2004-2007 | Postdoctoral Fellow Statistical Genetics | University of Michigan Center for Statsistical Genetics, Ann Arbor, MI (Advisor: Gonçalo Abecasis) |
2000-2004 | Ph.D. Biostatistics | Johns Hopkins Bloomberg School of
Public Health, Baltimore, MD (Advisor: Karl Broman,
Kung-Yee Liang) Thesis: Robust quantitative trait linkage analysis in extended human pedigrees |
1998-2000 | M.S. Biomedical Sciences | Creighton University Department of Biomedical Sciences, Omaha, NE (Advisor: Hong-Weng Deng) |
1996-1998 | M.S. Image Processing | Peking University Center for Information Sciences, Beijing, China |
1992-1996 | B.S. Probability and Statistics | Peking University Department of Probability and Statistics, Beijing, China |
Chen WM, Abecasis GR (2007) Family-based association tests for genome wide association scans. Am J Hum Genet 81:913-926 [PDF]
Scuteri A, Sanna S, Chen WM, Uda M, Albai G, et al. (2007) Genome wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet 3(7):e115 [PDF]
Burdick JT, Chen WM, Abecasis GR, Cheung VG (2006) In silico method for inferring genotypes in pedigrees. Nat Genet 38:1002-1004 [PDF]
Pilia G, Chen WM, et al. (2006) Heritability of cardiovascular and personality traits in 6,148 Sardinians. PLoS Genet 2(8):1207-1223 [PDF]
Chen WM, Abecasis GR (2006) Estimating the power of variance component linkage analysis in large pedigrees. Genet Epidemiol 30:471-484 [PDF]
Chen WM, Broman KW and Liang KY (2005) Power and robustness of linkage tests for quantitative traits in general pedigrees. Genet Epidemiol 28:11-23 [Abstract] [PDF]
Chen WM, Broman KW and Liang KY (2004) Quantitative trait linkage analysis by generalized estimating equations: unification of variance components and Haseman-Elston regression. Genet Epidemiol 26:265-272 [Abstract] [PDF]
Fallin D, Beaty T, Liang KY and Chen W (2002) "Power comparisons for genotypic vs. allelic TDT methods with >2 alleles". Genet Epidemiol 23:458-461 [PDF]
Chen WM and Deng HW (2001) A general and accurate approach for computing the statistical power of the transmission disequilibrium test for complex disease genes. Genet Epidemiol 21:53-67 [Abstract] [PDF]
Deng HW, Chen WM, Conway T, Zhou Y, Davies KM, Stegman MR, Deng H and Recker RR (2000) Determination of bone mineral density of the hip and spine in human pedigrees by genetic and life-style factors. Genet Epidemiol 19:160-177 [Abstract] [PDF]
Deng HW, Chen WM and Recker RR (2000) QTL fine mapping by measuring and testing for Hardy-Weinberg and linkage disequilibrium at a series of linked marker loci in extreme samples of populations. Am J Hum Genet 66:1027-1045 [Abstract] [PDF]
Ghost | Software for family-based genomewide association analysis |
POLY | POLY implements polygenic analysis for quantitative traits. It also provides power calculation for the quantitative trait linkage analysis. |
GeneFinder | GeneFinder implements multipoint linkage methods for localizing susceptibility genes of complex diseases using Generalized Estimating Equations approach |
TDT-PC | TDT Power Calculator provides sample size and power calculation for the Transmission/Disequilibrium Test in association study. |