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Global Lipids Genetics Consortium Results

Meta-Analysis Tables

The tables below summarize the results of the meta-analysis of exome chip in > 300,000 primarily European samples for HDL cholesterol, LDL cholesterol, total cholesterol and triglyceride levels.

Result Files

EXOME CHIP META-ANALYSIS IN PRIMARILY EUROPEANS (N= ~300,000)

Reference Liu DJ, Peloso GM, Butterworth A, Saleheen D, Zhang H, Schmidt EM, Mahajan A, Fritsche L, [many additional authors], Deloukas P, Musunuru K, Cowan C, McCarthy MI, Willer CJ, Kathiresan S. Biological and clinical insights from genomic analysis of plasma lipids in > 300,000 individuals. Nat Genet (in press).

LDL Cholesterol HDL Cholesterol Triglycerides Total Cholesterol

EXOME CHIP META-ANALYSIS IN EUROPEANS (N= ~300,000) + EAST ASIANS (N= ~47,000)

Reference Lu X, Peloso GM, Liu DJ, Wu Y, Zhang H, Li J, Tang CS, Dorajoo R, [many additional authors], Kathiresan S, Mohlke KL, Wu T, Sham PC, Gu D, Willer C. Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants contributing to lipid levels and coronary artery disease. Nat Genet (in press).

LDL Cholesterol HDL Cholesterol Triglycerides Total Cholesterol

Columns in Result Files

Column Label Description
SNP_hg18 Marker name in build hg18.
SNP_hg19 Marker name in build hg19.
rsid Marker name in rsid format.
A1 Effect allele.
A2 Other allele.
Beta Effect size.
SE Standard Error for Beta.
N The number of individuals analyzed for this marker.
P-value P-value after doing genomic control.
Freq.A1.1000G.EAS Frequency of allele A1 from 1000G EAS sample.

Using our GLGC data in LocusZoom (http://csg.sph.umich.edu/locuszoom).

Please e-mail Goncalo Abecasis or Cristen Willer with comments or suggestions.


 
 

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