Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Estimated glomerular filtration rate based on cystatin C UK Biobank (UKB) PheWAS analysis

Estimated glomerular filtration rate based on cystatin C — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID exprsweb-egfr-cystatinc-egfrcys-overall-ea-plink-ukb-20211120Legacy PLINKC+T (GT)Large GWAS

Evaluation cohort: UK Biobank (UKB).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: study-defined normal-range subset.

For this ExPRS, the exclusion sensitivity scan keeps only the study-defined normal-range subset for Estimated glomerular filtration rate based on cystatin C before rerunning the PheWAS. The preserved release does not include numeric bounds for this trait. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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Signal overview

The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.

90 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.01 0.991 – 1.04 0.241 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.01 0.967 – 1.05 0.765 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.03 0.954 – 1.12 0.419 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 1.01 0.946 – 1.09 0.695 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 0.988 0.758 – 1.29 0.926 55 550 all phecode
010 Tuberculosis Infectious Diseases 0.978 0.834 – 1.15 0.783 166 1659 all phecode
038 Septicemia Infectious Diseases 1.01 0.978 – 1.04 0.545 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 0.977 0.91 – 1.05 0.525 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.02 0.929 – 1.12 0.697 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 1.01 0.988 – 1.03 0.485 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.04 1.01 – 1.08 0.0253 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 1 0.951 – 1.05 0.972 1641 16433 all phecode
041.4 E. coli Infectious Diseases 1.05 1.01 – 1.09 0.021 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 0.93 0.839 – 1.03 0.167 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.803 0.644 – 1 0.0523 95 949 all phecode
054 Herpes simplex Infectious Diseases 1.05 0.92 – 1.21 0.446 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 0.982 0.903 – 1.07 0.678 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 1 0.79 – 1.27 0.978 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 1 0.847 – 1.19 0.967 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.03 0.903 – 1.17 0.686 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 0.86 0.755 – 0.98 0.0236 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 0.937 0.849 – 1.03 0.197 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.04 0.885 – 1.23 0.624 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.04 0.866 – 1.24 0.688 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 0.999 0.936 – 1.07 0.969 1004 10036 all phecode
079 Viral infection Infectious Diseases 0.983 0.945 – 1.02 0.382 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 0.902 0.699 – 1.17 0.431 64 640 all phecode
080 Postoperative infection Infectious Diseases 1.01 0.977 – 1.04 0.614 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.04 0.994 – 1.08 0.09 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.909 0.704 – 1.17 0.465 71 709 all phecode
1000 Burns Injuries & Poisonings 0.941 0.863 – 1.03 0.17 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 1.07 1.01 – 1.13 0.0209 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1 0.974 – 1.03 0.898 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.01 0.896 – 1.13 0.899 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 1.03 0.98 – 1.09 0.23 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 0.936 0.821 – 1.07 0.32 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 1.03 0.912 – 1.17 0.619 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 0.979 0.919 – 1.04 0.524 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 1.02 1 – 1.05 0.0459 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 0.999 0.973 – 1.03 0.958 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 0.996 0.975 – 1.02 0.732 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 1 0.821 – 1.23 0.971 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.06 0.944 – 1.18 0.341 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.13 0.893 – 1.43 0.305 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 0.967 0.936 – 0.998 0.0397 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.01 0.998 – 1.03 0.079 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.02 0.907 – 1.16 0.7 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 1.04 0.917 – 1.17 0.572 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.07 0.845 – 1.34 0.591 74 756 all phecode
110.12 Althete's foot Infectious Diseases 0.995 0.839 – 1.18 0.956 141 1410 all phecode
112 Candidiasis Infectious Diseases 0.98 0.937 – 1.03 0.382 2126 21275 all phecode
117 Mycoses Infectious Diseases 0.977 0.862 – 1.11 0.718 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 1.01 0.858 – 1.18 0.94 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 0.991 0.79 – 1.24 0.939 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 1.03 0.81 – 1.3 0.823 69 689 all phecode
134 Helminthiases Infectious Diseases 1.01 0.853 – 1.21 0.868 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 0.985 0.811 – 1.2 0.883 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.02 0.882 – 1.17 0.817 205 2050 all phecode
145 Cancer of mouth Neoplasms 1 0.923 – 1.09 0.978 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 0.95 0.845 – 1.07 0.385 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.07 0.88 – 1.31 0.486 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 1 0.763 – 1.32 0.978 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.902 0.83 – 0.98 0.0153 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 0.863 0.755 – 0.987 0.031 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 0.919 0.809 – 1.04 0.193 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 0.965 0.738 – 1.26 0.794 57 570 all phecode
150 Cancer of esophagus Neoplasms 0.929 0.861 – 1 0.0552 762 7630 all phecode
151 Cancer of stomach Neoplasms 1 0.917 – 1.09 0.991 569 5696 all phecode
153 Colorectal cancer Neoplasms 0.995 0.965 – 1.03 0.732 4580 45799 all phecode
153.2 Colon cancer Neoplasms 1.01 0.971 – 1.04 0.708 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.962 0.92 – 1.01 0.0859 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.02 0.919 – 1.12 0.749 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.02 0.872 – 1.2 0.796 158 1580 all phecode
157 Pancreatic cancer Neoplasms 0.966 0.891 – 1.05 0.408 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.996 0.934 – 1.06 0.894 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.987 0.96 – 1.01 0.346 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.03 0.892 – 1.19 0.673 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.925 0.8 – 1.07 0.292 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.983 0.85 – 1.14 0.822 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 1.31 1.02 – 1.69 0.0324 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 0.995 0.957 – 1.03 0.785 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.02 0.978 – 1.07 0.332 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 1.08 0.977 – 1.19 0.136 437 4364 all phecode
170.1 Bone cancer Neoplasms 1.26 1.06 – 1.5 0.00861 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 1.02 0.914 – 1.15 0.691 331 3303 all phecode
172 Skin cancer Neoplasms 0.994 0.976 – 1.01 0.504 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.974 0.936 – 1.01 0.203 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 0.978 0.94 – 1.02 0.27 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.994 0.975 – 1.01 0.537 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.09 1.01 – 1.18 0.0354 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.955 0.82 – 1.11 0.556 181 1818 all phecode
174 Breast cancer Neoplasms 1.01 0.987 – 1.02 0.561 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 1 0.986 – 1.02 0.618 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1 0.983 – 1.02 0.855 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.09 0.909 – 1.31 0.348 115 1148 all phecode
175 Acquired absence of breast Neoplasms 0.989 0.948 – 1.03 0.597 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 1 0.961 – 1.05 0.832 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 0.997 0.881 – 1.13 0.963 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.992 0.948 – 1.04 0.738 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 0.973 0.918 – 1.03 0.351 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 1 0.949 – 1.06 0.919 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.01 0.95 – 1.08 0.675 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.01 0.947 – 1.08 0.714 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.922 0.818 – 1.04 0.184 305 3049 all phecode
185 Cancer of prostate Neoplasms 1.02 0.995 – 1.05 0.116 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 1.03 0.936 – 1.13 0.552 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.16 0.917 – 1.48 0.214 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.986 0.876 – 1.11 0.817 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.04 0.862 – 1.25 0.7 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.999 0.968 – 1.03 0.964 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.99 0.929 – 1.05 0.742 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.986 0.925 – 1.05 0.66 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.05 0.816 – 1.34 0.717 66 660 all phecode
189.2 Cancer of bladder Neoplasms 0.99 0.949 – 1.03 0.65 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.98 0.937 – 1.02 0.377 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.05 0.888 – 1.24 0.571 144 1439 all phecode
190 Cancer of eye Neoplasms 0.872 0.742 – 1.02 0.0963 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.975 0.901 – 1.06 0.537 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 1 0.92 – 1.1 0.928 566 5650 all phecode
191.11 Cancer of brain Neoplasms 1.01 0.922 – 1.1 0.842 525 5240 all phecode
193 Thyroid cancer Neoplasms 1.14 1.03 – 1.27 0.0123 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 0.931 0.752 – 1.15 0.516 95 949 all phecode
195 Cancer, suspected or other Neoplasms 0.994 0.979 – 1.01 0.486 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 0.991 0.975 – 1.01 0.291 16267 159497 all phecode
197 Chemotherapy Neoplasms 1.01 0.992 – 1.02 0.414 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 1.01 0.991 – 1.03 0.281 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.03 0.997 – 1.05 0.0785 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.985 0.943 – 1.03 0.488 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.01 0.96 – 1.06 0.679 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.01 0.969 – 1.05 0.7 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.984 0.916 – 1.06 0.654 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.02 0.978 – 1.07 0.324 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.859 0.734 – 1 0.0566 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 0.977 0.925 – 1.03 0.398 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 0.947 0.769 – 1.17 0.611 95 950 all phecode
200 Myeloproliferative disease Neoplasms 0.977 0.915 – 1.04 0.483 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 1.04 0.934 – 1.15 0.497 387 3867 all phecode
201 Hodgkin's disease Neoplasms 0.934 0.82 – 1.06 0.299 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.01 0.967 – 1.05 0.661 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.01 0.958 – 1.05 0.828 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 1.16 1.05 – 1.29 0.00511 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 1.03 0.951 – 1.12 0.434 581 5824 all phecode
204 Leukemia Neoplasms 0.983 0.935 – 1.03 0.512 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 0.983 0.902 – 1.07 0.693 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.01 0.757 – 1.34 0.965 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.978 0.893 – 1.07 0.633 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 0.976 0.887 – 1.07 0.62 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 0.965 0.861 – 1.08 0.534 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.07 0.909 – 1.27 0.401 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 0.95 0.87 – 1.04 0.252 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 0.996 0.982 – 1.01 0.625 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.956 0.895 – 1.02 0.185 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.03 1 – 1.06 0.0426 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1 0.896 – 1.12 0.983 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.05 0.938 – 1.18 0.38 318 3187 all phecode
214 Lipoma Neoplasms 1 0.977 – 1.03 0.829 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.01 0.981 – 1.04 0.468 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.08 1.02 – 1.15 0.0122 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 1 0.981 – 1.03 0.707 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.03 0.954 – 1.12 0.419 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1.03 0.947 – 1.12 0.505 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 1 0.98 – 1.02 0.987 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 0.999 0.979 – 1.02 0.892 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.896 0.802 – 1 0.0521 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 0.982 0.93 – 1.04 0.524 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.923 0.803 – 1.06 0.26 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 1.26 1.08 – 1.48 0.00292 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.13 0.972 – 1.31 0.112 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 1.12 0.941 – 1.33 0.206 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.21 0.952 – 1.52 0.12 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.946 0.878 – 1.02 0.138 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.952 0.883 – 1.03 0.204 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.846 0.637 – 1.12 0.251 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.902 0.792 – 1.03 0.119 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.05 0.977 – 1.12 0.193 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.1 0.948 – 1.27 0.214 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.09 0.982 – 1.21 0.107 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.01 0.893 – 1.13 0.933 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.957 0.908 – 1.01 0.0961 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.03 0.989 – 1.08 0.145 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.05 0.97 – 1.14 0.22 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.981 0.922 – 1.04 0.542 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.06 0.96 – 1.16 0.26 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.933 0.862 – 1.01 0.0895 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.01 0.961 – 1.06 0.762 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 0.97 0.882 – 1.07 0.538 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 0.99 0.806 – 1.22 0.925 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 0.985 0.826 – 1.17 0.864 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 0.982 0.965 – 0.999 0.0343 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.06 1 – 1.13 0.0516 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.884 0.714 – 1.09 0.256 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.977 0.96 – 0.994 0.00836 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 0.884 0.782 – 1 0.0494 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.87 0.756 – 1 0.0534 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.882 0.765 – 1.02 0.0851 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 0.952 0.858 – 1.06 0.358 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 0.995 0.981 – 1.01 0.513 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.954 0.917 – 0.993 0.0201 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.86 0.749 – 0.988 0.0326 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.934 0.741 – 1.18 0.562 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.955 0.869 – 1.05 0.34 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 0.926 0.788 – 1.09 0.355 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.992 0.977 – 1.01 0.295 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.08 0.892 – 1.32 0.417 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.14 0.99 – 1.31 0.0682 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.991 0.928 – 1.06 0.791 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 0.994 0.907 – 1.09 0.898 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 0.968 0.893 – 1.05 0.417 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.958 0.843 – 1.09 0.511 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.989 0.894 – 1.1 0.834 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.927 0.769 – 1.12 0.425 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.01 0.907 – 1.13 0.839 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.979 0.925 – 1.04 0.454 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 0.928 0.867 – 0.993 0.0314 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.06 0.992 – 1.14 0.0845 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.05 0.98 – 1.13 0.158 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.09 0.919 – 1.29 0.331 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1 0.926 – 1.08 0.965 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.04 0.897 – 1.21 0.608 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.18 0.969 – 1.45 0.0991 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.961 0.847 – 1.09 0.545 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.702 0.551 – 0.895 0.00427 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.09 0.935 – 1.28 0.264 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.973 0.896 – 1.06 0.507 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.03 0.889 – 1.2 0.658 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.94 0.768 – 1.15 0.551 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.22 0.97 – 1.53 0.0891 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.977 0.876 – 1.09 0.68 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.979 0.877 – 1.09 0.703 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 0.985 0.861 – 1.13 0.823 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.953 0.825 – 1.1 0.508 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 1.07 0.91 – 1.25 0.424 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.06 0.896 – 1.25 0.509 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.928 0.761 – 1.13 0.46 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 0.949 0.798 – 1.13 0.552 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.96 0.833 – 1.11 0.576 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 0.862 0.641 – 1.16 0.328 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 0.97 0.903 – 1.04 0.397 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 0.98 0.924 – 1.04 0.506 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.01 0.939 – 1.09 0.756 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.973 0.883 – 1.07 0.582 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.942 0.747 – 1.19 0.611 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.959 0.839 – 1.09 0.532 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 1.06 0.945 – 1.18 0.338 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1 0.895 – 1.12 0.962 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.01 0.893 – 1.14 0.869 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 0.978 0.848 – 1.13 0.759 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 0.99 0.819 – 1.2 0.916 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.08 0.853 – 1.37 0.52 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.1 0.936 – 1.29 0.251 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.09 0.92 – 1.3 0.312 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.992 0.981 – 1 0.174 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.992 0.981 – 1 0.161 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.993 0.982 – 1.01 0.265 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1 0.768 – 1.3 0.999 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.05 0.899 – 1.23 0.527 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.06 0.919 – 1.21 0.439 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1 0.97 – 1.04 0.828 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 0.99 0.954 – 1.03 0.598 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.08 0.887 – 1.31 0.455 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.06 0.979 – 1.15 0.147 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.07 0.982 – 1.17 0.123 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.06 1.02 – 1.11 0.00681 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 1.05 0.974 – 1.14 0.193 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.1 0.99 – 1.22 0.0771 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.05 0.989 – 1.11 0.11 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1 0.856 – 1.18 0.962 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.01 0.985 – 1.03 0.455 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.02 0.993 – 1.06 0.131 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.1 0.964 – 1.25 0.162 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 0.996 0.949 – 1.05 0.864 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.02 0.95 – 1.09 0.661 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.07 1.01 – 1.13 0.0184 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 0.984 0.926 – 1.05 0.603 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 1 0.94 – 1.07 0.97 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 0.879 0.717 – 1.08 0.213 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 0.99 0.953 – 1.03 0.62 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 1.02 0.93 – 1.12 0.639 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 1.01 0.844 – 1.2 0.926 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.01 0.945 – 1.08 0.745 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.982 0.883 – 1.09 0.738 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.05 0.923 – 1.2 0.436 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1 0.753 – 1.33 0.993 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.02 0.996 – 1.04 0.113 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 1.02 0.998 – 1.04 0.0722 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 0.865 0.693 – 1.08 0.201 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.08 0.843 – 1.37 0.555 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.09 0.962 – 1.24 0.176 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 1.07 0.935 – 1.23 0.32 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.15 0.972 – 1.36 0.104 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.07 0.942 – 1.22 0.285 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 1.01 0.982 – 1.03 0.647 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1 0.981 – 1.03 0.691 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1 0.91 – 1.1 0.968 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 1.03 0.966 – 1.09 0.396 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 1.03 0.965 – 1.09 0.399 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 1.01 0.939 – 1.09 0.745 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.16 0.995 – 1.34 0.0576 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 1.02 0.875 – 1.19 0.809 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 1.06 0.812 – 1.39 0.659 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 0.986 0.838 – 1.16 0.864 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 0.936 0.715 – 1.23 0.629 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.04 0.833 – 1.29 0.747 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.05 0.885 – 1.25 0.575 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.993 0.812 – 1.21 0.942 103 1059 all phecode
284 Aplastic anemia Hematopoietic 1.06 0.963 – 1.17 0.234 435 4357 all phecode
285 Other anemias Hematopoietic 0.999 0.981 – 1.02 0.946 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.973 0.86 – 1.1 0.669 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.02 0.945 – 1.1 0.6 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.08 0.978 – 1.19 0.133 414 4147 all phecode
286 Coagulation defects Hematopoietic 0.979 0.914 – 1.05 0.536 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 0.933 0.844 – 1.03 0.168 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 0.946 0.76 – 1.18 0.622 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.896 0.791 – 1.01 0.0818 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 0.977 0.759 – 1.26 0.857 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.16 0.938 – 1.44 0.169 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.981 0.883 – 1.09 0.721 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.03 0.977 – 1.08 0.283 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.01 0.845 – 1.21 0.898 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 1.27 0.991 – 1.64 0.0585 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 1.01 0.961 – 1.07 0.631 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 0.862 0.776 – 0.957 0.00541 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.905 0.712 – 1.15 0.414 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 1.02 0.986 – 1.05 0.253 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 1.01 0.971 – 1.04 0.707 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 1.01 0.97 – 1.04 0.74 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 1.21 0.961 – 1.53 0.104 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.985 0.918 – 1.06 0.671 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.941 0.833 – 1.06 0.329 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 1 0.961 – 1.04 0.975 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 0.937 0.855 – 1.03 0.168 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 0.988 0.877 – 1.11 0.843 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.11 0.899 – 1.38 0.327 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1 0.959 – 1.05 0.846 1929 19281 all phecode
290.1 Dementias Mental Disorders 0.981 0.919 – 1.05 0.575 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 1.03 0.93 – 1.13 0.602 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 0.937 0.81 – 1.08 0.383 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.979 0.903 – 1.06 0.618 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.04 0.826 – 1.3 0.754 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.942 0.876 – 1.01 0.108 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.97 0.807 – 1.17 0.75 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.893 0.787 – 1.01 0.0801 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 1 0.907 – 1.1 0.998 436 4376 all phecode
292 Neurological disorders Mental Disorders 1.02 0.995 – 1.06 0.105 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.01 0.958 – 1.06 0.722 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.903 0.774 – 1.05 0.192 190 1907 all phecode
292.3 Memory loss Mental Disorders 0.994 0.92 – 1.07 0.885 696 6978 all phecode
292.4 Altered mental status Mental Disorders 1.04 0.996 – 1.09 0.072 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 1.01 0.901 – 1.14 0.834 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 1.01 0.969 – 1.06 0.569 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.988 0.923 – 1.06 0.74 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.976 0.908 – 1.05 0.506 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 0.986 0.905 – 1.07 0.742 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 1.05 0.898 – 1.22 0.566 178 1780 all phecode
295.3 Psychosis Mental Disorders 0.886 0.752 – 1.04 0.15 169 1710 all phecode
296 Mood disorders Mental Disorders 1.02 1 – 1.04 0.0248 12372 123822 all phecode
296.1 Bipolar Mental Disorders 0.998 0.936 – 1.06 0.941 1059 10599 all phecode
296.2 Depression Mental Disorders 1.02 1 – 1.04 0.0191 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 1.02 0.913 – 1.13 0.76 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.9 0.799 – 1.01 0.0831 311 3070 all phecode
300 Anxiety disorders Mental Disorders 0.991 0.967 – 1.02 0.48 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 0.993 0.967 – 1.02 0.58 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 0.911 0.769 – 1.08 0.277 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.01 0.935 – 1.09 0.796 707 7065 all phecode
