Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Colorectal cancer UK Biobank (UKB) PheWAS analysis

Colorectal cancer — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID prsweb-phecode153-crc-huyghe-pt-ukb-20200608Legacy P&TP&THuyghe JR et al. 2019

Evaluation cohort: UK Biobank (UKB).

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149 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 0.997 0.976 – 1.02 0.792 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.02 0.978 – 1.06 0.407 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.08 1 – 1.17 0.0498 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 0.941 0.878 – 1.01 0.0902 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 0.868 0.658 – 1.15 0.318 55 550 all phecode
010 Tuberculosis Infectious Diseases 1.11 0.945 – 1.3 0.206 166 1659 all phecode
038 Septicemia Infectious Diseases 1.01 0.979 – 1.04 0.52 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.06 0.989 – 1.14 0.0966 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.02 0.93 – 1.12 0.685 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 1.03 1.01 – 1.05 0.001 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.06 1.02 – 1.1 0.00258 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 1.07 1.02 – 1.12 0.00854 1641 16433 all phecode
041.4 E. coli Infectious Diseases 1.01 0.976 – 1.06 0.466 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 1.04 0.944 – 1.15 0.4 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.01 0.823 – 1.25 0.899 95 949 all phecode
054 Herpes simplex Infectious Diseases 0.874 0.758 – 1.01 0.066 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 0.987 0.907 – 1.07 0.759 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 1.13 0.888 – 1.44 0.321 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.01 0.853 – 1.2 0.898 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.01 0.894 – 1.15 0.83 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 1 0.883 – 1.13 0.994 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.08 0.979 – 1.2 0.123 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.984 0.83 – 1.17 0.853 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.961 0.793 – 1.16 0.681 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 0.977 0.915 – 1.04 0.473 1004 10036 all phecode
079 Viral infection Infectious Diseases 0.998 0.959 – 1.04 0.901 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 0.898 0.699 – 1.16 0.404 64 640 all phecode
080 Postoperative infection Infectious Diseases 1.04 1.01 – 1.08 0.00517 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.05 1.01 – 1.1 0.0177 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.909 0.718 – 1.15 0.426 71 709 all phecode
1000 Burns Injuries & Poisonings 1.02 0.935 – 1.11 0.692 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 0.975 0.919 – 1.03 0.395 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.03 0.999 – 1.06 0.0598 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.03 0.915 – 1.16 0.63 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 1.05 0.996 – 1.11 0.0675 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 1.02 0.893 – 1.15 0.816 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 1.04 0.913 – 1.17 0.589 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 0.958 0.898 – 1.02 0.192 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 1 0.981 – 1.03 0.795 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 1.01 0.984 – 1.04 0.426 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1 0.979 – 1.02 0.968 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 1.06 0.871 – 1.28 0.571 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.03 0.914 – 1.15 0.654 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.09 0.843 – 1.42 0.501 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 1 0.973 – 1.04 0.807 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1 0.985 – 1.02 0.843 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.961 0.851 – 1.08 0.52 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 0.947 0.837 – 1.07 0.385 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.23 0.97 – 1.56 0.0875 74 756 all phecode
110.12 Althete's foot Infectious Diseases 0.893 0.755 – 1.06 0.187 141 1410 all phecode
112 Candidiasis Infectious Diseases 1.04 0.99 – 1.08 0.131 2126 21275 all phecode
117 Mycoses Infectious Diseases 0.922 0.814 – 1.04 0.201 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 0.91 0.778 – 1.06 0.238 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 0.964 0.771 – 1.21 0.749 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 1 0.785 – 1.29 0.971 69 689 all phecode
134 Helminthiases Infectious Diseases 1.01 0.835 – 1.21 0.941 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1.05 0.862 – 1.28 0.631 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.05 0.906 – 1.21 0.531 205 2050 all phecode
145 Cancer of mouth Neoplasms 0.974 0.898 – 1.06 0.522 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 1 0.892 – 1.12 0.976 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.01 0.829 – 1.23 0.926 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 0.872 0.664 – 1.15 0.324 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1 0.925 – 1.09 0.956 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 0.979 0.861 – 1.11 0.743 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 1 0.885 – 1.14 0.958 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 1.12 0.857 – 1.48 0.397 57 570 all phecode
150 Cancer of esophagus Neoplasms 1.02 0.947 – 1.1 0.602 762 7630 all phecode
151 Cancer of stomach Neoplasms 1.03 0.948 – 1.13 0.462 569 5696 all phecode
153 Colorectal cancer Neoplasms 1.55 1.5 – 1.59 1.72e-166 4580 45799 all phecode
153.2 Colon cancer Neoplasms 1.56 1.5 – 1.62 3.45e-118 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.53 1.47 – 1.6 5.56e-77 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1 0.904 – 1.11 0.988 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.999 0.852 – 1.17 0.991 158 1580 all phecode
157 Pancreatic cancer Neoplasms 1.13 1.04 – 1.22 0.00359 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.41 1.32 – 1.5 1.71e-25 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.36 1.32 – 1.4 2.72e-104 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.12 0.966 – 1.3 0.135 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.13 0.981 – 1.3 0.0907 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.995 0.857 – 1.15 0.945 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 0.928 0.717 – 1.2 0.573 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 0.987 0.949 – 1.03 0.496 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 0.98 0.938 – 1.02 0.378 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.948 0.86 – 1.05 0.291 437 4364 all phecode
170.1 Bone cancer Neoplasms 1 0.844 – 1.19 0.962 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 0.954 0.852 – 1.07 0.411 331 3303 all phecode
172 Skin cancer Neoplasms 1 0.986 – 1.02 0.681 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.999 0.96 – 1.04 0.946 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 1 0.961 – 1.04 0.994 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1 0.984 – 1.02 0.725 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.02 0.937 – 1.1 0.703 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.988 0.851 – 1.15 0.879 181 1818 all phecode
174 Breast cancer Neoplasms 1.04 1.02 – 1.06 0.000104 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 1.03 1.02 – 1.05 0.000291 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.03 1.01 – 1.05 0.000576 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.971 0.8 – 1.18 0.766 115 1148 all phecode
175 Acquired absence of breast Neoplasms 0.997 0.956 – 1.04 0.87 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 0.994 0.951 – 1.04 0.804 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 1.04 0.917 – 1.17 0.561 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.985 0.941 – 1.03 0.513 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 0.993 0.937 – 1.05 0.808 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 1.03 0.976 – 1.09 0.272 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.02 0.958 – 1.09 0.485 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.03 0.963 – 1.1 0.38 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.06 0.939 – 1.19 0.359 305 3049 all phecode
185 Cancer of prostate Neoplasms 1.02 0.993 – 1.05 0.155 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 1.02 0.926 – 1.12 0.696 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.23 0.962 – 1.57 0.0993 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.982 0.869 – 1.11 0.771 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.02 0.844 – 1.24 0.81 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.01 0.974 – 1.04 0.729 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.05 0.984 – 1.12 0.144 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.05 0.987 – 1.12 0.118 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.16 0.906 – 1.48 0.24 66 660 all phecode
189.2 Cancer of bladder Neoplasms 0.988 0.947 – 1.03 0.573 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.98 0.937 – 1.02 0.373 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.03 0.87 – 1.22 0.721 144 1439 all phecode
190 Cancer of eye Neoplasms 1.06 0.907 – 1.24 0.468 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.924 0.854 – 0.999 0.0479 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 0.912 0.837 – 0.995 0.0372 566 5650 all phecode
191.11 Cancer of brain Neoplasms 0.931 0.851 – 1.02 0.115 525 5240 all phecode
193 Thyroid cancer Neoplasms 0.962 0.861 – 1.07 0.494 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 1.09 0.89 – 1.34 0.395 95 949 all phecode
195 Cancer, suspected or other Neoplasms 1.09 1.08 – 1.11 1.18e-28 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.1 1.08 – 1.12 1.8e-29 16267 159497 all phecode
197 Chemotherapy Neoplasms 1.04 1.03 – 1.05 4.73e-08 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 1.09 1.06 – 1.11 1.09e-14 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.09 1.06 – 1.12 6.47e-10 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.1 1.05 – 1.14 3.64e-05 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.09 1.04 – 1.15 0.000753 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.14 1.09 – 1.18 2.22e-10 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.968 0.902 – 1.04 0.369 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 0.994 0.951 – 1.04 0.803 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.999 0.858 – 1.16 0.994 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.03 0.976 – 1.09 0.272 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 1.02 0.831 – 1.25 0.853 95 950 all phecode
200 Myeloproliferative disease Neoplasms 1.01 0.946 – 1.08 0.774 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 1 0.906 – 1.11 0.938 387 3867 all phecode
201 Hodgkin's disease Neoplasms 0.894 0.788 – 1.01 0.0797 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.01 0.968 – 1.05 0.644 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.03 0.98 – 1.08 0.249 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 1.13 1.02 – 1.26 0.0227 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 1.03 0.947 – 1.12 0.48 581 5824 all phecode
204 Leukemia Neoplasms 0.961 0.914 – 1.01 0.12 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 0.98 0.9 – 1.07 0.642 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.793 0.605 – 1.04 0.0916 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.994 0.908 – 1.09 0.889 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 0.891 0.81 – 0.981 0.0189 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 0.863 0.77 – 0.968 0.0122 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.993 0.84 – 1.17 0.933 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 1 0.917 – 1.09 0.998 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 1.32 1.3 – 1.34 2.12e-301 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.03 0.97 – 1.1 0.303 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.05 1.02 – 1.08 0.000716 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.998 0.894 – 1.11 0.97 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.03 0.917 – 1.16 0.618 318 3187 all phecode
214 Lipoma Neoplasms 1.02 0.991 – 1.04 0.206 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.01 0.98 – 1.04 0.497 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.04 0.974 – 1.1 0.268 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 1.01 0.983 – 1.03 0.623 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.05 0.967 – 1.14 0.253 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1.04 0.956 – 1.13 0.365 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 0.995 0.975 – 1.02 0.614 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 0.997 0.977 – 1.02 0.786 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.01 0.911 – 1.13 0.809 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 1.02 0.966 – 1.08 0.489 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.03 0.894 – 1.17 0.722 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 1.05 0.897 – 1.24 0.52 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.996 0.854 – 1.16 0.961 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 0.969 0.804 – 1.17 0.74 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.02 0.794 – 1.32 0.854 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.978 0.909 – 1.05 0.539 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.972 0.902 – 1.05 0.449 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.17 0.899 – 1.52 0.244 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.11 0.979 – 1.26 0.105 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.03 0.963 – 1.11 0.375 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.02 0.877 – 1.18 0.811 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.07 0.961 – 1.19 0.222 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.977 0.87 – 1.1 0.691 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.06 1.01 – 1.12 0.0263 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.03 0.985 – 1.07 0.212 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.957 0.88 – 1.04 0.31 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1 0.94 – 1.06 0.995 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.03 0.933 – 1.13 0.587 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.997 0.922 – 1.08 0.941 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.06 1.01 – 1.11 0.013 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 1.12 1.01 – 1.23 0.0259 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.06 0.861 – 1.31 0.569 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 0.99 0.832 – 1.18 0.909 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 1.01 0.992 – 1.03 0.292 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.02 0.961 – 1.09 0.497 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.919 0.751 – 1.12 0.412 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.01 0.992 – 1.03 0.276 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 1.06 0.943 – 1.2 0.313 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.07 0.937 – 1.23 0.306 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.02 0.888 – 1.18 0.76 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 0.981 0.885 – 1.09 0.707 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 1.01 0.999 – 1.03 0.0685 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.03 0.995 – 1.08 0.0914 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.971 0.855 – 1.1 0.655 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.85 0.668 – 1.08 0.187 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.08 0.982 – 1.19 0.112 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.02 0.868 – 1.2 0.819 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.01 0.997 – 1.03 0.109 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.756 0.622 – 0.919 0.00502 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.963 0.83 – 1.12 0.617 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.06 0.988 – 1.13 0.11 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 0.939 0.857 – 1.03 0.174 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.02 0.944 – 1.11 0.594 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.11 0.981 – 1.27 0.0964 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.969 0.876 – 1.07 0.535 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.06 0.89 – 1.26 0.514 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.982 0.881 – 1.1 0.748 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.05 0.988 – 1.11 0.127 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.01 0.943 – 1.08 0.82 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.07 0.997 – 1.15 0.0619 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.07 0.99 – 1.15 0.0891 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.06 0.897 – 1.26 0.475 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.02 0.947 – 1.11 0.543 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.986 0.851 – 1.14 0.854 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.03 0.838 – 1.25 0.808 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.05 0.921 – 1.19 0.494 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.964 0.778 – 1.19 0.739 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.04 0.883 – 1.22 0.664 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.997 0.92 – 1.08 0.95 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1 0.858 – 1.16 0.997 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.93 0.757 – 1.14 0.486 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.1 0.869 – 1.38 0.441 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.918 0.824 – 1.02 0.122 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.915 0.821 – 1.02 0.109 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 0.977 0.855 – 1.12 0.733 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.01 0.872 – 1.16 0.926 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 0.878 0.747 – 1.03 0.113 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.896 0.759 – 1.06 0.192 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.953 0.781 – 1.16 0.634 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 0.943 0.8 – 1.11 0.487 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.915 0.79 – 1.06 0.235 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 0.988 0.751 – 1.3 0.934 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 0.971 0.905 – 1.04 0.41 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.05 0.991 – 1.12 0.0986 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.03 0.952 – 1.11 0.498 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.08 0.977 – 1.19 0.137 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.881 0.697 – 1.11 0.288 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.977 0.86 – 1.11 0.724 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 1.11 0.992 – 1.24 0.0689 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.956 0.851 – 1.07 0.447 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.93 0.82 – 1.05 0.254 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 0.899 0.777 – 1.04 0.154 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.06 0.87 – 1.28 0.578 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 0.956 0.742 – 1.23 0.726 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.976 0.83 – 1.15 0.765 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.963 0.81 – 1.14 0.665 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1 0.989 – 1.01 0.984 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1 0.989 – 1.01 0.975 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1 0.989 – 1.01 0.866 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.888 0.685 – 1.15 0.373 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.978 0.834 – 1.15 0.783 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.958 0.835 – 1.1 0.545 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.965 0.933 – 0.999 0.0413 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 0.97 0.935 – 1.01 0.1 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.883 0.728 – 1.07 0.204 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.97 0.893 – 1.05 0.469 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.959 0.88 – 1.05 0.341 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.04 0.996 – 1.09 0.0754 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 1 0.925 – 1.09 0.957 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.02 0.912 – 1.13 0.778 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.07 1.01 – 1.13 0.0282 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.09 0.933 – 1.27 0.283 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.02 0.996 – 1.04 0.108 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.02 0.988 – 1.05 0.212 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.998 0.872 – 1.14 0.972 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.03 0.985 – 1.08 0.178 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.02 0.952 – 1.08 0.635 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.02 0.966 – 1.08 0.474 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.02 0.96 – 1.08 0.52 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 1.02 0.956 – 1.08 0.57 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 1.11 0.91 – 1.35 0.306 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.02 0.978 – 1.06 0.409 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 1.09 0.992 – 1.21 0.072 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 0.857 0.714 – 1.03 0.0964 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.01 0.947 – 1.09 0.695 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.963 0.864 – 1.07 0.497 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.951 0.83 – 1.09 0.467 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.06 0.792 – 1.41 0.714 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.01 0.987 – 1.03 0.54 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 1.01 0.985 – 1.03 0.609 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 1.01 0.812 – 1.26 0.922 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.14 0.898 – 1.44 0.285 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.11 0.975 – 1.27 0.115 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 1.06 0.922 – 1.23 0.393 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.11 0.929 – 1.32 0.258 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.04 0.916 – 1.18 0.544 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 1.02 0.997 – 1.05 0.09 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.02 0.996 – 1.05 0.103 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.01 0.915 – 1.11 0.882 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 0.999 0.94 – 1.06 0.978 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 1.01 0.951 – 1.08 0.704 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 1.03 0.956 – 1.11 0.445 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.949 0.816 – 1.1 0.495 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 1.05 0.895 – 1.22 0.576 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 0.858 0.655 – 1.12 0.264 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.01 0.851 – 1.19 0.936 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1 0.772 – 1.3 0.995 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.996 0.802 – 1.24 0.968 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 0.975 0.816 – 1.16 0.781 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.05 0.855 – 1.28 0.661 103 1059 all phecode
284 Aplastic anemia Hematopoietic 1.01 0.917 – 1.11 0.831 435 4357 all phecode
285 Other anemias Hematopoietic 1.02 1 – 1.04 0.0444 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.09 0.961 – 1.23 0.182 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.07 0.989 – 1.16 0.0934 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.05 0.948 – 1.16 0.363 414 4147 all phecode
286 Coagulation defects Hematopoietic 0.988 0.923 – 1.06 0.733 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 0.961 0.874 – 1.06 0.421 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 0.973 0.792 – 1.2 0.796 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.94 0.834 – 1.06 0.309 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.07 0.834 – 1.39 0.577 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.914 0.739 – 1.13 0.41 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.01 0.909 – 1.12 0.85 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.998 0.949 – 1.05 0.94 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.16 0.966 – 1.39 0.111 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 1.15 0.867 – 1.53 0.333 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 0.992 0.942 – 1.05 0.775 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.03 0.932 – 1.14 0.57 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.05 0.826 – 1.34 0.679 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 1 0.97 – 1.04 0.861 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 1.01 0.974 – 1.05 0.588 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 1.01 0.974 – 1.05 0.578 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 0.905 0.71 – 1.15 0.42 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.975 0.909 – 1.04 0.468 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.992 0.878 – 1.12 0.892 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 0.999 0.96 – 1.04 0.965 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 1.01 0.921 – 1.1 0.88 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.04 0.921 – 1.17 0.529 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 0.83 0.663 – 1.04 0.104 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.01 0.96 – 1.05 0.804 1929 19281 all phecode
290.1 Dementias Mental Disorders 0.987 0.925 – 1.05 0.681 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 0.959 0.869 – 1.06 0.411 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 1.07 0.921 – 1.23 0.388 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.06 0.975 – 1.15 0.179 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.05 0.831 – 1.33 0.683 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1 0.931 – 1.07 0.991 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.13 0.949 – 1.36 0.166 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.945 0.839 – 1.06 0.352 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 0.999 0.907 – 1.1 0.986 436 4376 all phecode
292 Neurological disorders Mental Disorders 1.02 0.99 – 1.05 0.18 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.02 0.966 – 1.07 0.492 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.993 0.856 – 1.15 0.928 190 1907 all phecode
292.3 Memory loss Mental Disorders 1.02 0.939 – 1.1 0.696 696 6978 all phecode
292.4 Altered mental status Mental Disorders 1.03 0.987 – 1.08 0.165 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 0.974 0.867 – 1.09 0.651 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 1.03 0.984 – 1.08 0.202 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.04 0.968 – 1.11 0.306 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.11 1.04 – 1.19 0.00309 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 1.13 1.03 – 1.23 0.00635 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 1.05 0.898 – 1.22 0.555 178 1780 all phecode
295.3 Psychosis Mental Disorders 1.03 0.88 – 1.2 0.718 169 1710 all phecode
296 Mood disorders Mental Disorders 1.01 0.99 – 1.03 0.346 12372 123822 all phecode
296.1 Bipolar Mental Disorders 1.02 0.958 – 1.09 0.539 1059 10599 all phecode
296.2 Depression Mental Disorders 1.01 0.989 – 1.03 0.411 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 1 0.898 – 1.11 0.989 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.08 0.96 – 1.21 0.201 311 3070 all phecode
300 Anxiety disorders Mental Disorders 1.01 0.98 – 1.03 0.682 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 1.01 0.985 – 1.04 0.421 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 0.967 0.82 – 1.14 0.685 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.999 0.924 – 1.08 0.983 707 7065 all phecode
300.13 Phobia Mental Disorders 1.01 0.922 – 1.11 0.812 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.19 0.998 – 1.43 0.0533 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 0.919 0.7 – 1.21 0.54 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 0.954 0.798 – 1.14 0.608 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.887 0.734 – 1.07 0.215 113 1129 all phecode
301 Personality disorders Mental Disorders 0.93 0.83 – 1.04 0.216 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.927 0.766 – 1.12 0.436 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 1.18 1.05 – 1.34 0.00758 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.08 0.986 – 1.19 0.0949 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 1.09 0.979 – 1.22 0.115 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 1.05 0.877 – 1.27 0.578 123 1229 all phecode
