Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Vitamin B12 Michigan Genomics Initiative Freeze 3 (MGI) PheWAS analysis

Vitamin B12 — Michigan Genomics Initiative Freeze 3 (MGI) PRS PheWAS

PRS model
PRS ID exprsweb-vitamin-b12-wood-et-al-2013-1000g-plink-mgi-freeze3-20211120Legacy PLINKC+T (GT)Large GWAS

Evaluation cohort: Michigan Genomics Initiative Freeze 3 (MGI).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: normal-range subset (200-900 pg/ml).

For this ExPRS, the exclusion sensitivity scan keeps only the study's normal-range subset for Vitamin B12 (200-900 pg/ml) before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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Signal overview

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102 rows visible 15 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.01 0.976 – 1.05 0.503 3004 29292 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.01 0.958 – 1.07 0.654 1322 13162 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.01 0.952 – 1.08 0.697 1046 10455 all phecode
008.6 Viral Enteritis Infectious Diseases 1.05 0.974 – 1.13 0.21 770 7676 all phecode
010 Tuberculosis Infectious Diseases 1 0.887 – 1.15 0.942 244 2425 all phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.894 0.733 – 1.11 0.28 86 855 all phecode
038 Septicemia Infectious Diseases 1.03 0.986 – 1.07 0.194 2582 24779 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.01 0.929 – 1.11 0.776 568 5629 all phecode
038.2 Gram positive septicemia Infectious Diseases 0.934 0.819 – 1.07 0.319 235 2350 all phecode
038.3 Bacteremia Infectious Diseases 1.06 0.996 – 1.13 0.0721 1210 12079 all phecode
041 Bacterial infection NOS Infectious Diseases 1.01 0.985 – 1.04 0.376 5750 38799 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.03 0.98 – 1.09 0.24 1707 16977 all phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1 0.937 – 1.08 0.934 920 9192 all phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.08 1 – 1.17 0.047 783 7812 all phecode
041.2 Streptococcus infection Infectious Diseases 1.02 0.972 – 1.08 0.39 1632 16287 all phecode
041.21 Rheumatic fever / chorea Infectious Diseases 0.95 0.838 – 1.08 0.428 257 2554 all phecode
041.4 E. coli Infectious Diseases 1.02 0.965 – 1.09 0.439 1175 11680 all phecode
041.8 H. pylori Infectious Diseases 0.971 0.852 – 1.11 0.658 257 2521 all phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.06 0.956 – 1.19 0.269 387 3864 all phecode
053 Herpes zoster Infectious Diseases 0.955 0.908 – 1.01 0.0769 1560 15184 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.944 0.825 – 1.09 0.403 220 2169 all phecode
054 Herpes simplex Infectious Diseases 1.01 0.956 – 1.06 0.81 1593 15600 all phecode
070 Viral hepatitis Infectious Diseases 1.03 0.955 – 1.11 0.48 829 8280 all phecode
070.1 Viral hepatitis A Infectious Diseases 0.963 0.789 – 1.2 0.719 87 860 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.07 0.93 – 1.24 0.344 215 2138 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.04 0.948 – 1.14 0.424 528 5280 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.02 0.881 – 1.2 0.777 197 1964 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.05 0.987 – 1.12 0.128 1145 11381 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.06 0.893 – 1.27 0.514 145 1450 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.988 0.816 – 1.21 0.906 117 1163 all phecode
078 Viral warts & HPV Infectious Diseases 1.02 0.983 – 1.06 0.31 3434 29624 all phecode
079 Viral infection Infectious Diseases 1.02 0.995 – 1.05 0.115 6664 35342 all phecode
079.1 Varicella infection Infectious Diseases 1.02 0.982 – 1.05 0.364 3793 31251 all phecode
079.2 Infectious mononucleosis Infectious Diseases 0.972 0.87 – 1.09 0.625 283 2723 all phecode
079.9 Viremia, NOS Infectious Diseases 1.02 0.953 – 1.1 0.533 838 8253 all phecode
080 Postoperative infection Infectious Diseases 0.998 0.96 – 1.04 0.941 2619 26065 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.03 0.979 – 1.09 0.249 1589 15884 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.01 0.944 – 1.08 0.836 965 9630 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.01 0.97 – 1.04 0.781 3544 30054 all phecode
110.1 Dermatophytosis Infectious Diseases 1.01 0.971 – 1.05 0.693 3241 27244 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.01 0.959 – 1.05 0.832 2044 16765 all phecode
110.12 Althete's foot Infectious Diseases 0.985 0.92 – 1.06 0.656 899 8043 all phecode
110.13 Dermatophytosis of the body Infectious Diseases 0.998 0.929 – 1.08 0.96 790 7827 all phecode
110.2 Dermatomycoses Infectious Diseases 0.954 0.866 – 1.05 0.346 398 3971 all phecode
112 Candidiasis Infectious Diseases 0.994 0.961 – 1.03 0.739 3685 30495 all phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.03 0.948 – 1.11 0.524 682 6732 all phecode
117 Mycoses Infectious Diseases 1 0.926 – 1.09 0.934 608 6069 all phecode
117.1 Histoplasmosis Infectious Diseases 1.07 0.854 – 1.38 0.564 81 801 all phecode
117.4 Aspergillosis Infectious Diseases 0.9 0.775 – 1.06 0.18 140 1387 all phecode
130 Spirochetal infection Infectious Diseases 0.848 0.728 – 0.994 0.0364 168 1677 all phecode
130.1 Lyme disease Infectious Diseases 0.859 0.72 – 1.04 0.0974 116 1160 all phecode
131 Protozoan infection Infectious Diseases 1.42 1.05 – 1.95 0.0225 61 610 all phecode
132 Infestation (lice, mites) Infectious Diseases 0.925 0.807 – 1.07 0.27 195 1948 all phecode
134 Helminthiases Infectious Diseases 1.05 0.86 – 1.31 0.643 83 812 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1.15 0.884 – 1.55 0.308 53 513 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.02 0.98 – 1.05 0.375 3279 32486 all phecode
145 Cancer of mouth Neoplasms 0.966 0.918 – 1.02 0.2 1481 14725 all phecode
145.1 Cancer of lip Neoplasms 0.983 0.793 – 1.24 0.877 76 750 all phecode
145.2 Cancer of tongue Neoplasms 0.986 0.912 – 1.07 0.729 645 6430 all phecode
145.3 Cancer of major salivary glands Neoplasms 0.926 0.837 – 1.03 0.145 361 3597 all phecode
145.4 Cancer of the gums Neoplasms 1.09 0.928 – 1.29 0.313 166 1632 all phecode
145.5 Cancer of the mouth floor Neoplasms 0.877 0.768 – 1.01 0.056 206 2048 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.991 0.936 – 1.05 0.755 1290 12873 all phecode
149.1 Cancer of oropharynx Neoplasms 0.979 0.876 – 1.1 0.718 350 3499 all phecode
149.2 Cancer of nasopharynx Neoplasms 0.941 0.762 – 1.18 0.579 100 1000 all phecode
149.3 Cancer of hypopharynx Neoplasms 0.829 0.682 – 1.02 0.067 82 819 all phecode
149.4 Cancer of larynx Neoplasms 1.03 0.934 – 1.15 0.519 386 3857 all phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 0.993 0.911 – 1.09 0.878 552 5505 all phecode
149.9 Cancer of of nasal cavities Neoplasms 0.976 0.855 – 1.12 0.723 240 2398 all phecode
150 Cancer of esophagus Neoplasms 0.965 0.876 – 1.07 0.475 433 4315 all phecode
151 Cancer of stomach Neoplasms 0.966 0.882 – 1.06 0.453 498 4962 all phecode
153 Colorectal cancer Neoplasms 1 0.948 – 1.06 0.985 1458 14383 all phecode
153.2 Colon cancer Neoplasms 0.999 0.941 – 1.06 0.984 1160 11472 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.06 0.985 – 1.15 0.12 815 8093 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.925 0.849 – 1.01 0.0759 511 5097 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.996 0.891 – 1.12 0.938 344 3433 all phecode
157 Pancreatic cancer Neoplasms 1 0.917 – 1.1 0.933 503 5005 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.977 0.929 – 1.03 0.361 1623 15759 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.01 0.964 – 1.06 0.629 1818 17869 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.978 0.86 – 1.12 0.741 221 2206 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.08 0.919 – 1.29 0.353 158 1578 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.97 0.862 – 1.1 0.62 293 2920 all phecode
164 Cancer of intrathoracic organs Neoplasms 1 0.833 – 1.22 0.981 133 1324 all phecode
165 Cancer within the respiratory system Neoplasms 1 0.949 – 1.06 0.904 1336 13340 all phecode
165.1 Cancer of bronchus; lung Neoplasms 0.985 0.925 – 1.05 0.638 1057 10552 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.978 0.933 – 1.03 0.374 1792 17850 all phecode
170.1 Bone cancer Neoplasms 1.03 0.959 – 1.12 0.391 773 7690 all phecode
170.2 Cancer of connective tissue Neoplasms 0.962 0.91 – 1.02 0.178 1266 12632 all phecode
172 Skin cancer Neoplasms 0.946 0.923 – 0.97 9.16e-06 8608 33186 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.953 0.926 – 0.982 0.0015 5330 30106 all phecode
172.11 Melanomas of skin Neoplasms 0.969 0.933 – 1.01 0.096 3100 25064 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.941 0.916 – 0.966 6.12e-06 7095 30462 all phecode
172.21 Basal cell carcinoma Neoplasms 0.952 0.919 – 0.986 0.00603 3690 23868 all phecode
172.22 Squamous cell carcinoma Neoplasms 0.945 0.905 – 0.987 0.00975 2414 17683 all phecode
172.3 Carcinoma in situ of skin Neoplasms 0.944 0.896 – 0.996 0.0338 1482 12326 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.97 0.927 – 1.02 0.189 1997 18755 all phecode
174 Breast cancer Neoplasms 0.994 0.957 – 1.03 0.765 3186 15514 all phecode
174.1 Breast cancer [female] Neoplasms 0.992 0.954 – 1.03 0.688 3036 14701 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.995 0.956 – 1.04 0.806 2991 14639 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.92 0.811 – 1.05 0.2 233 2307 all phecode
175 Acquired absence of breast Neoplasms 0.998 0.933 – 1.07 0.947 919 8920 all phecode
180 Cervical cancer and dysplasia Neoplasms 0.967 0.918 – 1.02 0.209 1431 12185 all phecode
180.1 Cervical cancer Neoplasms 0.956 0.879 – 1.04 0.295 500 4982 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.986 0.928 – 1.05 0.648 1048 9323 all phecode
182 Malignant neoplasm of uterus Neoplasms 1.04 0.967 – 1.13 0.285 765 7613 all phecode
184 Cancer of other female genital organs Neoplasms 1 0.945 – 1.07 0.931 1191 11592 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.991 0.912 – 1.08 0.83 573 5719 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.01 0.92 – 1.12 0.787 432 4309 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.99 0.913 – 1.08 0.808 608 6057 all phecode
185 Cancer of prostate Neoplasms 0.996 0.954 – 1.04 0.854 2901 10342 all phecode
187 Cancer of other male genital organs Neoplasms 0.94 0.848 – 1.05 0.247 339 3384 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.956 0.809 – 1.14 0.608 115 1141 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.937 0.818 – 1.09 0.369 183 1830 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.943 0.706 – 1.29 0.693 57 562 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1 0.965 – 1.04 0.885 2923 23541 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.01 0.959 – 1.07 0.661 1450 14437 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.01 0.956 – 1.08 0.639 1267 12655 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.02 0.889 – 1.17 0.829 237 2347 all phecode
189.2 Cancer of bladder Neoplasms 0.994 0.946 – 1.04 0.802 1783 15224 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.992 0.943 – 1.04 0.76 1657 14178 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.945 0.874 – 1.02 0.154 678 6586 all phecode
190 Cancer of eye Neoplasms 1.04 0.877 – 1.24 0.672 138 1374 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.963 0.906 – 1.02 0.222 1078 10771 all phecode
191.1 Cancer of brain and nervous system Neoplasms 0.958 0.889 – 1.03 0.265 706 7052 all phecode
191.11 Cancer of brain Neoplasms 0.946 0.873 – 1.03 0.189 600 5996 all phecode
193 Thyroid cancer Neoplasms 1.02 0.955 – 1.09 0.556 945 9393 all phecode
194 Cancer of other endocrine glands Neoplasms 1 0.923 – 1.09 0.953 579 5759 all phecode
195 Cancer, suspected or other Neoplasms 0.976 0.955 – 0.996 0.0192 16962 26401 all phecode
195.1 Malignant neoplasm, other Neoplasms 0.975 0.955 – 0.996 0.0181 16670 26384 all phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 0.976 0.919 – 1.04 0.447 1103 9766 all phecode
196 Radiotherapy Neoplasms 0.996 0.955 – 1.04 0.87 2427 17006 all phecode
197 Chemotherapy Neoplasms 0.992 0.962 – 1.02 0.615 4952 23797 all phecode
198 Secondary malignant neoplasm Neoplasms 0.98 0.952 – 1.01 0.187 5801 23481 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.984 0.95 – 1.02 0.356 3677 21489 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.992 0.933 – 1.06 0.797 1072 10334 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.992 0.926 – 1.06 0.82 866 8538 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1 0.933 – 1.08 0.918 767 7558 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.942 0.871 – 1.02 0.136 640 6338 all phecode
198.6 Secondary malignancy of bone Neoplasms 0.952 0.89 – 1.02 0.158 866 8307 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.874 0.792 – 0.969 0.00885 336 3253 all phecode
199 Neoplasm of uncertain behavior Neoplasms 0.976 0.948 – 1 0.0982 5693 25767 all phecode
199.4 Neurofibromatosis Neoplasms 1.03 0.844 – 1.29 0.782 88 880 all phecode
200 Myeloproliferative disease Neoplasms 1.01 0.947 – 1.07 0.828 1113 11098 all phecode
200.1 Polycythemia vera Neoplasms 1.11 0.961 – 1.28 0.168 231 2310 all phecode
201 Hodgkin's disease Neoplasms 0.911 0.792 – 1.06 0.201 172 1705 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.02 0.971 – 1.08 0.387 1559 15571 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.03 0.977 – 1.1 0.254 1329 13268 all phecode
202.21 Nodular lymphoma Neoplasms 1.03 0.957 – 1.12 0.403 693 6923 all phecode
202.22 Reticulosarcoma Neoplasms 1.09 0.926 – 1.29 0.316 170 1693 all phecode
202.24 Large cell lymphoma Neoplasms 1.09 0.919 – 1.3 0.347 160 1586 all phecode
204 Leukemia Neoplasms 1 0.928 – 1.09 0.905 689 6876 all phecode
204.1 Lymphoid leukemia Neoplasms 1.06 0.924 – 1.23 0.402 236 2354 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.22 0.945 – 1.6 0.134 74 734 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.07 0.915 – 1.27 0.395 173 1724 all phecode
204.2 Myeloid leukemia Neoplasms 0.938 0.835 – 1.06 0.3 265 2633 all phecode
204.21 Myeloid leukemia, acute Neoplasms 0.873 0.75 – 1.03 0.0855 153 1516 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.962 0.743 – 1.28 0.779 61 610 all phecode
204.4 Multiple myeloma Neoplasms 1.06 0.916 – 1.23 0.444 217 2162 all phecode
208 Benign neoplasm of colon Neoplasms 1.01 0.992 – 1.04 0.216 10303 34953 all phecode
209 Neuroendocrine tumors Neoplasms 1.01 0.894 – 1.14 0.919 258 2580 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.999 0.953 – 1.05 0.958 1891 18839 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.01 0.982 – 1.03 0.561 7329 36606 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.02 0.976 – 1.07 0.347 1843 18412 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1 0.952 – 1.05 0.973 1677 15527 all phecode
214 Lipoma Neoplasms 1.01 0.954 – 1.06 0.8 1437 14132 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.994 0.927 – 1.07 0.86 883 8710 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.989 0.959 – 1.02 0.49 4528 39509 all phecode
216 Benign neoplasm of skin Neoplasms 1 0.981 – 1.02 0.859 11528 34919 all phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 1.13 0.97 – 1.34 0.125 174 1701 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.987 0.94 – 1.04 0.59 1786 17184 all phecode
217.1 Nevus, non-neoplastic Neoplasms 0.984 0.937 – 1.04 0.536 1679 16116 all phecode
218 Benign neoplasm of uterus Neoplasms 1.02 0.988 – 1.06 0.206 4301 16661 all phecode
218.1 Uterine leiomyoma Neoplasms 1.03 0.984 – 1.09 0.195 1835 15733 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.01 0.978 – 1.05 0.447 3403 16447 all phecode
220 Benign neoplasm of ovary Neoplasms 1.06 0.986 – 1.14 0.122 893 8783 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.06 1.01 – 1.12 0.0114 2042 14248 all phecode
222 Benign neoplasm of male genital organs Neoplasms 1.01 0.946 – 1.07 0.827 1133 10663 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.02 0.972 – 1.07 0.416 1801 12657 all phecode
224 Benign neoplasm of eye Neoplasms 1.08 0.992 – 1.17 0.0805 691 6752 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.06 0.973 – 1.16 0.186 595 5773 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.962 0.909 – 1.02 0.191 1209 12074 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.972 0.91 – 1.04 0.396 947 9454 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.973 0.869 – 1.1 0.645 289 2890 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.993 0.939 – 1.05 0.814 1329 13264 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.01 0.962 – 1.06 0.671 1690 16896 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.05 0.957 – 1.16 0.295 467 4644 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.01 0.942 – 1.09 0.753 795 7941 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.944 0.86 – 1.04 0.24 435 4350 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.997 0.954 – 1.04 0.886 2149 20946 all phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 1.03 0.969 – 1.09 0.387 1356 13336 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 1 0.978 – 1.03 0.842 7767 36615 all phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 1.01 0.979 – 1.04 0.615 5743 34218 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.03 0.965 – 1.1 0.372 1031 9761 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.978 0.942 – 1.02 0.266 2910 22227 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.981 0.94 – 1.03 0.397 2265 19902 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.962 0.91 – 1.02 0.179 1304 12479 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.992 0.939 – 1.05 0.765 1400 13425 all phecode
242.1 Graves' disease Endocrine/metabolic 1.02 0.93 – 1.12 0.705 515 5068 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.14 0.933 – 1.42 0.201 124 1224 all phecode
242.3 Exophthalmos Endocrine/metabolic 0.981 0.874 – 1.11 0.755 292 2898 all phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.959 0.813 – 1.14 0.625 144 1432 all phecode
244 Hypothyroidism Endocrine/metabolic 0.988 0.963 – 1.01 0.33 8099 32717 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.01 0.96 – 1.06 0.752 1762 17230 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.97 0.917 – 1.03 0.293 1261 11982 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.985 0.96 – 1.01 0.253 7542 32208 all phecode
245 Thyroiditis Endocrine/metabolic 0.97 0.906 – 1.04 0.397 832 7882 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.965 0.895 – 1.04 0.358 686 6517 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.967 0.897 – 1.05 0.395 679 6449 all phecode
246 Other disorders of thyroid Endocrine/metabolic 0.994 0.966 – 1.02 0.666 6129 30240 all phecode
246.2 Thyroid cyst Endocrine/metabolic 1.01 0.826 – 1.26 0.929 101 960 all phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 0.994 0.929 – 1.07 0.858 886 8696 all phecode
249 Secondary diabetes mellitus Endocrine/metabolic 0.961 0.897 – 1.03 0.254 1150 8340 all phecode
250 Diabetes mellitus Endocrine/metabolic 0.997 0.976 – 1.02 0.769 13947 31815 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.957 0.903 – 1.01 0.133 2364 11758 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.962 0.81 – 1.15 0.665 262 960 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.05 0.934 – 1.18 0.432 551 2686 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.955 0.86 – 1.06 0.398 784 3018 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 0.936 0.839 – 1.05 0.245 638 2675 all phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 0.863 0.709 – 1.06 0.151 155 850 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.992 0.967 – 1.02 0.521 9843 29688 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.1 0.93 – 1.3 0.277 282 1327 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.981 0.93 – 1.04 0.496 1941 13510 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.982 0.921 – 1.05 0.578 1643 9668 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 0.983 0.936 – 1.03 0.485 2557 16502 all phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 0.965 0.891 – 1.05 0.387 860 6143 all phecode
250.3 Insulin pump user Endocrine/metabolic 0.979 0.938 – 1.02 0.325 3496 20809 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1 0.977 – 1.03 0.8 8385 30645 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.984 0.936 – 1.04 0.534 1870 15861 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1 0.977 – 1.03 0.732 7553 30071 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.06 0.876 – 1.3 0.555 136 1067 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.961 0.91 – 1.01 0.146 2132 13390 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.993 0.939 – 1.05 0.803 1691 10517 all phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 0.963 0.903 – 1.03 0.247 991 8469 all phecode
251.1 Hypoglycemia Endocrine/metabolic 0.982 0.919 – 1.05 0.609 1207 8570 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.02 0.981 – 1.07 0.282 2282 22119 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.02 0.979 – 1.07 0.304 2088 20335 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.999 0.913 – 1.1 0.986 508 5073 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.03 0.959 – 1.11 0.438 859 8544 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.939 0.833 – 1.07 0.318 263 2621 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.814 0.671 – 1 0.0431 83 826 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.992 0.863 – 1.15 0.916 226 2250 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.954 0.781 – 1.19 0.656 86 860 all phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 1.04 0.866 – 1.27 0.668 121 1209 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.11 0.914 – 1.38 0.302 108 1080 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.994 0.944 – 1.05 0.836 1506 14869 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.04 0.938 – 1.15 0.478 373 3730 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.01 0.875 – 1.17 0.935 183 1830 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.13 0.94 – 1.38 0.202 135 1350 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.979 0.905 – 1.06 0.597 626 6239 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.965 0.892 – 1.05 0.393 596 5941 all phecode
256 Ovarian dysfunction Endocrine/metabolic 1.02 0.957 – 1.08 0.607 1146 10513 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.02 0.947 – 1.1 0.613 742 7128 all phecode
257 Testicular dysfunction Endocrine/metabolic 0.956 0.896 – 1.02 0.174 1015 9238 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.959 0.898 – 1.02 0.208 983 8933 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.961 0.789 – 1.19 0.7 91 910 all phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.953 0.8 – 1.15 0.599 109 1090 all phecode
259 Other endocrine disorders Endocrine/metabolic 1.02 0.958 – 1.09 0.517 1038 10259 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.985 0.948 – 1.02 0.426 2880 26812 all phecode
260.1 Cachexia Endocrine/metabolic 0.937 0.834 – 1.06 0.277 292 2911 all phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 0.948 0.904 – 0.996 0.031 1691 16847 all phecode
260.22 Nutritional marasmus Endocrine/metabolic 0.956 0.883 – 1.04 0.269 614 6140 all phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.02 0.936 – 1.11 0.684 629 6236 all phecode
260.6 Anorexia Endocrine/metabolic 0.967 0.905 – 1.04 0.329 868 8591 all phecode
260.7 Polyphagia Endocrine/metabolic 1.04 0.826 – 1.35 0.76 65 643 all phecode
261 Vitamin deficiency Endocrine/metabolic 1 0.978 – 1.03 0.811 7718 35203 all phecode
261.1 Vitamin A deficiency Endocrine/metabolic 1.19 0.915 – 1.58 0.208 69 690 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.997 0.93 – 1.07 0.926 857 8405 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1 0.975 – 1.03 0.934 7255 35225 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.994 0.763 – 1.33 0.965 52 511 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1 0.944 – 1.07 0.91 1182 11676 all phecode
263 Other nutritional deficiency Endocrine/metabolic 0.977 0.93 – 1.03 0.357 1651 15788 all phecode
264 Lack of normal physiological development Endocrine/metabolic 1.1 0.962 – 1.28 0.166 239 2301 all phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.24 1.01 – 1.55 0.0435 122 1220 all phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 1.05 0.844 – 1.33 0.695 81 772 all phecode
269 Proteinuria Endocrine/metabolic 0.979 0.93 – 1.03 0.415 1694 13981 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.962 0.901 – 1.03 0.242 967 9575 all phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.94 0.814 – 1.1 0.411 170 1697 all phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.932 0.795 – 1.11 0.403 134 1334 all phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 1.01 0.823 – 1.26 0.935 96 954 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.966 0.898 – 1.04 0.368 737 7303 all phecode
270.32 Paraproteinemia Endocrine/metabolic 0.981 0.887 – 1.09 0.705 384 3781 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.12 0.88 – 1.48 0.363 71 695 all phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 0.956 0.746 – 1.25 0.731 69 690 all phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 0.969 0.861 – 1.1 0.609 299 2984 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.05 1.01 – 1.09 0.0254 2907 28132 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.05 1 – 1.09 0.029 2827 27425 all phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.15 0.924 – 1.45 0.224 102 1007 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1 0.984 – 1.03 0.685 18881 26670 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1 0.983 – 1.02 0.72 18843 26654 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.01 0.975 – 1.04 0.729 5928 21600 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.01 0.952 – 1.07 0.774 1360 11837 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.01 0.968 – 1.05 0.75 3538 18449 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.944 0.845 – 1.06 0.311 313 3011 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.04 1 – 1.09 0.0493 2524 22729 all phecode
274.1 Gout Endocrine/metabolic 1.05 1.01 – 1.1 0.025 2409 21991 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.02 0.957 – 1.09 0.554 1082 10576 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.981 0.841 – 1.15 0.807 195 1890 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.994 0.85 – 1.17 0.943 183 1772 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.02 0.985 – 1.05 0.304 4357 37091 all phecode
275.1 Disorders of iron metabolism Hematopoietic 1.11 0.956 – 1.29 0.185 218 2180 all phecode
275.11 Hereditary hemochromatosis Hematopoietic 1.02 0.817 – 1.3 0.86 99 990 all phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 0.716 0.582 – 0.889 0.00189 62 614 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.01 0.954 – 1.08 0.654 1154 11504 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.02 0.985 – 1.06 0.249 3369 31544 all phecode
275.51 Hypocalcemia Endocrine/metabolic 1.03 0.961 – 1.1 0.424 898 8969 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.997 0.943 – 1.05 0.916 1366 13634 all phecode
275.6 Hypercalcemia Endocrine/metabolic 1.02 0.967 – 1.08 0.466 1468 14183 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 0.998 0.975 – 1.02 0.853 9238 37046 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1 0.973 – 1.03 0.991 6352 34366 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1 0.921 – 1.1 0.944 550 5434 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.01 0.971 – 1.06 0.57 2514 23219 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1 0.967 – 1.04 0.812 2992 25216 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1 0.959 – 1.05 0.899 2148 20909 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 0.978 0.935 – 1.02 0.326 2086 20332 all phecode
276.41 Acidosis Endocrine/metabolic 0.975 0.93 – 1.02 0.309 1788 17572 all phecode
276.42 Alkalosis Endocrine/metabolic 0.932 0.85 – 1.02 0.138 476 4741 all phecode
276.5 Hypovolemia Endocrine/metabolic 0.999 0.968 – 1.03 0.934 4574 34527 all phecode
276.6 Fluid overload Endocrine/metabolic 0.977 0.926 – 1.03 0.394 1384 13211 all phecode
276.8 Polydipsia Endocrine/metabolic 0.888 0.76 – 1.05 0.147 124 1240 all phecode
277 Other disorders of metabolism Endocrine/metabolic 0.99 0.959 – 1.02 0.553 4112 35070 all phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1.15 1.03 – 1.28 0.0176 403 3991 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.987 0.915 – 1.07 0.734 720 7161 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.991 0.927 – 1.06 0.805 936 9270 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.967 0.899 – 1.04 0.374 773 7668 all phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1 0.939 – 1.08 0.901 916 8359 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.994 0.976 – 1.01 0.515 19419 27331 all phecode
278.1 Obesity Endocrine/metabolic 0.998 0.979 – 1.02 0.875 17129 27321 all phecode
278.11 Morbid obesity Endocrine/metabolic 1 0.976 – 1.03 0.952 8280 27172 all phecode
278.3 Localized adiposity Endocrine/metabolic 1.08 0.96 – 1.21 0.216 324 3228 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1 0.959 – 1.05 0.891 2104 17411 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.01 0.975 – 1.05 0.512 2934 28612 all phecode
279.1 Immunity deficiency Endocrine/metabolic 0.98 0.923 – 1.04 0.503 1161 11571 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.978 0.874 – 1.1 0.701 330 3278 all phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 1.01 0.94 – 1.09 0.74 754 7516 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.02 0.991 – 1.05 0.162 4885 36552 all phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 1.1 1 – 1.2 0.0434 601 5988 all phecode
280 Iron deficiency anemias Hematopoietic 1.02 0.988 – 1.05 0.218 4626 30873 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.02 0.988 – 1.05 0.23 4484 30649 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.985 0.938 – 1.03 0.532 1771 17196 all phecode
281 Other deficiency anemia Hematopoietic 0.99 0.906 – 1.08 0.823 519 5120 all phecode
281.1 Megaloblastic anemia Hematopoietic 0.94 0.83 – 1.07 0.345 253 2497 all phecode
281.11 Pernicious anemia Hematopoietic 0.913 0.762 – 1.11 0.336 114 1108 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.906 0.787 – 1.05 0.178 187 1817 all phecode
281.9 Deficiency anemias Hematopoietic 1.03 0.916 – 1.17 0.629 285 2830 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.07 0.951 – 1.2 0.278 323 3188 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.02 0.894 – 1.18 0.73 216 2113 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.02 0.879 – 1.19 0.826 192 1920 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.1 0.926 – 1.32 0.29 155 1550 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.08 0.834 – 1.44 0.554 64 633 all phecode
284 Aplastic anemia Hematopoietic 0.978 0.906 – 1.06 0.576 697 6943 all phecode
284.1 Pancytopenia Hematopoietic 0.964 0.889 – 1.05 0.377 612 6100 all phecode
285 Other anemias Hematopoietic 0.994 0.973 – 1.02 0.555 11794 33591 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.996 0.96 – 1.03 0.816 3325 27709 all phecode
285.2 Anemia of chronic disease Hematopoietic 0.998 0.953 – 1.04 0.918 2055 19939 all phecode
285.21 Anemia in chronic kidney disease Hematopoietic 0.957 0.896 – 1.02 0.202 932 9106 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.06 0.975 – 1.15 0.189 690 6892 all phecode
286 Coagulation defects Hematopoietic 1.01 0.972 – 1.04 0.753 3844 33384 all phecode
286.1 Congenital coagulation defects Hematopoietic 0.998 0.878 – 1.14 0.977 250 2466 all phecode
286.11 Von willebrand's disease Hematopoietic 1.18 0.93 – 1.53 0.182 83 822 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.984 0.827 – 1.19 0.858 126 1260 all phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1 0.966 – 1.04 0.926 3354 25918 all phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 1.14 0.913 – 1.45 0.261 97 962 all phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 0.968 0.852 – 1.11 0.629 254 2529 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.999 0.839 – 1.21 0.994 132 1294 all phecode
286.6 Defibrination syndrome Hematopoietic 0.999 0.96 – 1.04 0.979 2579 25377 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.993 0.957 – 1.03 0.709 3014 29294 all phecode
286.8 Hypercoagulable state Hematopoietic 0.999 0.932 – 1.07 0.987 846 8437 all phecode
286.81 Primary hypercoagulable state Hematopoietic 1.01 0.938 – 1.08 0.858 813 8111 all phecode
286.9 Abnormal coagulation profile Hematopoietic 1.02 0.96 – 1.09 0.524 1182 11487 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.998 0.963 – 1.04 0.935 3288 28474 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.01 0.882 – 1.16 0.912 211 2094 all phecode
287.3 Thrombocytopenia Hematopoietic 0.995 0.957 – 1.03 0.78 2938 26323 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.01 0.934 – 1.11 0.736 601 5994 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.06 0.967 – 1.16 0.227 569 5686 all phecode
287.4 Qualitative platelet defects Hematopoietic 0.946 0.795 – 1.14 0.546 112 1120 all phecode
288 Diseases of white blood cells Hematopoietic 1.03 0.995 – 1.06 0.0981 4886 36527 all phecode
288.1 Decreased white blood cell count Hematopoietic 1 0.953 – 1.06 0.924 1599 15951 all phecode
288.11 Neutropenia Hematopoietic 1.01 0.949 – 1.07 0.782 1106 11041 all phecode
288.2 Elevated white blood cell count Hematopoietic 1.03 0.993 – 1.06 0.127 4082 35079 all phecode
288.3 Eosinophilia Hematopoietic 0.9 0.785 – 1.04 0.137 187 1866 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.985 0.938 – 1.03 0.536 1757 17434 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.988 0.924 – 1.06 0.716 918 9087 all phecode
289.4 Lymphadenitis Hematopoietic 1.01 0.973 – 1.04 0.747 3888 34715 all phecode
289.5 Diseases of spleen Hematopoietic 0.951 0.862 – 1.05 0.332 393 3913 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.13 0.992 – 1.3 0.0718 255 2550 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.04 0.934 – 1.16 0.486 385 3813 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.986 0.931 – 1.05 0.638 1318 11547 all phecode
290.1 Dementias Mental Disorders 0.949 0.871 – 1.04 0.244 541 4910 all phecode
290.11 Alzheimer's disease Mental Disorders 1.03 0.869 – 1.24 0.727 151 1389 all phecode
290.12 Dementia with cerebral degenerations Mental Disorders 0.937 0.768 – 1.17 0.538 88 846 all phecode
290.13 Senile dementia Mental Disorders 0.921 0.825 – 1.03 0.146 340 3078 all phecode
290.16 Vascular dementia Mental Disorders 1.02 0.804 – 1.31 0.879 81 777 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.973 0.902 – 1.05 0.474 750 7358 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.971 0.907 – 1.04 0.407 886 8618 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.982 0.943 – 1.02 0.379 2550 24810 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.985 0.847 – 1.16 0.844 175 1750 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.951 0.867 – 1.05 0.287 484 4807 all phecode
291.8 Alteration of consciousness Mental Disorders 0.978 0.934 – 1.02 0.334 2036 19974 all phecode
292 Neurological disorders Mental Disorders 0.986 0.959 – 1.01 0.336 5733 38553 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.988 0.944 – 1.03 0.603 2013 19867 all phecode
292.11 Aphasia Mental Disorders 0.963 0.892 – 1.04 0.341 664 6581 all phecode
292.12 Symbolic dysfunction Mental Disorders 1.06 0.911 – 1.24 0.476 200 1988 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.915 0.826 – 1.02 0.0917 389 3731 all phecode
292.3 Memory loss Mental Disorders 0.996 0.951 – 1.05 0.878 1922 18158 all phecode
292.4 Altered mental status Mental Disorders 0.982 0.942 – 1.02 0.404 2454 22725 all phecode
292.5 Transient alteration of awareness Mental Disorders 0.985 0.895 – 1.09 0.761 430 4285 all phecode
292.6 Hallucinations Mental Disorders 1.14 0.979 – 1.33 0.0985 217 2147 all phecode
293 Symptoms involving head and neck Mental Disorders 0.964 0.872 – 1.07 0.477 414 4127 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.973 0.944 – 1 0.0847 4417 38609 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.986 0.922 – 1.06 0.697 885 8229 all phecode
295.1 Schizophrenia Mental Disorders 0.93 0.799 – 1.1 0.365 138 1339 all phecode
295.2 Paranoid disorders Mental Disorders 1.04 0.863 – 1.27 0.675 118 1079 all phecode
295.3 Psychosis Mental Disorders 0.983 0.912 – 1.06 0.663 716 6694 all phecode
296 Mood disorders Mental Disorders 1.01 0.989 – 1.03 0.359 15356 20858 all phecode
296.1 Bipolar Mental Disorders 0.974 0.921 – 1.03 0.35 1301 11264 all phecode
