libStatGen Software  1
CigarHelper.h
00001 /*
00002  *  Copyright (C) 2011  Regents of the University of Michigan
00003  *
00004  *   This program is free software: you can redistribute it and/or modify
00005  *   it under the terms of the GNU General Public License as published by
00006  *   the Free Software Foundation, either version 3 of the License, or
00007  *   (at your option) any later version.
00008  *
00009  *   This program is distributed in the hope that it will be useful,
00010  *   but WITHOUT ANY WARRANTY; without even the implied warranty of
00011  *   MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
00012  *   GNU General Public License for more details.
00013  *
00014  *   You should have received a copy of the GNU General Public License
00015  *   along with this program.  If not, see <http://www.gnu.org/licenses/>.
00016  */
00017 
00018 #ifndef __CIGAR_HELPER_H__
00019 #define __CIGAR_HELPER_H__
00020 
00021 #include "SamRecord.h"
00022 
00023 /// Class for helping to filter a SAM/BAM record.
00024 class CigarHelper
00025 {
00026 public:
00027     static const int32_t NO_CLIP = -1;
00028 
00029     /// Soft clip the cigar from the beginning of the read at the specified
00030     /// reference position.  If the clip position is deleted/skipped
00031     /// or is immediately followed by a deletion/skip/pad/insert, that entire 
00032     /// CIGAR operation is also removed.
00033     /// Nothing is clipped if the reference position is before the read starts,
00034     /// everything is clipped if the reference position is after the read ends.
00035     /// \param record record to calculate the clip for.
00036     /// \param refPosition0Based 0-based reference position to end the clip at
00037     /// \param newCigar cigar object to set with the updated cigar.
00038     /// \param new0BasedPosition new 0-based reference position of the read.
00039     /// \param read position where the clip ends (last clipped position) or 
00040     //         NO_CLIP if nothing is clipped.
00041     static int32_t softClipBeginByRefPos(SamRecord& record, 
00042                                          int32_t refPosition0Based,
00043                                          CigarRoller& newCigar,
00044                                          int32_t &new0BasedPosition);
00045 
00046     /// Soft clip the cigar from the back of the read at the specified
00047     /// reference position.  If the clip position is deleted/skipped
00048     /// or is immediately preceded by a deletion/skip/pad, that entire CIGAR
00049     /// operation is also removed.  If the clip position is immediately
00050     /// preceded by an insertion, the insertion is left in the CIGAR.
00051     /// Nothing is clipped if the reference position is after the read ends,
00052     /// everything is clipped if the reference position is before the read
00053     /// starts (including insertions).
00054     /// \param record record to calculate the clip for.
00055     /// \param refPosition0Based 0-based reference position to start clip at
00056     /// \param newCigar cigar object to set with the updated cigar.
00057     /// \param read position where the clip starts or 
00058     //         NO_CLIP if nothing is clipped.
00059     static int32_t softClipEndByRefPos(SamRecord& record, 
00060                                        int32_t refPosition0Based,
00061                                        CigarRoller& newCigar);
00062 };
00063 
00064 #endif
00065 
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