscess of oral soft tissues | Digestive | 1.03 | 0.884 – 1.21 | 0.67 | 181 | 1810 | exclusion | phecode |
| 528.4 | Cysts of oral soft tissues | Digestive | 0.803 | 0.661 – 0.972 | 0.0242 | 125 | 1250 | exclusion | phecode |
| 528.41 | Cyst of the salivary gland | Digestive | 0.787 | 0.629 – 0.98 | 0.0326 | 94 | 940 | exclusion | phecode |
| 528.5 | Diseases of lips | Digestive | 1.02 | 0.941 – 1.11 | 0.601 | 682 | 6820 | exclusion | phecode |
| 528.6 | Leukoplakia of oral mucosa | Digestive | 1.06 | 0.936 – 1.19 | 0.37 | 308 | 3080 | exclusion | phecode |
| 528.7 | Sialolithiasis | Digestive | 1.04 | 0.924 – 1.17 | 0.505 | 314 | 3140 | exclusion | phecode |
| 529 | Diseases and other conditions of the tongue | Digestive | 0.998 | 0.939 – 1.06 | 0.953 | 1235 | 12344 | exclusion | phecode |
| 529.1 | Glossitis | Digestive | 0.991 | 0.876 – 1.12 | 0.879 | 299 | 2990 | exclusion | phecode |
| 530 | Diseases of esophagus | Digestive | 1.02 | 1.01 – 1.04 | 0.000114 | 33704 | 280049 | exclusion | phecode |
| 530.1 | Esophagitis, GERD and related diseases | Digestive | 1.02 | 1.01 – 1.04 | 0.000223 | 31312 | 260239 | exclusion | phecode |
| 530.11 | GERD | Digestive | 1.02 | 0.997 – 1.03 | 0.0923 | 14058 | 140580 | exclusion | phecode |
| 530.12 | Ulcer of esophagus | Digestive | 1.05 | 1.02 – 1.09 | 0.00039 | 5219 | 52184 | exclusion | phecode |
| 530.14 | Reflux esophagitis | Digestive | 1.01 | 0.989 – 1.03 | 0.38 | 10473 | 104727 | exclusion | phecode |
| 530.2 | Esophageal bleeding (varices/hemorrhage) | Digestive | 1.04 | 0.986 – 1.09 | 0.157 | 1683 | 16830 | exclusion | phecode |
| 530.3 | Stricture and stenosis of esophagus | Digestive | 0.974 | 0.927 – 1.02 | 0.296 | 1873 | 18730 | exclusion | phecode |
| 530.5 | Disorders of esophageal motility | Digestive | 1.03 | 0.949 – 1.12 | 0.454 | 638 | 6380 | exclusion | phecode |
| 530.6 | Diverticulum of esophagus, acquired | Digestive | 1.11 | 0.931 – 1.31 | 0.248 | 153 | 1529 | exclusion | phecode |
| 530.7 | Gastroesophageal laceration-hemorrhage syndrome | Digestive | 1.05 | 0.938 – 1.18 | 0.384 | 344 | 3440 | exclusion | phecode |
| 530.9 | Heartburn | Digestive | 1.07 | 1.02 – 1.12 | 0.004 | 2096 | 20960 | exclusion | phecode |
| 531 | Peptic ulcer (excl. esophageal) | Digestive | 1 | 0.978 – 1.03 | 0.826 | 7421 | 74192 | exclusion | phecode |
| 531.1 | Hemorrhage from gastrointestinal ulcer | Digestive | 1.04 | 0.957 – 1.13 | 0.342 | 634 | 6340 | exclusion | phecode |
| 531.2 | Gastric ulcer | Digestive | 0.998 | 0.965 – 1.03 | 0.891 | 4099 | 40979 | exclusion | phecode |
| 531.3 | Duodenal ulcer | Digestive | 0.992 | 0.954 – 1.03 | 0.696 | 2994 | 29933 | exclusion | phecode |
| 531.4 | Peptic ulcer, site unspecified | Digestive | 1.1 | 0.989 – 1.22 | 0.077 | 424 | 4240 | exclusion | phecode |
| 532 | Dysphagia | Digestive | 1.05 | 1.02 – 1.08 | 0.000401 | 6447 | 64466 | exclusion | phecode |
| 535 | Gastritis and duodenitis | Digestive | 1.03 | 1.02 – 1.04 | 1.67e-05 | 28309 | 262547 | exclusion | phecode |
| 535.1 | Acute gastritis | Digestive | 1.03 | 0.964 – 1.09 | 0.427 | 1185 | 11850 | exclusion | phecode |
| 535.2 | Atrophic gastritis | Digestive | 1.13 | 1.02 – 1.26 | 0.025 | 370 | 3690 | exclusion | phecode |
| 535.6 | Duodenitis | Digestive | 1.04 | 1.01 – 1.06 | 0.00462 | 7605 | 76045 | exclusion | phecode |
| 535.8 | Other specified gastritis | Digestive | 1.03 | 1 – 1.05 | 0.0184 | 8094 | 80940 | exclusion | phecode |
| 535.9 | Gastritis and duodenitis, NOS | Digestive | 1.11 | 0.912 – 1.34 | 0.301 | 120 | 1192 | exclusion | phecode |
| 536 | Disorders of function of stomach | Digestive | 1.02 | 0.895 – 1.16 | 0.774 | 268 | 2666 | exclusion | phecode |
| 536.8 |
Dyspepsia and other specified disorders ofDyspepsia and other specified disorders of function of stomach
|
Digestive | 1.02 | 0.893 – 1.16 | 0.782 | 259 | 2576 | exclusion | phecode |
| 537 | Other disorders of stomach and duodenum | Digestive | 1.04 | 0.999 – 1.07 | 0.057 | 3400 | 33994 | exclusion | phecode |
| 540 | Appendiceal conditions | Digestive | 0.979 | 0.944 – 1.01 | 0.241 | 3409 | 34084 | exclusion | phecode |
| 540.1 | Appendicitis | Digestive | 0.978 | 0.942 – 1.01 | 0.234 | 3217 | 32164 | exclusion | phecode |
| 540.11 | Acute appendicitis | Digestive | 0.964 | 0.924 – 1 | 0.0788 | 2607 | 26064 | exclusion | phecode |
| 550 | Abdominal hernia | Digestive | 1.02 | 1.01 – 1.03 | 0.000178 | 45931 | 283394 | exclusion | phecode |
| 550.1 | Inguinal hernia | Digestive | 1.01 | 0.997 – 1.03 | 0.107 | 15818 | 123480 | exclusion | phecode |
| 550.2 | Diaphragmatic hernia | Digestive | 1.03 | 1.02 – 1.04 | 2.54e-05 | 26560 | 239425 | exclusion | phecode |
| 550.3 | Femoral hernia | Digestive | 1.02 | 0.943 – 1.11 | 0.571 | 651 | 6510 | exclusion | phecode |
| 550.4 | Umbilical hernia | Digestive | 1.01 | 0.974 – 1.04 | 0.656 | 3713 | 37130 | exclusion | phecode |
| 550.5 | Ventral hernia | Digestive | 1.03 | 0.996 – 1.07 | 0.0764 | 3441 | 34410 | exclusion | phecode |
| 555 |
Inflammatory bowel disease and otherInflammatory bowel disease and other gastroenteritis and colitis
|
Digestive | 1.01 | 0.975 – 1.04 | 0.683 | 4504 | 45040 | exclusion | phecode |
| 555.1 | Regional enteritis | Digestive | 0.974 | 0.925 – 1.02 | 0.308 | 1731 | 17310 | exclusion | phecode |
| 555.2 | Ulcerative colitis | Digestive | 1.03 | 0.989 – 1.07 | 0.171 | 3182 | 31820 | exclusion | phecode |
| 555.21 | Ulcerative colitis (chronic) | Digestive | 1 | 0.913 – 1.1 | 0.976 | 538 | 5380 | exclusion | phecode |
| 556 | Ulceration of the lower GI tract | Digestive | 1.09 | 1.02 – 1.16 | 0.0132 | 1062 | 10620 | exclusion | phecode |
| 556.1 | Ulceration of intestine | Digestive | 1.06 | 0.977 – 1.15 | 0.157 | 673 | 6730 | exclusion | phecode |
| 557 | Intestinal malabsorption (non-celiac) | Digestive | 0.937 | 0.828 – 1.06 | 0.293 | 301 | 3010 | exclusion | phecode |
| 558 | Noninfectious gastroenteritis | Digestive | 1.02 | 1 – 1.04 | 0.0223 | 15594 | 155922 | exclusion | phecode |
| 559 | Ileostomy status | Digestive | 1.01 | 0.956 – 1.06 | 0.786 | 1659 | 16590 | exclusion | phecode |
| 560 | Intestinal obstruction without mention of hernia | Digestive | 1.05 | 1.01 – 1.08 | 0.00749 | 4006 | 40053 | exclusion | phecode |
| 560.1 | Paralytic ileus | Digestive | 1.07 | 0.975 – 1.17 | 0.153 | 523 | 5230 | exclusion | phecode |
| 560.2 | Impaction of intestine | Digestive | 1.02 | 0.894 – 1.16 | 0.787 | 268 | 2680 | exclusion | phecode |
| 560.3 | Peritoneal or intestinal adhesions | Digestive | 1.1 | 1.02 – 1.18 | 0.0114 | 831 | 8310 | exclusion | phecode |
| 560.4 | Other intestinal obstruction | Digestive | 1.05 | 1.01 – 1.08 | 0.0176 | 3362 | 33616 | exclusion | phecode |
| 561 | Symptoms involving digestive system | Digestive | 1 | 0.984 – 1.02 | 0.948 | 15809 | 158086 | exclusion | phecode |
| 561.1 | Diarrhea | Digestive | 1.06 | 0.963 – 1.17 | 0.229 | 466 | 4660 | exclusion | phecode |
| 561.2 | Flatulence | Digestive | 0.996 | 0.945 – 1.05 | 0.867 | 1688 | 16880 | exclusion | phecode |
| 562 | Diverticulosis and diverticulitis | Digestive | 1.01 | 1 – 1.03 | 0.0267 | 26751 | 211994 | exclusion | phecode |
| 562.1 | Diverticulosis | Digestive | 1.01 | 1 – 1.03 | 0.0278 | 26709 | 211935 | exclusion | phecode |
| 563 | Constipation | Digestive | 1.01 | 0.985 – 1.03 | 0.563 | 10350 | 103421 | exclusion | phecode |
| 564 | Functional digestive disorders | Digestive | 1.02 | 1 – 1.03 | 0.018 | 21783 | 210993 | exclusion | phecode |
| 564.1 | Irritable Bowel Syndrome | Digestive | 1.01 | 0.986 – 1.04 | 0.325 | 5522 | 55220 | exclusion | phecode |
| 564.8 |
Abnormal findings on exam of gastrointestinalAbnormal findings on exam of gastrointestinal tract/ abdominal area
|
Digestive | 1 | 0.951 – 1.06 | 0.921 | 1649 | 16490 | exclusion | phecode |
| 564.9 | Personal history of diseases of digestive system | Digestive | 1.02 | 1 – 1.04 | 0.0137 | 15221 | 151974 | exclusion | phecode |
| 565 | Anal and rectal conditions | Digestive | 1.01 | 0.996 – 1.03 | 0.122 | 14862 | 148609 | exclusion | phecode |
| 565.1 | Anal and rectal polyp | Digestive | 1.02 | 0.991 – 1.04 | 0.2 | 7341 | 73408 | exclusion | phecode |
| 567 | Peritonitis and retroperitoneal infections | Digestive | 0.999 | 0.932 – 1.07 | 0.982 | 932 | 9320 | exclusion | phecode |
| 568 | Other disorders of peritoneum | Digestive | 1.02 | 0.983 – 1.06 | 0.291 | 3309 | 33090 | exclusion | phecode |
| 568.1 |
Peritoneal adhesions (postoperative)Peritoneal adhesions (postoperative) (postinfection)
|
Digestive | 1.02 | 0.981 – 1.06 | 0.325 | 3102 | 31020 | exclusion | phecode |
| 569 | Other disorders of intestine | Digestive | 1.01 | 0.973 – 1.04 | 0.726 | 4218 | 42180 | exclusion | phecode |
| 569.1 | Toxic gastroenteritis and colitis | Digestive | 1.12 | 0.942 – 1.33 | 0.19 | 149 | 1490 | exclusion | phecode |
| 569.2 | Gastrointestinal complications | Digestive | 0.986 | 0.895 – 1.09 | 0.771 | 484 | 4840 | exclusion | phecode |
| 571 | Chronic liver disease and cirrhosis | Digestive | 1.07 | 1.03 – 1.11 | 0.000387 | 2984 | 29840 | exclusion | phecode |
| 571.5 | Other chronic nonalcoholic liver disease | Digestive | 1.06 | 1.01 – 1.12 | 0.0249 | 1699 | 16990 | exclusion | phecode |
| 571.51 | Cirrhosis of liver without mention of alcohol | Digestive | 0.792 | 0.641 – 0.973 | 0.0266 | 115 | 1150 | exclusion | phecode |
| 571.6 | Primary biliary cirrhosis | Digestive | 1.13 | 0.986 – 1.28 | 0.0769 | 256 | 2560 | exclusion | phecode |
| 571.8 |
Liver abscess and sequelae of chronic liverLiver abscess and sequelae of chronic liver disease
|
Digestive | 1.07 | 1 – 1.14 | 0.0485 | 987 | 9870 | exclusion | phecode |
| 571.81 | Portal hypertension | Digestive | 1.08 | 0.981 – 1.18 | 0.119 | 532 | 5320 | exclusion | phecode |
| 572 | Ascites (non malignant) | Digestive | 0.991 | 0.938 – 1.05 | 0.738 | 1548 | 15480 | exclusion | phecode |
| 573 | Other disorders of liver | Digestive | 1 | 0.951 – 1.06 | 0.869 | 1505 | 15045 | exclusion | phecode |