304 Adjustment reaction Mental Disorders 0.959 0.851 – 1.08 0.498 293 2936 all phecode
305.2 Eating disorder Mental Disorders 1.03 0.835 – 1.28 0.758 90 900 all phecode
306 Other mental disorder Mental Disorders 1 0.99 – 1.01 0.75 28056 230087 all phecode
306.9 Tension headache Mental Disorders 1.05 0.932 – 1.17 0.447 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 1.31 1.04 – 1.64 0.0208 76 770 all phecode
313.3 Autism Mental Disorders 1.4 1.07 – 1.83 0.0135 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 1.01 0.906 – 1.13 0.854 351 3517 all phecode
315.1 Learning disorder Mental Disorders 1.1 0.934 – 1.3 0.254 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 1.06 0.853 – 1.31 0.606 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 1.02 0.996 – 1.05 0.0949 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.06 0.817 – 1.38 0.66 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 1.01 0.992 – 1.03 0.296 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 1 0.983 – 1.03 0.697 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.02 0.948 – 1.09 0.633 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 1.01 0.991 – 1.02 0.418 19359 185465 all phecode
320 Meningitis Neurological 1.08 0.979 – 1.19 0.126 444 4447 all phecode
323 Encephalitis Neurological 1.02 0.913 – 1.14 0.728 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 1.05 0.831 – 1.34 0.666 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 0.995 0.884 – 1.12 0.939 292 2916 all phecode
327 Sleep disorders Neurological 0.969 0.913 – 1.03 0.306 1164 11659 all phecode
327.3 Sleep apnea Neurological 1.01 0.981 – 1.04 0.449 4428 44318 all phecode
327.4 Insomnia Neurological 0.982 0.839 – 1.15 0.825 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 0.993 0.834 – 1.18 0.939 136 1390 all phecode
331 Other cerebral degenerations Neurological 0.989 0.931 – 1.05 0.708 1142 11416 all phecode
331.1 Hydrocephalus Neurological 0.969 0.885 – 1.06 0.5 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 0.976 0.885 – 1.08 0.633 430 4298 all phecode
332 Parkinson's disease Neurological 0.988 0.93 – 1.05 0.7 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.953 0.89 – 1.02 0.17 894 8954 all phecode
333.1 Essential tremor Neurological 0.954 0.829 – 1.1 0.516 216 2157 all phecode
333.2 Myoclonus Neurological 0.904 0.737 – 1.11 0.337 96 958 all phecode
333.4 Torsion dystonia Neurological 0.895 0.786 – 1.02 0.096 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 0.951 0.906 – 0.998 0.0393 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 0.877 0.732 – 1.05 0.153 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 0.903 0.789 – 1.03 0.134 245 2446 all phecode
335 Multiple sclerosis Neurological 0.892 0.843 – 0.944 6.67e-05 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 1.03 0.907 – 1.17 0.643 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.07 0.84 – 1.36 0.586 72 719 all phecode
338 Pain Neurological 0.973 0.904 – 1.05 0.478 768 7692 all phecode
338.1 Acute pain Neurological 0.968 0.872 – 1.07 0.542 394 3937 all phecode
338.2 Chronic pain Neurological 0.967 0.871 – 1.07 0.533 380 3817 all phecode
339 Other headache syndromes Neurological 1 0.982 – 1.03 0.691 7819 78241 all phecode
340 Migraine Neurological 0.992 0.954 – 1.03 0.668 2860 28602 all phecode
340.1 Migrain with aura Neurological 0.967 0.841 – 1.11 0.637 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.993 0.874 – 1.13 0.919 252 2535 all phecode
342 Hemiplegia Neurological 0.957 0.908 – 1.01 0.106 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 1.03 0.872 – 1.22 0.713 145 1450 all phecode
344 Other paralytic syndromes Neurological 1.03 0.946 – 1.11 0.533 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.974 0.946 – 1 0.0708 5023 50270 all phecode
345.1 Epilepsy Neurological 0.954 0.89 – 1.02 0.187 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 1 0.91 – 1.11 0.94 439 4385 all phecode
345.12 Partial epilepsy Neurological 1.02 0.9 – 1.15 0.805 277 2776 all phecode
345.3 Convulsions Neurological 0.965 0.924 – 1.01 0.104 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.949 0.801 – 1.12 0.546 144 1438 all phecode
348 Other conditions of brain Neurological 0.963 0.895 – 1.04 0.319 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.03 0.912 – 1.17 0.607 268 2678 all phecode
348.4 Cerebral cysts Neurological 0.86 0.722 – 1.02 0.0904 133 1350 all phecode
348.7 Coma Neurological 1.01 0.902 – 1.12 0.92 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 0.959 0.842 – 1.09 0.523 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 1.07 0.965 – 1.19 0.198 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.02 0.91 – 1.14 0.77 342 3414 all phecode
350 Abnormal movement Neurological 1.05 1.01 – 1.09 0.0135 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 1.04 0.971 – 1.11 0.266 887 8852 all phecode
350.2 Abnormality of gait Neurological 1.05 0.998 – 1.11 0.0608 1596 15969 all phecode
350.3 Lack of coordination Neurological 1.07 0.967 – 1.19 0.182 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 1 0.767 – 1.31 0.994 54 540 all phecode
351 Other peripheral nerve disorders Neurological 0.986 0.968 – 1 0.126 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 1.01 0.953 – 1.06 0.795 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.971 0.883 – 1.07 0.547 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.01 0.938 – 1.08 0.886 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 1.01 0.949 – 1.07 0.772 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 1.02 0.836 – 1.23 0.871 114 1138 all phecode
353.2 Nerve root lesions Neurological 0.981 0.757 – 1.27 0.885 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.849 0.718 – 1 0.0568 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.03 0.972 – 1.09 0.338 1361 13648 all phecode
358 Myoneural disorders Neurological 1.01 0.872 – 1.16 0.941 211 2109 all phecode
358.1 Myasthenia gravis Neurological 0.984 0.85 – 1.14 0.826 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 1.03 0.938 – 1.14 0.514 465 4646 all phecode
359.1 Muscular dystrophies Neurological 0.98 0.814 – 1.18 0.828 122 1219 all phecode
359.2 Myopathy Neurological 1.04 0.928 – 1.16 0.525 360 3597 all phecode
360 Disorders of the globe Sense Organs 0.991 0.888 – 1.11 0.879 337 3367 all phecode
360.2 Progressive myopia Sense Organs 0.986 0.867 – 1.12 0.826 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 1 0.967 – 1.04 0.896 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.99 0.937 – 1.05 0.719 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 1.03 0.811 – 1.31 0.804 68 680 all phecode
362 Other retinal disorders Sense Organs 1 0.97 – 1.04 0.858 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.991 0.948 – 1.04 0.675 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.99 0.948 – 1.03 0.663 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.07 0.913 – 1.26 0.39 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 1 0.815 – 1.23 0.998 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.995 0.928 – 1.07 0.898 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 1.14 0.973 – 1.33 0.106 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.09 0.861 – 1.37 0.483 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.12 0.925 – 1.35 0.251 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.909 0.777 – 1.06 0.233 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 1.01 0.793 – 1.29 0.922 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.978 0.903 – 1.06 0.579 647 6485 all phecode
364.1 Corneal opacity Sense Organs 1.02 0.814 – 1.27 0.874 90 910 all phecode
364.2 Corneal edema Sense Organs 0.905 0.721 – 1.14 0.391 79 800 all phecode
364.4 Corneal degenerations Sense Organs 0.924 0.801 – 1.07 0.28 201 2017 all phecode
364.41 Keratoconus Sense Organs 0.97 0.777 – 1.21 0.79 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 1.01 0.885 – 1.16 0.845 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.962 0.789 – 1.17 0.701 100 1000 all phecode
365 Glaucoma Sense Organs 1.01 0.978 – 1.04 0.564 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 1.01 0.952 – 1.08 0.659 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 1.02 0.953 – 1.08 0.627 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.06 0.979 – 1.14 0.157 698 6996 all phecode
366 Cataract Sense Organs 0.99 0.976 – 1 0.186 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 0.983 0.768 – 1.26 0.891 69 700 all phecode
366.2 Senile cataract Sense Organs 1 0.978 – 1.02 0.998 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 0.797 0.653 – 0.973 0.0255 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.992 0.951 – 1.03 0.71 2408 24092 all phecode
367.1 Myopia Sense Organs 0.958 0.904 – 1.02 0.148 1251 12519 all phecode
367.2 Astigmatism Sense Organs 0.964 0.832 – 1.12 0.623 190 1899 all phecode
367.8 Hypermetropia Sense Organs 1.02 0.898 – 1.16 0.746 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 1.09 1.01 – 1.17 0.0312 719 7198 all phecode
368 Visual disturbances Sense Organs 0.987 0.95 – 1.02 0.481 2962 29648 all phecode
368.1 Amblyopia Sense Organs 1.09 0.995 – 1.19 0.0647 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.969 0.897 – 1.05 0.419 727 7288 all phecode
368.3 Anisometropia Sense Organs 0.997 0.848 – 1.17 0.972 154 1548 all phecode
368.4 Visual field defects Sense Organs 0.959 0.857 – 1.07 0.459 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 1.03 0.944 – 1.11 0.552 612 6115 all phecode
369 Infection of the eye Sense Organs 1.04 0.952 – 1.13 0.392 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 1.13 0.942 – 1.36 0.186 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.939 0.816 – 1.08 0.375 213 2128 all phecode
370 Keratitis Sense Organs 0.869 0.768 – 0.982 0.024 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 0.853 0.716 – 1.01 0.0726 141 1408 all phecode
371 Inflammation of the eye Sense Organs 0.976 0.94 – 1.01 0.197 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.93 0.846 – 1.02 0.131 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 0.962 0.922 – 1 0.0786 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 1.07 0.994 – 1.16 0.0695 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 1.02 0.992 – 1.05 0.175 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 1.01 0.948 – 1.08 0.764 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 1.01 0.965 – 1.06 0.607 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 0.976 0.934 – 1.02 0.271 2204 22031 all phecode
375.2 Epiphora Sense Organs 0.969 0.905 – 1.04 0.377 898 8969 all phecode
376 Disorders of the orbit Sense Organs 0.993 0.79 – 1.25 0.949 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.956 0.858 – 1.06 0.411 361 3618 all phecode
377.1 Optic atrophy Sense Organs 0.912 0.699 – 1.19 0.496 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.13 0.936 – 1.36 0.204 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.07 1.01 – 1.13 0.0183 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.06 0.99 – 1.13 0.0964 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.09 0.948 – 1.25 0.23 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 1.08 0.955 – 1.22 0.218 275 2755 all phecode
379 Other disorders of eye Sense Organs 0.982 0.95 – 1.02 0.301 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 0.964 0.912 – 1.02 0.192 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.99 0.943 – 1.04 0.693 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.15 0.905 – 1.46 0.255 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.945 0.852 – 1.05 0.286 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.1 0.943 – 1.29 0.222 169 1690 all phecode
380 Disorders of external ear Sense Organs 1.04 0.961 – 1.13 0.312 642 6413 all phecode
380.1 Otitis externa Sense Organs 1 0.915 – 1.1 0.939 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 1.05 0.946 – 1.17 0.344 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.985 0.942 – 1.03 0.504 2150 21493 all phecode
381.1 Otitis media Sense Organs 0.98 0.933 – 1.03 0.409 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.979 0.913 – 1.05 0.563 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 1.02 0.878 – 1.18 0.825 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.02 0.87 – 1.19 0.839 171 1709 all phecode
381.9 Otorrhea Sense Organs 0.941 0.832 – 1.06 0.331 281 2807 all phecode
382 Otalgia Sense Organs 0.957 0.85 – 1.08 0.468 308 3084 all phecode
383 Otosclerosis Sense Organs 1.02 0.907 – 1.15 0.743 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.05 0.99 – 1.11 0.106 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.05 0.987 – 1.12 0.122 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.01 0.941 – 1.09 0.74 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 0.968 0.891 – 1.05 0.444 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.04 0.915 – 1.19 0.521 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.01 0.958 – 1.06 0.813 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 1.04 0.959 – 1.14 0.319 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 0.951 0.856 – 1.06 0.354 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 1.01 0.936 – 1.09 0.837 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.01 0.978 – 1.04 0.585 4582 45806 all phecode
388 Other disorders of ear Sense Organs 1.18 1.02 – 1.36 0.0289 202 2017 all phecode
389 Hearing loss Sense Organs 0.972 0.942 – 1 0.0856 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.901 0.818 – 0.992 0.0345 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 1.02 0.927 – 1.12 0.681 450 4497 all phecode
389.4 Tinnitus Sense Organs 1.04 0.953 – 1.14 0.358 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 0.991 0.963 – 1.02 0.569 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 1.01 0.977 – 1.05 0.447 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 0.98 0.925 – 1.04 0.483 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 0.975 0.915 – 1.04 0.428 1058 10566 all phecode
395 Heart valve disorders Circulatory System 0.997 0.966 – 1.03 0.866 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.01 0.976 – 1.05 0.471 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.988 0.873 – 1.12 0.85 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.09 0.894 – 1.34 0.386 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.92 0.75 – 1.13 0.426 97 970 all phecode
395.6 Heart valve replaced Circulatory System 0.97 0.92 – 1.02 0.261 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 1.01 0.943 – 1.07 0.872 1048 10468 all phecode
401 Hypertension Circulatory System 1 0.996 – 1.01 0.326 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 1 0.996 – 1.01 0.346 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.01 0.959 – 1.05 0.824 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 1.1 0.992 – 1.23 0.0695 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.991 0.94 – 1.04 0.727 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 1.02 0.859 – 1.21 0.842 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.03 0.979 – 1.09 0.244 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 0.982 0.971 – 0.994 0.00375 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.966 0.939 – 0.994 0.0171 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 0.987 0.968 – 1.01 0.165 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 0.982 0.966 – 0.999 0.0345 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 0.981 0.967 – 0.996 0.0113 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.01 0.932 – 1.09 0.83 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.994 0.978 – 1.01 0.49 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.979 0.923 – 1.04 0.479 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 0.967 0.921 – 1.01 0.173 1823 18228 all phecode
414.2 ASCVD Circulatory System 1.04 0.817 – 1.31 0.773 72 719 all phecode
415 Pulmonary heart disease Circulatory System 1 0.972 – 1.03 0.903 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.28 1.02 – 1.61 0.0315 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.971 0.893 – 1.06 0.498 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 0.959 0.871 – 1.06 0.391 448 4475 all phecode
416 Cardiomegaly Circulatory System 0.993 0.954 – 1.03 0.731 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 1.01 0.998 – 1.02 0.115 28599 270106 all phecode
418.1 Precordial pain Circulatory System 0.977 0.944 – 1.01 0.194 3551 35541 all phecode
420 Carditis Circulatory System 0.999 0.955 – 1.04 0.948 2106 21053 all phecode
420.1 Myocarditis Circulatory System 0.987 0.82 – 1.19 0.89 127 1267 all phecode
420.2 Pericarditis Circulatory System 0.99 0.936 – 1.05 0.718 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 1.02 0.889 – 1.17 0.793 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 1.04 0.86 – 1.26 0.671 113 1129 all phecode
420.3 Endocarditis Circulatory System 1.03 0.955 – 1.11 0.43 719 7194 all phecode
425 Cardiomyopathy Circulatory System 0.996 0.94 – 1.06 0.901 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.993 0.936 – 1.05 0.823 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.04 0.869 – 1.24 0.687 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.954 0.814 – 1.12 0.559 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 1.13 0.87 – 1.48 0.354 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 1.02 0.992 – 1.04 0.185 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 0.989 0.946 – 1.03 0.618 2114 21162 all phecode
426.21 First degree AV block Circulatory System 1.01 0.945 – 1.08 0.768 986 9867 all phecode
426.23 Second degree AV block Circulatory System 1.03 0.94 – 1.14 0.489 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 0.916 0.843 – 0.996 0.0392 587 5868 all phecode
426.25 Other heart block Circulatory System 0.932 0.783 – 1.11 0.431 131 1318 all phecode
426.3 Bundle branch block Circulatory System 1.01 0.976 – 1.05 0.538 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 0.974 0.923 – 1.03 0.328 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 1.03 0.982 – 1.08 0.219 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.04 0.907 – 1.19 0.595 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 0.895 0.686 – 1.17 0.416 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.02 0.975 – 1.06 0.446 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.02 0.981 – 1.07 0.279 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 1.01 0.992 – 1.02 0.437 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.02 0.986 – 1.06 0.223 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.04 0.995 – 1.08 0.0873 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.01 0.942 – 1.08 0.816 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1 0.986 – 1.02 0.738 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.992 0.956 – 1.03 0.645 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.01 0.95 – 1.07 0.798 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.05 0.935 – 1.17 0.432 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 0.99 0.928 – 1.06 0.762 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.972 0.91 – 1.04 0.403 952 9541 all phecode
427.6 Premature beats Circulatory System 0.98 0.896 – 1.07 0.651 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 0.992 0.824 – 1.19 0.933 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 1.04 0.995 – 1.09 0.0792 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.03 0.935 – 1.15 0.51 402 4029 all phecode
427.9 Palpitations Circulatory System 1.01 0.979 – 1.05 0.474 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.97 0.944 – 0.997 0.0306 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 0.95 0.909 – 0.994 0.0268 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 0.976 0.946 – 1.01 0.119 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 0.935 0.865 – 1.01 0.0883 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 0.95 0.732 – 1.23 0.699 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.909 0.83 – 0.994 0.0373 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.03 0.891 – 1.2 0.659 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 1 0.958 – 1.05 0.846 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.961 0.895 – 1.03 0.278 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1.01 0.935 – 1.08 0.847 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 1.08 0.952 – 1.22 0.242 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 0.985 0.964 – 1.01 0.176 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.993 0.935 – 1.05 0.805 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 0.981 0.857 – 1.12 0.779 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.97 0.94 – 1 0.0623 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.943 0.897 – 0.992 0.0221 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 1.02 0.986 – 1.06 0.217 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.02 0.976 – 1.07 0.38 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 0.987 0.891 – 1.09 0.804 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.936 0.884 – 0.991 0.023 1279 12783 all phecode
440 Atherosclerosis Circulatory System 0.98 0.927 – 1.04 0.467 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.966 0.792 – 1.18 0.731 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.02 0.944 – 1.09 0.687 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 0.939 0.832 – 1.06 0.313 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 0.979 0.901 – 1.06 0.616 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.958 0.849 – 1.08 0.482 283 2827 all phecode
442 Other aneurysm Circulatory System 0.984 0.939 – 1.03 0.517 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 0.993 0.941 – 1.05 0.809 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.98 0.916 – 1.05 0.567 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 0.957 0.779 – 1.18 0.679 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.967 0.824 – 1.14 0.683 169 1696 all phecode
442.4 Arterial dissection Circulatory System 1.09 0.829 – 1.43 0.544 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 0.945 0.816 – 1.09 0.448 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 0.981 0.95 – 1.01 0.261 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 1.07 1.01 – 1.14 0.0204 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.961 0.865 – 1.07 0.46 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 0.983 0.95 – 1.02 0.308 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.955 0.917 – 0.995 0.026 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 0.946 0.883 – 1.01 0.108 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.928 0.85 – 1.01 0.0989 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.02 0.952 – 1.1 0.542 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 1.01 0.873 – 1.18 0.85 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 1.04 0.94 – 1.15 0.448 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 0.993 0.871 – 1.13 0.919 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 0.936 0.885 – 0.991 0.0221 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 0.914 0.853 – 0.98 0.0117 868 8712 all phecode
448 Disease of capillaries Circulatory System 1.07 0.901 – 1.27 0.447 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.04 0.964 – 1.13 0.303 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.02 0.983 – 1.05 0.346 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.01 0.979 – 1.05 0.473 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 0.915 0.839 – 0.997 0.0422 564 5645 all phecode
454 Varicose veins Circulatory System 0.992 0.973 – 1.01 0.416 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 0.988 0.969 – 1.01 0.227 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.981 0.903 – 1.07 0.647 624 6325 all phecode
455 Hemorrhoids Circulatory System 1.03 1.02 – 1.05 5.26e-06 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.969 0.832 – 1.13 0.685 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.996 0.819 – 1.21 0.969 97 967 all phecode
458 Hypotension Circulatory System 1.04 1.01 – 1.07 0.00426 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 1.07 1.01 – 1.13 0.019 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.19 1.04 – 1.36 0.0118 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 1.05 1.01 – 1.08 0.0116 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 1 0.985 – 1.02 0.921 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 0.924 0.775 – 1.1 0.376 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 1 0.984 – 1.02 0.977 16103 159422 all phecode
464 Acute sinusitis Respiratory 1.24 1.07 – 1.43 0.00444 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.988 0.947 – 1.03 0.597 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 0.996 0.927 – 1.07 0.908 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.871 0.745 – 1.02 0.0826 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.987 0.957 – 1.02 0.385 4654 46553 all phecode
471 Nasal polyps Respiratory 1.01 0.972 – 1.04 0.689 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.974 0.913 – 1.04 0.44 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 0.979 0.94 – 1.02 0.305 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 0.962 0.79 – 1.17 0.698 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.04 0.921 – 1.19 0.494 264 2647 all phecode
473.4 Voice disturbance Respiratory 1.01 0.947 – 1.07 0.817 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 1 0.954 – 1.05 0.96 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 0.988 0.904 – 1.08 0.784 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.04 0.974 – 1.1 0.262 1122 11199 all phecode
475 Chronic sinusitis Respiratory 1 0.965 – 1.05 0.816 2589 25882 all phecode
476 Allergic rhinitis Respiratory 1.02 0.957 – 1.09 0.56 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 0.965 0.926 – 1.01 0.0912 2447 24452 all phecode
478 Throat pain Respiratory 0.894 0.804 – 0.993 0.0365 377 3789 all phecode
479 Other upper respiratory disease Respiratory 0.995 0.964 – 1.03 0.771 4074 40737 all phecode
480 Pneumonia Respiratory 1.01 0.993 – 1.03 0.199 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 1.01 0.987 – 1.04 0.364 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.01 0.98 – 1.03 0.612 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.22 0.988 – 1.51 0.0646 93 929 all phecode
480.2 Viral pneumonia Respiratory 0.979 0.776 – 1.23 0.857 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.99 0.807 – 1.21 0.923 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.03 0.954 – 1.1 0.487 794 7951 all phecode
481 Influenza Respiratory 0.965 0.864 – 1.08 0.522 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.925 0.796 – 1.07 0.308 193 1930 all phecode
495 Asthma Respiratory 1.01 1 – 1.03 0.0263 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 1.08 0.944 – 1.23 0.265 250 2510 all phecode
496 Chronic airway obstruction Respiratory 1.02 0.997 – 1.04 0.0929 10424 101546 all phecode
496.1 Emphysema Respiratory 1.05 0.998 – 1.1 0.0593 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 1.05 1.01 – 1.09 0.0164 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.05 1.01 – 1.09 0.0121 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 1 0.956 – 1.05 0.924 1885 18859 all phecode
497 Bronchitis Respiratory 0.935 0.861 – 1.01 0.108 626 6267 all phecode
500 Lung disease due to external agents Respiratory 0.927 0.839 – 1.02 0.135 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.918 0.736 – 1.15 0.449 79 784 all phecode
500.2 Pneumoconiosis Respiratory 0.94 0.827 – 1.07 0.34 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.07 0.989 – 1.16 0.0933 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.999 0.933 – 1.07 0.975 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 0.931 0.849 – 1.02 0.124 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.89 0.795 – 0.997 0.0436 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 0.915 0.707 – 1.18 0.498 61 610 all phecode
506 Empyema and pneumothorax Respiratory 1.03 0.967 – 1.09 0.385 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 1.02 0.994 – 1.05 0.129 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.09 1.04 – 1.14 5e-04 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1 0.961 – 1.04 0.976 2599 26031 all phecode
509.1 Respiratory failure Respiratory 0.996 0.952 – 1.04 0.87 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 0.989 0.943 – 1.04 0.668 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 1.09 0.918 – 1.3 0.32 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.01 0.911 – 1.13 0.799 386 3863 all phecode
510 Other diseases of lung Respiratory 1.1 1.02 – 1.18 0.0131 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 0.993 0.971 – 1.01 0.497 9031 90349 all phecode
512.1 Wheezing Respiratory 1.05 0.915 – 1.21 0.483 220 2196 all phecode
512.2 Painful respiration Respiratory 1.05 0.91 – 1.2 0.523 207 2075 all phecode