300.13 Phobia Mental Disorders 0.998 0.91 – 1.09 0.965 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.875 0.731 – 1.05 0.149 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 1.17 0.893 – 1.53 0.257 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 0.994 0.829 – 1.19 0.948 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.02 0.846 – 1.24 0.802 113 1129 all phecode
301 Personality disorders Mental Disorders 1.15 1.03 – 1.28 0.0125 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.07 0.886 – 1.28 0.502 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 1.03 0.911 – 1.16 0.642 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.03 0.935 – 1.13 0.575 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 0.996 0.892 – 1.11 0.947 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 1.05 0.874 – 1.26 0.613 123 1229 all phecode
304 Adjustment reaction Mental Disorders 0.96 0.848 – 1.09 0.515 293 2936 all phecode
305.2 Eating disorder Mental Disorders 0.937 0.753 – 1.17 0.56 90 900 all phecode
306 Other mental disorder Mental Disorders 1 0.992 – 1.02 0.457 28056 230087 all phecode
306.9 Tension headache Mental Disorders 1.03 0.913 – 1.15 0.668 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 0.987 0.786 – 1.24 0.908 76 770 all phecode
313.3 Autism Mental Disorders 1.16 0.894 – 1.5 0.269 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 0.998 0.895 – 1.11 0.976 351 3517 all phecode
315.1 Learning disorder Mental Disorders 0.906 0.767 – 1.07 0.244 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 0.952 0.759 – 1.2 0.673 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 0.994 0.966 – 1.02 0.679 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.821 0.625 – 1.08 0.157 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 1 0.983 – 1.02 0.924 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 1 0.98 – 1.02 0.878 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 0.965 0.898 – 1.04 0.324 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 0.99 0.976 – 1.01 0.204 19359 185465 all phecode
320 Meningitis Neurological 0.962 0.872 – 1.06 0.439 444 4447 all phecode
323 Encephalitis Neurological 1.06 0.954 – 1.18 0.267 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 1.15 0.92 – 1.43 0.223 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 1.16 1.03 – 1.31 0.0145 292 2916 all phecode
327 Sleep disorders Neurological 1.09 1.03 – 1.16 0.00268 1164 11659 all phecode
327.3 Sleep apnea Neurological 0.997 0.966 – 1.03 0.829 4428 44318 all phecode
327.4 Insomnia Neurological 1 0.853 – 1.17 0.995 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 1.07 0.903 – 1.27 0.435 136 1390 all phecode
331 Other cerebral degenerations Neurological 1.01 0.95 – 1.07 0.74 1142 11416 all phecode
331.1 Hydrocephalus Neurological 0.96 0.874 – 1.06 0.398 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 1.07 0.965 – 1.18 0.21 430 4298 all phecode
332 Parkinson's disease Neurological 1.03 0.972 – 1.1 0.29 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.02 0.957 – 1.1 0.487 894 8954 all phecode
333.1 Essential tremor Neurological 1.08 0.944 – 1.24 0.258 216 2157 all phecode
333.2 Myoclonus Neurological 1.11 0.9 – 1.37 0.332 96 958 all phecode
333.4 Torsion dystonia Neurological 0.922 0.807 – 1.05 0.233 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 1.01 0.961 – 1.06 0.727 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 1.18 0.985 – 1.42 0.0716 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 1.06 0.929 – 1.21 0.39 245 2446 all phecode
335 Multiple sclerosis Neurological 1 0.95 – 1.06 0.866 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 0.997 0.88 – 1.13 0.957 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 0.864 0.675 – 1.11 0.245 72 719 all phecode
338 Pain Neurological 1.07 0.998 – 1.15 0.0578 768 7692 all phecode
338.1 Acute pain Neurological 1.08 0.977 – 1.2 0.131 394 3937 all phecode
338.2 Chronic pain Neurological 1.04 0.935 – 1.15 0.486 380 3817 all phecode
339 Other headache syndromes Neurological 1.01 0.986 – 1.03 0.43 7819 78241 all phecode
340 Migraine Neurological 0.981 0.943 – 1.02 0.326 2860 28602 all phecode
340.1 Migrain with aura Neurological 0.902 0.781 – 1.04 0.157 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.995 0.874 – 1.13 0.934 252 2535 all phecode
342 Hemiplegia Neurological 1 0.95 – 1.06 0.945 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 0.804 0.673 – 0.961 0.0164 145 1450 all phecode
344 Other paralytic syndromes Neurological 1.06 0.976 – 1.14 0.173 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.01 0.979 – 1.04 0.604 5023 50270 all phecode
345.1 Epilepsy Neurological 1.02 0.951 – 1.09 0.583 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 1.11 1.01 – 1.22 0.0272 439 4385 all phecode
345.12 Partial epilepsy Neurological 0.998 0.882 – 1.13 0.969 277 2776 all phecode
345.3 Convulsions Neurological 0.978 0.936 – 1.02 0.317 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.05 0.891 – 1.25 0.542 144 1438 all phecode
348 Other conditions of brain Neurological 0.967 0.897 – 1.04 0.372 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 0.988 0.871 – 1.12 0.845 268 2678 all phecode
348.4 Cerebral cysts Neurological 1 0.839 – 1.2 0.972 133 1350 all phecode
348.7 Coma Neurological 1.03 0.931 – 1.15 0.528 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 0.946 0.828 – 1.08 0.41 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 0.985 0.889 – 1.09 0.777 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.1 0.991 – 1.23 0.0715 342 3414 all phecode
350 Abnormal movement Neurological 1.04 1 – 1.08 0.0411 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 1.03 0.962 – 1.1 0.388 887 8852 all phecode
350.2 Abnormality of gait Neurological 1.04 0.99 – 1.1 0.112 1596 15969 all phecode
350.3 Lack of coordination Neurological 1.08 0.977 – 1.2 0.13 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.995 0.765 – 1.29 0.968 54 540 all phecode
351 Other peripheral nerve disorders Neurological 1 0.983 – 1.02 0.893 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 1.04 0.988 – 1.1 0.129 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.992 0.902 – 1.09 0.873 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.05 0.978 – 1.12 0.185 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 0.997 0.937 – 1.06 0.921 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 0.885 0.726 – 1.08 0.227 114 1138 all phecode
353.2 Nerve root lesions Neurological 1.06 0.814 – 1.37 0.675 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.06 0.906 – 1.24 0.458 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.1 1.04 – 1.16 0.000935 1361 13648 all phecode
358 Myoneural disorders Neurological 1.03 0.898 – 1.18 0.672 211 2109 all phecode
358.1 Myasthenia gravis Neurological 1.05 0.907 – 1.21 0.527 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 1.02 0.927 – 1.12 0.69 465 4646 all phecode
359.1 Muscular dystrophies Neurological 0.822 0.677 – 0.997 0.0469 122 1219 all phecode
359.2 Myopathy Neurological 1.08 0.97 – 1.2 0.161 360 3597 all phecode
360 Disorders of the globe Sense Organs 0.997 0.891 – 1.12 0.954 337 3367 all phecode
360.2 Progressive myopia Sense Organs 1.05 0.922 – 1.19 0.472 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 1.03 0.996 – 1.07 0.0787 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.02 0.968 – 1.08 0.417 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.931 0.723 – 1.2 0.579 68 680 all phecode
362 Other retinal disorders Sense Organs 1.01 0.978 – 1.04 0.522 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.02 0.973 – 1.06 0.469 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.02 0.973 – 1.06 0.471 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.07 0.916 – 1.26 0.381 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 1.09 0.891 – 1.33 0.4 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.03 0.961 – 1.11 0.399 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 1.01 0.867 – 1.17 0.916 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.838 0.662 – 1.06 0.141 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.991 0.823 – 1.19 0.922 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.941 0.801 – 1.1 0.456 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 1.07 0.848 – 1.36 0.563 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.02 0.943 – 1.11 0.588 647 6485 all phecode
364.1 Corneal opacity Sense Organs 1.13 0.915 – 1.39 0.262 90 910 all phecode
364.2 Corneal edema Sense Organs 1.02 0.806 – 1.28 0.883 79 800 all phecode
364.4 Corneal degenerations Sense Organs 1.13 0.977 – 1.3 0.101 201 2017 all phecode
364.41 Keratoconus Sense Organs 1.07 0.862 – 1.32 0.558 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 0.989 0.858 – 1.14 0.881 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.981 0.795 – 1.21 0.857 100 1000 all phecode
365 Glaucoma Sense Organs 1.01 0.98 – 1.04 0.517 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 1.01 0.95 – 1.08 0.704 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 1.02 0.954 – 1.08 0.603 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.958 0.886 – 1.04 0.28 698 6996 all phecode
366 Cataract Sense Organs 1.01 0.992 – 1.02 0.35 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 0.89 0.695 – 1.14 0.352 69 700 all phecode
366.2 Senile cataract Sense Organs 1.01 0.987 – 1.03 0.391 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 1.17 0.965 – 1.41 0.113 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.02 0.975 – 1.06 0.445 2408 24092 all phecode
367.1 Myopia Sense Organs 1.02 0.964 – 1.08 0.48 1251 12519 all phecode
367.2 Astigmatism Sense Organs 0.964 0.828 – 1.12 0.634 190 1899 all phecode
367.8 Hypermetropia Sense Organs 1.05 0.926 – 1.2 0.428 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 1.02 0.941 – 1.1 0.691 719 7198 all phecode
368 Visual disturbances Sense Organs 1.03 0.99 – 1.07 0.153 2962 29648 all phecode
368.1 Amblyopia Sense Organs 0.982 0.898 – 1.07 0.691 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.975 0.903 – 1.05 0.515 727 7288 all phecode
368.3 Anisometropia Sense Organs 1.1 0.94 – 1.29 0.232 154 1548 all phecode
368.4 Visual field defects Sense Organs 1.05 0.938 – 1.17 0.418 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 1.13 1.04 – 1.22 0.00339 612 6115 all phecode
369 Infection of the eye Sense Organs 1.05 0.961 – 1.15 0.28 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 1.01 0.838 – 1.21 0.93 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.935 0.808 – 1.08 0.368 213 2128 all phecode
370 Keratitis Sense Organs 1.03 0.915 – 1.16 0.609 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 0.984 0.828 – 1.17 0.856 141 1408 all phecode
371 Inflammation of the eye Sense Organs 1.02 0.98 – 1.06 0.375 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.05 0.959 – 1.15 0.291 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 0.997 0.955 – 1.04 0.877 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 1 0.929 – 1.08 0.998 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 0.996 0.969 – 1.02 0.778 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 0.96 0.901 – 1.02 0.205 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 0.975 0.929 – 1.02 0.314 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 0.996 0.953 – 1.04 0.856 2204 22031 all phecode
375.2 Epiphora Sense Organs 0.995 0.929 – 1.07 0.895 898 8969 all phecode
376 Disorders of the orbit Sense Organs 0.956 0.768 – 1.19 0.69 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1 0.899 – 1.12 0.96 361 3618 all phecode
377.1 Optic atrophy Sense Organs 1.02 0.779 – 1.33 0.904 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.971 0.808 – 1.17 0.75 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.974 0.921 – 1.03 0.346 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.951 0.888 – 1.02 0.157 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.983 0.854 – 1.13 0.816 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 1.04 0.922 – 1.18 0.494 275 2755 all phecode
379 Other disorders of eye Sense Organs 0.994 0.961 – 1.03 0.711 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 1 0.95 – 1.06 0.894 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.993 0.946 – 1.04 0.782 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.07 0.84 – 1.35 0.598 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.05 0.953 – 1.16 0.318 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.99 0.847 – 1.16 0.896 169 1690 all phecode
380 Disorders of external ear Sense Organs 1.01 0.934 – 1.1 0.765 642 6413 all phecode
380.1 Otitis externa Sense Organs 1.01 0.919 – 1.11 0.865 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 0.99 0.89 – 1.1 0.848 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.964 0.922 – 1.01 0.115 2150 21493 all phecode
381.1 Otitis media Sense Organs 0.958 0.912 – 1.01 0.093 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.989 0.922 – 1.06 0.765 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 0.954 0.823 – 1.11 0.539 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.1 0.944 – 1.29 0.219 171 1709 all phecode
381.9 Otorrhea Sense Organs 0.944 0.833 – 1.07 0.364 281 2807 all phecode
382 Otalgia Sense Organs 1.08 0.961 – 1.21 0.199 308 3084 all phecode
383 Otosclerosis Sense Organs 0.976 0.869 – 1.1 0.68 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.01 0.956 – 1.07 0.675 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.03 0.964 – 1.09 0.403 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.01 0.943 – 1.09 0.71 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 1.01 0.925 – 1.09 0.887 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.981 0.86 – 1.12 0.771 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.06 1.01 – 1.11 0.0304 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 1.12 1.03 – 1.22 0.00583 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 0.987 0.888 – 1.1 0.807 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 1.02 0.95 – 1.1 0.549 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.01 0.978 – 1.04 0.592 4582 45806 all phecode
388 Other disorders of ear Sense Organs 1.15 0.999 – 1.32 0.0515 202 2017 all phecode
389 Hearing loss Sense Organs 0.993 0.962 – 1.03 0.673 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 1.03 0.933 – 1.13 0.584 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 0.919 0.832 – 1.02 0.0985 450 4497 all phecode
389.4 Tinnitus Sense Organs 0.963 0.878 – 1.06 0.421 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.01 0.98 – 1.04 0.546 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 1.02 0.979 – 1.06 0.385 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 1 0.945 – 1.06 0.968 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.04 0.973 – 1.1 0.267 1058 10566 all phecode
395 Heart valve disorders Circulatory System 1.01 0.983 – 1.05 0.361 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.02 0.983 – 1.06 0.29 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.09 0.961 – 1.23 0.18 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.03 0.852 – 1.26 0.73 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.09 0.889 – 1.33 0.417 97 970 all phecode
395.6 Heart valve replaced Circulatory System 0.984 0.933 – 1.04 0.561 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 1.06 0.994 – 1.13 0.0757 1048 10468 all phecode
401 Hypertension Circulatory System 0.991 0.983 – 1 0.0406 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 0.991 0.983 – 1 0.0401 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 0.969 0.924 – 1.02 0.198 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 1.02 0.918 – 1.13 0.728 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.964 0.914 – 1.02 0.17 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 0.963 0.806 – 1.15 0.677 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.01 0.962 – 1.07 0.601 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 0.987 0.975 – 0.999 0.0312 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.994 0.966 – 1.02 0.706 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 0.991 0.972 – 1.01 0.34 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 0.979 0.963 – 0.995 0.011 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 0.988 0.973 – 1 0.103 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.938 0.867 – 1.02 0.112 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.991 0.974 – 1.01 0.275 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.01 0.954 – 1.07 0.693 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 0.974 0.928 – 1.02 0.295 1823 18228 all phecode
414.2 ASCVD Circulatory System 0.932 0.73 – 1.19 0.571 72 719 all phecode
415 Pulmonary heart disease Circulatory System 1.01 0.982 – 1.04 0.438 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.07 0.851 – 1.34 0.576 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.07 0.984 – 1.16 0.112 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.06 0.959 – 1.16 0.267 448 4475 all phecode
416 Cardiomegaly Circulatory System 0.994 0.956 – 1.03 0.777 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 1 0.99 – 1.01 0.677 28599 270106 all phecode
418.1 Precordial pain Circulatory System 1 0.971 – 1.04 0.777 3551 35541 all phecode
420 Carditis Circulatory System 1.02 0.979 – 1.07 0.309 2106 21053 all phecode
420.1 Myocarditis Circulatory System 1.03 0.862 – 1.24 0.716 127 1267 all phecode
420.2 Pericarditis Circulatory System 1.05 0.994 – 1.11 0.0806 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 1.05 0.92 – 1.2 0.466 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 1.02 0.847 – 1.24 0.807 113 1129 all phecode
420.3 Endocarditis Circulatory System 0.982 0.908 – 1.06 0.645 719 7194 all phecode
425 Cardiomyopathy Circulatory System 0.984 0.929 – 1.04 0.589 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.974 0.918 – 1.03 0.382 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.888 0.74 – 1.07 0.205 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1 0.851 – 1.18 0.991 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 1.26 0.984 – 1.61 0.0676 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 0.974 0.95 – 0.998 0.0349 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 0.949 0.907 – 0.993 0.0239 2114 21162 all phecode
426.21 First degree AV block Circulatory System 0.954 0.893 – 1.02 0.166 986 9867 all phecode
426.23 Second degree AV block Circulatory System 0.994 0.901 – 1.1 0.903 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 0.952 0.874 – 1.04 0.26 587 5868 all phecode
426.25 Other heart block Circulatory System 1.04 0.866 – 1.24 0.688 131 1318 all phecode
426.3 Bundle branch block Circulatory System 0.988 0.954 – 1.02 0.508 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 1 0.953 – 1.06 0.858 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 0.974 0.927 – 1.02 0.297 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.918 0.801 – 1.05 0.217 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.56 1.21 – 2.02 0.000614 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.968 0.928 – 1.01 0.129 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.965 0.924 – 1.01 0.114 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 0.989 0.976 – 1 0.0996 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1 0.969 – 1.04 0.788 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.994 0.952 – 1.04 0.769 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.03 0.96 – 1.1 0.444 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 0.991 0.974 – 1.01 0.31 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.985 0.95 – 1.02 0.417 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.987 0.93 – 1.05 0.668 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.922 0.824 – 1.03 0.155 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 1.01 0.943 – 1.07 0.857 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.988 0.925 – 1.06 0.718 952 9541 all phecode
427.6 Premature beats Circulatory System 1.03 0.941 – 1.12 0.542 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 0.919 0.758 – 1.12 0.394 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 0.983 0.941 – 1.03 0.45 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.06 0.956 – 1.16 0.286 402 4029 all phecode
427.9 Palpitations Circulatory System 0.999 0.966 – 1.03 0.938 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.03 0.998 – 1.05 0.073 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.03 0.981 – 1.07 0.255 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 1.02 0.992 – 1.05 0.151 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1 0.929 – 1.08 0.928 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 0.853 0.655 – 1.11 0.238 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.963 0.879 – 1.06 0.423 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.14 0.987 – 1.31 0.0762 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 1.04 0.995 – 1.09 0.0785 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.08 1 – 1.16 0.0375 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1.02 0.947 – 1.1 0.603 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 1.02 0.903 – 1.15 0.74 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 0.996 0.974 – 1.02 0.713 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.998 0.94 – 1.06 0.937 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.03 0.901 – 1.18 0.641 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.986 0.955 – 1.02 0.366 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.977 0.929 – 1.03 0.357 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 0.988 0.951 – 1.03 0.541 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 0.994 0.951 – 1.04 0.792 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 0.989 0.89 – 1.1 0.837 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.988 0.932 – 1.05 0.673 1279 12783 all phecode
440 Atherosclerosis Circulatory System 0.983 0.929 – 1.04 0.537 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.976 0.799 – 1.19 0.814 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.98 0.911 – 1.05 0.585 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 0.973 0.861 – 1.1 0.667 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 0.943 0.867 – 1.03 0.174 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.87 0.764 – 0.99 0.0341 283 2827 all phecode
442 Other aneurysm Circulatory System 1.01 0.966 – 1.06 0.605 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 1 0.951 – 1.06 0.887 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.03 0.961 – 1.1 0.425 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.11 0.916 – 1.35 0.285 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.04 0.895 – 1.21 0.598 169 1696 all phecode
442.4 Arterial dissection Circulatory System 1.41 1.1 – 1.8 0.00664 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 0.962 0.834 – 1.11 0.591 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 1.01 0.973 – 1.04 0.762 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 1.04 0.975 – 1.1 0.262 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.943 0.847 – 1.05 0.28 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1 0.971 – 1.04 0.804 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.993 0.954 – 1.03 0.75 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 0.988 0.924 – 1.06 0.735 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.01 0.926 – 1.1 0.844 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1 0.934 – 1.08 0.919 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 1.1 0.952 – 1.26 0.199 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 1.01 0.913 – 1.12 0.802 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 0.972 0.848 – 1.11 0.682 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 0.945 0.892 – 1 0.0528 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 0.992 0.925 – 1.06 0.821 868 8712 all phecode
448 Disease of capillaries Circulatory System 0.966 0.812 – 1.15 0.693 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.05 0.968 – 1.13 0.254 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.01 0.975 – 1.04 0.65 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.02 0.983 – 1.05 0.35 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 0.979 0.897 – 1.07 0.636 564 5645 all phecode
454 Varicose veins Circulatory System 1 0.983 – 1.02 0.813 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1 0.982 – 1.02 0.919 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.899 0.826 – 0.979 0.0141 624 6325 all phecode
455 Hemorrhoids Circulatory System 1 0.987 – 1.01 0.986 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.944 0.811 – 1.1 0.453 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.07 0.865 – 1.31 0.553 97 967 all phecode
458 Hypotension Circulatory System 1.02 0.995 – 1.05 0.108 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 1 0.948 – 1.06 0.939 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.02 0.897 – 1.17 0.719 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 1.02 0.985 – 1.06 0.279 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 0.997 0.981 – 1.01 0.736 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 1.07 0.904 – 1.26 0.446 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 0.997 0.981 – 1.01 0.73 16103 159422 all phecode
464 Acute sinusitis Respiratory 1.02 0.883 – 1.18 0.777 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.984 0.942 – 1.03 0.452 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 1 0.935 – 1.08 0.894 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.995 0.851 – 1.16 0.948 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.04 1.01 – 1.07 0.0148 4654 46553 all phecode
471 Nasal polyps Respiratory 1.02 0.981 – 1.05 0.373 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.06 0.992 – 1.13 0.0847 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 0.993 0.953 – 1.03 0.72 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 0.913 0.743 – 1.12 0.385 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.04 0.914 – 1.17 0.585 264 2647 all phecode
473.4 Voice disturbance Respiratory 0.979 0.92 – 1.04 0.519 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 1.01 0.958 – 1.06 0.811 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 1.08 0.989 – 1.17 0.0867 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.959 0.901 – 1.02 0.191 1122 11199 all phecode
475 Chronic sinusitis Respiratory 0.988 0.948 – 1.03 0.546 2589 25882 all phecode
476 Allergic rhinitis Respiratory 0.971 0.91 – 1.04 0.376 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 0.971 0.931 – 1.01 0.163 2447 24452 all phecode
478 Throat pain Respiratory 1.08 0.974 – 1.2 0.146 377 3789 all phecode
479 Other upper respiratory disease Respiratory 1.02 0.984 – 1.05 0.33 4074 40737 all phecode
480 Pneumonia Respiratory 1.01 0.986 – 1.03 0.572 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 1.01 0.985 – 1.04 0.442 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.01 0.979 – 1.03 0.664 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.01 0.823 – 1.24 0.911 93 929 all phecode
480.2 Viral pneumonia Respiratory 0.835 0.646 – 1.08 0.168 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.01 0.826 – 1.24 0.923 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.04 0.966 – 1.12 0.305 794 7951 all phecode
481 Influenza Respiratory 0.985 0.879 – 1.1 0.801 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.04 0.897 – 1.2 0.61 193 1930 all phecode
495 Asthma Respiratory 1 0.988 – 1.01 0.939 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 0.894 0.782 – 1.02 0.103 250 2510 all phecode
496 Chronic airway obstruction Respiratory 0.99 0.97 – 1.01 0.326 10424 101546 all phecode
496.1 Emphysema Respiratory 0.983 0.936 – 1.03 0.499 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 0.979 0.943 – 1.02 0.28 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 0.978 0.94 – 1.02 0.272 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 0.987 0.941 – 1.03 0.58 1885 18859 all phecode
497 Bronchitis Respiratory 0.935 0.859 – 1.02 0.124 626 6267 all phecode
500 Lung disease due to external agents Respiratory 0.986 0.892 – 1.09 0.781 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.937 0.745 – 1.18 0.575 79 784 all phecode
500.2 Pneumoconiosis Respiratory 0.963 0.844 – 1.1 0.573 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 0.992 0.915 – 1.08 0.846 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.995 0.93 – 1.07 0.895 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 0.869 0.79 – 0.956 0.00382 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.01 0.9 – 1.13 0.875 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 0.97 0.747 – 1.26 0.818 61 610 all phecode
506 Empyema and pneumothorax Respiratory 1.01 0.948 – 1.07 0.82 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 1.01 0.983 – 1.03 0.539 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.984 0.939 – 1.03 0.494 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.01 0.972 – 1.05 0.559 2599 26031 all phecode
509.1 Respiratory failure Respiratory 1.03 0.988 – 1.08 0.149 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 1.03 0.98 – 1.08 0.252 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 1.08 0.917 – 1.27 0.354 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.922 0.829 – 1.02 0.133 386 3863 all phecode