| 573.5 | Jaundice (not of newborn) | Digestive | 0.858 | 0.643 – 1.14 | 0.283 | 59 | 590 | exclusion | phecode |
| 573.7 | Abnormal results of function study of liver | Digestive | 1.04 | 0.878 – 1.23 | 0.635 | 156 | 1555 | exclusion | phecode |
| 574 | Cholelithiasis and cholecystitis | Digestive | 1.03 | 1.01 – 1.04 | 0.00249 | 16011 | 160020 | exclusion | phecode |
| 574.1 | Cholelithiasis | Digestive | 1.02 | 1 – 1.04 | 0.0155 | 13618 | 136158 | exclusion | phecode |
| 574.11 | Cholelithiasis with acute cholecystitis | Digestive | 1.06 | 0.999 – 1.11 | 0.052 | 1511 | 15110 | exclusion | phecode |
| 574.12 | Cholelithiasis with other cholecystitis | Digestive | 1.02 | 0.99 – 1.05 | 0.195 | 5437 | 54370 | exclusion | phecode |
| 574.2 | Calculus of bile duct | Digestive | 0.996 | 0.955 – 1.04 | 0.843 | 2627 | 26264 | exclusion | phecode |
| 574.3 | Cholecystitis without cholelithiasis | Digestive | 1.03 | 0.993 – 1.08 | 0.107 | 2759 | 27590 | exclusion | phecode |
| 575 | Other biliary tract disease | Digestive | 1.02 | 0.989 – 1.06 | 0.192 | 3897 | 38970 | exclusion | phecode |
| 575.1 | Cholangitis | Digestive | 0.976 | 0.887 – 1.07 | 0.617 | 495 | 4950 | exclusion | phecode |
| 575.2 | Obstruction of bile duct | Digestive | 0.994 | 0.92 – 1.07 | 0.87 | 777 | 7770 | exclusion | phecode |
| 575.6 | Cholesterolosis of gallbladder | Digestive | 1.05 | 0.951 – 1.16 | 0.337 | 457 | 4570 | exclusion | phecode |
| 575.7 | Other disorders of gallbladder | Digestive | 1.07 | 1.01 – 1.13 | 0.0128 | 1410 | 14100 | exclusion | phecode |
| 575.8 | Other disorders of biliary tract | Digestive | 1.02 | 0.958 – 1.09 | 0.493 | 1037 | 10370 | exclusion | phecode |
| 575.9 |
Nonspecific abnormal findings on radiologicalNonspecific abnormal findings on radiological and other examination of biliary tract
|
Digestive | 0.969 | 0.863 – 1.09 | 0.585 | 349 | 3490 | exclusion | phecode |
| 577 | Diseases of pancreas | Digestive | 1.03 | 0.989 – 1.07 | 0.157 | 2702 | 27020 | exclusion | phecode |
| 577.1 | Acute pancreatitis | Digestive | 1.05 | 0.999 – 1.1 | 0.0557 | 1996 | 19960 | exclusion | phecode |
| 577.2 | Chronic pancreatitis | Digestive | 1.05 | 0.955 – 1.15 | 0.323 | 514 | 5140 | exclusion | phecode |
| 577.3 | Cyst and pseudocyst of pancreas | Digestive | 1.02 | 0.915 – 1.14 | 0.681 | 363 | 3630 | exclusion | phecode |
| 578 | Gastrointestinal hemorrhage | Digestive | 1.02 | 1.01 – 1.04 | 0.00572 | 20901 | 208958 | exclusion | phecode |
| 578.1 | Hematemesis | Digestive | 1.07 | 1.02 – 1.13 | 0.0029 | 1941 | 19396 | exclusion | phecode |
| 578.2 | Blood in stool | Digestive | 1.02 | 0.975 – 1.06 | 0.435 | 2597 | 25956 | exclusion | phecode |
| 578.8 | Hemorrhage of rectum and anus | Digestive | 1.03 | 1.01 – 1.05 | 0.0062 | 13031 | 130279 | exclusion | phecode |
| 578.9 | Hemorrhage of gastrointestinal tract | Digestive | 1.02 | 0.987 – 1.05 | 0.271 | 5292 | 52920 | exclusion | phecode |
| 579 | Other symptoms involving abdomen and pelvis | Digestive | 0.985 | 0.933 – 1.04 | 0.595 | 1553 | 15530 | exclusion | phecode |
| 579.2 | Splenomegaly | Digestive | 0.989 | 0.89 – 1.1 | 0.837 | 426 | 4260 | exclusion | phecode |
| 580 | Nephritis; nephrosis; renal sclerosis | Genitourinary | 1 | 0.949 – 1.06 | 0.94 | 1556 | 15560 | exclusion | phecode |
| 580.1 | Glomerulonephritis | Genitourinary | 0.993 | 0.93 – 1.06 | 0.841 | 1069 | 10690 | exclusion | phecode |
| 580.11 | Proliferative glomerulonephritis | Genitourinary | 1 | 0.785 – 1.28 | 0.984 | 79 | 790 | exclusion | phecode |
| 580.12 | Non-proliferative glomerulonephritis | Genitourinary | 0.924 | 0.762 – 1.11 | 0.407 | 136 | 1360 | exclusion | phecode |
| 580.14 | Chronic glomerulonephritis, NOS | Genitourinary | 0.998 | 0.928 – 1.07 | 0.961 | 881 | 8810 | exclusion | phecode |
| 580.2 |
Nephrotic syndrome without mention ofNephrotic syndrome without mention of glomerulonephritis
|
Genitourinary | 1.04 | 0.944 – 1.15 | 0.422 | 469 | 4690 | exclusion | phecode |
| 580.3 |
Nephritis and nephropathy without mention ofNephritis and nephropathy without mention of glomerulonephritis
|
Genitourinary | 0.97 | 0.845 – 1.11 | 0.657 | 253 | 2530 | exclusion | phecode |
| 580.32 |
Nephritis and nephropathy with pathologicalNephritis and nephropathy with pathological lesion
|
Genitourinary | 0.97 | 0.845 – 1.11 | 0.657 | 253 | 2530 | exclusion | phecode |
| 585 | Renal failure | Genitourinary | 0.995 | 0.969 – 1.02 | 0.68 | 7013 | 70119 | exclusion | phecode |
| 585.1 | Acute renal failure | Genitourinary | 0.975 | 0.944 – 1.01 | 0.117 | 4537 | 45366 | exclusion | phecode |
| 585.2 | Renal failure NOS | Genitourinary | 1.03 | 0.971 – 1.09 | 0.342 | 1466 | 14657 | exclusion | phecode |
| 585.3 | Chronic renal failure [CKD] | Genitourinary | 1 | 0.96 – 1.04 | 0.961 | 2652 | 26514 | exclusion | phecode |
| 585.31 | Renal dialysis | Genitourinary | 0.998 | 0.902 – 1.1 | 0.962 | 494 | 4940 | exclusion | phecode |
| 586 | Other disorders of the kidney and ureters | Genitourinary | 1.02 | 0.988 – 1.06 | 0.196 | 3382 | 33819 | exclusion | phecode |
| 586.1 | Anatomical abnormatilies of kidney and ureters | Genitourinary | 1.01 | 0.868 – 1.16 | 0.945 | 215 | 2150 | exclusion | phecode |
| 586.11 | Small kidney | Genitourinary | 0.979 | 0.834 – 1.15 | 0.798 | 180 | 1800 | exclusion | phecode |
| 586.2 | Cyst of kidney, acquired | Genitourinary | 0.999 | 0.941 – 1.06 | 0.976 | 1258 | 12579 | exclusion | phecode |
| 586.3 | Vascular disorders of kidney/hypertrophy | Genitourinary | 1.06 | 0.831 – 1.33 | 0.648 | 80 | 800 | exclusion | phecode |
| 586.4 | Stricture/obstruction of ureter | Genitourinary | 1.03 | 0.96 – 1.1 | 0.412 | 916 | 9160 | exclusion | phecode |
| 587 | Kidney replaced by transpant | Genitourinary | 1.01 | 0.892 – 1.13 | 0.913 | 369 | 3690 | exclusion | phecode |
| 588 | Disorders resulting from impaired renal function | Genitourinary | 1.04 | 0.838 – 1.29 | 0.705 | 99 | 990 | exclusion | phecode |
| 589 | Abnormal results of function study of kidney | Genitourinary | 0.871 | 0.708 – 1.07 | 0.182 | 117 | 1170 | exclusion | phecode |
| 590 | Pyelonephritis | Genitourinary | 0.996 | 0.94 – 1.06 | 0.901 | 1331 | 13310 | exclusion | phecode |
| 591 | Urinary tract infection | Genitourinary | 1 | 0.982 – 1.02 | 0.926 | 12432 | 124264 | exclusion | phecode |
| 592 | Cystitis and urethritis | Genitourinary | 1.01 | 0.976 – 1.05 | 0.467 | 3076 | 30754 | exclusion | phecode |
| 592.1 | Cystitis | Genitourinary | 1.01 | 0.976 – 1.06 | 0.467 | 2936 | 29354 | exclusion | phecode |
| 592.11 | Acute cystitis | Genitourinary | 1.06 | 0.877 – 1.27 | 0.556 | 137 | 1370 | exclusion | phecode |
| 592.12 | Chronic cystitis | Genitourinary | 0.975 | 0.907 – 1.05 | 0.492 | 889 | 8890 | exclusion | phecode |
| 592.13 | Chronic interstitial cystitis | Genitourinary | 1.02 | 0.892 – 1.16 | 0.77 | 247 | 2470 | exclusion | phecode |
| 592.2 | Urethritis and urethral syndrome | Genitourinary | 0.995 | 0.843 – 1.17 | 0.953 | 167 | 1670 | exclusion | phecode |
| 593 | Hematuria | Genitourinary | 1.02 | 1.01 – 1.04 | 0.00737 | 16202 | 161323 | exclusion | phecode |
| 594 | Urinary calculus | Genitourinary | 1.02 | 0.998 – 1.05 | 0.0752 | 6612 | 66119 | exclusion | phecode |
| 594.1 | Calculus of kidney | Genitourinary | 1.02 | 0.985 – 1.06 | 0.236 | 3176 | 31760 | exclusion | phecode |
| 594.2 | Calculus of lower urinary tract | Genitourinary | 1.04 | 0.961 – 1.12 | 0.335 | 776 | 7760 | exclusion | phecode |
| 594.3 | Calculus of ureter | Genitourinary | 1.03 | 0.984 – 1.07 | 0.225 | 2403 | 24029 | exclusion | phecode |
| 594.8 | Renal colic | Genitourinary | 1.02 | 0.97 – 1.06 | 0.495 | 2045 | 20449 | exclusion | phecode |
| 595 | Hydronephrosis | Genitourinary | 1.01 | 0.958 – 1.05 | 0.826 | 1953 | 19530 | exclusion | phecode |
| 596 | Other disorders of bladder | Genitourinary | 1.01 | 0.987 – 1.03 | 0.445 | 9856 | 98560 | exclusion | phecode |
| 596.1 | Bladder neck obstruction | Genitourinary | 1.01 | 0.965 – 1.06 | 0.619 | 1963 | 19630 | exclusion | phecode |
| 596.5 | Functional disorders of bladder | Genitourinary | 1.05 | 0.996 – 1.1 | 0.0724 | 1653 | 16530 | exclusion | phecode |
| 597 | Other disorders of urethra and urinary tract | Genitourinary | 1 | 0.97 – 1.04 | 0.868 | 3984 | 39834 | exclusion | phecode |
| 597.1 | Urethral stricture (not specified as infectious) | Genitourinary | 0.993 | 0.957 – 1.03 | 0.721 | 3322 | 33214 | exclusion | phecode |
| 598 | Abnormal findings on examination of urine | Genitourinary | 1.01 | 0.977 – 1.05 | 0.513 | 3538 | 35378 | exclusion | phecode |
| 598.9 |
Other nonspecific findings on examination ofOther nonspecific findings on examination of urine
|
Genitourinary | 1.13 | 1 – 1.27 | 0.0444 | 304 | 3040 | exclusion | phecode |
| 599 | Other symptoms/disorders or the urinary system | Genitourinary | 1.01 | 0.99 – 1.02 | 0.523 | 18729 | 187237 | exclusion | phecode |
| 599.1 | Urinary obstruction | Genitourinary | 0.961 | 0.813 – 1.13 | 0.633 | 167 | 1670 | exclusion | phecode |
| 599.2 | Retention of urine | Genitourinary | 0.993 | 0.968 – 1.02 | 0.606 | 6733 | 67330 | exclusion | phecode |
| 599.3 | Dysuria | Genitourinary | 1.02 | 0.963 – 1.09 | 0.455 | 1199 | 11990 | exclusion | phecode |
| 599.4 | Urinary incontinence | Genitourinary | 1.01 | 0.984 – 1.03 | 0.575 | 8766 | 87659 | exclusion | phecode |
| 599.5 | Frequency of urination and polyuria | Genitourinary | 0.988 | 0.956 – 1.02 | 0.495 | 4023 | 40230 | exclusion | phecode |
| 599.6 | Oliguria and anuria | Genitourinary | 1.21 | 0.984 – 1.49 | 0.0663 | 107 | 1070 | exclusion | phecode |
| 599.8 | Other symptoms involving urinary system | Genitourinary | 0.982 | 0.777 – 1.23 | 0.874 | 87 | 870 | exclusion | phecode |
| 599.9 | Other abnormality of urination | Genitourinary | 1.03 | 0.983 – 1.08 | 0.202 | 1921 | 19210 | exclusion | phecode |
| 600 | Hyperplasia of prostate | Genitourinary | 0.998 | 0.978 – 1.02 | 0.842 | 11123 | 87742 | exclusion | phecode |