512.7 Shortness of breath Respiratory 0.995 0.969 – 1.02 0.738 5842 58498 all phecode
512.8 Cough Respiratory 0.979 0.942 – 1.02 0.28 2866 28642 all phecode
512.9 Other dyspnea Respiratory 0.998 0.932 – 1.07 0.946 914 9124 all phecode
513 Respiratory abnormalities Respiratory 0.966 0.888 – 1.05 0.414 611 6112 all phecode
513.3 Hypoventilation Respiratory 1.01 0.812 – 1.26 0.916 83 830 all phecode
513.4 Hyperventilation Respiratory 0.983 0.868 – 1.11 0.782 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 0.912 0.771 – 1.08 0.281 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 0.998 0.958 – 1.04 0.937 2465 24673 all phecode
516 Abnormal sputum Respiratory 1.01 0.967 – 1.06 0.639 2132 21335 all phecode
516.1 Hemoptysis Respiratory 1 0.958 – 1.05 0.907 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.02 1 – 1.04 0.0389 9366 93681 all phecode
519.2 Respiratory complications Respiratory 0.995 0.889 – 1.11 0.931 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.02 1 – 1.04 0.0546 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.98 0.874 – 1.1 0.726 303 3049 all phecode
520 Disorders of tooth development Digestive 1.01 0.966 – 1.06 0.628 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.1 0.813 – 1.47 0.549 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 1.01 0.972 – 1.06 0.51 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 1.01 0.97 – 1.05 0.719 3016 30245 all phecode
521.1 Dental caries Digestive 1.01 0.974 – 1.05 0.557 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.03 0.979 – 1.08 0.27 1774 17750 all phecode
522.5 Periapical abscess Digestive 1.02 0.963 – 1.09 0.472 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 1.01 0.956 – 1.06 0.836 1681 16812 all phecode
523.1 Gingivitis Digestive 0.974 0.801 – 1.19 0.796 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 0.962 0.906 – 1.02 0.202 1165 11650 all phecode
523.31 Acute periodontitis Digestive 0.938 0.866 – 1.01 0.11 666 6667 all phecode
523.32 Chronic periodontitis Digestive 0.999 0.915 – 1.09 0.982 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.01 0.899 – 1.13 0.888 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.02 0.907 – 1.15 0.734 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.05 1 – 1.09 0.0288 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.19 0.95 – 1.5 0.13 72 720 all phecode
526 Diseases of the jaws Digestive 0.999 0.934 – 1.07 0.975 928 9279 all phecode
526.1 Cysts of the jaws Digestive 0.971 0.866 – 1.09 0.617 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.07 0.823 – 1.4 0.602 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 0.871 0.762 – 0.996 0.0436 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.862 0.752 – 0.987 0.032 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 1.08 0.891 – 1.3 0.445 110 1098 all phecode
526.9 Jaw disease NOS Digestive 1.04 0.914 – 1.19 0.537 233 2329 all phecode
527 Diseases of the salivary glands Digestive 0.973 0.9 – 1.05 0.495 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.04 0.834 – 1.29 0.734 84 838 all phecode
527.2 Sialoadenitis Digestive 0.934 0.84 – 1.04 0.214 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 1.08 0.835 – 1.4 0.556 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.05 0.873 – 1.27 0.583 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1 0.969 – 1.04 0.903 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 1.07 0.976 – 1.18 0.144 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.11 0.994 – 1.23 0.0636 389 3884 all phecode
528.12 Oral aphthae Digestive 0.943 0.752 – 1.18 0.615 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.03 0.886 – 1.19 0.712 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 0.912 0.755 – 1.1 0.344 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 0.857 0.69 – 1.06 0.161 94 940 all phecode
528.5 Diseases of lips Digestive 1.01 0.935 – 1.1 0.767 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 0.928 0.825 – 1.04 0.207 308 3079 all phecode
528.7 Sialolithiasis Digestive 0.971 0.865 – 1.09 0.624 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 1.01 0.949 – 1.07 0.828 1232 12312 all phecode
529.1 Glossitis Digestive 0.976 0.869 – 1.1 0.689 299 2986 all phecode
530 Diseases of esophagus Digestive 1.01 0.997 – 1.02 0.168 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.01 0.998 – 1.02 0.11 31253 272429 all phecode
530.11 GERD Digestive 1 0.99 – 1.02 0.559 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 1.01 0.981 – 1.04 0.538 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 0.989 0.969 – 1.01 0.283 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1 0.952 – 1.05 0.971 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 0.978 0.933 – 1.03 0.365 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 1.03 0.949 – 1.12 0.481 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.12 0.95 – 1.33 0.173 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.971 0.869 – 1.09 0.608 341 3416 all phecode
530.9 Heartburn Digestive 0.994 0.951 – 1.04 0.798 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.997 0.973 – 1.02 0.839 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.99 0.912 – 1.07 0.802 637 6374 all phecode
531.2 Gastric ulcer Digestive 0.978 0.947 – 1.01 0.171 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 1.01 0.977 – 1.05 0.463 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 0.945 0.857 – 1.04 0.26 427 4268 all phecode
532 Dysphagia Digestive 0.996 0.971 – 1.02 0.78 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 1.01 0.998 – 1.02 0.106 28078 261548 all phecode
535.1 Acute gastritis Digestive 0.96 0.903 – 1.02 0.183 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 0.944 0.849 – 1.05 0.294 370 3687 all phecode
535.6 Duodenitis Digestive 1.01 0.99 – 1.04 0.265 7592 75928 all phecode
535.8 Other specified gastritis Digestive 1 0.977 – 1.02 0.987 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.09 0.904 – 1.31 0.373 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.04 0.915 – 1.18 0.566 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 1.02 0.988 – 1.06 0.19 3391 33907 all phecode
540 Appendiceal conditions Digestive 1.01 0.972 – 1.05 0.667 3088 30890 all phecode
540.1 Appendicitis Digestive 1 0.964 – 1.04 0.959 2895 28963 all phecode
540.11 Acute appendicitis Digestive 0.997 0.958 – 1.04 0.897 2601 26019 all phecode
550 Abdominal hernia Digestive 1.01 0.999 – 1.02 0.0672 45429 282640 all phecode
550.1 Inguinal hernia Digestive 1.01 0.995 – 1.03 0.187 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 1.01 0.993 – 1.02 0.343 26494 238953 all phecode
550.3 Femoral hernia Digestive 0.997 0.919 – 1.08 0.941 651 6504 all phecode
550.4 Umbilical hernia Digestive 0.982 0.949 – 1.02 0.29 3705 37072 all phecode
550.5 Ventral hernia Digestive 1.05 1.01 – 1.09 0.00622 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.01 0.98 – 1.04 0.496 4444 44442 all phecode
555.1 Regional enteritis Digestive 0.999 0.951 – 1.05 0.966 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 1.03 0.989 – 1.06 0.169 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.04 0.952 – 1.13 0.395 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 1.01 0.945 – 1.07 0.832 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 1.03 0.953 – 1.12 0.436 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.04 0.921 – 1.17 0.535 299 2987 all phecode
557.1 Celiac disease Digestive 1.03 0.982 – 1.08 0.217 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 1.01 0.993 – 1.03 0.25 15492 155105 all phecode
559 Ileostomy status Digestive 1.22 1.16 – 1.28 1.24e-14 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.06 1.03 – 1.1 0.000251 3936 39337 all phecode
560.1 Paralytic ileus Digestive 1.07 0.979 – 1.17 0.135 523 5231 all phecode
560.2 Impaction of intestine Digestive 1.02 0.898 – 1.15 0.789 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.09 1.02 – 1.17 0.0127 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 1.07 1.03 – 1.11 0.000196 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 0.986 0.97 – 1 0.103 15772 157686 all phecode
561.1 Diarrhea Digestive 1.01 0.92 – 1.11 0.801 466 4653 all phecode
561.2 Flatulence Digestive 0.993 0.944 – 1.04 0.78 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 1.07 1.05 – 1.08 2.12e-22 26714 211692 all phecode
562.1 Diverticulosis Digestive 1.07 1.05 – 1.08 1.76e-22 26672 211642 all phecode
563 Constipation Digestive 1.01 0.985 – 1.03 0.596 10314 103140 all phecode
564 Functional digestive disorders Digestive 1.08 1.06 – 1.09 1.44e-25 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.02 0.997 – 1.05 0.0847 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.11 1.05 – 1.17 8.19e-05 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 1.1 1.08 – 1.11 5.13e-27 15186 151648 all phecode
565 Anal and rectal conditions Digestive 1.13 1.11 – 1.15 3.49e-43 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 1.24 1.21 – 1.27 2.3e-67 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1.01 0.944 – 1.08 0.769 929 9293 all phecode
568 Other disorders of peritoneum Digestive 1.07 1.03 – 1.11 0.000407 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.07 1.03 – 1.11 0.000626 3101 30987 all phecode
569 Other disorders of intestine Digestive 1.11 1.08 – 1.15 8.17e-11 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.16 0.981 – 1.37 0.0825 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 1.28 1.17 – 1.41 1.78e-07 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.02 0.981 – 1.06 0.343 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1 0.954 – 1.05 0.918 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.947 0.778 – 1.15 0.586 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 1.04 0.914 – 1.18 0.575 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.04 0.976 – 1.11 0.213 976 9804 all phecode
571.81 Portal hypertension Digestive 1.08 0.988 – 1.18 0.0896 528 5285 all phecode
572 Ascites (non malignant) Digestive 1.01 0.961 – 1.07 0.653 1544 15454 all phecode
573 Other disorders of liver Digestive 1.06 1 – 1.12 0.0346 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 0.943 0.762 – 1.17 0.594 96 960 all phecode
573.3 Hepatomegaly Digestive 1.1 0.976 – 1.24 0.118 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 1.01 0.945 – 1.09 0.717 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 0.995 0.961 – 1.03 0.796 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 0.949 0.822 – 1.1 0.473 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.01 0.994 – 1.03 0.204 15607 156123 all phecode
574.1 Cholelithiasis Digestive 1.01 0.991 – 1.03 0.333 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.991 0.94 – 1.05 0.739 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.999 0.972 – 1.03 0.964 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 1.02 0.983 – 1.07 0.27 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.997 0.959 – 1.04 0.887 2748 27523 all phecode
575 Other biliary tract disease Digestive 1.04 1.01 – 1.07 0.0209 3867 38724 all phecode
575.1 Cholangitis Digestive 1 0.915 – 1.1 0.943 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 1.04 0.967 – 1.12 0.282 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 1.08 0.985 – 1.19 0.099 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 1 0.949 – 1.06 0.936 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 1.06 0.995 – 1.13 0.0716 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.12 1 – 1.24 0.0456 348 3488 all phecode
577 Diseases of pancreas Digestive 0.976 0.938 – 1.02 0.23 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 0.971 0.927 – 1.02 0.202 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 1.02 0.929 – 1.11 0.727 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.02 0.92 – 1.14 0.68 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 1.02 1.01 – 1.04 0.00245 20626 206278 all phecode
578.1 Hematemesis Digestive 1.03 0.982 – 1.08 0.234 1958 19564 all phecode
578.2 Blood in stool Digestive 1.01 0.967 – 1.05 0.745 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.03 1.01 – 1.04 0.00684 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.03 0.996 – 1.05 0.0863 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.04 0.984 – 1.09 0.176 1548 15498 all phecode
579.2 Splenomegaly Digestive 0.997 0.903 – 1.1 0.95 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.03 0.983 – 1.09 0.194 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.03 0.98 – 1.09 0.235 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 1.03 0.967 – 1.1 0.348 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.12 0.872 – 1.44 0.376 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.21 1.01 – 1.45 0.0341 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1 0.936 – 1.08 0.914 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.99 0.9 – 1.09 0.843 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.16 1.02 – 1.33 0.0236 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.16 1.02 – 1.32 0.0234 253 2529 all phecode
585 Renal failure Genitourinary 1.01 0.986 – 1.04 0.398 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 1.02 0.988 – 1.05 0.24 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 0.972 0.922 – 1.03 0.304 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.03 0.993 – 1.08 0.111 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 1.08 0.982 – 1.18 0.116 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.03 0.992 – 1.07 0.123 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.08 0.941 – 1.25 0.265 208 2089 all phecode
586.11 Small kidney Genitourinary 1.14 0.978 – 1.32 0.094 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.07 1.01 – 1.14 0.0207 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.14 0.899 – 1.43 0.287 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.981 0.915 – 1.05 0.576 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 1.08 0.974 – 1.21 0.139 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.22 0.988 – 1.52 0.0638 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.07 0.883 – 1.3 0.485 116 1158 all phecode
590 Pyelonephritis Genitourinary 1.03 0.975 – 1.09 0.275 1328 13285 all phecode
591 Urinary tract infection Genitourinary 1.03 1.01 – 1.05 0.00529 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 0.991 0.954 – 1.03 0.644 2966 29661 all phecode
592.1 Cystitis Genitourinary 1 0.965 – 1.04 0.898 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 0.94 0.79 – 1.12 0.484 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 0.959 0.895 – 1.03 0.241 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.986 0.865 – 1.12 0.833 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.871 0.741 – 1.02 0.0919 165 1662 all phecode
593 Hematuria Genitourinary 1.01 0.991 – 1.02 0.369 16068 160204 all phecode
594 Urinary calculus Genitourinary 1.01 0.983 – 1.03 0.529 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 0.976 0.941 – 1.01 0.196 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.02 0.945 – 1.1 0.64 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 1.03 0.984 – 1.07 0.227 2401 24024 all phecode
594.8 Renal colic Genitourinary 1.05 0.999 – 1.09 0.0559 2050 20500 all phecode
595 Hydronephrosis Genitourinary 1.02 0.975 – 1.07 0.376 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 1 0.983 – 1.03 0.706 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 0.988 0.943 – 1.04 0.616 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 1.03 0.975 – 1.08 0.33 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.986 0.954 – 1.02 0.403 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.978 0.944 – 1.01 0.228 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 0.914 0.723 – 1.16 0.453 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 0.994 0.96 – 1.03 0.724 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.912 0.811 – 1.03 0.127 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.992 – 1.02 0.343 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 1.12 0.952 – 1.31 0.175 166 1670 all phecode
599.2 Retention of urine Genitourinary 1.01 0.981 – 1.03 0.628 6718 67168 all phecode
599.3 Dysuria Genitourinary 0.983 0.926 – 1.04 0.577 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 1.01 0.988 – 1.03 0.384 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1.01 0.979 – 1.04 0.5 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 1.1 0.905 – 1.33 0.341 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 0.903 0.695 – 1.17 0.442 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 1.03 0.986 – 1.08 0.172 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 1 0.984 – 1.02 0.691 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 1.01 0.962 – 1.05 0.777 2081 20818 all phecode
601.1 Prostatitis Genitourinary 1.01 0.955 – 1.06 0.845 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 0.995 0.871 – 1.14 0.945 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 0.968 0.905 – 1.04 0.34 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 1.03 0.794 – 1.34 0.827 59 588 all phecode
601.4 Balanoposthitis Genitourinary 0.969 0.86 – 1.09 0.605 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.02 0.91 – 1.15 0.688 303 3019 all phecode
602 Other disorders of prostate Genitourinary 0.952 0.9 – 1.01 0.082 1341 13408 all phecode
603 Other disorders of testis Genitourinary 1.01 0.962 – 1.05 0.801 2150 21512 all phecode
603.1 Hydrocele Genitourinary 1.02 0.965 – 1.08 0.458 1339 13402 all phecode
604 Disorders of penis Genitourinary 0.975 0.941 – 1.01 0.169 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.983 0.945 – 1.02 0.386 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 1.01 0.891 – 1.14 0.914 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 1.02 0.981 – 1.06 0.318 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.05 0.92 – 1.21 0.45 214 2138 all phecode
609.1 Infertility, male Genitourinary 0.891 0.693 – 1.15 0.371 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 1.09 0.937 – 1.27 0.26 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 1.03 0.99 – 1.08 0.137 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 1.02 0.952 – 1.09 0.596 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.2 1.07 – 1.35 0.00242 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 1.02 0.906 – 1.15 0.745 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 1.03 0.973 – 1.09 0.326 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1 0.928 – 1.08 0.948 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.04 0.992 – 1.1 0.0974 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 0.952 0.73 – 1.24 0.714 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 1.05 0.992 – 1.1 0.098 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.05 0.978 – 1.12 0.185 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.04 0.969 – 1.12 0.274 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 1.04 0.827 – 1.32 0.717 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 1.09 1.04 – 1.15 0.000811 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 1.09 1.01 – 1.18 0.024 720 7210 all phecode
613.5 Mastodynia Genitourinary 1.1 0.882 – 1.37 0.396 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 1.04 0.965 – 1.13 0.289 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 1.04 0.93 – 1.17 0.478 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 1.05 0.91 – 1.21 0.506 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.998 0.972 – 1.03 0.913 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1 0.965 – 1.05 0.818 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.01 0.936 – 1.08 0.877 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.904 0.697 – 1.17 0.449 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.951 0.86 – 1.05 0.333 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.06 0.95 – 1.19 0.283 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.935 0.826 – 1.06 0.285 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.978 0.94 – 1.02 0.29 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.991 0.936 – 1.05 0.749 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.948 0.859 – 1.05 0.286 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.03 0.955 – 1.11 0.444 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.929 0.822 – 1.05 0.235 274 2737 all phecode
615 Endometriosis Genitourinary 1.02 0.984 – 1.05 0.323 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.04 0.922 – 1.17 0.529 304 3037 all phecode
618 Genital prolapse Genitourinary 1.01 0.987 – 1.03 0.555 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1.02 0.992 – 1.04 0.207 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.999 0.971 – 1.03 0.924 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.973 0.889 – 1.06 0.544 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.994 0.919 – 1.07 0.877 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.998 0.976 – 1.02 0.857 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.895 0.83 – 0.966 0.00414 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 0.997 0.962 – 1.03 0.873 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.02 0.983 – 1.06 0.279 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.989 0.941 – 1.04 0.646 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.03 0.971 – 1.09 0.346 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 1.11 0.878 – 1.42 0.373 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 0.944 0.888 – 1 0.0602 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 1.01 0.988 – 1.03 0.425 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 1 0.981 – 1.03 0.724 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 1 0.97 – 1.04 0.808 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.04 0.986 – 1.11 0.142 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 0.975 0.907 – 1.05 0.497 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.968 0.849 – 1.11 0.634 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.974 0.884 – 1.07 0.596 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 1.01 0.983 – 1.04 0.474 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.998 0.96 – 1.04 0.916 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 1.03 0.97 – 1.09 0.334 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.01 0.989 – 1.02 0.537 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.01 0.988 – 1.02 0.53 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 0.989 0.815 – 1.2 0.912 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1 0.981 – 1.02 0.878 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 1.02 0.972 – 1.07 0.464 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 1 0.969 – 1.04 0.908 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 0.992 0.945 – 1.04 0.737 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.944 0.803 – 1.11 0.482 159 1587 all phecode
626.8 Infertility, female Genitourinary 0.971 0.918 – 1.03 0.297 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 1 0.984 – 1.02 0.706 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 1.01 0.985 – 1.03 0.571 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 0.966 0.831 – 1.12 0.659 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.02 0.961 – 1.09 0.482 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.922 0.82 – 1.04 0.177 310 3097 all phecode
628 Ovarian cyst Genitourinary 0.998 0.969 – 1.03 0.904 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.982 0.954 – 1.01 0.229 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.967 0.909 – 1.03 0.275 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.85 0.759 – 0.952 0.00495 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.977 0.933 – 1.02 0.334 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.955 0.89 – 1.02 0.196 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.01 0.955 – 1.07 0.69 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.976 0.935 – 1.02 0.266 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.979 0.903 – 1.06 0.613 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.954 0.896 – 1.02 0.141 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 0.98 0.771 – 1.25 0.868 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.997 0.937 – 1.06 0.927 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.982 0.872 – 1.1 0.759 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.08 0.937 – 1.24 0.292 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.09 0.924 – 1.29 0.302 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.988 0.932 – 1.05 0.681 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1 0.962 – 1.05 0.837 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.16 0.902 – 1.48 0.253 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.925 0.818 – 1.05 0.215 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.95 0.785 – 1.15 0.603 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.978 0.845 – 1.13 0.769 193 1922 all phecode
650 Normal delivery Pregnancy Complications 1.06 1.01 – 1.11 0.0203 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 0.965 0.863 – 1.08 0.536 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.986 0.939 – 1.04 0.589 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.98 0.927 – 1.04 0.464 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.03 0.816 – 1.31 0.782 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.01 0.975 – 1.04 0.68 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.01 0.825 – 1.23 0.936 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 1.01 0.967 – 1.06 0.638 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 1.06 0.971 – 1.16 0.188 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 1.02 0.993 – 1.05 0.131 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.04 0.998 – 1.08 0.0653 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.21 1.04 – 1.42 0.0165 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.93 0.822 – 1.05 0.254 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.03 0.808 – 1.32 0.789 63 624 all phecode
679 Complications of in utero procedures Dermatologic 0.946 0.713 – 1.26 0.701 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.01 0.989 – 1.04 0.303 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.955 0.876 – 1.04 0.297 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.983 0.9 – 1.07 0.709 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.02 0.99 – 1.05 0.204 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.02 0.99 – 1.05 0.211 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.02 0.99 – 1.05 0.207 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.04 0.954 – 1.13 0.393 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.01 0.955 – 1.07 0.73 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.03 0.987 – 1.08 0.172 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 1.07 0.983 – 1.16 0.12 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 1.03 0.929 – 1.15 0.537 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 1.03 0.943 – 1.12 0.53 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.993 0.95 – 1.04 0.765 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 0.995 0.881 – 1.12 0.93 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 1.29 1.06 – 1.56 0.0107 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.01 0.973 – 1.05 0.593 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.01 0.984 – 1.04 0.439 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.983 0.761 – 1.27 0.895 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.858 0.636 – 1.16 0.313 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 1.16 0.972 – 1.4 0.0988 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 1.04 0.972 – 1.11 0.269 986 9854 all phecode
694.1 Vitiligo Dermatologic 1.6 1.22 – 2.09 0.000616 60 599 all phecode
694.2 Other dyschromia Dermatologic 1.02 0.946 – 1.09 0.653 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 0.911 0.754 – 1.1 0.33 117 1170 all phecode
695 Erythematous conditions Dermatologic 1.03 0.989 – 1.08 0.15 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 0.933 0.769 – 1.13 0.481 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 1.11 0.925 – 1.32 0.269 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 1.08 0.819 – 1.43 0.583 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.08 0.848 – 1.36 0.549 73 727 all phecode
695.3 Rosacea Dermatologic 1.01 0.895 – 1.13 0.92 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.07 0.971 – 1.19 0.169 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.06 0.88 – 1.27 0.546 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.06 0.952 – 1.19 0.28 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 1.07 0.991 – 1.15 0.0851 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 0.926 0.809 – 1.06 0.262 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 0.964 0.771 – 1.21 0.752 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.06 0.965 – 1.17 0.221 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 1.02 0.972 – 1.06 0.492 2252 22509 all phecode