510 Other diseases of lung Respiratory 1.07 0.993 – 1.15 0.0752 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 1.03 1 – 1.05 0.0182 9031 90349 all phecode
512.1 Wheezing Respiratory 0.99 0.86 – 1.14 0.894 220 2196 all phecode
512.2 Painful respiration Respiratory 1.12 0.971 – 1.29 0.121 207 2075 all phecode
512.7 Shortness of breath Respiratory 1.03 0.999 – 1.05 0.0595 5842 58498 all phecode
512.8 Cough Respiratory 1.03 0.996 – 1.07 0.0772 2866 28642 all phecode
512.9 Other dyspnea Respiratory 1 0.938 – 1.07 0.919 914 9124 all phecode
513 Respiratory abnormalities Respiratory 0.989 0.909 – 1.08 0.794 611 6112 all phecode
513.3 Hypoventilation Respiratory 1.05 0.833 – 1.32 0.684 83 830 all phecode
513.4 Hyperventilation Respiratory 0.955 0.842 – 1.08 0.473 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 1.03 0.872 – 1.21 0.734 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 1.02 0.978 – 1.06 0.36 2465 24673 all phecode
516 Abnormal sputum Respiratory 1.01 0.968 – 1.06 0.608 2132 21335 all phecode
516.1 Hemoptysis Respiratory 1.01 0.97 – 1.06 0.528 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.994 0.973 – 1.01 0.548 9366 93681 all phecode
519.2 Respiratory complications Respiratory 1.07 0.959 – 1.2 0.22 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.989 0.968 – 1.01 0.319 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.03 0.912 – 1.16 0.662 303 3049 all phecode
520 Disorders of tooth development Digestive 1 0.956 – 1.05 1 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.859 0.642 – 1.15 0.307 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 0.98 0.94 – 1.02 0.358 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 1.01 0.971 – 1.05 0.686 3016 30245 all phecode
521.1 Dental caries Digestive 1.01 0.971 – 1.05 0.665 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.02 0.969 – 1.07 0.487 1774 17750 all phecode
522.5 Periapical abscess Digestive 1.02 0.959 – 1.08 0.551 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 1.01 0.96 – 1.06 0.72 1681 16812 all phecode
523.1 Gingivitis Digestive 1.01 0.841 – 1.21 0.915 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.03 0.973 – 1.09 0.296 1165 11650 all phecode
523.31 Acute periodontitis Digestive 1.01 0.93 – 1.09 0.865 666 6667 all phecode
523.32 Chronic periodontitis Digestive 1.04 0.953 – 1.13 0.395 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.06 0.951 – 1.19 0.283 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.05 0.936 – 1.18 0.397 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.96 0.922 – 1 0.0484 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.17 0.934 – 1.47 0.172 72 720 all phecode
526 Diseases of the jaws Digestive 0.991 0.926 – 1.06 0.787 928 9279 all phecode
526.1 Cysts of the jaws Digestive 0.91 0.811 – 1.02 0.111 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.12 0.877 – 1.42 0.374 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 1.01 0.887 – 1.15 0.858 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.02 0.896 – 1.17 0.739 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 0.978 0.8 – 1.2 0.832 110 1098 all phecode
526.9 Jaw disease NOS Digestive 1.01 0.883 – 1.16 0.861 233 2329 all phecode
527 Diseases of the salivary glands Digestive 0.997 0.921 – 1.08 0.948 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.11 0.892 – 1.39 0.341 84 838 all phecode
527.2 Sialoadenitis Digestive 0.968 0.867 – 1.08 0.555 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 0.952 0.729 – 1.24 0.719 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 0.97 0.803 – 1.17 0.748 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.993 0.961 – 1.03 0.688 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 1.03 0.936 – 1.13 0.562 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.02 0.922 – 1.13 0.685 389 3884 all phecode
528.12 Oral aphthae Digestive 1.1 0.881 – 1.37 0.407 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.01 0.868 – 1.18 0.879 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 0.874 0.721 – 1.06 0.167 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 0.788 0.629 – 0.986 0.0376 94 940 all phecode
528.5 Diseases of lips Digestive 1.03 0.954 – 1.12 0.436 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 0.855 0.757 – 0.966 0.012 308 3079 all phecode
528.7 Sialolithiasis Digestive 0.942 0.838 – 1.06 0.31 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 1.01 0.957 – 1.07 0.631 1232 12312 all phecode
529.1 Glossitis Digestive 1.12 0.995 – 1.25 0.0617 299 2986 all phecode
530 Diseases of esophagus Digestive 1 0.99 – 1.01 0.818 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.01 0.995 – 1.02 0.283 31253 272429 all phecode
530.11 GERD Digestive 1.01 0.995 – 1.02 0.223 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 1.02 0.994 – 1.05 0.125 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 1.01 0.995 – 1.04 0.153 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.948 0.901 – 0.997 0.0393 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 0.989 0.943 – 1.04 0.656 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 0.966 0.891 – 1.05 0.412 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.955 0.813 – 1.12 0.579 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.945 0.843 – 1.06 0.327 341 3416 all phecode
530.9 Heartburn Digestive 1 0.956 – 1.05 0.989 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.01 0.984 – 1.03 0.506 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.05 0.97 – 1.14 0.22 637 6374 all phecode
531.2 Gastric ulcer Digestive 0.992 0.96 – 1.02 0.62 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 1.01 0.977 – 1.05 0.462 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 0.965 0.873 – 1.07 0.48 427 4268 all phecode
532 Dysphagia Digestive 0.987 0.962 – 1.01 0.323 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 0.99 0.978 – 1 0.109 28078 261548 all phecode
535.1 Acute gastritis Digestive 0.984 0.927 – 1.04 0.585 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 0.981 0.883 – 1.09 0.727 370 3687 all phecode
535.6 Duodenitis Digestive 0.985 0.962 – 1.01 0.205 7592 75928 all phecode
535.8 Other specified gastritis Digestive 0.994 0.972 – 1.02 0.619 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.02 0.845 – 1.23 0.828 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.01 0.886 – 1.14 0.932 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 1.01 0.972 – 1.04 0.705 3391 33907 all phecode
540 Appendiceal conditions Digestive 0.994 0.959 – 1.03 0.76 3088 30890 all phecode
540.1 Appendicitis Digestive 0.991 0.954 – 1.03 0.626 2895 28963 all phecode
540.11 Acute appendicitis Digestive 0.988 0.949 – 1.03 0.538 2601 26019 all phecode
550 Abdominal hernia Digestive 0.996 0.987 – 1.01 0.486 45429 282640 all phecode
550.1 Inguinal hernia Digestive 0.992 0.976 – 1.01 0.352 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 1 0.988 – 1.01 0.916 26494 238953 all phecode
550.3 Femoral hernia Digestive 0.978 0.903 – 1.06 0.586 651 6504 all phecode
550.4 Umbilical hernia Digestive 1.03 0.992 – 1.06 0.143 3705 37072 all phecode
550.5 Ventral hernia Digestive 0.991 0.957 – 1.03 0.626 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 0.99 0.96 – 1.02 0.519 4444 44442 all phecode
555.1 Regional enteritis Digestive 0.998 0.95 – 1.05 0.93 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 0.977 0.942 – 1.01 0.218 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 0.981 0.898 – 1.07 0.668 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 1.07 1.01 – 1.14 0.033 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 1.03 0.956 – 1.12 0.403 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.964 0.854 – 1.09 0.548 299 2987 all phecode
557.1 Celiac disease Digestive 0.945 0.9 – 0.992 0.0235 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 1.01 0.989 – 1.02 0.511 15492 155105 all phecode
559 Ileostomy status Digestive 0.966 0.917 – 1.02 0.18 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.01 0.979 – 1.05 0.49 3936 39337 all phecode
560.1 Paralytic ileus Digestive 1.04 0.95 – 1.13 0.41 523 5231 all phecode
560.2 Impaction of intestine Digestive 0.996 0.879 – 1.13 0.95 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.963 0.896 – 1.03 0.304 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 0.999 0.964 – 1.03 0.936 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 0.997 0.981 – 1.01 0.694 15772 157686 all phecode
561.1 Diarrhea Digestive 1 0.913 – 1.1 0.929 466 4653 all phecode
561.2 Flatulence Digestive 1.02 0.966 – 1.07 0.559 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 0.996 0.984 – 1.01 0.576 26714 211692 all phecode
562.1 Diverticulosis Digestive 0.996 0.984 – 1.01 0.558 26672 211642 all phecode
563 Constipation Digestive 0.993 0.973 – 1.01 0.502 10314 103140 all phecode
564 Functional digestive disorders Digestive 0.996 0.983 – 1.01 0.611 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.01 0.982 – 1.04 0.505 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.01 0.963 – 1.07 0.604 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 0.99 0.974 – 1.01 0.25 15186 151648 all phecode
565 Anal and rectal conditions Digestive 0.992 0.976 – 1.01 0.381 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 0.997 0.974 – 1.02 0.834 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1 0.938 – 1.07 0.939 929 9293 all phecode
568 Other disorders of peritoneum Digestive 1.03 0.998 – 1.07 0.0666 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.03 0.992 – 1.07 0.123 3101 30987 all phecode
569 Other disorders of intestine Digestive 1.01 0.978 – 1.04 0.577 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.96 0.809 – 1.14 0.643 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 1.06 0.964 – 1.16 0.244 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 0.997 0.96 – 1.04 0.889 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.02 0.969 – 1.07 0.47 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.905 0.744 – 1.1 0.323 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 1 0.883 – 1.14 0.959 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.979 0.916 – 1.05 0.529 976 9804 all phecode
571.81 Portal hypertension Digestive 0.956 0.874 – 1.05 0.325 528 5285 all phecode
572 Ascites (non malignant) Digestive 1.05 0.996 – 1.1 0.0704 1544 15454 all phecode
573 Other disorders of liver Digestive 1.03 0.979 – 1.09 0.248 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 0.915 0.737 – 1.14 0.425 96 960 all phecode
573.3 Hepatomegaly Digestive 0.949 0.843 – 1.07 0.386 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 0.942 0.879 – 1.01 0.0895 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 0.991 0.957 – 1.03 0.614 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 0.944 0.82 – 1.09 0.422 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 0.986 0.97 – 1 0.0909 15607 156123 all phecode
574.1 Cholelithiasis Digestive 0.984 0.967 – 1 0.0741 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.946 0.896 – 0.998 0.0424 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1 0.975 – 1.03 0.835 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 1.02 0.983 – 1.06 0.267 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.963 0.926 – 1 0.0656 2748 27523 all phecode
575 Other biliary tract disease Digestive 0.998 0.965 – 1.03 0.887 3867 38724 all phecode
575.1 Cholangitis Digestive 1 0.916 – 1.1 0.921 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 0.935 0.867 – 1.01 0.0835 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 0.967 0.878 – 1.07 0.497 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 1 0.951 – 1.06 0.866 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 0.992 0.931 – 1.06 0.817 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.08 0.966 – 1.2 0.183 348 3488 all phecode
577 Diseases of pancreas Digestive 1.02 0.976 – 1.06 0.448 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 1.02 0.978 – 1.07 0.315 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 0.924 0.842 – 1.01 0.0924 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.99 0.889 – 1.1 0.847 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 1 0.99 – 1.02 0.544 20626 206278 all phecode
578.1 Hematemesis Digestive 0.957 0.913 – 1 0.0654 1958 19564 all phecode
578.2 Blood in stool Digestive 0.986 0.947 – 1.03 0.496 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.01 0.997 – 1.03 0.112 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.994 0.967 – 1.02 0.698 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1 0.951 – 1.06 0.946 1548 15498 all phecode
579.2 Splenomegaly Digestive 0.958 0.866 – 1.06 0.4 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.984 0.935 – 1.04 0.55 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.02 0.971 – 1.08 0.386 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 1.02 0.957 – 1.09 0.557 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.01 0.807 – 1.27 0.905 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.796 0.662 – 0.958 0.0156 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.04 0.972 – 1.12 0.249 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.08 0.986 – 1.19 0.0979 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.968 0.849 – 1.11 0.635 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.988 0.868 – 1.12 0.849 253 2529 all phecode
585 Renal failure Genitourinary 1.01 0.985 – 1.03 0.463 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 1.01 0.984 – 1.05 0.352 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 1.01 0.956 – 1.06 0.758 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1 0.964 – 1.04 0.888 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 0.997 0.91 – 1.09 0.957 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 0.997 0.962 – 1.03 0.863 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.91 0.788 – 1.05 0.203 208 2089 all phecode
586.11 Small kidney Genitourinary 0.944 0.808 – 1.1 0.47 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.01 0.955 – 1.07 0.698 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.04 0.835 – 1.3 0.71 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.01 0.947 – 1.08 0.708 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 0.977 0.876 – 1.09 0.672 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.04 0.844 – 1.29 0.686 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.01 0.84 – 1.22 0.902 116 1158 all phecode
590 Pyelonephritis Genitourinary 1.02 0.96 – 1.07 0.584 1328 13285 all phecode
591 Urinary tract infection Genitourinary 0.993 0.975 – 1.01 0.439 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 0.996 0.96 – 1.03 0.854 2966 29661 all phecode
592.1 Cystitis Genitourinary 0.989 0.952 – 1.03 0.577 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 0.951 0.799 – 1.13 0.572 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 0.963 0.898 – 1.03 0.285 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 1.01 0.889 – 1.15 0.863 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.11 0.949 – 1.29 0.197 165 1662 all phecode
593 Hematuria Genitourinary 0.985 0.969 – 1 0.0629 16068 160204 all phecode
594 Urinary calculus Genitourinary 0.983 0.958 – 1.01 0.185 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 1.02 0.981 – 1.05 0.37 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 0.911 0.844 – 0.983 0.0161 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 1 0.96 – 1.04 0.948 2401 24024 all phecode
594.8 Renal colic Genitourinary 0.964 0.921 – 1.01 0.117 2050 20500 all phecode
595 Hydronephrosis Genitourinary 0.978 0.933 – 1.02 0.351 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 1 0.982 – 1.02 0.822 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 0.963 0.919 – 1.01 0.117 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 0.998 0.949 – 1.05 0.93 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.01 0.976 – 1.04 0.598 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1 0.966 – 1.04 0.956 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 1.13 0.912 – 1.41 0.257 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 0.97 0.936 – 1 0.0848 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.941 0.836 – 1.06 0.315 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.992 0.977 – 1.01 0.304 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 0.906 0.768 – 1.07 0.241 166 1670 all phecode
599.2 Retention of urine Genitourinary 1.02 0.994 – 1.04 0.143 6718 67168 all phecode
599.3 Dysuria Genitourinary 0.984 0.926 – 1.05 0.605 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 0.991 0.969 – 1.01 0.397 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1.01 0.976 – 1.04 0.621 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 0.931 0.759 – 1.14 0.49 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 0.94 0.727 – 1.21 0.636 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 1.03 0.981 – 1.08 0.24 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 1 0.981 – 1.02 0.972 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.982 0.939 – 1.03 0.438 2081 20818 all phecode
601.1 Prostatitis Genitourinary 1.02 0.964 – 1.07 0.571 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 1.02 0.897 – 1.17 0.742 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 1.01 0.947 – 1.09 0.696 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 1.12 0.869 – 1.45 0.377 59 588 all phecode
601.4 Balanoposthitis Genitourinary 0.935 0.829 – 1.06 0.28 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.936 0.829 – 1.06 0.283 303 3019 all phecode
602 Other disorders of prostate Genitourinary 1 0.946 – 1.06 0.988 1341 13408 all phecode
603 Other disorders of testis Genitourinary 0.992 0.949 – 1.04 0.736 2150 21512 all phecode
603.1 Hydrocele Genitourinary 0.983 0.929 – 1.04 0.542 1339 13402 all phecode
604 Disorders of penis Genitourinary 0.995 0.96 – 1.03 0.799 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.975 0.937 – 1.01 0.207 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 1.07 0.945 – 1.2 0.3 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 1.02 0.977 – 1.06 0.44 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.963 0.839 – 1.11 0.594 214 2138 all phecode
609.1 Infertility, male Genitourinary 1.04 0.812 – 1.33 0.754 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.978 0.838 – 1.14 0.78 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 0.998 0.958 – 1.04 0.941 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 1.01 0.941 – 1.08 0.86 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.1 0.981 – 1.23 0.104 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 0.972 0.862 – 1.1 0.643 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.98 0.927 – 1.04 0.479 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.983 0.908 – 1.06 0.666 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.01 0.962 – 1.07 0.631 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 1.05 0.805 – 1.38 0.7 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 1.02 0.965 – 1.07 0.537 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.977 0.912 – 1.05 0.517 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.972 0.905 – 1.04 0.429 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 1.14 0.906 – 1.44 0.26 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 0.959 0.911 – 1.01 0.104 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 0.94 0.87 – 1.02 0.121 720 7210 all phecode
613.5 Mastodynia Genitourinary 0.755 0.585 – 0.973 0.0298 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 1.01 0.93 – 1.09 0.892 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 1.03 0.919 – 1.15 0.644 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 0.979 0.85 – 1.13 0.765 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.978 0.952 – 1.01 0.113 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.968 0.929 – 1.01 0.122 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.994 0.926 – 1.07 0.869 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.977 0.752 – 1.27 0.86 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.954 0.863 – 1.05 0.356 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.05 0.945 – 1.18 0.342 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.991 0.875 – 1.12 0.891 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.981 0.942 – 1.02 0.351 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.99 0.936 – 1.05 0.731 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.03 0.932 – 1.14 0.579 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.956 0.887 – 1.03 0.241 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.973 0.861 – 1.1 0.661 274 2737 all phecode
615 Endometriosis Genitourinary 0.988 0.956 – 1.02 0.453 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.08 0.961 – 1.21 0.2 304 3037 all phecode
618 Genital prolapse Genitourinary 1.01 0.993 – 1.03 0.212 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1.01 0.988 – 1.04 0.345 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.01 0.985 – 1.04 0.389 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.02 0.932 – 1.12 0.668 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.986 0.91 – 1.07 0.72 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 1 0.978 – 1.02 0.979 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.01 0.936 – 1.09 0.812 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 0.978 0.943 – 1.01 0.227 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.02 0.986 – 1.06 0.219 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.03 0.978 – 1.08 0.277 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.969 0.915 – 1.02 0.267 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 1.05 0.832 – 1.32 0.686 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 0.97 0.911 – 1.03 0.331 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 1 0.981 – 1.02 0.906 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 1 0.977 – 1.02 0.973 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 1 0.966 – 1.04 0.97 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.01 0.95 – 1.06 0.851 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 0.947 0.879 – 1.02 0.144 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.936 0.819 – 1.07 0.335 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.965 0.872 – 1.07 0.487 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 0.987 0.961 – 1.01 0.334 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1 0.965 – 1.04 0.867 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 1 0.944 – 1.07 0.921 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1 0.988 – 1.02 0.603 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.01 0.988 – 1.02 0.549 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 0.918 0.749 – 1.12 0.407 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.01 0.987 – 1.03 0.456 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 0.984 0.939 – 1.03 0.49 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 1.01 0.974 – 1.04 0.698 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 0.952 0.906 – 1 0.054 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 1.14 0.975 – 1.32 0.103 159 1587 all phecode
626.8 Infertility, female Genitourinary 0.986 0.933 – 1.04 0.625 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.01 0.99 – 1.03 0.309 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 1.01 0.987 – 1.03 0.421 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 1.12 0.966 – 1.29 0.137 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.999 0.939 – 1.06 0.982 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 1.07 0.956 – 1.2 0.232 310 3097 all phecode
628 Ovarian cyst Genitourinary 0.986 0.957 – 1.02 0.373 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.994 0.966 – 1.02 0.708 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.03 0.972 – 1.1 0.301 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.02 0.913 – 1.14 0.713 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1 0.957 – 1.05 0.883 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.01 0.942 – 1.09 0.766 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.997 0.941 – 1.06 0.921 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.01 0.972 – 1.06 0.51 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 1 0.921 – 1.09 0.982 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.02 0.958 – 1.08 0.547 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 0.904 0.695 – 1.17 0.448 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.977 0.918 – 1.04 0.473 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.07 0.954 – 1.2 0.245 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.823 0.71 – 0.955 0.0103 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.869 0.732 – 1.03 0.106 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.999 0.943 – 1.06 0.97 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.992 0.95 – 1.04 0.727 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.03 0.816 – 1.31 0.79 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.09 0.971 – 1.23 0.138 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.98 0.811 – 1.18 0.833 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.01 0.868 – 1.17 0.903 193 1922 all phecode
650 Normal delivery Pregnancy Complications 1.02 0.968 – 1.06 0.534 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 1.01 0.905 – 1.13 0.845 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.981 0.933 – 1.03 0.456 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1 0.946 – 1.06 1 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.29 1.02 – 1.62 0.0312 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.982 0.95 – 1.01 0.262 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.01 0.833 – 1.23 0.909 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.964 0.922 – 1.01 0.108 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.992 0.906 – 1.09 0.862 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.985 0.956 – 1.02 0.336 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1 0.963 – 1.05 0.862 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.789 0.66 – 0.944 0.00953 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.979 0.863 – 1.11 0.745 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.961 0.739 – 1.25 0.767 63 624 all phecode
679 Complications of in utero procedures Dermatologic 1.13 0.854 – 1.49 0.392 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.01 0.984 – 1.03 0.54 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.919 0.841 – 1 0.0634 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.02 0.937 – 1.12 0.599 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.01 0.985 – 1.04 0.382 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.02 0.988 – 1.04 0.275 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.01 0.986 – 1.04 0.344 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.07 0.987 – 1.16 0.0985 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.1 1.04 – 1.16 0.000674 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.01 0.971 – 1.06 0.528 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 0.997 0.916 – 1.08 0.947 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 0.896 0.802 – 1 0.0535 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 1.1 1.01 – 1.2 0.0273 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.992 0.949 – 1.04 0.713 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.13 1 – 1.27 0.0493 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 1.08 0.884 – 1.31 0.464 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.02 0.985 – 1.06 0.247 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.973 0.947 – 1 0.0481 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.852 0.664 – 1.09 0.206 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.807 0.596 – 1.09 0.166 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 0.827 0.678 – 1.01 0.0598 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.93 0.869 – 0.995 0.0343 986 9854 all phecode
694.1 Vitiligo Dermatologic 0.96 0.73 – 1.26 0.773 60 599 all phecode
694.2 Other dyschromia Dermatologic 0.929 0.861 – 1 0.0572 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 0.935 0.771 – 1.13 0.493 117 1170 all phecode
695 Erythematous conditions Dermatologic 1 0.961 – 1.05 0.926 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 1.13 0.938 – 1.35 0.201 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 1.08 0.909 – 1.27 0.395 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 1.09 0.842 – 1.41 0.516 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.15 0.912 – 1.44 0.243 73 727 all phecode