| 601 | Inflammatory diseases of prostate | Genitourinary | 0.975 | 0.931 – 1.02 | 0.27 | 2188 | 21880 | exclusion | phecode |
| 601.1 | Prostatitis | Genitourinary | 0.982 | 0.93 – 1.04 | 0.501 | 1576 | 15760 | exclusion | phecode |
| 601.11 | Acute prostatitis | Genitourinary | 0.931 | 0.807 – 1.07 | 0.321 | 235 | 2350 | exclusion | phecode |
| 601.12 | Chronic prostatitis | Genitourinary | 0.986 | 0.918 – 1.06 | 0.696 | 910 | 9100 | exclusion | phecode |
| 601.3 | Orchitis and epididymitis | Genitourinary | 1.23 | 0.931 – 1.62 | 0.139 | 59 | 590 | exclusion | phecode |
| 601.4 | Balanoposthitis | Genitourinary | 0.91 | 0.802 – 1.03 | 0.142 | 286 | 2860 | exclusion | phecode |
| 601.8 |
Other inflammatory disorders of male genitalOther inflammatory disorders of male genital organs
|
Genitourinary | 0.952 | 0.841 – 1.08 | 0.434 | 303 | 3030 | exclusion | phecode |
| 602 | Other disorders of prostate | Genitourinary | 0.941 | 0.887 – 0.997 | 0.0407 | 1343 | 13430 | exclusion | phecode |
| 603 | Other disorders of testis | Genitourinary | 1 | 0.958 – 1.05 | 0.908 | 2192 | 21912 | exclusion | phecode |
| 603.1 | Hydrocele | Genitourinary | 0.975 | 0.919 – 1.03 | 0.39 | 1340 | 13400 | exclusion | phecode |
| 604 | Disorders of penis | Genitourinary | 0.959 | 0.925 – 0.995 | 0.0256 | 3412 | 34093 | exclusion | phecode |
| 604.1 | Redundant prepuce and phimosis/BXO | Genitourinary | 0.96 | 0.922 – 0.999 | 0.0425 | 2853 | 28505 | exclusion | phecode |
| 605 | Erectile dysfunction [ED] | Genitourinary | 1 | 0.883 – 1.14 | 0.951 | 280 | 2800 | exclusion | phecode |
| 608 | Other disorders of male genital organs | Genitourinary | 0.98 | 0.942 – 1.02 | 0.326 | 2826 | 28259 | exclusion | phecode |
| 609 | Male infertility and abnormal spermatozoa | Genitourinary | 0.894 | 0.773 – 1.03 | 0.128 | 233 | 2330 | exclusion | phecode |
| 609.1 | Infertility, male | Genitourinary | 0.845 | 0.644 – 1.1 | 0.212 | 64 | 640 | exclusion | phecode |
| 609.2 | Abnormal spermatozoa | Genitourinary | 0.912 | 0.768 – 1.08 | 0.289 | 170 | 1700 | exclusion | phecode |
| 610 | Benign mammary dysplasias | Genitourinary | 1.02 | 0.982 – 1.06 | 0.278 | 2838 | 28379 | exclusion | phecode |
| 610.1 | Cystic mastopathy | Genitourinary | 1.12 | 1.05 – 1.2 | 0.00109 | 923 | 9229 | exclusion | phecode |
| 610.2 | Fibroadenosis of breast | Genitourinary | 0.936 | 0.827 – 1.06 | 0.287 | 306 | 3060 | exclusion | phecode |
| 610.3 | Fibrosclerosis of breast | Genitourinary | 1.03 | 0.912 – 1.16 | 0.628 | 301 | 3010 | exclusion | phecode |
| 610.4 | Benign neoplasm of breast | Genitourinary | 0.995 | 0.943 – 1.05 | 0.849 | 1548 | 15479 | exclusion | phecode |
| 610.8 | Other specified benign mammary dysplasias | Genitourinary | 0.998 | 0.844 – 1.18 | 0.978 | 165 | 1650 | exclusion | phecode |
| 611 | Abnormal findings on mammogram or breast exam | Genitourinary | 1.03 | 0.972 – 1.08 | 0.357 | 1578 | 15780 | exclusion | phecode |
| 611.1 | Abnormal mammogram | Genitourinary | 1.08 | 0.819 – 1.43 | 0.561 | 57 | 570 | exclusion | phecode |
| 611.3 | Lump or mass in breast | Genitourinary | 1.02 | 0.967 – 1.08 | 0.445 | 1523 | 15230 | exclusion | phecode |
| 612 |
Breast conditions, congenital or relating toBreast conditions, congenital or relating to hormones
|
Genitourinary | 0.991 | 0.925 – 1.06 | 0.8 | 939 | 9390 | exclusion | phecode |
| 612.2 | Hypertrophy of breast (Gynecomastia) | Genitourinary | 0.996 | 0.927 – 1.07 | 0.922 | 851 | 8510 | exclusion | phecode |
| 612.3 | Congenital anomalies of breast | Genitourinary | 0.905 | 0.708 – 1.15 | 0.418 | 78 | 780 | exclusion | phecode |
| 613 | Other nonmalignant breast conditions | Genitourinary | 1.06 | 1.01 – 1.11 | 0.012 | 1981 | 19796 | exclusion | phecode |
| 613.1 | Inflammatory disease of breast | Genitourinary | 1.05 | 0.974 – 1.14 | 0.189 | 721 | 7205 | exclusion | phecode |
| 613.5 | Mastodynia | Genitourinary | 0.993 | 0.777 – 1.26 | 0.952 | 77 | 770 | exclusion | phecode |
| 613.7 | Other signs and symptoms in breast | Genitourinary | 1.09 | 1 – 1.17 | 0.0405 | 704 | 7031 | exclusion | phecode |
| 613.8 | Other specified disorders of breast | Genitourinary | 1.07 | 0.957 – 1.21 | 0.223 | 328 | 3280 | exclusion | phecode |
| 613.9 | Breast disorder NOS | Genitourinary | 1.07 | 0.923 – 1.24 | 0.355 | 207 | 2070 | exclusion | phecode |
| 614 | Inflammatory diseases of female pelvic organs | Genitourinary | 1.02 | 0.992 – 1.05 | 0.164 | 6180 | 61800 | exclusion | phecode |
| 614.1 |
Pelvic peritoneal adhesions, femalePelvic peritoneal adhesions, female (postoperative) (postinfection)
|
Genitourinary | 1.02 | 0.982 – 1.07 | 0.272 | 2538 | 25380 | exclusion | phecode |
| 614.3 | Pelvic inflammatory disease (PID) | Genitourinary | 1.04 | 0.967 – 1.11 | 0.314 | 934 | 9340 | exclusion | phecode |
| 614.31 | Acute inflammatory pelvic disease | Genitourinary | 1.23 | 0.944 – 1.59 | 0.12 | 61 | 610 | exclusion | phecode |
| 614.32 | Chronic inflammatory pelvic disease | Genitourinary | 1.04 | 0.934 – 1.15 | 0.505 | 422 | 4220 | exclusion | phecode |
| 614.33 | Pelvic inflammatory disease, NOS | Genitourinary | 1 | 0.898 – 1.12 | 0.934 | 352 | 3520 | exclusion | phecode |
| 614.4 | Inflammatory diseases of uterus, except cervix | Genitourinary | 0.942 | 0.829 – 1.07 | 0.359 | 278 | 2780 | exclusion | phecode |
| 614.5 |
Inflammatory disease of cervix, vagina, andInflammatory disease of cervix, vagina, and vulva
|
Genitourinary | 1.02 | 0.98 – 1.06 | 0.335 | 2850 | 28500 | exclusion | phecode |
| 614.51 | Cervicitis and endocervicitis | Genitourinary | 1.01 | 0.951 – 1.07 | 0.78 | 1317 | 13170 | exclusion | phecode |
| 614.52 | Vaginitis and vulvovaginitis | Genitourinary | 1.03 | 0.928 – 1.14 | 0.59 | 426 | 4260 | exclusion | phecode |
| 614.53 | Cyst or abscess of Bartholin's gland | Genitourinary | 0.991 | 0.917 – 1.07 | 0.817 | 754 | 7540 | exclusion | phecode |
| 614.54 | Abscess or ulceration of vulva | Genitourinary | 1.05 | 0.928 – 1.2 | 0.415 | 274 | 2740 | exclusion | phecode |
| 615 | Endometriosis | Genitourinary | 1.02 | 0.982 – 1.05 | 0.365 | 4035 | 40341 | exclusion | phecode |
| 617 |
Disorders secondary to childbirth, surgeryDisorders secondary to childbirth, surgery, trauma
|
Genitourinary | 1.07 | 0.945 – 1.2 | 0.288 | 305 | 3050 | exclusion | phecode |
| 618 | Genital prolapse | Genitourinary | 1 | 0.982 – 1.02 | 0.912 | 11829 | 118039 | exclusion | phecode |
| 618.1 | Prolapse of vaginal walls | Genitourinary | 1.01 | 0.99 – 1.04 | 0.235 | 7403 | 74030 | exclusion | phecode |
| 618.2 | Uterine/Uterovaginal prolapse | Genitourinary | 0.984 | 0.956 – 1.01 | 0.28 | 5397 | 53970 | exclusion | phecode |
| 618.5 | Prolapse of vaginal vault after hysterectomy | Genitourinary | 1.06 | 0.963 – 1.16 | 0.244 | 513 | 5130 | exclusion | phecode |
| 618.6 | Vaginal enterocele, congenital or acquired | Genitourinary | 1.03 | 0.948 – 1.11 | 0.505 | 680 | 6800 | exclusion | phecode |
| 619 | Noninflammatory female genital disorders | Genitourinary | 1.02 | 0.994 – 1.04 | 0.157 | 9258 | 92573 | exclusion | phecode |
| 619.1 |
Noninflammatory disorders of ovary, fallopianNoninflammatory disorders of ovary, fallopian tube, and broad ligament
|
Genitourinary | 1.01 | 0.931 – 1.09 | 0.861 | 722 | 7220 | exclusion | phecode |
| 619.2 | Disorders of uterus, NEC | Genitourinary | 1.01 | 0.974 – 1.05 | 0.56 | 3312 | 33120 | exclusion | phecode |
| 619.3 | Noninflammatory disorders of cervix | Genitourinary | 1.01 | 0.975 – 1.05 | 0.488 | 2852 | 28513 | exclusion | phecode |
| 619.4 | Noninflammatory disorders of vagina | Genitourinary | 1.02 | 0.97 – 1.07 | 0.442 | 1764 | 17640 | exclusion | phecode |
| 619.5 | Noninflammatory disorders of vulva and perineum | Genitourinary | 1.03 | 0.974 – 1.09 | 0.289 | 1342 | 13420 | exclusion | phecode |
| 620 | Dysplasia of female genital organs | Genitourinary | 0.886 | 0.684 – 1.14 | 0.348 | 72 | 720 | exclusion | phecode |
| 621 | Endometrial hyperplasia | Genitourinary | 1.02 | 0.958 – 1.09 | 0.525 | 1132 | 11320 | exclusion | phecode |
| 622 | Polyp of female genital organs | Genitourinary | 1.03 | 1.01 – 1.05 | 0.00299 | 10804 | 108040 | exclusion | phecode |
| 622.1 | Polyp of corpus uteri | Genitourinary | 1.02 | 0.997 – 1.05 | 0.0868 | 7854 | 78540 | exclusion | phecode |
| 622.2 | Mucous polyp of cervix | Genitourinary | 1.08 | 1.04 – 1.12 | 2.21e-05 | 3422 | 34220 | exclusion | phecode |
| 623 | Hypertrophy of female genital organs | Genitourinary | 1 | 0.943 – 1.06 | 0.99 | 1270 | 12700 | exclusion | phecode |
| 624 | Symptoms involving female genital tract | Genitourinary | 1 | 0.929 – 1.08 | 0.967 | 810 | 8095 | exclusion | phecode |
| 624.1 | Dystrophy of female genital tract | Genitourinary | 0.921 | 0.801 – 1.06 | 0.245 | 237 | 2370 | exclusion | phecode |
| 624.2 | Atrophy of female genital tract | Genitourinary | 1.05 | 0.947 – 1.16 | 0.364 | 441 | 4410 | exclusion | phecode |
| 625 |
Pain and other symptoms associated with femalePain and other symptoms associated with female genital organs
|
Genitourinary | 1.04 | 1 – 1.08 | 0.0468 | 2996 | 29960 | exclusion | phecode |
| 625.1 | Dyspareunia | Genitourinary | 1.04 | 0.983 – 1.11 | 0.16 | 1188 | 11880 | exclusion | phecode |
| 626 |
Disorders of menstruation and other abnormalDisorders of menstruation and other abnormal bleeding from female genital tract
|
Genitourinary | 1.01 | 0.996 – 1.03 | 0.155 | 18324 | 129160 | exclusion | phecode |
| 626.1 | Irregular menstrual cycle/bleeding | Genitourinary | 1.01 | 0.991 – 1.03 | 0.346 | 15686 | 122281 | exclusion | phecode |
| 626.11 | Absent or infrequent menstruation | Genitourinary | 1.15 | 0.968 – 1.37 | 0.106 | 144 | 1440 | exclusion | phecode |
| 626.12 | Excessive or frequent menstruation | Genitourinary | 1.02 | 0.995 – 1.04 | 0.132 | 9734 | 91841 | exclusion | phecode |
| 626.13 | Irregular menstrual cycle | Genitourinary | 1 | 0.957 – 1.05 | 0.88 | 1985 | 19849 | exclusion | phecode |