296.2 Depression Mental Disorders 1.01 0.991 – 1.03 0.269 14833 20856 all phecode
296.22 Major depressive disorder Mental Disorders 1.01 0.99 – 1.03 0.287 13850 20853 all phecode
297 Suicidal ideation or attempt Mental Disorders 1.01 0.948 – 1.09 0.692 985 9050 all phecode
297.1 Suicidal ideation Mental Disorders 1.02 0.945 – 1.1 0.628 788 7310 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.923 0.82 – 1.05 0.196 285 2654 all phecode
300 Anxiety disorders Mental Disorders 1 0.981 – 1.02 0.856 15419 20850 all phecode
300.1 Anxiety disorder Mental Disorders 1.01 0.984 – 1.03 0.608 14517 20855 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1 0.972 – 1.03 0.877 5546 20512 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.02 0.962 – 1.08 0.515 1360 11377 all phecode
300.13 Phobia Mental Disorders 0.955 0.897 – 1.02 0.15 1051 9542 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.03 0.927 – 1.16 0.565 328 3018 all phecode
300.4 Dysthymic disorder Mental Disorders 0.974 0.934 – 1.02 0.232 2420 16552 all phecode
300.8 Acute reaction to stress Mental Disorders 0.951 0.872 – 1.04 0.263 504 4825 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.991 0.924 – 1.06 0.794 843 7909 all phecode
301 Personality disorders Mental Disorders 1.02 0.93 – 1.12 0.673 477 4539 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.06 0.93 – 1.22 0.397 254 2393 all phecode
302 Sexual and gender identity disorders Mental Disorders 1.02 0.982 – 1.06 0.301 3700 13808 all phecode
302.1 Decreased libido Mental Disorders 1.13 1.02 – 1.26 0.0215 447 4331 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.98 0.953 – 1.01 0.166 6808 20043 all phecode
303.1 Dissociative disorder Mental Disorders 1.12 0.943 – 1.34 0.21 161 1573 all phecode
303.3 Psychogenic disorder Mental Disorders 0.979 0.952 – 1.01 0.145 6487 19888 all phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.932 0.852 – 1.02 0.135 471 4623 all phecode
303.4 Somatoform disorder Mental Disorders 0.969 0.914 – 1.03 0.299 1177 11180 all phecode
304 Adjustment reaction Mental Disorders 1.04 1 – 1.08 0.0283 3888 20475 all phecode
305.2 Eating disorder Mental Disorders 1.02 0.957 – 1.1 0.497 901 8329 all phecode
306 Other mental disorder Mental Disorders 0.955 0.911 – 1 0.0623 1815 14133 all phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.11 1.01 – 1.23 0.0273 587 3527 all phecode
306.9 Tension headache Mental Disorders 0.924 0.862 – 0.992 0.0272 753 7277 all phecode
312 Conduct disorders Mental Disorders 0.96 0.85 – 1.09 0.524 254 2501 all phecode
312.3 Impulse control disorder Mental Disorders 1.03 0.82 – 1.32 0.807 74 736 all phecode
313 Pervasive developmental disorders Mental Disorders 1.01 0.964 – 1.07 0.581 1571 14633 all phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1 0.951 – 1.06 0.881 1392 13190 all phecode
313.2 Tics and stuttering Mental Disorders 1.06 0.851 – 1.35 0.632 77 770 all phecode
313.3 Autism Mental Disorders 0.901 0.736 – 1.14 0.339 64 621 all phecode
315 Develomental delays and disorders Mental Disorders 0.987 0.915 – 1.07 0.736 684 6788 all phecode
315.1 Learning disorder Mental Disorders 1.01 0.823 – 1.28 0.906 87 860 all phecode
315.2 Speech and language disorder Mental Disorders 1.12 0.983 – 1.28 0.0965 254 2539 all phecode
316 Substance addiction and disorders Mental Disorders 1.04 1 – 1.08 0.0313 3682 32680 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.07 0.985 – 1.17 0.109 634 6331 all phecode
317 Alcohol-related disorders Mental Disorders 0.991 0.951 – 1.03 0.65 2525 22920 all phecode
317.1 Alcoholism Mental Disorders 1.01 0.961 – 1.06 0.788 1986 19339 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.02 0.919 – 1.13 0.746 408 4080 all phecode
318 Tobacco use disorder Mental Disorders 0.998 0.975 – 1.02 0.875 8622 34842 all phecode
320 Meningitis Neurological 0.972 0.881 – 1.08 0.58 382 3820 all phecode
323 Encephalitis Neurological 1.04 0.89 – 1.23 0.608 181 1809 all phecode
323.8 Encephalitis, non-infectious Neurological 1.07 0.9 – 1.29 0.46 153 1527 all phecode
324 Other CNS infection and poliomyelitis Neurological 0.945 0.839 – 1.07 0.355 288 2880 all phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 0.958 0.755 – 1.25 0.735 53 530 all phecode
327 Sleep disorders Neurological 0.983 0.963 – 1 0.0803 14941 31602 all phecode
327.1 Hypersomnia Neurological 0.984 0.94 – 1.03 0.476 2061 19110 all phecode
327.3 Sleep apnea Neurological 0.983 0.961 – 1 0.123 10909 31304 all phecode
327.31 Central/nonobstroctive sleep apnea Neurological 0.923 0.845 – 1.01 0.0797 492 4784 all phecode
327.32 Obstructive sleep apnea Neurological 0.99 0.967 – 1.01 0.434 8744 30530 all phecode
327.4 Insomnia Neurological 0.986 0.958 – 1.01 0.331 5524 30960 all phecode
327.41 Organic or persistent insomnia Neurological 0.967 0.914 – 1.02 0.238 1265 12120 all phecode
327.5 Parasomnia Neurological 1.03 0.945 – 1.12 0.51 604 5913 all phecode
327.6 Circadian rhythm sleep disorder Neurological 0.967 0.864 – 1.09 0.576 274 2666 all phecode
327.7 Sleep related movement disorders Neurological 0.971 0.926 – 1.02 0.226 1786 17323 all phecode
327.71 Restless legs syndrome Neurological 0.966 0.918 – 1.02 0.179 1570 15360 all phecode
327.72 Sleep related leg cramps Neurological 0.998 0.808 – 1.26 0.989 83 822 all phecode
331 Other cerebral degenerations Neurological 0.957 0.889 – 1.03 0.257 717 7024 all phecode
331.1 Hydrocephalus Neurological 0.963 0.856 – 1.09 0.542 284 2836 all phecode
331.9 Cerebral degeneration, unspecified Neurological 0.981 0.888 – 1.09 0.702 419 4026 all phecode
332 Parkinson's disease Neurological 1.07 0.961 – 1.2 0.221 415 4128 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.02 0.977 – 1.06 0.44 2868 26583 all phecode
333.1 Essential tremor Neurological 0.995 0.921 – 1.08 0.896 725 7163 all phecode
333.2 Myoclonus Neurological 1.08 0.921 – 1.29 0.347 159 1590 all phecode
333.4 Torsion dystonia Neurological 1.07 0.959 – 1.21 0.223 352 3504 all phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 0.928 0.759 – 1.15 0.473 89 890 all phecode
334 Degenerative disease of the spinal cord Neurological 0.962 0.905 – 1.02 0.215 1058 10562 all phecode
334.1 Spinocerebellar disease Neurological 1.14 0.879 – 1.52 0.329 79 790 all phecode
334.2 Anterior horn cell disease Neurological 1.06 0.875 – 1.31 0.551 110 1080 all phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 1.08 0.844 – 1.42 0.559 71 693 all phecode
335 Multiple sclerosis Neurological 0.95 0.862 – 1.05 0.309 396 3951 all phecode
337 Disorders of the autonomic nervous system Neurological 0.994 0.926 – 1.07 0.874 808 7413 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.03 0.922 – 1.15 0.618 370 3164 all phecode
338 Pain Neurological 0.994 0.976 – 1.01 0.538 20346 26417 all phecode
338.1 Acute pain Neurological 0.994 0.974 – 1.01 0.535 15582 26313 all phecode
338.2 Chronic pain Neurological 1 0.982 – 1.03 0.727 10994 26368 all phecode
339 Other headache syndromes Neurological 1 0.98 – 1.03 0.8 9242 34658 all phecode
340 Migraine Neurological 1 0.974 – 1.03 0.985 6708 30587 all phecode
340.1 Migrain with aura Neurological 1.02 0.981 – 1.05 0.371 3624 23684 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.888 0.751 – 1.06 0.172 133 1330 all phecode
342 Hemiplegia Neurological 1.04 0.946 – 1.15 0.399 464 4607 all phecode
343 Infantile cerebral palsy Neurological 0.944 0.768 – 1.19 0.598 85 847 all phecode
344 Other paralytic syndromes Neurological 1 0.927 – 1.08 0.98 682 6808 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.973 0.935 – 1.01 0.174 2553 25307 all phecode
345.1 Epilepsy Neurological 0.932 0.871 – 1 0.0477 747 7465 all phecode
345.11 Generalized convulsive epilepsy Neurological 0.977 0.867 – 1.11 0.716 233 2330 all phecode
345.12 Partial epilepsy Neurological 0.976 0.899 – 1.06 0.566 534 5335 all phecode
345.3 Convulsions Neurological 0.97 0.931 – 1.01 0.141 2396 23796 all phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 1.05 0.906 – 1.23 0.517 183 1824 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.982 0.932 – 1.04 0.518 1472 14587 all phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 1.06 0.889 – 1.28 0.54 120 1181 all phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 0.984 0.819 – 1.2 0.872 110 1100 all phecode
347 Cataplexy and narcolepsy Neurological 1.19 0.952 – 1.5 0.13 101 1010 all phecode
348 Other conditions of brain Neurological 0.99 0.943 – 1.04 0.669 1793 17894 all phecode
348.2 Cerebral edema and compression of brain Neurological 0.972 0.91 – 1.04 0.41 905 9034 all phecode
348.4 Cerebral cysts Neurological 0.857 0.759 – 0.974 0.0147 229 2290 all phecode
348.7 Coma Neurological 0.936 0.829 – 1.07 0.303 229 2275 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.01 0.939 – 1.08 0.861 853 8479 all phecode
348.9 Other conditions of brain, NOS Neurological 1.01 0.966 – 1.05 0.702 2341 23287 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.07 1 – 1.15 0.0506 941 9385 all phecode
350 Abnormal movement Neurological 0.986 0.961 – 1.01 0.291 6706 38762 all phecode
350.1 Abnormal involuntary movements Neurological 1 0.968 – 1.04 0.866 3273 30524 all phecode
350.2 Abnormality of gait Neurological 0.971 0.939 – 1 0.0755 3920 30520 all phecode
350.3 Lack of coordination Neurological 0.997 0.938 – 1.06 0.931 1062 10554 all phecode
350.5 Abnormal reflex Neurological 0.959 0.836 – 1.11 0.565 200 1988 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.01 0.923 – 1.1 0.883 558 5576 all phecode
351 Other peripheral nerve disorders Neurological 1 0.978 – 1.03 0.794 7401 34460 all phecode
352 Disorders of other cranial nerves Neurological 1 0.953 – 1.05 0.96 1714 17106 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.05 0.957 – 1.15 0.336 535 5344 all phecode
352.2 Facial nerve disorders [CN7] Neurological 0.992 0.922 – 1.07 0.837 783 7826 all phecode
353 Nerve root and plexus disorders Neurological 1.01 0.979 – 1.04 0.496 4256 33369 all phecode
353.1 Nerve plexus lesions Neurological 1.03 0.937 – 1.15 0.512 390 3900 all phecode
353.2 Nerve root lesions Neurological 0.974 0.818 – 1.18 0.778 130 1287 all phecode
355 Complex regional/central pain syndrome Neurological 0.926 0.85 – 1.01 0.084 531 5295 all phecode
355.1 Chronic pain syndrome Neurological 1.08 1.01 – 1.17 0.0351 843 8386 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.03 0.981 – 1.07 0.266 2335 20731 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.01 0.974 – 1.05 0.599 3472 29956 all phecode
358 Myoneural disorders Neurological 1.08 1.01 – 1.15 0.0193 1147 11391 all phecode
358.1 Myasthenia gravis Neurological 0.97 0.805 – 1.19 0.76 109 1082 all phecode
359 Muscular dystrophies and other myopathies Neurological 1 0.943 – 1.07 0.962 1134 11274 all phecode
359.1 Muscular dystrophies Neurological 0.983 0.761 – 1.31 0.898 64 632 all phecode
359.2 Myopathy Neurological 1.01 0.95 – 1.08 0.745 1092 10843 all phecode
360 Disorders of the globe Sense Organs 0.998 0.835 – 1.21 0.984 131 1276 all phecode
360.2 Progressive myopia Sense Organs 1.02 0.801 – 1.33 0.891 65 640 all phecode
361 Retinal detachments and defects Sense Organs 0.974 0.906 – 1.05 0.485 733 7131 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.93 0.834 – 1.04 0.203 302 2962 all phecode
362 Other retinal disorders Sense Organs 1.02 0.984 – 1.06 0.282 3569 22997 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.01 0.961 – 1.06 0.777 2172 15483 all phecode
362.21 Macular degeneration, dry Sense Organs 1.01 0.91 – 1.13 0.848 419 3438 all phecode
362.22 Macular degeneration, wet Sense Organs 0.978 0.823 – 1.17 0.808 148 1184 all phecode
362.23 Cystoid macular degeneration of retina Sense Organs 1.04 0.936 – 1.15 0.504 408 3839 all phecode
362.26 Macular puckering of retina Sense Organs 0.955 0.895 – 1.02 0.174 976 8610 all phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.967 0.88 – 1.07 0.491 488 4558 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1 0.956 – 1.06 0.867 1883 13955 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.961 0.9 – 1.03 0.235 976 8527 all phecode
362.31 Separation of retinal layers Sense Organs 1.01 0.917 – 1.12 0.815 413 4056 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.991 0.914 – 1.08 0.834 662 5933 all phecode
362.6 Peripheral retinal degenerations Sense Organs 0.99 0.894 – 1.1 0.856 392 3787 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.04 0.913 – 1.2 0.554 215 2103 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.995 0.875 – 1.14 0.936 241 2368 all phecode
362.9 Retinal edema Sense Organs 1 0.894 – 1.13 0.936 324 2936 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.03 0.938 – 1.13 0.548 492 4746 all phecode
363.3 Chorioretinal scars Sense Organs 0.993 0.888 – 1.12 0.905 332 3184 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.04 0.981 – 1.11 0.176 1132 10772 all phecode
364.1 Corneal opacity Sense Organs 1.05 0.948 – 1.18 0.343 394 3846 all phecode
364.2 Corneal edema Sense Organs 1.18 0.971 – 1.46 0.103 123 1208 all phecode
364.4 Corneal degenerations Sense Organs 0.979 0.887 – 1.08 0.673 402 3962 all phecode
364.41 Keratoconus Sense Organs 1.05 0.827 – 1.37 0.685 75 739 all phecode
364.5 Corneal dystrophy Sense Organs 1.08 0.983 – 1.2 0.111 502 4682 all phecode
364.51 Fuchs' dystrophy Sense Organs 1.02 0.9 – 1.17 0.737 266 2521 all phecode
364.9 Cornea replaced by transplant Sense Organs 1.07 0.869 – 1.33 0.553 91 885 all phecode
365 Glaucoma Sense Organs 1.04 1 – 1.09 0.0435 2672 21326 all phecode
365.1 Open-angle glaucoma Sense Organs 1.06 0.979 – 1.15 0.153 705 6491 all phecode
365.11 Primary open angle glaucoma Sense Organs 1.06 0.952 – 1.18 0.308 403 3681 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.07 0.938 – 1.24 0.316 251 2370 all phecode
366 Cataract Sense Organs 1.01 0.986 – 1.04 0.384 8611 28043 all phecode
366.1 Nonsenile Cataract Sense Organs 0.958 0.839 – 1.1 0.533 207 1979 all phecode
366.2 Senile cataract Sense Organs 1.01 0.981 – 1.04 0.459 5480 24980 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.999 0.976 – 1.02 0.963 8967 37779 all phecode
367.1 Myopia Sense Organs 1.02 0.987 – 1.05 0.277 5014 34677 all phecode
367.2 Astigmatism Sense Organs 1 0.972 – 1.04 0.8 4161 32463 all phecode
367.8 Hypermetropia Sense Organs 0.956 0.914 – 1 0.0491 2039 18599 all phecode
367.9 Blindness and low vision Sense Organs 0.972 0.919 – 1.03 0.333 1277 12356 all phecode
368 Visual disturbances Sense Organs 1 0.976 – 1.03 0.817 5715 39599 all phecode
368.1 Amblyopia Sense Organs 0.995 0.92 – 1.08 0.897 651 6479 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.911 0.86 – 0.967 0.00183 1087 10786 all phecode
368.3 Anisometropia Sense Organs 0.993 0.867 – 1.15 0.927 219 2168 all phecode
368.4 Visual field defects Sense Organs 1.06 0.997 – 1.13 0.0659 1132 11173 all phecode
368.9 Subjective visual disturbances Sense Organs 1.01 0.947 – 1.07 0.815 1070 10620 all phecode
368.91 Psychophysical visual disturbances Sense Organs 0.999 0.822 – 1.23 0.995 120 1171 all phecode
369 Infection of the eye Sense Organs 1.03 0.995 – 1.07 0.0894 3185 28240 all phecode
369.2 Eye infection, viral Sense Organs 0.999 0.911 – 1.1 0.98 502 4954 all phecode
369.5 Conjunctivitis, infectious Sense Organs 1.04 1 – 1.09 0.0438 2716 24970 all phecode
370 Keratitis Sense Organs 1.01 0.956 – 1.07 0.713 1365 13169 all phecode
370.1 Corneal ulcer Sense Organs 0.942 0.824 – 1.08 0.392 223 2194 all phecode
370.2 Superficial keratitis Sense Organs 1.01 0.927 – 1.1 0.815 546 5393 all phecode
370.3 Keratoconjunctivitis Sense Organs 1.05 0.962 – 1.14 0.301 649 6263 all phecode
370.31 Keratoconjunctivitis sicca Sense Organs 1.15 0.971 – 1.37 0.113 179 1677 all phecode
371 Inflammation of the eye Sense Organs 1.01 0.98 – 1.04 0.484 4414 32310 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.02 0.933 – 1.11 0.704 541 5278 all phecode
371.2 Conjunctivitis, noninfectious Sense Organs 1.09 1.02 – 1.17 0.0188 906 8939 all phecode
371.21 Allergic conjunctivitis Sense Organs 1.08 1 – 1.17 0.0475 756 7515 all phecode
371.3 Inflammation of eyelids Sense Organs 0.998 0.963 – 1.03 0.907 3398 26983 all phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 0.885 0.757 – 1.05 0.135 133 1291 all phecode
372 Disorders of conjunctiva Sense Organs 0.975 0.919 – 1.04 0.42 1118 10728 all phecode
374 Other disorders of eyelids Sense Organs 0.994 0.956 – 1.03 0.763 2940 24188 all phecode
374.1 Ectropion or entropion Sense Organs 0.985 0.894 – 1.09 0.767 431 4084 all phecode
374.2 Lagophthalmos Sense Organs 0.991 0.867 – 1.14 0.89 235 2335 all phecode
374.3 Ptosis of eyelid Sense Organs 0.927 0.874 – 0.985 0.0127 1102 10734 all phecode
374.6 Dermatochalasis Sense Organs 1 0.939 – 1.07 0.976 1040 9720 all phecode
375 Disorders of lacrimal system Sense Organs 1.03 0.991 – 1.06 0.144 3694 26045 all phecode
375.1 Dry eyes Sense Organs 1.03 0.993 – 1.06 0.116 4040 26751 all phecode
375.2 Epiphora Sense Organs 0.934 0.85 – 1.03 0.162 442 4354 all phecode
376 Disorders of the orbit Sense Organs 1.02 0.917 – 1.14 0.711 352 3508 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.01 0.945 – 1.08 0.768 913 9021 all phecode
377.1 Optic atrophy Sense Organs 1.04 0.921 – 1.18 0.552 283 2793 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.997 0.918 – 1.09 0.94 585 5775 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.942 0.892 – 0.997 0.0363 1275 12460 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.94 0.88 – 1.01 0.0666 828 8130 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.969 0.831 – 1.14 0.688 170 1686 all phecode
378.5 Paralytic strabismus Sense Organs 0.908 0.817 – 1.01 0.0741 349 3437 all phecode
379 Other disorders of eye Sense Organs 1.01 0.98 – 1.04 0.506 5046 29999 all phecode
379.1 Scleritis and episcleritis Sense Organs 1.01 0.871 – 1.18 0.905 176 1743 all phecode
379.2 Disorders of vitreous body Sense Organs 1 0.966 – 1.04 0.941 3634 23186 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.938 0.796 – 1.12 0.451 135 1258 all phecode
379.4 Anomalies of pupillary function Sense Organs 0.993 0.887 – 1.12 0.909 287 2833 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.15 1.01 – 1.31 0.0373 304 2948 all phecode
379.51 Pigmentary iris degeneration Sense Organs 1.29 1.01 – 1.69 0.0492 77 731 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.03 0.968 – 1.1 0.362 1129 11130 all phecode
380 Disorders of external ear Sense Organs 1 0.958 – 1.05 0.984 2242 20393 all phecode
380.1 Otitis externa Sense Organs 0.986 0.936 – 1.04 0.6 1469 14580 all phecode
380.4 Impacted cerumen Sense Organs 1.01 0.971 – 1.05 0.601 2648 23557 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1 0.97 – 1.03 0.951 4255 36417 all phecode
381.1 Otitis media Sense Organs 1.02 0.984 – 1.06 0.274 3079 29813 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.02 0.978 – 1.06 0.38 2610 25602 all phecode
381.2 Eustachian tube disorders Sense Organs 0.99 0.944 – 1.04 0.695 1816 17827 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.08 0.922 – 1.29 0.342 153 1530 all phecode
381.9 Otorrhea Sense Organs 0.997 0.901 – 1.11 0.951 372 3713 all phecode
382 Otalgia Sense Organs 1.01 0.968 – 1.06 0.553 1884 18673 all phecode
383 Otosclerosis Sense Organs 0.952 0.811 – 1.13 0.56 124 1240 all phecode
384 Other disorders of tympanic membrane Sense Organs 0.978 0.895 – 1.07 0.626 516 5156 all phecode
384.1 Myringitis Sense Organs 0.974 0.752 – 1.31 0.846 51 502 all phecode
384.4 Perforation of tympanic membrane Sense Organs 0.993 0.901 – 1.1 0.896 403 4029 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.1 0.996 – 1.23 0.0636 432 4320 all phecode
385.3 Cholesteatoma Sense Organs 1.05 0.934 – 1.19 0.412 277 2770 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.986 0.834 – 1.18 0.877 118 1180 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.97 0.927 – 1.02 0.204 1882 18186 all phecode
386.1 Meniere's disease Sense Organs 0.929 0.834 – 1.04 0.189 319 3156 all phecode
386.2 Peripheral or central vertigo Sense Organs 0.975 0.927 – 1.03 0.324 1586 15423 all phecode
386.21 Central origin vertigo Sense Organs 0.982 0.927 – 1.04 0.549 1208 11844 all phecode
386.3 Labyrinthitis Sense Organs 0.971 0.922 – 1.02 0.261 1482 14530 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.01 0.983 – 1.04 0.512 6933 38286 all phecode
388 Other disorders of ear Sense Organs 1.02 0.955 – 1.09 0.557 960 9501 all phecode
389 Hearing loss Sense Organs 0.993 0.969 – 1.02 0.562 8182 38069 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.989 0.957 – 1.02 0.526 4107 29258 all phecode
389.2 Conductive hearing loss Sense Organs 1.03 0.961 – 1.1 0.435 905 9042 all phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.888 0.777 – 1.02 0.088 192 1808 all phecode
389.4 Tinnitus Sense Organs 0.971 0.931 – 1.01 0.17 2291 22130 all phecode
389.5 Disorders of acoustic nerve Sense Organs 0.918 0.778 – 1.1 0.325 124 1229 all phecode
394 Rheumatic disease of the heart valves Circulatory System 0.933 0.886 – 0.984 0.00936 1458 13732 all phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 0.909 0.818 – 1.01 0.0817 350 3415 all phecode
394.2 Mitral valve disease Circulatory System 0.918 0.842 – 1 0.0559 462 4560 all phecode
394.3 Aortic valve disease Circulatory System 0.954 0.819 – 1.12 0.551 176 1691 all phecode
394.4 Acute rheumatic heart disease Circulatory System 0.868 0.676 – 1.14 0.282 55 546 all phecode
394.7 Disease of tricuspid valve Circulatory System 0.896 0.827 – 0.974 0.00844 587 5739 all phecode
395 Heart valve disorders Circulatory System 0.978 0.946 – 1.01 0.186 3976 28748 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.96 0.919 – 1 0.0701 2175 20441 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.971 0.928 – 1.02 0.218 2060 17194 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 0.926 0.851 – 1.01 0.0764 493 4864 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.01 0.829 – 1.26 0.899 108 1080 all phecode
395.6 Heart valve replaced Circulatory System 0.981 0.924 – 1.04 0.528 1177 10833 all phecode
396 Abnormal heart sounds Circulatory System 0.983 0.954 – 1.01 0.281 4718 34395 all phecode
401 Hypertension Circulatory System 1 0.984 – 1.03 0.681 23317 23367 all phecode
401.1 Essential hypertension Circulatory System 1 0.983 – 1.03 0.701 23158 23364 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 0.997 0.959 – 1.04 0.897 3503 14616 all phecode
401.21 Hypertensive heart disease Circulatory System 1.06 0.987 – 1.14 0.11 893 6607 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.988 0.946 – 1.03 0.592 2584 13072 all phecode
401.3 Other hypertensive complications Circulatory System 0.972 0.933 – 1.01 0.175 2679 15833 all phecode
411 Ischemic Heart Disease Circulatory System 0.993 0.968 – 1.02 0.585 8807 30299 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.975 0.912 – 1.04 0.471 937 8574 all phecode
411.2 Myocardial infarction Circulatory System 0.989 0.954 – 1.03 0.559 3594 21716 all phecode
411.3 Angina pectoris Circulatory System 0.992 0.951 – 1.04 0.722 2485 18304 all phecode
411.4 Coronary atherosclerosis Circulatory System 0.993 0.967 – 1.02 0.631 7555 27492 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.05 0.884 – 1.25 0.612 156 1529 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.993 0.964 – 1.02 0.64 6331 25741 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.08 0.974 – 1.19 0.155 442 4211 all phecode
414 Other forms of chronic heart disease Circulatory System 0.979 0.943 – 1.02 0.27 3101 22616 all phecode
414.2 ASCVD Circulatory System 1.01 0.931 – 1.09 0.895 718 6816 all phecode
415 Pulmonary heart disease Circulatory System 1 0.967 – 1.04 0.905 3366 30208 all phecode
415.1 Acute pulmonary heart disease Circulatory System 1.01 0.966 – 1.06 0.586 1912 19014 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.01 0.965 – 1.06 0.622 1906 18953 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.99 0.944 – 1.04 0.686 1808 17605 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1 0.927 – 1.09 0.962 706 7032 all phecode
416 Cardiomegaly Circulatory System 1.05 0.986 – 1.11 0.143 1254 12372 all phecode
418 Nonspecific chest pain Circulatory System 1 0.981 – 1.02 0.863 12650 33952 all phecode
418.1 Precordial pain Circulatory System 0.995 0.944 – 1.05 0.842 1471 13782 all phecode
420 Carditis Circulatory System 0.984 0.936 – 1.04 0.543 1588 15680 all phecode
420.1 Myocarditis Circulatory System 1.06 0.839 – 1.35 0.646 97 958 all phecode
420.2 Pericarditis Circulatory System 1.02 0.951 – 1.1 0.58 842 8402 all phecode
420.21 Acute pericarditis Circulatory System 1.05 0.902 – 1.23 0.556 177 1764 all phecode
420.22 Chronic pericarditis Circulatory System 1.23 0.999 – 1.54 0.0554 117 1153 all phecode
420.3 Endocarditis Circulatory System 0.926 0.864 – 0.995 0.0337 764 7535 all phecode
425 Cardiomyopathy Circulatory System 1.04 0.989 – 1.09 0.142 2078 19881 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.03 0.985 – 1.08 0.188 1989 19025 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.991 0.864 – 1.15 0.905 208 2050 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.28 1.09 – 1.51 0.00342 201 1992 all phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.03 0.92 – 1.17 0.577 317 3170 all phecode
425.8 Other cardiomyopathy Circulatory System 0.974 0.794 – 1.21 0.802 95 931 all phecode
426 Cardiac conduction disorders Circulatory System 0.994 0.972 – 1.02 0.621 12327 25440 all phecode
426.2 Atrioventricular [AV] block Circulatory System 0.953 0.908 – 1 0.0578 1903 11501 all phecode
426.21 First degree AV block Circulatory System 0.954 0.9 – 1.01 0.12 1313 8899 all phecode
426.22 Mobitz II AV block Circulatory System 0.957 0.76 – 1.25 0.721 64 553 all phecode
426.23 Second degree AV block Circulatory System 0.903 0.796 – 1.03 0.121 216 1925 all phecode
426.24 Atrioventricular block, complete Circulatory System 0.892 0.814 – 0.98 0.0149 461 3823 all phecode
426.25 Other heart block Circulatory System 0.916 0.803 – 1.05 0.201 203 1803 all phecode
426.3 Bundle branch block Circulatory System 1.02 0.973 – 1.07 0.43 2306 13999 all phecode
426.31 Right bundle branch block Circulatory System 1 0.949 – 1.06 0.909 1423 10758 all phecode
426.32 Left bundle branch block Circulatory System 1.04 0.969 – 1.11 0.291 969 8110 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.916 0.761 – 1.12 0.368 82 820 all phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 0.994 0.971 – 1.02 0.632 10577 25186 all phecode
426.8 Other cardiac conduction disorders Circulatory System 0.955 0.883 – 1.03 0.252 679 6650 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.957 0.91 – 1.01 0.0866 1754 11536 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.921 0.868 – 0.979 0.00757 1171 8184 all phecode
426.92 Cardiac defibrillator in situ Circulatory System 0.958 0.894 – 1.03 0.232 846 7320 all phecode
427 Cardiac dysrhythmias Circulatory System 1 0.981 – 1.02 0.923 17397 25735 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 0.976 0.937 – 1.02 0.266 2474 18178 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.957 0.91 – 1.01 0.0944 1595 14293 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.01 0.947 – 1.07 0.85 1181 9915 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1 0.969 – 1.04 0.945 5313 18688 all phecode
427.21 Atrial fibrillation Circulatory System 1.01 0.975 – 1.04 0.642 5188 18409 all phecode
427.22 Atrial flutter Circulatory System 0.992 0.941 – 1.05 0.752 1693 11042 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.989 0.964 – 1.01 0.386 8688 25552 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.968 0.887 – 1.06 0.474 536 5233 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.08 0.937 – 1.27 0.286 216 2118 all phecode
427.42 Cardiac arrest Circulatory System 0.961 0.872 – 1.06 0.439 410 4034 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.987 0.96 – 1.01 0.346 6905 25457 all phecode
427.6 Premature beats Circulatory System 1 0.957 – 1.05 0.997 2359 16248 all phecode
427.61 Supraventricular premature beats Circulatory System 0.964 0.89 – 1.05 0.362 670 6287 all phecode
427.7 Tachycardia NOS Circulatory System 0.999 0.969 – 1.03 0.933 5124 25531 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.96 0.897 – 1.03 0.248 912 7501 all phecode
427.9 Palpitations Circulatory System 0.993 0.962 – 1.03 0.684 4430 24505 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.984 0.951 – 1.02 0.336 4300 23663 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 0.989 0.954 – 1.02 0.534 3756 22446 all phecode
428.2 Heart failure NOS Circulatory System 0.997 0.962 – 1.03 0.879 3701 21722 all phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 0.992 0.944 – 1.04 0.743 1765 14476 all phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.02 0.972 – 1.08 0.367 1648 13395 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 0.996 0.975 – 1.02 0.691 12635 32504 all phecode
429.1 Heart transplant/surgery Circulatory System 0.981 0.925 – 1.04 0.525 1219 11696 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.986 0.959 – 1.01 0.32 6322 29232 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 0.998 0.975 – 1.02 0.874 9650 32421 all phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 0.991 0.92 – 1.07 0.82 723 7072 all phecode
430 Intracranial hemorrhage Circulatory System 0.98 0.911 – 1.06 0.581 789 7842 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.982 0.867 – 1.12 0.773 261 2610 all phecode
430.2 Intracerebral hemorrhage Circulatory System 0.957 0.864 – 1.07 0.417 368 3671 all phecode
430.3 Subdural hemorrhage Circulatory System 0.995 0.882 – 1.13 0.937 272 2680 all phecode
433 Cerebrovascular disease Circulatory System 1.01 0.977 – 1.04 0.684 5463 32242 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.02 0.969 – 1.07 0.514 1978 16212 all phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.04 0.912 – 1.2 0.548 260 2517 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.25 0.953 – 1.66 0.111 80 789 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.974 0.935 – 1.02 0.218 2437 21732 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.975 0.935 – 1.02 0.245 2357 21103 all phecode
433.3 Cerebral ischemia Circulatory System 0.991 0.953 – 1.03 0.673 2780 22868 all phecode
433.31 Transient cerebral ischemia Circulatory System 0.992 0.951 – 1.04 0.724 2409 20762 all phecode
433.5 Cerebral aneurysm Circulatory System 0.994 0.909 – 1.09 0.903 474 4724 all phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 0.949 0.866 – 1.04 0.268 464 4518 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.947 0.88 – 1.02 0.158 695 6822 all phecode
440 Atherosclerosis Circulatory System 0.995 0.954 – 1.04 0.835 2477 19724 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.994 0.873 – 1.14 0.926 231 2291 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.97 0.92 – 1.02 0.263 1516 13532 all phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 0.924 0.822 – 1.04 0.194 274 2669 all phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 0.967 0.908 – 1.03 0.305 1040 9647 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.01 0.935 – 1.08 0.882 846 8124 all phecode
441 Vascular insufficiency of intestine Circulatory System 0.957 0.876 – 1.05 0.332 515 5115 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.98 0.86 – 1.12 0.761 240 2387 all phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 0.97 0.826 – 1.15 0.72 154 1536 all phecode
442 Other aneurysm Circulatory System 0.974 0.936 – 1.01 0.19 2779 21466 all phecode
442.1 Aortic aneurysm Circulatory System 0.966 0.923 – 1.01 0.139 2054 16492 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.991 0.934 – 1.05 0.773 1189 10558 all phecode
442.2 Aneurysm of iliac artery Circulatory System 0.965 0.837 – 1.12 0.627 202 2002 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.979 0.843 – 1.15 0.786 179 1765 all phecode
442.4 Arterial dissection Circulatory System 0.991 0.853 – 1.16 0.904 184 1840 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.05 0.95 – 1.17 0.337 399 3978 all phecode
443 Peripheral vascular disease Circulatory System 0.98 0.944 – 1.02 0.29 3086 24814 all phecode
443.1 Raynaud's syndrome Circulatory System 0.981 0.912 – 1.06 0.616 742 7390 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.839 0.735 – 0.962 0.00986 220 2087 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 0.973 0.934 – 1.01 0.191 2557 21985 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.992 0.95 – 1.04 0.73 2341 18862 all phecode
444 Arterial embolism and thrombosis Circulatory System 0.962 0.896 – 1.03 0.282 848 8423 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.955 0.851 – 1.08 0.444 313 3099 all phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 0.86 0.735 – 1.01 0.0622 155 1548 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 0.96 0.877 – 1.05 0.377 460 4559 all phecode
446.4 Wegener's granulomatosis Circulatory System 0.919 0.771 – 1.11 0.361 109 1075 all phecode
446.5 Giant cell arteritis Circulatory System 0.997 0.804 – 1.26 0.981 79 749 all phecode
446.9 Arteritis NOS Circulatory System 0.932 0.83 – 1.05 0.238 289 2876 all phecode
447 Other disorders of arteries and arterioles Circulatory System 0.976 0.938 – 1.02 0.239 2647 22765 all phecode
447.1 Stricture of artery Circulatory System 0.996 0.911 – 1.09 0.929 523 5163 all phecode
447.7 Aortic ectasia Circulatory System 0.965 0.899 – 1.04 0.32 804 7938 all phecode
448 Disease of capillaries Circulatory System 0.967 0.914 – 1.02 0.252 1237 12127 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.998 0.955 – 1.04 0.939 2104 20985 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.05 0.971 – 1.14 0.231 738 7355 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.14 0.991 – 1.33 0.0725 244 2437 all phecode
452 Other venous embolism and thrombosis Circulatory System 1.02 0.987 – 1.05 0.268 4957 29867 all phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 0.936 0.835 – 1.06 0.263 276 2747 all phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1.02 0.984 – 1.06 0.28 3260 26940 all phecode
452.8 Postphlebitic syndrome Circulatory System 1.25 1.05 – 1.5 0.0159 154 1529 all phecode
453 Chronic venous hypertension Circulatory System 1.05 0.914 – 1.21 0.516 220 2168 all phecode
454 Varicose veins Circulatory System 1.05 1.01 – 1.09 0.0167 2827 24555 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1.05 1.01 – 1.1 0.0236 2469 21426 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.06 1 – 1.12 0.0376 1565 15056 all phecode
455 Hemorrhoids Circulatory System 1 0.973 – 1.03 0.922 5799 29818 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.04 1 – 1.08 0.046 3097 24898 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.969 0.926 – 1.01 0.171 2095 15309 all phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 0.967 0.867 – 1.09 0.562 324 3221 all phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 0.957 0.914 – 1 0.0661 1973 14689 all phecode
458 Hypotension Circulatory System 1.01 0.976 – 1.04 0.702 5091 32185 all phecode
458.1 Orthostatic hypotension Circulatory System 0.958 0.908 – 1.01 0.121 1344 12938 all phecode
458.2 Iatrogenic hypotension Circulatory System 0.98 0.921 – 1.04 0.527 1109 11012 all phecode
458.9 Hypotension NOS Circulatory System 0.999 0.969 – 1.03 0.964 4618 31186 all phecode
459 Other disorders of circulatory system Circulatory System 1.02 0.993 – 1.05 0.149 7825 34792 all phecode
459.1 Hemorrhage NOS Circulatory System 1.07 0.997 – 1.16 0.0622 834 8215 all phecode
459.7 Blood vessel replaced Circulatory System 1 0.947 – 1.06 0.915 1305 13023 all phecode
459.9 Circulatory disease NEC Circulatory System 1.01 0.986 – 1.04 0.354 6706 33592 all phecode
464 Acute sinusitis Respiratory 1 0.974 – 1.04 0.775 4792 32137 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.01 0.988 – 1.03 0.355 9601 35915 all phecode
465.2 Acute pharyngitis Respiratory 1.01 0.985 – 1.04 0.356 5310 32365 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.02 0.924 – 1.13 0.701 443 4428 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.986 0.94 – 1.04 0.567 1797 17640 all phecode
471 Nasal polyps Respiratory 1.02 0.939 – 1.12 0.619 592 5881 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.996 0.949 – 1.05 0.885 1797 16986 all phecode
473 Diseases of the larynx and vocal cords Respiratory 0.968 0.933 – 1.01 0.091 2983 25244 all phecode
473.1 Chronic laryngitis Respiratory 1.03 0.825 – 1.33 0.807 68 674 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.918 0.851 – 0.994 0.0323 628 6254 all phecode
473.4 Voice disturbance Respiratory 0.949 0.911 – 0.99 0.0137 2336 21975 all phecode
474 Acute and chronic tonsillitis Respiratory 1 0.937 – 1.08 0.935 880 7892 all phecode
474.1 Acute tonsillitis Respiratory 1.05 0.944 – 1.18 0.365 335 3181 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.977 0.907 – 1.06 0.552 700 6445 all phecode