695.3 Rosacea Dermatologic 1.08 0.964 – 1.21 0.186 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 0.966 0.87 – 1.07 0.51 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.851 0.703 – 1.03 0.0967 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 0.987 0.881 – 1.1 0.814 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 1 0.931 – 1.08 0.945 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 0.944 0.826 – 1.08 0.395 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 0.838 0.657 – 1.07 0.156 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 0.995 0.904 – 1.1 0.925 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 0.955 0.914 – 0.998 0.041 2252 22509 all phecode
696.4 Psoriasis Dermatologic 0.957 0.915 – 1 0.0541 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 0.975 0.927 – 1.03 0.333 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 0.947 0.875 – 1.02 0.175 706 7052 all phecode
697 Sarcoidosis Dermatologic 1.04 0.952 – 1.13 0.389 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 0.989 0.919 – 1.06 0.758 782 7814 all phecode
700 Corns and callosities Dermatologic 0.965 0.854 – 1.09 0.564 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1 0.972 – 1.03 0.898 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 1.06 0.851 – 1.31 0.614 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.02 0.974 – 1.06 0.473 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.12 0.865 – 1.45 0.387 61 610 all phecode
701.4 Keloid scar Dermatologic 0.929 0.807 – 1.07 0.31 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 1.02 0.924 – 1.12 0.723 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 0.912 0.742 – 1.12 0.38 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.01 0.981 – 1.04 0.561 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 1 0.963 – 1.04 0.892 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 1.01 0.976 – 1.05 0.518 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 1 0.9 – 1.12 0.945 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 1.06 0.995 – 1.13 0.0693 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 1.03 0.997 – 1.05 0.0846 5267 52727 all phecode
704.1 Alopecia Dermatologic 1 0.835 – 1.21 0.968 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.16 0.938 – 1.43 0.171 76 759 all phecode
705 Disorders of sweat glands Dermatologic 0.966 0.843 – 1.11 0.62 228 2287 all phecode
705.3 Hidradenitis Dermatologic 0.943 0.811 – 1.1 0.444 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 1.11 1.02 – 1.2 0.0138 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 1.03 1.01 – 1.05 0.0137 8317 83195 all phecode
706.1 Acne Dermatologic 1.19 0.957 – 1.49 0.116 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 1.02 0.999 – 1.04 0.0599 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 1.03 0.985 – 1.08 0.193 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 1.04 0.975 – 1.12 0.22 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 1 0.969 – 1.04 0.853 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 1.02 0.928 – 1.11 0.734 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 0.966 0.827 – 1.13 0.66 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1 0.788 – 1.28 0.982 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.995 0.957 – 1.04 0.819 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.03 0.948 – 1.12 0.481 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 1.02 0.931 – 1.11 0.723 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.01 0.87 – 1.17 0.904 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.02 0.922 – 1.13 0.676 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.04 0.945 – 1.15 0.406 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.04 0.934 – 1.17 0.444 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.24 0.999 – 1.55 0.0509 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.11 0.944 – 1.31 0.2 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.11 0.872 – 1.42 0.389 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 0.992 0.963 – 1.02 0.61 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.989 0.958 – 1.02 0.472 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.967 0.919 – 1.02 0.197 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.965 0.795 – 1.17 0.716 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.997 0.919 – 1.08 0.949 618 6177 all phecode
716 Other arthropathies Musculoskeletal 1.01 0.997 – 1.02 0.181 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.02 0.983 – 1.05 0.312 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.01 0.989 – 1.02 0.546 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.01 0.995 – 1.02 0.322 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.997 0.939 – 1.06 0.931 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 1.01 0.977 – 1.05 0.547 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1 0.981 – 1.03 0.755 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.01 0.983 – 1.04 0.439 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1 0.861 – 1.16 0.995 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.03 0.927 – 1.15 0.557 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 1.02 1 – 1.05 0.0316 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.989 0.902 – 1.08 0.813 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.03 0.996 – 1.08 0.0792 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1 0.778 – 1.29 0.99 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.04 1.01 – 1.07 0.0171 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 1.05 0.96 – 1.15 0.288 517 5173 all phecode
723.1 Torticollis Musculoskeletal 1.02 0.843 – 1.23 0.837 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.03 0.98 – 1.07 0.278 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 0.947 0.855 – 1.05 0.303 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 0.944 0.852 – 1.05 0.276 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.16 0.904 – 1.49 0.244 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.04 0.988 – 1.09 0.138 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.999 0.982 – 1.02 0.883 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 1 0.98 – 1.02 0.917 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 0.98 0.876 – 1.1 0.731 334 3336 all phecode
726.3 Bursitis Musculoskeletal 0.977 0.911 – 1.05 0.516 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.01 0.985 – 1.03 0.486 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.972 0.935 – 1.01 0.168 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 1.16 0.958 – 1.4 0.129 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.01 0.97 – 1.04 0.74 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 1.08 0.992 – 1.17 0.0781 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.989 0.886 – 1.1 0.843 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.05 0.882 – 1.24 0.595 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.02 0.984 – 1.05 0.318 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.06 0.962 – 1.17 0.238 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 1.02 0.985 – 1.05 0.299 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.01 0.98 – 1.05 0.43 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.01 0.987 – 1.04 0.306 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1 0.939 – 1.07 0.941 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 0.991 0.807 – 1.22 0.931 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.965 0.851 – 1.09 0.573 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.965 0.849 – 1.1 0.586 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 0.944 0.857 – 1.04 0.25 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.888 0.766 – 1.03 0.112 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.05 0.805 – 1.37 0.72 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.01 0.958 – 1.06 0.792 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 1 0.892 – 1.13 0.943 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.02 0.93 – 1.11 0.739 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 0.989 0.831 – 1.18 0.9 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.959 0.903 – 1.02 0.172 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 0.868 0.716 – 1.05 0.151 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 1.01 0.985 – 1.03 0.566 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 1.01 0.871 – 1.16 0.922 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 1.01 0.983 – 1.04 0.441 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.02 0.973 – 1.07 0.413 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 0.994 0.943 – 1.05 0.813 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.01 0.984 – 1.04 0.465 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 1.03 0.98 – 1.08 0.236 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1.02 0.896 – 1.16 0.756 248 2476 all phecode
737 Curvature of spine Musculoskeletal 0.979 0.92 – 1.04 0.493 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.97 0.91 – 1.03 0.343 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1 0.956 – 1.05 0.938 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.97 0.919 – 1.02 0.259 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 0.995 0.907 – 1.09 0.914 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 1.01 0.998 – 1.02 0.102 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.01 0.992 – 1.02 0.337 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1 0.981 – 1.02 0.818 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.985 0.883 – 1.1 0.787 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.958 0.879 – 1.04 0.322 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.02 0.997 – 1.03 0.111 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.03 0.993 – 1.06 0.122 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 1.08 0.878 – 1.32 0.479 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 1.06 0.98 – 1.15 0.139 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 1.04 0.883 – 1.22 0.655 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 1.04 0.987 – 1.1 0.138 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 1.16 0.955 – 1.4 0.138 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 0.75 0.559 – 1.01 0.0559 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.03 0.989 – 1.07 0.16 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 1.05 0.944 – 1.18 0.348 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.863 0.696 – 1.07 0.179 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.11 1.02 – 1.22 0.0219 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 1.02 0.972 – 1.07 0.46 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.01 0.982 – 1.03 0.635 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 1 0.978 – 1.03 0.782 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 1 0.974 – 1.03 0.938 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 0.992 0.908 – 1.08 0.862 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 1.02 0.928 – 1.11 0.732 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.04 0.969 – 1.12 0.28 815 8144 all phecode
745 Pain in joint Musculoskeletal 0.996 0.973 – 1.02 0.723 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.98 0.942 – 1.02 0.312 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.98 0.941 – 1.02 0.324 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.973 0.892 – 1.06 0.533 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.905 0.787 – 1.04 0.159 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.985 0.938 – 1.03 0.539 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.999 0.856 – 1.17 0.986 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.21 0.923 – 1.59 0.165 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.07 0.946 – 1.2 0.295 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.991 0.916 – 1.07 0.812 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.976 0.872 – 1.09 0.671 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.905 0.779 – 1.05 0.194 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.03 0.921 – 1.14 0.636 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.01 0.886 – 1.16 0.856 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.996 0.825 – 1.2 0.967 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.946 0.896 – 0.998 0.0421 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.91 0.84 – 0.987 0.0225 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.943 0.854 – 1.04 0.242 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.875 0.759 – 1.01 0.0645 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.995 0.927 – 1.07 0.892 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 1.03 0.93 – 1.14 0.597 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.01 0.9 – 1.12 0.921 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.937 0.835 – 1.05 0.276 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 1.05 0.918 – 1.19 0.506 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 1.01 0.875 – 1.17 0.883 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.732 0.564 – 0.95 0.0192 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.11 0.922 – 1.33 0.278 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.06 0.839 – 1.34 0.62 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.949 0.782 – 1.15 0.597 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1 0.908 – 1.11 0.937 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.06 0.925 – 1.23 0.385 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.848 0.713 – 1.01 0.0628 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.819 0.66 – 1.02 0.0684 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1 0.923 – 1.09 0.956 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.03 0.818 – 1.29 0.82 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.01 0.919 – 1.11 0.807 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.14 0.972 – 1.35 0.105 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.01 0.786 – 1.31 0.917 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.962 0.837 – 1.1 0.578 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.949 0.774 – 1.16 0.615 96 959 all phecode
760 Back pain Symptoms 1.01 0.991 – 1.03 0.288 11126 111353 all phecode
761 Cervicalgia Symptoms 1.01 0.961 – 1.06 0.726 1791 17901 all phecode
764 Sciatica Symptoms 1.01 0.965 – 1.05 0.764 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.06 0.997 – 1.12 0.0616 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 1.11 1.03 – 1.2 0.0074 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.936 0.873 – 1 0.0671 870 8687 all phecode
771.1 Swelling of limb Symptoms 1.01 0.982 – 1.04 0.449 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 1.06 0.983 – 1.15 0.126 659 6581 all phecode
773 Pain in limb Symptoms 1 0.976 – 1.03 0.879 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 0.955 0.816 – 1.12 0.565 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.06 1.01 – 1.11 0.0124 1870 18715 all phecode
782.3 Edema Symptoms 1.03 0.982 – 1.09 0.215 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 1.07 0.917 – 1.25 0.392 175 1748 all phecode
783 Fever of unknown origin Symptoms 1.01 0.975 – 1.04 0.672 3911 39105 all phecode
785 Abdominal pain Symptoms 1 0.992 – 1.01 0.675 40080 301686 all phecode
788 Syncope and collapse Symptoms 0.982 0.961 – 1 0.0973 9069 90813 all phecode
789 Nausea and vomiting Symptoms 0.999 0.98 – 1.02 0.904 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 1 0.848 – 1.18 0.991 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 0.907 0.718 – 1.15 0.416 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.02 0.991 – 1.04 0.214 6357 63635 all phecode
791 Gangrene Symptoms 1.07 0.987 – 1.17 0.0964 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.946 0.762 – 1.17 0.611 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.05 0.883 – 1.24 0.595 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 0.97 0.889 – 1.06 0.493 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.98 0.813 – 1.18 0.83 120 1198 all phecode
797 Shock Symptoms 1.15 0.985 – 1.35 0.0758 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 1.15 0.947 – 1.39 0.159 102 1020 all phecode
798 Malaise and fatigue Symptoms 1 0.966 – 1.04 0.979 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 1 0.923 – 1.09 0.914 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 1.01 0.985 – 1.03 0.472 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.984 0.938 – 1.03 0.523 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.14 0.979 – 1.32 0.0929 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.07 1.02 – 1.12 0.00305 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 1.04 0.969 – 1.12 0.262 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.02 0.975 – 1.06 0.403 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.04 0.987 – 1.09 0.15 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 1.04 0.961 – 1.12 0.347 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 1.02 1 – 1.05 0.0388 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.04 0.99 – 1.09 0.116 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.02 0.992 – 1.05 0.157 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.04 0.984 – 1.09 0.173 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 1 0.967 – 1.04 0.909 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.997 0.943 – 1.05 0.905 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 0.979 0.909 – 1.05 0.569 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.02 0.959 – 1.07 0.601 1300 12998 all phecode
817 Concussion Injuries & Poisonings 1.02 0.89 – 1.16 0.821 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.07 0.975 – 1.16 0.162 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.03 0.988 – 1.06 0.185 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 1.08 1.03 – 1.13 0.00259 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 0.98 0.937 – 1.03 0.386 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 1.02 0.999 – 1.03 0.058 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.06 0.97 – 1.16 0.2 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 0.982 0.894 – 1.08 0.696 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.01 0.986 – 1.04 0.317 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.05 0.891 – 1.24 0.562 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.02 0.931 – 1.12 0.663 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.986 0.94 – 1.04 0.579 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.982 0.926 – 1.04 0.55 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.963 0.928 – 0.999 0.0458 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.02 0.981 – 1.05 0.362 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 1.28 1.01 – 1.62 0.0441 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.02 0.981 – 1.05 0.381 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.962 0.85 – 1.09 0.546 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 1.05 0.913 – 1.22 0.469 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.02 0.986 – 1.06 0.223 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.01 0.882 – 1.16 0.864 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 0.792 0.612 – 1.03 0.0768 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 1 0.968 – 1.03 0.991 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.06 0.807 – 1.4 0.667 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.02 0.819 – 1.27 0.854 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.06 0.909 – 1.23 0.472 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 1.01 0.919 – 1.11 0.846 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 1.14 1 – 1.31 0.0479 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.1 0.947 – 1.28 0.211 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.09 0.932 – 1.28 0.276 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.03 0.975 – 1.09 0.28 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.02 0.985 – 1.05 0.309 4260 42663 all phecode
916 Contusion Injuries & Poisonings 1.02 0.967 – 1.08 0.458 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.916 0.783 – 1.07 0.277 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.04 0.944 – 1.16 0.399 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.958 0.842 – 1.09 0.511 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.04 0.992 – 1.08 0.105 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.11 0.969 – 1.26 0.137 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.04 0.858 – 1.27 0.661 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.933 0.853 – 1.02 0.125 550 5509 all phecode
947 Urticaria Injuries & Poisonings 0.997 0.896 – 1.11 0.958 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 0.939 0.845 – 1.04 0.247 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.933 0.844 – 1.03 0.181 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.99 0.873 – 1.12 0.881 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.972 0.885 – 1.07 0.546 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 0.941 0.712 – 1.24 0.667 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.814 0.629 – 1.05 0.119 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1 0.989 – 1.02 0.579 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.01 0.989 – 1.02 0.519 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 0.958 0.865 – 1.06 0.41 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.951 0.886 – 1.02 0.165 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.05 0.946 – 1.17 0.352 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.06 0.95 – 1.18 0.304 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.964 0.838 – 1.11 0.604 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.08 0.958 – 1.21 0.215 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.11 0.984 – 1.25 0.0915 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.971 0.945 – 0.997 0.0273 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.02 0.962 – 1.09 0.481 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.09 0.994 – 1.19 0.0676 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.932 0.841 – 1.03 0.179 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.01 0.926 – 1.11 0.778 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.07 0.984 – 1.17 0.113 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 0.98 0.935 – 1.03 0.395 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.915 0.786 – 1.07 0.256 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1 0.884 – 1.13 0.987 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.995 0.799 – 1.24 0.968 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.27 1.06 – 1.53 0.0109 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.13 0.932 – 1.37 0.214 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.808 0.618 – 1.06 0.119 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.979 0.744 – 1.29 0.879 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.01 0.884 – 1.15 0.876 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 0.994 0.92 – 1.07 0.886 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.924 0.799 – 1.07 0.291 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.07 0.837 – 1.38 0.572 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.04 0.849 – 1.27 0.72 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.973 0.8 – 1.18 0.785 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.961 0.769 – 1.2 0.726 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 0.997 0.961 – 1.03 0.887 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.01 0.972 – 1.05 0.646 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 1.01 0.972 – 1.05 0.646 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 1.02 0.994 – 1.05 0.119 5538 63928 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.04 0.993 – 1.1 0.0954 1663 19453 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.08 0.97 – 1.21 0.154 316 4512 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.03 0.941 – 1.12 0.542 514 6251 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.04 0.749 – 1.44 0.82 32 412 exclusion phecode
010 Tuberculosis Infectious Diseases 1.01 0.829 – 1.24 0.903 100 1154 exclusion phecode
038 Septicemia Infectious Diseases 1.04 0.991 – 1.08 0.116 2126 29197 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.04 0.947 – 1.15 0.385 415 5900 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.1 0.964 – 1.25 0.16 227 3457 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.04 1.02 – 1.07 0.000975 6955 85937 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.11 1.06 – 1.17 1.43e-05 1679 22196 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.04 0.98 – 1.11 0.18 976 11987 exclusion phecode
041.4 E. coli Infectious Diseases 1.06 1.01 – 1.11 0.0284 1520 19569 exclusion phecode
053 Herpes zoster Infectious Diseases 1.01 0.885 – 1.16 0.857 225 2821 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.705 0.525 – 0.946 0.0199 57 644 exclusion phecode
054 Herpes simplex Infectious Diseases 0.986 0.832 – 1.17 0.867 141 1606 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.04 0.935 – 1.17 0.44 323 4477 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.1 0.831 – 1.46 0.504 48 549 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 1.11 0.889 – 1.38 0.366 73 968 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.09 0.916 – 1.3 0.33 132 2012 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 0.895 0.75 – 1.07 0.217 140 2057 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.02 0.898 – 1.17 0.722 224 3107 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.06 0.853 – 1.33 0.581 73 1099 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.08 0.848 – 1.38 0.53 59 878 exclusion phecode
078 Viral warts & HPV Infectious Diseases 1.01 0.933 – 1.09 0.843 706 7578 exclusion phecode
079 Viral infection Infectious Diseases 0.988 0.942 – 1.04 0.605 1923 21181 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.921 0.685 – 1.24 0.586 46 518 exclusion phecode
080 Postoperative infection Infectious Diseases 1.03 0.994 – 1.07 0.1 2675 32311 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.06 1.01 – 1.12 0.0251 1363 17494 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.948 0.696 – 1.29 0.736 45 535 exclusion phecode
1000 Burns Injuries & Poisonings 0.97 0.874 – 1.08 0.567 381 4263 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 1.08 1.01 – 1.16 0.0341 822 8739 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.04 1 – 1.07 0.0306 3520 39155 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.03 0.888 – 1.19 0.729 191 2193 exclusion phecode
1005 Other symptoms Injuries & Poisonings 1.02 0.951 – 1.09 0.604 863 10313 exclusion phecode
1006 Crushing injury Injuries & Poisonings 0.934 0.799 – 1.09 0.393 176 1821 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 0.944 0.812 – 1.1 0.452 178 1913 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 0.955 0.884 – 1.03 0.237 707 7313 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 1.03 1.01 – 1.06 0.0114 5883 62296 exclusion phecode
1010 Other tests Injuries & Poisonings 0.987 0.955 – 1.02 0.44 3788 42750 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.01 0.985 – 1.04 0.369 5585 64404 exclusion phecode
1012 Late effect Injuries & Poisonings 1.09 0.868 – 1.38 0.446 76 764 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.06 0.924 – 1.22 0.39 199 2244 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.12 0.854 – 1.46 0.42 53 489 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 0.978 0.94 – 1.02 0.276 2671 31277 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.01 0.99 – 1.03 0.333 10738 116961 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.11 0.954 – 1.3 0.172 161 1992 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 1.13 0.968 – 1.33 0.121 157 1957 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.981 0.729 – 1.32 0.898 47 532 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.15 0.919 – 1.43 0.227 77 994 exclusion phecode
112 Candidiasis Infectious Diseases 1.05 0.991 – 1.11 0.0982 1280 15203 exclusion phecode
117 Mycoses Infectious Diseases 1.08 0.911 – 1.27 0.392 142 1917 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.05 0.85 – 1.31 0.631 85 1129 exclusion phecode
130 Spirochetal infection Infectious Diseases 1.02 0.78 – 1.34 0.88 54 603 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 1.06 0.785 – 1.42 0.721 44 522 exclusion phecode
134 Helminthiases Infectious Diseases 1.02 0.828 – 1.26 0.836 85 996 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 0.99 0.779 – 1.26 0.932 70 838 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.09 0.913 – 1.3 0.345 124 1464 exclusion phecode
145 Cancer of mouth Neoplasms 0.962 0.872 – 1.06 0.441 440 4516 exclusion phecode
145.2 Cancer of tongue Neoplasms 0.893 0.777 – 1.03 0.112 217 2145 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 1.1 0.868 – 1.4 0.422 68 791 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 0.984 0.7 – 1.38 0.926 37 369 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.92 0.83 – 1.02 0.114 392 4321 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 0.856 0.729 – 1.01 0.0582 170 1800 exclusion phecode
149.4 Cancer of larynx Neoplasms 0.959 0.812 – 1.13 0.621 140 1718 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.02 0.747 – 1.4 0.891 40 382 exclusion phecode