| 626.14 | Irregular menstrual bleeding | Genitourinary | 0.991 | 0.958 – 1.03 | 0.622 | 3809 | 38080 | exclusion | phecode |
| 626.2 | Dysmenorrhea | Genitourinary | 0.972 | 0.924 – 1.02 | 0.262 | 1781 | 17801 | exclusion | phecode |
| 626.4 | Premenstrual tension syndromes | Genitourinary | 0.981 | 0.829 – 1.16 | 0.818 | 159 | 1588 | exclusion | phecode |
| 626.8 | Infertility, female | Genitourinary | 1.07 | 1.01 – 1.13 | 0.0197 | 1366 | 13624 | exclusion | phecode |
| 627 | Menopausal and postmenopausal disorders | Genitourinary | 1.01 | 0.988 – 1.03 | 0.422 | 10631 | 106298 | exclusion | phecode |
| 627.1 | Postmenopausal bleeding | Genitourinary | 1.01 | 0.989 – 1.03 | 0.314 | 9055 | 90540 | exclusion | phecode |
| 627.2 | Symptomatic menopause | Genitourinary | 0.884 | 0.753 – 1.04 | 0.129 | 184 | 1839 | exclusion | phecode |
| 627.3 | Postmenopausal atrophic vaginitis | Genitourinary | 0.993 | 0.932 – 1.06 | 0.831 | 1114 | 11140 | exclusion | phecode |
| 627.4 | Premenopausal menorrhagia | Genitourinary | 0.956 | 0.848 – 1.08 | 0.46 | 311 | 3110 | exclusion | phecode |
| 628 | Ovarian cyst | Genitourinary | 1.03 | 1 – 1.06 | 0.0493 | 4755 | 47550 | exclusion | phecode |
| 634 | Miscarriage; stillbirth | Pregnancy Complications | 1.02 | 0.989 – 1.05 | 0.227 | 5450 | 38533 | exclusion | phecode |
| 634.1 | Missed abortion/Hydatidiform mole | Pregnancy Complications | 1.05 | 0.99 – 1.11 | 0.101 | 1251 | 12453 | exclusion | phecode |
| 634.3 | Ectopic pregnancy | Pregnancy Complications | 1.03 | 0.917 – 1.15 | 0.618 | 331 | 3307 | exclusion | phecode |
| 635 |
Hemorrhage during pregnancy; childbirth andHemorrhage during pregnancy; childbirth and postpartum
|
Pregnancy Complications | 1.02 | 0.969 – 1.07 | 0.504 | 2003 | 17602 | exclusion | phecode |
| 635.2 |
Antepartum hemorrhage, abruptio placentae, andAntepartum hemorrhage, abruptio placentae, and placenta previa
|
Pregnancy Complications | 1.01 | 0.944 – 1.09 | 0.708 | 866 | 8626 | exclusion | phecode |
| 635.3 | Placenta previa and abruptio placenta | Pregnancy Complications | 1.03 | 0.973 – 1.09 | 0.291 | 1273 | 12329 | exclusion | phecode |
| 636 |
Early or threatened labor; hemorrhage in earlyEarly or threatened labor; hemorrhage in early pregnancy
|
Pregnancy Complications | 0.992 | 0.951 – 1.03 | 0.703 | 2553 | 22013 | exclusion | phecode |
| 636.2 | Early onset of delivery | Pregnancy Complications | 0.986 | 0.906 – 1.07 | 0.743 | 617 | 6155 | exclusion | phecode |
| 636.3 | Hemorrhage in early pregnancy | Pregnancy Complications | 1 | 0.94 – 1.07 | 0.951 | 1082 | 10774 | exclusion | phecode |
| 638 | Other high-risk pregnancy | Pregnancy Complications | 0.935 | 0.726 – 1.2 | 0.595 | 70 | 700 | exclusion | phecode |
| 642 |
Hypertension complicating pregnancyHypertension complicating pregnancy, childbirth, and the puerperium
|
Pregnancy Complications | 0.962 | 0.904 – 1.02 | 0.231 | 1112 | 11107 | exclusion | phecode |
| 642.1 | Preeclampsia and eclampsia | Pregnancy Complications | 1.03 | 0.912 – 1.16 | 0.651 | 307 | 3063 | exclusion | phecode |
| 643 | Excessive vomiting in pregnancy | Pregnancy Complications | 1.22 | 1.07 – 1.4 | 0.00327 | 230 | 2299 | exclusion | phecode |
| 643.1 | Hyperemesis gravidarum | Pregnancy Complications | 1.14 | 0.963 – 1.35 | 0.125 | 153 | 1529 | exclusion | phecode |
| 645 | Late pregnancy and failed induction | Pregnancy Complications | 1.02 | 0.962 – 1.08 | 0.491 | 1253 | 12474 | exclusion | phecode |
| 646 | Other complications of pregnancy NEC | Pregnancy Complications | 0.972 | 0.929 – 1.02 | 0.208 | 2230 | 20875 | exclusion | phecode |
| 647 |
Infectious and parasitic complicationsInfectious and parasitic complications affecting pregnancy
|
Pregnancy Complications | 0.851 | 0.653 – 1.1 | 0.218 | 68 | 680 | exclusion | phecode |
| 649 |
Other conditions or status of the motherOther conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
|
Pregnancy Complications | 0.985 | 0.808 – 1.2 | 0.883 | 113 | 1130 | exclusion | phecode |
| 650 | Normal delivery | Pregnancy Complications | 0.989 | 0.943 – 1.04 | 0.651 | 1925 | 19003 | exclusion | phecode |
| 651 | Multiple gestation | Pregnancy Complications | 1 | 0.893 – 1.12 | 0.993 | 346 | 3460 | exclusion | phecode |
| 652 |
Malposition and malpresentation of fetus orMalposition and malpresentation of fetus or obstruction
|
Pregnancy Complications | 1.02 | 0.973 – 1.08 | 0.374 | 1718 | 16535 | exclusion | phecode |
| 653 |
Problems associated with amniotic cavity andProblems associated with amniotic cavity and membranes
|
Pregnancy Complications | 0.981 | 0.928 – 1.04 | 0.511 | 1401 | 13662 | exclusion | phecode |
| 654 |
Other and unspecified complications of birthOther and unspecified complications of birth; puerperium affecting management of mother
|
Pregnancy Complications | 1.09 | 0.852 – 1.38 | 0.487 | 74 | 740 | exclusion | phecode |
| 655 |
Known or suspected fetal abnormality affectingKnown or suspected fetal abnormality affecting management of mother
|
Pregnancy Complications | 0.968 | 0.937 – 1 | 0.054 | 4309 | 29472 | exclusion | phecode |
| 656 | Other perinatal conditions of fetus or newborn | Pregnancy Complications | 0.923 | 0.754 – 1.12 | 0.426 | 110 | 1090 | exclusion | phecode |
| 661 | Fetal distress and abnormal forces of labor | Pregnancy Complications | 0.953 | 0.911 – 0.996 | 0.034 | 2267 | 18423 | exclusion | phecode |
| 663 |
Umbilical cord complications during labor andUmbilical cord complications during labor and delivery
|
Pregnancy Complications | 1 | 0.915 – 1.1 | 0.974 | 533 | 5319 | exclusion | phecode |
| 665 | Obstetrical/birth trauma | Pregnancy Complications | 0.983 | 0.954 – 1.01 | 0.263 | 5314 | 29494 | exclusion | phecode |
| 669 | Complications of labor and delivery NEC | Pregnancy Complications | 0.987 | 0.946 – 1.03 | 0.537 | 2554 | 21200 | exclusion | phecode |
| 671 |
Venous/cerebrovascular complications embolismVenous/cerebrovascular complications embolism in pregnancy and the puerperium
|
Pregnancy Complications | 0.968 | 0.821 – 1.14 | 0.694 | 164 | 1630 | exclusion | phecode |
| 674 | Other complications of the puerperium NEC | Pregnancy Complications | 0.871 | 0.763 – 0.992 | 0.0374 | 262 | 2609 | exclusion | phecode |
| 676 |
Other disorders of the breast associated withOther disorders of the breast associated with childbirth and disorders of lactation
|
Pregnancy Complications | 0.97 | 0.744 – 1.25 | 0.814 | 63 | 624 | exclusion | phecode |
| 679 | Complications of in utero procedures | Dermatologic | 1.35 | 1.01 – 1.81 | 0.0383 | 53 | 530 | exclusion | phecode |
| 681 | Superficial cellulitis and abscess | Dermatologic | 1.02 | 0.999 – 1.05 | 0.0597 | 7421 | 74210 | exclusion | phecode |
| 681.1 | Cellulitis and abscess of fingers/toes | Dermatologic | 1.05 | 0.965 – 1.15 | 0.235 | 566 | 5660 | exclusion | phecode |
| 681.2 | Cellulitis and abscess of face/neck | Dermatologic | 1.05 | 0.957 – 1.15 | 0.297 | 522 | 5220 | exclusion | phecode |
| 681.3 | Cellulitis and abscess of arm/hand | Dermatologic | 1.02 | 0.992 – 1.05 | 0.155 | 5514 | 55140 | exclusion | phecode |
| 681.5 | Cellulitis and abscess of leg, except foot | Dermatologic | 1.02 | 0.993 – 1.05 | 0.133 | 5521 | 55210 | exclusion | phecode |
| 681.6 | Cellulitis and abscess of foot, toe | Dermatologic | 1.02 | 0.994 – 1.05 | 0.123 | 5477 | 54770 | exclusion | phecode |
| 681.7 | Cellulitis and abscess of trunk | Dermatologic | 1.05 | 0.959 – 1.14 | 0.301 | 600 | 6000 | exclusion | phecode |
| 686 |
Other local infections of skin and subcutaneousOther local infections of skin and subcutaneous tissue
|
Dermatologic | 1.06 | 1 – 1.13 | 0.0387 | 1348 | 13480 | exclusion | phecode |
| 686.1 | Carbuncle and furuncle | Dermatologic | 1.25 | 1 – 1.56 | 0.0455 | 87 | 870 | exclusion | phecode |
| 687 | Symptoms affecting skin | Dermatologic | 1.02 | 0.934 – 1.11 | 0.662 | 604 | 6040 | exclusion | phecode |
| 687.2 | Localized superficial swelling, mass, or lump | Dermatologic | 0.948 | 0.834 – 1.08 | 0.406 | 284 | 2840 | exclusion | phecode |
| 687.3 | Changes in skin texture | Dermatologic | 1 | 0.807 – 1.23 | 0.997 | 108 | 1080 | exclusion | phecode |
| 689 | Disorder of skin and subcutaneous tissue NOS | Dermatologic | 1.02 | 0.989 – 1.05 | 0.217 | 5765 | 57650 | exclusion | phecode |
| 690 | Erythematosquamous dermatosis | Dermatologic | 1.11 | 0.855 – 1.43 | 0.42 | 72 | 720 | exclusion | phecode |
| 690.1 | Seborrheic dermatitis | Dermatologic | 1.08 | 0.789 – 1.47 | 0.614 | 53 | 530 | exclusion | phecode |
| 691 | Congenital anomalies of skin | Dermatologic | 1.14 | 0.933 – 1.39 | 0.191 | 120 | 1200 | exclusion | phecode |
| 694 | Dyschromia and Vitiligo | Dermatologic | 1.03 | 0.953 – 1.11 | 0.491 | 987 | 9864 | exclusion | phecode |
| 694.1 | Vitiligo | Dermatologic | 0.917 | 0.695 – 1.2 | 0.526 | 60 | 600 | exclusion | phecode |
| 694.2 | Other dyschromia | Dermatologic | 1.02 | 0.938 – 1.11 | 0.616 | 783 | 7830 | exclusion | phecode |
| 694.3 | Vascular disorders of skin | Dermatologic | 1.17 | 0.963 – 1.42 | 0.109 | 117 | 1164 | exclusion | phecode |
| 695 | Erythematous conditions | Dermatologic | 1.02 | 0.977 – 1.07 | 0.367 | 2416 | 24160 | exclusion | phecode |
| 695.1 | Toxic erythema | Dermatologic | 1 | 0.815 – 1.23 | 0.991 | 109 | 1090 | exclusion | phecode |
| 695.2 | Bullous dermatoses | Dermatologic | 0.986 | 0.821 – 1.18 | 0.875 | 141 | 1410 | exclusion | phecode |
| 695.21 | Dermatitis herpetiformis | Dermatologic | 0.905 | 0.672 – 1.21 | 0.494 | 57 | 570 | exclusion | phecode |
| 695.22 | Pemphigus and pemphigoid | Dermatologic | 1.07 | 0.831 – 1.36 | 0.606 | 75 | 750 | exclusion | phecode |
| 695.3 | Rosacea | Dermatologic | 1.05 | 0.926 – 1.19 | 0.454 | 310 | 3100 | exclusion | phecode |
| 695.4 | Lupus (localized and systemic) | Dermatologic | 1.02 | 0.92 – 1.13 | 0.695 | 418 | 4180 | exclusion | phecode |
| 695.41 | Cutaneous lupus erythematosus | Dermatologic | 1.18 | 0.982 – 1.41 | 0.073 | 130 | 1300 | exclusion | phecode |