696.4 Psoriasis Dermatologic 1.02 0.972 – 1.06 0.494 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 1 0.954 – 1.05 0.912 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.04 0.96 – 1.12 0.358 706 7052 all phecode
697 Sarcoidosis Dermatologic 1.05 0.966 – 1.15 0.237 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 0.98 0.91 – 1.06 0.589 782 7814 all phecode
700 Corns and callosities Dermatologic 1.07 0.948 – 1.21 0.278 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.02 0.986 – 1.05 0.288 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 0.953 0.763 – 1.19 0.671 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1 0.962 – 1.05 0.876 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.17 0.898 – 1.52 0.247 61 610 all phecode
701.4 Keloid scar Dermatologic 1.11 0.971 – 1.27 0.126 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 1.06 0.966 – 1.17 0.213 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.1 0.9 – 1.34 0.357 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.02 0.991 – 1.05 0.187 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 1.01 0.974 – 1.06 0.502 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 1.01 0.978 – 1.05 0.433 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 1.04 0.933 – 1.16 0.472 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 0.927 0.868 – 0.99 0.0233 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 1.03 0.999 – 1.06 0.0559 5267 52727 all phecode
704.1 Alopecia Dermatologic 1.14 0.948 – 1.36 0.169 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.914 0.717 – 1.16 0.465 76 759 all phecode
705 Disorders of sweat glands Dermatologic 1.16 1.02 – 1.33 0.0286 228 2287 all phecode
705.3 Hidradenitis Dermatologic 1.17 1.01 – 1.36 0.0392 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 1.01 0.93 – 1.1 0.785 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 1.03 1.01 – 1.05 0.0072 8317 83195 all phecode
706.1 Acne Dermatologic 1.16 0.922 – 1.46 0.207 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 1.03 1.01 – 1.05 0.0107 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 1.01 0.96 – 1.05 0.816 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 1.03 0.962 – 1.1 0.403 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 1.02 0.986 – 1.06 0.238 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 0.955 0.871 – 1.05 0.324 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 1.3 1.11 – 1.51 0.000925 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.21 0.936 – 1.57 0.145 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.03 0.985 – 1.07 0.218 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.06 0.974 – 1.15 0.178 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 1.07 0.984 – 1.17 0.11 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.06 0.914 – 1.23 0.446 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.07 0.962 – 1.18 0.221 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 0.979 0.886 – 1.08 0.674 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 0.959 0.857 – 1.07 0.46 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.21 0.973 – 1.5 0.0868 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.05 0.892 – 1.23 0.584 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.08 0.853 – 1.37 0.514 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.02 0.987 – 1.05 0.287 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.02 0.987 – 1.05 0.244 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.05 1 – 1.11 0.0467 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.07 0.889 – 1.29 0.468 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.08 0.998 – 1.17 0.0567 618 6177 all phecode
716 Other arthropathies Musculoskeletal 1.01 1 – 1.03 0.00974 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1 0.967 – 1.04 0.962 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.02 1.01 – 1.04 0.00558 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.01 1 – 1.03 0.013 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.995 0.937 – 1.06 0.881 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 0.981 0.948 – 1.01 0.254 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1 0.981 – 1.03 0.73 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.983 0.955 – 1.01 0.247 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.03 0.889 – 1.2 0.676 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.19 1.06 – 1.33 0.00216 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 0.999 0.977 – 1.02 0.915 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.981 0.896 – 1.07 0.675 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1 0.965 – 1.04 0.854 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.15 0.888 – 1.49 0.29 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.996 0.966 – 1.03 0.822 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 0.993 0.908 – 1.09 0.887 517 5173 all phecode
723.1 Torticollis Musculoskeletal 1.09 0.895 – 1.33 0.387 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.01 0.961 – 1.05 0.81 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.07 0.967 – 1.19 0.189 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 1.08 0.976 – 1.2 0.132 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.02 0.786 – 1.33 0.877 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 0.988 0.939 – 1.04 0.642 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1 0.987 – 1.02 0.661 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 1 0.981 – 1.02 0.889 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 1.02 0.917 – 1.14 0.667 334 3336 all phecode
726.3 Bursitis Musculoskeletal 0.935 0.872 – 1 0.0599 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.01 0.982 – 1.03 0.628 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.01 0.967 – 1.05 0.77 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 0.903 0.741 – 1.1 0.313 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.02 0.988 – 1.06 0.191 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 0.985 0.904 – 1.07 0.733 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.983 0.882 – 1.1 0.764 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.991 0.836 – 1.17 0.917 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.978 0.946 – 1.01 0.2 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.08 0.972 – 1.19 0.157 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 0.987 0.955 – 1.02 0.437 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.984 0.951 – 1.02 0.374 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.01 0.983 – 1.04 0.479 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.955 0.895 – 1.02 0.165 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 0.921 0.751 – 1.13 0.428 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.991 0.877 – 1.12 0.885 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.985 0.868 – 1.12 0.812 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 0.989 0.901 – 1.09 0.826 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.89 0.771 – 1.03 0.111 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.939 0.72 – 1.23 0.645 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.02 0.971 – 1.07 0.451 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 1.05 0.932 – 1.18 0.438 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.963 0.882 – 1.05 0.402 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 0.956 0.803 – 1.14 0.609 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.963 0.907 – 1.02 0.207 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 0.921 0.765 – 1.11 0.38 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 1 0.983 – 1.02 0.744 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 0.942 0.81 – 1.1 0.444 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 1.01 0.983 – 1.04 0.444 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.992 0.946 – 1.04 0.731 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 1 0.949 – 1.05 0.984 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.01 0.988 – 1.04 0.298 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 1.01 0.957 – 1.06 0.79 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1.1 0.962 – 1.25 0.168 248 2476 all phecode
737 Curvature of spine Musculoskeletal 1.07 1 – 1.14 0.0371 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.07 1 – 1.14 0.0375 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.03 0.984 – 1.08 0.205 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1 0.953 – 1.06 0.867 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 1.09 0.991 – 1.19 0.0755 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 1.01 0.999 – 1.02 0.0671 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.02 1 – 1.03 0.0249 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.02 0.995 – 1.04 0.133 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.921 0.825 – 1.03 0.146 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.976 0.896 – 1.06 0.568 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1 0.982 – 1.02 0.977 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.02 0.981 – 1.05 0.375 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 1.15 0.934 – 1.41 0.192 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 1.01 0.928 – 1.09 0.871 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 0.914 0.775 – 1.08 0.284 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 1.01 0.958 – 1.07 0.696 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 1.06 0.881 – 1.28 0.53 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 0.979 0.744 – 1.29 0.877 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1 0.963 – 1.04 0.957 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 0.923 0.824 – 1.03 0.164 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.962 0.785 – 1.18 0.711 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.07 0.975 – 1.17 0.155 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 0.995 0.95 – 1.04 0.835 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.02 1 – 1.05 0.0536 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 1.03 1 – 1.05 0.0452 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 1.02 0.989 – 1.04 0.253 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 1.15 1.05 – 1.26 0.00185 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 1.03 0.941 – 1.12 0.533 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.953 0.887 – 1.02 0.189 815 8144 all phecode
745 Pain in joint Musculoskeletal 0.965 0.943 – 0.988 0.00251 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.987 0.949 – 1.03 0.506 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.984 0.945 – 1.02 0.423 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.958 0.881 – 1.04 0.322 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.999 0.875 – 1.14 0.986 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.01 0.961 – 1.06 0.708 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.04 0.886 – 1.22 0.633 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.22 0.92 – 1.63 0.165 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.973 0.865 – 1.09 0.643 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 1.08 1 – 1.17 0.0414 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.08 0.968 – 1.22 0.16 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.18 1.02 – 1.37 0.0289 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.1 0.991 – 1.23 0.0728 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.09 0.951 – 1.25 0.217 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.2 0.989 – 1.45 0.0641 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.987 0.937 – 1.04 0.622 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.972 0.9 – 1.05 0.471 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.04 0.943 – 1.14 0.455 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.856 0.745 – 0.984 0.0285 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.02 0.947 – 1.09 0.652 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 1.09 0.986 – 1.2 0.0922 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.893 0.799 – 0.998 0.0462 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.978 0.873 – 1.1 0.7 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 0.952 0.837 – 1.08 0.453 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 0.966 0.839 – 1.11 0.633 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1 0.799 – 1.26 0.99 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.12 0.932 – 1.34 0.233 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.01 0.798 – 1.27 0.962 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.972 0.798 – 1.18 0.773 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.02 0.924 – 1.13 0.681 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.932 0.81 – 1.07 0.33 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.993 0.847 – 1.17 0.935 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.996 0.817 – 1.21 0.968 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.02 0.935 – 1.11 0.696 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.11 0.885 – 1.38 0.378 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.03 0.938 – 1.14 0.498 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.945 0.799 – 1.12 0.51 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.797 0.615 – 1.03 0.086 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.796 0.69 – 0.917 0.00159 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.907 0.74 – 1.11 0.342 96 959 all phecode
760 Back pain Symptoms 0.991 0.972 – 1.01 0.369 11126 111353 all phecode
761 Cervicalgia Symptoms 0.975 0.928 – 1.02 0.298 1791 17901 all phecode
764 Sciatica Symptoms 0.929 0.89 – 0.969 0.000632 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.02 0.961 – 1.09 0.496 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 1.02 0.941 – 1.11 0.614 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.03 0.959 – 1.1 0.443 870 8687 all phecode
771.1 Swelling of limb Symptoms 1.02 0.99 – 1.05 0.189 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 0.99 0.914 – 1.07 0.8 659 6581 all phecode
773 Pain in limb Symptoms 1.01 0.985 – 1.04 0.425 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 0.947 0.811 – 1.11 0.497 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.991 0.945 – 1.04 0.721 1870 18715 all phecode
782.3 Edema Symptoms 0.991 0.942 – 1.04 0.73 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 1.15 0.988 – 1.34 0.0713 175 1748 all phecode
783 Fever of unknown origin Symptoms 0.981 0.949 – 1.01 0.258 3911 39105 all phecode
785 Abdominal pain Symptoms 1 0.994 – 1.02 0.365 40080 301686 all phecode
788 Syncope and collapse Symptoms 0.991 0.97 – 1.01 0.428 9069 90813 all phecode
789 Nausea and vomiting Symptoms 1.02 1 – 1.04 0.0492 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.16 0.978 – 1.37 0.0882 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 0.911 0.731 – 1.14 0.408 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.01 0.989 – 1.04 0.27 6357 63635 all phecode
791 Gangrene Symptoms 1.02 0.931 – 1.11 0.72 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.949 0.769 – 1.17 0.625 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.06 0.891 – 1.26 0.505 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.03 0.948 – 1.13 0.464 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.947 0.789 – 1.14 0.555 120 1198 all phecode
797 Shock Symptoms 1.11 0.94 – 1.3 0.226 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 1.07 0.88 – 1.31 0.491 102 1020 all phecode
798 Malaise and fatigue Symptoms 1 0.97 – 1.04 0.797 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 0.939 0.864 – 1.02 0.141 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 1 0.978 – 1.03 0.827 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.978 0.932 – 1.03 0.356 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.965 0.824 – 1.13 0.657 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.02 0.975 – 1.07 0.412 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 0.978 0.908 – 1.05 0.547 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.998 0.956 – 1.04 0.941 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.01 0.96 – 1.06 0.781 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.987 0.915 – 1.07 0.736 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.998 0.975 – 1.02 0.84 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 0.995 0.946 – 1.05 0.84 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.02 0.989 – 1.05 0.232 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.94 0.892 – 0.991 0.0215 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.998 0.963 – 1.03 0.891 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.964 0.912 – 1.02 0.199 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 1.01 0.932 – 1.08 0.895 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.951 0.898 – 1.01 0.0848 1300 12998 all phecode
817 Concussion Injuries & Poisonings 1.05 0.918 – 1.2 0.478 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.01 0.927 – 1.11 0.769 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.01 0.968 – 1.04 0.792 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 1.02 0.97 – 1.07 0.446 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 1.04 0.992 – 1.09 0.104 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 1.02 1 – 1.04 0.0368 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1 0.918 – 1.1 0.943 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 0.997 0.908 – 1.1 0.954 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.03 0.998 – 1.06 0.0727 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.03 0.88 – 1.21 0.695 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.1 1 – 1.2 0.0485 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.02 0.97 – 1.07 0.478 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.998 0.941 – 1.06 0.933 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.98 0.945 – 1.02 0.279 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.02 0.986 – 1.06 0.238 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 0.882 0.698 – 1.12 0.294 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.01 0.973 – 1.04 0.693 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.957 0.846 – 1.08 0.488 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 1 0.866 – 1.16 0.991 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 1 0.967 – 1.04 0.83 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.07 0.931 – 1.22 0.35 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 1 0.776 – 1.29 0.992 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.03 0.993 – 1.06 0.129 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.889 0.668 – 1.18 0.418 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.996 0.804 – 1.23 0.971 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.996 0.859 – 1.15 0.956 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 1.05 0.957 – 1.15 0.302 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 0.997 0.87 – 1.14 0.961 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.01 0.858 – 1.18 0.946 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 0.991 0.839 – 1.17 0.917 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 0.993 0.939 – 1.05 0.813 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 0.992 0.961 – 1.02 0.611 4260 42663 all phecode
916 Contusion Injuries & Poisonings 1.01 0.955 – 1.07 0.756 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.989 0.848 – 1.15 0.888 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.08 0.973 – 1.2 0.15 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 1.1 0.969 – 1.25 0.139 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.04 0.996 – 1.09 0.0709 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1 0.873 – 1.15 0.97 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.17 0.956 – 1.43 0.128 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.06 0.967 – 1.15 0.23 550 5509 all phecode
947 Urticaria Injuries & Poisonings 0.971 0.875 – 1.08 0.587 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 1 0.904 – 1.11 0.97 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.908 0.823 – 1 0.0577 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.962 0.85 – 1.09 0.545 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.02 0.926 – 1.12 0.728 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 0.704 0.544 – 0.912 0.00781 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.19 0.939 – 1.52 0.15 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.989 0.974 – 1 0.172 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.987 0.971 – 1 0.123 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1 0.908 – 1.11 0.932 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.03 0.965 – 1.11 0.34 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.02 0.916 – 1.13 0.721 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.02 0.919 – 1.14 0.668 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.949 0.828 – 1.09 0.456 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.02 0.898 – 1.15 0.805 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.03 0.906 – 1.16 0.688 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.982 0.957 – 1.01 0.177 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.06 0.994 – 1.12 0.0799 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.937 0.854 – 1.03 0.171 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.944 0.852 – 1.05 0.266 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1 0.917 – 1.1 0.947 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.982 0.902 – 1.07 0.671 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 0.979 0.934 – 1.03 0.365 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.923 0.796 – 1.07 0.292 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.925 0.816 – 1.05 0.221 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.773 0.616 – 0.971 0.0268 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 0.849 0.7 – 1.03 0.0989 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.1 0.898 – 1.35 0.36 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.875 0.681 – 1.12 0.296 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.01 0.78 – 1.3 0.953 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.995 0.871 – 1.14 0.936 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.07 0.988 – 1.15 0.0956 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.981 0.853 – 1.13 0.787 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.02 0.783 – 1.32 0.909 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 0.859 0.704 – 1.05 0.136 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 1.03 0.853 – 1.25 0.744 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.719 0.578 – 0.895 0.00308 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.02 0.986 – 1.06 0.222 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 0.994 0.957 – 1.03 0.741 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 0.994 0.957 – 1.03 0.741 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 0.985 0.963 – 1.01 0.178 8495 87394 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1 0.964 – 1.04 0.861 2632 26803 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.04 0.961 – 1.14 0.305 600 6430 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 0.917 0.853 – 0.985 0.0174 826 8503 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 0.882 0.668 – 1.17 0.379 54 545 exclusion phecode
010 Tuberculosis Infectious Diseases 1.11 0.94 – 1.3 0.221 160 1642 exclusion phecode
038 Septicemia Infectious Diseases 0.975 0.943 – 1.01 0.129 3851 41244 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.03 0.962 – 1.11 0.354 785 8411 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1 0.914 – 1.1 0.936 472 4920 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.02 1 – 1.04 0.0506 11464 118917 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.04 1 – 1.08 0.0512 2981 30975 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.05 0.999 – 1.11 0.0546 1550 16261 exclusion phecode
041.4 E. coli Infectious Diseases 0.996 0.957 – 1.04 0.855 2558 26972 exclusion phecode
053 Herpes zoster Infectious Diseases 1.02 0.919 – 1.13 0.725 390 4087 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.99 0.801 – 1.22 0.923 92 935 exclusion phecode
054 Herpes simplex Infectious Diseases 0.87 0.753 – 1.01 0.0588 206 2084 exclusion phecode
070 Viral hepatitis Infectious Diseases 0.988 0.907 – 1.08 0.773 580 5852 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.17 0.918 – 1.5 0.203 66 684 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 0.994 0.838 – 1.18 0.949 129 1317 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.01 0.891 – 1.15 0.861 253 2536 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.01 0.888 – 1.14 0.927 274 2735 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.07 0.964 – 1.18 0.206 415 4227 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.993 0.836 – 1.18 0.934 144 1455 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.973 0.8 – 1.18 0.78 114 1158 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.974 0.912 – 1.04 0.423 993 9923 exclusion phecode
079 Viral infection Infectious Diseases 0.995 0.956 – 1.04 0.805 2725 27415 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.904 0.703 – 1.16 0.433 64 635 exclusion phecode
080 Postoperative infection Infectious Diseases 1.01 0.98 – 1.04 0.491 4100 44279 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.02 0.979 – 1.07 0.331 2332 24511 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.918 0.724 – 1.16 0.482 71 699 exclusion phecode
1000 Burns Injuries & Poisonings 1.01 0.926 – 1.1 0.847 568 5742 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 0.969 0.913 – 1.03 0.3 1176 11879 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.02 0.992 – 1.05 0.156 5334 54060 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.02 0.902 – 1.14 0.801 293 2961 exclusion phecode
1005 Other symptoms Injuries & Poisonings 1.03 0.973 – 1.09 0.323 1368 14254 exclusion phecode
1006 Crushing injury Injuries & Poisonings 1 0.881 – 1.14 0.954 250 2524 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 1.02 0.899 – 1.16 0.745 250 2535 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 0.952 0.892 – 1.02 0.142 997 10006 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 1 0.979 – 1.02 0.884 8384 83847 exclusion phecode
1010 Other tests Injuries & Poisonings 1 0.976 – 1.03 0.807 5750 58724 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 0.995 0.973 – 1.02 0.625 8877 90349 exclusion phecode
1012 Late effect Injuries & Poisonings 1.08 0.884 – 1.31 0.468 104 1047 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.02 0.904 – 1.14 0.781 308 3131 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.09 0.842 – 1.41 0.51 66 651 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 0.99 0.958 – 1.02 0.546 3990 41815 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 0.997 0.98 – 1.01 0.699 15565 157227 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.956 0.846 – 1.08 0.465 276 2780 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.941 0.832 – 1.06 0.337 270 2718 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.24 0.978 – 1.57 0.0765 74 740 exclusion phecode
110.12 Althete's foot Infectious Diseases 0.891 0.753 – 1.05 0.178 140 1393 exclusion phecode
112 Candidiasis Infectious Diseases 1.01 0.969 – 1.06 0.542 2030 20973 exclusion phecode
117 Mycoses Infectious Diseases 0.919 0.809 – 1.04 0.193 260 2676 exclusion phecode
117.4 Aspergillosis Infectious Diseases 0.917 0.78 – 1.08 0.296 154 1622 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.954 0.762 – 1.19 0.682 79 792 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 1.01 0.79 – 1.29 0.931 69 680 exclusion phecode
134 Helminthiases Infectious Diseases 1.01 0.833 – 1.22 0.949 123 1252 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.06 0.864 – 1.29 0.596 103 1044 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.01 0.868 – 1.17 0.919 192 2023 exclusion phecode
145 Cancer of mouth Neoplasms 0.963 0.888 – 1.05 0.37 629 6333 exclusion phecode
145.2 Cancer of tongue Neoplasms 1 0.893 – 1.13 0.953 304 3062 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.989 0.81 – 1.21 0.912 103 1038 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 0.863 0.656 – 1.14 0.292 53 528 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.991 0.913 – 1.08 0.827 621 6244 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 0.973 0.854 – 1.11 0.676 247 2488 exclusion phecode
149.4 Cancer of larynx Neoplasms 0.987 0.869 – 1.12 0.839 256 2594 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.13 0.858 – 1.48 0.394 57 563 exclusion phecode
150 Cancer of esophagus Neoplasms 0.998 0.926 – 1.08 0.96 733 7630 exclusion phecode
151 Cancer of stomach Neoplasms 1.01 0.928 – 1.11 0.764 536 5696 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.999 0.9 – 1.11 0.986 373 4008 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.02 0.867 – 1.2 0.814 153 1580 exclusion phecode