150 Cancer of esophagus Neoplasms 0.922 0.836 – 1.02 0.107 441 4965 exclusion phecode
151 Cancer of stomach Neoplasms 1.02 0.912 – 1.14 0.734 331 3675 exclusion phecode
153 Colorectal cancer Neoplasms 1.02 0.986 – 1.06 0.223 2982 31087 exclusion phecode
153.2 Colon cancer Neoplasms 1.05 1 – 1.09 0.0501 2015 20964 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.981 0.929 – 1.04 0.479 1419 14778 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.06 0.928 – 1.21 0.388 220 2702 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.06 0.843 – 1.34 0.609 69 1024 exclusion phecode
157 Pancreatic cancer Neoplasms 0.966 0.872 – 1.07 0.506 398 4402 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.01 0.933 – 1.09 0.821 686 7382 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1 0.97 – 1.04 0.85 3553 37731 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.1 0.928 – 1.31 0.27 130 1326 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.941 0.788 – 1.12 0.505 131 1394 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.987 0.825 – 1.18 0.887 122 1346 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 1.19 0.876 – 1.62 0.264 41 409 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.01 0.956 – 1.06 0.835 1593 18688 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.06 1 – 1.12 0.0461 1233 14797 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 1.09 0.972 – 1.23 0.137 295 3027 exclusion phecode
170.1 Bone cancer Neoplasms 1.3 1.05 – 1.61 0.0166 84 899 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1.03 0.896 – 1.18 0.689 225 2294 exclusion phecode
172 Skin cancer Neoplasms 0.991 0.97 – 1.01 0.408 9327 92779 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.961 0.916 – 1.01 0.0964 1928 19087 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.964 0.92 – 1.01 0.131 1951 19315 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.992 0.969 – 1.02 0.493 7542 74823 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 1.15 1.04 – 1.27 0.00613 406 4415 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.976 0.816 – 1.17 0.793 128 1321 exclusion phecode
174 Breast cancer Neoplasms 1.01 0.988 – 1.03 0.395 9487 97258 exclusion phecode
174.1 Breast cancer [female] Neoplasms 1.01 0.987 – 1.03 0.458 9353 95789 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.01 0.984 – 1.03 0.592 8789 90219 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.02 0.826 – 1.26 0.865 93 905 exclusion phecode
175 Acquired absence of breast Neoplasms 0.996 0.948 – 1.05 0.881 1768 18613 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 0.999 0.951 – 1.05 0.974 1779 18031 exclusion phecode
180.1 Cervical cancer Neoplasms 1.03 0.895 – 1.18 0.686 214 2176 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.983 0.935 – 1.03 0.507 1703 17213 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.984 0.917 – 1.06 0.655 847 9520 exclusion phecode
184 Cancer of other female genital organs Neoplasms 0.986 0.924 – 1.05 0.669 1010 10505 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.971 0.898 – 1.05 0.459 715 7284 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.964 0.89 – 1.04 0.359 693 7046 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.961 0.836 – 1.1 0.574 219 2371 exclusion phecode
185 Cancer of prostate Neoplasms 1.02 0.99 – 1.06 0.164 3690 35865 exclusion phecode
187 Cancer of other male genital organs Neoplasms 1.06 0.945 – 1.18 0.331 304 3153 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.36 1 – 1.83 0.0466 40 438 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 1.03 0.898 – 1.19 0.65 199 2112 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.908 0.721 – 1.15 0.417 75 735 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.04 0.996 – 1.09 0.0789 2136 27012 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.09 0.995 – 1.21 0.0644 403 7221 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.1 0.994 – 1.21 0.0643 383 6951 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.08 0.76 – 1.53 0.677 31 434 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.01 0.958 – 1.07 0.676 1356 15398 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1 0.946 – 1.06 0.924 1195 13676 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.06 0.821 – 1.36 0.662 58 938 exclusion phecode
190 Cancer of eye Neoplasms 0.91 0.753 – 1.1 0.33 122 1233 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.929 0.843 – 1.02 0.133 471 4848 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.947 0.852 – 1.05 0.317 389 3944 exclusion phecode
191.11 Cancer of brain Neoplasms 0.955 0.856 – 1.07 0.407 362 3669 exclusion phecode
193 Thyroid cancer Neoplasms 1.17 1.03 – 1.33 0.013 234 2652 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 0.943 0.719 – 1.24 0.67 58 701 exclusion phecode
195 Cancer, suspected or other Neoplasms 0.999 0.98 – 1.02 0.939 11114 116438 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 0.997 0.978 – 1.02 0.78 10621 111911 exclusion phecode
197 Chemotherapy Neoplasms 1.01 0.995 – 1.03 0.148 14014 156042 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.02 0.998 – 1.05 0.0661 6170 67750 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.03 0.998 – 1.07 0.0642 3642 38998 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.993 0.94 – 1.05 0.792 1380 15988 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.01 0.951 – 1.08 0.67 1009 11039 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.03 0.981 – 1.08 0.236 1657 18449 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.988 0.904 – 1.08 0.796 527 6027 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.05 0.992 – 1.11 0.0953 1291 14889 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.827 0.68 – 1 0.0552 119 1353 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.05 0.976 – 1.12 0.205 841 10306 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.14 0.845 – 1.54 0.389 39 706 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.09 1 – 1.2 0.0512 480 6747 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.17 1.01 – 1.36 0.0405 162 2584 exclusion phecode
201 Hodgkin's disease Neoplasms 0.948 0.806 – 1.12 0.522 160 1976 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.05 0.989 – 1.1 0.115 1288 15846 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.05 0.987 – 1.12 0.125 1012 12512 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.17 1.02 – 1.33 0.0205 220 2507 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.1 0.992 – 1.23 0.0693 328 4022 exclusion phecode
204 Leukemia Neoplasms 1.05 0.98 – 1.12 0.173 926 11320 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1.09 0.973 – 1.21 0.138 317 3872 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.05 0.735 – 1.5 0.79 34 413 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.1 0.974 – 1.24 0.126 270 3393 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.08 0.954 – 1.21 0.235 271 3228 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 1.1 0.95 – 1.27 0.206 182 2296 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.14 0.935 – 1.38 0.198 103 1010 exclusion phecode
204.4 Multiple myeloma Neoplasms 0.953 0.844 – 1.08 0.437 287 3744 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1.01 0.988 – 1.02 0.55 12795 134394 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.979 0.906 – 1.06 0.594 681 7213 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.05 1.02 – 1.09 0.00374 3571 37441 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.01 0.883 – 1.15 0.9 234 2505 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.992 0.868 – 1.13 0.9 244 2393 exclusion phecode
214 Lipoma Neoplasms 1.01 0.98 – 1.04 0.497 4392 45251 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.02 0.981 – 1.05 0.363 3277 33835 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.11 1.03 – 1.19 0.00389 820 8233 exclusion phecode
216 Benign neoplasm of skin Neoplasms 1 0.975 – 1.03 0.906 5724 57581 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.02 0.922 – 1.12 0.749 435 4529 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 1.01 0.917 – 1.12 0.802 409 4246 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.991 0.968 – 1.01 0.441 8074 81251 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 0.991 0.968 – 1.01 0.415 8240 82633 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.907 0.799 – 1.03 0.132 269 2832 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.988 0.928 – 1.05 0.71 1120 11458 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.884 0.754 – 1.04 0.128 173 1750 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 1.35 1.1 – 1.64 0.00345 94 1038 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.22 1.01 – 1.47 0.0383 100 1152 exclusion phecode
224 Benign neoplasm of eye Neoplasms 1.27 1.02 – 1.57 0.0317 78 954 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.44 1.05 – 1.97 0.0219 37 458 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.942 0.863 – 1.03 0.183 563 5999 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.955 0.873 – 1.04 0.314 528 5694 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.932 0.675 – 1.29 0.671 43 455 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.87 0.747 – 1.01 0.0744 196 2039 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.04 0.954 – 1.13 0.374 548 6287 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.11 0.922 – 1.34 0.264 106 1354 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.05 0.928 – 1.2 0.414 237 2662 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.02 0.878 – 1.17 0.838 204 2262 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.938 0.882 – 0.997 0.0413 1141 11659 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.02 0.973 – 1.07 0.399 1842 18187 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.1 0.996 – 1.21 0.0611 414 4535 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.982 0.912 – 1.06 0.623 779 8411 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.1 0.987 – 1.23 0.0856 357 3598 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.905 0.821 – 0.998 0.0464 451 5090 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.04 0.977 – 1.1 0.231 1162 13999 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 1 0.895 – 1.12 0.963 327 3632 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.13 0.879 – 1.44 0.35 57 715 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.992 0.803 – 1.23 0.944 95 1059 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.03 1 – 1.05 0.0213 9219 108660 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.07 0.991 – 1.15 0.083 700 8273 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.936 0.715 – 1.22 0.628 60 769 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.02 1 – 1.05 0.04 8765 103937 exclusion phecode
245 Thyroiditis Endocrine/metabolic 0.889 0.768 – 1.03 0.114 201 2279 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.896 0.759 – 1.06 0.197 153 1716 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.897 0.756 – 1.06 0.209 145 1639 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.02 0.896 – 1.15 0.802 260 3014 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.02 0.998 – 1.04 0.0758 10925 131077 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.964 0.915 – 1.02 0.175 1489 19737 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.841 0.702 – 1.01 0.0599 140 1800 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.97 0.552 – 1.7 0.916 8 556 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.936 0.818 – 1.07 0.342 222 3357 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 0.859 0.649 – 1.14 0.286 51 1141 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.02 0.998 – 1.04 0.0836 9579 118577 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.959 0.74 – 1.24 0.749 61 768 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.21 0.846 – 1.72 0.301 25 1338 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.01 0.917 – 1.12 0.789 397 6711 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.01 0.866 – 1.18 0.899 164 3447 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 0.978 0.882 – 1.08 0.666 400 4888 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.996 0.852 – 1.16 0.955 172 1858 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.978 0.853 – 1.12 0.743 228 3014 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.935 0.756 – 1.16 0.532 104 1107 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.911 0.76 – 1.09 0.311 124 2404 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.982 0.904 – 1.07 0.659 596 9087 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 0.897 0.814 – 0.988 0.0272 451 6676 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.09 0.994 – 1.2 0.0659 461 6281 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.06 0.961 – 1.17 0.246 417 5639 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.26 0.985 – 1.6 0.0656 59 1003 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.02 0.921 – 1.12 0.742 413 4880 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.04 0.871 – 1.25 0.64 122 1392 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.3 1.02 – 1.66 0.0333 61 699 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.987 0.836 – 1.17 0.88 143 1869 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.633 0.454 – 0.884 0.00724 47 715 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.1 0.914 – 1.33 0.31 107 1033 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.961 0.858 – 1.08 0.486 337 4714 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.12 0.911 – 1.39 0.275 90 1352 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.08 0.824 – 1.42 0.57 52 805 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.18 0.85 – 1.63 0.326 38 549 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.94 0.807 – 1.1 0.433 185 2651 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.942 0.808 – 1.1 0.443 185 2645 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 1.03 0.887 – 1.19 0.718 204 2141 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.996 0.85 – 1.17 0.962 174 1876 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1.01 0.814 – 1.24 0.958 87 1131 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.01 0.809 – 1.26 0.926 80 1064 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.944 0.726 – 1.23 0.67 55 752 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 0.906 0.735 – 1.12 0.355 102 1134 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.872 0.723 – 1.05 0.153 117 1414 exclusion phecode
260.1 Cachexia Endocrine/metabolic 0.985 0.676 – 1.44 0.936 27 340 exclusion phecode
260.6 Anorexia Endocrine/metabolic 0.958 0.875 – 1.05 0.355 494 5856 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.01 0.936 – 1.09 0.778 692 8706 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.02 0.925 – 1.12 0.709 440 5454 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.03 0.91 – 1.17 0.632 258 3312 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1 0.728 – 1.38 0.982 36 575 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.893 0.753 – 1.06 0.19 152 1775 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.05 0.897 – 1.24 0.52 158 2372 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.09 0.939 – 1.27 0.255 160 2051 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.12 0.95 – 1.32 0.18 134 1749 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.15 0.949 – 1.38 0.156 94 1263 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1 0.772 – 1.3 0.978 55 764 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 0.987 0.711 – 1.37 0.938 36 475 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.11 0.917 – 1.35 0.281 109 1184 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.08 0.88 – 1.33 0.459 99 1039 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.01 0.994 – 1.02 0.242 20417 170572 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.01 0.994 – 1.02 0.256 20374 170389 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.01 0.996 – 1.03 0.151 18889 164486 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.971 0.702 – 1.34 0.859 38 411 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.05 0.848 – 1.3 0.647 84 1154 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.18 0.99 – 1.41 0.064 118 1442 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.06 1.01 – 1.11 0.023 1596 24798 exclusion phecode
274.1 Gout Endocrine/metabolic 1.05 0.992 – 1.11 0.0914 1237 20817 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.07 0.818 – 1.41 0.609 51 735 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.11 1 – 1.23 0.0414 384 4360 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.12 1.01 – 1.25 0.0344 356 3988 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.09 1.03 – 1.16 0.00241 1172 14742 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 1.07 0.975 – 1.18 0.146 423 4588 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.16 1.01 – 1.33 0.0359 200 2573 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.1 1.02 – 1.2 0.0149 610 8470 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.05 0.855 – 1.28 0.656 100 1209 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.03 0.998 – 1.07 0.0646 3665 50343 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.06 1.01 – 1.1 0.0151 2110 28095 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.15 0.97 – 1.37 0.106 121 1585 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.02 0.963 – 1.09 0.44 1071 12445 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.11 0.996 – 1.24 0.0583 311 6533 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.08 1 – 1.16 0.0415 773 10104 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 0.98 0.894 – 1.08 0.674 470 7952 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.02 0.927 – 1.12 0.675 420 7243 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 0.729 0.539 – 0.986 0.0404 52 746 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.01 0.956 – 1.06 0.754 1409 19646 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.24 1.06 – 1.44 0.00572 151 3022 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 0.916 0.736 – 1.14 0.43 88 971 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.05 0.966 – 1.15 0.235 517 6497 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.969 0.851 – 1.1 0.634 238 2573 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.01 0.845 – 1.2 0.922 132 1611 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.16 0.792 – 1.7 0.444 26 367 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.09 1.06 – 1.12 1.2e-10 5600 79880 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.09 1.06 – 1.12 7.92e-11 5501 78655 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 0.995 0.776 – 1.28 0.969 61 686 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.17 0.846 – 1.62 0.34 32 510 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.07 0.903 – 1.26 0.453 144 1853 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.04 0.873 – 1.25 0.64 121 1545 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.06 0.847 – 1.34 0.594 77 1012 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.02 0.872 – 1.2 0.787 164 1594 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.02 0.991 – 1.05 0.183 4717 56023 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.02 0.988 – 1.05 0.239 4497 53665 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.99 0.883 – 1.11 0.864 322 3555 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.06 0.975 – 1.15 0.18 613 8034 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.06 0.971 – 1.15 0.203 593 7703 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.04 0.947 – 1.15 0.395 430 5434 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.17 0.966 – 1.43 0.107 103 1327 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 1.03 0.824 – 1.28 0.815 80 1277 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.26 0.845 – 1.88 0.258 23 369 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 0.963 0.77 – 1.2 0.741 77 1087 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 0.905 0.645 – 1.27 0.563 33 406 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.02 0.749 – 1.39 0.903 42 618 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.02 0.793 – 1.32 0.87 59 972 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.928 0.689 – 1.25 0.624 45 730 exclusion phecode
284 Aplastic anemia Hematopoietic 1.17 1.03 – 1.34 0.0197 200 3051 exclusion phecode
285 Other anemias Hematopoietic 1.02 0.999 – 1.05 0.0551 7059 87513 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.96 0.828 – 1.11 0.595 185 2064 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.14 1.01 – 1.28 0.0317 268 4887 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.14 1.01 – 1.3 0.0357 235 2923 exclusion phecode
286 Coagulation defects Hematopoietic 0.962 0.881 – 1.05 0.39 557 6766 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.91 0.808 – 1.03 0.124 317 3459 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.839 0.646 – 1.09 0.188 74 734 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.917 0.791 – 1.06 0.249 201 2233 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 0.971 0.705 – 1.34 0.856 38 460 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.4 0.994 – 1.97 0.0545 29 569 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.975 0.849 – 1.12 0.719 218 2823 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.08 1.01 – 1.15 0.0351 868 11543 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.03 0.823 – 1.29 0.804 80 916 exclusion phecode
287.2 Allergic purpura Hematopoietic 1.06 0.765 – 1.46 0.732 30 395 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.06 0.983 – 1.13 0.135 812 10830 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 0.946 0.822 – 1.09 0.44 214 2939 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.969 0.683 – 1.37 0.858 32 507 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.05 1.01 – 1.09 0.0278 2279 27246 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.04 0.997 – 1.09 0.0654 1930 22983 exclusion phecode
288.11 Neutropenia Hematopoietic 1.04 0.996 – 1.09 0.0753 1937 23042 exclusion phecode
288.3 Eosinophilia Hematopoietic 1.29 0.959 – 1.75 0.0917 40 499 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.07 0.979 – 1.18 0.13 474 6221 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.989 0.845 – 1.16 0.893 164 2167 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.03 0.983 – 1.09 0.188 1575 18736 exclusion phecode
289.5 Diseases of spleen Hematopoietic 0.963 0.855 – 1.08 0.532 291 3627 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.06 0.902 – 1.26 0.464 133 2006 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.29 0.947 – 1.76 0.106 38 649 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.972 0.911 – 1.04 0.379 1010 12458 exclusion phecode
290.1 Dementias Mental Disorders 0.981 0.899 – 1.07 0.669 540 6269 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 1 0.88 – 1.14 0.985 252 2750 exclusion phecode
290.16 Vascular dementia Mental Disorders 0.951 0.78 – 1.16 0.617 99 1219 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.906 0.807 – 1.02 0.0924 328 4252 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.05 0.785 – 1.41 0.736 42 558 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.96 0.875 – 1.05 0.389 499 6087 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.04 0.845 – 1.29 0.691 95 1045 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.887 0.753 – 1.05 0.152 163 1978 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.01 0.889 – 1.15 0.874 255 3192 exclusion phecode
292 Neurological disorders Mental Disorders 1.04 1 – 1.08 0.0523 2712 31905 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.02 0.958 – 1.09 0.491 906 10596 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.926 0.755 – 1.14 0.462 99 1299 exclusion phecode
292.3 Memory loss Mental Disorders 1.01 0.925 – 1.11 0.756 469 4916 exclusion phecode
292.4 Altered mental status Mental Disorders 1.04 0.981 – 1.1 0.191 1211 14671 exclusion phecode
292.6 Hallucinations Mental Disorders 1.13 0.977 – 1.32 0.0984 171 2166 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.03 0.973 – 1.08 0.339 1419 15198 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.994 0.914 – 1.08 0.881 605 6623 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.971 0.885 – 1.07 0.539 493 6382 exclusion phecode
295.1 Schizophrenia Mental Disorders 1 0.896 – 1.12 0.96 326 4364 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.01 0.836 – 1.23 0.901 111 1363 exclusion phecode
295.3 Psychosis Mental Disorders 0.866 0.702 – 1.07 0.179 101 1317 exclusion phecode
296 Mood disorders Mental Disorders 1.04 1.02 – 1.07 0.000358 8082 94942 exclusion phecode
296.1 Bipolar Mental Disorders 1.04 0.964 – 1.13 0.287 632 8089 exclusion phecode
296.2 Depression Mental Disorders 1.04 1.02 – 1.07 0.000457 7697 90087 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.01 0.881 – 1.15 0.904 228 2742 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.914 0.792 – 1.06 0.22 208 2413 exclusion phecode
300 Anxiety disorders Mental Disorders 1.01 0.979 – 1.04 0.563 4624 51851 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.01 0.978 – 1.04 0.556 4282 47836 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 0.937 0.77 – 1.14 0.513 109 1153 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.04 0.951 – 1.15 0.361 474 5403 exclusion phecode
300.13 Phobia Mental Disorders 1.03 0.923 – 1.16 0.566 326 3766 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.821 0.658 – 1.02 0.0797 97 1080 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.26 0.926 – 1.72 0.14 37 419 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.05 0.847 – 1.3 0.66 86 965 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.13 0.903 – 1.42 0.28 80 891 exclusion phecode
301 Personality disorders Mental Disorders 1.14 0.992 – 1.31 0.0639 203 2700 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.23 0.982 – 1.54 0.0721 74 1010 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 1.04 0.892 – 1.22 0.59 162 1890 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.08 0.965 – 1.21 0.183 327 3543 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 1.05 0.923 – 1.19 0.456 252 2625 exclusion phecode
303.4 Somatoform disorder Mental Disorders 1.07 0.857 – 1.32 0.567 82 960 exclusion phecode
304 Adjustment reaction Mental Disorders 0.942 0.812 – 1.09 0.437 202 2288 exclusion phecode
305.2 Eating disorder Mental Disorders 0.997 0.782 – 1.27 0.984 73 763 exclusion phecode
306 Other mental disorder Mental Disorders 1.02 1 – 1.04 0.01 17030 167354 exclusion phecode
306.9 Tension headache Mental Disorders 1.02 0.887 – 1.17 0.774 218 2489 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 1.02 0.78 – 1.33 0.897 54 593 exclusion phecode
313.3 Autism Mental Disorders 1.2 0.891 – 1.62 0.229 39 409 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.03 0.89 – 1.18 0.722 200 2513 exclusion phecode
315.1 Learning disorder Mental Disorders 0.983 0.788 – 1.23 0.877 83 1248 exclusion phecode
315.2 Speech and language disorder Mental Disorders 0.972 0.726 – 1.3 0.846 50 615 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.01 0.977 – 1.05 0.502 3375 39026 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.01 0.715 – 1.43 0.949 31 449 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.01 0.984 – 1.03 0.591 8591 92459 exclusion phecode
317.1 Alcoholism Mental Disorders 1 0.975 – 1.03 0.955 6050 64215 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1 0.912 – 1.1 0.965 450 6050 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.04 1.02 – 1.06 3.24e-05 11090 136722 exclusion phecode
320 Meningitis Neurological 1.01 0.9 – 1.13 0.87 314 3432 exclusion phecode
323 Encephalitis Neurological 1.08 0.952 – 1.23 0.224 242 2561 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 1.18 0.923 – 1.5 0.191 62 590 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1.18 1.02 – 1.36 0.03 186 2017 exclusion phecode
327 Sleep disorders Neurological 1.1 1.02 – 1.18 0.0107 753 8299 exclusion phecode
327.3 Sleep apnea Neurological 1.03 0.993 – 1.08 0.105 2509 31613 exclusion phecode
327.4 Insomnia Neurological 1.08 0.896 – 1.31 0.405 106 1206 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1.17 0.956 – 1.44 0.125 89 1012 exclusion phecode
331 Other cerebral degenerations Neurological 1.02 0.94 – 1.1 0.684 688 7941 exclusion phecode
331.1 Hydrocephalus Neurological 0.937 0.833 – 1.05 0.276 320 3620 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 1.12 0.984 – 1.27 0.0869 245 2859 exclusion phecode
332 Parkinson's disease Neurological 1.04 0.965 – 1.12 0.3 696 7283 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.07 0.98 – 1.16 0.137 563 6369 exclusion phecode
333.1 Essential tremor Neurological 1.17 0.979 – 1.4 0.0845 119 1443 exclusion phecode
333.2 Myoclonus Neurological 1.09 0.847 – 1.4 0.506 65 700 exclusion phecode