| 695.42 | Systemic lupus erythematosus | Dermatologic | 0.949 | 0.845 – 1.07 | 0.377 | 342 | 3420 | exclusion | phecode |
| 695.7 | Prurigo and Lichen | Dermatologic | 1.01 | 0.936 – 1.09 | 0.776 | 777 | 7770 | exclusion | phecode |
| 695.8 | Other specified erythematous conditions | Dermatologic | 1.07 | 0.93 – 1.22 | 0.348 | 242 | 2420 | exclusion | phecode |
| 695.81 | Erythema nodosum | Dermatologic | 1.04 | 0.812 – 1.31 | 0.771 | 76 | 760 | exclusion | phecode |
| 695.9 | Unspecified erythematous condition | Dermatologic | 1.03 | 0.932 – 1.14 | 0.565 | 468 | 4680 | exclusion | phecode |
| 696 | Psoriasis and related disorders | Dermatologic | 0.988 | 0.945 – 1.03 | 0.596 | 2290 | 22900 | exclusion | phecode |
| 696.4 | Psoriasis | Dermatologic | 0.989 | 0.945 – 1.03 | 0.618 | 2234 | 22340 | exclusion | phecode |
| 696.41 | Psoriasis vulgaris | Dermatologic | 1.01 | 0.956 – 1.06 | 0.772 | 1681 | 16810 | exclusion | phecode |
| 696.42 | Psoriatic arthropathy | Dermatologic | 0.944 | 0.87 – 1.02 | 0.156 | 708 | 7080 | exclusion | phecode |
| 697 | Sarcoidosis | Dermatologic | 0.948 | 0.865 – 1.04 | 0.256 | 549 | 5480 | exclusion | phecode |
| 698 | Pruritus and related conditions | Dermatologic | 1.01 | 0.937 – 1.09 | 0.784 | 783 | 7830 | exclusion | phecode |
| 700 | Corns and callosities | Dermatologic | 1.03 | 0.908 – 1.17 | 0.642 | 293 | 2930 | exclusion | phecode |
| 701 |
Other hypertrophic and atrophic conditions ofOther hypertrophic and atrophic conditions of skin
|
Dermatologic | 1.04 | 1.01 – 1.07 | 0.0202 | 4782 | 47820 | exclusion | phecode |
| 701.1 | Keratoderma, acquired | Dermatologic | 0.964 | 0.755 – 1.23 | 0.763 | 86 | 860 | exclusion | phecode |
| 701.2 | Scar conditions and fibrosis of skin | Dermatologic | 1.06 | 1.01 – 1.11 | 0.0163 | 2350 | 23500 | exclusion | phecode |
| 701.3 | Circumscribed scleroderma | Dermatologic | 0.902 | 0.679 – 1.19 | 0.463 | 59 | 590 | exclusion | phecode |
| 701.4 | Keloid scar | Dermatologic | 1.03 | 0.88 – 1.19 | 0.739 | 216 | 2160 | exclusion | phecode |
| 701.5 | Abnormal granulation tissue | Dermatologic | 0.988 | 0.891 – 1.1 | 0.825 | 454 | 4540 | exclusion | phecode |
| 701.6 | Acquired acanthosis nigricans | Dermatologic | 1.1 | 0.879 – 1.38 | 0.381 | 102 | 1020 | exclusion | phecode |
| 702 |
Degenerative skin conditions and otherDegenerative skin conditions and other dermatoses
|
Dermatologic | 1.08 | 1.05 – 1.12 | 1.9e-06 | 5492 | 54920 | exclusion | phecode |
| 702.1 | Actinic keratosis | Dermatologic | 1.19 | 1.13 – 1.24 | 4.98e-12 | 2581 | 25810 | exclusion | phecode |
| 702.2 | Seborrheic keratosis | Dermatologic | 1.01 | 0.973 – 1.06 | 0.492 | 3075 | 30750 | exclusion | phecode |
| 703 | Diseases of nail, NOS | Dermatologic | 1.01 | 0.9 – 1.13 | 0.864 | 355 | 3546 | exclusion | phecode |
| 704 | Diseases of hair and hair follicles | Dermatologic | 1.05 | 1.02 – 1.08 | 0.000492 | 5287 | 52864 | exclusion | phecode |
| 704.1 | Alopecia | Dermatologic | 0.899 | 0.736 – 1.09 | 0.281 | 127 | 1270 | exclusion | phecode |
| 704.8 |
Other specified diseases of hair and hairOther specified diseases of hair and hair follicles
|
Dermatologic | 1.02 | 0.78 – 1.32 | 0.908 | 76 | 760 | exclusion | phecode |
| 705 | Disorders of sweat glands | Dermatologic | 0.984 | 0.855 – 1.13 | 0.818 | 229 | 2289 | exclusion | phecode |
| 705.3 | Hidradenitis | Dermatologic | 0.985 | 0.843 – 1.15 | 0.851 | 187 | 1869 | exclusion | phecode |
| 706 | Diseases of sebaceous glands | Dermatologic | 1.06 | 1.04 – 1.08 | 3.06e-07 | 8876 | 88734 | exclusion | phecode |
| 706.1 | Acne | Dermatologic | 0.879 | 0.686 – 1.12 | 0.296 | 78 | 780 | exclusion | phecode |
| 706.2 | Sebaceous cyst | Dermatologic | 1.06 | 1.04 – 1.09 | 1.96e-07 | 8804 | 88014 | exclusion | phecode |
| 707 | Chronic ulcer of skin | Dermatologic | 1.02 | 0.968 – 1.06 | 0.533 | 1990 | 19900 | exclusion | phecode |
| 707.1 | Decubitus ulcer | Dermatologic | 1.03 | 0.962 – 1.11 | 0.38 | 913 | 9130 | exclusion | phecode |
| 709 | Diffuse diseases of connective tissue | Dermatologic | 0.968 | 0.934 – 1 | 0.081 | 3451 | 34510 | exclusion | phecode |
| 709.2 | Sicca syndrome | Dermatologic | 0.952 | 0.865 – 1.05 | 0.306 | 504 | 5040 | exclusion | phecode |
| 709.3 | Systemic sclerosis | Dermatologic | 1 | 0.854 – 1.18 | 0.954 | 174 | 1740 | exclusion | phecode |
| 709.6 |
Other specified diffuse diseases of connectiveOther specified diffuse diseases of connective tissue
|
Dermatologic | 0.935 | 0.714 – 1.22 | 0.618 | 65 | 650 | exclusion | phecode |
| 709.7 | Unspecified diffuse connective tissue disease | Dermatologic | 0.97 | 0.931 – 1.01 | 0.137 | 2721 | 27210 | exclusion | phecode |
| 710 |
Osteomyelitis, periostitis, and otherOsteomyelitis, periostitis, and other infections involving bone
|
Musculoskeletal | 1.02 | 0.939 – 1.11 | 0.602 | 613 | 6130 | exclusion | phecode |
| 710.1 | Osteomyelitis | Musculoskeletal | 1.03 | 0.94 – 1.12 | 0.546 | 566 | 5660 | exclusion | phecode |
| 710.12 | Chronic osteomyelitis | Musculoskeletal | 1.06 | 0.911 – 1.23 | 0.439 | 196 | 1960 | exclusion | phecode |
| 710.19 | Unspecified osteomyelitis | Musculoskeletal | 1 | 0.9 – 1.11 | 0.98 | 402 | 4020 | exclusion | phecode |
| 711 | Arthropathy associated with infections | Musculoskeletal | 1.03 | 0.933 – 1.14 | 0.531 | 429 | 4290 | exclusion | phecode |
| 711.1 | Pyogenic arthritis | Musculoskeletal | 1.07 | 0.951 – 1.2 | 0.261 | 330 | 3300 | exclusion | phecode |
| 712 | Infective connective tissue disorders | Musculoskeletal | 1.13 | 0.894 – 1.42 | 0.301 | 82 | 820 | exclusion | phecode |
| 713 |
Arthropathy associated with other disordersArthropathy associated with other disorders classified elsewhere
|
Musculoskeletal | 0.994 | 0.835 – 1.18 | 0.945 | 151 | 1510 | exclusion | phecode |
| 713.5 |
Arthropathy associated with neurologicalArthropathy associated with neurological disorders
|
Musculoskeletal | 0.943 | 0.725 – 1.22 | 0.652 | 68 | 680 | exclusion | phecode |
| 714 |
Rheumatoid arthritis and other inflammatoryRheumatoid arthritis and other inflammatory polyarthropathies
|
Musculoskeletal | 1.03 | 0.996 – 1.06 | 0.0941 | 4858 | 48575 | exclusion | phecode |
| 714.1 | Rheumatoid arthritis | Musculoskeletal | 1.03 | 0.999 – 1.06 | 0.0603 | 4394 | 43935 | exclusion | phecode |
| 715 | Other inflammatory spondylopathies | Musculoskeletal | 1.04 | 0.991 – 1.1 | 0.104 | 1670 | 16700 | exclusion | phecode |
| 715.1 | Sacroiliitis NEC | Musculoskeletal | 1.42 | 1.17 – 1.73 | 0.000335 | 113 | 1130 | exclusion | phecode |
| 715.2 | Ankylosing spondylitis | Musculoskeletal | 0.994 | 0.913 – 1.08 | 0.887 | 619 | 6190 | exclusion | phecode |
| 716 | Other arthropathies | Musculoskeletal | 1.01 | 0.995 – 1.02 | 0.317 | 37608 | 265965 | exclusion | phecode |
| 716.1 | Unspecified polyarthropathy or polyarthritis | Musculoskeletal | 1.06 | 1.02 – 1.1 | 0.00116 | 3517 | 35170 | exclusion | phecode |
| 716.2 | Unspecified monoarthritis | Musculoskeletal | 1.01 | 0.992 – 1.03 | 0.288 | 15561 | 155610 | exclusion | phecode |
| 716.9 | Arthropathy NOS | Musculoskeletal | 1 | 0.993 – 1.02 | 0.421 | 35982 | 254727 | exclusion | phecode |
| 717 | Polymyalgia Rheumatica | Musculoskeletal | 1.02 | 0.958 – 1.08 | 0.545 | 1152 | 11520 | exclusion | phecode |
| 720 | Spinal stenosis | Musculoskeletal | 1 | 0.966 – 1.04 | 0.98 | 3715 | 37150 | exclusion | phecode |
| 721 | Spondylosis and allied disorders | Musculoskeletal | 1.03 | 1.01 – 1.06 | 0.012 | 7872 | 78720 | exclusion | phecode |
| 721.1 | Spondylosis without myelopathy | Musculoskeletal | 1.02 | 0.993 – 1.05 | 0.131 | 5042 | 50420 | exclusion | phecode |
| 721.2 | Spondylosis with myelopathy | Musculoskeletal | 1.08 | 0.932 – 1.26 | 0.287 | 189 | 1890 | exclusion | phecode |
| 721.8 | Other allied disorders of spine | Musculoskeletal | 1.1 | 0.981 – 1.22 | 0.104 | 351 | 3510 | exclusion | phecode |
| 722 | Intervertebral disc disorders | Musculoskeletal | 1 | 0.982 – 1.03 | 0.695 | 9170 | 91700 | exclusion | phecode |
| 722.1 | Displacement of intervertebral disc | Musculoskeletal | 1.1 | 0.998 – 1.2 | 0.0541 | 508 | 5080 | exclusion | phecode |
| 722.6 | Degeneration of intervertebral disc | Musculoskeletal | 1.02 | 0.979 – 1.06 | 0.358 | 2826 | 28260 | exclusion | phecode |
| 722.8 | Postlaminectomy syndrome | Musculoskeletal | 1.06 | 0.821 – 1.37 | 0.638 | 67 | 670 | exclusion | phecode |
| 722.9 | Other and unspecified disc disorder | Musculoskeletal | 0.986 | 0.955 – 1.02 | 0.378 | 4398 | 43980 | exclusion | phecode |
| 723 | Other disorders of cervical region | Musculoskeletal | 0.956 | 0.872 – 1.05 | 0.342 | 521 | 5210 | exclusion | phecode |
| 723.1 | Torticollis | Musculoskeletal | 0.976 | 0.796 – 1.19 | 0.81 | 107 | 1070 | exclusion | phecode |
| 724 | Other and unspecified disorders of back | Musculoskeletal | 1 | 0.959 – 1.05 | 0.838 | 2076 | 20760 | exclusion | phecode |
| 724.1 | Disorders of sacrum | Musculoskeletal | 0.934 | 0.839 – 1.04 | 0.212 | 404 | 4040 | exclusion | phecode |
| 724.2 | Disorders of coccyx | Musculoskeletal | 0.923 | 0.829 – 1.03 | 0.14 | 407 | 4070 | exclusion | phecode |
| 724.8 | Other symptoms referable to back | Musculoskeletal | 1.04 | 0.804 – 1.35 | 0.737 | 63 | 630 | exclusion | phecode |
| 724.9 | Other unspecified back disorders | Musculoskeletal | 1.02 | 0.969 – 1.08 | 0.435 | 1616 | 16160 | exclusion | phecode |
| 726 | Peripheral enthesopathies and allied syndromes | Musculoskeletal | 0.996 | 0.979 – 1.01 | 0.652 | 14821 | 148210 | exclusion | phecode |
| 726.1 | Enthesopathy | Musculoskeletal | 1 | 0.981 – 1.02 | 0.836 | 9557 | 95570 | exclusion | phecode |
| 726.2 | Synoviopathy | Musculoskeletal | 0.928 | 0.824 – 1.04 | 0.216 | 330 | 3300 | exclusion | phecode |
| 726.3 | Bursitis | Musculoskeletal | 0.934 | 0.868 – 1 | 0.0653 | 856 | 8560 | exclusion | phecode |
| 727 | Other disorders of synovium, tendon, and bursa | Musculoskeletal | 1 | 0.978 – 1.03 | 0.859 | 7593 | 75930 | exclusion | phecode |
