University of Michigan Center for Statistical 


QTDT - Online Reference

Abecasis, Cardon and Cookson, Am Journal Hum Genet 66:279-292 (2000)

If you haven't used QTDT before, please take a guided tour of the QTDT package. A Frequently Asked Questions page is also available.

Command Line Quick reference sheet with a summary of all QTDT command line options. Detailed descriptions of most of these options are available below.
Input Files QTDT requires matched data and pedigree files as input. An optional IBD information file is recommended for variance component analyses.
Association Model As well as the model of Abecasis (2000), the models of Allison (1997, TDTQ5), Rabinowitz (1997), Monks (1998) and Fulker (2000) are also supported.
Variance Components Optionally, variance components can be used to describe the similarities between individuals in a pedigree.
Permutations Asymptotic p-values can be misleading for non-normal data. This option employs a general permutation framework that allows for non-normal data or small samples.
Multiple Alleles Options for analysing microsatellites or haplotypes.
Twins Details of support for twin data within QTDT.
Additional Information Options for the analysis of SNP data and modelling imprinting. Brief description of output files.


University of Michigan | School of Public Health | Abecasis Lab