333.4 Torsion dystonia Neurological 0.914 0.777 – 1.07 0.274 169 1872 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.01 0.948 – 1.07 0.795 1142 12828 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.15 0.9 – 1.47 0.264 65 836 exclusion phecode
334.2 Anterior horn cell disease Neurological 1.14 0.974 – 1.34 0.102 159 1626 exclusion phecode
335 Multiple sclerosis Neurological 0.995 0.931 – 1.06 0.87 1001 10396 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.06 0.903 – 1.24 0.483 157 1874 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 0.921 0.66 – 1.28 0.626 36 467 exclusion phecode
338 Pain Neurological 1.1 1 – 1.21 0.0394 465 5734 exclusion phecode
338.1 Acute pain Neurological 1.12 0.982 – 1.28 0.0925 226 2898 exclusion phecode
338.2 Chronic pain Neurological 1.07 0.939 – 1.21 0.317 242 2934 exclusion phecode
339 Other headache syndromes Neurological 1.02 0.991 – 1.05 0.185 5457 59083 exclusion phecode
340 Migraine Neurological 0.982 0.939 – 1.03 0.443 2104 22427 exclusion phecode
340.1 Migrain with aura Neurological 0.922 0.779 – 1.09 0.344 154 1692 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.979 0.843 – 1.14 0.781 196 1993 exclusion phecode
342 Hemiplegia Neurological 1.05 0.983 – 1.13 0.136 811 10529 exclusion phecode
343 Infantile cerebral palsy Neurological 0.828 0.671 – 1.02 0.0782 101 1092 exclusion phecode
344 Other paralytic syndromes Neurological 1.07 0.967 – 1.18 0.194 415 4841 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1 0.967 – 1.04 0.963 3449 36984 exclusion phecode
345.1 Epilepsy Neurological 0.983 0.903 – 1.07 0.696 600 6422 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.04 0.93 – 1.17 0.479 313 3237 exclusion phecode
345.12 Partial epilepsy Neurological 0.988 0.854 – 1.14 0.869 200 2113 exclusion phecode
345.3 Convulsions Neurological 0.987 0.936 – 1.04 0.612 1513 16471 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.05 0.856 – 1.29 0.633 91 1064 exclusion phecode
348 Other conditions of brain Neurological 1.04 0.951 – 1.15 0.371 469 5731 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.06 0.904 – 1.24 0.479 159 2021 exclusion phecode
348.4 Cerebral cysts Neurological 1.12 0.916 – 1.38 0.262 97 1023 exclusion phecode
348.7 Coma Neurological 1.05 0.924 – 1.19 0.463 244 2540 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.02 0.866 – 1.21 0.782 147 1803 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 0.933 0.823 – 1.06 0.284 266 2780 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.05 0.922 – 1.2 0.447 221 2482 exclusion phecode
350 Abnormal movement Neurological 1.06 1.01 – 1.12 0.0227 1558 18808 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.05 0.963 – 1.14 0.271 540 6480 exclusion phecode
350.2 Abnormality of gait Neurological 1.05 0.983 – 1.12 0.145 884 10945 exclusion phecode
350.3 Lack of coordination Neurological 1.1 0.961 – 1.25 0.17 223 2634 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.973 0.707 – 1.34 0.868 39 397 exclusion phecode
351 Other peripheral nerve disorders Neurological 1 0.98 – 1.02 0.835 8509 92624 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.05 0.977 – 1.12 0.2 903 9985 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1 0.892 – 1.12 0.998 319 3438 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.02 0.94 – 1.12 0.58 565 6376 exclusion phecode
353 Nerve root and plexus disorders Neurological 1.04 0.961 – 1.12 0.344 692 8200 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.924 0.732 – 1.17 0.505 79 883 exclusion phecode
353.2 Nerve root lesions Neurological 1.14 0.834 – 1.57 0.405 36 413 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.21 0.997 – 1.47 0.0539 93 1075 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.17 1.09 – 1.26 1.19e-05 759 9463 exclusion phecode
358 Myoneural disorders Neurological 1.03 0.854 – 1.24 0.765 113 1447 exclusion phecode
358.1 Myasthenia gravis Neurological 1.06 0.87 – 1.28 0.585 105 1336 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 1.13 0.999 – 1.28 0.0516 245 3358 exclusion phecode
359.1 Muscular dystrophies Neurological 1.01 0.785 – 1.29 0.948 61 888 exclusion phecode
359.2 Myopathy Neurological 1.18 1.03 – 1.36 0.0209 190 2586 exclusion phecode
360 Disorders of the globe Sense Organs 0.941 0.819 – 1.08 0.391 226 2287 exclusion phecode
360.2 Progressive myopia Sense Organs 0.992 0.846 – 1.16 0.919 167 1721 exclusion phecode
361 Retinal detachments and defects Sense Organs 1.02 0.98 – 1.07 0.303 2307 22703 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.02 0.953 – 1.09 0.604 980 9779 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.878 0.634 – 1.22 0.436 40 490 exclusion phecode
362 Other retinal disorders Sense Organs 1.04 0.999 – 1.08 0.0545 2379 25973 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.05 0.999 – 1.11 0.0552 1374 14566 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.05 0.998 – 1.11 0.0582 1372 14540 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.12 0.925 – 1.36 0.245 106 1132 exclusion phecode
362.31 Separation of retinal layers Sense Organs 1.09 0.864 – 1.37 0.47 76 683 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.1 1.01 – 1.21 0.0373 475 5694 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.936 0.78 – 1.12 0.476 126 1302 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.743 0.559 – 0.987 0.0406 61 584 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.939 0.75 – 1.18 0.582 79 801 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.01 0.827 – 1.23 0.923 104 1221 exclusion phecode
363.3 Chorioretinal scars Sense Organs 1.15 0.83 – 1.58 0.406 34 506 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.991 0.898 – 1.09 0.852 440 4556 exclusion phecode
364.1 Corneal opacity Sense Organs 1.07 0.821 – 1.38 0.633 58 650 exclusion phecode
364.2 Corneal edema Sense Organs 1.04 0.759 – 1.41 0.824 43 547 exclusion phecode
364.4 Corneal degenerations Sense Organs 1.14 0.963 – 1.34 0.13 149 1459 exclusion phecode
364.41 Keratoconus Sense Organs 1.06 0.835 – 1.35 0.62 66 667 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.906 0.756 – 1.09 0.287 136 1407 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.954 0.742 – 1.23 0.71 69 706 exclusion phecode
365 Glaucoma Sense Organs 1.01 0.975 – 1.05 0.506 2838 29671 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 1.01 0.93 – 1.09 0.898 674 6777 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 1.01 0.934 – 1.09 0.804 670 6746 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.985 0.897 – 1.08 0.752 477 4805 exclusion phecode
366 Cataract Sense Organs 1.01 0.992 – 1.03 0.289 12277 115766 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 0.905 0.665 – 1.23 0.528 42 517 exclusion phecode
366.2 Senile cataract Sense Organs 1.01 0.986 – 1.04 0.318 5021 54573 exclusion phecode
366.3 Traumatic cataract Sense Organs 1.19 0.949 – 1.49 0.132 69 681 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.999 0.95 – 1.05 0.983 1610 16847 exclusion phecode
367.1 Myopia Sense Organs 1.01 0.946 – 1.09 0.714 880 8778 exclusion phecode
367.2 Astigmatism Sense Organs 0.961 0.8 – 1.16 0.675 124 1340 exclusion phecode
367.8 Hypermetropia Sense Organs 1.01 0.86 – 1.18 0.911 162 1737 exclusion phecode
367.9 Blindness and low vision Sense Organs 0.994 0.901 – 1.1 0.908 439 4993 exclusion phecode
368 Visual disturbances Sense Organs 1.05 1 – 1.1 0.0362 1896 21389 exclusion phecode
368.1 Amblyopia Sense Organs 1 0.896 – 1.13 0.936 320 3683 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.995 0.904 – 1.09 0.916 454 5275 exclusion phecode
368.3 Anisometropia Sense Organs 1.1 0.906 – 1.33 0.342 103 1123 exclusion phecode
368.4 Visual field defects Sense Organs 1.1 0.957 – 1.26 0.183 209 2315 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 1.15 1.04 – 1.27 0.00627 395 4538 exclusion phecode
369 Infection of the eye Sense Organs 1.07 0.964 – 1.2 0.196 353 4013 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.967 0.762 – 1.23 0.785 72 887 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 1.04 0.868 – 1.23 0.701 131 1554 exclusion phecode
370 Keratitis Sense Organs 1.02 0.883 – 1.18 0.768 190 2088 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.925 0.751 – 1.14 0.464 97 1021 exclusion phecode
371 Inflammation of the eye Sense Organs 1.03 0.988 – 1.08 0.159 2192 22200 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.1 0.989 – 1.23 0.0789 307 3471 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 1.01 0.961 – 1.06 0.708 1752 17237 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.05 0.961 – 1.14 0.29 529 5408 exclusion phecode
374 Other disorders of eyelids Sense Organs 1.01 0.977 – 1.04 0.572 3803 40161 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.987 0.911 – 1.07 0.74 641 6965 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.984 0.928 – 1.04 0.592 1222 12800 exclusion phecode
375 Disorders of lacrimal system Sense Organs 1.01 0.962 – 1.07 0.601 1523 15626 exclusion phecode
375.2 Epiphora Sense Organs 1.03 0.953 – 1.12 0.435 636 6274 exclusion phecode
376 Disorders of the orbit Sense Organs 0.898 0.677 – 1.19 0.452 52 610 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.931 0.81 – 1.07 0.309 228 2651 exclusion phecode
377.1 Optic atrophy Sense Organs 0.982 0.708 – 1.36 0.914 34 417 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.04 0.833 – 1.29 0.754 87 959 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.959 0.896 – 1.03 0.218 958 10370 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.936 0.863 – 1.02 0.115 651 6823 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.02 0.853 – 1.22 0.823 125 1501 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.05 0.894 – 1.23 0.572 171 1962 exclusion phecode
379 Other disorders of eye Sense Organs 0.997 0.956 – 1.04 0.872 2311 25287 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 1.01 0.944 – 1.08 0.754 875 9435 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.989 0.93 – 1.05 0.727 1086 12029 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1 0.755 – 1.33 0.979 49 522 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.07 0.945 – 1.2 0.299 262 2833 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.982 0.805 – 1.2 0.857 102 1236 exclusion phecode
380 Disorders of external ear Sense Organs 1.01 0.917 – 1.11 0.852 448 4445 exclusion phecode
380.1 Otitis externa Sense Organs 1.05 0.94 – 1.18 0.377 342 3761 exclusion phecode
380.4 Impacted cerumen Sense Organs 1.02 0.899 – 1.16 0.756 250 2575 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.972 0.92 – 1.03 0.312 1414 15684 exclusion phecode
381.1 Otitis media Sense Organs 0.968 0.911 – 1.03 0.3 1156 12856 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.991 0.909 – 1.08 0.844 553 6278 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.929 0.778 – 1.11 0.417 135 1457 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 1.14 0.945 – 1.38 0.17 113 1243 exclusion phecode
381.9 Otorrhea Sense Organs 0.893 0.764 – 1.04 0.151 185 2030 exclusion phecode
382 Otalgia Sense Organs 1.05 0.911 – 1.2 0.527 219 2306 exclusion phecode
383 Otosclerosis Sense Organs 1.01 0.88 – 1.15 0.936 232 2353 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 0.982 0.918 – 1.05 0.605 919 9595 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 0.984 0.912 – 1.06 0.685 732 7653 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.03 0.941 – 1.12 0.543 527 5736 exclusion phecode
385.3 Cholesteatoma Sense Organs 1.01 0.911 – 1.12 0.867 400 4423 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.04 0.892 – 1.21 0.622 170 1806 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.07 1.01 – 1.14 0.0214 1156 12518 exclusion phecode
386.1 Meniere's disease Sense Organs 1.16 1.05 – 1.28 0.00458 369 4126 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 1.04 0.918 – 1.19 0.516 250 2655 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.05 0.958 – 1.14 0.321 515 5560 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.03 0.992 – 1.07 0.122 2850 32587 exclusion phecode
388 Other disorders of ear Sense Organs 1.13 0.958 – 1.34 0.145 141 1463 exclusion phecode
389 Hearing loss Sense Organs 1.01 0.972 – 1.05 0.58 2628 29264 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.986 0.875 – 1.11 0.824 296 3179 exclusion phecode
389.2 Conductive hearing loss Sense Organs 0.957 0.849 – 1.08 0.475 296 3354 exclusion phecode
389.4 Tinnitus Sense Organs 0.959 0.857 – 1.07 0.471 336 3644 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.05 1.01 – 1.1 0.00789 2638 32790 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.09 1.03 – 1.14 0.000995 1639 20116 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.03 0.951 – 1.11 0.479 661 8535 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.07 0.981 – 1.16 0.128 555 7030 exclusion phecode
395 Heart valve disorders Circulatory System 1.07 1.03 – 1.12 0.00128 2254 28234 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.09 1.04 – 1.14 0.00076 1586 19409 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.1 0.916 – 1.31 0.317 132 1822 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 0.986 0.757 – 1.28 0.919 57 709 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.989 0.758 – 1.29 0.936 51 657 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.05 0.972 – 1.13 0.225 743 9813 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.05 0.968 – 1.13 0.25 700 7655 exclusion phecode
401 Hypertension Circulatory System 1.02 1.01 – 1.03 0.000367 43185 207901 exclusion phecode
401.1 Essential hypertension Circulatory System 1.02 1.01 – 1.03 0.00034 43131 207712 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.08 0.973 – 1.19 0.153 349 13252 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.1 0.945 – 1.28 0.219 157 2564 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.09 0.951 – 1.25 0.216 192 10832 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.16 0.816 – 1.64 0.415 29 1048 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.03 0.96 – 1.1 0.428 908 10889 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.01 0.997 – 1.03 0.108 17437 150784 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.03 0.989 – 1.07 0.166 2818 35061 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.02 0.99 – 1.04 0.242 6320 76419 exclusion phecode
411.3 Angina pectoris Circulatory System 0.999 0.977 – 1.02 0.91 8723 98965 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.01 0.991 – 1.03 0.305 11218 107549 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1 0.909 – 1.11 0.964 424 4851 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.01 0.99 – 1.04 0.275 7773 89870 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.996 0.923 – 1.07 0.908 695 8291 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 0.995 0.93 – 1.07 0.895 879 12319 exclusion phecode
414.2 ASCVD Circulatory System 1.05 0.766 – 1.44 0.767 38 477 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.04 0.999 – 1.08 0.0578 2401 31183 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.956 0.712 – 1.29 0.767 44 513 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.1 0.97 – 1.24 0.139 266 4029 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.05 0.91 – 1.21 0.502 197 3027 exclusion phecode
416 Cardiomegaly Circulatory System 1.03 0.975 – 1.09 0.288 1300 17990 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.03 1.01 – 1.04 0.000652 18523 198416 exclusion phecode
418.1 Precordial pain Circulatory System 1.05 1 – 1.09 0.0391 2284 25880 exclusion phecode
420 Carditis Circulatory System 1.07 1.01 – 1.13 0.0235 1212 14499 exclusion phecode
420.1 Myocarditis Circulatory System 1.04 0.822 – 1.32 0.727 74 906 exclusion phecode
420.2 Pericarditis Circulatory System 1.11 1.04 – 1.19 0.00288 783 9266 exclusion phecode
420.21 Acute pericarditis Circulatory System 0.989 0.841 – 1.16 0.894 152 1553 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.1 0.861 – 1.41 0.443 62 736 exclusion phecode
420.3 Endocarditis Circulatory System 0.994 0.898 – 1.1 0.904 400 4851 exclusion phecode
425 Cardiomyopathy Circulatory System 1.05 0.973 – 1.14 0.199 608 8768 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.04 0.962 – 1.13 0.308 596 8515 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.973 0.763 – 1.24 0.823 68 931 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.01 0.812 – 1.25 0.956 89 1171 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.41 1.01 – 1.98 0.0462 28 403 exclusion phecode
426 Cardiac conduction disorders Circulatory System 0.976 0.944 – 1.01 0.144 3814 46144 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 0.952 0.896 – 1.01 0.117 1125 13826 exclusion phecode
426.21 First degree AV block Circulatory System 0.963 0.881 – 1.05 0.404 527 6397 exclusion phecode
426.23 Second degree AV block Circulatory System 0.984 0.868 – 1.12 0.802 268 2957 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 0.934 0.829 – 1.05 0.259 289 3853 exclusion phecode
426.25 Other heart block Circulatory System 1.11 0.883 – 1.4 0.367 75 868 exclusion phecode
426.3 Bundle branch block Circulatory System 1.01 0.962 – 1.06 0.754 1850 22379 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.03 0.958 – 1.1 0.467 840 10047 exclusion phecode
426.32 Left bundle branch block Circulatory System 0.991 0.929 – 1.06 0.796 947 11678 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.928 0.79 – 1.09 0.359 163 1747 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.4 1.01 – 1.95 0.0423 38 404 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.965 0.912 – 1.02 0.228 1258 16287 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.957 0.901 – 1.02 0.146 1155 14951 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1 0.987 – 1.02 0.66 14168 146668 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.01 0.965 – 1.06 0.665 1998 22708 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1 0.954 – 1.06 0.862 1538 16947 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.99 0.905 – 1.08 0.828 501 6314 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.01 0.986 – 1.03 0.472 7861 90141 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.998 0.953 – 1.05 0.928 1921 22082 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.974 0.897 – 1.06 0.528 591 8043 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.93 0.802 – 1.08 0.335 190 2342 exclusion phecode
427.42 Cardiac arrest Circulatory System 0.996 0.909 – 1.09 0.93 476 6663 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.01 0.927 – 1.1 0.823 554 6551 exclusion phecode
427.6 Premature beats Circulatory System 1.05 0.943 – 1.17 0.369 333 3786 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 0.84 0.658 – 1.07 0.16 73 831 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.02 0.965 – 1.08 0.483 1309 15806 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.1 0.968 – 1.24 0.148 247 2726 exclusion phecode
427.9 Palpitations Circulatory System 0.997 0.958 – 1.04 0.881 2672 28419 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.1 1.06 – 1.15 2.6e-06 2359 36584 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.14 1.06 – 1.23 0.000336 713 13567 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.09 1.04 – 1.14 0.000216 1894 29081 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.04 0.943 – 1.14 0.454 462 5073 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 0.871 0.558 – 1.36 0.543 19 447 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.984 0.878 – 1.1 0.778 336 3689 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.21 1.03 – 1.44 0.0239 126 1424 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.07 1.01 – 1.13 0.0322 1172 13327 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.09 1 – 1.19 0.0388 569 6142 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.02 0.93 – 1.13 0.627 439 5232 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.04 0.89 – 1.22 0.6 150 1749 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.01 0.982 – 1.04 0.439 4755 58932 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.01 0.927 – 1.09 0.877 603 7600 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.07 0.899 – 1.29 0.429 123 1453 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1 0.959 – 1.04 0.965 2213 28187 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.991 0.925 – 1.06 0.797 850 11261 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.04 0.984 – 1.09 0.181 1585 19448 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.04 0.978 – 1.1 0.223 1181 14450 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.03 0.907 – 1.18 0.624 260 2923 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.06 0.978 – 1.15 0.156 632 8793 exclusion phecode
440 Atherosclerosis Circulatory System 0.997 0.918 – 1.08 0.934 602 8853 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.23 0.844 – 1.79 0.282 23 734 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.991 0.894 – 1.1 0.87 365 5154 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.02 0.861 – 1.21 0.803 137 1851 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 0.959 0.855 – 1.07 0.469 315 4192 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.897 0.753 – 1.07 0.229 140 1944 exclusion phecode
442 Other aneurysm Circulatory System 1.03 0.965 – 1.1 0.358 871 12071 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.01 0.928 – 1.09 0.893 611 9043 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.02 0.915 – 1.14 0.707 317 5469 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.37 1 – 1.87 0.0499 33 605 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.02 0.829 – 1.26 0.846 87 1106 exclusion phecode
442.4 Arterial dissection Circulatory System 1.41 1.06 – 1.88 0.0175 40 411 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.04 0.874 – 1.24 0.643 121 1440 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.02 0.972 – 1.07 0.448 1934 26801 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.05 0.976 – 1.13 0.186 753 8551 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.06 0.883 – 1.27 0.526 111 2583 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.01 0.968 – 1.06 0.555 1857 25181 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.995 0.937 – 1.06 0.86 1122 16871 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 0.992 0.9 – 1.09 0.875 423 6204 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.01 0.892 – 1.15 0.839 236 3651 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.13 1.02 – 1.25 0.0149 395 5738 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 1.18 0.967 – 1.45 0.103 81 1295 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.15 1 – 1.31 0.0493 206 2622 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.14 0.939 – 1.38 0.189 106 1715 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 0.957 0.882 – 1.04 0.286 621 8868 exclusion phecode
447.1 Stricture of artery Circulatory System 0.993 0.899 – 1.1 0.893 397 5654 exclusion phecode
448 Disease of capillaries Circulatory System 1.01 0.812 – 1.25 0.944 86 1027 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.06 0.951 – 1.17 0.309 381 5156 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.04 0.992 – 1.08 0.11 2252 27957 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.05 1 – 1.09 0.0477 2088 25960 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 0.98 0.873 – 1.1 0.74 305 4118 exclusion phecode
454 Varicose veins Circulatory System 1.01 0.984 – 1.03 0.551 8006 83774 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1 0.98 – 1.03 0.835 8287 85950 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.889 0.793 – 0.996 0.043 338 4442 exclusion phecode
455 Hemorrhoids Circulatory System 1.01 0.994 – 1.03 0.21 16487 171594 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.1 0.895 – 1.36 0.357 85 1265 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.03 0.807 – 1.32 0.798 69 663 exclusion phecode
458 Hypotension Circulatory System 1.04 0.999 – 1.07 0.0553 3122 40224 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.01 0.932 – 1.09 0.882 676 8957 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.12 0.93 – 1.34 0.237 118 1585 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.03 0.984 – 1.08 0.203 1883 24554 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.02 1 – 1.05 0.0316 8927 112673 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 0.977 0.778 – 1.23 0.844 74 993 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.03 1 – 1.05 0.0228 8849 111669 exclusion phecode
464 Acute sinusitis Respiratory 1.11 0.93 – 1.32 0.25 131 1476 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.01 0.959 – 1.07 0.689 1510 16828 exclusion phecode
465.2 Acute pharyngitis Respiratory 1.05 0.965 – 1.15 0.25 553 6196 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.02 0.843 – 1.23 0.851 110 1204 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.05 1.01 – 1.08 0.00872 3440 34890 exclusion phecode
471 Nasal polyps Respiratory 1.03 0.986 – 1.07 0.196 2359 23487 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.06 0.985 – 1.15 0.118 694 7120 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.02 0.968 – 1.07 0.491 1688 18166 exclusion phecode
473.1 Chronic laryngitis Respiratory 0.975 0.757 – 1.26 0.845 64 747 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.07 0.916 – 1.24 0.408 172 1889 exclusion phecode
473.4 Voice disturbance Respiratory 0.996 0.922 – 1.08 0.919 706 7600 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1.02 0.969 – 1.08 0.396 1361 14138 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.09 0.987 – 1.2 0.0904 426 4455 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.977 0.911 – 1.05 0.523 868 8975 exclusion phecode
475 Chronic sinusitis Respiratory 0.997 0.95 – 1.05 0.911 1842 19122 exclusion phecode
476 Allergic rhinitis Respiratory 0.953 0.884 – 1.03 0.201 804 7930 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 0.993 0.942 – 1.05 0.807 1468 16711 exclusion phecode
478 Throat pain Respiratory 1.1 0.978 – 1.25 0.111 269 2775 exclusion phecode
479 Other upper respiratory disease Respiratory 1.02 0.986 – 1.06 0.227 2863 29922 exclusion phecode
480 Pneumonia Respiratory 1.04 1.01 – 1.07 0.00634 5640 71497 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.05 1.02 – 1.09 0.00329 3627 46061 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.05 1.01 – 1.09 0.00621 3210 40833 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.01 0.763 – 1.35 0.924 46 634 exclusion phecode
480.2 Viral pneumonia Respiratory 0.776 0.55 – 1.09 0.148 39 522 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.21 0.908 – 1.6 0.197 42 678 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1 0.91 – 1.11 0.938 423 5257 exclusion phecode
481 Influenza Respiratory 1.01 0.871 – 1.17 0.906 191 2422 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.04 0.861 – 1.26 0.687 116 1405 exclusion phecode
495 Asthma Respiratory 1.02 1.01 – 1.04 0.00602 17338 187928 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1 0.855 – 1.17 0.98 164 1912 exclusion phecode
496 Chronic airway obstruction Respiratory 1.04 1.01 – 1.06 0.0125 5308 69214 exclusion phecode
496.1 Emphysema Respiratory 1.05 0.977 – 1.12 0.196 851 11564 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.03 0.976 – 1.09 0.281 1317 19655 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.03 0.973 – 1.09 0.308 1184 17996 exclusion phecode
496.3 Bronchiectasis Respiratory 0.985 0.927 – 1.05 0.628 1112 13006 exclusion phecode
497 Bronchitis Respiratory 1.01 0.901 – 1.13 0.906 345 4518 exclusion phecode
500 Lung disease due to external agents Respiratory 1.01 0.873 – 1.16 0.944 190 2563 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.12 0.817 – 1.53 0.488 37 557 exclusion phecode
500.2 Pneumoconiosis Respiratory 0.924 0.761 – 1.12 0.423 105 1418 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 0.992 0.886 – 1.11 0.894 319 4401 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.08 0.981 – 1.19 0.114 411 6032 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 0.95 0.821 – 1.1 0.495 188 3519 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.24 1.05 – 1.45 0.0103 142 2260 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.08 0.771 – 1.52 0.642 34 435 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.07 0.988 – 1.15 0.0977 651 8026 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.02 0.984 – 1.05 0.316 3569 43880 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.01 0.952 – 1.07 0.72 1123 13891 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.06 0.999 – 1.12 0.0563 1185 17527 exclusion phecode
509.1 Respiratory failure Respiratory 1.1 1.03 – 1.17 0.00484 923 13859 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.11 1.03 – 1.18 0.00422 807 12198 exclusion phecode
509.5 Respiratory arrest Respiratory 1.06 0.847 – 1.33 0.607 74 1008 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.935 0.806 – 1.09 0.379 184 2579 exclusion phecode
510 Other diseases of lung Respiratory 1.11 1.01 – 1.23 0.0271 432 5174 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.06 1.03 – 1.09 1.04e-05 5300 64335 exclusion phecode
512.1 Wheezing Respiratory 0.985 0.82 – 1.18 0.871 126 1550 exclusion phecode