| 727.1 | Synovitis and tenosynovitis | Musculoskeletal | 1.01 | 0.97 – 1.05 | 0.615 | 2738 | 27380 | exclusion | phecode |
| 727.2 | Bursitis disorders | Musculoskeletal | 1.11 | 0.906 – 1.35 | 0.304 | 106 | 1060 | exclusion | phecode |
| 727.4 | Ganglion and cyst of synovium, tendon, and bursa | Musculoskeletal | 0.977 | 0.941 – 1.01 | 0.235 | 3175 | 31750 | exclusion | phecode |
| 727.5 | Rupture of synovium | Musculoskeletal | 1.03 | 0.941 – 1.12 | 0.55 | 587 | 5870 | exclusion | phecode |
| 727.6 | Rupture of tendon, nontraumatic | Musculoskeletal | 0.982 | 0.876 – 1.1 | 0.76 | 352 | 3520 | exclusion | phecode |
| 727.7 | Contracture of tendon (sheath) | Musculoskeletal | 1 | 0.838 – 1.2 | 0.972 | 142 | 1420 | exclusion | phecode |
| 728 | Disorders of muscle, ligament, and fascia | Musculoskeletal | 1.01 | 0.976 – 1.05 | 0.54 | 3697 | 36970 | exclusion | phecode |
| 728.7 | Fasciitis | Musculoskeletal | 1.02 | 0.982 – 1.06 | 0.332 | 3482 | 34820 | exclusion | phecode |
| 728.71 |
Contracture of palmar fascia [Dupuytren'sContracture of palmar fascia [Dupuytren's disease]
|
Musculoskeletal | 1.02 | 0.982 – 1.06 | 0.331 | 3482 | 34820 | exclusion | phecode |
| 729 | Other disorders of soft tissues | Musculoskeletal | 0.977 | 0.951 – 1 | 0.0923 | 6051 | 60510 | exclusion | phecode |
| 729.1 | Rheumatism, unspecified and fibrositis | Musculoskeletal | 1.02 | 0.951 – 1.09 | 0.62 | 1004 | 10040 | exclusion | phecode |
| 731 |
Osteitis deformans and osteopathies associatedOsteitis deformans and osteopathies associated with other disorders classified elsewhere
|
Musculoskeletal | 0.897 | 0.787 – 1.02 | 0.102 | 277 | 2770 | exclusion | phecode |
| 731.1 | Osteitis deformans [Paget's disease of bone] | Musculoskeletal | 0.906 | 0.791 – 1.03 | 0.145 | 262 | 2620 | exclusion | phecode |
| 732 | Osteochondropathies | Musculoskeletal | 0.911 | 0.826 – 1 | 0.0618 | 472 | 4720 | exclusion | phecode |
| 732.1 | Juvenile osteochondrosis | Musculoskeletal | 0.876 | 0.753 – 1.02 | 0.0824 | 207 | 2070 | exclusion | phecode |
| 732.7 | Osteochondritis dissecans | Musculoskeletal | 1 | 0.762 – 1.31 | 0.999 | 59 | 590 | exclusion | phecode |
| 733 | Other disorders of bone and cartilage | Musculoskeletal | 1.02 | 0.97 – 1.07 | 0.446 | 1792 | 17920 | exclusion | phecode |
| 733.2 | Cyst of bone | Musculoskeletal | 1.07 | 0.949 – 1.2 | 0.271 | 319 | 3190 | exclusion | phecode |
| 735 | Acquired foot deformities | Musculoskeletal | 1.01 | 0.989 – 1.03 | 0.357 | 9764 | 97640 | exclusion | phecode |
| 735.1 | Flat foot | Musculoskeletal | 1.13 | 0.97 – 1.31 | 0.113 | 190 | 1900 | exclusion | phecode |
| 735.2 | Acquired toe deformities | Musculoskeletal | 1.02 | 0.99 – 1.05 | 0.192 | 5091 | 50910 | exclusion | phecode |
| 735.21 | Hammer toe (acquired) | Musculoskeletal | 1.01 | 0.964 – 1.06 | 0.632 | 1914 | 19140 | exclusion | phecode |
| 735.23 | Hallux rigidus | Musculoskeletal | 1.03 | 0.971 – 1.08 | 0.363 | 1548 | 15480 | exclusion | phecode |
| 735.3 | Hallux valgus (Bunion) | Musculoskeletal | 1 | 0.977 – 1.03 | 0.846 | 6639 | 66390 | exclusion | phecode |
| 736 | Other acquired deformities of limbs | Musculoskeletal | 0.97 | 0.921 – 1.02 | 0.262 | 1644 | 16440 | exclusion | phecode |
| 736.2 | Acquired deformities of finger | Musculoskeletal | 1.04 | 0.907 – 1.19 | 0.577 | 248 | 2480 | exclusion | phecode |
| 737 | Curvature of spine | Musculoskeletal | 1.04 | 0.981 – 1.11 | 0.176 | 1135 | 11350 | exclusion | phecode |
| 737.3 | Kyphoscoliosis and scoliosis | Musculoskeletal | 1.03 | 0.968 – 1.1 | 0.324 | 1064 | 10640 | exclusion | phecode |
| 738 | Other acquired musculoskeletal deformity | Musculoskeletal | 1.02 | 0.974 – 1.07 | 0.383 | 1921 | 19210 | exclusion | phecode |
| 738.4 | Acquired spondylolisthesis | Musculoskeletal | 1.02 | 0.963 – 1.07 | 0.548 | 1520 | 15200 | exclusion | phecode |
| 739 | Contracture of joint | Musculoskeletal | 1.12 | 1.01 – 1.23 | 0.0227 | 489 | 4890 | exclusion | phecode |
| 740 | Osteoarthrosis | Musculoskeletal | 1.01 | 0.994 – 1.02 | 0.29 | 27860 | 232406 | exclusion | phecode |
| 740.1 | Osteoarthritis; localized | Musculoskeletal | 1.01 | 0.993 – 1.03 | 0.291 | 17461 | 169819 | exclusion | phecode |
| 740.11 | Osteoarthrosis, localized, primary | Musculoskeletal | 1.02 | 0.998 – 1.04 | 0.0714 | 8997 | 89952 | exclusion | phecode |
| 740.12 | Osteoarthrosis, localized, secondary | Musculoskeletal | 1.07 | 0.956 – 1.2 | 0.235 | 348 | 3480 | exclusion | phecode |
| 740.2 | Osteoarthrosis, generalized | Musculoskeletal | 1.14 | 1.05 – 1.25 | 0.00227 | 599 | 5990 | exclusion | phecode |
| 740.9 | Osteoarthrosis NOS | Musculoskeletal | 1.01 | 0.993 – 1.03 | 0.2 | 12302 | 123014 | exclusion | phecode |
| 741 | Symptoms and disorders of the joints | Musculoskeletal | 1.01 | 0.978 – 1.05 | 0.461 | 3624 | 36240 | exclusion | phecode |
| 741.1 | Ankylosis of joint | Musculoskeletal | 1.03 | 0.833 – 1.26 | 0.799 | 102 | 1020 | exclusion | phecode |
| 741.2 | Stiffness of joint | Musculoskeletal | 0.991 | 0.909 – 1.08 | 0.843 | 614 | 6140 | exclusion | phecode |
| 741.3 | Difficulty in walking | Musculoskeletal | 0.963 | 0.81 – 1.14 | 0.663 | 155 | 1550 | exclusion | phecode |
| 741.4 | Joint effusions | Musculoskeletal | 1.05 | 0.991 – 1.11 | 0.1 | 1420 | 14200 | exclusion | phecode |
| 741.5 | Hemarthrosis | Musculoskeletal | 0.929 | 0.759 – 1.13 | 0.47 | 111 | 1110 | exclusion | phecode |
| 741.6 | Villonodular synovitis | Musculoskeletal | 0.802 | 0.593 – 1.07 | 0.138 | 54 | 540 | exclusion | phecode |
| 742 | Derangement of joint, non-traumatic | Musculoskeletal | 1.01 | 0.969 – 1.05 | 0.682 | 2906 | 29060 | exclusion | phecode |
| 742.1 | Loose body in joint | Musculoskeletal | 0.947 | 0.842 – 1.06 | 0.361 | 332 | 3320 | exclusion | phecode |
| 742.2 |
Pathological, developmental or recurrentPathological, developmental or recurrent dislocation
|
Musculoskeletal | 0.894 | 0.723 – 1.1 | 0.294 | 96 | 960 | exclusion | phecode |
| 742.8 | Articular cartilage disorder | Musculoskeletal | 1.01 | 0.923 – 1.11 | 0.762 | 499 | 4990 | exclusion | phecode |
| 742.9 | Other derangement of joint | Musculoskeletal | 1.01 | 0.966 – 1.06 | 0.602 | 1995 | 19950 | exclusion | phecode |
| 743 |
Osteoporosis, osteopenia and pathologicalOsteoporosis, osteopenia and pathological fracture
|
Musculoskeletal | 1.01 | 0.983 – 1.03 | 0.572 | 7628 | 76256 | exclusion | phecode |
| 743.1 | Osteoporosis | Musculoskeletal | 1 | 0.976 – 1.03 | 0.827 | 6434 | 64335 | exclusion | phecode |
| 743.11 | Osteoporosis NOS | Musculoskeletal | 0.996 | 0.968 – 1.02 | 0.776 | 5577 | 55767 | exclusion | phecode |
| 743.13 | Other specified osteoporosis | Musculoskeletal | 1.04 | 0.947 – 1.14 | 0.416 | 530 | 5299 | exclusion | phecode |
| 743.2 | Pathologic fracture | Musculoskeletal | 1.05 | 0.957 – 1.15 | 0.3 | 523 | 5230 | exclusion | phecode |
| 743.9 |
Osteopenia or other disorder of bone andOsteopenia or other disorder of bone and cartilage
|
Musculoskeletal | 1 | 0.929 – 1.08 | 0.983 | 819 | 8190 | exclusion | phecode |
| 745 | Pain in joint | Musculoskeletal | 1.03 | 1 – 1.05 | 0.0344 | 7994 | 79930 | exclusion | phecode |
| 747 | Cardiac and circulatory congenital anomalies | Congenital Anomalies | 0.981 | 0.942 – 1.02 | 0.342 | 2822 | 28217 | exclusion | phecode |
| 747.1 | Cardiac congenital anomalies | Congenital Anomalies | 0.978 | 0.938 – 1.02 | 0.295 | 2645 | 26447 | exclusion | phecode |
| 747.11 | Cardiac shunt/ heart septal defect | Congenital Anomalies | 0.999 | 0.915 – 1.09 | 0.98 | 587 | 5870 | exclusion | phecode |
| 747.12 | Valvular heart disease/ heart chambers | Congenital Anomalies | 1.04 | 0.909 – 1.2 | 0.543 | 236 | 2360 | exclusion | phecode |
| 747.13 | Congenital anomalies of great vessels | Congenital Anomalies | 0.962 | 0.915 – 1.01 | 0.131 | 1823 | 18227 | exclusion | phecode |
| 747.2 |
Congenital anomalies of peripheral vascularCongenital anomalies of peripheral vascular system
|
Congenital Anomalies | 1.01 | 0.855 – 1.18 | 0.937 | 167 | 1670 | exclusion | phecode |
| 748 | Anomalies of respiratory system, congenital | Congenital Anomalies | 0.969 | 0.721 – 1.29 | 0.828 | 51 | 510 | exclusion | phecode |
| 749 | Congenital anomalies of face and neck | Congenital Anomalies | 1.04 | 0.924 – 1.17 | 0.499 | 324 | 3240 | exclusion | phecode |
| 750 | Digestive congenital anomalies | Congenital Anomalies | 1.05 | 0.97 – 1.14 | 0.224 | 704 | 7040 | exclusion | phecode |
| 750.1 | Upper gastrointestinal congenital anomalies | Congenital Anomalies | 0.993 | 0.882 – 1.12 | 0.911 | 336 | 3360 | exclusion | phecode |
| 750.13 | Congenital anomalies of mouth/tongue | Congenital Anomalies | 0.938 | 0.801 – 1.1 | 0.418 | 193 | 1930 | exclusion | phecode |
| 750.2 | Lower gastrointestinal congenital anomalies | Congenital Anomalies | 1.11 | 0.992 – 1.24 | 0.0679 | 364 | 3640 | exclusion | phecode |
| 750.21 | Congenital anomalies of intestine | Congenital Anomalies | 1.1 | 0.963 – 1.26 | 0.153 | 229 | 2290 | exclusion | phecode |
| 750.22 |
Congenital anomaly of gallbladder, bile ductsCongenital anomaly of gallbladder, bile ducts, liver, pancreas
|
Congenital Anomalies | 1.13 | 0.925 – 1.38 | 0.224 | 118 | 1180 | exclusion | phecode |
| 751 | Genitourinary congenital anomalies | Congenital Anomalies | 0.995 | 0.943 – 1.05 | 0.84 | 1590 | 15900 | exclusion | phecode |
| 751.1 | Congenital anomalies of genital organs | Congenital Anomalies | 0.975 | 0.902 – 1.05 | 0.527 | 731 | 7310 | exclusion | phecode |
| 751.11 | Congenital anomalies of female genital organs | Congenital Anomalies | 1.01 | 0.914 – 1.11 | 0.859 | 457 | 4570 | exclusion | phecode |
| 751.12 | Congenital anomalies of male genital organs | Congenital Anomalies | 0.96 | 0.834 – 1.1 | 0.568 | 228 | 2280 | exclusion | phecode |
| 751.2 | Congenital anomalies of urinary system | Congenital Anomalies | 1 | 0.931 – 1.08 | 0.958 | 850 | 8500 | exclusion | phecode |
| 751.21 | Cystic kidney disease | Congenital Anomalies | 0.999 | 0.898 – 1.11 | 0.979 | 426 | 4260 | exclusion | phecode |
