Scores · Skin Cancer PRSweb

PRS scores

Release skincancerprsweb_20190614 20 total rows rendered

Use the filters below to narrow the main PRS catalog. Binary traits report percentile odds ratios, while quantitative traits report percentile beta values. Click any sortable column header to reorder rows; this table defaults to increasing p-value.

Skin Cancer PRSweb lists the preserved evaluation rows here. When a model has both MGI and UKB phenome follow-up, the same score row now links to both cohort-specific PheWAS views instead of showing UKB as a second evaluation row.

Filter defaults and flag guide

By default the row filters open on retained rows so the table starts with the models most likely to be useful for comparison. “Hide non-nominal rows” keeps only rows that were nominally significant in the preserved release, and “Hide flagged rows” removes reversed-effect or underpowered rows. Turn either filter off when you need the full preserved table.

Flag guide: nominal = passed the preserved release's nominal threshold; weak = did not; reversed effect = observed direction opposite the expected effect direction; retained = nominal and warning-free. When the trait list feels too long, use the free-text Search box first.

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Top percentile effect column

Trait code	Trait	Cohort	Method	GWAS source	# SNPs	P value	R² / pseudo-R²	Brier	AAUC	Top 1% effect	Top 2% effect	Top 5% effect	Top 10% effect	Top 25% effect	Flags	Links
172	Skin cancer	MGI	Fixed threshold (5e-07)	UK Biobank summary statistics	63	3.1e-70		0.14	0.58 0.57-0.59	OR	OR	OR	OR	OR	Binary nominal	detail PheWAS weights
172	Skin cancer	MGI	Fixed threshold (5e-08)	UK Biobank summary statistics	50	5.7e-70		0.14	0.58 0.57-0.59	OR	OR	OR	OR	OR	Binary nominal	detail PheWAS weights
172	Skin cancer	MGI	Fixed threshold (5e-06)	UK Biobank summary statistics	104	1e-66		0.14	0.58 0.57-0.59	OR	OR	OR	OR	OR	Binary nominal	detail PheWAS weights
172.21	Basal cell carcinoma	MGI	GWAS Catalog	GWAS Catalog	32	3.6e-65		0.091	0.64 0.62-0.66	OR	OR	OR	OR	OR	Binary nominal	detail MGI PheWAS UKB PheWAS weights
172	Skin cancer	MGI	Fixed threshold (5e-09)	UK Biobank summary statistics	40	6.1e-65		0.14	0.58 0.57-0.59	OR	OR	OR	OR	OR	Binary nominal	detail PheWAS weights
172	Skin cancer	MGI	Fixed threshold (5e-05)	UK Biobank summary statistics	309	6.8e-63		0.14	0.58 0.57-0.59	OR	OR	OR	OR	OR	Binary nominal	detail PheWAS weights
172.21	Basal cell carcinoma GWAS Catalog	MGI	Latest GWAS	Latest published GWAS	28	2.8e-60		0.091	0.63 0.61-0.65	OR	OR	OR	OR	OR	Binary nominal	detail MGI PheWAS UKB PheWAS weights
172.11	Melanomas of skin Melanoma	MGI	GWAS Catalog	GWAS Catalog	29	1.3e-56		0.093	0.61 0.59-0.62	OR	OR	OR	OR	OR	Binary nominal	detail MGI PheWAS UKB PheWAS weights
172.11	Melanomas of skin Melanoma	MGI	Latest GWAS	Latest published GWAS	20	1.2e-55		0.093	0.6 0.59-0.62	OR	OR	OR	OR	OR	Binary nominal	detail MGI PheWAS UKB PheWAS weights
172	Skin cancer	MGI	LDpred (1%)	UK Biobank summary statistics		3e-55	0.017	0.14	0.57 0.56-0.58	OR	OR	OR	OR	OR	Binary nominal	detail PheWAS
172.11	Melanomas of skin Melanoma	MGI	LDpred (0.001%)	UK Biobank summary statistics		3.2e-50	0.024	0.093	0.6 0.58-0.62	OR	OR	OR	OR	OR	Binary nominal	detail PheWAS
172.11	Melanomas of skin Melanoma	MGI	Fixed threshold (5e-07)	UK Biobank summary statistics	13	6.5e-47		0.093	0.59 0.58-0.61	OR	OR	OR	OR	OR	Binary nominal	detail PheWAS weights
172.11	Melanomas of skin Melanoma	MGI	Fixed threshold (5e-08)	UK Biobank summary statistics	9	1.7e-46		0.093	0.59 0.58-0.61	OR	OR	OR	OR	OR	Binary nominal	detail PheWAS weights
172.11	Melanomas of skin Melanoma	MGI	Fixed threshold (5e-06)	UK Biobank summary statistics	27	3.6e-36		0.093	0.58 0.56-0.6	OR	OR	OR	OR	OR	Binary nominal	detail PheWAS weights
172.11	Melanomas of skin Melanoma	MGI	Fixed threshold (5e-09)	UK Biobank summary statistics	6	3.1e-34		0.093	0.58 0.56-0.59	OR	OR	OR	OR	OR	Binary nominal	detail PheWAS weights
172	Skin cancer	MGI	Fixed threshold (5e-04)	UK Biobank summary statistics	1473	1.9e-30		0.14	0.56 0.54-0.57	OR	OR	OR	OR	OR	Binary nominal	detail PheWAS weights
172.22	Squamous cell carcinoma GWAS Catalog	MGI	Latest GWAS	Latest published GWAS	10	2.1e-21		0.091	0.59 0.56-0.61	OR	OR	OR	OR	OR	Binary nominal	detail MGI PheWAS UKB PheWAS weights
172.11	Melanomas of skin Melanoma	MGI	Fixed threshold (5e-05)	UK Biobank summary statistics	156	5.8e-20		0.094	0.56 0.54-0.58	OR	OR	OR	OR	OR	Binary nominal	detail PheWAS weights
172.22	Squamous cell carcinoma	MGI	GWAS Catalog	GWAS Catalog	18	1.8e-10		0.091	0.55 0.53-0.58	OR	OR	OR	OR	OR	Binary nominal	detail MGI PheWAS UKB PheWAS weights
172.11	Melanomas of skin Melanoma	MGI	Fixed threshold (5e-04)	UK Biobank summary statistics	1193	1.1e-4		0.094	0.54 0.52-0.55	OR	OR	OR	OR	OR	Binary nominal	detail PheWAS weights

PRS scores

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