157 Pancreatic cancer Neoplasms 1.11 1.02 – 1.21 0.0124 634 6582 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.28 1.19 – 1.38 5.24e-11 757 10635 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.17 1.12 – 1.22 1.63e-13 2386 55694 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.1 0.932 – 1.3 0.255 143 1900 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.13 0.975 – 1.3 0.107 196 2048 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.982 0.842 – 1.14 0.813 179 1925 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 0.948 0.727 – 1.24 0.693 57 588 exclusion phecode
165 Cancer within the respiratory system Neoplasms 0.976 0.938 – 1.02 0.237 2668 27750 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 0.98 0.937 – 1.02 0.367 2137 21929 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 0.937 0.848 – 1.04 0.203 424 4307 exclusion phecode
170.1 Bone cancer Neoplasms 0.973 0.816 – 1.16 0.765 126 1289 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 0.952 0.849 – 1.07 0.399 322 3261 exclusion phecode
172 Skin cancer Neoplasms 1 0.986 – 1.02 0.686 13209 132968 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1 0.96 – 1.04 0.988 2635 26421 exclusion phecode
172.11 Melanomas of skin Neoplasms 1 0.962 – 1.04 0.963 2666 26742 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1 0.983 – 1.02 0.793 10757 108400 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 1.01 0.933 – 1.1 0.773 651 6550 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.989 0.851 – 1.15 0.882 179 1795 exclusion phecode
174 Breast cancer Neoplasms 1.04 1.02 – 1.06 0.000137 12502 125331 exclusion phecode
174.1 Breast cancer [female] Neoplasms 1.03 1.02 – 1.05 0.000314 12308 123270 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.03 1.01 – 1.05 0.000725 11592 116348 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.959 0.788 – 1.17 0.674 112 1139 exclusion phecode
175 Acquired absence of breast Neoplasms 0.996 0.955 – 1.04 0.868 2365 23792 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 0.995 0.952 – 1.04 0.84 2157 21622 exclusion phecode
180.1 Cervical cancer Neoplasms 1.05 0.929 – 1.19 0.425 268 2693 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.985 0.941 – 1.03 0.524 2063 20665 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.994 0.938 – 1.05 0.842 1251 12686 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.03 0.977 – 1.09 0.249 1322 13651 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.03 0.966 – 1.11 0.335 932 9583 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.04 0.972 – 1.11 0.251 906 9307 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.04 0.924 – 1.18 0.488 288 3023 exclusion phecode
185 Cancer of prostate Neoplasms 1.02 0.99 – 1.05 0.207 5838 57680 exclusion phecode
187 Cancer of other male genital organs Neoplasms 1.02 0.923 – 1.12 0.74 442 4431 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.22 0.955 – 1.57 0.111 67 683 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.979 0.866 – 1.11 0.727 286 2844 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.02 0.841 – 1.24 0.823 108 1082 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.997 0.965 – 1.03 0.846 3990 40952 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.04 0.971 – 1.1 0.284 1027 10584 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.04 0.973 – 1.11 0.257 988 10192 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.18 0.922 – 1.51 0.188 65 650 exclusion phecode
189.2 Cancer of bladder Neoplasms 0.986 0.945 – 1.03 0.506 2340 23718 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.978 0.934 – 1.02 0.324 2079 21082 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.02 0.859 – 1.22 0.794 135 1411 exclusion phecode
190 Cancer of eye Neoplasms 1.06 0.911 – 1.24 0.432 173 1738 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.919 0.849 – 0.994 0.0359 674 6779 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.913 0.837 – 0.996 0.0403 555 5559 exclusion phecode
191.11 Cancer of brain Neoplasms 0.93 0.85 – 1.02 0.115 516 5159 exclusion phecode
193 Thyroid cancer Neoplasms 0.96 0.859 – 1.07 0.475 339 3437 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.1 0.89 – 1.35 0.389 93 939 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.07 1.06 – 1.09 1.44e-17 15990 164445 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.08 1.06 – 1.1 1.48e-18 15320 158505 exclusion phecode
197 Chemotherapy Neoplasms 1 0.988 – 1.02 0.703 19481 212080 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.01 0.984 – 1.03 0.536 7798 94938 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.01 0.977 – 1.04 0.629 4360 53408 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.976 0.93 – 1.02 0.32 1757 22549 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.01 0.954 – 1.07 0.68 1183 15389 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.01 0.96 – 1.05 0.794 1870 26463 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.94 0.873 – 1.01 0.0999 777 8433 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 0.969 0.925 – 1.01 0.173 2018 21458 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.954 0.812 – 1.12 0.571 166 1881 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.02 0.965 – 1.08 0.488 1380 14212 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.03 0.834 – 1.26 0.801 92 942 exclusion phecode
200 Myeloproliferative disease Neoplasms 1 0.939 – 1.07 0.936 969 9766 exclusion phecode
200.1 Polycythemia vera Neoplasms 1 0.902 – 1.11 0.985 381 3808 exclusion phecode
201 Hodgkin's disease Neoplasms 0.901 0.792 – 1.03 0.113 246 2569 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1 0.962 – 1.05 0.839 2199 22418 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.02 0.974 – 1.07 0.376 1753 17830 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.13 1.01 – 1.26 0.0303 354 3602 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.02 0.935 – 1.11 0.646 562 5740 exclusion phecode
204 Leukemia Neoplasms 0.962 0.914 – 1.01 0.133 1634 16378 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 0.971 0.892 – 1.06 0.504 570 5705 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.78 0.595 – 1.02 0.0721 55 556 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.986 0.9 – 1.08 0.76 501 5010 exclusion phecode
204.2 Myeloid leukemia Neoplasms 0.887 0.805 – 0.977 0.0151 453 4559 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 0.865 0.771 – 0.972 0.0146 323 3234 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.983 0.829 – 1.16 0.84 141 1422 exclusion phecode
204.4 Multiple myeloma Neoplasms 1.01 0.925 – 1.1 0.832 546 5458 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1.29 1.27 – 1.31 3.02e-231 18064 191891 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.04 0.977 – 1.11 0.211 966 9671 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.04 1.01 – 1.07 0.0105 5106 52452 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.992 0.889 – 1.11 0.892 341 3417 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.03 0.917 – 1.16 0.617 313 3152 exclusion phecode
214 Lipoma Neoplasms 1.02 0.991 – 1.04 0.197 6151 61588 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.01 0.981 – 1.04 0.481 4537 45364 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.03 0.968 – 1.1 0.348 1090 10923 exclusion phecode
216 Benign neoplasm of skin Neoplasms 1.01 0.984 – 1.03 0.518 7554 75841 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.06 0.973 – 1.15 0.189 608 6236 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 1.05 0.961 – 1.14 0.296 571 5874 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.994 0.974 – 1.01 0.56 9901 99452 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 0.996 0.976 – 1.02 0.693 10113 101582 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.02 0.915 – 1.13 0.743 349 3517 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 1.02 0.967 – 1.08 0.456 1414 14351 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.02 0.887 – 1.17 0.803 215 2175 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 1.06 0.906 – 1.25 0.449 160 1580 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.01 0.861 – 1.18 0.94 170 1702 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.967 0.802 – 1.17 0.723 128 1278 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.02 0.789 – 1.32 0.874 66 668 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.978 0.909 – 1.05 0.548 806 8069 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.971 0.902 – 1.05 0.444 765 7681 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.18 0.907 – 1.53 0.219 59 583 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.11 0.975 – 1.26 0.117 261 2640 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.03 0.957 – 1.1 0.462 845 8528 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.03 0.887 – 1.2 0.68 182 1835 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.05 0.945 – 1.17 0.36 364 3668 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.98 0.872 – 1.1 0.733 306 3082 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.05 1 – 1.11 0.0481 1558 15768 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.03 0.988 – 1.07 0.158 2367 23719 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.945 0.868 – 1.03 0.189 590 5935 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.994 0.933 – 1.06 0.845 1075 10961 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.04 0.943 – 1.14 0.447 460 4657 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.982 0.907 – 1.06 0.657 653 6696 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.06 1.01 – 1.11 0.02 1811 18310 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 1.12 1.02 – 1.23 0.0234 449 4503 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.06 0.858 – 1.32 0.577 88 899 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.995 0.836 – 1.18 0.954 138 1357 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.01 0.988 – 1.02 0.537 14328 143391 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.02 0.956 – 1.08 0.581 1076 10961 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.907 0.74 – 1.11 0.35 98 1003 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.01 0.988 – 1.02 0.523 13672 137320 exclusion phecode
245 Thyroiditis Endocrine/metabolic 1.07 0.948 – 1.21 0.27 284 2855 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.08 0.944 – 1.24 0.252 215 2160 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.03 0.892 – 1.19 0.695 207 2083 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 0.978 0.883 – 1.08 0.676 390 3926 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.01 0.995 – 1.03 0.173 19293 183496 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.03 0.992 – 1.07 0.123 2687 27287 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.966 0.85 – 1.1 0.599 235 2365 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.868 0.681 – 1.11 0.252 75 755 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.08 0.983 – 1.19 0.108 466 4692 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.02 0.871 – 1.2 0.788 160 1592 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.01 0.995 – 1.03 0.199 17377 167829 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.746 0.611 – 0.91 0.00382 100 1038 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.982 0.845 – 1.14 0.808 197 1983 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.06 0.995 – 1.14 0.0702 961 9758 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 0.944 0.861 – 1.04 0.222 492 4991 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.02 0.942 – 1.11 0.614 669 6739 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.11 0.98 – 1.27 0.0975 263 2623 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.965 0.871 – 1.07 0.493 407 4131 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.05 0.879 – 1.25 0.606 129 1301 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.988 0.885 – 1.1 0.83 342 3435 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.05 0.992 – 1.11 0.0917 1301 13140 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1 0.938 – 1.07 0.912 902 9231 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.05 0.982 – 1.13 0.143 848 8610 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.05 0.974 – 1.13 0.207 759 7703 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.06 0.886 – 1.26 0.547 135 1402 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.02 0.941 – 1.1 0.652 669 6737 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.984 0.848 – 1.14 0.833 185 1843 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.01 0.828 – 1.24 0.888 93 933 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.04 0.912 – 1.18 0.581 256 2592 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.972 0.785 – 1.2 0.796 92 909 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.01 0.86 – 1.19 0.887 152 1551 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.99 0.912 – 1.07 0.806 620 6307 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1 0.859 – 1.17 0.972 177 1780 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.926 0.752 – 1.14 0.47 100 1022 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.11 0.881 – 1.4 0.372 76 746 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.92 0.825 – 1.03 0.134 353 3579 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.917 0.822 – 1.02 0.119 352 3570 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.974 0.853 – 1.11 0.702 238 2393 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.01 0.874 – 1.17 0.898 208 2084 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 0.871 0.74 – 1.02 0.0945 157 1594 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.888 0.752 – 1.05 0.164 149 1515 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.94 0.77 – 1.15 0.54 101 1015 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 0.946 0.802 – 1.12 0.513 148 1489 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.917 0.788 – 1.07 0.263 188 1997 exclusion phecode
260.6 Anorexia Endocrine/metabolic 0.947 0.88 – 1.02 0.138 786 8180 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.05 0.988 – 1.11 0.118 1179 11836 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.03 0.951 – 1.11 0.515 745 7446 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.07 0.972 – 1.18 0.167 437 4411 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.881 0.696 – 1.12 0.296 76 758 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.962 0.845 – 1.1 0.561 234 2376 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.12 0.997 – 1.25 0.0571 328 3317 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.948 0.842 – 1.07 0.378 295 2971 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.925 0.814 – 1.05 0.231 254 2555 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 0.914 0.788 – 1.06 0.235 188 1868 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1.06 0.874 – 1.29 0.538 112 1102 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 0.866 0.664 – 1.13 0.286 64 684 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.975 0.827 – 1.15 0.76 156 1585 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.956 0.803 – 1.14 0.614 135 1380 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.997 0.986 – 1.01 0.595 34037 232536 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.997 0.986 – 1.01 0.606 33968 232306 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.998 0.986 – 1.01 0.73 31573 225230 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.901 0.694 – 1.17 0.433 58 570 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.991 0.842 – 1.17 0.912 157 1615 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.959 0.835 – 1.1 0.551 209 2082 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.962 0.93 – 0.996 0.0285 3633 36600 exclusion phecode
274.1 Gout Endocrine/metabolic 0.967 0.932 – 1 0.0808 3084 31159 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.871 0.716 – 1.06 0.167 108 1103 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.965 0.888 – 1.05 0.393 609 6039 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.956 0.877 – 1.04 0.306 555 5498 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.03 0.979 – 1.07 0.283 2020 20748 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 0.998 0.92 – 1.08 0.961 645 6434 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 0.972 0.868 – 1.09 0.617 338 3690 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.04 0.983 – 1.11 0.158 1141 11841 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.04 0.883 – 1.21 0.67 156 1693 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 0.998 0.974 – 1.02 0.901 6812 71953 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.01 0.975 – 1.04 0.646 3853 40361 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.962 0.837 – 1.11 0.587 223 2370 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.03 0.978 – 1.08 0.278 1741 17944 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.01 0.941 – 1.08 0.84 903 9573 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1 0.95 – 1.06 0.88 1321 14062 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 0.982 0.923 – 1.05 0.568 1082 11481 exclusion phecode
276.41 Acidosis Endocrine/metabolic 0.979 0.917 – 1.05 0.525 987 10442 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.08 0.88 – 1.33 0.451 102 1110 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 0.981 0.943 – 1.02 0.359 2584 27894 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.09 0.986 – 1.2 0.0932 432 4455 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 0.861 0.717 – 1.03 0.109 127 1265 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.01 0.941 – 1.08 0.795 853 8875 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.934 0.835 – 1.04 0.227 347 3565 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.968 0.844 – 1.11 0.639 227 2263 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.07 0.798 – 1.42 0.669 52 513 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.999 0.98 – 1.02 0.953 10578 107020 exclusion phecode
278.1 Obesity Endocrine/metabolic 0.998 0.978 – 1.02 0.86 10416 105413 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 1.01 0.814 – 1.26 0.907 84 831 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.14 0.899 – 1.44 0.281 66 658 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.11 0.975 – 1.27 0.115 248 2480 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.06 0.918 – 1.22 0.425 207 2076 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.1 0.92 – 1.31 0.303 137 1374 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.05 0.924 – 1.19 0.451 245 2414 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.01 0.984 – 1.03 0.52 7238 75317 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.01 0.982 – 1.03 0.625 6942 72331 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.01 0.915 – 1.11 0.862 440 4495 exclusion phecode
281 Other deficiency anemia Hematopoietic 0.994 0.935 – 1.06 0.859 1088 10992 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.01 0.945 – 1.07 0.838 1043 10542 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.02 0.949 – 1.1 0.556 736 7425 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.93 0.799 – 1.08 0.349 173 1756 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 1.05 0.895 – 1.23 0.555 177 1808 exclusion phecode
281.9 Deficiency anemias Hematopoietic 0.873 0.666 – 1.14 0.325 53 532 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 0.985 0.83 – 1.17 0.86 145 1488 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1 0.767 – 1.31 0.994 53 556 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.972 0.783 – 1.21 0.801 84 838 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 0.954 0.797 – 1.14 0.604 132 1362 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.02 0.836 – 1.26 0.814 101 1049 exclusion phecode
284 Aplastic anemia Hematopoietic 1.01 0.913 – 1.11 0.887 420 4307 exclusion phecode
285 Other anemias Hematopoietic 1 0.984 – 1.02 0.784 11488 119691 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.07 0.949 – 1.22 0.256 266 2682 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.04 0.956 – 1.13 0.377 619 6877 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.988 0.885 – 1.1 0.835 340 4081 exclusion phecode
286 Coagulation defects Hematopoietic 0.989 0.923 – 1.06 0.748 897 9102 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.952 0.864 – 1.05 0.321 448 4552 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.953 0.773 – 1.18 0.654 93 950 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.934 0.828 – 1.05 0.27 287 2916 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.06 0.824 – 1.37 0.633 62 624 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.93 0.75 – 1.15 0.511 84 843 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.02 0.913 – 1.13 0.779 377 3816 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.986 0.936 – 1.04 0.583 1569 16298 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.14 0.948 – 1.38 0.16 124 1273 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 0.979 0.928 – 1.03 0.435 1475 15331 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.03 0.927 – 1.13 0.624 410 4136 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.03 0.8 – 1.32 0.839 71 737 exclusion phecode
288 Diseases of white blood cells Hematopoietic 0.967 0.934 – 1 0.0611 3478 37210 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 0.971 0.935 – 1.01 0.134 2910 31310 exclusion phecode
288.11 Neutropenia Hematopoietic 0.972 0.935 – 1.01 0.138 2918 31392 exclusion phecode
288.3 Eosinophilia Hematopoietic 0.913 0.716 – 1.16 0.462 71 699 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.973 0.907 – 1.04 0.44 843 8510 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.99 0.875 – 1.12 0.876 281 2866 exclusion phecode
289.4 Lymphadenitis Hematopoietic 0.989 0.95 – 1.03 0.612 2475 25717 exclusion phecode
289.5 Diseases of spleen Hematopoietic 0.972 0.887 – 1.07 0.546 493 5081 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.03 0.911 – 1.16 0.649 284 2878 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 0.842 0.672 – 1.06 0.136 88 890 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.995 0.949 – 1.04 0.848 1865 18970 exclusion phecode
290.1 Dementias Mental Disorders 0.984 0.922 – 1.05 0.631 982 9864 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.952 0.862 – 1.05 0.33 424 4231 exclusion phecode
290.16 Vascular dementia Mental Disorders 1.06 0.912 – 1.23 0.457 194 1978 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.03 0.952 – 1.12 0.429 619 6385 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.05 0.835 – 1.33 0.654 70 699 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.994 0.926 – 1.07 0.874 816 8266 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.14 0.956 – 1.37 0.143 131 1306 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.934 0.828 – 1.05 0.269 278 2829 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 0.994 0.901 – 1.1 0.9 425 4314 exclusion phecode
292 Neurological disorders Mental Disorders 1.02 0.986 – 1.05 0.287 4494 45554 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.02 0.962 – 1.07 0.57 1473 14854 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.979 0.841 – 1.14 0.78 182 1877 exclusion phecode
292.3 Memory loss Mental Disorders 1.01 0.937 – 1.1 0.726 686 6885 exclusion phecode
292.4 Altered mental status Mental Disorders 1.03 0.985 – 1.08 0.191 2111 21468 exclusion phecode
292.6 Hallucinations Mental Disorders 0.944 0.839 – 1.06 0.334 295 3032 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.03 0.988 – 1.08 0.151 2057 20513 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.03 0.959 – 1.1 0.443 889 8891 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.11 1.03 – 1.19 0.00418 831 8363 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.13 1.04 – 1.24 0.00427 568 5711 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.01 0.865 – 1.18 0.891 174 1759 exclusion phecode
295.3 Psychosis Mental Disorders 1.02 0.874 – 1.2 0.783 168 1691 exclusion phecode
296 Mood disorders Mental Disorders 1.01 0.989 – 1.03 0.424 12179 122724 exclusion phecode
296.1 Bipolar Mental Disorders 1.01 0.953 – 1.08 0.645 1045 10509 exclusion phecode
296.2 Depression Mental Disorders 1.01 0.987 – 1.03 0.503 11553 116440 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.01 0.903 – 1.12 0.908 358 3576 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.09 0.969 – 1.23 0.151 304 3043 exclusion phecode
300 Anxiety disorders Mental Disorders 1.01 0.981 – 1.03 0.649 6719 67797 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.01 0.985 – 1.04 0.413 6200 62650 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 0.963 0.817 – 1.13 0.652 148 1491 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.995 0.92 – 1.08 0.906 697 6995 exclusion phecode
300.13 Phobia Mental Disorders 1.01 0.923 – 1.11 0.787 490 4970 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.2 1 – 1.43 0.0496 140 1396 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 0.919 0.7 – 1.2 0.539 53 526 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 0.944 0.789 – 1.13 0.528 123 1232 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.882 0.73 – 1.07 0.195 112 1121 exclusion phecode
301 Personality disorders Mental Disorders 0.934 0.833 – 1.05 0.247 332 3318 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.935 0.772 – 1.13 0.493 118 1183 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 1.17 1.04 – 1.33 0.0123 277 2812 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.08 0.981 – 1.19 0.115 461 4648 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 1.09 0.976 – 1.22 0.126 345 3482 exclusion phecode
303.4 Somatoform disorder Mental Disorders 1.04 0.865 – 1.25 0.67 120 1218 exclusion phecode
304 Adjustment reaction Mental Disorders 0.967 0.858 – 1.09 0.584 292 2914 exclusion phecode
305.2 Eating disorder Mental Disorders 1.03 0.827 – 1.27 0.814 88 896 exclusion phecode
306 Other mental disorder Mental Disorders 0.994 0.982 – 1.01 0.35 27163 227483 exclusion phecode
306.9 Tension headache Mental Disorders 1.06 0.941 – 1.19 0.353 311 3114 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 1.29 1.03 – 1.62 0.0294 75 766 exclusion phecode
313.3 Autism Mental Disorders 1.38 1.05 – 1.81 0.0202 52 536 exclusion phecode
315 Develomental delays and disorders Mental Disorders 0.989 0.885 – 1.1 0.844 337 3475 exclusion phecode
315.1 Learning disorder Mental Disorders 1.11 0.945 – 1.31 0.201 160 1597 exclusion phecode
315.2 Speech and language disorder Mental Disorders 1.08 0.862 – 1.34 0.518 85 864 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.02 0.991 – 1.05 0.183 5190 52523 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.01 0.989 – 1.03 0.409 12426 125398 exclusion phecode
317.1 Alcoholism Mental Disorders 1 0.982 – 1.03 0.711 8684 87835 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.02 0.946 – 1.09 0.67 818 8274 exclusion phecode
318 Tobacco use disorder Mental Disorders 1 0.988 – 1.02 0.667 18953 183403 exclusion phecode
320 Meningitis Neurological 1.09 0.987 – 1.2 0.0898 439 4390 exclusion phecode
323 Encephalitis Neurological 1.02 0.915 – 1.14 0.703 339 3381 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 1.06 0.833 – 1.34 0.65 74 734 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 0.999 0.886 – 1.13 0.983 286 2871 exclusion phecode
327 Sleep disorders Neurological 0.965 0.909 – 1.03 0.253 1149 11499 exclusion phecode
327.3 Sleep apnea Neurological 1.01 0.982 – 1.04 0.427 4357 43713 exclusion phecode
327.4 Insomnia Neurological 0.972 0.829 – 1.14 0.728 161 1641 exclusion phecode
327.41 Organic or persistent insomnia Neurological 0.982 0.823 – 1.17 0.843 134 1374 exclusion phecode
331 Other cerebral degenerations Neurological 0.983 0.925 – 1.04 0.582 1114 11276 exclusion phecode
331.1 Hydrocephalus Neurological 0.957 0.873 – 1.05 0.353 490 4959 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 0.976 0.884 – 1.08 0.633 418 4242 exclusion phecode
332 Parkinson's disease Neurological 0.991 0.932 – 1.05 0.771 1103 11044 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.948 0.884 – 1.02 0.134 868 8821 exclusion phecode
333.1 Essential tremor Neurological 0.939 0.814 – 1.08 0.391 206 2126 exclusion phecode
333.2 Myoclonus Neurological 0.882 0.713 – 1.09 0.246 90 945 exclusion phecode
333.4 Torsion dystonia Neurological 0.9 0.789 – 1.03 0.114 251 2500 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 0.952 0.907 – 0.999 0.0458 1785 17892 exclusion phecode
334.1 Spinocerebellar disease Neurological 0.874 0.73 – 1.05 0.145 116 1151 exclusion phecode
334.2 Anterior horn cell disease Neurological 0.908 0.794 – 1.04 0.162 243 2410 exclusion phecode
335 Multiple sclerosis Neurological 0.892 0.843 – 0.944 7.44e-05 1324 13257 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.04 0.912 – 1.18 0.572 264 2631 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.07 0.842 – 1.37 0.569 72 708 exclusion phecode
338 Pain Neurological 0.967 0.895 – 1.04 0.384 721 7598 exclusion phecode
338.1 Acute pain Neurological 0.946 0.848 – 1.05 0.314 356 3895 exclusion phecode