475 Chronic sinusitis Respiratory 0.989 0.958 – 1.02 0.488 4378 27891 all phecode
475.9 Postnasal drip Respiratory 0.931 0.874 – 0.994 0.0285 922 9017 all phecode
476 Allergic rhinitis Respiratory 0.983 0.963 – 1 0.119 12687 28117 all phecode
477 Epistaxis or throat hemorrhage Respiratory 0.965 0.91 – 1.02 0.24 1150 11318 all phecode
478 Throat pain Respiratory 0.962 0.876 – 1.06 0.43 426 4195 all phecode
479 Other upper respiratory disease Respiratory 0.982 0.955 – 1.01 0.217 5627 28048 all phecode
480 Pneumonia Respiratory 0.994 0.967 – 1.02 0.661 5947 37034 all phecode
480.1 Bacterial pneumonia Respiratory 1.03 0.971 – 1.1 0.307 1155 11495 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.08 0.987 – 1.18 0.0988 568 5644 all phecode
480.12 Pseudomonal pneumonia Respiratory 0.958 0.824 – 1.13 0.592 153 1523 all phecode
480.13 MRSA pneumonia Respiratory 0.997 0.831 – 1.21 0.977 117 1165 all phecode
480.2 Viral pneumonia Respiratory 0.979 0.851 – 1.14 0.775 202 1992 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.987 0.846 – 1.16 0.873 159 1590 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.937 0.789 – 1.12 0.463 135 1312 all phecode
481 Influenza Respiratory 0.985 0.932 – 1.04 0.599 1355 13284 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.02 0.981 – 1.05 0.38 3412 29871 all phecode
495 Asthma Respiratory 0.985 0.962 – 1.01 0.197 8671 33569 all phecode
495.1 Chronic obstructive asthma Respiratory 0.89 0.813 – 0.978 0.0134 397 3925 all phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 0.805 0.667 – 0.986 0.029 81 802 all phecode
495.2 Asthma with exacerbation Respiratory 0.998 0.949 – 1.05 0.951 1629 16033 all phecode
496 Chronic airway obstruction Respiratory 0.975 0.947 – 1 0.0854 5343 28343 all phecode
496.1 Emphysema Respiratory 1.01 0.962 – 1.05 0.783 2134 19414 all phecode
496.2 Chronic bronchitis Respiratory 0.962 0.931 – 0.994 0.0191 4128 26624 all phecode
496.21 Obstructive chronic bronchitis Respiratory 0.956 0.924 – 0.989 0.00822 3747 25467 all phecode
496.3 Bronchiectasis Respiratory 0.97 0.892 – 1.06 0.477 549 5453 all phecode
497 Bronchitis Respiratory 1 0.957 – 1.05 0.915 1946 18824 all phecode
498 Acute bronchospasm Respiratory 0.969 0.886 – 1.06 0.501 496 4943 all phecode
499 Cystic fibrosis Respiratory 0.786 0.68 – 0.914 0.00128 151 1510 all phecode
500 Lung disease due to external agents Respiratory 1.01 0.922 – 1.1 0.903 557 5551 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.987 0.817 – 1.22 0.893 92 920 all phecode
500.2 Pneumoconiosis Respiratory 0.95 0.771 – 1.2 0.643 78 764 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.07 0.982 – 1.17 0.128 634 6225 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.01 0.938 – 1.09 0.829 815 8076 all phecode
503 Pulmonary congestion and hypostasis Respiratory 0.947 0.884 – 1.02 0.128 835 8243 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.987 0.908 – 1.07 0.752 595 5878 all phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 0.954 0.855 – 1.07 0.411 311 3084 all phecode
505 Other pulmonary inflamation or edema Respiratory 0.985 0.936 – 1.04 0.556 1638 15749 all phecode
506 Empyema and pneumothorax Respiratory 0.988 0.951 – 1.03 0.558 2894 25235 all phecode
507 Pleurisy; pleural effusion Respiratory 1 0.962 – 1.04 0.998 2916 26208 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.99 0.949 – 1.03 0.647 2382 22588 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 0.976 0.944 – 1.01 0.145 4032 29477 all phecode
509.1 Respiratory failure Respiratory 0.979 0.934 – 1.03 0.377 1937 18949 all phecode
509.2 Respiratory insufficiency Respiratory 0.993 0.935 – 1.06 0.814 1174 11679 all phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 0.985 0.937 – 1.04 0.56 1689 16489 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.951 0.907 – 0.999 0.0428 1741 17249 all phecode
510 Other diseases of lung Respiratory 0.989 0.961 – 1.02 0.46 5503 35907 all phecode
510.2 Lung transplant Respiratory 1.05 0.907 – 1.24 0.512 176 1757 all phecode
512 Other symptoms of respiratory system Respiratory 1.01 0.996 – 1.03 0.126 18621 28154 all phecode
512.1 Wheezing Respiratory 0.987 0.936 – 1.04 0.649 1409 13516 all phecode
512.2 Painful respiration Respiratory 0.998 0.957 – 1.04 0.932 2309 21263 all phecode
512.3 Abnormal chest sounds Respiratory 1.02 0.902 – 1.15 0.79 291 2845 all phecode
512.7 Shortness of breath Respiratory 1.01 0.985 – 1.03 0.512 10034 28081 all phecode
512.8 Cough Respiratory 1.01 0.983 – 1.03 0.569 9501 28148 all phecode
512.9 Other dyspnea Respiratory 1.01 0.988 – 1.03 0.384 10804 28104 all phecode
513 Respiratory abnormalities Respiratory 1 0.98 – 1.02 0.984 12932 33822 all phecode
513.3 Hypoventilation Respiratory 0.979 0.915 – 1.05 0.556 880 8646 all phecode
513.31 Apnea Respiratory 0.976 0.889 – 1.08 0.623 462 4607 all phecode
513.32 Orthopnea Respiratory 0.969 0.851 – 1.11 0.641 220 2160 all phecode
513.4 Hyperventilation Respiratory 0.942 0.864 – 1.03 0.186 515 5124 all phecode
513.8 Disorders of diaphragm Respiratory 0.913 0.812 – 1.03 0.132 258 2557 all phecode
514 Abnormal findings examination of lungs Respiratory 0.972 0.945 – 1 0.0563 5365 34834 all phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 0.939 0.83 – 1.07 0.33 258 2580 all phecode
514.2 Solitary pulmonary nodule Respiratory 0.997 0.96 – 1.04 0.863 3018 27338 all phecode
516 Abnormal sputum Respiratory 0.98 0.909 – 1.06 0.595 735 7332 all phecode
516.1 Hemoptysis Respiratory 0.951 0.879 – 1.03 0.224 611 6080 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.983 0.957 – 1.01 0.203 6458 39057 all phecode
519.1 Tracheostomy complications Respiratory 0.975 0.853 – 1.12 0.718 214 2136 all phecode
519.2 Respiratory complications Respiratory 1.01 0.921 – 1.12 0.772 445 4430 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.977 0.928 – 1.03 0.371 1588 15787 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.985 0.956 – 1.02 0.347 4706 34489 all phecode
520 Disorders of tooth development Digestive 0.967 0.874 – 1.08 0.522 369 3690 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.909 0.782 – 1.07 0.227 165 1642 all phecode
520.2 Disturbances in tooth eruption Digestive 0.94 0.827 – 1.08 0.353 218 2172 all phecode
521 Diseases of hard tissues of teeth Digestive 1.01 0.947 – 1.09 0.689 898 8954 all phecode
521.1 Dental caries Digestive 0.998 0.93 – 1.07 0.964 837 8349 all phecode
521.2 Dental abrasion, erosion and attrition Digestive 1.14 0.885 – 1.54 0.324 52 510 all phecode
522 Diseases of pulp and periapical tissues Digestive 0.983 0.901 – 1.08 0.7 535 5340 all phecode
522.5 Periapical abscess Digestive 1 0.91 – 1.1 0.991 459 4583 all phecode
523 Gingival and periodontal diseases Digestive 1 0.929 – 1.08 0.968 718 7180 all phecode
523.1 Gingivitis Digestive 0.919 0.782 – 1.09 0.317 142 1418 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.04 0.935 – 1.17 0.464 364 3636 all phecode
523.31 Acute periodontitis Digestive 1.03 0.922 – 1.17 0.574 311 3109 all phecode
523.32 Chronic periodontitis Digestive 1.03 0.849 – 1.27 0.748 122 1204 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.95 0.861 – 1.05 0.319 363 3630 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.967 0.853 – 1.11 0.61 220 2200 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1 0.943 – 1.07 0.914 1039 10382 all phecode
525.1 Loss of teeth or edentulism Digestive 0.944 0.853 – 1.05 0.274 374 3731 all phecode
526 Diseases of the jaws Digestive 1.02 0.978 – 1.06 0.393 2680 26455 all phecode
526.1 Cysts of the jaws Digestive 0.977 0.863 – 1.11 0.721 247 2470 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.984 0.87 – 1.12 0.806 241 2383 all phecode
526.4 Temporomandibular joint disorders Digestive 1.04 0.984 – 1.1 0.17 1504 15025 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.04 0.978 – 1.1 0.221 1187 11858 all phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 1.02 0.95 – 1.11 0.541 741 7400 all phecode
526.5 Inflammatory conditions of jaw Digestive 0.956 0.851 – 1.08 0.455 287 2864 all phecode
526.8 Exostosis of jaw Digestive 1.19 0.882 – 1.65 0.266 53 521 all phecode
526.9 Jaw disease NOS Digestive 0.978 0.895 – 1.07 0.636 487 4867 all phecode
527 Diseases of the salivary glands Digestive 1.01 0.965 – 1.06 0.602 1781 17771 all phecode
527.1 Hypertrophy of salivary gland Digestive 0.938 0.727 – 1.24 0.629 58 579 all phecode
527.2 Sialoadenitis Digestive 1.06 0.954 – 1.18 0.3 394 3936 all phecode
527.7 Disturbance of salivary secretion Digestive 1.03 0.964 – 1.11 0.367 952 9481 all phecode
527.8 Other specified diseases of the salivary glands Digestive 0.966 0.855 – 1.1 0.583 254 2540 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.989 0.951 – 1.03 0.592 2643 26197 all phecode
528.1 Stomatitis and mucositis Digestive 1 0.926 – 1.09 0.977 668 6657 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.02 0.887 – 1.17 0.828 211 2110 all phecode
528.12 Oral aphthae Digestive 0.989 0.86 – 1.15 0.876 215 2137 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.851 0.757 – 0.962 0.00783 235 2338 all phecode
528.4 Cysts of oral soft tissues Digestive 1.19 0.979 – 1.47 0.0858 124 1229 all phecode
528.41 Cyst of the salivary gland Digestive 1.08 0.844 – 1.41 0.557 77 760 all phecode
528.5 Diseases of lips Digestive 0.961 0.876 – 1.06 0.397 462 4602 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1.23 1.01 – 1.5 0.0384 137 1370 all phecode
528.7 Sialolithiasis Digestive 0.902 0.775 – 1.06 0.188 163 1623 all phecode
529 Diseases and other conditions of the tongue Digestive 1 0.927 – 1.09 0.959 690 6878 all phecode
529.1 Glossitis Digestive 1.12 0.936 – 1.37 0.222 129 1281 all phecode
529.6 Glossodynia Digestive 1.15 0.971 – 1.37 0.115 168 1652 all phecode
530 Diseases of esophagus Digestive 0.995 0.976 – 1.01 0.628 17081 27931 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.997 0.977 – 1.02 0.744 16572 27931 all phecode
530.11 GERD Digestive 0.995 0.976 – 1.02 0.626 16143 27929 all phecode
530.12 Ulcer of esophagus Digestive 0.95 0.86 – 1.05 0.322 400 3983 all phecode
530.13 Barrett's esophagus Digestive 0.998 0.927 – 1.08 0.95 762 7584 all phecode
530.14 Reflux esophagitis Digestive 1.01 0.968 – 1.07 0.546 1900 17495 all phecode
530.15 Eosinophilic esophagitis Digestive 1.12 0.969 – 1.3 0.136 221 2210 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.973 0.899 – 1.06 0.511 651 6473 all phecode
530.3 Stricture and stenosis of esophagus Digestive 0.98 0.917 – 1.05 0.568 911 8971 all phecode
530.5 Disorders of esophageal motility Digestive 0.962 0.884 – 1.05 0.372 548 5432 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.871 0.747 – 1.03 0.0887 129 1265 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.07 0.862 – 1.36 0.56 82 812 all phecode
530.9 Heartburn Digestive 1.01 0.959 – 1.07 0.667 1519 14928 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.99 0.947 – 1.04 0.668 2073 20617 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.947 0.859 – 1.05 0.285 391 3883 all phecode
531.2 Gastric ulcer Digestive 0.99 0.934 – 1.05 0.737 1201 11970 all phecode
531.3 Duodenal ulcer Digestive 0.992 0.905 – 1.09 0.873 467 4640 all phecode
531.4 Peptic ulcer, site unspecified Digestive 0.991 0.925 – 1.06 0.807 804 8018 all phecode
531.5 Gastrojejunal ulcer Digestive 1.01 0.858 – 1.2 0.933 150 1500 all phecode
532 Dysphagia Digestive 0.983 0.955 – 1.01 0.252 5585 26852 all phecode
535 Gastritis and duodenitis Digestive 1.01 0.971 – 1.05 0.631 2799 27335 all phecode
535.1 Acute gastritis Digestive 1.01 0.948 – 1.07 0.846 1178 11750 all phecode
535.2 Atrophic gastritis Digestive 1.02 0.91 – 1.15 0.735 344 3413 all phecode
535.6 Duodenitis Digestive 1.09 0.973 – 1.22 0.147 334 3337 all phecode
535.8 Other specified gastritis Digestive 0.99 0.913 – 1.08 0.8 638 6354 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.994 0.939 – 1.05 0.849 1255 12511 all phecode
536 Disorders of function of stomach Digestive 0.993 0.956 – 1.03 0.719 2911 27685 all phecode
536.3 Gastroparesis Digestive 1.02 0.943 – 1.1 0.65 706 6901 all phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.01 0.916 – 1.12 0.845 407 4059 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.988 0.946 – 1.03 0.604 2150 21094 all phecode
537 Other disorders of stomach and duodenum Digestive 1.03 0.99 – 1.07 0.15 3183 30048 all phecode
537.1 Lesions of stomach and duodenum Digestive 1.04 0.892 – 1.22 0.649 173 1725 all phecode
539 Bariatric surgery Digestive 0.979 0.929 – 1.03 0.418 1509 15074 all phecode
540 Appendiceal conditions Digestive 1.1 0.999 – 1.22 0.0567 495 4948 all phecode
540.1 Appendicitis Digestive 1.09 0.983 – 1.21 0.107 425 4239 all phecode
540.11 Acute appendicitis Digestive 1.08 0.965 – 1.21 0.191 353 3511 all phecode
550 Abdominal hernia Digestive 0.993 0.968 – 1.02 0.605 6768 37731 all phecode
550.1 Inguinal hernia Digestive 0.984 0.936 – 1.03 0.513 1744 16488 all phecode
550.2 Diaphragmatic hernia Digestive 0.995 0.957 – 1.03 0.792 2817 25849 all phecode
550.3 Femoral hernia Digestive 0.963 0.81 – 1.16 0.669 131 1291 all phecode
550.4 Umbilical hernia Digestive 0.983 0.93 – 1.04 0.544 1313 13110 all phecode
550.5 Ventral hernia Digestive 1.01 0.963 – 1.05 0.791 2241 22163 all phecode
550.6 Incisional hernia Digestive 1.02 0.967 – 1.09 0.41 1313 13111 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 0.998 0.948 – 1.05 0.948 1536 15153 all phecode
555.1 Regional enteritis Digestive 0.992 0.929 – 1.06 0.822 919 9095 all phecode
555.2 Ulcerative colitis Digestive 1.06 0.986 – 1.13 0.125 937 9315 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.09 0.991 – 1.19 0.0824 537 5315 all phecode
556 Ulceration of the lower GI tract Digestive 1 0.927 – 1.09 0.95 632 6267 all phecode
556.1 Ulceration of intestine Digestive 0.993 0.914 – 1.08 0.873 551 5451 all phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 1.03 0.893 – 1.2 0.671 214 2093 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.981 0.935 – 1.03 0.432 1716 16490 all phecode
557.1 Celiac disease Digestive 0.988 0.897 – 1.09 0.811 421 4026 all phecode
558 Noninfectious gastroenteritis Digestive 0.991 0.957 – 1.03 0.617 3458 26408 all phecode
559 Ileostomy status Digestive 1.03 0.96 – 1.1 0.448 957 9565 all phecode
560 Intestinal obstruction without mention of hernia Digestive 0.988 0.952 – 1.03 0.522 3004 24851 all phecode
560.1 Paralytic ileus Digestive 0.965 0.918 – 1.01 0.154 1627 15714 all phecode
560.2 Impaction of intestine Digestive 1.02 0.918 – 1.13 0.742 387 3779 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.95 0.844 – 1.08 0.409 266 2647 all phecode
560.4 Other intestinal obstruction Digestive 0.996 0.947 – 1.05 0.863 1651 16170 all phecode
561 Symptoms involving digestive system Digestive 1 0.964 – 1.05 0.848 2608 21766 all phecode
562 Diverticulosis and diverticulitis Digestive 1.02 0.992 – 1.05 0.162 6295 23431 all phecode
562.1 Diverticulosis Digestive 1.02 0.99 – 1.05 0.193 6246 23383 all phecode
562.2 Diverticulitis Digestive 1.05 0.998 – 1.11 0.0636 1611 15162 all phecode
564 Functional digestive disorders Digestive 1.01 0.984 – 1.03 0.616 11411 28676 all phecode
564.1 Irritable Bowel Syndrome Digestive 0.973 0.94 – 1.01 0.13 3457 22266 all phecode
564.9 Personal history of diseases of digestive system Digestive 1.01 0.974 – 1.05 0.55 3074 25861 all phecode
565 Anal and rectal conditions Digestive 1.01 0.971 – 1.04 0.741 3355 30757 all phecode
565.1 Anal and rectal polyp Digestive 1 0.945 – 1.06 0.991 1305 12649 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1 0.947 – 1.06 0.972 1364 13616 all phecode
568 Other disorders of peritoneum Digestive 1.05 0.998 – 1.11 0.0642 1705 17038 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.05 0.989 – 1.11 0.118 1247 12468 all phecode
569 Other disorders of intestine Digestive 1.02 0.991 – 1.04 0.209 8079 35231 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1 0.896 – 1.12 0.992 326 3260 all phecode
569.2 Gastrointestinal complications Digestive 1.03 0.973 – 1.09 0.329 1395 13933 all phecode
571 Chronic liver disease and cirrhosis Digestive 0.998 0.968 – 1.03 0.919 4610 32562 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 0.995 0.964 – 1.03 0.779 4342 32234 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.01 0.951 – 1.08 0.674 1018 10095 all phecode
571.6 Primary biliary cirrhosis Digestive 1 0.854 – 1.18 0.998 179 1790 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.02 0.955 – 1.09 0.536 950 9498 all phecode
571.81 Portal hypertension Digestive 1.02 0.934 – 1.11 0.683 573 5730 all phecode
572 Ascites (non malignant) Digestive 1 0.962 – 1.05 0.852 2278 22675 all phecode
573 Other disorders of liver Digestive 0.984 0.957 – 1.01 0.269 5599 33620 all phecode
573.1 Chronic passive congestion of liver Digestive 0.856 0.732 – 1.01 0.0583 136 1359 all phecode
573.2 Liver replaced by transplant Digestive 0.957 0.853 – 1.08 0.463 292 2920 all phecode
573.3 Hepatomegaly Digestive 1.01 0.92 – 1.11 0.864 470 4700 all phecode
573.4 Acute and subacute necrosis of liver Digestive 0.916 0.821 – 1.03 0.128 316 3149 all phecode
573.5 Jaundice (not of newborn) Digestive 0.99 0.927 – 1.06 0.765 958 9496 all phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.04 0.997 – 1.08 0.0696 2756 26470 all phecode
573.7 Abnormal results of function study of liver Digestive 1 0.964 – 1.04 0.941 3018 27774 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.01 0.979 – 1.04 0.557 4679 33866 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.02 0.983 – 1.06 0.301 3177 30809 all phecode
574.1 Cholelithiasis Digestive 1.02 0.981 – 1.06 0.326 2924 28874 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.11 0.989 – 1.26 0.0799 342 3412 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.02 0.932 – 1.11 0.713 553 5501 all phecode
574.2 Calculus of bile duct Digestive 1.01 0.939 – 1.08 0.836 852 8503 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.1 1.02 – 1.19 0.0156 822 8181 all phecode
575 Other biliary tract disease Digestive 0.992 0.95 – 1.04 0.71 2266 22555 all phecode
575.1 Cholangitis Digestive 0.932 0.839 – 1.04 0.192 354 3530 all phecode
575.2 Obstruction of bile duct Digestive 0.973 0.896 – 1.06 0.52 621 6201 all phecode
575.6 Cholesterolosis of gallbladder Digestive 0.905 0.793 – 1.04 0.147 207 2063 all phecode
575.7 Other disorders of gallbladder Digestive 1.03 0.962 – 1.1 0.412 939 9382 all phecode
575.8 Other disorders of biliary tract Digestive 0.969 0.913 – 1.03 0.298 1154 11523 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.11 0.967 – 1.27 0.149 260 2600 all phecode
577 Diseases of pancreas Digestive 0.989 0.947 – 1.03 0.626 2225 22106 all phecode
577.1 Acute pancreatitis Digestive 1 0.947 – 1.06 0.91 1212 12110 all phecode
577.2 Chronic pancreatitis Digestive 0.953 0.873 – 1.04 0.289 495 4950 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.974 0.897 – 1.06 0.54 570 5601 all phecode
578 Gastrointestinal hemorrhage Digestive 0.999 0.968 – 1.03 0.933 4554 37045 all phecode
578.1 Hematemesis Digestive 1.01 0.919 – 1.1 0.911 485 4842 all phecode
578.2 Blood in stool Digestive 0.991 0.953 – 1.03 0.653 2743 26554 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.02 0.975 – 1.06 0.413 2210 21750 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1 0.952 – 1.06 0.917 1562 15345 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1 0.971 – 1.03 0.891 4431 34209 all phecode
579.2 Splenomegaly Digestive 0.994 0.923 – 1.07 0.867 730 7262 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.96 0.91 – 1.01 0.131 1410 13877 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.02 0.974 – 1.08 0.355 1881 15516 all phecode
580.1 Glomerulonephritis Genitourinary 1.05 0.948 – 1.18 0.338 401 3992 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.17 0.978 – 1.42 0.093 146 1440 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.07 0.885 – 1.32 0.494 114 1128 all phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.21 0.911 – 1.64 0.201 61 600 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.01 0.893 – 1.15 0.861 277 2760 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.07 0.927 – 1.23 0.378 221 2193 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.04 0.978 – 1.1 0.234 1502 11930 all phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.04 0.967 – 1.12 0.313 992 7228 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.05 0.971 – 1.14 0.219 683 6612 all phecode
580.4 Renal sclerosis, NOS Genitourinary 0.978 0.873 – 1.1 0.703 340 3400 all phecode
585 Renal failure Genitourinary 1 0.975 – 1.03 0.966 7470 32340 all phecode
585.1 Acute renal failure Genitourinary 1 0.972 – 1.04 0.771 4265 27230 all phecode
585.2 Renal failure NOS Genitourinary 0.954 0.89 – 1.02 0.192 832 8162 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1 0.975 – 1.03 0.78 5580 29470 all phecode
585.31 Renal dialysis Genitourinary 0.977 0.908 – 1.05 0.547 747 7423 all phecode
585.32 End stage renal disease Genitourinary 0.974 0.914 – 1.04 0.42 1007 9783 all phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1 0.967 – 1.04 0.808 3209 21312 all phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 0.961 0.9 – 1.03 0.236 977 9190 all phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 0.978 0.922 – 1.04 0.474 1227 11191 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1 0.978 – 1.03 0.777 7628 34189 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.994 0.89 – 1.12 0.922 349 3480 all phecode
586.11 Small kidney Genitourinary 1.03 0.888 – 1.2 0.713 210 2093 all phecode
586.12 Vesicoureteral reflux Genitourinary 0.932 0.783 – 1.12 0.433 136 1360 all phecode
586.2 Cyst of kidney, acquired Genitourinary 0.96 0.91 – 1.01 0.144 1381 12912 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.02 0.87 – 1.2 0.84 187 1862 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.01 0.966 – 1.06 0.589 1821 17115 all phecode
587 Kidney replaced by transpant Genitourinary 0.955 0.891 – 1.03 0.208 819 8134 all phecode
588 Disorders resulting from impaired renal function Genitourinary 0.998 0.935 – 1.07 0.947 976 9389 all phecode
588.1 Renal osteodystrophy Genitourinary 1.02 0.904 – 1.16 0.752 290 2900 all phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 0.996 0.926 – 1.07 0.911 755 7275 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.02 0.96 – 1.09 0.472 1007 9834 all phecode
590 Pyelonephritis Genitourinary 1.07 1.01 – 1.13 0.0215 1461 14350 all phecode
591 Urinary tract infection Genitourinary 1.01 0.986 – 1.03 0.465 9873 32513 all phecode
592 Cystitis and urethritis Genitourinary 1.03 0.987 – 1.07 0.196 3038 24207 all phecode
592.1 Cystitis Genitourinary 1.03 0.988 – 1.07 0.182 2880 23279 all phecode
592.11 Acute cystitis Genitourinary 1.03 0.983 – 1.09 0.204 1783 16452 all phecode
592.12 Chronic cystitis Genitourinary 0.988 0.867 – 1.14 0.864 239 2343 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.992 0.903 – 1.09 0.874 431 4310 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.974 0.852 – 1.12 0.712 210 2093 all phecode
593 Hematuria Genitourinary 1.01 0.982 – 1.04 0.431 4859 32063 all phecode
593.1 Gross hematuria Genitourinary 1.02 0.971 – 1.08 0.387 1585 14824 all phecode
593.2 Microscopic hematuria Genitourinary 1 0.94 – 1.07 0.994 1049 10301 all phecode
594 Urinary calculus Genitourinary 1.01 0.988 – 1.04 0.284 6707 38209 all phecode
594.1 Calculus of kidney Genitourinary 1.02 0.991 – 1.05 0.192 6273 38051 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.07 0.96 – 1.2 0.226 366 3638 all phecode
594.3 Calculus of ureter Genitourinary 1.05 0.99 – 1.11 0.111 1361 13561 all phecode
594.8 Renal colic Genitourinary 1.04 0.933 – 1.16 0.505 356 3560 all phecode
595 Hydronephrosis Genitourinary 1.02 0.973 – 1.08 0.37 1670 16658 all phecode
596 Other disorders of bladder Genitourinary 1.02 0.979 – 1.06 0.409 3074 28020 all phecode
596.1 Bladder neck obstruction Genitourinary 1.01 0.914 – 1.13 0.788 400 3942 all phecode
596.5 Functional disorders of bladder Genitourinary 1 0.955 – 1.06 0.871 1719 17049 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.962 0.909 – 1.02 0.195 1211 11998 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.938 0.871 – 1.01 0.0891 661 6537 all phecode
597.2 Urinary complications NEC Genitourinary 1.01 0.948 – 1.08 0.752 1049 10479 all phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.07 0.92 – 1.27 0.375 189 1873 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.1 0.927 – 1.33 0.282 138 1356 all phecode
598.4 Other cells and casts in urine Genitourinary 1.07 0.889 – 1.31 0.492 122 1192 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.988 – 1.03 0.429 14168 30681 all phecode
599.1 Urinary obstruction Genitourinary 0.95 0.882 – 1.02 0.177 728 6861 all phecode
599.2 Retention of urine Genitourinary 0.989 0.959 – 1.02 0.473 5034 28305 all phecode
599.3 Dysuria Genitourinary 1.01 0.979 – 1.04 0.517 4397 27849 all phecode
599.4 Urinary incontinence Genitourinary 0.996 0.967 – 1.03 0.778 5599 26960 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1.02 0.992 – 1.05 0.165 5498 28723 all phecode
599.6 Oliguria and anuria Genitourinary 0.91 0.841 – 0.987 0.0211 599 5902 all phecode
599.7 Urethral discharge Genitourinary 1.03 0.856 – 1.25 0.777 118 1175 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1 0.974 – 1.03 0.827 5446 27963 all phecode
599.9 Other abnormality of urination Genitourinary 1.03 0.994 – 1.07 0.106 3041 24877 all phecode
600 Hyperplasia of prostate Genitourinary 0.972 0.936 – 1.01 0.146 4063 11364 all phecode
601 Inflammatory diseases of prostate Genitourinary 1.01 0.943 – 1.07 0.876 1044 9665 all phecode
601.1 Prostatitis Genitourinary 0.972 0.888 – 1.07 0.541 477 4596 all phecode
601.11 Acute prostatitis Genitourinary 0.967 0.82 – 1.16 0.699 124 1200 all phecode
601.12 Chronic prostatitis Genitourinary 0.874 0.728 – 1.06 0.158 95 943 all phecode
601.3 Orchitis and epididymitis Genitourinary 0.938 0.851 – 1.04 0.205 389 3822 all phecode
601.4 Balanoposthitis Genitourinary 0.991 0.828 – 1.2 0.92 127 1224 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.997 0.851 – 1.18 0.975 161 1591 all phecode
602 Other disorders of prostate Genitourinary 0.965 0.871 – 1.07 0.502 361 3399 all phecode
602.3 Dysplasia of prostate Genitourinary 1 0.797 – 1.29 0.97 77 730 all phecode
603 Other disorders of testis Genitourinary 1.02 0.924 – 1.12 0.727 440 4354 all phecode
603.1 Hydrocele Genitourinary 1.04 0.923 – 1.18 0.509 293 2882 all phecode
603.2 Spermatocele Genitourinary 1.01 0.859 – 1.2 0.918 156 1539 all phecode
604 Disorders of penis Genitourinary 1.05 0.974 – 1.14 0.197 685 6748 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.05 0.886 – 1.25 0.586 155 1540 all phecode
604.3 Peyronie's disease Genitourinary 1.05 0.909 – 1.22 0.519 215 2132 all phecode
605 Erectile dysfunction [ED] Genitourinary 1.03 0.992 – 1.07 0.125 3776 12700 all phecode
608 Other disorders of male genital organs Genitourinary 0.995 0.946 – 1.05 0.854 1645 13758 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.01 0.913 – 1.12 0.861 424 4196 all phecode
609.1 Infertility, male Genitourinary 1.01 0.898 – 1.14 0.866 302 2992 all phecode
609.11 Azoospermia and oligospermia Genitourinary 0.891 0.727 – 1.11 0.274 95 950 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.979 0.83 – 1.17 0.802 154 1519 all phecode
610 Benign mammary dysplasias Genitourinary 0.97 0.936 – 1.01 0.0924 3683 16548 all phecode
610.1 Cystic mastopathy Genitourinary 0.927 0.883 – 0.973 0.00219 1633 14191 all phecode
610.2 Fibroadenosis of breast Genitourinary 0.906 0.719 – 1.17 0.416 60 600 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.989 0.95 – 1.03 0.592 2837 16430 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.925 0.877 – 0.978 0.00514 1269 12191 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.988 0.959 – 1.02 0.417 6067 18690 all phecode
611.1 Abnormal mammogram Genitourinary 0.987 0.956 – 1.02 0.419 4980 16120 all phecode
611.11 Mammographic microcalcification Genitourinary 0.97 0.913 – 1.03 0.33 1122 10394 all phecode
611.3 Lump or mass in breast Genitourinary 0.982 0.948 – 1.02 0.317 3549 18572 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.98 0.921 – 1.04 0.516 1051 10425 all phecode
612.1 Galactorrhea Genitourinary 0.971 0.831 – 1.15 0.72 139 1390 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.965 0.899 – 1.04 0.329 800 7962 all phecode
612.3 Congenital anomalies of breast Genitourinary 1.07 0.863 – 1.36 0.57 83 810 all phecode
613 Other nonmalignant breast conditions Genitourinary 0.983 0.95 – 1.02 0.325 3897 22072 all phecode
613.1 Inflammatory disease of breast Genitourinary 0.964 0.89 – 1.05 0.371 593 5874 all phecode
613.5 Mastodynia Genitourinary 0.953 0.909 – 1 0.054 1675 16203 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.978 0.914 – 1.05 0.534 883 8754 all phecode
613.8 Other specified disorders of breast Genitourinary 0.973 0.912 – 1.04 0.411 932 9248 all phecode
613.9 Breast disorder NOS Genitourinary 0.99 0.939 – 1.04 0.702 1465 14174 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.02 0.989 – 1.06 0.179 3715 19647 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.97 0.868 – 1.09 0.597 337 3370 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.14 1.04 – 1.27 0.00887 478 4773 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.35 1.06 – 1.75 0.0184 94 933 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.1 0.935 – 1.3 0.264 186 1842 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.09 0.956 – 1.26 0.202 246 2460 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.999 0.857 – 1.18 0.995 165 1639 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.01 0.974 – 1.05 0.568 3180 19539 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.11 0.975 – 1.27 0.123 264 2640 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.01 0.966 – 1.05 0.788 2732 18924 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.17 0.975 – 1.43 0.098 132 1311 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.975 0.859 – 1.11 0.698 225 2244 all phecode
615 Endometriosis Genitourinary 0.993 0.944 – 1.05 0.802 1585 14666 all phecode
618 Genital prolapse Genitourinary 1.01 0.967 – 1.06 0.624 2079 17915 all phecode
618.1 Prolapse of vaginal walls Genitourinary 0.993 0.94 – 1.05 0.803 1408 13456 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.12 1.02 – 1.24 0.019 542 5390 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.09 0.965 – 1.23 0.178 317 3162 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.02 0.928 – 1.13 0.648 441 4394 all phecode
619 Noninflammatory female genital disorders Genitourinary 1.02 0.989 – 1.05 0.229 5728 18687 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.06 1 – 1.13 0.0484 1233 12082 all phecode
619.2 Disorders of uterus, NEC Genitourinary 0.97 0.893 – 1.06 0.47 591 5897 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.996 0.912 – 1.09 0.927 483 4823 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.03 0.986 – 1.07 0.201 2525 18404 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.991 0.935 – 1.05 0.775 1189 11717 all phecode
620 Dysplasia of female genital organs Genitourinary 1.02 0.922 – 1.13 0.735 395 3950 all phecode
620.1 Dysplasia of cervix Genitourinary 1.02 0.886 – 1.18 0.819 178 1780 all phecode
621 Endometrial hyperplasia Genitourinary 1.11 0.998 – 1.23 0.059 437 4370 all phecode
622 Polyp of female genital organs Genitourinary 0.991 0.94 – 1.05 0.756 1449 14264 all phecode
622.1 Polyp of corpus uteri Genitourinary 1.01 0.954 – 1.08 0.647 1132 11189 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.923 0.844 – 1.01 0.0882 445 4444 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.03 0.959 – 1.11 0.414 824 8165 all phecode
624 Symptoms involving female genital tract Genitourinary 1.02 0.967 – 1.08 0.441 1348 12518 all phecode
624.1 Dystrophy of female genital tract Genitourinary 1.04 0.902 – 1.2 0.616 216 2155 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.959 0.749 – 1.26 0.749 64 615 all phecode
624.9 stress incontinence, female Genitourinary 1.04 0.989 – 1.09 0.139 1935 15408 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.01 0.977 – 1.04 0.685 5653 17303 all phecode
625.1 Dyspareunia Genitourinary 1.02 0.962 – 1.08 0.528 1267 12474 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.04 1.01 – 1.07 0.0194 5940 15585 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.05 1.01 – 1.09 0.00882 4315 14604 all phecode
626.11 Absent or infrequent menstruation Genitourinary 1.09 1.02 – 1.16 0.0147 1062 8531 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.04 0.994 – 1.09 0.0909 2097 11991 all phecode
626.13 Irregular menstrual cycle Genitourinary 1.03 0.983 – 1.08 0.212 1957 12265 all phecode
626.14 Irregular menstrual bleeding Genitourinary 1.08 1.01 – 1.16 0.032 970 8996 all phecode
626.15 Infertility, female, associated with anovulation Genitourinary 1.12 1.01 – 1.26 0.0421 394 3789 all phecode
626.2 Dysmenorrhea Genitourinary 1.05 0.993 – 1.12 0.0872 1373 9857 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.962 0.87 – 1.07 0.455 336 3308 all phecode
626.8 Infertility, female Genitourinary 1.06 0.989 – 1.15 0.0992 817 6741 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.02 0.987 – 1.06 0.222 4560 14557 all phecode
627.1 Postmenopausal bleeding Genitourinary 1 0.945 – 1.07 0.897 1146 10338 all phecode
627.2 Symptomatic menopause Genitourinary 1.02 0.981 – 1.06 0.32 3017 13763 all phecode
627.21 Symptomatic artificial menopause Genitourinary 0.984 0.85 – 1.15 0.83 152 1514 all phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.904 0.821 – 0.999 0.0427 356 3513 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.01 0.95 – 1.08 0.685 997 9484 all phecode
627.4 Premenopausal menorrhagia Genitourinary 1.03 0.923 – 1.15 0.629 361 3580 all phecode
627.5 Premature menopause and other ovarian failure Genitourinary 1.04 0.931 – 1.18 0.473 309 3082 all phecode
628 Ovarian cyst Genitourinary 1.03 0.982 – 1.08 0.228 1945 13838 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.04 0.965 – 1.11 0.337 826 8047 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.16 1.02 – 1.33 0.0317 273 2715 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.934 0.791 – 1.12 0.441 117 1170 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.05 0.966 – 1.15 0.252 563 5309 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.06 0.952 – 1.18 0.297 370 3629 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.04 0.923 – 1.17 0.544 288 2850 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.04 0.977 – 1.11 0.222 1080 7870 all phecode
636.1 Threatened premature labor Pregnancy Complications 1.03 0.931 – 1.15 0.546 380 3799 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.952 0.851 – 1.07 0.408 288 2868 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.09 0.985 – 1.21 0.102 441 4365 all phecode
636.8 Cervical incompetence Pregnancy Complications 0.958 0.788 – 1.19 0.683 77 770 all phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 0.739 0.609 – 0.906 0.00271 85 850 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.02 0.937 – 1.11 0.692 585 5725 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.03 0.919 – 1.16 0.643 302 3013 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.03 0.909 – 1.18 0.624 252 2506 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.977 0.825 – 1.17 0.789 119 1190 all phecode
644 Anemia during pregnancy Pregnancy Complications 0.979 0.857 – 1.13 0.762 224 2224 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.05 0.976 – 1.13 0.205 855 6531 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.998 0.874 – 1.15 0.976 211 2093 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.937 0.826 – 1.07 0.327 222 2213 all phecode
647.3 Major puerperal infection Pregnancy Complications 0.993 0.778 – 1.3 0.954 65 650 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.04 0.978 – 1.1 0.222 1275 8010 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.995 0.92 – 1.08 0.894 649 5687 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.05 0.96 – 1.14 0.315 587 5463 all phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.906 0.8 – 1.03 0.129 207 2055 all phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 1.05 0.912 – 1.22 0.501 204 2040 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.08 1.02 – 1.14 0.00595 1624 10064 all phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 1.09 1.01 – 1.19 0.0401 616 5533 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.05 0.98 – 1.13 0.164 898 7014 all phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 1.23 0.938 – 1.66 0.138 66 660 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.01 0.945 – 1.08 0.75 887 6802 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.14 0.99 – 1.33 0.0741 236 2351 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.04 0.886 – 1.22 0.666 158 1580 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.08 0.931 – 1.27 0.313 184 1814 all phecode