| 751.22 | Other specified congenital anomalies of kidney | Congenital Anomalies | 0.982 | 0.875 – 1.1 | 0.752 | 339 | 3390 | exclusion | phecode |
| 752 | Nervous system congenital anomalies | Congenital Anomalies | 1.02 | 0.913 – 1.15 | 0.681 | 336 | 3360 | exclusion | phecode |
| 752.1 | Neural tube defects | Congenital Anomalies | 1.02 | 0.898 – 1.16 | 0.727 | 257 | 2570 | exclusion | phecode |
| 752.11 | Spina bifida | Congenital Anomalies | 1.09 | 0.949 – 1.26 | 0.21 | 211 | 2110 | exclusion | phecode |
| 752.2 |
Other specified congenital anomalies of nervousOther specified congenital anomalies of nervous system
|
Congenital Anomalies | 1.07 | 0.846 – 1.34 | 0.569 | 80 | 800 | exclusion | phecode |
| 753 | Congenital anomalies of the eye | Congenital Anomalies | 0.854 | 0.707 – 1.03 | 0.0947 | 131 | 1310 | exclusion | phecode |
| 753.1 | Congenital cataract and lens anomalies | Congenital Anomalies | 1 | 0.787 – 1.27 | 0.976 | 76 | 760 | exclusion | phecode |
| 754 | Congenital musculoskeletal deformities of spine | Congenital Anomalies | 1.07 | 0.874 – 1.31 | 0.507 | 110 | 1100 | exclusion | phecode |
| 755 | Congenital anomalies of limbs | Congenital Anomalies | 0.979 | 0.884 – 1.08 | 0.678 | 449 | 4490 | exclusion | phecode |
| 755.1 | Congenital deformities of feet | Congenital Anomalies | 1.01 | 0.871 – 1.17 | 0.891 | 210 | 2100 | exclusion | phecode |
| 755.6 |
Other congenital anomalies of lower limbOther congenital anomalies of lower limb, including pelvic girdle
|
Congenital Anomalies | 0.964 | 0.816 – 1.14 | 0.663 | 162 | 1620 | exclusion | phecode |
| 755.61 | Congenital hip dysplasia and deformity | Congenital Anomalies | 0.884 | 0.719 – 1.08 | 0.233 | 107 | 1070 | exclusion | phecode |
| 756 | Other congenital musculoskeletal anomalies | Congenital Anomalies | 1.03 | 0.943 – 1.12 | 0.524 | 593 | 5930 | exclusion | phecode |
| 756.3 |
Congenital anomalies of muscle, tendon, fasciaCongenital anomalies of muscle, tendon, fascia, and connective tissue
|
Congenital Anomalies | 1.05 | 0.829 – 1.33 | 0.668 | 81 | 810 | exclusion | phecode |
| 756.5 | Congenital osteodystrophies | Congenital Anomalies | 1.01 | 0.911 – 1.12 | 0.864 | 436 | 4360 | exclusion | phecode |
| 758 | Chromosomal anomalies and genetic disorders | Congenital Anomalies | 1.1 | 0.944 – 1.28 | 0.216 | 189 | 1890 | exclusion | phecode |
| 758.1 | Chromosomal anomalies | Congenital Anomalies | 1.14 | 0.919 – 1.4 | 0.229 | 100 | 1000 | exclusion | phecode |
| 759 | Other and unspecified congenital anomalies | Congenital Anomalies | 1.02 | 0.891 – 1.18 | 0.736 | 233 | 2330 | exclusion | phecode |
| 759.1 | Anomalies of endocrine glands, congenital | Congenital Anomalies | 0.895 | 0.726 – 1.1 | 0.288 | 105 | 1050 | exclusion | phecode |
| 760 | Back pain | Symptoms | 1.02 | 0.996 – 1.04 | 0.125 | 11163 | 111617 | exclusion | phecode |
| 761 | Cervicalgia | Symptoms | 1.02 | 0.97 – 1.07 | 0.44 | 1792 | 17920 | exclusion | phecode |
| 764 | Sciatica | Symptoms | 0.968 | 0.927 – 1.01 | 0.145 | 2378 | 23780 | exclusion | phecode |
| 766 | Neuralgia, neuritis, and radiculitis NOS | Symptoms | 0.951 | 0.894 – 1.01 | 0.111 | 1182 | 11820 | exclusion | phecode |
| 770 | Myalgia and myositis unspecified | Symptoms | 1.03 | 0.947 – 1.12 | 0.492 | 642 | 6420 | exclusion | phecode |
| 771 | Musculoskeletal symptoms referable to limbs | Symptoms | 0.975 | 0.907 – 1.05 | 0.487 | 874 | 8732 | exclusion | phecode |
| 772 | Symptoms of the muscles | Symptoms | 1.04 | 0.962 – 1.13 | 0.295 | 676 | 6760 | exclusion | phecode |
| 773 | Pain in limb | Symptoms | 1.02 | 0.997 – 1.05 | 0.0776 | 6290 | 62896 | exclusion | phecode |
| 780 | Hypothermia/Chills | Symptoms | 1.03 | 0.876 – 1.21 | 0.71 | 172 | 1720 | exclusion | phecode |
| 781 |
Symptoms involving nervous and musculoskeletalSymptoms involving nervous and musculoskeletal systems
|
Symptoms | 0.969 | 0.923 – 1.02 | 0.212 | 1880 | 18800 | exclusion | phecode |
| 783 | Fever of unknown origin | Symptoms | 0.998 | 0.965 – 1.03 | 0.93 | 3930 | 39300 | exclusion | phecode |
| 785 | Abdominal pain | Symptoms | 1.01 | 1 – 1.02 | 0.0583 | 40170 | 302301 | exclusion | phecode |
| 788 | Syncope and collapse | Symptoms | 1.02 | 0.997 – 1.04 | 0.0984 | 9112 | 91099 | exclusion | phecode |
| 789 | Nausea and vomiting | Symptoms | 1.03 | 1.01 – 1.05 | 0.00749 | 11612 | 116110 | exclusion | phecode |
| 790 | Nonspecific findings on examination of blood | Symptoms | 0.89 | 0.743 – 1.06 | 0.196 | 150 | 1500 | exclusion | phecode |
| 791 | Gangrene | Symptoms | 0.911 | 0.831 – 0.998 | 0.0451 | 553 | 5530 | exclusion | phecode |
| 792 |
Abnormal Papanicolaou smear of cervix andAbnormal Papanicolaou smear of cervix and cervical HPV
|
Symptoms | 1.12 | 0.904 – 1.39 | 0.287 | 98 | 966 | exclusion | phecode |
| 793 |
Nonspecific abnormal findings on radiologicalNonspecific abnormal findings on radiological and other examination of musculoskeletal system
|
Symptoms | 0.939 | 0.777 – 1.13 | 0.51 | 134 | 1340 | exclusion | phecode |
| 794 |
Abnormal results of other function studiesAbnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
|
Symptoms | 0.897 | 0.74 – 1.08 | 0.261 | 120 | 1200 | exclusion | phecode |
| 797 | Shock | Symptoms | 0.851 | 0.713 – 1.01 | 0.0684 | 156 | 1560 | exclusion | phecode |
| 797.1 | Cardiogenic shock | Symptoms | 0.885 | 0.714 – 1.09 | 0.252 | 102 | 1020 | exclusion | phecode |
| 798 | Malaise and fatigue | Symptoms | 1 | 0.964 – 1.04 | 0.979 | 3424 | 34226 | exclusion | phecode |
| 798.1 | Chronic fatigue syndrome | Symptoms | 0.98 | 0.899 – 1.07 | 0.654 | 590 | 5900 | exclusion | phecode |
| 800 | Fracture of lower limb | Injuries & Poisonings | 1.01 | 0.981 – 1.03 | 0.656 | 7230 | 72297 | exclusion | phecode |
| 800.1 | Fracture of neck of femur | Injuries & Poisonings | 0.98 | 0.932 – 1.03 | 0.416 | 1813 | 18130 | exclusion | phecode |
| 800.2 | Fracture of unspecified part of femur | Injuries & Poisonings | 0.958 | 0.812 – 1.13 | 0.605 | 170 | 1700 | exclusion | phecode |
| 800.3 | Fracture of tibia and fibula | Injuries & Poisonings | 1.01 | 0.966 – 1.06 | 0.634 | 2156 | 21560 | exclusion | phecode |
| 800.4 | Fracture of patella | Injuries & Poisonings | 0.945 | 0.874 – 1.02 | 0.152 | 766 | 7660 | exclusion | phecode |
| 801 | Fracture of ankle and foot | Injuries & Poisonings | 1.04 | 0.994 – 1.08 | 0.0909 | 2333 | 23325 | exclusion | phecode |
| 801.1 | Fracture of foot | Injuries & Poisonings | 1.05 | 1 – 1.1 | 0.0506 | 1838 | 18375 | exclusion | phecode |
| 802 | Fracture of pelvis | Injuries & Poisonings | 1.02 | 0.941 – 1.1 | 0.646 | 722 | 7220 | exclusion | phecode |
| 803 | Fracture of upper limb | Injuries & Poisonings | 1.02 | 0.999 – 1.05 | 0.0605 | 8480 | 84788 | exclusion | phecode |
| 803.1 | Fracture of humerus | Injuries & Poisonings | 1.03 | 0.979 – 1.09 | 0.245 | 1685 | 16840 | exclusion | phecode |
| 803.2 | Fracture of radius and ulna | Injuries & Poisonings | 1.02 | 0.993 – 1.05 | 0.133 | 5214 | 52138 | exclusion | phecode |
| 803.3 | Fracture of clavicle or scapula | Injuries & Poisonings | 1.03 | 0.975 – 1.09 | 0.295 | 1518 | 15180 | exclusion | phecode |
| 804 | Fracture of hand or wrist | Injuries & Poisonings | 0.954 | 0.919 – 0.989 | 0.0114 | 3349 | 33490 | exclusion | phecode |
| 805 |
Fracture of vertebral column without mention ofFracture of vertebral column without mention of spinal cord injury
|
Injuries & Poisonings | 0.998 | 0.942 – 1.06 | 0.95 | 1359 | 13590 | exclusion | phecode |
| 807 | Fracture of ribs | Injuries & Poisonings | 1.07 | 0.988 – 1.15 | 0.0975 | 778 | 7780 | exclusion | phecode |
| 809 | Fracture of unspecified bones | Injuries & Poisonings | 1.03 | 0.973 – 1.09 | 0.302 | 1306 | 13060 | exclusion | phecode |
| 817 | Concussion | Injuries & Poisonings | 1.18 | 1.04 – 1.35 | 0.0116 | 245 | 2450 | exclusion | phecode |
| 818 | Intracranial hemorrhage (injury) | Injuries & Poisonings | 0.989 | 0.901 – 1.08 | 0.812 | 526 | 5260 | exclusion | phecode |
| 819 |
Skull and face fracture and other intercranialSkull and face fracture and other intercranial injury
|
Injuries & Poisonings | 1.05 | 1.01 – 1.09 | 0.0154 | 2967 | 29665 | exclusion | phecode |
| 823 | Torus fracture | Injuries & Poisonings | 1.01 | 0.959 – 1.06 | 0.727 | 1676 | 16752 | exclusion | phecode |
| 830 | Dislocation | Injuries & Poisonings | 0.995 | 0.95 – 1.04 | 0.836 | 2092 | 20914 | exclusion | phecode |
| 835 | Internal derangement of knee | Injuries & Poisonings | 1.01 | 0.995 – 1.03 | 0.183 | 15259 | 152537 | exclusion | phecode |
| 836 | Traumatic arthropathy | Injuries & Poisonings | 1.02 | 0.928 – 1.11 | 0.711 | 527 | 5270 | exclusion | phecode |
| 840 | Sprains and strains | Injuries & Poisonings | 1.04 | 0.943 – 1.14 | 0.455 | 496 | 4960 | exclusion | phecode |
| 850 | Hemorrhage or hematoma complicating a procedure | Injuries & Poisonings | 1.06 | 1.02 – 1.09 | 0.000294 | 5327 | 53270 | exclusion | phecode |
| 851 |
Complications of transplants and reattachedComplications of transplants and reattached limbs
|
Injuries & Poisonings | 0.945 | 0.79 – 1.13 | 0.528 | 159 | 1590 | exclusion | phecode |
| 853 | Complication of colostomy or enterostomy | Injuries & Poisonings | 0.977 | 0.886 – 1.07 | 0.628 | 503 | 5030 | exclusion | phecode |
| 854 |
Complications of cardiac/vascular deviceComplications of cardiac/vascular device, implant, and graft
|
Injuries & Poisonings | 0.999 | 0.95 – 1.05 | 0.957 | 1830 | 18300 | exclusion | phecode |
| 857 |
Mechanical complication of unspecifiedMechanical complication of unspecified genitourinary device, implant, and graft
|
Injuries & Poisonings | 1.03 | 0.968 – 1.09 | 0.366 | 1246 | 12460 | exclusion | phecode |
| 858 | Complication of internal orthopedic device | Injuries & Poisonings | 1.03 | 0.989 – 1.07 | 0.164 | 3163 | 31630 | exclusion | phecode |
| 859 |
Complication due to other implant and internalComplication due to other implant and internal device