338.2 Chronic pain Neurological 0.973 0.875 – 1.08 0.608 371 3783 exclusion phecode
339 Other headache syndromes Neurological 1 0.981 – 1.03 0.743 7724 77415 exclusion phecode
340 Migraine Neurological 0.988 0.951 – 1.03 0.552 2817 28344 exclusion phecode
340.1 Migrain with aura Neurological 0.969 0.842 – 1.11 0.655 210 2096 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.981 0.862 – 1.11 0.764 249 2508 exclusion phecode
342 Hemiplegia Neurological 0.954 0.904 – 1.01 0.0812 1463 14728 exclusion phecode
343 Infantile cerebral palsy Neurological 1.03 0.871 – 1.22 0.713 142 1434 exclusion phecode
344 Other paralytic syndromes Neurological 1.02 0.942 – 1.11 0.599 644 6510 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.971 0.943 – 1 0.048 4939 49686 exclusion phecode
345.1 Epilepsy Neurological 0.959 0.893 – 1.03 0.238 848 8548 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.01 0.914 – 1.11 0.864 429 4325 exclusion phecode
345.12 Partial epilepsy Neurological 1.02 0.903 – 1.15 0.746 271 2753 exclusion phecode
345.3 Convulsions Neurological 0.964 0.923 – 1.01 0.0982 2192 22047 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.931 0.785 – 1.11 0.416 141 1420 exclusion phecode
348 Other conditions of brain Neurological 0.959 0.89 – 1.03 0.273 764 7720 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.03 0.906 – 1.17 0.669 265 2651 exclusion phecode
348.4 Cerebral cysts Neurological 0.868 0.728 – 1.03 0.113 131 1338 exclusion phecode
348.7 Coma Neurological 1.01 0.903 – 1.13 0.877 350 3538 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 0.954 0.837 – 1.09 0.487 241 2469 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.08 0.968 – 1.2 0.173 379 3847 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.02 0.911 – 1.14 0.747 339 3378 exclusion phecode
350 Abnormal movement Neurological 1.05 1.01 – 1.09 0.0208 2611 26328 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.04 0.968 – 1.11 0.304 869 8739 exclusion phecode
350.2 Abnormality of gait Neurological 1.04 0.992 – 1.1 0.0977 1554 15741 exclusion phecode
350.3 Lack of coordination Neurological 1.08 0.974 – 1.2 0.143 359 3579 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.986 0.754 – 1.29 0.917 53 534 exclusion phecode
351 Other peripheral nerve disorders Neurological 0.986 0.968 – 1 0.14 12280 122908 exclusion phecode
352 Disorders of other cranial nerves Neurological 1 0.949 – 1.06 0.928 1354 13515 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.969 0.881 – 1.07 0.524 459 4588 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 0.999 0.932 – 1.07 0.987 869 8659 exclusion phecode
353 Nerve root and plexus disorders Neurological 1 0.942 – 1.07 0.958 1108 11170 exclusion phecode
353.1 Nerve plexus lesions Neurological 1.02 0.837 – 1.23 0.868 114 1124 exclusion phecode
353.2 Nerve root lesions Neurological 0.992 0.764 – 1.29 0.951 57 560 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.844 0.713 – 1 0.0506 149 1496 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.02 0.963 – 1.08 0.499 1296 13459 exclusion phecode
358 Myoneural disorders Neurological 1.01 0.872 – 1.16 0.93 206 2085 exclusion phecode
358.1 Myasthenia gravis Neurological 0.981 0.847 – 1.14 0.795 188 1896 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 1.04 0.94 – 1.14 0.469 452 4577 exclusion phecode
359.1 Muscular dystrophies Neurological 1 0.831 – 1.21 0.979 119 1204 exclusion phecode
359.2 Myopathy Neurological 1.03 0.921 – 1.15 0.601 350 3550 exclusion phecode
360 Disorders of the globe Sense Organs 0.999 0.893 – 1.12 0.982 331 3319 exclusion phecode
360.2 Progressive myopia Sense Organs 0.995 0.874 – 1.13 0.944 246 2472 exclusion phecode
361 Retinal detachments and defects Sense Organs 1 0.969 – 1.04 0.814 3196 31977 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.99 0.937 – 1.05 0.732 1364 13687 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 1.01 0.789 – 1.28 0.963 67 675 exclusion phecode
362 Other retinal disorders Sense Organs 1.01 0.972 – 1.04 0.752 3768 37741 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.993 0.95 – 1.04 0.768 2137 21443 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.993 0.95 – 1.04 0.75 2134 21415 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.07 0.911 – 1.26 0.402 158 1589 exclusion phecode
362.31 Separation of retinal layers Sense Organs 0.992 0.808 – 1.22 0.942 97 974 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.995 0.927 – 1.07 0.89 835 8355 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 1.16 0.99 – 1.35 0.0667 180 1796 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.09 0.861 – 1.38 0.479 81 800 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.13 0.93 – 1.36 0.226 112 1139 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.917 0.784 – 1.07 0.28 170 1672 exclusion phecode
363.3 Chorioretinal scars Sense Organs 1.02 0.801 – 1.31 0.851 69 681 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.982 0.907 – 1.06 0.658 644 6400 exclusion phecode
364.1 Corneal opacity Sense Organs 1.06 0.841 – 1.32 0.643 87 899 exclusion phecode
364.2 Corneal edema Sense Organs 0.898 0.714 – 1.13 0.356 78 789 exclusion phecode
364.4 Corneal degenerations Sense Organs 0.928 0.805 – 1.07 0.308 201 1988 exclusion phecode
364.41 Keratoconus Sense Organs 0.976 0.781 – 1.22 0.829 86 858 exclusion phecode
364.5 Corneal dystrophy Sense Organs 1.02 0.889 – 1.17 0.794 210 2083 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.967 0.793 – 1.18 0.736 100 994 exclusion phecode
365 Glaucoma Sense Organs 1.01 0.978 – 1.04 0.557 4300 43418 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 1.01 0.948 – 1.08 0.733 1008 10146 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 1.01 0.951 – 1.08 0.666 1003 10086 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.05 0.969 – 1.13 0.239 685 6884 exclusion phecode
366 Cataract Sense Organs 0.991 0.977 – 1.01 0.252 19569 166144 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 0.942 0.731 – 1.21 0.644 66 690 exclusion phecode
366.2 Senile cataract Sense Organs 1 0.98 – 1.03 0.786 8078 80523 exclusion phecode
366.3 Traumatic cataract Sense Organs 0.803 0.658 – 0.981 0.0315 100 999 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.992 0.951 – 1.03 0.695 2367 23723 exclusion phecode
367.1 Myopia Sense Organs 0.958 0.904 – 1.02 0.15 1232 12338 exclusion phecode
367.2 Astigmatism Sense Organs 0.962 0.83 – 1.12 0.608 187 1874 exclusion phecode
367.8 Hypermetropia Sense Organs 1.03 0.905 – 1.17 0.654 249 2480 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.08 1 – 1.17 0.0465 702 7091 exclusion phecode
368 Visual disturbances Sense Organs 0.987 0.95 – 1.03 0.505 2914 29261 exclusion phecode
368.1 Amblyopia Sense Organs 1.09 0.996 – 1.19 0.0625 527 5249 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.979 0.906 – 1.06 0.589 718 7202 exclusion phecode
368.3 Anisometropia Sense Organs 1 0.85 – 1.18 0.991 151 1526 exclusion phecode
368.4 Visual field defects Sense Organs 0.954 0.853 – 1.07 0.412 327 3279 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 1.01 0.93 – 1.1 0.799 602 6036 exclusion phecode
369 Infection of the eye Sense Organs 1.04 0.957 – 1.14 0.332 541 5470 exclusion phecode
369.2 Eye infection, viral Sense Organs 1.12 0.928 – 1.35 0.241 122 1241 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.951 0.825 – 1.1 0.482 208 2097 exclusion phecode
370 Keratitis Sense Organs 0.851 0.752 – 0.963 0.0106 280 2832 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.855 0.718 – 1.02 0.0818 139 1394 exclusion phecode
371 Inflammation of the eye Sense Organs 0.973 0.937 – 1.01 0.157 3006 30117 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.93 0.846 – 1.02 0.132 480 4776 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.96 0.92 – 1 0.0662 2322 23285 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.07 0.989 – 1.15 0.0937 746 7516 exclusion phecode
374 Other disorders of eyelids Sense Organs 1.02 0.992 – 1.05 0.158 5600 55994 exclusion phecode
374.1 Ectropion or entropion Sense Organs 1.01 0.949 – 1.08 0.716 1050 10447 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 1.01 0.966 – 1.06 0.57 1804 17959 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.979 0.936 – 1.02 0.337 2172 21695 exclusion phecode
375.2 Epiphora Sense Organs 0.97 0.904 – 1.04 0.388 882 8819 exclusion phecode
376 Disorders of the orbit Sense Organs 0.98 0.778 – 1.23 0.862 85 849 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.957 0.859 – 1.07 0.423 359 3573 exclusion phecode
377.1 Optic atrophy Sense Organs 0.896 0.686 – 1.17 0.419 55 565 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.14 0.942 – 1.37 0.182 125 1235 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.07 1.01 – 1.13 0.0164 1383 13939 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.06 0.992 – 1.14 0.086 898 8975 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.1 0.955 – 1.26 0.189 206 2099 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.07 0.948 – 1.22 0.26 268 2724 exclusion phecode
379 Other disorders of eye Sense Organs 0.983 0.951 – 1.02 0.338 3638 36465 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.968 0.916 – 1.02 0.25 1352 13458 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.99 0.942 – 1.04 0.68 1766 17809 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.14 0.898 – 1.45 0.279 70 704 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.946 0.852 – 1.05 0.293 395 3972 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.09 0.93 – 1.27 0.293 167 1673 exclusion phecode
380 Disorders of external ear Sense Organs 1.04 0.961 – 1.13 0.308 626 6333 exclusion phecode
380.1 Otitis externa Sense Organs 1.02 0.927 – 1.12 0.717 502 5056 exclusion phecode
380.4 Impacted cerumen Sense Organs 1.05 0.942 – 1.17 0.372 356 3569 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.984 0.941 – 1.03 0.491 2114 21221 exclusion phecode
381.1 Otitis media Sense Organs 0.979 0.932 – 1.03 0.394 1738 17429 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.979 0.912 – 1.05 0.553 843 8420 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 1 0.862 – 1.16 0.996 190 1912 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 1.03 0.883 – 1.21 0.678 167 1687 exclusion phecode
381.9 Otorrhea Sense Organs 0.939 0.829 – 1.06 0.324 273 2771 exclusion phecode
382 Otalgia Sense Organs 0.97 0.86 – 1.09 0.621 300 3043 exclusion phecode
383 Otosclerosis Sense Organs 1.02 0.907 – 1.15 0.747 307 3054 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.05 0.987 – 1.11 0.126 1273 12828 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.05 0.985 – 1.12 0.13 1021 10290 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.02 0.947 – 1.1 0.594 775 7717 exclusion phecode
385.3 Cholesteatoma Sense Organs 0.974 0.896 – 1.06 0.537 599 5982 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.06 0.928 – 1.21 0.392 239 2376 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.01 0.958 – 1.06 0.781 1700 17116 exclusion phecode
386.1 Meniere's disease Sense Organs 1.04 0.958 – 1.14 0.332 559 5686 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.946 0.85 – 1.05 0.313 369 3701 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.02 0.944 – 1.1 0.646 752 7547 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.01 0.976 – 1.04 0.666 4471 45240 exclusion phecode
388 Other disorders of ear Sense Organs 1.18 1.02 – 1.37 0.025 197 1991 exclusion phecode
389 Hearing loss Sense Organs 0.971 0.94 – 1 0.0723 4102 41321 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.903 0.82 – 0.996 0.0408 447 4484 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.03 0.932 – 1.13 0.604 446 4446 exclusion phecode
389.4 Tinnitus Sense Organs 1.04 0.952 – 1.15 0.358 499 5074 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 0.99 0.961 – 1.02 0.511 4787 48132 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.01 0.974 – 1.05 0.529 2925 29441 exclusion phecode
394.3 Aortic valve disease Circulatory System 0.973 0.918 – 1.03 0.363 1248 12576 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 0.98 0.919 – 1.04 0.526 1035 10405 exclusion phecode
395 Heart valve disorders Circulatory System 0.994 0.962 – 1.03 0.698 4123 41513 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.01 0.974 – 1.05 0.521 2826 28429 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.965 0.851 – 1.09 0.583 266 2722 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.09 0.887 – 1.33 0.42 103 1025 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.92 0.748 – 1.13 0.428 94 957 exclusion phecode
395.6 Heart valve replaced Circulatory System 0.964 0.913 – 1.02 0.177 1461 14672 exclusion phecode
396 Abnormal heart sounds Circulatory System 1 0.942 – 1.07 0.899 1025 10339 exclusion phecode
401 Hypertension Circulatory System 1 0.992 – 1.01 0.999 72288 264574 exclusion phecode
401.1 Essential hypertension Circulatory System 1 0.991 – 1.01 0.964 72067 264358 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.01 0.96 – 1.06 0.755 1839 18778 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.11 0.999 – 1.24 0.0516 364 3643 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.991 0.939 – 1.05 0.744 1490 15282 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.01 0.855 – 1.2 0.883 143 1421 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.03 0.975 – 1.08 0.305 1450 14621 exclusion phecode
411 Ischemic Heart Disease Circulatory System 0.981 0.969 – 0.993 0.00177 30641 207900 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.965 0.938 – 0.994 0.0165 5062 50694 exclusion phecode
411.2 Myocardial infarction Circulatory System 0.984 0.966 – 1 0.101 11720 110918 exclusion phecode
411.3 Angina pectoris Circulatory System 0.981 0.965 – 0.998 0.0259 15581 141535 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 0.98 0.965 – 0.994 0.00669 19823 152331 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.01 0.931 – 1.09 0.836 690 6882 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.992 0.975 – 1.01 0.333 14932 129706 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.967 0.911 – 1.03 0.271 1190 11965 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 0.967 0.921 – 1.02 0.181 1778 17915 exclusion phecode
414.2 ASCVD Circulatory System 1.04 0.813 – 1.32 0.777 68 700 exclusion phecode
415 Pulmonary heart disease Circulatory System 0.987 0.956 – 1.02 0.402 4263 44171 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.29 1.02 – 1.63 0.0311 72 738 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.973 0.893 – 1.06 0.524 587 5884 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 0.965 0.876 – 1.06 0.47 440 4391 exclusion phecode
416 Cardiomegaly Circulatory System 0.999 0.96 – 1.04 0.972 2630 26331 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.01 0.997 – 1.02 0.16 28132 266847 exclusion phecode
418.1 Precordial pain Circulatory System 0.974 0.941 – 1.01 0.141 3495 35068 exclusion phecode
420 Carditis Circulatory System 1 0.956 – 1.05 0.985 2057 20727 exclusion phecode
420.1 Myocarditis Circulatory System 0.996 0.826 – 1.2 0.963 126 1247 exclusion phecode
420.2 Pericarditis Circulatory System 0.993 0.939 – 1.05 0.81 1313 13159 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.02 0.89 – 1.17 0.77 219 2198 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.05 0.863 – 1.27 0.645 113 1113 exclusion phecode
420.3 Endocarditis Circulatory System 1.03 0.951 – 1.11 0.473 694 7082 exclusion phecode
425 Cardiomyopathy Circulatory System 1 0.944 – 1.06 0.959 1243 12516 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.999 0.941 – 1.06 0.976 1210 12166 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.05 0.876 – 1.26 0.602 130 1303 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.953 0.812 – 1.12 0.558 159 1606 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.13 0.865 – 1.47 0.372 59 589 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.02 0.991 – 1.04 0.224 6739 68052 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 0.986 0.943 – 1.03 0.554 2070 20807 exclusion phecode
426.21 First degree AV block Circulatory System 1.01 0.94 – 1.07 0.884 964 9694 exclusion phecode
426.23 Second degree AV block Circulatory System 1.04 0.947 – 1.15 0.397 446 4446 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 0.915 0.841 – 0.996 0.0401 573 5761 exclusion phecode
426.25 Other heart block Circulatory System 0.939 0.787 – 1.12 0.482 130 1300 exclusion phecode
426.3 Bundle branch block Circulatory System 1.01 0.975 – 1.05 0.572 3239 32827 exclusion phecode
426.31 Right bundle branch block Circulatory System 0.973 0.921 – 1.03 0.322 1444 14690 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.03 0.981 – 1.08 0.23 1706 17229 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.03 0.903 – 1.18 0.63 231 2305 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 0.881 0.673 – 1.16 0.36 58 595 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.02 0.975 – 1.06 0.45 2416 24343 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.02 0.98 – 1.07 0.29 2219 22361 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1 0.989 – 1.02 0.669 23563 203366 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.02 0.984 – 1.06 0.273 3119 31597 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.04 0.992 – 1.08 0.109 2286 23175 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.01 0.943 – 1.08 0.781 913 9216 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1 0.983 – 1.02 0.962 14243 131478 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.993 0.957 – 1.03 0.702 3146 31803 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1 0.944 – 1.06 0.942 1160 11750 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.04 0.932 – 1.17 0.464 338 3387 exclusion phecode
427.42 Cardiac arrest Circulatory System 0.984 0.922 – 1.05 0.64 960 9749 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.967 0.905 – 1.03 0.327 927 9415 exclusion phecode
427.6 Premature beats Circulatory System 0.979 0.895 – 1.07 0.635 526 5300 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 0.992 0.823 – 1.2 0.93 115 1159 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.03 0.984 – 1.08 0.202 2047 21593 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.04 0.935 – 1.15 0.503 396 3962 exclusion phecode
427.9 Palpitations Circulatory System 1.01 0.978 – 1.05 0.505 3747 37672 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.968 0.942 – 0.996 0.0242 5474 54965 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 0.956 0.913 – 1 0.0515 2070 20723 exclusion phecode
428.2 Heart failure NOS Circulatory System 0.972 0.942 – 1 0.0771 4344 43666 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 0.927 0.858 – 1 0.0597 701 7065 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 0.959 0.738 – 1.25 0.753 63 626 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.908 0.829 – 0.995 0.0388 512 5132 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.01 0.871 – 1.18 0.873 191 1953 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.01 0.958 – 1.05 0.826 1856 18541 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.958 0.891 – 1.03 0.243 827 8261 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1 0.93 – 1.08 0.959 754 7537 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.09 0.958 – 1.23 0.197 261 2609 exclusion phecode
433 Cerebrovascular disease Circulatory System 0.984 0.962 – 1.01 0.158 8577 86031 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.998 0.94 – 1.06 0.959 1164 11598 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 0.982 0.857 – 1.13 0.795 222 2231 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.966 0.936 – 0.998 0.0368 4144 41619 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.939 0.893 – 0.988 0.016 1646 16518 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.03 0.99 – 1.07 0.146 2836 28514 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.02 0.98 – 1.07 0.285 2098 21027 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 0.99 0.893 – 1.1 0.85 392 3897 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.933 0.881 – 0.989 0.0192 1252 12593 exclusion phecode
440 Atherosclerosis Circulatory System 0.983 0.929 – 1.04 0.55 1358 13576 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.983 0.805 – 1.2 0.869 112 1116 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.02 0.947 – 1.1 0.607 795 7916 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 0.939 0.83 – 1.06 0.319 280 2816 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 0.954 0.875 – 1.04 0.283 566 6074 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.924 0.815 – 1.05 0.212 259 2787 exclusion phecode
442 Other aneurysm Circulatory System 0.981 0.935 – 1.03 0.441 1833 18614 exclusion phecode
442.1 Aortic aneurysm Circulatory System 0.991 0.938 – 1.05 0.737 1406 14344 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.977 0.911 – 1.05 0.51 892 9140 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 0.952 0.772 – 1.18 0.65 99 996 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.959 0.814 – 1.13 0.617 163 1664 exclusion phecode
442.4 Arterial dissection Circulatory System 1.1 0.836 – 1.45 0.499 53 544 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 0.949 0.819 – 1.1 0.482 201 2001 exclusion phecode
443 Peripheral vascular disease Circulatory System 0.981 0.949 – 1.01 0.266 3827 38674 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.08 1.02 – 1.15 0.0131 1128 11314 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.967 0.87 – 1.07 0.533 380 3806 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 0.982 0.949 – 1.02 0.308 3595 36351 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.953 0.915 – 0.993 0.021 2505 25399 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 0.938 0.875 – 1.01 0.0714 894 9097 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.918 0.839 – 1 0.0613 539 5445 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.02 0.952 – 1.1 0.54 803 8100 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 1.03 0.883 – 1.2 0.714 181 1837 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.04 0.936 – 1.15 0.479 382 3823 exclusion phecode
446.9 Arteritis NOS Circulatory System 0.996 0.872 – 1.14 0.948 234 2358 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 0.943 0.891 – 0.998 0.0427 1296 13101 exclusion phecode
447.1 Stricture of artery Circulatory System 0.92 0.857 – 0.987 0.0196 851 8556 exclusion phecode
448 Disease of capillaries Circulatory System 1.06 0.889 – 1.26 0.528 139 1403 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.03 0.954 – 1.12 0.422 676 6935 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1 0.971 – 1.04 0.798 3805 39199 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.999 0.965 – 1.03 0.973 3546 36531 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 0.906 0.829 – 0.99 0.0291 528 5581 exclusion phecode
454 Varicose veins Circulatory System 0.993 0.974 – 1.01 0.505 11047 110866 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 0.99 0.971 – 1.01 0.314 11368 114035 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.977 0.899 – 1.06 0.591 611 6262 exclusion phecode
455 Hemorrhoids Circulatory System 1.03 1.01 – 1.04 8.29e-05 22925 231944 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.965 0.828 – 1.13 0.654 182 1847 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.03 0.841 – 1.25 0.797 94 957 exclusion phecode
458 Hypotension Circulatory System 1.02 0.992 – 1.05 0.156 5484 56992 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.06 1 – 1.12 0.04 1280 13162 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.12 0.973 – 1.28 0.115 223 2310 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.02 0.988 – 1.06 0.186 3315 34555 exclusion phecode
459 Other disorders of circulatory system Circulatory System 0.991 0.975 – 1.01 0.289 15703 158666 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 0.905 0.756 – 1.08 0.275 137 1397 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 0.99 0.974 – 1.01 0.254 15546 157304 exclusion phecode
464 Acute sinusitis Respiratory 1.26 1.08 – 1.46 0.00272 193 1930 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.983 0.941 – 1.03 0.432 2228 22558 exclusion phecode
465.2 Acute pharyngitis Respiratory 0.989 0.921 – 1.06 0.769 816 8249 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.867 0.741 – 1.01 0.0758 163 1629 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.989 0.959 – 1.02 0.474 4608 46058 exclusion phecode
471 Nasal polyps Respiratory 1.01 0.975 – 1.05 0.566 3248 32503 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.977 0.915 – 1.04 0.492 950 9476 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 0.977 0.938 – 1.02 0.256 2507 25195 exclusion phecode
473.1 Chronic laryngitis Respiratory 0.967 0.795 – 1.18 0.738 104 1024 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.02 0.901 – 1.17 0.711 252 2603 exclusion phecode
473.4 Voice disturbance Respiratory 1 0.944 – 1.07 0.879 1063 10634 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 0.997 0.949 – 1.05 0.893 1755 17577 exclusion phecode
474.1 Acute tonsillitis Respiratory 0.972 0.89 – 1.06 0.533 543 5445 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.04 0.974 – 1.1 0.258 1111 11119 exclusion phecode
475 Chronic sinusitis Respiratory 1.01 0.969 – 1.05 0.643 2560 25567 exclusion phecode
476 Allergic rhinitis Respiratory 1.01 0.944 – 1.07 0.842 1035 10451 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 0.962 0.923 – 1 0.074 2401 24106 exclusion phecode
478 Throat pain Respiratory 0.897 0.806 – 0.998 0.0455 368 3747 exclusion phecode
479 Other upper respiratory disease Respiratory 0.996 0.964 – 1.03 0.793 4024 40246 exclusion phecode
480 Pneumonia Respiratory 1 0.983 – 1.02 0.758 9900 101933 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1 0.974 – 1.03 0.991 6348 65503 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 0.996 0.969 – 1.02 0.756 5630 58064 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.25 1.01 – 1.56 0.0395 90 912 exclusion phecode
480.2 Viral pneumonia Respiratory 0.987 0.782 – 1.25 0.912 71 712 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.957 0.774 – 1.18 0.681 92 981 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.02 0.947 – 1.1 0.61 759 7808 exclusion phecode
481 Influenza Respiratory 0.949 0.848 – 1.06 0.358 317 3237 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.934 0.803 – 1.09 0.378 191 1910 exclusion phecode
495 Asthma Respiratory 1.01 0.999 – 1.03 0.0617 25216 247690 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.07 0.932 – 1.22 0.354 248 2487 exclusion phecode
496 Chronic airway obstruction Respiratory 1.02 0.995 – 1.04 0.138 10146 100012 exclusion phecode
496.1 Emphysema Respiratory 1.04 0.99 – 1.09 0.121 1685 17157 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.05 1.01 – 1.09 0.0178 2871 29014 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.05 1.01 – 1.09 0.0149 2631 26633 exclusion phecode
496.3 Bronchiectasis Respiratory 1 0.957 – 1.05 0.872 1839 18579 exclusion phecode
497 Bronchitis Respiratory 0.922 0.849 – 1 0.0559 610 6190 exclusion phecode
500 Lung disease due to external agents Respiratory 0.921 0.832 – 1.02 0.112 400 4017 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.895 0.714 – 1.12 0.332 76 778 exclusion phecode
500.2 Pneumoconiosis Respiratory 0.937 0.823 – 1.07 0.327 236 2353 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.05 0.966 – 1.14 0.258 623 6463 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.989 0.923 – 1.06 0.758 886 9034 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 0.91 0.829 – 0.999 0.0477 486 5004 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.879 0.784 – 0.986 0.0277 318 3241 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 0.921 0.711 – 1.19 0.533 60 605 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.01 0.952 – 1.08 0.678 1077 11206 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.01 0.982 – 1.04 0.535 6078 63347 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.07 1.02 – 1.12 0.00723 1886 19671 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 0.993 0.953 – 1.04 0.751 2491 25638 exclusion phecode
509.1 Respiratory failure Respiratory 0.985 0.94 – 1.03 0.514 1982 20392 exclusion phecode
509.2 Respiratory insufficiency Respiratory 0.979 0.932 – 1.03 0.396 1734 17826 exclusion phecode
509.5 Respiratory arrest Respiratory 1.08 0.908 – 1.29 0.376 138 1414 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.02 0.919 – 1.14 0.664 374 3811 exclusion phecode
510 Other diseases of lung Respiratory 1.06 0.982 – 1.15 0.137 705 7457 exclusion phecode
512 Other symptoms of respiratory system Respiratory 0.985 0.964 – 1.01 0.185 8824 89103 exclusion phecode
512.1 Wheezing Respiratory 1.07 0.931 – 1.23 0.336 215 2168 exclusion phecode
512.2 Painful respiration Respiratory 1.05 0.912 – 1.21 0.491 203 2042 exclusion phecode
512.7 Shortness of breath Respiratory 0.989 0.962 – 1.02 0.412 5706 57691 exclusion phecode
512.8 Cough Respiratory 0.973 0.936 – 1.01 0.174 2817 28239 exclusion phecode
512.9 Other dyspnea Respiratory 0.978 0.913 – 1.05 0.525 889 8995 exclusion phecode