681 Superficial cellulitis and abscess Dermatologic 1 0.978 – 1.03 0.737 6500 38394 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.973 0.918 – 1.03 0.366 1256 11462 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.953 0.894 – 1.02 0.137 1007 9981 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.993 0.949 – 1.04 0.745 2123 19952 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.02 0.974 – 1.06 0.444 2252 20944 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.01 0.958 – 1.06 0.786 1820 16893 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.02 0.965 – 1.07 0.546 1572 15588 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 0.982 0.941 – 1.03 0.405 2257 21750 all phecode
686.1 Carbuncle and furuncle Dermatologic 0.975 0.899 – 1.06 0.549 558 5504 all phecode
686.2 Impetigo Dermatologic 1.07 0.96 – 1.19 0.243 414 4117 all phecode
686.3 Pilonidal cyst Dermatologic 0.966 0.829 – 1.14 0.671 160 1594 all phecode
686.4 Pyogenic granuloma Dermatologic 0.921 0.792 – 1.08 0.292 158 1570 all phecode
686.5 Pyoderma Dermatologic 0.932 0.738 – 1.21 0.566 63 630 all phecode
687 Symptoms affecting skin Dermatologic 1.02 0.973 – 1.08 0.362 1690 16343 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.01 0.984 – 1.04 0.445 7007 34623 all phecode
687.3 Changes in skin texture Dermatologic 0.939 0.851 – 1.04 0.213 415 4121 all phecode
687.4 Disturbance of skin sensation Dermatologic 0.985 0.959 – 1.01 0.263 6375 34216 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1 0.98 – 1.03 0.807 9311 37335 all phecode
690 Erythematosquamous dermatosis Dermatologic 1.01 0.98 – 1.04 0.529 5184 31581 all phecode
690.1 Seborrheic dermatitis Dermatologic 1.01 0.981 – 1.04 0.505 5174 31553 all phecode
691 Congenital anomalies of skin Dermatologic 1.03 0.947 – 1.13 0.459 541 5337 all phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 1.02 0.795 – 1.36 0.872 62 613 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.998 0.952 – 1.05 0.941 1861 17936 all phecode
694.1 Vitiligo Dermatologic 0.901 0.77 – 1.07 0.206 137 1347 all phecode
694.2 Other dyschromia Dermatologic 1.02 0.969 – 1.07 0.479 1674 16183 all phecode
694.3 Vascular disorders of skin Dermatologic 0.891 0.738 – 1.09 0.24 82 819 all phecode
695 Erythematous conditions Dermatologic 1.02 0.985 – 1.05 0.282 4120 30247 all phecode
695.1 Toxic erythema Dermatologic 1.06 0.838 – 1.38 0.623 70 688 all phecode
695.2 Bullous dermatoses Dermatologic 1.01 0.816 – 1.27 0.93 85 805 all phecode
695.3 Rosacea Dermatologic 0.978 0.933 – 1.03 0.357 1816 17663 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.09 1 – 1.18 0.0513 672 6686 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.2 1.05 – 1.39 0.0101 247 2437 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.1 1.01 – 1.2 0.0291 637 6337 all phecode
695.7 Prurigo and Lichen Dermatologic 1.06 0.972 – 1.15 0.198 605 5986 all phecode
695.8 Other specified erythematous conditions Dermatologic 1.05 0.977 – 1.14 0.181 812 7980 all phecode
695.81 Erythema nodosum Dermatologic 1.04 0.801 – 1.42 0.76 55 550 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.06 0.978 – 1.15 0.162 679 6756 all phecode
696 Psoriasis and related disorders Dermatologic 1.07 1.01 – 1.13 0.0218 1401 13832 all phecode
696.3 Pityriasis Dermatologic 1.16 0.931 – 1.47 0.193 92 904 all phecode
696.4 Psoriasis Dermatologic 1.06 1 – 1.13 0.053 1311 12976 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.06 0.994 – 1.12 0.08 1200 11867 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.08 0.957 – 1.24 0.213 282 2810 all phecode
697 Sarcoidosis Dermatologic 1.07 0.953 – 1.2 0.271 333 3330 all phecode
698 Pruritus and related conditions Dermatologic 0.999 0.957 – 1.04 0.956 2254 21889 all phecode
700 Corns and callosities Dermatologic 1.01 0.957 – 1.08 0.63 1373 10894 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1 0.979 – 1.03 0.785 7651 38050 all phecode
701.1 Keratoderma, acquired Dermatologic 1.04 0.951 – 1.14 0.405 567 5524 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.992 0.949 – 1.04 0.71 2184 21550 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.01 0.923 – 1.1 0.864 571 5660 all phecode
701.4 Keloid scar Dermatologic 1.02 0.942 – 1.11 0.596 578 5716 all phecode
701.5 Abnormal granulation tissue Dermatologic 1.04 0.936 – 1.15 0.508 400 3982 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.99 0.963 – 1.02 0.446 6956 29525 all phecode
702.1 Actinic keratosis Dermatologic 0.975 0.943 – 1.01 0.127 4171 26529 all phecode
702.2 Seborrheic keratosis Dermatologic 0.994 0.965 – 1.02 0.679 5480 31552 all phecode
702.4 Degenerative skin disorders Dermatologic 0.939 0.757 – 1.19 0.579 86 832 all phecode
703 Diseases of nail, NOS Dermatologic 0.96 0.914 – 1.01 0.114 1650 14562 all phecode
703.1 Ingrowing nail Dermatologic 0.989 0.925 – 1.06 0.747 920 8597 all phecode
704 Diseases of hair and hair follicles Dermatologic 1.02 0.98 – 1.06 0.387 3118 29542 all phecode
704.1 Alopecia Dermatologic 1.01 0.961 – 1.07 0.61 1408 13871 all phecode
704.11 Alopecia Areata Dermatologic 1.1 0.863 – 1.41 0.458 82 811 all phecode
704.12 Telogen effluvium Dermatologic 1.43 1.05 – 1.98 0.0234 63 615 all phecode
704.2 Hirsutism Dermatologic 1.08 0.953 – 1.23 0.239 299 2946 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.01 0.963 – 1.06 0.663 1752 17189 all phecode
705 Disorders of sweat glands Dermatologic 0.925 0.857 – 1 0.0512 603 6012 all phecode
705.1 Dyshidrosis Dermatologic 0.991 0.85 – 1.17 0.914 154 1540 all phecode
705.3 Hidradenitis Dermatologic 0.827 0.733 – 0.937 0.00226 245 2440 all phecode
705.8 Hyperhidrosis Dermatologic 1.01 0.954 – 1.08 0.657 1112 10986 all phecode
706 Diseases of sebaceous glands Dermatologic 1.01 0.985 – 1.04 0.393 5995 39748 all phecode
706.1 Acne Dermatologic 1.02 0.98 – 1.06 0.321 2594 22570 all phecode
706.2 Sebaceous cyst Dermatologic 1.01 0.974 – 1.05 0.518 2814 26819 all phecode
706.3 Seborrhea Dermatologic 0.973 0.746 – 1.31 0.847 59 582 all phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.978 0.93 – 1.03 0.393 1684 15289 all phecode
707 Chronic ulcer of skin Dermatologic 1.03 0.992 – 1.07 0.125 2871 26816 all phecode
707.1 Decubitus ulcer Dermatologic 1.01 0.944 – 1.09 0.714 825 8119 all phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.04 0.977 – 1.11 0.223 1108 9992 all phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1.02 0.971 – 1.08 0.402 1641 16172 all phecode
709 Diffuse diseases of connective tissue Dermatologic 1.03 0.974 – 1.09 0.311 1477 14427 all phecode
709.2 Sicca syndrome Dermatologic 1.03 0.942 – 1.14 0.507 505 4986 all phecode
709.3 Systemic sclerosis Dermatologic 0.961 0.839 – 1.11 0.569 224 2209 all phecode
709.5 Dermatomyositis Dermatologic 0.93 0.759 – 1.16 0.497 92 892 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.03 0.829 – 1.31 0.795 90 892 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.07 0.996 – 1.15 0.0693 917 9089 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.01 0.949 – 1.07 0.85 1254 12103 all phecode
710.1 Osteomyelitis Musculoskeletal 1.01 0.95 – 1.07 0.811 1203 11636 all phecode
710.11 Acute osteomyelitis Musculoskeletal 1.03 0.946 – 1.12 0.505 590 5708 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.03 0.946 – 1.13 0.49 531 5163 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.01 0.955 – 1.08 0.638 1153 11149 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.06 0.959 – 1.18 0.255 410 4099 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.05 0.932 – 1.19 0.424 290 2900 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.02 0.876 – 1.19 0.821 178 1776 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.03 0.917 – 1.16 0.641 314 3028 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.04 0.895 – 1.22 0.625 194 1824 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 0.982 0.939 – 1.03 0.418 2086 18159 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.969 0.923 – 1.02 0.211 1670 15087 all phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 1.13 0.886 – 1.47 0.346 77 767 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.987 0.932 – 1.05 0.647 1209 11967 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.999 0.888 – 1.13 0.988 262 2611 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.961 0.843 – 1.1 0.564 219 2182 all phecode
716 Other arthropathies Musculoskeletal 1.01 0.985 – 1.03 0.568 13482 31305 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.95 0.824 – 1.1 0.483 192 1920 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.03 0.852 – 1.25 0.79 131 1293 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.01 0.986 – 1.03 0.511 13410 31294 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.974 0.863 – 1.11 0.681 261 2565 all phecode
720 Spinal stenosis Musculoskeletal 0.969 0.937 – 1 0.0608 3958 28539 all phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1 0.962 – 1.04 0.998 2872 23656 all phecode
721 Spondylosis and allied disorders Musculoskeletal 0.98 0.952 – 1.01 0.175 5509 32391 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.98 0.952 – 1.01 0.189 5153 31896 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.01 0.942 – 1.09 0.773 867 8629 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1 0.884 – 1.14 0.996 262 2600 all phecode
722 Intervertebral disc disorders Musculoskeletal 0.995 0.969 – 1.02 0.728 6284 34317 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.981 0.948 – 1.02 0.27 3591 31411 all phecode
722.3 Schmorl's nodes Musculoskeletal 0.918 0.786 – 1.09 0.299 126 1248 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1 0.972 – 1.04 0.781 3957 30744 all phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.01 0.92 – 1.1 0.91 515 5140 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.02 0.922 – 1.14 0.687 397 3968 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.976 0.932 – 1.02 0.303 1932 19288 all phecode
723 Other disorders of cervical region Musculoskeletal 1.03 0.96 – 1.1 0.462 952 9495 all phecode
723.1 Torticollis Musculoskeletal 1.01 0.892 – 1.15 0.876 254 2522 all phecode
724 Other and unspecified disorders of back Musculoskeletal 0.992 0.961 – 1.03 0.651 4130 31954 all phecode
724.1 Disorders of sacrum Musculoskeletal 0.975 0.935 – 1.02 0.254 2307 21902 all phecode
724.2 Disorders of coccyx Musculoskeletal 0.918 0.836 – 1.01 0.0745 426 4215 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.05 0.977 – 1.12 0.194 931 9295 all phecode
724.9 Other unspecified back disorders Musculoskeletal 0.991 0.939 – 1.05 0.737 1412 14087 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.998 0.975 – 1.02 0.864 9917 30176 all phecode
726.1 Enthesopathy Musculoskeletal 0.994 0.969 – 1.02 0.643 7507 30106 all phecode
726.2 Synoviopathy Musculoskeletal 1.03 0.962 – 1.1 0.428 1015 9987 all phecode
726.3 Bursitis Musculoskeletal 0.996 0.949 – 1.05 0.861 1829 16722 all phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 1 0.944 – 1.06 0.963 1193 11485 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.995 0.97 – 1.02 0.713 7425 30105 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.983 0.947 – 1.02 0.353 3092 24998 all phecode
727.2 Bursitis disorders Musculoskeletal 1.05 0.949 – 1.17 0.351 419 4112 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.978 0.927 – 1.03 0.412 1400 13621 all phecode
727.5 Rupture of synovium Musculoskeletal 1 0.913 – 1.11 0.951 480 4672 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.983 0.943 – 1.03 0.426 2461 21948 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.01 0.929 – 1.1 0.817 591 5893 all phecode
727.8 Plica syndrome Musculoskeletal 1.11 0.934 – 1.35 0.24 130 1264 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.993 0.963 – 1.03 0.676 4546 29473 all phecode
728.1 Muscular calcification and ossification Musculoskeletal 0.814 0.667 – 1.01 0.0475 85 843 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.895 0.804 – 1 0.0448 297 2949 all phecode
728.7 Fasciitis Musculoskeletal 1.01 0.967 – 1.05 0.777 2814 23463 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.994 0.899 – 1.1 0.904 419 4138 all phecode
729 Other disorders of soft tissues Musculoskeletal 0.99 0.956 – 1.03 0.571 3642 27471 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.862 0.681 – 1.12 0.233 74 726 all phecode
729.3 Panniculitis Musculoskeletal 0.947 0.794 – 1.14 0.553 119 1174 all phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 1.11 0.86 – 1.48 0.442 67 664 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.955 0.836 – 1.1 0.51 210 2091 all phecode
732 Osteochondropathies Musculoskeletal 0.912 0.824 – 1.02 0.0845 361 3604 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.895 0.783 – 1.03 0.114 198 1969 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.914 0.748 – 1.14 0.396 90 882 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.998 0.967 – 1.03 0.904 4543 26941 all phecode
733.2 Cyst of bone Musculoskeletal 0.985 0.849 – 1.15 0.845 190 1900 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.952 0.873 – 1.04 0.268 518 5160 all phecode
733.6 Costochondritis Musculoskeletal 0.981 0.881 – 1.1 0.731 357 3562 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.991 0.924 – 1.07 0.814 822 8205 all phecode
733.9 Chondromalacia Musculoskeletal 0.779 0.641 – 0.957 0.0141 96 960 all phecode
735 Acquired foot deformities Musculoskeletal 1.01 0.971 – 1.04 0.737 3417 29622 all phecode
735.1 Flat foot Musculoskeletal 1 0.925 – 1.09 0.935 620 6092 all phecode
735.2 Acquired toe deformities Musculoskeletal 0.987 0.933 – 1.05 0.659 1323 11983 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.983 0.914 – 1.06 0.655 825 7494 all phecode
735.23 Hallux rigidus Musculoskeletal 0.952 0.862 – 1.06 0.338 405 4005 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.03 0.978 – 1.09 0.248 1470 14295 all phecode
736 Other acquired deformities of limbs Musculoskeletal 1.03 0.99 – 1.07 0.145 2763 26555 all phecode
736.1 Acquired deformities of forearm Musculoskeletal 1.13 0.909 – 1.43 0.291 104 1033 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1.07 0.925 – 1.26 0.355 215 2142 all phecode
736.3 Acquired deformities of hip Musculoskeletal 0.891 0.705 – 1.16 0.354 60 590 all phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.986 0.879 – 1.11 0.812 325 3247 all phecode
736.5 Acquired deformities of knee Musculoskeletal 0.942 0.834 – 1.07 0.348 246 2460 all phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.984 0.884 – 1.1 0.778 339 3365 all phecode
737 Curvature of spine Musculoskeletal 0.998 0.948 – 1.05 0.94 1566 15543 all phecode
737.1 Kyphosis (acquired) Musculoskeletal 0.962 0.879 – 1.06 0.403 479 4748 all phecode
737.2 Lordosis (acquired) Musculoskeletal 1.23 0.944 – 1.64 0.133 70 700 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.01 0.951 – 1.07 0.794 1203 11982 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.03 0.991 – 1.08 0.124 2443 24187 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1 0.94 – 1.07 0.99 1057 10542 all phecode
739 Contracture of joint Musculoskeletal 0.985 0.91 – 1.07 0.718 621 6207 all phecode
740 Osteoarthrosis Musculoskeletal 1 0.98 – 1.02 0.987 16169 30268 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.02 0.991 – 1.05 0.188 7005 27422 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.02 0.992 – 1.05 0.156 6176 26155 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.999 0.927 – 1.08 0.976 713 7116 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.01 0.955 – 1.06 0.84 1609 12092 all phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 1.01 0.911 – 1.13 0.83 373 3586 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1 0.982 – 1.02 0.828 15497 30141 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1 0.977 – 1.03 0.941 8555 35884 all phecode
741.1 Ankylosis of joint Musculoskeletal 0.972 0.858 – 1.11 0.662 245 2445 all phecode
741.2 Stiffness of joint Musculoskeletal 0.974 0.921 – 1.03 0.37 1268 12594 all phecode
741.3 Difficulty in walking Musculoskeletal 1 0.962 – 1.04 0.919 2558 23116 all phecode
741.4 Joint effusions Musculoskeletal 0.999 0.959 – 1.04 0.969 2493 24199 all phecode
741.5 Hemarthrosis Musculoskeletal 1.12 0.913 – 1.4 0.291 94 937 all phecode
741.6 Villonodular synovitis Musculoskeletal 1 0.782 – 1.32 0.976 68 666 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.998 0.967 – 1.03 0.879 4404 33771 all phecode
742.1 Loose body in joint Musculoskeletal 1.05 0.89 – 1.25 0.573 156 1554 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.927 0.829 – 1.04 0.189 280 2792 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.01 0.897 – 1.15 0.851 245 2450 all phecode
742.9 Other derangement of joint Musculoskeletal 1.01 0.974 – 1.04 0.734 4107 32972 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.994 0.97 – 1.02 0.611 9223 36921 all phecode
743.1 Osteoporosis Musculoskeletal 0.997 0.962 – 1.04 0.893 3712 19477 all phecode
743.11 Osteoporosis NOS Musculoskeletal 1 0.966 – 1.04 0.921 3657 19276 all phecode
743.12 Senile osteoporosis Musculoskeletal 0.984 0.909 – 1.07 0.687 703 5804 all phecode
743.13 Other specified osteoporosis Musculoskeletal 0.954 0.858 – 1.07 0.387 321 3141 all phecode
743.2 Pathologic fracture Musculoskeletal 0.971 0.914 – 1.03 0.334 1112 10563 all phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 1.03 0.934 – 1.13 0.595 475 4629 all phecode
743.22 Pathologic fracture of femur Musculoskeletal 1.01 0.853 – 1.2 0.927 143 1391 all phecode
743.4 Stress fracture Musculoskeletal 1.05 0.944 – 1.16 0.403 407 4046 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1 0.974 – 1.03 0.975 6970 35237 all phecode
745 Pain in joint Musculoskeletal 1 0.983 – 1.02 0.914 19848 26918 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.998 0.956 – 1.04 0.918 2236 22256 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.997 0.95 – 1.05 0.903 1767 17598 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.956 0.884 – 1.04 0.268 650 6497 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.982 0.913 – 1.06 0.628 751 7480 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.06 0.96 – 1.19 0.242 410 4090 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.03 0.939 – 1.13 0.54 501 5010 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.14 0.929 – 1.43 0.216 111 1110 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.927 0.854 – 1.01 0.0756 555 5549 all phecode
749.1 Cleft palate Congenital Anomalies 0.907 0.757 – 1.1 0.307 97 970 all phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.914 0.774 – 1.1 0.309 105 1041 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.976 0.912 – 1.05 0.485 893 8919 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.959 0.863 – 1.07 0.447 366 3655 all phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.895 0.756 – 1.08 0.213 119 1185 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.03 0.841 – 1.27 0.812 99 982 all phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 0.963 0.807 – 1.16 0.687 134 1332 all phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 0.966 0.727 – 1.32 0.818 60 593 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.957 0.878 – 1.05 0.327 531 5300 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1 0.895 – 1.13 0.947 313 3129 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.902 0.792 – 1.03 0.125 222 2214 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.992 0.948 – 1.04 0.715 2008 19975 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.04 0.95 – 1.14 0.416 574 5740 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1 0.905 – 1.12 0.935 384 3840 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.05 0.89 – 1.26 0.549 153 1527 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.956 0.906 – 1.01 0.103 1379 13704 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.981 0.919 – 1.05 0.569 976 9685 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.911 0.819 – 1.02 0.092 294 2927 all phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1 0.869 – 1.16 1 182 1809 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.02 0.962 – 1.09 0.496 1133 11313 all phecode
752.1 Neural tube defects Congenital Anomalies 1.02 0.957 – 1.1 0.509 923 9209 all phecode
752.11 Spina bifida Congenital Anomalies 1.04 0.897 – 1.21 0.631 176 1760 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.02 0.893 – 1.18 0.768 232 2320 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.906 0.795 – 1.04 0.145 207 2051 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.806 0.637 – 1.04 0.0817 58 580 all phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 0.895 0.701 – 1.17 0.39 56 546 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1 0.944 – 1.06 0.989 1216 12116 all phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 1.05 0.876 – 1.27 0.627 135 1333 all phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 0.993 0.911 – 1.09 0.881 558 5570 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.03 0.952 – 1.11 0.514 747 7458 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.02 0.919 – 1.14 0.718 368 3663 all phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 1.16 0.912 – 1.52 0.247 74 740 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.05 0.935 – 1.18 0.422 321 3205 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.12 0.958 – 1.33 0.161 185 1847 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.03 0.977 – 1.09 0.264 1358 13579 all phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 1.12 0.879 – 1.48 0.373 68 680 all phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 0.974 0.773 – 1.25 0.829 71 694 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.09 0.966 – 1.23 0.174 335 3346 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.03 0.964 – 1.1 0.396 1003 10014 all phecode
757 Congenital anomalies of the integument Congenital Anomalies 1 0.906 – 1.12 0.947 401 4001 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.08 0.933 – 1.26 0.313 185 1845 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 1 0.847 – 1.2 0.996 135 1349 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.02 0.94 – 1.11 0.62 557 5566 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.903 0.73 – 1.14 0.364 71 710 all phecode
760 Back pain Symptoms 1.01 0.988 – 1.03 0.45 16037 30719 all phecode
761 Cervicalgia Symptoms 0.988 0.963 – 1.01 0.37 6528 39755 all phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 1.02 0.985 – 1.06 0.284 3657 32599 all phecode
764 Sciatica Symptoms 1.04 1.01 – 1.08 0.0251 3542 32015 all phecode
765 Cervical radiculitis Symptoms 1.01 0.963 – 1.06 0.67 1799 17851 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1 0.975 – 1.03 0.767 5124 37132 all phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 0.967 0.82 – 1.16 0.704 117 1168 all phecode
769 Nonallopathic lesions NEC Symptoms 0.966 0.912 – 1.02 0.243 1131 11220 all phecode
770 Myalgia and myositis unspecified Symptoms 1.01 0.979 – 1.04 0.624 5533 34303 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.99 0.96 – 1.02 0.5 4799 35575 all phecode
771.1 Swelling of limb Symptoms 0.993 0.966 – 1.02 0.636 5743 35539 all phecode
771.2 Cramp of limb Symptoms 0.994 0.934 – 1.06 0.842 1079 10568 all phecode
772 Symptoms of the muscles Symptoms 0.993 0.949 – 1.04 0.753 2042 20221 all phecode
772.1 Muscular wasting and disuse atrophy Symptoms 1.05 0.949 – 1.17 0.353 422 4199 all phecode
772.2 Spasm of muscle Symptoms 1.03 0.99 – 1.08 0.13 2299 22726 all phecode
772.3 Muscle weakness Symptoms 0.981 0.945 – 1.02 0.321 2949 28064 all phecode
772.4 Rhabdomyolysis Symptoms 0.939 0.81 – 1.1 0.42 159 1572 all phecode
772.6 Facial weakness Symptoms 0.917 0.84 – 1 0.0546 478 4742 all phecode
780 Hypothermia/Chills Symptoms 0.922 0.84 – 1.02 0.0944 453 4514 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.02 0.976 – 1.06 0.453 2822 26225 all phecode
781.1 Loss of height Symptoms 0.904 0.766 – 1.08 0.248 130 1269 all phecode
781.2 Abnormal posture Symptoms 0.803 0.624 – 1.05 0.0962 57 567 all phecode
782.3 Edema Symptoms 1.03 1 – 1.06 0.0453 5874 36788 all phecode
782.6 Pallor and flushing Symptoms 0.988 0.925 – 1.06 0.719 927 9252 all phecode
783 Fever of unknown origin Symptoms 0.99 0.963 – 1.02 0.472 5733 40720 all phecode
783.1 Postprocedural fever Symptoms 0.944 0.846 – 1.06 0.316 300 2992 all phecode
785 Abdominal pain Symptoms 0.996 0.977 – 1.02 0.706 16458 30297 all phecode
788 Syncope and collapse Symptoms 1.01 0.978 – 1.05 0.514 3851 35832 all phecode
789 Nausea and vomiting Symptoms 0.994 0.972 – 1.02 0.583 10568 36098 all phecode
789.1 Persistent vomiting Symptoms 0.984 0.916 – 1.06 0.664 798 7924 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.03 0.983 – 1.07 0.247 2363 22690 all phecode
790.1 Elevated sedimentation rate Symptoms 1.01 0.881 – 1.16 0.927 236 2322 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.02 0.993 – 1.04 0.158 7539 37788 all phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 0.994 0.885 – 1.12 0.922 309 3075 all phecode
790.9 Abnormal arterial blood gases Symptoms 1.04 0.884 – 1.24 0.654 155 1521 all phecode
791 Gangrene Symptoms 1.06 0.942 – 1.2 0.34 313 3115 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 1.01 0.971 – 1.05 0.602 2820 14872 all phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 1.01 0.951 – 1.08 0.749 1100 9861 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.01 0.924 – 1.11 0.81 515 5133 all phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 1.01 0.967 – 1.06 0.648 2182 20242 all phecode
795.8 Abnormal tumor markers Symptoms 0.98 0.934 – 1.03 0.434 1745 15551 all phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 1.04 0.797 – 1.41 0.776 61 605 all phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 1.06 0.922 – 1.24 0.415 201 2000 all phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.982 0.936 – 1.03 0.46 2125 9930 all phecode
797 Shock Symptoms 0.991 0.913 – 1.08 0.832 605 6050 all phecode
797.1 Cardiogenic shock Symptoms 1.01 0.884 – 1.17 0.845 242 2420 all phecode
798 Malaise and fatigue Symptoms 0.993 0.973 – 1.01 0.547 11539 35196 all phecode
798.1 Chronic fatigue syndrome Symptoms 0.983 0.938 – 1.03 0.494 1823 17795 all phecode
800 Fracture of lower limb Injuries & Poisonings 0.983 0.943 – 1.03 0.424 2344 22951 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.974 0.888 – 1.07 0.58 512 4961 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.947 0.874 – 1.03 0.191 670 6582 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.936 0.877 – 0.999 0.0448 898 8966 all phecode
800.4 Fracture of patella Injuries & Poisonings 0.907 0.817 – 1.01 0.0712 346 3456 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.993 0.952 – 1.04 0.745 2358 22645 all phecode
801.1 Fracture of foot Injuries & Poisonings 0.983 0.926 – 1.05 0.587 1120 11178 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.975 0.883 – 1.08 0.621 380 3765 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.985 0.942 – 1.03 0.519 2051 20360 all phecode
803.1 Fracture of humerus Injuries & Poisonings 0.994 0.923 – 1.07 0.875 734 7322 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.973 0.916 – 1.03 0.377 1112 11075 all phecode
803.21 Colles' fracture Injuries & Poisonings 0.979 0.873 – 1.1 0.72 291 2904 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.97 0.889 – 1.06 0.495 514 5140 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.981 0.934 – 1.03 0.461 1628 16042 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.926 0.878 – 0.979 0.00567 1336 13242 all phecode
807 Fracture of ribs Injuries & Poisonings 0.974 0.903 – 1.05 0.499 683 6815 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.989 0.952 – 1.03 0.558 2941 28633 all phecode
816 Cerebral laceration and contusion Injuries & Poisonings 1.02 0.764 – 1.39 0.909 54 531 all phecode
817 Concussion Injuries & Poisonings 0.961 0.905 – 1.02 0.2 1018 10149 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.02 0.908 – 1.15 0.739 311 3104 all phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.864 0.703 – 1.08 0.176 90 895 all phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.14 0.914 – 1.46 0.251 97 970 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.978 0.938 – 1.02 0.304 2287 22671 all phecode
830 Dislocation Injuries & Poisonings 1.01 0.974 – 1.04 0.695 3862 34720 all phecode
835 Internal derangement of knee Injuries & Poisonings 1.04 0.991 – 1.08 0.12 2231 21628 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1 0.916 – 1.1 0.983 496 4954 all phecode
840 Sprains and strains Injuries & Poisonings 1.01 0.984 – 1.03 0.485 7838 37998 all phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 1 0.919 – 1.1 0.966 537 5356 all phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 1 0.952 – 1.05 0.959 1640 16263 all phecode
840.3 Joint/ligament sprain Injuries & Poisonings 1.03 0.988 – 1.07 0.181 2875 24879 all phecode
841 Sprains and strains of back and neck Injuries & Poisonings 1.03 0.978 – 1.09 0.272 1583 15592 all phecode
842 Other sprains and strains Injuries & Poisonings 1.02 0.97 – 1.08 0.402 1407 13924 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.988 0.945 – 1.03 0.584 2072 20649 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.991 0.955 – 1.03 0.654 2982 27545 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.07 0.969 – 1.18 0.193 460 4600 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.02 0.97 – 1.06 0.514 1985 19675 all phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 0.916 0.814 – 1.04 0.153 264 2640 all phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.01 0.894 – 1.15 0.868 293 2929 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.03 0.977 – 1.1 0.25 1310 13087 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.01 0.964 – 1.05 0.765 2213 21944 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 0.995 0.951 – 1.04 0.815 2110 21070 all phecode
860 Bone marrow or stem cell transplant Neoplasms 1 0.845 – 1.2 0.966 166 1660 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.02 0.983 – 1.05 0.361 4117 36734 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.12 0.967 – 1.32 0.136 204 2026 all phecode
870.2 Open wound of ear Injuries & Poisonings 1.05 0.885 – 1.27 0.571 144 1437 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.02 0.96 – 1.08 0.593 1346 13301 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.901 0.788 – 1.04 0.133 207 2057 all phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 0.896 0.8 – 1.01 0.062 275 2724 all phecode
870.6 Open wound of neck Injuries & Poisonings 0.927 0.813 – 1.07 0.276 214 2128 all phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.42 1.17 – 1.74 0.000546 144 1440 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.01 0.977 – 1.05 0.525 3530 32903 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.972 0.894 – 1.06 0.513 572 5701 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.998 0.934 – 1.07 0.954 984 9772 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.01 0.925 – 1.11 0.791 490 4843 all phecode
871.4 Open wound of toe(s) Injuries & Poisonings 0.939 0.84 – 1.06 0.281 295 2921 all phecode
872 Traumatic amputation Injuries & Poisonings 1.04 0.949 – 1.14 0.433 551 5477 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.02 0.878 – 1.2 0.793 170 1697 all phecode
875 Non-healing surgical wound Injuries & Poisonings 1.02 0.931 – 1.11 0.713 572 5720 all phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.04 0.969 – 1.13 0.261 802 8003 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1 0.942 – 1.07 0.89 1010 10096 all phecode
910 Superficial injury, infected Injuries & Poisonings 1.02 0.846 – 1.25 0.838 119 1161 all phecode
911 Blister Injuries & Poisonings 1.04 0.926 – 1.19 0.482 302 2996 all phecode
912 Insect bite Injuries & Poisonings 1.05 0.951 – 1.15 0.364 492 4886 all phecode
913 Toxic effect of venom Injuries & Poisonings 1.01 0.899 – 1.13 0.906 337 3326 all phecode
916 Contusion Injuries & Poisonings 0.983 0.953 – 1.01 0.282 4296 38033 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.968 0.901 – 1.04 0.381 763 7596 all phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.977 0.906 – 1.06 0.555 714 7072 all phecode
938 Dermatitis due to solar radiation Dermatologic 0.993 0.965 – 1.02 0.653 5567 29098 all phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 1.03 0.895 – 1.2 0.677 217 2164 all phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.992 0.963 – 1.02 0.576 5307 28656 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.02 0.995 – 1.05 0.106 6704 32389 all phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 0.919 0.759 – 1.13 0.403 91 870 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.967 0.842 – 1.12 0.646 188 1880 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.06 0.932 – 1.21 0.39 269 2688 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.965 0.884 – 1.06 0.432 500 4940 all phecode
947 Urticaria Dermatologic 1 0.947 – 1.07 0.903 1177 11454 all phecode
949 Allergies, other Injuries & Poisonings 1.01 0.984 – 1.04 0.484 7251 32350 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.07 0.973 – 1.18 0.169 494 4940 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.17 0.969 – 1.43 0.112 136 1352 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.01 0.956 – 1.07 0.67 1217 12158 all phecode
958.1 Postoperative shock Injuries & Poisonings 0.935 0.812 – 1.09 0.357 169 1688 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.922 0.768 – 1.12 0.39 114 1140 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.02 0.977 – 1.06 0.401 2479 22087 all phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 1.13 1.01 – 1.29 0.0416 342 3403 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.01 0.956 – 1.06 0.833 1636 16005 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.06 0.966 – 1.16 0.237 528 5234 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.02 0.956 – 1.08 0.597 1065 10347 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 0.967 0.901 – 1.04 0.35 803 7976 all phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 0.958 0.866 – 1.06 0.409 379 3782 all phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 0.905 0.715 – 1.17 0.419 62 612 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 0.975 0.891 – 1.07 0.597 478 4773 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.03 0.988 – 1.07 0.173 2533 24531 all phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.03 0.989 – 1.08 0.145 2469 24057 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.97 0.901 – 1.05 0.433 743 7337 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.966 0.897 – 1.04 0.363 712 7027 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.934 0.875 – 0.999 0.0446 864 8601 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.936 0.889 – 0.986 0.0123 1469 14402 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.967 0.81 – 1.17 0.712 119 1182 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.06 0.869 – 1.31 0.577 103 1006 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.997 0.941 – 1.06 0.92 1254 12464 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 0.966 0.862 – 1.09 0.561 281 2797 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.893 0.726 – 1.12 0.303 67 643 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.938 0.836 – 1.06 0.278 288 2858 all phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 0.816 0.669 – 1.01 0.0514 80 776 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1 0.834 – 1.23 0.962 104 1034 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.776 0.654 – 0.929 0.00431 113 1130 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.16 0.915 – 1.52 0.229 81 810 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.827 0.674 – 1.03 0.0734 71 703 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.975 0.93 – 1.02 0.316 1763 16599 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.01 0.977 – 1.05 0.52 3448 30885 all phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 0.942 0.893 – 0.995 0.029 1391 13877 all phecode
985 Toxic effect of other metals Injuries & Poisonings 1.06 0.803 – 1.46 0.67 57 564 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.2 0.98 – 1.49 0.0832 129 1275 all phecode
990 Effects radiation NOS Injuries & Poisonings 0.978 0.947 – 1.01 0.198 3927 31223 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1 0.96 – 1.05 0.909 2192 21710 all phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 0.958 0.853 – 1.08 0.484 291 2910 all phecode
