Gonçalo's Software
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The following software packages can be downloaded freely. If you
find them useful, please fill out the accompanying registration form
and cite them in your work.
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Merlin |
Fast pedigree analyses, including non-parametric linkage, error
detection and haplotyping.
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LAMP |
Powerful parametric tests of association for pedigree and case-control
data, that provide an alternative to standard approaches based on
transmission disequilibrium. Can also be used to maximize LOD scores
over mode of inheritance.
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MACH |
Rapid high-quality haplotyping and genotype inference. Currently in
beta release.
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QTDT |
Linkage disequilibrium and association analyses for quantitative
traits. |
GOLD |
A graphical package for the overview of linkage disequilibrium. |
PedStats |
A utility for summarizing the contents of pedigree files with the
ability to produce graphical output in PDF format.
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GRR |
A graphical tool for identifying relationship errors in genome scan
data. |
CaTS |
Graphical power calculator for case-control association studies, including
two stage studies.
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GAS |
Graphical web interface for one-stage association studies. Adapted from CaTS algorithms.
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Metal |
Meta-Analysis Tool for genome-wide association scans.
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FUGUE |
Haplotype frequency estimation in families and unrelated individuals.
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Pseudo |
This is a companion tool for Merlin that facilitates gene-dropping simulations.
In addition to calculating summary statistics for standard gene-dropping
simulations, Pseudo can read in simulated LOD scores for individual families
and shuffle them to create a series of "Pseudo" replicates.
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Additional code.
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SNP-HWE |
Routines for exact SNP tests of Hardy-Weinberg Equilibrium.
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