513 Respiratory abnormalities Respiratory 0.962 0.884 – 1.05 0.374 595 6019 exclusion phecode
513.3 Hypoventilation Respiratory 1.01 0.809 – 1.26 0.937 82 813 exclusion phecode
513.4 Hyperventilation Respiratory 0.985 0.87 – 1.12 0.814 276 2753 exclusion phecode
513.8 Disorders of diaphragm Respiratory 0.879 0.738 – 1.05 0.148 140 1508 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 0.983 0.942 – 1.03 0.417 2326 24281 exclusion phecode
516 Abnormal sputum Respiratory 1.01 0.964 – 1.06 0.709 2091 21013 exclusion phecode
516.1 Hemoptysis Respiratory 1 0.957 – 1.05 0.929 2033 20438 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.01 0.992 – 1.04 0.23 9045 92441 exclusion phecode
519.2 Respiratory complications Respiratory 0.973 0.866 – 1.09 0.651 302 3226 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.01 0.99 – 1.04 0.268 8559 87379 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.978 0.87 – 1.1 0.702 294 3009 exclusion phecode
520 Disorders of tooth development Digestive 1.01 0.965 – 1.06 0.648 2017 20195 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.1 0.815 – 1.48 0.539 53 525 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 1.02 0.973 – 1.06 0.484 2331 23348 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.01 0.97 – 1.05 0.73 2977 29928 exclusion phecode
521.1 Dental caries Digestive 1.01 0.974 – 1.05 0.557 2988 30032 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.03 0.979 – 1.08 0.268 1755 17558 exclusion phecode
522.5 Periapical abscess Digestive 1.02 0.963 – 1.09 0.468 1160 11617 exclusion phecode
523 Gingival and periodontal diseases Digestive 1 0.953 – 1.05 0.925 1665 16644 exclusion phecode
523.1 Gingivitis Digestive 0.955 0.783 – 1.16 0.65 111 1111 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 0.959 0.903 – 1.02 0.174 1154 11536 exclusion phecode
523.31 Acute periodontitis Digestive 0.933 0.862 – 1.01 0.0881 659 6609 exclusion phecode
523.32 Chronic periodontitis Digestive 0.998 0.913 – 1.09 0.958 555 5539 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.994 0.886 – 1.12 0.923 327 3284 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1 0.893 – 1.13 0.936 301 3027 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.04 1 – 1.09 0.0393 2627 26394 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.2 0.956 – 1.51 0.117 72 707 exclusion phecode
526 Diseases of the jaws Digestive 0.998 0.933 – 1.07 0.954 917 9178 exclusion phecode
526.1 Cysts of the jaws Digestive 0.969 0.863 – 1.09 0.589 325 3244 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.08 0.826 – 1.4 0.584 61 604 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 0.871 0.762 – 0.997 0.0449 237 2384 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.86 0.75 – 0.986 0.0306 230 2316 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 1.08 0.893 – 1.31 0.425 109 1086 exclusion phecode
526.9 Jaw disease NOS Digestive 1.04 0.911 – 1.19 0.558 228 2305 exclusion phecode
527 Diseases of the salivary glands Digestive 0.975 0.902 – 1.05 0.531 685 6854 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.05 0.841 – 1.3 0.678 84 829 exclusion phecode
527.2 Sialoadenitis Digestive 0.93 0.835 – 1.04 0.185 360 3614 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.08 0.834 – 1.41 0.552 60 613 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.06 0.875 – 1.28 0.559 119 1181 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.998 0.965 – 1.03 0.904 3815 38269 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.06 0.958 – 1.16 0.275 452 4598 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.08 0.973 – 1.21 0.142 375 3826 exclusion phecode
528.12 Oral aphthae Digestive 0.94 0.748 – 1.18 0.599 82 826 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.02 0.874 – 1.18 0.831 175 1763 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.918 0.759 – 1.11 0.375 122 1206 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.864 0.696 – 1.07 0.185 94 927 exclusion phecode
528.5 Diseases of lips Digestive 1.01 0.93 – 1.09 0.872 674 6744 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 0.934 0.831 – 1.05 0.252 308 3049 exclusion phecode
528.7 Sialolithiasis Digestive 0.971 0.864 – 1.09 0.621 309 3094 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1 0.947 – 1.07 0.892 1209 12167 exclusion phecode
529.1 Glossitis Digestive 0.968 0.861 – 1.09 0.595 293 2963 exclusion phecode
530 Diseases of esophagus Digestive 1.01 0.995 – 1.02 0.307 32829 275989 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.01 0.996 – 1.02 0.205 30680 269276 exclusion phecode
530.11 GERD Digestive 1 0.988 – 1.02 0.779 22232 223173 exclusion phecode
530.12 Ulcer of esophagus Digestive 1 0.976 – 1.03 0.737 5076 51330 exclusion phecode
530.14 Reflux esophagitis Digestive 0.986 0.966 – 1.01 0.175 10258 103199 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.994 0.944 – 1.05 0.805 1629 16602 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 0.97 0.925 – 1.02 0.219 1831 18424 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.02 0.942 – 1.11 0.583 623 6294 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.11 0.935 – 1.31 0.238 147 1509 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.98 0.876 – 1.1 0.72 339 3378 exclusion phecode
530.9 Heartburn Digestive 0.996 0.952 – 1.04 0.849 2057 20642 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.991 0.967 – 1.02 0.482 6934 70045 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.973 0.895 – 1.06 0.522 610 6264 exclusion phecode
531.2 Gastric ulcer Digestive 0.971 0.94 – 1 0.0793 4008 40365 exclusion phecode
531.3 Duodenal ulcer Digestive 1.01 0.971 – 1.05 0.675 2929 29575 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 0.942 0.853 – 1.04 0.242 416 4203 exclusion phecode
532 Dysphagia Digestive 0.993 0.967 – 1.02 0.571 6302 63519 exclusion phecode
535 Gastritis and duodenitis Digestive 1.01 0.996 – 1.02 0.177 27552 258400 exclusion phecode
535.1 Acute gastritis Digestive 0.956 0.899 – 1.02 0.145 1159 11667 exclusion phecode
535.2 Atrophic gastritis Digestive 0.945 0.848 – 1.05 0.311 358 3637 exclusion phecode
535.6 Duodenitis Digestive 1.01 0.986 – 1.03 0.421 7441 74913 exclusion phecode
535.8 Other specified gastritis Digestive 0.999 0.976 – 1.02 0.916 7935 79709 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.11 0.918 – 1.34 0.283 114 1173 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.04 0.919 – 1.18 0.515 254 2537 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.02 0.983 – 1.06 0.3 3301 33439 exclusion phecode
540 Appendiceal conditions Digestive 1.01 0.968 – 1.04 0.787 3003 30581 exclusion phecode
540.1 Appendicitis Digestive 0.999 0.961 – 1.04 0.964 2824 28679 exclusion phecode
540.11 Acute appendicitis Digestive 0.997 0.957 – 1.04 0.886 2544 25750 exclusion phecode
550 Abdominal hernia Digestive 1.01 0.996 – 1.02 0.274 44364 279747 exclusion phecode
550.1 Inguinal hernia Digestive 1.01 0.994 – 1.03 0.212 15486 121638 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1 0.991 – 1.02 0.555 26025 236244 exclusion phecode
550.3 Femoral hernia Digestive 0.995 0.917 – 1.08 0.906 642 6427 exclusion phecode
550.4 Umbilical hernia Digestive 0.981 0.948 – 1.01 0.26 3642 36636 exclusion phecode
550.5 Ventral hernia Digestive 1.02 0.979 – 1.05 0.396 3074 33888 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.01 0.982 – 1.04 0.414 4324 44174 exclusion phecode
555.1 Regional enteritis Digestive 1 0.955 – 1.05 0.902 1689 17226 exclusion phecode
555.2 Ulcerative colitis Digestive 1.03 0.992 – 1.07 0.131 3087 31598 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.04 0.953 – 1.14 0.371 520 5349 exclusion phecode
556 Ulceration of the lower GI tract Digestive 0.989 0.926 – 1.06 0.752 963 10534 exclusion phecode
556.1 Ulceration of intestine Digestive 1.01 0.935 – 1.1 0.726 615 6674 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.03 0.913 – 1.16 0.632 294 2973 exclusion phecode
557.1 Celiac disease Digestive 1.03 0.981 – 1.08 0.239 1810 18272 exclusion phecode
558 Noninfectious gastroenteritis Digestive 0.996 0.979 – 1.01 0.653 14923 154228 exclusion phecode
559 Ileostomy status Digestive 1 0.94 – 1.07 0.892 913 16427 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.01 0.97 – 1.04 0.78 3313 39081 exclusion phecode
560.1 Paralytic ileus Digestive 0.938 0.844 – 1.04 0.228 377 5192 exclusion phecode
560.2 Impaction of intestine Digestive 1.02 0.893 – 1.15 0.819 252 2651 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.05 0.977 – 1.14 0.175 721 8264 exclusion phecode
560.4 Other intestinal obstruction Digestive 1.02 0.978 – 1.06 0.403 2860 33333 exclusion phecode
561 Symptoms involving digestive system Digestive 0.982 0.966 – 0.998 0.0295 15395 156810 exclusion phecode
561.1 Diarrhea Digestive 0.996 0.903 – 1.1 0.929 447 4625 exclusion phecode
561.2 Flatulence Digestive 0.987 0.938 – 1.04 0.611 1637 16770 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1.05 1.04 – 1.07 3.63e-15 25648 210391 exclusion phecode
562.1 Diverticulosis Digestive 1.05 1.04 – 1.07 3.33e-15 25609 210339 exclusion phecode
563 Constipation Digestive 0.991 0.971 – 1.01 0.412 9907 102533 exclusion phecode
564 Functional digestive disorders Digestive 1.07 1.05 – 1.08 1.27e-19 20898 208716 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.03 0.997 – 1.05 0.0806 5432 54839 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.08 1.03 – 1.14 0.00274 1525 16352 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.09 1.07 – 1.1 2.69e-21 14612 150651 exclusion phecode
565 Anal and rectal conditions Digestive 1.11 1.09 – 1.13 2.94e-31 13854 146150 exclusion phecode
565.1 Anal and rectal polyp Digestive 1.22 1.19 – 1.25 1.45e-53 6762 72770 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 0.948 0.881 – 1.02 0.154 784 9200 exclusion phecode
568 Other disorders of peritoneum Digestive 1.03 0.992 – 1.07 0.12 2875 32322 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.03 0.991 – 1.07 0.13 2732 30729 exclusion phecode
569 Other disorders of intestine Digestive 1.07 1.03 – 1.1 0.000134 3692 41516 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.02 0.844 – 1.23 0.835 108 1467 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.14 1.03 – 1.27 0.0142 353 4818 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.01 0.974 – 1.05 0.529 2870 29240 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 0.999 0.949 – 1.05 0.958 1642 16721 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.939 0.77 – 1.15 0.535 110 1125 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.03 0.909 – 1.17 0.627 251 2528 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.02 0.958 – 1.09 0.485 938 9648 exclusion phecode
571.81 Portal hypertension Digestive 1.07 0.977 – 1.17 0.143 508 5201 exclusion phecode
572 Ascites (non malignant) Digestive 0.99 0.937 – 1.05 0.73 1385 15256 exclusion phecode
573 Other disorders of liver Digestive 1.03 0.972 – 1.09 0.328 1361 14812 exclusion phecode
573.2 Liver replaced by transplant Digestive 0.933 0.75 – 1.16 0.536 90 947 exclusion phecode
573.3 Hepatomegaly Digestive 1.08 0.955 – 1.22 0.225 285 2937 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1 0.932 – 1.07 0.994 850 8833 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 0.986 0.951 – 1.02 0.427 3344 34151 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 0.924 0.798 – 1.07 0.291 199 2055 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.01 0.992 – 1.03 0.286 15306 154286 exclusion phecode
574.1 Cholelithiasis Digestive 1.01 0.99 – 1.03 0.369 13315 133967 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.984 0.933 – 1.04 0.559 1478 14854 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1 0.972 – 1.03 0.99 5359 53694 exclusion phecode
574.2 Calculus of bile duct Digestive 1.02 0.981 – 1.06 0.308 2570 25876 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.989 0.951 – 1.03 0.59 2671 27201 exclusion phecode
575 Other biliary tract disease Digestive 1.03 1 – 1.07 0.0466 3734 38242 exclusion phecode
575.1 Cholangitis Digestive 1.02 0.924 – 1.12 0.756 474 4864 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.04 0.959 – 1.12 0.376 726 7655 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 1.07 0.967 – 1.17 0.198 447 4536 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.01 0.952 – 1.06 0.837 1387 13930 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.06 0.991 – 1.13 0.0892 1007 10226 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.09 0.976 – 1.22 0.123 316 3442 exclusion phecode
577 Diseases of pancreas Digestive 0.974 0.935 – 1.01 0.193 2599 26309 exclusion phecode
577.1 Acute pancreatitis Digestive 0.965 0.922 – 1.01 0.134 1950 19701 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.01 0.925 – 1.11 0.792 502 5085 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.03 0.923 – 1.14 0.618 354 3611 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.999 – 1.03 0.0644 19938 203995 exclusion phecode
578.1 Hematemesis Digestive 1.03 0.98 – 1.08 0.26 1894 19350 exclusion phecode
578.2 Blood in stool Digestive 1 0.963 – 1.04 0.91 2536 25928 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.02 1 – 1.04 0.0543 12674 129330 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.01 0.984 – 1.04 0.392 5049 52208 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.02 0.967 – 1.08 0.466 1469 15349 exclusion phecode
579.2 Splenomegaly Digestive 0.987 0.893 – 1.09 0.794 411 4196 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.03 0.974 – 1.08 0.344 1599 16338 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.03 0.976 – 1.09 0.291 1493 15112 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.03 0.962 – 1.09 0.443 1022 10388 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.07 0.826 – 1.38 0.618 70 727 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.22 1.02 – 1.46 0.0321 132 1345 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1 0.932 – 1.07 0.994 852 8631 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.998 0.906 – 1.1 0.97 462 4624 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.14 0.997 – 1.3 0.0556 239 2426 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.14 0.997 – 1.3 0.0547 246 2496 exclusion phecode
585 Renal failure Genitourinary 0.994 0.969 – 1.02 0.643 6598 68704 exclusion phecode
585.1 Acute renal failure Genitourinary 0.997 0.967 – 1.03 0.875 4236 44633 exclusion phecode
585.2 Renal failure NOS Genitourinary 0.96 0.909 – 1.01 0.147 1385 14399 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.02 0.982 – 1.07 0.284 2551 26084 exclusion phecode
585.31 Renal dialysis Genitourinary 1.07 0.974 – 1.17 0.16 482 4898 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.02 0.98 – 1.05 0.383 3227 33135 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.04 0.899 – 1.2 0.601 197 2063 exclusion phecode
586.11 Small kidney Genitourinary 1.09 0.93 – 1.27 0.297 170 1776 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.06 0.999 – 1.13 0.0526 1211 12394 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.14 0.9 – 1.44 0.279 79 792 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.973 0.907 – 1.04 0.447 863 9005 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.08 0.968 – 1.21 0.168 357 3648 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.19 0.957 – 1.47 0.119 96 980 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.08 0.889 – 1.32 0.428 110 1143 exclusion phecode
590 Pyelonephritis Genitourinary 1.02 0.964 – 1.08 0.468 1290 13162 exclusion phecode
591 Urinary tract infection Genitourinary 1.02 0.997 – 1.04 0.104 11914 122436 exclusion phecode
592 Cystitis and urethritis Genitourinary 0.989 0.952 – 1.03 0.553 2915 29299 exclusion phecode
592.1 Cystitis Genitourinary 1 0.962 – 1.04 0.996 2854 28676 exclusion phecode
592.11 Acute cystitis Genitourinary 0.933 0.784 – 1.11 0.438 136 1356 exclusion phecode
592.12 Chronic cystitis Genitourinary 0.955 0.89 – 1.02 0.193 873 8784 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 0.991 0.868 – 1.13 0.896 245 2470 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.878 0.747 – 1.03 0.114 164 1645 exclusion phecode
593 Hematuria Genitourinary 1.01 0.989 – 1.02 0.486 15757 158136 exclusion phecode
594 Urinary calculus Genitourinary 1.01 0.98 – 1.03 0.636 6257 62925 exclusion phecode
594.1 Calculus of kidney Genitourinary 0.969 0.934 – 1.01 0.0971 3112 31333 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.02 0.944 – 1.1 0.64 753 7623 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.03 0.984 – 1.07 0.231 2357 23704 exclusion phecode
594.8 Renal colic Genitourinary 1.04 0.996 – 1.09 0.0726 2014 20253 exclusion phecode
595 Hydronephrosis Genitourinary 1.01 0.958 – 1.06 0.818 1815 19144 exclusion phecode
596 Other disorders of bladder Genitourinary 1 0.983 – 1.02 0.746 9577 96353 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 0.987 0.942 – 1.03 0.576 1931 19350 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1.02 0.972 – 1.08 0.387 1633 16378 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.988 0.955 – 1.02 0.462 3841 38603 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.98 0.945 – 1.02 0.273 3263 32691 exclusion phecode
597.2 Urinary complications NEC Genitourinary 0.877 0.688 – 1.12 0.292 72 767 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 0.993 0.959 – 1.03 0.698 3450 34802 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.907 0.804 – 1.02 0.115 287 2993 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.991 – 1.02 0.399 18072 182051 exclusion phecode
599.1 Urinary obstruction Genitourinary 1.14 0.965 – 1.34 0.124 161 1646 exclusion phecode
599.2 Retention of urine Genitourinary 0.998 0.973 – 1.02 0.874 6452 66055 exclusion phecode
599.3 Dysuria Genitourinary 0.983 0.925 – 1.04 0.568 1164 11820 exclusion phecode
599.4 Urinary incontinence Genitourinary 1.01 0.988 – 1.03 0.392 8641 86579 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.01 0.98 – 1.05 0.458 3941 39633 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.07 0.878 – 1.31 0.495 102 1042 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 0.881 0.677 – 1.15 0.349 61 610 exclusion phecode
599.9 Other abnormality of urination Genitourinary 1.03 0.987 – 1.08 0.158 1873 18872 exclusion phecode
600 Hyperplasia of prostate Genitourinary 1 0.981 – 1.02 0.893 10800 86359 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 1 0.957 – 1.05 0.961 2041 20490 exclusion phecode
601.1 Prostatitis Genitourinary 0.999 0.949 – 1.05 0.985 1534 15383 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.997 0.872 – 1.14 0.965 230 2325 exclusion phecode
601.12 Chronic prostatitis Genitourinary 0.962 0.899 – 1.03 0.266 894 8943 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 1 0.771 – 1.3 0.986 58 580 exclusion phecode
601.4 Balanoposthitis Genitourinary 0.956 0.847 – 1.08 0.471 281 2815 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.02 0.905 – 1.15 0.757 296 2973 exclusion phecode
602 Other disorders of prostate Genitourinary 0.949 0.897 – 1 0.0676 1313 13172 exclusion phecode
603 Other disorders of testis Genitourinary 0.999 0.955 – 1.04 0.959 2102 21212 exclusion phecode
603.1 Hydrocele Genitourinary 1.01 0.957 – 1.07 0.65 1308 13220 exclusion phecode
604 Disorders of penis Genitourinary 0.975 0.941 – 1.01 0.179 3217 32377 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.982 0.944 – 1.02 0.374 2672 26853 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 0.996 0.88 – 1.13 0.954 267 2746 exclusion phecode
608 Other disorders of male genital organs Genitourinary 1.02 0.976 – 1.06 0.446 2760 27813 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.05 0.911 – 1.2 0.528 211 2116 exclusion phecode
609.1 Infertility, male Genitourinary 0.9 0.699 – 1.16 0.414 62 632 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 1.08 0.926 – 1.26 0.324 166 1677 exclusion phecode
610 Benign mammary dysplasias Genitourinary 1.03 0.989 – 1.07 0.152 2460 24605 exclusion phecode
610.1 Cystic mastopathy Genitourinary 1.02 0.957 – 1.1 0.489 916 9163 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1.19 1.06 – 1.35 0.00336 302 3033 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 1.01 0.9 – 1.14 0.825 300 2985 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 1.03 0.971 – 1.08 0.361 1377 13751 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1 0.927 – 1.08 0.948 685 6890 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.04 0.99 – 1.1 0.11 1555 15580 exclusion phecode
611.1 Abnormal mammogram Genitourinary 0.928 0.71 – 1.21 0.582 56 567 exclusion phecode
611.3 Lump or mass in breast Genitourinary 1.04 0.991 – 1.1 0.107 1504 15061 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.05 0.978 – 1.12 0.18 877 8797 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.04 0.97 – 1.12 0.268 839 8412 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 1.03 0.812 – 1.3 0.825 71 715 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 1.09 1.04 – 1.15 0.000857 1634 16376 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.1 1.02 – 1.18 0.0169 713 7150 exclusion phecode
613.5 Mastodynia Genitourinary 1.06 0.852 – 1.33 0.582 75 761 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 1.04 0.96 – 1.12 0.357 693 6950 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1.05 0.936 – 1.17 0.416 326 3250 exclusion phecode
613.9 Breast disorder NOS Genitourinary 1.05 0.908 – 1.21 0.523 203 2049 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.996 0.969 – 1.02 0.768 5620 56700 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1 0.963 – 1.05 0.879 2500 25172 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1 0.933 – 1.08 0.923 808 8254 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.844 0.644 – 1.1 0.217 57 607 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.949 0.857 – 1.05 0.312 415 4189 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.07 0.952 – 1.2 0.261 342 3488 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.939 0.83 – 1.06 0.321 274 2764 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.976 0.937 – 1.02 0.236 2569 25813 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.986 0.931 – 1.04 0.616 1307 13081 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.936 0.847 – 1.03 0.196 417 4234 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.03 0.959 – 1.12 0.385 750 7522 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.935 0.826 – 1.06 0.281 270 2711 exclusion phecode
615 Endometriosis Genitourinary 1.01 0.982 – 1.05 0.376 3993 40014 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.03 0.909 – 1.16 0.653 285 3017 exclusion phecode
618 Genital prolapse Genitourinary 1.01 0.989 – 1.03 0.387 11570 115631 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 1.02 0.994 – 1.04 0.139 7318 73151 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1 0.974 – 1.03 0.925 5344 53340 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.975 0.891 – 1.07 0.586 510 5068 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.998 0.922 – 1.08 0.955 675 6717 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 0.998 0.976 – 1.02 0.875 8617 86611 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.893 0.828 – 0.963 0.00348 720 7235 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 0.998 0.963 – 1.03 0.918 3285 32994 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.02 0.982 – 1.06 0.291 2822 28388 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.988 0.94 – 1.04 0.627 1740 17520 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.03 0.976 – 1.09 0.269 1334 13371 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1.15 0.899 – 1.46 0.268 69 715 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.943 0.887 – 1 0.0581 1113 11188 exclusion phecode
622 Polyp of female genital organs Genitourinary 1.01 0.989 – 1.03 0.394 10359 103874 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 1 0.981 – 1.03 0.734 7766 77894 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 1.01 0.974 – 1.05 0.613 3405 34052 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.05 0.987 – 1.11 0.127 1255 12603 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.967 0.899 – 1.04 0.364 783 7884 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.969 0.848 – 1.11 0.64 235 2336 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 0.967 0.876 – 1.07 0.497 430 4352 exclusion phecode
624.9 stress incontinence, female Genitourinary 1.01 0.983 – 1.04 0.492 5813 58090 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1 0.962 – 1.04 0.988 2850 28526 exclusion phecode
625.1 Dyspareunia Genitourinary 1.03 0.972 – 1.1 0.302 1178 11804 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1 0.988 – 1.02 0.559 16067 114249 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.01 0.987 – 1.02 0.576 14025 109196 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 1 0.825 – 1.22 0.984 108 1094 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 1 0.98 – 1.02 0.92 9655 91177 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 1.02 0.971 – 1.06 0.485 1966 19671 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 1 0.967 – 1.03 0.987 3773 37812 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.994 0.947 – 1.04 0.818 1774 17660 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.932 0.792 – 1.1 0.392 158 1582 exclusion phecode
626.8 Infertility, female Genitourinary 0.969 0.916 – 1.02 0.264 1353 13576 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 1 0.984 – 1.02 0.678 10248 102855 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 1.01 0.985 – 1.03 0.537 8914 89478 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.978 0.84 – 1.14 0.779 181 1815 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.02 0.962 – 1.09 0.461 1091 10983 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 0.926 0.824 – 1.04 0.202 310 3071 exclusion phecode
628 Ovarian cyst Genitourinary 0.996 0.967 – 1.03 0.813 4679 47134 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.982 0.953 – 1.01 0.221 5200 36305 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.968 0.911 – 1.03 0.297 1131 11273 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.851 0.76 – 0.953 0.0053 329 3297 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.975 0.931 – 1.02 0.295 1969 17328 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.951 0.887 – 1.02 0.159 863 8594 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.01 0.954 – 1.07 0.712 1267 12279 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.976 0.935 – 1.02 0.257 2342 19915 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.98 0.903 – 1.06 0.619 617 6126 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.95 0.892 – 1.01 0.107 1076 10737 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 0.98 0.771 – 1.24 0.868 70 700 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.993 0.933 – 1.06 0.825 1108 11044 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.973 0.865 – 1.1 0.653 306 3052 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.08 0.938 – 1.24 0.291 215 2143 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.09 0.923 – 1.29 0.304 153 1521 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.988 0.933 – 1.05 0.687 1249 12420 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1 0.962 – 1.05 0.836 2224 20804 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.15 0.902 – 1.48 0.255 68 671 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.923 0.815 – 1.04 0.201 274 2742 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.954 0.788 – 1.16 0.63 113 1126 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.97 0.838 – 1.12 0.685 192 1915 exclusion phecode
650 Normal delivery Pregnancy Complications 1.06 1.01 – 1.11 0.0228 1918 18921 exclusion phecode
651 Multiple gestation Pregnancy Complications 0.966 0.864 – 1.08 0.544 345 3446 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.986 0.939 – 1.04 0.588 1712 16486 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.978 0.925 – 1.03 0.42 1398 13618 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.03 0.816 – 1.31 0.787 74 737 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.01 0.975 – 1.04 0.669 4294 29367 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.999 0.817 – 1.22 0.99 108 1077 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 1.01 0.967 – 1.06 0.656 2261 18340 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 1.06 0.973 – 1.16 0.176 531 5301 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 1.02 0.993 – 1.05 0.137 5298 29388 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.04 0.998 – 1.08 0.0595 2547 21115 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.21 1.04 – 1.42 0.0163 164 1627 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.931 0.823 – 1.05 0.258 262 2599 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.04 0.812 – 1.33 0.759 63 621 exclusion phecode