994.2 Sepsis Injuries & Poisonings 1 0.957 – 1.05 0.953 2086 20666 all phecode
994.21 Septic shock Injuries & Poisonings 0.995 0.917 – 1.08 0.898 627 6260 all phecode
008 Intestinal infection Infectious Diseases 1.02 0.953 – 1.08 0.635 1196 4423 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1 0.918 – 1.1 0.921 604 2058 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.02 0.918 – 1.13 0.747 471 1617 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.11 0.982 – 1.26 0.0945 320 1240 exclusion phecode
010 Tuberculosis Infectious Diseases 0.918 0.739 – 1.14 0.442 71 333 exclusion phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.738 0.524 – 1.04 0.0835 39 119 exclusion phecode
038 Septicemia Infectious Diseases 1.07 0.999 – 1.15 0.0535 1044 3452 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.15 0.987 – 1.34 0.0719 278 838 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.09 0.865 – 1.36 0.477 102 331 exclusion phecode
038.3 Bacteremia Infectious Diseases 1.09 0.99 – 1.21 0.0781 555 1690 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.01 0.957 – 1.06 0.743 1870 5160 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.05 0.954 – 1.15 0.322 549 2320 exclusion phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.01 0.897 – 1.14 0.846 328 1245 exclusion phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.08 0.924 – 1.26 0.338 251 1087 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 0.988 0.901 – 1.08 0.796 569 2321 exclusion phecode
041.21 Rheumatic fever / chorea Infectious Diseases 0.678 0.512 – 0.899 0.00693 56 380 exclusion phecode
041.4 E. coli Infectious Diseases 1.01 0.913 – 1.12 0.839 508 1769 exclusion phecode
041.8 H. pylori Infectious Diseases 0.904 0.734 – 1.11 0.342 107 406 exclusion phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.11 0.929 – 1.33 0.248 176 525 exclusion phecode
053 Herpes zoster Infectious Diseases 0.988 0.903 – 1.08 0.794 610 1995 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.06 0.839 – 1.33 0.639 98 293 exclusion phecode
054 Herpes simplex Infectious Diseases 1.06 0.961 – 1.16 0.261 548 1879 exclusion phecode
070 Viral hepatitis Infectious Diseases 0.986 0.859 – 1.13 0.846 232 969 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 0.855 0.581 – 1.26 0.428 26 100 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 1 0.768 – 1.3 0.996 76 232 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.01 0.835 – 1.23 0.905 119 620 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 0.893 0.689 – 1.16 0.393 76 243 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.08 0.954 – 1.22 0.224 327 1380 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.01 0.774 – 1.31 0.969 61 155 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.869 0.635 – 1.19 0.379 51 113 exclusion phecode
078 Viral warts & HPV Infectious Diseases 1.05 0.977 – 1.12 0.193 1119 3378 exclusion phecode
079 Viral infection Infectious Diseases 1.06 1.01 – 1.12 0.0197 2220 3979 exclusion phecode
079.1 Varicella infection Infectious Diseases 1.07 1.01 – 1.15 0.0319 1290 3695 exclusion phecode
079.2 Infectious mononucleosis Infectious Diseases 1.12 0.877 – 1.44 0.356 67 260 exclusion phecode
079.9 Viremia, NOS Infectious Diseases 0.992 0.879 – 1.12 0.9 317 936 exclusion phecode
080 Postoperative infection Infectious Diseases 1.02 0.946 – 1.11 0.576 772 4044 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.01 0.922 – 1.12 0.769 528 2351 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.04 0.924 – 1.18 0.499 323 1541 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.01 0.953 – 1.08 0.652 1374 3909 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 1.01 0.944 – 1.07 0.833 1294 3569 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.998 0.921 – 1.08 0.961 883 2362 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.1 0.979 – 1.24 0.106 392 1187 exclusion phecode
110.13 Dermatophytosis of the body Infectious Diseases 0.988 0.872 – 1.12 0.846 282 1034 exclusion phecode
110.2 Dermatomycoses Infectious Diseases 1.16 0.951 – 1.42 0.141 115 568 exclusion phecode
112 Candidiasis Infectious Diseases 1.02 0.963 – 1.09 0.453 1394 3990 exclusion phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.04 0.918 – 1.19 0.511 295 970 exclusion phecode
117 Mycoses Infectious Diseases 1.11 0.959 – 1.27 0.168 217 799 exclusion phecode
117.1 Histoplasmosis Infectious Diseases 1.12 0.74 – 1.69 0.598 22 110 exclusion phecode
117.4 Aspergillosis Infectious Diseases 0.851 0.621 – 1.17 0.317 57 168 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.898 0.659 – 1.23 0.499 62 248 exclusion phecode
130.1 Lyme disease Infectious Diseases 0.822 0.582 – 1.16 0.266 39 168 exclusion phecode
131 Protozoan infection Infectious Diseases 1.73 0.928 – 3.22 0.0848 25 81 exclusion phecode
132 Infestation (lice, mites) Infectious Diseases 0.819 0.622 – 1.08 0.157 74 274 exclusion phecode
134 Helminthiases Infectious Diseases 0.979 0.63 – 1.52 0.926 27 124 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.15 0.716 – 1.85 0.56 17 83 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.01 0.946 – 1.08 0.768 1096 4941 exclusion phecode
145 Cancer of mouth Neoplasms 0.981 0.841 – 1.14 0.811 166 2403 exclusion phecode
145.1 Cancer of lip Neoplasms 0.976 0.523 – 1.82 0.938 8 118 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.05 0.81 – 1.35 0.729 66 1009 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 1.1 0.83 – 1.46 0.502 49 604 exclusion phecode
145.4 Cancer of the gums Neoplasms 0.799 0.52 – 1.23 0.305 17 281 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 0.679 0.489 – 0.944 0.0211 28 329 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.982 0.836 – 1.15 0.819 154 2154 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 0.933 0.678 – 1.28 0.672 39 532 exclusion phecode
149.2 Cancer of nasopharynx Neoplasms 1.25 0.691 – 2.25 0.464 18 182 exclusion phecode
149.3 Cancer of hypopharynx Neoplasms 0.704 0.45 – 1.1 0.124 14 152 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.1 0.827 – 1.46 0.512 47 625 exclusion phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 1.04 0.822 – 1.32 0.745 80 934 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 0.942 0.634 – 1.4 0.768 25 417 exclusion phecode
150 Cancer of esophagus Neoplasms 0.82 0.645 – 1.04 0.104 79 543 exclusion phecode
151 Cancer of stomach Neoplasms 0.82 0.681 – 0.987 0.0359 111 620 exclusion phecode
153 Colorectal cancer Neoplasms 0.979 0.873 – 1.1 0.713 365 1573 exclusion phecode
153.2 Colon cancer Neoplasms 0.995 0.874 – 1.13 0.946 294 1258 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.1 0.94 – 1.29 0.233 209 867 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.91 0.745 – 1.11 0.358 107 628 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.926 0.716 – 1.2 0.559 79 419 exclusion phecode
157 Pancreatic cancer Neoplasms 1.22 0.971 – 1.52 0.0889 113 655 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.02 0.926 – 1.11 0.74 543 2091 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.994 0.898 – 1.1 0.903 468 2194 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.04 0.789 – 1.36 0.797 56 274 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.937 0.654 – 1.34 0.725 28 208 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.36 0.958 – 1.92 0.0855 48 351 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 0.903 0.601 – 1.36 0.625 35 220 exclusion phecode
165 Cancer within the respiratory system Neoplasms 0.935 0.823 – 1.06 0.306 248 2278 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 0.92 0.798 – 1.06 0.25 208 1849 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 0.953 0.842 – 1.08 0.451 259 2987 exclusion phecode
170.1 Bone cancer Neoplasms 0.93 0.773 – 1.12 0.44 113 1289 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 0.976 0.84 – 1.13 0.747 179 2075 exclusion phecode
172 Skin cancer Neoplasms 0.932 0.879 – 0.989 0.0189 1603 5155 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.954 0.891 – 1.02 0.179 1092 4746 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.98 0.879 – 1.09 0.716 376 3917 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.926 0.872 – 0.985 0.014 1439 4844 exclusion phecode
172.21 Basal cell carcinoma Neoplasms 0.996 0.922 – 1.08 0.922 885 3931 exclusion phecode
172.22 Squamous cell carcinoma Neoplasms 0.972 0.881 – 1.07 0.566 515 2848 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.99 0.884 – 1.11 0.857 370 2115 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.966 0.886 – 1.05 0.428 600 3179 exclusion phecode
174 Breast cancer Neoplasms 0.951 0.871 – 1.04 0.259 616 2508 exclusion phecode
174.1 Breast cancer [female] Neoplasms 0.954 0.869 – 1.05 0.318 566 2383 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.964 0.878 – 1.06 0.45 561 2368 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms – 60 364 exclusion phecode
175 Acquired absence of breast Neoplasms 1.02 0.874 – 1.19 0.812 184 1176 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.07 0.95 – 1.21 0.258 340 1739 exclusion phecode
180.1 Cervical cancer Neoplasms 0.974 0.802 – 1.18 0.791 95 722 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.1 0.957 – 1.26 0.184 274 1281 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 1.03 0.858 – 1.25 0.723 131 1238 exclusion phecode
184 Cancer of other female genital organs Neoplasms 0.996 0.881 – 1.13 0.946 277 2029 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.918 0.773 – 1.09 0.335 114 1014 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.902 0.72 – 1.13 0.366 74 766 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.04 0.889 – 1.22 0.607 164 1096 exclusion phecode
185 Cancer of prostate Neoplasms 0.953 0.847 – 1.07 0.43 446 1241 exclusion phecode
187 Cancer of other male genital organs Neoplasms 1.02 0.795 – 1.31 0.883 65 473 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.29 0.808 – 2.05 0.288 20 174 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.903 0.636 – 1.28 0.567 31 233 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.1 0.555 – 2.2 0.777 14 88 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.07 0.98 – 1.17 0.131 603 3792 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.04 0.908 – 1.19 0.57 233 2361 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.11 0.947 – 1.31 0.196 184 2079 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.38 0.966 – 1.96 0.0765 47 411 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.12 1.01 – 1.25 0.0382 437 2518 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.12 0.999 – 1.25 0.0511 397 2327 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.2 1 – 1.43 0.0505 181 1102 exclusion phecode
190 Cancer of eye Neoplasms 1.06 0.698 – 1.61 0.787 28 239 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.894 0.78 – 1.02 0.107 208 1580 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.92 0.776 – 1.09 0.332 125 1006 exclusion phecode
191.11 Cancer of brain Neoplasms 0.916 0.749 – 1.12 0.397 104 843 exclusion phecode
193 Thyroid cancer Neoplasms 1.15 0.96 – 1.37 0.131 148 1524 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 0.984 0.818 – 1.18 0.86 140 990 exclusion phecode
195 Cancer, suspected or other Neoplasms 0.983 0.933 – 1.04 0.517 3149 3590 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 0.981 0.931 – 1.03 0.475 3101 3586 exclusion phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1.06 0.887 – 1.26 0.531 156 1304 exclusion phecode
196 Radiotherapy Neoplasms 0.995 0.904 – 1.1 0.921 526 2484 exclusion phecode
197 Chemotherapy Neoplasms 1.01 0.945 – 1.08 0.736 1267 3295 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.01 0.937 – 1.09 0.758 961 3244 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.973 0.886 – 1.07 0.562 534 2942 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.07 0.918 – 1.24 0.397 208 1427 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.06 0.896 – 1.24 0.518 187 1222 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.01 0.856 – 1.19 0.911 159 1075 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.976 0.815 – 1.17 0.795 125 898 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 0.941 0.819 – 1.08 0.388 208 1147 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.935 0.739 – 1.18 0.58 78 452 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 0.995 0.932 – 1.06 0.871 1360 3539 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.94 0.888 – 4.22 0.0965 14 121 exclusion phecode
200 Myeloproliferative disease Neoplasms 0.997 0.899 – 1.11 0.957 491 1816 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.39 1.04 – 1.86 0.0268 85 335 exclusion phecode
201 Hodgkin's disease Neoplasms 0.976 0.715 – 1.33 0.879 46 251 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.975 0.881 – 1.08 0.624 428 2586 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.996 0.891 – 1.11 0.942 369 2211 exclusion phecode
202.21 Nodular lymphoma Neoplasms 0.949 0.815 – 1.11 0.501 184 1170 exclusion phecode
202.22 Reticulosarcoma Neoplasms 1.12 0.814 – 1.55 0.481 59 273 exclusion phecode
202.24 Large cell lymphoma Neoplasms 0.937 0.68 – 1.29 0.692 55 256 exclusion phecode
204 Leukemia Neoplasms 0.997 0.875 – 1.14 0.964 278 1182 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1.22 0.929 – 1.6 0.152 77 406 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.26 0.831 – 1.9 0.279 33 106 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.22 0.88 – 1.7 0.23 52 295 exclusion phecode
204.2 Myeloid leukemia Neoplasms 0.971 0.801 – 1.18 0.766 117 466 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 0.929 0.718 – 1.2 0.576 63 267 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.869 0.556 – 1.36 0.536 24 113 exclusion phecode
204.4 Multiple myeloma Neoplasms 0.983 0.797 – 1.21 0.873 107 386 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1.03 0.987 – 1.08 0.155 3579 3746 exclusion phecode
209 Neuroendocrine tumors Neoplasms 1.05 0.828 – 1.32 0.707 65 427 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.05 0.928 – 1.2 0.419 290 2915 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.02 0.975 – 1.07 0.354 2984 3997 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1 0.896 – 1.12 0.981 356 2850 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.18 1.04 – 1.35 0.01 329 1152 exclusion phecode
214 Lipoma Neoplasms 1.01 0.907 – 1.12 0.913 423 2295 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.935 0.82 – 1.07 0.322 256 1424 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1 0.936 – 1.07 0.994 1017 5980 exclusion phecode
216 Benign neoplasm of skin Neoplasms 1.05 1 – 1.1 0.0522 3054 4313 exclusion phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 1.35 0.991 – 1.84 0.0574 63 231 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.03 0.94 – 1.13 0.518 539 2409 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 1.03 0.94 – 1.13 0.504 529 2299 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 1.1 1.03 – 1.19 0.00763 1157 2428 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 1.1 0.997 – 1.22 0.0565 502 2323 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.11 1.02 – 1.2 0.0118 907 2384 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 1 0.861 – 1.17 0.961 190 1262 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.07 0.963 – 1.2 0.2 410 2032 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.943 0.831 – 1.07 0.365 264 1594 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.1 0.98 – 1.24 0.104 378 1020 exclusion phecode
224 Benign neoplasm of eye Neoplasms 1.03 0.891 – 1.19 0.697 245 1268 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.07 0.919 – 1.25 0.374 223 1123 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.982 0.863 – 1.12 0.786 257 1874 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.02 0.865 – 1.2 0.825 173 1449 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.962 0.782 – 1.18 0.716 92 445 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.04 0.91 – 1.18 0.581 254 2291 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.988 0.88 – 1.11 0.844 306 2826 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.06 0.878 – 1.28 0.552 125 866 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.03 0.851 – 1.25 0.757 122 1280 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.785 0.623 – 0.99 0.0407 62 704 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.05 0.963 – 1.14 0.281 685 3606 exclusion phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 1.05 0.949 – 1.17 0.336 446 2390 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.02 0.962 – 1.09 0.465 1226 5853 exclusion phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 1.06 0.975 – 1.14 0.186 735 5453 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.11 0.967 – 1.27 0.142 283 1591 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.03 0.954 – 1.12 0.407 731 3392 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.03 0.943 – 1.12 0.519 607 3059 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.02 0.905 – 1.14 0.796 342 2023 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.04 0.938 – 1.15 0.45 434 2173 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 1.03 0.865 – 1.23 0.725 134 819 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.56 0.987 – 2.46 0.0572 27 190 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.873 0.702 – 1.09 0.222 72 441 exclusion phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.86 0.621 – 1.19 0.364 32 228 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.01 0.952 – 1.06 0.831 1911 4690 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.03 0.927 – 1.15 0.555 381 2633 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.984 0.891 – 1.09 0.747 425 1917 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1 0.946 – 1.06 0.987 1846 4649 exclusion phecode
245 Thyroiditis Endocrine/metabolic 1.06 0.926 – 1.22 0.388 250 1239 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.06 0.908 – 1.23 0.481 201 1028 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.05 0.908 – 1.23 0.487 199 1013 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1 0.945 – 1.07 0.884 1446 4430 exclusion phecode
246.2 Thyroid cyst Endocrine/metabolic 0.917 0.625 – 1.35 0.659 28 163 exclusion phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1.03 0.914 – 1.15 0.656 348 1411 exclusion phecode
249 Secondary diabetes mellitus Endocrine/metabolic 0.971 0.857 – 1.1 0.641 494 911 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.03 0.983 – 1.08 0.205 3856 3548 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.01 0.907 – 1.12 0.897 891 1324 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.01 0.742 – 1.37 0.963 93 105 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.1 0.89 – 1.36 0.381 216 297 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.05 0.874 – 1.27 0.58 296 314 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 0.979 0.806 – 1.19 0.835 273 285 exclusion phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 0.844 0.622 – 1.15 0.278 76 87 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.01 0.953 – 1.07 0.774 2625 3398 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.05 0.798 – 1.37 0.738 119 145 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.01 0.917 – 1.1 0.9 874 1569 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.953 0.855 – 1.06 0.383 702 1125 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 0.938 0.865 – 1.02 0.117 1157 1894 exclusion phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.01 0.881 – 1.16 0.863 430 701 exclusion phecode
250.3 Insulin pump user Endocrine/metabolic 0.968 0.894 – 1.05 0.42 1204 2358 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.06 1 – 1.11 0.0461 2886 3476 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.1 0.998 – 1.2 0.0562 718 1908 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.05 0.996 – 1.11 0.0713 2609 3424 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.04 0.733 – 1.49 0.814 58 114 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.944 0.864 – 1.03 0.2 981 1548 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.994 0.905 – 1.09 0.906 691 1479 exclusion phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 0.868 0.776 – 0.972 0.0142 411 1360 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 0.955 0.847 – 1.08 0.455 491 941 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.02 0.939 – 1.11 0.606 644 3302 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.03 0.942 – 1.13 0.52 594 3075 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.93 0.76 – 1.14 0.476 122 719 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1 0.86 – 1.17 0.963 224 1217 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.956 0.704 – 1.3 0.771 58 373 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.893 0.459 – 1.74 0.739 8 101 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.992 0.737 – 1.34 0.96 57 312 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.22 0.688 – 2.15 0.502 25 121 exclusion phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 1.15 0.819 – 1.6 0.427 48 197 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.937 0.663 – 1.32 0.714 36 154 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.945 0.859 – 1.04 0.25 485 2224 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.909 0.755 – 1.1 0.317 112 575 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.831 0.64 – 1.08 0.164 56 269 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.01 0.72 – 1.41 0.971 37 198 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.918 0.801 – 1.05 0.223 247 914 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.883 0.77 – 1.01 0.0782 237 870 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.996 0.885 – 1.12 0.953 342 1495 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.998 0.864 – 1.15 0.982 228 982 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 0.923 0.82 – 1.04 0.183 344 1168 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.931 0.825 – 1.05 0.247 339 1133 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.782 0.562 – 1.09 0.146 31 142 exclusion phecode
258.1 Postablative ovarian failure Endocrine/metabolic 1.04 0.728 – 1.47 0.847 35 158 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 1.05 0.932 – 1.19 0.417 322 1547 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.01 0.935 – 1.08 0.866 1027 2531 exclusion phecode
260.1 Cachexia Endocrine/metabolic 0.869 0.702 – 1.08 0.198 128 273 exclusion phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 0.938 0.856 – 1.03 0.174 609 1586 exclusion phecode
260.22 Nutritional marasmus Endocrine/metabolic 0.973 0.827 – 1.15 0.743 233 547 exclusion phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.07 0.923 – 1.25 0.354 288 618 exclusion phecode
260.6 Anorexia Endocrine/metabolic 0.926 0.82 – 1.05 0.214 379 856 exclusion phecode
260.7 Polyphagia Endocrine/metabolic 1.19 0.789 – 1.79 0.409 29 66 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.02 0.971 – 1.07 0.427 3346 3124 exclusion phecode
261.1 Vitamin A deficiency Endocrine/metabolic 1.12 0.677 – 1.85 0.663 33 56 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.07 0.961 – 1.18 0.226 584 887 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.02 0.966 – 1.07 0.526 3110 3123 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.1 0.697 – 1.74 0.679 21 47 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.03 0.932 – 1.14 0.553 668 1137 exclusion phecode
263 Other nutritional deficiency Endocrine/metabolic 0.992 0.906 – 1.09 0.862 632 1552 exclusion phecode
264 Lack of normal physiological development Endocrine/metabolic 1.13 0.86 – 1.5 0.372 84 179 exclusion phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.08 0.794 – 1.46 0.636 58 113 exclusion phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 1.45 0.689 – 3.05 0.327 19 53 exclusion phecode
269 Proteinuria Endocrine/metabolic 0.991 0.914 – 1.08 0.835 795 2153 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.03 0.926 – 1.14 0.605 457 1496 exclusion phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 1.08 0.749 – 1.56 0.68 43 245 exclusion phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.993 0.682 – 1.45 0.972 37 194 exclusion phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 0.957 0.687 – 1.33 0.795 42 138 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.03 0.918 – 1.16 0.61 386 1165 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1 0.873 – 1.16 0.952 224 655 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1.08 0.68 – 1.71 0.745 24 105 exclusion phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 0.881 0.549 – 1.41 0.601 27 100 exclusion phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.12 0.918 – 1.36 0.265 151 459 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.11 1.03 – 1.19 0.00581 1008 4492 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.11 1.03 – 1.2 0.00478 981 4394 exclusion phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.29 0.848 – 1.97 0.233 42 160 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.02 0.965 – 1.07 0.534 4585 2809 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.02 0.964 – 1.07 0.549 4573 2808 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.03 0.96 – 1.1 0.425 1764 2330 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.987 0.887 – 1.1 0.814 504 1229 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.03 0.951 – 1.11 0.478 1264 1979 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.962 0.775 – 1.19 0.724 118 344 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.06 0.974 – 1.14 0.188 789 3610 exclusion phecode
274.1 Gout Endocrine/metabolic 1.05 0.971 – 1.14 0.207 743 3482 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.01 0.913 – 1.12 0.832 439 1738 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.08 0.822 – 1.42 0.584 90 352 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.14 0.862 – 1.5 0.364 83 323 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.01 0.959 – 1.07 0.606 1595 5346 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 1.1 0.875 – 1.37 0.425 98 331 exclusion phecode
275.11 Hereditary hemochromatosis Hematopoietic 1.07 0.684 – 1.67 0.768 29 141 exclusion phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 0.689 0.464 – 1.02 0.0656 34 89 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.04 0.941 – 1.16 0.413 483 1728 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.03 0.97 – 1.1 0.302 1215 4626 exclusion phecode
275.51 Hypocalcemia Endocrine/metabolic 1.03 0.912 – 1.17 0.628 317 1340 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.03 0.935 – 1.13 0.564 554 1962 exclusion phecode
275.6 Hypercalcemia Endocrine/metabolic 1.04 0.943 – 1.15 0.438 522 2268 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.04 0.995 – 1.09 0.0828 3182 4208 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.03 0.982 – 1.09 0.2 2331 4000 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.98 0.844 – 1.14 0.795 223 721 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.05 0.974 – 1.14 0.197 932 2738 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.02 0.952 – 1.09 0.565 1185 2980 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.03 0.957 – 1.11 0.412 920 2576 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.02 0.938 – 1.1 0.707 841 2428 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1 0.921 – 1.09 0.951 726 2096 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.04 0.89 – 1.21 0.632 220 607 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.06 0.999 – 1.12 0.0546 1770 3993 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.02 0.928 – 1.12 0.681 597 1617 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 0.84 0.605 – 1.17 0.296 57 148 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 0.981 0.926 – 1.04 0.51 1573 4934 exclusion phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1.06 0.896 – 1.26 0.495 165 680 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.04 0.908 – 1.19 0.563 247 978 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.992 0.878 – 1.12 0.897 335 1389 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.96 0.842 – 1.09 0.541 285 1142 exclusion phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 0.957 0.858 – 1.07 0.422 436 1371 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1 0.958 – 1.05 0.867 4369 3076 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.01 0.966 – 1.06 0.581 3805 3076 exclusion phecode
278.11 Morbid obesity Endocrine/metabolic 0.994 0.941 – 1.05 0.829 2233 3068 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 1.21 0.991 – 1.49 0.0616 152 390 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.03 0.952 – 1.12 0.451 890 2007 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.07 1 – 1.14 0.0443 1267 3496 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.04 0.942 – 1.16 0.407 509 1402 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1 0.836 – 1.21 0.961 171 404 exclusion phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 0.997 0.883 – 1.12 0.956 374 1016 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.03 0.975 – 1.08 0.31 2206 4400 exclusion phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 1.09 0.945 – 1.25 0.246 276 756 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.05 0.989 – 1.1 0.117 2322 2881 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.05 0.99 – 1.11 0.11 2257 2870 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.01 0.935 – 1.1 0.761 952 1700 exclusion phecode
281 Other deficiency anemia Hematopoietic 1 0.872 – 1.15 0.995 357 527 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 0.97 0.792 – 1.19 0.764 173 264 exclusion phecode
281.11 Pernicious anemia Hematopoietic 0.988 0.729 – 1.34 0.936 76 113 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.898 0.712 – 1.13 0.366 121 208 exclusion phecode
281.9 Deficiency anemias Hematopoietic 0.968 0.805 – 1.16 0.729 208 289 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.48 1.13 – 1.93 0.0041 114 302 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 2.17 1.45 – 3.26 0.000172 70 208 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.51 1.08 – 2.11 0.0173 79 176 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.17 0.869 – 1.57 0.302 78 158 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.897 0.585 – 1.37 0.617 34 67 exclusion phecode
284 Aplastic anemia Hematopoietic 1.06 0.921 – 1.23 0.405 341 679 exclusion phecode
284.1 Pancytopenia Hematopoietic 1.07 0.921 – 1.25 0.373 290 612 exclusion phecode
285 Other anemias Hematopoietic 1.02 0.974 – 1.07 0.379 4036 3028 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.04 0.966 – 1.12 0.303 1040 2579 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.02 0.945 – 1.11 0.587 942 1963 exclusion phecode
285.21 Anemia in chronic kidney disease Hematopoietic 0.99 0.883 – 1.11 0.86 460 952 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.11 0.946 – 1.31 0.198 233 644 exclusion phecode
286 Coagulation defects Hematopoietic 0.98 0.923 – 1.04 0.521 1354 4513 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 1.04 0.823 – 1.32 0.738 78 348 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 1.1 0.747 – 1.63 0.621 30 126 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.963 0.686 – 1.35 0.83 37 171 exclusion phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 0.989 0.924 – 1.06 0.747 1152 3491 exclusion phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 1.36 0.792 – 2.34 0.265 17 131 exclusion phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 0.963 0.769 – 1.21 0.741 109 355 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.941 0.692 – 1.28 0.7 66 187 exclusion phecode
286.6 Defibrination syndrome Hematopoietic 0.97 0.903 – 1.04 0.407 878 3499 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.978 0.915 – 1.05 0.516 1058 3980 exclusion phecode
286.8 Hypercoagulable state Hematopoietic 1.08 0.947 – 1.24 0.245 295 1201 exclusion phecode
286.81 Primary hypercoagulable state Hematopoietic 1.08 0.947 – 1.24 0.243 277 1144 exclusion phecode
286.9 Abnormal coagulation profile Hematopoietic 1.01 0.918 – 1.12 0.779 532 1665 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1 0.936 – 1.07 0.951 1132 3800 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.08 0.863 – 1.35 0.511 103 299 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 0.991 0.923 – 1.06 0.795 1019 3507 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 0.945 0.813 – 1.1 0.458 210 821 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.06 0.907 – 1.25 0.446 217 744 exclusion phecode
287.4 Qualitative platelet defects Hematopoietic 0.739 0.514 – 1.06 0.1 41 159 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.03 0.97 – 1.08 0.378 1782 4356 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.02 0.929 – 1.11 0.726 636 2023 exclusion phecode
288.11 Neutropenia Hematopoietic 1.04 0.931 – 1.17 0.467 427 1414 exclusion phecode
288.2 Elevated white blood cell count Hematopoietic 1.02 0.963 – 1.08 0.489 1521 4239 exclusion phecode
288.3 Eosinophilia Hematopoietic 0.81 0.628 – 1.05 0.106 73 199 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.04 0.96 – 1.12 0.339 836 2306 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.975 0.874 – 1.09 0.656 418 1166 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.03 0.964 – 1.1 0.392 1134 4168 exclusion phecode
289.5 Diseases of spleen Hematopoietic 0.954 0.801 – 1.14 0.597 167 504 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.56 1.15 – 2.1 0.0038 91 312 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.23 1.02 – 1.47 0.0294 190 512 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.01 0.915 – 1.11 0.845 642 1464 exclusion phecode
290.1 Dementias Mental Disorders 0.961 0.834 – 1.11 0.584 307 647 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.873 0.65 – 1.17 0.368 92 186 exclusion phecode
290.12 Dementia with cerebral degenerations Mental Disorders 0.928 0.645 – 1.34 0.688 63 100 exclusion phecode
290.13 Senile dementia Mental Disorders 0.986 0.82 – 1.19 0.879 194 412 exclusion phecode
290.16 Vascular dementia Mental Disorders 1.11 0.694 – 1.76 0.671 57 99 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.01 0.885 – 1.15 0.877 346 889 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.967 0.865 – 1.08 0.558 486 1129 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.977 0.91 – 1.05 0.516 1075 3117 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.12 0.84 – 1.5 0.43 54 232 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.861 0.729 – 1.02 0.0812 221 613 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 0.972 0.899 – 1.05 0.484 883 2514 exclusion phecode
292 Neurological disorders Mental Disorders 1 0.953 – 1.06 0.916 2328 4578 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.01 0.922 – 1.1 0.879 665 2357 exclusion phecode
292.11 Aphasia Mental Disorders 0.967 0.838 – 1.12 0.652 235 795 exclusion phecode
292.12 Symbolic dysfunction Mental Disorders 0.989 0.74 – 1.32 0.939 78 209 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.881 0.747 – 1.04 0.129 246 471 exclusion phecode
292.3 Memory loss Mental Disorders 0.991 0.922 – 1.07 0.809 1059 2342 exclusion phecode
292.4 Altered mental status Mental Disorders 1.01 0.94 – 1.08 0.799 1119 2836 exclusion phecode
292.5 Transient alteration of awareness Mental Disorders 0.99 0.842 – 1.16 0.904 199 577 exclusion phecode
292.6 Hallucinations Mental Disorders 1.07 0.857 – 1.33 0.562 133 269 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.01 0.846 – 1.22 0.882 136 667 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.984 0.922 – 1.05 0.633 1080 5905 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1 0.886 – 1.14 0.958 444 663 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.02 0.721 – 1.44 0.919 40 89 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.06 0.676 – 1.66 0.803 49 81 exclusion phecode
295.3 Psychosis Mental Disorders 0.937 0.815 – 1.08 0.361 396 554 exclusion phecode
296 Mood disorders Mental Disorders 1.05 0.99 – 1.12 0.0997 4093 1443 exclusion phecode
296.1 Bipolar Mental Disorders 0.983 0.877 – 1.1 0.764 415 760 exclusion phecode
296.2 Depression Mental Disorders 1.05 0.991 – 1.12 0.0968 4002 1444 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.06 0.993 – 1.12 0.0842 3750 1443 exclusion phecode
297 Suicidal ideation or attempt Mental Disorders 1 0.883 – 1.14 0.969 366 597 exclusion phecode
297.1 Suicidal ideation Mental Disorders 1.02 0.883 – 1.17 0.827 297 491 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.965 0.756 – 1.23 0.777 117 167 exclusion phecode