|
Injuries & Poisonings | 1.04 | 0.998 – 1.08 | 0.06 | 3268 | 32680 | exclusion | phecode |
| 860 | Bone marrow or stem cell transplant | Neoplasms | 0.949 | 0.741 – 1.21 | 0.673 | 80 | 800 | exclusion | phecode |
| 870 | Open wounds of head; neck; and trunk | Injuries & Poisonings | 1.03 | 0.991 – 1.06 | 0.15 | 3836 | 38342 | exclusion | phecode |
| 870.1 | Open wound or laceration of eye or eyelid | Injuries & Poisonings | 1 | 0.882 – 1.14 | 0.959 | 270 | 2700 | exclusion | phecode |
| 870.2 | Open wound of ear | Injuries & Poisonings | 1.02 | 0.875 – 1.18 | 0.805 | 195 | 1950 | exclusion | phecode |
| 870.3 | Other open wound of head and face | Injuries & Poisonings | 1.02 | 0.984 – 1.06 | 0.242 | 2915 | 29141 | exclusion | phecode |
| 870.4 | Open wound of nose and sinus | Injuries & Poisonings | 0.989 | 0.856 – 1.14 | 0.876 | 220 | 2200 | exclusion | phecode |
| 870.6 | Open wound of neck | Injuries & Poisonings | 0.976 | 0.866 – 1.1 | 0.681 | 313 | 3130 | exclusion | phecode |
| 871 | Open wounds of extremities | Injuries & Poisonings | 0.973 | 0.942 – 1.01 | 0.0984 | 4216 | 42160 | exclusion | phecode |
| 871.1 | Open wound of hand except finger(s) | Injuries & Poisonings | 1.01 | 0.755 – 1.33 | 0.964 | 53 | 530 | exclusion | phecode |
| 871.2 | Open wound of finger(s) | Injuries & Poisonings | 0.834 | 0.665 – 1.04 | 0.108 | 91 | 910 | exclusion | phecode |
| 871.3 | Open wound of foot except toe(s) alone | Injuries & Poisonings | 0.978 | 0.833 – 1.15 | 0.779 | 179 | 1790 | exclusion | phecode |
| 872 | Traumatic amputation | Injuries & Poisonings | 0.955 | 0.865 – 1.05 | 0.355 | 476 | 4760 | exclusion | phecode |
| 873 | Broken tooth | Injuries & Poisonings | 0.96 | 0.835 – 1.1 | 0.56 | 229 | 2290 | exclusion | phecode |
| 874 | Complication of amputation stump | Injuries & Poisonings | 1.01 | 0.856 – 1.18 | 0.935 | 172 | 1720 | exclusion | phecode |
| 905 |
Late effects of musculoskeletal and connectiveLate effects of musculoskeletal and connective tissue injuries
|
Injuries & Poisonings | 0.945 | 0.799 – 1.12 | 0.504 | 158 | 1580 | exclusion | phecode |
| 907 | Injuries to the nervous system | Injuries & Poisonings | 0.997 | 0.941 – 1.06 | 0.932 | 1315 | 13150 | exclusion | phecode |
| 915 | Superficial injury without mention of infection | Injuries & Poisonings | 1.04 | 1.01 – 1.07 | 0.0228 | 4278 | 42778 | exclusion | phecode |
| 916 | Contusion | Injuries & Poisonings | 1.04 | 0.982 – 1.1 | 0.191 | 1484 | 14840 | exclusion | phecode |
| 930 | Allergic reaction to food | Injuries & Poisonings | 0.94 | 0.803 – 1.1 | 0.439 | 183 | 1830 | exclusion | phecode |
| 938 | Dermatitis due to solar radiation | Injuries & Poisonings | 1.28 | 1.13 – 1.44 | 6.09e-05 | 390 | 3900 | exclusion | phecode |
| 938.2 | Chronic dermatitis due to solar radiation | Injuries & Poisonings | 1.33 | 1.14 – 1.55 | 0.000256 | 253 | 2530 | exclusion | phecode |
| 939 |
Atopic/contact dermatitis due to other orAtopic/contact dermatitis due to other or unspecified
|
Dermatologic | 1.01 | 0.964 – 1.06 | 0.691 | 2105 | 21050 | exclusion | phecode |
| 941 | Adverse reaction to serum or vaccine | Injuries & Poisonings | 0.893 | 0.77 – 1.03 | 0.13 | 225 | 2250 | exclusion | phecode |
| 942 | Infusion and transfusion reaction | Injuries & Poisonings | 0.902 | 0.727 – 1.11 | 0.338 | 104 | 1040 | exclusion | phecode |
| 946 | Anaphylactic shock NOS | Injuries & Poisonings | 1.06 | 0.972 – 1.16 | 0.182 | 551 | 5510 | exclusion | phecode |
| 947 | Urticaria | Injuries & Poisonings | 1.02 | 0.914 – 1.14 | 0.728 | 373 | 3730 | exclusion | phecode |
| 949 | Allergies, other | Injuries & Poisonings | 1.13 | 1.02 – 1.25 | 0.022 | 399 | 3990 | exclusion | phecode |
| 952 |
Spinal cord injury without evidence of spinalSpinal cord injury without evidence of spinal bone injury
|
Injuries & Poisonings | 1.09 | 0.983 – 1.21 | 0.0995 | 423 | 4230 | exclusion | phecode |
| 957 | Injury to other and unspecified nerves | Injuries & Poisonings | 0.981 | 0.862 – 1.12 | 0.77 | 270 | 2700 | exclusion | phecode |
| 958 |
Certain early complications of trauma orCertain early complications of trauma or procedure
|
Injuries & Poisonings | 0.951 | 0.864 – 1.05 | 0.295 | 497 | 4970 | exclusion | phecode |
| 958.1 | Postoperative shock | Injuries & Poisonings | 0.989 | 0.744 – 1.31 | 0.937 | 56 | 560 | exclusion | phecode |
| 958.2 | Traumatic and surgical subcutaneous emphysema | Injuries & Poisonings | 0.842 | 0.653 – 1.08 | 0.173 | 74 | 740 | exclusion | phecode |
| 960 | Poisoning by antibiotics | Injuries & Poisonings | 1.01 | 0.99 – 1.02 | 0.454 | 18183 | 181830 | exclusion | phecode |
| 960.2 | Allergy/adverse effect of penicillin | Injuries & Poisonings | 1 | 0.987 – 1.02 | 0.657 | 15871 | 158710 | exclusion | phecode |
| 961 | Poisoning by other anti-infectives | Injuries & Poisonings | 1.02 | 0.921 – 1.13 | 0.685 | 420 | 4200 | exclusion | phecode |
| 962 | Poisoning by hormones and synthetic substitutes | Injuries & Poisonings | 1.05 | 0.937 – 1.16 | 0.422 | 382 | 3820 | exclusion | phecode |
| 962.3 |
Hormones and synthetic substitutes causingHormones and synthetic substitutes causing adverse effects in therapeutic use
|
Injuries & Poisonings | 1.05 | 0.94 – 1.17 | 0.378 | 364 | 3640 | exclusion | phecode |
| 963 | Poisoning by primarily systemic agents | Injuries & Poisonings | 1.03 | 0.898 – 1.19 | 0.64 | 226 | 2260 | exclusion | phecode |
| 964 |
Poisoning by agents primarily affecting bloodPoisoning by agents primarily affecting blood constituents
|
Injuries & Poisonings | 0.976 | 0.861 – 1.11 | 0.705 | 288 | 2880 | exclusion | phecode |
| 964.1 | Anticoagulants causing adverse effects | Injuries & Poisonings | 1 | 0.881 – 1.14 | 0.991 | 278 | 2780 | exclusion | phecode |
| 965 |
Poisoning by analgesics, antipyretics, andPoisoning by analgesics, antipyretics, and antirheumatics
|
Injuries & Poisonings | 0.997 | 0.97 – 1.02 | 0.83 | 6135 | 61345 | exclusion | phecode |
| 965.1 |
Opiates and related narcotics causing adverseOpiates and related narcotics causing adverse effects in therapeutic use
|
Injuries & Poisonings | 1.07 | 0.961 – 1.19 | 0.212 | 392 | 3920 | exclusion | phecode |
| 965.2 |
Antirheumatics causing adverse effects inAntirheumatics causing adverse effects in therapeutic use
|
Injuries & Poisonings | 1.06 | 0.962 – 1.16 | 0.242 | 477 | 4765 | exclusion | phecode |
| 965.3 |
Salicylates causing adverse effects inSalicylates causing adverse effects in therapeutic use
|
Injuries & Poisonings | 1.07 | 0.967 – 1.19 | 0.178 | 403 | 4025 | exclusion | phecode |
| 966 |
Poisoning by anticonvulsants andPoisoning by anticonvulsants and anti-Parkinsonism drugs
|
Injuries & Poisonings | 0.988 | 0.899 – 1.08 | 0.793 | 513 | 5130 | exclusion | phecode |
| 967 |
Adverse effects of sedatives or other centralAdverse effects of sedatives or other central nervous system depressants and anesthetics
|
Injuries & Poisonings | 1.06 | 0.969 – 1.15 | 0.207 | 590 | 5900 | exclusion | phecode |
| 969 | Poisoning by psychotropic agents | Injuries & Poisonings | 1.01 | 0.962 – 1.06 | 0.715 | 1960 | 19589 | exclusion | phecode |
| 971 |
Poisoning by drugs primarily affecting thePoisoning by drugs primarily affecting the autonomic nervous system
|
Injuries & Poisonings | 0.988 | 0.849 – 1.15 | 0.879 | 192 | 1920 | exclusion | phecode |
| 972 |
Poisoning by agents primarily affecting thePoisoning by agents primarily affecting the cardiovascular system
|
Injuries & Poisonings | 1.05 | 0.922 – 1.19 | 0.475 | 282 | 2820 | exclusion | phecode |
| 972.6 | Antihypertensive agents causing adverse effects | Injuries & Poisonings | 0.973 | 0.77 – 1.22 | 0.812 | 85 | 850 | exclusion | phecode |
| 973 |
Poisoning by agents primarily affecting thePoisoning by agents primarily affecting the gastrointestinal system
|
Injuries & Poisonings | 1.13 | 0.925 – 1.38 | 0.223 | 108 | 1080 | exclusion | phecode |
| 974 |
Poisoning by water, mineral, and uric acidPoisoning by water, mineral, and uric acid metabolism drugs
|
Injuries & Poisonings | 0.929 | 0.75 – 1.15 | 0.487 | 102 | 1020 | exclusion | phecode |
| 975 |
Poisoning by agents primarily acting on thePoisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
|
Injuries & Poisonings | 0.941 | 0.72 – 1.22 | 0.644 | 64 | 640 | exclusion | phecode |
| 976 |
Poisoning by agents primarily affecting skin &Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
|
Injuries & Poisonings | 1.2 | 0.9 – 1.59 | 0.207 | 58 | 580 | exclusion | phecode |
| 977 | Personal history of allergy to medicinal agents | Injuries & Poisonings | 1.1 | 0.955 – 1.26 | 0.188 | 235 | 2350 | exclusion | phecode |
| 979 | Adverse drug events and drug allergies | Injuries & Poisonings | 1.05 | 0.972 – 1.14 | 0.202 | 699 | 6983 | exclusion | phecode |
| 981 |
Toxic effect of (non-ethyl) alcohol andToxic effect of (non-ethyl) alcohol and petroleum and other solvents
|
Injuries & Poisonings | 0.947 | 0.816 – 1.1 | 0.475 | 201 | 2010 | exclusion | phecode |
| 986 | Toxic effect of carbon monoxide | Injuries & Poisonings | 1.09 | 0.856 – 1.39 | 0.469 | 73 | 730 | exclusion | phecode |
| 987 | Toxic effect of other gases, fumes, or vapors | Injuries & Poisonings | 1.34 | 1.09 – 1.64 | 0.00425 | 106 | 1060 | exclusion | phecode |
| 988 | Toxic effect of noxious substances eaten as food | Injuries & Poisonings | 0.77 | 0.626 – 0.943 | 0.0116 | 113 | 1130 | exclusion | phecode |
| 989 |
Toxic effect of other substances, chieflyToxic effect of other substances, chiefly nonmedicinal as to source
|
Injuries & Poisonings | 0.878 | 0.695 – 1.1 | 0.262 | 89 | 890 | exclusion | phecode |
| 990 | Effects radiation NOS | Injuries & Poisonings | 1.02 | 0.984 – 1.06 | 0.256 | 3122 | 31220 | exclusion | phecode |
| 994 | Sepsis and SIRS | Injuries & Poisonings | 0.98 | 0.943 – 1.02 | 0.304 | 3036 | 30360 | exclusion | phecode |
| 994.2 | Sepsis | Injuries & Poisonings | 0.98 | 0.943 – 1.02 | 0.304 | 3036 | 30360 | exclusion | phecode |