About GAS Power Calculator

This Genetic Association Study (GAS) Power Calculator is a simple interface that can be used to compute statistical power for large one-stage genetic association studies. The underlying method is derived from the CaTS power calculator for two-stage association studies (2006).

Inputs

Sample Size

Cases/Controls = 1.000
Cases
Controls

Study Design

Significance Level

Disease Model

Prevalence
Disease Allele Frequency
Genotype Relative Risk

Graph

Statistical Power vs.
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Results

Expected power for a one-stage study
0.995
Expected disease allele frequency
Cases
0.600
Controls
0.489
Probability of disease
Genotype A/A [with frequency 0.250]
0.144
Genotype A/B [with frequency 0.500]
0.096
Genotype B/B [with frequency 0.250]
0.064

© 2017 Jennifer Li Johnson | University of Michigan

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