300 Anxiety disorders Mental Disorders 1.06 1 – 1.13 0.0458 4009 1443 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.07 1.01 – 1.14 0.0299 3790 1442 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 1.08 1.01 – 1.16 0.0267 1877 1428 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.1 0.98 – 1.24 0.106 469 800 exclusion phecode
300.13 Phobia Mental Disorders 1.03 0.908 – 1.16 0.674 358 683 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.03 0.824 – 1.28 0.814 117 207 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.02 0.939 – 1.11 0.635 951 1186 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 0.996 0.835 – 1.19 0.966 205 349 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.16 1 – 1.35 0.0465 299 506 exclusion phecode
301 Personality disorders Mental Disorders 1.11 0.931 – 1.32 0.245 199 328 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.22 0.924 – 1.61 0.161 111 176 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 1.06 0.972 – 1.16 0.179 902 980 exclusion phecode
302.1 Decreased libido Mental Disorders 1.16 0.954 – 1.42 0.134 163 343 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.05 0.987 – 1.13 0.115 2191 1419 exclusion phecode
303.1 Dissociative disorder Mental Disorders 1.06 0.817 – 1.37 0.664 81 131 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 1.06 0.992 – 1.13 0.085 2069 1414 exclusion phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 1.01 0.838 – 1.23 0.883 164 363 exclusion phecode
303.4 Somatoform disorder Mental Disorders 1.04 0.925 – 1.17 0.526 397 761 exclusion phecode
304 Adjustment reaction Mental Disorders 1.11 1.03 – 1.2 0.00974 1374 1432 exclusion phecode
305.2 Eating disorder Mental Disorders 1.07 0.949 – 1.21 0.271 498 600 exclusion phecode
306 Other mental disorder Mental Disorders 1.01 0.917 – 1.12 0.802 655 962 exclusion phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.2 0.975 – 1.48 0.0842 155 239 exclusion phecode
306.9 Tension headache Mental Disorders 0.969 0.846 – 1.11 0.649 301 499 exclusion phecode
312 Conduct disorders Mental Disorders 0.914 0.722 – 1.16 0.453 108 342 exclusion phecode
312.3 Impulse control disorder Mental Disorders 0.884 0.589 – 1.33 0.551 30 108 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 1.01 0.905 – 1.13 0.864 386 1939 exclusion phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1.01 0.901 – 1.14 0.81 323 1739 exclusion phecode
313.2 Tics and stuttering Mental Disorders 0.871 0.588 – 1.29 0.493 26 97 exclusion phecode
313.3 Autism Mental Disorders 0.932 0.515 – 1.68 0.815 17 55 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.08 0.941 – 1.24 0.279 272 1006 exclusion phecode
315.1 Learning disorder Mental Disorders 1.14 0.756 – 1.72 0.531 23 98 exclusion phecode
315.2 Speech and language disorder Mental Disorders 1.32 1.05 – 1.65 0.0175 102 372 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.04 0.975 – 1.11 0.226 1173 4288 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.06 0.89 – 1.26 0.525 187 914 exclusion phecode
317 Alcohol-related disorders Mental Disorders 0.97 0.895 – 1.05 0.453 734 2823 exclusion phecode
317.1 Alcoholism Mental Disorders 0.998 0.914 – 1.09 0.968 592 2371 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 0.935 0.789 – 1.11 0.439 156 522 exclusion phecode
318 Tobacco use disorder Mental Disorders 0.996 0.944 – 1.05 0.872 1964 4619 exclusion phecode
320 Meningitis Neurological 0.959 0.792 – 1.16 0.668 130 551 exclusion phecode
323 Encephalitis Neurological 1.05 0.827 – 1.34 0.674 87 294 exclusion phecode
323.8 Encephalitis, non-infectious Neurological 1 0.78 – 1.29 0.978 76 229 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 0.908 0.732 – 1.13 0.381 85 472 exclusion phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 1.02 0.678 – 1.55 0.91 21 79 exclusion phecode
327 Sleep disorders Neurological 0.973 0.929 – 1.02 0.258 4398 3009 exclusion phecode
327.1 Hypersomnia Neurological 1.02 0.939 – 1.11 0.653 899 1932 exclusion phecode
327.3 Sleep apnea Neurological 0.974 0.926 – 1.02 0.308 3130 2998 exclusion phecode
327.31 Central/nonobstroctive sleep apnea Neurological 0.83 0.697 – 0.988 0.0361 220 525 exclusion phecode
327.32 Obstructive sleep apnea Neurological 0.975 0.925 – 1.03 0.335 2803 2950 exclusion phecode
327.4 Insomnia Neurological 0.966 0.914 – 1.02 0.221 2181 2983 exclusion phecode
327.41 Organic or persistent insomnia Neurological 0.923 0.836 – 1.02 0.11 545 1305 exclusion phecode
327.5 Parasomnia Neurological 0.976 0.847 – 1.12 0.735 320 611 exclusion phecode
327.6 Circadian rhythm sleep disorder Neurological 0.865 0.699 – 1.07 0.183 109 284 exclusion phecode
327.7 Sleep related movement disorders Neurological 0.944 0.867 – 1.03 0.182 733 1865 exclusion phecode
327.71 Restless legs syndrome Neurological 0.945 0.862 – 1.04 0.224 630 1639 exclusion phecode
327.72 Sleep related leg cramps Neurological 0.723 0.469 – 1.11 0.141 39 99 exclusion phecode
331 Other cerebral degenerations Neurological 0.963 0.84 – 1.1 0.586 293 908 exclusion phecode
331.1 Hydrocephalus Neurological 1.06 0.779 – 1.44 0.716 67 314 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 0.988 0.842 – 1.16 0.879 216 557 exclusion phecode
332 Parkinson's disease Neurological 1.1 0.887 – 1.36 0.388 157 523 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1 0.938 – 1.07 0.922 1145 3360 exclusion phecode
333.1 Essential tremor Neurological 0.99 0.86 – 1.14 0.886 310 940 exclusion phecode
333.2 Myoclonus Neurological 1.05 0.822 – 1.33 0.705 83 194 exclusion phecode
333.4 Torsion dystonia Neurological 1.15 0.934 – 1.42 0.186 130 416 exclusion phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 0.959 0.683 – 1.35 0.807 47 122 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 0.935 0.843 – 1.04 0.198 379 1243 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.07 0.656 – 1.76 0.776 34 112 exclusion phecode
334.2 Anterior horn cell disease Neurological 1.24 0.89 – 1.72 0.205 51 129 exclusion phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 1.13 0.728 – 1.76 0.583 34 70 exclusion phecode
335 Multiple sclerosis Neurological 0.939 0.8 – 1.1 0.444 161 449 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.01 0.896 – 1.15 0.829 353 1051 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.05 0.894 – 1.24 0.537 203 547 exclusion phecode
338 Pain Neurological 1.02 0.975 – 1.07 0.35 4835 2615 exclusion phecode
338.1 Acute pain Neurological 1.02 0.973 – 1.08 0.36 3563 2610 exclusion phecode
338.2 Chronic pain Neurological 1.02 0.973 – 1.08 0.365 3407 2606 exclusion phecode
339 Other headache syndromes Neurological 1.03 0.983 – 1.09 0.193 2815 4120 exclusion phecode
340 Migraine Neurological 1.03 0.971 – 1.09 0.333 1968 3573 exclusion phecode
340.1 Migrain with aura Neurological 1.06 0.987 – 1.14 0.108 1148 2798 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.795 0.609 – 1.04 0.0924 72 151 exclusion phecode
342 Hemiplegia Neurological 1.2 1 – 1.43 0.0453 174 585 exclusion phecode
343 Infantile cerebral palsy Neurological 1.13 0.689 – 1.87 0.622 15 90 exclusion phecode
344 Other paralytic syndromes Neurological 0.973 0.841 – 1.13 0.714 273 746 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.02 0.937 – 1.1 0.705 724 2987 exclusion phecode
345.1 Epilepsy Neurological 0.872 0.764 – 0.997 0.0445 230 917 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 0.83 0.653 – 1.06 0.128 57 268 exclusion phecode
345.12 Partial epilepsy Neurological 0.915 0.786 – 1.06 0.249 169 654 exclusion phecode
345.3 Convulsions Neurological 1.02 0.935 – 1.1 0.709 682 2815 exclusion phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.965 0.757 – 1.23 0.774 84 228 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.998 0.911 – 1.09 0.967 582 1856 exclusion phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.993 0.743 – 1.33 0.96 59 141 exclusion phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 0.896 0.658 – 1.22 0.482 52 143 exclusion phecode
347 Cataplexy and narcolepsy Neurological 1.29 0.87 – 1.92 0.204 32 125 exclusion phecode
348 Other conditions of brain Neurological 1.02 0.933 – 1.12 0.64 589 2144 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 0.989 0.851 – 1.15 0.885 193 1005 exclusion phecode
348.4 Cerebral cysts Neurological 0.841 0.66 – 1.07 0.162 66 286 exclusion phecode
348.7 Coma Neurological 0.761 0.592 – 0.977 0.0319 96 277 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.09 0.962 – 1.23 0.181 380 1029 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 0.999 0.919 – 1.09 0.989 690 2770 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.06 0.936 – 1.2 0.357 331 1132 exclusion phecode
350 Abnormal movement Neurological 0.999 0.951 – 1.05 0.958 2618 4702 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.01 0.945 – 1.07 0.853 1380 3818 exclusion phecode
350.2 Abnormality of gait Neurological 0.958 0.904 – 1.02 0.151 1648 3814 exclusion phecode
350.3 Lack of coordination Neurological 1 0.902 – 1.12 0.96 447 1324 exclusion phecode
350.5 Abnormal reflex Neurological 0.97 0.758 – 1.24 0.807 86 258 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.03 0.852 – 1.26 0.729 149 691 exclusion phecode
351 Other peripheral nerve disorders Neurological 1.03 0.979 – 1.08 0.252 2797 3778 exclusion phecode
352 Disorders of other cranial nerves Neurological 0.965 0.869 – 1.07 0.508 411 1930 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.931 0.792 – 1.1 0.39 191 636 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 0.992 0.85 – 1.16 0.92 190 878 exclusion phecode
353 Nerve root and plexus disorders Neurological 1.04 0.973 – 1.1 0.266 1388 3684 exclusion phecode
353.1 Nerve plexus lesions Neurological 1.01 0.816 – 1.24 0.948 114 425 exclusion phecode
353.2 Nerve root lesions Neurological 1.04 0.705 – 1.52 0.86 36 151 exclusion phecode
355 Complex regional/central pain syndrome Neurological 0.872 0.745 – 1.02 0.0899 206 612 exclusion phecode
355.1 Chronic pain syndrome Neurological 1.16 1.02 – 1.31 0.0187 437 953 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.03 0.968 – 1.1 0.324 1263 2782 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.01 0.95 – 1.07 0.807 1662 3881 exclusion phecode
358 Myoneural disorders Neurological 1 0.901 – 1.11 0.999 515 1545 exclusion phecode
358.1 Myasthenia gravis Neurological 0.93 0.654 – 1.32 0.684 42 145 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 1.04 0.939 – 1.16 0.426 465 1528 exclusion phecode
359.1 Muscular dystrophies Neurological 0.814 0.466 – 1.42 0.469 21 81 exclusion phecode
359.2 Myopathy Neurological 1.06 0.948 – 1.17 0.324 452 1474 exclusion phecode
360 Disorders of the globe Sense Organs 0.932 0.69 – 1.26 0.648 52 205 exclusion phecode
360.2 Progressive myopia Sense Organs 0.935 0.608 – 1.44 0.758 27 92 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.932 0.815 – 1.07 0.303 227 1046 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.957 0.761 – 1.2 0.705 90 466 exclusion phecode
362 Other retinal disorders Sense Organs 1.06 0.988 – 1.13 0.107 1351 3153 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.02 0.943 – 1.11 0.578 827 2207 exclusion phecode
362.21 Macular degeneration, dry Sense Organs 1.07 0.897 – 1.27 0.467 203 521 exclusion phecode
362.22 Macular degeneration, wet Sense Organs 0.959 0.718 – 1.28 0.776 66 207 exclusion phecode
362.23 Cystoid macular degeneration of retina Sense Organs 0.963 0.809 – 1.15 0.67 155 549 exclusion phecode
362.26 Macular puckering of retina Sense Organs 0.93 0.831 – 1.04 0.204 370 1289 exclusion phecode
362.27 Drusen (degenerative) of retina Sense Organs 1.18 0.987 – 1.4 0.0704 200 706 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.04 0.949 – 1.13 0.437 715 2007 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.931 0.835 – 1.04 0.195 396 1270 exclusion phecode
362.31 Separation of retinal layers Sense Organs 0.907 0.76 – 1.08 0.28 132 591 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.973 0.845 – 1.12 0.708 288 861 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 1.07 0.887 – 1.3 0.464 149 555 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1 0.791 – 1.27 0.99 70 329 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.12 0.89 – 1.42 0.327 105 369 exclusion phecode
362.9 Retinal edema Sense Organs 1.08 0.892 – 1.3 0.444 143 497 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.932 0.797 – 1.09 0.378 168 725 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.888 0.739 – 1.07 0.202 121 498 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.06 0.943 – 1.2 0.321 384 1613 exclusion phecode
364.1 Corneal opacity Sense Organs 1.06 0.86 – 1.31 0.585 128 602 exclusion phecode
364.2 Corneal edema Sense Organs 1.31 0.81 – 2.13 0.27 37 163 exclusion phecode
364.4 Corneal degenerations Sense Organs 1.04 0.851 – 1.26 0.717 121 620 exclusion phecode
364.41 Keratoconus Sense Organs 1.27 0.718 – 2.26 0.408 20 128 exclusion phecode
364.5 Corneal dystrophy Sense Organs 1.13 0.947 – 1.34 0.179 197 758 exclusion phecode
364.51 Fuchs' dystrophy Sense Organs 0.989 0.774 – 1.26 0.931 98 441 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.966 0.631 – 1.48 0.873 27 141 exclusion phecode
365 Glaucoma Sense Organs 1 0.927 – 1.08 0.962 818 3104 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 0.949 0.83 – 1.09 0.446 242 1036 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.977 0.806 – 1.18 0.81 141 590 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.919 0.713 – 1.19 0.518 91 395 exclusion phecode
366 Cataract Sense Organs 1.01 0.953 – 1.06 0.802 2930 3445 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 0.95 0.756 – 1.19 0.661 89 270 exclusion phecode
366.2 Senile cataract Sense Organs 1.01 0.952 – 1.08 0.7 2160 3024 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.02 0.972 – 1.07 0.418 3056 4395 exclusion phecode
367.1 Myopia Sense Organs 1.02 0.959 – 1.08 0.6 1674 4117 exclusion phecode
367.2 Astigmatism Sense Organs 1.02 0.954 – 1.08 0.629 1405 3945 exclusion phecode
367.8 Hypermetropia Sense Organs 0.986 0.909 – 1.07 0.74 756 2414 exclusion phecode
367.9 Blindness and low vision Sense Organs 0.96 0.866 – 1.07 0.443 455 1606 exclusion phecode
368 Visual disturbances Sense Organs 0.97 0.922 – 1.02 0.245 2078 5230 exclusion phecode
368.1 Amblyopia Sense Organs 0.872 0.751 – 1.01 0.0712 210 921 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.898 0.811 – 0.994 0.0376 404 1588 exclusion phecode
368.3 Anisometropia Sense Organs 0.885 0.715 – 1.1 0.263 84 306 exclusion phecode
368.4 Visual field defects Sense Organs 0.961 0.862 – 1.07 0.475 399 1663 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.993 0.897 – 1.1 0.9 484 1615 exclusion phecode
368.91 Psychophysical visual disturbances Sense Organs 0.929 0.66 – 1.31 0.672 73 159 exclusion phecode
369 Infection of the eye Sense Organs 1.05 0.974 – 1.12 0.217 1054 3660 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.987 0.827 – 1.18 0.883 170 730 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 1.06 0.982 – 1.15 0.133 915 3315 exclusion phecode
370 Keratitis Sense Organs 0.982 0.889 – 1.08 0.723 510 1931 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.908 0.68 – 1.21 0.513 61 316 exclusion phecode
370.2 Superficial keratitis Sense Organs 1.04 0.895 – 1.21 0.607 223 805 exclusion phecode
370.3 Keratoconjunctivitis Sense Organs 1.03 0.899 – 1.19 0.636 262 971 exclusion phecode
370.31 Keratoconjunctivitis sicca Sense Organs 1.03 0.796 – 1.34 0.813 94 262 exclusion phecode
371 Inflammation of the eye Sense Organs 0.999 0.942 – 1.06 0.977 1612 4259 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.96 0.831 – 1.11 0.573 200 789 exclusion phecode
371.2 Conjunctivitis, noninfectious Sense Organs 1.12 0.985 – 1.27 0.0846 319 1315 exclusion phecode
371.21 Allergic conjunctivitis Sense Organs 1.16 1 – 1.34 0.0505 260 1116 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.992 0.93 – 1.06 0.799 1282 3655 exclusion phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 0.854 0.604 – 1.21 0.369 42 170 exclusion phecode
372 Disorders of conjunctiva Sense Organs 0.96 0.859 – 1.07 0.479 388 1539 exclusion phecode
374 Other disorders of eyelids Sense Organs 0.996 0.926 – 1.07 0.903 1012 3304 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.983 0.812 – 1.19 0.862 116 582 exclusion phecode
374.2 Lagophthalmos Sense Organs 0.966 0.74 – 1.26 0.796 59 320 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.875 0.788 – 0.972 0.0129 385 1547 exclusion phecode
374.6 Dermatochalasis Sense Organs 0.964 0.862 – 1.08 0.517 417 1466 exclusion phecode
375 Disorders of lacrimal system Sense Organs 1.04 0.977 – 1.11 0.214 1464 3351 exclusion phecode
375.1 Dry eyes Sense Organs 1.05 0.987 – 1.12 0.125 1645 3448 exclusion phecode
375.2 Epiphora Sense Organs 0.923 0.77 – 1.11 0.383 136 539 exclusion phecode
376 Disorders of the orbit Sense Organs 1.01 0.79 – 1.29 0.935 69 426 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.913 0.811 – 1.03 0.136 298 1144 exclusion phecode
377.1 Optic atrophy Sense Organs 0.909 0.743 – 1.11 0.352 116 380 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.924 0.796 – 1.07 0.294 181 714 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.954 0.86 – 1.06 0.372 405 1595 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.908 0.804 – 1.03 0.121 268 1077 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.16 0.852 – 1.57 0.353 51 218 exclusion phecode
378.5 Paralytic strabismus Sense Organs 0.91 0.741 – 1.12 0.363 98 435 exclusion phecode
379 Other disorders of eye Sense Organs 1.02 0.964 – 1.08 0.473 1850 3744 exclusion phecode
379.1 Scleritis and episcleritis Sense Organs 1.07 0.844 – 1.36 0.578 75 242 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.989 0.925 – 1.06 0.734 1377 2930 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.902 0.674 – 1.21 0.49 50 175 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 0.931 0.746 – 1.16 0.526 105 409 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.914 0.743 – 1.12 0.394 109 418 exclusion phecode
379.51 Pigmentary iris degeneration Sense Organs 1.03 0.58 – 1.83 0.922 20 80 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.993 0.896 – 1.1 0.886 439 1497 exclusion phecode
380 Disorders of external ear Sense Organs 1.04 0.967 – 1.12 0.278 894 3156 exclusion phecode
380.1 Otitis externa Sense Organs 1 0.912 – 1.1 0.987 560 2241 exclusion phecode
380.4 Impacted cerumen Sense Organs 1.06 0.984 – 1.13 0.133 1057 3578 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.03 0.967 – 1.1 0.358 1276 5120 exclusion phecode
381.1 Otitis media Sense Organs 1.06 0.98 – 1.14 0.153 901 4136 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.07 0.986 – 1.16 0.103 764 3539 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 1.04 0.952 – 1.14 0.37 608 2596 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 1.46 0.925 – 2.32 0.103 30 222 exclusion phecode
381.9 Otorrhea Sense Organs 0.975 0.808 – 1.18 0.795 92 519 exclusion phecode
382 Otalgia Sense Organs 1.04 0.956 – 1.13 0.367 694 2738 exclusion phecode
383 Otosclerosis Sense Organs 0.844 0.584 – 1.22 0.366 22 188 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.01 0.832 – 1.22 0.927 129 656 exclusion phecode
384.1 Myringitis Sense Organs 1.23 0.667 – 2.28 0.503 14 71 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.03 0.829 – 1.28 0.782 94 519 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.13 0.856 – 1.5 0.378 64 561 exclusion phecode
385.3 Cholesteatoma Sense Organs 1.05 0.716 – 1.53 0.811 24 346 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.56 0.797 – 3.06 0.194 14 165 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.957 0.881 – 1.04 0.299 693 2465 exclusion phecode
386.1 Meniere's disease Sense Organs 0.879 0.698 – 1.11 0.275 94 444 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.952 0.871 – 1.04 0.269 611 2112 exclusion phecode
386.21 Central origin vertigo Sense Organs 0.966 0.87 – 1.07 0.513 450 1637 exclusion phecode
386.3 Labyrinthitis Sense Organs 0.947 0.861 – 1.04 0.259 527 1976 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.03 0.983 – 1.08 0.208 2616 4671 exclusion phecode
388 Other disorders of ear Sense Organs 1.08 0.943 – 1.23 0.276 315 1326 exclusion phecode
389 Hearing loss Sense Organs 0.98 0.931 – 1.03 0.447 2340 4995 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.992 0.931 – 1.06 0.801 1353 4012 exclusion phecode
389.2 Conductive hearing loss Sense Organs 0.983 0.85 – 1.14 0.821 209 1171 exclusion phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.857 0.677 – 1.09 0.201 80 277 exclusion phecode
389.4 Tinnitus Sense Organs 0.951 0.88 – 1.03 0.213 728 3069 exclusion phecode
389.5 Disorders of acoustic nerve Sense Organs 1.05 0.78 – 1.43 0.73 51 145 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 0.973 0.881 – 1.08 0.594 472 2147 exclusion phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 0.986 0.814 – 1.19 0.882 137 546 exclusion phecode
394.2 Mitral valve disease Circulatory System 0.941 0.797 – 1.11 0.479 158 714 exclusion phecode
394.3 Aortic valve disease Circulatory System 0.985 0.72 – 1.35 0.925 45 298 exclusion phecode
394.4 Acute rheumatic heart disease Circulatory System 0.693 0.378 – 1.27 0.235 20 81 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.06 0.9 – 1.25 0.489 193 846 exclusion phecode
395 Heart valve disorders Circulatory System 0.968 0.906 – 1.04 0.343 1114 4300 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.959 0.879 – 1.05 0.337 617 3202 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.957 0.876 – 1.04 0.325 635 2616 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 0.881 0.759 – 1.02 0.0963 187 726 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.2 0.765 – 1.88 0.428 26 167 exclusion phecode
395.6 Heart valve replaced Circulatory System 0.985 0.874 – 1.11 0.809 305 1653 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.02 0.956 – 1.08 0.57 1273 5131 exclusion phecode
401 Hypertension Circulatory System 0.983 0.932 – 1.04 0.531 4887 2561 exclusion phecode
401.1 Essential hypertension Circulatory System 0.983 0.931 – 1.04 0.521 4845 2560 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 0.969 0.897 – 1.05 0.429 1332 1645 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.06 0.933 – 1.2 0.389 377 752 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.97 0.892 – 1.06 0.481 981 1475 exclusion phecode
401.3 Other hypertensive complications Circulatory System 0.968 0.894 – 1.05 0.416 968 1783 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1 0.952 – 1.06 0.86 2478 4067 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.01 0.899 – 1.13 0.892 425 1186 exclusion phecode
411.2 Myocardial infarction Circulatory System 0.984 0.913 – 1.06 0.668 988 2851 exclusion phecode
411.3 Angina pectoris Circulatory System 1.01 0.931 – 1.09 0.856 909 2432 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.01 0.951 – 1.07 0.819 2164 3685 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.843 0.612 – 1.16 0.296 59 204 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.02 0.955 – 1.08 0.608 1738 3395 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.12 0.936 – 1.33 0.218 199 613 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1 0.932 – 1.08 0.975 1099 3001 exclusion phecode
414.2 ASCVD Circulatory System 1.03 0.899 – 1.18 0.654 291 967 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.01 0.949 – 1.08 0.685 1146 4512 exclusion phecode
415.1 Acute pulmonary heart disease Circulatory System 1.04 0.954 – 1.14 0.361 636 2828 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.04 0.955 – 1.14 0.346 633 2830 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.984 0.907 – 1.07 0.709 698 2781 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.14 0.994 – 1.32 0.0605 301 1149 exclusion phecode
416 Cardiomegaly Circulatory System 1.1 0.995 – 1.23 0.0633 485 1915 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.01 0.961 – 1.06 0.775 4247 3167 exclusion phecode
418.1 Precordial pain Circulatory System 0.959 0.873 – 1.05 0.381 653 1441 exclusion phecode
420 Carditis Circulatory System 1.01 0.921 – 1.1 0.884 583 2460 exclusion phecode
420.1 Myocarditis Circulatory System 0.982 0.621 – 1.55 0.937 33 121 exclusion phecode
420.2 Pericarditis Circulatory System 0.983 0.874 – 1.11 0.78 336 1285 exclusion phecode
420.21 Acute pericarditis Circulatory System 0.89 0.692 – 1.14 0.364 75 249 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.14 0.818 – 1.59 0.436 50 168 exclusion phecode
420.3 Endocarditis Circulatory System 0.999 0.876 – 1.14 0.989 272 1258 exclusion phecode
425 Cardiomyopathy Circulatory System 1.05 0.965 – 1.14 0.26 710 3016 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.05 0.968 – 1.15 0.224 679 2902 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.02 0.773 – 1.33 0.912 71 301 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.36 0.979 – 1.89 0.067 59 275 exclusion phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.13 0.911 – 1.4 0.267 121 454 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 0.936 0.688 – 1.27 0.673 41 152 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.03 0.973 – 1.09 0.313 3799 2141 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 0.98 0.883 – 1.09 0.704 704 958 exclusion phecode
426.21 First degree AV block Circulatory System 1.03 0.916 – 1.17 0.593 489 751 exclusion phecode
426.22 Mobitz II AV block Circulatory System 1.42 0.748 – 2.69 0.285 31 52 exclusion phecode
426.23 Second degree AV block Circulatory System 0.928 0.709 – 1.22 0.59 95 179 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 0.894 0.74 – 1.08 0.241 176 316 exclusion phecode
426.25 Other heart block Circulatory System 0.916 0.675 – 1.24 0.574 98 146 exclusion phecode
426.3 Bundle branch block Circulatory System 1.05 0.955 – 1.15 0.32 762 1165 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.04 0.928 – 1.16 0.51 467 884 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.08 0.94 – 1.24 0.285 339 685 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.915 0.543 – 1.54 0.737 16 62 exclusion phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.03 0.973 – 1.09 0.304 3518 2131 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.02 0.884 – 1.18 0.785 317 608 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.99 0.882 – 1.11 0.859 502 936 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.972 0.849 – 1.11 0.682 346 663 exclusion phecode
426.92 Cardiac defibrillator in situ Circulatory System 0.941 0.811 – 1.09 0.426 282 583 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.01 0.959 – 1.07 0.668 4561 2150 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.07 0.976 – 1.17 0.151 801 1579 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.05 0.945 – 1.17 0.35 532 1238 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.12 0.986 – 1.27 0.0812 406 821 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.06 0.972 – 1.15 0.198 1388 1578 exclusion phecode
427.21 Atrial fibrillation Circulatory System 1.07 0.984 – 1.16 0.115 1368 1556 exclusion phecode
427.22 Atrial flutter Circulatory System 1.06 0.942 – 1.18 0.348 528 906 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.986 0.928 – 1.05 0.636 2684 2137 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.13 0.935 – 1.36 0.209 190 459 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.16 0.839 – 1.61 0.362 75 189 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.12 0.899 – 1.39 0.316 152 364 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.03 0.962 – 1.1 0.409 2040 2136 exclusion phecode
427.6 Premature beats Circulatory System 1.07 0.97 – 1.17 0.185 826 1432 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1.03 0.878 – 1.21 0.725 266 597 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.01 0.944 – 1.07 0.859 1803 2141 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.991 0.866 – 1.13 0.899 341 639 exclusion phecode
427.9 Palpitations Circulatory System 1.04 0.968 – 1.11 0.305 1606 2103 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.04 0.969 – 1.11 0.291 1413 2482 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.03 0.956 – 1.1 0.462 1260 2348 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.06 0.986 – 1.14 0.113 1217 2257 exclusion phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.05 0.957 – 1.16 0.282 649 1450 exclusion phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.04 0.944 – 1.14 0.452 710 1401 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.02 0.972 – 1.07 0.437 3915 3306 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.06 0.944 – 1.2 0.312 373 1183 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.04 0.978 – 1.1 0.233 2367 3095 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.01 0.959 – 1.06 0.75 3101 3305 exclusion phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.02 0.875 – 1.2 0.765 196 720 exclusion phecode
430 Intracranial hemorrhage Circulatory System 0.981 0.856 – 1.12 0.783 254 1186 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.955 0.726 – 1.26 0.743 74 383 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1 0.815 – 1.23 0.997 118 568 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.1 0.86 – 1.4 0.458 91 397 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.02 0.961 – 1.08 0.532 1607 4785 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.997 0.916 – 1.09 0.947 689 2510 exclusion phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.05 0.835 – 1.33 0.662 105 396 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.22 0.785 – 1.91 0.374 41 112 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.01 0.935 – 1.1 0.739 728 3294 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.02 0.937 – 1.1 0.685 707 3204 exclusion phecode
433.3 Cerebral ischemia Circulatory System 0.985 0.916 – 1.06 0.691 904 3424 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 0.978 0.904 – 1.06 0.571 776 3132 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.05 0.833 – 1.33 0.666 85 767 exclusion phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.01 0.869 – 1.18 0.889 234 745 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.932 0.822 – 1.06 0.27 288 997 exclusion phecode
440 Atherosclerosis Circulatory System 1.03 0.955 – 1.11 0.44 947 2590 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.01 0.808 – 1.27 0.914 81 317 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.983 0.899 – 1.07 0.699 647 1831 exclusion phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 0.886 0.737 – 1.07 0.201 126 373 exclusion phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 0.953 0.857 – 1.06 0.371 470 1371 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.08 0.942 – 1.24 0.262 296 1101 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 0.957 0.821 – 1.12 0.576 221 765 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.846 0.673 – 1.06 0.149 111 361 exclusion phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 0.977 0.753 – 1.27 0.861 66 245 exclusion phecode
442 Other aneurysm Circulatory System 0.976 0.899 – 1.06 0.57 742 2759 exclusion phecode
442.1 Aortic aneurysm Circulatory System 0.97 0.885 – 1.06 0.51 574 2094 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.972 0.865 – 1.09 0.627 339 1353 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.03 0.748 – 1.42 0.86 50 253 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.14 0.826 – 1.57 0.428 50 209 exclusion phecode
442.4 Arterial dissection Circulatory System 1.22 0.863 – 1.73 0.26 53 243 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.29 1.02 – 1.63 0.0305 115 535 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.02 0.948 – 1.09 0.66 1157 3330 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.08 0.94 – 1.24 0.274 302 1067 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.855 0.703 – 1.04 0.119 110 355 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.01 0.935 – 1.09 0.815 947 2972 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1 0.923 – 1.08 0.99 866 2533 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 0.99 0.862 – 1.14 0.887 290 1116 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.888 0.704 – 1.12 0.315 108 440 exclusion phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 0.808 0.568 – 1.15 0.237 45 191 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.04 0.883 – 1.22 0.646 214 626 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 0.827 0.605 – 1.13 0.235 44 146 exclusion phecode
446.5 Giant cell arteritis Circulatory System 0.884 0.58 – 1.35 0.569 40 108 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.02 0.834 – 1.25 0.831 154 396 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 0.976 0.906 – 1.05 0.521 900 2956 exclusion phecode
447.1 Stricture of artery Circulatory System 0.922 0.778 – 1.09 0.352 174 672 exclusion phecode
447.7 Aortic ectasia Circulatory System 0.986 0.859 – 1.13 0.836 240 1005 exclusion phecode
448 Disease of capillaries Circulatory System 1.01 0.903 – 1.12 0.909 359 1759 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.02 0.934 – 1.12 0.611 551 3668 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.08 0.927 – 1.25 0.33 269 832 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.2 0.907 – 1.59 0.201 102 290 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 0.997 0.935 – 1.06 0.925 1439 3142 exclusion phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 0.985 0.787 – 1.23 0.895 130 305 exclusion phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 0.993 0.922 – 1.07 0.842 966 2874 exclusion phecode
452.8 Postphlebitic syndrome Circulatory System 1.24 0.872 – 1.75 0.233 54 143 exclusion phecode
453 Chronic venous hypertension Circulatory System 0.791 0.621 – 1.01 0.0571 70 273 exclusion phecode
454 Varicose veins Circulatory System 0.989 0.915 – 1.07 0.79 899 2707 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 0.995 0.917 – 1.08 0.904 834 2448 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.971 0.879 – 1.07 0.559 563 1774 exclusion phecode
455 Hemorrhoids Circulatory System 1.01 0.954 – 1.07 0.728 2061 3199 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.01 0.946 – 1.09 0.686 1204 2800 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.991 0.903 – 1.09 0.844 664 1692 exclusion phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.05 0.848 – 1.31 0.64 123 357 exclusion phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 0.971 0.882 – 1.07 0.54 614 1628 exclusion phecode
458 Hypotension Circulatory System 0.989 0.935 – 1.05 0.689 1851 3954 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 0.916 0.838 – 1 0.0543 651 1664 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 0.988 0.882 – 1.11 0.837 391 1377 exclusion phecode
458.9 Hypotension NOS Circulatory System 0.976 0.922 – 1.03 0.41 1703 3841 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.01 0.957 – 1.06 0.746 2304 4179 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 0.982 0.868 – 1.11 0.78 320 1051 exclusion phecode
459.7 Blood vessel replaced Circulatory System 0.96 0.855 – 1.08 0.495 343 1550 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1 0.949 – 1.06 0.888 2017 4084 exclusion phecode
464 Acute sinusitis Respiratory 1.02 0.958 – 1.08 0.609 1707 3524 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.05 0.997 – 1.1 0.0633 3210 3882 exclusion phecode
465.2 Acute pharyngitis Respiratory 1.08 1.02 – 1.15 0.0098 1742 3446 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.02 0.837 – 1.23 0.873 154 568 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.942 0.853 – 1.04 0.236 421 1767 exclusion phecode
471 Nasal polyps Respiratory 1.02 0.831 – 1.24 0.881 122 683 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.949 0.872 – 1.03 0.224 667 1905 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1 0.927 – 1.08 0.964 831 2715 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.35 0.816 – 2.22 0.244 21 108 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.09 0.911 – 1.31 0.34 149 689 exclusion phecode
473.4 Voice disturbance Respiratory 1.01 0.93 – 1.1 0.772 671 2391 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1.14 0.965 – 1.35 0.122 185 745 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.24 0.914 – 1.68 0.168 63 267 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.11 0.924 – 1.34 0.262 140 590 exclusion phecode
475 Chronic sinusitis Respiratory 1 0.94 – 1.07 0.948 1347 2906 exclusion phecode
475.9 Postnasal drip Respiratory 0.974 0.868 – 1.09 0.661 333 1065 exclusion phecode
476 Allergic rhinitis Respiratory 1.05 0.995 – 1.1 0.0772 3241 2928 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.01 0.899 – 1.13 0.911 406 1221 exclusion phecode
478 Throat pain Respiratory 0.984 0.819 – 1.18 0.861 144 426 exclusion phecode