512.2 Painful respiration Respiratory 1.19 0.999 – 1.41 0.0519 140 1523 exclusion phecode
512.7 Shortness of breath Respiratory 1.06 1.02 – 1.09 0.0019 3323 41531 exclusion phecode
512.8 Cough Respiratory 1.08 1.03 – 1.13 0.00288 1711 20522 exclusion phecode
512.9 Other dyspnea Respiratory 1.09 0.998 – 1.19 0.0554 532 6453 exclusion phecode
513 Respiratory abnormalities Respiratory 1.04 0.935 – 1.17 0.445 344 4276 exclusion phecode
513.3 Hypoventilation Respiratory 1.12 0.772 – 1.61 0.559 31 572 exclusion phecode
513.4 Hyperventilation Respiratory 1.02 0.877 – 1.2 0.768 173 2037 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.1 0.896 – 1.35 0.358 94 1002 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.1 1.04 – 1.16 0.000799 1360 16815 exclusion phecode
516 Abnormal sputum Respiratory 1.05 0.989 – 1.11 0.111 1221 14739 exclusion phecode
516.1 Hemoptysis Respiratory 1.05 0.987 – 1.11 0.127 1196 14347 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.03 1 – 1.06 0.0215 5349 66112 exclusion phecode
519.2 Respiratory complications Respiratory 1.15 0.985 – 1.35 0.0767 149 2197 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.03 0.998 – 1.06 0.0647 5049 62577 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.07 0.934 – 1.23 0.319 216 2189 exclusion phecode
520 Disorders of tooth development Digestive 1.02 0.969 – 1.07 0.444 1587 16220 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.925 0.643 – 1.33 0.672 33 402 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.996 0.95 – 1.04 0.854 1872 18920 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.03 0.986 – 1.08 0.17 1978 22781 exclusion phecode
521.1 Dental caries Digestive 1.03 0.985 – 1.08 0.196 1980 22849 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.03 0.969 – 1.09 0.386 1276 13546 exclusion phecode
522.5 Periapical abscess Digestive 1.04 0.971 – 1.12 0.253 834 8939 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.04 0.983 – 1.1 0.17 1208 12891 exclusion phecode
523.1 Gingivitis Digestive 1.05 0.841 – 1.31 0.66 73 795 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.05 0.982 – 1.13 0.147 859 9141 exclusion phecode
523.31 Acute periodontitis Digestive 1.03 0.938 – 1.13 0.559 499 5333 exclusion phecode
523.32 Chronic periodontitis Digestive 1.07 0.972 – 1.19 0.16 405 4296 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.11 0.973 – 1.26 0.125 250 2629 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.11 0.97 – 1.27 0.131 230 2442 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.981 0.934 – 1.03 0.432 1776 19685 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.27 0.982 – 1.63 0.0687 55 521 exclusion phecode
526 Diseases of the jaws Digestive 1.01 0.933 – 1.09 0.789 657 7001 exclusion phecode
526.1 Cysts of the jaws Digestive 0.921 0.805 – 1.05 0.234 234 2404 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.1 0.837 – 1.44 0.504 49 473 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.09 0.93 – 1.27 0.297 168 1904 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.1 0.942 – 1.29 0.228 164 1846 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 1.07 0.836 – 1.36 0.609 75 816 exclusion phecode
526.9 Jaw disease NOS Digestive 0.973 0.822 – 1.15 0.748 158 1726 exclusion phecode
527 Diseases of the salivary glands Digestive 1.04 0.948 – 1.15 0.384 455 5107 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.2 0.92 – 1.57 0.177 54 601 exclusion phecode
527.2 Sialoadenitis Digestive 1.02 0.889 – 1.16 0.823 240 2739 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 0.947 0.686 – 1.31 0.742 42 460 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 0.952 0.761 – 1.19 0.667 84 875 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.989 0.95 – 1.03 0.598 2634 28527 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.08 0.961 – 1.21 0.198 301 3440 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.05 0.928 – 1.2 0.414 248 2842 exclusion phecode
528.12 Oral aphthae Digestive 1.2 0.92 – 1.56 0.18 56 628 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.949 0.782 – 1.15 0.595 114 1341 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.881 0.706 – 1.1 0.265 90 909 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.857 0.66 – 1.11 0.25 65 703 exclusion phecode
528.5 Diseases of lips Digestive 1.02 0.925 – 1.12 0.736 474 5001 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 0.83 0.711 – 0.968 0.0177 194 2174 exclusion phecode
528.7 Sialolithiasis Digestive 0.917 0.797 – 1.05 0.223 219 2313 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.04 0.972 – 1.12 0.245 829 9018 exclusion phecode
529.1 Glossitis Digestive 1.18 1.02 – 1.36 0.0252 186 2166 exclusion phecode
530 Diseases of esophagus Digestive 1.02 1.01 – 1.04 0.000704 21728 206908 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.03 1.01 – 1.04 1e-04 20403 201209 exclusion phecode
530.11 GERD Digestive 1.03 1.01 – 1.04 0.00144 14956 164974 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.05 1.02 – 1.09 0.00422 3155 35906 exclusion phecode
530.14 Reflux esophagitis Digestive 1.04 1.01 – 1.06 0.00506 6827 75648 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.99 0.926 – 1.06 0.759 943 11936 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 0.998 0.941 – 1.06 0.954 1178 12933 exclusion phecode
530.5 Disorders of esophageal motility Digestive 0.976 0.882 – 1.08 0.641 399 4577 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.02 0.842 – 1.24 0.829 101 1024 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.955 0.829 – 1.1 0.528 215 2522 exclusion phecode
530.9 Heartburn Digestive 0.988 0.936 – 1.04 0.65 1495 15580 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.02 0.987 – 1.05 0.252 4226 49668 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.1 0.986 – 1.22 0.0881 352 4319 exclusion phecode
531.2 Gastric ulcer Digestive 1 0.964 – 1.05 0.834 2423 28820 exclusion phecode
531.3 Duodenal ulcer Digestive 1.02 0.974 – 1.07 0.386 1799 20881 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 0.985 0.864 – 1.12 0.817 239 2939 exclusion phecode
532 Dysphagia Digestive 1.01 0.983 – 1.05 0.39 4228 46637 exclusion phecode
535 Gastritis and duodenitis Digestive 1.01 0.994 – 1.02 0.256 18173 191285 exclusion phecode
535.1 Acute gastritis Digestive 1.01 0.935 – 1.09 0.844 717 8385 exclusion phecode
535.2 Atrophic gastritis Digestive 0.992 0.87 – 1.13 0.906 234 2533 exclusion phecode
535.6 Duodenitis Digestive 1.01 0.977 – 1.04 0.667 4682 54128 exclusion phecode
535.8 Other specified gastritis Digestive 1.01 0.982 – 1.04 0.485 5239 57860 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.03 0.824 – 1.29 0.794 83 858 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.1 0.945 – 1.28 0.224 175 1868 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.03 0.986 – 1.08 0.184 2045 24138 exclusion phecode
540 Appendiceal conditions Digestive 1 0.959 – 1.04 0.986 2266 23459 exclusion phecode
540.1 Appendicitis Digestive 0.998 0.955 – 1.04 0.942 2134 21972 exclusion phecode
540.11 Acute appendicitis Digestive 0.987 0.942 – 1.03 0.572 1944 19778 exclusion phecode
550 Abdominal hernia Digestive 1.01 1 – 1.02 0.0484 29510 211276 exclusion phecode
550.1 Inguinal hernia Digestive 0.992 0.972 – 1.01 0.422 10584 84628 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.03 1.01 – 1.04 0.00156 16946 174899 exclusion phecode
550.3 Femoral hernia Digestive 0.942 0.859 – 1.03 0.208 492 4835 exclusion phecode
550.4 Umbilical hernia Digestive 1.09 1.04 – 1.13 0.000138 2206 26237 exclusion phecode
550.5 Ventral hernia Digestive 1.01 0.963 – 1.05 0.754 2061 24752 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.01 0.976 – 1.05 0.478 2931 33097 exclusion phecode
555.1 Regional enteritis Digestive 1.01 0.954 – 1.08 0.658 1107 13156 exclusion phecode
555.2 Ulcerative colitis Digestive 1.01 0.962 – 1.05 0.818 2119 23491 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.02 0.917 – 1.13 0.75 381 4097 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.09 1.01 – 1.18 0.0203 693 7778 exclusion phecode
556.1 Ulceration of intestine Digestive 1.04 0.942 – 1.14 0.454 429 4916 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.997 0.86 – 1.16 0.969 198 2289 exclusion phecode
557.1 Celiac disease Digestive 0.967 0.913 – 1.02 0.258 1289 13848 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.03 1.01 – 1.05 0.00709 10139 116051 exclusion phecode
559 Ileostomy status Digestive 0.987 0.925 – 1.05 0.681 998 11716 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.03 0.987 – 1.07 0.179 2534 28294 exclusion phecode
560.1 Paralytic ileus Digestive 1.04 0.932 – 1.17 0.463 318 3637 exclusion phecode
560.2 Impaction of intestine Digestive 1.1 0.948 – 1.28 0.205 165 1951 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.952 0.872 – 1.04 0.281 547 6023 exclusion phecode
560.4 Other intestinal obstruction Digestive 1.01 0.965 – 1.05 0.717 2181 24215 exclusion phecode
561 Symptoms involving digestive system Digestive 1 0.981 – 1.02 0.991 11071 118093 exclusion phecode
561.1 Diarrhea Digestive 0.952 0.846 – 1.07 0.416 307 3348 exclusion phecode
561.2 Flatulence Digestive 1.01 0.956 – 1.08 0.637 1188 12682 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1.01 0.998 – 1.03 0.0903 17018 154122 exclusion phecode
562.1 Diverticulosis Digestive 1.01 0.997 – 1.03 0.102 16988 154070 exclusion phecode
563 Constipation Digestive 1.01 0.986 – 1.04 0.412 6720 75745 exclusion phecode
564 Functional digestive disorders Digestive 1.02 0.998 – 1.03 0.086 14222 154657 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.03 0.997 – 1.06 0.0742 4007 42741 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.03 0.965 – 1.1 0.39 1036 11923 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.01 0.988 – 1.03 0.427 9638 108537 exclusion phecode
565 Anal and rectal conditions Digestive 0.992 0.972 – 1.01 0.438 10014 106323 exclusion phecode
565.1 Anal and rectal polyp Digestive 0.991 0.963 – 1.02 0.551 4897 51529 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.05 0.959 – 1.14 0.311 519 6610 exclusion phecode
568 Other disorders of peritoneum Digestive 1.06 1.01 – 1.11 0.00953 2143 24137 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.06 1.01 – 1.11 0.0102 2045 22970 exclusion phecode
569 Other disorders of intestine Digestive 1.03 0.992 – 1.07 0.119 2686 29901 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.01 0.82 – 1.25 0.91 94 1003 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.07 0.96 – 1.2 0.211 318 3425 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.07 1.02 – 1.13 0.0104 1504 21458 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.06 0.995 – 1.13 0.0701 944 12403 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.01 0.779 – 1.32 0.922 55 810 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.14 0.949 – 1.37 0.161 105 1910 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.07 0.97 – 1.17 0.18 430 6942 exclusion phecode
571.81 Portal hypertension Digestive 1.14 0.997 – 1.3 0.0551 214 3717 exclusion phecode
572 Ascites (non malignant) Digestive 1.09 1.02 – 1.17 0.011 870 11009 exclusion phecode
573 Other disorders of liver Digestive 1.08 1.01 – 1.16 0.025 842 10720 exclusion phecode
573.2 Liver replaced by transplant Digestive 0.833 0.503 – 1.38 0.477 15 719 exclusion phecode
573.3 Hepatomegaly Digestive 1.08 0.919 – 1.27 0.357 145 2103 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1 0.915 – 1.1 0.985 498 6264 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.03 0.986 – 1.08 0.177 2045 24822 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.05 0.88 – 1.26 0.581 118 1416 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.03 1 – 1.05 0.0174 9995 116039 exclusion phecode
574.1 Cholelithiasis Digestive 1.02 0.998 – 1.04 0.0781 8674 100916 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.973 0.91 – 1.04 0.432 915 10927 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.04 1 – 1.07 0.0295 3535 40608 exclusion phecode
574.2 Calculus of bile duct Digestive 1.08 1.02 – 1.13 0.00353 1591 19218 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.04 0.986 – 1.09 0.162 1684 20184 exclusion phecode
575 Other biliary tract disease Digestive 1.04 0.996 – 1.08 0.075 2417 28197 exclusion phecode
575.1 Cholangitis Digestive 0.996 0.876 – 1.13 0.957 246 3359 exclusion phecode
575.2 Obstruction of bile duct Digestive 0.98 0.891 – 1.08 0.676 469 5513 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.985 0.879 – 1.1 0.788 329 3555 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.04 0.976 – 1.12 0.212 903 10419 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.07 0.986 – 1.16 0.109 629 7533 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.13 0.984 – 1.3 0.0822 201 2448 exclusion phecode
577 Diseases of pancreas Digestive 1.08 1.03 – 1.14 0.00299 1539 18975 exclusion phecode
577.1 Acute pancreatitis Digestive 1.1 1.04 – 1.17 0.00105 1156 14294 exclusion phecode
577.2 Chronic pancreatitis Digestive 0.966 0.858 – 1.09 0.573 289 3652 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.02 0.885 – 1.17 0.823 214 2618 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.992 – 1.03 0.273 14019 150844 exclusion phecode
578.1 Hematemesis Digestive 0.977 0.919 – 1.04 0.451 1103 13997 exclusion phecode
578.2 Blood in stool Digestive 0.994 0.944 – 1.05 0.83 1574 18437 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.02 0.997 – 1.04 0.0907 9164 96331 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.993 0.959 – 1.03 0.677 3559 38564 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.06 0.989 – 1.13 0.102 915 11399 exclusion phecode
579.2 Splenomegaly Digestive 1.14 0.985 – 1.32 0.0775 164 2991 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.998 0.938 – 1.06 0.951 1127 11968 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.12 1 – 1.24 0.0454 320 10528 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.15 1 – 1.32 0.048 189 7088 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.1 0.724 – 1.68 0.647 18 560 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.975 0.713 – 1.33 0.875 37 957 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.2 1.02 – 1.4 0.0283 140 5813 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.13 0.945 – 1.35 0.181 113 3276 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.982 0.772 – 1.25 0.885 66 1741 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.966 0.76 – 1.23 0.78 67 1798 exclusion phecode
585 Renal failure Genitourinary 1.07 1.03 – 1.12 0.000679 2224 47440 exclusion phecode
585.1 Acute renal failure Genitourinary 1.05 1 – 1.11 0.0348 1647 30586 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.08 0.987 – 1.19 0.0901 407 10013 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.11 1.01 – 1.21 0.0262 445 17878 exclusion phecode
585.31 Renal dialysis Genitourinary 1.18 0.944 – 1.48 0.146 67 3525 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.04 0.985 – 1.09 0.169 1613 23513 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.09 0.83 – 1.42 0.547 46 1460 exclusion phecode
586.11 Small kidney Genitourinary 1.17 0.875 – 1.57 0.286 38 1242 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.04 0.963 – 1.13 0.314 653 8642 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.11 0.775 – 1.6 0.557 26 569 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.03 0.938 – 1.13 0.542 473 6532 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.25 0.878 – 1.77 0.218 24 2697 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 0.987 0.644 – 1.51 0.953 21 735 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 0.879 0.648 – 1.19 0.409 42 808 exclusion phecode
590 Pyelonephritis Genitourinary 1.03 0.961 – 1.11 0.378 801 10146 exclusion phecode
591 Urinary tract infection Genitourinary 1 0.977 – 1.02 0.996 7516 88690 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.02 0.972 – 1.07 0.455 1928 21171 exclusion phecode
592.1 Cystitis Genitourinary 1.01 0.962 – 1.06 0.738 1886 20769 exclusion phecode
592.11 Acute cystitis Genitourinary 0.963 0.773 – 1.2 0.736 86 944 exclusion phecode
592.12 Chronic cystitis Genitourinary 0.977 0.897 – 1.06 0.6 577 6386 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.04 0.887 – 1.21 0.661 173 1820 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.15 0.961 – 1.36 0.129 121 1186 exclusion phecode
593 Hematuria Genitourinary 0.992 0.972 – 1.01 0.441 10355 112993 exclusion phecode
594 Urinary calculus Genitourinary 0.997 0.965 – 1.03 0.859 3976 45158 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.05 1 – 1.1 0.0463 1936 22297 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 0.927 0.84 – 1.02 0.131 430 5060 exclusion phecode
594.3 Calculus of ureter Genitourinary 1 0.953 – 1.06 0.863 1479 17012 exclusion phecode
594.8 Renal colic Genitourinary 0.976 0.923 – 1.03 0.402 1333 14789 exclusion phecode
595 Hydronephrosis Genitourinary 1.01 0.951 – 1.08 0.7 1061 13692 exclusion phecode
596 Other disorders of bladder Genitourinary 1.02 0.992 – 1.04 0.179 6147 66514 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 0.975 0.919 – 1.03 0.405 1187 12461 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1 0.943 – 1.07 0.918 1093 12035 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.02 0.978 – 1.06 0.367 2569 27514 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.01 0.969 – 1.06 0.562 2151 23144 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.15 0.841 – 1.56 0.389 38 544 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 0.987 0.946 – 1.03 0.554 2262 24317 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.878 0.745 – 1.04 0.122 158 2095 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.988 – 1.02 0.525 12379 133880 exclusion phecode
599.1 Urinary obstruction Genitourinary 1.06 0.85 – 1.33 0.596 79 1139 exclusion phecode
599.2 Retention of urine Genitourinary 1.03 0.999 – 1.07 0.0581 3915 44012 exclusion phecode
599.3 Dysuria Genitourinary 0.996 0.924 – 1.07 0.92 767 8611 exclusion phecode
599.4 Urinary incontinence Genitourinary 1 0.979 – 1.03 0.709 6225 66676 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.01 0.973 – 1.05 0.537 2659 28363 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.1 0.814 – 1.5 0.524 37 695 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 0.931 0.669 – 1.3 0.67 37 432 exclusion phecode
599.9 Other abnormality of urination Genitourinary 1.04 0.981 – 1.1 0.193 1246 13115 exclusion phecode
600 Hyperplasia of prostate Genitourinary 1 0.979 – 1.03 0.719 6386 55946 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 1.02 0.964 – 1.08 0.49 1239 13404 exclusion phecode
601.1 Prostatitis Genitourinary 1.06 0.997 – 1.14 0.0612 935 9926 exclusion phecode
601.11 Acute prostatitis Genitourinary 1.02 0.86 – 1.21 0.833 135 1527 exclusion phecode
601.12 Chronic prostatitis Genitourinary 1.04 0.959 – 1.14 0.316 548 5689 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 1.09 0.815 – 1.46 0.556 45 421 exclusion phecode
601.4 Balanoposthitis Genitourinary 1.01 0.869 – 1.17 0.905 179 1907 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.916 0.78 – 1.08 0.29 168 2013 exclusion phecode
602 Other disorders of prostate Genitourinary 1.03 0.962 – 1.11 0.377 787 8223 exclusion phecode
603 Other disorders of testis Genitourinary 0.983 0.93 – 1.04 0.555 1349 14624 exclusion phecode
603.1 Hydrocele Genitourinary 0.967 0.901 – 1.04 0.355 832 8911 exclusion phecode
604 Disorders of penis Genitourinary 1.02 0.977 – 1.07 0.355 2065 22593 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1 0.953 – 1.05 0.951 1692 18724 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 1.03 0.885 – 1.2 0.694 168 1816 exclusion phecode
608 Other disorders of male genital organs Genitourinary 1.03 0.985 – 1.08 0.189 1823 19075 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.941 0.793 – 1.12 0.492 135 1361 exclusion phecode
609.1 Infertility, male Genitourinary 1.03 0.78 – 1.37 0.813 49 503 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.924 0.757 – 1.13 0.439 99 1002 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.986 0.941 – 1.03 0.545 1972 19921 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.994 0.92 – 1.07 0.872 722 7285 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1.03 0.901 – 1.18 0.673 238 2420 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 0.963 0.839 – 1.1 0.587 235 2364 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.971 0.913 – 1.03 0.354 1121 11242 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.01 0.921 – 1.11 0.849 522 5394 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.02 0.967 – 1.09 0.41 1239 12358 exclusion phecode
611.1 Abnormal mammogram Genitourinary 1.1 0.817 – 1.49 0.517 48 428 exclusion phecode
611.3 Lump or mass in breast Genitourinary 1.03 0.971 – 1.09 0.324 1195 11952 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.01 0.93 – 1.09 0.875 675 7059 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.993 0.916 – 1.08 0.872 644 6692 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 1.16 0.9 – 1.5 0.246 62 597 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.974 0.918 – 1.03 0.389 1213 13058 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 0.964 0.88 – 1.06 0.437 519 5681 exclusion phecode
613.5 Mastodynia Genitourinary 0.792 0.584 – 1.07 0.133 52 617 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 1.01 0.923 – 1.1 0.842 543 5480 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1 0.881 – 1.14 0.964 252 2598 exclusion phecode
613.9 Breast disorder NOS Genitourinary – 154 1613 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.98 0.95 – 1.01 0.204 4555 46930 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.971 0.927 – 1.02 0.22 2029 21054 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.01 0.933 – 1.09 0.809 674 6917 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1 0.743 – 1.35 1 50 511 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.999 0.893 – 1.12 0.981 335 3472 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.03 0.909 – 1.17 0.644 284 2951 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.979 0.851 – 1.13 0.773 219 2266 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.985 0.941 – 1.03 0.528 2070 21159 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1 0.941 – 1.07 0.938 1039 10678 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.02 0.911 – 1.14 0.735 334 3428 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.957 0.88 – 1.04 0.302 632 6251 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.994 0.863 – 1.14 0.928 205 2238 exclusion phecode
615 Endometriosis Genitourinary 0.989 0.954 – 1.03 0.539 3310 33907 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.1 0.967 – 1.26 0.144 222 2413 exclusion phecode
618 Genital prolapse Genitourinary 1.01 0.992 – 1.04 0.218 8798 89103 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 1.02 0.994 – 1.05 0.129 5502 56218 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.01 0.974 – 1.04 0.733 4144 40977 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.01 0.909 – 1.12 0.835 373 3802 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.02 0.925 – 1.12 0.729 475 5087 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1.01 0.982 – 1.03 0.583 6911 70025 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.998 0.917 – 1.09 0.967 582 5971 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 0.991 0.951 – 1.03 0.652 2576 26151 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.03 0.99 – 1.08 0.13 2316 23245 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.05 0.995 – 1.11 0.0769 1403 14196 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.977 0.917 – 1.04 0.474 1065 10872 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1.11 0.845 – 1.46 0.456 51 574 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.957 0.89 – 1.03 0.239 819 8975 exclusion phecode
622 Polyp of female genital organs Genitourinary 1.01 0.983 – 1.03 0.64 8117 82727 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 1 0.978 – 1.03 0.754 5988 62113 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 1 0.961 – 1.04 0.995 2767 26862 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.02 0.952 – 1.08 0.642 1009 10437 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.96 0.881 – 1.05 0.353 582 6032 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.983 0.842 – 1.15 0.832 171 1815 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 0.959 0.853 – 1.08 0.491 320 3333 exclusion phecode
624.9 stress incontinence, female Genitourinary 1.01 0.976 – 1.04 0.678 4407 45979 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.01 0.971 – 1.06 0.539 2427 24139 exclusion phecode
625.1 Dyspareunia Genitourinary 1.04 0.97 – 1.11 0.288 990 9975 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.01 0.992 – 1.03 0.28 13511 95319 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.01 0.994 – 1.03 0.167 11804 91590 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.925 0.736 – 1.16 0.505 86 937 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 1.02 0.997 – 1.04 0.0854 8024 77074 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 1 0.95 – 1.05 0.993 1612 16218 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 1.01 0.975 – 1.05 0.529 3186 32196 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.975 0.923 – 1.03 0.356 1464 15245 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 1.2 1.01 – 1.43 0.0413 119 1378 exclusion phecode
626.8 Infertility, female Genitourinary 0.984 0.927 – 1.04 0.6 1228 12044 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.02 0.992 – 1.04 0.187 7565 79145 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 1.01 0.985 – 1.04 0.415 6532 68560 exclusion phecode
627.2 Symptomatic menopause Genitourinary 1.16 0.984 – 1.37 0.077 136 1443 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.02 0.952 – 1.1 0.533 797 8226 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 1.08 0.952 – 1.24 0.224 241 2526 exclusion phecode
628 Ovarian cyst Genitourinary 0.992 0.96 – 1.03 0.653 3823 39143 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.985 0.954 – 1.02 0.34 4734 32491 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.02 0.955 – 1.09 0.566 1022 10166 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1 0.889 – 1.13 0.974 301 2930 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1 0.955 – 1.06 0.882 1817 15648 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1 0.93 – 1.08 0.934 798 7773 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.999 0.939 – 1.06 0.964 1167 11078 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.01 0.968 – 1.06 0.575 2145 17938 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.996 0.912 – 1.09 0.938 563 5515 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.01 0.949 – 1.09 0.665 985 9563 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 0.967 0.726 – 1.29 0.819 61 625 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.973 0.909 – 1.04 0.427 981 10029 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.09 0.959 – 1.23 0.19 271 2751 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.802 0.681 – 0.946 0.00863 185 1948 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.857 0.708 – 1.04 0.113 131 1363 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 1 0.94 – 1.06 0.988 1147 11281 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.996 0.95 – 1.04 0.861 2016 18854 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.01 0.776 – 1.3 0.962 59 600 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.1 0.974 – 1.25 0.122 258 2476 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.937 0.762 – 1.15 0.536 103 1010 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.991 0.843 – 1.17 0.916 176 1744 exclusion phecode
650 Normal delivery Pregnancy Complications 1.02 0.968 – 1.07 0.496 1772 17119 exclusion phecode
651 Multiple gestation Pregnancy Complications 0.971 0.861 – 1.1 0.633 310 3126 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.976 0.925 – 1.03 0.371 1590 14954 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.999 0.941 – 1.06 0.969 1281 12312 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.39 1.08 – 1.78 0.0106 66 656 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.973 0.94 – 1.01 0.128 3940 26537 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.06 0.864 – 1.3 0.569 95 977 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.948 0.904 – 0.995 0.0299 2086 16594 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.966 0.877 – 1.06 0.487 492 4803 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.98 0.949 – 1.01 0.209 4864 26481 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1 0.957 – 1.05 0.988 2333 19087 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.827 0.684 – 1 0.0496 146 1472 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.986 0.862 – 1.13 0.833 241 2368 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.989 0.748 – 1.31 0.938 58 565 exclusion phecode