679 Complications of in utero procedures Dermatologic 0.942 0.709 – 1.25 0.677 53 528 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.01 0.985 – 1.03 0.463 7028 71238 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.95 0.87 – 1.04 0.252 547 5570 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.979 0.895 – 1.07 0.639 511 5140 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.02 0.99 – 1.05 0.207 5391 54266 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.02 0.99 – 1.05 0.203 5397 54319 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.02 0.99 – 1.05 0.208 5355 53891 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.01 0.929 – 1.11 0.749 545 5904 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.01 0.95 – 1.07 0.832 1305 13250 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.03 0.983 – 1.07 0.237 2242 22690 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.06 0.975 – 1.16 0.17 569 5791 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 1.04 0.937 – 1.16 0.439 360 3567 exclusion phecode
687 Symptoms affecting skin Dermatologic 1.01 0.928 – 1.11 0.762 531 5436 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.986 0.942 – 1.03 0.531 2068 21185 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 0.98 0.867 – 1.11 0.745 277 2798 exclusion phecode
687.3 Changes in skin texture Dermatologic 1.29 1.06 – 1.57 0.0123 99 1055 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1.01 0.971 – 1.05 0.635 2835 28526 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.01 0.981 – 1.04 0.556 5632 56799 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 1.01 0.777 – 1.3 0.965 69 699 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.859 0.636 – 1.16 0.324 52 520 exclusion phecode
691 Congenital anomalies of skin Dermatologic 1.16 0.966 – 1.39 0.113 119 1189 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 1.03 0.965 – 1.1 0.374 968 9751 exclusion phecode
694.1 Vitiligo Dermatologic 1.62 1.24 – 2.13 0.000451 60 594 exclusion phecode
694.2 Other dyschromia Dermatologic 1.01 0.938 – 1.09 0.81 769 7735 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 0.896 0.739 – 1.09 0.266 112 1159 exclusion phecode
695 Erythematous conditions Dermatologic 1.02 0.979 – 1.07 0.315 2309 23552 exclusion phecode
695.1 Toxic erythema Dermatologic 0.947 0.779 – 1.15 0.581 106 1081 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.1 0.923 – 1.32 0.278 134 1352 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 1.05 0.795 – 1.39 0.725 56 564 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.09 0.855 – 1.38 0.501 72 717 exclusion phecode
695.3 Rosacea Dermatologic 1.01 0.896 – 1.14 0.884 305 3056 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.07 0.971 – 1.19 0.167 401 4071 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.06 0.877 – 1.28 0.552 124 1279 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.07 0.956 – 1.19 0.246 335 3374 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 1.06 0.981 – 1.14 0.141 759 7673 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 0.917 0.8 – 1.05 0.217 227 2339 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.973 0.775 – 1.22 0.812 73 750 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.03 0.931 – 1.13 0.595 437 4615 exclusion phecode
696 Psoriasis and related disorders Dermatologic 1.01 0.97 – 1.06 0.551 2205 22243 exclusion phecode
696.4 Psoriasis Dermatologic 1.02 0.972 – 1.06 0.488 2155 21721 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 1 0.953 – 1.05 0.921 1642 16585 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 1.04 0.964 – 1.12 0.302 696 6990 exclusion phecode
697 Sarcoidosis Dermatologic 1.05 0.963 – 1.15 0.262 524 5326 exclusion phecode
698 Pruritus and related conditions Dermatologic 0.968 0.898 – 1.04 0.399 758 7729 exclusion phecode
700 Corns and callosities Dermatologic 1.08 0.956 – 1.22 0.22 289 2875 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.01 0.981 – 1.04 0.462 4569 46130 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.973 0.774 – 1.22 0.816 82 856 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.998 0.956 – 1.04 0.922 2310 23217 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 1.17 0.895 – 1.52 0.255 60 602 exclusion phecode
701.4 Keloid scar Dermatologic 1.1 0.958 – 1.26 0.18 212 2137 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 1.05 0.953 – 1.16 0.315 437 4522 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.1 0.901 – 1.35 0.348 100 1006 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.02 0.989 – 1.05 0.233 5359 53813 exclusion phecode
702.1 Actinic keratosis Dermatologic 1.01 0.971 – 1.05 0.59 2535 25442 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 1.01 0.975 – 1.05 0.515 3022 30362 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.04 0.934 – 1.16 0.458 348 3500 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.919 0.86 – 0.981 0.0118 954 9559 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 1.03 1 – 1.06 0.048 5191 52113 exclusion phecode
704.1 Alopecia Dermatologic 1.12 0.931 – 1.34 0.235 122 1255 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.924 0.725 – 1.18 0.525 75 753 exclusion phecode
705 Disorders of sweat glands Dermatologic 1.16 1.01 – 1.33 0.0307 223 2268 exclusion phecode
705.3 Hidradenitis Dermatologic 1.17 1 – 1.36 0.0447 181 1853 exclusion phecode
705.8 Hyperhidrosis Dermatologic 0.993 0.911 – 1.08 0.864 577 5853 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1.03 1.01 – 1.05 0.0117 8188 82234 exclusion phecode
706.1 Acne Dermatologic 1.17 0.928 – 1.47 0.187 76 772 exclusion phecode
706.2 Sebaceous cyst Dermatologic 1.03 1.01 – 1.05 0.0155 8655 86856 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1 0.956 – 1.05 0.928 1869 19368 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.02 0.955 – 1.1 0.491 845 8962 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 1.02 0.986 – 1.06 0.244 3376 33883 exclusion phecode
709.2 Sicca syndrome Dermatologic 0.952 0.868 – 1.04 0.3 497 5017 exclusion phecode
709.3 Systemic sclerosis Dermatologic 1.31 1.12 – 1.53 0.000742 175 1731 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.2 0.929 – 1.56 0.161 64 645 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.03 0.986 – 1.07 0.2 2673 26799 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.06 0.973 – 1.15 0.184 593 5938 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.08 0.986 – 1.17 0.1 548 5492 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.06 0.918 – 1.23 0.408 193 1909 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.07 0.966 – 1.19 0.194 392 3932 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 0.98 0.887 – 1.08 0.699 419 4173 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 0.96 0.858 – 1.07 0.479 326 3262 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.16 0.929 – 1.45 0.191 76 796 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.05 0.897 – 1.23 0.537 148 1480 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.09 0.86 – 1.39 0.466 65 658 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.01 0.983 – 1.04 0.403 4752 47696 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.02 0.984 – 1.05 0.331 4303 43154 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.05 1 – 1.11 0.0437 1634 16375 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.08 0.896 – 1.3 0.418 113 1118 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.08 0.994 – 1.17 0.0712 608 6106 exclusion phecode
716 Other arthropathies Musculoskeletal 1.01 1 – 1.02 0.0295 36833 262243 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1 0.967 – 1.04 0.95 3446 34605 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.02 1 – 1.04 0.0112 15293 153263 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.01 1 – 1.02 0.035 35320 259193 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.988 0.93 – 1.05 0.707 1116 11297 exclusion phecode
720 Spinal stenosis Musculoskeletal 0.983 0.95 – 1.02 0.322 3662 36496 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1 0.98 – 1.03 0.812 7690 77272 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.982 0.954 – 1.01 0.233 4966 49803 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.04 0.895 – 1.21 0.615 188 1868 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 1.18 1.06 – 1.32 0.00337 345 3476 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1 0.978 – 1.02 0.967 8876 88827 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.984 0.899 – 1.08 0.724 506 5043 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1 0.965 – 1.04 0.876 2795 27991 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.17 0.906 – 1.52 0.227 66 665 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.997 0.966 – 1.03 0.833 4358 43627 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 0.999 0.912 – 1.09 0.974 511 5113 exclusion phecode
723.1 Torticollis Musculoskeletal 1.09 0.897 – 1.33 0.377 106 1055 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1 0.959 – 1.05 0.861 2028 20257 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 1.06 0.958 – 1.18 0.255 398 3978 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 1.07 0.969 – 1.19 0.175 401 4010 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.03 0.791 – 1.34 0.826 61 629 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 0.988 0.939 – 1.04 0.65 1597 15937 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1 0.987 – 1.02 0.636 14505 144899 exclusion phecode
726.1 Enthesopathy Musculoskeletal 1 0.98 – 1.02 0.939 9481 94699 exclusion phecode
726.2 Synoviopathy Musculoskeletal 1.03 0.919 – 1.15 0.632 331 3308 exclusion phecode
726.3 Bursitis Musculoskeletal 0.936 0.873 – 1 0.0665 844 8468 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.01 0.983 – 1.03 0.581 7250 72448 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.01 0.967 – 1.05 0.748 2708 27072 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.887 0.727 – 1.08 0.239 101 1017 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.03 0.99 – 1.07 0.158 3072 30728 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.984 0.903 – 1.07 0.713 579 5778 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.982 0.879 – 1.1 0.743 348 3475 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.986 0.831 – 1.17 0.873 142 1410 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.976 0.943 – 1.01 0.159 3611 36163 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.07 0.964 – 1.18 0.208 408 4082 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.984 0.952 – 1.02 0.358 3736 37425 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.982 0.948 – 1.02 0.296 3413 34202 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1 0.977 – 1.03 0.803 5892 59569 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.958 0.898 – 1.02 0.201 1000 9973 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.932 0.759 – 1.14 0.502 100 999 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.998 0.883 – 1.13 0.975 272 2725 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.993 0.875 – 1.13 0.914 257 2579 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.987 0.898 – 1.08 0.78 463 4636 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.891 0.772 – 1.03 0.113 206 2042 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.946 0.725 – 1.23 0.68 57 562 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.02 0.97 – 1.07 0.465 1748 17617 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.04 0.922 – 1.17 0.55 303 3086 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.944 0.863 – 1.03 0.204 528 5331 exclusion phecode
733.6 Costochondritis Musculoskeletal 0.944 0.792 – 1.13 0.524 124 1261 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.963 0.908 – 1.02 0.218 1221 12172 exclusion phecode
733.9 Chondromalacia Musculoskeletal 0.926 0.77 – 1.11 0.417 121 1193 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1 0.983 – 1.03 0.686 9494 94976 exclusion phecode
735.1 Flat foot Musculoskeletal 0.936 0.804 – 1.09 0.392 187 1885 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 1.01 0.982 – 1.04 0.448 5005 50094 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.993 0.947 – 1.04 0.782 1899 19068 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.995 0.944 – 1.05 0.866 1531 15331 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.02 0.99 – 1.04 0.221 6572 65712 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 1.01 0.956 – 1.06 0.798 1605 16071 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.1 0.966 – 1.26 0.146 244 2446 exclusion phecode
737 Curvature of spine Musculoskeletal 1.07 1 – 1.14 0.0358 1109 11143 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.07 1 – 1.14 0.0389 1045 10484 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.04 0.989 – 1.09 0.132 1880 18816 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.01 0.957 – 1.06 0.741 1492 14932 exclusion phecode
739 Contracture of joint Musculoskeletal 1.09 0.996 – 1.2 0.06 486 4832 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.01 0.997 – 1.02 0.122 27234 228547 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.02 1 – 1.03 0.0395 17172 166993 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.02 0.994 – 1.04 0.153 8837 88428 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.93 0.833 – 1.04 0.201 347 3422 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.966 0.887 – 1.05 0.435 588 5886 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.997 0.978 – 1.02 0.721 12000 121066 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.01 0.979 – 1.05 0.451 3512 35228 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 1.14 0.926 – 1.4 0.217 101 1010 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1 0.922 – 1.09 0.97 605 6081 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 0.902 0.763 – 1.07 0.229 149 1512 exclusion phecode
741.4 Joint effusions Musculoskeletal 1.01 0.956 – 1.07 0.743 1401 14008 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.04 0.858 – 1.25 0.715 107 1089 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.952 0.721 – 1.26 0.728 52 525 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1 0.964 – 1.04 0.911 2822 28171 exclusion phecode
742.1 Loose body in joint Musculoskeletal 0.915 0.816 – 1.03 0.125 327 3292 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.962 0.785 – 1.18 0.709 95 956 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.08 0.982 – 1.18 0.113 494 4936 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.995 0.95 – 1.04 0.84 1983 19759 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.02 0.996 – 1.04 0.105 7358 74715 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.02 0.997 – 1.05 0.0807 6213 63191 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.02 0.991 – 1.05 0.178 5450 54836 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 1.09 0.986 – 1.2 0.0947 446 5188 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.03 0.945 – 1.13 0.464 506 5112 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.95 0.884 – 1.02 0.164 806 8056 exclusion phecode
745 Pain in joint Musculoskeletal 0.964 0.942 – 0.987 0.00211 7877 78839 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.982 0.944 – 1.02 0.357 2739 27609 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.978 0.939 – 1.02 0.285 2568 25890 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.956 0.879 – 1.04 0.3 579 5771 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.01 0.886 – 1.16 0.849 228 2321 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1 0.952 – 1.05 0.998 1767 17892 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.03 0.88 – 1.22 0.684 164 1665 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.25 0.94 – 1.67 0.124 51 502 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.985 0.875 – 1.11 0.809 297 3003 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 1.06 0.98 – 1.15 0.144 662 6786 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.06 0.942 – 1.19 0.346 316 3210 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.15 0.984 – 1.34 0.0801 181 1884 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.08 0.969 – 1.21 0.161 342 3529 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.06 0.922 – 1.22 0.415 215 2229 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.18 0.977 – 1.44 0.0851 113 1168 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.985 0.934 – 1.04 0.568 1494 15126 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.974 0.901 – 1.05 0.507 686 6859 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.03 0.937 – 1.13 0.525 451 4506 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.872 0.758 – 1 0.0567 218 2178 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.01 0.94 – 1.08 0.796 811 8289 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 1.07 0.969 – 1.18 0.181 412 4193 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.887 0.792 – 0.993 0.0379 321 3314 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.985 0.879 – 1.1 0.797 325 3277 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 0.959 0.843 – 1.09 0.524 251 2532 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.974 0.845 – 1.12 0.717 206 2088 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.01 0.807 – 1.27 0.917 77 771 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.1 0.916 – 1.32 0.313 125 1253 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.991 0.784 – 1.25 0.939 75 747 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.963 0.79 – 1.17 0.708 107 1088 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.02 0.922 – 1.13 0.712 418 4231 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.938 0.815 – 1.08 0.375 208 2064 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.986 0.84 – 1.16 0.864 157 1608 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.985 0.808 – 1.2 0.882 105 1061 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.01 0.931 – 1.1 0.749 578 5799 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.1 0.878 – 1.37 0.414 80 803 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.03 0.937 – 1.14 0.508 428 4302 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.951 0.803 – 1.13 0.559 146 1695 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.799 0.616 – 1.04 0.0932 58 822 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.802 0.695 – 0.925 0.00248 212 2133 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.896 0.732 – 1.1 0.288 95 951 exclusion phecode
760 Back pain Symptoms 0.992 0.972 – 1.01 0.404 10970 110049 exclusion phecode
761 Cervicalgia Symptoms 0.975 0.928 – 1.02 0.305 1770 17665 exclusion phecode
764 Sciatica Symptoms 0.929 0.89 – 0.97 0.000737 2345 23420 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.02 0.96 – 1.08 0.519 1157 11592 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.02 0.943 – 1.11 0.574 621 6233 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.03 0.96 – 1.1 0.408 859 8591 exclusion phecode
771.1 Swelling of limb Symptoms 1.01 0.982 – 1.04 0.43 4505 45709 exclusion phecode
772 Symptoms of the muscles Symptoms 0.989 0.913 – 1.07 0.787 647 6494 exclusion phecode
773 Pain in limb Symptoms 1.01 0.984 – 1.04 0.464 6101 61445 exclusion phecode
780 Hypothermia/Chills Symptoms 0.92 0.784 – 1.08 0.302 165 1695 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.993 0.947 – 1.04 0.767 1849 18493 exclusion phecode
782.3 Edema Symptoms 0.988 0.939 – 1.04 0.654 1591 16180 exclusion phecode
782.6 Pallor and flushing Symptoms 1.15 0.983 – 1.34 0.0806 167 1718 exclusion phecode
783 Fever of unknown origin Symptoms 0.954 0.922 – 0.987 0.00613 3651 38630 exclusion phecode
785 Abdominal pain Symptoms 1 0.99 – 1.01 0.858 39178 298605 exclusion phecode
788 Syncope and collapse Symptoms 0.989 0.967 – 1.01 0.311 8879 89516 exclusion phecode
789 Nausea and vomiting Symptoms 1 0.984 – 1.02 0.748 11018 114503 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.14 0.959 – 1.35 0.139 143 1479 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 0.916 0.733 – 1.15 0.443 83 823 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.01 0.988 – 1.04 0.303 6189 62558 exclusion phecode
791 Gangrene Symptoms 1.02 0.93 – 1.11 0.725 531 5415 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.947 0.766 – 1.17 0.613 97 954 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.03 0.859 – 1.22 0.781 130 1320 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.04 0.953 – 1.13 0.379 556 5565 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.949 0.791 – 1.14 0.57 120 1193 exclusion phecode
797 Shock Symptoms 1.12 0.946 – 1.31 0.195 150 1537 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.08 0.883 – 1.31 0.467 101 1006 exclusion phecode
798 Malaise and fatigue Symptoms 0.992 0.957 – 1.03 0.645 3272 33695 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 0.94 0.864 – 1.02 0.153 583 5850 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1 0.977 – 1.03 0.935 6944 69429 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.975 0.928 – 1.02 0.299 1785 17887 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.976 0.832 – 1.15 0.767 166 1663 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.02 0.973 – 1.06 0.437 2128 21350 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.981 0.911 – 1.06 0.608 758 7549 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.997 0.954 – 1.04 0.908 2178 21792 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1 0.958 – 1.05 0.839 1816 18148 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 0.995 0.922 – 1.07 0.907 707 7099 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 0.999 0.977 – 1.02 0.924 8202 81902 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 0.996 0.947 – 1.05 0.874 1668 16655 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.02 0.991 – 1.05 0.178 5165 51560 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.938 0.89 – 0.99 0.019 1500 14996 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.995 0.96 – 1.03 0.802 3301 33021 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.959 0.906 – 1.01 0.144 1340 13407 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.01 0.932 – 1.08 0.889 764 7645 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.951 0.898 – 1.01 0.085 1287 12840 exclusion phecode
817 Concussion Injuries & Poisonings 1.04 0.908 – 1.19 0.58 241 2400 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.02 0.935 – 1.12 0.621 512 5139 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.01 0.97 – 1.05 0.713 2922 29286 exclusion phecode
823 Torus fracture Injuries & Poisonings 1.02 0.968 – 1.07 0.484 1654 16543 exclusion phecode
830 Dislocation Injuries & Poisonings 1.03 0.983 – 1.08 0.231 2061 20642 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 1.02 1 – 1.03 0.0429 15052 150508 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.998 0.913 – 1.09 0.964 517 5190 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.988 0.898 – 1.09 0.797 464 4642 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.02 0.988 – 1.05 0.267 5063 52001 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.03 0.878 – 1.21 0.713 156 1549 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 0.995 0.895 – 1.11 0.933 361 4950 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.998 0.95 – 1.05 0.947 1722 17960 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.979 0.923 – 1.04 0.493 1196 12281 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.98 0.945 – 1.02 0.289 3117 31236 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.02 0.985 – 1.06 0.263 3184 32243 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 0.874 0.691 – 1.11 0.26 67 675 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.01 0.972 – 1.04 0.732 3456 34570 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.958 0.846 – 1.08 0.497 268 2674 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 1 0.867 – 1.16 0.968 193 1930 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1 0.967 – 1.04 0.829 2864 28687 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.07 0.936 – 1.23 0.309 214 2162 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.951 0.733 – 1.23 0.705 65 664 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.02 0.99 – 1.06 0.169 4011 40160 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.853 0.638 – 1.14 0.281 52 523 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.991 0.8 – 1.23 0.935 90 889 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1 0.865 – 1.16 0.963 176 1752 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.06 0.961 – 1.16 0.26 473 4672 exclusion phecode
873 Broken tooth Injuries & Poisonings 1.01 0.878 – 1.15 0.925 228 2255 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.01 0.856 – 1.18 0.949 164 1695 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 0.972 0.821 – 1.15 0.739 154 1555 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 0.995 0.94 – 1.05 0.857 1306 12997 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 0.989 0.959 – 1.02 0.51 4177 42136 exclusion phecode
916 Contusion Injuries & Poisonings 1 0.948 – 1.06 0.934 1421 14306 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.986 0.844 – 1.15 0.861 176 1793 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.09 0.978 – 1.2 0.125 379 3827 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 1.11 0.972 – 1.26 0.128 249 2481 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.04 0.989 – 1.08 0.138 2028 20714 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1 0.874 – 1.15 0.955 224 2220 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.16 0.944 – 1.43 0.157 97 1031 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.05 0.963 – 1.15 0.26 537 5441 exclusion phecode
947 Urticaria Injuries & Poisonings 0.974 0.876 – 1.08 0.633 360 3667 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.01 0.907 – 1.12 0.913 391 3947 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.912 0.826 – 1.01 0.0685 422 4175 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.953 0.841 – 1.08 0.451 265 2663 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.02 0.929 – 1.12 0.67 483 4874 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 0.71 0.545 – 0.925 0.0113 52 551 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.2 0.945 – 1.53 0.134 74 734 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.985 0.97 – 1 0.0591 17756 179213 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.983 0.967 – 1 0.0471 15544 156933 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 0.996 0.899 – 1.1 0.934 410 4143 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.03 0.965 – 1.11 0.343 856 8615 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.01 0.906 – 1.13 0.861 358 3671 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.01 0.907 – 1.13 0.83 352 3603 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.934 0.813 – 1.07 0.333 216 2211 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.01 0.887 – 1.14 0.935 275 2776 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.01 0.892 – 1.15 0.855 268 2716 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.979 0.953 – 1.01 0.113 5944 60240 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.04 0.982 – 1.11 0.169 1096 11333 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.939 0.856 – 1.03 0.19 472 4736 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.936 0.844 – 1.04 0.211 394 3999 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1 0.914 – 1.09 0.997 507 5081 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.974 0.893 – 1.06 0.548 561 5770 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 0.979 0.934 – 1.03 0.373 1920 19379 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.93 0.801 – 1.08 0.345 187 1895 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.934 0.824 – 1.06 0.285 269 2680 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.775 0.617 – 0.973 0.0279 84 846 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 0.852 0.7 – 1.04 0.11 105 1072 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.12 0.911 – 1.37 0.288 101 1003 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.86 0.667 – 1.11 0.242 63 632 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.01 0.782 – 1.3 0.938 58 572 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.991 0.866 – 1.13 0.897 226 2306 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.07 0.991 – 1.16 0.0816 682 6899 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.99 0.86 – 1.14 0.89 198 1979 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.02 0.789 – 1.33 0.859 62 610 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 0.858 0.702 – 1.05 0.133 103 1039 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 1.04 0.858 – 1.26 0.702 111 1121 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.722 0.578 – 0.902 0.00404 85 878 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 0.983 0.945 – 1.02 0.387 2756 30740 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 0.955 0.919 – 0.993 0.0212 2779 29835 exclusion phecode
994.2 Sepsis Injuries & Poisonings 0.955 0.919 – 0.993 0.0212 2779 29835 exclusion phecode
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