479 Other upper respiratory disease Respiratory 0.987 0.931 – 1.05 0.657 1732 2922 exclusion phecode
480 Pneumonia Respiratory 0.97 0.921 – 1.02 0.249 2111 4309 exclusion phecode
480.1 Bacterial pneumonia Respiratory 0.984 0.887 – 1.09 0.753 488 1407 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.08 0.938 – 1.25 0.279 260 672 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 0.899 0.674 – 1.2 0.47 53 160 exclusion phecode
480.13 MRSA pneumonia Respiratory 0.851 0.582 – 1.25 0.408 52 126 exclusion phecode
480.2 Viral pneumonia Respiratory 1.1 0.838 – 1.44 0.499 93 276 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.962 0.717 – 1.29 0.793 81 188 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.799 0.578 – 1.11 0.176 42 180 exclusion phecode
481 Influenza Respiratory 1 0.909 – 1.11 0.923 546 1738 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.996 0.935 – 1.06 0.898 1376 3682 exclusion phecode
495 Asthma Respiratory 1 0.953 – 1.06 0.861 2051 4313 exclusion phecode
495.1 Chronic obstructive asthma Respiratory 0.904 0.775 – 1.06 0.201 168 614 exclusion phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 0.942 0.689 – 1.29 0.707 47 146 exclusion phecode
495.2 Asthma with exacerbation Respiratory 0.995 0.908 – 1.09 0.913 589 2154 exclusion phecode
496 Chronic airway obstruction Respiratory 0.964 0.907 – 1.02 0.241 1366 3870 exclusion phecode
496.1 Emphysema Respiratory 0.997 0.909 – 1.09 0.941 561 2743 exclusion phecode
496.2 Chronic bronchitis Respiratory 0.969 0.906 – 1.04 0.358 1066 3675 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 0.953 0.889 – 1.02 0.177 964 3529 exclusion phecode
496.3 Bronchiectasis Respiratory 0.825 0.72 – 0.944 0.00523 201 826 exclusion phecode
497 Bronchitis Respiratory 0.989 0.913 – 1.07 0.788 753 2710 exclusion phecode
498 Acute bronchospasm Respiratory 0.997 0.844 – 1.18 0.968 194 703 exclusion phecode
499 Cystic fibrosis Respiratory 0.72 0.529 – 0.98 0.0368 47 261 exclusion phecode
500 Lung disease due to external agents Respiratory 0.925 0.778 – 1.1 0.379 161 725 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.884 0.607 – 1.29 0.521 45 128 exclusion phecode
500.2 Pneumoconiosis Respiratory 0.805 0.564 – 1.15 0.233 27 97 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.05 0.914 – 1.22 0.464 271 860 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.97 0.853 – 1.1 0.639 308 1113 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.01 0.888 – 1.14 0.917 335 1255 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.929 0.802 – 1.08 0.331 236 835 exclusion phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 1.02 0.833 – 1.24 0.872 124 411 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 0.992 0.906 – 1.09 0.86 641 2212 exclusion phecode
506 Empyema and pneumothorax Respiratory 0.98 0.904 – 1.06 0.623 740 3311 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.02 0.952 – 1.1 0.55 1024 3545 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.976 0.904 – 1.05 0.536 836 3105 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.01 0.945 – 1.08 0.801 1279 3939 exclusion phecode
509.1 Respiratory failure Respiratory 1.01 0.924 – 1.09 0.893 746 2574 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.03 0.931 – 1.15 0.527 454 1597 exclusion phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.04 0.936 – 1.15 0.473 483 2188 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.975 0.889 – 1.07 0.593 575 2353 exclusion phecode
510 Other diseases of lung Respiratory 1 0.949 – 1.05 0.989 1962 4990 exclusion phecode
510.2 Lung transplant Respiratory 1.12 0.841 – 1.49 0.437 67 202 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.04 0.993 – 1.1 0.0918 5390 2061 exclusion phecode
512.1 Wheezing Respiratory 1.04 0.941 – 1.15 0.453 608 1070 exclusion phecode
512.2 Painful respiration Respiratory 0.996 0.918 – 1.08 0.918 937 1640 exclusion phecode
512.3 Abnormal chest sounds Respiratory 1.11 0.902 – 1.36 0.328 154 223 exclusion phecode
512.7 Shortness of breath Respiratory 1.05 0.99 – 1.11 0.108 3559 2057 exclusion phecode
512.8 Cough Respiratory 1.04 0.98 – 1.1 0.203 3477 2060 exclusion phecode
512.9 Other dyspnea Respiratory 1.04 0.985 – 1.1 0.161 3612 2058 exclusion phecode
513 Respiratory abnormalities Respiratory 1.03 0.982 – 1.08 0.225 4009 3441 exclusion phecode
513.3 Hypoventilation Respiratory 1.02 0.903 – 1.15 0.743 384 1025 exclusion phecode
513.31 Apnea Respiratory 1.05 0.874 – 1.27 0.587 183 506 exclusion phecode
513.32 Orthopnea Respiratory 1.11 0.846 – 1.45 0.456 96 233 exclusion phecode
513.4 Hyperventilation Respiratory 0.914 0.772 – 1.08 0.299 196 524 exclusion phecode
513.8 Disorders of diaphragm Respiratory 0.988 0.802 – 1.22 0.907 88 265 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 0.982 0.928 – 1.04 0.537 1578 5137 exclusion phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 0.864 0.698 – 1.07 0.178 102 432 exclusion phecode
514.2 Solitary pulmonary nodule Respiratory 1.04 0.958 – 1.12 0.38 815 4136 exclusion phecode
516 Abnormal sputum Respiratory 0.887 0.782 – 1.01 0.0634 296 1212 exclusion phecode
516.1 Hemoptysis Respiratory 0.831 0.726 – 0.95 0.00689 250 1018 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1 0.95 – 1.05 0.964 2016 5314 exclusion phecode
519.1 Tracheostomy complications Respiratory 1 0.731 – 1.37 0.995 53 284 exclusion phecode
519.2 Respiratory complications Respiratory 1.02 0.839 – 1.23 0.863 126 557 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.03 0.932 – 1.14 0.561 512 2234 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.988 0.932 – 1.05 0.67 1539 4819 exclusion phecode
520 Disorders of tooth development Digestive 1.14 0.823 – 1.56 0.439 53 490 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.868 0.558 – 1.35 0.528 35 266 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 1.64 0.951 – 2.85 0.0753 18 254 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 0.942 0.82 – 1.08 0.399 221 1289 exclusion phecode
521.1 Dental caries Digestive 0.942 0.817 – 1.09 0.415 207 1200 exclusion phecode
521.2 Dental abrasion, erosion and attrition Digestive 0.905 0.511 – 1.6 0.734 13 78 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.02 0.859 – 1.22 0.784 172 750 exclusion phecode
522.5 Periapical abscess Digestive 0.983 0.809 – 1.19 0.866 158 651 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.11 0.944 – 1.3 0.209 222 1038 exclusion phecode
523.1 Gingivitis Digestive 1.03 0.745 – 1.42 0.869 51 199 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.1 0.87 – 1.39 0.431 110 528 exclusion phecode
523.31 Acute periodontitis Digestive 1.1 0.846 – 1.44 0.471 97 462 exclusion phecode
523.32 Chronic periodontitis Digestive 1.06 0.622 – 1.8 0.834 23 175 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.915 0.702 – 1.19 0.515 42 413 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.781 0.567 – 1.07 0.128 24 217 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.985 0.872 – 1.11 0.811 307 1524 exclusion phecode
525.1 Loss of teeth or edentulism Digestive 0.815 0.67 – 0.991 0.0406 90 538 exclusion phecode
526 Diseases of the jaws Digestive 1.02 0.944 – 1.11 0.557 691 3912 exclusion phecode
526.1 Cysts of the jaws Digestive 1.11 0.704 – 1.76 0.644 19 313 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.51 0.977 – 2.35 0.0636 32 263 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.06 0.952 – 1.18 0.291 433 2277 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.01 0.902 – 1.14 0.811 334 1794 exclusion phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 1.11 0.937 – 1.31 0.226 184 1089 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.838 0.664 – 1.06 0.137 49 449 exclusion phecode
526.8 Exostosis of jaw Digestive 1.43 0.756 – 2.72 0.271 14 78 exclusion phecode
526.9 Jaw disease NOS Digestive 0.863 0.704 – 1.06 0.153 94 722 exclusion phecode
527 Diseases of the salivary glands Digestive 1.1 1 – 1.22 0.0474 502 2775 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 0.818 0.557 – 1.2 0.303 19 101 exclusion phecode
527.2 Sialoadenitis Digestive 1.06 0.869 – 1.29 0.568 119 597 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.22 1.05 – 1.41 0.00748 285 1533 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.21 0.919 – 1.61 0.171 67 399 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.02 0.948 – 1.11 0.54 773 4006 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.01 0.873 – 1.17 0.896 234 1015 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.15 0.871 – 1.51 0.33 67 326 exclusion phecode
528.12 Oral aphthae Digestive 0.994 0.786 – 1.26 0.961 91 347 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.809 0.589 – 1.11 0.19 42 330 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 1.21 0.707 – 2.09 0.482 26 181 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.991 0.542 – 1.81 0.978 17 108 exclusion phecode
528.5 Diseases of lips Digestive 1.03 0.877 – 1.22 0.688 172 772 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 0.993 0.662 – 1.49 0.971 27 208 exclusion phecode
528.7 Sialolithiasis Digestive 0.839 0.588 – 1.2 0.331 35 213 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.09 0.946 – 1.27 0.226 228 1038 exclusion phecode
529.1 Glossitis Digestive 1.07 0.813 – 1.42 0.618 60 220 exclusion phecode
529.6 Glossodynia Digestive 1.33 0.98 – 1.81 0.0674 63 271 exclusion phecode
530 Diseases of esophagus Digestive 1.04 0.987 – 1.09 0.153 4551 2565 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.04 0.991 – 1.09 0.113 4431 2565 exclusion phecode
530.11 GERD Digestive 1.04 0.986 – 1.09 0.157 4298 2565 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.09 0.896 – 1.32 0.395 178 380 exclusion phecode
530.13 Barrett's esophagus Digestive 1.07 0.914 – 1.25 0.406 226 793 exclusion phecode
530.14 Reflux esophagitis Digestive 1.06 0.98 – 1.16 0.137 853 1836 exclusion phecode
530.15 Eosinophilic esophagitis Digestive 1.39 0.979 – 1.96 0.0654 64 208 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.07 0.906 – 1.26 0.442 210 659 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1.03 0.907 – 1.17 0.641 309 934 exclusion phecode
530.5 Disorders of esophageal motility Digestive 0.908 0.787 – 1.05 0.185 223 560 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.04 0.673 – 1.6 0.872 23 120 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.08 0.743 – 1.56 0.699 41 77 exclusion phecode
530.9 Heartburn Digestive 1.07 0.971 – 1.18 0.171 580 1538 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.02 0.945 – 1.1 0.595 815 3370 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.972 0.829 – 1.14 0.724 169 636 exclusion phecode
531.2 Gastric ulcer Digestive 0.983 0.889 – 1.09 0.73 467 1975 exclusion phecode
531.3 Duodenal ulcer Digestive 1.09 0.936 – 1.27 0.265 202 749 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 0.978 0.874 – 1.09 0.702 359 1389 exclusion phecode
531.5 Gastrojejunal ulcer Digestive 1.1 0.857 – 1.42 0.448 81 228 exclusion phecode
532 Dysphagia Digestive 1.03 0.965 – 1.09 0.399 1791 2502 exclusion phecode
535 Gastritis and duodenitis Digestive 1.01 0.944 – 1.08 0.776 1146 3622 exclusion phecode
535.1 Acute gastritis Digestive 0.95 0.858 – 1.05 0.324 448 1613 exclusion phecode
535.2 Atrophic gastritis Digestive 1.01 0.839 – 1.22 0.889 179 448 exclusion phecode
535.6 Duodenitis Digestive 1.05 0.879 – 1.26 0.584 154 462 exclusion phecode
535.8 Other specified gastritis Digestive 0.936 0.821 – 1.07 0.325 330 898 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1 0.915 – 1.1 0.928 564 1723 exclusion phecode
536 Disorders of function of stomach Digestive 1.01 0.943 – 1.07 0.855 1221 3639 exclusion phecode
536.3 Gastroparesis Digestive 0.997 0.881 – 1.13 0.964 337 1008 exclusion phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 0.989 0.825 – 1.19 0.907 158 498 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.985 0.914 – 1.06 0.693 927 2822 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.07 1.01 – 1.15 0.0259 1402 3998 exclusion phecode
537.1 Lesions of stomach and duodenum Digestive 1.16 0.892 – 1.5 0.272 84 237 exclusion phecode
539 Bariatric surgery Digestive 0.972 0.898 – 1.05 0.476 852 2374 exclusion phecode
540 Appendiceal conditions Digestive 1.14 0.95 – 1.36 0.16 158 773 exclusion phecode
540.1 Appendicitis Digestive 1.14 0.937 – 1.38 0.194 140 660 exclusion phecode
540.11 Acute appendicitis Digestive 1.12 0.918 – 1.37 0.259 121 551 exclusion phecode
550 Abdominal hernia Digestive 1.02 0.966 – 1.07 0.502 2054 5201 exclusion phecode
550.1 Inguinal hernia Digestive 0.993 0.898 – 1.1 0.893 454 2181 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.04 0.965 – 1.11 0.335 1014 3841 exclusion phecode
550.3 Femoral hernia Digestive 0.967 0.735 – 1.27 0.813 54 179 exclusion phecode
550.4 Umbilical hernia Digestive 1.03 0.926 – 1.15 0.569 393 1760 exclusion phecode
550.5 Ventral hernia Digestive 0.97 0.897 – 1.05 0.441 729 3159 exclusion phecode
550.6 Incisional hernia Digestive 1.02 0.922 – 1.13 0.692 443 1912 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.12 1.01 – 1.24 0.0252 706 1054 exclusion phecode
555.1 Regional enteritis Digestive 1.18 1.04 – 1.34 0.00827 510 594 exclusion phecode
555.2 Ulcerative colitis Digestive 1.2 1.05 – 1.37 0.00687 414 651 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.22 1.03 – 1.45 0.0207 266 365 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1 0.874 – 1.15 0.99 339 522 exclusion phecode
556.1 Ulceration of intestine Digestive 0.999 0.862 – 1.16 0.991 306 455 exclusion phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 0.995 0.779 – 1.27 0.966 122 192 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.01 0.934 – 1.1 0.74 974 1271 exclusion phecode
557.1 Celiac disease Digestive 0.943 0.776 – 1.15 0.553 171 334 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.02 0.958 – 1.1 0.476 1523 1886 exclusion phecode
559 Ileostomy status Digestive 1.16 1.02 – 1.32 0.0218 383 658 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.07 0.99 – 1.15 0.0905 1160 1796 exclusion phecode
560.1 Paralytic ileus Digestive 0.978 0.882 – 1.08 0.675 538 1145 exclusion phecode
560.2 Impaction of intestine Digestive 1.1 0.89 – 1.36 0.374 177 307 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.09 0.869 – 1.37 0.452 120 207 exclusion phecode
560.4 Other intestinal obstruction Digestive 1.12 1.02 – 1.23 0.0144 754 1192 exclusion phecode
561 Symptoms involving digestive system Digestive 0.987 0.914 – 1.07 0.74 1079 1672 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1.04 0.97 – 1.11 0.281 2146 1789 exclusion phecode
562.1 Diverticulosis Digestive 1.04 0.968 – 1.11 0.311 2123 1785 exclusion phecode
562.2 Diverticulitis Digestive 1.07 0.96 – 1.2 0.213 491 1206 exclusion phecode
564 Functional digestive disorders Digestive 1.04 0.981 – 1.09 0.198 3711 2001 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 0.976 0.907 – 1.05 0.512 1250 1652 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.03 0.96 – 1.11 0.38 1105 1859 exclusion phecode
565 Anal and rectal conditions Digestive 1.01 0.945 – 1.08 0.804 1231 3432 exclusion phecode
565.1 Anal and rectal polyp Digestive 0.99 0.894 – 1.1 0.848 479 1592 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.07 0.959 – 1.19 0.236 532 1456 exclusion phecode
568 Other disorders of peritoneum Digestive 1.14 1.03 – 1.26 0.0137 543 1865 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.15 1.02 – 1.29 0.0193 381 1389 exclusion phecode
569 Other disorders of intestine Digestive 1.03 0.978 – 1.08 0.284 2969 3816 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.05 0.854 – 1.28 0.662 127 364 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.05 0.955 – 1.16 0.31 651 1505 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.03 0.966 – 1.09 0.412 1559 3594 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.03 0.964 – 1.09 0.427 1474 3565 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.03 0.917 – 1.17 0.588 325 1215 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 0.904 0.696 – 1.17 0.447 79 216 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.994 0.878 – 1.12 0.925 322 1115 exclusion phecode
571.81 Portal hypertension Digestive 1.04 0.883 – 1.24 0.61 189 670 exclusion phecode
572 Ascites (non malignant) Digestive 1.04 0.955 – 1.12 0.391 781 2594 exclusion phecode
573 Other disorders of liver Digestive 1 0.949 – 1.06 0.916 1836 3723 exclusion phecode
573.1 Chronic passive congestion of liver Digestive 0.973 0.737 – 1.29 0.847 56 147 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.08 0.853 – 1.37 0.523 110 319 exclusion phecode
573.3 Hepatomegaly Digestive 0.966 0.799 – 1.17 0.723 139 568 exclusion phecode
573.4 Acute and subacute necrosis of liver Digestive 1.08 0.867 – 1.33 0.507 119 356 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1.04 0.919 – 1.18 0.541 331 1089 exclusion phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.05 0.974 – 1.12 0.213 1034 2977 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.04 0.976 – 1.11 0.217 1218 3138 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.03 0.972 – 1.09 0.321 1783 3711 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.03 0.96 – 1.1 0.442 1080 4748 exclusion phecode
574.1 Cholelithiasis Digestive 1.03 0.963 – 1.11 0.369 994 4458 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.01 0.811 – 1.25 0.961 133 560 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.999 0.836 – 1.19 0.987 176 840 exclusion phecode
574.2 Calculus of bile duct Digestive 1.05 0.922 – 1.19 0.466 303 1330 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.08 0.942 – 1.23 0.282 312 1294 exclusion phecode
575 Other biliary tract disease Digestive 1 0.927 – 1.08 0.992 814 3429 exclusion phecode
575.1 Cholangitis Digestive 1.09 0.877 – 1.35 0.44 132 518 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.02 0.877 – 1.19 0.802 198 901 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.902 0.69 – 1.18 0.453 59 281 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.03 0.911 – 1.15 0.677 370 1418 exclusion phecode
575.8 Other disorders of biliary tract Digestive 0.933 0.842 – 1.03 0.186 423 1754 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.04 0.796 – 1.36 0.779 92 376 exclusion phecode
577 Diseases of pancreas Digestive 0.978 0.907 – 1.05 0.565 789 3711 exclusion phecode
577.1 Acute pancreatitis Digestive 0.996 0.904 – 1.1 0.942 466 1996 exclusion phecode
577.2 Chronic pancreatitis Digestive 0.987 0.86 – 1.13 0.855 205 880 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.931 0.812 – 1.07 0.31 206 1016 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.956 – 1.07 0.721 1869 4275 exclusion phecode
578.1 Hematemesis Digestive 0.954 0.825 – 1.1 0.518 215 596 exclusion phecode
578.2 Blood in stool Digestive 1 0.937 – 1.07 0.986 1212 3260 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.03 0.951 – 1.11 0.488 896 2659 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.02 0.938 – 1.12 0.605 694 1954 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.02 0.96 – 1.08 0.541 1604 4043 exclusion phecode
579.2 Splenomegaly Digestive 1.01 0.886 – 1.14 0.917 312 871 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.94 0.857 – 1.03 0.188 640 1883 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.07 0.975 – 1.17 0.157 776 1853 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.17 0.958 – 1.42 0.126 182 479 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.13 0.819 – 1.57 0.446 57 179 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.13 0.755 – 1.68 0.56 49 126 exclusion phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.07 0.598 – 1.9 0.827 28 70 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.05 0.845 – 1.3 0.672 139 342 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.24 0.923 – 1.66 0.153 83 236 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.07 0.969 – 1.18 0.18 653 1440 exclusion phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.06 0.944 – 1.2 0.309 458 916 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.05 0.912 – 1.22 0.479 287 826 exclusion phecode
580.4 Renal sclerosis, NOS Genitourinary 0.945 0.77 – 1.16 0.591 112 405 exclusion phecode
585 Renal failure Genitourinary 1.03 0.972 – 1.08 0.355 2404 3768 exclusion phecode
585.1 Acute renal failure Genitourinary 1.05 0.983 – 1.12 0.151 1671 3168 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.02 0.904 – 1.14 0.798 376 1006 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.02 0.961 – 1.08 0.519 1814 3471 exclusion phecode
585.31 Renal dialysis Genitourinary 1.04 0.906 – 1.2 0.57 298 855 exclusion phecode
585.32 End stage renal disease Genitourinary 1.03 0.918 – 1.17 0.575 394 1110 exclusion phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.04 0.967 – 1.12 0.292 1234 2510 exclusion phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 0.97 0.863 – 1.09 0.61 426 1091 exclusion phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.05 0.944 – 1.17 0.353 514 1365 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.03 0.979 – 1.09 0.239 2353 3919 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.991 0.806 – 1.22 0.934 107 418 exclusion phecode
586.11 Small kidney Genitourinary 0.898 0.694 – 1.16 0.413 64 262 exclusion phecode
586.12 Vesicoureteral reflux Genitourinary 1.12 0.743 – 1.68 0.591 39 142 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.07 0.959 – 1.19 0.233 463 1555 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.1 0.796 – 1.51 0.575 59 229 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.12 1 – 1.25 0.0405 473 1988 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.06 0.918 – 1.22 0.442 287 895 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.07 0.957 – 1.2 0.225 438 1131 exclusion phecode
588.1 Renal osteodystrophy Genitourinary 1.06 0.861 – 1.31 0.564 110 316 exclusion phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.06 0.93 – 1.21 0.384 339 896 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.06 0.941 – 1.18 0.354 455 1234 exclusion phecode
590 Pyelonephritis Genitourinary 1.13 1.02 – 1.25 0.0237 558 1659 exclusion phecode
591 Urinary tract infection Genitourinary 1.04 0.989 – 1.09 0.127 3107 3641 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.08 1.01 – 1.16 0.0352 1120 2805 exclusion phecode
592.1 Cystitis Genitourinary 1.09 1.01 – 1.17 0.0278 1076 2715 exclusion phecode
592.11 Acute cystitis Genitourinary 1.07 0.978 – 1.18 0.136 735 1921 exclusion phecode
592.12 Chronic cystitis Genitourinary 1 0.769 – 1.31 0.981 97 294 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.04 0.859 – 1.27 0.662 124 492 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.02 0.764 – 1.35 0.917 67 234 exclusion phecode
593 Hematuria Genitourinary 1.05 0.991 – 1.12 0.0991 1656 3598 exclusion phecode
593.1 Gross hematuria Genitourinary 1.13 1.02 – 1.25 0.021 514 1795 exclusion phecode
593.2 Microscopic hematuria Genitourinary 1.04 0.925 – 1.16 0.538 390 1237 exclusion phecode
594 Urinary calculus Genitourinary 1.04 0.982 – 1.1 0.187 1598 5562 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.04 0.979 – 1.1 0.21 1509 5546 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.51 1.15 – 1.97 0.00275 96 565 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.07 0.956 – 1.19 0.252 419 1975 exclusion phecode
594.8 Renal colic Genitourinary 0.982 0.813 – 1.19 0.853 125 485 exclusion phecode
595 Hydronephrosis Genitourinary 1.09 0.985 – 1.21 0.0954 488 2403 exclusion phecode
596 Other disorders of bladder Genitourinary 1 0.934 – 1.07 0.976 959 4347 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.1 0.873 – 1.39 0.411 92 584 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 0.978 0.894 – 1.07 0.621 592 2712 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.04 0.911 – 1.19 0.569 280 1689 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.12 0.927 – 1.36 0.237 126 858 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.06 0.929 – 1.21 0.394 291 1558 exclusion phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.4 0.956 – 2.05 0.0839 42 315 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.17 0.86 – 1.58 0.321 62 245 exclusion phecode
598.4 Other cells and casts in urine Genitourinary 1.15 0.84 – 1.57 0.386 52 222 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.03 0.985 – 1.08 0.179 3935 3187 exclusion phecode
599.1 Urinary obstruction Genitourinary 1.05 0.902 – 1.23 0.512 235 726 exclusion phecode
599.2 Retention of urine Genitourinary 1.03 0.966 – 1.1 0.369 1448 2980 exclusion phecode
599.3 Dysuria Genitourinary 1.03 0.968 – 1.1 0.343 1529 2998 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.996 0.937 – 1.06 0.894 1709 2942 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.04 0.981 – 1.11 0.179 1769 3089 exclusion phecode
599.6 Oliguria and anuria Genitourinary 0.861 0.747 – 0.994 0.0408 217 621 exclusion phecode
599.7 Urethral discharge Genitourinary 1.09 0.7 – 1.7 0.701 30 133 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.05 0.984 – 1.11 0.146 1634 3040 exclusion phecode
599.9 Other abnormality of urination Genitourinary 1 0.936 – 1.08 0.898 1056 2775 exclusion phecode
600 Hyperplasia of prostate Genitourinary 0.99 0.909 – 1.08 0.827 1085 1397 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 1.04 0.911 – 1.18 0.573 310 1152 exclusion phecode
601.1 Prostatitis Genitourinary 0.919 0.78 – 1.08 0.313 153 588 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.949 0.677 – 1.33 0.762 37 143 exclusion phecode
601.12 Chronic prostatitis Genitourinary 0.67 0.478 – 0.94 0.0203 27 135 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.945 0.779 – 1.15 0.566 115 467 exclusion phecode
601.4 Balanoposthitis Genitourinary 0.968 0.691 – 1.35 0.848 33 124 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.66 1.11 – 2.5 0.0146 51 194 exclusion phecode
602 Other disorders of prostate Genitourinary 0.942 0.77 – 1.15 0.562 104 421 exclusion phecode
602.3 Dysplasia of prostate Genitourinary 1.07 0.71 – 1.6 0.756 23 96 exclusion phecode
603 Other disorders of testis Genitourinary 1.14 0.931 – 1.39 0.209 121 445 exclusion phecode
603.1 Hydrocele Genitourinary 1.25 0.978 – 1.61 0.0746 84 323 exclusion phecode
603.2 Spermatocele Genitourinary 1.33 0.907 – 1.96 0.144 41 148 exclusion phecode
604 Disorders of penis Genitourinary 0.953 0.81 – 1.12 0.566 173 687 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.944 0.631 – 1.41 0.777 37 157 exclusion phecode
604.3 Peyronie's disease Genitourinary 1.19 0.755 – 1.87 0.454 34 236 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 1.04 0.951 – 1.14 0.397 917 1265 exclusion phecode
608 Other disorders of male genital organs Genitourinary 0.985 0.885 – 1.1 0.779 434 1294 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.885 0.712 – 1.1 0.273 84 413 exclusion phecode
609.1 Infertility, male Genitourinary 0.845 0.634 – 1.13 0.249 53 276 exclusion phecode
609.11 Azoospermia and oligospermia Genitourinary 0.684 0.379 – 1.24 0.209 15 78 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.812 0.571 – 1.15 0.247 33 165 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.972 0.898 – 1.05 0.473 978 2058 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.931 0.842 – 1.03 0.165 443 1799 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 0.993 0.663 – 1.49 0.971 22 82 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 1.01 0.927 – 1.11 0.782 744 2045 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.948 0.844 – 1.07 0.374 320 1523 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.988 0.927 – 1.05 0.697 1872 2387 exclusion phecode
611.1 Abnormal mammogram Genitourinary 1 0.937 – 1.08 0.898 1532 2053 exclusion phecode
611.11 Mammographic microcalcification Genitourinary 1.04 0.918 – 1.17 0.565 360 1335 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.97 0.903 – 1.04 0.4 1114 2358 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.01 0.891 – 1.15 0.866 315 1375 exclusion phecode
612.1 Galactorrhea Genitourinary – 53 206 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.02 0.88 – 1.18 0.781 235 1023 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 1.15 0.75 – 1.78 0.514 27 101 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.968 0.905 – 1.03 0.337 1174 3411 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 0.959 0.808 – 1.14 0.631 162 927 exclusion phecode
613.5 Mastodynia Genitourinary 0.973 0.892 – 1.06 0.539 607 2581 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 0.926 0.819 – 1.05 0.225 297 1405 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 0.91 0.801 – 1.03 0.15 257 1422 exclusion phecode
613.9 Breast disorder NOS Genitourinary 1.03 0.92 – 1.14 0.65 403 2291 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.03 0.961 – 1.1 0.412 1202 2854 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.941 0.753 – 1.18 0.597 87 486 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.09 0.907 – 1.31 0.353 156 673 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.48 0.958 – 2.28 0.0772 33 121 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.18 0.854 – 1.62 0.322 58 269 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.24 0.949 – 1.63 0.114 85 330 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.898 0.667 – 1.21 0.476 43 251 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.03 0.957 – 1.1 0.456 1071 2828 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.23 0.952 – 1.58 0.113 83 361 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.02 0.944 – 1.1 0.658 953 2723 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.27 0.846 – 1.91 0.248 47 205 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.02 0.801 – 1.3 0.874 72 348 exclusion phecode
615 Endometriosis Genitourinary 1.01 0.911 – 1.13 0.795 402 2076 exclusion phecode
618 Genital prolapse Genitourinary 0.968 0.884 – 1.06 0.483 567 3125 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 0.917 0.817 – 1.03 0.145 323 2372 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.07 0.883 – 1.3 0.487 141 954 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.01 0.716 – 1.43 0.949 36 550 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.971 0.822 – 1.15 0.724 158 753 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1.07 1 – 1.14 0.04 1577 2719 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.13 0.999 – 1.28 0.0516 347 1642 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 1.15 0.978 – 1.36 0.09 186 844 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.01 0.848 – 1.21 0.892 125 660 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.07 0.982 – 1.16 0.124 762 2656 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.02 0.916 – 1.13 0.747 414 1741 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1.12 0.907 – 1.38 0.292 115 640 exclusion phecode
620.1 Dysplasia of cervix Genitourinary 0.844 0.619 – 1.15 0.286 43 274 exclusion phecode
621 Endometrial hyperplasia Genitourinary 1.25 1.01 – 1.53 0.0383 131 704 exclusion phecode
622 Polyp of female genital organs Genitourinary 1.06 0.952 – 1.19 0.277 441 2384 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 1.02 0.905 – 1.15 0.724 350 1873 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 1.11 0.904 – 1.37 0.313 131 759 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 0.975 0.86 – 1.11 0.7 269 1370 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 1.1 0.98 – 1.23 0.108 404 1584 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 1.27 0.94 – 1.7 0.12 71 305 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 0.721 0.455 – 1.14 0.164 23 102 exclusion phecode
624.9 stress incontinence, female Genitourinary 1.07 0.97 – 1.18 0.178 564 2068 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.09 1.02 – 1.16 0.00945 1723 2233 exclusion phecode
625.1 Dyspareunia Genitourinary 1.06 0.945 – 1.2 0.307 345 1536 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.06 0.986 – 1.14 0.119 1647 1811 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.08 1 – 1.17 0.0396 1319 1658 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 1.1 0.964 – 1.26 0.154 337 878 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 1.09 0.994 – 1.21 0.0675 703 1289 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 1.07 0.97 – 1.19 0.172 628 1327 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 1.2 1.05 – 1.39 0.0098 315 961 exclusion phecode
626.15 Infertility, female, associated with anovulation Genitourinary 1.15 0.921 – 1.43 0.22 112 417 exclusion phecode
626.2 Dysmenorrhea Genitourinary 1.09 0.966 – 1.24 0.156 386 1022 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.996 0.812 – 1.22 0.971 107 363 exclusion phecode
626.8 Infertility, female Genitourinary 1.11 0.953 – 1.3 0.176 214 709 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.04 0.968 – 1.12 0.284 1474 1751 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 1.06 0.938 – 1.19 0.36 418 1306 exclusion phecode
627.2 Symptomatic menopause Genitourinary 1.01 0.933 – 1.09 0.822 1009 1678 exclusion phecode
627.21 Symptomatic artificial menopause Genitourinary 0.925 0.693 – 1.23 0.597 49 177 exclusion phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.887 0.744 – 1.06 0.186 134 504 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.939 0.828 – 1.07 0.329 337 1217 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 1.12 0.893 – 1.41 0.323 132 412 exclusion phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.895 0.715 – 1.12 0.335 87 368 exclusion phecode
628 Ovarian cyst Genitourinary 1.09 0.987 – 1.2 0.0887 623 1549 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.04 0.906 – 1.2 0.567 221 1239 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.23 0.927 – 1.62 0.153 72 424 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.11 0.686 – 1.79 0.671 21 172 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.04 0.862 – 1.25 0.683 120 793 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.09 0.868 – 1.36 0.47 84 563 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.983 0.755 – 1.28 0.898 53 418 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.09 0.953 – 1.26 0.2 272 1194 exclusion phecode
636.1 Threatened premature labor Pregnancy Complications 1.08 0.871 – 1.35 0.468 94 576 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.905 0.732 – 1.12 0.356 83 440 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.19 0.973 – 1.47 0.09 115 642 exclusion phecode
636.8 Cervical incompetence Pregnancy Complications 1.03 0.648 – 1.65 0.893 23 134 exclusion phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 0.731 0.485 – 1.1 0.136 30 129 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.953 0.81 – 1.12 0.557 166 869 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.96 0.779 – 1.18 0.697 94 467 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.997 0.765 – 1.3 0.981 66 382 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.16 0.786 – 1.73 0.448 37 195 exclusion phecode
644 Anemia during pregnancy Pregnancy Complications 1.19 0.891 – 1.6 0.237 57 308 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.01 0.871 – 1.17 0.905 210 924 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.946 0.71 – 1.26 0.705 37 350 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.952 0.737 – 1.23 0.709 56 332 exclusion phecode
647.3 Major puerperal infection Pregnancy Complications 1.01 0.589 – 1.74 0.964 10 88 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.11 0.973 – 1.26 0.124 319 1167 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.958 0.831 – 1.1 0.548 215 956 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.2 0.987 – 1.47 0.0671 129 860 exclusion phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.829 0.626 – 1.1 0.191 33 324 exclusion phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 1.14 0.816 – 1.59 0.444 45 335 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.13 1.01 – 1.27 0.0382 402 1533 exclusion phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 1.06 0.879 – 1.27 0.557 136 791 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.982 0.852 – 1.13 0.797 203 1058 exclusion phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 1.33 0.848 – 2.1 0.213 25 129 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.06 0.906 – 1.23 0.484 198 1024 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.38 1.04 – 1.83 0.0259 78 371 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.03 0.725 – 1.46 0.878 35 231 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.3 0.938 – 1.81 0.114 46 310 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.01 0.958 – 1.06 0.764 2266 4700 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.984 0.895 – 1.08 0.735 560 1670 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.03 0.902 – 1.17 0.688 312 1312 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.996 0.923 – 1.07 0.918 889 2658 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.02 0.943 – 1.1 0.645 894 2743 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.04 0.959 – 1.14 0.322 757 2262 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.03 0.941 – 1.13 0.52 583 2088 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1 0.926 – 1.08 0.993 845 2878 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 0.935 0.803 – 1.09 0.384 201 780 exclusion phecode