679 Complications of in utero procedures Dermatologic 1.16 0.858 – 1.56 0.342 48 490 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.04 1.01 – 1.08 0.011 4027 51507 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.935 0.838 – 1.04 0.229 353 4109 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1 0.896 – 1.12 0.993 346 3838 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.04 1.01 – 1.08 0.0251 2928 38974 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.05 1.01 – 1.09 0.0156 2932 39017 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.04 1.01 – 1.08 0.022 2904 38675 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.19 1.07 – 1.32 0.00105 358 4375 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.13 1.05 – 1.21 0.000655 807 9636 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.06 1 – 1.11 0.0398 1475 17138 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1 0.906 – 1.11 0.971 404 4550 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 0.865 0.758 – 0.988 0.0329 255 2627 exclusion phecode
687 Symptoms affecting skin Dermatologic 1.18 1.06 – 1.31 0.00229 351 3979 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.04 0.982 – 1.1 0.184 1288 15623 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.2 1.04 – 1.39 0.0109 195 2039 exclusion phecode
687.3 Changes in skin texture Dermatologic 1.16 0.914 – 1.47 0.225 71 794 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1.04 0.99 – 1.08 0.129 1962 21730 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.977 0.946 – 1.01 0.17 3950 41432 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.903 0.673 – 1.21 0.498 46 529 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.786 0.55 – 1.12 0.184 36 386 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.732 0.571 – 0.938 0.0135 80 876 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.942 0.871 – 1.02 0.131 723 7202 exclusion phecode
694.1 Vitiligo Dermatologic 0.91 0.638 – 1.3 0.6 39 445 exclusion phecode
694.2 Other dyschromia Dermatologic 0.924 0.848 – 1.01 0.0735 597 5704 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.16 0.913 – 1.47 0.225 68 847 exclusion phecode
695 Erythematous conditions Dermatologic 1 0.953 – 1.06 0.856 1513 17392 exclusion phecode
695.1 Toxic erythema Dermatologic 1.25 0.987 – 1.57 0.0638 66 829 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.03 0.837 – 1.28 0.753 87 966 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 0.967 0.702 – 1.33 0.837 36 395 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.16 0.882 – 1.53 0.286 48 516 exclusion phecode
695.3 Rosacea Dermatologic 1.05 0.922 – 1.21 0.438 224 2212 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 0.997 0.868 – 1.15 0.972 219 3148 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.841 0.656 – 1.08 0.174 71 955 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.02 0.877 – 1.19 0.788 179 2643 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 0.984 0.899 – 1.08 0.725 527 5652 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 1.01 0.863 – 1.19 0.859 146 1752 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.798 0.599 – 1.06 0.123 55 604 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 0.988 0.873 – 1.12 0.849 280 3288 exclusion phecode
696 Psoriasis and related disorders Dermatologic 0.97 0.917 – 1.03 0.297 1320 16391 exclusion phecode
696.4 Psoriasis Dermatologic 0.977 0.922 – 1.03 0.419 1285 16044 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 0.978 0.916 – 1.05 0.515 954 12132 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 1.01 0.921 – 1.12 0.781 450 5291 exclusion phecode
697 Sarcoidosis Dermatologic 1.14 1.01 – 1.28 0.0352 268 4024 exclusion phecode
698 Pruritus and related conditions Dermatologic 0.987 0.904 – 1.08 0.761 550 5719 exclusion phecode
700 Corns and callosities Dermatologic 0.977 0.84 – 1.14 0.765 185 2154 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.02 0.98 – 1.05 0.392 3312 34327 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.797 0.594 – 1.07 0.129 54 590 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.02 0.969 – 1.07 0.477 1716 17453 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 1.26 0.926 – 1.73 0.139 38 428 exclusion phecode
701.4 Keloid scar Dermatologic 0.978 0.834 – 1.15 0.781 162 1675 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 1.06 0.946 – 1.18 0.326 338 3396 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 0.903 0.699 – 1.17 0.437 64 767 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1 0.968 – 1.03 0.965 3821 38063 exclusion phecode
702.1 Actinic keratosis Dermatologic 1 0.953 – 1.05 0.971 1753 17669 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 0.999 0.957 – 1.04 0.976 2208 21594 exclusion phecode
703 Diseases of nail, NOS Dermatologic 0.995 0.868 – 1.14 0.94 230 2525 exclusion phecode
703.1 Ingrowing nail Dermatologic 1.12 1.04 – 1.22 0.00357 620 7152 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 1.04 1.01 – 1.08 0.0131 3837 39206 exclusion phecode
704.1 Alopecia Dermatologic 1 0.801 – 1.25 0.997 83 992 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.09 0.848 – 1.4 0.506 58 561 exclusion phecode
705 Disorders of sweat glands Dermatologic 1.05 0.885 – 1.25 0.575 139 1822 exclusion phecode
705.3 Hidradenitis Dermatologic 0.994 0.823 – 1.2 0.946 114 1494 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.14 1.03 – 1.26 0.0135 361 4228 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1.04 1.01 – 1.06 0.00654 6063 61421 exclusion phecode
706.1 Acne Dermatologic 1.34 1.04 – 1.72 0.0244 57 622 exclusion phecode
706.2 Sebaceous cyst Dermatologic 1.03 1 – 1.05 0.042 6421 64821 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.07 1 – 1.15 0.0431 823 13259 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.04 0.948 – 1.15 0.39 426 6025 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 1.01 0.969 – 1.06 0.575 2182 24985 exclusion phecode
709.2 Sicca syndrome Dermatologic 1.12 0.989 – 1.26 0.0759 260 3817 exclusion phecode
709.3 Systemic sclerosis Dermatologic 1.1 0.894 – 1.35 0.369 90 1293 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.38 1.01 – 1.88 0.0409 32 505 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.986 0.939 – 1.03 0.554 1812 19648 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.08 0.965 – 1.22 0.174 290 4237 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.06 0.94 – 1.2 0.332 266 3944 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.1 0.9 – 1.35 0.351 99 1413 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.05 0.903 – 1.22 0.53 176 2796 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 1.15 1.02 – 1.3 0.0279 246 3048 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.18 1.02 – 1.36 0.0274 183 2351 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.33 1.01 – 1.75 0.046 46 569 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.12 0.882 – 1.42 0.352 65 1078 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.18 0.748 – 1.85 0.482 15 445 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.03 0.993 – 1.07 0.104 2698 35492 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.02 0.984 – 1.07 0.238 2421 32196 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.986 0.925 – 1.05 0.664 1023 12060 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.955 0.75 – 1.22 0.709 72 897 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.05 0.944 – 1.16 0.391 379 4404 exclusion phecode
716 Other arthropathies Musculoskeletal 1.03 1.02 – 1.05 1.23e-06 23477 196989 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.05 1.01 – 1.1 0.0258 2074 25167 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.03 1.01 – 1.05 0.00345 9596 111168 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.03 1.02 – 1.05 4.7e-06 22494 194363 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.05 0.966 – 1.14 0.257 598 7700 exclusion phecode
720 Spinal stenosis Musculoskeletal 1.05 1 – 1.09 0.0408 2203 25800 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1.01 0.984 – 1.04 0.368 4838 55921 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.02 0.98 – 1.05 0.393 3110 35929 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.906 0.742 – 1.11 0.333 109 1333 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 1.02 0.885 – 1.17 0.804 211 2495 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.03 1.01 – 1.06 0.0107 6074 66959 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.996 0.895 – 1.11 0.939 377 3878 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.06 1.01 – 1.11 0.0195 1811 21082 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1 0.745 – 1.35 0.987 47 524 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.05 1.01 – 1.09 0.016 2998 32921 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.09 0.973 – 1.21 0.139 335 3762 exclusion phecode
723.1 Torticollis Musculoskeletal 1.12 0.904 – 1.39 0.295 79 818 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.03 0.98 – 1.09 0.222 1386 15228 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 0.953 0.847 – 1.07 0.419 307 3198 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.947 0.843 – 1.07 0.366 311 3212 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.16 0.849 – 1.57 0.358 39 439 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.05 0.991 – 1.12 0.0933 1061 11786 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.01 0.987 – 1.03 0.494 10176 107805 exclusion phecode
726.1 Enthesopathy Musculoskeletal 1.01 0.987 – 1.04 0.347 6550 69785 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.914 0.803 – 1.04 0.173 266 2591 exclusion phecode
726.3 Bursitis Musculoskeletal 0.996 0.915 – 1.08 0.918 564 6223 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.01 0.979 – 1.04 0.606 5229 54739 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.985 0.939 – 1.03 0.537 1873 20440 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 1.12 0.894 – 1.4 0.325 77 733 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.997 0.955 – 1.04 0.893 2325 23560 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 1.11 1 – 1.23 0.0423 375 4137 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.996 0.873 – 1.14 0.948 242 2529 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.997 0.81 – 1.23 0.978 99 1022 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1 0.962 – 1.04 0.922 2465 24188 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.11 0.989 – 1.24 0.0781 308 3266 exclusion phecode
728.7 Fasciitis Musculoskeletal 1.01 0.968 – 1.05 0.695 2559 25266 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.999 0.958 – 1.04 0.959 2348 22728 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.04 1 – 1.07 0.0307 3620 44027 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.02 0.938 – 1.1 0.689 655 7817 exclusion phecode
729.3 Panniculitis Musculoskeletal 1 0.792 – 1.26 1 77 746 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.989 0.852 – 1.15 0.887 196 2119 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.986 0.846 – 1.15 0.852 186 2012 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.965 0.862 – 1.08 0.538 344 3573 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.876 0.736 – 1.04 0.137 145 1541 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.06 0.784 – 1.43 0.707 43 451 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.01 0.951 – 1.07 0.763 1196 13157 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1 0.875 – 1.15 0.946 225 2302 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.05 0.934 – 1.17 0.441 316 3935 exclusion phecode
733.6 Costochondritis Musculoskeletal 1.06 0.864 – 1.3 0.574 85 939 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.992 0.922 – 1.07 0.83 820 9217 exclusion phecode
733.9 Chondromalacia Musculoskeletal 0.815 0.654 – 1.02 0.0695 93 930 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1.01 0.983 – 1.03 0.574 6982 71984 exclusion phecode
735.1 Flat foot Musculoskeletal 1.05 0.876 – 1.25 0.611 122 1423 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 1.02 0.983 – 1.05 0.329 3551 37254 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.04 0.987 – 1.1 0.132 1329 14089 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.997 0.938 – 1.06 0.929 1142 11378 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.01 0.979 – 1.04 0.591 4947 50311 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 1.02 0.958 – 1.09 0.52 1006 11671 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.03 0.884 – 1.21 0.67 171 1820 exclusion phecode
737 Curvature of spine Musculoskeletal 0.979 0.906 – 1.06 0.602 691 8211 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.979 0.903 – 1.06 0.608 649 7702 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1 0.945 – 1.06 0.954 1249 13821 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.95 0.888 – 1.02 0.135 955 10770 exclusion phecode
739 Contracture of joint Musculoskeletal 1.03 0.915 – 1.15 0.658 306 3667 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.03 1.02 – 1.05 2.79e-05 17376 166682 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.03 1.01 – 1.05 0.00276 11040 119049 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.03 1 – 1.06 0.0419 5522 62406 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1 0.879 – 1.14 0.964 227 2490 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.03 0.921 – 1.15 0.634 343 4215 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.04 1.02 – 1.07 0.000445 7456 87250 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.05 1.01 – 1.1 0.0209 2324 25926 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 1.22 0.956 – 1.56 0.109 68 725 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.08 0.985 – 1.19 0.1 450 4582 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 1.1 0.887 – 1.37 0.383 79 1092 exclusion phecode
741.4 Joint effusions Musculoskeletal 1.06 0.985 – 1.13 0.122 843 10050 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.29 1.01 – 1.63 0.0385 68 795 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.867 0.623 – 1.21 0.396 37 413 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.04 0.994 – 1.09 0.092 2079 21769 exclusion phecode
742.1 Loose body in joint Musculoskeletal 1.15 1.01 – 1.31 0.0362 236 2417 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.959 0.758 – 1.21 0.727 75 790 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.14 1.02 – 1.27 0.0187 350 3839 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 1.01 0.958 – 1.07 0.685 1489 15364 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.02 0.992 – 1.05 0.156 4923 54050 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.01 0.982 – 1.05 0.392 4147 45488 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.01 0.979 – 1.05 0.471 3611 39824 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 1.03 0.92 – 1.15 0.622 319 3471 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1 0.889 – 1.13 0.947 281 3692 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.09 1 – 1.18 0.0438 583 6068 exclusion phecode
745 Pain in joint Musculoskeletal 1.01 0.981 – 1.04 0.533 5204 58798 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.983 0.934 – 1.03 0.495 1632 19231 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.979 0.929 – 1.03 0.436 1509 17983 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.95 0.856 – 1.05 0.332 413 4430 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.885 0.745 – 1.05 0.162 152 1731 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.992 0.929 – 1.06 0.822 929 11802 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.03 0.86 – 1.23 0.748 116 1230 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.33 0.96 – 1.83 0.087 35 360 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.18 1.03 – 1.35 0.0164 226 2300 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 0.988 0.895 – 1.09 0.81 420 4857 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.997 0.868 – 1.15 0.972 206 2222 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.9 0.746 – 1.08 0.269 122 1296 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.02 0.886 – 1.17 0.795 210 2597 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.997 0.849 – 1.17 0.967 158 1622 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.931 0.696 – 1.24 0.629 46 877 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.969 0.905 – 1.04 0.378 905 11418 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.923 0.842 – 1.01 0.0899 537 5406 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.975 0.874 – 1.09 0.657 372 3782 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.857 0.724 – 1.01 0.0733 155 1519 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.04 0.936 – 1.15 0.483 370 6043 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 1.23 1.04 – 1.45 0.0133 133 3003 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.982 0.848 – 1.14 0.812 186 2457 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.928 0.809 – 1.07 0.289 231 2580 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.05 0.901 – 1.23 0.528 180 2025 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.999 0.841 – 1.19 0.993 145 1665 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.693 0.506 – 0.948 0.0217 54 593 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.08 0.865 – 1.36 0.486 81 953 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.02 0.766 – 1.37 0.868 47 581 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.944 0.745 – 1.2 0.63 72 859 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.04 0.923 – 1.17 0.532 306 3285 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.08 0.913 – 1.27 0.381 153 1554 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.905 0.74 – 1.11 0.333 114 1299 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.839 0.652 – 1.08 0.171 76 870 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.972 0.88 – 1.07 0.573 414 4400 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.984 0.752 – 1.29 0.909 60 635 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.01 0.896 – 1.13 0.909 297 3254 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.21 0.989 – 1.49 0.063 88 1308 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.11 0.811 – 1.51 0.521 36 648 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.966 0.812 – 1.15 0.697 133 1586 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.02 0.805 – 1.3 0.855 64 704 exclusion phecode
760 Back pain Symptoms 1.03 1 – 1.05 0.028 7241 82599 exclusion phecode
761 Cervicalgia Symptoms 0.983 0.927 – 1.04 0.575 1226 13386 exclusion phecode
764 Sciatica Symptoms 1.04 0.991 – 1.1 0.107 1561 17542 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.08 1 – 1.16 0.0436 749 8615 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.13 1.02 – 1.24 0.0145 414 4712 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.961 0.881 – 1.05 0.365 563 6326 exclusion phecode
771.1 Swelling of limb Symptoms 1.04 0.999 – 1.08 0.054 2688 33176 exclusion phecode
772 Symptoms of the muscles Symptoms 1.04 0.943 – 1.15 0.435 423 4807 exclusion phecode
773 Pain in limb Symptoms 1.01 0.98 – 1.05 0.468 3953 45671 exclusion phecode
780 Hypothermia/Chills Symptoms 0.989 0.806 – 1.21 0.917 97 1231 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.07 1.01 – 1.14 0.0159 1200 13658 exclusion phecode
782.3 Edema Symptoms 1.05 0.976 – 1.13 0.195 745 11377 exclusion phecode
782.6 Pallor and flushing Symptoms 1.11 0.926 – 1.33 0.257 119 1247 exclusion phecode
783 Fever of unknown origin Symptoms 1.04 0.998 – 1.08 0.0629 2439 28217 exclusion phecode
785 Abdominal pain Symptoms 1.01 1 – 1.03 0.0259 28423 225671 exclusion phecode
788 Syncope and collapse Symptoms 0.996 0.969 – 1.02 0.779 5658 63507 exclusion phecode
789 Nausea and vomiting Symptoms 1.02 0.994 – 1.04 0.134 7405 85578 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.03 0.838 – 1.28 0.752 87 1038 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 0.834 0.59 – 1.18 0.302 38 573 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.02 0.989 – 1.06 0.186 3644 41750 exclusion phecode
791 Gangrene Symptoms 1.09 0.966 – 1.24 0.156 244 3880 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1.01 0.796 – 1.29 0.908 76 727 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.959 0.769 – 1.2 0.711 85 945 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 0.973 0.871 – 1.09 0.624 349 3993 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.923 0.744 – 1.14 0.464 96 1018 exclusion phecode
797 Shock Symptoms 1.13 0.909 – 1.4 0.274 77 1011 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.04 0.783 – 1.37 0.799 46 639 exclusion phecode
798 Malaise and fatigue Symptoms 1.01 0.968 – 1.06 0.596 2176 24992 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1.01 0.919 – 1.12 0.785 447 4590 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.02 0.987 – 1.05 0.271 4863 50960 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1 0.945 – 1.06 0.931 1178 12464 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.16 0.96 – 1.4 0.125 105 1222 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.07 1.02 – 1.12 0.011 1569 16175 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 1.07 0.978 – 1.16 0.146 532 5519 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.02 0.969 – 1.07 0.458 1561 16475 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.04 0.983 – 1.1 0.172 1313 13664 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.02 0.934 – 1.12 0.614 488 5176 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 1.01 0.987 – 1.04 0.315 6088 61074 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1.03 0.971 – 1.1 0.312 1139 12241 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.02 0.989 – 1.06 0.202 3930 38861 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.998 0.939 – 1.06 0.961 1111 10928 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.995 0.955 – 1.04 0.828 2464 24889 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.01 0.941 – 1.08 0.862 927 9901 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 0.96 0.878 – 1.05 0.379 526 5437 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.02 0.955 – 1.09 0.521 887 9451 exclusion phecode
817 Concussion Injuries & Poisonings 1.05 0.905 – 1.22 0.508 180 1822 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.08 0.968 – 1.21 0.168 333 3559 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.03 0.986 – 1.08 0.185 2173 22133 exclusion phecode
823 Torus fracture Injuries & Poisonings 1.07 1.01 – 1.13 0.0186 1226 12588 exclusion phecode
830 Dislocation Injuries & Poisonings 0.972 0.923 – 1.02 0.295 1519 15494 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 1.02 0.999 – 1.04 0.0592 10995 112652 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 1.01 0.908 – 1.13 0.831 366 3840 exclusion phecode
840 Sprains and strains Injuries & Poisonings 1.02 0.914 – 1.13 0.762 358 3560 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.02 0.982 – 1.05 0.358 3428 38344 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.951 0.767 – 1.18 0.644 94 1115 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 0.985 0.871 – 1.11 0.807 276 3525 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1 0.936 – 1.07 0.935 866 12213 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.976 0.905 – 1.05 0.537 734 8833 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.965 0.921 – 1.01 0.131 1936 22544 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.02 0.978 – 1.07 0.307 2013 23394 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.34 0.993 – 1.82 0.0557 40 530 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.02 0.973 – 1.06 0.487 2338 25149 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.963 0.827 – 1.12 0.63 183 1967 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 1.06 0.881 – 1.26 0.556 125 1439 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.03 0.985 – 1.08 0.187 1943 20767 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.999 0.847 – 1.18 0.99 148 1535 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.761 0.562 – 1.03 0.0774 48 511 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.02 0.978 – 1.06 0.411 2888 29962 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.17 0.864 – 1.58 0.311 41 369 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.1 0.848 – 1.44 0.462 62 656 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.09 0.906 – 1.3 0.371 118 1315 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.01 0.909 – 1.13 0.81 349 3368 exclusion phecode
873 Broken tooth Injuries & Poisonings 1.11 0.949 – 1.31 0.186 158 1673 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.12 0.917 – 1.38 0.262 87 1237 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.07 0.887 – 1.3 0.47 113 1185 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.03 0.963 – 1.1 0.393 910 9756 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.02 0.986 – 1.07 0.211 2732 30875 exclusion phecode
916 Contusion Injuries & Poisonings 1.04 0.975 – 1.11 0.226 958 10427 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.916 0.764 – 1.1 0.345 134 1399 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.04 0.916 – 1.18 0.557 250 2641 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.943 0.807 – 1.1 0.466 168 1712 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.05 0.993 – 1.11 0.0861 1350 15276 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.11 0.947 – 1.31 0.194 152 1568 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.12 0.878 – 1.43 0.362 62 732 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.998 0.892 – 1.12 0.966 333 4070 exclusion phecode
947 Urticaria Injuries & Poisonings 1.03 0.908 – 1.17 0.622 249 2770 exclusion phecode
949 Allergies, other Injuries & Poisonings 0.976 0.863 – 1.11 0.705 280 3065 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.955 0.847 – 1.08 0.448 296 3088 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.01 0.857 – 1.18 0.931 158 1935 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.972 0.865 – 1.09 0.635 310 3587 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.05 0.749 – 1.48 0.763 30 385 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.69 0.503 – 0.946 0.0214 51 506 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.02 1.01 – 1.04 0.00865 12268 135935 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.03 1.01 – 1.05 0.00469 10735 118729 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.02 0.898 – 1.16 0.744 253 3125 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.937 0.859 – 1.02 0.143 575 6701 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.1 0.957 – 1.27 0.176 192 2752 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.13 0.98 – 1.3 0.0928 188 2693 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.96 0.811 – 1.14 0.637 148 1787 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.16 0.981 – 1.38 0.0811 121 1978 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.22 1.02 – 1.45 0.0265 116 1929 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.998 0.966 – 1.03 0.896 3968 45867 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.03 0.957 – 1.11 0.421 758 8661 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.11 0.992 – 1.24 0.068 334 3867 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.913 0.8 – 1.04 0.174 253 2948 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.06 0.95 – 1.18 0.301 347 4037 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.07 0.97 – 1.19 0.169 404 4411 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.02 0.967 – 1.08 0.42 1325 15609 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.936 0.772 – 1.13 0.496 121 1510 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.05 0.894 – 1.23 0.556 157 2049 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.06 0.802 – 1.4 0.686 51 670 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.38 1.1 – 1.74 0.00605 66 835 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.17 0.858 – 1.6 0.317 35 711 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.82 0.592 – 1.14 0.233 41 509 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.02 0.728 – 1.42 0.916 39 449 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.979 0.824 – 1.16 0.806 143 1740 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1 0.911 – 1.1 0.949 458 5403 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.949 0.795 – 1.13 0.558 136 1611 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.06 0.788 – 1.42 0.706 45 460 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.07 0.834 – 1.38 0.577 61 764 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.892 0.71 – 1.12 0.33 86 877 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.946 0.717 – 1.25 0.697 53 617 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1 0.957 – 1.05 0.94 2013 21824 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.03 0.977 – 1.08 0.288 1560 21063 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.03 0.977 – 1.08 0.288 1560 21063 exclusion phecode
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