686.2 Impetigo Dermatologic 1.11 0.913 – 1.35 0.295 150 551 exclusion phecode
686.3 Pilonidal cyst Dermatologic 0.901 0.658 – 1.23 0.516 45 187 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 0.986 0.752 – 1.29 0.917 48 185 exclusion phecode
686.5 Pyoderma Dermatologic 0.878 0.535 – 1.44 0.606 27 90 exclusion phecode
687 Symptoms affecting skin Dermatologic 1.08 0.988 – 1.19 0.0881 708 1747 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.04 0.986 – 1.09 0.151 2645 3241 exclusion phecode
687.3 Changes in skin texture Dermatologic 1 0.846 – 1.19 0.956 175 492 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1 0.953 – 1.06 0.867 2490 3227 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.04 0.993 – 1.09 0.0907 2959 4486 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 1.04 0.983 – 1.1 0.169 1778 3886 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 1.04 0.983 – 1.1 0.17 1776 3885 exclusion phecode
691 Congenital anomalies of skin Dermatologic 1.05 0.888 – 1.25 0.549 186 670 exclusion phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 0.831 0.457 – 1.51 0.544 28 77 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 1.05 0.963 – 1.15 0.253 617 2301 exclusion phecode
694.1 Vitiligo Dermatologic 0.826 0.621 – 1.1 0.188 47 183 exclusion phecode
694.2 Other dyschromia Dermatologic 1.12 1.01 – 1.23 0.032 541 2110 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 0.754 0.544 – 1.05 0.0911 44 100 exclusion phecode
695 Erythematous conditions Dermatologic 1.04 0.979 – 1.11 0.205 1499 3775 exclusion phecode
695.1 Toxic erythema Dermatologic 0.916 0.607 – 1.38 0.677 26 84 exclusion phecode
695.2 Bullous dermatoses Dermatologic 0.887 0.612 – 1.29 0.527 33 104 exclusion phecode
695.3 Rosacea Dermatologic 1.05 0.963 – 1.15 0.256 628 2337 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.1 0.958 – 1.26 0.181 285 796 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.24 0.966 – 1.58 0.0916 103 286 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.09 0.956 – 1.25 0.191 272 751 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 1.01 0.873 – 1.18 0.847 213 784 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 1.06 0.936 – 1.2 0.364 365 1078 exclusion phecode
695.81 Erythema nodosum Dermatologic 1.15 0.657 – 2.03 0.618 29 56 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.1 0.953 – 1.27 0.192 256 928 exclusion phecode
696 Psoriasis and related disorders Dermatologic 1.11 0.995 – 1.24 0.0614 459 1676 exclusion phecode
696.3 Pityriasis Dermatologic 0.966 0.581 – 1.61 0.894 21 116 exclusion phecode
696.4 Psoriasis Dermatologic 1.1 0.988 – 1.23 0.0818 440 1597 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 1.09 0.971 – 1.21 0.149 407 1460 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 1.15 0.914 – 1.44 0.233 98 360 exclusion phecode
697 Sarcoidosis Dermatologic 0.943 0.779 – 1.14 0.546 109 411 exclusion phecode
698 Pruritus and related conditions Dermatologic 1.03 0.956 – 1.11 0.431 894 3530 exclusion phecode
700 Corns and callosities Dermatologic 1.05 0.953 – 1.15 0.338 630 1608 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.05 1 – 1.11 0.0424 2294 4804 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 1.14 0.972 – 1.34 0.106 223 809 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.11 0.997 – 1.23 0.0562 472 2873 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 1.07 0.9 – 1.28 0.425 172 841 exclusion phecode
701.4 Keloid scar Dermatologic 1.02 0.861 – 1.22 0.79 134 765 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 1.12 0.926 – 1.36 0.242 123 545 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.03 0.973 – 1.09 0.325 2319 3429 exclusion phecode
702.1 Actinic keratosis Dermatologic 1.03 0.961 – 1.09 0.446 1424 3616 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 1.01 0.957 – 1.07 0.674 1891 4333 exclusion phecode
702.4 Degenerative skin disorders Dermatologic 0.857 0.581 – 1.27 0.438 35 116 exclusion phecode
703 Diseases of nail, NOS Dermatologic 0.967 0.891 – 1.05 0.415 726 2318 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.997 0.896 – 1.11 0.96 390 1363 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 1.1 1.02 – 1.18 0.0084 1078 4209 exclusion phecode
704.1 Alopecia Dermatologic 1.03 0.93 – 1.13 0.599 519 2041 exclusion phecode
704.11 Alopecia Areata Dermatologic 1.13 0.753 – 1.69 0.562 31 139 exclusion phecode
704.12 Telogen effluvium Dermatologic 1.72 1.02 – 2.9 0.043 26 92 exclusion phecode
704.2 Hirsutism Dermatologic 1.21 0.953 – 1.52 0.119 98 419 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.13 1.03 – 1.25 0.00917 596 2509 exclusion phecode
705 Disorders of sweat glands Dermatologic 0.962 0.827 – 1.12 0.61 190 824 exclusion phecode
705.1 Dyshidrosis Dermatologic 0.913 0.685 – 1.22 0.533 56 236 exclusion phecode
705.3 Hidradenitis Dermatologic 0.8 0.628 – 1.02 0.0719 71 344 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.01 0.913 – 1.12 0.829 449 1536 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1.06 1.01 – 1.12 0.0309 1972 5135 exclusion phecode
706.1 Acne Dermatologic 1.07 0.992 – 1.16 0.0784 766 2934 exclusion phecode
706.2 Sebaceous cyst Dermatologic 1.05 0.977 – 1.13 0.186 929 3702 exclusion phecode
706.3 Seborrhea Dermatologic 1 0.649 – 1.55 0.989 30 92 exclusion phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 1.02 0.943 – 1.11 0.574 721 2323 exclusion phecode
707 Chronic ulcer of skin Dermatologic 0.995 0.931 – 1.06 0.883 1122 4217 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.07 0.953 – 1.2 0.253 381 1335 exclusion phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.02 0.921 – 1.12 0.735 496 1694 exclusion phecode
707.3 Chronic ulcer of unspecified site Dermatologic 0.97 0.889 – 1.06 0.498 621 2635 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 1.07 0.979 – 1.18 0.13 661 1797 exclusion phecode
709.2 Sicca syndrome Dermatologic 1.04 0.882 – 1.22 0.65 221 578 exclusion phecode
709.3 Systemic sclerosis Dermatologic 1.05 0.84 – 1.32 0.657 117 257 exclusion phecode
709.5 Dermatomyositis Dermatologic 0.75 0.472 – 1.19 0.224 38 124 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.28 0.851 – 1.91 0.238 43 106 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.03 0.924 – 1.16 0.555 441 1170 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.992 0.892 – 1.1 0.886 416 1426 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 0.98 0.879 – 1.09 0.72 404 1363 exclusion phecode
710.11 Acute osteomyelitis Musculoskeletal 1.02 0.878 – 1.19 0.782 226 676 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.998 0.853 – 1.17 0.98 187 628 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.989 0.885 – 1.1 0.843 387 1309 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 0.943 0.782 – 1.14 0.537 135 480 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.04 0.816 – 1.32 0.757 84 343 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.14 0.874 – 1.5 0.326 82 197 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.999 0.838 – 1.19 0.993 188 422 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.1 0.863 – 1.4 0.447 112 297 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 0.958 0.882 – 1.04 0.307 709 2259 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.926 0.843 – 1.02 0.113 528 1881 exclusion phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 1.33 0.82 – 2.14 0.251 27 95 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.998 0.902 – 1.11 0.975 499 1480 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.995 0.799 – 1.24 0.967 116 296 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.01 0.77 – 1.32 0.946 69 254 exclusion phecode
716 Other arthropathies Musculoskeletal 0.997 0.949 – 1.05 0.917 3548 3503 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.991 0.756 – 1.3 0.947 85 238 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.8 0.553 – 1.16 0.235 40 136 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 0.997 0.949 – 1.05 0.909 3524 3502 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.919 0.735 – 1.15 0.459 102 517 exclusion phecode
720 Spinal stenosis Musculoskeletal 1.01 0.949 – 1.08 0.687 1276 3424 exclusion phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1.03 0.953 – 1.11 0.476 937 2871 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1 0.946 – 1.06 0.997 2047 3887 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1 0.948 – 1.06 0.922 1947 3831 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.01 0.894 – 1.15 0.852 295 1054 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 0.96 0.762 – 1.21 0.726 113 334 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.02 0.964 – 1.08 0.51 2042 4026 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.998 0.934 – 1.07 0.943 1175 3729 exclusion phecode
722.3 Schmorl's nodes Musculoskeletal 0.956 0.683 – 1.34 0.795 57 129 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.04 0.977 – 1.11 0.218 1394 3683 exclusion phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.03 0.858 – 1.23 0.769 167 589 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.17 0.945 – 1.44 0.153 131 487 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.02 0.935 – 1.11 0.662 643 2365 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.02 0.9 – 1.15 0.791 351 1142 exclusion phecode
723.1 Torticollis Musculoskeletal 1.22 0.91 – 1.62 0.186 77 309 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.02 0.961 – 1.09 0.497 1493 3806 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 1 0.93 – 1.09 0.904 915 2762 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.954 0.809 – 1.13 0.579 200 541 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.11 0.973 – 1.26 0.125 334 1153 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 0.944 0.851 – 1.05 0.276 432 1680 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.02 0.969 – 1.08 0.437 3115 2710 exclusion phecode
726.1 Enthesopathy Musculoskeletal 1.01 0.955 – 1.07 0.718 2385 2703 exclusion phecode
726.2 Synoviopathy Musculoskeletal 1.03 0.906 – 1.18 0.627 325 943 exclusion phecode
726.3 Bursitis Musculoskeletal 0.939 0.86 – 1.03 0.163 697 1618 exclusion phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.982 0.877 – 1.1 0.758 417 1111 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.03 0.971 – 1.09 0.341 2319 2700 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.02 0.951 – 1.1 0.531 1067 2338 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 1.03 0.868 – 1.22 0.756 172 435 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.958 0.864 – 1.06 0.414 475 1341 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.94 0.789 – 1.12 0.483 195 426 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.983 0.905 – 1.07 0.695 760 2020 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.966 0.82 – 1.14 0.678 197 554 exclusion phecode
727.8 Plica syndrome Musculoskeletal 0.871 0.566 – 1.34 0.53 22 91 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.996 0.934 – 1.06 0.89 1594 2671 exclusion phecode
728.1 Muscular calcification and ossification Musculoskeletal 0.555 0.346 – 0.891 0.0148 22 82 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.01 0.804 – 1.27 0.92 94 271 exclusion phecode
728.7 Fasciitis Musculoskeletal 1.04 0.966 – 1.12 0.282 1034 2228 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.01 0.834 – 1.21 0.95 143 468 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1 0.939 – 1.07 0.917 1346 2541 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.648 0.388 – 1.08 0.0972 34 83 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.822 0.543 – 1.24 0.353 47 120 exclusion phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 0.758 0.423 – 1.36 0.35 15 60 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.889 0.715 – 1.11 0.29 94 334 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.865 0.665 – 1.12 0.278 72 395 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.828 0.605 – 1.13 0.236 51 226 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.76 0.825 – 3.75 0.144 14 109 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 1 0.943 – 1.07 0.887 1570 3404 exclusion phecode
733.2 Cyst of bone Musculoskeletal 0.994 0.694 – 1.43 0.976 43 222 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.934 0.788 – 1.11 0.429 155 632 exclusion phecode
733.6 Costochondritis Musculoskeletal 0.912 0.756 – 1.1 0.34 144 462 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.08 0.91 – 1.28 0.381 178 990 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.29 0.714 – 2.35 0.395 21 97 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1.02 0.956 – 1.09 0.542 1231 4316 exclusion phecode
735.1 Flat foot Musculoskeletal 1.06 0.917 – 1.22 0.449 229 931 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 1 0.909 – 1.1 0.983 539 1908 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.975 0.867 – 1.1 0.671 374 1284 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 1.07 0.872 – 1.31 0.53 133 639 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.04 0.939 – 1.15 0.474 508 2268 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 0.995 0.924 – 1.07 0.891 892 3816 exclusion phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.807 0.564 – 1.15 0.24 31 151 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 0.846 0.627 – 1.14 0.273 62 277 exclusion phecode
736.3 Acquired deformities of hip Musculoskeletal 0.955 0.538 – 1.7 0.876 16 69 exclusion phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.829 0.665 – 1.04 0.0983 80 462 exclusion phecode
736.5 Acquired deformities of knee Musculoskeletal 0.824 0.619 – 1.1 0.185 61 337 exclusion phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.934 0.768 – 1.14 0.499 114 465 exclusion phecode
737 Curvature of spine Musculoskeletal 1.04 0.94 – 1.16 0.425 439 2199 exclusion phecode
737.1 Kyphosis (acquired) Musculoskeletal 0.92 0.768 – 1.1 0.364 133 643 exclusion phecode
737.2 Lordosis (acquired) Musculoskeletal 0.974 0.557 – 1.7 0.926 18 98 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.08 0.956 – 1.22 0.212 317 1709 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.989 0.907 – 1.08 0.806 602 3389 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.942 0.838 – 1.06 0.313 317 1588 exclusion phecode
739 Contracture of joint Musculoskeletal 1.01 0.864 – 1.19 0.869 189 888 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.01 0.96 – 1.06 0.737 4185 3252 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.03 0.972 – 1.1 0.298 2184 3024 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.03 0.971 – 1.1 0.288 1936 2908 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.12 0.941 – 1.32 0.207 180 787 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.983 0.895 – 1.08 0.709 715 1405 exclusion phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 0.978 0.82 – 1.17 0.807 169 419 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.01 0.962 – 1.06 0.662 4049 3251 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.03 0.978 – 1.08 0.274 2592 4279 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 0.892 0.683 – 1.16 0.399 52 310 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.01 0.899 – 1.13 0.904 364 1573 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 1.01 0.936 – 1.08 0.837 965 2895 exclusion phecode
741.4 Joint effusions Musculoskeletal 1.04 0.96 – 1.12 0.364 873 2955 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.41 0.908 – 2.2 0.126 37 121 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.937 0.512 – 1.71 0.832 19 76 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.01 0.945 – 1.07 0.868 1334 4036 exclusion phecode
742.1 Loose body in joint Musculoskeletal 0.955 0.606 – 1.51 0.844 30 153 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.96 0.708 – 1.3 0.79 51 244 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 0.865 0.626 – 1.2 0.379 51 269 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 1.01 0.945 – 1.07 0.835 1275 3939 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.04 0.992 – 1.1 0.0996 2894 4512 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.05 0.969 – 1.13 0.254 1240 2592 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.05 0.971 – 1.13 0.226 1217 2571 exclusion phecode
743.12 Senile osteoporosis Musculoskeletal 1.07 0.914 – 1.24 0.414 295 683 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 1.02 0.836 – 1.24 0.855 149 400 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 0.998 0.895 – 1.11 0.97 432 1316 exclusion phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 0.993 0.843 – 1.17 0.931 202 562 exclusion phecode
743.22 Pathologic fracture of femur Musculoskeletal 0.978 0.71 – 1.35 0.891 52 160 exclusion phecode
743.4 Stress fracture Musculoskeletal 1.11 0.914 – 1.36 0.284 146 582 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.03 0.975 – 1.09 0.297 2398 4359 exclusion phecode
745 Pain in joint Musculoskeletal 1.05 0.999 – 1.11 0.0524 5274 2177 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.01 0.93 – 1.1 0.753 601 3560 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.05 0.947 – 1.15 0.383 471 2810 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.992 0.843 – 1.17 0.92 171 1044 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.05 0.905 – 1.22 0.523 214 1195 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.12 0.913 – 1.38 0.272 114 629 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.981 0.816 – 1.18 0.839 137 784 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.865 0.563 – 1.33 0.509 18 195 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.913 0.757 – 1.1 0.341 112 770 exclusion phecode
749.1 Cleft palate Congenital Anomalies 0.6 0.293 – 1.23 0.162 5 103 exclusion phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.688 0.426 – 1.11 0.128 22 132 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 0.997 0.88 – 1.13 0.959 330 1424 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.95 0.748 – 1.21 0.673 95 590 exclusion phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.867 0.598 – 1.26 0.449 37 186 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.961 0.597 – 1.55 0.869 17 141 exclusion phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 1.05 0.725 – 1.51 0.807 34 213 exclusion phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 1.7 0.781 – 3.72 0.181 15 106 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.04 0.9 – 1.21 0.58 237 865 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.01 0.83 – 1.23 0.905 143 520 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.02 0.831 – 1.26 0.827 97 367 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.08 0.984 – 1.19 0.104 539 3039 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.15 0.949 – 1.39 0.154 159 843 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.14 0.926 – 1.41 0.214 129 645 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.06 0.652 – 1.73 0.806 22 172 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.02 0.91 – 1.14 0.771 386 2159 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 1.05 0.923 – 1.19 0.465 291 1572 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.06 0.817 – 1.37 0.674 77 421 exclusion phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.72 1.07 – 2.77 0.0254 34 235 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.984 0.875 – 1.11 0.793 303 1831 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 0.941 0.826 – 1.07 0.362 236 1518 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.932 0.693 – 1.25 0.639 43 268 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.12 0.85 – 1.47 0.423 69 337 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.794 0.615 – 1.03 0.0791 61 323 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.636 0.371 – 1.09 0.1 17 91 exclusion phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 0.852 0.534 – 1.36 0.504 19 84 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.968 0.866 – 1.08 0.563 359 1962 exclusion phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 1.29 0.887 – 1.89 0.18 45 238 exclusion phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 0.948 0.803 – 1.12 0.528 161 967 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.891 0.767 – 1.03 0.128 191 1091 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.942 0.779 – 1.14 0.539 107 563 exclusion phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 0.764 0.428 – 1.37 0.365 16 105 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.894 0.693 – 1.15 0.391 67 427 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.08 0.741 – 1.58 0.683 34 249 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.05 0.942 – 1.18 0.357 406 2014 exclusion phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 1.31 0.798 – 2.16 0.284 24 108 exclusion phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 0.585 0.291 – 1.18 0.133 11 66 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.973 0.772 – 1.23 0.813 102 447 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.05 0.919 – 1.19 0.482 293 1535 exclusion phecode
757 Congenital anomalies of the integument Congenital Anomalies 0.978 0.796 – 1.2 0.831 106 673 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.08 0.796 – 1.45 0.636 52 290 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.992 0.731 – 1.35 0.957 37 228 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.17 0.966 – 1.43 0.107 135 854 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.936 0.54 – 1.62 0.812 15 122 exclusion phecode
760 Back pain Symptoms 1.04 0.994 – 1.09 0.0889 4723 2729 exclusion phecode
761 Cervicalgia Symptoms 0.991 0.943 – 1.04 0.722 2345 5068 exclusion phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 1.03 0.969 – 1.1 0.314 1292 4239 exclusion phecode
764 Sciatica Symptoms 1.05 0.985 – 1.12 0.131 1296 4216 exclusion phecode
765 Cervical radiculitis Symptoms 1 0.915 – 1.09 0.992 624 2452 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.03 0.976 – 1.09 0.267 1728 4727 exclusion phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 0.89 0.694 – 1.14 0.358 67 167 exclusion phecode
769 Nonallopathic lesions NEC Symptoms 0.958 0.868 – 1.06 0.4 459 1951 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 0.974 0.924 – 1.03 0.318 2022 4695 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.01 0.949 – 1.07 0.851 1683 4089 exclusion phecode
771.1 Swelling of limb Symptoms 0.969 0.92 – 1.02 0.251 2165 4088 exclusion phecode
771.2 Cramp of limb Symptoms 0.961 0.864 – 1.07 0.459 504 1418 exclusion phecode
772 Symptoms of the muscles Symptoms 0.993 0.915 – 1.08 0.863 706 2820 exclusion phecode
772.1 Muscular wasting and disuse atrophy Symptoms 0.975 0.818 – 1.16 0.782 138 509 exclusion phecode
772.2 Spasm of muscle Symptoms 1.02 0.944 – 1.1 0.621 853 3090 exclusion phecode
772.3 Muscle weakness Symptoms 0.991 0.928 – 1.06 0.782 1178 3828 exclusion phecode
772.4 Rhabdomyolysis Symptoms 1.06 0.784 – 1.43 0.715 61 217 exclusion phecode
772.6 Facial weakness Symptoms 0.972 0.824 – 1.15 0.741 178 661 exclusion phecode
780 Hypothermia/Chills Symptoms 0.89 0.772 – 1.03 0.108 225 792 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.01 0.943 – 1.07 0.85 1199 3965 exclusion phecode
781.1 Loss of height Symptoms 1.35 0.913 – 1.98 0.133 50 221 exclusion phecode
781.2 Abnormal posture Symptoms 0.819 0.485 – 1.38 0.455 20 73 exclusion phecode
782.3 Edema Symptoms 1.04 0.984 – 1.09 0.185 2338 4684 exclusion phecode
782.6 Pallor and flushing Symptoms 0.963 0.851 – 1.09 0.555 288 1289 exclusion phecode
783 Fever of unknown origin Symptoms 1.03 0.978 – 1.08 0.275 2075 5320 exclusion phecode
783.1 Postprocedural fever Symptoms 0.932 0.733 – 1.19 0.568 78 367 exclusion phecode
785 Abdominal pain Symptoms 1.04 0.992 – 1.09 0.0987 4971 2479 exclusion phecode
788 Syncope and collapse Symptoms 1.04 0.985 – 1.11 0.145 1491 5207 exclusion phecode
789 Nausea and vomiting Symptoms 1 0.956 – 1.05 0.953 3269 4166 exclusion phecode
789.1 Persistent vomiting Symptoms 1.08 0.947 – 1.23 0.258 335 945 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.03 0.958 – 1.11 0.434 1029 2729 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.15 0.912 – 1.44 0.242 120 286 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.04 0.994 – 1.1 0.0832 2922 4162 exclusion phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 0.924 0.764 – 1.12 0.411 154 354 exclusion phecode
790.9 Abnormal arterial blood gases Symptoms 1.12 0.801 – 1.57 0.507 63 182 exclusion phecode
791 Gangrene Symptoms 0.997 0.817 – 1.22 0.975 107 544 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 1.08 0.99 – 1.18 0.083 741 2174 exclusion phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 1.09 0.961 – 1.24 0.174 304 1357 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.951 0.777 – 1.16 0.621 122 878 exclusion phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 1.01 0.918 – 1.1 0.887 552 3355 exclusion phecode
795.8 Abnormal tumor markers Symptoms 0.952 0.852 – 1.06 0.382 340 2467 exclusion phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 0.89 0.557 – 1.42 0.625 17 87 exclusion phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 1.03 0.742 – 1.42 0.872 39 351 exclusion phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.979 0.876 – 1.1 0.713 446 1215 exclusion phecode
797 Shock Symptoms 1.02 0.88 – 1.17 0.833 243 987 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.18 0.912 – 1.54 0.203 90 400 exclusion phecode
798 Malaise and fatigue Symptoms 1.01 0.969 – 1.06 0.536 4250 3200 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 0.969 0.895 – 1.05 0.437 841 1802 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 0.992 0.91 – 1.08 0.856 664 3182 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.09 0.912 – 1.3 0.352 187 727 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.973 0.834 – 1.13 0.725 220 897 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.866 0.758 – 0.99 0.0356 238 1201 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.978 0.776 – 1.23 0.851 98 471 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.965 0.892 – 1.04 0.381 778 3230 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 0.969 0.858 – 1.09 0.61 316 1535 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.05 0.868 – 1.28 0.601 121 527 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 1.03 0.939 – 1.13 0.521 536 2770 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 0.991 0.85 – 1.16 0.908 213 1002 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.03 0.911 – 1.17 0.613 299 1566 exclusion phecode
803.21 Colles' fracture Injuries & Poisonings 1.04 0.822 – 1.33 0.719 87 397 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.07 0.871 – 1.31 0.527 122 649 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.972 0.882 – 1.07 0.56 445 2180 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.931 0.843 – 1.03 0.164 470 1894 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.02 0.877 – 1.18 0.82 263 967 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.01 0.938 – 1.1 0.723 795 3932 exclusion phecode
816 Cerebral laceration and contusion Injuries & Poisonings 1.37 0.737 – 2.55 0.32 21 74 exclusion phecode
817 Concussion Injuries & Poisonings 0.921 0.822 – 1.03 0.156 317 1489 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.984 0.81 – 1.2 0.871 116 560 exclusion phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.868 0.598 – 1.26 0.459 37 159 exclusion phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.07 0.706 – 1.63 0.745 31 178 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.99 0.91 – 1.08 0.823 660 3298 exclusion phecode
830 Dislocation Injuries & Poisonings 0.972 0.907 – 1.04 0.423 967 5142 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.992 0.906 – 1.09 0.856 560 3172 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.925 0.775 – 1.1 0.387 128 779 exclusion phecode
840 Sprains and strains Injuries & Poisonings 1.02 0.971 – 1.08 0.412 2143 5037 exclusion phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 1.02 0.878 – 1.2 0.758 194 755 exclusion phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.943 0.862 – 1.03 0.202 542 2349 exclusion phecode
840.3 Joint/ligament sprain Injuries & Poisonings 1.01 0.933 – 1.1 0.73 670 3222 exclusion phecode
841 Sprains and strains of back and neck Injuries & Poisonings 1.01 0.923 – 1.11 0.771 570 2159 exclusion phecode
842 Other sprains and strains Injuries & Poisonings 0.996 0.895 – 1.11 0.943 428 1871 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.04 0.952 – 1.14 0.381 571 2961 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.02 0.946 – 1.1 0.614 860 3711 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.16 0.976 – 1.39 0.0907 198 608 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.06 0.972 – 1.15 0.202 716 2763 exclusion phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 0.98 0.769 – 1.25 0.871 68 383 exclusion phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.12 0.881 – 1.44 0.346 85 443 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.07 0.951 – 1.2 0.265 342 1807 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.982 0.891 – 1.08 0.721 441 2856 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.03 0.938 – 1.12 0.573 573 2914 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.18 0.884 – 1.56 0.266 79 281 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.03 0.962 – 1.09 0.438 1175 5026 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.18 0.84 – 1.65 0.343 48 278 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 1.02 0.738 – 1.41 0.899 43 192 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.01 0.901 – 1.13 0.888 373 1852 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.775 0.577 – 1.04 0.0905 39 315 exclusion phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 0.909 0.683 – 1.21 0.514 62 376 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.807 0.571 – 1.14 0.224 30 278 exclusion phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.88 1.2 – 2.93 0.00567 32 193 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.07 0.998 – 1.14 0.0564 1135 4530 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.06 0.895 – 1.26 0.488 175 790 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.05 0.928 – 1.19 0.439 330 1396 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.12 0.955 – 1.32 0.16 199 793 exclusion phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1.06 0.863 – 1.3 0.593 128 513 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.11 0.926 – 1.32 0.265 158 761 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.02 0.766 – 1.36 0.884 52 226 exclusion phecode
875 Non-healing surgical wound Injuries & Poisonings 1.11 0.921 – 1.35 0.264 150 796 exclusion phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.04 0.897 – 1.2 0.628 272 1170 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.05 0.916 – 1.21 0.466 234 1506 exclusion phecode
910 Superficial injury, infected Injuries & Poisonings 1.01 0.705 – 1.44 0.973 46 192 exclusion phecode
911 Blister Injuries & Poisonings 1.19 0.971 – 1.45 0.0941 136 623 exclusion phecode
912 Insect bite Injuries & Poisonings 0.888 0.753 – 1.05 0.156 172 828 exclusion phecode
913 Toxic effect of venom Injuries & Poisonings 1.06 0.858 – 1.32 0.573 117 564 exclusion phecode
916 Contusion Injuries & Poisonings 0.997 0.942 – 1.05 0.914 1563 5396 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 1.01 0.883 – 1.17 0.835 267 801 exclusion phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.966 0.831 – 1.12 0.656 207 783 exclusion phecode
938 Dermatitis due to solar radiation Dermatologic 1.06 0.997 – 1.12 0.0612 1842 3018 exclusion phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 1.19 0.913 – 1.56 0.196 84 245 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 1.06 0.997 – 1.12 0.0609 1776 2978 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.06 1.01 – 1.12 0.0316 2309 3184 exclusion phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 1.04 0.721 – 1.5 0.834 31 105 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.91 0.73 – 1.13 0.4 88 215 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.946 0.774 – 1.16 0.588 118 296 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.999 0.85 – 1.17 0.986 199 520 exclusion phecode
947 Urticaria Dermatologic 1.02 0.92 – 1.14 0.657 434 1198 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.06 1 – 1.12 0.0404 2264 3179 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.08 0.886 – 1.33 0.431 137 732 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.22 0.776 – 1.93 0.385 26 171 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.05 0.94 – 1.18 0.366 370 1891 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.16 0.834 – 1.62 0.372 50 281 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.01 0.648 – 1.56 0.978 31 154 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.05 0.972 – 1.14 0.207 811 2814 exclusion phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 1.01 0.824 – 1.24 0.91 137 447 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.04 0.942 – 1.15 0.438 509 2056 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.01 0.888 – 1.16 0.831 237 745 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.991 0.883 – 1.11 0.874 341 1463 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 0.955 0.845 – 1.08 0.465 370 1077 exclusion phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 0.992 0.824 – 1.19 0.933 188 501 exclusion phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 0.85 0.539 – 1.34 0.483 36 119 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 0.928 0.795 – 1.08 0.345 204 659 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.07 0.987 – 1.17 0.0963 744 3085 exclusion phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.07 0.985 – 1.17 0.109 715 3022 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.01 0.891 – 1.13 0.928 366 1000 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.992 0.879 – 1.12 0.89 348 958 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.918 0.814 – 1.03 0.159 328 1111 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.945 0.863 – 1.04 0.227 548 1903 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.69 0.448 – 1.06 0.0925 30 146 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.99 0.697 – 1.41 0.955 46 128 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.03 0.921 – 1.15 0.628 378 1606 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 0.907 0.737 – 1.12 0.354 140 342 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.4 0.801 – 2.44 0.238 30 106 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.904 0.749 – 1.09 0.292 144 419 exclusion phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 0.82 0.582 – 1.16 0.259 38 107 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.865 0.616 – 1.22 0.404 54 155 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.956 0.716 – 1.28 0.758 66 160 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.58 0.963 – 2.59 0.0704 27 104 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.677 0.463 – 0.99 0.0445 29 96 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.919 0.848 – 0.995 0.0381 664 2271 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.01 0.944 – 1.07 0.827 1253 3889 exclusion phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 0.964 0.87 – 1.07 0.484 392 2255 exclusion phecode
985 Toxic effect of other metals Injuries & Poisonings 1.13 0.701 – 1.81 0.623 29 103 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.48 1.01 – 2.18 0.0468 48 232 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.01 0.937 – 1.09 0.746 768 4713 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.05 0.969 – 1.13 0.249 899 3424 exclusion phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.09 0.881 – 1.35 0.429 122 470 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.04 0.966 – 1.13 0.277 861 3260 exclusion phecode
994.21 Septic shock Injuries & Poisonings 1.09 0.947 – 1.26 0.225 272 940 exclusion phecode
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